Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P09_F_I17
(922 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X05344-1|CAA28955.1| 412|Homo sapiens cathepsin D protein. 242 1e-63
M63138-1|AAA51922.1| 412|Homo sapiens cathepsin D protein. 242 1e-63
M11233-1|AAB59529.1| 412|Homo sapiens CTSD protein. 242 1e-63
CR456947-1|CAG33228.1| 412|Homo sapiens CTSD protein. 242 1e-63
BT020155-1|AAV38957.1| 412|Homo sapiens cathepsin D (lysosomal ... 242 1e-63
BT006910-1|AAP35556.1| 412|Homo sapiens cathepsin D (lysosomal ... 242 1e-63
BC016320-1|AAH16320.1| 412|Homo sapiens cathepsin D protein. 242 1e-63
BC017842-1|AAH17842.1| 420|Homo sapiens napsin A aspartic pepti... 219 9e-57
AF200345-1|AAF17081.1| 420|Homo sapiens aspartyl protease 4 pro... 219 1e-56
AF098484-1|AAD13215.1| 420|Homo sapiens napsin 1 precursor prot... 219 1e-56
AF090386-1|AAD04917.1| 420|Homo sapiens napsin A protein. 219 1e-56
BC111705-1|AAI11706.1| 464|Homo sapiens NAPSB protein protein. 201 2e-51
AF200344-1|AAF17080.1| 450|Homo sapiens aspartyl protease 3 pro... 201 2e-51
M10152-1|AAD03461.1| 406|Homo sapiens renin protein. 193 9e-49
L00073-1|AAA60363.1| 406|Homo sapiens renin protein. 193 9e-49
CR536498-1|CAG38737.1| 406|Homo sapiens REN protein. 193 9e-49
BC047752-1|AAH47752.1| 406|Homo sapiens renin protein. 193 9e-49
BC033474-1|AAH33474.1| 406|Homo sapiens renin protein. 193 9e-49
AL592146-1|CAI16594.1| 406|Homo sapiens renin protein. 193 9e-49
AL592114-1|CAH71224.1| 406|Homo sapiens renin protein. 193 9e-49
M84424-1|AAA52300.1| 396|Homo sapiens cathepsin E protein. 192 2e-48
M26901-1|AAA60364.1| 403|Homo sapiens renin protein. 192 2e-48
J05036-1|AAA52130.1| 396|Homo sapiens CTSE protein. 192 2e-48
BX571818-5|CAH73265.1| 363|Homo sapiens cathepsin E protein. 192 2e-48
BX571818-4|CAH73264.1| 396|Homo sapiens cathepsin E protein. 192 2e-48
BC042537-1|AAH42537.1| 396|Homo sapiens cathepsin E protein. 192 2e-48
AY436324-1|AAR03502.1| 403|Homo sapiens renin protein. 192 2e-48
AJ250717-1|CAB82850.1| 396|Homo sapiens procathepsin E protein. 192 2e-48
AJ250716-1|CAB82849.1| 363|Homo sapiens cathepsin E, alternativ... 192 2e-48
U75272-1|AAB18273.1| 388|Homo sapiens gastricsin protein. 171 3e-42
M23077-1|AAA60063.1| 388|Homo sapiens pepsinogen C protein. 171 3e-42
M18667-1|AAA60062.1| 385|Homo sapiens pepsinogen protein. 171 3e-42
J04443-1|AAA60074.1| 388|Homo sapiens pepsinogen protein. 171 3e-42
BC073740-1|AAH73740.1| 388|Homo sapiens progastricsin (pepsinog... 171 3e-42
AL365205-1|CAI13181.1| 388|Homo sapiens progastricsin (pepsinog... 171 3e-42
J00287-1|AAA98529.1| 388|Homo sapiens PEP protein. 169 9e-42
BC029055-1|AAH29055.1| 388|Homo sapiens pepsinogen 5, group I (... 169 9e-42
M26032-1|AAA60061.1| 388|Homo sapiens pepsinogen A protein. 168 3e-41
X00063-1|CAA24937.1| 300|Homo sapiens protein ( Human kidney mR... 139 1e-32
AK075539-1|BAC11682.1| 423|Homo sapiens protein ( Homo sapiens ... 71 4e-12
BC014453-1|AAH14453.1| 518|Homo sapiens beta-site APP-cleaving ... 71 6e-12
AY358927-1|AAQ89286.1| 518|Homo sapiens BACE2 protein. 71 6e-12
AF212252-1|AAG41783.1| 439|Homo sapiens CDA13 protein. 71 6e-12
AF204944-1|AAF26368.1| 518|Homo sapiens transmembrane aspartic ... 71 6e-12
AF200342-1|AAF17078.1| 518|Homo sapiens aspartyl protease 1 pro... 71 6e-12
AF200192-1|AAF13714.1| 518|Homo sapiens memapsin 1 protein. 71 6e-12
AF188277-1|AAF35836.1| 396|Homo sapiens aspartyl protease protein. 71 6e-12
AF188276-1|AAF35835.1| 468|Homo sapiens aspartyl protease protein. 71 6e-12
AF178532-1|AAF29494.1| 518|Homo sapiens aspartyl protease protein. 71 6e-12
AF117892-1|AAD45240.1| 518|Homo sapiens aspartic-like protease ... 71 6e-12
AF050171-1|AAD45963.1| 518|Homo sapiens aspartyl protease protein. 71 6e-12
DQ007053-1|AAY16982.1| 501|Homo sapiens beta-site APP-cleaving ... 66 1e-10
BC065492-1|AAH65492.1| 501|Homo sapiens beta-site APP-cleaving ... 66 1e-10
AF204943-1|AAF26367.1| 501|Homo sapiens transmembrane aspartic ... 66 1e-10
AF201468-1|AAF18982.1| 501|Homo sapiens APP beta-secretase prot... 66 1e-10
AF200343-1|AAF17079.1| 501|Homo sapiens aspartyl protease 2 pro... 66 1e-10
AF200193-1|AAF13715.1| 488|Homo sapiens memapsin 2 protein. 66 1e-10
AF190725-1|AAF04142.1| 501|Homo sapiens beta-site APP cleaving ... 66 1e-10
AB032975-1|BAA86463.2| 532|Homo sapiens KIAA1149 protein protein. 66 1e-10
BC036084-1|AAH36084.1| 501|Homo sapiens beta-site APP-cleaving ... 64 7e-10
AL365205-2|CAI95135.1| 140|Homo sapiens progastricsin (pepsinog... 62 4e-09
BC042578-1|AAH42578.1| 104|Homo sapiens PGC protein protein. 60 1e-08
AF338816-1|AAK38374.1| 476|Homo sapiens beta-site APP cleaving ... 55 3e-07
AB050436-1|BAB40931.1| 476|Homo sapiens beta-site APP cleaving ... 55 3e-07
AL163285-1|CAB90554.1| 415|Homo sapiens beta-site APP-cleaving ... 54 6e-07
AB177847-1|BAD66825.1| 396|Homo sapiens KIAA1149 splice variant... 42 0.004
AB050438-1|BAB40933.1| 432|Homo sapiens beta-site APP cleaving ... 41 0.006
AF338817-1|AAK38375.1| 457|Homo sapiens beta-site APP cleaving ... 41 0.007
AB050437-1|BAB40932.1| 457|Homo sapiens beta-site APP cleaving ... 41 0.007
AL365205-3|CAM16152.1| 86|Homo sapiens progastricsin (pepsinog... 39 0.029
BC117433-1|AAI17434.1| 463|Homo sapiens coiled-coil domain cont... 36 0.27
BC117431-1|AAI17432.1| 463|Homo sapiens coiled-coil domain cont... 36 0.27
AK057488-1|BAB71508.1| 463|Homo sapiens protein ( Homo sapiens ... 36 0.27
AB089958-1|BAC81826.1| 127|Homo sapiens beta-site APP cleaving ... 36 0.27
M11437-2|AAB59550.1| 644|Homo sapiens kininogen protein. 33 1.5
AK126042-1|BAC86409.1| 265|Homo sapiens protein ( Homo sapiens ... 32 3.4
BC104851-1|AAI04852.1| 147|Homo sapiens LOC283174 protein protein. 31 5.9
BC101691-1|AAI01692.1| 147|Homo sapiens LOC283174 protein protein. 31 5.9
BC030606-1|AAH30606.2| 514|Homo sapiens coiled-coil domain cont... 31 7.8
>X05344-1|CAA28955.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 242 bits (593), Expect = 1e-63
Identities = 129/249 (51%), Positives = 160/249 (64%), Gaps = 23/249 (9%)
Frame = +1
Query: 208 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 354
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 355 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTS 534
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +I C +H+KY+S KS++
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 535 YVANGTQFAIQYGSGSLSGFLSTDDVTV-----------GGLKVRRQTFAEAVSEPGLAF 681
YV NGT F I YGSGSLSG+LS D V+V GG+KV RQ F EA +PG+ F
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITF 190
Query: 682 VAAKFDGILGMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXXS 858
+AAKFDGILGMA+ I+V++V PVFDN++ Q LV Q +FSFYL+RDP A +
Sbjct: 191 IAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFYLSRDPDAQPGGELMLGGT 250
Query: 859 DPAHYRGDL 885
D +Y+G L
Sbjct: 251 DSKYYKGSL 259
>M63138-1|AAA51922.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 242 bits (593), Expect = 1e-63
Identities = 129/249 (51%), Positives = 160/249 (64%), Gaps = 23/249 (9%)
Frame = +1
Query: 208 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 354
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 355 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTS 534
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +I C +H+KY+S KS++
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 535 YVANGTQFAIQYGSGSLSGFLSTDDVTV-----------GGLKVRRQTFAEAVSEPGLAF 681
YV NGT F I YGSGSLSG+LS D V+V GG+KV RQ F EA +PG+ F
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITF 190
Query: 682 VAAKFDGILGMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXXS 858
+AAKFDGILGMA+ I+V++V PVFDN++ Q LV Q +FSFYL+RDP A +
Sbjct: 191 IAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFYLSRDPDAQPGGELMLGGT 250
Query: 859 DPAHYRGDL 885
D +Y+G L
Sbjct: 251 DSKYYKGSL 259
>M11233-1|AAB59529.1| 412|Homo sapiens CTSD protein.
Length = 412
Score = 242 bits (593), Expect = 1e-63
Identities = 129/249 (51%), Positives = 160/249 (64%), Gaps = 23/249 (9%)
Frame = +1
Query: 208 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 354
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 355 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTS 534
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +I C +H+KY+S KS++
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 535 YVANGTQFAIQYGSGSLSGFLSTDDVTV-----------GGLKVRRQTFAEAVSEPGLAF 681
YV NGT F I YGSGSLSG+LS D V+V GG+KV RQ F EA +PG+ F
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITF 190
Query: 682 VAAKFDGILGMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXXS 858
+AAKFDGILGMA+ I+V++V PVFDN++ Q LV Q +FSFYL+RDP A +
Sbjct: 191 IAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFYLSRDPDAQPGGELMLGGT 250
Query: 859 DPAHYRGDL 885
D +Y+G L
Sbjct: 251 DSKYYKGSL 259
>CR456947-1|CAG33228.1| 412|Homo sapiens CTSD protein.
Length = 412
Score = 242 bits (593), Expect = 1e-63
Identities = 129/249 (51%), Positives = 160/249 (64%), Gaps = 23/249 (9%)
Frame = +1
Query: 208 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 354
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 355 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTS 534
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +I C +H+KY+S KS++
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 535 YVANGTQFAIQYGSGSLSGFLSTDDVTV-----------GGLKVRRQTFAEAVSEPGLAF 681
YV NGT F I YGSGSLSG+LS D V+V GG+KV RQ F EA +PG+ F
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITF 190
Query: 682 VAAKFDGILGMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXXS 858
+AAKFDGILGMA+ I+V++V PVFDN++ Q LV Q +FSFYL+RDP A +
Sbjct: 191 IAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFYLSRDPDAQPGGELMLGGT 250
Query: 859 DPAHYRGDL 885
D +Y+G L
Sbjct: 251 DSKYYKGSL 259
>BT020155-1|AAV38957.1| 412|Homo sapiens cathepsin D (lysosomal
aspartyl protease) protein.
Length = 412
Score = 242 bits (593), Expect = 1e-63
Identities = 129/249 (51%), Positives = 160/249 (64%), Gaps = 23/249 (9%)
Frame = +1
Query: 208 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 354
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 355 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTS 534
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +I C +H+KY+S KS++
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 535 YVANGTQFAIQYGSGSLSGFLSTDDVTV-----------GGLKVRRQTFAEAVSEPGLAF 681
YV NGT F I YGSGSLSG+LS D V+V GG+KV RQ F EA +PG+ F
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITF 190
Query: 682 VAAKFDGILGMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXXS 858
+AAKFDGILGMA+ I+V++V PVFDN++ Q LV Q +FSFYL+RDP A +
Sbjct: 191 IAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFYLSRDPDAQPGGELMLGGT 250
Query: 859 DPAHYRGDL 885
D +Y+G L
Sbjct: 251 DSKYYKGSL 259
>BT006910-1|AAP35556.1| 412|Homo sapiens cathepsin D (lysosomal
aspartyl protease) protein.
Length = 412
Score = 242 bits (593), Expect = 1e-63
Identities = 129/249 (51%), Positives = 160/249 (64%), Gaps = 23/249 (9%)
Frame = +1
Query: 208 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 354
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 355 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTS 534
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +I C +H+KY+S KS++
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 535 YVANGTQFAIQYGSGSLSGFLSTDDVTV-----------GGLKVRRQTFAEAVSEPGLAF 681
YV NGT F I YGSGSLSG+LS D V+V GG+KV RQ F EA +PG+ F
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITF 190
Query: 682 VAAKFDGILGMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXXS 858
+AAKFDGILGMA+ I+V++V PVFDN++ Q LV Q +FSFYL+RDP A +
Sbjct: 191 IAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFYLSRDPDAQPGGELMLGGT 250
Query: 859 DPAHYRGDL 885
D +Y+G L
Sbjct: 251 DSKYYKGSL 259
>BC016320-1|AAH16320.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 242 bits (593), Expect = 1e-63
Identities = 129/249 (51%), Positives = 160/249 (64%), Gaps = 23/249 (9%)
Frame = +1
Query: 208 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 354
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 355 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTS 534
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +I C +H+KY+S KS++
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 535 YVANGTQFAIQYGSGSLSGFLSTDDVTV-----------GGLKVRRQTFAEAVSEPGLAF 681
YV NGT F I YGSGSLSG+LS D V+V GG+KV RQ F EA +PG+ F
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITF 190
Query: 682 VAAKFDGILGMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXXS 858
+AAKFDGILGMA+ I+V++V PVFDN++ Q LV Q +FSFYL+RDP A +
Sbjct: 191 IAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFYLSRDPDAQPGGELMLGGT 250
Query: 859 DPAHYRGDL 885
D +Y+G L
Sbjct: 251 DSKYYKGSL 259
>BC017842-1|AAH17842.1| 420|Homo sapiens napsin A aspartic
peptidase protein.
Length = 420
Score = 219 bits (536), Expect = 9e-57
Identities = 109/225 (48%), Positives = 144/225 (64%), Gaps = 6/225 (2%)
Frame = +1
Query: 217 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 381
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRTLNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 382 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTSYVANGTQFA 561
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S+S+ ANGT+FA
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFA 138
Query: 562 IQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDH 741
IQYG+G + G LS D +T+GG+K F EA+ EP L F A FDGILG+ F ++V+
Sbjct: 139 IQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAFAHFDGILGLGFPILSVEG 198
Query: 742 VTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXXSDPAHY 873
V P D +V QGL+ +PVFSFYLNRDP SDPAHY
Sbjct: 199 VRPPMDVLVEQGLLDKPVFSFYLNRDPEEPDGGELVLGGSDPAHY 243
>AF200345-1|AAF17081.1| 420|Homo sapiens aspartyl protease 4
protein.
Length = 420
Score = 219 bits (535), Expect = 1e-56
Identities = 109/225 (48%), Positives = 144/225 (64%), Gaps = 6/225 (2%)
Frame = +1
Query: 217 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 381
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 382 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTSYVANGTQFA 561
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S+S+ ANGT+FA
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFA 138
Query: 562 IQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDH 741
IQYG+G + G LS D +T+GG+K F EA+ EP L F A FDGILG+ F ++V+
Sbjct: 139 IQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAFAHFDGILGLGFPILSVEG 198
Query: 742 VTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXXSDPAHY 873
V P D +V QGL+ +PVFSFYLNRDP SDPAHY
Sbjct: 199 VRPPMDVLVEQGLLDKPVFSFYLNRDPEEPDGGELVLGGSDPAHY 243
>AF098484-1|AAD13215.1| 420|Homo sapiens napsin 1 precursor
protein.
Length = 420
Score = 219 bits (535), Expect = 1e-56
Identities = 109/225 (48%), Positives = 144/225 (64%), Gaps = 6/225 (2%)
Frame = +1
Query: 217 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 381
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 382 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTSYVANGTQFA 561
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S+S+ ANGT+FA
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFA 138
Query: 562 IQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDH 741
IQYG+G + G LS D +T+GG+K F EA+ EP L F A FDGILG+ F ++V+
Sbjct: 139 IQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAFAHFDGILGLGFPILSVEG 198
Query: 742 VTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXXSDPAHY 873
V P D +V QGL+ +PVFSFYLNRDP SDPAHY
Sbjct: 199 VRPPMDVLVEQGLLDKPVFSFYLNRDPEEPDGGELVLGGSDPAHY 243
>AF090386-1|AAD04917.1| 420|Homo sapiens napsin A protein.
Length = 420
Score = 219 bits (535), Expect = 1e-56
Identities = 109/225 (48%), Positives = 144/225 (64%), Gaps = 6/225 (2%)
Frame = +1
Query: 217 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 381
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 382 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTSYVANGTQFA 561
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S+S+ ANGT+FA
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFA 138
Query: 562 IQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDH 741
IQYG+G + G LS D +T+GG+K F EA+ EP L F A FDGILG+ F ++V+
Sbjct: 139 IQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAFAHFDGILGLGFPILSVEG 198
Query: 742 VTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXXSDPAHY 873
V P D +V QGL+ +PVFSFYLNRDP SDPAHY
Sbjct: 199 VRPPMDVLVEQGLLDKPVFSFYLNRDPEEPDGGELVLGGSDPAHY 243
>BC111705-1|AAI11706.1| 464|Homo sapiens NAPSB protein protein.
Length = 464
Score = 201 bits (491), Expect = 2e-51
Identities = 99/218 (45%), Positives = 137/218 (62%), Gaps = 6/218 (2%)
Frame = +1
Query: 238 LYRVPLHRMKTARTHFHEV---GTELELLRLKYDVTGPSPE--PLSNYLDAQYYGVISIG 402
L R+PL ++ R + + G EL +L G P PLS +LDAQY+G I +G
Sbjct: 22 LIRIPLRQVHPGRRTLNLLRGWGKPAELPKLGAPSPGDKPASVPLSKFLDAQYFGEIGLG 81
Query: 403 TPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTSYVANGTQFAIQYGSGS 582
TPPQ+F V FDTGSSNLWVPS++CH+ ++ C H++++ S+S+ +GT+FAIQYG+G
Sbjct: 82 TPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWFHHRFNPNASSSFKPSGTKFAIQYGTGR 141
Query: 583 LSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDN 762
+ G LS D +T+GG+K F EA+ E L F ++ DGILG+ F ++V+ V P D
Sbjct: 142 VDGILSEDKLTIGGIKGASVIFGEALWESSLVFTVSRPDGILGLGFPILSVEGVRPPLDV 201
Query: 763 MVAQGLV-QPVFSFYLNRDPGATTXXXXXXXXSDPAHY 873
+V QGL+ +PVFSFY NRDP SDPAHY
Sbjct: 202 LVEQGLLDKPVFSFYFNRDPEVADGGELVLGGSDPAHY 239
>AF200344-1|AAF17080.1| 450|Homo sapiens aspartyl protease 3
protein.
Length = 450
Score = 201 bits (491), Expect = 2e-51
Identities = 99/218 (45%), Positives = 137/218 (62%), Gaps = 6/218 (2%)
Frame = +1
Query: 238 LYRVPLHRMKTARTHFHEV---GTELELLRLKYDVTGPSPE--PLSNYLDAQYYGVISIG 402
L R+PL ++ R + + G EL +L G P PLS +LDAQY+G I +G
Sbjct: 26 LIRIPLRQVHPGRRTLNLLRGWGKPAELPKLGAPSPGDKPASVPLSKFLDAQYFGEIGLG 85
Query: 403 TPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTSYVANGTQFAIQYGSGS 582
TPPQ+F V FDTGSSNLWVPS++CH+ ++ C H++++ S+S+ +GT+FAIQYG+G
Sbjct: 86 TPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWFHHRFNPNASSSFKPSGTKFAIQYGTGR 145
Query: 583 LSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDN 762
+ G LS D +T+GG+K F EA+ E L F ++ DGILG+ F ++V+ V P D
Sbjct: 146 VDGILSEDKLTIGGIKGASVIFGEALWESSLVFTVSRPDGILGLGFPILSVEGVRPPLDV 205
Query: 763 MVAQGLV-QPVFSFYLNRDPGATTXXXXXXXXSDPAHY 873
+V QGL+ +PVFSFY NRDP SDPAHY
Sbjct: 206 LVEQGLLDKPVFSFYFNRDPEVADGGELVLGGSDPAHY 243
>M10152-1|AAD03461.1| 406|Homo sapiens renin protein.
Length = 406
Score = 193 bits (470), Expect = 9e-49
Identities = 91/179 (50%), Positives = 119/179 (66%), Gaps = 3/179 (1%)
Frame = +1
Query: 355 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTS 534
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC C+ H +D+ S+S
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 535 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGM 714
Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F E P L F+ A+FDG++GM
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPALPFMLAEFDGVVGM 196
Query: 715 AFSTIAVDHVTPVFDNMVAQG-LVQPVFSFYLNRDP--GATTXXXXXXXXSDPAHYRGD 882
F A+ VTP+FDN+++QG L + VFSFY NRD + SDP HY G+
Sbjct: 197 GFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEGN 255
>L00073-1|AAA60363.1| 406|Homo sapiens renin protein.
Length = 406
Score = 193 bits (470), Expect = 9e-49
Identities = 91/179 (50%), Positives = 119/179 (66%), Gaps = 3/179 (1%)
Frame = +1
Query: 355 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTS 534
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC C+ H +D+ S+S
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 535 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGM 714
Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F E P L F+ A+FDG++GM
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPALPFMLAEFDGVVGM 196
Query: 715 AFSTIAVDHVTPVFDNMVAQG-LVQPVFSFYLNRDP--GATTXXXXXXXXSDPAHYRGD 882
F A+ VTP+FDN+++QG L + VFSFY NRD + SDP HY G+
Sbjct: 197 GFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEGN 255
>CR536498-1|CAG38737.1| 406|Homo sapiens REN protein.
Length = 406
Score = 193 bits (470), Expect = 9e-49
Identities = 91/179 (50%), Positives = 119/179 (66%), Gaps = 3/179 (1%)
Frame = +1
Query: 355 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTS 534
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC C+ H +D+ S+S
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 535 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGM 714
Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F E P L F+ A+FDG++GM
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPALPFMLAEFDGVVGM 196
Query: 715 AFSTIAVDHVTPVFDNMVAQG-LVQPVFSFYLNRDP--GATTXXXXXXXXSDPAHYRGD 882
F A+ VTP+FDN+++QG L + VFSFY NRD + SDP HY G+
Sbjct: 197 GFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEGN 255
>BC047752-1|AAH47752.1| 406|Homo sapiens renin protein.
Length = 406
Score = 193 bits (470), Expect = 9e-49
Identities = 91/179 (50%), Positives = 119/179 (66%), Gaps = 3/179 (1%)
Frame = +1
Query: 355 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTS 534
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC C+ H +D+ S+S
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 535 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGM 714
Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F E P L F+ A+FDG++GM
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPALPFMLAEFDGVVGM 196
Query: 715 AFSTIAVDHVTPVFDNMVAQG-LVQPVFSFYLNRDP--GATTXXXXXXXXSDPAHYRGD 882
F A+ VTP+FDN+++QG L + VFSFY NRD + SDP HY G+
Sbjct: 197 GFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEGN 255
>BC033474-1|AAH33474.1| 406|Homo sapiens renin protein.
Length = 406
Score = 193 bits (470), Expect = 9e-49
Identities = 91/179 (50%), Positives = 119/179 (66%), Gaps = 3/179 (1%)
Frame = +1
Query: 355 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTS 534
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC C+ H +D+ S+S
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 535 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGM 714
Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F E P L F+ A+FDG++GM
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPALPFMLAEFDGVVGM 196
Query: 715 AFSTIAVDHVTPVFDNMVAQG-LVQPVFSFYLNRDP--GATTXXXXXXXXSDPAHYRGD 882
F A+ VTP+FDN+++QG L + VFSFY NRD + SDP HY G+
Sbjct: 197 GFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEGN 255
>AL592146-1|CAI16594.1| 406|Homo sapiens renin protein.
Length = 406
Score = 193 bits (470), Expect = 9e-49
Identities = 91/179 (50%), Positives = 119/179 (66%), Gaps = 3/179 (1%)
Frame = +1
Query: 355 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTS 534
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC C+ H +D+ S+S
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 535 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGM 714
Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F E P L F+ A+FDG++GM
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPALPFMLAEFDGVVGM 196
Query: 715 AFSTIAVDHVTPVFDNMVAQG-LVQPVFSFYLNRDP--GATTXXXXXXXXSDPAHYRGD 882
F A+ VTP+FDN+++QG L + VFSFY NRD + SDP HY G+
Sbjct: 197 GFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEGN 255
>AL592114-1|CAH71224.1| 406|Homo sapiens renin protein.
Length = 406
Score = 193 bits (470), Expect = 9e-49
Identities = 91/179 (50%), Positives = 119/179 (66%), Gaps = 3/179 (1%)
Frame = +1
Query: 355 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTS 534
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC C+ H +D+ S+S
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 535 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGM 714
Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F E P L F+ A+FDG++GM
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPALPFMLAEFDGVVGM 196
Query: 715 AFSTIAVDHVTPVFDNMVAQG-LVQPVFSFYLNRDP--GATTXXXXXXXXSDPAHYRGD 882
F A+ VTP+FDN+++QG L + VFSFY NRD + SDP HY G+
Sbjct: 197 GFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEGN 255
>M84424-1|AAA52300.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 192 bits (468), Expect = 2e-48
Identities = 104/240 (43%), Positives = 145/240 (60%), Gaps = 11/240 (4%)
Frame = +1
Query: 199 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 348
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 349 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKS 528
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ C H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 529 TSYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGIL 708
++Y G F+IQYG+GSLSG + D V+V GL V Q F E+V+EPG FV A+FDGIL
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGIL 185
Query: 709 GMAFSTIAVDHVTPVFDNMVAQGLVQ-PVFSFYLNRDPGATTXXXXXXXXSDPAHYRGDL 885
G+ + ++AV VTPVFDNM+AQ LV P+FS Y++ +P D +H+ G L
Sbjct: 186 GLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSL 245
>M26901-1|AAA60364.1| 403|Homo sapiens renin protein.
Length = 403
Score = 192 bits (468), Expect = 2e-48
Identities = 90/177 (50%), Positives = 119/177 (67%), Gaps = 1/177 (0%)
Frame = +1
Query: 355 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTS 534
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC C+ H +D+ S+S
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 535 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGM 714
Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F E P L F+ A+FDG++GM
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPALPFMLAQFDGVVGM 196
Query: 715 AFSTIAVDHVTPVFDNMVAQG-LVQPVFSFYLNRDPGATTXXXXXXXXSDPAHYRGD 882
F A+ VTP+FDN+++QG L + VFSFY NR+ + SDP HY G+
Sbjct: 197 GFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRN-SQSLGGQIVLGGSDPQHYEGN 252
>J05036-1|AAA52130.1| 396|Homo sapiens CTSE protein.
Length = 396
Score = 192 bits (468), Expect = 2e-48
Identities = 104/240 (43%), Positives = 145/240 (60%), Gaps = 11/240 (4%)
Frame = +1
Query: 199 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 348
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 349 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKS 528
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ C H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 529 TSYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGIL 708
++Y G F+IQYG+GSLSG + D V+V GL V Q F E+V+EPG FV A+FDGIL
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGIL 185
Query: 709 GMAFSTIAVDHVTPVFDNMVAQGLVQ-PVFSFYLNRDPGATTXXXXXXXXSDPAHYRGDL 885
G+ + ++AV VTPVFDNM+AQ LV P+FS Y++ +P D +H+ G L
Sbjct: 186 GLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSL 245
>BX571818-5|CAH73265.1| 363|Homo sapiens cathepsin E protein.
Length = 363
Score = 192 bits (468), Expect = 2e-48
Identities = 104/240 (43%), Positives = 145/240 (60%), Gaps = 11/240 (4%)
Frame = +1
Query: 199 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 348
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 349 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKS 528
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ C H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 529 TSYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGIL 708
++Y G F+IQYG+GSLSG + D V+V GL V Q F E+V+EPG FV A+FDGIL
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGIL 185
Query: 709 GMAFSTIAVDHVTPVFDNMVAQGLVQ-PVFSFYLNRDPGATTXXXXXXXXSDPAHYRGDL 885
G+ + ++AV VTPVFDNM+AQ LV P+FS Y++ +P D +H+ G L
Sbjct: 186 GLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSL 245
>BX571818-4|CAH73264.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 192 bits (468), Expect = 2e-48
Identities = 104/240 (43%), Positives = 145/240 (60%), Gaps = 11/240 (4%)
Frame = +1
Query: 199 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 348
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 349 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKS 528
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ C H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 529 TSYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGIL 708
++Y G F+IQYG+GSLSG + D V+V GL V Q F E+V+EPG FV A+FDGIL
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGIL 185
Query: 709 GMAFSTIAVDHVTPVFDNMVAQGLVQ-PVFSFYLNRDPGATTXXXXXXXXSDPAHYRGDL 885
G+ + ++AV VTPVFDNM+AQ LV P+FS Y++ +P D +H+ G L
Sbjct: 186 GLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSL 245
>BC042537-1|AAH42537.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 192 bits (468), Expect = 2e-48
Identities = 104/240 (43%), Positives = 145/240 (60%), Gaps = 11/240 (4%)
Frame = +1
Query: 199 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 348
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 349 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKS 528
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ C H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 529 TSYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGIL 708
++Y G F+IQYG+GSLSG + D V+V GL V Q F E+V+EPG FV A+FDGIL
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGIL 185
Query: 709 GMAFSTIAVDHVTPVFDNMVAQGLVQ-PVFSFYLNRDPGATTXXXXXXXXSDPAHYRGDL 885
G+ + ++AV VTPVFDNM+AQ LV P+FS Y++ +P D +H+ G L
Sbjct: 186 GLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSL 245
>AY436324-1|AAR03502.1| 403|Homo sapiens renin protein.
Length = 403
Score = 192 bits (468), Expect = 2e-48
Identities = 90/177 (50%), Positives = 119/177 (67%), Gaps = 1/177 (0%)
Frame = +1
Query: 355 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTS 534
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC C+ H +D+ S+S
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 535 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGM 714
Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F E P L F+ A+FDG++GM
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPALPFMLAEFDGVVGM 196
Query: 715 AFSTIAVDHVTPVFDNMVAQG-LVQPVFSFYLNRDPGATTXXXXXXXXSDPAHYRGD 882
F A+ VTP+FDN+++QG L + VFSFY NR+ + SDP HY G+
Sbjct: 197 GFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRN-SQSLGGQIVLGGSDPQHYEGN 252
>AJ250717-1|CAB82850.1| 396|Homo sapiens procathepsin E protein.
Length = 396
Score = 192 bits (468), Expect = 2e-48
Identities = 104/240 (43%), Positives = 145/240 (60%), Gaps = 11/240 (4%)
Frame = +1
Query: 199 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 348
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 349 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKS 528
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ C H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 529 TSYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGIL 708
++Y G F+IQYG+GSLSG + D V+V GL V Q F E+V+EPG FV A+FDGIL
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGIL 185
Query: 709 GMAFSTIAVDHVTPVFDNMVAQGLVQ-PVFSFYLNRDPGATTXXXXXXXXSDPAHYRGDL 885
G+ + ++AV VTPVFDNM+AQ LV P+FS Y++ +P D +H+ G L
Sbjct: 186 GLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSL 245
>AJ250716-1|CAB82849.1| 363|Homo sapiens cathepsin E, alternative
protein.
Length = 363
Score = 192 bits (468), Expect = 2e-48
Identities = 104/240 (43%), Positives = 145/240 (60%), Gaps = 11/240 (4%)
Frame = +1
Query: 199 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 348
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 349 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKS 528
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ C H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 529 TSYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGIL 708
++Y G F+IQYG+GSLSG + D V+V GL V Q F E+V+EPG FV A+FDGIL
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGIL 185
Query: 709 GMAFSTIAVDHVTPVFDNMVAQGLVQ-PVFSFYLNRDPGATTXXXXXXXXSDPAHYRGDL 885
G+ + ++AV VTPVFDNM+AQ LV P+FS Y++ +P D +H+ G L
Sbjct: 186 GLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSL 245
>U75272-1|AAB18273.1| 388|Homo sapiens gastricsin protein.
Length = 388
Score = 171 bits (416), Expect = 3e-42
Identities = 92/208 (44%), Positives = 129/208 (62%), Gaps = 10/208 (4%)
Frame = +1
Query: 235 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 387
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 388 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTSYVANGTQFAIQ 567
ISIGTPPQ+F V+FDTGSSNLWVPS C + C H++++ +S++Y NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 568 YGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVT 747
YGSGSL+GF D +TV ++V Q F + +EPG FV A+FDGI+G+A+ ++VD T
Sbjct: 134 YGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEAT 193
Query: 748 PVFDNMVAQG-LVQPVFSFYLNRDPGAT 828
MV +G L PVFS YL+ G++
Sbjct: 194 TAMQGMVQEGALTSPVFSVYLSNQQGSS 221
>M23077-1|AAA60063.1| 388|Homo sapiens pepsinogen C protein.
Length = 388
Score = 171 bits (416), Expect = 3e-42
Identities = 92/208 (44%), Positives = 129/208 (62%), Gaps = 10/208 (4%)
Frame = +1
Query: 235 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 387
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 388 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTSYVANGTQFAIQ 567
ISIGTPPQ+F V+FDTGSSNLWVPS C + C H++++ +S++Y NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 568 YGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVT 747
YGSGSL+GF D +TV ++V Q F + +EPG FV A+FDGI+G+A+ ++VD T
Sbjct: 134 YGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEAT 193
Query: 748 PVFDNMVAQG-LVQPVFSFYLNRDPGAT 828
MV +G L PVFS YL+ G++
Sbjct: 194 TAMQGMVQEGALTSPVFSVYLSNQQGSS 221
>M18667-1|AAA60062.1| 385|Homo sapiens pepsinogen protein.
Length = 385
Score = 171 bits (416), Expect = 3e-42
Identities = 92/208 (44%), Positives = 129/208 (62%), Gaps = 10/208 (4%)
Frame = +1
Query: 235 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 387
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 14 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 72
Query: 388 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTSYVANGTQFAIQ 567
ISIGTPPQ+F V+FDTGSSNLWVPS C + C H++++ +S++Y NG F++Q
Sbjct: 73 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 130
Query: 568 YGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVT 747
YGSGSL+GF D +TV ++V Q F + +EPG FV A+FDGI+G+A+ ++VD T
Sbjct: 131 YGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEAT 190
Query: 748 PVFDNMVAQG-LVQPVFSFYLNRDPGAT 828
MV +G L PVFS YL+ G++
Sbjct: 191 TAMQGMVQEGALTSPVFSVYLSNQQGSS 218
>J04443-1|AAA60074.1| 388|Homo sapiens pepsinogen protein.
Length = 388
Score = 171 bits (416), Expect = 3e-42
Identities = 92/208 (44%), Positives = 129/208 (62%), Gaps = 10/208 (4%)
Frame = +1
Query: 235 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 387
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 388 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTSYVANGTQFAIQ 567
ISIGTPPQ+F V+FDTGSSNLWVPS C + C H++++ +S++Y NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 568 YGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVT 747
YGSGSL+GF D +TV ++V Q F + +EPG FV A+FDGI+G+A+ ++VD T
Sbjct: 134 YGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEAT 193
Query: 748 PVFDNMVAQG-LVQPVFSFYLNRDPGAT 828
MV +G L PVFS YL+ G++
Sbjct: 194 TAMQGMVQEGALTSPVFSVYLSNQQGSS 221
>BC073740-1|AAH73740.1| 388|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 388
Score = 171 bits (416), Expect = 3e-42
Identities = 92/208 (44%), Positives = 129/208 (62%), Gaps = 10/208 (4%)
Frame = +1
Query: 235 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 387
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 388 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTSYVANGTQFAIQ 567
ISIGTPPQ+F V+FDTGSSNLWVPS C + C H++++ +S++Y NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 568 YGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVT 747
YGSGSL+GF D +TV ++V Q F + +EPG FV A+FDGI+G+A+ ++VD T
Sbjct: 134 YGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEAT 193
Query: 748 PVFDNMVAQG-LVQPVFSFYLNRDPGAT 828
MV +G L PVFS YL+ G++
Sbjct: 194 TAMQGMVQEGALTSPVFSVYLSNQQGSS 221
>AL365205-1|CAI13181.1| 388|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 388
Score = 171 bits (416), Expect = 3e-42
Identities = 92/208 (44%), Positives = 129/208 (62%), Gaps = 10/208 (4%)
Frame = +1
Query: 235 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 387
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 388 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTSYVANGTQFAIQ 567
ISIGTPPQ+F V+FDTGSSNLWVPS C + C H++++ +S++Y NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 568 YGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVT 747
YGSGSL+GF D +TV ++V Q F + +EPG FV A+FDGI+G+A+ ++VD T
Sbjct: 134 YGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEAT 193
Query: 748 PVFDNMVAQG-LVQPVFSFYLNRDPGAT 828
MV +G L PVFS YL+ G++
Sbjct: 194 TAMQGMVQEGALTSPVFSVYLSNQQGSS 221
>J00287-1|AAA98529.1| 388|Homo sapiens PEP protein.
Length = 388
Score = 169 bits (412), Expect = 9e-42
Identities = 99/242 (40%), Positives = 135/242 (55%), Gaps = 13/242 (5%)
Frame = +1
Query: 199 LFFLALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP--- 348
L L L+A S +Y+VPL R K+ R E G + L+ KY +P
Sbjct: 4 LLLLGLVALSECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAPTLV 63
Query: 349 --EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSR 522
+PL NYLD +Y+G I IGTP Q F VVFDTGSSNLWVPS C +++ C HN+++
Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYC--SSLACTNHNRFNPE 121
Query: 523 KSTSYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDG 702
S++Y + +I YG+GS++G L D V VGG+ Q F + +EPG A FDG
Sbjct: 122 DSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDG 181
Query: 703 ILGMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXXSDPAHYRG 879
ILG+A+ +I+ TPVFDN+ QGLV Q +FS YL+ D + D ++Y G
Sbjct: 182 ILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSADD--QSGSVVIFGGIDSSYYTG 239
Query: 880 DL 885
L
Sbjct: 240 SL 241
>BC029055-1|AAH29055.1| 388|Homo sapiens pepsinogen 5, group I
(pepsinogen A) protein.
Length = 388
Score = 169 bits (412), Expect = 9e-42
Identities = 99/242 (40%), Positives = 135/242 (55%), Gaps = 13/242 (5%)
Frame = +1
Query: 199 LFFLALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP--- 348
L L L+A S +Y+VPL R K+ R E G + L+ KY +P
Sbjct: 4 LLLLGLVALSECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAPTLV 63
Query: 349 --EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSR 522
+PL NYLD +Y+G I IGTP Q F VVFDTGSSNLWVPS C +++ C HN+++
Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYC--SSLACTNHNRFNPE 121
Query: 523 KSTSYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDG 702
S++Y + +I YG+GS++G L D V VGG+ Q F + +EPG A FDG
Sbjct: 122 DSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDG 181
Query: 703 ILGMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXXSDPAHYRG 879
ILG+A+ +I+ TPVFDN+ QGLV Q +FS YL+ D + D ++Y G
Sbjct: 182 ILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSADD--KSGSVVIFGGIDSSYYTG 239
Query: 880 DL 885
L
Sbjct: 240 SL 241
>M26032-1|AAA60061.1| 388|Homo sapiens pepsinogen A protein.
Length = 388
Score = 168 bits (408), Expect = 3e-41
Identities = 98/242 (40%), Positives = 135/242 (55%), Gaps = 13/242 (5%)
Frame = +1
Query: 199 LFFLALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP--- 348
L L L+A S +Y+VPL R K+ R E G + L+ KY +P
Sbjct: 4 LLLLGLVALSECIMYKVPLIRKKSFRRTLSERGLLKDFLKKHNLNPARKYFPQWKAPTLV 63
Query: 349 --EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSR 522
+PL NYLD +Y+G I IGTP Q F V+FDTGSSNLWVPS C +++ C HN+++
Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVLFDTGSSNLWVPSVYC--SSLACTNHNRFNPE 121
Query: 523 KSTSYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDG 702
S++Y + +I YG+GS++G L D V VGG+ Q F + +EPG A FDG
Sbjct: 122 DSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDG 181
Query: 703 ILGMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXXSDPAHYRG 879
ILG+A+ +I+ TPVFDN+ QGLV Q +FS YL+ D + D ++Y G
Sbjct: 182 ILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSADD--QSGSVVIFGGIDSSYYTG 239
Query: 880 DL 885
L
Sbjct: 240 SL 241
>X00063-1|CAA24937.1| 300|Homo sapiens protein ( Human kidney mRNA
fragment for renin (aa 105-401). ).
Length = 300
Score = 139 bits (336), Expect = 1e-32
Identities = 67/149 (44%), Positives = 92/149 (61%), Gaps = 3/149 (2%)
Frame = +1
Query: 445 SNLWVPSKKCHYTNITCLLHNKYDSRKSTSYVANGTQFAIQYGSGSLSGFLSTDDVTVGG 624
SN+WVPS KC C+ H +D+ S+SY NGT+ ++Y +G++SGFLS D +TVGG
Sbjct: 1 SNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGG 60
Query: 625 LKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQG-LVQPVFSF 801
+ V Q F E P L F+ A+FDG++GM F A+ VTP+FDN+++QG L + VFSF
Sbjct: 61 ITV-TQMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSF 119
Query: 802 YLNRDP--GATTXXXXXXXXSDPAHYRGD 882
Y NRD + SDP HY G+
Sbjct: 120 YYNRDSENSQSLGGQIVLGGSDPQHYEGN 148
>AK075539-1|BAC11682.1| 423|Homo sapiens protein ( Homo sapiens
cDNA PSEC0239 fis, clone OVARC1000363, highly similar to
Homo sapiens aspartyl protease mRNA. ).
Length = 423
Score = 71.3 bits (167), Expect = 4e-12
Identities = 51/173 (29%), Positives = 84/173 (48%), Gaps = 10/173 (5%)
Frame = +1
Query: 397 IGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTSYVANGTQFAIQYGS 576
IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G ++Y
Sbjct: 3 IGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDVTVKYTQ 56
Query: 577 GSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFSTIA--VDHV 744
GS +GF+ D VT+ G + E G F+ +++GILG+A++T+A +
Sbjct: 57 GSWTGFVGEDLVTIPKGFNTSFLVNIATIFESGNFFLPGIQWNGILGLAYATLAKPSSSL 116
Query: 745 TPVFDNMVAQGLVQPVFSFYLNRDPGATTXXXXXXXXS------DPAHYRGDL 885
FD++V Q + VFS + R G S +P+ Y+GD+
Sbjct: 117 ETFFDSLVTQANIPNVFSMQM-RGAGLPVAGSGTNGGSLVLGGIEPSLYKGDI 168
>BC014453-1|AAH14453.1| 518|Homo sapiens beta-site APP-cleaving
enzyme 2 protein.
Length = 518
Score = 70.9 bits (166), Expect = 6e-12
Identities = 46/147 (31%), Positives = 75/147 (51%), Gaps = 4/147 (2%)
Frame = +1
Query: 379 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTSYVANGTQF 558
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 559 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFSTIA 732
++Y GS +GF+ D VT+ G + E F+ K++GILG+A++T+A
Sbjct: 146 TVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLA 205
Query: 733 --VDHVTPVFDNMVAQGLVQPVFSFYL 807
+ FD++V Q + VFS +
Sbjct: 206 KPSSSLETFFDSLVTQANIPNVFSMQM 232
>AY358927-1|AAQ89286.1| 518|Homo sapiens BACE2 protein.
Length = 518
Score = 70.9 bits (166), Expect = 6e-12
Identities = 46/147 (31%), Positives = 75/147 (51%), Gaps = 4/147 (2%)
Frame = +1
Query: 379 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTSYVANGTQF 558
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 559 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFSTIA 732
++Y GS +GF+ D VT+ G + E F+ K++GILG+A++T+A
Sbjct: 146 TVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLA 205
Query: 733 --VDHVTPVFDNMVAQGLVQPVFSFYL 807
+ FD++V Q + VFS +
Sbjct: 206 KPSSSLETFFDSLVTQANIPNVFSMQM 232
>AF212252-1|AAG41783.1| 439|Homo sapiens CDA13 protein.
Length = 439
Score = 70.9 bits (166), Expect = 6e-12
Identities = 46/147 (31%), Positives = 75/147 (51%), Gaps = 4/147 (2%)
Frame = +1
Query: 379 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTSYVANGTQF 558
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 13 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 66
Query: 559 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFSTIA 732
++Y GS +GF+ D VT+ G + E F+ K++GILG+A++T+A
Sbjct: 67 TVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLA 126
Query: 733 --VDHVTPVFDNMVAQGLVQPVFSFYL 807
+ FD++V Q + VFS +
Sbjct: 127 KPSSSLETFFDSLVTQANIPNVFSMQM 153
>AF204944-1|AAF26368.1| 518|Homo sapiens transmembrane aspartic
proteinase Asp 1 protein.
Length = 518
Score = 70.9 bits (166), Expect = 6e-12
Identities = 46/147 (31%), Positives = 75/147 (51%), Gaps = 4/147 (2%)
Frame = +1
Query: 379 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTSYVANGTQF 558
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 559 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFSTIA 732
++Y GS +GF+ D VT+ G + E F+ K++GILG+A++T+A
Sbjct: 146 TVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLA 205
Query: 733 --VDHVTPVFDNMVAQGLVQPVFSFYL 807
+ FD++V Q + VFS +
Sbjct: 206 KPSSSLETFFDSLVTQANIPNVFSMQM 232
>AF200342-1|AAF17078.1| 518|Homo sapiens aspartyl protease 1
protein.
Length = 518
Score = 70.9 bits (166), Expect = 6e-12
Identities = 46/147 (31%), Positives = 75/147 (51%), Gaps = 4/147 (2%)
Frame = +1
Query: 379 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTSYVANGTQF 558
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 559 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFSTIA 732
++Y GS +GF+ D VT+ G + E F+ K++GILG+A++T+A
Sbjct: 146 TVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLA 205
Query: 733 --VDHVTPVFDNMVAQGLVQPVFSFYL 807
+ FD++V Q + VFS +
Sbjct: 206 KPSSSLETFFDSLVTQANIPNVFSMQM 232
>AF200192-1|AAF13714.1| 518|Homo sapiens memapsin 1 protein.
Length = 518
Score = 70.9 bits (166), Expect = 6e-12
Identities = 46/147 (31%), Positives = 75/147 (51%), Gaps = 4/147 (2%)
Frame = +1
Query: 379 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTSYVANGTQF 558
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 559 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFSTIA 732
++Y GS +GF+ D VT+ G + E F+ K++GILG+A++T+A
Sbjct: 146 TVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLA 205
Query: 733 --VDHVTPVFDNMVAQGLVQPVFSFYL 807
+ FD++V Q + VFS +
Sbjct: 206 KPSSSLETFFDSLVTQANIPNVFSMQM 232
>AF188277-1|AAF35836.1| 396|Homo sapiens aspartyl protease protein.
Length = 396
Score = 70.9 bits (166), Expect = 6e-12
Identities = 46/147 (31%), Positives = 75/147 (51%), Gaps = 4/147 (2%)
Frame = +1
Query: 379 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTSYVANGTQF 558
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 559 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFSTIA 732
++Y GS +GF+ D VT+ G + E F+ K++GILG+A++T+A
Sbjct: 146 TVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLA 205
Query: 733 --VDHVTPVFDNMVAQGLVQPVFSFYL 807
+ FD++V Q + VFS +
Sbjct: 206 KPSSSLETFFDSLVTQANIPNVFSMQM 232
>AF188276-1|AAF35835.1| 468|Homo sapiens aspartyl protease protein.
Length = 468
Score = 70.9 bits (166), Expect = 6e-12
Identities = 46/147 (31%), Positives = 75/147 (51%), Gaps = 4/147 (2%)
Frame = +1
Query: 379 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTSYVANGTQF 558
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 559 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFSTIA 732
++Y GS +GF+ D VT+ G + E F+ K++GILG+A++T+A
Sbjct: 146 TVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLA 205
Query: 733 --VDHVTPVFDNMVAQGLVQPVFSFYL 807
+ FD++V Q + VFS +
Sbjct: 206 KPSSSLETFFDSLVTQANIPNVFSMQM 232
>AF178532-1|AAF29494.1| 518|Homo sapiens aspartyl protease protein.
Length = 518
Score = 70.9 bits (166), Expect = 6e-12
Identities = 46/147 (31%), Positives = 75/147 (51%), Gaps = 4/147 (2%)
Frame = +1
Query: 379 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTSYVANGTQF 558
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 559 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFSTIA 732
++Y GS +GF+ D VT+ G + E F+ K++GILG+A++T+A
Sbjct: 146 TVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLA 205
Query: 733 --VDHVTPVFDNMVAQGLVQPVFSFYL 807
+ FD++V Q + VFS +
Sbjct: 206 KPSSSLETFFDSLVTQANIPNVFSMQM 232
>AF117892-1|AAD45240.1| 518|Homo sapiens aspartic-like protease
protein.
Length = 518
Score = 70.9 bits (166), Expect = 6e-12
Identities = 46/147 (31%), Positives = 75/147 (51%), Gaps = 4/147 (2%)
Frame = +1
Query: 379 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTSYVANGTQF 558
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 559 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFSTIA 732
++Y GS +GF+ D VT+ G + E F+ K++GILG+A++T+A
Sbjct: 146 TVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLA 205
Query: 733 --VDHVTPVFDNMVAQGLVQPVFSFYL 807
+ FD++V Q + VFS +
Sbjct: 206 KPSSSLETFFDSLVTQANIPNVFSMQM 232
>AF050171-1|AAD45963.1| 518|Homo sapiens aspartyl protease protein.
Length = 518
Score = 70.9 bits (166), Expect = 6e-12
Identities = 46/147 (31%), Positives = 75/147 (51%), Gaps = 4/147 (2%)
Frame = +1
Query: 379 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTSYVANGTQF 558
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 559 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFSTIA 732
++Y GS +GF+ D VT+ G + E F+ K++GILG+A++T+A
Sbjct: 146 TVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLA 205
Query: 733 --VDHVTPVFDNMVAQGLVQPVFSFYL 807
+ FD++V Q + VFS +
Sbjct: 206 KPSSSLETFFDSLVTQANIPNVFSMQM 232
>DQ007053-1|AAY16982.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 66.5 bits (155), Expect = 1e-10
Identities = 47/147 (31%), Positives = 76/147 (51%), Gaps = 4/147 (2%)
Frame = +1
Query: 379 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTSYVANGTQF 558
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 559 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFSTIA 732
+ Y G G L TD V++ G V + A++E F+ + ++GILG+A++ IA
Sbjct: 129 YVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIA 188
Query: 733 --VDHVTPVFDNMVAQGLVQPVFSFYL 807
D + P FD++V Q V +FS L
Sbjct: 189 RPDDSLEPFFDSLVKQTHVPNLFSLQL 215
>BC065492-1|AAH65492.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 66.5 bits (155), Expect = 1e-10
Identities = 47/147 (31%), Positives = 76/147 (51%), Gaps = 4/147 (2%)
Frame = +1
Query: 379 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTSYVANGTQF 558
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 559 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFSTIA 732
+ Y G G L TD V++ G V + A++E F+ + ++GILG+A++ IA
Sbjct: 129 YVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIA 188
Query: 733 --VDHVTPVFDNMVAQGLVQPVFSFYL 807
D + P FD++V Q V +FS L
Sbjct: 189 RPDDSLEPFFDSLVKQTHVPNLFSLQL 215
>AF204943-1|AAF26367.1| 501|Homo sapiens transmembrane aspartic
proteinase Asp 2 protein.
Length = 501
Score = 66.5 bits (155), Expect = 1e-10
Identities = 47/147 (31%), Positives = 76/147 (51%), Gaps = 4/147 (2%)
Frame = +1
Query: 379 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTSYVANGTQF 558
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 559 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFSTIA 732
+ Y G G L TD V++ G V + A++E F+ + ++GILG+A++ IA
Sbjct: 129 YVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIA 188
Query: 733 --VDHVTPVFDNMVAQGLVQPVFSFYL 807
D + P FD++V Q V +FS L
Sbjct: 189 RPDDSLEPFFDSLVKQTHVPNLFSLQL 215
>AF201468-1|AAF18982.1| 501|Homo sapiens APP beta-secretase
protein.
Length = 501
Score = 66.5 bits (155), Expect = 1e-10
Identities = 47/147 (31%), Positives = 76/147 (51%), Gaps = 4/147 (2%)
Frame = +1
Query: 379 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTSYVANGTQF 558
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 559 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFSTIA 732
+ Y G G L TD V++ G V + A++E F+ + ++GILG+A++ IA
Sbjct: 129 YVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIA 188
Query: 733 --VDHVTPVFDNMVAQGLVQPVFSFYL 807
D + P FD++V Q V +FS L
Sbjct: 189 RPDDSLEPFFDSLVKQTHVPNLFSLQL 215
>AF200343-1|AAF17079.1| 501|Homo sapiens aspartyl protease 2
protein.
Length = 501
Score = 66.5 bits (155), Expect = 1e-10
Identities = 47/147 (31%), Positives = 76/147 (51%), Gaps = 4/147 (2%)
Frame = +1
Query: 379 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTSYVANGTQF 558
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 559 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFSTIA 732
+ Y G G L TD V++ G V + A++E F+ + ++GILG+A++ IA
Sbjct: 129 YVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIA 188
Query: 733 --VDHVTPVFDNMVAQGLVQPVFSFYL 807
D + P FD++V Q V +FS L
Sbjct: 189 RPDDSLEPFFDSLVKQTHVPNLFSLQL 215
>AF200193-1|AAF13715.1| 488|Homo sapiens memapsin 2 protein.
Length = 488
Score = 66.5 bits (155), Expect = 1e-10
Identities = 47/147 (31%), Positives = 76/147 (51%), Gaps = 4/147 (2%)
Frame = +1
Query: 379 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTSYVANGTQF 558
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 62 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 115
Query: 559 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFSTIA 732
+ Y G G L TD V++ G V + A++E F+ + ++GILG+A++ IA
Sbjct: 116 YVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIA 175
Query: 733 --VDHVTPVFDNMVAQGLVQPVFSFYL 807
D + P FD++V Q V +FS L
Sbjct: 176 RPDDSLEPFFDSLVKQTHVPNLFSLQL 202
>AF190725-1|AAF04142.1| 501|Homo sapiens beta-site APP cleaving
enzyme protein.
Length = 501
Score = 66.5 bits (155), Expect = 1e-10
Identities = 47/147 (31%), Positives = 76/147 (51%), Gaps = 4/147 (2%)
Frame = +1
Query: 379 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTSYVANGTQF 558
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 559 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFSTIA 732
+ Y G G L TD V++ G V + A++E F+ + ++GILG+A++ IA
Sbjct: 129 YVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIA 188
Query: 733 --VDHVTPVFDNMVAQGLVQPVFSFYL 807
D + P FD++V Q V +FS L
Sbjct: 189 RPDDSLEPFFDSLVKQTHVPNLFSLQL 215
>AB032975-1|BAA86463.2| 532|Homo sapiens KIAA1149 protein protein.
Length = 532
Score = 66.5 bits (155), Expect = 1e-10
Identities = 47/147 (31%), Positives = 76/147 (51%), Gaps = 4/147 (2%)
Frame = +1
Query: 379 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTSYVANGTQF 558
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 106 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 159
Query: 559 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFSTIA 732
+ Y G G L TD V++ G V + A++E F+ + ++GILG+A++ IA
Sbjct: 160 YVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIA 219
Query: 733 --VDHVTPVFDNMVAQGLVQPVFSFYL 807
D + P FD++V Q V +FS L
Sbjct: 220 RPDDSLEPFFDSLVKQTHVPNLFSLQL 246
>BC036084-1|AAH36084.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 64.1 bits (149), Expect = 7e-10
Identities = 46/147 (31%), Positives = 75/147 (51%), Gaps = 4/147 (2%)
Frame = +1
Query: 379 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTSYVANGTQF 558
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + ++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLFSTYRDLRKGV 128
Query: 559 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFSTIA 732
+ Y G G L TD V++ G V + A++E F+ + ++GILG+A++ IA
Sbjct: 129 YVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIA 188
Query: 733 --VDHVTPVFDNMVAQGLVQPVFSFYL 807
D + P FD++V Q V +FS L
Sbjct: 189 RPDDSLEPFFDSLVKQTHVPNLFSLQL 215
>AL365205-2|CAI95135.1| 140|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 140
Score = 61.7 bits (143), Expect = 4e-09
Identities = 30/70 (42%), Positives = 42/70 (60%), Gaps = 1/70 (1%)
Frame = +1
Query: 616 VGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQG-LVQPV 792
V ++V Q F + +EPG FV A+FDGI+G+A+ ++VD T MV +G L PV
Sbjct: 71 VQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEATTAMQGMVQEGALTSPV 130
Query: 793 FSFYLNRDPG 822
FS YL+ G
Sbjct: 131 FSVYLSNQQG 140
>BC042578-1|AAH42578.1| 104|Homo sapiens PGC protein protein.
Length = 104
Score = 60.1 bits (139), Expect = 1e-08
Identities = 38/82 (46%), Positives = 49/82 (59%), Gaps = 9/82 (10%)
Frame = +1
Query: 235 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 387
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 388 VISIGTPPQSFKVVFDTGSSNL 453
ISIGTPPQ+F V+FDTGSS L
Sbjct: 76 EISIGTPPQNFLVLFDTGSSPL 97
>AF338816-1|AAK38374.1| 476|Homo sapiens beta-site APP cleaving
enzyme type B protein.
Length = 476
Score = 55.2 bits (127), Expect = 3e-07
Identities = 37/120 (30%), Positives = 62/120 (51%), Gaps = 2/120 (1%)
Frame = +1
Query: 379 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTSYVANGTQF 558
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 559 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFSTIA 732
+ Y G G L TD V++ G V + A++E F+ + ++GILG+A++ IA
Sbjct: 129 YVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIA 188
>AB050436-1|BAB40931.1| 476|Homo sapiens beta-site APP cleaving
enzyme I-476 protein.
Length = 476
Score = 55.2 bits (127), Expect = 3e-07
Identities = 37/120 (30%), Positives = 62/120 (51%), Gaps = 2/120 (1%)
Frame = +1
Query: 379 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTSYVANGTQF 558
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 559 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFSTIA 732
+ Y G G L TD V++ G V + A++E F+ + ++GILG+A++ IA
Sbjct: 129 YVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIA 188
>AL163285-1|CAB90554.1| 415|Homo sapiens beta-site APP-cleaving
enzyme 2, EC 3.4.23. protein.
Length = 415
Score = 54.4 bits (125), Expect = 6e-07
Identities = 38/133 (28%), Positives = 66/133 (49%), Gaps = 4/133 (3%)
Frame = +1
Query: 421 KVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTSYVANGTQFAIQYGSGSLSGFLS 600
+++ DTGSSN V Y + +D+ +S++Y + G ++Y GS +GF+
Sbjct: 3 QILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDVTVKYTQGSWTGFVG 56
Query: 601 TDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFSTIA--VDHVTPVFDNMV 768
D VT+ G + E F+ K++GILG+A++T+A + FD++V
Sbjct: 57 EDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLV 116
Query: 769 AQGLVQPVFSFYL 807
Q + VFS +
Sbjct: 117 TQANIPNVFSMQM 129
>AB177847-1|BAD66825.1| 396|Homo sapiens KIAA1149 splice variant 1
protein.
Length = 396
Score = 41.5 bits (93), Expect = 0.004
Identities = 29/86 (33%), Positives = 46/86 (53%), Gaps = 4/86 (4%)
Frame = +1
Query: 562 IQYGSGSLSGFLSTDDVTVG-GLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFSTIA- 732
+ Y G G L TD V++ G V + A++E F+ + ++GILG+A++ IA
Sbjct: 25 VPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIAR 84
Query: 733 -VDHVTPVFDNMVAQGLVQPVFSFYL 807
D + P FD++V Q V +FS L
Sbjct: 85 PDDSLEPFFDSLVKQTHVPNLFSLQL 110
>AB050438-1|BAB40933.1| 432|Homo sapiens beta-site APP cleaving
enzyme I-432 protein.
Length = 432
Score = 41.1 bits (92), Expect = 0.006
Identities = 26/94 (27%), Positives = 43/94 (45%)
Frame = +1
Query: 379 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTSYVANGTQF 558
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 559 AIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAV 660
+ Y G G L TD + G + + +V
Sbjct: 129 YVPYTQGKWEGELGTDLLCGAGFPLNQSEVLASV 162
>AF338817-1|AAK38375.1| 457|Homo sapiens beta-site APP cleaving
enzyme type C protein.
Length = 457
Score = 40.7 bits (91), Expect = 0.007
Identities = 24/76 (31%), Positives = 37/76 (48%)
Frame = +1
Query: 379 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTSYVANGTQF 558
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 559 AIQYGSGSLSGFLSTD 606
+ Y G G L TD
Sbjct: 129 YVPYTQGKWEGELGTD 144
>AB050437-1|BAB40932.1| 457|Homo sapiens beta-site APP cleaving
enzyme I-457 protein.
Length = 457
Score = 40.7 bits (91), Expect = 0.007
Identities = 24/76 (31%), Positives = 37/76 (48%)
Frame = +1
Query: 379 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTSYVANGTQF 558
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 559 AIQYGSGSLSGFLSTD 606
+ Y G G L TD
Sbjct: 129 YVPYTQGKWEGELGTD 144
>AL365205-3|CAM16152.1| 86|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 86
Score = 38.7 bits (86), Expect = 0.029
Identities = 28/70 (40%), Positives = 37/70 (52%), Gaps = 9/70 (12%)
Frame = +1
Query: 226 SVMALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQ 378
+V+ RVPL + K+ R E G E LR KYD + EP++ Y+DA
Sbjct: 18 AVICKQRVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAA 76
Query: 379 YYGVISIGTP 408
Y+G ISIGTP
Sbjct: 77 YFGEISIGTP 86
>BC117433-1|AAI17434.1| 463|Homo sapiens coiled-coil domain
containing 114 protein.
Length = 463
Score = 35.5 bits (78), Expect = 0.27
Identities = 27/96 (28%), Positives = 35/96 (36%), Gaps = 1/96 (1%)
Frame = +1
Query: 631 VRRQTFAEAVSEPGLAFVAAKFDGILGMAF-STIAVDHVTPVFDNMVAQGLVQPVFSFYL 807
V Q AEA + LA AAK DG L + ST T + + + S
Sbjct: 284 VELQEQAEAQRQKDLAAAAAKLDGTLSVDLASTQRAGSSTVLVPTRHPHAIPGSILSHKT 343
Query: 808 NRDPGATTXXXXXXXXSDPAHYRGDLVRGAPTPGHV 915
+RD G+ S H + G P GHV
Sbjct: 344 SRDRGSLGHVTFGGLSSSTGHLPSHITHGDPNTGHV 379
>BC117431-1|AAI17432.1| 463|Homo sapiens coiled-coil domain
containing 114 protein.
Length = 463
Score = 35.5 bits (78), Expect = 0.27
Identities = 27/96 (28%), Positives = 35/96 (36%), Gaps = 1/96 (1%)
Frame = +1
Query: 631 VRRQTFAEAVSEPGLAFVAAKFDGILGMAF-STIAVDHVTPVFDNMVAQGLVQPVFSFYL 807
V Q AEA + LA AAK DG L + ST T + + + S
Sbjct: 284 VELQEQAEAQRQKDLAAAAAKLDGTLSVDLASTQRAGSSTVLVPTRHPHAIPGSILSHKT 343
Query: 808 NRDPGATTXXXXXXXXSDPAHYRGDLVRGAPTPGHV 915
+RD G+ S H + G P GHV
Sbjct: 344 SRDRGSLGHVTFGGLSSSTGHLPSHITHGDPNTGHV 379
>AK057488-1|BAB71508.1| 463|Homo sapiens protein ( Homo sapiens
cDNA FLJ32926 fis, clone TESTI2007358. ).
Length = 463
Score = 35.5 bits (78), Expect = 0.27
Identities = 27/96 (28%), Positives = 35/96 (36%), Gaps = 1/96 (1%)
Frame = +1
Query: 631 VRRQTFAEAVSEPGLAFVAAKFDGILGMAF-STIAVDHVTPVFDNMVAQGLVQPVFSFYL 807
V Q AEA + LA AAK DG L + ST T + + + S
Sbjct: 284 VELQEQAEAQRQKDLAAAAAKLDGTLSVDLASTQRAGSSTVLVPTRHPHAIPGSILSHKT 343
Query: 808 NRDPGATTXXXXXXXXSDPAHYRGDLVRGAPTPGHV 915
+RD G+ S H + G P GHV
Sbjct: 344 SRDRGSLGHVTFGGLSSSTGHLPSHITHGDPNTGHV 379
>AB089958-1|BAC81826.1| 127|Homo sapiens beta-site APP cleaving
enzyme isoform I-127 protein.
Length = 127
Score = 35.5 bits (78), Expect = 0.27
Identities = 18/53 (33%), Positives = 30/53 (56%)
Frame = +1
Query: 379 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTSY 537
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTY 121
>M11437-2|AAB59550.1| 644|Homo sapiens kininogen protein.
Length = 644
Score = 33.1 bits (72), Expect = 1.5
Identities = 22/65 (33%), Positives = 27/65 (41%)
Frame = -2
Query: 798 REDGLHESLSHHVVEHRGHMVHCDSAEGHPEDPVELGGHEGKPGLRHGLGERLAPHLEPA 619
R D HE H + H GH D GH GHE + GL HG +L LE
Sbjct: 428 RHDWGHEKQRKHNLGH-GHKHERDQGHGHQRGHGLGHGHEQQHGLGHGHKFKLDDDLEHQ 486
Query: 618 HGDII 604
G ++
Sbjct: 487 GGHVL 491
>AK126042-1|BAC86409.1| 265|Homo sapiens protein ( Homo sapiens
cDNA FLJ44054 fis, clone TESTI4034212. ).
Length = 265
Score = 31.9 bits (69), Expect = 3.4
Identities = 21/60 (35%), Positives = 29/60 (48%)
Frame = -2
Query: 825 RPGVPVEIEREDGLHESLSHHVVEHRGHMVHCDSAEGHPEDPVELGGHEGKPGLRHGLGE 646
RPGV +R + E L HH + GH+VH + E P L H+ PG+ LG+
Sbjct: 35 RPGV--SHQRAERAFELLLHHDQDALGHLVHVCVHQSCSESPQGL-FHDAHPGVTLTLGQ 91
>BC104851-1|AAI04852.1| 147|Homo sapiens LOC283174 protein protein.
Length = 147
Score = 31.1 bits (67), Expect = 5.9
Identities = 20/75 (26%), Positives = 32/75 (42%)
Frame = +1
Query: 436 TGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTSYVANGTQFAIQYGSGSLSGFLSTDDVT 615
T + LW + + C L N S+ TS++ G+ Q S S FL+ ++
Sbjct: 7 THNGRLWGAGVHLYLSRKQCALKNTSLSKFQTSHICKGSALQPQQASPGASSFLTCPELG 66
Query: 616 VGGLKVRRQTFAEAV 660
V LK+ +AV
Sbjct: 67 VMYLKLVLGQMVQAV 81
>BC101691-1|AAI01692.1| 147|Homo sapiens LOC283174 protein protein.
Length = 147
Score = 31.1 bits (67), Expect = 5.9
Identities = 20/75 (26%), Positives = 32/75 (42%)
Frame = +1
Query: 436 TGSSNLWVPSKKCHYTNITCLLHNKYDSRKSTSYVANGTQFAIQYGSGSLSGFLSTDDVT 615
T + LW + + C L N S+ TS++ G+ Q S S FL+ ++
Sbjct: 7 THNGRLWGAGVHLYLSRKQCALKNTSLSKFQTSHICKGSALQPQQASPGASSFLTCPELG 66
Query: 616 VGGLKVRRQTFAEAV 660
V LK+ +AV
Sbjct: 67 VMYLKLVLGQMVQAV 81
>BC030606-1|AAH30606.2| 514|Homo sapiens coiled-coil domain
containing 11 protein.
Length = 514
Score = 30.7 bits (66), Expect = 7.8
Identities = 12/26 (46%), Positives = 18/26 (69%)
Frame = -2
Query: 444 GSGVEYHLERLRRRADTDHSVVLSIK 367
G G E+HLER+RR ++++ SIK
Sbjct: 30 GQGAEHHLERIRRSHQKHNAILASIK 55
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 129,607,852
Number of Sequences: 237096
Number of extensions: 2806862
Number of successful extensions: 7205
Number of sequences better than 10.0: 79
Number of HSP's better than 10.0 without gapping: 6544
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7083
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11992411152
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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