Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P09_F_E12
(839 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein. 432 e-121
BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenas... 432 e-121
BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein. 432 e-121
AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitr... 432 e-121
AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein. 432 e-121
CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein. 431 e-120
CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein. 431 e-120
BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein pr... 430 e-120
AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitra... 429 e-120
X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase... 404 e-112
BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenas... 404 e-112
BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenas... 404 e-112
AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenas... 402 e-112
DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenas... 392 e-109
U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase ... 357 3e-98
U62389-1|AAB17375.1| 154|Homo sapiens putative cytosolic NADP-d... 237 3e-62
BC020198-1|AAH20198.1| 567|Homo sapiens MEGF10 protein protein. 30 9.1
AB058676-1|BAB47409.1| 1140|Homo sapiens MEGF10 protein (KIAA178... 30 9.1
>CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 432 bits (1065), Expect = e-121
Identities = 197/266 (74%), Positives = 230/266 (86%), Gaps = 2/266 (0%)
Frame = +3
Query: 48 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 227
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 228 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 407
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 408 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 581
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 582 NTDASIIDFAHSSFKFALDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKKQFEDAG 761
N D SI DFAHSSF+ AL + +PLYLSTKNTILKKYDGRFKDIFQ+IYD++YK QFE
Sbjct: 184 NQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQK 243
Query: 762 IWYEHRLIDDMVAYAMKSXGGFVWAC 839
IWYEHRLIDDMVA AMKS GGF+WAC
Sbjct: 244 IWYEHRLIDDMVAQAMKSEGGFIWAC 269
>BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenase 1
(NADP+), soluble protein.
Length = 414
Score = 432 bits (1065), Expect = e-121
Identities = 197/266 (74%), Positives = 230/266 (86%), Gaps = 2/266 (0%)
Frame = +3
Query: 48 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 227
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 228 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 407
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 408 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 581
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 582 NTDASIIDFAHSSFKFALDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKKQFEDAG 761
N D SI DFAHSSF+ AL + +PLYLSTKNTILKKYDGRFKDIFQ+IYD++YK QFE
Sbjct: 184 NQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQK 243
Query: 762 IWYEHRLIDDMVAYAMKSXGGFVWAC 839
IWYEHRLIDDMVA AMKS GGF+WAC
Sbjct: 244 IWYEHRLIDDMVAQAMKSEGGFIWAC 269
>BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein.
Length = 414
Score = 432 bits (1065), Expect = e-121
Identities = 197/266 (74%), Positives = 230/266 (86%), Gaps = 2/266 (0%)
Frame = +3
Query: 48 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 227
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 228 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 407
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 408 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 581
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 582 NTDASIIDFAHSSFKFALDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKKQFEDAG 761
N D SI DFAHSSF+ AL + +PLYLSTKNTILKKYDGRFKDIFQ+IYD++YK QFE
Sbjct: 184 NQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQK 243
Query: 762 IWYEHRLIDDMVAYAMKSXGGFVWAC 839
IWYEHRLIDDMVA AMKS GGF+WAC
Sbjct: 244 IWYEHRLIDDMVAQAMKSEGGFIWAC 269
>AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 432 bits (1065), Expect = e-121
Identities = 197/266 (74%), Positives = 230/266 (86%), Gaps = 2/266 (0%)
Frame = +3
Query: 48 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 227
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 228 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 407
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 408 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 581
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 582 NTDASIIDFAHSSFKFALDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKKQFEDAG 761
N D SI DFAHSSF+ AL + +PLYLSTKNTILKKYDGRFKDIFQ+IYD++YK QFE
Sbjct: 184 NQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQK 243
Query: 762 IWYEHRLIDDMVAYAMKSXGGFVWAC 839
IWYEHRLIDDMVA AMKS GGF+WAC
Sbjct: 244 IWYEHRLIDDMVAQAMKSEGGFIWAC 269
>AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein.
Length = 414
Score = 432 bits (1065), Expect = e-121
Identities = 197/266 (74%), Positives = 230/266 (86%), Gaps = 2/266 (0%)
Frame = +3
Query: 48 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 227
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 228 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 407
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 408 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 581
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 582 NTDASIIDFAHSSFKFALDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKKQFEDAG 761
N D SI DFAHSSF+ AL + +PLYLSTKNTILKKYDGRFKDIFQ+IYD++YK QFE
Sbjct: 184 NQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQK 243
Query: 762 IWYEHRLIDDMVAYAMKSXGGFVWAC 839
IWYEHRLIDDMVA AMKS GGF+WAC
Sbjct: 244 IWYEHRLIDDMVAQAMKSEGGFIWAC 269
>CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 431 bits (1063), Expect = e-120
Identities = 196/266 (73%), Positives = 231/266 (86%), Gaps = 2/266 (0%)
Frame = +3
Query: 48 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 227
KI G VV++ GDEMTRIIW+LIKEKLI+P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIIPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 228 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 407
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 408 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 581
W +PIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVEPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 582 NTDASIIDFAHSSFKFALDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKKQFEDAG 761
N D SI DFAHSSF+ AL + +PLYLSTKNTILKKYDGRFKDIFQ+IYD++YK QFE
Sbjct: 184 NQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQK 243
Query: 762 IWYEHRLIDDMVAYAMKSXGGFVWAC 839
IWYEHRLIDDMVA AMKS GGF+WAC
Sbjct: 244 IWYEHRLIDDMVAQAMKSEGGFIWAC 269
>CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 431 bits (1062), Expect = e-120
Identities = 196/266 (73%), Positives = 230/266 (86%), Gaps = 2/266 (0%)
Frame = +3
Query: 48 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 227
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 228 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 407
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 408 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 581
W KPIIIGRHA+ DQY+ATDFVVPG G +E+ + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEMTYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 582 NTDASIIDFAHSSFKFALDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKKQFEDAG 761
N D SI DFAHSSF+ AL + +PLYLSTKNTILKKYDGRFKDIFQ+IYD++YK QFE
Sbjct: 184 NQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQK 243
Query: 762 IWYEHRLIDDMVAYAMKSXGGFVWAC 839
IWYEHRLIDDMVA AMKS GGF+WAC
Sbjct: 244 IWYEHRLIDDMVAQAMKSEGGFIWAC 269
>BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein
protein.
Length = 414
Score = 430 bits (1060), Expect = e-120
Identities = 197/266 (74%), Positives = 229/266 (86%), Gaps = 2/266 (0%)
Frame = +3
Query: 48 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 227
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 228 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 407
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 408 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEYK-GAGVALAMF 581
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNSEGGGGVAMGMY 183
Query: 582 NTDASIIDFAHSSFKFALDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKKQFEDAG 761
N D SI DFAHSSF+ AL + +PLYLSTKNTILKKYDGRFKDIFQ+IYD++YK QFE
Sbjct: 184 NQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQK 243
Query: 762 IWYEHRLIDDMVAYAMKSXGGFVWAC 839
IWYEHRLIDDMVA AMKS GGF+WAC
Sbjct: 244 IWYEHRLIDDMVAQAMKSEGGFIWAC 269
>AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 429 bits (1057), Expect = e-120
Identities = 196/266 (73%), Positives = 229/266 (86%), Gaps = 2/266 (0%)
Frame = +3
Query: 48 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 227
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 228 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 407
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 408 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 581
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 582 NTDASIIDFAHSSFKFALDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKKQFEDAG 761
N D SI DFAHSSF+ AL + +PLYLSTKNTILK YDGRFKDIFQ+IYD++YK QFE
Sbjct: 184 NQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKIYDGRFKDIFQEIYDKQYKSQFEAQK 243
Query: 762 IWYEHRLIDDMVAYAMKSXGGFVWAC 839
IWYEHRLIDDMVA AMKS GGF+WAC
Sbjct: 244 IWYEHRLIDDMVAQAMKSEGGFIWAC 269
>X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase
(NADP+) protein.
Length = 452
Score = 404 bits (995), Expect = e-112
Identities = 186/275 (67%), Positives = 218/275 (79%), Gaps = 2/275 (0%)
Frame = +3
Query: 21 YSRHRYNMSKIK-AGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTD 197
+ R Y +IK A PVV++ GDEMTRIIW IKEKLILP +DI+L +DLG+ NRD+TD
Sbjct: 34 HPRRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTD 93
Query: 198 DQVTIDCAEAIKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAII 377
DQVTID A A +KY+V +KCATITPDE RVEEFKLKKMWKSPNGTIRNILGGTVFRE II
Sbjct: 94 DQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPII 153
Query: 378 CKNIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESGEAIKH-VVHEYK 554
CKNIPRLV GW KPI IGRHAH DQYKATDFV AGT +++F P+ G +K V+ +
Sbjct: 154 CKNIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFP 213
Query: 555 GAGVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDRE 734
GV + M+NTD SI FAHS F++A+ +K+PLY+STKNTILK YDGRFKDIFQ+I+D+
Sbjct: 214 AGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKH 273
Query: 735 YKKQFEDAGIWYEHRLIDDMVAYAMKSXGGFVWAC 839
YK F+ IWYEHRLIDDMVA +KS GGFVWAC
Sbjct: 274 YKTDFDKNKIWYEHRLIDDMVAQVLKSSGGFVWAC 308
>BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 404 bits (994), Expect = e-112
Identities = 186/273 (68%), Positives = 217/273 (79%), Gaps = 2/273 (0%)
Frame = +3
Query: 27 RHRYNMSKIK-AGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQ 203
R Y +IK A PVV++ GDEMTRIIW IKEKLILP +DI+L +DLG+ NRD+TDDQ
Sbjct: 36 RRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQ 95
Query: 204 VTIDCAEAIKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICK 383
VTID A A +KY+V +KCATITPDE RVEEFKLKKMWKSPNGTIRNILGGTVFRE IICK
Sbjct: 96 VTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICK 155
Query: 384 NIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESGEAIKH-VVHEYKGA 560
NIPRLV GW KPI IGRHAH DQYKATDFV AGT +++F P+ G +K V+ +
Sbjct: 156 NIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAG 215
Query: 561 GVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYK 740
GV + M+NTD SI FAHS F++A+ +K+PLY+STKNTILK YDGRFKDIFQ+I+D+ YK
Sbjct: 216 GVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYK 275
Query: 741 KQFEDAGIWYEHRLIDDMVAYAMKSXGGFVWAC 839
F+ IWYEHRLIDDMVA +KS GGFVWAC
Sbjct: 276 TDFDKNKIWYEHRLIDDMVAQVLKSSGGFVWAC 308
>BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 404 bits (994), Expect = e-112
Identities = 186/273 (68%), Positives = 217/273 (79%), Gaps = 2/273 (0%)
Frame = +3
Query: 27 RHRYNMSKIK-AGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQ 203
R Y +IK A PVV++ GDEMTRIIW IKEKLILP +DI+L +DLG+ NRD+TDDQ
Sbjct: 36 RRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQ 95
Query: 204 VTIDCAEAIKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICK 383
VTID A A +KY+V +KCATITPDE RVEEFKLKKMWKSPNGTIRNILGGTVFRE IICK
Sbjct: 96 VTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICK 155
Query: 384 NIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESGEAIKH-VVHEYKGA 560
NIPRLV GW KPI IGRHAH DQYKATDFV AGT +++F P+ G +K V+ +
Sbjct: 156 NIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAG 215
Query: 561 GVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYK 740
GV + M+NTD SI FAHS F++A+ +K+PLY+STKNTILK YDGRFKDIFQ+I+D+ YK
Sbjct: 216 GVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYK 275
Query: 741 KQFEDAGIWYEHRLIDDMVAYAMKSXGGFVWAC 839
F+ IWYEHRLIDDMVA +KS GGFVWAC
Sbjct: 276 TDFDKNKIWYEHRLIDDMVAQVLKSSGGFVWAC 308
>AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial precursor variant protein.
Length = 452
Score = 402 bits (990), Expect = e-112
Identities = 185/273 (67%), Positives = 217/273 (79%), Gaps = 2/273 (0%)
Frame = +3
Query: 27 RHRYNMSKIK-AGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQ 203
R Y +IK A PVV++ GDEMTRIIW IKEKLILP +DI+L +DLG+ NRD+TDDQ
Sbjct: 36 RRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQ 95
Query: 204 VTIDCAEAIKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICK 383
VTID A A +KY+V +KCATITPDE RVEEFKLKKMWKSPNGTIRNILGGTVFRE IICK
Sbjct: 96 VTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICK 155
Query: 384 NIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESGEAIKH-VVHEYKGA 560
NIPRLV GW KPI IGRHAH DQYKATDFV AGT +++F P+ G +K V+ +
Sbjct: 156 NIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAG 215
Query: 561 GVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYK 740
GV + M+NTD SI FAHS F++A+ +K+PLY+STKNTILK YDGRFKDIFQ+I+D+ Y+
Sbjct: 216 GVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYE 275
Query: 741 KQFEDAGIWYEHRLIDDMVAYAMKSXGGFVWAC 839
F+ IWYEHRLIDDMVA +KS GGFVWAC
Sbjct: 276 TDFDKNKIWYEHRLIDDMVAQVLKSSGGFVWAC 308
>DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenase 1
protein.
Length = 371
Score = 392 bits (966), Expect = e-109
Identities = 178/240 (74%), Positives = 208/240 (86%), Gaps = 2/240 (0%)
Frame = +3
Query: 126 LILPFLDIELHVYDLGMENRDKTDDQVTIDCAEAIKKYNVGIKCATITPDEKRVEEFKLK 305
LI P+++++LH YDLG+ENRD T+DQVT D AEAIKK+NVG+KCATITPDEKRVEEFKLK
Sbjct: 1 LIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLK 60
Query: 306 KMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGA 485
+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+GW KPIIIGRHA+ DQY+ATDFVVPG
Sbjct: 61 QMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGP 120
Query: 486 GTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMFNTDASIIDFAHSSFKFALDRKYPLYL 659
G +EI + P G + + ++VH + +G GVA+ M+N D SI DFAHSSF+ AL + +PLYL
Sbjct: 121 GKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYL 180
Query: 660 STKNTILKKYDGRFKDIFQDIYDREYKKQFEDAGIWYEHRLIDDMVAYAMKSXGGFVWAC 839
STKNTILKKYDGRFKDIFQ+IYD++YK QFE IWYEHRLIDDMVA AMKS GGF+WAC
Sbjct: 181 STKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWAC 240
>U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase
protein.
Length = 419
Score = 357 bits (878), Expect = 3e-98
Identities = 160/234 (68%), Positives = 188/234 (80%), Gaps = 1/234 (0%)
Frame = +3
Query: 141 LDIELHVYDLGMENRDKTDDQVTIDCAEAIKKYNVGIKCATITPDEKRVEEFKLKKMWKS 320
LD++L +DLG+ NRD+TDDQVTID A A +KY+V +KCATITPDE RVEEFKLKKMWKS
Sbjct: 42 LDVQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKS 101
Query: 321 PNGTIRNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEI 500
PNGTIRNI GGTVFRE IICKNIPRLV GW KPI IGRHAH DQYKATDFV AGT ++
Sbjct: 102 PNGTIRNIHGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKM 161
Query: 501 IFKPESGEAIKH-VVHEYKGAGVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTI 677
+F P+ G +K V+ + GV + M+NTD SI FAHS F++A+ +K+PLY+STKNTI
Sbjct: 162 VFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTI 221
Query: 678 LKKYDGRFKDIFQDIYDREYKKQFEDAGIWYEHRLIDDMVAYAMKSXGGFVWAC 839
LK YDGRFKDIFQ+I+D+ YK F+ IWYEHRLIDDMVA +KS GGFVWAC
Sbjct: 222 LKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGFVWAC 275
>U62389-1|AAB17375.1| 154|Homo sapiens putative cytosolic
NADP-dependent isocitrate dehydrogenase protein.
Length = 154
Score = 237 bits (581), Expect = 3e-62
Identities = 109/154 (70%), Positives = 128/154 (83%), Gaps = 2/154 (1%)
Frame = +3
Query: 336 RNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPE 515
RNILGGTVF EAIICKNIPRLV+GW KPIIIGRHA+ DQY+ATDFVVPG G +EI + P
Sbjct: 1 RNILGGTVFXEAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPS 60
Query: 516 SG-EAIKHVVHEYK-GAGVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTILKKY 689
G + + ++VH ++ G GVA+ M+N D SI DFAHSSF+ AL + +PLYLSTKNTILKKY
Sbjct: 61 DGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKY 120
Query: 690 DGRFKDIFQDIYDREYKKQFEDAGIWYEHRLIDD 791
DGRFKDIFQ+IYD++YK QFE IWYEHRLIDD
Sbjct: 121 DGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDD 154
>BC020198-1|AAH20198.1| 567|Homo sapiens MEGF10 protein protein.
Length = 567
Score = 30.3 bits (65), Expect = 9.1
Identities = 21/68 (30%), Positives = 24/68 (35%), Gaps = 3/68 (4%)
Frame = +2
Query: 398 CNRVGQTHHHWTSCSC*SIQSN*LC---CPRCWYS*NNLQT*IW*GNKTCSS*VQGCRCS 568
C G HH CSC S +C CP + N Q TC + C CS
Sbjct: 240 CQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCS 299
Query: 569 TGYV*H*C 592
GY C
Sbjct: 300 PGYTGERC 307
>AB058676-1|BAB47409.1| 1140|Homo sapiens MEGF10 protein (KIAA1780)
protein.
Length = 1140
Score = 30.3 bits (65), Expect = 9.1
Identities = 21/68 (30%), Positives = 24/68 (35%), Gaps = 3/68 (4%)
Frame = +2
Query: 398 CNRVGQTHHHWTSCSC*SIQSN*LC---CPRCWYS*NNLQT*IW*GNKTCSS*VQGCRCS 568
C G HH CSC S +C CP + N Q TC + C CS
Sbjct: 240 CQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCS 299
Query: 569 TGYV*H*C 592
GY C
Sbjct: 300 PGYTGERC 307
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 125,888,513
Number of Sequences: 237096
Number of extensions: 2743607
Number of successful extensions: 5161
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 4843
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5139
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10593928420
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -