Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P09_F_C17
(750 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI00015B60D2 Cluster: PREDICTED: similar to ENSANGP000... 254 2e-66
UniRef50_Q9VC92 Cluster: CG6432-PA; n=7; cellular organisms|Rep:... 230 2e-59
UniRef50_A7RH51 Cluster: Predicted protein; n=1; Nematostella ve... 212 9e-54
UniRef50_UPI0000E4931E Cluster: PREDICTED: hypothetical protein,... 202 1e-50
UniRef50_Q9H6R3 Cluster: CDNA: FLJ21963 fis, clone HEP05583; n=3... 200 2e-50
UniRef50_O67872 Cluster: Acetyl-coenzyme A synthetase; n=5; cell... 168 1e-40
UniRef50_P28812 Cluster: Uncharacterized protein PA3568; n=81; c... 166 4e-40
UniRef50_Q871W2 Cluster: Related to acetyl coenzyme A synthetase... 161 2e-38
UniRef50_Q4WAZ5 Cluster: Acetate-CoA ligase, putative; n=1; Aspe... 160 4e-38
UniRef50_Q5QYS0 Cluster: Propionyl-CoA synthetase; n=1; Idiomari... 159 7e-38
UniRef50_Q55404 Cluster: Acetyl-coenzyme A synthetase; n=89; cel... 159 9e-38
UniRef50_P55912 Cluster: Propionate--CoA ligase; n=57; Bacteria|... 158 1e-37
UniRef50_A2TC85 Cluster: AMP-dependent synthetase and ligase; n=... 157 2e-37
UniRef50_Q82EL5 Cluster: Acetyl-coenzyme A synthetase; n=28; cel... 157 4e-37
UniRef50_A5UUT7 Cluster: Acetate--CoA ligase; n=2; Roseiflexus|R... 155 8e-37
UniRef50_A1CSK5 Cluster: Acyl-CoA synthetase, putative; n=7; Pez... 152 1e-35
UniRef50_A5WC66 Cluster: Propionate--CoA ligase; n=3; Psychrobac... 150 3e-35
UniRef50_Q247U0 Cluster: AMP-binding enzyme family protein; n=1;... 147 3e-34
UniRef50_Q22UI3 Cluster: AMP-binding enzyme family protein; n=6;... 146 7e-34
UniRef50_Q869S4 Cluster: Similar to Bradyrhizobium japonicum. Ac... 144 2e-33
UniRef50_Q0I9W4 Cluster: Acetate--CoA ligase; n=19; cellular org... 143 5e-33
UniRef50_Q01L46 Cluster: H0502B11.5 protein; n=5; Magnoliophyta|... 142 6e-33
UniRef50_O93730 Cluster: Acetyl-coenzyme A synthetase; n=11; Arc... 142 1e-32
UniRef50_Q8YJ48 Cluster: Acetyl-coenzyme A synthetase; n=48; cel... 140 3e-32
UniRef50_Q0JDG8 Cluster: Os04g0404800 protein; n=8; cellular org... 138 1e-31
UniRef50_Q7S7A6 Cluster: Putative uncharacterized protein NCU014... 136 4e-31
UniRef50_Q89WV5 Cluster: Acetyl-coenzyme A synthetase; n=105; Ba... 136 7e-31
UniRef50_A7ATQ7 Cluster: Acetyl-CoA synthetase, putative; n=1; B... 134 2e-30
UniRef50_Q4J9J7 Cluster: Acetyl-coenzyme A synthetase; n=4; Sulf... 134 2e-30
UniRef50_Q8KBY0 Cluster: Acetyl-coenzyme A synthetase; n=44; cel... 134 2e-30
UniRef50_O25686 Cluster: Acetyl-coenzyme A synthetase; n=40; Bac... 134 3e-30
UniRef50_Q8EYG2 Cluster: Acetyl-coenzyme A synthetase; n=76; cel... 133 4e-30
UniRef50_Q9PMD2 Cluster: Acetyl-coenzyme A synthetase; n=143; ce... 131 2e-29
UniRef50_P27095 Cluster: Acetyl-coenzyme A synthetase; n=12; cel... 129 8e-29
UniRef50_A7HB74 Cluster: AMP-dependent synthetase and ligase; n=... 128 1e-28
UniRef50_Q8ZV36 Cluster: Acetyl-coenzyme A synthetase; n=4; Pyro... 128 1e-28
UniRef50_Q978X5 Cluster: Acetyl-CoA synthetase; n=3; cellular or... 126 4e-28
UniRef50_Q2RGI0 Cluster: Acetyl-coenzyme A synthetase; n=1; Moor... 125 1e-27
UniRef50_Q01574 Cluster: Acetyl-coenzyme A synthetase 1; n=40; F... 125 1e-27
UniRef50_Q67QN3 Cluster: Acetyl-coenzyme A synthetase; n=6; Bact... 124 2e-27
UniRef50_Q01CP6 Cluster: Acyl-CoA synthetase; n=6; Eukaryota|Rep... 124 2e-27
UniRef50_A6G1J4 Cluster: Acetate--CoA ligase; n=1; Plesiocystis ... 120 4e-26
UniRef50_Q7RL40 Cluster: Acetate--CoA ligase-related; n=3; Plasm... 119 7e-26
UniRef50_Q27549 Cluster: Acetyl-coenzyme A synthetase; n=7; Apic... 119 7e-26
UniRef50_A2E702 Cluster: AMP-binding enzyme family protein; n=2;... 119 9e-26
UniRef50_Q6LEZ6 Cluster: Acetyl-coenzyme a synthetase; n=3; Plas... 117 3e-25
UniRef50_Q9HQU8 Cluster: Acetyl-CoA synthetase; n=11; root|Rep: ... 117 3e-25
UniRef50_Q75JX6 Cluster: Similar to Vibrio cholerae. PrpE protei... 115 1e-24
UniRef50_Q81Q80 Cluster: Acetoacetyl-CoA synthase, putative; n=1... 113 3e-24
UniRef50_Q9NUB1 Cluster: Acetyl-coenzyme A synthetase 2-like, mi... 113 3e-24
UniRef50_Q5BYW0 Cluster: SJCHGC03435 protein; n=1; Schistosoma j... 112 8e-24
UniRef50_Q4PHQ0 Cluster: Putative uncharacterized protein; n=1; ... 112 8e-24
UniRef50_Q9NR19 Cluster: Acetyl-coenzyme A synthetase, cytoplasm... 112 8e-24
UniRef50_Q557A3 Cluster: Putative uncharacterized protein; n=2; ... 111 2e-23
UniRef50_Q86AI5 Cluster: Similar to Bradyrhizobium japonicum. Ac... 110 3e-23
UniRef50_Q127M4 Cluster: AMP-dependent synthetase and ligase; n=... 109 5e-23
UniRef50_A5K2B0 Cluster: Acetyl-CoA synthetase, putative; n=1; P... 109 9e-23
UniRef50_UPI0000382F9A Cluster: COG0365: Acyl-coenzyme A synthet... 108 1e-22
UniRef50_Q5FTV0 Cluster: Acetyl-coenzyme A synthetase; n=1; Gluc... 106 7e-22
UniRef50_Q8SRZ9 Cluster: ACETYLCOENZYME A SYNTHETASE; n=1; Encep... 105 9e-22
UniRef50_Q55GU6 Cluster: Putative acetyl-CoA synthetase; n=3; Di... 105 1e-21
UniRef50_Q97WQ9 Cluster: Acetyl-CoA synthetase; n=3; Sulfolobus|... 105 1e-21
UniRef50_Q72J94 Cluster: Acetyl-coenzyme A synthetase; n=2; Ther... 105 2e-21
UniRef50_Q54YU1 Cluster: Putative uncharacterized protein; n=1; ... 105 2e-21
UniRef50_Q93LL2 Cluster: Acetyl-coenzyme A synthetase; n=165; ce... 105 2e-21
UniRef50_A1S0M6 Cluster: AMP-dependent synthetase and ligase; n=... 104 2e-21
UniRef50_A4A7V6 Cluster: Acetyl-coenzyme A synthetase/GroES-like... 103 4e-21
UniRef50_Q6U666 Cluster: Putative uncharacterized protein; n=1; ... 103 5e-21
UniRef50_Q8ZUB3 Cluster: Acetyl-coenzyme A synthetase; n=4; Arch... 103 6e-21
UniRef50_A4WKF4 Cluster: AMP-dependent synthetase and ligase; n=... 101 1e-20
UniRef50_Q9RX55 Cluster: Acetyl-CoA synthase; n=4; cellular orga... 100 3e-20
UniRef50_Q9HLJ9 Cluster: Acetyl-CoA synthetase related protein; ... 100 4e-20
UniRef50_Q140P4 Cluster: Putative acetyl-CoA synthetase and liga... 99 6e-20
UniRef50_Q5P1M8 Cluster: Acyl-CoA synthetase; n=2; Azoarcus|Rep:... 100 8e-20
UniRef50_Q1JYJ4 Cluster: AMP-dependent synthetase and ligase; n=... 99 1e-19
UniRef50_Q0FW37 Cluster: Acyl-CoA synthetase; n=1; Roseovarius s... 99 1e-19
UniRef50_Q39MW7 Cluster: AMP-dependent synthetase and ligase; n=... 98 2e-19
UniRef50_Q4QBC0 Cluster: Acetyl-CoA synthetase, putative; n=6; E... 98 2e-19
UniRef50_A7DME3 Cluster: AMP-dependent synthetase and ligase; n=... 98 2e-19
UniRef50_Q9YCA8 Cluster: Acetyl-coenzyme A synthetase; n=2; Arch... 97 4e-19
UniRef50_Q6L1R5 Cluster: Acetyl-coenzyme A synthetase; n=1; Picr... 97 4e-19
UniRef50_A3VFU7 Cluster: Acetoacetyl-CoA synthase; n=1; Rhodobac... 94 3e-18
UniRef50_Q9Y8M8 Cluster: Acetyl-coenzyme A synthetase; n=1; Aero... 94 4e-18
UniRef50_Q5V498 Cluster: Acyl-coenzyme A synthetases; n=5; Halob... 92 1e-17
UniRef50_Q97WK0 Cluster: Acetyl-CoA synthetase; n=4; Sulfolobace... 90 5e-17
UniRef50_Q4ST59 Cluster: Chromosome undetermined SCAF14300, whol... 89 8e-17
UniRef50_Q3E187 Cluster: AMP-dependent synthetase and ligase:Eno... 89 1e-16
UniRef50_A3WE14 Cluster: Acetyl-coenzyme A synthetase; n=1; Eryt... 85 2e-15
UniRef50_O30042 Cluster: Acetyl-CoA synthetase; n=1; Archaeoglob... 85 2e-15
UniRef50_Q0RXR5 Cluster: Acetate--CoA ligase; n=1; Rhodococcus s... 84 3e-15
UniRef50_A5UY60 Cluster: AMP-dependent synthetase and ligase; n=... 84 3e-15
UniRef50_A7JC22 Cluster: Predicted protein; n=1; Francisella tul... 83 5e-15
UniRef50_Q397N8 Cluster: Acetoacetyl-CoA synthase; n=5; Bacteria... 83 9e-15
UniRef50_A4T5I6 Cluster: Acetoacetyl-CoA synthase; n=2; Mycobact... 81 4e-14
UniRef50_Q54YU2 Cluster: Putative uncharacterized protein; n=1; ... 80 7e-14
UniRef50_Q9KZN9 Cluster: Acetoacetyl-CoA synthetase; n=5; Actino... 79 9e-14
UniRef50_Q01NM8 Cluster: AMP-dependent synthetase and ligase; n=... 79 9e-14
UniRef50_A3W6I7 Cluster: AMP-dependent synthetase and ligase; n=... 77 4e-13
UniRef50_Q12HA7 Cluster: Acetoacetyl-CoA synthase precursor; n=6... 76 8e-13
UniRef50_A5WDS3 Cluster: AMP-dependent synthetase and ligase; n=... 75 2e-12
UniRef50_Q86JR9 Cluster: Putative uncharacterized protein; n=2; ... 75 2e-12
UniRef50_UPI00005102FE Cluster: COG0365: Acyl-coenzyme A synthet... 74 3e-12
UniRef50_Q5KZW6 Cluster: Acetoacetyl-CoA synthetase; n=20; Bacte... 72 1e-11
UniRef50_P39062 Cluster: Acetyl-coenzyme A synthetase; n=41; cel... 72 2e-11
UniRef50_A4QIB2 Cluster: Putative uncharacterized protein; n=1; ... 71 3e-11
UniRef50_O28347 Cluster: Long-chain-fatty-acid--CoA ligase; n=1;... 70 5e-11
UniRef50_A1IEB0 Cluster: Acetoacetyl-CoA synthase; n=1; Candidat... 69 9e-11
UniRef50_Q8ZV30 Cluster: Acetyl-coenzyme A synthetase; n=6; Ther... 69 1e-10
UniRef50_Q0S3K9 Cluster: Acetoacetate--CoA ligase; n=10; Actinom... 69 2e-10
UniRef50_Q8IWD2 Cluster: Acetoacetyl-CoA synthetase; n=53; Eumet... 68 2e-10
UniRef50_A1W234 Cluster: Acetoacetyl-CoA synthase; n=2; Comamona... 67 5e-10
UniRef50_A1VP64 Cluster: Acetoacetyl-CoA synthase; n=2; Comamona... 67 5e-10
UniRef50_Q8ESW2 Cluster: Acetoacetyl-CoA synthetase; n=1; Oceano... 66 7e-10
UniRef50_Q0A597 Cluster: AMP-dependent synthetase and ligase; n=... 66 7e-10
UniRef50_Q0SJB1 Cluster: Acetoacetate--CoA ligase; n=1; Rhodococ... 66 1e-09
UniRef50_A4TUE0 Cluster: Acyl-coenzyme A synthetases/AMP-(Fatty)... 65 2e-09
UniRef50_Q8F6X6 Cluster: Acetyl-CoA synthetase; n=3; Bacteria|Re... 64 4e-09
UniRef50_A4TEH9 Cluster: Acetyl-CoA synthetase precursor; n=1; M... 64 4e-09
UniRef50_A0JS90 Cluster: AMP-dependent synthetase and ligase; n=... 64 5e-09
UniRef50_A7IGG1 Cluster: AMP-dependent synthetase and ligase; n=... 63 6e-09
UniRef50_A3JB96 Cluster: Acetyl-coenzyme A synthetase; n=6; Gamm... 63 6e-09
UniRef50_Q2J785 Cluster: Acetoacetyl-CoA synthase; n=5; Actinoba... 62 1e-08
UniRef50_Q7W0W3 Cluster: Acetyl-CoA synthetase; n=2; Bordetella|... 62 2e-08
UniRef50_Q11QU1 Cluster: Acetyl-CoA synthetase; n=1; Cytophaga h... 61 2e-08
UniRef50_Q5KW92 Cluster: Acetyl-CoA synthetase; n=2; Geobacillus... 61 3e-08
UniRef50_Q39MD9 Cluster: AMP-dependent synthetase and ligase; n=... 61 3e-08
UniRef50_A6C4K4 Cluster: Acetate--CoA ligase; n=1; Planctomyces ... 60 4e-08
UniRef50_Q5UWB7 Cluster: Acyl-coenzyme A synthetases; n=2; Halob... 60 4e-08
UniRef50_Q7WPR9 Cluster: AMP-binding enzyme; n=5; Burkholderiale... 60 8e-08
UniRef50_Q5P869 Cluster: 3-hydroxybenzoate CoA ligase; n=2; Rhod... 59 1e-07
UniRef50_A4FEF5 Cluster: AMP-dependent synthetase and ligase; n=... 58 3e-07
UniRef50_A2SSU3 Cluster: AMP-dependent synthetase and ligase; n=... 57 5e-07
UniRef50_A6QV87 Cluster: Putative uncharacterized protein; n=2; ... 56 7e-07
UniRef50_A0KEL2 Cluster: Acetoacetyl-CoA synthase; n=2; Aeromona... 56 9e-07
UniRef50_UPI0000510398 Cluster: COG0365: Acyl-coenzyme A synthet... 56 1e-06
UniRef50_Q7WNN5 Cluster: Putative long-chain-fatty-acid-CoA liga... 55 2e-06
UniRef50_A6FGF6 Cluster: Probable AMP-binding enzyme; n=1; Morit... 55 2e-06
UniRef50_Q83DG9 Cluster: Acetoacetyl-CoA synthase; n=5; Gammapro... 54 3e-06
UniRef50_UPI000038E2AC Cluster: hypothetical protein Faci_030001... 54 4e-06
UniRef50_Q11M02 Cluster: Acetoacetyl-CoA synthase; n=7; Proteoba... 54 4e-06
UniRef50_Q6MYU7 Cluster: Acetoacetyl-coa synthetase, putative; n... 54 4e-06
UniRef50_Q3IUK7 Cluster: Acyl-CoA synthetase I 5; n=2; Halobacte... 54 4e-06
UniRef50_Q8YBS1 Cluster: ACETYL-COENZYME A SYNTHETASE; n=38; Pro... 53 7e-06
UniRef50_Q8G3C8 Cluster: Acetoacetyl-CoA synthase; n=36; Proteob... 52 2e-05
UniRef50_Q7NVV9 Cluster: Synthetase CbsF; n=3; cellular organism... 52 2e-05
UniRef50_Q0RL93 Cluster: Putative uncharacterized protein; n=1; ... 52 2e-05
UniRef50_A5UV13 Cluster: AMP-dependent synthetase and ligase; n=... 52 2e-05
UniRef50_A1SEZ8 Cluster: AMP-dependent synthetase and ligase; n=... 52 2e-05
UniRef50_Q21UY9 Cluster: AMP-dependent synthetase and ligase; n=... 52 2e-05
UniRef50_A7I4G3 Cluster: AMP-dependent synthetase and ligase; n=... 52 2e-05
UniRef50_Q5KZW0 Cluster: Long-chain fatty-acid-CoA ligase; n=6; ... 51 3e-05
UniRef50_A2QQX9 Cluster: Contig An08c0110, complete genome; n=6;... 51 3e-05
UniRef50_A1UDV2 Cluster: AMP-dependent synthetase and ligase; n=... 51 4e-05
UniRef50_A0Y863 Cluster: Long-chain fatty acid--CoA ligase; n=1;... 51 4e-05
UniRef50_Q0LLG2 Cluster: Amino acid adenylation; n=1; Herpetosip... 50 5e-05
UniRef50_A4X9C6 Cluster: Thioester reductase domain; n=2; Salini... 50 5e-05
UniRef50_Q87H07 Cluster: Acetyl-CoA synthase; n=13; Vibrionales|... 50 6e-05
UniRef50_Q47NR9 Cluster: Non-ribosomal peptide synthase:Amino ac... 50 6e-05
UniRef50_Q50E73 Cluster: Peptide synthetase 2; n=1; Streptomyces... 50 6e-05
UniRef50_Q0S4D9 Cluster: CoA ligase; n=2; Nocardiaceae|Rep: CoA ... 50 6e-05
UniRef50_Q2H9I4 Cluster: Putative uncharacterized protein; n=1; ... 50 6e-05
UniRef50_P27096 Cluster: Uncharacterized 16.9 kDa protein in acs... 50 6e-05
UniRef50_Q45R83 Cluster: Peptide synthetase; n=3; Actinobacteria... 50 8e-05
UniRef50_Q06YZ2 Cluster: Nonribosomal peptide synthetase; n=1; S... 50 8e-05
UniRef50_A0Z3I7 Cluster: Acyl-CoA synthase; n=1; marine gamma pr... 50 8e-05
UniRef50_A0LK08 Cluster: AMP-dependent synthetase and ligase; n=... 50 8e-05
UniRef50_Q2NH56 Cluster: Predicted acyl-CoA synthetase; n=1; Met... 50 8e-05
UniRef50_Q39T59 Cluster: AMP-dependent synthetase and ligase; n=... 49 1e-04
UniRef50_Q3WFP5 Cluster: AMP-dependent synthetase and ligase; n=... 49 1e-04
UniRef50_Q6L1D6 Cluster: Long chain fatty acid CoA ligase; n=1; ... 49 1e-04
UniRef50_Q18HL6 Cluster: O-succinylbenzoic acid--CoA ligase; n=1... 49 1e-04
UniRef50_Q9Z3R3 Cluster: Acetoacetyl-coenzyme A synthetase; n=7;... 49 1e-04
UniRef50_Q1GUE8 Cluster: AMP-dependent synthetase and ligase; n=... 48 2e-04
UniRef50_A0LLK9 Cluster: Benzoate-CoA ligase family; n=1; Syntro... 48 2e-04
UniRef50_Q6KZU2 Cluster: Acetoacetyl-CoA synthetase; n=1; Picrop... 48 2e-04
UniRef50_Q9KLB7 Cluster: Acetyl-CoA synthase; n=21; Vibrio|Rep: ... 48 2e-04
UniRef50_Q3IWF1 Cluster: AMP-binding enzyme; n=6; Alphaproteobac... 48 2e-04
UniRef50_Q13BW2 Cluster: AMP-dependent synthetase and ligase; n=... 48 2e-04
UniRef50_Q0SGL4 Cluster: AMP-dependent synthetase; n=1; Rhodococ... 48 2e-04
UniRef50_Q6A9A4 Cluster: Acetyl-coenzyme A synthetase; n=1; Prop... 48 3e-04
UniRef50_Q5D0Q8 Cluster: Nonribosomal peptide synthetase 10; n=1... 48 3e-04
UniRef50_Q0D0Z7 Cluster: Putative uncharacterized protein; n=2; ... 48 3e-04
UniRef50_Q70C44 Cluster: Non-ribosomal peptide synthase; n=1; Xa... 47 4e-04
UniRef50_Q21EY1 Cluster: Amino acid adenylation; n=1; Saccharoph... 47 4e-04
UniRef50_Q124C5 Cluster: AMP-dependent synthetase and ligase; n=... 47 4e-04
UniRef50_Q0S7A8 Cluster: 2,3-dihydroxybenzoate-AMP ligase/ S-dih... 47 4e-04
UniRef50_A4FFC7 Cluster: Putative fatty-acid--CoA ligase; n=1; S... 47 4e-04
UniRef50_A0QZD4 Cluster: Acetyl-coenzyme A synthetase; n=3; Cory... 47 4e-04
UniRef50_UPI000038CCA4 Cluster: COG0318: Acyl-CoA synthetases (A... 47 6e-04
UniRef50_Q2BI30 Cluster: Acetyl-coenzyme A synthetase; n=1; Nept... 47 6e-04
UniRef50_Q28MM6 Cluster: AMP-dependent synthetase and ligase; n=... 47 6e-04
UniRef50_A0LVM6 Cluster: Acetoacetyl-CoA synthase; n=5; Bacteria... 47 6e-04
UniRef50_Q0WQ54 Cluster: Acetyl-CoA synthetase-like protein; n=1... 47 6e-04
UniRef50_A0V7F5 Cluster: AMP-dependent synthetase and ligase; n=... 46 8e-04
UniRef50_Q9RLP6 Cluster: Peptide synthetase; n=18; cellular orga... 46 0.001
UniRef50_Q9LCU0 Cluster: PstD; n=2; Mycobacterium avium|Rep: Pst... 46 0.001
UniRef50_Q939Z1 Cluster: Peptide synthetase; n=7; Actinomycetale... 46 0.001
UniRef50_A3PSP1 Cluster: AMP-dependent synthetase and ligase; n=... 46 0.001
UniRef50_A3P7D6 Cluster: Non-ribosomal peptide synthase; n=34; B... 46 0.001
UniRef50_Q55RP2 Cluster: Putative uncharacterized protein; n=2; ... 46 0.001
UniRef50_Q53005 Cluster: 4-hydroxybenzoate: coenzyme A ligase; n... 46 0.001
UniRef50_Q3M5Z4 Cluster: AMP-dependent synthetase and ligase; n=... 46 0.001
UniRef50_O34613 Cluster: YtcI; n=53; Bacillales|Rep: YtcI - Baci... 46 0.001
UniRef50_Q24N89 Cluster: Putative uncharacterized protein; n=1; ... 46 0.001
UniRef50_Q21E99 Cluster: Amino acid adenylation; n=2; Bacteria|R... 46 0.001
UniRef50_Q1V1I6 Cluster: Acetoacetyl-CoA synthase; n=2; Bacteria... 46 0.001
UniRef50_A6V8H5 Cluster: Long-chain-fatty-acid--CoA ligase, puta... 46 0.001
UniRef50_A4TVS6 Cluster: AMP-dependent synthetase and ligase; n=... 46 0.001
UniRef50_A0K0Y8 Cluster: AMP-dependent synthetase and ligase; n=... 46 0.001
UniRef50_A7SU89 Cluster: Predicted protein; n=1; Nematostella ve... 46 0.001
UniRef50_Q62F86 Cluster: AMP-binding domain protein; n=14; Burkh... 45 0.002
UniRef50_Q8RNW9 Cluster: Adenylate-forming enzyme; n=2; Streptom... 45 0.002
UniRef50_Q3WHP4 Cluster: AMP-dependent synthetase and ligase; n=... 45 0.002
UniRef50_Q140M1 Cluster: Putative long chain fatty acid CoA liga... 45 0.002
UniRef50_A6GK66 Cluster: Non-ribosomal peptide synthetase; n=1; ... 45 0.002
UniRef50_A4PHL4 Cluster: Non ribosomal peptide synthetase for vi... 45 0.002
UniRef50_A3RXA3 Cluster: AMP-(Fatty)acid ligases; n=6; Burkholde... 45 0.002
UniRef50_A1RCH2 Cluster: Putative coenzyme A ligase; n=1; Arthro... 45 0.002
UniRef50_Q5TF43 Cluster: Acyl-CoA synthetase short-chain family ... 45 0.002
UniRef50_Q9HEI8 Cluster: Related to acetoacetyl-CoA synthetase; ... 45 0.002
UniRef50_Q8YTR4 Cluster: All2649 protein; n=3; Nostocaceae|Rep: ... 45 0.002
UniRef50_Q62C03 Cluster: Nonribosomal peptide synthetase DhbF; n... 45 0.002
UniRef50_Q5P655 Cluster: Cyclohexanecarboxylate-CoA ligase; n=5;... 45 0.002
UniRef50_Q2SFM4 Cluster: Non-ribosomal peptide synthetase module... 45 0.002
UniRef50_Q5DIU0 Cluster: PvdI; n=3; cellular organisms|Rep: PvdI... 45 0.002
UniRef50_Q13I22 Cluster: Putative AMP-dependent synthetase and l... 45 0.002
UniRef50_Q0X0B9 Cluster: Putative non-ribosomal peptide syntheta... 45 0.002
UniRef50_O68487 Cluster: Actinomycin synthetase II; n=1; Strepto... 45 0.002
UniRef50_A1G2S7 Cluster: Amino acid adenylation domain; n=1; Sal... 45 0.002
UniRef50_Q9M0X9 Cluster: 4-coumarate--CoA ligase-like 7; n=1; Ar... 45 0.002
UniRef50_Q7W4Q6 Cluster: Putative fatty acid CoA ligase; n=3; Bo... 44 0.003
UniRef50_Q5KZX6 Cluster: Hypothetical conserved protein; n=1; Ge... 44 0.003
UniRef50_A6UHL1 Cluster: AMP-dependent synthetase and ligase; n=... 44 0.003
UniRef50_Q4PHX8 Cluster: Putative uncharacterized protein; n=1; ... 44 0.003
UniRef50_Q83MG9 Cluster: Probable crotonobetaine/carnitine-CoA l... 44 0.003
UniRef50_UPI0000165EEF Cluster: acyl-CoA synthase; n=1; Deinococ... 44 0.004
UniRef50_Q9Z4X6 Cluster: CDA peptide synthetase I; n=4; cellular... 44 0.004
UniRef50_Q5P0J2 Cluster: 4-hydroxybenzoate CoA ligase; n=1; Azoa... 44 0.004
UniRef50_Q4ZVI2 Cluster: Amino acid adenylation; n=4; Pseudomona... 44 0.004
UniRef50_Q333V5 Cluster: NRPS protein; n=2; Actinomycetales|Rep:... 44 0.004
UniRef50_Q0SK68 Cluster: Non-ribosomal peptide synthetase; n=1; ... 44 0.004
UniRef50_Q0S5F4 Cluster: Non-ribosomal peptide synthetase; n=1; ... 44 0.004
UniRef50_A5ERA9 Cluster: Arthrofactin synthetase/syringopeptin s... 44 0.004
UniRef50_A5A9U3 Cluster: Mps2 protein; n=2; Mycobacterium|Rep: M... 44 0.004
UniRef50_A4FF93 Cluster: AMP-dependent synthetase and ligase; n=... 44 0.004
UniRef50_A3Z2Q3 Cluster: Acyl-CoA synthase; n=1; Synechococcus s... 44 0.004
UniRef50_A7SNY7 Cluster: Predicted protein; n=1; Nematostella ve... 44 0.004
UniRef50_Q2W0K6 Cluster: Acyl-coenzyme A synthetase/AMP-(Fatty) ... 44 0.005
UniRef50_Q9L8H4 Cluster: Actinomycin synthetase III; n=1; Strept... 44 0.005
UniRef50_Q3L908 Cluster: Putative fatty-acid--CoA ligase; n=1; R... 44 0.005
UniRef50_Q1ITX8 Cluster: AMP-dependent synthetase and ligase; n=... 44 0.005
UniRef50_A7DD68 Cluster: AMP-dependent synthetase and ligase; n=... 44 0.005
UniRef50_A6V359 Cluster: Linear gramicidin synthetase subunit C;... 44 0.005
UniRef50_A6FX12 Cluster: Putative long-chain fatty acid--CoA lig... 44 0.005
UniRef50_A4GHX3 Cluster: AMP-dependent synthetase and ligase; n=... 44 0.005
UniRef50_A3VQJ0 Cluster: Acyl-CoA synthase; n=1; Parvularcula be... 44 0.005
UniRef50_A0Z9R9 Cluster: Putative uncharacterized protein; n=1; ... 44 0.005
UniRef50_A0Z4Z7 Cluster: AMP-dependent synthetase and ligase; n=... 44 0.005
UniRef50_A0QH53 Cluster: Linear gramicidin synthetase subunit D;... 44 0.005
UniRef50_Q97YI1 Cluster: Acetyl-CoA synthetase (Acetate-CoA liga... 44 0.005
UniRef50_Q8YWC0 Cluster: All1695 protein; n=1; Nostoc sp. PCC 71... 43 0.007
UniRef50_Q5KW69 Cluster: Long-chain fatty-acid-CoA ligase; n=1; ... 43 0.007
UniRef50_Q3KF66 Cluster: Amino acid adenylation; n=2; Pseudomona... 43 0.007
UniRef50_Q11F62 Cluster: Amino acid adenylation domain; n=1; Mes... 43 0.007
UniRef50_O07944 Cluster: Pristinamycin I synthase 3 and 4; n=2; ... 43 0.007
UniRef50_A4BLS1 Cluster: Putative non-ribosomal peptide synthase... 43 0.007
UniRef50_Q9C8A3 Cluster: Acetyl-CoA synthetase, putative; 45051-... 43 0.007
UniRef50_Q9A5P7 Cluster: Acid-CoA ligase, putative; n=7; Proteob... 43 0.009
UniRef50_Q7N5R3 Cluster: Complete genome; segment 7/17; n=1; Pho... 43 0.009
UniRef50_Q6D739 Cluster: Non-ribosomal peptide synthetase; n=3; ... 43 0.009
UniRef50_Q6D738 Cluster: Non-ribosomal peptide synthetase; n=3; ... 43 0.009
UniRef50_Q7CT27 Cluster: AGR_L_2309p; n=2; Agrobacterium tumefac... 43 0.009
UniRef50_Q1PUQ3 Cluster: Similar to long chain acyl-coenzyme A s... 43 0.009
UniRef50_A6VYF7 Cluster: Amino acid adenylation domain; n=1; Mar... 43 0.009
UniRef50_A6G5C8 Cluster: Benzoate-CoA ligase family protein; n=1... 43 0.009
UniRef50_A4SX85 Cluster: AMP-dependent synthetase and ligase; n=... 43 0.009
UniRef50_Q0DL03 Cluster: Os05g0132100 protein; n=6; Magnoliophyt... 43 0.009
UniRef50_UPI0000E45C70 Cluster: PREDICTED: hypothetical protein;... 42 0.012
UniRef50_Q8XQ52 Cluster: Putative acyl-coa synthetases(Amp-formi... 42 0.012
UniRef50_Q6MIK4 Cluster: AMP-ligase; n=1; Bdellovibrio bacteriov... 42 0.012
UniRef50_Q3M1P5 Cluster: Amino acid adenylation; n=2; Cyanobacte... 42 0.012
UniRef50_Q6SK65 Cluster: Peptide synthetase; n=5; cellular organ... 42 0.012
UniRef50_Q1D438 Cluster: Non-ribosomal peptide synthase; n=8; Ba... 42 0.012
UniRef50_Q0SEL8 Cluster: Non-ribosomal peptide synthetase; n=1; ... 42 0.012
UniRef50_Q0G336 Cluster: Peptide synthetase; n=1; Fulvimarina pe... 42 0.012
UniRef50_A4KVL6 Cluster: Non-ribosomal peptide synthetase module... 42 0.012
UniRef50_Q4JHB4 Cluster: Acetoacyl-CoA synthetase; n=2; cellular... 42 0.012
UniRef50_Q4J776 Cluster: Acetyl-coenzyme A synthetase; n=2; Sulf... 42 0.012
UniRef50_UPI000038E2BB Cluster: hypothetical protein Faci_030016... 42 0.016
UniRef50_Q7N2F7 Cluster: Complete genome; segment 11/17; n=4; Ph... 42 0.016
UniRef50_Q2JA64 Cluster: Amino acid adenylation; n=3; Actinomyce... 42 0.016
UniRef50_Q10878 Cluster: POSSIBLE FATTY-ACID-CoA LIGASE FADD10; ... 42 0.016
UniRef50_P71716 Cluster: BIFUNCTIONAL ENZYME MBTA: SALICYL-AMP L... 42 0.016
UniRef50_Q8RL48 Cluster: MupU; n=1; Pseudomonas fluorescens|Rep:... 42 0.016
UniRef50_Q13PB0 Cluster: Putative acid-CoA ligase; n=1; Burkhold... 42 0.016
UniRef50_Q0LP24 Cluster: Amino acid adenylation; n=1; Herpetosip... 42 0.016
UniRef50_A6P624 Cluster: Nonribosomal peptide synthetase; n=1; M... 42 0.016
UniRef50_A3KFG6 Cluster: PstD protein; n=1; Actinoplanes friulie... 42 0.016
UniRef50_A0YE26 Cluster: Putative crotonobetaine/carnitine-CoA l... 42 0.016
UniRef50_A0K352 Cluster: AMP-dependent synthetase and ligase; n=... 42 0.016
UniRef50_UPI00006DBBC1 Cluster: COG0365: Acyl-coenzyme A synthet... 42 0.021
UniRef50_Q9PB68 Cluster: Peptide synthase; n=18; Proteobacteria|... 42 0.021
UniRef50_Q7UNY4 Cluster: Peptide synthetase; n=1; Pirellula sp.|... 42 0.021
UniRef50_Q4ZT75 Cluster: Amino acid adenylation; n=2; Pseudomona... 42 0.021
UniRef50_Q4KES9 Cluster: Nonribosomal peptide synthetase; n=6; B... 42 0.021
UniRef50_Q3WCA8 Cluster: AMP-dependent synthetase and ligase; n=... 42 0.021
UniRef50_Q18UZ8 Cluster: AMP-dependent synthetase and ligase; n=... 42 0.021
UniRef50_Q0SKB1 Cluster: Acyl CoA synthetase, AMP-binding protei... 42 0.021
UniRef50_Q0SBN7 Cluster: Probable acid-CoA ligase; n=1; Rhodococ... 42 0.021
UniRef50_Q0K0K4 Cluster: Non-ribosomal peptide synthetase; n=1; ... 42 0.021
UniRef50_A4X2Q7 Cluster: AMP-dependent synthetase and ligase; n=... 42 0.021
UniRef50_A3JR31 Cluster: Putative uncharacterized protein; n=1; ... 42 0.021
UniRef50_A0FXQ3 Cluster: Amino acid adenylation domain; n=2; Bac... 42 0.021
UniRef50_A2Y9K6 Cluster: Putative uncharacterized protein; n=3; ... 42 0.021
UniRef50_A7RFX5 Cluster: Predicted protein; n=1; Nematostella ve... 42 0.021
UniRef50_Q2UH98 Cluster: Acyl-CoA synthetases; n=4; Eurotiomycet... 42 0.021
UniRef50_Q82GQ6 Cluster: Putative cyclohex-1-ene-1-carboxylate:C... 41 0.028
UniRef50_Q7W037 Cluster: Putative coenzyme A ligase; n=4; Bordet... 41 0.028
UniRef50_Q4JSW1 Cluster: Acyl-CoA synthetase; n=1; Corynebacteri... 41 0.028
UniRef50_Q399N2 Cluster: AMP-dependent synthetase and ligase; n=... 41 0.028
UniRef50_Q93N87 Cluster: Peptide synthetase; n=12; Bacteria|Rep:... 41 0.028
UniRef50_Q3DZ13 Cluster: AMP-dependent synthetase and ligase; n=... 41 0.028
UniRef50_Q1IBI9 Cluster: Putative non-ribosomal peptide syntheta... 41 0.028
UniRef50_Q12IB7 Cluster: Amino acid adenylation; n=1; Shewanella... 41 0.028
UniRef50_O54666 Cluster: RifA; n=4; Actinomycetales|Rep: RifA - ... 41 0.028
UniRef50_A3ZYI7 Cluster: Long-chain fatty-acid-CoA ligase; n=1; ... 41 0.028
UniRef50_A7ECX0 Cluster: Putative uncharacterized protein; n=1; ... 41 0.028
UniRef50_Q97UF6 Cluster: Long-chain-fatty-acid--CoA ligase; n=4;... 41 0.028
UniRef50_UPI0001555F59 Cluster: PREDICTED: hypothetical protein,... 41 0.037
UniRef50_UPI0000E478FD Cluster: PREDICTED: hypothetical protein;... 41 0.037
UniRef50_Q8CJX2 Cluster: CDA peptide synthetase III; n=3; Strept... 41 0.037
UniRef50_Q74E61 Cluster: Long-chain-fatty-acid--CoA ligase, puta... 41 0.037
UniRef50_Q5LKI0 Cluster: Benzoate-coenzyme A ligase; n=33; Bacte... 41 0.037
UniRef50_Q3A444 Cluster: Long-chain acyl-CoA synthetases; n=4; D... 41 0.037
UniRef50_Q8GGQ3 Cluster: Nonribosomal peptide synthetase; n=2; S... 41 0.037
UniRef50_Q84HC5 Cluster: Adenylate ligase; n=3; Actinomycetales|... 41 0.037
UniRef50_Q7B6H0 Cluster: Cyclohex-1-ene-1-carboxylate CoA ligase... 41 0.037
UniRef50_Q3WJL5 Cluster: AMP-dependent synthetase and ligase; n=... 41 0.037
UniRef50_Q1D6A0 Cluster: Non-ribosomal peptide synthetase; n=7; ... 41 0.037
UniRef50_Q18RS6 Cluster: AMP-dependent synthetase and ligase; n=... 41 0.037
UniRef50_Q11E51 Cluster: AMP-dependent synthetase and ligase; n=... 41 0.037
UniRef50_Q0SEC4 Cluster: Possible long-chain-fatty-acid-CoA liga... 41 0.037
UniRef50_Q0RMQ4 Cluster: Putative non-ribosomal peptide syntheta... 41 0.037
UniRef50_A6DB12 Cluster: Acyl-CoA synthase; n=1; Caminibacter me... 41 0.037
UniRef50_A5V315 Cluster: AMP-dependent synthetase and ligase; n=... 41 0.037
UniRef50_A3Q4D1 Cluster: AMP-dependent synthetase and ligase; n=... 41 0.037
UniRef50_A3JMY8 Cluster: Non-ribosomal peptide synthetase; n=4; ... 41 0.037
UniRef50_A3DBZ4 Cluster: AMP-dependent synthetase and ligase; n=... 41 0.037
UniRef50_A0HJN0 Cluster: AMP-dependent synthetase and ligase; n=... 41 0.037
UniRef50_Q7QTM8 Cluster: GLP_0_31804_34101; n=2; Giardia lamblia... 41 0.037
UniRef50_Q9HQN8 Cluster: Long-chain fatty-acid-CoA ligase; n=1; ... 41 0.037
UniRef50_UPI00015B53A6 Cluster: PREDICTED: similar to AMP depend... 40 0.049
UniRef50_Q8XS39 Cluster: Probable non ribosomal peptide syntheta... 40 0.049
UniRef50_Q8CV01 Cluster: 2,3-dihydroxybenzoate-AMP ligase; n=2; ... 40 0.049
UniRef50_Q5L0D6 Cluster: Fatty acid-CoA ligase; n=16; Bacillacea... 40 0.049
UniRef50_Q5E2J5 Cluster: Long-chain-fatty-acid--CoA ligase; n=4;... 40 0.049
UniRef50_Q39MZ8 Cluster: AMP-dependent synthetase and ligase; n=... 40 0.049
UniRef50_Q2JA66 Cluster: Amino acid adenylation; n=15; Bacteria|... 40 0.049
UniRef50_Q2XNF8 Cluster: Nonribosomal peptide synthetase-polyket... 40 0.049
UniRef50_Q2PC83 Cluster: Putative polyketide synthase; n=2; Acti... 40 0.049
UniRef50_Q1RPI4 Cluster: 2,3-dihydroxybenzoate-AMP ligase; n=31;... 40 0.049
UniRef50_Q1GM48 Cluster: Acetoacetyl-CoA synthase; n=3; Proteoba... 40 0.049
UniRef50_Q1D5W2 Cluster: Non-ribosomal peptide synthetase/polyke... 40 0.049
UniRef50_Q1ATG8 Cluster: AMP-dependent synthetase and ligase; n=... 40 0.049
UniRef50_Q13G91 Cluster: Putative AMP-dependent synthetase and l... 40 0.049
UniRef50_Q0YRD8 Cluster: Amino acid adenylation; n=2; cellular o... 40 0.049
UniRef50_Q091C0 Cluster: Non-ribosomal peptide synthase; n=2; Cy... 40 0.049
UniRef50_A7BC57 Cluster: Putative uncharacterized protein; n=1; ... 40 0.049
UniRef50_A5V009 Cluster: AMP-dependent synthetase and ligase; n=... 40 0.049
UniRef50_A5UZF0 Cluster: AMP-dependent synthetase and ligase; n=... 40 0.049
UniRef50_A4F5C4 Cluster: AuaE protein; n=1; Stigmatella aurantia... 40 0.049
UniRef50_A1GFR6 Cluster: AMP-dependent synthetase and ligase; n=... 40 0.049
UniRef50_A1G2R8 Cluster: Amino acid adenylation domain; n=1; Sal... 40 0.049
UniRef50_A0UUS2 Cluster: Amino acid adenylation domain; n=5; roo... 40 0.049
UniRef50_A0QHN3 Cluster: Syringomycin synthetase; n=3; Mycobacte... 40 0.049
UniRef50_Q0CFH7 Cluster: Putative uncharacterized protein; n=1; ... 40 0.049
UniRef50_O28423 Cluster: 2,3-dihydrosybenzoate-AMP ligase; n=1; ... 40 0.049
UniRef50_UPI00005F9362 Cluster: COG1021: Peptide arylation enzym... 40 0.065
UniRef50_UPI00003932EB Cluster: COG1022: Long-chain acyl-CoA syn... 40 0.065
UniRef50_Q8G488 Cluster: Possible long-chain-fatty acid CoA liga... 40 0.065
UniRef50_Q5YPH6 Cluster: Putative non-ribosomal peptide syntheta... 40 0.065
UniRef50_Q47NS0 Cluster: Amino acid adenylation; n=1; Thermobifi... 40 0.065
UniRef50_Q2T5X7 Cluster: Peptide synthetase, putative; n=9; Burk... 40 0.065
UniRef50_Q7CRI7 Cluster: AGR_L_3476p; n=2; Agrobacterium tumefac... 40 0.065
UniRef50_Q6J677 Cluster: Acyl-CoA synthetase; n=1; Collimonas fu... 40 0.065
UniRef50_Q2B979 Cluster: Putative long-chain fatty-acid-CoA liga... 40 0.065
UniRef50_Q1ZF62 Cluster: AMP-binding enzyme family protein; n=1;... 40 0.065
UniRef50_Q1IA18 Cluster: Putative non-ribosomal peptide syntheta... 40 0.065
UniRef50_Q1GWS9 Cluster: AMP-dependent synthetase and ligase; n=... 40 0.065
UniRef50_Q0LLQ8 Cluster: Amino acid adenylation; n=2; Herpetosip... 40 0.065
UniRef50_A7HAV7 Cluster: AMP-dependent synthetase and ligase; n=... 40 0.065
UniRef50_A7CNS3 Cluster: AMP-dependent synthetase and ligase; n=... 40 0.065
UniRef50_A6W8M8 Cluster: AMP-dependent synthetase and ligase; n=... 40 0.065
UniRef50_A6V024 Cluster: Amino acid adenylation domain; n=1; Pse... 40 0.065
UniRef50_A6CKR2 Cluster: Long-chain fatty-acid-CoA ligase; n=1; ... 40 0.065
UniRef50_A3PXA5 Cluster: AMP-dependent synthetase and ligase; n=... 40 0.065
UniRef50_A0ACQ7 Cluster: Putative peptide synthetase; n=1; Strep... 40 0.065
UniRef50_A2WTT6 Cluster: Putative uncharacterized protein; n=1; ... 40 0.065
UniRef50_Q7SI43 Cluster: Putative uncharacterized protein NCU006... 40 0.065
UniRef50_Q97WS5 Cluster: Acetyl-CoA synthetase; n=4; Sulfolobus|... 40 0.065
UniRef50_O29418 Cluster: Long-chain-fatty-acid--CoA ligase; n=4;... 40 0.065
UniRef50_UPI0001556387 Cluster: PREDICTED: similar to acyl-CoA s... 40 0.086
UniRef50_Q89L37 Cluster: Fatty acid CoA ligase; n=15; Proteobact... 40 0.086
UniRef50_Q7NXZ0 Cluster: Enterobactin synthetase component F; n=... 40 0.086
UniRef50_Q4ZT67 Cluster: Amino acid adenylation; n=15; Bacteria|... 40 0.086
UniRef50_Q8GGR4 Cluster: Nonribosomal peptide synthetase; n=1; S... 40 0.086
UniRef50_Q0ASY3 Cluster: AMP-dependent synthetase and ligase; n=... 40 0.086
UniRef50_P95819 Cluster: Pristinamycin I synthetase I; n=8; Bact... 40 0.086
UniRef50_A6FC19 Cluster: Acyl-CoA synthase; n=1; Moritella sp. P... 40 0.086
UniRef50_A5G412 Cluster: Amino acid adenylation domain; n=3; Del... 40 0.086
UniRef50_A4JPB0 Cluster: Amino acid adenylation domain; n=1; Bur... 40 0.086
UniRef50_A3VRX0 Cluster: Acetoacetyl-CoA synthase; n=1; Parvular... 40 0.086
UniRef50_A3U1D1 Cluster: AMP-binding enzyme family protein; n=1;... 40 0.086
UniRef50_A3P7D5 Cluster: Non-ribosomal peptide synthase; n=21; B... 40 0.086
UniRef50_A3INW7 Cluster: Amino acid adenylation; n=1; Cyanothece... 40 0.086
UniRef50_A1SPQ8 Cluster: AMP-dependent synthetase and ligase; n=... 40 0.086
UniRef50_A7SE80 Cluster: Predicted protein; n=1; Nematostella ve... 40 0.086
UniRef50_A0JJU1 Cluster: Tenellin polyketide synthase; n=3; Asco... 40 0.086
UniRef50_Q9LU36 Cluster: 4-coumarate--CoA ligase 4; n=192; Sperm... 40 0.086
UniRef50_Q8NTA7 Cluster: Acyl-CoA synthetases (AMP-forming)/AMP-... 39 0.11
UniRef50_Q7NQT6 Cluster: Probable long chain fatty-acid CoA liga... 39 0.11
UniRef50_Q5YPH7 Cluster: Putative non-ribosomal peptide syntheta... 39 0.11
UniRef50_Q5LQF1 Cluster: AMP-binding enzyme; n=1; Silicibacter p... 39 0.11
UniRef50_Q47YU9 Cluster: Acid-CoA ligase family protein; n=1; Co... 39 0.11
UniRef50_Q83Z53 Cluster: Putisolvin synthetase; n=3; Bacteria|Re... 39 0.11
UniRef50_Q21PV0 Cluster: Bifunctional acetoacetyl-CoA synthase/A... 39 0.11
UniRef50_Q0S1Z9 Cluster: Non-ribosomal peptide synthetase; n=1; ... 39 0.11
UniRef50_Q0G5H5 Cluster: Acyl-CoA synthase; n=1; Fulvimarina pel... 39 0.11
UniRef50_Q0UDN6 Cluster: Putative uncharacterized protein; n=1; ... 39 0.11
UniRef50_A5CFR5 Cluster: Acyl-CoA synthetase; n=1; uncultured ma... 39 0.15
UniRef50_Q9KBC2 Cluster: Long-chain acyl-CoA synthetase; n=2; Ba... 39 0.15
UniRef50_Q93H70 Cluster: Non-ribosomal peptide synthetase; n=1; ... 39 0.15
UniRef50_Q93H04 Cluster: Non-ribosomal peptide synthetase; n=1; ... 39 0.15
UniRef50_Q7NDN7 Cluster: Glr4198 protein; n=1; Gloeobacter viola... 39 0.15
UniRef50_Q5QL50 Cluster: Long-chain fatty-acid-CoA ligase; n=15;... 39 0.15
UniRef50_Q5LVC4 Cluster: Long-chain-fatty-acid--CoA ligase, puta... 39 0.15
UniRef50_Q9FB27 Cluster: Peptide synthetase NRPS9-8; n=2; Actino... 39 0.15
UniRef50_Q211M6 Cluster: Amino acid adenylation; n=1; Rhodopseud... 39 0.15
UniRef50_Q1AV60 Cluster: Benzoate-CoA ligase family; n=3; Bacter... 39 0.15
UniRef50_Q120C7 Cluster: AMP-dependent synthetase and ligase; n=... 39 0.15
UniRef50_Q0RF46 Cluster: Putative long-chain-fatty-acid-CoA liga... 39 0.15
UniRef50_Q0FLF0 Cluster: Acetyl-CoA synthetase; n=1; Roseovarius... 39 0.15
UniRef50_Q0B1F7 Cluster: Amino acid adenylation domain; n=2; Bac... 39 0.15
UniRef50_A4PHM3 Cluster: Hybrid non ribosomal peptide synthetase... 39 0.15
UniRef50_A4BRH6 Cluster: Amino acid adenylation; n=1; Nitrococcu... 39 0.15
UniRef50_A3TZL9 Cluster: Putative acid--CoA ligase; n=1; Oceanic... 39 0.15
UniRef50_A3Q3Y3 Cluster: AMP-dependent synthetase and ligase; n=... 39 0.15
UniRef50_A3P7D7 Cluster: Syringomycin synthetase; n=37; Burkhold... 39 0.15
UniRef50_A1W4Z0 Cluster: AMP-dependent synthetase and ligase; n=... 39 0.15
UniRef50_A5C4N6 Cluster: Putative uncharacterized protein; n=1; ... 39 0.15
UniRef50_Q96V34 Cluster: Lysergyl peptide synthetase 1; n=8; Cla... 39 0.15
UniRef50_Q0V4F9 Cluster: Putative uncharacterized protein; n=1; ... 39 0.15
UniRef50_A6S429 Cluster: Putative uncharacterized protein; n=1; ... 39 0.15
UniRef50_A1DJB5 Cluster: Hybrid NRPS/PKS enzyme, putative; n=2; ... 39 0.15
UniRef50_Q08787 Cluster: Surfactin synthetase subunit 3; n=9; Ba... 39 0.15
UniRef50_Q62C88 Cluster: Thiotemplate mechanism natural product ... 38 0.20
UniRef50_Q3A567 Cluster: Acyl-CoA synthetase (AMP-forming)/AMP-a... 38 0.20
UniRef50_Q39TG8 Cluster: AMP-dependent synthetase and ligase; n=... 38 0.20
UniRef50_Q39NV7 Cluster: AMP-dependent synthetase and ligase; n=... 38 0.20
UniRef50_Q2T5W7 Cluster: Nonribosomal peptide synthetase, putati... 38 0.20
UniRef50_Q2LXW4 Cluster: 2,3-dihydroxybenzoate-AMP ligase; n=1; ... 38 0.20
UniRef50_Q8KR71 Cluster: Nonribosomal peptide synthetase PhbF; n... 38 0.20
UniRef50_Q1AT30 Cluster: AMP-dependent synthetase and ligase; n=... 38 0.20
UniRef50_Q12D64 Cluster: AMP-dependent synthetase and ligase; n=... 38 0.20
UniRef50_Q0S7M5 Cluster: AMP-binding CoA ligase; n=1; Rhodococcu... 38 0.20
UniRef50_O30479 Cluster: PKS module 1; n=2; Streptomyces hygrosc... 38 0.20
UniRef50_A7HRW8 Cluster: AMP-dependent synthetase and ligase; n=... 38 0.20
UniRef50_A6UN01 Cluster: Amino acid adenylation domain; n=1; Sin... 38 0.20
UniRef50_A6UN00 Cluster: Amino acid adenylation domain; n=1; Sin... 38 0.20
UniRef50_A5UV23 Cluster: AMP-dependent synthetase and ligase; n=... 38 0.20
UniRef50_A2U676 Cluster: AMP-dependent synthetase and ligase; n=... 38 0.20
UniRef50_A1IEA5 Cluster: AMP-dependent synthetase and ligase; n=... 38 0.20
UniRef50_A0Z1N4 Cluster: Probable acid-CoA ligase; n=1; marine g... 38 0.20
UniRef50_A0Z1E2 Cluster: Acetyl-coenzyme A synthetase; n=1; mari... 38 0.20
UniRef50_A0YE98 Cluster: AMP-dependent synthetase and ligase; n=... 38 0.20
UniRef50_A0V818 Cluster: AMP-dependent synthetase and ligase; n=... 38 0.20
UniRef50_O45873 Cluster: Mechanosensory abnormality protein 18; ... 38 0.20
UniRef50_Q8ZXA2 Cluster: Long-chain-fatty-acid--CoA ligase; n=5;... 38 0.20
UniRef50_UPI00003C8454 Cluster: hypothetical protein Faci_030002... 38 0.26
UniRef50_UPI000023F702 Cluster: hypothetical protein FG10544.1; ... 38 0.26
UniRef50_Q9RYK3 Cluster: Long-chain fatty acid--CoA ligase; n=9;... 38 0.26
UniRef50_Q989U0 Cluster: Mlr6282 protein; n=1; Mesorhizobium lot... 38 0.26
UniRef50_Q8PKR7 Cluster: ATP-dependent serine activating enzyme;... 38 0.26
UniRef50_Q8KGC2 Cluster: Long-chain-fatty-acid--CoA ligase; n=8;... 38 0.26
UniRef50_Q5L252 Cluster: AMP-binding enzyme; n=3; Bacillaceae|Re... 38 0.26
UniRef50_Q5KY15 Cluster: Long-chain fatty-acid-CoA ligase; n=1; ... 38 0.26
UniRef50_Q3KE51 Cluster: Amino acid adenylation; n=7; Pseudomona... 38 0.26
UniRef50_Q9F5J4 Cluster: SimH; n=5; Streptomyces|Rep: SimH - Str... 38 0.26
UniRef50_Q0S6F3 Cluster: Non-ribosomal peptide synthetase; n=2; ... 38 0.26
UniRef50_Q0LP29 Cluster: Amino acid adenylation; n=1; Herpetosip... 38 0.26
UniRef50_O52507 Cluster: Serrawettin synthase; n=1; Serratia liq... 38 0.26
UniRef50_A5V8K9 Cluster: AMP-dependent synthetase and ligase; n=... 38 0.26
UniRef50_A0YEI6 Cluster: AMP-dependent synthetase and ligase; n=... 38 0.26
UniRef50_A6R8A7 Cluster: Predicted protein; n=1; Ajellomyces cap... 38 0.26
UniRef50_Q6N4J8 Cluster: Possible McyE polykeitde synthase and p... 38 0.35
UniRef50_Q4KAY7 Cluster: Pyochelin synthetase E; n=1; Pseudomona... 38 0.35
UniRef50_Q46VE0 Cluster: AMP-dependent synthetase and ligase; n=... 38 0.35
UniRef50_Q8KSQ1 Cluster: Peptide synthetase ScpsA; n=1; Saccharo... 38 0.35
UniRef50_Q4C639 Cluster: Amino acid adenylation; n=1; Crocosphae... 38 0.35
UniRef50_Q4C3C3 Cluster: Non-ribosomal peptide synthase:Amino ac... 38 0.35
>UniRef50_UPI00015B60D2 Cluster: PREDICTED: similar to
ENSANGP00000011599; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000011599 - Nasonia
vitripennis
Length = 684
Score = 254 bits (622), Expect = 2e-66
Identities = 110/165 (66%), Positives = 139/165 (84%)
Frame = +1
Query: 256 YEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHV 435
YE+A ++S+ +PE FW E+G +EW++PWDRVLD+SN PFTKW+VGGE + CYNAVDRHV
Sbjct: 51 YEEAFRKSIENPEEFWAEIGQCIEWSRPWDRVLDNSNEPFTKWYVGGETNACYNAVDRHV 110
Query: 436 VNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEA 615
G G + AL+HDSP+T+TVR++SY EL D+ SRLAG L LGVS+G RVLIYMPL+PE
Sbjct: 111 AAGLGSKTALIHDSPMTETVRRVSYAELLDRTSRLAGALAELGVSRGDRVLIYMPLIPET 170
Query: 616 IIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXASCGV 750
I+A+LAT R+GA+HSVVFGGFAA+EL TRI+HAEP VI+ ASCG+
Sbjct: 171 IVAILATARLGAVHSVVFGGFAAKELATRIDHAEPKVIVAASCGL 215
>UniRef50_Q9VC92 Cluster: CG6432-PA; n=7; cellular organisms|Rep:
CG6432-PA - Drosophila melanogaster (Fruit fly)
Length = 674
Score = 230 bits (563), Expect = 2e-59
Identities = 101/167 (60%), Positives = 132/167 (79%)
Frame = +1
Query: 250 PEYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDR 429
P Y KA ++S+ +P FW E G+ L+W +PW++VLD+SN PFTKW+VGG ++ CYN++DR
Sbjct: 26 PLYLKAYRQSVQNPAAFWEEQGNLLDWDRPWEKVLDNSNPPFTKWYVGGYLNACYNSIDR 85
Query: 430 HVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVP 609
H++ GRG AL+HDSPLT T+R+++Y EL DQ+ LAG L LGV KG RV+IYMPL+P
Sbjct: 86 HILAGRGSNVALIHDSPLTGTLRRVTYQELYDQIVLLAGGLAKLGVVKGDRVVIYMPLIP 145
Query: 610 EAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXASCGV 750
E IIAMLA R+GAIHSVVFGGFAAREL +RIEH EP ++I ++ GV
Sbjct: 146 ETIIAMLAIVRLGAIHSVVFGGFAARELCSRIEHVEPKLVIASNVGV 192
>UniRef50_A7RH51 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 696
Score = 212 bits (517), Expect = 9e-54
Identities = 91/165 (55%), Positives = 126/165 (76%)
Frame = +1
Query: 256 YEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHV 435
Y++A ++S+ DPEGFW +V ++W KP+ +V+D++ PFTKW+ GGE++ C+N +DRH+
Sbjct: 57 YDEAFKQSVEDPEGFWDDVAQGIDWYKPYTKVVDNATPPFTKWFPGGELNTCFNCLDRHI 116
Query: 436 VNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEA 615
NG G + AL++DSP++ + SY L+ V++ AG L +L V KG RV+IYMP+VP+A
Sbjct: 117 ENGIGGRIALIYDSPVSGKIEMYSYQNLQRLVAKFAGALNSLNVGKGDRVVIYMPMVPQA 176
Query: 616 IIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXASCGV 750
+IAMLA RIGAIHSVVFGGFAA EL RIEHAEP VI+ ASCG+
Sbjct: 177 VIAMLACARIGAIHSVVFGGFAAAELARRIEHAEPRVIVTASCGI 221
>UniRef50_UPI0000E4931E Cluster: PREDICTED: hypothetical protein,
partial; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: hypothetical protein, partial -
Strongylocentrotus purpuratus
Length = 353
Score = 202 bits (492), Expect = 1e-50
Identities = 90/169 (53%), Positives = 121/169 (71%)
Frame = +1
Query: 244 TTPEYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAV 423
T Y + S+ PE FW E + W K WDRV+D + +P + W+VGGE+++CYNAV
Sbjct: 56 THSTYPQVFADSITQPEEFWAEQAERVVWFKKWDRVMDLTQSPASNWFVGGELNMCYNAV 115
Query: 424 DRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPL 603
DRHV G G+Q A++HDSP+T +V KI+Y EL+D+VS+ A L GV G RVLIYMP+
Sbjct: 116 DRHVDEGYGDQDAIIHDSPVTGSVTKITYKELQDEVSKFAAALVKSGVKYGDRVLIYMPM 175
Query: 604 VPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXASCGV 750
+P+A++AMLA RIGAIH +VFGGFA++EL RI+H +P VI+ AS GV
Sbjct: 176 IPQAVMAMLACARIGAIHVLVFGGFASKELSVRIDHVKPKVIVSASVGV 224
>UniRef50_Q9H6R3 Cluster: CDNA: FLJ21963 fis, clone HEP05583; n=30;
cellular organisms|Rep: CDNA: FLJ21963 fis, clone
HEP05583 - Homo sapiens (Human)
Length = 686
Score = 200 bits (489), Expect = 2e-50
Identities = 81/170 (47%), Positives = 126/170 (74%)
Frame = +1
Query: 241 GTTPEYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNA 420
G+ EY+ S+ DPE FWG+ ++ W KPW + L++ ++P T+W+V G +++CYNA
Sbjct: 57 GSGSEYKTHFAASVTDPERFWGKAAEQISWYKPWTKTLENKHSPSTRWFVEGMLNICYNA 116
Query: 421 VDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMP 600
VDRH+ NG+G++ A+++DSP+T+T +Y E+ +QVS+LAG L G+ KG V+IYMP
Sbjct: 117 VDRHIENGKGDKIAIIYDSPVTNTKATFTYKEVLEQVSKLAGVLVKHGIKKGDTVVIYMP 176
Query: 601 LVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXASCGV 750
++P+A+ MLA RIGAIHS++FGGFA++EL +RI+H +P V++ AS G+
Sbjct: 177 MIPQAMYTMLACARIGAIHSLIFGGFASKELSSRIDHVKPKVVVTASFGI 226
>UniRef50_O67872 Cluster: Acetyl-coenzyme A synthetase; n=5;
cellular organisms|Rep: Acetyl-coenzyme A synthetase -
Aquifex aeolicus
Length = 510
Score = 168 bits (409), Expect = 1e-40
Identities = 82/163 (50%), Positives = 108/163 (66%)
Frame = +1
Query: 253 EYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRH 432
+YEK + S+ D EGFW +V EL W K WD+VL+ N P+ KW+VG + ++ YN +DRH
Sbjct: 30 DYEKVYEESIKDREGFWAKVAEELHWFKKWDKVLE-WNFPYAKWFVGAKTNITYNCLDRH 88
Query: 433 VVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPE 612
V NG+ + A ++ D +KI+Y EL + V+R+A L +LGV KG RV IYMP E
Sbjct: 89 VQNGKRNKVAYIYVDE-NDNEKKITYGELLELVNRIANGLKSLGVKKGDRVSIYMPTTIE 147
Query: 613 AIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXAS 741
AI MLA RIGAIHSVVF GF+ LRTRIE A+ V++ AS
Sbjct: 148 AIATMLACARIGAIHSVVFAGFSEGALRTRIEDAKAKVVVTAS 190
>UniRef50_P28812 Cluster: Uncharacterized protein PA3568; n=81;
cellular organisms|Rep: Uncharacterized protein PA3568 -
Pseudomonas aeruginosa
Length = 628
Score = 166 bits (404), Expect = 4e-40
Identities = 78/165 (47%), Positives = 108/165 (65%)
Frame = +1
Query: 256 YEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHV 435
Y + RS+ +P FW E L W + +L+ +W+ G ++ Y A+DR +
Sbjct: 3 YLQQHARSIAEPAAFWAEQARSLAWYQAPANILESLPDGTHRWFADGRLNSAYLALDRQI 62
Query: 436 VNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEA 615
GRGEQ AL++DSP+T T + SY L+D+V+RLAG L LGV KG RV+IYMP+VP+A
Sbjct: 63 EEGRGEQTALIYDSPVTGTQDRYSYLRLRDEVARLAGALRALGVGKGDRVIIYMPMVPQA 122
Query: 616 IIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXASCGV 750
+AMLA R+GA+HSVVFGGFA EL RI+ A P +++ ASCG+
Sbjct: 123 AMAMLACARLGAVHSVVFGGFAPYELALRIDDATPKLVLTASCGL 167
>UniRef50_Q871W2 Cluster: Related to acetyl coenzyme A synthetase;
n=9; Pezizomycotina|Rep: Related to acetyl coenzyme A
synthetase - Neurospora crassa
Length = 694
Score = 161 bits (391), Expect = 2e-38
Identities = 78/176 (44%), Positives = 110/176 (62%), Gaps = 8/176 (4%)
Frame = +1
Query: 247 TPEYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFT--------KWWVGGEM 402
T ++AQ SL DPEGFWG +L W + VL + +W+ GE+
Sbjct: 2 THPQDEAQHLSLTDPEGFWGHQAEQLHWHRKPSAVLKRTTKDLKLGTSHSHWEWFPDGEI 61
Query: 403 SVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGAR 582
S CYN +DRHV+ G G+Q A+++DS +T+T ++++Y +L +V AG L GV KG
Sbjct: 62 STCYNCLDRHVLAGHGDQPAILYDSSVTNTKQRLTYKQLLAEVETFAGVLREEGVKKGDV 121
Query: 583 VLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXASCGV 750
VL+YMP+VP +I +LA NR+GAIH+VVFGGFA+ L RIE + P I+ ASCG+
Sbjct: 122 VLVYMPMVPATLIGILAINRLGAIHAVVFGGFASTALAQRIEASRPVAILTASCGI 177
>UniRef50_Q4WAZ5 Cluster: Acetate-CoA ligase, putative; n=1;
Aspergillus fumigatus|Rep: Acetate-CoA ligase, putative
- Aspergillus fumigatus (Sartorya fumigata)
Length = 721
Score = 160 bits (388), Expect = 4e-38
Identities = 75/172 (43%), Positives = 107/172 (62%), Gaps = 8/172 (4%)
Frame = +1
Query: 259 EKAQQRSLNDPEGFWGEVGSELEWTKPWDRVL--------DDSNAPFTKWWVGGEMSVCY 414
++ ++SL +P+ FW L W + D L D + P +W+ GGE+S CY
Sbjct: 8 DEVLRQSLQNPDEFWSRQAERLHWHRKPDTALRTTQKSLPDGTAHPMWEWFPGGEISTCY 67
Query: 415 NAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIY 594
N VDRHV G G + A+ ++SP+T+T I+Y+ L +V LAG L GV KG V++Y
Sbjct: 68 NCVDRHVAAGNGHESAIYYNSPVTNTKETITYHTLLREVETLAGVLRETGVKKGDVVMLY 127
Query: 595 MPLVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXASCGV 750
MP++P A+I MLA NR+GA+HSVVFGGFA L R+E +P V++ ASCG+
Sbjct: 128 MPMIPAALIGMLAVNRLGAVHSVVFGGFAPNALAQRVEACKPDVLLTASCGI 179
>UniRef50_Q5QYS0 Cluster: Propionyl-CoA synthetase; n=1; Idiomarina
loihiensis|Rep: Propionyl-CoA synthetase - Idiomarina
loihiensis
Length = 623
Score = 159 bits (386), Expect = 7e-38
Identities = 77/165 (46%), Positives = 102/165 (61%)
Frame = +1
Query: 256 YEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHV 435
Y+ + DPEGFW E L W K W+ GE+++ Y A+D +
Sbjct: 4 YKNVYSEAQQDPEGFWLEQARRLNWFKTPKVAAQVKKNGLADWFPDGEVNISYLALDAQI 63
Query: 436 VNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEA 615
GRGEQ AL +DSP+T + ++N+L++QV+ A L GV KG RV+IY+P++P+A
Sbjct: 64 EAGRGEQVALYYDSPVTQSKANYTFNQLREQVACFAHVLKQQGVEKGDRVIIYLPMIPQA 123
Query: 616 IIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXASCGV 750
IAMLA RIGAIHSVVFGGFAA EL RI+ A P +II ASCG+
Sbjct: 124 AIAMLACARIGAIHSVVFGGFAAHELAVRIDDAAPKLIITASCGI 168
>UniRef50_Q55404 Cluster: Acetyl-coenzyme A synthetase; n=89;
cellular organisms|Rep: Acetyl-coenzyme A synthetase -
Synechocystis sp. (strain PCC 6803)
Length = 653
Score = 159 bits (385), Expect = 9e-38
Identities = 78/166 (46%), Positives = 110/166 (66%), Gaps = 1/166 (0%)
Frame = +1
Query: 253 EYEKAQQRSLNDPEGFWGEVGS-ELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDR 429
EYE+ R+ ++PE FWGE+ EL W K WD+VLD PF KW+VGG++++ +N +DR
Sbjct: 32 EYEQLYSRAASNPEKFWGELAEQELHWFKKWDQVLD-WQPPFAKWFVGGQLNISHNCLDR 90
Query: 430 HVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVP 609
H+ R + A++ + D+ R I+Y +L +V + A L +LGV KG RV IY+P++P
Sbjct: 91 HLTTWRRNKAAIIWEGEPGDS-RIITYAQLHREVCQFANALKSLGVQKGDRVAIYLPMIP 149
Query: 610 EAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXASCG 747
EA I MLA +RIGA HSVVFGGF+A LR R+ AE ++I A G
Sbjct: 150 EAAITMLACSRIGAPHSVVFGGFSAEALRDRLVDAEAKLVITADGG 195
>UniRef50_P55912 Cluster: Propionate--CoA ligase; n=57;
Bacteria|Rep: Propionate--CoA ligase - Salmonella
typhimurium
Length = 628
Score = 158 bits (384), Expect = 1e-37
Identities = 73/164 (44%), Positives = 108/164 (65%)
Frame = +1
Query: 256 YEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHV 435
+ + QRS+N+PE FW E ++W +P+ + LD S PF +W+ GG ++C+NAVDR
Sbjct: 3 FSEFYQRSINEPEAFWAEQARRIDWRQPFTQTLDHSRPPFARWFCGGTTNLCHNAVDRWR 62
Query: 436 VNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEA 615
+ + E AL+ S TD R ++++L D+V+ +A L +LGV +G RVL+YMP++ EA
Sbjct: 63 -DKQPEALALIAVSSETDEERTFTFSQLHDEVNIVAAMLLSLGVQRGDRVLVYMPMIAEA 121
Query: 616 IIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXASCG 747
I +LA RIGAIHSVVFGGFA+ + RI+ A P +I+ A G
Sbjct: 122 QITLLACARIGAIHSVVFGGFASHSVAARIDDARPALIVSADAG 165
>UniRef50_A2TC85 Cluster: AMP-dependent synthetase and ligase; n=4;
Bacteria|Rep: AMP-dependent synthetase and ligase -
Sphingomonas yanoikuyae
Length = 643
Score = 157 bits (382), Expect = 2e-37
Identities = 73/165 (44%), Positives = 103/165 (62%)
Frame = +1
Query: 256 YEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHV 435
Y+ A + + N P+ FW E ++W + R D S W+ G ++ C+N +DRHV
Sbjct: 10 YDGAVRWAANRPDQFWLEAAKAIDWVENPPRAHDQSMG----WFPEGILNTCHNCLDRHV 65
Query: 436 VNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEA 615
GRG+ AL +DSP+T T+R +Y EL + R A L +LG KG RV++YMP++PE
Sbjct: 66 QAGRGDALALAYDSPVTGTIRHYTYRELLHETERTAAMLASLGAKKGDRVILYMPMIPET 125
Query: 616 IIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXASCGV 750
+ AMLA R+G IHSVVFGGFA EL RI+ A P +++ ASCG+
Sbjct: 126 VFAMLACARLGVIHSVVFGGFAPPELAKRIDDATPKLVLTASCGI 170
>UniRef50_Q82EL5 Cluster: Acetyl-coenzyme A synthetase; n=28;
cellular organisms|Rep: Acetyl-coenzyme A synthetase -
Streptomyces avermitilis
Length = 652
Score = 157 bits (380), Expect = 4e-37
Identities = 83/182 (45%), Positives = 110/182 (60%)
Frame = +1
Query: 202 FVSAADIECYNVCGTTPEYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTK 381
F AD+ N T YE+A+ L GFW E L W LD SN PF K
Sbjct: 16 FAPPADLAA-NANVTAEAYEQAKADRL----GFWAEQARRLTWATEPTETLDWSNPPFAK 70
Query: 382 WWVGGEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTL 561
W+ G+++V YN VDRHV G G++ A+ + D+ R I+Y ELKD+VS+ A LT L
Sbjct: 71 WFKDGKLNVAYNCVDRHVEAGHGDRVAIHFEGEPGDS-RAITYAELKDEVSKAANALTEL 129
Query: 562 GVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXAS 741
GV KG RV +Y+P++PEA++AMLA RIGA HSVVFGGF+A + RI+ A+ ++I A
Sbjct: 130 GVQKGDRVAVYLPMIPEAVVAMLACARIGAAHSVVFGGFSADAIAARIKDADAKLVITAD 189
Query: 742 CG 747
G
Sbjct: 190 GG 191
>UniRef50_A5UUT7 Cluster: Acetate--CoA ligase; n=2; Roseiflexus|Rep:
Acetate--CoA ligase - Roseiflexus sp. RS-1
Length = 639
Score = 155 bits (377), Expect = 8e-37
Identities = 76/162 (46%), Positives = 103/162 (63%)
Frame = +1
Query: 253 EYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRH 432
+YE +RS+ DP+GFW E L W +P+ VLDDS APF KW+VGG+ ++ YNA+DRH
Sbjct: 34 DYEAVYRRSIEDPQGFWAEAAQALHWFEPFHTVLDDSKAPFYKWFVGGKTNMAYNALDRH 93
Query: 433 VVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPE 612
V R + AL+ +S VR +Y +L V++ A L +LGV KG RV IY PE
Sbjct: 94 VQTWRKNKVALIWESE-DGEVRTYTYWQLYRDVNKFANVLKSLGVRKGDRVAIYTGRCPE 152
Query: 613 AIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXA 738
IAMLA RIGA+H+VV+GG + LR+RI+ A V++ A
Sbjct: 153 QAIAMLACARIGAVHTVVYGGLSTEALRSRIDDAHAKVLVVA 194
>UniRef50_A1CSK5 Cluster: Acyl-CoA synthetase, putative; n=7;
Pezizomycotina|Rep: Acyl-CoA synthetase, putative -
Aspergillus clavatus
Length = 716
Score = 152 bits (368), Expect = 1e-35
Identities = 79/166 (47%), Positives = 98/166 (59%), Gaps = 8/166 (4%)
Frame = +1
Query: 277 SLNDPEGFWGEVGSELEWTKPWDRVL--DDSNAP------FTKWWVGGEMSVCYNAVDRH 432
SL DPE FW ++L W KP R L P W+ GE+S YN VDRH
Sbjct: 12 SLQDPESFWSHHTAQLHWHKPPSRALVRQPKTLPSGVTHEHWAWFPDGEISTTYNCVDRH 71
Query: 433 VVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPE 612
V GRG+ A++ DS +T +Y L D+V LAG L GV KG V+IYMP++P
Sbjct: 72 VAAGRGDHAAIIWDSAVTGVQETYTYRRLLDEVEVLAGVLREEGVRKGDVVIIYMPMIPA 131
Query: 613 AIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXASCGV 750
A+IA LA R+GAIHS VFGGFAA+ L RIE A P V++ ASCG+
Sbjct: 132 ALIAALAITRLGAIHSAVFGGFAAKSLAQRIEAARPRVVMTASCGI 177
>UniRef50_A5WC66 Cluster: Propionate--CoA ligase; n=3;
Psychrobacter|Rep: Propionate--CoA ligase -
Psychrobacter sp. PRwf-1
Length = 670
Score = 150 bits (364), Expect = 3e-35
Identities = 87/199 (43%), Positives = 111/199 (55%), Gaps = 27/199 (13%)
Frame = +1
Query: 235 VCGTTPEYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCY 414
V T + + Q SL+DP FWG+ + W KP +VLDDSN PF KW+VGGE ++CY
Sbjct: 9 VTSATESFAELHQNSLSDPNAFWGKQAERIYWHKPPQQVLDDSNLPFAKWFVGGETNLCY 68
Query: 415 NAVDRHVVNGRGEQFA-----------LVHDSP---------------LTDTV-RKISYN 513
N VDRH+ R EQ A L+ + P TD R+++YN
Sbjct: 69 NCVDRHL-EARAEQDAFVWVSSEINQELLDNHPGVAEAFKALDNHVEFYTDYAKRRLTYN 127
Query: 514 ELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAAREL 693
L +V+ A L LGV KG RV+IYMP++ EA AMLA RIGAIHSVVFGGFAA L
Sbjct: 128 RLYKEVNYFADVLQRLGVGKGDRVVIYMPMILEAAYAMLACTRIGAIHSVVFGGFAAHNL 187
Query: 694 RTRIEHAEPTVIIXASCGV 750
R+ AE ++I G+
Sbjct: 188 AVRMSDAEAKLVITVDAGL 206
>UniRef50_Q247U0 Cluster: AMP-binding enzyme family protein; n=1;
Tetrahymena thermophila SB210|Rep: AMP-binding enzyme
family protein - Tetrahymena thermophila SB210
Length = 691
Score = 147 bits (356), Expect = 3e-34
Identities = 74/171 (43%), Positives = 107/171 (62%), Gaps = 5/171 (2%)
Frame = +1
Query: 253 EYEKAQQRSLNDP--EGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVD 426
+Y K S+ + E FW + L W K ++LD S PF +W+ GE+++CYNA+D
Sbjct: 5 QYNKLYNESVQEKSKEQFWQKAAENLHWFKKPSKILDKSQPPFYRWYSDGEINICYNAID 64
Query: 427 RHVVNGRGEQFALVHDSP-LTDTVRK--ISYNELKDQVSRLAGKLTTLGVSKGARVLIYM 597
RH G + AL+ +SP L +V+ +Y +L + V++LA L GV KG RV+IY+
Sbjct: 65 RHQAQ-HGNKTALIWESPSLKSSVQSETYTYKQLYENVAKLAWVLKQFGVKKGDRVIIYL 123
Query: 598 PLVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXASCGV 750
P VPEA+ +MLA +RIGAIH VV+GG+ A+EL RI +P +II AS G+
Sbjct: 124 PNVPEAVFSMLACSRIGAIHVVVYGGYPAKELAGRIIECQPKLIITASAGI 174
>UniRef50_Q22UI3 Cluster: AMP-binding enzyme family protein; n=6;
Oligohymenophorea|Rep: AMP-binding enzyme family protein
- Tetrahymena thermophila SB210
Length = 670
Score = 146 bits (353), Expect = 7e-34
Identities = 80/168 (47%), Positives = 108/168 (64%), Gaps = 4/168 (2%)
Frame = +1
Query: 256 YEKAQQRSLND--PEGFWGEVGSELEWTKPWDRVLDDSNAP--FTKWWVGGEMSVCYNAV 423
Y+ A +RS+N E +W E ++W K D +LD SN F +W+ ++++CYNAV
Sbjct: 35 YQIAFERSVNPLTREDYWREQTHFVDWFKRPDVILDKSNPNPGFWRWFKDSQVNMCYNAV 94
Query: 424 DRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPL 603
DRHV + AL SP R ++ EL+D V+RLAG LGV KG RV+IYMP+
Sbjct: 95 DRHVKQLHDKP-ALHWISPYEKIERTYTWAELQDNVARLAGVYQNLGVKKGDRVVIYMPM 153
Query: 604 VPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXASCG 747
VPEA+ MLA R+GAIHSVVFGGFAA+EL +RI+ +EP +I+ S G
Sbjct: 154 VPEAVFGMLACARLGAIHSVVFGGFAAKELASRIKDSEPALILGGSFG 201
>UniRef50_Q869S4 Cluster: Similar to Bradyrhizobium japonicum.
Acetyl-coenzyme A synthetase; n=2; Dictyostelium
discoideum|Rep: Similar to Bradyrhizobium japonicum.
Acetyl-coenzyme A synthetase - Dictyostelium discoideum
(Slime mold)
Length = 655
Score = 144 bits (350), Expect = 2e-33
Identities = 74/168 (44%), Positives = 109/168 (64%), Gaps = 3/168 (1%)
Frame = +1
Query: 256 YEKAQQRSLNDPEGFWGEVGSE-LEWTKPWDRVLD-DSNAPFTKWWVGGEMSVCYNAVDR 429
YE+ + +L +P FW EV S+ + W K +++V D P +W+ GG ++ CYNA+D
Sbjct: 52 YEQDCEYALKEPIQFWDEVASKYVHWNKRYEKVYSGDEYNP--EWFKGGVLNACYNALDV 109
Query: 430 HVVNG-RGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLV 606
H + + A++H++P + K++Y EL D+V A L LGV KG RV+IYMP++
Sbjct: 110 HAKDPITKNRIAIIHETPSKNNTNKLTYGELWDEVCIFARGLHNLGVEKGDRVVIYMPMI 169
Query: 607 PEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXASCGV 750
+A+IAMLA R+GA HSVVFGGFA+ +L RIEH +P V+I A+ GV
Sbjct: 170 NQALIAMLACARLGATHSVVFGGFASPQLAQRIEHFKPKVVISANFGV 217
>UniRef50_Q0I9W4 Cluster: Acetate--CoA ligase; n=19; cellular
organisms|Rep: Acetate--CoA ligase - Synechococcus sp.
(strain CC9311)
Length = 656
Score = 143 bits (346), Expect = 5e-33
Identities = 72/165 (43%), Positives = 98/165 (59%), Gaps = 1/165 (0%)
Frame = +1
Query: 256 YEKAQQRSLNDPEGFWGEVGS-ELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRH 432
Y + + +DP+ FWG+ EL W +P+ VLD N PF +W+ GG ++ YN +DRH
Sbjct: 35 YRALAEAAKSDPDTFWGDAARRELHWFEPFHTVLDWDNPPFARWFEGGTTNLSYNCLDRH 94
Query: 433 VVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPE 612
+ + + AL+ + D VR +Y EL +V R A L +G+ KG V +YMP+VPE
Sbjct: 95 LNGPKASKTALIWEGEPGD-VRTFTYQELHAEVCRAANALKAIGIGKGDLVALYMPMVPE 153
Query: 613 AIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXASCG 747
A IAMLA RIGA HSVVFGGF+A LR R+ E +I A G
Sbjct: 154 AAIAMLACARIGAPHSVVFGGFSAEALRDRLIDGEVKAVITADGG 198
>UniRef50_Q01L46 Cluster: H0502B11.5 protein; n=5;
Magnoliophyta|Rep: H0502B11.5 protein - Oryza sativa
(Rice)
Length = 747
Score = 142 bits (345), Expect = 6e-33
Identities = 74/184 (40%), Positives = 111/184 (60%), Gaps = 7/184 (3%)
Frame = +1
Query: 211 AADIECYNVCGTTPEYEKAQQRSLNDPEGFWGEVGSELEWTKPW--DRV----LDDSNAP 372
+AD + +T +Y++ +RS++DP GFW E+ W W D V LD + P
Sbjct: 98 SADFASQALVSSTQQYQEMYRRSIDDPAGFWSEIAETFYWKHKWNPDEVCTENLDVTKGP 157
Query: 373 FT-KWWVGGEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGK 549
+W+ GG+ ++CYNAVDR+V G GE+ A+ + K++Y+EL ++V +LA
Sbjct: 158 IKIEWFKGGKTNICYNAVDRNVEAGDGEKIAMYWEGNEPGQDAKLTYSELLNKVCQLANY 217
Query: 550 LTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVI 729
L ++GV KG V+IY+P++ E IAMLA RIGA+HSVVF GF+A L RI +P V+
Sbjct: 218 LKSVGVGKGDAVVIYLPMLMELPIAMLACARIGAVHSVVFAGFSADALAQRIIDCKPKVV 277
Query: 730 IXAS 741
I +
Sbjct: 278 ITCN 281
>UniRef50_O93730 Cluster: Acetyl-coenzyme A synthetase; n=11;
Archaea|Rep: Acetyl-coenzyme A synthetase - Pyrobaculum
aerophilum
Length = 670
Score = 142 bits (343), Expect = 1e-32
Identities = 74/168 (44%), Positives = 104/168 (61%), Gaps = 7/168 (4%)
Frame = +1
Query: 256 YEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHV 435
Y K ++++ + E FW V ELEW KPWD+VLD SN PF KW+VGG +++ Y AVDRHV
Sbjct: 33 YFKFHRQTVENLESFWESVAKELEWFKPWDKVLDASNPPFYKWFVGGRLNLSYLAVDRHV 92
Query: 436 VNGRGEQFAL------VHDSPLTDTVRKISYNELKDQVSRLAGKL-TTLGVSKGARVLIY 594
R + A+ V ++ RK++Y +L +V+R+A L GV KG ++ +Y
Sbjct: 93 KTWRKNKLAIEWEGEPVDENGYPTDRRKLTYYDLYREVNRVAYMLKQNFGVKKGDKITLY 152
Query: 595 MPLVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXA 738
+P+VPE I MLA RIGAI SVVF GF+A L RI ++ ++I A
Sbjct: 153 LPMVPELPITMLAAWRIGAITSVVFSGFSADALAERINDSQSRIVITA 200
>UniRef50_Q8YJ48 Cluster: Acetyl-coenzyme A synthetase; n=48;
cellular organisms|Rep: Acetyl-coenzyme A synthetase -
Brucella melitensis
Length = 651
Score = 140 bits (340), Expect = 3e-32
Identities = 75/169 (44%), Positives = 105/169 (62%), Gaps = 4/169 (2%)
Frame = +1
Query: 256 YEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLD-DSNAPFT-KWWVGGEMSVCYNAVDR 429
Y + + S++DP+GFW + G ++W KP+ +V + D N T KW+ G +V YN +DR
Sbjct: 23 YLEWYEESVSDPDGFWAKHGRRIDWFKPFTKVKNTDFNGDVTIKWYEDGVTNVSYNCIDR 82
Query: 430 HVVNGRGEQFALVH--DSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPL 603
H+ RG++ A++ D+P D +KI+Y EL + V R+A L GV KG RV IY+P+
Sbjct: 83 HL-KSRGDKVAIIWEGDNPYID--KKITYRELYENVCRMANVLKKHGVKKGDRVTIYLPM 139
Query: 604 VPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXASCGV 750
+PEA AMLA RIGA+HSVVF GF+ L RI E T +I A GV
Sbjct: 140 IPEAAYAMLACARIGAVHSVVFAGFSPEALAGRIVDCESTFVITADEGV 188
>UniRef50_Q0JDG8 Cluster: Os04g0404800 protein; n=8; cellular
organisms|Rep: Os04g0404800 protein - Oryza sativa
subsp. japonica (Rice)
Length = 810
Score = 138 bits (334), Expect = 1e-31
Identities = 71/170 (41%), Positives = 105/170 (61%), Gaps = 7/170 (4%)
Frame = +1
Query: 253 EYEKAQQRSLNDPEGFWGEVGSELEWTKPW--DRV----LDDSNAPFT-KWWVGGEMSVC 411
+Y++ +RS++DP GFW E+ W W D V LD + P +W+ GG+ ++C
Sbjct: 220 QYQEMYRRSIDDPAGFWSEIAETFYWKHKWNPDEVCTENLDVTKGPIKIEWFKGGKTNIC 279
Query: 412 YNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLI 591
YNAVDR+V G GE+ A+ + K++Y+EL ++V +LA L ++GV KG V+I
Sbjct: 280 YNAVDRNVEAGDGEKIAMYWEGNEPGQDAKLTYSELLNKVCQLANYLKSVGVGKGDAVVI 339
Query: 592 YMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXAS 741
Y+P++ E IAMLA RIGA+HSVVF GF+A L RI +P V+I +
Sbjct: 340 YLPMLMELPIAMLACARIGAVHSVVFAGFSADALAQRIIDCKPKVVITCN 389
>UniRef50_Q7S7A6 Cluster: Putative uncharacterized protein
NCU01417.1; n=1; Neurospora crassa|Rep: Putative
uncharacterized protein NCU01417.1 - Neurospora crassa
Length = 709
Score = 136 bits (330), Expect = 4e-31
Identities = 77/200 (38%), Positives = 110/200 (55%), Gaps = 32/200 (16%)
Frame = +1
Query: 247 TPEYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFT--------KWWVGGEM 402
T ++AQ SL DPEGFWG +L W + VL + +W+ GE+
Sbjct: 56 THPQDEAQHLSLTDPEGFWGHQAEQLHWHRKPSAVLKRTTKDLKLGTSHSHWEWFPDGEI 115
Query: 403 SVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGAR 582
S CYN +DRHV+ G G+Q A+++DS +T+T ++++Y +L +V AG L GV KG
Sbjct: 116 STCYNCLDRHVLAGHGDQPAILYDSSVTNTKQRLTYKQLLAEVETFAGVLREEGVKKGDV 175
Query: 583 VLIY------------------------MPLVPEAIIAMLATNRIGAIHSVVFGGFAARE 690
VL+Y +P+VP +I +LA NR+GAIH+VVFGGFA+
Sbjct: 176 VLVYSQFTQLRLSRVSTEPATDSLPIYIVPMVPATLIGILAINRLGAIHAVVFGGFASTA 235
Query: 691 LRTRIEHAEPTVIIXASCGV 750
L RIE + P I+ ASCG+
Sbjct: 236 LAQRIEASRPVAILTASCGI 255
>UniRef50_Q89WV5 Cluster: Acetyl-coenzyme A synthetase; n=105;
Bacteria|Rep: Acetyl-coenzyme A synthetase -
Bradyrhizobium japonicum
Length = 648
Score = 136 bits (328), Expect = 7e-31
Identities = 71/169 (42%), Positives = 100/169 (59%), Gaps = 3/169 (1%)
Frame = +1
Query: 253 EYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFT---KWWVGGEMSVCYNAV 423
+Y++ RS++DP GFW E ++W K ++ + S AP KW+ G ++V +N +
Sbjct: 22 KYKEMYARSISDPNGFWAEQAKRIDWMKAPTKIENVSFAPGNVSIKWFEDGVLNVAHNCI 81
Query: 424 DRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPL 603
DRH+ + R Q A++ + R I+Y EL D+V R+A L T V KG RV IY+P+
Sbjct: 82 DRHL-HKRANQTAIIWEGDDPSQSRHITYKELHDEVCRMANILRTRNVKKGDRVTIYLPM 140
Query: 604 VPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXASCGV 750
+PEA AMLA RIGAIHSVVF GF+ L RI + VII A G+
Sbjct: 141 IPEAAYAMLACARIGAIHSVVFAGFSPDSLAQRINDCQSKVIITADEGL 189
>UniRef50_A7ATQ7 Cluster: Acetyl-CoA synthetase, putative; n=1;
Babesia bovis|Rep: Acetyl-CoA synthetase, putative -
Babesia bovis
Length = 703
Score = 134 bits (325), Expect = 2e-30
Identities = 71/162 (43%), Positives = 95/162 (58%), Gaps = 2/162 (1%)
Frame = +1
Query: 253 EYEKAQQRSLNDPEGFWGEVGS-ELEWTKPWDRVLD-DSNAPFTKWWVGGEMSVCYNAVD 426
EY++ +RSL DPEGFWG++ EL W P+ RV + D A W+VGG+++ C N VD
Sbjct: 69 EYKEMHRRSLEDPEGFWGDMAKKELRWIHPFSRVSEGDFTAADYMWFVGGKINACENCVD 128
Query: 427 RHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLV 606
R R A++ + V ++Y EL+ V R A L GV KG V +YMP +
Sbjct: 129 RWAEE-RPNDIAIIAEGDDPTKVTTVTYRELRHNVCRFANVLIDKGVRKGDVVTLYMPSI 187
Query: 607 PEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVII 732
PE AMLA RIGAIHSVVFGG++A + RI A+ +II
Sbjct: 188 PELAYAMLACARIGAIHSVVFGGYSAASIAERIRDADSHIII 229
>UniRef50_Q4J9J7 Cluster: Acetyl-coenzyme A synthetase; n=4;
Sulfolobaceae|Rep: Acetyl-coenzyme A synthetase -
Sulfolobus acidocaldarius
Length = 654
Score = 134 bits (324), Expect = 2e-30
Identities = 64/162 (39%), Positives = 96/162 (59%), Gaps = 1/162 (0%)
Frame = +1
Query: 256 YEKAQQRSLNDPEGFWGEVGSEL-EWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRH 432
Y+ ++S+ +P FW + L +W +PW + TKW+V G+++ YNA+DRH
Sbjct: 23 YKNIYKQSIEEPSKFWDRIAESLIDWFEPWKKTFVQEEGLLTKWFVEGKLNASYNAIDRH 82
Query: 433 VVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPE 612
+ R + A++ +S + R ++Y +L +V+R A L +GV KG RV IYMPL PE
Sbjct: 83 AFSNRKFKAAIIWESGKHER-RVLTYQDLYYEVNRWANALREIGVRKGDRVTIYMPLTPE 141
Query: 613 AIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXA 738
+I+MLA R+GAIH+VVF GF + L RI A V+I A
Sbjct: 142 GVISMLAVTRLGAIHNVVFAGFGVQALADRISDAGSKVVITA 183
>UniRef50_Q8KBY0 Cluster: Acetyl-coenzyme A synthetase; n=44;
cellular organisms|Rep: Acetyl-coenzyme A synthetase -
Chlorobium tepidum
Length = 659
Score = 134 bits (324), Expect = 2e-30
Identities = 62/162 (38%), Positives = 97/162 (59%)
Frame = +1
Query: 253 EYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRH 432
+YEK + DP+ +WG++ + W K WD VL+ NAP+ KW+ GG ++ YN +D H
Sbjct: 41 QYEKLYADAAADPDKYWGDLAEQFHWFKKWDSVLE-WNAPYAKWFNGGTTNIAYNCLDVH 99
Query: 433 VVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPE 612
V + R + A++ + R ++Y EL QVS+ A L G+ G +V IYM +VPE
Sbjct: 100 VGSWRKNKAAIIWEGE-EGNERILTYGELHRQVSKFANVLKIAGIKPGDKVAIYMGMVPE 158
Query: 613 AIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXA 738
+IA+LA R+GA+H+V+F GFAA + R+ + ++I A
Sbjct: 159 LVIAVLACARVGAVHNVIFAGFAAHAITERVNDSRAKIVICA 200
>UniRef50_O25686 Cluster: Acetyl-coenzyme A synthetase; n=40;
Bacteria|Rep: Acetyl-coenzyme A synthetase -
Helicobacter pylori (Campylobacter pylori)
Length = 662
Score = 134 bits (323), Expect = 3e-30
Identities = 66/164 (40%), Positives = 102/164 (62%), Gaps = 2/164 (1%)
Frame = +1
Query: 253 EYEKAQQRSLNDPEGFWGEVGSE-LEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDR 429
EY+ + D E FWG++ + L W KP+D+VL+ NAPF KW+ G+++V YN +DR
Sbjct: 31 EYKDLVHEANEDYEHFWGDLAKQKLTWFKPFDKVLNSDNAPFFKWFENGKINVSYNCIDR 90
Query: 430 HVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTT-LGVSKGARVLIYMPLV 606
H+ + + + A++ + + D I+Y +L +V++ A L V KG RV+IYMP++
Sbjct: 91 HLKDKKNK-VAIIFEGEMGD-YNVITYRKLHSEVNKTANLLKNEFNVKKGDRVIIYMPMI 148
Query: 607 PEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXA 738
E++ MLA RIGAIHS+VF GF+ LR RI A+ ++I A
Sbjct: 149 VESVYMMLACTRIGAIHSIVFAGFSPEALRDRINDAQAKLVITA 192
>UniRef50_Q8EYG2 Cluster: Acetyl-coenzyme A synthetase; n=76;
cellular organisms|Rep: Acetyl-coenzyme A synthetase -
Leptospira interrogans
Length = 661
Score = 133 bits (322), Expect = 4e-30
Identities = 64/166 (38%), Positives = 99/166 (59%), Gaps = 2/166 (1%)
Frame = +1
Query: 256 YEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVL--DDSNAPFTKWWVGGEMSVCYNAVDR 429
Y+ + S+ +P FW + L W K W +VL D NA +W+ GG+++V YN +DR
Sbjct: 31 YKSLYKESIENPNKFWAREANRLIWFKKWTKVLSHDFKNAK-VEWFKGGKLNVSYNCLDR 89
Query: 430 HVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVP 609
H+ + AL+ + R ++Y ++ +V+R A L GV KG RVL+Y+P++P
Sbjct: 90 HISTPLKNKAALIWEGDNPTESRVLTYYDVYREVNRFANILKKFGVKKGDRVLVYLPMIP 149
Query: 610 EAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXASCG 747
E I +LA RIGAIHSVVFGGF+ L++RI+ +P +++ A G
Sbjct: 150 ELAITILACTRIGAIHSVVFGGFSPEALQSRIDDCKPKLVVTADGG 195
>UniRef50_Q9PMD2 Cluster: Acetyl-coenzyme A synthetase; n=143;
cellular organisms|Rep: Acetyl-coenzyme A synthetase -
Campylobacter jejuni
Length = 657
Score = 131 bits (316), Expect = 2e-29
Identities = 69/163 (42%), Positives = 93/163 (57%), Gaps = 1/163 (0%)
Frame = +1
Query: 253 EYEKAQQRSLNDPEGFWGEVGSE-LEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDR 429
EY + D EGFW E +EW P+ RVL++ APF KW+ GG ++V Y +DR
Sbjct: 27 EYYDLCDEAKEDFEGFWKRQAFEKIEWFSPFSRVLNEDKAPFYKWFEGGTLNVSYQCLDR 86
Query: 430 HVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVP 609
H+ R + AL+ + + D +Y L + + A L GV KG RV+IYMP++P
Sbjct: 87 HMKTRRNKA-ALIFEGEMGD-YEVYTYRRLLHETCKAANLLKKFGVKKGDRVVIYMPMIP 144
Query: 610 EAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXA 738
E I MLA RIGAIHSVVFGGF+ LR RI A +++ A
Sbjct: 145 ETAIVMLACARIGAIHSVVFGGFSPEALRDRIIDAGAKLVVTA 187
>UniRef50_P27095 Cluster: Acetyl-coenzyme A synthetase; n=12;
cellular organisms|Rep: Acetyl-coenzyme A synthetase -
Methanothrix soehngenii
Length = 672
Score = 129 bits (311), Expect = 8e-29
Identities = 60/147 (40%), Positives = 91/147 (61%), Gaps = 2/147 (1%)
Frame = +1
Query: 298 FWGEVGSE-LEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRGEQFALVH- 471
FW E+ ++W KP+ +V+DDS P+ W+ GGE+++ YNAVDRH + ++ A +
Sbjct: 64 FWDEMAKTYVDWHKPYTKVMDDSEMPYFHWFTGGEINITYNAVDRHAKGAKKDKVAYIWI 123
Query: 472 DSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGA 651
P V+KI+Y +L +V++ A L +LG+ KG RV IYMP++P+ IAMLA ++G
Sbjct: 124 PEPTDQPVQKITYGDLYKEVNKFANGLKSLGLKKGDRVSIYMPMIPQLPIAMLACAKLGV 183
Query: 652 IHSVVFGGFAARELRTRIEHAEPTVII 732
H VVF GF+++ L R H II
Sbjct: 184 SHIVVFSGFSSKGLMDRAAHCGSRAII 210
>UniRef50_A7HB74 Cluster: AMP-dependent synthetase and ligase; n=8;
cellular organisms|Rep: AMP-dependent synthetase and
ligase - Anaeromyxobacter sp. Fw109-5
Length = 650
Score = 128 bits (310), Expect = 1e-28
Identities = 67/155 (43%), Positives = 93/155 (60%)
Frame = +1
Query: 268 QQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGR 447
+Q + DP+GFW E ++W KP+++V P +W+VGG+++ N +DRHV R
Sbjct: 49 RQFASQDPDGFWREKAKLVDWMKPFEQVTR-FEPPRHEWFVGGKLNATVNCIDRHVFGDR 107
Query: 448 GEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAM 627
+ AL+ + +YN L +V+R A L LGV KG RVL+YMPL PE II+M
Sbjct: 108 RLKAALIWVGEDGEE-HTYTYNRLYREVNRFANALKKLGVRKGDRVLLYMPLTPEGIISM 166
Query: 628 LATNRIGAIHSVVFGGFAARELRTRIEHAEPTVII 732
LA RIGAIHSVVF G + LR+RIE V++
Sbjct: 167 LACARIGAIHSVVFAGMGTQALRSRIEDCAAKVVV 201
>UniRef50_Q8ZV36 Cluster: Acetyl-coenzyme A synthetase; n=4;
Pyrobaculum|Rep: Acetyl-coenzyme A synthetase -
Pyrobaculum aerophilum
Length = 615
Score = 128 bits (310), Expect = 1e-28
Identities = 64/160 (40%), Positives = 98/160 (61%)
Frame = +1
Query: 253 EYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRH 432
+Y + ++S++ PE FW V EL W K W++ LD SN PF +W+VGG ++ YN ++RH
Sbjct: 2 DYIEFWRKSISYPEIFWESVAKELFWKKKWEKPLDGSNPPFYRWFVGGVTNITYNILERH 61
Query: 433 VVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPE 612
+ + + +S L + I+Y EL +V++ A L GV +G RV IYMP++P+
Sbjct: 62 ---SKDKPAIIWFNSELKPHI--ITYGELSQEVNKWACLLKKAGVQQGDRVTIYMPMIPQ 116
Query: 613 AIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVII 732
A AMLA +IGA+H+VVF GF+ R L RI + +I+
Sbjct: 117 AAYAMLAVAKIGAVHNVVFSGFSVRALHERILDSGSKIIL 156
>UniRef50_Q978X5 Cluster: Acetyl-CoA synthetase; n=3; cellular
organisms|Rep: Acetyl-CoA synthetase - Thermoplasma
volcanium
Length = 641
Score = 126 bits (305), Expect = 4e-28
Identities = 59/162 (36%), Positives = 97/162 (59%)
Frame = +1
Query: 253 EYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRH 432
E+++ + S NDP GFW + S+L W K WD V++ P ++ GG ++V N +DRH
Sbjct: 25 EFKRLLEFSKNDPNGFWESIASDLVWRKKWDTVME-GRLPEFSFFKGGYLNVAENLIDRH 83
Query: 433 VVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPE 612
+ G + AL+ +S T +Y L+ V++L+ L +LGV KG RV I++P +PE
Sbjct: 84 IEAGEANRAALIFESE-TGRSAVYTYAMLQSIVNKLSNALRSLGVKKGDRVSIFLPNIPE 142
Query: 613 AIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXA 738
+ ++LA R+GA+ + +F GF+ + L R++H P +II A
Sbjct: 143 TLFSVLACYRVGAVFNTIFSGFSTQALENRLKHFNPMIIITA 184
>UniRef50_Q2RGI0 Cluster: Acetyl-coenzyme A synthetase; n=1;
Moorella thermoacetica ATCC 39073|Rep: Acetyl-coenzyme A
synthetase - Moorella thermoacetica (strain ATCC 39073)
Length = 329
Score = 125 bits (301), Expect = 1e-27
Identities = 63/152 (41%), Positives = 91/152 (59%)
Frame = +1
Query: 292 EGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRGEQFALVH 471
E FWG + L W + WDRVL+ + P W+ GG ++ YN +DRHV R + A++
Sbjct: 43 EEFWGREAARLHWFRRWDRVLE-WDYPLAWWFNGGTLNASYNCLDRHVETWRRNKAAIIW 101
Query: 472 DSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGA 651
+ D V ++Y +L +V++ A L +L V + RV IY+P++PE IAMLA RIGA
Sbjct: 102 EGEPGDAV-VLTYRDLYREVNKFAAVLRSLWVKRDDRVAIYLPMIPELPIAMLACARIGA 160
Query: 652 IHSVVFGGFAARELRTRIEHAEPTVIIXASCG 747
+H+VVFGGF+A LR RI ++I A G
Sbjct: 161 VHNVVFGGFSAAALRDRINDTGAKILITADGG 192
>UniRef50_Q01574 Cluster: Acetyl-coenzyme A synthetase 1; n=40;
Fungi|Rep: Acetyl-coenzyme A synthetase 1 -
Saccharomyces cerevisiae (Baker's yeast)
Length = 713
Score = 125 bits (301), Expect = 1e-27
Identities = 65/168 (38%), Positives = 104/168 (61%), Gaps = 8/168 (4%)
Frame = +1
Query: 253 EYEKAQQRSLNDPEGFWGEVGSE-LEWTKPWDRVL---DDSNAPFTK---WWVGGEMSVC 411
+Y++ + S+ DP F+G ++ L W+KP+D+V + P + W++ G+++ C
Sbjct: 75 DYQRLHKESIEDPAKFFGSKATQFLNWSKPFDKVFIPDPKTGRPSFQNNAWFLNGQLNAC 134
Query: 412 YNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLT-TLGVSKGARVL 588
YN VDRH + ++ A++ + I+Y EL ++V ++A LT ++GV KG V
Sbjct: 135 YNCVDRHALKTPNKK-AIIFEGDEPGQGYSITYKELLEEVCQVAQVLTYSMGVRKGDTVA 193
Query: 589 IYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVII 732
+YMP+VPEAII +LA +RIGAIHSVVF GF++ LR RI + V+I
Sbjct: 194 VYMPMVPEAIITLLAISRIGAIHSVVFAGFSSNSLRDRINDGDSKVVI 241
>UniRef50_Q67QN3 Cluster: Acetyl-coenzyme A synthetase; n=6;
Bacteria|Rep: Acetyl-coenzyme A synthetase -
Symbiobacterium thermophilum
Length = 649
Score = 124 bits (299), Expect = 2e-27
Identities = 68/170 (40%), Positives = 102/170 (60%), Gaps = 3/170 (1%)
Frame = +1
Query: 238 CGTTPEYEKAQQRSLNDPEGFWGEVGSEL--EWTKPWDRVLD-DSNAPFTKWWVGGEMSV 408
CG E+ Q R+ DP FWGE ++ EW +P ++LD + AP+ W+ G M++
Sbjct: 25 CGVG-SLEELQARAAADPAWFWGEAVKDIGIEWYEPPRQILDLSAGAPWAAWFRGARMNL 83
Query: 409 CYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVL 588
+ AVD+H+ N R Q A++++ TVR SY +L + +RLAG L LGV+KG RV
Sbjct: 84 AHEAVDKHLRN-RPHQLAVIYEGE-EGTVRTWSYRQLWAESNRLAGALRALGVAKGDRVG 141
Query: 589 IYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXA 738
I +PL+PEA+ AM+A R+GAI + +F GFA +R+ E ++I A
Sbjct: 142 IMLPLIPEAVAAMMAVARLGAIFTPIFSGFAPAAAASRLADCEAKLLITA 191
>UniRef50_Q01CP6 Cluster: Acyl-CoA synthetase; n=6; Eukaryota|Rep:
Acyl-CoA synthetase - Ostreococcus tauri
Length = 744
Score = 124 bits (299), Expect = 2e-27
Identities = 62/178 (34%), Positives = 99/178 (55%), Gaps = 11/178 (6%)
Frame = +1
Query: 241 GTTPEYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRV----------LDDSNAP-FTKWW 387
G+ +Y RS+ +PE FW E+ EL W +D V D S + KW+
Sbjct: 80 GSMEQYRSMYNRSIKEPEMFWSEIAGELRWETAFDGVDKPEEVLEWNFDPSKGEVYVKWF 139
Query: 388 VGGEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGV 567
GG ++ +N +D + G G+ AL+ ++ R ++NEL+++VS + L G+
Sbjct: 140 AGGRTNMSFNCLDLQIERGLGDSPALIFEANDAVNSRIFTFNELREEVSTFSKFLVAQGI 199
Query: 568 SKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXAS 741
KG RV++Y+P++P IAMLA RIGA+HS+VF G++A+ L R+ + +II AS
Sbjct: 200 GKGDRVIMYLPMIPMMPIAMLACARIGAVHSIVFAGYSAKSLAQRVVDCQAKMIITAS 257
>UniRef50_A6G1J4 Cluster: Acetate--CoA ligase; n=1; Plesiocystis
pacifica SIR-1|Rep: Acetate--CoA ligase - Plesiocystis
pacifica SIR-1
Length = 658
Score = 120 bits (289), Expect = 4e-26
Identities = 65/172 (37%), Positives = 96/172 (55%), Gaps = 6/172 (3%)
Frame = +1
Query: 250 PEYEKAQQRSLNDPEGFW-GEVGSELEWTKPWDRVLDDS-----NAPFTKWWVGGEMSVC 411
P Y + R DP G+W + + W K + L+ + P T W+ GE++V
Sbjct: 30 PAYREHWSRGEADPSGYWLAQTKQRVHWRKAPTQGLEGDCWSVCDGPIT-WFADGELNVT 88
Query: 412 YNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLI 591
+ +DR + RG++ A+V + VR+++Y EL +V R A L LG+ KG R +I
Sbjct: 89 ESCLDRQLAK-RGDKVAIVWEGDEPGDVRELTYKELHAEVCRCANALRELGLKKGERAII 147
Query: 592 YMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXASCG 747
YM +VPEA +AMLA R+GA+HSVVFGGF+A LR R+ +V+I G
Sbjct: 148 YMGMVPEAAVAMLACARLGAVHSVVFGGFSAEALRDRVRDCGASVVITQDVG 199
>UniRef50_Q7RL40 Cluster: Acetate--CoA ligase-related; n=3;
Plasmodium (Vinckeia)|Rep: Acetate--CoA ligase-related -
Plasmodium yoelii yoelii
Length = 951
Score = 119 bits (287), Expect = 7e-26
Identities = 61/168 (36%), Positives = 100/168 (59%), Gaps = 2/168 (1%)
Frame = +1
Query: 253 EYEKAQQRSLNDPEGFWGEVG-SELEWTKPWDRV-LDDSNAPFTKWWVGGEMSVCYNAVD 426
EY+K + S+ +PE FWG++ + L W+K + + + + N W+V G+++ C N VD
Sbjct: 58 EYKKMYEESIKNPELFWGDMAKNNLRWSKLFTKTYIGNFNKGNVSWFVNGKINACDNCVD 117
Query: 427 RHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLV 606
R V + A++ + + +KISY +L ++V ++A L GV K V IY+P++
Sbjct: 118 RWVEK-HPNKTAIIWEKDTPNDYKKISYQKLLEKVCKIANLLKMYGVKKQDCVTIYLPMI 176
Query: 607 PEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXASCGV 750
PE I +MLA RIGAIH+VVF G++ R L RI + T++I + G+
Sbjct: 177 PELIYSMLACARIGAIHNVVFAGYSTRSLSERIVSSGSTILITSDFGL 224
>UniRef50_Q27549 Cluster: Acetyl-coenzyme A synthetase; n=7;
Apicomplexa|Rep: Acetyl-coenzyme A synthetase -
Cryptosporidium parvum
Length = 694
Score = 119 bits (287), Expect = 7e-26
Identities = 65/176 (36%), Positives = 99/176 (56%), Gaps = 3/176 (1%)
Frame = +1
Query: 229 YNVCGTTPEYEKAQQRSLNDPEGFWGEVG-SELEWTKPWDRVLDDSNAPFTK--WWVGGE 399
Y V G +Y++ ++S+ DPEGFW ++ EL W + + +V + W++ G+
Sbjct: 54 YRVDGID-KYKELYEQSIRDPEGFWSQMARKELRWLRDFTKVRSSGTCLQDRLAWFLNGK 112
Query: 400 MSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGA 579
++VC N VDR + AL+ + ++R ISY EL V ++A L G+ KG
Sbjct: 113 LNVCDNCVDRWA-EIQPNTTALIWEGDDPSSIRHISYIELFRNVCKMANVLKRFGIKKGD 171
Query: 580 RVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXASCG 747
V IYMP++PE I MLA RIGA+H VVF GFAA+ L R+ +A +++ A G
Sbjct: 172 SVGIYMPMIPETIYTMLACARIGAVHMVVFAGFAAQNLLERLVNARCKIVVTADQG 227
>UniRef50_A2E702 Cluster: AMP-binding enzyme family protein; n=2;
Trichomonas vaginalis G3|Rep: AMP-binding enzyme family
protein - Trichomonas vaginalis G3
Length = 649
Score = 119 bits (286), Expect = 9e-26
Identities = 58/161 (36%), Positives = 99/161 (61%), Gaps = 2/161 (1%)
Frame = +1
Query: 256 YEKAQQRSLNDPEGFWGEVGSE-LEW-TKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDR 429
Y+K ++ ++ +P FW E + L+W + + ++ + W+ GG+++ CYNAVDR
Sbjct: 11 YKKMEKEAIENPTKFWSETAKDILKWESTDFKNIIGKIGDEKSCWFEGGKINTCYNAVDR 70
Query: 430 HVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVP 609
H + ++ AL+++ D R+++Y EL V ++A L + GV+KG+ V IY P+
Sbjct: 71 HAM-AHPDKVALLYEGNDIDDSRQMTYGELLQNVCKMANVLKSKGVTKGSHVAIYFPVSI 129
Query: 610 EAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVII 732
E I++MLA RIGAIH+V+FG F+ L RI +++ TV+I
Sbjct: 130 EGIVSMLACARIGAIHTVIFGAFSGDALSYRIHNSDATVVI 170
>UniRef50_Q6LEZ6 Cluster: Acetyl-coenzyme a synthetase; n=3;
Plasmodium|Rep: Acetyl-coenzyme a synthetase -
Plasmodium falciparum (isolate 3D7)
Length = 997
Score = 117 bits (282), Expect = 3e-25
Identities = 62/167 (37%), Positives = 97/167 (58%), Gaps = 2/167 (1%)
Frame = +1
Query: 256 YEKAQQRSLNDPEGFWGEVG-SELEWTKPWDRV-LDDSNAPFTKWWVGGEMSVCYNAVDR 429
Y+ + S+N+PE FWG + + L W K + +V L + W+V G+++ C N VDR
Sbjct: 59 YKAMYEESINNPEAFWGNLAKNNLIWYKLFTKVFLGNFKKGNINWFVNGKINACENCVDR 118
Query: 430 HVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVP 609
V + AL+ + D +KI+Y +L ++ ++A L +GV K V IY+P++P
Sbjct: 119 WVEKDPNK-IALIWEQDCPDQYKKITYQKLLEKTCKVANLLKLIGVKKQDTVTIYLPMIP 177
Query: 610 EAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXASCGV 750
E I +MLA RIGAIH+VVF G++A L RI + TV+I + G+
Sbjct: 178 ELIYSMLACVRIGAIHNVVFAGYSAASLSDRIIDSRSTVLITSDFGL 224
>UniRef50_Q9HQU8 Cluster: Acetyl-CoA synthetase; n=11; root|Rep:
Acetyl-CoA synthetase - Halobacterium salinarium
(Halobacterium halobium)
Length = 667
Score = 117 bits (282), Expect = 3e-25
Identities = 59/145 (40%), Positives = 88/145 (60%), Gaps = 1/145 (0%)
Frame = +1
Query: 301 WGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRGEQFALVH-DS 477
W + L+W P+D+VLDDSN PF +W+ GG ++ N +DRH+ + RG++ A+
Sbjct: 49 WTDAADLLDWETPYDQVLDDSNPPFYEWFPGGGLNASANCLDRHL-DERGDEAAIEWVGE 107
Query: 478 PLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIH 657
P + R +Y +L +V+ A L +GV + V +YMP+VPE IAMLA R+GA H
Sbjct: 108 PADEANRTYTYAQLHREVNEFAAGLREMGVGEDDIVTLYMPMVPELPIAMLACARLGAPH 167
Query: 658 SVVFGGFAARELRTRIEHAEPTVII 732
SVVF GF+A L TR+ A+ ++
Sbjct: 168 SVVFAGFSADALSTRMNAADSEYLV 192
>UniRef50_Q75JX6 Cluster: Similar to Vibrio cholerae. PrpE protein;
n=21; Dictyostelium discoideum|Rep: Similar to Vibrio
cholerae. PrpE protein - Dictyostelium discoideum (Slime
mold)
Length = 658
Score = 115 bits (276), Expect = 1e-24
Identities = 60/168 (35%), Positives = 96/168 (57%), Gaps = 2/168 (1%)
Frame = +1
Query: 253 EYEKAQQRSLNDPEGFWGEVGSEL-EWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDR 429
+YE + S +P FW EV + W K +D+V S+ + W+ GGE++ CYN +D+
Sbjct: 9 DYENDCKYSQINPISFWDEVAKKYAHWDKMYDKVYS-SDGMYPDWFKGGELNTCYNVLDK 67
Query: 430 HVVN-GRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLV 606
HV N + +Q AL+++ P K++Y +L ++V + L L +SK VLIYM
Sbjct: 68 HVKNPSKRDQDALIYECPFIKKTIKLTYFQLYEKVCEFSRVLLNLNISKNDNVLIYMANT 127
Query: 607 PEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXASCGV 750
E IIA+L+ RIGA V++ G+ + L RI+ P +II ++CG+
Sbjct: 128 LEPIIALLSCARIGATFIVLYDGYPVKSLIDRIDTFTPKLIITSNCGI 175
>UniRef50_Q81Q80 Cluster: Acetoacetyl-CoA synthase, putative; n=10;
Bacillus|Rep: Acetoacetyl-CoA synthase, putative -
Bacillus anthracis
Length = 646
Score = 113 bits (273), Expect = 3e-24
Identities = 63/166 (37%), Positives = 93/166 (56%), Gaps = 4/166 (2%)
Frame = +1
Query: 253 EYEKAQQRSLNDPEGFWGEVGSEL--EWTKPWDRVLDDSNA-PFTKWWVGGEMSVCYNAV 423
+YE +S+ + FWGE + +W KP+ VLD N PF +W+ GG +V + +
Sbjct: 29 DYETFYNKSIEETAWFWGEAEKVVGYQWMKPYTEVLDLQNGTPFAQWYNGGTCNVVESVL 88
Query: 424 DRHVVNGRGE-QFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMP 600
R + + Q AL ++ T + +Y EL VSR A L G+ KG RV IYMP
Sbjct: 89 SRWLADDETRTQPALQYEGE-NGTSKSFTYEELDSWVSRAANGLKHAGIEKGDRVTIYMP 147
Query: 601 LVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXA 738
++PE ++AMLA +IGAI S +F GFA+ + TR++ A +II A
Sbjct: 148 MIPETVVAMLAVMKIGAIISPIFSGFASDAVMTRVQAAGSKMIITA 193
>UniRef50_Q9NUB1 Cluster: Acetyl-coenzyme A synthetase 2-like,
mitochondrial precursor; n=35; Deuterostomia|Rep:
Acetyl-coenzyme A synthetase 2-like, mitochondrial
precursor - Homo sapiens (Human)
Length = 689
Score = 113 bits (273), Expect = 3e-24
Identities = 63/167 (37%), Positives = 93/167 (55%), Gaps = 2/167 (1%)
Frame = +1
Query: 256 YEKAQQRSLNDPEGFWGEVGSE-LEWTKPWDRVLD-DSNAPFTKWWVGGEMSVCYNAVDR 429
Y ++ +P FWG + + L W P+ V D D + W++GG+++V N +D+
Sbjct: 58 YPALSAQAAREPAAFWGPLARDTLVWDTPYHTVWDCDFSTGKIGWFLGGQLNVSVNCLDQ 117
Query: 430 HVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVP 609
HV E AL+ + T +I+Y EL + RLA L GV +G RV IYMP+ P
Sbjct: 118 HVRKSP-ESVALIWERDEPGTEVRITYRELLETTCRLANTLKRHGVHRGDRVAIYMPVSP 176
Query: 610 EAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXASCGV 750
A+ AMLA RIGA+H+V+F GF+A L RI A+ V+I + G+
Sbjct: 177 LAVAAMLACARIGAVHTVIFAGFSAESLAGRINDAKCKVVITFNQGL 223
>UniRef50_Q5BYW0 Cluster: SJCHGC03435 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC03435 protein - Schistosoma
japonicum (Blood fluke)
Length = 206
Score = 112 bits (270), Expect = 8e-24
Identities = 61/170 (35%), Positives = 101/170 (59%), Gaps = 8/170 (4%)
Frame = +1
Query: 253 EYEKAQQRSLNDPEGFWGEVGSELEWTKP---WDRVL----DDSNAP-FTKWWVGGEMSV 408
E++ ++L++P+ FW + +W KP +++ L D P F KW+ G ++
Sbjct: 21 EHKWLSDKALSNPKEFWLGYAMKFDW-KPHPSFEKCLSYNFDCRMGPIFIKWFEDGYTNI 79
Query: 409 CYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVL 588
CYN +DR++ G G++ A++ + + +++Y+E+ +V R+ L G+ KG V
Sbjct: 80 CYNILDRNIDRGFGDKVAILWEGNDPNDTTQLTYSEMLFKVKRIGKMLENFGIRKGDCVA 139
Query: 589 IYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXA 738
IYMP+VPE I+ MLA RIGA+HSV+FGGF+A L RI A+ ++I A
Sbjct: 140 IYMPMVPELIMTMLACARIGAVHSVIFGGFSACALAGRIMDAKCKILITA 189
>UniRef50_Q4PHQ0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 1162
Score = 112 bits (270), Expect = 8e-24
Identities = 76/199 (38%), Positives = 104/199 (52%), Gaps = 32/199 (16%)
Frame = +1
Query: 250 PEYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVL---DDSNAPFTK-----WWVGGEMS 405
P+ E Q++S+ + + FW + + W KP + NA + W+ +++
Sbjct: 4 PQVE-IQRQSIENRDDFWLKAARSVHWHKPPTVAYGPTSNRNAAYLDPQGQTWFPDAQLN 62
Query: 406 VCYNAVDRHV---------------------VNGRGEQFALVHDSPL---TDTVRKISYN 513
CY+AVDRHV + + A H SPL T R ++Y
Sbjct: 63 TCYSAVDRHVYAPAHAAAAPITVSPDTPHLALAPTAHKVAFHHVSPLSFQTHQSRSVTYY 122
Query: 514 ELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAAREL 693
EL QV +AG L GVSKG V+IYMP+VPE IAMLA RIGA+HSVVFGGFA +EL
Sbjct: 123 ELLQQVQIVAGILRHKGVSKGDAVVIYMPMVPETSIAMLACARIGAVHSVVFGGFAPKEL 182
Query: 694 RTRIEHAEPTVIIXASCGV 750
R+E + +II ASCG+
Sbjct: 183 AKRVEDSRCKIIIAASCGL 201
>UniRef50_Q9NR19 Cluster: Acetyl-coenzyme A synthetase, cytoplasmic;
n=80; Eukaryota|Rep: Acetyl-coenzyme A synthetase,
cytoplasmic - Homo sapiens (Human)
Length = 701
Score = 112 bits (270), Expect = 8e-24
Identities = 58/166 (34%), Positives = 91/166 (54%), Gaps = 7/166 (4%)
Frame = +1
Query: 256 YEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTK------WWVGGEMSVCYN 417
Y + +RS+ +P FWG++ E W P N TK W G ++CYN
Sbjct: 47 YRELHRRSVEEPREFWGDIAKEFYWKTPCPGPFLRYNFDVTKGKIFIEWMKGATTNICYN 106
Query: 418 AVDRHVVNGR-GEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIY 594
+DR+V + G++ A + +I+Y++L QV + + L G+ KG RV IY
Sbjct: 107 VLDRNVHEKKLGDKVAFYWEGNEPGETTQITYHQLLVQVCQFSNVLRKQGIQKGDRVAIY 166
Query: 595 MPLVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVII 732
MP++PE ++AMLA RIGA+HS+VF GF++ L RI + +++I
Sbjct: 167 MPMIPELVVAMLACARIGALHSIVFAGFSSESLCERILDSSCSLLI 212
>UniRef50_Q557A3 Cluster: Putative uncharacterized protein; n=2;
Dictyostelium discoideum|Rep: Putative uncharacterized
protein - Dictyostelium discoideum AX4
Length = 709
Score = 111 bits (266), Expect = 2e-23
Identities = 59/167 (35%), Positives = 91/167 (54%), Gaps = 2/167 (1%)
Frame = +1
Query: 256 YEKAQQRSLNDPEGFWGEVGSE-LEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRH 432
Y+K S N P FW EV + W + +D+V + W+ GGE++ CYN +D H
Sbjct: 10 YDKDFSFSNNQPIEFWDEVAKNFVHWDRMYDKVYSGDEI-YPDWFKGGELNTCYNVLDIH 68
Query: 433 VVN-GRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVP 609
+ N + +Q AL+++ P K++Y +L ++V + L L VSK V+IYM
Sbjct: 69 IKNPAKRDQDALIYECPFLKKTIKLTYYQLYEKVCEFSRALLNLNVSKNDNVIIYMANTV 128
Query: 610 EAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXASCGV 750
EA IAML+ RIGA + +F G++ + L RIE P +II + G+
Sbjct: 129 EAPIAMLSCARIGATYCTLFDGYSVKSLIDRIETITPKLIITTNYGI 175
>UniRef50_Q86AI5 Cluster: Similar to Bradyrhizobium japonicum.
Acetyl-coenzyme A synthetase; n=2; Dictyostelium
discoideum|Rep: Similar to Bradyrhizobium japonicum.
Acetyl-coenzyme A synthetase - Dictyostelium discoideum
(Slime mold)
Length = 606
Score = 110 bits (265), Expect = 3e-23
Identities = 60/167 (35%), Positives = 91/167 (54%), Gaps = 2/167 (1%)
Frame = +1
Query: 256 YEKAQQRSLNDPEGFWGEVGSELE-WTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRH 432
YE + N P FW EV +L W + +D+V + W+ GGE++ CYN +D H
Sbjct: 6 YENEIDLANNRPIEFWDEVAKDLVYWDRMYDKVYSGDEI-YPDWFKGGELNTCYNVLDIH 64
Query: 433 VVNGRG-EQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVP 609
+ N +Q AL+++ P + K++Y + ++V + L L +SK VLIYM
Sbjct: 65 IKNPETRDQTALIYECPFLNKNIKLTYYQFYEKVCEFSRVLLNLNISKNDNVLIYMSNTI 124
Query: 610 EAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXASCGV 750
EA IAML+ RIGA H V+F G++ + L RIE P +II + G+
Sbjct: 125 EAPIAMLSCARIGATHCVLFDGYSVKSLIDRIETITPKLIITTNYGI 171
>UniRef50_Q127M4 Cluster: AMP-dependent synthetase and ligase; n=4;
cellular organisms|Rep: AMP-dependent synthetase and
ligase - Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 688
Score = 109 bits (263), Expect = 5e-23
Identities = 57/149 (38%), Positives = 83/149 (55%), Gaps = 1/149 (0%)
Frame = +1
Query: 289 PEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRGEQFALV 468
PE F E L+W K W+ LD SN PF +W+VGG+++ CYN VDRH+ + +
Sbjct: 63 PECF-KEFADLLDWYKYWETTLDTSNPPFWRWFVGGKINACYNCVDRHLGQHKNKTAIHF 121
Query: 469 HDSPLTDTVRKISYNELKDQVSRLAGKLTTL-GVSKGARVLIYMPLVPEAIIAMLATNRI 645
P + + ++Y EL +V+ A L G+ G RV ++MP+V E I MLA R+
Sbjct: 122 VPEPEDEAPQHLTYQELFVRVNEFAALLRDFCGLKAGDRVTLHMPMVAELPITMLACARL 181
Query: 646 GAIHSVVFGGFAARELRTRIEHAEPTVII 732
G IHS VF GF+ + R+ +E V+I
Sbjct: 182 GVIHSQVFSGFSGKACADRVADSESRVLI 210
>UniRef50_A5K2B0 Cluster: Acetyl-CoA synthetase, putative; n=1;
Plasmodium vivax|Rep: Acetyl-CoA synthetase, putative -
Plasmodium vivax
Length = 1053
Score = 109 bits (261), Expect = 9e-23
Identities = 56/167 (33%), Positives = 96/167 (57%), Gaps = 2/167 (1%)
Frame = +1
Query: 256 YEKAQQRSLNDPEGFWGEVG-SELEWTKPWDRV-LDDSNAPFTKWWVGGEMSVCYNAVDR 429
Y++ + S+N+PE FWG + + + W K + +V + + W+V G+++ C N VDR
Sbjct: 59 YKEMYEESINNPELFWGNIAKNSVRWFKLFTKVYIGNFKKGNISWFVNGKINACDNCVDR 118
Query: 430 HVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVP 609
V + A++ + + +KI+Y +L ++ ++A L GV K V IY+P++P
Sbjct: 119 WVEK-HPNKIAIIWEKDTPNDFKKITYQKLLERTCKIANLLKMYGVKKQDVVTIYLPMIP 177
Query: 610 EAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXASCGV 750
E + MLA RIGAIH+VVF G++A L RI + +V+I + G+
Sbjct: 178 EIVYTMLACARIGAIHNVVFAGYSAGSLCDRILDSNSSVLITSDFGM 224
>UniRef50_UPI0000382F9A Cluster: COG0365: Acyl-coenzyme A
synthetases/AMP-(fatty) acid ligases; n=1;
Magnetospirillum magnetotacticum MS-1|Rep: COG0365:
Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases -
Magnetospirillum magnetotacticum MS-1
Length = 82
Score = 108 bits (260), Expect = 1e-22
Identities = 44/70 (62%), Positives = 56/70 (80%)
Frame = +1
Query: 319 ELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVR 498
E+ W K WD+VLDDS PF +W+VG E + CYNA+DRHV GRG Q A+++DSP+T+T R
Sbjct: 6 EIHWYKTWDKVLDDSKKPFYRWFVGAETNTCYNAIDRHVEQGRGAQTAIIYDSPVTNTKR 65
Query: 499 KISYNELKDQ 528
KISY+ELKDQ
Sbjct: 66 KISYDELKDQ 75
>UniRef50_Q5FTV0 Cluster: Acetyl-coenzyme A synthetase; n=1;
Gluconobacter oxydans|Rep: Acetyl-coenzyme A synthetase
- Gluconobacter oxydans (Gluconobacter suboxydans)
Length = 635
Score = 106 bits (254), Expect = 7e-22
Identities = 61/169 (36%), Positives = 90/169 (53%), Gaps = 1/169 (0%)
Frame = +1
Query: 244 TTPEYEKAQQRSLNDPEGFWGEVGSELEW-TKPWDRVLDDSNAPFTKWWVGGEMSVCYNA 420
T +Y +++ PE +W L W T P ++ W+ GG ++ N
Sbjct: 13 TPADYGHLVEQATVAPEHYWERESRRLNWSTTP-----GQAHCTERGWFPGGVLNASVNC 67
Query: 421 VDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMP 600
+DRH+ RG+Q ALV + TD V +Y L ++V R+A L GV G RV I++P
Sbjct: 68 LDRHLET-RGDQNALVWQAEETDRVVTFTYRTLHERVCRMANVLREQGVQTGDRVAIHLP 126
Query: 601 LVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXASCG 747
VPE +IAMLA RIGAIH V+FGGF+ + R+ + ++I A+ G
Sbjct: 127 SVPEGLIAMLACARIGAIHVVLFGGFSPEAIADRLSDSGAVLVITANMG 175
>UniRef50_Q8SRZ9 Cluster: ACETYLCOENZYME A SYNTHETASE; n=1;
Encephalitozoon cuniculi|Rep: ACETYLCOENZYME A
SYNTHETASE - Encephalitozoon cuniculi
Length = 632
Score = 105 bits (253), Expect = 9e-22
Identities = 53/161 (32%), Positives = 95/161 (59%), Gaps = 1/161 (0%)
Frame = +1
Query: 253 EYEKAQQRSLNDPEGFWGEVGSEL-EWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDR 429
EYE +RS+ D EGFWGE L +W + +DRV ++ + ++W+ GG ++ CYN VDR
Sbjct: 5 EYEGLYKRSIEDKEGFWGEQAKVLLKWDRMFDRVYNN-DFENSRWFEGGMLNACYNCVDR 63
Query: 430 HVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVP 609
H ++ A++++ ++V ++ ++ D+V R+ L G+ KG V +YM + P
Sbjct: 64 HAACSP-DKVAVIYEGNDGESVY-YTFKDVLDEVIRICTILKDEGLEKGDTVAMYMAMSP 121
Query: 610 EAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVII 732
A+ + LA R+G +H+ +FGGF+A + R+ + ++I
Sbjct: 122 YAVFSALACARLGLVHNAIFGGFSASSVALRLNDSNAKLLI 162
>UniRef50_Q55GU6 Cluster: Putative acetyl-CoA synthetase; n=3;
Dictyostelium discoideum|Rep: Putative acetyl-CoA
synthetase - Dictyostelium discoideum AX4
Length = 684
Score = 105 bits (252), Expect = 1e-21
Identities = 57/168 (33%), Positives = 93/168 (55%), Gaps = 2/168 (1%)
Frame = +1
Query: 253 EYEKAQQRSLNDPEGFWGEVGSE-LEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDR 429
+YE S +P FW EV + + W K +D+V + W+ GGE++ CYN +D+
Sbjct: 9 DYENDYSYSQINPISFWDEVAKKFVHWDKIYDKVYSGDEI-YPDWFQGGELNTCYNVLDK 67
Query: 430 HVVNG-RGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLV 606
V N + ++ AL+++ K++Y +L ++V + L + +SK VLIYM
Sbjct: 68 QVKNPLKRDKDALIYECLYLKKTVKLTYYQLYEKVCEFSRVLLNINISKNDNVLIYMANT 127
Query: 607 PEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXASCGV 750
E +IAML+ RIGA +V+F G+ + L RIE PT+II ++ G+
Sbjct: 128 LEPLIAMLSCARIGATFTVLFEGYPVKSLIDRIETITPTLIITSNYGI 175
>UniRef50_Q97WQ9 Cluster: Acetyl-CoA synthetase; n=3;
Sulfolobus|Rep: Acetyl-CoA synthetase - Sulfolobus
solfataricus
Length = 622
Score = 105 bits (252), Expect = 1e-21
Identities = 52/155 (33%), Positives = 91/155 (58%)
Frame = +1
Query: 277 SLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRGEQ 456
S+ +PE FW + + + W + +++L+ P+ KW+VGG +++ YNA+DRH+ + + ++
Sbjct: 18 SMENPEAFWRDKANYVSWFRQPEKILE-GEPPYEKWFVGGTLNISYNAIDRHLPDKK-DK 75
Query: 457 FALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLAT 636
A + D+ R IS+ +L +V++ A L+ LGV KG V + MP +PEA+ LAT
Sbjct: 76 VAFYWTNERLDSFRSISFQDLYQEVNKAAYVLSELGVKKGDTVSMLMPNIPEAVYFSLAT 135
Query: 637 NRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXAS 741
+R+GAI + + G + + R V+I AS
Sbjct: 136 HRLGAILIIHYVGLSEETVAYRFNDCGSKVLIVAS 170
>UniRef50_Q72J94 Cluster: Acetyl-coenzyme A synthetase; n=2; Thermus
thermophilus|Rep: Acetyl-coenzyme A synthetase - Thermus
thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Length = 845
Score = 105 bits (251), Expect = 2e-21
Identities = 59/163 (36%), Positives = 86/163 (52%)
Frame = +1
Query: 250 PEYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDR 429
P+ A + SL DPE FW W +PW V + W+ GG +V NA+DR
Sbjct: 265 PDPRAAHRASLEDPEAFWEGFARGFAWERPWKAVFRREDRT---WFAGGLTNVALNALDR 321
Query: 430 HVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVP 609
H+ + +Q AL+ + K +Y E+++ SRLAG TLGV +G RV +Y+P
Sbjct: 322 HLPE-KAQQVALLTLDG-EGRLGKWTYKEVRELSSRLAGLFRTLGVGRGDRVALYLPTGL 379
Query: 610 EAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXA 738
EA +A LA RIGA+H+ + G LR R+E P +++ A
Sbjct: 380 EAALAALACARIGAVHAALPLGLGPEALRRRLEDLRPRLLVAA 422
>UniRef50_Q54YU1 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 661
Score = 105 bits (251), Expect = 2e-21
Identities = 49/130 (37%), Positives = 79/130 (60%)
Frame = +1
Query: 334 KPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYN 513
K ++ + + +N +W+ GG ++ CYNA+D+H+VNG GE+ A VH+ P +I+Y
Sbjct: 7 KEYENIYNSNN---NEWFSGGLLNACYNALDKHIVNGGGEEIAFVHEIPSKQISTQITYK 63
Query: 514 ELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAAREL 693
+L D+V + + L LG+ KG V+IYM E II+ L+ RIGA H+++FGG+ + L
Sbjct: 64 QLFDKVCKFSRSLKNLGIKKGDIVIIYMHNSIELIISALSCCRIGATHNIIFGGYTQKGL 123
Query: 694 RTRIEHAEPT 723
+ PT
Sbjct: 124 TDLLNIYSPT 133
>UniRef50_Q93LL2 Cluster: Acetyl-coenzyme A synthetase; n=165;
cellular organisms|Rep: Acetyl-coenzyme A synthetase -
Nostoc linckia
Length = 337
Score = 105 bits (251), Expect = 2e-21
Identities = 50/123 (40%), Positives = 80/123 (65%)
Frame = +1
Query: 379 KWWVGGEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTT 558
KW+ G ++V + +DRH+ RG+Q A++ + + K++Y EL +V +LA +
Sbjct: 8 KWFEDGVLNVTESCLDRHLAT-RGDQVAIIWEGDDPNADSKVTYRELHARVCQLANAMRG 66
Query: 559 LGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXA 738
+GV KG RV IY+P++ EA +AMLA RIGA+HS+VFGGF+ L +RI+ ++ ++I A
Sbjct: 67 MGVQKGDRVCIYLPMIEEAAVAMLACARIGAVHSIVFGGFSPDSLSSRIQDSDCVLLITA 126
Query: 739 SCG 747
G
Sbjct: 127 DEG 129
>UniRef50_A1S0M6 Cluster: AMP-dependent synthetase and ligase; n=1;
Thermofilum pendens Hrk 5|Rep: AMP-dependent synthetase
and ligase - Thermofilum pendens (strain Hrk 5)
Length = 588
Score = 104 bits (250), Expect = 2e-21
Identities = 58/162 (35%), Positives = 83/162 (51%)
Frame = +1
Query: 244 TTPEYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAV 423
T EY + + S+ D GFW L W KPW+RV++ AP +W+ GGE+S N V
Sbjct: 20 TLAEYRRVYRESVEDVYGFWSSYARLLLWRKPWERVVE-GEAPRVRWFAGGELSPYENVV 78
Query: 424 DRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPL 603
RH + A++++S D ++Y L R+AG L ++GV +G V +Y P
Sbjct: 79 SRHRGTPVWRKVAVLYESESGDA-EVLTYEGLDALAGRIAGWLESVGVGRGDWVTVYSPP 137
Query: 604 VPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVI 729
PE++ MLA R+GA VF GF EL RI V+
Sbjct: 138 NPESLAFMLAAMRVGAPFEPVFTGFGYYELAKRIARRGSRVV 179
>UniRef50_A4A7V6 Cluster: Acetyl-coenzyme A synthetase/GroES-like
domain; n=4; Bacteria|Rep: Acetyl-coenzyme A
synthetase/GroES-like domain - Congregibacter litoralis
KT71
Length = 1809
Score = 103 bits (248), Expect = 4e-21
Identities = 57/152 (37%), Positives = 82/152 (53%), Gaps = 11/152 (7%)
Frame = +1
Query: 325 EWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRK- 501
EW PW R DDS APF +W+ G + C+N VDRHV+ GRG+ A+V + D R
Sbjct: 75 EWF-PWTRAFDDSRAPFYRWYAGALTNACFNEVDRHVLAGRGDATAIVFEGDRWDPSRND 133
Query: 502 ----------ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGA 651
+S+ +L + A L++LG+ +G R+ +P + E I A R+G
Sbjct: 134 GKGGPVQEITVSFRQLLAETVLRAEVLSSLGLKRGDRIAFNLPNILEQIFYTQAAKRLGI 193
Query: 652 IHSVVFGGFAARELRTRIEHAEPTVIIXASCG 747
I++ VFGGF+A+ L RI A TV+I A G
Sbjct: 194 IYTPVFGGFSAKTLSDRIYDAGATVVITADGG 225
>UniRef50_Q6U666 Cluster: Putative uncharacterized protein; n=1;
Klebsiella pneumoniae|Rep: Putative uncharacterized
protein - Klebsiella pneumoniae
Length = 579
Score = 103 bits (247), Expect = 5e-21
Identities = 55/156 (35%), Positives = 88/156 (56%), Gaps = 3/156 (1%)
Frame = +1
Query: 274 RSLNDP--EGFWGEVGSELEWTKPWDRVLDD-SNAPFTKWWVGGEMSVCYNAVDRHVVNG 444
+S +DP FW E + L W + V++ +P +W+ GG ++ +NA+DRH+
Sbjct: 28 QSEHDPFLRDFWREESARLYWETDFTEVVESLDGSPRCRWFTGGRTNLSFNALDRHLAE- 86
Query: 445 RGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIA 624
+GE+ A++H L T R +SY EL QV+ L + + GV G RVLI +P+ P +A
Sbjct: 87 KGEKCAIIHRDYLGQTHR-LSYRELWQQVNTLCSMMQSWGVKPGDRVLIALPMTPLVAVA 145
Query: 625 MLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVII 732
MLA RIGA+H V++ L RI ++P +++
Sbjct: 146 MLACARIGAVHVVLYSSITHEALMQRIAVSQPVLLL 181
>UniRef50_Q8ZUB3 Cluster: Acetyl-coenzyme A synthetase; n=4;
Archaea|Rep: Acetyl-coenzyme A synthetase - Pyrobaculum
aerophilum
Length = 651
Score = 103 bits (246), Expect = 6e-21
Identities = 61/165 (36%), Positives = 92/165 (55%), Gaps = 6/165 (3%)
Frame = +1
Query: 253 EYEKAQQRSLNDPEGFWGE----VGSELEWTKPWDRVLD-DSNAPFTKWWVGGEMSVCYN 417
+YE R L D +G+W E + W K +++ + + PF KW+VGG + Y+
Sbjct: 7 KYE-VYNRWLQDSDGYWQEFIEKTAGYIYWAKKPEKIFEWNPPNPF-KWFVGGYTNAGYS 64
Query: 418 AVDRHVVNGR-GEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIY 594
AVD + GR G++ A ++ +P R+I+Y EL V R++ L GV KG +L+Y
Sbjct: 65 AVDYKL--GRFGDKTAYIYINPEASVERRITYGELYQLVCRISAALRAFGVKKGDTILVY 122
Query: 595 MPLVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVI 729
MP EA+ +LA RIGA+ S VF GF+ + + RIE EP +I
Sbjct: 123 MPNSIEAVAVLLAAARIGAVSSTVFAGFSPKAVADRIELVEPKII 167
>UniRef50_A4WKF4 Cluster: AMP-dependent synthetase and ligase; n=3;
Pyrobaculum|Rep: AMP-dependent synthetase and ligase -
Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321)
Length = 633
Score = 101 bits (243), Expect = 1e-20
Identities = 57/160 (35%), Positives = 85/160 (53%)
Frame = +1
Query: 253 EYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRH 432
+Y+K + SL PE FW S L W +PW ++++ + P +W+VGGE+S N V +H
Sbjct: 28 QYKKIYKESLK-PE-FWAREASYLIWERPWTKLVE-GDPPAVRWFVGGELSPYKNIVGKH 84
Query: 433 VVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPE 612
++ AL+ ++ +Y++L +R +G L LGV KG V+ Y P PE
Sbjct: 85 AGTWIWDKVALIWRGE-DGLIKTFTYSDLDQLAARYSGALRALGVGKGDWVMFYAPPTPE 143
Query: 613 AIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVII 732
I MLA RIGA VF GF +L RIE P +++
Sbjct: 144 VIALMLAAVRIGAPFEPVFTGFGHGDLAMRIEDRRPELLV 183
>UniRef50_Q9RX55 Cluster: Acetyl-CoA synthase; n=4; cellular
organisms|Rep: Acetyl-CoA synthase - Deinococcus
radiodurans
Length = 642
Score = 100 bits (240), Expect = 3e-20
Identities = 66/161 (40%), Positives = 94/161 (58%), Gaps = 3/161 (1%)
Frame = +1
Query: 259 EKAQQRSLND-PEG-FWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRH 432
E+AQQ L D P G +W V SEL W P L+ + F +++ G + +V N +DRH
Sbjct: 26 ERAQQ--LRDMPAGDYWLSVASELTWDVPPTTALEGTFGDF-QYFPGAKGNVSVNCLDRH 82
Query: 433 VVNGRGEQFALVHDSPLTDTVRKI-SYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVP 609
N + AL ++ D +++ SY +L D +R A L LGV KG RV IY+ VP
Sbjct: 83 PKN----RVALYYERE--DGLKETWSYGDLTDATARFAAALQDLGVDKGDRVAIYLSNVP 136
Query: 610 EAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVII 732
EA IA+ A RIGAI+SV+F GF+A +R R+ A+P V++
Sbjct: 137 EAFIAIHACYRIGAIYSVIFAGFSASAVRDRLTDAQPKVVV 177
>UniRef50_Q9HLJ9 Cluster: Acetyl-CoA synthetase related protein;
n=2; Thermoplasma|Rep: Acetyl-CoA synthetase related
protein - Thermoplasma acidophilum
Length = 619
Score = 100 bits (239), Expect = 4e-20
Identities = 59/159 (37%), Positives = 92/159 (57%), Gaps = 3/159 (1%)
Frame = +1
Query: 274 RSLNDPEGFWGEVGSEL--EWTKPWDRVLDDSNA-PFTKWWVGGEMSVCYNAVDRHVVNG 444
R+ DPE FW V +L E+ K +D V+D S P+ KW+ GG +++ YNAV+R+
Sbjct: 33 RADRDPEWFWPRVIDDLGLEFFKKFDHVMDLSEGVPWAKWFTGGRINIEYNAVERY---S 89
Query: 445 RGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIA 624
E A+V++S K+SY+EL +VS L+ + +G+ +G RV IYMP + IA
Sbjct: 90 DSENTAIVYESE-DGYKSKMSYSELNRKVSALSSAIHDMGIGRGDRVAIYMPFNANSAIA 148
Query: 625 MLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXAS 741
A RIGAI +F G+ +R RIE + +++I ++
Sbjct: 149 FYAVLRIGAIAVPMFSGYGVDAVRNRIEDSGSSLMITSA 187
>UniRef50_Q140P4 Cluster: Putative acetyl-CoA synthetase and ligase;
n=1; Burkholderia xenovorans LB400|Rep: Putative
acetyl-CoA synthetase and ligase - Burkholderia
xenovorans (strain LB400)
Length = 650
Score = 99 bits (238), Expect = 6e-20
Identities = 52/151 (34%), Positives = 86/151 (56%), Gaps = 1/151 (0%)
Frame = +1
Query: 289 PEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGR-GEQFAL 465
P+ +W V + W +PW+ V D N P K++ GG ++VC N VDR+ + + A+
Sbjct: 43 PDAYWEWVAKKFRWMRPWESVRD-GNFPEFKYFAGGMLNVCDNCVDRYAEDPHYASRPAI 101
Query: 466 VHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRI 645
+ D +SY +L+ +R A L +LGV +G V IY+P + E+ +A+ A NRI
Sbjct: 102 TWEGEPGDCAT-LSYAQLRTATARFANGLRSLGVGQGDVVAIYLPNMLESFVAIQACNRI 160
Query: 646 GAIHSVVFGGFAARELRTRIEHAEPTVIIXA 738
GAI++V+F GF+A R++ + V++ A
Sbjct: 161 GAIYTVLFAGFSADAAALRLQTSRAKVLVTA 191
>UniRef50_Q5P1M8 Cluster: Acyl-CoA synthetase; n=2; Azoarcus|Rep:
Acyl-CoA synthetase - Azoarcus sp. (strain EbN1)
(Aromatoleum aromaticum (strain EbN1))
Length = 663
Score = 99.5 bits (237), Expect = 8e-20
Identities = 53/166 (31%), Positives = 90/166 (54%), Gaps = 3/166 (1%)
Frame = +1
Query: 253 EYEKAQQRSLNDPEGFWGEV--GSELEWTKPWDRVLD-DSNAPFTKWWVGGEMSVCYNAV 423
+ + ++R+ +PE FW +V L+W P+ + LD + KW+VGG + + N V
Sbjct: 27 DLDDLRERAAREPERFWDQVLEAIGLDWATPYRQTLDLTDGVMWPKWFVGGRLDLVDNLV 86
Query: 424 DRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPL 603
+H + A+ + + +R +SY L +V R+A L LGVS+G R+ +Y+P+
Sbjct: 87 GKHA-RATPAKIAVRWEGDGGE-LRTLSYAALAGEVERVAAGLRALGVSEGERIALYLPM 144
Query: 604 VPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXAS 741
V EA++ MLA RIGA+ F G+ A + R+ E V++ A+
Sbjct: 145 VAEAVVTMLAATRIGAVFIPFFSGYGADSVAQRVADCEARVLVCAN 190
>UniRef50_Q1JYJ4 Cluster: AMP-dependent synthetase and ligase; n=1;
Desulfuromonas acetoxidans DSM 684|Rep: AMP-dependent
synthetase and ligase - Desulfuromonas acetoxidans DSM
684
Length = 621
Score = 99.1 bits (236), Expect = 1e-19
Identities = 49/137 (35%), Positives = 78/137 (56%)
Frame = +1
Query: 322 LEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRK 501
+EW +P+ +VLD+ P+ +W+ GG+++V +N + RH+ R + AL+ + R
Sbjct: 38 IEWHEPYRKVLDNMAPPYYRWYTGGKLNVYHNILGRHLETERRNKAALIWRGANFEE-RT 96
Query: 502 ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFA 681
+Y L +V + L LGV KG RVL++MP +PE +IAM+A IGAIH ++
Sbjct: 97 YTYQTLAHEVLAMINGLVHLGVKKGDRVLLFMPDIPETVIAMIACASIGAIHVAYHMAYS 156
Query: 682 ARELRTRIEHAEPTVII 732
A L R+ H + II
Sbjct: 157 AEALAQRLNHCQAKFII 173
>UniRef50_Q0FW37 Cluster: Acyl-CoA synthetase; n=1; Roseovarius sp.
HTCC2601|Rep: Acyl-CoA synthetase - Roseovarius sp.
HTCC2601
Length = 656
Score = 98.7 bits (235), Expect = 1e-19
Identities = 50/161 (31%), Positives = 84/161 (52%), Gaps = 3/161 (1%)
Frame = +1
Query: 259 EKAQQRSLNDPEGFWGEVGSEL--EWTKPWDRVLDDSNA-PFTKWWVGGEMSVCYNAVDR 429
E + S++DPE FW +L +T PW DDS F +W+ GG ++V + V R
Sbjct: 40 EDMHRASIDDPESFWPRALDDLGVTFTTPWSTFRDDSAGFAFPRWFSGGALNVATHCVTR 99
Query: 430 HVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVP 609
H + + V + R++S+ L +V R+A L LG+ KG RV +++P++P
Sbjct: 100 HAKDPEAAKRPAVISEADSGVCRELSFGALGAEVERVAAGLAALGIGKGDRVGLFLPVIP 159
Query: 610 EAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVII 732
EA +A++A +IGA+ F G+ L R+ A+ ++
Sbjct: 160 EAAVALMACAKIGAVAVPAFSGYGPDPLAARLNAADAVALV 200
>UniRef50_Q39MW7 Cluster: AMP-dependent synthetase and ligase; n=1;
Burkholderia sp. 383|Rep: AMP-dependent synthetase and
ligase - Burkholderia sp. (strain 383) (Burkholderia
cepacia (strain ATCC 17760/ NCIB 9086 / R18194))
Length = 668
Score = 98.3 bits (234), Expect = 2e-19
Identities = 53/153 (34%), Positives = 87/153 (56%), Gaps = 3/153 (1%)
Frame = +1
Query: 289 PEGFWGEV--GSELEWTKPWDRVLDDSNA-PFTKWWVGGEMSVCYNAVDRHVVNGRGEQF 459
P+ +W + +L + +P+D V+D + + KW VGG + N +DR+ R Q
Sbjct: 52 PDDYWSALIRHMDLRFYQPYDAVVDTRDGIEWAKWCVGGTTNAVLNCLDRYRGTARDRQE 111
Query: 460 ALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATN 639
A+V + TVR+ +Y EL Q SRLA L +G +G + +Y+P+VPEA+ MLA +
Sbjct: 112 AVVWEGE-DGTVRRWTYAELDAQTSRLAAGLREIGCRQGDVIALYLPMVPEAVAGMLAIS 170
Query: 640 RIGAIHSVVFGGFAARELRTRIEHAEPTVIIXA 738
+IGAI +F GF A+ + +R++ A ++ A
Sbjct: 171 KIGAIVLPLFSGFGAQAVASRLQDAGAVAVLTA 203
>UniRef50_Q4QBC0 Cluster: Acetyl-CoA synthetase, putative; n=6;
Eukaryota|Rep: Acetyl-CoA synthetase, putative -
Leishmania major
Length = 705
Score = 98.3 bits (234), Expect = 2e-19
Identities = 55/164 (33%), Positives = 92/164 (56%), Gaps = 10/164 (6%)
Frame = +1
Query: 277 SLNDPEGFWGEVGS-ELEWTKPW--DRVL-----DDSNAP-FTKWWVGGEMSVCYNAVDR 429
S+ + FW E+ + W W D+ + D S P F KW+ G ++CYNA+DR
Sbjct: 70 SIEHNDVFWAEIARRDFYWKTTWPDDQHVKSYNFDKSKGPIFVKWFEGAVTNICYNALDR 129
Query: 430 HVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLT-TLGVSKGARVLIYMPLV 606
H+ + ++ + K++Y + +V LA L G++KG RV +Y+P++
Sbjct: 130 HLPAHK-DRVCFYFEGNDPSVTEKVTYGSMYTRVVELANVLKHQYGITKGDRVGLYLPMI 188
Query: 607 PEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXA 738
P A +AMLA RIGA+ +V+FGGF+A+ L +R++ A+ ++I A
Sbjct: 189 PFAAVAMLACARIGAVITVIFGGFSAQALSSRLKDAQAKLLITA 232
>UniRef50_A7DME3 Cluster: AMP-dependent synthetase and ligase; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep:
AMP-dependent synthetase and ligase - Candidatus
Nitrosopumilus maritimus SCM1
Length = 641
Score = 98.3 bits (234), Expect = 2e-19
Identities = 52/157 (33%), Positives = 93/157 (59%), Gaps = 4/157 (2%)
Frame = +1
Query: 271 QRSLNDPEGFWGEVGSELE--WTKPWDRVLDDSNA-PFTKWWVGGEMSVCYNAVDRHV-V 438
++S ++ E FW EV ++ W P+ ++LD SN +KW+V G+ ++ + V++ V +
Sbjct: 35 KKSKDELEWFWQEVDKDIGVVWDSPYSQILDSSNGIAHSKWFVNGKTNIYKSTVEKFVKL 94
Query: 439 NGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAI 618
+ V + T K++Y EL ++VS+LA L +L V KG V IY+P++ EAI
Sbjct: 95 TPDKTAYHFVSEDGATS---KLTYQELDNKVSKLANGLKSLRVKKGDVVAIYLPMIQEAI 151
Query: 619 IAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVI 729
+A+LA+ +IGA+ +V+F G++ L R++ V+
Sbjct: 152 LAILASAKIGAVQTVIFSGYSTESLHIRLQDCNAKVL 188
>UniRef50_Q9YCA8 Cluster: Acetyl-coenzyme A synthetase; n=2;
Archaea|Rep: Acetyl-coenzyme A synthetase - Aeropyrum
pernix
Length = 656
Score = 97.1 bits (231), Expect = 4e-19
Identities = 59/163 (36%), Positives = 90/163 (55%), Gaps = 4/163 (2%)
Frame = +1
Query: 256 YEKAQQRSLNDPEGFWGEVGSEL--EWTKPWDRVLDDSNA-PFTKWWVGGEMSVCYNAVD 426
YE+ +RS D + FWG + L EW + V+D S + +W+ GG ++ YN VD
Sbjct: 30 YEELVRRSSEDLKWFWGNLPEWLGVEWFREPKAVVDLSRGVEWAQWYRGGLLNAAYNVVD 89
Query: 427 RHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTT-LGVSKGARVLIYMPL 603
R V G G + A VR+ +Y +LKD+V R+A L+ G+ G V IY P+
Sbjct: 90 RIVKMGYGHREAFTWVGE-DGEVRRYTYLQLKDEVDRMAKLLSQDYGLGVGDVVAIYAPM 148
Query: 604 VPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVII 732
+PE+I AMLA ++GA+ S +F GFA + R++ E V++
Sbjct: 149 MPESIAAMLAAMKVGAVASPIFSGFAPPAVAERLKLGEARVLV 191
>UniRef50_Q6L1R5 Cluster: Acetyl-coenzyme A synthetase; n=1;
Picrophilus torridus|Rep: Acetyl-coenzyme A synthetase -
Picrophilus torridus
Length = 396
Score = 97.1 bits (231), Expect = 4e-19
Identities = 54/162 (33%), Positives = 91/162 (56%)
Frame = +1
Query: 253 EYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRH 432
+Y + ++S+ + +W V SEL W K WD + + P K+++ G +VC+N +DRH
Sbjct: 34 DYYQFYKKSIENIGDYWAGVASELYWFKKWD-INMHGDFPDFKFFLNGYSNVCFNCIDRH 92
Query: 433 VVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPE 612
+ + ++ A++ S + K+ Y L S+ A L ++G+ KG V I+MP E
Sbjct: 93 ALK-KPDKTAIIWLSEDGLEI-KMDYRSLMIYTSKFASYLRSIGIKKGDVVAIFMPNRIE 150
Query: 613 AIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXA 738
+ IA+ A RIGAI++++F GF+ + L R+ P VII A
Sbjct: 151 SFIAVHACYRIGAIYNIIFSGFSTKALLDRLYETMPKVIITA 192
>UniRef50_A3VFU7 Cluster: Acetoacetyl-CoA synthase; n=1;
Rhodobacterales bacterium HTCC2654|Rep: Acetoacetyl-CoA
synthase - Rhodobacterales bacterium HTCC2654
Length = 667
Score = 94.3 bits (224), Expect = 3e-18
Identities = 53/164 (32%), Positives = 83/164 (50%), Gaps = 2/164 (1%)
Frame = +1
Query: 256 YEKAQQRSLNDPEGFWGEVGSELEWTKPWD--RVLDDSNAPFTKWWVGGEMSVCYNAVDR 429
Y + Q S+ DP GFW V + + +VL D P T+W+ G ++ N + R
Sbjct: 41 YRELQVWSVEDPAGFWRAVWDYFDVIHEGEIEQVLTDDPMPRTRWFTGTRLNYAENIL-R 99
Query: 430 HVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVP 609
H +G E+ ++H + + IS+ E+ QV +LA ++ +G+ G RV+ YMP +P
Sbjct: 100 HETSGDPERPMMMHCAETRPDIAAISWAEVAGQVRKLATRMREMGIEPGDRVVAYMPNIP 159
Query: 610 EAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXAS 741
E IAMLAT IG I S F A+ + R EP ++ +
Sbjct: 160 ETFIAMLATTAIGGIWSSAAPEFGAQTVIDRFSQIEPKLVFAVT 203
>UniRef50_Q9Y8M8 Cluster: Acetyl-coenzyme A synthetase; n=1;
Aeropyrum pernix|Rep: Acetyl-coenzyme A synthetase -
Aeropyrum pernix
Length = 140
Score = 93.9 bits (223), Expect = 4e-18
Identities = 48/115 (41%), Positives = 68/115 (59%), Gaps = 1/115 (0%)
Frame = +1
Query: 271 QRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRG 450
++S+ D E FW E EL W KPW +VLD APF +W+VGGE ++ NA+DR +
Sbjct: 24 RKSIEDIERFWDERARELVWLKPWHQVLDRGKAPFYRWFVGGETNINLNALDRWIGTSVE 83
Query: 451 EQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTT-LGVSKGARVLIYMPLVPE 612
+ A + D R +SY +L +V+RLA L +GV G RV IY+P++PE
Sbjct: 84 NKVAYYWEGEPGDR-RVLSYGDLYREVNRLAYALKEYIGVKPGDRVAIYLPMIPE 137
>UniRef50_Q5V498 Cluster: Acyl-coenzyme A synthetases; n=5;
Halobacteriaceae|Rep: Acyl-coenzyme A synthetases -
Haloarcula marismortui (Halobacterium marismortui)
Length = 673
Score = 92.3 bits (219), Expect = 1e-17
Identities = 53/151 (35%), Positives = 83/151 (54%), Gaps = 5/151 (3%)
Frame = +1
Query: 292 EGFWGEVGS--ELEWTKPWDRVLDDSNAP-FTKWWVGGEMSVCYNAVDRHVVNGRGEQ-- 456
E FW + ++E+ +D+V D+S P FT W+ GG ++ +N +DRH +
Sbjct: 56 EWFWDLLPEYLDIEFFDAYDQVRDNSEGPQFTDWYAGGTINAAHNVLDRHAARDSPTRNT 115
Query: 457 FALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLAT 636
AL+ + D VR+I+Y+EL Q S++A L ++GV G V +YMP+VPE +
Sbjct: 116 VALIWEGEPGD-VREITYHELNRQASKVANYLESVGVGTGDTVGLYMPMVPEVASILYGC 174
Query: 637 NRIGAIHSVVFGGFAARELRTRIEHAEPTVI 729
++GAI +F GF TRI AE +V+
Sbjct: 175 LKVGAIAVPIFSGFGVDATATRIADAECSVL 205
>UniRef50_Q97WK0 Cluster: Acetyl-CoA synthetase; n=4;
Sulfolobaceae|Rep: Acetyl-CoA synthetase - Sulfolobus
solfataricus
Length = 571
Score = 90.2 bits (214), Expect = 5e-17
Identities = 49/161 (30%), Positives = 85/161 (52%), Gaps = 1/161 (0%)
Frame = +1
Query: 253 EYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLD-DSNAPFTKWWVGGEMSVCYNAVDR 429
+Y SL PE +W + L + K W++V++ + P KW++ G ++ YNA++
Sbjct: 2 DYYTLYDLSLEKPETYWETFANRLSFFKKWEKVIEKNKQLPIAKWFINGTTNIAYNALNH 61
Query: 430 HVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVP 609
G+ AL+ +I+++EL + S +AG L GV +G R+ IYMP
Sbjct: 62 ---GGK----ALIFYQENKHKGDEITFDELNNMSSMIAGLLLDKGVRRGDRIAIYMPNSI 114
Query: 610 EAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVII 732
I +LA R+GAI++++F G + +RI + EP ++I
Sbjct: 115 CTIATILAAARLGAIYTLIFAGLGINAIVSRISNLEPKLVI 155
>UniRef50_Q4ST59 Cluster: Chromosome undetermined SCAF14300, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF14300,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 737
Score = 89.4 bits (212), Expect = 8e-17
Identities = 46/117 (39%), Positives = 70/117 (59%), Gaps = 1/117 (0%)
Frame = +1
Query: 391 GGEMSVCYNAVDRHVVNGR-GEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGV 567
G ++CYN +DR+V + G++ A + ++Y EL +V + A L + GV
Sbjct: 3 GASTNICYNVLDRNVHEKKLGDKVAFYWEGNEPGDELTVTYRELLQRVCQFANVLKSRGV 62
Query: 568 SKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXA 738
KG RV IYMP+V E ++AMLA RIGA+HS+VF GF++ L RI ++ ++I A
Sbjct: 63 KKGDRVSIYMPMVVELVVAMLACARIGAVHSIVFAGFSSESLCERILDSQCCLLITA 119
>UniRef50_Q3E187 Cluster: AMP-dependent synthetase and
ligase:Enoyl-CoA hydratase/isomerase; n=2; Chloroflexus
aurantiacus|Rep: AMP-dependent synthetase and
ligase:Enoyl-CoA hydratase/isomerase - Chloroflexus
aurantiacus J-10-fl
Length = 1822
Score = 88.6 bits (210), Expect = 1e-16
Identities = 49/146 (33%), Positives = 75/146 (51%), Gaps = 11/146 (7%)
Frame = +1
Query: 334 KPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRGEQFALVHDSPLTD-------- 489
+PW + DDS APF +W+ GG + C+N VDRHV+ G G++ A + D
Sbjct: 87 QPWQQAFDDSEAPFYRWFSGGLTNACFNEVDRHVMMGYGDEVAYYFEGDRWDNSLNNGRG 146
Query: 490 ---TVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHS 660
I+ L +V + A L LG+ KG R+ + MP + I A R+G +++
Sbjct: 147 GPVVQETITRRRLLVEVVKAAQVLRDLGLKKGDRIALNMPNIMPQIYYTEAAKRLGILYT 206
Query: 661 VVFGGFAARELRTRIEHAEPTVIIXA 738
VFGGF+ + L RI +A V+I +
Sbjct: 207 PVFGGFSDKTLSDRIHNAGARVVITS 232
>UniRef50_A3WE14 Cluster: Acetyl-coenzyme A synthetase; n=1;
Erythrobacter sp. NAP1|Rep: Acetyl-coenzyme A synthetase
- Erythrobacter sp. NAP1
Length = 1850
Score = 84.6 bits (200), Expect = 2e-15
Identities = 45/146 (30%), Positives = 77/146 (52%), Gaps = 11/146 (7%)
Frame = +1
Query: 334 KPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRK---- 501
+PW+R +D + P +W+ GG S +N VDRHV++G G++ A++ + + +
Sbjct: 95 EPWERAFNDDDPPNWRWFEGGLTSTAFNEVDRHVLSGHGDEAAMIFEGDRWNMASEGGRG 154
Query: 502 -------ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHS 660
IS +L + ++ A L LG+ G R+ + MP +PE I R+G +++
Sbjct: 155 GPVDSEVISRRKLLLESAKCALALKALGLEAGDRIALNMPSIPEQIYWTEGAKRMGIVYT 214
Query: 661 VVFGGFAARELRTRIEHAEPTVIIXA 738
VFGGF+ + L RI A V++ A
Sbjct: 215 PVFGGFSDKTLSDRIADAGARVVVTA 240
>UniRef50_O30042 Cluster: Acetyl-CoA synthetase; n=1; Archaeoglobus
fulgidus|Rep: Acetyl-CoA synthetase - Archaeoglobus
fulgidus
Length = 662
Score = 84.6 bits (200), Expect = 2e-15
Identities = 55/163 (33%), Positives = 84/163 (51%), Gaps = 2/163 (1%)
Frame = +1
Query: 256 YEKAQQRSLNDPEGFWGEVGS--ELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDR 429
Y+ + S+ + E FW V E++ + VLD+ P KW+ G ++ +A
Sbjct: 47 YKNLWKWSVENLEDFWESVWEFFEIKSYSDYKTVLDERKMPGAKWFEGATLNYAEHAF-- 104
Query: 430 HVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVP 609
+ G GE V + L R ++++EL+ Q + A L +GV KG RV+ Y VP
Sbjct: 105 -LKAGEGEAVVYVREDGLR---RALTWSELERQTAAFAAWLKDMGVKKGDRVVAYCSQVP 160
Query: 610 EAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXA 738
EA+IA+LAT IGAI + V G A R + R + EP V+I +
Sbjct: 161 EAVIALLATASIGAIWAAVGGEVAPRAVIDRFKQLEPKVLIAS 203
>UniRef50_Q0RXR5 Cluster: Acetate--CoA ligase; n=1; Rhodococcus sp.
RHA1|Rep: Acetate--CoA ligase - Rhodococcus sp. (strain
RHA1)
Length = 654
Score = 84.2 bits (199), Expect = 3e-15
Identities = 55/156 (35%), Positives = 82/156 (52%), Gaps = 4/156 (2%)
Frame = +1
Query: 286 DPEGFWGEVGS--ELEWTKPWDRVLDDSNAPF-TKWWVGGEMSVCYNAVDRHVVNGRGEQ 456
DP FW V +LEW + V D +AP TKW+ GG +++ NAVDR + GRG
Sbjct: 48 DPGWFWSYVADWLQLEWQREPTSVFDQLDAPHNTKWFPGGALNITDNAVDRWIRAGRGND 107
Query: 457 FALVHDSPLTD-TVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLA 633
AL + L D + + ++++L ++ R+A L G+ G V I +P+V EA +A LA
Sbjct: 108 TALSWE--LEDGSSGRWTFSQLSLEIDRVARGLIDAGIGFGDTVGIQLPMVREAAVAQLA 165
Query: 634 TNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXAS 741
+IGAI +F GF + R+ A I +S
Sbjct: 166 CAKIGAISVPIFSGFGTAAVIDRLRIAGAKAHIMSS 201
>UniRef50_A5UY60 Cluster: AMP-dependent synthetase and ligase; n=2;
Roseiflexus|Rep: AMP-dependent synthetase and ligase -
Roseiflexus sp. RS-1
Length = 1912
Score = 84.2 bits (199), Expect = 3e-15
Identities = 45/146 (30%), Positives = 76/146 (52%), Gaps = 11/146 (7%)
Frame = +1
Query: 334 KPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRK---- 501
+PW+R + + PF +W+ GG + C+N VDRHV+ G G++ A + D+
Sbjct: 85 EPWERAFNGDDPPFYRWFEGGLTNACFNEVDRHVLTGYGDEVAFYFEGDRWDSSLNNGRG 144
Query: 502 -------ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHS 660
++ +L +V + A L LG+ G R+ + MP + E I A R+G I++
Sbjct: 145 GPVVSFAVTRKQLMLEVVKAAQVLRDLGLKTGDRIALNMPNIMEQIYYTEAAKRLGIIYT 204
Query: 661 VVFGGFAARELRTRIEHAEPTVIIXA 738
VFGGF+ + L RI +A ++I +
Sbjct: 205 PVFGGFSDKTLSDRIHNAGARLVITS 230
>UniRef50_A7JC22 Cluster: Predicted protein; n=1; Francisella
tularensis subsp. tularensis FSC033|Rep: Predicted
protein - Francisella tularensis subsp. tularensis
FSC033
Length = 147
Score = 83.4 bits (197), Expect = 5e-15
Identities = 42/108 (38%), Positives = 60/108 (55%), Gaps = 1/108 (0%)
Frame = +1
Query: 256 YEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPF-TKWWVGGEMSVCYNAVDRH 432
YEK + SL +PE FW + + + W KP+ + + S AP KW+ GE++VCYN VDRH
Sbjct: 23 YEKLYKESLENPEQFWTKQANRIHWHKPFTKAYNSSFAPVDIKWFDDGELNVCYNCVDRH 82
Query: 433 VVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKG 576
+ R Q A + + +KI+Y EL +V +A L GV KG
Sbjct: 83 -LPARANQVAFIWQADNPKKSKKITYRELYHRVCEMANILEANGVKKG 129
>UniRef50_Q397N8 Cluster: Acetoacetyl-CoA synthase; n=5;
Bacteria|Rep: Acetoacetyl-CoA synthase - Burkholderia
sp. (strain 383) (Burkholderia cepacia (strain ATCC
17760/ NCIB 9086 / R18194))
Length = 665
Score = 82.6 bits (195), Expect = 9e-15
Identities = 51/164 (31%), Positives = 80/164 (48%), Gaps = 2/164 (1%)
Frame = +1
Query: 253 EYEKAQQRSLNDPEGFWGEVGS--ELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVD 426
+Y+ + S+ +P+ FW + +++ RV D + P T+W+ ++ + +
Sbjct: 38 DYDALWRWSVREPDAFWASIWQWYGVQYDGSARRVTDGAPMPHTRWFPDARVNYAEHVLQ 97
Query: 427 RHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLV 606
G F H + T ++ +S EL QV R+A +L LGV G RV+ Y+P V
Sbjct: 98 NAAHAGAAPAF---HYASETRPLQTMSLAELASQVRRVATRLRDLGVVPGDRVVAYLPNV 154
Query: 607 PEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXA 738
PE +AMLAT IGAI S F R + R + P V+I A
Sbjct: 155 PECAVAMLATTAIGAIWSSAAIDFGVRTVVDRFQQIAPKVLIAA 198
>UniRef50_A4T5I6 Cluster: Acetoacetyl-CoA synthase; n=2;
Mycobacterium|Rep: Acetoacetyl-CoA synthase -
Mycobacterium gilvum PYR-GCK
Length = 637
Score = 80.6 bits (190), Expect = 4e-14
Identities = 49/163 (30%), Positives = 80/163 (49%)
Frame = +1
Query: 250 PEYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDR 429
P+Y S+ D E FW + + + VL + P +W+ G E++ + V R
Sbjct: 38 PDYHALWAWSVEDVEEFWAALWDYFDLGERAQPVLQSAEMPGAQWFPGTEINYV-DQVMR 96
Query: 430 HVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVP 609
HV R + D+P R++S+ EL + + A +L GV G RV+ Y+P +P
Sbjct: 97 HVRTDRPAILHVSEDAP----DREVSWAELLGRTAAFADRLRAAGVESGDRVVGYLPNIP 152
Query: 610 EAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXA 738
EA++A LAT IGA+ S ++A+ R+ EP ++ A
Sbjct: 153 EAVVAFLATASIGAVWSACGQDYSAKAALDRLGQLEPKALVAA 195
>UniRef50_Q54YU2 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 261
Score = 79.8 bits (188), Expect = 7e-14
Identities = 43/130 (33%), Positives = 72/130 (55%)
Frame = +1
Query: 334 KPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYN 513
K ++ + + +N +W+ G ++ CYNA+D+H+VNGRGE+ A VH+ P +I+Y
Sbjct: 27 KEYENIYNSNN---NEWFSSGLLNACYNALDKHIVNGRGEEIAFVHEIPSKQISTQITYK 83
Query: 514 ELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAAREL 693
+L D+V + V+IYM + II+ L+ RIGA H+++FGG+ + L
Sbjct: 84 QLFDKVCDI--------------VIIYMQNSIKLIISTLSCCRIGATHNIIFGGYTQKGL 129
Query: 694 RTRIEHAEPT 723
+ PT
Sbjct: 130 SYLLNIYSPT 139
>UniRef50_Q9KZN9 Cluster: Acetoacetyl-CoA synthetase; n=5;
Actinobacteria (class)|Rep: Acetoacetyl-CoA synthetase -
Streptomyces coelicolor
Length = 658
Score = 79.4 bits (187), Expect = 9e-14
Identities = 47/160 (29%), Positives = 84/160 (52%), Gaps = 2/160 (1%)
Frame = +1
Query: 256 YEKAQQRSLNDPEGFWGEVGS--ELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDR 429
Y + S+++ + FW V ++ ++ P RVL D P +W+ G ++ +A+
Sbjct: 41 YAALHRWSVDELDTFWKAVTEWFDVRFSTPCARVLGDRTMPGAQWFPGATLNYAEHAL-- 98
Query: 430 HVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVP 609
R ++ AL++ T +++ EL+ QV+ LA +L LGV G RV Y+P +P
Sbjct: 99 RAAGTRPDEPALLYVDE-THEPAPVTWAELRRQVASLAAELRALGVRPGDRVSGYLPNIP 157
Query: 610 EAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVI 729
+A++A+LAT +G + + F AR + R + EP V+
Sbjct: 158 QAVVALLATAAVGGVWTSCAPDFGARSVLDRFQQVEPVVL 197
>UniRef50_Q01NM8 Cluster: AMP-dependent synthetase and ligase; n=1;
Solibacter usitatus Ellin6076|Rep: AMP-dependent
synthetase and ligase - Solibacter usitatus (strain
Ellin6076)
Length = 610
Score = 79.4 bits (187), Expect = 9e-14
Identities = 44/157 (28%), Positives = 81/157 (51%), Gaps = 3/157 (1%)
Frame = +1
Query: 277 SLNDPEGFWGEVGSEL--EWTKPWDRVLDDSNAP-FTKWWVGGEMSVCYNAVDRHVVNGR 447
S +PE FWGE+ E+ EW P+ + LD S P + +W++GG +++ +N +DR +
Sbjct: 38 SRENPERFWGEMMREMRVEWFTPYSKELDLSGGPEWARWFIGGRLNIAHNCLDRWADS-- 95
Query: 448 GEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAM 627
+ A + + + +++ EL++Q +R A L LG+ G RV + +P+ PE + +
Sbjct: 96 -DCAACIWEGE-SGAGGTLTFRELREQANRTANGLRALGLEAGDRVALCLPMTPEILPIL 153
Query: 628 LATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXA 738
+ G +F GF + TR+ + V+ A
Sbjct: 154 YGCFKAGLTVVPIFAGFGTGAIATRLIDSGACVLFTA 190
>UniRef50_A3W6I7 Cluster: AMP-dependent synthetase and ligase; n=2;
Rhodobacteraceae|Rep: AMP-dependent synthetase and
ligase - Roseovarius sp. 217
Length = 645
Score = 77.4 bits (182), Expect = 4e-13
Identities = 47/165 (28%), Positives = 86/165 (52%), Gaps = 4/165 (2%)
Frame = +1
Query: 256 YEKAQQRSLNDPEGFWGEV--GSELEWTKPWDRVLDDSNAPFT-KWWVGGEMSVCYNAVD 426
YE +R+ P+ FW + + + +++P+ ++ D P + +W VG +++ +D
Sbjct: 26 YEDLVRRANAAPDWFWRRIIDHAGIRFSRPYLQLRDIFKGPESIRWAVGAALNLTETCLD 85
Query: 427 RHVVNGRGEQFALVHDSPLTDTVRKI-SYNELKDQVSRLAGKLTTLGVSKGARVLIYMPL 603
+ G ++ +V D D R+ +Y EL + +R+A L GV G RV IYMP+
Sbjct: 86 ARIEEGLADK--MVIDWVGEDASRRCWTYAELAAETARVASALAARGVKPGERVGIYMPM 143
Query: 604 VPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXA 738
+PE A+L R+GA+ +F GFA + +R++ A ++ A
Sbjct: 144 IPEIAAALLGIARLGAVAVPLFSGFAPPAIVSRLQDAGAVAVLTA 188
>UniRef50_Q12HA7 Cluster: Acetoacetyl-CoA synthase precursor; n=6;
Proteobacteria|Rep: Acetoacetyl-CoA synthase precursor -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 696
Score = 76.2 bits (179), Expect = 8e-13
Identities = 52/165 (31%), Positives = 79/165 (47%), Gaps = 6/165 (3%)
Frame = +1
Query: 256 YEKAQQRSLNDPEGFWGEVGS--ELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDR 429
Y+ + S+ D E FW + EL+ P VL D P +W+ G +++ + R
Sbjct: 27 YDALWRWSVTDLEAFWQSIWDYFELQSPTPHTAVLADRRMPGARWFPGAQVNYARQVL-R 85
Query: 430 HVVNGRGEQF-ALVHD---SPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYM 597
HV F ALV+ S + R++S+ L+ QV+ LA L GV G RV Y+
Sbjct: 86 HVDKAHAAGFPALVNHNEKSLASGQHRELSWPALRQQVASLALHLKAQGVEPGDRVAAYL 145
Query: 598 PLVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVII 732
P +PEA++A LA IG + S+ + R + EP V+I
Sbjct: 146 PNIPEAMVAFLAVVSIGGVWSICAPDMGTHAVLDRFKQIEPKVLI 190
>UniRef50_A5WDS3 Cluster: AMP-dependent synthetase and ligase; n=5;
Gammaproteobacteria|Rep: AMP-dependent synthetase and
ligase - Psychrobacter sp. PRwf-1
Length = 554
Score = 74.9 bits (176), Expect = 2e-12
Identities = 37/101 (36%), Positives = 59/101 (58%)
Frame = +1
Query: 427 RHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLV 606
RHV NG G++ ALVH+ + ++S+NEL + +++A L GV G RV +P
Sbjct: 48 RHVRNGLGDKVALVHEDT-KQKITQLSFNELDQRSAQVANLLKAYGVKAGDRVATMLPRT 106
Query: 607 PEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVI 729
PE +I +LAT R+GAI+ +F F + R++ A+ V+
Sbjct: 107 PELLIVVLATWRVGAIYQPLFTAFGVESIAYRLDKADTKVV 147
>UniRef50_Q86JR9 Cluster: Putative uncharacterized protein; n=2;
Dictyostelium discoideum|Rep: Putative uncharacterized
protein - Dictyostelium discoideum (Slime mold)
Length = 400
Score = 74.5 bits (175), Expect = 2e-12
Identities = 48/155 (30%), Positives = 76/155 (49%), Gaps = 1/155 (0%)
Frame = +1
Query: 289 PEGFWGEVGSE-LEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRGEQFAL 465
PE FW EV + + W K +D+V + W+ +G+Q AL
Sbjct: 21 PEAFWDEVAKKNVFWDKMYDKVYSGDEM-YPDWF-------------------KGDQDAL 60
Query: 466 VHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRI 645
+++ P K++Y++L ++V + L L +SK VLIYM EA IA+L+
Sbjct: 61 IYECPYLKKTVKLTYHQLYEKVCEFSRVLLNLNISKNDNVLIYMANTVEAPIAILSCTHN 120
Query: 646 GAIHSVVFGGFAARELRTRIEHAEPTVIIXASCGV 750
GA H V+F G++ + L RIE P +II + G+
Sbjct: 121 GATHCVLFDGYSVKSLIDRIETITPKLIITTNYGI 155
>UniRef50_UPI00005102FE Cluster: COG0365: Acyl-coenzyme A
synthetases/AMP-(fatty) acid ligases; n=1;
Brevibacterium linens BL2|Rep: COG0365: Acyl-coenzyme A
synthetases/AMP-(fatty) acid ligases - Brevibacterium
linens BL2
Length = 680
Score = 74.1 bits (174), Expect = 3e-12
Identities = 48/159 (30%), Positives = 81/159 (50%), Gaps = 4/159 (2%)
Frame = +1
Query: 277 SLNDPEGFWGEVGS--ELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRG 450
S+ D E FW V +++ P+ VL++ P +W+ G ++ +++ G
Sbjct: 43 SITDIEDFWESVWEYFDVKSHSPYTSVLEERVMPHARWFTGATLNYAEHSL------GAP 96
Query: 451 EQFALVHDSPLTDTVRK--ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIA 624
EQ V + ++ T ++Y EL+ +V+R+ L LGV KG RV+ Y+P PEA++A
Sbjct: 97 EQADEVAVTAVSQTREDFTLTYAELRREVARVRAGLIDLGVKKGDRVVGYLPNQPEALVA 156
Query: 625 MLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXAS 741
LA +GAI + F + + R EPTV++ S
Sbjct: 157 FLAAASLGAIWASCAPEFGTQSVIDRFSQVEPTVLLAIS 195
>UniRef50_Q5KZW6 Cluster: Acetoacetyl-CoA synthetase; n=20;
Bacteria|Rep: Acetoacetyl-CoA synthetase - Geobacillus
kaustophilus
Length = 667
Score = 72.1 bits (169), Expect = 1e-11
Identities = 48/160 (30%), Positives = 80/160 (50%), Gaps = 2/160 (1%)
Frame = +1
Query: 256 YEKAQQRSLNDPEGFWGEVGSE--LEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDR 429
Y + S+ E FW V ++ P++ VL + P +W+ G ++ + + R
Sbjct: 46 YRELWTWSVEHLEEFWETVWEYCGVQAATPYECVLRERKMPGAEWFPGAALNYAKH-IFR 104
Query: 430 HVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVP 609
H R ++ A++ S R++S+ EL ++ + +A L +GV +G RV+ YMP +P
Sbjct: 105 HA---RADRPAIIFRSERVP-YREVSWQELGEKTAAIAKALRAMGVKRGDRVVAYMPNIP 160
Query: 610 EAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVI 729
E ++A LA IGAI S F A + R EPTV+
Sbjct: 161 ETVMAFLACASIGAIWSSCSPDFGAGSVIDRFAQIEPTVL 200
>UniRef50_P39062 Cluster: Acetyl-coenzyme A synthetase; n=41;
cellular organisms|Rep: Acetyl-coenzyme A synthetase -
Bacillus subtilis
Length = 572
Score = 71.7 bits (168), Expect = 2e-11
Identities = 39/118 (33%), Positives = 62/118 (52%), Gaps = 1/118 (0%)
Frame = +1
Query: 382 WWVGGEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTL 561
W G+++ Y A+DRH + R + AL + D K ++ E+K++ +R L
Sbjct: 36 WHETGKLNAAYEAIDRHAESFRKNKVALYYKDAKRD--EKYTFKEMKEESNRAGNVLRRY 93
Query: 562 G-VSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVII 732
G V KG RV I+MP PE ML +IGAI +F F ++ R+E++E V++
Sbjct: 94 GNVEKGDRVFIFMPRSPELYFIMLGAIKIGAIAGPLFEAFMEGAVKDRLENSEAKVVV 151
>UniRef50_A4QIB2 Cluster: Putative uncharacterized protein; n=1;
Corynebacterium glutamicum R|Rep: Putative
uncharacterized protein - Corynebacterium glutamicum
(strain R)
Length = 675
Score = 70.9 bits (166), Expect = 3e-11
Identities = 45/166 (27%), Positives = 79/166 (47%), Gaps = 3/166 (1%)
Frame = +1
Query: 250 PEYEKAQQRSLNDPEGFWGEVGSELEWT-KPWD--RVLDDSNAPFTKWWVGGEMSVCYNA 420
P++ S+ + E FW + S + + +D VL + PF W+ G ++ N
Sbjct: 44 PDFHSLLDWSVTEVEAFWRSIQSYFDVIGEGFDTSEVLKEHVMPFASWFPGARVNFAENV 103
Query: 421 VDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMP 600
+ RH N ++ + +S+ +L+ QV+ LA LGV +G R+ +P
Sbjct: 104 L-RHAHNPLLANEPAIYQVEEDGSHTVLSWVQLESQVASLAATFKELGVERGDRIAAVLP 162
Query: 601 LVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXA 738
VPEAII +LA IGA+ ++ +A R++ EP V++ +
Sbjct: 163 NVPEAIIGLLAAASIGAVWTINSPDLSAEASIRRVKQLEPKVLVAS 208
>UniRef50_O28347 Cluster: Long-chain-fatty-acid--CoA ligase; n=1;
Archaeoglobus fulgidus|Rep: Long-chain-fatty-acid--CoA
ligase - Archaeoglobus fulgidus
Length = 509
Score = 70.1 bits (164), Expect = 5e-11
Identities = 36/79 (45%), Positives = 48/79 (60%)
Frame = +1
Query: 496 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGG 675
++ISY ELK+ +RLA L LGV KG RV +P+ PE + LA ++IGAI +
Sbjct: 30 KEISYGELKENANRLAASLLKLGVGKGDRVATVLPMTPEYVCTFLACSKIGAICVPMDVR 89
Query: 676 FAARELRTRIEHAEPTVII 732
+ ELR + HAEP VII
Sbjct: 90 YRTAELRRFLSHAEPKVII 108
>UniRef50_A1IEB0 Cluster: Acetoacetyl-CoA synthase; n=1; Candidatus
Desulfococcus oleovorans Hxd3|Rep: Acetoacetyl-CoA
synthase - Candidatus Desulfococcus oleovorans Hxd3
Length = 295
Score = 69.3 bits (162), Expect = 9e-11
Identities = 46/165 (27%), Positives = 80/165 (48%), Gaps = 3/165 (1%)
Frame = +1
Query: 253 EYEKAQQRSLNDPEGFWGEVG--SELEWTKPWDRVLDD-SNAPFTKWWVGGEMSVCYNAV 423
EY++ S+ + FW +++ + P+D V+DD P +W+ G ++ N
Sbjct: 51 EYDELYHWSVRNISDFWAAFWDFAQIRCSSPFDCVVDDVGKMPGARWFEGARLNFAEN-- 108
Query: 424 DRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPL 603
++ R + AL+ + ++R ++Y +L D+V+ L L LG+ G RV +MP
Sbjct: 109 ---LLRYRDDHSALIFKAEGRPSIR-MTYRQLYDEVAGLVISLKALGLKPGDRVAGFMPN 164
Query: 604 VPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXA 738
+P+ IIAMLA +GA S F + + R P V+ A
Sbjct: 165 MPQTIIAMLAATSLGATWSSCSPDFGIKGVMDRFGQIAPKVLFTA 209
>UniRef50_Q8ZV30 Cluster: Acetyl-coenzyme A synthetase; n=6;
Thermoprotei|Rep: Acetyl-coenzyme A synthetase -
Pyrobaculum aerophilum
Length = 626
Score = 68.9 bits (161), Expect = 1e-10
Identities = 48/160 (30%), Positives = 76/160 (47%), Gaps = 6/160 (3%)
Frame = +1
Query: 277 SLNDPEGFWGEVGSE---LEWTKPWDRVLDDSNA-PFTKWWVGGEMSVCYNAVD--RHVV 438
+ + PE FW E L W + + +VLD S + +W+VGG++++ D R +V
Sbjct: 35 TFDKPEEFWRSFEKEVLKLGWYEEYIKVLDLSKGVQWPRWFVGGKINIADQLEDSSRPLV 94
Query: 439 NGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAI 618
GE + SY+E+ + +A L G+ KG RV I+MP+VPE I
Sbjct: 95 KWEGED----------GSTAVWSYSEVLYKAKAVASWLKRNGLEKGDRVAIFMPMVPEII 144
Query: 619 IAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXA 738
ML R G + +F GF +R R+E +E + +
Sbjct: 145 PVMLGAIRAGGVIVPLFSGFGKEAIRVRLEDSEAKFVFAS 184
>UniRef50_Q0S3K9 Cluster: Acetoacetate--CoA ligase; n=10;
Actinomycetales|Rep: Acetoacetate--CoA ligase -
Rhodococcus sp. (strain RHA1)
Length = 647
Score = 68.5 bits (160), Expect = 2e-10
Identities = 51/165 (30%), Positives = 77/165 (46%), Gaps = 4/165 (2%)
Frame = +1
Query: 256 YEKAQQRSLNDPEGFWGEVGSELEW---TKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVD 426
Y + S+ DP FW +V E+ T P + DD+ P W+ G + N VD
Sbjct: 37 YRALWRWSIADPAAFWQDVWDYFEFRSATDPGPALADDA-MPGAVWFPGATL----NYVD 91
Query: 427 RHVVNGR-GEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPL 603
N R G L TD + ++EL+ V+ LA L GV G RV+ Y+P
Sbjct: 92 HVFRNARPGTPAILYAGEGATDV--SVGWDELRSAVAGLAVTLREHGVGVGDRVVGYLPN 149
Query: 604 VPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXA 738
+PEA++A LAT +GA+ + ++A R+ +P +I A
Sbjct: 150 IPEAVVAFLATASLGAVWAACGQDYSAPAALDRLGQLDPKALITA 194
>UniRef50_Q8IWD2 Cluster: Acetoacetyl-CoA synthetase; n=53;
Eumetazoa|Rep: Acetoacetyl-CoA synthetase - Homo sapiens
(Human)
Length = 672
Score = 68.1 bits (159), Expect = 2e-10
Identities = 51/176 (28%), Positives = 80/176 (45%), Gaps = 5/176 (2%)
Frame = +1
Query: 238 CGTTPE-YEKAQQRSLNDPEGFWGEVG--SELEWTKPWDRVLDDSN--APFTKWWVGGEM 402
CG E Y+ S+ FW E S + +++ +D V+D S A +W+ G +
Sbjct: 40 CGLALESYDDLYHWSVESYSDFWAEFWKFSGIVFSRVYDEVVDTSKGIADVPEWFKGSRL 99
Query: 403 SVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGAR 582
+ N + RH N R AL + + K+++ EL+ +V+ A + +GV KG R
Sbjct: 100 NYAENLL-RHKENDR---VALYVAREGKEEIVKVTFEELRQEVALFAAAMRKMGVKKGDR 155
Query: 583 VLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXASCGV 750
V+ Y+P A+ AMLA IGAI S F + R +P +I V
Sbjct: 156 VVGYLPNSEHAVEAMLAAASIGAIWSSTSPDFGVNGVLDRFSQIQPKLIFSVEAVV 211
>UniRef50_A1W234 Cluster: Acetoacetyl-CoA synthase; n=2;
Comamonadaceae|Rep: Acetoacetyl-CoA synthase -
Acidovorax sp. (strain JS42)
Length = 754
Score = 66.9 bits (156), Expect = 5e-10
Identities = 47/163 (28%), Positives = 78/163 (47%), Gaps = 3/163 (1%)
Frame = +1
Query: 253 EYEKAQQRSLNDPEGFWGEVGS--ELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVD 426
+Y+ + S D + FW V +L+ P VL + P +W+ G +++ +
Sbjct: 35 DYDALWRWSTTDLDAFWQSVWDYFDLQSPTPHSAVLAKNVMPGAQWFPGAQVNYARQVL- 93
Query: 427 RHVVNGRGE-QFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPL 603
RHV + Q AL+ + + R++S+ L+ QV+ LA + GV G RV Y+P
Sbjct: 94 RHVDAAQAAGQPALIGRNERGER-RELSWPALRRQVAALALHMRAQGVQPGDRVAAYLPN 152
Query: 604 VPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVII 732
+PE I+A LA IGA+ S+ + R PTV++
Sbjct: 153 IPETIVAFLACASIGAVWSLCAPDMGTHAVLDRFRQIAPTVLL 195
>UniRef50_A1VP64 Cluster: Acetoacetyl-CoA synthase; n=2;
Comamonadaceae|Rep: Acetoacetyl-CoA synthase -
Polaromonas naphthalenivorans (strain CJ2)
Length = 667
Score = 66.9 bits (156), Expect = 5e-10
Identities = 46/163 (28%), Positives = 75/163 (46%), Gaps = 2/163 (1%)
Frame = +1
Query: 247 TPEYEKAQQRSLNDPEGFWGEVGSELEWTKPWDR--VLDDSNAPFTKWWVGGEMSVCYNA 420
T +Y++ + S+ D GFW + E +R + P +W+ ++ +
Sbjct: 42 TQDYDELWRWSIEDLPGFWQSIWDFFEVQADGEREPAMVGEQMPGIQWFPNARLNFAEH- 100
Query: 421 VDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMP 600
V R+ + A +PL R+IS+ EL+ + LA +L + GV G RV +MP
Sbjct: 101 VFRNATSAHPVMLAHTEGAPL----REISWEELERTTAALAAQLRSWGVQPGDRVASFMP 156
Query: 601 LVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVI 729
+PE +IA LA +GAI S A + R+ EP V+
Sbjct: 157 NLPETVIAFLACASVGAIWSSCAPDMGANVVLDRLRQIEPKVL 199
>UniRef50_Q8ESW2 Cluster: Acetoacetyl-CoA synthetase; n=1;
Oceanobacillus iheyensis|Rep: Acetoacetyl-CoA synthetase
- Oceanobacillus iheyensis
Length = 661
Score = 66.5 bits (155), Expect = 7e-10
Identities = 44/162 (27%), Positives = 80/162 (49%), Gaps = 2/162 (1%)
Frame = +1
Query: 253 EYEKAQQRSLNDPEGFWGEVGSELEWTK--PWDRVLDDSNAPFTKWWVGGEMSVCYNAVD 426
+Y + S++D FW + P+ V+ ++ P ++W+ +++ + V
Sbjct: 39 DYASLWKWSVDDISSFWETIWEYFNVISHHPYQHVISSTSMPGSRWFKEAKVNYAEH-VF 97
Query: 427 RHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLV 606
+H N A++H S T ++IS+ +L + L L +GV+KG RV+ Y P +
Sbjct: 98 KHKDNSNP---AIIHASE-TRGKQEISWQQLYQDTTALQLTLKNIGVTKGDRVVSYAPNI 153
Query: 607 PEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVII 732
E ++A LAT+ +GAI S F + + R + EP V+I
Sbjct: 154 YETVVAFLATSSLGAIWSSASPDFGKQSVIERFQQIEPKVMI 195
>UniRef50_Q0A597 Cluster: AMP-dependent synthetase and ligase; n=2;
Ectothiorhodospiraceae|Rep: AMP-dependent synthetase and
ligase - Alkalilimnicola ehrlichei (strain MLHE-1)
Length = 553
Score = 66.5 bits (155), Expect = 7e-10
Identities = 41/113 (36%), Positives = 59/113 (52%)
Frame = +1
Query: 394 GEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSK 573
G +++ Y A+DRHV G G+ ALV L + R SY EL + +R AG L GV
Sbjct: 23 GRLNMAYEALDRHVEAGGGDHEALVWRG-LDNERRASSYAELLEASARFAGALRARGVGL 81
Query: 574 GARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVII 732
G RV P PE IA L R GA+ + +F + + +R R+ +E V++
Sbjct: 82 GERVCTLAPRRPEPFIAGLGALRQGAVFAPLFPVYGPQPVRQRLTVSEARVLV 134
>UniRef50_Q0SJB1 Cluster: Acetoacetate--CoA ligase; n=1; Rhodococcus
sp. RHA1|Rep: Acetoacetate--CoA ligase - Rhodococcus sp.
(strain RHA1)
Length = 666
Score = 65.7 bits (153), Expect = 1e-09
Identities = 49/169 (28%), Positives = 77/169 (45%), Gaps = 2/169 (1%)
Frame = +1
Query: 232 NVCGTTPEYEKAQQRSLNDPEGFWGEVGSELEW--TKPWDRVLDDSNAPFTKWWVGGEMS 405
NVC T +++ S++D E FW + + + P VL D P +W+ G ++
Sbjct: 34 NVC--TTDFDSLWCWSISDLEKFWLSIWEYFDVIASAPPQTVLSDPRMPGARWFPGTRLN 91
Query: 406 VCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARV 585
N + RH + G V + T T ++S EL QV+ LA +GV G R+
Sbjct: 92 WAENLL-RHT-DRTGPAIISVDE---TGTTGELSRAELVAQVANLAAHFRKIGVQPGDRI 146
Query: 586 LIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVII 732
+P + + A+LA +GA+ S F + L R EPTV+I
Sbjct: 147 AAMLPNIAPTVAAVLAAASVGAVWSCCAPDFGVKGLVDRFAQIEPTVLI 195
>UniRef50_A4TUE0 Cluster: Acyl-coenzyme A synthetases/AMP-(Fatty)
acid ligases; n=5; Proteobacteria|Rep: Acyl-coenzyme A
synthetases/AMP-(Fatty) acid ligases - Magnetospirillum
gryphiswaldense
Length = 588
Score = 64.9 bits (151), Expect = 2e-09
Identities = 43/141 (30%), Positives = 69/141 (48%)
Frame = +1
Query: 310 VGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRGEQFALVHDSPLTD 489
V EL+WT + NA M++ Y AVDRHV GRG++ A++ +
Sbjct: 20 VSPELDWTYARQNLSGPGNAG---------MNIAYAAVDRHVAAGRGDRPAILSLGRRYE 70
Query: 490 TVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVF 669
R++SY +L D +RLA L GV G +V + E +A ++GA++ +F
Sbjct: 71 K-RRLSYAQLADLSARLAAVLAAHGVGAGDKVAVLTGRSVELYVAAFGCWKVGAVYCPLF 129
Query: 670 GGFAARELRTRIEHAEPTVII 732
F L++R+E + V+I
Sbjct: 130 SAFGPGPLKSRLELSRAKVLI 150
>UniRef50_Q8F6X6 Cluster: Acetyl-CoA synthetase; n=3; Bacteria|Rep:
Acetyl-CoA synthetase - Leptospira interrogans
Length = 660
Score = 64.1 bits (149), Expect = 4e-09
Identities = 51/166 (30%), Positives = 82/166 (49%), Gaps = 4/166 (2%)
Frame = +1
Query: 256 YEKAQQRSLNDPEGFWGEVG--SELEWTKPWDRVLDD-SNAPFTKWWVGGEMSVCYNAVD 426
+E+ + S+N+ FW + SE+ ++ +D V SN +K++ G +++ N +
Sbjct: 36 FEELRVWSVNEIGSFWESIWEFSEVVHSQKYDLVYQSGSNFTDSKFFPGAKLNFAENLLR 95
Query: 427 RHVVNGRGEQF-ALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPL 603
R + F AL++ + R++SY EL V +A L GV G RV+ MP
Sbjct: 96 RT------DSFPALIYRGE-DGSKREVSYAELYSYVGAVATDLKKRGVVPGDRVVGLMPN 148
Query: 604 VPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXAS 741
VPE +IAMLAT IGAI S F + + R EP ++ +
Sbjct: 149 VPETVIAMLATTSIGAIWSSCSPDFGVKGVLDRFGQIEPKILFTTN 194
>UniRef50_A4TEH9 Cluster: Acetyl-CoA synthetase precursor; n=1;
Mycobacterium gilvum PYR-GCK|Rep: Acetyl-CoA synthetase
precursor - Mycobacterium gilvum PYR-GCK
Length = 280
Score = 64.1 bits (149), Expect = 4e-09
Identities = 40/117 (34%), Positives = 58/117 (49%), Gaps = 4/117 (3%)
Frame = +1
Query: 394 GEMSVCYNAVDRHVVNGRGEQFAL--VHDSPLTD--TVRKISYNELKDQVSRLAGKLTTL 561
G ++ Y AVDRH G + AL V +S LT +VR + Y+EL SR L L
Sbjct: 42 GLCNIAYAAVDRHAGGSAGGRTALRFVSESALTGETSVRDLEYSELASLSSRFTAVLRAL 101
Query: 562 GVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVII 732
GV KG RV + PE + +L R G++ S +F F + TR+ + V++
Sbjct: 102 GVGKGDRVFTLLGRCPELYVTILGALRNGSVVSPLFSAFGPEPVATRLRLGDAHVLV 158
>UniRef50_A0JS90 Cluster: AMP-dependent synthetase and ligase; n=16;
Bacteria|Rep: AMP-dependent synthetase and ligase -
Arthrobacter sp. (strain FB24)
Length = 607
Score = 63.7 bits (148), Expect = 5e-09
Identities = 36/104 (34%), Positives = 51/104 (49%)
Frame = +1
Query: 394 GEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSK 573
G +++ Y AVDRH R AL T R +SY EL +Q R AG L LG+ +
Sbjct: 52 GGVNIAYEAVDRHAAGERAGHEALRFIRS-DGTARSLSYAELAEQTGRFAGVLHRLGIGR 110
Query: 574 GARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRI 705
G RV M PE +A+L T + ++ +F F +R R+
Sbjct: 111 GERVFSLMGRSPELYVAVLGTLKNASVFCPLFSAFGPEPVRQRL 154
>UniRef50_A7IGG1 Cluster: AMP-dependent synthetase and ligase; n=1;
Xanthobacter autotrophicus Py2|Rep: AMP-dependent
synthetase and ligase - Xanthobacter sp. (strain Py2)
Length = 503
Score = 63.3 bits (147), Expect = 6e-09
Identities = 35/114 (30%), Positives = 62/114 (54%)
Frame = +1
Query: 391 GGEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVS 570
G + + + DRH+ R A++H+S ++ ++S+ L D SR A L T+G+
Sbjct: 73 GDAIPLAHLLCDRHLPGKRSHP-AMIHES-VSGQTSELSFGRLADYSSRFARVLATIGIR 130
Query: 571 KGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVII 732
KG V + +P E IIA LA R+GA++ +F ++A + R+E ++ I+
Sbjct: 131 KGDCVAVMLPKGVELIIAALAIWRVGAVYMPLFSTYSASAVNARLESSDVKAIV 184
>UniRef50_A3JB96 Cluster: Acetyl-coenzyme A synthetase; n=6;
Gammaproteobacteria|Rep: Acetyl-coenzyme A synthetase -
Marinobacter sp. ELB17
Length = 668
Score = 63.3 bits (147), Expect = 6e-09
Identities = 48/169 (28%), Positives = 75/169 (44%), Gaps = 2/169 (1%)
Frame = +1
Query: 241 GTTPEYEKAQQRSLNDPEGFWGEVGSE--LEWTKPWDRVLDDSNAPFTKWWVGGEMSVCY 414
G +Y + + S++D EGFW V L P +VL + P +W+ G ++
Sbjct: 36 GPFADYHELHEWSVSDLEGFWRAVWDYCGLISHTPAQKVLGKRDMPGAEWFPGMTLNFAA 95
Query: 415 NAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIY 594
N + RH + A+V +R+ +Y EL+ V L L + GV KG RV
Sbjct: 96 NLL-RHAEGEQANSEAIVAYCETRPVLRR-TYTELRADVGALEAYLCSQGVIKGDRVAGI 153
Query: 595 MPLVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXAS 741
+ EA++ MLA +GA+ S F + R EPT +I +
Sbjct: 154 VTNGYEAMVGMLAATSMGALWSSASPDFGIGAILDRFGQIEPTALIAVN 202
>UniRef50_Q2J785 Cluster: Acetoacetyl-CoA synthase; n=5;
Actinobacteria (class)|Rep: Acetoacetyl-CoA synthase -
Frankia sp. (strain CcI3)
Length = 709
Score = 62.5 bits (145), Expect = 1e-08
Identities = 46/154 (29%), Positives = 71/154 (46%), Gaps = 2/154 (1%)
Frame = +1
Query: 277 SLNDPEGFWGEVGS--ELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRG 450
S+ D + FW + +E + L D+ P W+ G ++ NA+ R G
Sbjct: 71 SVTDLDTFWESIWDFCAVEGDRGTGPALADAAMPGAVWFPGARVNYAENALTRR---GPA 127
Query: 451 EQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAML 630
V + T V S++EL+ QV++ A L +LGV++G RV +P A++ ML
Sbjct: 128 PAVIAVREDGATAVV---SWDELRRQVAKAAAGLRSLGVAEGDRVCAVLPNTVYAMVGML 184
Query: 631 ATNRIGAIHSVVFGGFAARELRTRIEHAEPTVII 732
AT IGA+ S LR R +P V+I
Sbjct: 185 ATASIGAVWSSCSPELGPTALRARFGQIDPKVLI 218
>UniRef50_Q7W0W3 Cluster: Acetyl-CoA synthetase; n=2;
Bordetella|Rep: Acetyl-CoA synthetase - Bordetella
parapertussis
Length = 543
Score = 61.7 bits (143), Expect = 2e-08
Identities = 41/116 (35%), Positives = 57/116 (49%)
Frame = +1
Query: 382 WWVGGEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTL 561
W + + + +DRH +GR ALV R SY EL +Q R A L L
Sbjct: 23 WGEAHAVDLAHAIIDRHRASGRT---ALVFIDQQGRESRH-SYAELAEQSDRAANLLARL 78
Query: 562 GVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVI 729
GV G RV +P PE ++AMLA +IGAI+ +F GF + R+ H+ V+
Sbjct: 79 GVRPGDRVAGLLPRGPEILVAMLAAIKIGAIYVPIFTGFKRDAIEYRLGHSGARVV 134
>UniRef50_Q11QU1 Cluster: Acetyl-CoA synthetase; n=1; Cytophaga
hutchinsonii ATCC 33406|Rep: Acetyl-CoA synthetase -
Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)
Length = 653
Score = 61.3 bits (142), Expect = 2e-08
Identities = 42/145 (28%), Positives = 73/145 (50%), Gaps = 2/145 (1%)
Frame = +1
Query: 277 SLNDPEGFWGEVGSEL--EWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRG 450
S++ EGFW + L ++ +P+ VL+ S+ P W+ + +N V+
Sbjct: 73 SIDKKEGFWKAMIDSLSIKFEQPYSSVLEKSDDPDQVHWL---KNARFNIVES-CFQAAS 128
Query: 451 EQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAML 630
EQ A+ + + + + ISY LK +V + A L+ G + R+++Y+P +AI L
Sbjct: 129 EQAAIFYQAEQSSEIHTISYGALKQKVIQYASGLSKNGFAAHDRIILYLPFSIDAIAFYL 188
Query: 631 ATNRIGAIHSVVFGGFAARELRTRI 705
A +GA +V F+A+EL RI
Sbjct: 189 ACIYMGAEPVLVSDSFSAQELTKRI 213
>UniRef50_Q5KW92 Cluster: Acetyl-CoA synthetase; n=2;
Geobacillus|Rep: Acetyl-CoA synthetase - Geobacillus
kaustophilus
Length = 552
Score = 60.9 bits (141), Expect = 3e-08
Identities = 32/113 (28%), Positives = 61/113 (53%)
Frame = +1
Query: 394 GEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSK 573
G + + DR+ + + AL +++ L + + I+Y +L+D +++A LGV K
Sbjct: 29 GRFNAAHEVCDRYAEDPN--RIALFYENALGEQ-KTITYRQLRDWSNQMANVFRKLGVKK 85
Query: 574 GARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVII 732
G RV MP P ++ +LA ++GA++ +F F + + RI H+E V++
Sbjct: 86 GDRVCALMPKNPALVVYILAAWKVGAVYVPLFTAFGPQAIEYRINHSEAKVLL 138
>UniRef50_Q39MD9 Cluster: AMP-dependent synthetase and ligase; n=2;
Burkholderia|Rep: AMP-dependent synthetase and ligase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 650
Score = 60.9 bits (141), Expect = 3e-08
Identities = 46/167 (27%), Positives = 82/167 (49%), Gaps = 5/167 (2%)
Frame = +1
Query: 256 YEKAQQRSLNDPEGFWGEVGSE--LEWTKPWDRVLDDSN-APFTKWWVGGEMSVCYN--A 420
Y++ + S+ +PE +W V E + W P +D S A F W+ GG+++ A
Sbjct: 34 YDELMRVSIAEPERYWDTVMRECAIAWDVPPTGYVDLSRGAQFPSWFPGGKLNWVNTIYA 93
Query: 421 VDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMP 600
RH +Q A+V + +V +++ EL+ +V A L GV +G R+ + M
Sbjct: 94 WARHPATA--QQKAVVAERE-DGSVSTLTFAELEQRVQDFAAGLARHGVKQGDRIGLLME 150
Query: 601 LVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXAS 741
EA +++LA +GA+ +F GF + R+ AE ++I ++
Sbjct: 151 NGVEATVSLLAIVHLGALVVPLFSGFGVDAIVARLSAAEARMVIAST 197
>UniRef50_A6C4K4 Cluster: Acetate--CoA ligase; n=1; Planctomyces
maris DSM 8797|Rep: Acetate--CoA ligase - Planctomyces
maris DSM 8797
Length = 679
Score = 60.5 bits (140), Expect = 4e-08
Identities = 28/95 (29%), Positives = 52/95 (54%)
Frame = +1
Query: 445 RGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIA 624
+ EQ A++ TD V+++SY EL+ +R+A LT G+ G R+ + +P+ PE++
Sbjct: 160 KSEQIAILFQRS-TDEVQQLSYRELRALTARVANGLTEAGIEPGERIAVMLPMTPESVAI 218
Query: 625 MLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVI 729
L G + + F+A E++ R++ P +I
Sbjct: 219 FLGIIAAGCVVVTIADSFSAEEMQVRLKITAPRLI 253
>UniRef50_Q5UWB7 Cluster: Acyl-coenzyme A synthetases; n=2;
Halobacteriaceae|Rep: Acyl-coenzyme A synthetases -
Haloarcula marismortui (Halobacterium marismortui)
Length = 616
Score = 60.5 bits (140), Expect = 4e-08
Identities = 38/134 (28%), Positives = 69/134 (51%)
Frame = +1
Query: 340 WDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNEL 519
WD + D++ W ++++ + DRH + RG Q AL + + K+++ EL
Sbjct: 75 WDDIYADAD-----WDAPNDLNIGHEVADRHATD-RG-QVAL-YQVGTDGELSKMTFWEL 126
Query: 520 KDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELRT 699
D+ S+ A L LGV++G RV YMP +PE +A++ T + GA+ V F +
Sbjct: 127 ADRSSQFANVLDDLGVAQGDRVFSYMPRIPEHYVALVGTLKHGAVWGSVNERFGPDGISY 186
Query: 700 RIEHAEPTVIIXAS 741
R++ + V++ +
Sbjct: 187 RLDDCDAKVVVTTT 200
>UniRef50_Q7WPR9 Cluster: AMP-binding enzyme; n=5;
Burkholderiales|Rep: AMP-binding enzyme - Bordetella
bronchiseptica (Alcaligenes bronchisepticus)
Length = 649
Score = 59.7 bits (138), Expect = 8e-08
Identities = 42/166 (25%), Positives = 78/166 (46%), Gaps = 4/166 (2%)
Frame = +1
Query: 256 YEKAQQRSLNDPEGFWGEVGSE--LEWTKPWDRVLDDSNAP-FTKWWVGGEMSVCYNAVD 426
Y+ + S+ +PE +W V E + W +P +D + P F W+ GG ++ N +
Sbjct: 35 YDDLMRVSVEEPERYWNTVMRECAIAWDEPPTGYVDLARGPQFPSWFPGGRLN-WVNTIY 93
Query: 427 RHVVN-GRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPL 603
N Q A++ + +V ++Y EL+ +V A L G G R+ + M
Sbjct: 94 AWARNPATAGQTAVIGERE-DGSVGSLTYQELETRVREFAAGLARHGARPGDRIGLLMEN 152
Query: 604 VPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXAS 741
+A +++LA +GA+ +F GF + R+ AE ++I ++
Sbjct: 153 GVDATVSLLAIVHLGALVVPLFSGFGVDAIVARLSAAEARMVIAST 198
>UniRef50_Q5P869 Cluster: 3-hydroxybenzoate CoA ligase; n=2;
Rhodocyclaceae|Rep: 3-hydroxybenzoate CoA ligase -
Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum
(strain EbN1))
Length = 523
Score = 58.8 bits (136), Expect = 1e-07
Identities = 40/113 (35%), Positives = 56/113 (49%)
Frame = +1
Query: 394 GEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSK 573
G M+ + R + G GEQ A+V R +SY EL V+R L GV++
Sbjct: 10 GTMNAADEIIGRPLSLGLGEQAAIVSGE------RSVSYRELNAMVNRTGNALKEHGVAR 63
Query: 574 GARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVII 732
G RVL M PE + A L T RIGA+ + A R++R IE +E V++
Sbjct: 64 GERVLFLMDDSPEMVAAYLGTLRIGAVSVALNVRLAPRDVRYVIEDSECRVLM 116
>UniRef50_A4FEF5 Cluster: AMP-dependent synthetase and ligase; n=4;
Bacteria|Rep: AMP-dependent synthetase and ligase -
Saccharopolyspora erythraea (strain NRRL 23338)
Length = 571
Score = 57.6 bits (133), Expect = 3e-07
Identities = 29/79 (36%), Positives = 47/79 (59%)
Frame = +1
Query: 496 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGG 675
R+I+Y EL + +R AG L +GV+ G RV +++P P+ ++AML R GA++ V
Sbjct: 58 RRITYAELDELAARFAGWLDAVGVAPGERVGVFLPNCPQLVVAMLGVLRAGAVYVPVNPM 117
Query: 676 FAARELRTRIEHAEPTVII 732
F ELR + A +V++
Sbjct: 118 FREHELRHELADAGVSVLL 136
>UniRef50_A2SSU3 Cluster: AMP-dependent synthetase and ligase; n=3;
Methanocorpusculum labreanum Z|Rep: AMP-dependent
synthetase and ligase - Methanocorpusculum labreanum
(strain ATCC 43576 / DSM 4855 / Z)
Length = 571
Score = 56.8 bits (131), Expect = 5e-07
Identities = 30/77 (38%), Positives = 44/77 (57%)
Frame = +1
Query: 502 ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFA 681
ISY L +QV A L GV KG V I++P +P+++IA A NRIGA+ ++V
Sbjct: 58 ISYRSLMEQVHACAAGLMQHGVKKGDFVTIFLPNIPQSVIAAYAVNRIGAVCNLVHPLST 117
Query: 682 ARELRTRIEHAEPTVII 732
ELR +E E +++
Sbjct: 118 KDELRYAVELTESRIVL 134
>UniRef50_A6QV87 Cluster: Putative uncharacterized protein; n=2;
Pezizomycotina|Rep: Putative uncharacterized protein -
Ajellomyces capsulatus NAm1
Length = 747
Score = 56.4 bits (130), Expect = 7e-07
Identities = 46/163 (28%), Positives = 78/163 (47%), Gaps = 5/163 (3%)
Frame = +1
Query: 256 YEKAQQRSLNDPEGFWGEVG--SELEWTKPWDRVLDDSNAPFTK--WWVGGEMSVCYNAV 423
Y + S+++P FW E+ + ++ K +D+VLD F K ++ G ++ N +
Sbjct: 48 YHDLWEWSISEPSAFWEEIWYFTGVKAQKSYDKVLDKGTPLFPKPVFFKGSLLNFAENLL 107
Query: 424 DRHVVNGRGEQFALVHDSPLTDTVRK-ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMP 600
+ GE + + T++ R+ IS+ +L+ +V R A L GV KG RV ++
Sbjct: 108 --FPASNPGENSVAIIAA--TESTREHISWKDLRARVHRCALSLREAGVVKGDRVAGFVG 163
Query: 601 LVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVI 729
+IAMLA IGA+ S V + R+ EP V+
Sbjct: 164 NHANTVIAMLAATSIGALWSSVSTDTGVNAVLERLRQIEPVVL 206
>UniRef50_A0KEL2 Cluster: Acetoacetyl-CoA synthase; n=2;
Aeromonas|Rep: Acetoacetyl-CoA synthase - Aeromonas
hydrophila subsp. hydrophila (strain ATCC 7966 / NCIB
9240)
Length = 645
Score = 56.0 bits (129), Expect = 9e-07
Identities = 28/76 (36%), Positives = 42/76 (55%)
Frame = +1
Query: 502 ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFA 681
+S+ EL DQV+RLA L G+ +G V Y+P +P+ ++AMLAT +GAI + F
Sbjct: 115 LSWRELADQVARLAQWLRGQGIGRGDVVAAYLPNIPQTVVAMLATTSLGAIWTSTSPDFG 174
Query: 682 ARELRTRIEHAEPTVI 729
+ R P V+
Sbjct: 175 EASVVERFGQTRPRVL 190
>UniRef50_UPI0000510398 Cluster: COG0365: Acyl-coenzyme A
synthetases/AMP-(fatty) acid ligases; n=1;
Brevibacterium linens BL2|Rep: COG0365: Acyl-coenzyme A
synthetases/AMP-(fatty) acid ligases - Brevibacterium
linens BL2
Length = 597
Score = 55.6 bits (128), Expect = 1e-06
Identities = 36/147 (24%), Positives = 64/147 (43%)
Frame = +1
Query: 292 EGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRGEQFALVH 471
E W + + L+W D + T W+ G + +N + RH+ + ++ AL
Sbjct: 10 ESNWRPIINTLDWEVEPDELFRPDPTGGT-WFPGARIDALHNLLLRHL-DTHSDRLALHW 67
Query: 472 DSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGA 651
+ D ++Y EL D V+ L LGV G RV ++ +P +AMLA +GA
Sbjct: 68 EGEPGDR-ESLTYRELADDVATFTAALQKLGVGAGDRVALHTGWLPSTAVAMLACTGLGA 126
Query: 652 IHSVVFGGFAARELRTRIEHAEPTVII 732
+++ L + PT+++
Sbjct: 127 PWTLIPVSLPVEALSQKFAQLNPTLVV 153
>UniRef50_Q7WNN5 Cluster: Putative long-chain-fatty-acid-CoA ligase;
n=5; Bordetella|Rep: Putative long-chain-fatty-acid-CoA
ligase - Bordetella bronchiseptica (Alcaligenes
bronchisepticus)
Length = 539
Score = 55.2 bits (127), Expect = 2e-06
Identities = 29/77 (37%), Positives = 43/77 (55%)
Frame = +1
Query: 502 ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFA 681
+SY+ L V A L LGV +G RV + P PEAII LA R+GA+ + +
Sbjct: 37 LSYSRLLAVVDEAAALLARLGVRRGDRVALLSPPRPEAIITFLACTRLGAVWLALNPKYK 96
Query: 682 ARELRTRIEHAEPTVII 732
A E+ ++HA PT+++
Sbjct: 97 APEIHYILDHARPTLLM 113
>UniRef50_A6FGF6 Cluster: Probable AMP-binding enzyme; n=1;
Moritella sp. PE36|Rep: Probable AMP-binding enzyme -
Moritella sp. PE36
Length = 743
Score = 55.2 bits (127), Expect = 2e-06
Identities = 28/81 (34%), Positives = 47/81 (58%)
Frame = +1
Query: 499 KISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGF 678
++SY +L+++V+R+A + LG+ KG RV +P EA++AMLAT IGAI S F
Sbjct: 137 QLSYLQLREEVTRIAAAMRELGIVKGDRVAGLLPNCSEAVVAMLATTSIGAIWSSCSPDF 196
Query: 679 AARELRTRIEHAEPTVIIXAS 741
+ + R +P ++ +
Sbjct: 197 GHQGVLDRFIQIQPKLLFACN 217
>UniRef50_Q83DG9 Cluster: Acetoacetyl-CoA synthase; n=5;
Gammaproteobacteria|Rep: Acetoacetyl-CoA synthase -
Coxiella burnetii
Length = 650
Score = 54.4 bits (125), Expect = 3e-06
Identities = 48/161 (29%), Positives = 73/161 (45%), Gaps = 3/161 (1%)
Frame = +1
Query: 256 YEKAQQRSLNDPEGFWGEVGSELEWTK---PWDRVLDDSNAPFTKWWVGGEMSVCYNAVD 426
Y Q S++ P FW V + P + ++ ++W++G +++ N +
Sbjct: 38 YPALYQWSIDQPALFWKAVWDFCGISASQAPTNVLVRGKRMEESQWFLGAKLNFAENLL- 96
Query: 427 RHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLV 606
RH R + AL+ S T R I+Y EL +V+ LAG L V G RV+ +
Sbjct: 97 RH----RNQNVALIFTSE-TGFSRSITYAELYTEVAALAGFLRQCHVVPGDRVVGVLSNQ 151
Query: 607 PEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVI 729
E +IAMLAT +GAI S F L R +P V+
Sbjct: 152 IETVIAMLATASVGAIWSACSPDFGLEGLVDRFGQIKPKVL 192
>UniRef50_UPI000038E2AC Cluster: hypothetical protein Faci_03000151;
n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical
protein Faci_03000151 - Ferroplasma acidarmanus fer1
Length = 646
Score = 54.0 bits (124), Expect = 4e-06
Identities = 45/161 (27%), Positives = 77/161 (47%), Gaps = 2/161 (1%)
Frame = +1
Query: 256 YEKAQQRSLNDPEGFWGEVG--SELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDR 429
Y++ + S+ +PE FW + S L+ + ++ +L ++N +W+ G + N DR
Sbjct: 39 YKELWEWSVKNPEIFWISLADFSGLDLGE-YNSILSENNVN-ARWFEGARV----NYADR 92
Query: 430 HVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVP 609
V R + A + + I+Y+ L +VS LA + G++ V Y+ +P
Sbjct: 93 -VYRMRNIEKAAIISYNEEGKEQVITYHSLWQKVSSLAAYFQSNGIAASDTVCAYIGNIP 151
Query: 610 EAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVII 732
EA+I +LAT IGAI S F + + R P V+I
Sbjct: 152 EAVITLLATASIGAIWSSCSPDFGIKGVIERFSQISPKVLI 192
>UniRef50_Q11M02 Cluster: Acetoacetyl-CoA synthase; n=7;
Proteobacteria|Rep: Acetoacetyl-CoA synthase -
Mesorhizobium sp. (strain BNC1)
Length = 652
Score = 54.0 bits (124), Expect = 4e-06
Identities = 31/79 (39%), Positives = 41/79 (51%)
Frame = +1
Query: 496 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGG 675
R+IS++ELK VSRL GV G R+ MP +PE + AMLA +GA+ S
Sbjct: 114 RRISWHELKALVSRLQQLFKAEGVKAGDRIAGMMPNMPETVAAMLAAASLGAVWSSCSPD 173
Query: 676 FAARELRTRIEHAEPTVII 732
F R + R EP + I
Sbjct: 174 FGVRGVLDRFGQIEPVLFI 192
>UniRef50_Q6MYU7 Cluster: Acetoacetyl-coa synthetase, putative; n=6;
Pezizomycotina|Rep: Acetoacetyl-coa synthetase, putative
- Aspergillus fumigatus (Sartorya fumigata)
Length = 699
Score = 54.0 bits (124), Expect = 4e-06
Identities = 42/171 (24%), Positives = 78/171 (45%), Gaps = 4/171 (2%)
Frame = +1
Query: 229 YNVCGTTPEYEKAQQRSLNDPEGFWGEVG--SELEWTKPWDRVLDDSNAPFTK--WWVGG 396
Y +C Y+ Q S++ P FW E+ + ++ K +DRV+ F + ++ G
Sbjct: 41 YQLC--LQNYKDLWQWSISRPSEFWEEIWHYTNIKAHKQYDRVMSSEKLLFPRPHFFEGS 98
Query: 397 EMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKG 576
+++ N + + + E V + +D +S+ EL+++V + A L G+ G
Sbjct: 99 KLNFAENLL--YPASSPAEDTTAVISATESDR-EFVSWKELRERVRKCANSLREAGLQAG 155
Query: 577 ARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVI 729
RV ++ +IAMLAT IGA + V + R+ EP ++
Sbjct: 156 DRVAGFLGNHANTVIAMLATTSIGAYWTGVSPDTGVHAVLERLRQIEPKIL 206
>UniRef50_Q3IUK7 Cluster: Acyl-CoA synthetase I 5; n=2;
Halobacteriaceae|Rep: Acyl-CoA synthetase I 5 -
Natronomonas pharaonis (strain DSM 2160 / ATCC 35678)
Length = 544
Score = 54.0 bits (124), Expect = 4e-06
Identities = 37/126 (29%), Positives = 60/126 (47%)
Frame = +1
Query: 355 DDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVS 534
+ + A FT W + + + Y+ V +H R F D + S+ +L D+
Sbjct: 13 EQATAEFT-WDIPNDYNAAYDLVGKHEHADRPALFQAYPDGRREE----YSFGDLDDESD 67
Query: 535 RLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHA 714
RLA L LGV +G RV + +P VP I LA ++GA+ + F L+ R++ +
Sbjct: 68 RLANALADLGVGRGDRVGVVLPQVPANPITHLACWKLGAVSMPLSVLFGPDGLQYRLDDS 127
Query: 715 EPTVII 732
E TV +
Sbjct: 128 EATVAV 133
>UniRef50_Q8YBS1 Cluster: ACETYL-COENZYME A SYNTHETASE; n=38;
Proteobacteria|Rep: ACETYL-COENZYME A SYNTHETASE -
Brucella melitensis
Length = 568
Score = 53.2 bits (122), Expect = 7e-06
Identities = 27/101 (26%), Positives = 50/101 (49%)
Frame = +1
Query: 400 MSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGA 579
++ C DR+ GE +H + +T+ ++++ +L+D +R+ L G+S G
Sbjct: 50 INACIECCDRYT----GENRVALHAISIDNTLTELTFEDLRDMSARVGNMLADAGISAGD 105
Query: 580 RVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELRTR 702
V +P PE + +L RIGAI+ +F F + + R
Sbjct: 106 VVAGLLPRTPELVATILGAWRIGAIYQPLFTAFGPKAIEQR 146
>UniRef50_Q8G3C8 Cluster: Acetoacetyl-CoA synthase; n=36;
Proteobacteria|Rep: Acetoacetyl-CoA synthase - Brucella
suis
Length = 662
Score = 52.0 bits (119), Expect = 2e-05
Identities = 43/159 (27%), Positives = 72/159 (45%), Gaps = 2/159 (1%)
Frame = +1
Query: 250 PEYEKAQQRSLNDPEGFWGEVGS--ELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAV 423
P+Y + S+ D GFW V + + + D + K++ ++ N +
Sbjct: 45 PDYAALHRWSVEDRAGFWQLVWDFCSVIGERGNTALTDRGHMRAAKFFPEARLNFAENLL 104
Query: 424 DRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPL 603
RH G GE ++ + R++++N+L VS+L + + GV G RV MP
Sbjct: 105 -RH--KGDGEAIVFRGENKVE---RRLTWNDLHALVSKLQQFMLSEGVQPGDRVAGMMPN 158
Query: 604 VPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEP 720
+PEA+ MLA + IGA+ S F + + R EP
Sbjct: 159 MPEAVALMLAASSIGAVWSSCSPDFGVQGVLDRFGQIEP 197
>UniRef50_Q7NVV9 Cluster: Synthetase CbsF; n=3; cellular
organisms|Rep: Synthetase CbsF - Chromobacterium
violaceum
Length = 2859
Score = 52.0 bits (119), Expect = 2e-05
Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Frame = +1
Query: 454 QFALVHDSP-LTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAML 630
Q A D+P L D R +SY E + QV LAG+L GV G V + +P +A++
Sbjct: 2020 QAARTPDAPALLDEARALSYAETRAQVGHLAGRLAEAGVKPGDIVAVALPRSAHLSLALM 2079
Query: 631 ATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXAS 741
A GA + + G+ L + A+P +I+ +
Sbjct: 2080 AAQEAGAAYLPLDTGYPDERLAYMVADAKPALIVTCA 2116
>UniRef50_Q0RL93 Cluster: Putative uncharacterized protein; n=1;
Frankia alni ACN14a|Rep: Putative uncharacterized
protein - Frankia alni (strain ACN14a)
Length = 551
Score = 52.0 bits (119), Expect = 2e-05
Identities = 28/81 (34%), Positives = 44/81 (54%)
Frame = +1
Query: 496 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGG 675
R+++Y E ++ + LAG+ GV K RV + P PE II LA RIGA+ +
Sbjct: 51 RRLTYGEADERSALLAGQFVAAGVGKATRVGMVFPNSPEFIIVWLAIVRIGAVAVPISTL 110
Query: 676 FAARELRTRIEHAEPTVIIXA 738
ELR+ I H++ +++ A
Sbjct: 111 STGTELRSVIRHSDLALLVTA 131
>UniRef50_A5UV13 Cluster: AMP-dependent synthetase and ligase; n=7;
Bacteria|Rep: AMP-dependent synthetase and ligase -
Roseiflexus sp. RS-1
Length = 591
Score = 52.0 bits (119), Expect = 2e-05
Identities = 29/79 (36%), Positives = 44/79 (55%), Gaps = 1/79 (1%)
Frame = +1
Query: 499 KISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGF 678
K++Y +L + V R A L LGV KG RV + +P P +IA A RIGAI +
Sbjct: 63 KMTYQKLSEMVDRFANALYQLGVRKGDRVALMLPNSPHYVIAFFAAMRIGAIIVNNNPTY 122
Query: 679 AARELRTR-IEHAEPTVII 732
AREL+ + ++ T+++
Sbjct: 123 TARELKHQLVDSGSETIVL 141
>UniRef50_A1SEZ8 Cluster: AMP-dependent synthetase and ligase; n=1;
Nocardioides sp. JS614|Rep: AMP-dependent synthetase and
ligase - Nocardioides sp. (strain BAA-499 / JS614)
Length = 541
Score = 52.0 bits (119), Expect = 2e-05
Identities = 34/93 (36%), Positives = 49/93 (52%)
Frame = +1
Query: 460 ALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATN 639
ALV +P D ++S+ L D SRLAG L LGV G RV + +P E IA+LAT
Sbjct: 45 ALVVVAP--DRTTEVSFGRLDDLSSRLAGVLRGLGVGVGDRVAVKLPQSAEMAIAVLATL 102
Query: 640 RIGAIHSVVFGGFAARELRTRIEHAEPTVIIXA 738
++GA+ V + R+E + V++ A
Sbjct: 103 KLGAVVVTVSNVLGVDAVAHRLEDSGALVLVCA 135
>UniRef50_Q21UY9 Cluster: AMP-dependent synthetase and ligase; n=1;
Rhodoferax ferrireducens T118|Rep: AMP-dependent
synthetase and ligase - Rhodoferax ferrireducens (strain
DSM 15236 / ATCC BAA-621 / T118)
Length = 603
Score = 51.6 bits (118), Expect = 2e-05
Identities = 29/79 (36%), Positives = 44/79 (55%)
Frame = +1
Query: 505 SYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAA 684
+Y+EL+ Q +RL+ LT LGV +G RV I MP E +A +A ++GA+ + F
Sbjct: 68 TYSELQAQANRLSNVLTALGVGRGDRVAIVMPQCFETAVAYVAVLQMGAVAMPLSMLFGP 127
Query: 685 RELRTRIEHAEPTVIIXAS 741
+ L R+ E V I A+
Sbjct: 128 QALEFRLHDGEAVVAIGAA 146
>UniRef50_A7I4G3 Cluster: AMP-dependent synthetase and ligase; n=1;
Candidatus Methanoregula boonei 6A8|Rep: AMP-dependent
synthetase and ligase - Methanoregula boonei (strain
6A8)
Length = 519
Score = 51.6 bits (118), Expect = 2e-05
Identities = 29/76 (38%), Positives = 42/76 (55%)
Frame = +1
Query: 505 SYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAA 684
SY EL+D+++R+ L+ LG+ KG RV IY+ PE +I+ A RIGA+ + A
Sbjct: 30 SYRELRDEMNRIGCGLSGLGIQKGDRVCIYLDSSPEYLISYFAIWRIGAVAVPANSVYQA 89
Query: 685 RELRTRIEHAEPTVII 732
EL + A II
Sbjct: 90 EELLHVVRDAGARAII 105
>UniRef50_Q5KZW0 Cluster: Long-chain fatty-acid-CoA ligase; n=6;
Bacillaceae|Rep: Long-chain fatty-acid-CoA ligase -
Geobacillus kaustophilus
Length = 511
Score = 51.2 bits (117), Expect = 3e-05
Identities = 26/77 (33%), Positives = 42/77 (54%)
Frame = +1
Query: 502 ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFA 681
+SY E+ V+RLA L LGV +G +V +YMP E ++ A R+GA+ +
Sbjct: 27 LSYAEVNCMVNRLASSLARLGVGRGDKVALYMPNTKEFAVSYFAVLRLGAVVVPINARLT 86
Query: 682 ARELRTRIEHAEPTVII 732
A E++ + H+E +I
Sbjct: 87 AAEVQYILGHSEAKALI 103
>UniRef50_A2QQX9 Cluster: Contig An08c0110, complete genome; n=6;
Pezizomycotina|Rep: Contig An08c0110, complete genome -
Aspergillus niger
Length = 693
Score = 51.2 bits (117), Expect = 3e-05
Identities = 41/162 (25%), Positives = 74/162 (45%), Gaps = 4/162 (2%)
Frame = +1
Query: 256 YEKAQQRSLNDPEGFWGEVG--SELEWTKPWDRVLDDSNAPFTK--WWVGGEMSVCYNAV 423
Y Q S+++P FW +V + ++ K +DRVL F + ++ G ++ N +
Sbjct: 42 YNDLWQWSVSEPAKFWEDVWKYTSIQAHKSYDRVLRSDKLLFPRPNFFEGTRLNFAENLL 101
Query: 424 DRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPL 603
+ E V + D +++ EL+D+V R A L G+ +G RV ++
Sbjct: 102 --YPSTSPDENAVAVIAATEADR-EFVTWKELRDRVRRCANSLKVSGLQEGDRVAGFLGN 158
Query: 604 VPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVI 729
++AMLAT IGA + V + R++ EP ++
Sbjct: 159 HTNTVVAMLATASIGAFWTGVSPDTGVHAVLERLKQIEPKIL 200
>UniRef50_A1UDV2 Cluster: AMP-dependent synthetase and ligase; n=8;
Mycobacterium|Rep: AMP-dependent synthetase and ligase -
Mycobacterium sp. (strain KMS)
Length = 518
Score = 50.8 bits (116), Expect = 4e-05
Identities = 29/81 (35%), Positives = 46/81 (56%), Gaps = 1/81 (1%)
Frame = +1
Query: 499 KISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGF 678
++ Y + + + +RLA L LG KG V + P E ++ MLA RIGA+ V F F
Sbjct: 30 RLDYGQAERRSARLARGLLALGAGKGTHVGLLYPNGAEFLVGMLAAARIGAV-VVPFSTF 88
Query: 679 A-ARELRTRIEHAEPTVIIXA 738
A AREL ++ H++ +++ A
Sbjct: 89 ATARELAEQLRHSDTEILLSA 109
>UniRef50_A0Y863 Cluster: Long-chain fatty acid--CoA ligase; n=1;
marine gamma proteobacterium HTCC2143|Rep: Long-chain
fatty acid--CoA ligase - marine gamma proteobacterium
HTCC2143
Length = 558
Score = 50.8 bits (116), Expect = 4e-05
Identities = 39/127 (30%), Positives = 68/127 (53%), Gaps = 3/127 (2%)
Frame = +1
Query: 361 SNAPFTKWW-VGGEMSVCYNAVDRHVVNGRGEQFALVH-DSPLTDTV-RKISYNELKDQV 531
SN P W V E+ V +++ + G + +A + D+P R I+Y EL +
Sbjct: 4 SNNPQLPWQHVYDELKVVVPSLECGPLAGYVDDYASSNPDAPALQYFDRCITYIELNCEA 63
Query: 532 SRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEH 711
+RLA L +LGVSK V +++ +P+ +IA++A ++IG S V + EL ++E
Sbjct: 64 NRLANALVSLGVSKDDVVGMHLVNIPQYVIALVAVSKIGCAGSGVSPLMSPNELAYQVED 123
Query: 712 AEPTVII 732
A +V++
Sbjct: 124 AGISVLL 130
>UniRef50_Q0LLG2 Cluster: Amino acid adenylation; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: Amino acid adenylation -
Herpetosiphon aurantiacus ATCC 23779
Length = 1413
Score = 50.4 bits (115), Expect = 5e-05
Identities = 37/115 (32%), Positives = 63/115 (54%), Gaps = 1/115 (0%)
Frame = +1
Query: 391 GGEMSVCYNAV-DRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGV 567
GGE+ + +V +R + N R + AL + +TDT ++SY EL V AG+L GV
Sbjct: 435 GGELRLPLTSVIERILHNARQQPHAL---ALVTDT-EQLSYAELASHVHAWAGQLVQRGV 490
Query: 568 SKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVII 732
+ G+ V + +P EAI+A+LAT GA + + + L + + A+P +++
Sbjct: 491 TAGSVVGVALPRSREAIVAILATLCCGAAYLPLDPQWPQSRLASVVAQAQPVLVL 545
>UniRef50_A4X9C6 Cluster: Thioester reductase domain; n=2;
Salinispora|Rep: Thioester reductase domain -
Salinispora tropica CNB-440
Length = 2376
Score = 50.4 bits (115), Expect = 5e-05
Identities = 30/82 (36%), Positives = 44/82 (53%)
Frame = +1
Query: 487 DTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVV 666
D R +SY +L + +RLAG L LG+ G R +I M EA+ + LA R G I +
Sbjct: 28 DGKRGVSYADLDRRTARLAGHLAALGLETGGRAVILMGNSVEAVESSLAVIRAGGIAVPL 87
Query: 667 FGGFAARELRTRIEHAEPTVII 732
+ E+ ++ AEPTVI+
Sbjct: 88 NPQSSTAEIDHLLDDAEPTVIV 109
>UniRef50_Q87H07 Cluster: Acetyl-CoA synthase; n=13;
Vibrionales|Rep: Acetyl-CoA synthase - Vibrio
parahaemolyticus
Length = 677
Score = 50.0 bits (114), Expect = 6e-05
Identities = 28/78 (35%), Positives = 41/78 (52%)
Frame = +1
Query: 496 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGG 675
+++S +L +QVS + L GV KG V Y+P +PE +IAMLAT +GAI +
Sbjct: 129 KQLSGQQLIEQVSIVQQWLIANGVGKGDVVAAYLPYLPETVIAMLATTSLGAIWTSTSPD 188
Query: 676 FAARELRTRIEHAEPTVI 729
F + R P V+
Sbjct: 189 FGVDSVLERFGQVTPKVL 206
>UniRef50_Q47NR9 Cluster: Non-ribosomal peptide synthase:Amino acid
adenylation; n=1; Thermobifida fusca YX|Rep:
Non-ribosomal peptide synthase:Amino acid adenylation -
Thermobifida fusca (strain YX)
Length = 3629
Score = 50.0 bits (114), Expect = 6e-05
Identities = 26/79 (32%), Positives = 40/79 (50%)
Frame = +1
Query: 505 SYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAA 684
SY L +V RLAG L GV G V + +P VPE + A+LA R+GA++ + F A
Sbjct: 3054 SYARLDAEVERLAGLLVAGGVRPGQVVAVLLPRVPELVAALLAVQRVGAVYVPLDPDFPA 3113
Query: 685 RELRTRIEHAEPTVIIXAS 741
L + + ++ +
Sbjct: 3114 ERLAFMLTDSGAVTVVTTA 3132
Score = 49.6 bits (113), Expect = 8e-05
Identities = 26/63 (41%), Positives = 35/63 (55%)
Frame = +1
Query: 505 SYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAA 684
SY L +V RLAG L GV G V + +P VPE + A+LA R+GA++ + F A
Sbjct: 2008 SYARLDAEVERLAGLLVAGGVRPGQVVAVLLPRVPELVAALLAVQRVGAVYVPLDPDFPA 2067
Query: 685 REL 693
L
Sbjct: 2068 ERL 2070
>UniRef50_Q50E73 Cluster: Peptide synthetase 2; n=1; Streptomyces
filamentosus|Rep: Peptide synthetase 2 - Streptomyces
filamentosus (Streptomyces roseosporus)
Length = 7338
Score = 50.0 bits (114), Expect = 6e-05
Identities = 27/88 (30%), Positives = 44/88 (50%)
Frame = +1
Query: 469 HDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIG 648
HD L +++Y EL + +RLA L G + V + +P E ++A+LA + G
Sbjct: 5205 HDVALVSGNIRLTYAELDARANRLAHLLLARGAAPETFVAVALPRTEELLVALLAVQKTG 5264
Query: 649 AIHSVVFGGFAARELRTRIEHAEPTVII 732
A H + GF A L ++ A P V++
Sbjct: 5265 AGHLPLDPGFPAERLSYMLDDARPAVVL 5292
Score = 46.0 bits (104), Expect = 0.001
Identities = 27/91 (29%), Positives = 43/91 (47%)
Frame = +1
Query: 469 HDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIG 648
HD+ L T +Y EL D+ +RLA L G V + P E+++A+LA + G
Sbjct: 471 HDTALVFTSTSWTYEELNDRANRLARLLVAAGAGSDDFVALAFPRSAESVVAILAVLKAG 530
Query: 649 AIHSVVFGGFAARELRTRIEHAEPTVIIXAS 741
A + + A L + A PTV++ +
Sbjct: 531 AAYLPLDMDQPAERLTGILADAHPTVVLTTT 561
Score = 39.1 bits (87), Expect = 0.11
Identities = 28/102 (27%), Positives = 50/102 (49%)
Frame = +1
Query: 436 VNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEA 615
V RG+ A+V++ + +SY EL + +RLAG L G V + +P +
Sbjct: 2601 VAARGDAPAVVYEGEV------LSYRELDARANRLAGLLVGRGAGPEHFVGVALPRGLDL 2654
Query: 616 IIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXAS 741
I+A+LA + GA + + + A L + A P V++ ++
Sbjct: 2655 IVALLAVLKSGAAYVPLDPEYPAERLVHMVTDAAPVVVVTST 2696
Score = 35.9 bits (79), Expect = 1.1
Identities = 21/78 (26%), Positives = 37/78 (47%)
Frame = +1
Query: 499 KISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGF 678
++SY EL + +RLA L G V + +P P+ ++A+LA + GA + + +
Sbjct: 6270 ELSYRELNTRANRLAHVLAEHGAGPERFVGVALPRSPDLVVALLAVVKSGAAYVPLDPEY 6329
Query: 679 AARELRTRIEHAEPTVII 732
A L A P ++
Sbjct: 6330 PADRLAYMAGDAAPVAVL 6347
>UniRef50_Q0S4D9 Cluster: CoA ligase; n=2; Nocardiaceae|Rep: CoA
ligase - Rhodococcus sp. (strain RHA1)
Length = 553
Score = 50.0 bits (114), Expect = 6e-05
Identities = 30/80 (37%), Positives = 43/80 (53%), Gaps = 1/80 (1%)
Frame = +1
Query: 496 RKISYNELKDQVSRLAGKLTT-LGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFG 672
R++SY E V+ LA L GV KG RV I PE ++A AT +GAI + G
Sbjct: 68 RRMSYTEHAAAVAALATALREDYGVRKGDRVAILAANTPEWVVAFWATQVLGAISVGLNG 127
Query: 673 GFAARELRTRIEHAEPTVII 732
+ RE+ + H+ PTV++
Sbjct: 128 WWVPREVEYGLTHSRPTVVV 147
>UniRef50_Q2H9I4 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 438
Score = 50.0 bits (114), Expect = 6e-05
Identities = 37/163 (22%), Positives = 80/163 (49%), Gaps = 4/163 (2%)
Frame = +1
Query: 253 EYEKAQQRSLNDPEGFWGEVG--SELEWTKPWDRVLDDSNAPFTK--WWVGGEMSVCYNA 420
+Y + + S+++ FWG+V + ++ +KP+D+VL F + ++ G ++ N
Sbjct: 34 DYPQLYKWSVDNVADFWGDVWHFAGIKASKPFDQVLPSEAPMFPRPDFFAGARLNFAENL 93
Query: 421 VDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMP 600
+ V A++ + + + + S+ EL+DQV R + L +GV + + V ++
Sbjct: 94 LFPANVEIDESTTAVITATENDNHLVETSWAELRDQVRRCSNALRAIGVKENSVVAGFVA 153
Query: 601 LVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVI 729
+A++A+L+ IGAI + + + R+ P V+
Sbjct: 154 NHVQALVALLSAATIGAIWTGISPDNGVSAVLDRLTQIRPQVL 196
>UniRef50_P27096 Cluster: Uncharacterized 16.9 kDa protein in acs
3'region; n=1; Methanosaeta concilii|Rep:
Uncharacterized 16.9 kDa protein in acs 3'region -
Methanothrix soehngenii
Length = 145
Score = 50.0 bits (114), Expect = 6e-05
Identities = 20/46 (43%), Positives = 29/46 (63%), Gaps = 1/46 (2%)
Frame = +1
Query: 298 FWGEVGSEL-EWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRH 432
FWGE+ +W +PW L+ P+ KW+VGG+ +V +N VDRH
Sbjct: 87 FWGEMAKTYADWFEPWSSTLE-WKPPYAKWFVGGKCNVTHNCVDRH 131
>UniRef50_Q45R83 Cluster: Peptide synthetase; n=3; Actinobacteria
(class)|Rep: Peptide synthetase - Streptomyces fradiae
Length = 5246
Score = 49.6 bits (113), Expect = 8e-05
Identities = 26/88 (29%), Positives = 44/88 (50%)
Frame = +1
Query: 469 HDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIG 648
H + D R++SY EL D+ +RLA L G V + +P PE I A++A + G
Sbjct: 4191 HAPAVRDGDRELSYAELNDRANRLARFLAARGAGPEDTVAVLLPRGPELITALVAVQKAG 4250
Query: 649 AIHSVVFGGFAARELRTRIEHAEPTVII 732
A + + A + +E+A P +++
Sbjct: 4251 AAYVPMDAELPAERIAHMLENARPVLVL 4278
>UniRef50_Q06YZ2 Cluster: Nonribosomal peptide synthetase; n=1;
Streptomyces fungicidicus|Rep: Nonribosomal peptide
synthetase - Streptomyces fungicidicus
Length = 6943
Score = 49.6 bits (113), Expect = 8e-05
Identities = 26/78 (33%), Positives = 44/78 (56%)
Frame = +1
Query: 499 KISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGF 678
++SY E++++ +RLA KL GV + V + + PE +IA LA + G + V G
Sbjct: 2642 QLSYGEVEERANRLARKLIARGVGPESVVALVLERSPEVVIAALAVLKAGGAYLPVDPGQ 2701
Query: 679 AARELRTRIEHAEPTVII 732
A +R+ IE A P +++
Sbjct: 2702 PAERIRSVIEDAAPVLVL 2719
Score = 47.6 bits (108), Expect = 3e-04
Identities = 25/78 (32%), Positives = 44/78 (56%)
Frame = +1
Query: 499 KISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGF 678
++SY E++++ +RLA KL V + V + + PE +IA+LA + G + + G
Sbjct: 6383 ELSYREVEERANRLARKLIARDVGPESVVALVLERSPELVIAVLAVLKAGGAYLPIDPGQ 6442
Query: 679 AARELRTRIEHAEPTVII 732
A +R+ IE A P ++I
Sbjct: 6443 PAERIRSVIEDAAPVLVI 6460
Score = 36.3 bits (80), Expect = 0.81
Identities = 26/94 (27%), Positives = 44/94 (46%), Gaps = 1/94 (1%)
Frame = +1
Query: 454 QFALVHDSP-LTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAML 630
Q A D+P + ++SY EL + RLA L GV + + V + M + ++A+L
Sbjct: 514 QLAACPDAPAVVCGATELSYAELDTRSDRLARALVAEGVGQESAVAVLMERSIDLVVALL 573
Query: 631 ATNRIGAIHSVVFGGFAARELRTRIEHAEPTVII 732
A + G + G+ R IE A +V++
Sbjct: 574 AVVKAGGAFVPLDTGWPEARKRAVIEDAGASVMV 607
>UniRef50_A0Z3I7 Cluster: Acyl-CoA synthase; n=1; marine gamma
proteobacterium HTCC2080|Rep: Acyl-CoA synthase - marine
gamma proteobacterium HTCC2080
Length = 195
Score = 49.6 bits (113), Expect = 8e-05
Identities = 29/78 (37%), Positives = 41/78 (52%)
Frame = +1
Query: 505 SYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAA 684
SY +L++QV+ LA L LG+ G RV I+ P E ++ LAT +IGAI + +
Sbjct: 49 SYQQLQEQVNSLAAGLLALGIQAGDRVGIWGPNSAEWVMVQLATAKIGAIMVCINPAYRT 108
Query: 685 RELRTRIEHAEPTVIIXA 738
EL + E II A
Sbjct: 109 YELEYALNKVECDTIITA 126
>UniRef50_A0LK08 Cluster: AMP-dependent synthetase and ligase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: AMP-dependent
synthetase and ligase - Syntrophobacter fumaroxidans
(strain DSM 10017 / MPOB)
Length = 549
Score = 49.6 bits (113), Expect = 8e-05
Identities = 35/99 (35%), Positives = 55/99 (55%)
Frame = +1
Query: 397 EMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKG 576
E+++ +DRHV +GRG++ A+ D V I+Y+EL+ V+R L G+
Sbjct: 30 ELNLADYLLDRHVRDGRGDRPAV----KFVDQV--ITYSELQRLVNRFGSSLRDAGLEAR 83
Query: 577 ARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAAREL 693
RV I + PEAII++LA ++GAI +AA E+
Sbjct: 84 DRVGIRLVNCPEAIISVLAVEKLGAIPVPTSPLWAAEEI 122
>UniRef50_Q2NH56 Cluster: Predicted acyl-CoA synthetase; n=1;
Methanosphaera stadtmanae DSM 3091|Rep: Predicted
acyl-CoA synthetase - Methanosphaera stadtmanae (strain
DSM 3091)
Length = 489
Score = 49.6 bits (113), Expect = 8e-05
Identities = 27/82 (32%), Positives = 47/82 (57%)
Frame = +1
Query: 487 DTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVV 666
D ++ + ++ +S + KL LG++KG RVLIY+P PE + + LA RIGA+
Sbjct: 24 DREKRYNSRDILGIISEIGRKLIDLGITKGDRVLIYLPNGPEYLFSFLALWRIGAVAVPT 83
Query: 667 FGGFAARELRTRIEHAEPTVII 732
+ + E++ IE ++ +II
Sbjct: 84 NRIYTSPEIQYFIEDSDAKLII 105
>UniRef50_Q39T59 Cluster: AMP-dependent synthetase and ligase; n=1;
Geobacter metallireducens GS-15|Rep: AMP-dependent
synthetase and ligase - Geobacter metallireducens
(strain GS-15 / ATCC 53774 / DSM 7210)
Length = 539
Score = 49.2 bits (112), Expect = 1e-04
Identities = 30/97 (30%), Positives = 45/97 (46%)
Frame = +1
Query: 442 GRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAII 621
GRG++ A+ +P + R ++NEL R A L +LGV G Y+P PE +
Sbjct: 22 GRGDRVAMRWLTPGMER-RDYTFNELDGLSGRFANVLASLGVGAGEVFFTYLPKQPEQFV 80
Query: 622 AMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVII 732
A L ++ A+ +F F L R+ A II
Sbjct: 81 AFLGALKLTAVAGTLFSNFGEEALLDRLADARACGII 117
>UniRef50_Q3WFP5 Cluster: AMP-dependent synthetase and ligase; n=1;
Frankia sp. EAN1pec|Rep: AMP-dependent synthetase and
ligase - Frankia sp. EAN1pec
Length = 522
Score = 48.8 bits (111), Expect = 1e-04
Identities = 28/76 (36%), Positives = 40/76 (52%)
Frame = +1
Query: 505 SYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAA 684
SY EL +Q R AG L +LGV G RV +P + + A RIGA+ + + AA
Sbjct: 55 SYAELDEQADRAAGALWSLGVRPGDRVAACLPNDLDIVAAFHGAQRIGAVWAGIGEALAA 114
Query: 685 RELRTRIEHAEPTVII 732
E + E +PTV++
Sbjct: 115 SEQQELHEICDPTVVL 130
>UniRef50_Q6L1D6 Cluster: Long chain fatty acid CoA ligase; n=1;
Picrophilus torridus|Rep: Long chain fatty acid CoA
ligase - Picrophilus torridus
Length = 557
Score = 48.8 bits (111), Expect = 1e-04
Identities = 30/94 (31%), Positives = 47/94 (50%)
Frame = +1
Query: 451 EQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAML 630
E+ AL+H T+ +ISY +L ++ + L L G+ KG+ V + MP+VPE A+
Sbjct: 54 EKTALIHYDMDTERSMEISYRDLVNRSNALLSFLRLNGLKKGSIVYLMMPVVPEQWYALT 113
Query: 631 ATNRIGAIHSVVFGGFAARELRTRIEHAEPTVII 732
AT + G I E++ R +P II
Sbjct: 114 ATIKGGMIAIPCATNLTEYEMKNRFSDLKPDAII 147
>UniRef50_Q18HL6 Cluster: O-succinylbenzoic acid--CoA ligase; n=1;
Haloquadratum walsbyi DSM 16790|Rep: O-succinylbenzoic
acid--CoA ligase - Haloquadratum walsbyi (strain DSM
16790)
Length = 506
Score = 48.8 bits (111), Expect = 1e-04
Identities = 29/82 (35%), Positives = 43/82 (52%)
Frame = +1
Query: 487 DTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVV 666
+T ++ L V RLAG+L TLGVS+G R+ I + E+++ A RIGA +
Sbjct: 22 ETGDNYTFAALDQAVERLAGRLITLGVSQGDRLGIVLSPRVESVLIFYAAARIGATAVPL 81
Query: 667 FGGFAARELRTRIEHAEPTVII 732
A E+ TR+ HA +I
Sbjct: 82 GHRLTATEIETRLTHATVQTVI 103
>UniRef50_Q9Z3R3 Cluster: Acetoacetyl-coenzyme A synthetase; n=7;
Proteobacteria|Rep: Acetoacetyl-coenzyme A synthetase -
Rhizobium meliloti (Sinorhizobium meliloti)
Length = 650
Score = 48.8 bits (111), Expect = 1e-04
Identities = 28/78 (35%), Positives = 40/78 (51%)
Frame = +1
Query: 499 KISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGF 678
+++++EL+ VSRL L G+ G RV MP +PE I MLAT +GAI S F
Sbjct: 115 RLTWDELRALVSRLQQALRAQGIGAGDRVAAMMPNMPETIALMLATASVGAIWSSCSPDF 174
Query: 679 AARELRTRIEHAEPTVII 732
+ + R P + I
Sbjct: 175 GEQGVLDRFGQIAPKLFI 192
>UniRef50_Q1GUE8 Cluster: AMP-dependent synthetase and ligase; n=1;
Sphingopyxis alaskensis|Rep: AMP-dependent synthetase
and ligase - Sphingopyxis alaskensis (Sphingomonas
alaskensis)
Length = 571
Score = 48.4 bits (110), Expect = 2e-04
Identities = 26/82 (31%), Positives = 42/82 (51%)
Frame = +1
Query: 496 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGG 675
R+++Y EL ++ RLAG L G+ K +L+ +P + E + A +IGAI S
Sbjct: 55 RRLTYAELAAEIDRLAGALVAAGIGKDDVLLVQLPNIGEFVALYFAAAKIGAIVSPAAVQ 114
Query: 676 FAARELRTRIEHAEPTVIIXAS 741
+ + EL I EP + A+
Sbjct: 115 YRSHELTGMIGVVEPKAFVCAT 136
>UniRef50_A0LLK9 Cluster: Benzoate-CoA ligase family; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: Benzoate-CoA
ligase family - Syntrophobacter fumaroxidans (strain DSM
10017 / MPOB)
Length = 513
Score = 48.4 bits (110), Expect = 2e-04
Identities = 33/102 (32%), Positives = 51/102 (50%)
Frame = +1
Query: 346 RVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKD 525
R + D+ AP V +V +D H + R ++ A+ H + ISY +L+
Sbjct: 3 RFVRDAAAPGRNNAVKSFYNVACELIDGHA-DARPDKTAIYHGA------ETISYRQLRV 55
Query: 526 QVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGA 651
+++R L LGVS G R+LI +P PE +IA L + GA
Sbjct: 56 RINRFGNVLRGLGVSPGERILIALPDCPECVIAFLGGIKCGA 97
>UniRef50_Q6KZU2 Cluster: Acetoacetyl-CoA synthetase; n=1;
Picrophilus torridus|Rep: Acetoacetyl-CoA synthetase -
Picrophilus torridus
Length = 624
Score = 48.4 bits (110), Expect = 2e-04
Identities = 45/163 (27%), Positives = 73/163 (44%), Gaps = 2/163 (1%)
Frame = +1
Query: 256 YEKAQQRSLNDPEGFWGEVGS--ELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDR 429
Y A + S+ D GFW + S +E + R N + W+ E + Y +
Sbjct: 23 YHDAFKNSIKDLNGFWKSLASFYGIELNGSYKR---GENFIDSSWF--NETRINYTDLVL 77
Query: 430 HVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVP 609
N G +++ L + ++IS+NEL V LAG L +G+ KG V Y+
Sbjct: 78 KNKNLNGYSIIYINEK-LNE--KRISWNELSVMVYNLAGFLIEIGLKKGDVVAGYINNNY 134
Query: 610 EAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXA 738
AII+ LA + IG + V F + +R + + P V+I +
Sbjct: 135 YAIISFLAASLIGCTWTCVSQDFGLGAVISRFQQSNPKVLIAS 177
>UniRef50_Q9KLB7 Cluster: Acetyl-CoA synthase; n=21; Vibrio|Rep:
Acetyl-CoA synthase - Vibrio cholerae
Length = 649
Score = 48.0 bits (109), Expect = 2e-04
Identities = 26/78 (33%), Positives = 40/78 (51%)
Frame = +1
Query: 496 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGG 675
+K S+ +L D VS + L GV +G V Y+P +PE +IAMLA +GAI +
Sbjct: 124 KKFSWQQLCDHVSVVQQWLAQNGVGEGDVVAGYLPHLPETVIAMLAATSLGAIWTSTSPD 183
Query: 676 FAARELRTRIEHAEPTVI 729
F + R +P ++
Sbjct: 184 FGVESVIERFGQVQPKIL 201
>UniRef50_Q3IWF1 Cluster: AMP-binding enzyme; n=6;
Alphaproteobacteria|Rep: AMP-binding enzyme -
Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 /
NCIB 8253 / DSM158)
Length = 554
Score = 48.0 bits (109), Expect = 2e-04
Identities = 24/77 (31%), Positives = 43/77 (55%)
Frame = +1
Query: 502 ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFA 681
++Y E++ +V+ LA +L LG+ KG V + +P V + LA RIGA+ + G+
Sbjct: 56 LTYGEMRRKVNGLAARLVALGIGKGTHVGVMLPNVEAFPLTWLALGRIGAVMLPINPGYT 115
Query: 682 ARELRTRIEHAEPTVII 732
RE+ ++ AE ++
Sbjct: 116 PREIAHVMKVAEADWVV 132
>UniRef50_Q13BW2 Cluster: AMP-dependent synthetase and ligase; n=4;
Rhizobiales|Rep: AMP-dependent synthetase and ligase -
Rhodopseudomonas palustris (strain BisB5)
Length = 548
Score = 48.0 bits (109), Expect = 2e-04
Identities = 24/53 (45%), Positives = 34/53 (64%)
Frame = +1
Query: 496 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAI 654
R +SY EL Q+ R+A LT LGV++G RV +++ E + LA NRIGA+
Sbjct: 55 RTLSYRELDAQMRRIAASLTGLGVARGDRVALFLGNCWEFLACTLACNRIGAL 107
>UniRef50_Q0SGL4 Cluster: AMP-dependent synthetase; n=1; Rhodococcus
sp. RHA1|Rep: AMP-dependent synthetase - Rhodococcus sp.
(strain RHA1)
Length = 506
Score = 48.0 bits (109), Expect = 2e-04
Identities = 21/51 (41%), Positives = 32/51 (62%)
Frame = +1
Query: 502 ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAI 654
++Y +L+D +R AG LT G+S G+RVL+ P VPE ++A L G +
Sbjct: 28 LTYGQLRDASTRYAGALTRAGLSPGSRVLLAAPSVPEFVVAYLGIQAAGCV 78
>UniRef50_Q6A9A4 Cluster: Acetyl-coenzyme A synthetase; n=1;
Propionibacterium acnes|Rep: Acetyl-coenzyme A
synthetase - Propionibacterium acnes
Length = 222
Score = 47.6 bits (108), Expect = 3e-04
Identities = 22/42 (52%), Positives = 28/42 (66%)
Frame = +1
Query: 538 LAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSV 663
+A L +GV KG V IY+P +PE AMLA +IGA+HSV
Sbjct: 1 MANVLKVMGVRKGDVVTIYLPRIPEIFFAMLACAKIGAVHSV 42
>UniRef50_Q5D0Q8 Cluster: Nonribosomal peptide synthetase 10; n=15;
Fungi/Metazoa group|Rep: Nonribosomal peptide synthetase
10 - Gibberella moniliformis (Fusarium verticillioides)
Length = 1284
Score = 47.6 bits (108), Expect = 3e-04
Identities = 32/87 (36%), Positives = 44/87 (50%)
Frame = +1
Query: 481 LTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHS 660
L D R ++Y EL + LA +L GV + V + M + +IA LAT R G
Sbjct: 27 LEDEKRSLTYAELDRETWALAERLRDYGVGRDDLVGVLMGRSADYVIAALATLRAGGAFL 86
Query: 661 VVFGGFAARELRTRIEHAEPTVIIXAS 741
V+ + A LR IE A+PTVI+ S
Sbjct: 87 VLEVAYPAGLLRDVIEDAKPTVILTQS 113
>UniRef50_Q0D0Z7 Cluster: Putative uncharacterized protein; n=2;
Pezizomycotina|Rep: Putative uncharacterized protein -
Aspergillus terreus (strain NIH 2624)
Length = 652
Score = 47.6 bits (108), Expect = 3e-04
Identities = 38/162 (23%), Positives = 73/162 (45%), Gaps = 4/162 (2%)
Frame = +1
Query: 256 YEKAQQRSLNDPEGFWGEVGS--ELEWTKPWDRVLDDSNAPFTK--WWVGGEMSVCYNAV 423
Y Q S+++P FW V + ++ +D+VL + F + ++ G ++ N +
Sbjct: 57 YNDLWQWSVSEPANFWEHVWNYTPVKTHSQYDQVLGSDSLLFPRPSFFEGSRLNFAENLL 116
Query: 424 DRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPL 603
+ + E + + D +S+ EL+++V R A L G+ G RV ++
Sbjct: 117 --YPASSPEESDIAIIAATEADR-EYVSWGELRERVRRCANSLKGAGLQAGDRVAGFLGN 173
Query: 604 VPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVI 729
++AMLAT IGA + V + R++ EP ++
Sbjct: 174 HTNTVVAMLATTSIGAFWTGVSPDTGVHAVLERLKQIEPKIL 215
>UniRef50_Q70C44 Cluster: Non-ribosomal peptide synthase; n=1;
Xanthomonas albilineans|Rep: Non-ribosomal peptide
synthase - Xanthomonas albilineans
Length = 941
Score = 47.2 bits (107), Expect = 4e-04
Identities = 23/79 (29%), Positives = 45/79 (56%)
Frame = +1
Query: 496 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGG 675
R++SY +L + +RLA L + GV GARV ++M PE + A+LA + GA + +
Sbjct: 46 RRMSYGQLNTRANRLARLLQSQGVGPGARVAVWMNRSPECLAALLAVMKAGAAYVPIDLS 105
Query: 676 FAARELRTRIEHAEPTVII 732
R ++ ++ ++ +++
Sbjct: 106 LPIRRVQYILQDSQARLVL 124
>UniRef50_Q21EY1 Cluster: Amino acid adenylation; n=1;
Saccharophagus degradans 2-40|Rep: Amino acid
adenylation - Saccharophagus degradans (strain 2-40 /
ATCC 43961 / DSM 17024)
Length = 523
Score = 47.2 bits (107), Expect = 4e-04
Identities = 25/82 (30%), Positives = 44/82 (53%)
Frame = +1
Query: 487 DTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVV 666
D + I+Y EL Q LA +L + GV+ G RV++ +P A+ A++A +GA +
Sbjct: 23 DGTQAITYKELAHQAGSLAARLQSNGVTSGDRVVLLLPKSTTAVCAIIAVLSLGAAYIPA 82
Query: 667 FGGFAARELRTRIEHAEPTVII 732
+ L++ ++ +EP II
Sbjct: 83 DPDAPKQRLQSIVDDSEPKAII 104
>UniRef50_Q124C5 Cluster: AMP-dependent synthetase and ligase; n=4;
Burkholderiales|Rep: AMP-dependent synthetase and ligase
- Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 561
Score = 47.2 bits (107), Expect = 4e-04
Identities = 28/79 (35%), Positives = 42/79 (53%)
Frame = +1
Query: 496 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGG 675
R +SY +L D S L L +LG+ GARV I +P +P+ + M A R G V
Sbjct: 47 RWMSYAQLDDLSSALGAWLQSLGLEPGARVAIMLPNIPQFAVTMAAVLRAGYTCVNVNPL 106
Query: 676 FAARELRTRIEHAEPTVII 732
+ AREL +++ + T I+
Sbjct: 107 YTARELEHQLKDSGATTIV 125
>UniRef50_Q0S7A8 Cluster: 2,3-dihydroxybenzoate-AMP ligase/
S-dihydroxybenzoyltransferase; n=6; Bacteria|Rep:
2,3-dihydroxybenzoate-AMP ligase/
S-dihydroxybenzoyltransferase - Rhodococcus sp. (strain
RHA1)
Length = 550
Score = 47.2 bits (107), Expect = 4e-04
Identities = 29/89 (32%), Positives = 45/89 (50%), Gaps = 3/89 (3%)
Frame = +1
Query: 436 VNGRGEQF--ALVHDSPLTDTV-RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLV 606
+ R EQF A+ P V R ++Y EL D+ RLA L + GV G RV++ +P +
Sbjct: 38 LGARAEQFGDAIAVTGPDASGVDRALTYRELSDRADRLAAGLQSSGVQPGDRVVVQLPNI 97
Query: 607 PEAIIAMLATNRIGAIHSVVFGGFAAREL 693
E + + A R+GA+ A+E+
Sbjct: 98 VEYVEVIFAVFRLGALPVFALPAHRAQEI 126
>UniRef50_A4FFC7 Cluster: Putative fatty-acid--CoA ligase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep: Putative
fatty-acid--CoA ligase - Saccharopolyspora erythraea
(strain NRRL 23338)
Length = 568
Score = 47.2 bits (107), Expect = 4e-04
Identities = 24/72 (33%), Positives = 41/72 (56%)
Frame = +1
Query: 517 LKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELR 696
L+++V+ LA L LG+ +G R+LI M PE +A LA +GA+ + ++ +LR
Sbjct: 10 LREEVAALARGLAGLGLRRGDRMLISMSHRPEHWVADLAAAHVGAVSCTTYDTLSSEQLR 69
Query: 697 TRIEHAEPTVII 732
EH+ V++
Sbjct: 70 FLAEHSAAAVVV 81
>UniRef50_A0QZD4 Cluster: Acetyl-coenzyme A synthetase; n=3;
Corynebacterineae|Rep: Acetyl-coenzyme A synthetase -
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length = 543
Score = 47.2 bits (107), Expect = 4e-04
Identities = 23/77 (29%), Positives = 42/77 (54%)
Frame = +1
Query: 502 ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFA 681
++Y +L++Q ++ A L+ LG+ G V M E ++A+L R GAIH +F FA
Sbjct: 50 LTYGQLREQSTKFAAALSELGIGPGDHVATLMGKSAELVVALLGIWRRGAIHVPLFTAFA 109
Query: 682 ARELRTRIEHAEPTVII 732
+ R+ ++ ++I
Sbjct: 110 PPAITHRLRASDARLVI 126
>UniRef50_UPI000038CCA4 Cluster: COG0318: Acyl-CoA synthetases
(AMP-forming)/AMP-acid ligases II; n=1; Nostoc
punctiforme PCC 73102|Rep: COG0318: Acyl-CoA synthetases
(AMP-forming)/AMP-acid ligases II - Nostoc punctiforme
PCC 73102
Length = 1034
Score = 46.8 bits (106), Expect = 6e-04
Identities = 26/75 (34%), Positives = 39/75 (52%)
Frame = +1
Query: 490 TVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVF 669
T R I+Y +L + + ++A L G SKG + IY P +PE IA A +G I + V
Sbjct: 39 TNRIITYKQLVESIRKIACSLAARGFSKGDVLAIYSPNIPEYAIAFHAVATLGGIITTVN 98
Query: 670 GGFAARELRTRIEHA 714
+ A EL ++ A
Sbjct: 99 PSYTAEELAYQLNDA 113
>UniRef50_Q2BI30 Cluster: Acetyl-coenzyme A synthetase; n=1;
Neptuniibacter caesariensis|Rep: Acetyl-coenzyme A
synthetase - Neptuniibacter caesariensis
Length = 73
Score = 46.8 bits (106), Expect = 6e-04
Identities = 19/51 (37%), Positives = 30/51 (58%), Gaps = 3/51 (5%)
Frame = +1
Query: 253 EYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFT---KWWVGG 396
+Y ++S+NDPE FWGE G ++W KP+ +V + S P +W+ G
Sbjct: 22 KYLAMYEQSVNDPEAFWGEAGKRIDWFKPYTKVKNTSFDPHNVDIRWYEDG 72
>UniRef50_Q28MM6 Cluster: AMP-dependent synthetase and ligase; n=10;
Alphaproteobacteria|Rep: AMP-dependent synthetase and
ligase - Jannaschia sp. (strain CCS1)
Length = 485
Score = 46.8 bits (106), Expect = 6e-04
Identities = 31/91 (34%), Positives = 46/91 (50%)
Frame = +1
Query: 460 ALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATN 639
A+ D P DT +SY +L+ ++ AG L GV+ G RVL + PEA+I LAT
Sbjct: 17 AIFLDVPGGDT---LSYGDLRHAIATAAGALHAAGVAPGDRVLCQIAKSPEALIIYLATV 73
Query: 640 RIGAIHSVVFGGFAARELRTRIEHAEPTVII 732
G + + + EL + AEP ++I
Sbjct: 74 AAGGVFVPLNTAYTPVELDYFLVDAEPALLI 104
>UniRef50_A0LVM6 Cluster: Acetoacetyl-CoA synthase; n=5;
Bacteria|Rep: Acetoacetyl-CoA synthase - Acidothermus
cellulolyticus (strain ATCC 43068 / 11B)
Length = 687
Score = 46.8 bits (106), Expect = 6e-04
Identities = 27/82 (32%), Positives = 43/82 (52%), Gaps = 1/82 (1%)
Frame = +1
Query: 487 DTVRKI-SYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSV 663
D VR+ S+++L+ VSR AG L +G++ G V ++P P+A + LA IGAI +
Sbjct: 147 DGVRETWSWHQLRSTVSRAAGALAAVGITAGDVVAAWLPNCPQAYVVALAAAWIGAIFTS 206
Query: 664 VFGGFAARELRTRIEHAEPTVI 729
F A + R P ++
Sbjct: 207 ASPEFGAPAVLDRFGQVAPKIL 228
>UniRef50_Q0WQ54 Cluster: Acetyl-CoA synthetase-like protein; n=17;
Magnoliophyta|Rep: Acetyl-CoA synthetase-like protein -
Arabidopsis thaliana (Mouse-ear cress)
Length = 295
Score = 46.8 bits (106), Expect = 6e-04
Identities = 39/164 (23%), Positives = 74/164 (45%), Gaps = 6/164 (3%)
Frame = +1
Query: 256 YEKAQQRSLNDPEGFWGEVGSELE--WTKPWDRVLDDSNA---PFTKWWVGGEMSVCYNA 420
+ Q+ S+++PE +W V EL ++ P +L+ + P KW G ++ N
Sbjct: 115 FSSFQEFSVSNPEVYWKTVLDELNILFSVPPKCILEKDTSGDNPGGKWLPGAYLNPARNC 174
Query: 421 VDRHVVNGRGEQFALVHDSPLTDT-VRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYM 597
+ + D D V ++ EL+ QV A L+ LG+ + + + + M
Sbjct: 175 LTNGFKRRLDDIVIRWRDEGSDDLPVNTMTLLELRSQVWLAAHALSALGLEEESAIAVDM 234
Query: 598 PLVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVI 729
P+ E++I LA G + + F+ RE+ TR++ ++ I
Sbjct: 235 PMNVESVIIYLAIVLAGHVVVSIADSFSPREISTRLKISKAKAI 278
>UniRef50_A0V7F5 Cluster: AMP-dependent synthetase and ligase; n=4;
cellular organisms|Rep: AMP-dependent synthetase and
ligase - Delftia acidovorans SPH-1
Length = 713
Score = 46.4 bits (105), Expect = 8e-04
Identities = 30/80 (37%), Positives = 41/80 (51%)
Frame = +1
Query: 502 ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFA 681
ISY EL + R+A L +LGV +G RV++ M P+ I+A A R A+ V
Sbjct: 199 ISYRELCEGTERMAAYLHSLGVQRGDRVILLMQNTPQLILAHYAIFRANAVVVPVNPMNM 258
Query: 682 ARELRTRIEHAEPTVIIXAS 741
A ELR I A+ V I +
Sbjct: 259 AEELRHYITDADAKVAITTA 278
>UniRef50_Q9RLP6 Cluster: Peptide synthetase; n=18; cellular
organisms|Rep: Peptide synthetase - Mycobacterium
smegmatis
Length = 5990
Score = 46.0 bits (104), Expect = 0.001
Identities = 24/87 (27%), Positives = 42/87 (48%)
Frame = +1
Query: 481 LTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHS 660
LT R ++Y EL + +R A L G+ G+RV + P ++IA+L + GA +
Sbjct: 478 LTFEGRTLTYRELDEAANRFAHALLARGIGPGSRVALMSPRTDRSVIAILGAFKAGAAYV 537
Query: 661 VVFGGFAARELRTRIEHAEPTVIIXAS 741
V A +R ++ A P ++ +
Sbjct: 538 PVDPAVPAARVRFILDDASPVAVVTTA 564
Score = 37.1 bits (82), Expect = 0.46
Identities = 20/82 (24%), Positives = 38/82 (46%)
Frame = +1
Query: 496 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGG 675
R +Y EL + +R+A L G G RV + +P EA++ +LA + GA + +
Sbjct: 1980 RSWTYRELDEASNRMAHLLAGRGAKPGERVAMLLPRTGEAVVTILAILKTGAAYLPIDPA 2039
Query: 676 FAARELRTRIEHAEPTVIIXAS 741
+ ++ A P + ++
Sbjct: 2040 HPDARIEFVLKDAAPVAAVSSA 2061
Score = 35.1 bits (77), Expect = 1.9
Identities = 22/82 (26%), Positives = 37/82 (45%)
Frame = +1
Query: 496 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGG 675
R +Y EL + +RLA L G GA V +P EAI+++L+ + GA + V
Sbjct: 3496 RSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPVDPA 3555
Query: 676 FAARELRTRIEHAEPTVIIXAS 741
+ + A+P + +
Sbjct: 3556 HPDARIGFMMSDAKPVAALTTA 3577
>UniRef50_Q9LCU0 Cluster: PstD; n=2; Mycobacterium avium|Rep: PstD -
Mycobacterium avium
Length = 1400
Score = 46.0 bits (104), Expect = 0.001
Identities = 24/82 (29%), Positives = 41/82 (50%)
Frame = +1
Query: 496 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGG 675
R +Y EL + +RLA L+ G G RV + +P EA++A+LA + GA + + G
Sbjct: 461 RSFTYRELYESTNRLAHLLSDHGAGPGQRVAVVIPRSAEAVVAILAVLKTGAAYVPIDPG 520
Query: 676 FAARELRTRIEHAEPTVIIXAS 741
A L+ + + P + +
Sbjct: 521 VPAARLQFVLADSAPVAAVTTA 542
>UniRef50_Q939Z1 Cluster: Peptide synthetase; n=7;
Actinomycetales|Rep: Peptide synthetase - Amycolatopsis
balhimycina
Length = 3165
Score = 46.0 bits (104), Expect = 0.001
Identities = 20/77 (25%), Positives = 43/77 (55%)
Frame = +1
Query: 502 ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFA 681
++Y +L ++ RLAG+L + G+ +G RV + M + ++A+LA + GA + V G+
Sbjct: 35 LTYRQLDERAGRLAGRLASRGIRRGDRVAVVMDRSADLVVALLAVWKAGAAYVPVDAGYP 94
Query: 682 ARELRTRIEHAEPTVII 732
A + + + +++
Sbjct: 95 APRVAFMVADSAAKLVV 111
>UniRef50_A3PSP1 Cluster: AMP-dependent synthetase and ligase; n=18;
Corynebacterineae|Rep: AMP-dependent synthetase and
ligase - Mycobacterium sp. (strain JLS)
Length = 556
Score = 46.0 bits (104), Expect = 0.001
Identities = 27/61 (44%), Positives = 37/61 (60%)
Frame = +1
Query: 472 DSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGA 651
D+ L R ++ EL D+V++LAG L+ GV G RVLI M E I + LA N++GA
Sbjct: 38 DTALRFMGRTTTWGELDDRVTKLAGALSRRGVGFGDRVLILMLNRTEFIESFLAVNKLGA 97
Query: 652 I 654
I
Sbjct: 98 I 98
>UniRef50_A3P7D6 Cluster: Non-ribosomal peptide synthase; n=34;
Bacteria|Rep: Non-ribosomal peptide synthase -
Burkholderia pseudomallei (strain 1106a)
Length = 4468
Score = 46.0 bits (104), Expect = 0.001
Identities = 27/79 (34%), Positives = 40/79 (50%)
Frame = +1
Query: 496 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGG 675
R ++Y EL +RLA L GV G RV +Y PE +I MLAT + G + + G
Sbjct: 570 RALTYAELNRCANRLAHYLRARGVRGGDRVALYARRSPELLIGMLATLKAGGAYVPLDPG 629
Query: 676 FAARELRTRIEHAEPTVII 732
+ A L + + P V++
Sbjct: 630 YPAERLTHILLDSAPVVVL 648
Score = 40.7 bits (91), Expect = 0.037
Identities = 24/89 (26%), Positives = 45/89 (50%)
Frame = +1
Query: 481 LTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHS 660
LT +++SY EL + +RLA L GV G V + E ++ +LA + G +
Sbjct: 1663 LTFEGQRLSYAELNARANRLAHYLQGRGVGPGRLVALCAERGIEMVVGLLAILKAGGAYV 1722
Query: 661 VVFGGFAARELRTRIEHAEPTVIIXASCG 747
+ +A+ LR +E ++P +++ + G
Sbjct: 1723 PLDPAYASDRLRGIVEDSQPALVLADAVG 1751
>UniRef50_Q55RP2 Cluster: Putative uncharacterized protein; n=2;
Filobasidiella neoformans|Rep: Putative uncharacterized
protein - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 698
Score = 46.0 bits (104), Expect = 0.001
Identities = 34/135 (25%), Positives = 61/135 (45%), Gaps = 6/135 (4%)
Frame = +1
Query: 346 RVLDDSNAPFTK--WWVGGEMSVCYNAVDRHVVNGRGEQFALVHD----SPLTDTVRKIS 507
+V+D+ P W+ ++ N + RH R + A++ S ++++I+
Sbjct: 73 KVVDEDKTPEENPPWFTESSLNWAENQL-RHA-KSRPDDIAIIQVCEPCSTYVPSIKQIT 130
Query: 508 YNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAAR 687
EL V + L GV KG RV + EA++ +LAT+ +G I S F
Sbjct: 131 QFELYSLVGKAQRSLRAAGVGKGDRVAFWGGNCLEAVVTVLATSSLGGIFSSAAADFGID 190
Query: 688 ELRTRIEHAEPTVII 732
+ R+E +P V++
Sbjct: 191 GVVERLEQIQPKVLV 205
>UniRef50_Q53005 Cluster: 4-hydroxybenzoate: coenzyme A ligase; n=4;
Rhodopseudomonas palustris|Rep: 4-hydroxybenzoate:
coenzyme A ligase - Rhodopseudomonas palustris
Length = 539
Score = 45.6 bits (103), Expect = 0.001
Identities = 30/107 (28%), Positives = 50/107 (46%)
Frame = +1
Query: 421 VDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMP 600
VDR+V GRG + A + D R +SY EL+D V+R+ L LGV + R+ + +
Sbjct: 13 VDRNVAEGRGGKIAFI------DPQRSLSYGELRDAVARVGPMLARLGVEQENRIALVLK 66
Query: 601 LVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXAS 741
+ I R G + ++ A + R +E + V+ +S
Sbjct: 67 DTVDFPILFWGAIRAGIVPVLLNTRLTADQYRYLLEDSRSRVVFASS 113
>UniRef50_Q3M5Z4 Cluster: AMP-dependent synthetase and ligase; n=5;
Bacteria|Rep: AMP-dependent synthetase and ligase -
Anabaena variabilis (strain ATCC 29413 / PCC 7937)
Length = 662
Score = 45.6 bits (103), Expect = 0.001
Identities = 21/76 (27%), Positives = 41/76 (53%)
Frame = +1
Query: 505 SYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAA 684
+Y +L + +R+A L LG+ +G R+ + +P +PE +I+ L +IGAI + +
Sbjct: 28 TYKQLNEMANRVANALLGLGIERGDRIALLLPNIPEFVISYLGILKIGAIAVSINPNLQS 87
Query: 685 RELRTRIEHAEPTVII 732
EL+ + V++
Sbjct: 88 DELKFILNDCGAAVLV 103
>UniRef50_O34613 Cluster: YtcI; n=53; Bacillales|Rep: YtcI -
Bacillus subtilis
Length = 531
Score = 45.6 bits (103), Expect = 0.001
Identities = 30/105 (28%), Positives = 52/105 (49%), Gaps = 1/105 (0%)
Frame = +1
Query: 406 VCYNAVDR-HVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGAR 582
V YN V+ + G++ AL+ + + SY +L ++ +++ L LG KG +
Sbjct: 13 VQYNLVNEMEKFSAAGQKTALLWEDE-SGKQESWSYEKLMEETNKIGAALADLGFKKGDK 71
Query: 583 VLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAE 717
+++ +P V EA LA + G + A++L RIEHAE
Sbjct: 72 LIVMVPRVLEAYAVYLAILKSGMVVIPCSEMLRAKDLEYRIEHAE 116
>UniRef50_Q24N89 Cluster: Putative uncharacterized protein; n=1;
Desulfitobacterium hafniense Y51|Rep: Putative
uncharacterized protein - Desulfitobacterium hafniense
(strain Y51)
Length = 557
Score = 45.6 bits (103), Expect = 0.001
Identities = 27/77 (35%), Positives = 40/77 (51%)
Frame = +1
Query: 502 ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFA 681
I+Y E RLA + +G+ KG RV+I +P +PE +IA A +IGAI +
Sbjct: 55 ITYYEANTSACRLANAMLDMGIKKGDRVVINLPNMPEFLIAAHACFKIGAIVVPTNPRYT 114
Query: 682 ARELRTRIEHAEPTVII 732
REL + + + II
Sbjct: 115 KRELLCQYLNCKAETII 131
>UniRef50_Q21E99 Cluster: Amino acid adenylation; n=2; Bacteria|Rep:
Amino acid adenylation - Saccharophagus degradans (strain
2-40 / ATCC 43961 / DSM 17024)
Length = 3111
Score = 45.6 bits (103), Expect = 0.001
Identities = 29/107 (27%), Positives = 53/107 (49%)
Frame = +1
Query: 397 EMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKG 576
E + +D H +G+ A+V + + RK +Y EL + +RLA L +G+ KG
Sbjct: 2279 ENKTIIDLIDGHSASGKD---AVVLPNEM-GKARKATYAELTAKSNRLAHNLQNMGIGKG 2334
Query: 577 ARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAE 717
+ V + +P PE I+ +L + GA + + + A + + HA+
Sbjct: 2335 SIVALCLPKSPELIMTLLGVLKAGAAYLPLDPDYPADRISYMLNHAK 2381
>UniRef50_Q1V1I6 Cluster: Acetoacetyl-CoA synthase; n=2;
Bacteria|Rep: Acetoacetyl-CoA synthase - Candidatus
Pelagibacter ubique HTCC1002
Length = 653
Score = 45.6 bits (103), Expect = 0.001
Identities = 33/161 (20%), Positives = 73/161 (45%), Gaps = 2/161 (1%)
Frame = +1
Query: 253 EYEKAQQRSLNDPEGFWGEVG--SELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVD 426
+YE + S+ +P FW + SE++ K ++ K+ + +++ N +
Sbjct: 36 KYESILKWSIENPGNFWSSIWDFSEIKGFKSKIKIKKSKIFYKNKFLLNSKLNFAENLLS 95
Query: 427 RHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLV 606
+ N + + + ++ + + S+ EL VS+++ L ++ + + R+ YMP
Sbjct: 96 K---NNKDKAITFISENSFRE---ERSWQELNLNVSKISKFLKSINIKEKDRLAAYMPNT 149
Query: 607 PEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVI 729
E + A +A++ +GAI S F + + R P V+
Sbjct: 150 IETVEAFIASSSLGAIWSSCSPDFGVKGVVERFSQISPKVL 190
>UniRef50_A6V8H5 Cluster: Long-chain-fatty-acid--CoA ligase,
putative; n=1; Pseudomonas aeruginosa PA7|Rep:
Long-chain-fatty-acid--CoA ligase, putative -
Pseudomonas aeruginosa PA7
Length = 594
Score = 45.6 bits (103), Expect = 0.001
Identities = 27/84 (32%), Positives = 45/84 (53%)
Frame = +1
Query: 481 LTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHS 660
L + +SY +L V R A L GV + V I +P VP+A++A+LA + + A+
Sbjct: 45 LAGAPQALSYRQLLLDVQRFAAALRATGVRQEEAVAILLPFVPQAVVALLAASAV-AVAF 103
Query: 661 VVFGGFAARELRTRIEHAEPTVII 732
V +A +RT++E A V++
Sbjct: 104 PVNLLLSAEAIRTQLELARCRVVV 127
>UniRef50_A4TVS6 Cluster: AMP-dependent synthetase and ligase; n=1;
Magnetospirillum gryphiswaldense|Rep: AMP-dependent
synthetase and ligase - Magnetospirillum gryphiswaldense
Length = 528
Score = 45.6 bits (103), Expect = 0.001
Identities = 32/99 (32%), Positives = 46/99 (46%)
Frame = +1
Query: 436 VNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEA 615
V GR ++ ALV + +SY +L ++V RLA LT LGV +G+RVL+ +
Sbjct: 25 VRGRPDKIALVFSD------QPVSYADLAEEVRRLAAGLTGLGVGRGSRVLVLLKNCRAF 78
Query: 616 IIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVII 732
MLA GA+ V G L T E ++
Sbjct: 79 AALMLAAAERGAVIVPVSAGLRGEALVTAFTATECQFVV 117
>UniRef50_A0K0Y8 Cluster: AMP-dependent synthetase and ligase; n=8;
Bacteria|Rep: AMP-dependent synthetase and ligase -
Arthrobacter sp. (strain FB24)
Length = 583
Score = 45.6 bits (103), Expect = 0.001
Identities = 28/79 (35%), Positives = 40/79 (50%), Gaps = 1/79 (1%)
Frame = +1
Query: 499 KISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGF 678
+ SY EL +S+ A L LGV G RV + MP P+ I+A A R+GA+ +
Sbjct: 61 RTSYRELGALISKAAAGLKKLGVKAGDRVALVMPNCPQHIVAFHAVLRLGAVVVEHNPLY 120
Query: 679 AARELRTRIE-HAEPTVII 732
RELR + E H ++
Sbjct: 121 TDRELRHQFEDHGAAVAVV 139
>UniRef50_A7SU89 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 724
Score = 45.6 bits (103), Expect = 0.001
Identities = 27/90 (30%), Positives = 42/90 (46%)
Frame = +1
Query: 397 EMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKG 576
E + +DRH ++ + D + +++ E KDQ +A +L LGV +G
Sbjct: 2 EHKTLFQLLDRHTAECPNKEALVYRDEK--GNRKSLTFKEYKDQSQAIAARLLELGVVRG 59
Query: 577 ARVLIYMPLVPEAIIAMLATNRIGAIHSVV 666
VL+ +P E I +A RIGAI V
Sbjct: 60 DMVLVMLPSEFEFAIVEIALGRIGAIFVAV 89
>UniRef50_Q62F86 Cluster: AMP-binding domain protein; n=14;
Burkholderia|Rep: AMP-binding domain protein -
Burkholderia mallei (Pseudomonas mallei)
Length = 522
Score = 45.2 bits (102), Expect = 0.002
Identities = 22/53 (41%), Positives = 29/53 (54%)
Frame = +1
Query: 496 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAI 654
R++ Y +L V R A L + G++ G RV Y P E I+ MLA N GAI
Sbjct: 29 RRVRYAQLAADVRRAAAALASAGIAPGERVATYAPKAYETIVTMLAANLAGAI 81
>UniRef50_Q8RNW9 Cluster: Adenylate-forming enzyme; n=2;
Streptomyces|Rep: Adenylate-forming enzyme -
Streptomyces ansochromogenes
Length = 561
Score = 45.2 bits (102), Expect = 0.002
Identities = 28/92 (30%), Positives = 46/92 (50%), Gaps = 4/92 (4%)
Frame = +1
Query: 466 VHDSPLTDTVR----KISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLA 633
V + P + VR +++ EL D V+ A +L LG+++G RVL+ +P E ++ LA
Sbjct: 41 VAEDPEKEAVRGPGGRLTRRELADAVAGAAARLAGLGITRGDRVLVQLPNDLELVVLPLA 100
Query: 634 TNRIGAIHSVVFGGFAARELRTRIEHAEPTVI 729
R+GA + REL + PT +
Sbjct: 101 LMRLGAHPVMAVPTLRRRELLAVVAATRPTAV 132
>UniRef50_Q3WHP4 Cluster: AMP-dependent synthetase and ligase; n=1;
Frankia sp. EAN1pec|Rep: AMP-dependent synthetase and
ligase - Frankia sp. EAN1pec
Length = 541
Score = 45.2 bits (102), Expect = 0.002
Identities = 28/85 (32%), Positives = 42/85 (49%)
Frame = +1
Query: 487 DTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVV 666
D ++SY +L D+V RLA L LG+ +G RV++++P E I + A +G I V
Sbjct: 52 DRDTRLSYRQLTDEVLRLAAGLQDLGLGRGDRVVVHLPNTYEYIAFVFALWELGVIPVVA 111
Query: 667 FGGFAARELRTRIEHAEPTVIIXAS 741
E+ IE AE I +
Sbjct: 112 PIAHRRAEIEHFIEIAEARTYITVA 136
>UniRef50_Q140M1 Cluster: Putative long chain fatty acid CoA ligase;
n=1; Burkholderia xenovorans LB400|Rep: Putative long
chain fatty acid CoA ligase - Burkholderia xenovorans
(strain LB400)
Length = 543
Score = 45.2 bits (102), Expect = 0.002
Identities = 23/77 (29%), Positives = 41/77 (53%)
Frame = +1
Query: 502 ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFA 681
ISY ++K+ V R+A L G+ +G V ++MP +P LA +IGAI +
Sbjct: 42 ISYQQMKEHVDRVARALLASGIERGDVVAVWMPNLPHFAFIELACAKIGAIIGAINTRSK 101
Query: 682 ARELRTRIEHAEPTVII 732
E+ ++H+E +++
Sbjct: 102 VFEVEHFMKHSEAKLLV 118
>UniRef50_A6GK66 Cluster: Non-ribosomal peptide synthetase; n=1;
Plesiocystis pacifica SIR-1|Rep: Non-ribosomal peptide
synthetase - Plesiocystis pacifica SIR-1
Length = 3382
Score = 45.2 bits (102), Expect = 0.002
Identities = 27/82 (32%), Positives = 42/82 (51%)
Frame = +1
Query: 496 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGG 675
R++SY +L+ +V LA +L LGV++G RV + E ++A LA N GA + +
Sbjct: 1475 RRLSYAQLRGRVVELAHRLVALGVARGDRVAVVARKGWEQVVAALAVNVAGAAYVPIDPT 1534
Query: 676 FAARELRTRIEHAEPTVIIXAS 741
A L +E E V + S
Sbjct: 1535 MPAARLGHIVEFTEARVALTQS 1556
>UniRef50_A4PHL4 Cluster: Non ribosomal peptide synthetase for
virginiamycin S; n=3; Actinomycetales|Rep: Non ribosomal
peptide synthetase for virginiamycin S - Streptomyces
virginiae
Length = 2671
Score = 45.2 bits (102), Expect = 0.002
Identities = 24/87 (27%), Positives = 45/87 (51%)
Frame = +1
Query: 481 LTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHS 660
+ D R+++Y EL + +RLA LT G V + +P + ++A+LA + GA +
Sbjct: 533 VVDGHRQLTYRELDARANRLAHLLTARGAGPERTVALALPRSADLVVALLAVVKTGAAYL 592
Query: 661 VVFGGFAARELRTRIEHAEPTVIIXAS 741
+ + A L + + A P+VI+ +
Sbjct: 593 PLDPDYPAERLASMLADAGPSVIVATA 619
>UniRef50_A3RXA3 Cluster: AMP-(Fatty)acid ligases; n=6;
Burkholderiales|Rep: AMP-(Fatty)acid ligases - Ralstonia
solanacearum UW551
Length = 563
Score = 45.2 bits (102), Expect = 0.002
Identities = 26/82 (31%), Positives = 43/82 (52%)
Frame = +1
Query: 496 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGG 675
R I + EL +RLA + LGV++G RV +++ P+ I+A LA ++GAI
Sbjct: 40 RTICWRELDQLSTRLAVQFQRLGVARGDRVALFLQNCPQGILAHLAAAKLGAIAVPCLPL 99
Query: 676 FAARELRTRIEHAEPTVIIXAS 741
ELR ++ ++I A+
Sbjct: 100 SRQHELRDQLTDCGARILIAAA 121
>UniRef50_A1RCH2 Cluster: Putative coenzyme A ligase; n=1;
Arthrobacter aurescens TC1|Rep: Putative coenzyme A
ligase - Arthrobacter aurescens (strain TC1)
Length = 547
Score = 45.2 bits (102), Expect = 0.002
Identities = 25/77 (32%), Positives = 38/77 (49%)
Frame = +1
Query: 502 ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFA 681
++Y E D+V A GV G RVL+ M + ++ LA NRIGAI+ G
Sbjct: 41 LTYQEAHDRVDSFAAGFQRRGVHAGDRVLLVMDSSVDHVVTWLALNRIGAINVPANPGLT 100
Query: 682 ARELRTRIEHAEPTVII 732
L I+ +P++I+
Sbjct: 101 PFLLSRAIQMVDPSIIV 117
>UniRef50_Q5TF43 Cluster: Acyl-CoA synthetase short-chain family
member 1; n=7; Tetrapoda|Rep: Acyl-CoA synthetase
short-chain family member 1 - Homo sapiens (Human)
Length = 153
Score = 45.2 bits (102), Expect = 0.002
Identities = 25/88 (28%), Positives = 44/88 (50%), Gaps = 2/88 (2%)
Frame = +1
Query: 256 YEKAQQRSLNDPEGFWGEVGSE-LEWTKPWDRVLD-DSNAPFTKWWVGGEMSVCYNAVDR 429
Y ++ +P FWG + + L W P+ V D D + W++GG+++V N +D+
Sbjct: 58 YPALSAQAAREPAAFWGPLARDTLVWDTPYHTVWDCDFSTGKIGWFLGGQLNVSVNCLDQ 117
Query: 430 HVVNGRGEQFALVHDSPLTDTVRKISYN 513
H V E AL+ + T +I+Y+
Sbjct: 118 H-VRKSPESVALIWERDEPGTEVRITYS 144
>UniRef50_Q9HEI8 Cluster: Related to acetoacetyl-CoA synthetase;
n=14; Pezizomycotina|Rep: Related to acetoacetyl-CoA
synthetase - Neurospora crassa
Length = 781
Score = 45.2 bits (102), Expect = 0.002
Identities = 41/174 (23%), Positives = 72/174 (41%), Gaps = 16/174 (9%)
Frame = +1
Query: 256 YEKAQQRSLNDPEGFWGEVGSELEWTKP--WDRVLDDSNAPFTK---WWVGGEMSVCYNA 420
+ + + SL + FW +V E + + RV+D+S AP W+ G ++S N
Sbjct: 112 FSELHEYSLRNRSQFWADVWEEANYIHEGTYSRVVDES-APIDAVPIWFEGVKLSYAENV 170
Query: 421 VD-----------RHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGV 567
+ R V ++ A+ R +Y EL+++ RLA + GV
Sbjct: 171 LYSRPKGSSSSQIRSTVGKEDDKVAVTEVREGASETRDATYGELRERAGRLAAAMKARGV 230
Query: 568 SKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVI 729
KG V+I + ++ LAT+ +GAI S + + R P ++
Sbjct: 231 KKGDIVVIVGSNSIDTLLVWLATSWLGAIFSSSSTDMGTKGILQRTVQVNPKLL 284
>UniRef50_Q8YTR4 Cluster: All2649 protein; n=3; Nostocaceae|Rep:
All2649 protein - Anabaena sp. (strain PCC 7120)
Length = 1583
Score = 44.8 bits (101), Expect = 0.002
Identities = 26/83 (31%), Positives = 42/83 (50%)
Frame = +1
Query: 502 ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFA 681
++Y EL +V++LA L LGV + V IY+ PE IIA+LA + G + +
Sbjct: 539 LTYQELNSKVNQLAHHLQKLGVGCESLVGIYLERSPELIIALLAVLKAGGAYIPLDNKLP 598
Query: 682 ARELRTRIEHAEPTVIIXASCGV 750
L + A+P +I+ + V
Sbjct: 599 PERLAYMLGDAQPRIILTMAASV 621
>UniRef50_Q62C03 Cluster: Nonribosomal peptide synthetase DhbF;
n=18; Burkholderia|Rep: Nonribosomal peptide synthetase
DhbF - Burkholderia mallei (Pseudomonas mallei)
Length = 1082
Score = 44.8 bits (101), Expect = 0.002
Identities = 26/84 (30%), Positives = 41/84 (48%)
Frame = +1
Query: 481 LTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHS 660
L D R+I+Y EL + +RLA L GV A V ++MP E ++ MLA + G +
Sbjct: 494 LVDRGRRITYGELNARANRLAHVLIEAGVGPEALVGLHMPRSAELVVGMLAILKAGGAYV 553
Query: 661 VVFGGFAARELRTRIEHAEPTVII 732
+ + A + + A P + I
Sbjct: 554 PLDPAYPASRIEFMVADARPMLSI 577
>UniRef50_Q5P655 Cluster: Cyclohexanecarboxylate-CoA ligase; n=5;
Proteobacteria|Rep: Cyclohexanecarboxylate-CoA ligase -
Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum
(strain EbN1))
Length = 549
Score = 44.8 bits (101), Expect = 0.002
Identities = 30/81 (37%), Positives = 39/81 (48%)
Frame = +1
Query: 499 KISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGF 678
++SY EL +V R+A L LGV +G V +P E + LA RIGA + V F
Sbjct: 55 RLSYRELDCRVDRIARGLAALGVGRGDVVSFQLPNRWEFVALALACARIGAAANPVMPIF 114
Query: 679 AARELRTRIEHAEPTVIIXAS 741
EL + AE V I S
Sbjct: 115 RQHELTYMLNFAESKVFIVPS 135
>UniRef50_Q2SFM4 Cluster: Non-ribosomal peptide synthetase modules and
related protein; n=2; cellular organisms|Rep:
Non-ribosomal peptide synthetase modules and related
protein - Hahella chejuensis (strain KCTC 2396)
Length = 2853
Score = 44.8 bits (101), Expect = 0.002
Identities = 26/87 (29%), Positives = 42/87 (48%)
Frame = +1
Query: 481 LTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHS 660
L D ++SY +++ Q LA K+ GVS G V + +P IA+ A GA +
Sbjct: 2007 LEDETHRLSYRQMRAQALALAQKMRRAGVSTGDIVAVALPRSARLSIALTAVLESGAAYL 2066
Query: 661 VVFGGFAARELRTRIEHAEPTVIIXAS 741
+ G+ L + +A P +II +S
Sbjct: 2067 PLDTGYPDERLGYMVRNAAPRLIITSS 2093
>UniRef50_Q5DIU0 Cluster: PvdI; n=3; cellular organisms|Rep: PvdI -
Pseudomonas aeruginosa
Length = 3680
Score = 44.8 bits (101), Expect = 0.002
Identities = 25/79 (31%), Positives = 40/79 (50%)
Frame = +1
Query: 496 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGG 675
+++SY EL Q +RLA +L LGV RV I M E ++A LA + G + +
Sbjct: 3094 QRLSYGELDSQANRLAQRLVELGVGPEVRVAIAMRRSAEIMVAFLAVLKAGGAYVPLDIA 3153
Query: 676 FAARELRTRIEHAEPTVII 732
+ A LR +E +++
Sbjct: 3154 YPAERLRYMLEDCGAALVL 3172
>UniRef50_Q13I22 Cluster: Putative AMP-dependent synthetase and
ligase; n=1; Burkholderia xenovorans LB400|Rep: Putative
AMP-dependent synthetase and ligase - Burkholderia
xenovorans (strain LB400)
Length = 559
Score = 44.8 bits (101), Expect = 0.002
Identities = 30/96 (31%), Positives = 48/96 (50%)
Frame = +1
Query: 427 RHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLV 606
R +V G + ALV +++Y +L ++V LA +L GV +G +V + M
Sbjct: 48 RELVANHGNREALVGQG------ERMTYQQLGERVEALAARLIRTGVKRGEKVGVLMGNR 101
Query: 607 PEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHA 714
PE +I+ LA IGA+ + AREL + H+
Sbjct: 102 PEWVISALAITSIGAVLVSLNSWATARELAYLLSHS 137
>UniRef50_Q0X0B9 Cluster: Putative non-ribosomal peptide synthetase;
n=1; Streptomyces lasaliensis|Rep: Putative non-ribosomal
peptide synthetase - Streptomyces lasaliensis
Length = 2609
Score = 44.8 bits (101), Expect = 0.002
Identities = 21/78 (26%), Positives = 44/78 (56%)
Frame = +1
Query: 499 KISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGF 678
+++Y EL+++ RLA L GV +RV++ +P + ++A+LA + G + V +
Sbjct: 2057 RLTYRELEERSGRLAHWLAGRGVGPESRVVVLLPRSADLVVALLAVWKAGGTYVPVDPEY 2116
Query: 679 AARELRTRIEHAEPTVII 732
A +R +E + P +++
Sbjct: 2117 PAARVRAVVEDSAPVLVL 2134
Score = 42.7 bits (96), Expect = 0.009
Identities = 23/78 (29%), Positives = 39/78 (50%)
Frame = +1
Query: 505 SYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAA 684
+Y EL ++ RLA LT G V + +P PE ++A++A R GA + V + A
Sbjct: 496 TYRELAERSGRLARLLTERGAGPERCVAVAVPRSPELVVALIAVLRAGAAYLPVDPDYPA 555
Query: 685 RELRTRIEHAEPTVIIXA 738
+ + A P +++ A
Sbjct: 556 ARVAFMLADARPALLLTA 573
>UniRef50_O68487 Cluster: Actinomycin synthetase II; n=1; Streptomyces
anulatus|Rep: Actinomycin synthetase II - Streptomyces
chrysomallus
Length = 2611
Score = 44.8 bits (101), Expect = 0.002
Identities = 25/95 (26%), Positives = 47/95 (49%), Gaps = 1/95 (1%)
Frame = +1
Query: 451 EQFALVHDSP-LTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAM 627
+Q L D+P L +SY+EL + + LA +LTT G+ G V + + P+ + +
Sbjct: 1540 QQVTLTPDAPALVSDGATLSYSELNTRANHLAHQLTTRGIRPGDAVAVLLQRSPDTVTTV 1599
Query: 628 LATNRIGAIHSVVFGGFAARELRTRIEHAEPTVII 732
LA + GA + + + A +R ++ ++I
Sbjct: 1600 LALAKTGATYIPLDSRYPADRIRLVLDETRTKLLI 1634
Score = 41.5 bits (93), Expect = 0.021
Identities = 22/80 (27%), Positives = 42/80 (52%)
Frame = +1
Query: 502 ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFA 681
++Y EL ++ +RLA L GV V + +P + ++A+LA + GA + + +
Sbjct: 489 LTYRELDERANRLAHLLAAHGVGPERIVALALPRSVDLVVAVLAVLKAGAAYLPLDPEYP 548
Query: 682 ARELRTRIEHAEPTVIIXAS 741
A L + A+PT+I+ +
Sbjct: 549 ANRLAHMVTDAQPTLILTTT 568
>UniRef50_A1G2S7 Cluster: Amino acid adenylation domain; n=1;
Salinispora arenicola CNS205|Rep: Amino acid adenylation
domain - Salinispora arenicola CNS205
Length = 2350
Score = 44.8 bits (101), Expect = 0.002
Identities = 25/77 (32%), Positives = 40/77 (51%)
Frame = +1
Query: 502 ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFA 681
++Y EL +RLA +L LG G V +++ P+ ++ MLAT R GA + +
Sbjct: 1534 LTYAELDAAANRLAHRLRALGAGPGTLVGLFLTRSPDLVVGMLATLRAGAAFLPLDPAYP 1593
Query: 682 ARELRTRIEHAEPTVII 732
A LR I AE +++
Sbjct: 1594 AERLRYLITDAEVGLLL 1610
>UniRef50_Q9M0X9 Cluster: 4-coumarate--CoA ligase-like 7; n=1;
Arabidopsis thaliana|Rep: 4-coumarate--CoA ligase-like 7
- Arabidopsis thaliana (Mouse-ear cress)
Length = 544
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/86 (27%), Positives = 44/86 (51%)
Frame = +1
Query: 484 TDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSV 663
+DT +++++LK V+RLA LG+ K VLI+ P + + LA IG + +
Sbjct: 49 SDTGDSLTFSQLKSAVARLAHGFHRLGIRKNDVVLIFAPNSYQFPLCFLAVTAIGGVFTT 108
Query: 664 VFGGFAARELRTRIEHAEPTVIIXAS 741
+ E+ +I+ + P +II +
Sbjct: 109 ANPLYTVNEVSKQIKDSNPKIIISVN 134
>UniRef50_Q7W4Q6 Cluster: Putative fatty acid CoA ligase; n=3;
Bordetella|Rep: Putative fatty acid CoA ligase -
Bordetella parapertussis
Length = 543
Score = 44.4 bits (100), Expect = 0.003
Identities = 26/71 (36%), Positives = 38/71 (53%)
Frame = +1
Query: 481 LTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHS 660
L D R +++ L+ V LAG L LGV +G RV +++P + LA R+GA+
Sbjct: 36 LIDRDRPVTHAALRAGVLDLAGGLAALGVCRGERVALWLPNCAHWVTMFLACARLGALTL 95
Query: 661 VVFGGFAAREL 693
V F A+EL
Sbjct: 96 AVNTRFRAQEL 106
>UniRef50_Q5KZX6 Cluster: Hypothetical conserved protein; n=1;
Geobacillus kaustophilus|Rep: Hypothetical conserved
protein - Geobacillus kaustophilus
Length = 495
Score = 44.4 bits (100), Expect = 0.003
Identities = 24/89 (26%), Positives = 43/89 (48%)
Frame = +1
Query: 466 VHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRI 645
VH + LT S ++++ +V++ LT LG + RV +P + +LA NR+
Sbjct: 17 VHKTILTSQTGSYSLDDIRQEVNKYCSLLTQLGPVQRKRVAFMIPYASSFLSLLLAVNRL 76
Query: 646 GAIHSVVFGGFAARELRTRIEHAEPTVII 732
GA+ + + +L +E P VI+
Sbjct: 77 GAVAVPISPFLRSEDLSRLLEFINPHVIL 105
>UniRef50_A6UHL1 Cluster: AMP-dependent synthetase and ligase; n=2;
Sinorhizobium|Rep: AMP-dependent synthetase and ligase -
Sinorhizobium medicae WSM419
Length = 515
Score = 44.4 bits (100), Expect = 0.003
Identities = 28/79 (35%), Positives = 39/79 (49%)
Frame = +1
Query: 496 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGG 675
R++SY EL D +RLA L GV + RVL +M EA +A+ A + GA S +
Sbjct: 25 RRLSYAELDDLSTRLAAALAANGVKRNDRVLAFMDNCWEAAVAIFAILKAGATFSPINAS 84
Query: 676 FAARELRTRIEHAEPTVII 732
A +L I E I+
Sbjct: 85 TKADKLAYVIADCEAAAIL 103
>UniRef50_Q4PHX8 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 828
Score = 44.4 bits (100), Expect = 0.003
Identities = 24/86 (27%), Positives = 43/86 (50%)
Frame = +1
Query: 472 DSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGA 651
DS + K+++ EL+ +V+ LA +GV KG R+ I+A LA N +GA
Sbjct: 142 DSDVNAQAVKVTWGELRRRVALLAETFRRIGVKKGDRLAHVSANTSSPIVATLAANSVGA 201
Query: 652 IHSVVFGGFAARELRTRIEHAEPTVI 729
I+S++ + + R+ P ++
Sbjct: 202 IYSLIATDAGPQAIYGRLAQIRPKLL 227
>UniRef50_Q83MG9 Cluster: Probable crotonobetaine/carnitine-CoA
ligase; n=39; Bacteria|Rep: Probable
crotonobetaine/carnitine-CoA ligase - Shigella flexneri
Length = 517
Score = 44.4 bits (100), Expect = 0.003
Identities = 25/98 (25%), Positives = 49/98 (50%)
Frame = +1
Query: 448 GEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAM 627
G + AL+ +S V + SY EL +++R A TLG+ KG +V +++ PE I
Sbjct: 21 GHKTALICESS-GGVVNRYSYLELNQEINRTANLFYTLGIRKGNKVALHLDNCPEFIFCW 79
Query: 628 LATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXAS 741
+IGAI + E +++++ +++ ++
Sbjct: 80 FGLAKIGAIMVPINARLLREESEWILQNSQACLLVTSA 117
>UniRef50_UPI0000165EEF Cluster: acyl-CoA synthase; n=1; Deinococcus
radiodurans R1|Rep: acyl-CoA synthase - Deinococcus
radiodurans R1
Length = 593
Score = 44.0 bits (99), Expect = 0.004
Identities = 22/53 (41%), Positives = 32/53 (60%)
Frame = +1
Query: 496 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAI 654
R+++Y +L DQV RLAG L GV KG RV +++ P I A ++GA+
Sbjct: 63 RELTYGDLYDQVGRLAGHLAAQGVRKGDRVGLWLQNSPAWAIGAFAAWQLGAV 115
>UniRef50_Q9Z4X6 Cluster: CDA peptide synthetase I; n=4; cellular
organisms|Rep: CDA peptide synthetase I - Streptomyces
coelicolor
Length = 7463
Score = 44.0 bits (99), Expect = 0.004
Identities = 25/84 (29%), Positives = 42/84 (50%)
Frame = +1
Query: 481 LTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHS 660
LT +SY EL + +RLA LT G+ A V + +P E ++A+LA + GA +
Sbjct: 1688 LTFEGTSLSYAELNARANRLARLLTARGIGPDALVALALPRSAELVVALLAVVKSGAAYV 1747
Query: 661 VVFGGFAARELRTRIEHAEPTVII 732
+ G+ A L + + P ++
Sbjct: 1748 PLDPGYPADRLAHALSDSAPAALL 1771
Score = 39.1 bits (87), Expect = 0.11
Identities = 21/80 (26%), Positives = 38/80 (47%)
Frame = +1
Query: 502 ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFA 681
++Y EL ++ +RLA L G V + +P + +++ LA + GA + V
Sbjct: 2784 LTYGELNERANRLARALLARGAGPERFVAVALPRSADLVLSALAAFKAGAAYLPVDPAHP 2843
Query: 682 ARELRTRIEHAEPTVIIXAS 741
A + + A PT+I+ S
Sbjct: 2844 AERITHLVSDAAPTLIVTTS 2863
Score = 34.3 bits (75), Expect = 3.3
Identities = 21/77 (27%), Positives = 36/77 (46%)
Frame = +1
Query: 502 ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFA 681
+SY EL + +RLA L GV G V++ M P ++A LA + G + + +
Sbjct: 6381 VSYAELDLRTNRLARLLRQQGVRPGTPVVMLMERSPAHVVATLAIAKAGGAYVPLHDTYP 6440
Query: 682 ARELRTRIEHAEPTVII 732
+R + T+I+
Sbjct: 6441 LDRMRHVVADTAATLIL 6457
Score = 33.5 bits (73), Expect = 5.7
Identities = 20/79 (25%), Positives = 40/79 (50%)
Frame = +1
Query: 502 ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFA 681
++Y EL + ++LA L G+ V I + +A+I+MLA + GA + + +
Sbjct: 5343 LTYAELDRRANQLARHLLGEGLGAEDFVAIALAKSLDAVISMLAVLKTGAAYLPIDPDYP 5402
Query: 682 ARELRTRIEHAEPTVIIXA 738
A + ++ A+P + + A
Sbjct: 5403 AERITYMLDDAQPALTLTA 5421
>UniRef50_Q5P0J2 Cluster: 4-hydroxybenzoate CoA ligase; n=1;
Azoarcus sp. EbN1|Rep: 4-hydroxybenzoate CoA ligase -
Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum
(strain EbN1))
Length = 493
Score = 44.0 bits (99), Expect = 0.004
Identities = 24/77 (31%), Positives = 38/77 (49%)
Frame = +1
Query: 499 KISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGF 678
K+SY L+D+VSR AG TLG+ G RV+++ P + ++A L G + V
Sbjct: 24 KVSYAVLRDRVSRAAGAWKTLGLQPGNRVIVFAPDSVDWVVAYLGAIWAGGVAIGVNPRL 83
Query: 679 AARELRTRIEHAEPTVI 729
+ E + EP +
Sbjct: 84 SMNEFAPILNECEPRFV 100
>UniRef50_Q4ZVI2 Cluster: Amino acid adenylation; n=4;
Pseudomonas|Rep: Amino acid adenylation - Pseudomonas
syringae pv. syringae (strain B728a)
Length = 1370
Score = 44.0 bits (99), Expect = 0.004
Identities = 24/79 (30%), Positives = 41/79 (51%)
Frame = +1
Query: 496 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGG 675
R +SY++L Q +RLA L TLGV RV + + E +A+LA + G + +
Sbjct: 552 RSLSYSQLNTQANRLAHHLLTLGVGPDVRVAVCIERSLELPVALLAVLKAGGAYVPLDPD 611
Query: 676 FAARELRTRIEHAEPTVII 732
+ + LR ++ P V++
Sbjct: 612 YPSGRLRHILDDTSPVVLL 630
>UniRef50_Q333V5 Cluster: NRPS protein; n=2; Actinomycetales|Rep:
NRPS protein - Micromonospora sp. ML1
Length = 596
Score = 44.0 bits (99), Expect = 0.004
Identities = 23/79 (29%), Positives = 40/79 (50%)
Frame = +1
Query: 496 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGG 675
R +SY EL + +RLA L GV V + MP E ++ +LA + G + +
Sbjct: 26 RLVSYAELDARANRLARVLVERGVGPDTTVAVAMPKCDELMVVLLAVLKAGGAYLPLDPQ 85
Query: 676 FAARELRTRIEHAEPTVII 732
+ A+ L ++ A PT+++
Sbjct: 86 YPAKRLAYMVQDARPTLLV 104
>UniRef50_Q0SK68 Cluster: Non-ribosomal peptide synthetase; n=1;
Rhodococcus sp. RHA1|Rep: Non-ribosomal peptide
synthetase - Rhodococcus sp. (strain RHA1)
Length = 8871
Score = 44.0 bits (99), Expect = 0.004
Identities = 26/90 (28%), Positives = 44/90 (48%)
Frame = +1
Query: 472 DSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGA 651
+S LTDT ++Y L +V RLA L LG + V + +P + ++A+LA + GA
Sbjct: 5446 ESALTDTGETLTYAALGARVYRLARHLVELGAAPDTVVAVALPPSIDLVVALLAAQQAGA 5505
Query: 652 IHSVVFGGFAARELRTRIEHAEPTVIIXAS 741
+ + G A L + A P ++ +
Sbjct: 5506 GYLALDVGHPADRLDATMSDAAPVCLVSTT 5535
Score = 37.1 bits (82), Expect = 0.46
Identities = 21/75 (28%), Positives = 37/75 (49%)
Frame = +1
Query: 481 LTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHS 660
L D+ R +SY +L + +RLA L T G V + +P ++++A+ A + GA
Sbjct: 6991 LEDSGRAVSYRDLDEASNRLARLLITRGAGPERYVALAIPRSADSVLAVWAITKTGAAFV 7050
Query: 661 VVFGGFAARELRTRI 705
+ G+ A + I
Sbjct: 7051 PIDPGYPAARITDMI 7065
>UniRef50_Q0S5F4 Cluster: Non-ribosomal peptide synthetase; n=1;
Rhodococcus sp. RHA1|Rep: Non-ribosomal peptide
synthetase - Rhodococcus sp. (strain RHA1)
Length = 8344
Score = 44.0 bits (99), Expect = 0.004
Identities = 25/83 (30%), Positives = 41/83 (49%)
Frame = +1
Query: 502 ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFA 681
+SY +L +RLA +L G+ V + +P PE+++A+ A R GA V G+
Sbjct: 503 LSYGQLDVWSNRLAHRLIERGIGPEDVVAVMLPRSPESVVAVWAVARSGAAFLPVDPGYP 562
Query: 682 ARELRTRIEHAEPTVIIXASCGV 750
A + + +E TV + A V
Sbjct: 563 AERIAFMLADSETTVALAADASV 585
Score = 42.7 bits (96), Expect = 0.009
Identities = 22/77 (28%), Positives = 40/77 (51%)
Frame = +1
Query: 502 ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFA 681
++Y +L + + +A L GV V + +P + ++AMLA R GA + + +
Sbjct: 4569 VTYGDLDHRSAEMAESLRASGVGAEDLVALVLPRSVDLVVAMLAVIRAGAAYLPIDVDYP 4628
Query: 682 ARELRTRIEHAEPTVII 732
A +R ++ A PTV+I
Sbjct: 4629 AERIRYLLDDAAPTVVI 4645
Score = 39.5 bits (88), Expect = 0.086
Identities = 23/61 (37%), Positives = 31/61 (50%), Gaps = 1/61 (1%)
Frame = +1
Query: 472 DSP-LTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIG 648
D P LTD R +SY EL + + AG+L G G V I MP + ++ + A R G
Sbjct: 6567 DRPALTDGTRTLSYRELAEASQQRAGQLRDAGAGPGTVVEICMPRSIDFVVELWAVTRTG 6626
Query: 649 A 651
A
Sbjct: 6627 A 6627
Score = 39.1 bits (87), Expect = 0.11
Identities = 22/80 (27%), Positives = 39/80 (48%)
Frame = +1
Query: 499 KISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGF 678
+++Y EL + +RLA +L G+ V + +P E+I+A+ A R GA V G+
Sbjct: 2522 EVTYRELDARANRLARRLIARGIGPEDLVALMLPRSVESIVAVWAVTRSGAAFLPVDPGY 2581
Query: 679 AARELRTRIEHAEPTVIIXA 738
A + + + V + A
Sbjct: 2582 PAERIAFMLHDSGAAVALAA 2601
Score = 37.5 bits (83), Expect = 0.35
Identities = 19/61 (31%), Positives = 34/61 (55%)
Frame = +1
Query: 469 HDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIG 648
HD + +++Y EL ++ +RLA KL LG+ V + +P +++ A+ A R+G
Sbjct: 3534 HDVAVRCGDDELTYRELDERANRLARKLIRLGIGPEDAVALLLPRSIDSVTAVWAVARVG 3593
Query: 649 A 651
A
Sbjct: 3594 A 3594
>UniRef50_A5ERA9 Cluster: Arthrofactin synthetase/syringopeptin
synthetase C-related non- ribosomal peptide synthetase
module; n=8; Proteobacteria|Rep: Arthrofactin
synthetase/syringopeptin synthetase C-related non-
ribosomal peptide synthetase module - Bradyrhizobium sp.
(strain BTAi1 / ATCC BAA-1182)
Length = 8646
Score = 44.0 bits (99), Expect = 0.004
Identities = 24/79 (30%), Positives = 39/79 (49%)
Frame = +1
Query: 496 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGG 675
R++SY EL Q +RLA L LGV RV I + PE I+ +LA + G + +
Sbjct: 521 RRLSYAELNTQANRLAHHLRKLGVKPDDRVAICIERSPEMIVGLLAILKSGGAYVPLDPA 580
Query: 676 FAARELRTRIEHAEPTVII 732
+ L ++ + P ++
Sbjct: 581 YPPERLAFMVQDSAPAALL 599
Score = 44.0 bits (99), Expect = 0.004
Identities = 24/79 (30%), Positives = 39/79 (49%)
Frame = +1
Query: 496 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGG 675
R++SY EL Q +RLA L LGV RV I + PE I+ +LA + G + +
Sbjct: 6978 RRLSYAELNTQANRLAHHLRKLGVKPDDRVAICIARSPEMIVGLLAILKAGGAYVPLDPA 7037
Query: 676 FAARELRTRIEHAEPTVII 732
+ L ++ + P ++
Sbjct: 7038 YPPERLAFMLQDSAPVALL 7056
Score = 43.6 bits (98), Expect = 0.005
Identities = 24/79 (30%), Positives = 38/79 (48%)
Frame = +1
Query: 496 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGG 675
R++SY EL Q +RLA L LGV RV I + PE I+ +LA + G + +
Sbjct: 1601 RRLSYAELNTQANRLAHHLRKLGVKPDDRVAICIARSPEMIVGLLAILKAGGAYVPLDPA 1660
Query: 676 FAARELRTRIEHAEPTVII 732
+ L + + P ++
Sbjct: 1661 YPPERLAFMVRDSAPVALL 1679
Score = 43.2 bits (97), Expect = 0.007
Identities = 24/79 (30%), Positives = 38/79 (48%)
Frame = +1
Query: 496 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGG 675
R++SY EL Q +RLA L LGV RV I + PE I+ +LA + G + +
Sbjct: 2691 RRLSYAELNTQANRLAHHLRGLGVKPDDRVAICIARSPEMIVGLLAILKAGGAYVPLDPA 2750
Query: 676 FAARELRTRIEHAEPTVII 732
+ L + + P ++
Sbjct: 2751 YPPERLAFMVRDSAPAALL 2769
Score = 43.2 bits (97), Expect = 0.007
Identities = 24/79 (30%), Positives = 38/79 (48%)
Frame = +1
Query: 496 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGG 675
R++SY EL Q +RLA L LGV RV I + PE I+ +LA + G + +
Sbjct: 5923 RRLSYAELNTQANRLAHHLRGLGVKPDDRVAICIARSPEMIVGLLAILKAGGAYVPLDPA 5982
Query: 676 FAARELRTRIEHAEPTVII 732
+ L + + P ++
Sbjct: 5983 YPPERLAFMVRDSAPAALL 6001
Score = 43.2 bits (97), Expect = 0.007
Identities = 24/79 (30%), Positives = 38/79 (48%)
Frame = +1
Query: 496 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGG 675
R++SY EL Q +RLA L LGV RV I + PE I+ +LA + G + +
Sbjct: 8068 RRLSYAELNTQANRLAHHLRKLGVRPDDRVAICIARSPEMIVGLLAILKAGGAYVPLDPA 8127
Query: 676 FAARELRTRIEHAEPTVII 732
+ L + + P ++
Sbjct: 8128 YPPERLAFMVRDSAPVALL 8146
Score = 40.7 bits (91), Expect = 0.037
Identities = 32/111 (28%), Positives = 50/111 (45%)
Frame = +1
Query: 406 VCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARV 585
VC + + + A+VHD R++SY EL + +RLA L LGV RV
Sbjct: 3747 VCVHELFEAQAERTPDAVAVVHDK------RRLSYAELNTEANRLAHHLRKLGVRPDDRV 3800
Query: 586 LIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELRTRIEHAEPTVIIXA 738
I + E + A LA + GA + + A L I+ E ++++ A
Sbjct: 3801 AICIERSIELVAAELAILKCGAAYVPLDRDVPAERLAFMIKDCEASLVLMA 3851
Score = 38.7 bits (86), Expect = 0.15
Identities = 26/80 (32%), Positives = 39/80 (48%)
Frame = +1
Query: 499 KISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGF 678
++SY EL Q +RLA L LGV RV I + E + A LA + GA + +
Sbjct: 4848 RLSYAELNTQANRLAHHLRKLGVRPDDRVAICIERSIELVAAELAILKCGAAYVPLDRDV 4907
Query: 679 AARELRTRIEHAEPTVIIXA 738
A L I+ E ++++ A
Sbjct: 4908 PAERLAFMIKDCEASLVLMA 4927
>UniRef50_A5A9U3 Cluster: Mps2 protein; n=2; Mycobacterium|Rep: Mps2
protein - Mycobacterium abscessus
Length = 2581
Score = 44.0 bits (99), Expect = 0.004
Identities = 27/87 (31%), Positives = 40/87 (45%)
Frame = +1
Query: 481 LTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHS 660
LT R +Y EL + +RLA L+ G + G V + MP EAIIA+LA + GA +
Sbjct: 1570 LTFEGRSTTYGELDEAANRLANLLSVYGAAPGESVALLMPRSDEAIIAILAILKTGASYL 1629
Query: 661 VVFGGFAARELRTRIEHAEPTVIIXAS 741
+ L + A P + +
Sbjct: 1630 PIDPSVPDTRLEFMLSDAVPIAAVTTA 1656
Score = 34.3 bits (75), Expect = 3.3
Identities = 21/82 (25%), Positives = 36/82 (43%)
Frame = +1
Query: 496 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGG 675
R +Y EL +R+A L G G V + +P EAII +LA + GA + +
Sbjct: 64 RSWTYRELDQITNRIAHLLAGNGAGPGEVVGLLVPRSGEAIIGLLAILKTGAAYLPIDPA 123
Query: 676 FAARELRTRIEHAEPTVIIXAS 741
++ + A P ++ +
Sbjct: 124 HPDERIKFMVSDAGPVAVLTTA 145
>UniRef50_A4FF93 Cluster: AMP-dependent synthetase and ligase; n=2;
Actinomycetales|Rep: AMP-dependent synthetase and ligase
- Saccharopolyspora erythraea (strain NRRL 23338)
Length = 522
Score = 44.0 bits (99), Expect = 0.004
Identities = 27/76 (35%), Positives = 39/76 (51%)
Frame = +1
Query: 505 SYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAA 684
+Y EL D+VSRL G L + GV G R+ + EA+ LA+ R+GAI V A
Sbjct: 44 TYRELDDRVSRLVGALRSRGVRPGDRIAVMCLNGIEAVETYLASVRLGAICVPVNFRLVA 103
Query: 685 RELRTRIEHAEPTVII 732
E+ + EP ++
Sbjct: 104 DEVAYLLGDCEPAAVV 119
>UniRef50_A3Z2Q3 Cluster: Acyl-CoA synthase; n=1; Synechococcus sp.
WH 5701|Rep: Acyl-CoA synthase - Synechococcus sp. WH
5701
Length = 321
Score = 44.0 bits (99), Expect = 0.004
Identities = 22/51 (43%), Positives = 30/51 (58%)
Frame = +1
Query: 502 ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAI 654
I+Y L ++V LAG L GV KG RVL+YM P+ +I+ A R A+
Sbjct: 48 ITYRRLNEEVETLAGYLQAQGVKKGDRVLLYMQNSPQYVISYYAILRADAV 98
>UniRef50_A7SNY7 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 567
Score = 44.0 bits (99), Expect = 0.004
Identities = 25/86 (29%), Positives = 41/86 (47%)
Frame = +1
Query: 397 EMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKG 576
E + +D H ++ + D + + +++ E +DQ LA KLT LG+ +G
Sbjct: 17 EHRTLFQLLDHHASKFPNKEAIIYRDE--NNNRKSLTFQEYRDQSRVLAAKLTELGLRRG 74
Query: 577 ARVLIYMPLVPEAIIAMLATNRIGAI 654
VL +P E I +A RIGA+
Sbjct: 75 HLVLALLPSEMEFAIVQMALGRIGAV 100
>UniRef50_Q2W0K6 Cluster: Acyl-coenzyme A synthetase/AMP-(Fatty)
acid ligase; n=4; Magnetospirillum|Rep: Acyl-coenzyme A
synthetase/AMP-(Fatty) acid ligase - Magnetospirillum
magneticum (strain AMB-1 / ATCC 700264)
Length = 549
Score = 43.6 bits (98), Expect = 0.005
Identities = 24/93 (25%), Positives = 51/93 (54%), Gaps = 1/93 (1%)
Frame = +1
Query: 379 KWWVGGEMSVCYNAVDRHVVNGR-GEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLT 555
+W + ++ ++ DR + G G + AL+ ++ V + +++ L+ +RLA L
Sbjct: 16 RWKIPERYNLAFDVCDRQTMAGADGHRTALIVEAA-DGGVERHTFHMLRLLSNRLANGLA 74
Query: 556 TLGVSKGARVLIYMPLVPEAIIAMLATNRIGAI 654
+G++ G RV + +P EA + +LA ++GA+
Sbjct: 75 AMGIAPGDRVAMALPAGLEAAVTLLAVTKMGAV 107
>UniRef50_Q9L8H4 Cluster: Actinomycin synthetase III; n=1;
Streptomyces anulatus|Rep: Actinomycin synthetase III -
Streptomyces chrysomallus
Length = 4247
Score = 43.6 bits (98), Expect = 0.005
Identities = 25/95 (26%), Positives = 46/95 (48%), Gaps = 1/95 (1%)
Frame = +1
Query: 451 EQFALVHDSP-LTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAM 627
+Q L D+P L +SY+EL + + LA +LTT G+ G V + + P+ + +
Sbjct: 3004 QQVTLTPDAPALVSDGATLSYSELNTRANHLAHQLTTRGIRPGDAVAVLLQRSPDTVTTV 3063
Query: 628 LATNRIGAIHSVVFGGFAARELRTRIEHAEPTVII 732
LA + GA + + + A R ++ ++I
Sbjct: 3064 LALAKTGATYIPLDSRYPADRYRLVLDETRTKLLI 3098
Score = 40.3 bits (90), Expect = 0.049
Identities = 21/80 (26%), Positives = 41/80 (51%)
Frame = +1
Query: 502 ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFA 681
+ Y EL ++ +RLA L GV V + +P + ++A+LA + GA + + +
Sbjct: 484 LRYRELDERANRLAHLLAAHGVGPERIVALALPRSVDLVVAVLAVLKAGAAYLPLDPEYP 543
Query: 682 ARELRTRIEHAEPTVIIXAS 741
A L + A+PT+++ +
Sbjct: 544 ANRLAHMVTDAQPTLVLTTT 563
>UniRef50_Q3L908 Cluster: Putative fatty-acid--CoA ligase; n=1;
Rhodococcus erythropolis PR4|Rep: Putative
fatty-acid--CoA ligase - Rhodococcus erythropolis
(strain PR4)
Length = 511
Score = 43.6 bits (98), Expect = 0.005
Identities = 24/76 (31%), Positives = 41/76 (53%)
Frame = +1
Query: 505 SYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAA 684
SY +L ++++ A L +LGV KG RV + P ++A+ ++GAI S A
Sbjct: 29 SYGQLDREINQYANALLSLGVQKGDRVAVLSPNSDRFLLALYGAFKVGAIVSPFNPRSTA 88
Query: 685 RELRTRIEHAEPTVII 732
REL +E + +V++
Sbjct: 89 RELAYLLEDSGASVLL 104
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 792,755,130
Number of Sequences: 1657284
Number of extensions: 16940959
Number of successful extensions: 50241
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 47770
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 50084
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 61734884250
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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