Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P09_F_B13
(863 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_O15118 Cluster: Niemann-Pick C1 protein precursor; n=39... 157 4e-37
UniRef50_A7S0G1 Cluster: Predicted protein; n=1; Nematostella ve... 151 2e-35
UniRef50_UPI0000586B35 Cluster: PREDICTED: similar to Niemann-Pi... 144 2e-33
UniRef50_UPI000069E05B Cluster: Niemann-Pick C1-like protein 1 p... 126 7e-28
UniRef50_UPI00015B5F3E Cluster: PREDICTED: similar to CG5722-PA;... 120 5e-26
UniRef50_Q4RWY5 Cluster: Chromosome 15 SCAF14981, whole genome s... 109 1e-22
UniRef50_UPI000065FF0C Cluster: Niemann-Pick C1-like protein 1 p... 106 8e-22
UniRef50_UPI0000DB7411 Cluster: PREDICTED: similar to Niemann-Pi... 104 3e-21
UniRef50_Q9SVF0 Cluster: Putative uncharacterized protein F22I13... 102 1e-20
UniRef50_Q01KH5 Cluster: H0409D10.4 protein; n=5; Eukaryota|Rep:... 102 1e-20
UniRef50_Q9UHC9 Cluster: Niemann-Pick C1-like protein 1 precurso... 102 1e-20
UniRef50_Q4T749 Cluster: Chromosome undetermined SCAF8317, whole... 99 2e-19
UniRef50_Q9SHN9 Cluster: F7F22.1; n=2; Arabidopsis thaliana|Rep:... 96 9e-19
UniRef50_Q9VRC9 Cluster: CG12092-PA; n=4; Diptera|Rep: CG12092-P... 94 4e-18
UniRef50_UPI0000E48444 Cluster: PREDICTED: similar to Niemann Pi... 93 6e-18
UniRef50_A7QPC0 Cluster: Chromosome chr18 scaffold_137, whole ge... 93 8e-18
UniRef50_A5APM6 Cluster: Putative uncharacterized protein; n=1; ... 93 8e-18
UniRef50_Q5KGS9 Cluster: Vacuolar membrane protein, putative; n=... 89 1e-16
UniRef50_A2QWF9 Cluster: Remark: Niemann-Pick C precursor; n=16;... 88 3e-16
UniRef50_Q12200 Cluster: Niemann-pick type C-related protein 1 p... 86 1e-15
UniRef50_Q19127 Cluster: Niemann-Pick C1 protein homolog 1 precu... 85 3e-15
UniRef50_Q6QVL7 Cluster: NPC1 precursor; n=1; Ornithodoros mouba... 83 7e-15
UniRef50_Q6CBA1 Cluster: Similar to tr|Q12200 Saccharomyces cere... 74 4e-12
UniRef50_A3GGU6 Cluster: Predicted protein; n=5; Saccharomycetal... 73 7e-12
UniRef50_Q4PE83 Cluster: Putative uncharacterized protein; n=1; ... 71 3e-11
UniRef50_UPI0000D573E9 Cluster: PREDICTED: similar to CG5722-PA;... 69 2e-10
UniRef50_P34389 Cluster: Niemann-Pick C1 protein homolog 2 precu... 69 2e-10
UniRef50_Q54ED0 Cluster: Putative transmembrane protein; n=1; Di... 61 4e-08
UniRef50_Q55BN1 Cluster: NPC1 protein; n=2; Dictyostelium discoi... 51 3e-05
UniRef50_A2XWG3 Cluster: Putative uncharacterized protein; n=2; ... 46 0.001
UniRef50_A4SA60 Cluster: Predicted protein; n=1; Ostreococcus lu... 34 4.0
UniRef50_UPI00015B5F5A Cluster: PREDICTED: similar to zinc finge... 33 7.1
UniRef50_Q5LFD2 Cluster: Putative DNA-binding protein; n=1; Bact... 33 7.1
UniRef50_Q22UV0 Cluster: Hypothetical repeat containing protein;... 33 7.1
UniRef50_Q9LC43 Cluster: TagG homolog; n=20; Staphylococcus|Rep:... 33 9.3
UniRef50_A2ECX9 Cluster: Putative uncharacterized protein; n=1; ... 33 9.3
>UniRef50_O15118 Cluster: Niemann-Pick C1 protein precursor; n=39;
Chordata|Rep: Niemann-Pick C1 protein precursor - Homo
sapiens (Human)
Length = 1278
Score = 157 bits (380), Expect = 4e-37
Identities = 69/192 (35%), Positives = 107/192 (55%), Gaps = 6/192 (3%)
Frame = +1
Query: 301 CIWYGVCANSTEHKMVNCFYDGPAKPIEEKAMKIIEQYCPEIAKGGYS-CCNYEQLNQLK 477
C+WYG C + K NC Y GP KP+ + ++++ CP G S CC+ QL LK
Sbjct: 25 CVWYGECGIAYGDKRYNCEYSGPPKPLPKDGYDLVQELCPGFFFGNVSLCCDVRQLQTLK 84
Query: 478 VNIALAENLLGRCPTCFQNFLKPICGMACAVDQSKYLKPVKTEQF-----NGTHRRISEI 642
N+ L L RCP+CF N L C + C+ QS++L TE + N T + E+
Sbjct: 85 DNLQLPLQFLSRCPSCFYNLLNLFCELTCSPRQSQFLNVTATEDYVDPVTNQTKTNVKEL 144
Query: 643 DYYLSKTFMDGIYNSCSEVKLTSTNERSIKVMCGQWGDACSAQRWFDNMGDASNYQVPFX 822
YY+ ++F + +YN+C +V+ S+N++++ ++CG+ DAC+A W + M + N Q PF
Sbjct: 145 QYYVGQSFANAMYNACRDVEAPSSNDKALGLLCGKDADACNATNWIEYMFNKDNGQAPFT 204
Query: 823 INYKATDVPVDG 858
I +D PV G
Sbjct: 205 ITPVFSDFPVHG 216
>UniRef50_A7S0G1 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 1277
Score = 151 bits (367), Expect = 2e-35
Identities = 67/179 (37%), Positives = 99/179 (55%), Gaps = 2/179 (1%)
Frame = +1
Query: 301 CIWYGVCANSTEHKMVNCFYDGPAKPIEE-KAMKIIEQYCPEIAKGGYSCCNYEQLNQLK 477
C+WYG C + +NC Y+ PAK + + KAM I++ CP+IA+GG +CC+ QL L
Sbjct: 1 CVWYGQCTKPGQTPALNCLYNEPAKELNDTKAMNILKNLCPKIAQGGKTCCDLRQLEALD 60
Query: 478 VNIALAENLLGRCPTCFQNFLKPICGMACAVDQSKYLKPVKTEQFNG-THRRISEIDYYL 654
N+ RCP C+QN L C C+ DQS ++ P F T I+ I+YY+
Sbjct: 61 SNLNTLRQFTSRCPACWQNMLDMYCESTCSPDQSLFMDPTSVVGFPPYTPYMINTINYYI 120
Query: 655 SKTFMDGIYNSCSEVKLTSTNERSIKVMCGQWGDACSAQRWFDNMGDASNYQVPFXINY 831
+ D ++ SC +V NE+ + ++CGQ + CS Q+ + MG SN Q PF I+Y
Sbjct: 121 APEHKDQLFKSCKDVIFPGNNEKILNLLCGQSAETCSPQKLLEYMGSTSNGQAPFDIHY 179
>UniRef50_UPI0000586B35 Cluster: PREDICTED: similar to Niemann-Pick
C disease protein isoform 1; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to Niemann-Pick C
disease protein isoform 1 - Strongylocentrotus
purpuratus
Length = 1332
Score = 144 bits (350), Expect = 2e-33
Identities = 67/213 (31%), Positives = 113/213 (53%), Gaps = 20/213 (9%)
Frame = +1
Query: 271 IPSALAEDGHCIWYGVCA-NSTEHKMVNCFYDGPAKPIEEKAMKIIEQYCPEIAKGGYS- 444
+ + + ++G+C+WY C ++ HK +NC Y+ PAK ++ K + ++ CPE+ S
Sbjct: 28 VAAYIHKEGYCMWYDQCGTDAVTHKSLNCLYNKPAKVLDTKGLDTLKTLCPEMVAANESE 87
Query: 445 ---CCNYEQLNQLKVNIALAENLLGRCPTCFQNFLKPICGMACAVDQSKYLKPVKTEQFN 615
CC+ QL+ N+ + + RCP+C++N + C + C+ DQS Y+ KT ++
Sbjct: 88 TKTCCSASQLDTFNYNMNIPRETMSRCPSCYKNLVNIYCFLTCSPDQSMYVNASKTTPYS 147
Query: 616 --------------GTHRRISEIDYYLSKTFMDGIYNSCSEVKLTSTNERSIKVMCGQWG 753
+ I+E+DY++ ++NSC V S+N + + + CG +G
Sbjct: 148 PPTPPPENTVQDKEAGQKSITEVDYFILNETAQAMFNSCINVNFPSSNTKVLSLYCGSYG 207
Query: 754 DA-CSAQRWFDNMGDASNYQVPFXINYKATDVP 849
A C+AQRW D MGD +N Q PF IN+K P
Sbjct: 208 AAHCTAQRWLDFMGDKNNEQTPFQINFKLGGAP 240
>UniRef50_UPI000069E05B Cluster: Niemann-Pick C1-like protein 1
precursor.; n=2; Xenopus tropicalis|Rep: Niemann-Pick
C1-like protein 1 precursor. - Xenopus tropicalis
Length = 1260
Score = 126 bits (304), Expect = 7e-28
Identities = 64/202 (31%), Positives = 102/202 (50%), Gaps = 13/202 (6%)
Frame = +1
Query: 277 SALAEDGHCIWYGVCANSTE------HKMVNCFYDGPAKPIEEKAMKIIEQYCPEIAKGG 438
+ + + G+C Y C + E ++ C + AK + E M ++ CP++ G
Sbjct: 11 TTIHQKGYCSMYEECGLNPEVSGSLIKPLIPCESNTEAKKVNEVHMTFLKDVCPQMVTGE 70
Query: 439 ---YSCCNYEQLNQLKVNIALAENLLGRCPTCFQNFLKPICGMACAVDQSKYLKPVKTEQ 609
Y CC+ +QL +K + AL++ +L RCP+C +NF C C+ DQS + +T
Sbjct: 71 DSTYVCCSIKQLQSIKASFALSKVILSRCPSCAENFANIYCQNICSPDQSTFTNVTRTHT 130
Query: 610 FN---GTHRRISEIDYYLSKTFMDGIYNSCSEVKLTSTNERSIKVMCGQWG-DACSAQRW 777
N + + E D Y + F D +NSC V+L +T +I MCG++G + C++QRW
Sbjct: 131 MNVSGNIEQGVLEYDCYFRRQFADESFNSCKNVRLPATGGYAIAAMCGKYGAELCTSQRW 190
Query: 778 FDNMGDASNYQVPFXINYKATD 843
D GD SN P IN+ D
Sbjct: 191 LDFQGDTSNGLAPLDINFNLMD 212
>UniRef50_UPI00015B5F3E Cluster: PREDICTED: similar to CG5722-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
CG5722-PA - Nasonia vitripennis
Length = 1253
Score = 120 bits (289), Expect = 5e-26
Identities = 60/186 (32%), Positives = 99/186 (53%), Gaps = 5/186 (2%)
Frame = +1
Query: 289 EDGHCIWYGVCANSTEHKMVNCFYDGPAKPIEEKAMK-IIEQYCP---EIAKGGYSCCNY 456
+D C+WYG C S +++ NC + A+PI+++A K I + CP E +CC+
Sbjct: 22 DDYTCVWYGQCGFSENNRVRNCLDETSAQPIDDEAAKAIFRKRCPHFYEKTDDPPTCCDA 81
Query: 457 EQLNQLKVNIALAENLLGRCPTCFQNFLKPICGMACAVDQSKYLKPVKTEQFNGTHRRIS 636
EQ++ + N+ +AE + GRC TC +N + IC CA DQS+++ K N I
Sbjct: 82 EQISTMADNMNMAEQVFGRCSTCLRNLFRSICDFTCAADQSRFMNATKIVNDNW----IE 137
Query: 637 EIDYYLSKTFMDGIYNSCSEVKLTSTNERSIKVMCGQWGDACSAQRWFDNMGDASNYQ-V 813
I+ +L + + + Y SC + ++ ++ + C + C+ +RWFD MGD V
Sbjct: 138 SIEIFLDEAYANATYESCKNIVNPTSGTLTMDMAC-KGAKKCNPRRWFDLMGDDEAMPFV 196
Query: 814 PFXINY 831
PF +NY
Sbjct: 197 PFKMNY 202
>UniRef50_Q4RWY5 Cluster: Chromosome 15 SCAF14981, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 15 SCAF14981, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1209
Score = 109 bits (261), Expect = 1e-22
Identities = 51/154 (33%), Positives = 84/154 (54%), Gaps = 1/154 (0%)
Frame = +1
Query: 403 IEQYCPEIAKGGYS-CCNYEQLNQLKVNIALAENLLGRCPTCFQNFLKPICGMACAVDQS 579
+++ CP G S CC+ QL+ LK ++ + L RCP CF N + C + C+ QS
Sbjct: 3 LQELCPGYDYGNRSLCCDVNQLHTLKESLEVPLQFLSRCPACFFNLVNLFCELTCSPHQS 62
Query: 580 KYLKPVKTEQFNGTHRRISEIDYYLSKTFMDGIYNSCSEVKLTSTNERSIKVMCGQWGDA 759
+++ K +G + E+ YY+ TF + +YN+C +V+ S+N +++ ++CG+
Sbjct: 63 QFMNATK---LSGPD--VVEVQYYIGLTFANAMYNACRDVQAPSSNVKALSLLCGKDAKD 117
Query: 760 CSAQRWFDNMGDASNYQVPFXINYKATDVPVDGY 861
C+A W M + N Q PF I +DVPV GY
Sbjct: 118 CNATNWIQYMFNTDNEQAPFPITPIFSDVPVSGY 151
>UniRef50_UPI000065FF0C Cluster: Niemann-Pick C1-like protein 1
precursor.; n=1; Takifugu rubripes|Rep: Niemann-Pick
C1-like protein 1 precursor. - Takifugu rubripes
Length = 1293
Score = 106 bits (254), Expect = 8e-22
Identities = 53/154 (34%), Positives = 89/154 (57%), Gaps = 8/154 (5%)
Frame = +1
Query: 397 KIIEQYCPEIAKGG---YSCCNYEQLNQLKVNIALAENLLGRCPTCFQNFLKPICGMACA 567
K +++ CP + KG Y+CC+ +QLN L+ +++L++ +L RCP+C NF C C+
Sbjct: 45 KKLKEVCPMLDKGEANTYACCSEKQLNSLEKSLSLSKVVLIRCPSCADNFAHLHCITTCS 104
Query: 568 VDQSKYLKPVKTEQFNGTHR--RISEIDY--YLSKTFMDGIYNSCSEVKLTSTNERSIKV 735
Q+K ++ K G + R + + Y +L TF D + SC V++ +T +I
Sbjct: 105 PQQTKTIQVTKVMNVTGNDKITREAVVGYTAFLGTTFADASFQSCKNVRIPATGGFAIAT 164
Query: 736 MCGQWGD-ACSAQRWFDNMGDASNYQVPFXINYK 834
MCG++G C+AQRW+D GD+SN P I+++
Sbjct: 165 MCGRYGSKLCNAQRWYDFQGDSSNGLAPLDIDFR 198
>UniRef50_UPI0000DB7411 Cluster: PREDICTED: similar to Niemann-Pick
Type C-1 CG5722-PA; n=1; Apis mellifera|Rep: PREDICTED:
similar to Niemann-Pick Type C-1 CG5722-PA - Apis
mellifera
Length = 1238
Score = 104 bits (250), Expect = 3e-21
Identities = 49/175 (28%), Positives = 92/175 (52%), Gaps = 9/175 (5%)
Frame = +1
Query: 298 HCIWYGVCANSTEHKMVNCFYDGPAKPIEEKAMKIIEQYCPEIAKGGYS---CCNYEQLN 468
HC+W G C + C + P +PI+ ++ + + CP +G S CC+ + +
Sbjct: 30 HCVWRGNCGFTELGVSRTCASNDPPEPIDPQSNSNLREKCPHYFEGKDSPELCCDADNVK 89
Query: 469 QLKVNIALAENLLGRCPTCFQNFLKPICGMACAVDQSKYLKPVKTEQFNGTH-----RRI 633
L N+ +AE++ GRCPTC +N K +C + C+ +QSK+L+ KT T +
Sbjct: 90 TLIENLNMAESIFGRCPTCLKNVYKLLCDLVCSPEQSKFLRVTKTGNNYTTESGKRKEYV 149
Query: 634 SEIDYYLSKTFMDGIYNSCSEVKLTSTNERSIKVMCGQW-GDACSAQRWFDNMGD 795
EI+ Y+ + +M+ Y+SC V + + + ++ + CG + C+ + W++ G+
Sbjct: 150 EEIEVYVEEEYMNKTYDSCKYVVMPQSGKLAMDLACGIYDASTCTPKLWYEYQGN 204
>UniRef50_Q9SVF0 Cluster: Putative uncharacterized protein
F22I13.120; n=2; Arabidopsis thaliana|Rep: Putative
uncharacterized protein F22I13.120 - Arabidopsis
thaliana (Mouse-ear cress)
Length = 1055
Score = 102 bits (245), Expect = 1e-20
Identities = 55/180 (30%), Positives = 95/180 (52%), Gaps = 3/180 (1%)
Frame = +1
Query: 310 YGVCANSTEHKMVNCFYDGPAKPIEEKAMKIIEQYCPEIAKGGYSCCNYEQLNQLKVNIA 489
Y +C + ++ K++NC Y P+ +E I+ CP I+ G CC Q + L+ +
Sbjct: 2 YDICGHRSDGKVLNCPYASPSIQPDELFSAKIQSLCPTIS--GNVCCTETQFDTLRSQVQ 59
Query: 490 LAENLLGRCPTCFQNFLKPICGMACAVDQSKYLKPVKTEQFNGTHRRISEIDYYLSKTFM 669
A L CP C +NFL C ++C+ +QS ++ + +G + + IDY+++ TF
Sbjct: 60 QAVPFLVGCPACLRNFLNLFCELSCSPNQSLFINVTSVAEVSG-NLTVDGIDYHITDTFG 118
Query: 670 DGIYNSCSEVKLTSTNERSIKVMCGQWGDACSAQRWFDNMGD--ASNYQ-VPFXINYKAT 840
+G+Y SC EVK + N R+I + G A + + WF +G S + P+ IN+K++
Sbjct: 119 EGLYESCKEVKFGTMNTRAINFV---GGGAKNFREWFTFIGQKAPSGFPGSPYAINFKSS 175
>UniRef50_Q01KH5 Cluster: H0409D10.4 protein; n=5; Eukaryota|Rep:
H0409D10.4 protein - Oryza sativa (Rice)
Length = 1372
Score = 102 bits (245), Expect = 1e-20
Identities = 52/180 (28%), Positives = 88/180 (48%)
Frame = +1
Query: 292 DGHCIWYGVCANSTEHKMVNCFYDGPAKPIEEKAMKIIEQYCPEIAKGGYSCCNYEQLNQ 471
+G+C YG+CA ++ K++NC A + I+ CP I G CC +Q +
Sbjct: 50 EGYCSMYGICAQRSDGKVLNCVNATKAVKPDTLFSARIQSLCPTIT--GDVCCTVDQFDT 107
Query: 472 LKVNIALAENLLGRCPTCFQNFLKPICGMACAVDQSKYLKPVKTEQFNGTHRRISEIDYY 651
L + A L CP C +NFL C M+C+ +QS ++ +Q N T ++ IDYY
Sbjct: 108 LHQQVQQAIPFLVGCPACLRNFLNLFCEMSCSPNQSLFINVTSVKQVNNT-MTVNGIDYY 166
Query: 652 LSKTFMDGIYNSCSEVKLTSTNERSIKVMCGQWGDACSAQRWFDNMGDASNYQVPFXINY 831
++ T+ + +YNSC +VK + N R++ + G + + D + P+ I +
Sbjct: 167 VTSTYGEELYNSCKDVKFGTLNTRAMDFLGGGAKNYKEWMAFIGRQADLNQIGSPYLITF 226
>UniRef50_Q9UHC9 Cluster: Niemann-Pick C1-like protein 1 precursor;
n=23; Tetrapoda|Rep: Niemann-Pick C1-like protein 1
precursor - Homo sapiens (Human)
Length = 1359
Score = 102 bits (245), Expect = 1e-20
Identities = 53/196 (27%), Positives = 98/196 (50%), Gaps = 11/196 (5%)
Frame = +1
Query: 277 SALAEDGHCIWYGVCANSTEHK-------MVNCFYDGPAKPIEEKAMKIIEQYCPEIAKG 435
+ + + G+C +Y C + E V+C + PA+ I + ++++ CP + G
Sbjct: 25 TTIHQPGYCAFYDECGKNPELSGSLMTLSNVSCLSNTPARKITGDHLILLQKICPRLYTG 84
Query: 436 G--YSCCNYEQLNQLKVNIALAENLLGRCPTCFQNFLKPICGMACAVDQSKYLKPVKTEQ 609
+CC+ +QL L+ ++++ + LL RCP C NF+ C C+ +QS ++ + Q
Sbjct: 85 PNTQACCSAKQLVSLEASLSITKALLTRCPACSDNFVNLHCHNTCSPNQSLFINVTRVAQ 144
Query: 610 FN-GTHRRISEIDYYLSKTFMDGIYNSCSEVKLTSTNERSIKVMCGQWGDA-CSAQRWFD 783
G + + + +F + Y+SCS V++ + ++ MCG +G A C+AQRW +
Sbjct: 145 LGAGQLPAVVAYEAFYQHSFAEQSYDSCSRVRVPAAATLAVGTMCGVYGSALCNAQRWLN 204
Query: 784 NMGDASNYQVPFXINY 831
GD N P I +
Sbjct: 205 FQGDTGNGLAPLDITF 220
>UniRef50_Q4T749 Cluster: Chromosome undetermined SCAF8317, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF8317,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 1132
Score = 98.7 bits (235), Expect = 2e-19
Identities = 48/136 (35%), Positives = 74/136 (54%), Gaps = 5/136 (3%)
Frame = +1
Query: 439 YSCCNYEQLNQLKVNIALAENLLGRCPTCFQNFLKPICGMACAVDQSKYLKPVKTEQFNG 618
Y+CC+ QL+ L+ ++AL++ +L RCP+C NF C C+ Q+K +K K G
Sbjct: 2 YACCSINQLSSLEASLALSKAVLIRCPSCADNFAHFHCITTCSPQQTKTIKVTKVTNVTG 61
Query: 619 ----THRRISEIDYYLSKTFMDGIYNSCSEVKLTSTNERSIKVMCGQWGDA-CSAQRWFD 783
T + YLS F D + SC V++ +T +I MCG++G C+ QRW+D
Sbjct: 62 FDNITREGVVGYAAYLSTNFADASFQSCKNVRIPATGGLAIGTMCGRFGSRHCNPQRWYD 121
Query: 784 NMGDASNYQVPFXINY 831
GD+SN P I++
Sbjct: 122 FQGDSSNGLAPLDIDF 137
>UniRef50_Q9SHN9 Cluster: F7F22.1; n=2; Arabidopsis thaliana|Rep:
F7F22.1 - Arabidopsis thaliana (Mouse-ear cress)
Length = 1275
Score = 96.3 bits (229), Expect = 9e-19
Identities = 48/174 (27%), Positives = 84/174 (48%)
Frame = +1
Query: 295 GHCIWYGVCANSTEHKMVNCFYDGPAKPIEEKAMKIIEQYCPEIAKGGYSCCNYEQLNQL 474
G+C Y +C ++ K++NC ++ P+ ++ I+ CP I G CC Q + L
Sbjct: 17 GYCAMYDICGARSDGKVLNCPFNIPSVKPDDLLSSKIQSLCPTIT--GNVCCTETQFDTL 74
Query: 475 KVNIALAENLLGRCPTCFQNFLKPICGMACAVDQSKYLKPVKTEQFNGTHRRISEIDYYL 654
+ + A + CP C +NFL C + C+ DQS ++ T + + + I YY+
Sbjct: 75 RSQVQQAIPFIVGCPACLRNFLNLFCELTCSPDQSLFINVTSTTKVK-NNSTVDGIQYYI 133
Query: 655 SKTFMDGIYNSCSEVKLTSTNERSIKVMCGQWGDACSAQRWFDNMGDASNYQVP 816
+ F G+Y SC VK S+N R++ + A + + WF +G + +P
Sbjct: 134 TDDFGAGMYESCKNVKFGSSNSRALDFL---GAGAKNFKEWFTFIGQKAGVNLP 184
>UniRef50_Q9VRC9 Cluster: CG12092-PA; n=4; Diptera|Rep: CG12092-PA -
Drosophila melanogaster (Fruit fly)
Length = 1223
Score = 94.3 bits (224), Expect = 4e-18
Identities = 53/175 (30%), Positives = 87/175 (49%), Gaps = 11/175 (6%)
Frame = +1
Query: 367 PAKPIEEKAMK-IIEQYCPEIAKG--GYS-------CCNYEQLNQLKVNIALAENLLGRC 516
PA+P+ + I + CP + K G S CC+ Q+ ++ ++ A+ + RC
Sbjct: 14 PARPLNSPTSEAIFAKRCPMLYKEYKGESGEDELSLCCDAAQIETMESGLSQADGVFSRC 73
Query: 517 PTCFQNFLKPICGMACAVDQSKYLKPVKTEQFNGTHRRISEIDYYLSKTFMDGIYNSCSE 696
PTC +N +C M CA + + +L G + IDY L+ + IYNSC
Sbjct: 74 PTCTRNMALTVCAMTCAKNHTLFLTAYNDTNDAGVD-YVKYIDYRLTDDTVSKIYNSCIG 132
Query: 697 VKLTSTNERSIKVMCGQW-GDACSAQRWFDNMGDASNYQVPFXINYKATDVPVDG 858
++ T T ++ + CG + C+ +RW++ MGD S VPF INYK ++ +G
Sbjct: 133 IQHTQTGRPAMDLGCGSYNAKTCNYRRWYEFMGDVSGDYVPFQINYKWSEDAEEG 187
>UniRef50_UPI0000E48444 Cluster: PREDICTED: similar to Niemann Pick
type C1; n=4; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to Niemann Pick type C1 -
Strongylocentrotus purpuratus
Length = 2289
Score = 93.5 bits (222), Expect = 6e-18
Identities = 45/132 (34%), Positives = 71/132 (53%), Gaps = 2/132 (1%)
Frame = +1
Query: 445 CCNYEQLNQLKVNIALAENLLGRCPTCFQNFLKPICGMACAVDQSKYLK-PVKTEQFNGT 621
CC+ +QL ++ + GRCP C +N L +C M C+ QS Y V +G
Sbjct: 1851 CCDLQQLRTMQPLLTALRPAFGRCPACLENILTMMCQMVCSPQQSLYTNATVLLVSDDGV 1910
Query: 622 HRRISEIDYYLSKTFMDGIYNSCSEVKLTSTNERSIKVMCGQW-GDACSAQRWFDNMGDA 798
+ D ++++ F D Y+SC +V+ + N + VMCG + GD CS QRW D +GD
Sbjct: 1911 --GVRRFDAFVAQEFADVAYDSCKDVQFPAANTPVMDVMCGGYLGDDCSPQRWLDFLGDT 1968
Query: 799 SNYQVPFXINYK 834
+N +P+ I++K
Sbjct: 1969 ANGFIPWNIDFK 1980
>UniRef50_A7QPC0 Cluster: Chromosome chr18 scaffold_137, whole
genome shotgun sequence; n=1; Vitis vinifera|Rep:
Chromosome chr18 scaffold_137, whole genome shotgun
sequence - Vitis vinifera (Grape)
Length = 1263
Score = 93.1 bits (221), Expect = 8e-18
Identities = 49/178 (27%), Positives = 88/178 (49%), Gaps = 3/178 (1%)
Frame = +1
Query: 310 YGVCANSTEHKMVNCFYDGPAKPIEEKAMKIIEQYCPEIAKGGYSCCNYEQLNQLKVNIA 489
Y +C ++ K++NC Y P+ ++ I+ CP I+ G CC Q + L+ +
Sbjct: 2 YDICGKRSDGKVLNCPYGSPSVKPDDLLSSKIQSMCPTIS--GNVCCTEAQFDTLRTQVQ 59
Query: 490 LAENLLGRCPTCFQNFLKPICGMACAVDQSKYLKPVKTEQFNGTHRRISEIDYYLSKTFM 669
A L CP C +NFL C + C+ +QS ++ + N + + I++ ++ F
Sbjct: 60 QAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVSKVN-NNLTVDGIEFIITDAFG 118
Query: 670 DGIYNSCSEVKLTSTNERSIKVMCGQWGDACSAQRWFDNMGDASNYQV---PFXINYK 834
+G+YNSC +VK + N R+I + A + + WF +G + V P+ IN++
Sbjct: 119 EGLYNSCKDVKFGTMNTRAIDFI---GAGAKTFKEWFAFIGTRAAPSVPGSPYAINFQ 173
>UniRef50_A5APM6 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 1050
Score = 93.1 bits (221), Expect = 8e-18
Identities = 49/178 (27%), Positives = 88/178 (49%), Gaps = 3/178 (1%)
Frame = +1
Query: 310 YGVCANSTEHKMVNCFYDGPAKPIEEKAMKIIEQYCPEIAKGGYSCCNYEQLNQLKVNIA 489
Y +C ++ K++NC Y P+ ++ I+ CP I+ G CC Q + L+ +
Sbjct: 2 YDICGKRSDGKVLNCPYGSPSVKPDDLLSSKIQSMCPTIS--GNVCCTEAQFDTLRTQVQ 59
Query: 490 LAENLLGRCPTCFQNFLKPICGMACAVDQSKYLKPVKTEQFNGTHRRISEIDYYLSKTFM 669
A L CP C +NFL C + C+ +QS ++ + N + + I++ ++ F
Sbjct: 60 QAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVSKVN-NNLTVDGIEFIITDAFG 118
Query: 670 DGIYNSCSEVKLTSTNERSIKVMCGQWGDACSAQRWFDNMGDASNYQV---PFXINYK 834
+G+YNSC +VK + N R+I + A + + WF +G + V P+ IN++
Sbjct: 119 EGLYNSCKDVKFGTMNTRAIDFI---GAGAKTFKEWFAFIGTRAAPSVPGSPYAINFQ 173
>UniRef50_Q5KGS9 Cluster: Vacuolar membrane protein, putative; n=2;
Filobasidiella neoformans|Rep: Vacuolar membrane
protein, putative - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 1330
Score = 89.0 bits (211), Expect = 1e-16
Identities = 53/196 (27%), Positives = 90/196 (45%), Gaps = 5/196 (2%)
Frame = +1
Query: 271 IPSALAEDGH--CIWYGVCANSTEHKM-VNCFYDGPAKPIEEKAMKIIEQYC-PEIAKGG 438
+PS+ + G C G C ++ + C D A +++ + ++ C P +
Sbjct: 1 MPSSQSRSGKGICAMRGTCGKTSMFGADLPCPDDSDATVPDQRLLDLMASVCGPSYSLPD 60
Query: 439 YSCCNYEQLNQLKVNIALAENLLGRCPTCFQNFLKPICGMACAVDQSKYLKPVKTEQFNG 618
+ CC Y+QL+ L + A L+ CP C NF C C+ +QS +L T++
Sbjct: 61 HVCCTYDQLSTLSDRLQQAAPLIASCPACINNFRSFYCDFTCSPNQSTFLSVTATQKTTE 120
Query: 619 THRRISEIDYYLSKTFMDGIYNSCSEVKLTSTNERSIKVMCGQWGDACSAQRWFDNMGD- 795
+ E+DY +S F G Y+SC +V+ +TN ++ ++ G A +A + MGD
Sbjct: 121 GKDAVKEVDYEVSSDFKQGFYDSCKDVQFGATNGFAMDLI---GGGATNASGFLKYMGDL 177
Query: 796 ASNYQVPFXINYKATD 843
PF IN+ D
Sbjct: 178 RPGLGSPFQINFPDND 193
>UniRef50_A2QWF9 Cluster: Remark: Niemann-Pick C precursor; n=16;
Pezizomycotina|Rep: Remark: Niemann-Pick C precursor -
Aspergillus niger
Length = 1277
Score = 87.8 bits (208), Expect = 3e-16
Identities = 52/183 (28%), Positives = 84/183 (45%), Gaps = 1/183 (0%)
Frame = +1
Query: 289 EDGHCIWYGVCANSTEHK-MVNCFYDGPAKPIEEKAMKIIEQYCPEIAKGGYSCCNYEQL 465
E G C G C + + C +G A+ E K + C + G CC EQ+
Sbjct: 34 EPGRCAIRGHCGKKSFFGGELPCPDNGLAQQPEPAVRKKLVDLCGSKWEEGPVCCLDEQI 93
Query: 466 NQLKVNIALAENLLGRCPTCFQNFLKPICGMACAVDQSKYLKPVKTEQFNGTHRRISEID 645
+ L N+ LAE ++ CP C NF C C+ DQS ++ ++ G + ++EID
Sbjct: 94 DALSKNLKLAEGIIASCPACKDNFFNIFCTFTCSPDQSLFVNVTDIDEARGGKQLVTEID 153
Query: 646 YYLSKTFMDGIYNSCSEVKLTSTNERSIKVMCGQWGDACSAQRWFDNMGDASNYQVPFXI 825
S+ + G Y+SC VK ++ ++I + G A + ++ +GD PF I
Sbjct: 154 NIWSEQYQSGFYDSCKNVKNGASGGKAIDFI---GGGAKNYSQFLKFLGDKKLLGSPFQI 210
Query: 826 NYK 834
N+K
Sbjct: 211 NFK 213
>UniRef50_Q12200 Cluster: Niemann-pick type C-related protein 1
precursor; n=7; Saccharomycetales|Rep: Niemann-pick type
C-related protein 1 precursor - Saccharomyces cerevisiae
(Baker's yeast)
Length = 1170
Score = 85.8 bits (203), Expect = 1e-15
Identities = 50/184 (27%), Positives = 90/184 (48%), Gaps = 6/184 (3%)
Frame = +1
Query: 301 CIWYGVCAN-STEHKMVNCFYDGPAKP--IEEKAMKIIEQYCPEIAKG-GYSCCNYEQLN 468
C YG C S + C +P + ++ K++ + C E K Y+CC +Q+
Sbjct: 23 CAMYGNCGKKSVFGNELPCPVPRSFEPPVLSDETSKLLVEVCGEEWKEVRYACCTKDQVV 82
Query: 469 QLKVNIALAENLLGRCPTCFQNFLKPICGMACAVDQSKYLKPVKTEQFNGTHRRISEIDY 648
L+ N+ A+ L+ CP C +NF C CA DQ +++ K E+ ++E+D
Sbjct: 83 ALRDNLQKAQPLISSCPACLKNFNNLFCHFTCAADQGRFVNITKVEKSKEDKDIVAELDV 142
Query: 649 YLSKTFMDGIYNSCSEVKLTSTNERSIKVMCGQWGDACSAQRWFDNMGDASNY--QVPFX 822
+++ ++ Y+SC +K ++TN ++ ++ G A + ++ +GDA PF
Sbjct: 143 FMNSSWASEFYDSCKNIKFSATNGYAMDLI---GGGAKNYSQFLKFLGDAKPMLGGSPFQ 199
Query: 823 INYK 834
INYK
Sbjct: 200 INYK 203
>UniRef50_Q19127 Cluster: Niemann-Pick C1 protein homolog 1
precursor; n=2; Caenorhabditis|Rep: Niemann-Pick C1
protein homolog 1 precursor - Caenorhabditis elegans
Length = 1383
Score = 84.6 bits (200), Expect = 3e-15
Identities = 52/183 (28%), Positives = 87/183 (47%), Gaps = 16/183 (8%)
Frame = +1
Query: 292 DGHCIWYGVCANSTEHKMVNCFY-DGPAKPIE----EKAMKIIEQYCPEIAKGGYS-CCN 453
D CI G+C TE+ C D +P A + + ++CP + G CC
Sbjct: 19 DAGCIMRGLCQKHTENAYGPCVTNDTNVEPTAFDKTHPAYEKMVEFCPHLLTGDNKLCCT 78
Query: 454 YEQLNQLKVNIALAENLLGRCPTCFQNFLKPICGMACAVDQSKY-----LKPVK-----T 603
Q L IA A ++LGRCP+CF NF K C C+ +Q + +KP++ T
Sbjct: 79 PSQAEGLTKQIAQARHILGRCPSCFDNFAKLWCEFTCSPNQQDFVSISEMKPIEKKEGFT 138
Query: 604 EQFNGTHRRISEIDYYLSKTFMDGIYNSCSEVKLTSTNERSIKVMCGQWGDACSAQRWFD 783
++ ++ ++Y LS F +G+++SC +V T + +++VMC C+ W +
Sbjct: 139 PEYQPAEAYVNTVEYRLSTDFAEGMFSSCKDV--TFGGQPALRVMC--TSTPCTLTNWLE 194
Query: 784 NMG 792
+G
Sbjct: 195 FIG 197
>UniRef50_Q6QVL7 Cluster: NPC1 precursor; n=1; Ornithodoros
moubata|Rep: NPC1 precursor - Ornithodoros moubata (Soft
tick)
Length = 228
Score = 83.4 bits (197), Expect = 7e-15
Identities = 56/197 (28%), Positives = 91/197 (46%), Gaps = 8/197 (4%)
Frame = +1
Query: 277 SALAEDGHCIWYGVCANSTE-HKMVNCFYDGPAKPIEEKAMKIIEQYCPEIAKG----GY 441
S LA C+ G C + + K V C D KP+ ++ + CP+IA
Sbjct: 17 STLASASRCVMRGHCGHDEDLDKAVPCKVDHEPKPLLSSNRDLLSEVCPDIAAALGPDRR 76
Query: 442 SCCNYEQLNQLKVNIALAENL-LGRCPTCFQNFLKPICGMACAVDQSKYLKPVKTEQFNG 618
+CC+ EQL LK ++ +L + P C +NF C + C+ QS ++K V +
Sbjct: 77 TCCDVEQLQALKDDLQQPIDLGMKDSPRCLKNFRNIFCQILCSPRQSDFVKVVTAKNNTM 136
Query: 619 THRRISEIDYYLSKTFMDGIYNSCSEVKLTSTNERSIKVMCGQWGDACSAQRWFDNMGDA 798
+E Y +S+ F G Y+SC VK+ + MCG W C+A +WF +G
Sbjct: 137 GLPYATEAVYAVSEKFAKGSYDSCKNVKVKKI-LNMMYFMCG-W--TCNANKWFTFLGST 192
Query: 799 SNY--QVPFXINYKATD 843
S+ P+ I+++ +
Sbjct: 193 SSEGGYSPYKIDFRIVE 209
>UniRef50_Q6CBA1 Cluster: Similar to tr|Q12200 Saccharomyces
cerevisiae YPL006W NCR1; n=1; Yarrowia lipolytica|Rep:
Similar to tr|Q12200 Saccharomyces cerevisiae YPL006W
NCR1 - Yarrowia lipolytica (Candida lipolytica)
Length = 1239
Score = 74.1 bits (174), Expect = 4e-12
Identities = 34/128 (26%), Positives = 65/128 (50%), Gaps = 1/128 (0%)
Frame = +1
Query: 364 GPAKPIEEKAMKIIEQYCPEI-AKGGYSCCNYEQLNQLKVNIALAENLLGRCPTCFQNFL 540
GP +P + + ++ + C E+ CC+ Q+ LK ++ A+ L+ CP C NF
Sbjct: 53 GPFEP-SKGDLDLLGEICGEVWTHEKLLCCDTAQIKDLKNSLKKADGLISSCPACKSNFY 111
Query: 541 KPICGMACAVDQSKYLKPVKTEQFNGTHRRISEIDYYLSKTFMDGIYNSCSEVKLTSTNE 720
+ C CA DQ Y+ + + ++E+ YY+ + G Y+SC ++K ++TN
Sbjct: 112 EFFCKFTCAPDQRDYVNVTQLGKSTDGRDIVTELSYYVKPEWAQGFYDSCKDIKFSATNG 171
Query: 721 RSIKVMCG 744
++ ++ G
Sbjct: 172 YAMDLLGG 179
>UniRef50_A3GGU6 Cluster: Predicted protein; n=5;
Saccharomycetales|Rep: Predicted protein - Pichia
stipitis (Yeast)
Length = 1268
Score = 73.3 bits (172), Expect = 7e-12
Identities = 47/190 (24%), Positives = 84/190 (44%), Gaps = 4/190 (2%)
Frame = +1
Query: 277 SALAEDGHCIWYGVCAN-STEHKMVNCFYDGPAKPIEEKAMKIIEQYCPEIAKGGYSCCN 453
+ + + G+C Y C S + C + A K +++ Q C + CC+
Sbjct: 18 ATIHKSGYCAMYDNCGKKSVFGSSLPCVANVKAVEPSAKTAQLLHQICGDDFDTSKVCCS 77
Query: 454 YEQLNQLKVNIALAENLLGRCPTCFQNFLKPICGMACAVDQSKYLKPVKTEQFNGTHRRI 633
+Q+ ++ N+ + ++ CP C +NF C C+ DQS +L KT T I
Sbjct: 78 EDQVVNMESNLKRVDPIISSCPACRKNFYDFFCKFTCSPDQSTFLNITKTAIAADTKNEI 137
Query: 634 -SEIDYYLSKTFMDGIYNSCSEVKLTSTNERSIKVMCGQWGDACSAQRWFDNMGDASNY- 807
+E+ ++ Y SC+ VK ++TN ++ ++ G A + ++ +GD
Sbjct: 138 VAELSQFVDPGTAKDFYKSCANVKFSATNGYAMDLI---GGGAKNYLQFLKFLGDEKPLL 194
Query: 808 -QVPFXINYK 834
PF INYK
Sbjct: 195 GGSPFQINYK 204
>UniRef50_Q4PE83 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 1489
Score = 71.3 bits (167), Expect = 3e-11
Identities = 41/142 (28%), Positives = 70/142 (49%), Gaps = 5/142 (3%)
Frame = +1
Query: 421 EIAKGGYSCCNYEQLNQLKVNIALAENLLGRCPTCFQNFLKPICGMACAVDQSKYLKPVK 600
E A+G CC Q+ L N+ AE L+ CP C NF C C+ DQ++++ V+
Sbjct: 57 EFAEGPV-CCTEAQVENLSANLQQAEPLISSCPACRNNFRSLFCSFTCSPDQAQFVDVVE 115
Query: 601 TEQFNGTHRRISE----IDYYLSKTFMDGIYNSCSEVKLTSTNERSIKVMCGQWGDACSA 768
T+Q G+ + SE ++YY+ + ++SC VK ++N ++ ++ G A +
Sbjct: 116 TQQVTGSDGKPSEAVKTVEYYIDAEWKQKFFDSCKNVKFGASNGFAMDLI---GGGAQTP 172
Query: 769 QRWFDNMGDASN-YQVPFXINY 831
+ +GD PF IN+
Sbjct: 173 NAFLKFLGDEKPLLGSPFQINF 194
>UniRef50_UPI0000D573E9 Cluster: PREDICTED: similar to CG5722-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG5722-PA - Tribolium castaneum
Length = 1210
Score = 68.9 bits (161), Expect = 2e-10
Identities = 41/158 (25%), Positives = 78/158 (49%), Gaps = 4/158 (2%)
Frame = +1
Query: 382 EEKAMKIIEQYCPEIAKGGYS---CCNYEQLNQLKVNIALAENLLGRCPTCFQNFLKPIC 552
EE K+IE YCP + CC+ +Q + ++ + RCP C N + C
Sbjct: 34 EEARQKLIE-YCPFFFENNDDPELCCDVDQALNM-IDGFRSTVPFQRCPACVTNIINTYC 91
Query: 553 GMACAVDQSKYLKPVKTEQFNGTHRRISEIDYYLSKTFMDGIYNSCSEVKLTSTNERSIK 732
+C+ DQ + T + + + ++ + + ++ +Y+SC V ST+ + I+
Sbjct: 92 IFSCSPDQYDF-----TLTLDYKNDYVLKVQENIDENYIQAVYDSCKNVANPSTSSKLIE 146
Query: 733 VMCGQWGDA-CSAQRWFDNMGDASNYQVPFXINYKATD 843
++CG++G A C+ +R+F+ MG SN P I + + +
Sbjct: 147 LVCGKYGAAYCTPERFFNYMGSTSNGFAPIDIVFNSVN 184
>UniRef50_P34389 Cluster: Niemann-Pick C1 protein homolog 2
precursor; n=2; Caenorhabditis|Rep: Niemann-Pick C1
protein homolog 2 precursor - Caenorhabditis elegans
Length = 1274
Score = 68.9 bits (161), Expect = 2e-10
Identities = 33/102 (32%), Positives = 56/102 (54%), Gaps = 3/102 (2%)
Frame = +1
Query: 394 MKIIEQYCPEIAKG---GYSCCNYEQLNQLKVNIALAENLLGRCPTCFQNFLKPICGMAC 564
M E+YC + + CC QL + I+ A +LG CP+CF NF K C C
Sbjct: 66 MARFEKYCSYLVQEEDKAQVCCTELQLKGMTDRISNAATILGSCPSCFDNFAKLWCQFTC 125
Query: 565 AVDQSKYLKPVKTEQFNGTHRRISEIDYYLSKTFMDGIYNSC 690
+ DQSK++K ++T G + ++++ +++ F++G+Y SC
Sbjct: 126 SPDQSKFMKVMET---TGPKNVVVKMEFKVNRDFVEGLYESC 164
>UniRef50_Q54ED0 Cluster: Putative transmembrane protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative transmembrane
protein - Dictyostelium discoideum AX4
Length = 243
Score = 60.9 bits (141), Expect = 4e-08
Identities = 32/87 (36%), Positives = 43/87 (49%)
Frame = +1
Query: 442 SCCNYEQLNQLKVNIALAENLLGRCPTCFQNFLKPICGMACAVDQSKYLKPVKTEQFNGT 621
+CC Q N LK I E L G+CP C N CG C+ Q ++ P TE T
Sbjct: 73 ACCYTYQTNGLKTFIQSNETLFGQCPGCLANVWSLWCGSICSPFQQSFMVP--TETITQT 130
Query: 622 HRRISEIDYYLSKTFMDGIYNSCSEVK 702
++ +ID+ L F G+Y SCS +K
Sbjct: 131 -LQVVKIDFILHPDFAQGLYESCSSIK 156
>UniRef50_Q55BN1 Cluster: NPC1 protein; n=2; Dictyostelium
discoideum|Rep: NPC1 protein - Dictyostelium discoideum
AX4
Length = 1342
Score = 51.2 bits (117), Expect = 3e-05
Identities = 25/86 (29%), Positives = 39/86 (45%)
Frame = +1
Query: 442 SCCNYEQLNQLKVNIALAENLLGRCPTCFQNFLKPICGMACAVDQSKYLKPVKTEQFNGT 621
SCC Q L N+ + + RCP C N C +C+ Q ++ P + G
Sbjct: 78 SCCTNGQTLVLLSNMVMGSAVFARCPACLFNVWDLWCASSCSPYQQSFMVPTSIDSKTG- 136
Query: 622 HRRISEIDYYLSKTFMDGIYNSCSEV 699
+I +D+ + + G+YNSCS V
Sbjct: 137 --QILSVDFVIHPDYAWGLYNSCSGV 160
>UniRef50_A2XWG3 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. indica (Rice)
Length = 1158
Score = 46.0 bits (104), Expect = 0.001
Identities = 28/102 (27%), Positives = 49/102 (48%), Gaps = 1/102 (0%)
Frame = +1
Query: 529 QNFLKPICG-MACAVDQSKYLKPVKTEQFNGTHRRISEIDYYLSKTFMDGIYNSCSEVKL 705
Q+ I G + C VDQ L + +Q N T ++ IDYY++ T+ + +YNSC +VK
Sbjct: 63 QSLCPTITGDVCCTVDQFDTLHQ-QVQQVNNT-MTVNGIDYYVTSTYGEELYNSCKDVKF 120
Query: 706 TSTNERSIKVMCGQWGDACSAQRWFDNMGDASNYQVPFXINY 831
+ N R++ + G + + D + P+ I +
Sbjct: 121 GTLNTRAMDFLGGGAKNYKEWMAFIGRQADLNQIGSPYLITF 162
Score = 41.5 bits (93), Expect = 0.027
Identities = 20/72 (27%), Positives = 33/72 (45%)
Frame = +1
Query: 292 DGHCIWYGVCANSTEHKMVNCFYDGPAKPIEEKAMKIIEQYCPEIAKGGYSCCNYEQLNQ 471
+G+C YG+CA ++ K++NC A + I+ CP I G CC +Q +
Sbjct: 25 EGYCSMYGICAQRSDGKVLNCVNATKAVKPDTLFSARIQSLCPTIT--GDVCCTVDQFDT 82
Query: 472 LKVNIALAENLL 507
L + N +
Sbjct: 83 LHQQVQQVNNTM 94
>UniRef50_A4SA60 Cluster: Predicted protein; n=1; Ostreococcus
lucimarinus CCE9901|Rep: Predicted protein -
Ostreococcus lucimarinus CCE9901
Length = 505
Score = 34.3 bits (75), Expect = 4.0
Identities = 16/45 (35%), Positives = 25/45 (55%), Gaps = 3/45 (6%)
Frame = -2
Query: 430 WLSRDNIAQLFS--LPFLRSV*QVHHRNN-SPFYVLCCWHKRRTI 305
W++ D ++F+ PF+ V H N +PF VLCCW+ T+
Sbjct: 295 WVAHDMSGRMFTKEFPFVHDVVSSHALNGGAPFQVLCCWNGLLTL 339
>UniRef50_UPI00015B5F5A Cluster: PREDICTED: similar to zinc finger,
NFX1-type containing 1; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to zinc finger, NFX1-type containing 1
- Nasonia vitripennis
Length = 1920
Score = 33.5 bits (73), Expect = 7.1
Identities = 21/87 (24%), Positives = 32/87 (36%), Gaps = 3/87 (3%)
Frame = +1
Query: 313 GVCANSTEHKMVNCFYDGPAKPIEEKAMKIIEQYCPEIAKGGYSC---CNYEQLNQLKVN 483
G+C E + C + K E+ + CP+I G+ C C + +V
Sbjct: 1366 GLCPIPVEKDSLGCGHKVKVKCSEDATPSKCDGACPKILPCGHQCINKCKDQCTVSCQVM 1425
Query: 484 IALAENLLGRCPTCFQNFLKPICGMAC 564
+A G C C Q + CG C
Sbjct: 1426 LACDHFCKGNCGDCGQGRIHVFCGEPC 1452
>UniRef50_Q5LFD2 Cluster: Putative DNA-binding protein; n=1;
Bacteroides fragilis NCTC 9343|Rep: Putative DNA-binding
protein - Bacteroides fragilis (strain ATCC 25285 / NCTC
9343)
Length = 338
Score = 33.5 bits (73), Expect = 7.1
Identities = 22/88 (25%), Positives = 40/88 (45%)
Frame = +1
Query: 340 KMVNCFYDGPAKPIEEKAMKIIEQYCPEIAKGGYSCCNYEQLNQLKVNIALAENLLGRCP 519
KMV FY+ + IE + +E+Y E++ GY C + L +LK+ A N+ +
Sbjct: 44 KMVADFYEVEERTIE----RYLEKYSDELSANGYVLCKGKHLKELKLQFAPVINVGSKTT 99
Query: 520 TCFQNFLKPICGMACAVDQSKYLKPVKT 603
+ M + +S+ K V++
Sbjct: 100 QLGLFNFRSFLNMGMLLTESEQAKKVRS 127
>UniRef50_Q22UV0 Cluster: Hypothetical repeat containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Hypothetical
repeat containing protein - Tetrahymena thermophila
SB210
Length = 2718
Score = 33.5 bits (73), Expect = 7.1
Identities = 27/112 (24%), Positives = 48/112 (42%), Gaps = 6/112 (5%)
Frame = +1
Query: 415 CPEIAKGGYSCCNYEQLNQLKVNIALAENLLGRCPTCFQ-----NFLKPICGMACAVDQS 579
CP+I C NY Q + + N L+EN C Q N K C + CA++
Sbjct: 97 CPDI--NCLDCDNYGQCKKCQENYQLSENKQCLIDLCLQNEGVYNTQKGYCSLDCALENQ 154
Query: 580 KYLKPVKTEQ-FNGTHRRISEIDYYLSKTFMDGIYNSCSEVKLTSTNERSIK 732
++ + +Q F H +I++ID + + + + K +T+ +K
Sbjct: 155 --IQQINCKQNFEEDHDQINDIDISSYSSLSNANFIQIHKYKKYNTSYNEVK 204
>UniRef50_Q9LC43 Cluster: TagG homolog; n=20; Staphylococcus|Rep:
TagG homolog - Staphylococcus aureus
Length = 349
Score = 33.1 bits (72), Expect = 9.3
Identities = 24/93 (25%), Positives = 46/93 (49%), Gaps = 3/93 (3%)
Frame = -3
Query: 540 QKVLKARRASPQQIFRKGDIHFEL--VQLFVIAARITSFGYLGTILLNYFHCLFFDRF-S 370
Q +L+ +A Q+ + ++F L + +++ +R +G+LG +LL C+F + S
Sbjct: 86 QGILEGTKAITQKFNQVSKMNFPLSIIPTYIVTSRF--YGHLGLLLLVIIACMFTGIYPS 143
Query: 369 RSIIETIHHFMFCAVGTNAVPYAVTIFGQSRRD 271
II+ + + FC T +V + G RD
Sbjct: 144 IHIIQLLIYVPFCFFLTASVTLLTSTLGVLVRD 176
>UniRef50_A2ECX9 Cluster: Putative uncharacterized protein; n=1;
Trichomonas vaginalis G3|Rep: Putative uncharacterized
protein - Trichomonas vaginalis G3
Length = 417
Score = 33.1 bits (72), Expect = 9.3
Identities = 16/44 (36%), Positives = 22/44 (50%)
Frame = +1
Query: 376 PIEEKAMKIIEQYCPEIAKGGYSCCNYEQLNQLKVNIALAENLL 507
P + +K+++ C E KGGY C E + N AENLL
Sbjct: 73 PFLKVTLKLLKLCCSETFKGGYPCILIEYIEYNLQNFESAENLL 116
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 791,629,460
Number of Sequences: 1657284
Number of extensions: 15741562
Number of successful extensions: 41816
Number of sequences better than 10.0: 36
Number of HSP's better than 10.0 without gapping: 40438
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 41762
length of database: 575,637,011
effective HSP length: 100
effective length of database: 409,908,611
effective search space used: 76652910257
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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