Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P09_F_F16
(845 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U50159-1|AAA97892.1| 673|Homo sapiens cAMP-specific phoshodiest... 197 5e-50
U50157-1|AAA97890.1| 585|Homo sapiens cAMP-specific phosphodies... 197 5e-50
U02882-1|AAC13745.1| 604|Homo sapiens 3',5'-cyclic AMP phosphod... 197 5e-50
L20970-1|AAA03592.1| 673|Homo sapiens phosphodiesterase protein. 197 5e-50
L20969-1|AAC00042.1| 809|Homo sapiens cyclic AMP phosphodiester... 197 5e-50
AY388960-1|AAQ90404.1| 679|Homo sapiens cAMP-specific phosphodi... 197 5e-50
AY245867-1|AAP75761.1| 679|Homo sapiens cAMP-specific phosphodi... 197 5e-50
AY245866-1|AAP75760.1| 748|Homo sapiens cAMP-specific phosphodi... 197 5e-50
AF536977-1|AAN10119.1| 687|Homo sapiens cAMP-specific phosphodi... 197 5e-50
AF536976-1|AAN10118.1| 748|Homo sapiens cAMP-specific phosphodi... 197 5e-50
AF012073-1|AAC00069.1| 745|Homo sapiens cAMP-specific phosphodi... 197 5e-50
BC036319-1|AAH36319.1| 518|Homo sapiens PDE4D protein protein. 196 6e-50
AF536975-1|AAN10117.1| 518|Homo sapiens cAMP-specific phosphodi... 196 6e-50
U50158-1|AAA97891.1| 507|Homo sapiens cAMP-specific phosphodies... 195 2e-49
AF012074-1|AAC00070.1| 507|Homo sapiens cAMP-specific phosphodi... 195 2e-49
U18087-1|AAC50458.1| 686|Homo sapiens 3',5'-cyclic AMP phosphod... 193 8e-49
S75213-1|AAB33798.1| 667|Homo sapiens type-IVA cyclic AMP speci... 193 8e-49
M37744-1|AAA69697.1| 775|Homo sapiens protein ( Human cyclic AM... 193 8e-49
L20965-1|AAA03588.1| 886|Homo sapiens phosphodiesterase protein. 193 8e-49
AY618547-1|AAU82096.1| 860|Homo sapiens cyclic AMP phosphodiest... 193 8e-49
AY593872-1|AAT00628.1| 864|Homo sapiens cAMP-specific phosphodi... 193 8e-49
AF073745-1|AAD34217.2| 825|Homo sapiens cyclic AMP-specific pho... 193 8e-49
AF069491-2|AAC35015.1| 860|Homo sapiens putative novel cAMP spe... 193 8e-49
AF069491-1|AAC35012.1| 886|Homo sapiens cAMP specific phosphodi... 193 8e-49
U97584-1|AAC25679.1| 647|Homo sapiens cyclic AMP-specific phosp... 192 2e-48
U68532-1|AAC63832.1| 647|Homo sapiens cyclic AMP specific phosp... 192 2e-48
BC038234-1|AAH38234.1| 647|Homo sapiens phosphodiesterase 4A, c... 192 2e-48
BC019864-1|AAH19864.1| 647|Homo sapiens phosphodiesterase 4A, c... 192 2e-48
AF069491-3|AAC35013.1| 647|Homo sapiens cAMP specific phosphodi... 192 2e-48
U85048-1|AAB96381.1| 721|Homo sapiens cyclic AMP specific phosp... 189 1e-47
M97515-1|AAA36426.1| 564|Homo sapiens phosphodiesterase protein. 189 1e-47
L20971-1|AAA03593.1| 564|Homo sapiens phosphodiesterase protein. 189 1e-47
L20966-1|AAA03589.1| 736|Homo sapiens phosphodiesterase protein. 189 1e-47
L12686-1|AAA35643.1| 606|Homo sapiens 3',5'-cyclic AMP phosphod... 189 1e-47
BC105040-1|AAI05041.1| 736|Homo sapiens phosphodiesterase 4B, c... 189 1e-47
BC101480-1|AAI01481.1| 736|Homo sapiens phosphodiesterase 4B, c... 189 1e-47
AL592285-3|CAH70628.1| 721|Homo sapiens phosphodiesterase 4B, c... 189 1e-47
AL592285-1|CAH70626.1| 736|Homo sapiens phosphodiesterase 4B, c... 189 1e-47
AL359701-3|CAI23101.1| 721|Homo sapiens phosphodiesterase 4B, c... 189 1e-47
AL359701-2|CAI23100.1| 564|Homo sapiens phosphodiesterase 4B, c... 189 1e-47
AL359701-1|CAI23099.1| 736|Homo sapiens phosphodiesterase 4B, c... 189 1e-47
AL357273-3|CAH73004.1| 721|Homo sapiens phosphodiesterase 4B, c... 189 1e-47
AL357273-1|CAH73002.1| 736|Homo sapiens phosphodiesterase 4B, c... 189 1e-47
AL109926-4|CAI21751.1| 721|Homo sapiens phosphodiesterase 4B, c... 189 1e-47
AL109926-3|CAI21750.1| 564|Homo sapiens phosphodiesterase 4B, c... 189 1e-47
AL109926-2|CAI21749.1| 736|Homo sapiens phosphodiesterase 4B, c... 189 1e-47
AB209081-1|BAD92318.1| 726|Homo sapiens phosphodiesterase 4B, c... 189 1e-47
EF595686-1|ABQ85407.1| 503|Homo sapiens cAMP-specific phosphodi... 189 1e-47
Z46632-1|CAA86601.1| 712|Homo sapiens 3',5'-cyclic AMP phosphod... 180 8e-45
AF157816-3|AAD47055.1| 606|Homo sapiens cAMP specific phosphodi... 179 1e-44
AF157816-2|AAD47054.1| 680|Homo sapiens cAMP specific phosphodi... 179 1e-44
AF157816-1|AAD47053.1| 712|Homo sapiens cAMP specific phosphodi... 179 1e-44
AC005759-2|AAC83047.1| 710|Homo sapiens CN4C_HUMAN protein. 179 1e-44
AC005759-1|AAC83050.1| 782|Homo sapiens PDE4C-791 protein. 179 1e-44
U66348-1|AAB96877.1| 518|Homo sapiens PDE4C-delta54 protein. 179 1e-44
AC005759-3|AAC83051.1| 518|Homo sapiens PDE4C-delta54 protein. 179 1e-44
U88713-1|AAC51916.1| 700|Homo sapiens phosphodiesterase 4C prot... 177 3e-44
U88712-1|AAC51915.1| 606|Homo sapiens phosphodiesterase 4C prot... 177 3e-44
U66346-1|AAB96875.1| 791|Homo sapiens PDE4C-791 protein. 177 3e-44
BC109068-1|AAI09069.1| 549|Homo sapiens PDE4C protein protein. 177 3e-44
BC109067-1|AAI09068.1| 481|Homo sapiens PDE4C protein protein. 177 4e-44
AC005759-5|AAC83049.1| 426|Homo sapiens PDE4C-426 protein. 129 1e-29
U66347-1|AAB96876.1| 426|Homo sapiens PDE4C-426 protein. 127 4e-29
U79571-1|AAC51928.1| 205|Homo sapiens 3'5' cyclic nucleotide ph... 126 1e-28
AC005759-4|AAC83048.1| 427|Homo sapiens PDE4C-delta109 protein. 114 3e-25
U66349-1|AAB96878.1| 427|Homo sapiens PDE4C-delta109 protein. 113 1e-24
U18088-1|AAA98540.1| 323|Homo sapiens 3',5'-cyclic AMP phosphod... 102 2e-21
AF069491-4|AAC35014.1| 323|Homo sapiens cAMP specific phosphodi... 102 2e-21
U40370-1|AAC50436.1| 535|Homo sapiens 3',5' cyclic nucleotide p... 63 1e-09
BC022480-1|AAH22480.1| 545|Homo sapiens phosphodiesterase 1A, c... 63 1e-09
AL110263-1|CAB53703.1| 519|Homo sapiens hypothetical protein pr... 63 1e-09
AJ401610-1|CAC82208.1| 519|Homo sapiens 3'5' cyclic nucleotide ... 63 1e-09
AB038224-9|BAB20054.1| 518|Homo sapiens calmodulin-dependent ph... 63 1e-09
AB038224-8|BAB20053.1| 501|Homo sapiens calmodulin-dependent ph... 63 1e-09
AB038224-7|BAB20057.1| 511|Homo sapiens calmodulin-dependent ph... 63 1e-09
AB038224-6|BAB20052.1| 552|Homo sapiens calmodulin-dependent ph... 63 1e-09
AB038224-5|BAB20050.1| 535|Homo sapiens calmodulin-dependent ph... 63 1e-09
AB038224-4|BAB20056.1| 545|Homo sapiens calmodulin-dependent ph... 63 1e-09
AB038224-3|BAB20051.1| 536|Homo sapiens calmodulin-dependent ph... 63 1e-09
AB038224-2|BAB20049.1| 519|Homo sapiens calmodulin-dependent ph... 63 1e-09
AB038224-1|BAB20055.1| 529|Homo sapiens calmodulin-dependent ph... 63 1e-09
U40371-1|AAC50437.1| 634|Homo sapiens 3',5' cyclic nucleotide p... 62 2e-09
BC022525-1|AAH22525.1| 634|Homo sapiens PDE1C protein protein. 62 2e-09
BC022479-1|AAH22479.1| 634|Homo sapiens PDE1C protein protein. 62 2e-09
AC006377-1|AAS07516.1| 591|Homo sapiens unknown protein. 62 2e-09
U40372-1|AAA96961.1| 564|Homo sapiens PDE1C3 protein. 62 3e-09
EF108327-1|ABL14249.1| 502|Homo sapiens phosphodiesterase PDE7B... 62 3e-09
BC075083-1|AAH75083.1| 450|Homo sapiens phosphodiesterase 7B pr... 62 3e-09
BC075082-1|AAH75082.1| 450|Homo sapiens phosphodiesterase 7B pr... 62 3e-09
AL360178-1|CAH73075.1| 450|Homo sapiens phosphodiesterase 7B pr... 62 3e-09
AL138828-4|CAI95287.1| 450|Homo sapiens phosphodiesterase 7B pr... 62 3e-09
AL138828-3|CAI95286.1| 199|Homo sapiens phosphodiesterase 7B pr... 62 3e-09
AL133319-1|CAH73332.1| 450|Homo sapiens phosphodiesterase 7B pr... 62 3e-09
AK091734-1|BAC03734.1| 769|Homo sapiens (EC 3.1.4.17). protein. 62 3e-09
AJ251860-1|CAB92441.1| 450|Homo sapiens phosphodiesterase 7B pr... 62 3e-09
AB209990-1|BAE06072.1| 586|Homo sapiens PDE7B variant protein p... 62 3e-09
AB038040-1|BAA96537.1| 450|Homo sapiens cyclic nucleotide phosp... 62 3e-09
U67932-1|AAB65772.1| 456|Homo sapiens cAMP phosphodiesterase PD... 59 2e-08
L12052-1|AAA35644.2| 482|Homo sapiens cAMP phosphodiesterase PD... 59 2e-08
BC126360-1|AAI26361.1| 456|Homo sapiens phosphodiesterase 7A pr... 59 2e-08
AF332652-1|AAK57640.1| 424|Homo sapiens cAMP-specific cyclic nu... 59 2e-08
U86078-1|AAC51872.1| 536|Homo sapiens calmodulin-stimulated pho... 54 5e-07
U56976-1|AAC50769.1| 536|Homo sapiens calmodulin dependent phos... 54 5e-07
BC032226-1|AAH32226.1| 536|Homo sapiens phosphodiesterase 1B, c... 54 5e-07
AJ401609-1|CAC82207.1| 516|Homo sapiens 3'5' cyclic nucleotide ... 54 5e-07
BX538092-1|CAD98011.1| 399|Homo sapiens hypothetical protein pr... 53 1e-06
U36798-1|AAB18673.1| 1141|Homo sapiens platelet cGI-PDE protein. 50 1e-05
M91667-1|AAA35912.2| 1141|Homo sapiens cGMP-inhibited cAMP phosp... 50 1e-05
BC117371-1|AAI17372.1| 1141|Homo sapiens phosphodiesterase 3A, c... 50 1e-05
BC117369-1|AAI17370.1| 1141|Homo sapiens phosphodiesterase 3A, c... 50 1e-05
AJ005036-1|CAA06304.1| 1141|Homo sapiens phosphodiesterase 3A pr... 50 1e-05
X95520-1|CAA64774.1| 1112|Homo sapiens cyclic nucleotide phospho... 49 2e-05
U38178-1|AAC50724.1| 1112|Homo sapiens cyclic nucleotide phophod... 49 2e-05
D50640-1|BAA09306.1| 1112|Homo sapiens phosphodiesterase 3B prot... 49 2e-05
BC150307-1|AAI50308.1| 1112|Homo sapiens phosphodiesterase 3B, c... 49 2e-05
AY459346-1|AAR24292.1| 1112|Homo sapiens cGMP-inhibited cAMP pho... 49 2e-05
BC075822-1|AAH75822.1| 829|Homo sapiens phosphodiesterase 8A pr... 46 2e-04
BC060762-1|AAH60762.1| 829|Homo sapiens phosphodiesterase 8A pr... 46 2e-04
AF388187-1|AAL18614.1| 582|Homo sapiens cAMP phosphodiesterase ... 46 2e-04
AF388186-1|AAL18613.1| 582|Homo sapiens cAMP phosphodiesterase ... 46 2e-04
AF388185-1|AAL18612.1| 449|Homo sapiens cAMP phosphodiesterase ... 46 2e-04
AF388184-1|AAL18611.1| 783|Homo sapiens cAMP phosphodiesterase ... 46 2e-04
AF388183-1|AAL18610.1| 829|Homo sapiens cAMP phosphodiesterase ... 46 2e-04
AF332653-1|AAK57641.1| 829|Homo sapiens cAMP-specific cyclic nu... 46 2e-04
AF056490-1|AAC39763.1| 713|Homo sapiens cAMP-specific phosphodi... 46 2e-04
BC035144-1|AAH35144.1| 385|Homo sapiens PDE8B protein protein. 42 0.004
AY423729-1|AAS00492.1| 350|Homo sapiens proliferation-inducing ... 42 0.004
AY129950-3|AAN71727.1| 788|Homo sapiens cAMP-specific phosphodi... 42 0.004
AY129950-2|AAN71726.1| 838|Homo sapiens cAMP-specific phosphodi... 42 0.004
AY129950-1|AAN71725.1| 885|Homo sapiens cAMP-specific phosphodi... 42 0.004
AY129949-1|AAN71724.1| 788|Homo sapiens cAMP-specific phosphodi... 42 0.004
AY129948-1|AAN71723.1| 838|Homo sapiens cAMP-specific phosphodi... 42 0.004
AL831924-1|CAD38584.1| 843|Homo sapiens hypothetical protein pr... 42 0.004
AF079529-1|AAC69564.2| 885|Homo sapiens cAMP-specific phosphodi... 42 0.004
AB085827-1|BAC53765.1| 865|Homo sapiens phosphodiesterase 8B4 p... 42 0.004
AB085826-1|BAC53764.1| 830|Homo sapiens phosphodiesterase 8B3 p... 42 0.004
AB085825-1|BAC53763.1| 788|Homo sapiens phosphodiestearse 8B2 p... 42 0.004
AB085824-1|BAC53762.1| 885|Homo sapiens phosphodiesterase 8B1 p... 42 0.004
BC048317-1|AAH48317.1| 305|Homo sapiens PDE8A protein protein. 34 0.75
U40584-1|AAB50018.1| 184|Homo sapiens calcium/calmodulin-stimul... 33 0.99
>U50159-1|AAA97892.1| 673|Homo sapiens cAMP-specific
phoshodiesterase HPDE4D3 variant protein.
Length = 673
Score = 197 bits (480), Expect = 5e-50
Identities = 98/203 (48%), Positives = 139/203 (68%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKRMLN+EL+H SE S+SGNQ+SE+I +TFLDKQ E+++PS +++ +K
Sbjct: 166 EMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPS-----PTQKEKEK 220
Query: 414 KEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVD 593
K++P MSQISGVK+ L H++S T +PR+GV+T D+++WG+
Sbjct: 221 KKRP--------MSQISGVKK-LMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLH 271
Query: 594 IFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHA 773
+FRI +LS RPLT + +T F R+LL T +IP T + + +TL +HY D +HN++HA
Sbjct: 272 VFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHA 331
Query: 774 ADVTQSTNVLLNTPALNAVFTPL 842
ADV QST+VLL+TPAL AVFT L
Sbjct: 332 ADVVQSTHVLLSTPALEAVFTDL 354
>U50157-1|AAA97890.1| 585|Homo sapiens cAMP-specific
phosphodiesterase HPDE4D1 variant protein.
Length = 585
Score = 197 bits (480), Expect = 5e-50
Identities = 98/203 (48%), Positives = 139/203 (68%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKRMLN+EL+H SE S+SGNQ+SE+I +TFLDKQ E+++PS +++ +K
Sbjct: 78 EMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPS-----PTQKEKEK 132
Query: 414 KEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVD 593
K++P MSQISGVK+ L H++S T +PR+GV+T D+++WG+
Sbjct: 133 KKRP--------MSQISGVKK-LMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLH 183
Query: 594 IFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHA 773
+FRI +LS RPLT + +T F R+LL T +IP T + + +TL +HY D +HN++HA
Sbjct: 184 VFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHA 243
Query: 774 ADVTQSTNVLLNTPALNAVFTPL 842
ADV QST+VLL+TPAL AVFT L
Sbjct: 244 ADVVQSTHVLLSTPALEAVFTDL 266
>U02882-1|AAC13745.1| 604|Homo sapiens 3',5'-cyclic AMP
phosphodiesterase protein.
Length = 604
Score = 197 bits (480), Expect = 5e-50
Identities = 98/203 (48%), Positives = 139/203 (68%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKRMLN+EL+H SE S+SGNQ+SE+I +TFLDKQ E+++PS +++ +K
Sbjct: 97 EMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPS-----PTQKEKEK 151
Query: 414 KEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVD 593
K++P MSQISGVK+ L H++S T +PR+GV+T D+++WG+
Sbjct: 152 KKRP--------MSQISGVKK-LMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLH 202
Query: 594 IFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHA 773
+FRI +LS RPLT + +T F R+LL T +IP T + + +TL +HY D +HN++HA
Sbjct: 203 VFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHA 262
Query: 774 ADVTQSTNVLLNTPALNAVFTPL 842
ADV QST+VLL+TPAL AVFT L
Sbjct: 263 ADVVQSTHVLLSTPALEAVFTDL 285
>L20970-1|AAA03592.1| 673|Homo sapiens phosphodiesterase protein.
Length = 673
Score = 197 bits (480), Expect = 5e-50
Identities = 98/203 (48%), Positives = 139/203 (68%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKRMLN+EL+H SE S+SGNQ+SE+I +TFLDKQ E+++PS +++ +K
Sbjct: 166 EMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPS-----PTQKEKEK 220
Query: 414 KEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVD 593
K++P MSQISGVK+ L H++S T +PR+GV+T D+++WG+
Sbjct: 221 KKRP--------MSQISGVKK-LMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLH 271
Query: 594 IFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHA 773
+FRI +LS RPLT + +T F R+LL T +IP T + + +TL +HY D +HN++HA
Sbjct: 272 VFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHA 331
Query: 774 ADVTQSTNVLLNTPALNAVFTPL 842
ADV QST+VLL+TPAL AVFT L
Sbjct: 332 ADVVQSTHVLLSTPALEAVFTDL 354
>L20969-1|AAC00042.1| 809|Homo sapiens cyclic AMP phosphodiesterase
protein.
Length = 809
Score = 197 bits (480), Expect = 5e-50
Identities = 98/203 (48%), Positives = 139/203 (68%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKRMLN+EL+H SE S+SGNQ+SE+I +TFLDKQ E+++PS +++ +K
Sbjct: 302 EMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPS-----PTQKEKEK 356
Query: 414 KEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVD 593
K++P MSQISGVK+ L H++S T +PR+GV+T D+++WG+
Sbjct: 357 KKRP--------MSQISGVKK-LMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLH 407
Query: 594 IFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHA 773
+FRI +LS RPLT + +T F R+LL T +IP T + + +TL +HY D +HN++HA
Sbjct: 408 VFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHA 467
Query: 774 ADVTQSTNVLLNTPALNAVFTPL 842
ADV QST+VLL+TPAL AVFT L
Sbjct: 468 ADVVQSTHVLLSTPALEAVFTDL 490
>AY388960-1|AAQ90404.1| 679|Homo sapiens cAMP-specific
phosphodiesterase PDE4D9 protein.
Length = 679
Score = 197 bits (480), Expect = 5e-50
Identities = 98/203 (48%), Positives = 139/203 (68%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKRMLN+EL+H SE S+SGNQ+SE+I +TFLDKQ E+++PS +++ +K
Sbjct: 172 EMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPS-----PTQKEKEK 226
Query: 414 KEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVD 593
K++P MSQISGVK+ L H++S T +PR+GV+T D+++WG+
Sbjct: 227 KKRP--------MSQISGVKK-LMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLH 277
Query: 594 IFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHA 773
+FRI +LS RPLT + +T F R+LL T +IP T + + +TL +HY D +HN++HA
Sbjct: 278 VFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHA 337
Query: 774 ADVTQSTNVLLNTPALNAVFTPL 842
ADV QST+VLL+TPAL AVFT L
Sbjct: 338 ADVVQSTHVLLSTPALEAVFTDL 360
>AY245867-1|AAP75761.1| 679|Homo sapiens cAMP-specific
phosphodiesterase variant PDE4D9 protein.
Length = 679
Score = 197 bits (480), Expect = 5e-50
Identities = 98/203 (48%), Positives = 139/203 (68%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKRMLN+EL+H SE S+SGNQ+SE+I +TFLDKQ E+++PS +++ +K
Sbjct: 172 EMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPS-----PTQKEKEK 226
Query: 414 KEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVD 593
K++P MSQISGVK+ L H++S T +PR+GV+T D+++WG+
Sbjct: 227 KKRP--------MSQISGVKK-LMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLH 277
Query: 594 IFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHA 773
+FRI +LS RPLT + +T F R+LL T +IP T + + +TL +HY D +HN++HA
Sbjct: 278 VFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHA 337
Query: 774 ADVTQSTNVLLNTPALNAVFTPL 842
ADV QST+VLL+TPAL AVFT L
Sbjct: 338 ADVVQSTHVLLSTPALEAVFTDL 360
>AY245866-1|AAP75760.1| 748|Homo sapiens cAMP-specific
phosphodiesterase variant PDE4D7 protein.
Length = 748
Score = 197 bits (480), Expect = 5e-50
Identities = 98/203 (48%), Positives = 139/203 (68%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKRMLN+EL+H SE S+SGNQ+SE+I +TFLDKQ E+++PS +++ +K
Sbjct: 241 EMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPS-----PTQKEKEK 295
Query: 414 KEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVD 593
K++P MSQISGVK+ L H++S T +PR+GV+T D+++WG+
Sbjct: 296 KKRP--------MSQISGVKK-LMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLH 346
Query: 594 IFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHA 773
+FRI +LS RPLT + +T F R+LL T +IP T + + +TL +HY D +HN++HA
Sbjct: 347 VFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHA 406
Query: 774 ADVTQSTNVLLNTPALNAVFTPL 842
ADV QST+VLL+TPAL AVFT L
Sbjct: 407 ADVVQSTHVLLSTPALEAVFTDL 429
>AF536977-1|AAN10119.1| 687|Homo sapiens cAMP-specific
phosphodiesterase PDE4D8 protein.
Length = 687
Score = 197 bits (480), Expect = 5e-50
Identities = 98/203 (48%), Positives = 139/203 (68%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKRMLN+EL+H SE S+SGNQ+SE+I +TFLDKQ E+++PS +++ +K
Sbjct: 180 EMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPS-----PTQKEKEK 234
Query: 414 KEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVD 593
K++P MSQISGVK+ L H++S T +PR+GV+T D+++WG+
Sbjct: 235 KKRP--------MSQISGVKK-LMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLH 285
Query: 594 IFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHA 773
+FRI +LS RPLT + +T F R+LL T +IP T + + +TL +HY D +HN++HA
Sbjct: 286 VFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHA 345
Query: 774 ADVTQSTNVLLNTPALNAVFTPL 842
ADV QST+VLL+TPAL AVFT L
Sbjct: 346 ADVVQSTHVLLSTPALEAVFTDL 368
>AF536976-1|AAN10118.1| 748|Homo sapiens cAMP-specific
phosphodiesterase PDE4D7 protein.
Length = 748
Score = 197 bits (480), Expect = 5e-50
Identities = 98/203 (48%), Positives = 139/203 (68%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKRMLN+EL+H SE S+SGNQ+SE+I +TFLDKQ E+++PS +++ +K
Sbjct: 241 EMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPS-----PTQKEKEK 295
Query: 414 KEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVD 593
K++P MSQISGVK+ L H++S T +PR+GV+T D+++WG+
Sbjct: 296 KKRP--------MSQISGVKK-LMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLH 346
Query: 594 IFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHA 773
+FRI +LS RPLT + +T F R+LL T +IP T + + +TL +HY D +HN++HA
Sbjct: 347 VFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHA 406
Query: 774 ADVTQSTNVLLNTPALNAVFTPL 842
ADV QST+VLL+TPAL AVFT L
Sbjct: 407 ADVVQSTHVLLSTPALEAVFTDL 429
>AF012073-1|AAC00069.1| 745|Homo sapiens cAMP-specific
phosphodiesterase PDE4D5 protein.
Length = 745
Score = 197 bits (480), Expect = 5e-50
Identities = 98/203 (48%), Positives = 139/203 (68%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKRMLN+EL+H SE S+SGNQ+SE+I +TFLDKQ E+++PS +++ +K
Sbjct: 238 EMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPS-----PTQKEKEK 292
Query: 414 KEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVD 593
K++P MSQISGVK+ L H++S T +PR+GV+T D+++WG+
Sbjct: 293 KKRP--------MSQISGVKK-LMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLH 343
Query: 594 IFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHA 773
+FRI +LS RPLT + +T F R+LL T +IP T + + +TL +HY D +HN++HA
Sbjct: 344 VFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHA 403
Query: 774 ADVTQSTNVLLNTPALNAVFTPL 842
ADV QST+VLL+TPAL AVFT L
Sbjct: 404 ADVVQSTHVLLSTPALEAVFTDL 426
>BC036319-1|AAH36319.1| 518|Homo sapiens PDE4D protein protein.
Length = 518
Score = 196 bits (479), Expect = 6e-50
Identities = 97/205 (47%), Positives = 140/205 (68%)
Frame = +3
Query: 228 SIEMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGA 407
S+ + +FKRMLN+EL+H SE S+SGNQ+SE+I +TFLDKQ E+++PS +++
Sbjct: 9 SVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPS-----PTQKEK 63
Query: 408 KKKEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWG 587
+KK++P MSQISGVK+ L H++S T +PR+GV+T D+++WG
Sbjct: 64 EKKKRP--------MSQISGVKK-LMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWG 114
Query: 588 VDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSL 767
+ +FRI +LS RPLT + +T F R+LL T +IP T + + +TL +HY D +HN++
Sbjct: 115 LHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNI 174
Query: 768 HAADVTQSTNVLLNTPALNAVFTPL 842
HAADV QST+VLL+TPAL AVFT L
Sbjct: 175 HAADVVQSTHVLLSTPALEAVFTDL 199
>AF536975-1|AAN10117.1| 518|Homo sapiens cAMP-specific
phosphodiesterase PDE4D6 protein.
Length = 518
Score = 196 bits (479), Expect = 6e-50
Identities = 97/205 (47%), Positives = 140/205 (68%)
Frame = +3
Query: 228 SIEMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGA 407
S+ + +FKRMLN+EL+H SE S+SGNQ+SE+I +TFLDKQ E+++PS +++
Sbjct: 9 SVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPS-----PTQKEK 63
Query: 408 KKKEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWG 587
+KK++P MSQISGVK+ L H++S T +PR+GV+T D+++WG
Sbjct: 64 EKKKRP--------MSQISGVKK-LMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWG 114
Query: 588 VDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSL 767
+ +FRI +LS RPLT + +T F R+LL T +IP T + + +TL +HY D +HN++
Sbjct: 115 LHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNI 174
Query: 768 HAADVTQSTNVLLNTPALNAVFTPL 842
HAADV QST+VLL+TPAL AVFT L
Sbjct: 175 HAADVVQSTHVLLSTPALEAVFTDL 199
>U50158-1|AAA97891.1| 507|Homo sapiens cAMP-specific
phosphodiesterase HPDE4D2 variant protein.
Length = 507
Score = 195 bits (475), Expect = 2e-49
Identities = 96/198 (48%), Positives = 137/198 (69%)
Frame = +3
Query: 249 QFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKKKEKPR 428
+FKRMLN+EL+H SE S+SGNQ+SE+I +TFLDKQ E+++PS +++ +KK++P
Sbjct: 5 KFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPS-----PTQKEKEKKKRP- 58
Query: 429 HGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVDIFRIG 608
MSQISGVK+ L H++S T +PR+GV+T D+++WG+ +FRI
Sbjct: 59 -------MSQISGVKK-LMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIA 110
Query: 609 DLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHAADVTQ 788
+LS RPLT + +T F R+LL T +IP T + + +TL +HY D +HN++HAADV Q
Sbjct: 111 ELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQ 170
Query: 789 STNVLLNTPALNAVFTPL 842
ST+VLL+TPAL AVFT L
Sbjct: 171 STHVLLSTPALEAVFTDL 188
>AF012074-1|AAC00070.1| 507|Homo sapiens cAMP-specific
phosphodiesterase PDE4D2 protein.
Length = 507
Score = 195 bits (475), Expect = 2e-49
Identities = 96/198 (48%), Positives = 137/198 (69%)
Frame = +3
Query: 249 QFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKKKEKPR 428
+FKRMLN+EL+H SE S+SGNQ+SE+I +TFLDKQ E+++PS +++ +KK++P
Sbjct: 5 KFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPS-----PTQKEKEKKKRP- 58
Query: 429 HGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVDIFRIG 608
MSQISGVK+ L H++S T +PR+GV+T D+++WG+ +FRI
Sbjct: 59 -------MSQISGVKK-LMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIA 110
Query: 609 DLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHAADVTQ 788
+LS RPLT + +T F R+LL T +IP T + + +TL +HY D +HN++HAADV Q
Sbjct: 111 ELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQ 170
Query: 789 STNVLLNTPALNAVFTPL 842
ST+VLL+TPAL AVFT L
Sbjct: 171 STHVLLSTPALEAVFTDL 188
>U18087-1|AAC50458.1| 686|Homo sapiens 3',5'-cyclic AMP
phosphodiesterase HPDE4A6 protein.
Length = 686
Score = 193 bits (470), Expect = 8e-49
Identities = 96/207 (46%), Positives = 135/207 (65%), Gaps = 4/207 (1%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKRMLN+EL+H SE S+SGNQ+SEYI +TFLDKQ E+++PS ++E ++ A +
Sbjct: 56 EMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPR 115
Query: 414 KEKPRHGGPATT----MSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDR 581
+ P MSQI+G+K+ L H+NS +PR+GV+T +L++
Sbjct: 116 PRPSQPPPPPVPHLQPMSQITGLKK-LMHSNSLNNSNIPRFGVKTDQEELLAQELENLNK 174
Query: 582 WGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHN 761
WG++IF + D + GR LT + Y F R+LL +IP T + + +TL +HY D +HN
Sbjct: 175 WGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHN 234
Query: 762 SLHAADVTQSTNVLLNTPALNAVFTPL 842
SLHAADV QST+VLL TPAL+AVFT L
Sbjct: 235 SLHAADVLQSTHVLLATPALDAVFTDL 261
>S75213-1|AAB33798.1| 667|Homo sapiens type-IVA cyclic AMP specific
phosphodiesterase protein.
Length = 667
Score = 193 bits (470), Expect = 8e-49
Identities = 96/207 (46%), Positives = 135/207 (65%), Gaps = 4/207 (1%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKRMLN+EL+H SE S+SGNQ+SEYI +TFLDKQ E+++PS ++E ++ A +
Sbjct: 37 EMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPR 96
Query: 414 KEKPRHGGPATT----MSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDR 581
+ P MSQI+G+K+ L H+NS +PR+GV+T +L++
Sbjct: 97 PRPSQPPPPPVPHLQPMSQITGLKK-LMHSNSLNNSNIPRFGVKTDQEELLAQELENLNK 155
Query: 582 WGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHN 761
WG++IF + D + GR LT + Y F R+LL +IP T + + +TL +HY D +HN
Sbjct: 156 WGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHN 215
Query: 762 SLHAADVTQSTNVLLNTPALNAVFTPL 842
SLHAADV QST+VLL TPAL+AVFT L
Sbjct: 216 SLHAADVLQSTHVLLATPALDAVFTDL 242
>M37744-1|AAA69697.1| 775|Homo sapiens protein ( Human cyclic AMP
(cAMP)-specific phosphodiesterase mRNA, complete cds. ).
Length = 775
Score = 193 bits (470), Expect = 8e-49
Identities = 96/207 (46%), Positives = 135/207 (65%), Gaps = 4/207 (1%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKRMLN+EL+H SE S+SGNQ+SEYI +TFLDKQ E+++PS ++E ++ A +
Sbjct: 145 EMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPR 204
Query: 414 KEKPRHGGPATT----MSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDR 581
+ P MSQI+G+K+ L H+NS +PR+GV+T +L++
Sbjct: 205 PRPSQPPPPPVPHLQPMSQITGLKK-LMHSNSLNNSNIPRFGVKTDQEELLAQELENLNK 263
Query: 582 WGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHN 761
WG++IF + D + GR LT + Y F R+LL +IP T + + +TL +HY D +HN
Sbjct: 264 WGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHN 323
Query: 762 SLHAADVTQSTNVLLNTPALNAVFTPL 842
SLHAADV QST+VLL TPAL+AVFT L
Sbjct: 324 SLHAADVLQSTHVLLATPALDAVFTDL 350
>L20965-1|AAA03588.1| 886|Homo sapiens phosphodiesterase protein.
Length = 886
Score = 193 bits (470), Expect = 8e-49
Identities = 96/207 (46%), Positives = 135/207 (65%), Gaps = 4/207 (1%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKRMLN+EL+H SE S+SGNQ+SEYI +TFLDKQ E+++PS ++E ++ A +
Sbjct: 256 EMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPR 315
Query: 414 KEKPRHGGPATT----MSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDR 581
+ P MSQI+G+K+ L H+NS +PR+GV+T +L++
Sbjct: 316 PRPSQPPPPPVPHLQPMSQITGLKK-LMHSNSLNNSNIPRFGVKTDQEELLAQELENLNK 374
Query: 582 WGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHN 761
WG++IF + D + GR LT + Y F R+LL +IP T + + +TL +HY D +HN
Sbjct: 375 WGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHN 434
Query: 762 SLHAADVTQSTNVLLNTPALNAVFTPL 842
SLHAADV QST+VLL TPAL+AVFT L
Sbjct: 435 SLHAADVLQSTHVLLATPALDAVFTDL 461
>AY618547-1|AAU82096.1| 860|Homo sapiens cyclic AMP
phosphodiesterase PDE4A11 protein.
Length = 860
Score = 193 bits (470), Expect = 8e-49
Identities = 96/207 (46%), Positives = 135/207 (65%), Gaps = 4/207 (1%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKRMLN+EL+H SE S+SGNQ+SEYI +TFLDKQ E+++PS ++E ++ A +
Sbjct: 230 EMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPR 289
Query: 414 KEKPRHGGPATT----MSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDR 581
+ P MSQI+G+K+ L H+NS +PR+GV+T +L++
Sbjct: 290 PRPSQPPPPPVPHLQPMSQITGLKK-LMHSNSLNNSNIPRFGVKTDQEELLAQELENLNK 348
Query: 582 WGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHN 761
WG++IF + D + GR LT + Y F R+LL +IP T + + +TL +HY D +HN
Sbjct: 349 WGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHN 408
Query: 762 SLHAADVTQSTNVLLNTPALNAVFTPL 842
SLHAADV QST+VLL TPAL+AVFT L
Sbjct: 409 SLHAADVLQSTHVLLATPALDAVFTDL 435
>AY593872-1|AAT00628.1| 864|Homo sapiens cAMP-specific
phosphodiesterase protein.
Length = 864
Score = 193 bits (470), Expect = 8e-49
Identities = 96/207 (46%), Positives = 135/207 (65%), Gaps = 4/207 (1%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKRMLN+EL+H SE S+SGNQ+SEYI +TFLDKQ E+++PS ++E ++ A +
Sbjct: 234 EMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPR 293
Query: 414 KEKPRHGGPATT----MSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDR 581
+ P MSQI+G+K+ L H+NS +PR+GV+T +L++
Sbjct: 294 PRPSQPPPPPVPHLQPMSQITGLKK-LMHSNSLNNSNIPRFGVKTDQEELLAQELENLNK 352
Query: 582 WGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHN 761
WG++IF + D + GR LT + Y F R+LL +IP T + + +TL +HY D +HN
Sbjct: 353 WGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHN 412
Query: 762 SLHAADVTQSTNVLLNTPALNAVFTPL 842
SLHAADV QST+VLL TPAL+AVFT L
Sbjct: 413 SLHAADVLQSTHVLLATPALDAVFTDL 439
>AF073745-1|AAD34217.2| 825|Homo sapiens cyclic AMP-specific
phosphodiesterase HSPDE4A10 protein.
Length = 825
Score = 193 bits (470), Expect = 8e-49
Identities = 96/207 (46%), Positives = 135/207 (65%), Gaps = 4/207 (1%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKRMLN+EL+H SE S+SGNQ+SEYI +TFLDKQ E+++PS ++E ++ A +
Sbjct: 195 EMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPR 254
Query: 414 KEKPRHGGPATT----MSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDR 581
+ P MSQI+G+K+ L H+NS +PR+GV+T +L++
Sbjct: 255 PRPSQPPPPPVPHLQPMSQITGLKK-LMHSNSLNNSNIPRFGVKTDQEELLAQELENLNK 313
Query: 582 WGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHN 761
WG++IF + D + GR LT + Y F R+LL +IP T + + +TL +HY D +HN
Sbjct: 314 WGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHN 373
Query: 762 SLHAADVTQSTNVLLNTPALNAVFTPL 842
SLHAADV QST+VLL TPAL+AVFT L
Sbjct: 374 SLHAADVLQSTHVLLATPALDAVFTDL 400
>AF069491-2|AAC35015.1| 860|Homo sapiens putative novel cAMP
specific phosphodiesterase 4A variant protein.
Length = 860
Score = 193 bits (470), Expect = 8e-49
Identities = 96/207 (46%), Positives = 135/207 (65%), Gaps = 4/207 (1%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKRMLN+EL+H SE S+SGNQ+SEYI +TFLDKQ E+++PS ++E ++ A +
Sbjct: 230 EMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPR 289
Query: 414 KEKPRHGGPATT----MSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDR 581
+ P MSQI+G+K+ L H+NS +PR+GV+T +L++
Sbjct: 290 PRPSQPPPPPVPHLQPMSQITGLKK-LMHSNSLNNSNIPRFGVKTDQEELLAQELENLNK 348
Query: 582 WGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHN 761
WG++IF + D + GR LT + Y F R+LL +IP T + + +TL +HY D +HN
Sbjct: 349 WGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHN 408
Query: 762 SLHAADVTQSTNVLLNTPALNAVFTPL 842
SLHAADV QST+VLL TPAL+AVFT L
Sbjct: 409 SLHAADVLQSTHVLLATPALDAVFTDL 435
>AF069491-1|AAC35012.1| 886|Homo sapiens cAMP specific
phosphodiesterase 4A variant pde46 protein.
Length = 886
Score = 193 bits (470), Expect = 8e-49
Identities = 96/207 (46%), Positives = 135/207 (65%), Gaps = 4/207 (1%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKRMLN+EL+H SE S+SGNQ+SEYI +TFLDKQ E+++PS ++E ++ A +
Sbjct: 256 EMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPR 315
Query: 414 KEKPRHGGPATT----MSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDR 581
+ P MSQI+G+K+ L H+NS +PR+GV+T +L++
Sbjct: 316 PRPSQPPPPPVPHLQPMSQITGLKK-LMHSNSLNNSNIPRFGVKTDQEELLAQELENLNK 374
Query: 582 WGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHN 761
WG++IF + D + GR LT + Y F R+LL +IP T + + +TL +HY D +HN
Sbjct: 375 WGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHN 434
Query: 762 SLHAADVTQSTNVLLNTPALNAVFTPL 842
SLHAADV QST+VLL TPAL+AVFT L
Sbjct: 435 SLHAADVLQSTHVLLATPALDAVFTDL 461
>U97584-1|AAC25679.1| 647|Homo sapiens cyclic AMP-specific
phosphodiesterase HSPDE4A1A protein.
Length = 647
Score = 192 bits (467), Expect = 2e-48
Identities = 95/202 (47%), Positives = 133/202 (65%), Gaps = 4/202 (1%)
Frame = +3
Query: 249 QFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKKKEKPR 428
QFKRMLN+EL+H SE S+SGNQ+SEYI +TFLDKQ E+++PS ++E ++ A + +
Sbjct: 22 QFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQ 81
Query: 429 HGGPATT----MSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVDI 596
P MSQI+G+K+ L H+NS +PR+GV+T +L++WG++I
Sbjct: 82 PPPPPVPHLQPMSQITGLKK-LMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNI 140
Query: 597 FRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHAA 776
F + D + GR LT + Y F R+LL +IP T + + +TL +HY D +HNSLHAA
Sbjct: 141 FCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHNSLHAA 200
Query: 777 DVTQSTNVLLNTPALNAVFTPL 842
DV QST+VLL TPAL+AVFT L
Sbjct: 201 DVLQSTHVLLATPALDAVFTDL 222
>U68532-1|AAC63832.1| 647|Homo sapiens cyclic AMP specific
phosphodiesterase RD1 protein.
Length = 647
Score = 192 bits (467), Expect = 2e-48
Identities = 95/202 (47%), Positives = 133/202 (65%), Gaps = 4/202 (1%)
Frame = +3
Query: 249 QFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKKKEKPR 428
QFKRMLN+EL+H SE S+SGNQ+SEYI +TFLDKQ E+++PS ++E ++ A + +
Sbjct: 22 QFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQ 81
Query: 429 HGGPATT----MSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVDI 596
P MSQI+G+K+ L H+NS +PR+GV+T +L++WG++I
Sbjct: 82 PPPPPVPHLQPMSQITGLKK-LMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNI 140
Query: 597 FRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHAA 776
F + D + GR LT + Y F R+LL +IP T + + +TL +HY D +HNSLHAA
Sbjct: 141 FCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHNSLHAA 200
Query: 777 DVTQSTNVLLNTPALNAVFTPL 842
DV QST+VLL TPAL+AVFT L
Sbjct: 201 DVLQSTHVLLATPALDAVFTDL 222
>BC038234-1|AAH38234.1| 647|Homo sapiens phosphodiesterase 4A,
cAMP-specific (phosphodiesterase E2 dunce homolog,
Drosop protein.
Length = 647
Score = 192 bits (467), Expect = 2e-48
Identities = 95/202 (47%), Positives = 133/202 (65%), Gaps = 4/202 (1%)
Frame = +3
Query: 249 QFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKKKEKPR 428
QFKRMLN+EL+H SE S+SGNQ+SEYI +TFLDKQ E+++PS ++E ++ A + +
Sbjct: 22 QFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQ 81
Query: 429 HGGPATT----MSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVDI 596
P MSQI+G+K+ L H+NS +PR+GV+T +L++WG++I
Sbjct: 82 PPPPPVPHLQPMSQITGLKK-LMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNI 140
Query: 597 FRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHAA 776
F + D + GR LT + Y F R+LL +IP T + + +TL +HY D +HNSLHAA
Sbjct: 141 FCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHNSLHAA 200
Query: 777 DVTQSTNVLLNTPALNAVFTPL 842
DV QST+VLL TPAL+AVFT L
Sbjct: 201 DVLQSTHVLLATPALDAVFTDL 222
>BC019864-1|AAH19864.1| 647|Homo sapiens phosphodiesterase 4A,
cAMP-specific (phosphodiesterase E2 dunce homolog,
Drosop protein.
Length = 647
Score = 192 bits (467), Expect = 2e-48
Identities = 95/202 (47%), Positives = 133/202 (65%), Gaps = 4/202 (1%)
Frame = +3
Query: 249 QFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKKKEKPR 428
QFKRMLN+EL+H SE S+SGNQ+SEYI +TFLDKQ E+++PS ++E ++ A + +
Sbjct: 22 QFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQ 81
Query: 429 HGGPATT----MSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVDI 596
P MSQI+G+K+ L H+NS +PR+GV+T +L++WG++I
Sbjct: 82 PPPPPVPHLQPMSQITGLKK-LMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNI 140
Query: 597 FRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHAA 776
F + D + GR LT + Y F R+LL +IP T + + +TL +HY D +HNSLHAA
Sbjct: 141 FCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHNSLHAA 200
Query: 777 DVTQSTNVLLNTPALNAVFTPL 842
DV QST+VLL TPAL+AVFT L
Sbjct: 201 DVLQSTHVLLATPALDAVFTDL 222
>AF069491-3|AAC35013.1| 647|Homo sapiens cAMP specific
phosphodiesterase 4A variant RD1 protein.
Length = 647
Score = 192 bits (467), Expect = 2e-48
Identities = 95/202 (47%), Positives = 133/202 (65%), Gaps = 4/202 (1%)
Frame = +3
Query: 249 QFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKKKEKPR 428
QFKRMLN+EL+H SE S+SGNQ+SEYI +TFLDKQ E+++PS ++E ++ A + +
Sbjct: 22 QFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQ 81
Query: 429 HGGPATT----MSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVDI 596
P MSQI+G+K+ L H+NS +PR+GV+T +L++WG++I
Sbjct: 82 PPPPPVPHLQPMSQITGLKK-LMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNI 140
Query: 597 FRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHAA 776
F + D + GR LT + Y F R+LL +IP T + + +TL +HY D +HNSLHAA
Sbjct: 141 FCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHNSLHAA 200
Query: 777 DVTQSTNVLLNTPALNAVFTPL 842
DV QST+VLL TPAL+AVFT L
Sbjct: 201 DVLQSTHVLLATPALDAVFTDL 222
>U85048-1|AAB96381.1| 721|Homo sapiens cyclic AMP specific
phosphodiesterase protein.
Length = 721
Score = 189 bits (461), Expect = 1e-47
Identities = 96/203 (47%), Positives = 136/203 (66%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKRMLN+EL+H SE S+SGNQ+SEYI +TFLDKQ ++++PS +++ +K
Sbjct: 229 EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPS-----PTQKDREK 283
Query: 414 KEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVD 593
K+K + M+QISGVK+ L H++S + R+GV T + DL++WG++
Sbjct: 284 KKKQQ------LMTQISGVKK-LMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLN 336
Query: 594 IFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHA 773
IF + S RPLT + Y F R+LL T +I + TF+ + +TL +HY D +HNSLHA
Sbjct: 337 IFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHA 396
Query: 774 ADVTQSTNVLLNTPALNAVFTPL 842
ADV QST+VLL+TPAL+AVFT L
Sbjct: 397 ADVAQSTHVLLSTPALDAVFTDL 419
>M97515-1|AAA36426.1| 564|Homo sapiens phosphodiesterase protein.
Length = 564
Score = 189 bits (461), Expect = 1e-47
Identities = 96/203 (47%), Positives = 136/203 (66%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKRMLN+EL+H SE S+SGNQ+SEYI +TFLDKQ ++++PS +++ +K
Sbjct: 72 EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPS-----PTQKDREK 126
Query: 414 KEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVD 593
K+K + M+QISGVK+ L H++S + R+GV T + DL++WG++
Sbjct: 127 KKKQQ------LMTQISGVKK-LMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLN 179
Query: 594 IFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHA 773
IF + S RPLT + Y F R+LL T +I + TF+ + +TL +HY D +HNSLHA
Sbjct: 180 IFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHA 239
Query: 774 ADVTQSTNVLLNTPALNAVFTPL 842
ADV QST+VLL+TPAL+AVFT L
Sbjct: 240 ADVAQSTHVLLSTPALDAVFTDL 262
>L20971-1|AAA03593.1| 564|Homo sapiens phosphodiesterase protein.
Length = 564
Score = 189 bits (461), Expect = 1e-47
Identities = 96/203 (47%), Positives = 136/203 (66%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKRMLN+EL+H SE S+SGNQ+SEYI +TFLDKQ ++++PS +++ +K
Sbjct: 72 EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPS-----PTQKDREK 126
Query: 414 KEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVD 593
K+K + M+QISGVK+ L H++S + R+GV T + DL++WG++
Sbjct: 127 KKKQQ------LMTQISGVKK-LMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLN 179
Query: 594 IFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHA 773
IF + S RPLT + Y F R+LL T +I + TF+ + +TL +HY D +HNSLHA
Sbjct: 180 IFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHA 239
Query: 774 ADVTQSTNVLLNTPALNAVFTPL 842
ADV QST+VLL+TPAL+AVFT L
Sbjct: 240 ADVAQSTHVLLSTPALDAVFTDL 262
>L20966-1|AAA03589.1| 736|Homo sapiens phosphodiesterase protein.
Length = 736
Score = 189 bits (461), Expect = 1e-47
Identities = 96/203 (47%), Positives = 136/203 (66%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKRMLN+EL+H SE S+SGNQ+SEYI +TFLDKQ ++++PS +++ +K
Sbjct: 244 EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPS-----PTQKDREK 298
Query: 414 KEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVD 593
K+K + M+QISGVK+ L H++S + R+GV T + DL++WG++
Sbjct: 299 KKKQQ------LMTQISGVKK-LMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLN 351
Query: 594 IFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHA 773
IF + S RPLT + Y F R+LL T +I + TF+ + +TL +HY D +HNSLHA
Sbjct: 352 IFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHA 411
Query: 774 ADVTQSTNVLLNTPALNAVFTPL 842
ADV QST+VLL+TPAL+AVFT L
Sbjct: 412 ADVAQSTHVLLSTPALDAVFTDL 434
>L12686-1|AAA35643.1| 606|Homo sapiens 3',5'-cyclic AMP
phosphodiesterase protein.
Length = 606
Score = 189 bits (461), Expect = 1e-47
Identities = 96/203 (47%), Positives = 136/203 (66%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKRMLN+EL+H SE S+SGNQ+SEYI +TFLDKQ ++++PS +++ +K
Sbjct: 114 EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPS-----PTQKDREK 168
Query: 414 KEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVD 593
K+K + M+QISGVK+ L H++S + R+GV T + DL++WG++
Sbjct: 169 KKKQQ------LMTQISGVKK-LMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLN 221
Query: 594 IFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHA 773
IF + S RPLT + Y F R+LL T +I + TF+ + +TL +HY D +HNSLHA
Sbjct: 222 IFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHA 281
Query: 774 ADVTQSTNVLLNTPALNAVFTPL 842
ADV QST+VLL+TPAL+AVFT L
Sbjct: 282 ADVAQSTHVLLSTPALDAVFTDL 304
>BC105040-1|AAI05041.1| 736|Homo sapiens phosphodiesterase 4B,
cAMP-specific (phosphodiesterase E4 dunce homolog,
Drosop protein.
Length = 736
Score = 189 bits (461), Expect = 1e-47
Identities = 96/203 (47%), Positives = 136/203 (66%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKRMLN+EL+H SE S+SGNQ+SEYI +TFLDKQ ++++PS +++ +K
Sbjct: 244 EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPS-----PTQKDREK 298
Query: 414 KEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVD 593
K+K + M+QISGVK+ L H++S + R+GV T + DL++WG++
Sbjct: 299 KKKQQ------LMTQISGVKK-LMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLN 351
Query: 594 IFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHA 773
IF + S RPLT + Y F R+LL T +I + TF+ + +TL +HY D +HNSLHA
Sbjct: 352 IFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHA 411
Query: 774 ADVTQSTNVLLNTPALNAVFTPL 842
ADV QST+VLL+TPAL+AVFT L
Sbjct: 412 ADVAQSTHVLLSTPALDAVFTDL 434
>BC101480-1|AAI01481.1| 736|Homo sapiens phosphodiesterase 4B,
cAMP-specific (phosphodiesterase E4 dunce homolog,
Drosop protein.
Length = 736
Score = 189 bits (461), Expect = 1e-47
Identities = 96/203 (47%), Positives = 136/203 (66%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKRMLN+EL+H SE S+SGNQ+SEYI +TFLDKQ ++++PS +++ +K
Sbjct: 244 EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPS-----PTQKDREK 298
Query: 414 KEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVD 593
K+K + M+QISGVK+ L H++S + R+GV T + DL++WG++
Sbjct: 299 KKKQQ------LMTQISGVKK-LMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLN 351
Query: 594 IFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHA 773
IF + S RPLT + Y F R+LL T +I + TF+ + +TL +HY D +HNSLHA
Sbjct: 352 IFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHA 411
Query: 774 ADVTQSTNVLLNTPALNAVFTPL 842
ADV QST+VLL+TPAL+AVFT L
Sbjct: 412 ADVAQSTHVLLSTPALDAVFTDL 434
>AL592285-3|CAH70628.1| 721|Homo sapiens phosphodiesterase 4B,
cAMP-specific (phosphodiesterase E4 dunce homolog,
Drosop protein.
Length = 721
Score = 189 bits (461), Expect = 1e-47
Identities = 96/203 (47%), Positives = 136/203 (66%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKRMLN+EL+H SE S+SGNQ+SEYI +TFLDKQ ++++PS +++ +K
Sbjct: 229 EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPS-----PTQKDREK 283
Query: 414 KEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVD 593
K+K + M+QISGVK+ L H++S + R+GV T + DL++WG++
Sbjct: 284 KKKQQ------LMTQISGVKK-LMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLN 336
Query: 594 IFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHA 773
IF + S RPLT + Y F R+LL T +I + TF+ + +TL +HY D +HNSLHA
Sbjct: 337 IFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHA 396
Query: 774 ADVTQSTNVLLNTPALNAVFTPL 842
ADV QST+VLL+TPAL+AVFT L
Sbjct: 397 ADVAQSTHVLLSTPALDAVFTDL 419
>AL592285-1|CAH70626.1| 736|Homo sapiens phosphodiesterase 4B,
cAMP-specific (phosphodiesterase E4 dunce homolog,
Drosop protein.
Length = 736
Score = 189 bits (461), Expect = 1e-47
Identities = 96/203 (47%), Positives = 136/203 (66%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKRMLN+EL+H SE S+SGNQ+SEYI +TFLDKQ ++++PS +++ +K
Sbjct: 244 EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPS-----PTQKDREK 298
Query: 414 KEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVD 593
K+K + M+QISGVK+ L H++S + R+GV T + DL++WG++
Sbjct: 299 KKKQQ------LMTQISGVKK-LMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLN 351
Query: 594 IFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHA 773
IF + S RPLT + Y F R+LL T +I + TF+ + +TL +HY D +HNSLHA
Sbjct: 352 IFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHA 411
Query: 774 ADVTQSTNVLLNTPALNAVFTPL 842
ADV QST+VLL+TPAL+AVFT L
Sbjct: 412 ADVAQSTHVLLSTPALDAVFTDL 434
>AL359701-3|CAI23101.1| 721|Homo sapiens phosphodiesterase 4B,
cAMP-specific (phosphodiesterase E4 dunce homolog,
Drosop protein.
Length = 721
Score = 189 bits (461), Expect = 1e-47
Identities = 96/203 (47%), Positives = 136/203 (66%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKRMLN+EL+H SE S+SGNQ+SEYI +TFLDKQ ++++PS +++ +K
Sbjct: 229 EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPS-----PTQKDREK 283
Query: 414 KEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVD 593
K+K + M+QISGVK+ L H++S + R+GV T + DL++WG++
Sbjct: 284 KKKQQ------LMTQISGVKK-LMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLN 336
Query: 594 IFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHA 773
IF + S RPLT + Y F R+LL T +I + TF+ + +TL +HY D +HNSLHA
Sbjct: 337 IFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHA 396
Query: 774 ADVTQSTNVLLNTPALNAVFTPL 842
ADV QST+VLL+TPAL+AVFT L
Sbjct: 397 ADVAQSTHVLLSTPALDAVFTDL 419
>AL359701-2|CAI23100.1| 564|Homo sapiens phosphodiesterase 4B,
cAMP-specific (phosphodiesterase E4 dunce homolog,
Drosop protein.
Length = 564
Score = 189 bits (461), Expect = 1e-47
Identities = 96/203 (47%), Positives = 136/203 (66%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKRMLN+EL+H SE S+SGNQ+SEYI +TFLDKQ ++++PS +++ +K
Sbjct: 72 EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPS-----PTQKDREK 126
Query: 414 KEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVD 593
K+K + M+QISGVK+ L H++S + R+GV T + DL++WG++
Sbjct: 127 KKKQQ------LMTQISGVKK-LMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLN 179
Query: 594 IFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHA 773
IF + S RPLT + Y F R+LL T +I + TF+ + +TL +HY D +HNSLHA
Sbjct: 180 IFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHA 239
Query: 774 ADVTQSTNVLLNTPALNAVFTPL 842
ADV QST+VLL+TPAL+AVFT L
Sbjct: 240 ADVAQSTHVLLSTPALDAVFTDL 262
>AL359701-1|CAI23099.1| 736|Homo sapiens phosphodiesterase 4B,
cAMP-specific (phosphodiesterase E4 dunce homolog,
Drosop protein.
Length = 736
Score = 189 bits (461), Expect = 1e-47
Identities = 96/203 (47%), Positives = 136/203 (66%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKRMLN+EL+H SE S+SGNQ+SEYI +TFLDKQ ++++PS +++ +K
Sbjct: 244 EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPS-----PTQKDREK 298
Query: 414 KEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVD 593
K+K + M+QISGVK+ L H++S + R+GV T + DL++WG++
Sbjct: 299 KKKQQ------LMTQISGVKK-LMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLN 351
Query: 594 IFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHA 773
IF + S RPLT + Y F R+LL T +I + TF+ + +TL +HY D +HNSLHA
Sbjct: 352 IFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHA 411
Query: 774 ADVTQSTNVLLNTPALNAVFTPL 842
ADV QST+VLL+TPAL+AVFT L
Sbjct: 412 ADVAQSTHVLLSTPALDAVFTDL 434
>AL357273-3|CAH73004.1| 721|Homo sapiens phosphodiesterase 4B,
cAMP-specific (phosphodiesterase E4 dunce homolog,
Drosop protein.
Length = 721
Score = 189 bits (461), Expect = 1e-47
Identities = 96/203 (47%), Positives = 136/203 (66%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKRMLN+EL+H SE S+SGNQ+SEYI +TFLDKQ ++++PS +++ +K
Sbjct: 229 EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPS-----PTQKDREK 283
Query: 414 KEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVD 593
K+K + M+QISGVK+ L H++S + R+GV T + DL++WG++
Sbjct: 284 KKKQQ------LMTQISGVKK-LMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLN 336
Query: 594 IFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHA 773
IF + S RPLT + Y F R+LL T +I + TF+ + +TL +HY D +HNSLHA
Sbjct: 337 IFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHA 396
Query: 774 ADVTQSTNVLLNTPALNAVFTPL 842
ADV QST+VLL+TPAL+AVFT L
Sbjct: 397 ADVAQSTHVLLSTPALDAVFTDL 419
>AL357273-1|CAH73002.1| 736|Homo sapiens phosphodiesterase 4B,
cAMP-specific (phosphodiesterase E4 dunce homolog,
Drosop protein.
Length = 736
Score = 189 bits (461), Expect = 1e-47
Identities = 96/203 (47%), Positives = 136/203 (66%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKRMLN+EL+H SE S+SGNQ+SEYI +TFLDKQ ++++PS +++ +K
Sbjct: 244 EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPS-----PTQKDREK 298
Query: 414 KEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVD 593
K+K + M+QISGVK+ L H++S + R+GV T + DL++WG++
Sbjct: 299 KKKQQ------LMTQISGVKK-LMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLN 351
Query: 594 IFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHA 773
IF + S RPLT + Y F R+LL T +I + TF+ + +TL +HY D +HNSLHA
Sbjct: 352 IFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHA 411
Query: 774 ADVTQSTNVLLNTPALNAVFTPL 842
ADV QST+VLL+TPAL+AVFT L
Sbjct: 412 ADVAQSTHVLLSTPALDAVFTDL 434
>AL109926-4|CAI21751.1| 721|Homo sapiens phosphodiesterase 4B,
cAMP-specific (phosphodiesterase E4 dunce homolog,
Drosop protein.
Length = 721
Score = 189 bits (461), Expect = 1e-47
Identities = 96/203 (47%), Positives = 136/203 (66%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKRMLN+EL+H SE S+SGNQ+SEYI +TFLDKQ ++++PS +++ +K
Sbjct: 229 EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPS-----PTQKDREK 283
Query: 414 KEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVD 593
K+K + M+QISGVK+ L H++S + R+GV T + DL++WG++
Sbjct: 284 KKKQQ------LMTQISGVKK-LMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLN 336
Query: 594 IFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHA 773
IF + S RPLT + Y F R+LL T +I + TF+ + +TL +HY D +HNSLHA
Sbjct: 337 IFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHA 396
Query: 774 ADVTQSTNVLLNTPALNAVFTPL 842
ADV QST+VLL+TPAL+AVFT L
Sbjct: 397 ADVAQSTHVLLSTPALDAVFTDL 419
>AL109926-3|CAI21750.1| 564|Homo sapiens phosphodiesterase 4B,
cAMP-specific (phosphodiesterase E4 dunce homolog,
Drosop protein.
Length = 564
Score = 189 bits (461), Expect = 1e-47
Identities = 96/203 (47%), Positives = 136/203 (66%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKRMLN+EL+H SE S+SGNQ+SEYI +TFLDKQ ++++PS +++ +K
Sbjct: 72 EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPS-----PTQKDREK 126
Query: 414 KEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVD 593
K+K + M+QISGVK+ L H++S + R+GV T + DL++WG++
Sbjct: 127 KKKQQ------LMTQISGVKK-LMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLN 179
Query: 594 IFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHA 773
IF + S RPLT + Y F R+LL T +I + TF+ + +TL +HY D +HNSLHA
Sbjct: 180 IFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHA 239
Query: 774 ADVTQSTNVLLNTPALNAVFTPL 842
ADV QST+VLL+TPAL+AVFT L
Sbjct: 240 ADVAQSTHVLLSTPALDAVFTDL 262
>AL109926-2|CAI21749.1| 736|Homo sapiens phosphodiesterase 4B,
cAMP-specific (phosphodiesterase E4 dunce homolog,
Drosop protein.
Length = 736
Score = 189 bits (461), Expect = 1e-47
Identities = 96/203 (47%), Positives = 136/203 (66%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKRMLN+EL+H SE S+SGNQ+SEYI +TFLDKQ ++++PS +++ +K
Sbjct: 244 EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPS-----PTQKDREK 298
Query: 414 KEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVD 593
K+K + M+QISGVK+ L H++S + R+GV T + DL++WG++
Sbjct: 299 KKKQQ------LMTQISGVKK-LMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLN 351
Query: 594 IFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHA 773
IF + S RPLT + Y F R+LL T +I + TF+ + +TL +HY D +HNSLHA
Sbjct: 352 IFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHA 411
Query: 774 ADVTQSTNVLLNTPALNAVFTPL 842
ADV QST+VLL+TPAL+AVFT L
Sbjct: 412 ADVAQSTHVLLSTPALDAVFTDL 434
>AB209081-1|BAD92318.1| 726|Homo sapiens phosphodiesterase 4B,
cAMP-specific (phosphodiesterase E4 dunce homolog,
Drosop protein.
Length = 726
Score = 189 bits (461), Expect = 1e-47
Identities = 96/203 (47%), Positives = 136/203 (66%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKRMLN+EL+H SE S+SGNQ+SEYI +TFLDKQ ++++PS +++ +K
Sbjct: 234 EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPS-----PTQKDREK 288
Query: 414 KEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVD 593
K+K + M+QISGVK+ L H++S + R+GV T + DL++WG++
Sbjct: 289 KKKQQ------LMTQISGVKK-LMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLN 341
Query: 594 IFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHA 773
IF + S RPLT + Y F R+LL T +I + TF+ + +TL +HY D +HNSLHA
Sbjct: 342 IFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHA 401
Query: 774 ADVTQSTNVLLNTPALNAVFTPL 842
ADV QST+VLL+TPAL+AVFT L
Sbjct: 402 ADVAQSTHVLLSTPALDAVFTDL 424
>EF595686-1|ABQ85407.1| 503|Homo sapiens cAMP-specific
phosphodiesterase-4 B isoform protein.
Length = 503
Score = 189 bits (460), Expect = 1e-47
Identities = 95/205 (46%), Positives = 137/205 (66%)
Frame = +3
Query: 228 SIEMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGA 407
S+ + +FKRMLN+EL+H SE S+SGNQ+SEYI +TFLDKQ ++++PS +++
Sbjct: 9 SVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPS-----PTQKDR 63
Query: 408 KKKEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWG 587
+KK+K + M+QISGVK+ L H++S + R+GV T + DL++WG
Sbjct: 64 EKKKKQQ------LMTQISGVKK-LMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWG 116
Query: 588 VDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSL 767
++IF + S RPLT + Y F R+LL T +I + TF+ + +TL +HY D +HNSL
Sbjct: 117 LNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSL 176
Query: 768 HAADVTQSTNVLLNTPALNAVFTPL 842
HAADV QST+VLL+TPAL+AVFT L
Sbjct: 177 HAADVAQSTHVLLSTPALDAVFTDL 201
>Z46632-1|CAA86601.1| 712|Homo sapiens 3',5'-cyclic AMP
phosphodiesterase protein.
Length = 712
Score = 180 bits (437), Expect = 8e-45
Identities = 94/203 (46%), Positives = 128/203 (63%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKR+LN+EL+H SE+S+SGNQ+SEYI TFLD+Q E++LP + EE +
Sbjct: 231 EMASNKFKRILNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQ----- 285
Query: 414 KEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVD 593
MS+ISG+ L H+ S + VPR+GV+T D ++WG+D
Sbjct: 286 -----------PMSRISGL-HGLCHSASLSSATVPRFGVQTDQEEQLAKELEDTNKWGLD 333
Query: 594 IFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHA 773
+F++ D+S RPLTA+ ++ F R+LL T QIPA T + + L HY + +HNSLHA
Sbjct: 334 VFKVADVSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHA 393
Query: 774 ADVTQSTNVLLNTPALNAVFTPL 842
ADV QST+VLL TPAL AVFT L
Sbjct: 394 ADVAQSTHVLLATPALEAVFTDL 416
>AF157816-3|AAD47055.1| 606|Homo sapiens cAMP specific
phosphodiesterase PDE4C2 variant protein.
Length = 606
Score = 179 bits (436), Expect = 1e-44
Identities = 94/203 (46%), Positives = 128/203 (63%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKR+LN+EL+H SE+S+SGNQ+SEYI TFLD+Q E++LP + EE +
Sbjct: 125 EMASNKFKRILNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQ----- 179
Query: 414 KEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVD 593
MS+ISG+ L H+ S + VPR+GV+T D ++WG+D
Sbjct: 180 -----------PMSRISGL-HGLCHSASLSSATVPRFGVQTDQEEQLAKELEDTNKWGLD 227
Query: 594 IFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHA 773
+F++ +LS RPLTA+ ++ F R+LL T QIPA T + + L HY + +HNSLHA
Sbjct: 228 VFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHA 287
Query: 774 ADVTQSTNVLLNTPALNAVFTPL 842
ADV QST+VLL TPAL AVFT L
Sbjct: 288 ADVAQSTHVLLATPALEAVFTDL 310
>AF157816-2|AAD47054.1| 680|Homo sapiens cAMP specific
phosphodiesterase PDE4C3 variant protein.
Length = 680
Score = 179 bits (436), Expect = 1e-44
Identities = 94/203 (46%), Positives = 128/203 (63%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKR+LN+EL+H SE+S+SGNQ+SEYI TFLD+Q E++LP + EE +
Sbjct: 199 EMASNKFKRILNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQ----- 253
Query: 414 KEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVD 593
MS+ISG+ L H+ S + VPR+GV+T D ++WG+D
Sbjct: 254 -----------PMSRISGL-HGLCHSASLSSATVPRFGVQTDQEEQLAKELEDTNKWGLD 301
Query: 594 IFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHA 773
+F++ +LS RPLTA+ ++ F R+LL T QIPA T + + L HY + +HNSLHA
Sbjct: 302 VFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHA 361
Query: 774 ADVTQSTNVLLNTPALNAVFTPL 842
ADV QST+VLL TPAL AVFT L
Sbjct: 362 ADVAQSTHVLLATPALEAVFTDL 384
>AF157816-1|AAD47053.1| 712|Homo sapiens cAMP specific
phosphodiesterase PDE4C1 variant protein.
Length = 712
Score = 179 bits (436), Expect = 1e-44
Identities = 94/203 (46%), Positives = 128/203 (63%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKR+LN+EL+H SE+S+SGNQ+SEYI TFLD+Q E++LP + EE +
Sbjct: 231 EMASNKFKRILNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQ----- 285
Query: 414 KEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVD 593
MS+ISG+ L H+ S + VPR+GV+T D ++WG+D
Sbjct: 286 -----------PMSRISGL-HGLCHSASLSSATVPRFGVQTDQEEQLAKELEDTNKWGLD 333
Query: 594 IFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHA 773
+F++ +LS RPLTA+ ++ F R+LL T QIPA T + + L HY + +HNSLHA
Sbjct: 334 VFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHA 393
Query: 774 ADVTQSTNVLLNTPALNAVFTPL 842
ADV QST+VLL TPAL AVFT L
Sbjct: 394 ADVAQSTHVLLATPALEAVFTDL 416
>AC005759-2|AAC83047.1| 710|Homo sapiens CN4C_HUMAN protein.
Length = 710
Score = 179 bits (436), Expect = 1e-44
Identities = 94/203 (46%), Positives = 128/203 (63%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKR+LN+EL+H SE+S+SGNQ+SEYI TFLD+Q E++LP + EE +
Sbjct: 231 EMASNKFKRILNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQ----- 285
Query: 414 KEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVD 593
MS+ISG+ L H+ S + VPR+GV+T D ++WG+D
Sbjct: 286 -----------PMSRISGL-HGLCHSASLSSATVPRFGVQTDQEEQLAKELEDTNKWGLD 333
Query: 594 IFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHA 773
+F++ +LS RPLTA+ ++ F R+LL T QIPA T + + L HY + +HNSLHA
Sbjct: 334 VFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHA 393
Query: 774 ADVTQSTNVLLNTPALNAVFTPL 842
ADV QST+VLL TPAL AVFT L
Sbjct: 394 ADVAQSTHVLLATPALEAVFTDL 416
>AC005759-1|AAC83050.1| 782|Homo sapiens PDE4C-791 protein.
Length = 782
Score = 179 bits (436), Expect = 1e-44
Identities = 94/203 (46%), Positives = 128/203 (63%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKR+LN+EL+H SE+S+SGNQ+SEYI TFLD+Q E++LP + EE +
Sbjct: 301 EMASNKFKRILNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQ----- 355
Query: 414 KEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVD 593
MS+ISG+ L H+ S + VPR+GV+T D ++WG+D
Sbjct: 356 -----------PMSRISGL-HGLCHSASLSSATVPRFGVQTDQEEQLAKELEDTNKWGLD 403
Query: 594 IFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHA 773
+F++ +LS RPLTA+ ++ F R+LL T QIPA T + + L HY + +HNSLHA
Sbjct: 404 VFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHA 463
Query: 774 ADVTQSTNVLLNTPALNAVFTPL 842
ADV QST+VLL TPAL AVFT L
Sbjct: 464 ADVAQSTHVLLATPALEAVFTDL 486
>U66348-1|AAB96877.1| 518|Homo sapiens PDE4C-delta54 protein.
Length = 518
Score = 179 bits (435), Expect = 1e-44
Identities = 93/198 (46%), Positives = 126/198 (63%)
Frame = +3
Query: 249 QFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKKKEKPR 428
QFKR+LN+EL+H SE+S+SGNQ+SEYI TFLD+Q E++LP + EE +
Sbjct: 42 QFKRILNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQ---------- 91
Query: 429 HGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVDIFRIG 608
MS+ISG+ L H+ S + VPR+GV+T D ++WG+D+F++
Sbjct: 92 ------PMSRISGL-HGLCHSASLSSATVPRFGVQTDQEEQLAKELEDTNKWGLDVFKVA 144
Query: 609 DLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHAADVTQ 788
+LS RPLTA+ ++ F R+LL T QIPA T + + L HY + +HNSLHAADV Q
Sbjct: 145 ELSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQ 204
Query: 789 STNVLLNTPALNAVFTPL 842
ST+VLL TPAL AVFT L
Sbjct: 205 STHVLLATPALEAVFTDL 222
>AC005759-3|AAC83051.1| 518|Homo sapiens PDE4C-delta54 protein.
Length = 518
Score = 179 bits (435), Expect = 1e-44
Identities = 93/198 (46%), Positives = 126/198 (63%)
Frame = +3
Query: 249 QFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKKKEKPR 428
QFKR+LN+EL+H SE+S+SGNQ+SEYI TFLD+Q E++LP + EE +
Sbjct: 42 QFKRILNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQ---------- 91
Query: 429 HGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVDIFRIG 608
MS+ISG+ L H+ S + VPR+GV+T D ++WG+D+F++
Sbjct: 92 ------PMSRISGL-HGLCHSASLSSATVPRFGVQTDQEEQLAKELEDTNKWGLDVFKVA 144
Query: 609 DLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHAADVTQ 788
+LS RPLTA+ ++ F R+LL T QIPA T + + L HY + +HNSLHAADV Q
Sbjct: 145 ELSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQ 204
Query: 789 STNVLLNTPALNAVFTPL 842
ST+VLL TPAL AVFT L
Sbjct: 205 STHVLLATPALEAVFTDL 222
>U88713-1|AAC51916.1| 700|Homo sapiens phosphodiesterase 4C
protein.
Length = 700
Score = 177 bits (432), Expect = 3e-44
Identities = 93/203 (45%), Positives = 128/203 (63%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKR+LN+EL+H SE+S+SGNQ+SEYI TFLD+Q E++LP + EE +
Sbjct: 219 EMASNKFKRILNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQ----- 273
Query: 414 KEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVD 593
MS+ISG+ L H+ S + VPR+GV+T D ++WG+D
Sbjct: 274 -----------PMSRISGL-HGLCHSASLSSATVPRFGVQTDQEEQLAKELEDTNKWGLD 321
Query: 594 IFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHA 773
+F++ +LS +PLTA+ ++ F R+LL T QIPA T + + L HY + +HNSLHA
Sbjct: 322 VFKVAELSGNQPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHA 381
Query: 774 ADVTQSTNVLLNTPALNAVFTPL 842
ADV QST+VLL TPAL AVFT L
Sbjct: 382 ADVAQSTHVLLATPALEAVFTDL 404
>U88712-1|AAC51915.1| 606|Homo sapiens phosphodiesterase 4C
protein.
Length = 606
Score = 177 bits (432), Expect = 3e-44
Identities = 93/203 (45%), Positives = 128/203 (63%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKR+LN+EL+H SE+S+SGNQ+SEYI TFLD+Q E++LP + EE +
Sbjct: 125 EMASNKFKRILNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQ----- 179
Query: 414 KEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVD 593
MS+ISG+ L H+ S + VPR+GV+T D ++WG+D
Sbjct: 180 -----------PMSRISGL-HGLCHSASLSSATVPRFGVQTDQEEQLAKELEDTNKWGLD 227
Query: 594 IFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHA 773
+F++ +LS +PLTA+ ++ F R+LL T QIPA T + + L HY + +HNSLHA
Sbjct: 228 VFKVAELSGNQPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHA 287
Query: 774 ADVTQSTNVLLNTPALNAVFTPL 842
ADV QST+VLL TPAL AVFT L
Sbjct: 288 ADVAQSTHVLLATPALEAVFTDL 310
>U66346-1|AAB96875.1| 791|Homo sapiens PDE4C-791 protein.
Length = 791
Score = 177 bits (432), Expect = 3e-44
Identities = 93/203 (45%), Positives = 128/203 (63%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKR+LN+EL+H SE+S+SGNQ+SEYI TFLD+Q E++LP + EE +
Sbjct: 310 EMASNKFKRILNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQ----- 364
Query: 414 KEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVD 593
MS+ISG+ L H+ S + VPR+GV+T D ++WG+D
Sbjct: 365 -----------PMSRISGL-HGLCHSASLSSATVPRFGVQTDQEEQLAKELEDTNKWGLD 412
Query: 594 IFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHA 773
+F++ +LS +PLTA+ ++ F R+LL T QIPA T + + L HY + +HNSLHA
Sbjct: 413 VFKVAELSGNQPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHA 472
Query: 774 ADVTQSTNVLLNTPALNAVFTPL 842
ADV QST+VLL TPAL AVFT L
Sbjct: 473 ADVAQSTHVLLATPALEAVFTDL 495
>BC109068-1|AAI09069.1| 549|Homo sapiens PDE4C protein protein.
Length = 549
Score = 177 bits (432), Expect = 3e-44
Identities = 93/203 (45%), Positives = 128/203 (63%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKR+LN+EL+H SE+S+SGNQ+SEYI TFLD+Q E++LP + EE +
Sbjct: 68 EMASNKFKRILNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQ----- 122
Query: 414 KEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVD 593
MS+ISG+ L H+ S + VPR+GV+T D ++WG+D
Sbjct: 123 -----------PMSRISGL-HGLCHSASLSSATVPRFGVQTDQEEQLAKELEDTNKWGLD 170
Query: 594 IFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHA 773
+F++ +LS +PLTA+ ++ F R+LL T QIPA T + + L HY + +HNSLHA
Sbjct: 171 VFKVAELSGNQPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHA 230
Query: 774 ADVTQSTNVLLNTPALNAVFTPL 842
ADV QST+VLL TPAL AVFT L
Sbjct: 231 ADVAQSTHVLLATPALEAVFTDL 253
>BC109067-1|AAI09068.1| 481|Homo sapiens PDE4C protein protein.
Length = 481
Score = 177 bits (431), Expect = 4e-44
Identities = 92/198 (46%), Positives = 126/198 (63%)
Frame = +3
Query: 249 QFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKKKEKPR 428
+FKR+LN+EL+H SE+S+SGNQ+SEYI TFLD+Q E++LP + EE +
Sbjct: 5 KFKRILNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQ---------- 54
Query: 429 HGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVDIFRIG 608
MS+ISG+ L H+ S + VPR+GV+T D ++WG+D+F++
Sbjct: 55 ------PMSRISGL-HGLCHSASLSSATVPRFGVQTDQEEQLAKELEDTNKWGLDVFKVA 107
Query: 609 DLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHAADVTQ 788
+LS RPLTA+ ++ F R+LL T QIPA T + + L HY + +HNSLHAADV Q
Sbjct: 108 ELSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQ 167
Query: 789 STNVLLNTPALNAVFTPL 842
ST+VLL TPAL AVFT L
Sbjct: 168 STHVLLATPALEAVFTDL 185
>AC005759-5|AAC83049.1| 426|Homo sapiens PDE4C-426 protein.
Length = 426
Score = 129 bits (311), Expect = 1e-29
Identities = 63/131 (48%), Positives = 85/131 (64%)
Frame = +3
Query: 450 MSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVDIFRIGDLSCGRP 629
MS+ISG+ L H+ S + VPR+GV+T D ++WG+D+F++ +LS RP
Sbjct: 1 MSRISGL-HGLCHSASLSSATVPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRP 59
Query: 630 LTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHAADVTQSTNVLLN 809
LTA+ ++ F R+LL T QIPA T + + L HY + +HNSLHAADV QST+VLL
Sbjct: 60 LTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLA 119
Query: 810 TPALNAVFTPL 842
TPAL AVFT L
Sbjct: 120 TPALEAVFTDL 130
>U66347-1|AAB96876.1| 426|Homo sapiens PDE4C-426 protein.
Length = 426
Score = 127 bits (307), Expect = 4e-29
Identities = 62/131 (47%), Positives = 85/131 (64%)
Frame = +3
Query: 450 MSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVDIFRIGDLSCGRP 629
MS+ISG+ L H+ S + VPR+GV+T D ++WG+D+F++ +LS +P
Sbjct: 1 MSRISGL-HGLCHSASLSSATVPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNQP 59
Query: 630 LTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHNSLHAADVTQSTNVLLN 809
LTA+ ++ F R+LL T QIPA T + + L HY + +HNSLHAADV QST+VLL
Sbjct: 60 LTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLA 119
Query: 810 TPALNAVFTPL 842
TPAL AVFT L
Sbjct: 120 TPALEAVFTDL 130
>U79571-1|AAC51928.1| 205|Homo sapiens 3'5' cyclic nucleotide
phosphodiesterase 4D splice variant 1 protein.
Length = 205
Score = 126 bits (303), Expect = 1e-28
Identities = 64/141 (45%), Positives = 94/141 (66%)
Frame = +3
Query: 234 EMLHFQFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKK 413
EM +FKRMLN+EL+H SE S+SGNQ+SE+I +TFLDKQ E+++PS +++ +K
Sbjct: 78 EMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPS-----PTQKEKEK 132
Query: 414 KEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVD 593
K++P MSQISGVK+ L H++S T +PR+GV+T D+++WG+
Sbjct: 133 KKRP--------MSQISGVKK-LMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLH 183
Query: 594 IFRIGDLSCGRPLTAVAYTAF 656
+FRI +LS RPLT + +T F
Sbjct: 184 VFRIAELSGNRPLTVIMHTIF 204
>AC005759-4|AAC83048.1| 427|Homo sapiens PDE4C-delta109 protein.
Length = 427
Score = 114 bits (275), Expect = 3e-25
Identities = 67/169 (39%), Positives = 99/169 (58%)
Frame = +3
Query: 249 QFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKKKEKPR 428
QFKR+LN+EL+H SE+S+SGNQ+SEYI TFLD+Q E++LP + EE +
Sbjct: 6 QFKRILNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQ---------- 55
Query: 429 HGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVDIFRIG 608
MS+ISG+ L H+ S + VPR+GV+T D ++WG+D+F++
Sbjct: 56 ------PMSRISGL-HGLCHSASLSSATVPRFGVQTDQEEQLAKELEDTNKWGLDVFKVA 108
Query: 609 DLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPF 755
+LS RPLTA+ ++ F + + T L+I A F A A+ +H N F
Sbjct: 109 ELSGNRPLTAIIFSIF--QAVFTDLEILAALF-ASAIHDVDHPGVSNQF 154
>U66349-1|AAB96878.1| 427|Homo sapiens PDE4C-delta109 protein.
Length = 427
Score = 113 bits (271), Expect = 1e-24
Identities = 66/169 (39%), Positives = 99/169 (58%)
Frame = +3
Query: 249 QFKRMLNKELSHFSESSKSGNQISEYICSTFLDKQQELDLPSLQVEETSERGAKKKEKPR 428
QFKR+LN+EL+H SE+S+SGNQ+SEYI TFLD+Q E++LP + EE +
Sbjct: 6 QFKRILNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQ---------- 55
Query: 429 HGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWGVDIFRIG 608
MS+ISG+ L H+ S + VPR+GV+T D ++WG+D+F++
Sbjct: 56 ------PMSRISGL-HGLCHSASLSSATVPRFGVQTDQEEQLAKELEDTNKWGLDVFKVA 108
Query: 609 DLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPF 755
+LS +PLTA+ ++ F + + T L+I A F A A+ +H N F
Sbjct: 109 ELSGNQPLTAIIFSIF--QAVFTDLEILAALF-ASAIHDVDHPGVSNQF 154
>U18088-1|AAA98540.1| 323|Homo sapiens 3',5'-cyclic AMP
phosphodiesterase HSPDE4A7A protein.
Length = 323
Score = 102 bits (244), Expect = 2e-21
Identities = 47/91 (51%), Positives = 64/91 (70%)
Frame = +3
Query: 570 DLDRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDN 749
+L++WG++IF + D + GR LT + Y F R+LL +IP T + + +TL +HY D
Sbjct: 37 NLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADV 96
Query: 750 PFHNSLHAADVTQSTNVLLNTPALNAVFTPL 842
+HNSLHAADV QST+VLL TPAL+AVFT L
Sbjct: 97 AYHNSLHAADVLQSTHVLLATPALDAVFTDL 127
>AF069491-4|AAC35014.1| 323|Homo sapiens cAMP specific
phosphodiesterase 4A variant 2EL protein.
Length = 323
Score = 102 bits (244), Expect = 2e-21
Identities = 47/91 (51%), Positives = 64/91 (70%)
Frame = +3
Query: 570 DLDRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDN 749
+L++WG++IF + D + GR LT + Y F R+LL +IP T + + +TL +HY D
Sbjct: 37 NLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADV 96
Query: 750 PFHNSLHAADVTQSTNVLLNTPALNAVFTPL 842
+HNSLHAADV QST+VLL TPAL+AVFT L
Sbjct: 97 AYHNSLHAADVLQSTHVLLATPALDAVFTDL 127
>U40370-1|AAC50436.1| 535|Homo sapiens 3',5' cyclic nucleotide
phosphodiesterase protein.
Length = 535
Score = 63.3 bits (147), Expect = 1e-09
Identities = 30/83 (36%), Positives = 48/83 (57%), Gaps = 2/83 (2%)
Frame = +3
Query: 570 DLDRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIR-D 746
D+D+W D+F + + S L + Y FT +L+ +IP + FA L Y +
Sbjct: 156 DVDKWSFDVFALNEASGEHSLKFMIYELFTRYDLINRFKIPVSCLITFAEALEVGYSKYK 215
Query: 747 NPFHNSLHAADVTQSTN-VLLNT 812
NP+HN +HAADVTQ+ + ++L+T
Sbjct: 216 NPYHNLIHAADVTQTVHYIMLHT 238
>BC022480-1|AAH22480.1| 545|Homo sapiens phosphodiesterase 1A,
calmodulin-dependent protein.
Length = 545
Score = 63.3 bits (147), Expect = 1e-09
Identities = 30/83 (36%), Positives = 48/83 (57%), Gaps = 2/83 (2%)
Frame = +3
Query: 570 DLDRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIR-D 746
D+D+W D+F + + S L + Y FT +L+ +IP + FA L Y +
Sbjct: 156 DVDKWSFDVFALNEASGEHSLKFMIYELFTRYDLINRFKIPVSCLITFAEALEVGYSKYK 215
Query: 747 NPFHNSLHAADVTQSTN-VLLNT 812
NP+HN +HAADVTQ+ + ++L+T
Sbjct: 216 NPYHNLIHAADVTQTVHYIMLHT 238
>AL110263-1|CAB53703.1| 519|Homo sapiens hypothetical protein
protein.
Length = 519
Score = 63.3 bits (147), Expect = 1e-09
Identities = 30/83 (36%), Positives = 48/83 (57%), Gaps = 2/83 (2%)
Frame = +3
Query: 570 DLDRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIR-D 746
D+D+W D+F + + S L + Y FT +L+ +IP + FA L Y +
Sbjct: 140 DVDKWSFDVFALNEASGEHSLKFMIYELFTRYDLINRFKIPVSCLITFAEALEVGYSKYK 199
Query: 747 NPFHNSLHAADVTQSTN-VLLNT 812
NP+HN +HAADVTQ+ + ++L+T
Sbjct: 200 NPYHNLIHAADVTQTVHYIMLHT 222
>AJ401610-1|CAC82208.1| 519|Homo sapiens 3'5' cyclic nucleotide
phosphodiesterase 1A5 protein.
Length = 519
Score = 63.3 bits (147), Expect = 1e-09
Identities = 30/83 (36%), Positives = 48/83 (57%), Gaps = 2/83 (2%)
Frame = +3
Query: 570 DLDRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIR-D 746
D+D+W D+F + + S L + Y FT +L+ +IP + FA L Y +
Sbjct: 140 DVDKWSFDVFALNEASGEHSLKFMIYELFTRYDLINRFKIPVSCLITFAEALEVGYSKYK 199
Query: 747 NPFHNSLHAADVTQSTN-VLLNT 812
NP+HN +HAADVTQ+ + ++L+T
Sbjct: 200 NPYHNLIHAADVTQTVHYIMLHT 222
>AB038224-9|BAB20054.1| 518|Homo sapiens calmodulin-dependent
phosphodiesterase protein.
Length = 518
Score = 63.3 bits (147), Expect = 1e-09
Identities = 30/83 (36%), Positives = 48/83 (57%), Gaps = 2/83 (2%)
Frame = +3
Query: 570 DLDRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIR-D 746
D+D+W D+F + + S L + Y FT +L+ +IP + FA L Y +
Sbjct: 122 DVDKWSFDVFALNEASGEHSLKFMIYELFTRYDLINRFKIPVSCLITFAEALEVGYSKYK 181
Query: 747 NPFHNSLHAADVTQSTN-VLLNT 812
NP+HN +HAADVTQ+ + ++L+T
Sbjct: 182 NPYHNLIHAADVTQTVHYIMLHT 204
>AB038224-8|BAB20053.1| 501|Homo sapiens calmodulin-dependent
phosphodiesterase protein.
Length = 501
Score = 63.3 bits (147), Expect = 1e-09
Identities = 30/83 (36%), Positives = 48/83 (57%), Gaps = 2/83 (2%)
Frame = +3
Query: 570 DLDRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIR-D 746
D+D+W D+F + + S L + Y FT +L+ +IP + FA L Y +
Sbjct: 122 DVDKWSFDVFALNEASGEHSLKFMIYELFTRYDLINRFKIPVSCLITFAEALEVGYSKYK 181
Query: 747 NPFHNSLHAADVTQSTN-VLLNT 812
NP+HN +HAADVTQ+ + ++L+T
Sbjct: 182 NPYHNLIHAADVTQTVHYIMLHT 204
>AB038224-7|BAB20057.1| 511|Homo sapiens calmodulin-dependent
phosphodiesterase protein.
Length = 511
Score = 63.3 bits (147), Expect = 1e-09
Identities = 30/83 (36%), Positives = 48/83 (57%), Gaps = 2/83 (2%)
Frame = +3
Query: 570 DLDRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIR-D 746
D+D+W D+F + + S L + Y FT +L+ +IP + FA L Y +
Sbjct: 122 DVDKWSFDVFALNEASGEHSLKFMIYELFTRYDLINRFKIPVSCLITFAEALEVGYSKYK 181
Query: 747 NPFHNSLHAADVTQSTN-VLLNT 812
NP+HN +HAADVTQ+ + ++L+T
Sbjct: 182 NPYHNLIHAADVTQTVHYIMLHT 204
>AB038224-6|BAB20052.1| 552|Homo sapiens calmodulin-dependent
phosphodiesterase protein.
Length = 552
Score = 63.3 bits (147), Expect = 1e-09
Identities = 30/83 (36%), Positives = 48/83 (57%), Gaps = 2/83 (2%)
Frame = +3
Query: 570 DLDRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIR-D 746
D+D+W D+F + + S L + Y FT +L+ +IP + FA L Y +
Sbjct: 156 DVDKWSFDVFALNEASGEHSLKFMIYELFTRYDLINRFKIPVSCLITFAEALEVGYSKYK 215
Query: 747 NPFHNSLHAADVTQSTN-VLLNT 812
NP+HN +HAADVTQ+ + ++L+T
Sbjct: 216 NPYHNLIHAADVTQTVHYIMLHT 238
>AB038224-5|BAB20050.1| 535|Homo sapiens calmodulin-dependent
phosphodiesterase protein.
Length = 535
Score = 63.3 bits (147), Expect = 1e-09
Identities = 30/83 (36%), Positives = 48/83 (57%), Gaps = 2/83 (2%)
Frame = +3
Query: 570 DLDRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIR-D 746
D+D+W D+F + + S L + Y FT +L+ +IP + FA L Y +
Sbjct: 156 DVDKWSFDVFALNEASGEHSLKFMIYELFTRYDLINRFKIPVSCLITFAEALEVGYSKYK 215
Query: 747 NPFHNSLHAADVTQSTN-VLLNT 812
NP+HN +HAADVTQ+ + ++L+T
Sbjct: 216 NPYHNLIHAADVTQTVHYIMLHT 238
>AB038224-4|BAB20056.1| 545|Homo sapiens calmodulin-dependent
phosphodiesterase protein.
Length = 545
Score = 63.3 bits (147), Expect = 1e-09
Identities = 30/83 (36%), Positives = 48/83 (57%), Gaps = 2/83 (2%)
Frame = +3
Query: 570 DLDRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIR-D 746
D+D+W D+F + + S L + Y FT +L+ +IP + FA L Y +
Sbjct: 156 DVDKWSFDVFALNEASGEHSLKFMIYELFTRYDLINRFKIPVSCLITFAEALEVGYSKYK 215
Query: 747 NPFHNSLHAADVTQSTN-VLLNT 812
NP+HN +HAADVTQ+ + ++L+T
Sbjct: 216 NPYHNLIHAADVTQTVHYIMLHT 238
>AB038224-3|BAB20051.1| 536|Homo sapiens calmodulin-dependent
phosphodiesterase protein.
Length = 536
Score = 63.3 bits (147), Expect = 1e-09
Identities = 30/83 (36%), Positives = 48/83 (57%), Gaps = 2/83 (2%)
Frame = +3
Query: 570 DLDRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIR-D 746
D+D+W D+F + + S L + Y FT +L+ +IP + FA L Y +
Sbjct: 140 DVDKWSFDVFALNEASGEHSLKFMIYELFTRYDLINRFKIPVSCLITFAEALEVGYSKYK 199
Query: 747 NPFHNSLHAADVTQSTN-VLLNT 812
NP+HN +HAADVTQ+ + ++L+T
Sbjct: 200 NPYHNLIHAADVTQTVHYIMLHT 222
>AB038224-2|BAB20049.1| 519|Homo sapiens calmodulin-dependent
phosphodiesterase protein.
Length = 519
Score = 63.3 bits (147), Expect = 1e-09
Identities = 30/83 (36%), Positives = 48/83 (57%), Gaps = 2/83 (2%)
Frame = +3
Query: 570 DLDRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIR-D 746
D+D+W D+F + + S L + Y FT +L+ +IP + FA L Y +
Sbjct: 140 DVDKWSFDVFALNEASGEHSLKFMIYELFTRYDLINRFKIPVSCLITFAEALEVGYSKYK 199
Query: 747 NPFHNSLHAADVTQSTN-VLLNT 812
NP+HN +HAADVTQ+ + ++L+T
Sbjct: 200 NPYHNLIHAADVTQTVHYIMLHT 222
>AB038224-1|BAB20055.1| 529|Homo sapiens calmodulin-dependent
phosphodiesterase protein.
Length = 529
Score = 63.3 bits (147), Expect = 1e-09
Identities = 30/83 (36%), Positives = 48/83 (57%), Gaps = 2/83 (2%)
Frame = +3
Query: 570 DLDRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIR-D 746
D+D+W D+F + + S L + Y FT +L+ +IP + FA L Y +
Sbjct: 140 DVDKWSFDVFALNEASGEHSLKFMIYELFTRYDLINRFKIPVSCLITFAEALEVGYSKYK 199
Query: 747 NPFHNSLHAADVTQSTN-VLLNT 812
NP+HN +HAADVTQ+ + ++L+T
Sbjct: 200 NPYHNLIHAADVTQTVHYIMLHT 222
>U40371-1|AAC50437.1| 634|Homo sapiens 3',5' cyclic nucleotide
phosphodiesterase protein.
Length = 634
Score = 62.1 bits (144), Expect = 2e-09
Identities = 38/134 (28%), Positives = 61/134 (45%), Gaps = 1/134 (0%)
Frame = +3
Query: 408 KKKEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWG 587
+ EKPR + V+R T++ G P +E D+D+W
Sbjct: 120 RSDEKPRFKSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIEA---------LKDVDKWS 170
Query: 588 VDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIR-DNPFHNS 764
D+F + + S L + Y T +L++ +IP ++F L Y + NP+HN
Sbjct: 171 FDVFSLNEASGDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNL 230
Query: 765 LHAADVTQSTNVLL 806
+HAADVTQ+ + LL
Sbjct: 231 MHAADVTQTVHYLL 244
>BC022525-1|AAH22525.1| 634|Homo sapiens PDE1C protein protein.
Length = 634
Score = 62.1 bits (144), Expect = 2e-09
Identities = 38/134 (28%), Positives = 61/134 (45%), Gaps = 1/134 (0%)
Frame = +3
Query: 408 KKKEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWG 587
+ EKPR + V+R T++ G P +E D+D+W
Sbjct: 120 RSDEKPRFKSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIEA---------LKDVDKWS 170
Query: 588 VDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIR-DNPFHNS 764
D+F + + S L + Y T +L++ +IP ++F L Y + NP+HN
Sbjct: 171 FDVFSLNEASGDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNL 230
Query: 765 LHAADVTQSTNVLL 806
+HAADVTQ+ + LL
Sbjct: 231 MHAADVTQTVHYLL 244
>BC022479-1|AAH22479.1| 634|Homo sapiens PDE1C protein protein.
Length = 634
Score = 62.1 bits (144), Expect = 2e-09
Identities = 38/134 (28%), Positives = 61/134 (45%), Gaps = 1/134 (0%)
Frame = +3
Query: 408 KKKEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWG 587
+ EKPR + V+R T++ G P +E D+D+W
Sbjct: 120 RSDEKPRFKSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIEA---------LKDVDKWS 170
Query: 588 VDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIR-DNPFHNS 764
D+F + + S L + Y T +L++ +IP ++F L Y + NP+HN
Sbjct: 171 FDVFSLNEASGDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNL 230
Query: 765 LHAADVTQSTNVLL 806
+HAADVTQ+ + LL
Sbjct: 231 MHAADVTQTVHYLL 244
>AC006377-1|AAS07516.1| 591|Homo sapiens unknown protein.
Length = 591
Score = 62.1 bits (144), Expect = 2e-09
Identities = 38/134 (28%), Positives = 61/134 (45%), Gaps = 1/134 (0%)
Frame = +3
Query: 408 KKKEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHXXXXXXXXSDLDRWG 587
+ EKPR + V+R T++ G P +E D+D+W
Sbjct: 77 RSDEKPRFKSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIEA---------LKDVDKWS 127
Query: 588 VDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIR-DNPFHNS 764
D+F + + S L + Y T +L++ +IP ++F L Y + NP+HN
Sbjct: 128 FDVFSLNEASGDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNL 187
Query: 765 LHAADVTQSTNVLL 806
+HAADVTQ+ + LL
Sbjct: 188 MHAADVTQTVHYLL 201
>U40372-1|AAA96961.1| 564|Homo sapiens PDE1C3 protein.
Length = 564
Score = 61.7 bits (143), Expect = 3e-09
Identities = 28/80 (35%), Positives = 45/80 (56%), Gaps = 1/80 (1%)
Frame = +3
Query: 570 DLDRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIR-D 746
D+D+W D+F + + S L + Y T +L++ +IP ++F L Y +
Sbjct: 20 DVDKWSFDVFSLNEASGDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHK 79
Query: 747 NPFHNSLHAADVTQSTNVLL 806
NP+HN +HAADVTQ+ + LL
Sbjct: 80 NPYHNLMHAADVTQTVHYLL 99
>EF108327-1|ABL14249.1| 502|Homo sapiens phosphodiesterase PDE7B2
protein.
Length = 502
Score = 61.7 bits (143), Expect = 3e-09
Identities = 32/92 (34%), Positives = 46/92 (50%)
Frame = +3
Query: 567 SDLDRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRD 746
S + W DIF L+ G L + F + L+ ++ T F V + E Y
Sbjct: 162 SKVGMWDFDIFLFDRLTNGNSLVTLLCHLFNTHGLIHHFKLDMVTLHRFLVMVQEDYHSQ 221
Query: 747 NPFHNSLHAADVTQSTNVLLNTPALNAVFTPL 842
NP+HN++HAADVTQ+ + L P L + TPL
Sbjct: 222 NPYHNAVHAADVTQAMHCYLKEPKLASFLTPL 253
>BC075083-1|AAH75083.1| 450|Homo sapiens phosphodiesterase 7B
protein.
Length = 450
Score = 61.7 bits (143), Expect = 3e-09
Identities = 32/92 (34%), Positives = 46/92 (50%)
Frame = +3
Query: 567 SDLDRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRD 746
S + W DIF L+ G L + F + L+ ++ T F V + E Y
Sbjct: 110 SKVGMWDFDIFLFDRLTNGNSLVTLLCHLFNTHGLIHHFKLDMVTLHRFLVMVQEDYHSQ 169
Query: 747 NPFHNSLHAADVTQSTNVLLNTPALNAVFTPL 842
NP+HN++HAADVTQ+ + L P L + TPL
Sbjct: 170 NPYHNAVHAADVTQAMHCYLKEPKLASFLTPL 201
>BC075082-1|AAH75082.1| 450|Homo sapiens phosphodiesterase 7B
protein.
Length = 450
Score = 61.7 bits (143), Expect = 3e-09
Identities = 32/92 (34%), Positives = 46/92 (50%)
Frame = +3
Query: 567 SDLDRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRD 746
S + W DIF L+ G L + F + L+ ++ T F V + E Y
Sbjct: 110 SKVGMWDFDIFLFDRLTNGNSLVTLLCHLFNTHGLIHHFKLDMVTLHRFLVMVQEDYHSQ 169
Query: 747 NPFHNSLHAADVTQSTNVLLNTPALNAVFTPL 842
NP+HN++HAADVTQ+ + L P L + TPL
Sbjct: 170 NPYHNAVHAADVTQAMHCYLKEPKLASFLTPL 201
>AL360178-1|CAH73075.1| 450|Homo sapiens phosphodiesterase 7B
protein.
Length = 450
Score = 61.7 bits (143), Expect = 3e-09
Identities = 32/92 (34%), Positives = 46/92 (50%)
Frame = +3
Query: 567 SDLDRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRD 746
S + W DIF L+ G L + F + L+ ++ T F V + E Y
Sbjct: 110 SKVGMWDFDIFLFDRLTNGNSLVTLLCHLFNTHGLIHHFKLDMVTLHRFLVMVQEDYHSQ 169
Query: 747 NPFHNSLHAADVTQSTNVLLNTPALNAVFTPL 842
NP+HN++HAADVTQ+ + L P L + TPL
Sbjct: 170 NPYHNAVHAADVTQAMHCYLKEPKLASFLTPL 201
>AL138828-4|CAI95287.1| 450|Homo sapiens phosphodiesterase 7B
protein.
Length = 450
Score = 61.7 bits (143), Expect = 3e-09
Identities = 32/92 (34%), Positives = 46/92 (50%)
Frame = +3
Query: 567 SDLDRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRD 746
S + W DIF L+ G L + F + L+ ++ T F V + E Y
Sbjct: 110 SKVGMWDFDIFLFDRLTNGNSLVTLLCHLFNTHGLIHHFKLDMVTLHRFLVMVQEDYHSQ 169
Query: 747 NPFHNSLHAADVTQSTNVLLNTPALNAVFTPL 842
NP+HN++HAADVTQ+ + L P L + TPL
Sbjct: 170 NPYHNAVHAADVTQAMHCYLKEPKLASFLTPL 201
>AL138828-3|CAI95286.1| 199|Homo sapiens phosphodiesterase 7B
protein.
Length = 199
Score = 61.7 bits (143), Expect = 3e-09
Identities = 32/92 (34%), Positives = 46/92 (50%)
Frame = +3
Query: 567 SDLDRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRD 746
S + W DIF L+ G L + F + L+ ++ T F V + E Y
Sbjct: 4 SKVGMWDFDIFLFDRLTNGNSLVTLLCHLFNTHGLIHHFKLDMVTLHRFLVMVQEDYHSQ 63
Query: 747 NPFHNSLHAADVTQSTNVLLNTPALNAVFTPL 842
NP+HN++HAADVTQ+ + L P L + TPL
Sbjct: 64 NPYHNAVHAADVTQAMHCYLKEPKLASFLTPL 95
>AL133319-1|CAH73332.1| 450|Homo sapiens phosphodiesterase 7B
protein.
Length = 450
Score = 61.7 bits (143), Expect = 3e-09
Identities = 32/92 (34%), Positives = 46/92 (50%)
Frame = +3
Query: 567 SDLDRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRD 746
S + W DIF L+ G L + F + L+ ++ T F V + E Y
Sbjct: 110 SKVGMWDFDIFLFDRLTNGNSLVTLLCHLFNTHGLIHHFKLDMVTLHRFLVMVQEDYHSQ 169
Query: 747 NPFHNSLHAADVTQSTNVLLNTPALNAVFTPL 842
NP+HN++HAADVTQ+ + L P L + TPL
Sbjct: 170 NPYHNAVHAADVTQAMHCYLKEPKLASFLTPL 201
>AK091734-1|BAC03734.1| 769|Homo sapiens (EC 3.1.4.17). protein.
Length = 769
Score = 61.7 bits (143), Expect = 3e-09
Identities = 28/80 (35%), Positives = 45/80 (56%), Gaps = 1/80 (1%)
Frame = +3
Query: 570 DLDRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIR-D 746
D+D+W D+F + + S L + Y T +L++ +IP ++F L Y +
Sbjct: 225 DVDKWSFDVFSLNEASGDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHK 284
Query: 747 NPFHNSLHAADVTQSTNVLL 806
NP+HN +HAADVTQ+ + LL
Sbjct: 285 NPYHNLMHAADVTQTVHYLL 304
>AJ251860-1|CAB92441.1| 450|Homo sapiens phosphodiesterase 7B
protein.
Length = 450
Score = 61.7 bits (143), Expect = 3e-09
Identities = 32/92 (34%), Positives = 46/92 (50%)
Frame = +3
Query: 567 SDLDRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRD 746
S + W DIF L+ G L + F + L+ ++ T F V + E Y
Sbjct: 110 SKVGMWDFDIFLFDRLTNGNSLVTLLCHLFNTHGLIHHFKLDMVTLHRFLVMVQEDYHSQ 169
Query: 747 NPFHNSLHAADVTQSTNVLLNTPALNAVFTPL 842
NP+HN++HAADVTQ+ + L P L + TPL
Sbjct: 170 NPYHNAVHAADVTQAMHCYLKEPKLASFLTPL 201
>AB209990-1|BAE06072.1| 586|Homo sapiens PDE7B variant protein
protein.
Length = 586
Score = 61.7 bits (143), Expect = 3e-09
Identities = 32/92 (34%), Positives = 46/92 (50%)
Frame = +3
Query: 567 SDLDRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRD 746
S + W DIF L+ G L + F + L+ ++ T F V + E Y
Sbjct: 246 SKVGMWDFDIFLFDRLTNGNSLVTLLCHLFNTHGLIHHFKLDMVTLHRFLVMVQEDYHSQ 305
Query: 747 NPFHNSLHAADVTQSTNVLLNTPALNAVFTPL 842
NP+HN++HAADVTQ+ + L P L + TPL
Sbjct: 306 NPYHNAVHAADVTQAMHCYLKEPKLASFLTPL 337
>AB038040-1|BAA96537.1| 450|Homo sapiens cyclic nucleotide
phosphodiesterase 7B protein.
Length = 450
Score = 61.7 bits (143), Expect = 3e-09
Identities = 32/92 (34%), Positives = 46/92 (50%)
Frame = +3
Query: 567 SDLDRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRD 746
S + W DIF L+ G L + F + L+ ++ T F V + E Y
Sbjct: 110 SKVGMWDFDIFLFDRLTNGNSLVTLLCHLFNTHGLIHHFKLDMVTLHRFLVMVQEDYHSQ 169
Query: 747 NPFHNSLHAADVTQSTNVLLNTPALNAVFTPL 842
NP+HN++HAADVTQ+ + L P L + TPL
Sbjct: 170 NPYHNAVHAADVTQAMHCYLKEPKLASFLTPL 201
>U67932-1|AAB65772.1| 456|Homo sapiens cAMP phosphodiesterase PDE7
protein.
Length = 456
Score = 58.8 bits (136), Expect = 2e-08
Identities = 29/86 (33%), Positives = 42/86 (48%)
Frame = +3
Query: 582 WGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHN 761
W DIF L+ G L ++ + F+ L+ + F V + E Y NP+HN
Sbjct: 128 WNFDIFLFDRLTNGNSLVSLTFHLFSLHGLIEYFHLDMMKLRRFLVMIQEDYHSQNPYHN 187
Query: 762 SLHAADVTQSTNVLLNTPALNAVFTP 839
++HAADVTQ+ + L P L TP
Sbjct: 188 AVHAADVTQAMHCYLKEPKLANSVTP 213
>L12052-1|AAA35644.2| 482|Homo sapiens cAMP phosphodiesterase PDE7
protein.
Length = 482
Score = 58.8 bits (136), Expect = 2e-08
Identities = 29/86 (33%), Positives = 42/86 (48%)
Frame = +3
Query: 582 WGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHN 761
W DIF L+ G L ++ + F+ L+ + F V + E Y NP+HN
Sbjct: 154 WNFDIFLFDRLTNGNSLVSLTFHLFSLHGLIEYFHLDMMKLRRFLVMIQEDYHSQNPYHN 213
Query: 762 SLHAADVTQSTNVLLNTPALNAVFTP 839
++HAADVTQ+ + L P L TP
Sbjct: 214 AVHAADVTQAMHCYLKEPKLANSVTP 239
>BC126360-1|AAI26361.1| 456|Homo sapiens phosphodiesterase 7A
protein.
Length = 456
Score = 58.8 bits (136), Expect = 2e-08
Identities = 29/86 (33%), Positives = 42/86 (48%)
Frame = +3
Query: 582 WGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHN 761
W DIF L+ G L ++ + F+ L+ + F V + E Y NP+HN
Sbjct: 128 WNFDIFLFDRLTNGNSLVSLTFHLFSLHGLIEYFHLDMMKLRRFLVMIQEDYHSQNPYHN 187
Query: 762 SLHAADVTQSTNVLLNTPALNAVFTP 839
++HAADVTQ+ + L P L TP
Sbjct: 188 AVHAADVTQAMHCYLKEPKLANSVTP 213
>AF332652-1|AAK57640.1| 424|Homo sapiens cAMP-specific cyclic
nucleotide phosphodiesterase PDE7A3 protein.
Length = 424
Score = 58.8 bits (136), Expect = 2e-08
Identities = 29/86 (33%), Positives = 42/86 (48%)
Frame = +3
Query: 582 WGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHN 761
W DIF L+ G L ++ + F+ L+ + F V + E Y NP+HN
Sbjct: 154 WNFDIFLFDRLTNGNSLVSLTFHLFSLHGLIEYFHLDMMKLRRFLVMIQEDYHSQNPYHN 213
Query: 762 SLHAADVTQSTNVLLNTPALNAVFTP 839
++HAADVTQ+ + L P L TP
Sbjct: 214 AVHAADVTQAMHCYLKEPKLANSVTP 239
>U86078-1|AAC51872.1| 536|Homo sapiens calmodulin-stimulated
phosphodiesterase PDE1B1 protein.
Length = 536
Score = 54.4 bits (125), Expect = 5e-07
Identities = 37/148 (25%), Positives = 63/148 (42%), Gaps = 1/148 (0%)
Frame = +3
Query: 366 LPSLQVEETSERGAKKKEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHX 545
L S ++ +G + +EKP+ + V+R T + G P Y +
Sbjct: 101 LASTFTQQARAKGRRAEEKPKFRSIVHAVQAGIFVERMFRRTYTSVG---PTYSTAVLNC 157
Query: 546 XXXXXXXSDLDRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTL 725
+LD W D+F + + L + + T L++ +IP ++F L
Sbjct: 158 L------KNLDLWCFDVFSLNQAADDHALRTIVFELLTRHNLISRFKIPTVFLMSFLDAL 211
Query: 726 XEHYIR-DNPFHNSLHAADVTQSTNVLL 806
Y + NP+HN +HAADVTQ+ + L
Sbjct: 212 ETGYGKYKNPYHNQIHAADVTQTVHCFL 239
>U56976-1|AAC50769.1| 536|Homo sapiens calmodulin dependent
phosphodiesterase PDE1B1 protein.
Length = 536
Score = 54.4 bits (125), Expect = 5e-07
Identities = 37/148 (25%), Positives = 63/148 (42%), Gaps = 1/148 (0%)
Frame = +3
Query: 366 LPSLQVEETSERGAKKKEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHX 545
L S ++ +G + +EKP+ + V+R T + G P Y +
Sbjct: 101 LASTFTQQARAKGRRAEEKPKFRSIVHAVQAGIFVERMFRRTYTSVG---PTYSTAVLNC 157
Query: 546 XXXXXXXSDLDRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTL 725
+LD W D+F + + L + + T L++ +IP ++F L
Sbjct: 158 L------KNLDLWCFDVFSLNQAADDHALRTIVFELLTRHNLISRFKIPTVFLMSFLDAL 211
Query: 726 XEHYIR-DNPFHNSLHAADVTQSTNVLL 806
Y + NP+HN +HAADVTQ+ + L
Sbjct: 212 ETGYGKYKNPYHNQIHAADVTQTVHCFL 239
>BC032226-1|AAH32226.1| 536|Homo sapiens phosphodiesterase 1B,
calmodulin-dependent protein.
Length = 536
Score = 54.4 bits (125), Expect = 5e-07
Identities = 37/148 (25%), Positives = 63/148 (42%), Gaps = 1/148 (0%)
Frame = +3
Query: 366 LPSLQVEETSERGAKKKEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHX 545
L S ++ +G + +EKP+ + V+R T + G P Y +
Sbjct: 101 LASTFTQQARAKGRRAEEKPKFRSIVHAVQAGIFVERMFRRTYTSVG---PTYSTAVLNC 157
Query: 546 XXXXXXXSDLDRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTL 725
+LD W D+F + + L + + T L++ +IP ++F L
Sbjct: 158 L------KNLDLWCFDVFSLNQAADDHALRTIVFELLTRHNLISRFKIPTVFLMSFLDAL 211
Query: 726 XEHYIR-DNPFHNSLHAADVTQSTNVLL 806
Y + NP+HN +HAADVTQ+ + L
Sbjct: 212 ETGYGKYKNPYHNQIHAADVTQTVHCFL 239
>AJ401609-1|CAC82207.1| 516|Homo sapiens 3'5' cyclic nucleotide
phosphodiesterase 1B2 protein.
Length = 516
Score = 54.4 bits (125), Expect = 5e-07
Identities = 37/148 (25%), Positives = 63/148 (42%), Gaps = 1/148 (0%)
Frame = +3
Query: 366 LPSLQVEETSERGAKKKEKPRHGGPATTMSQISGVKRTLTHTNSFTGERVPRYGVETPHX 545
L S ++ +G + +EKP+ + V+R T + G P Y +
Sbjct: 81 LASTFTQQARAKGRRAEEKPKFRSIVHAVQAGIFVERMFRRTYTSVG---PTYSTAVLNC 137
Query: 546 XXXXXXXSDLDRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTL 725
+LD W D+F + + L + + T L++ +IP ++F L
Sbjct: 138 L------KNLDLWCFDVFSLNQAADDHALRTIVFELLTRHNLISRFKIPTVFLMSFLDAL 191
Query: 726 XEHYIR-DNPFHNSLHAADVTQSTNVLL 806
Y + NP+HN +HAADVTQ+ + L
Sbjct: 192 ETGYGKYKNPYHNQIHAADVTQTVHCFL 219
>BX538092-1|CAD98011.1| 399|Homo sapiens hypothetical protein
protein.
Length = 399
Score = 53.2 bits (122), Expect = 1e-06
Identities = 25/80 (31%), Positives = 41/80 (51%), Gaps = 1/80 (1%)
Frame = +3
Query: 570 DLDRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIR-D 746
+LD W D+F + + L + + T L++ +IP ++F L Y +
Sbjct: 23 NLDLWCFDVFSLNQAADDHALRTIVFELLTRHNLISRFKIPTVFLMSFLDALETGYGKYK 82
Query: 747 NPFHNSLHAADVTQSTNVLL 806
NP+HN +HAADVTQ+ + L
Sbjct: 83 NPYHNQIHAADVTQTVHCFL 102
>U36798-1|AAB18673.1| 1141|Homo sapiens platelet cGI-PDE protein.
Length = 1141
Score = 49.6 bits (113), Expect = 1e-05
Identities = 29/84 (34%), Positives = 40/84 (47%), Gaps = 3/84 (3%)
Frame = +3
Query: 573 LDRWGVDIFRIGD---LSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIR 743
L+ W IF + + CGR L+ V+Y F L +IP R F+ + L Y R
Sbjct: 689 LNTWNFPIFDLVENIGRKCGRILSQVSYRLFEDMGLFEAFKIPIREFMNYFHALEIGY-R 747
Query: 744 DNPFHNSLHAADVTQSTNVLLNTP 815
D P+HN +HA DV + L P
Sbjct: 748 DIPYHNRIHATDVLHAVWYLTTQP 771
>M91667-1|AAA35912.2| 1141|Homo sapiens cGMP-inhibited cAMP
phosphodiesterase protein.
Length = 1141
Score = 49.6 bits (113), Expect = 1e-05
Identities = 29/84 (34%), Positives = 40/84 (47%), Gaps = 3/84 (3%)
Frame = +3
Query: 573 LDRWGVDIFRIGD---LSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIR 743
L+ W IF + + CGR L+ V+Y F L +IP R F+ + L Y R
Sbjct: 689 LNTWNFPIFDLVENIGRKCGRILSQVSYRLFEDMGLFEAFKIPIREFMNYFHALEIGY-R 747
Query: 744 DNPFHNSLHAADVTQSTNVLLNTP 815
D P+HN +HA DV + L P
Sbjct: 748 DIPYHNRIHATDVLHAVWYLTTQP 771
>BC117371-1|AAI17372.1| 1141|Homo sapiens phosphodiesterase 3A,
cGMP-inhibited protein.
Length = 1141
Score = 49.6 bits (113), Expect = 1e-05
Identities = 29/84 (34%), Positives = 40/84 (47%), Gaps = 3/84 (3%)
Frame = +3
Query: 573 LDRWGVDIFRIGD---LSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIR 743
L+ W IF + + CGR L+ V+Y F L +IP R F+ + L Y R
Sbjct: 689 LNTWNFPIFDLVENIGRKCGRILSQVSYRLFEDMGLFEAFKIPIREFMNYFHALEIGY-R 747
Query: 744 DNPFHNSLHAADVTQSTNVLLNTP 815
D P+HN +HA DV + L P
Sbjct: 748 DIPYHNRIHATDVLHAVWYLTTQP 771
>BC117369-1|AAI17370.1| 1141|Homo sapiens phosphodiesterase 3A,
cGMP-inhibited protein.
Length = 1141
Score = 49.6 bits (113), Expect = 1e-05
Identities = 29/84 (34%), Positives = 40/84 (47%), Gaps = 3/84 (3%)
Frame = +3
Query: 573 LDRWGVDIFRIGD---LSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIR 743
L+ W IF + + CGR L+ V+Y F L +IP R F+ + L Y R
Sbjct: 689 LNTWNFPIFDLVENIGRKCGRILSQVSYRLFEDMGLFEAFKIPIREFMNYFHALEIGY-R 747
Query: 744 DNPFHNSLHAADVTQSTNVLLNTP 815
D P+HN +HA DV + L P
Sbjct: 748 DIPYHNRIHATDVLHAVWYLTTQP 771
>AJ005036-1|CAA06304.1| 1141|Homo sapiens phosphodiesterase 3A
protein.
Length = 1141
Score = 49.6 bits (113), Expect = 1e-05
Identities = 29/84 (34%), Positives = 40/84 (47%), Gaps = 3/84 (3%)
Frame = +3
Query: 573 LDRWGVDIFRIGD---LSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIR 743
L+ W IF + + CGR L+ V+Y F L +IP R F+ + L Y R
Sbjct: 689 LNTWNFPIFDLVENIGRKCGRILSQVSYRLFEDMGLFEAFKIPIREFMNYFHALEIGY-R 747
Query: 744 DNPFHNSLHAADVTQSTNVLLNTP 815
D P+HN +HA DV + L P
Sbjct: 748 DIPYHNRIHATDVLHAVWYLTTQP 771
>X95520-1|CAA64774.1| 1112|Homo sapiens cyclic nucleotide
phosphodiesterase protein.
Length = 1112
Score = 49.2 bits (112), Expect = 2e-05
Identities = 30/85 (35%), Positives = 42/85 (49%), Gaps = 4/85 (4%)
Frame = +3
Query: 573 LDRWGVDIF----RIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYI 740
+ W IF ++G+ S GR L+ V YT F LL +IP + F+ + L Y
Sbjct: 674 MSNWNFPIFELVEKMGEKS-GRILSQVMYTLFQDTGLLEIFKIPTQQFMNYFRALENGY- 731
Query: 741 RDNPFHNSLHAADVTQSTNVLLNTP 815
RD P+HN +HA DV + L P
Sbjct: 732 RDIPYHNRIHATDVLHAVWYLTTRP 756
>U38178-1|AAC50724.1| 1112|Homo sapiens cyclic nucleotide
phophodiesterase protein.
Length = 1112
Score = 49.2 bits (112), Expect = 2e-05
Identities = 30/85 (35%), Positives = 42/85 (49%), Gaps = 4/85 (4%)
Frame = +3
Query: 573 LDRWGVDIF----RIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYI 740
+ W IF ++G+ S GR L+ V YT F LL +IP + F+ + L Y
Sbjct: 674 MSNWNFPIFELVEKMGEKS-GRILSQVMYTLFQDTGLLEIFKIPTQQFMNYFRALENGY- 731
Query: 741 RDNPFHNSLHAADVTQSTNVLLNTP 815
RD P+HN +HA DV + L P
Sbjct: 732 RDIPYHNRIHATDVLHAVWYLTTRP 756
>D50640-1|BAA09306.1| 1112|Homo sapiens phosphodiesterase 3B
protein.
Length = 1112
Score = 49.2 bits (112), Expect = 2e-05
Identities = 30/85 (35%), Positives = 42/85 (49%), Gaps = 4/85 (4%)
Frame = +3
Query: 573 LDRWGVDIF----RIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYI 740
+ W IF ++G+ S GR L+ V YT F LL +IP + F+ + L Y
Sbjct: 674 MSNWNFPIFELVEKMGEKS-GRILSQVMYTLFQDTGLLEIFKIPTQQFMNYFRALENGY- 731
Query: 741 RDNPFHNSLHAADVTQSTNVLLNTP 815
RD P+HN +HA DV + L P
Sbjct: 732 RDIPYHNRIHATDVLHAVWYLTTRP 756
>BC150307-1|AAI50308.1| 1112|Homo sapiens phosphodiesterase 3B,
cGMP-inhibited protein.
Length = 1112
Score = 49.2 bits (112), Expect = 2e-05
Identities = 30/85 (35%), Positives = 42/85 (49%), Gaps = 4/85 (4%)
Frame = +3
Query: 573 LDRWGVDIF----RIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYI 740
+ W IF ++G+ S GR L+ V YT F LL +IP + F+ + L Y
Sbjct: 674 MSNWNFPIFELVEKMGEKS-GRILSQVMYTLFQDTGLLEIFKIPTQQFMNYFRALENGY- 731
Query: 741 RDNPFHNSLHAADVTQSTNVLLNTP 815
RD P+HN +HA DV + L P
Sbjct: 732 RDIPYHNRIHATDVLHAVWYLTTRP 756
>AY459346-1|AAR24292.1| 1112|Homo sapiens cGMP-inhibited cAMP
phophodiesterase protein.
Length = 1112
Score = 49.2 bits (112), Expect = 2e-05
Identities = 30/85 (35%), Positives = 42/85 (49%), Gaps = 4/85 (4%)
Frame = +3
Query: 573 LDRWGVDIF----RIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYI 740
+ W IF ++G+ S GR L+ V YT F LL +IP + F+ + L Y
Sbjct: 674 MSNWNFPIFELVEKMGEKS-GRILSQVMYTLFQDTGLLEIFKIPTQQFMNYFRALENGY- 731
Query: 741 RDNPFHNSLHAADVTQSTNVLLNTP 815
RD P+HN +HA DV + L P
Sbjct: 732 RDIPYHNRIHATDVLHAVWYLTTRP 756
>BC075822-1|AAH75822.1| 829|Homo sapiens phosphodiesterase 8A
protein.
Length = 829
Score = 45.6 bits (103), Expect = 2e-04
Identities = 23/87 (26%), Positives = 37/87 (42%)
Frame = +3
Query: 582 WGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHN 761
W DIF + + RPL + F + L T ++ + +Y NP+HN
Sbjct: 498 WDFDIFELEAATHNRPLIYLGLKMFARFGICEFLHCSESTLRSWLQIIEANYHSSNPYHN 557
Query: 762 SLHAADVTQSTNVLLNTPALNAVFTPL 842
S H+ADV +T L+ + P+
Sbjct: 558 STHSADVLHATAYFLSKERIKETLDPI 584
>BC060762-1|AAH60762.1| 829|Homo sapiens phosphodiesterase 8A
protein.
Length = 829
Score = 45.6 bits (103), Expect = 2e-04
Identities = 23/87 (26%), Positives = 37/87 (42%)
Frame = +3
Query: 582 WGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHN 761
W DIF + + RPL + F + L T ++ + +Y NP+HN
Sbjct: 498 WDFDIFELEAATHNRPLIYLGLKMFARFGICEFLHCSESTLRSWLQIIEANYHSSNPYHN 557
Query: 762 SLHAADVTQSTNVLLNTPALNAVFTPL 842
S H+ADV +T L+ + P+
Sbjct: 558 STHSADVLHATAYFLSKERIKETLDPI 584
>AF388187-1|AAL18614.1| 582|Homo sapiens cAMP phosphodiesterase
PDE8A5 protein.
Length = 582
Score = 45.6 bits (103), Expect = 2e-04
Identities = 23/87 (26%), Positives = 37/87 (42%)
Frame = +3
Query: 582 WGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHN 761
W DIF + + RPL + F + L T ++ + +Y NP+HN
Sbjct: 251 WDFDIFELEAATHNRPLIYLGLKMFARFGICEFLHCSESTLRSWLQIIEANYHSSNPYHN 310
Query: 762 SLHAADVTQSTNVLLNTPALNAVFTPL 842
S H+ADV +T L+ + P+
Sbjct: 311 STHSADVLHATAYFLSKERIKETLDPI 337
>AF388186-1|AAL18613.1| 582|Homo sapiens cAMP phosphodiesterase
PDE8A4 protein.
Length = 582
Score = 45.6 bits (103), Expect = 2e-04
Identities = 23/87 (26%), Positives = 37/87 (42%)
Frame = +3
Query: 582 WGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHN 761
W DIF + + RPL + F + L T ++ + +Y NP+HN
Sbjct: 251 WDFDIFELEAATHNRPLIYLGLKMFARFGICEFLHCSESTLRSWLQIIEANYHSSNPYHN 310
Query: 762 SLHAADVTQSTNVLLNTPALNAVFTPL 842
S H+ADV +T L+ + P+
Sbjct: 311 STHSADVLHATAYFLSKERIKETLDPI 337
>AF388185-1|AAL18612.1| 449|Homo sapiens cAMP phosphodiesterase
PDE8A3 protein.
Length = 449
Score = 45.6 bits (103), Expect = 2e-04
Identities = 23/87 (26%), Positives = 37/87 (42%)
Frame = +3
Query: 582 WGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHN 761
W DIF + + RPL + F + L T ++ + +Y NP+HN
Sbjct: 118 WDFDIFELEAATHNRPLIYLGLKMFARFGICEFLHCSESTLRSWLQIIEANYHSSNPYHN 177
Query: 762 SLHAADVTQSTNVLLNTPALNAVFTPL 842
S H+ADV +T L+ + P+
Sbjct: 178 STHSADVLHATAYFLSKERIKETLDPI 204
>AF388184-1|AAL18611.1| 783|Homo sapiens cAMP phosphodiesterase
PDE8A2 protein.
Length = 783
Score = 45.6 bits (103), Expect = 2e-04
Identities = 23/87 (26%), Positives = 37/87 (42%)
Frame = +3
Query: 582 WGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHN 761
W DIF + + RPL + F + L T ++ + +Y NP+HN
Sbjct: 452 WDFDIFELEAATHNRPLIYLGLKMFARFGICEFLHCSESTLRSWLQIIEANYHSSNPYHN 511
Query: 762 SLHAADVTQSTNVLLNTPALNAVFTPL 842
S H+ADV +T L+ + P+
Sbjct: 512 STHSADVLHATAYFLSKERIKETLDPI 538
>AF388183-1|AAL18610.1| 829|Homo sapiens cAMP phosphodiesterase
PDE8A1 protein.
Length = 829
Score = 45.6 bits (103), Expect = 2e-04
Identities = 23/87 (26%), Positives = 37/87 (42%)
Frame = +3
Query: 582 WGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHN 761
W DIF + + RPL + F + L T ++ + +Y NP+HN
Sbjct: 498 WDFDIFELEAATHNRPLIYLGLKMFARFGICEFLHCSESTLRSWLQIIEANYHSSNPYHN 557
Query: 762 SLHAADVTQSTNVLLNTPALNAVFTPL 842
S H+ADV +T L+ + P+
Sbjct: 558 STHSADVLHATAYFLSKERIKETLDPI 584
>AF332653-1|AAK57641.1| 829|Homo sapiens cAMP-specific cyclic
nucleotide phosphodiesterase PDE8A1 protein.
Length = 829
Score = 45.6 bits (103), Expect = 2e-04
Identities = 23/87 (26%), Positives = 37/87 (42%)
Frame = +3
Query: 582 WGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHN 761
W DIF + + RPL + F + L T ++ + +Y NP+HN
Sbjct: 498 WDFDIFELEAATHNRPLIYLGLKMFARFGICEFLHCSESTLRSWLQIIEANYHSSNPYHN 557
Query: 762 SLHAADVTQSTNVLLNTPALNAVFTPL 842
S H+ADV +T L+ + P+
Sbjct: 558 STHSADVLHATAYFLSKERIKETLDPI 584
>AF056490-1|AAC39763.1| 713|Homo sapiens cAMP-specific
phosphodiesterase 8A protein.
Length = 713
Score = 45.6 bits (103), Expect = 2e-04
Identities = 23/87 (26%), Positives = 37/87 (42%)
Frame = +3
Query: 582 WGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPFHN 761
W DIF + + RPL + F + L T ++ + +Y NP+HN
Sbjct: 382 WDFDIFELEAATHNRPLIYLGLKMFARFGICEFLHCSESTLRSWLQIIEANYHSSNPYHN 441
Query: 762 SLHAADVTQSTNVLLNTPALNAVFTPL 842
S H+ADV +T L+ + P+
Sbjct: 442 STHSADVLHATAYFLSKERIKETLDPI 468
>BC035144-1|AAH35144.1| 385|Homo sapiens PDE8B protein protein.
Length = 385
Score = 41.5 bits (93), Expect = 0.004
Identities = 22/77 (28%), Positives = 35/77 (45%)
Frame = +3
Query: 576 DRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPF 755
+ W +IF + ++ RPL + F+ + L T A+ + +Y N +
Sbjct: 55 ESWDFNIFELEAITHKRPLVYLGLKVFSRFGVCEFLNCSETTLRAWFQVIEANYHSSNAY 114
Query: 756 HNSLHAADVTQSTNVLL 806
HNS HAADV +T L
Sbjct: 115 HNSTHAADVLHATAFFL 131
>AY423729-1|AAS00492.1| 350|Homo sapiens proliferation-inducing
gene 22 protein protein.
Length = 350
Score = 41.5 bits (93), Expect = 0.004
Identities = 22/77 (28%), Positives = 35/77 (45%)
Frame = +3
Query: 576 DRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPF 755
+ W +IF + ++ RPL + F+ + L T A+ + +Y N +
Sbjct: 20 ESWDFNIFELEAITHKRPLVYLGLKVFSRFGVCEFLNCSETTLRAWFQVIEANYHSSNAY 79
Query: 756 HNSLHAADVTQSTNVLL 806
HNS HAADV +T L
Sbjct: 80 HNSTHAADVLHATAFFL 96
>AY129950-3|AAN71727.1| 788|Homo sapiens cAMP-specific
phosphodiesterase 8B3 protein.
Length = 788
Score = 41.5 bits (93), Expect = 0.004
Identities = 22/77 (28%), Positives = 35/77 (45%)
Frame = +3
Query: 576 DRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPF 755
+ W +IF + ++ RPL + F+ + L T A+ + +Y N +
Sbjct: 458 ESWDFNIFELEAITHKRPLVYLGLKVFSRFGVCEFLNCSETTLRAWFQVIEANYHSSNAY 517
Query: 756 HNSLHAADVTQSTNVLL 806
HNS HAADV +T L
Sbjct: 518 HNSTHAADVLHATAFFL 534
>AY129950-2|AAN71726.1| 838|Homo sapiens cAMP-specific
phosphodiesterase 8B2 protein.
Length = 838
Score = 41.5 bits (93), Expect = 0.004
Identities = 22/77 (28%), Positives = 35/77 (45%)
Frame = +3
Query: 576 DRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPF 755
+ W +IF + ++ RPL + F+ + L T A+ + +Y N +
Sbjct: 508 ESWDFNIFELEAITHKRPLVYLGLKVFSRFGVCEFLNCSETTLRAWFQVIEANYHSSNAY 567
Query: 756 HNSLHAADVTQSTNVLL 806
HNS HAADV +T L
Sbjct: 568 HNSTHAADVLHATAFFL 584
>AY129950-1|AAN71725.1| 885|Homo sapiens cAMP-specific
phosphodiesterase 8B1 protein.
Length = 885
Score = 41.5 bits (93), Expect = 0.004
Identities = 22/77 (28%), Positives = 35/77 (45%)
Frame = +3
Query: 576 DRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPF 755
+ W +IF + ++ RPL + F+ + L T A+ + +Y N +
Sbjct: 555 ESWDFNIFELEAITHKRPLVYLGLKVFSRFGVCEFLNCSETTLRAWFQVIEANYHSSNAY 614
Query: 756 HNSLHAADVTQSTNVLL 806
HNS HAADV +T L
Sbjct: 615 HNSTHAADVLHATAFFL 631
>AY129949-1|AAN71724.1| 788|Homo sapiens cAMP-specific
phosphodiesterase 8B3 protein.
Length = 788
Score = 41.5 bits (93), Expect = 0.004
Identities = 22/77 (28%), Positives = 35/77 (45%)
Frame = +3
Query: 576 DRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPF 755
+ W +IF + ++ RPL + F+ + L T A+ + +Y N +
Sbjct: 458 ESWDFNIFELEAITHKRPLVYLGLKVFSRFGVCEFLNCSETTLRAWFQVIEANYHSSNAY 517
Query: 756 HNSLHAADVTQSTNVLL 806
HNS HAADV +T L
Sbjct: 518 HNSTHAADVLHATAFFL 534
>AY129948-1|AAN71723.1| 838|Homo sapiens cAMP-specific
phosphodiesterase 8B2 protein.
Length = 838
Score = 41.5 bits (93), Expect = 0.004
Identities = 22/77 (28%), Positives = 35/77 (45%)
Frame = +3
Query: 576 DRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPF 755
+ W +IF + ++ RPL + F+ + L T A+ + +Y N +
Sbjct: 508 ESWDFNIFELEAITHKRPLVYLGLKVFSRFGVCEFLNCSETTLRAWFQVIEANYHSSNAY 567
Query: 756 HNSLHAADVTQSTNVLL 806
HNS HAADV +T L
Sbjct: 568 HNSTHAADVLHATAFFL 584
>AL831924-1|CAD38584.1| 843|Homo sapiens hypothetical protein
protein.
Length = 843
Score = 41.5 bits (93), Expect = 0.004
Identities = 22/77 (28%), Positives = 35/77 (45%)
Frame = +3
Query: 576 DRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPF 755
+ W +IF + ++ RPL + F+ + L T A+ + +Y N +
Sbjct: 513 ESWDFNIFELEAITHKRPLVYLGLKVFSRFGVCEFLNCSETTLRAWFQVIEANYHSSNAY 572
Query: 756 HNSLHAADVTQSTNVLL 806
HNS HAADV +T L
Sbjct: 573 HNSTHAADVLHATAFFL 589
>AF079529-1|AAC69564.2| 885|Homo sapiens cAMP-specific
phosphodiesterase 8B1 protein.
Length = 885
Score = 41.5 bits (93), Expect = 0.004
Identities = 22/77 (28%), Positives = 35/77 (45%)
Frame = +3
Query: 576 DRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPF 755
+ W +IF + ++ RPL + F+ + L T A+ + +Y N +
Sbjct: 555 ESWDFNIFELEAITHKRPLVYLGLKVFSRFGVCEFLNCSETTLRAWFQVIEANYHSSNAY 614
Query: 756 HNSLHAADVTQSTNVLL 806
HNS HAADV +T L
Sbjct: 615 HNSTHAADVLHATAFFL 631
>AB085827-1|BAC53765.1| 865|Homo sapiens phosphodiesterase 8B4
protein.
Length = 865
Score = 41.5 bits (93), Expect = 0.004
Identities = 22/77 (28%), Positives = 35/77 (45%)
Frame = +3
Query: 576 DRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPF 755
+ W +IF + ++ RPL + F+ + L T A+ + +Y N +
Sbjct: 535 ESWDFNIFELEAITHKRPLVYLGLKVFSRFGVCEFLNCSETTLRAWFQVIEANYHSSNAY 594
Query: 756 HNSLHAADVTQSTNVLL 806
HNS HAADV +T L
Sbjct: 595 HNSTHAADVLHATAFFL 611
>AB085826-1|BAC53764.1| 830|Homo sapiens phosphodiesterase 8B3
protein.
Length = 830
Score = 41.5 bits (93), Expect = 0.004
Identities = 22/77 (28%), Positives = 35/77 (45%)
Frame = +3
Query: 576 DRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPF 755
+ W +IF + ++ RPL + F+ + L T A+ + +Y N +
Sbjct: 500 ESWDFNIFELEAITHKRPLVYLGLKVFSRFGVCEFLNCSETTLRAWFQVIEANYHSSNAY 559
Query: 756 HNSLHAADVTQSTNVLL 806
HNS HAADV +T L
Sbjct: 560 HNSTHAADVLHATAFFL 576
>AB085825-1|BAC53763.1| 788|Homo sapiens phosphodiestearse 8B2
protein.
Length = 788
Score = 41.5 bits (93), Expect = 0.004
Identities = 22/77 (28%), Positives = 35/77 (45%)
Frame = +3
Query: 576 DRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPF 755
+ W +IF + ++ RPL + F+ + L T A+ + +Y N +
Sbjct: 458 ESWDFNIFELEAITHKRPLVYLGLKVFSRFGVCEFLNCSETTLRAWFQVIEANYHSSNAY 517
Query: 756 HNSLHAADVTQSTNVLL 806
HNS HAADV +T L
Sbjct: 518 HNSTHAADVLHATAFFL 534
>AB085824-1|BAC53762.1| 885|Homo sapiens phosphodiesterase 8B1
protein.
Length = 885
Score = 41.5 bits (93), Expect = 0.004
Identities = 22/77 (28%), Positives = 35/77 (45%)
Frame = +3
Query: 576 DRWGVDIFRIGDLSCGRPLTAVAYTAFTSRELLTTLQIPARTFLAFAVTLXEHYIRDNPF 755
+ W +IF + ++ RPL + F+ + L T A+ + +Y N +
Sbjct: 555 ESWDFNIFELEAITHKRPLVYLGLKVFSRFGVCEFLNCSETTLRAWFQVIEANYHSSNAY 614
Query: 756 HNSLHAADVTQSTNVLL 806
HNS HAADV +T L
Sbjct: 615 HNSTHAADVLHATAFFL 631
>BC048317-1|AAH48317.1| 305|Homo sapiens PDE8A protein protein.
Length = 305
Score = 33.9 bits (74), Expect = 0.75
Identities = 14/48 (29%), Positives = 24/48 (50%)
Frame = +3
Query: 699 TFLAFAVTLXEHYIRDNPFHNSLHAADVTQSTNVLLNTPALNAVFTPL 842
T ++ + +Y NP+HNS H+ADV +T L+ + P+
Sbjct: 13 TLRSWLQIIEANYHSSNPYHNSTHSADVLHATAYFLSKERIKETLDPI 60
>U40584-1|AAB50018.1| 184|Homo sapiens
calcium/calmodulin-stimulated cyclic nucleotide
phosphodiesterase protein.
Length = 184
Score = 33.5 bits (73), Expect = 0.99
Identities = 12/20 (60%), Positives = 16/20 (80%)
Frame = +3
Query: 747 NPFHNSLHAADVTQSTNVLL 806
NP+HN +HAADVTQ+ + L
Sbjct: 20 NPYHNQIHAADVTQTVHCFL 39
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 118,251,920
Number of Sequences: 237096
Number of extensions: 2442121
Number of successful extensions: 5924
Number of sequences better than 10.0: 140
Number of HSP's better than 10.0 without gapping: 5530
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5831
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10705443456
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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