Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P08_pT_D03
(804 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein. 368 e-101
CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein. 368 e-101
BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein pr... 368 e-101
BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein. 368 e-101
AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitr... 368 e-101
AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein. 368 e-101
BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenas... 367 e-101
CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein. 365 e-101
AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitra... 360 4e-99
DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenas... 357 3e-98
X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase... 327 2e-89
U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase ... 326 4e-89
BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenas... 326 4e-89
BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenas... 326 4e-89
AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenas... 325 1e-88
AF197566-1|AAG43470.1| 127|Homo sapiens NADP+-specific isocitra... 126 1e-28
U62389-1|AAB17375.1| 154|Homo sapiens putative cytosolic NADP-d... 99 9e-21
BT019589-1|AAV38396.1| 311|Homo sapiens phosphatidic acid phosp... 31 6.4
AF480883-1|AAO84481.1| 311|Homo sapiens vascular endothelial gr... 31 6.4
AF043329-1|AAD02271.1| 311|Homo sapiens type-2 phosphatidic aci... 31 6.4
AF017786-1|AAC63433.1| 311|Homo sapiens phosphatidic acid phosp... 31 6.4
AB000889-1|BAA22594.1| 311|Homo sapiens phosphatidic acid phosp... 31 6.4
>CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 368 bits (906), Expect = e-101
Identities = 170/216 (78%), Positives = 186/216 (86%)
Frame = -2
Query: 803 SFKFALDXKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKXQXEDAGIWYEHRLIDDMV 624
SF+ AL +PLYLSTKNTILKKYDGRFKDIFQ+IYD++YK Q E IWYEHRLIDDMV
Sbjct: 196 SFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMV 255
Query: 623 AYAMKSEGGFVWACXNYDGDVQSDSVAQGYGSLGLXTSVLICPDGKTVEAEAAHGTVTRH 444
A AMKSEGGF+WAC NYDGDVQSDSVAQGYGSLG+ TSVL+CPDGKTVEAEAAHGTVTRH
Sbjct: 256 AQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRH 315
Query: 443 FRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALXNFAETLEKVCIETIESGIMTKD 264
+R YQ+G+ETSTNPIASIFAWTRGL HRAKLDNN L FA LE+V IETIE+G MTKD
Sbjct: 316 YRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKD 375
Query: 263 LAICIKGMNNVKRSDYYETFEFMDKLAENLXVALGQ 156
LA CIKG+ NV+RSDY TFEFMDKL ENL + L Q
Sbjct: 376 LAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQ 411
>CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 368 bits (906), Expect = e-101
Identities = 170/216 (78%), Positives = 186/216 (86%)
Frame = -2
Query: 803 SFKFALDXKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKXQXEDAGIWYEHRLIDDMV 624
SF+ AL +PLYLSTKNTILKKYDGRFKDIFQ+IYD++YK Q E IWYEHRLIDDMV
Sbjct: 196 SFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMV 255
Query: 623 AYAMKSEGGFVWACXNYDGDVQSDSVAQGYGSLGLXTSVLICPDGKTVEAEAAHGTVTRH 444
A AMKSEGGF+WAC NYDGDVQSDSVAQGYGSLG+ TSVL+CPDGKTVEAEAAHGTVTRH
Sbjct: 256 AQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRH 315
Query: 443 FRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALXNFAETLEKVCIETIESGIMTKD 264
+R YQ+G+ETSTNPIASIFAWTRGL HRAKLDNN L FA LE+V IETIE+G MTKD
Sbjct: 316 YRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKD 375
Query: 263 LAICIKGMNNVKRSDYYETFEFMDKLAENLXVALGQ 156
LA CIKG+ NV+RSDY TFEFMDKL ENL + L Q
Sbjct: 376 LAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQ 411
>BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein
protein.
Length = 414
Score = 368 bits (906), Expect = e-101
Identities = 170/216 (78%), Positives = 186/216 (86%)
Frame = -2
Query: 803 SFKFALDXKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKXQXEDAGIWYEHRLIDDMV 624
SF+ AL +PLYLSTKNTILKKYDGRFKDIFQ+IYD++YK Q E IWYEHRLIDDMV
Sbjct: 196 SFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMV 255
Query: 623 AYAMKSEGGFVWACXNYDGDVQSDSVAQGYGSLGLXTSVLICPDGKTVEAEAAHGTVTRH 444
A AMKSEGGF+WAC NYDGDVQSDSVAQGYGSLG+ TSVL+CPDGKTVEAEAAHGTVTRH
Sbjct: 256 AQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRH 315
Query: 443 FRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALXNFAETLEKVCIETIESGIMTKD 264
+R YQ+G+ETSTNPIASIFAWTRGL HRAKLDNN L FA LE+V IETIE+G MTKD
Sbjct: 316 YRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKD 375
Query: 263 LAICIKGMNNVKRSDYYETFEFMDKLAENLXVALGQ 156
LA CIKG+ NV+RSDY TFEFMDKL ENL + L Q
Sbjct: 376 LAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQ 411
>BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein.
Length = 414
Score = 368 bits (906), Expect = e-101
Identities = 170/216 (78%), Positives = 186/216 (86%)
Frame = -2
Query: 803 SFKFALDXKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKXQXEDAGIWYEHRLIDDMV 624
SF+ AL +PLYLSTKNTILKKYDGRFKDIFQ+IYD++YK Q E IWYEHRLIDDMV
Sbjct: 196 SFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMV 255
Query: 623 AYAMKSEGGFVWACXNYDGDVQSDSVAQGYGSLGLXTSVLICPDGKTVEAEAAHGTVTRH 444
A AMKSEGGF+WAC NYDGDVQSDSVAQGYGSLG+ TSVL+CPDGKTVEAEAAHGTVTRH
Sbjct: 256 AQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRH 315
Query: 443 FRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALXNFAETLEKVCIETIESGIMTKD 264
+R YQ+G+ETSTNPIASIFAWTRGL HRAKLDNN L FA LE+V IETIE+G MTKD
Sbjct: 316 YRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKD 375
Query: 263 LAICIKGMNNVKRSDYYETFEFMDKLAENLXVALGQ 156
LA CIKG+ NV+RSDY TFEFMDKL ENL + L Q
Sbjct: 376 LAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQ 411
>AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 368 bits (906), Expect = e-101
Identities = 170/216 (78%), Positives = 186/216 (86%)
Frame = -2
Query: 803 SFKFALDXKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKXQXEDAGIWYEHRLIDDMV 624
SF+ AL +PLYLSTKNTILKKYDGRFKDIFQ+IYD++YK Q E IWYEHRLIDDMV
Sbjct: 196 SFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMV 255
Query: 623 AYAMKSEGGFVWACXNYDGDVQSDSVAQGYGSLGLXTSVLICPDGKTVEAEAAHGTVTRH 444
A AMKSEGGF+WAC NYDGDVQSDSVAQGYGSLG+ TSVL+CPDGKTVEAEAAHGTVTRH
Sbjct: 256 AQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRH 315
Query: 443 FRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALXNFAETLEKVCIETIESGIMTKD 264
+R YQ+G+ETSTNPIASIFAWTRGL HRAKLDNN L FA LE+V IETIE+G MTKD
Sbjct: 316 YRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKD 375
Query: 263 LAICIKGMNNVKRSDYYETFEFMDKLAENLXVALGQ 156
LA CIKG+ NV+RSDY TFEFMDKL ENL + L Q
Sbjct: 376 LAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQ 411
>AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein.
Length = 414
Score = 368 bits (906), Expect = e-101
Identities = 170/216 (78%), Positives = 186/216 (86%)
Frame = -2
Query: 803 SFKFALDXKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKXQXEDAGIWYEHRLIDDMV 624
SF+ AL +PLYLSTKNTILKKYDGRFKDIFQ+IYD++YK Q E IWYEHRLIDDMV
Sbjct: 196 SFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMV 255
Query: 623 AYAMKSEGGFVWACXNYDGDVQSDSVAQGYGSLGLXTSVLICPDGKTVEAEAAHGTVTRH 444
A AMKSEGGF+WAC NYDGDVQSDSVAQGYGSLG+ TSVL+CPDGKTVEAEAAHGTVTRH
Sbjct: 256 AQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRH 315
Query: 443 FRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALXNFAETLEKVCIETIESGIMTKD 264
+R YQ+G+ETSTNPIASIFAWTRGL HRAKLDNN L FA LE+V IETIE+G MTKD
Sbjct: 316 YRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKD 375
Query: 263 LAICIKGMNNVKRSDYYETFEFMDKLAENLXVALGQ 156
LA CIKG+ NV+RSDY TFEFMDKL ENL + L Q
Sbjct: 376 LAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQ 411
>BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenase 1
(NADP+), soluble protein.
Length = 414
Score = 367 bits (903), Expect = e-101
Identities = 169/216 (78%), Positives = 186/216 (86%)
Frame = -2
Query: 803 SFKFALDXKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKXQXEDAGIWYEHRLIDDMV 624
SF+ AL +PLYLSTKNTILKKYDGRFKDIFQ+IYD++YK Q E IWYEHRLIDDMV
Sbjct: 196 SFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMV 255
Query: 623 AYAMKSEGGFVWACXNYDGDVQSDSVAQGYGSLGLXTSVLICPDGKTVEAEAAHGTVTRH 444
A AMKSEGGF+WAC NYDGDVQSDSVAQGYGSLG+ TSVL+CPDGKTVEAE+AHGTVTRH
Sbjct: 256 AQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAESAHGTVTRH 315
Query: 443 FRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALXNFAETLEKVCIETIESGIMTKD 264
+R YQ+G+ETSTNPIASIFAWTRGL HRAKLDNN L FA LE+V IETIE+G MTKD
Sbjct: 316 YRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKD 375
Query: 263 LAICIKGMNNVKRSDYYETFEFMDKLAENLXVALGQ 156
LA CIKG+ NV+RSDY TFEFMDKL ENL + L Q
Sbjct: 376 LAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQ 411
>CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 365 bits (899), Expect = e-101
Identities = 169/216 (78%), Positives = 185/216 (85%)
Frame = -2
Query: 803 SFKFALDXKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKXQXEDAGIWYEHRLIDDMV 624
SF+ AL +PLYLSTKNTILKKYDGRFKDIFQ+IYD++YK Q E IWYEHRLIDDMV
Sbjct: 196 SFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMV 255
Query: 623 AYAMKSEGGFVWACXNYDGDVQSDSVAQGYGSLGLXTSVLICPDGKTVEAEAAHGTVTRH 444
A AMKSEGGF+WAC NYDGDVQSDSVAQGYGSLG+ TSVL+CPDGKTVEAEAAHGTVTRH
Sbjct: 256 AQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRH 315
Query: 443 FRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALXNFAETLEKVCIETIESGIMTKD 264
+R YQ+G+ETSTNPIASIFAWTRGL HRAKLDNN L FA LE+V IETIE+G MTK
Sbjct: 316 YRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKG 375
Query: 263 LAICIKGMNNVKRSDYYETFEFMDKLAENLXVALGQ 156
LA CIKG+ NV+RSDY TFEFMDKL ENL + L Q
Sbjct: 376 LAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQ 411
>AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 360 bits (885), Expect = 4e-99
Identities = 167/216 (77%), Positives = 184/216 (85%)
Frame = -2
Query: 803 SFKFALDXKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKXQXEDAGIWYEHRLIDDMV 624
SF+ AL +PLYLSTKNTILK YDGRFKDIFQ+IYD++YK Q E IWYEHRLIDDMV
Sbjct: 196 SFQMALSKGWPLYLSTKNTILKIYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMV 255
Query: 623 AYAMKSEGGFVWACXNYDGDVQSDSVAQGYGSLGLXTSVLICPDGKTVEAEAAHGTVTRH 444
A AMKSEGGF+WAC NYDGDVQSDSVAQGYGSLG+ TSVL+CPDGKTVEAEAAHGTVTRH
Sbjct: 256 AQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRH 315
Query: 443 FRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALXNFAETLEKVCIETIESGIMTKD 264
+R YQ+G+ETSTN IASIFAWTRGL HRAKLDNN L FA LE+V IETIE+G MTKD
Sbjct: 316 YRMYQKGQETSTNLIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKD 375
Query: 263 LAICIKGMNNVKRSDYYETFEFMDKLAENLXVALGQ 156
LA CI+G+ NV+RSDY TFEFMDKL ENL + L Q
Sbjct: 376 LAACIRGLPNVQRSDYLNTFEFMDKLGENLKIKLAQ 411
>DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenase 1
protein.
Length = 371
Score = 357 bits (877), Expect = 3e-98
Identities = 164/205 (80%), Positives = 179/205 (87%)
Frame = -2
Query: 803 SFKFALDXKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKXQXEDAGIWYEHRLIDDMV 624
SF+ AL +PLYLSTKNTILKKYDGRFKDIFQ+IYD++YK Q E IWYEHRLIDDMV
Sbjct: 167 SFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMV 226
Query: 623 AYAMKSEGGFVWACXNYDGDVQSDSVAQGYGSLGLXTSVLICPDGKTVEAEAAHGTVTRH 444
A AMKSEGGF+WAC NYDGDVQSDSVAQGYGSLG+ TSVL+CPDGKTVEAEAAHGTVTRH
Sbjct: 227 AQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRH 286
Query: 443 FRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALXNFAETLEKVCIETIESGIMTKD 264
+R YQ+G+ETSTNPIASIFAWTRGL HRAKLDNN L FA LE+V IETIE+G MTKD
Sbjct: 287 YRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKD 346
Query: 263 LAICIKGMNNVKRSDYYETFEFMDK 189
LA CIKG+ NV+RSDY TFEFMDK
Sbjct: 347 LAACIKGLPNVQRSDYLNTFEFMDK 371
>X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase
(NADP+) protein.
Length = 452
Score = 327 bits (804), Expect = 2e-89
Identities = 147/216 (68%), Positives = 178/216 (82%), Gaps = 1/216 (0%)
Frame = -2
Query: 800 FKFALDXKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKXQXEDAGIWYEHRLIDDMVA 621
F++A+ K+PLY+STKNTILK YDGRFKDIFQ+I+D+ YK + IWYEHRLIDDMVA
Sbjct: 236 FQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVA 295
Query: 620 YAMKSEGGFVWACXNYDGDVQSDSVAQGYGSLGLXTSVLICPDGKTVEAEAAHGTVTRHF 441
+KS GGFVWAC NYDGDVQSD +AQG+GSLGL TSVL+CPDGKT+EAEAAHGTVTRH+
Sbjct: 296 QVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHY 355
Query: 440 RFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALXNFAETLEKVCIETIESGIMTKDL 261
R +Q+G+ TSTNPIASIFAWTRGL HR KLD N L FA+ LEKVC+ET+ESG MTKDL
Sbjct: 356 REHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDL 415
Query: 260 AICIKGMNNVKRSDYY-ETFEFMDKLAENLXVALGQ 156
A CI G++NVK ++++ T +F+D + NL ALG+
Sbjct: 416 AGCIHGLSNVKLNEHFLNTMDFLDTIKSNLDRALGR 451
>U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase
protein.
Length = 419
Score = 326 bits (802), Expect = 4e-89
Identities = 147/216 (68%), Positives = 178/216 (82%), Gaps = 1/216 (0%)
Frame = -2
Query: 800 FKFALDXKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKXQXEDAGIWYEHRLIDDMVA 621
F++A+ K+PLY+STKNTILK YDGRFKDIFQ+I+D+ YK + IWYEHRLIDDMVA
Sbjct: 203 FQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVA 262
Query: 620 YAMKSEGGFVWACXNYDGDVQSDSVAQGYGSLGLXTSVLICPDGKTVEAEAAHGTVTRHF 441
+KS GGFVWAC NYDGDVQSD +AQG+GSLGL TSVL+CPDGKT+EAEAAHGTVTRH+
Sbjct: 263 QVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHY 322
Query: 440 RFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALXNFAETLEKVCIETIESGIMTKDL 261
R +Q+G+ TSTNPIASIFAWTRGL HR KLD N L FA+ LEKVC+ET+ESG MTKDL
Sbjct: 323 REHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDL 382
Query: 260 AICIKGMNNVKRSDYY-ETFEFMDKLAENLXVALGQ 156
A CI G++NVK ++++ T +F+D + NL ALG+
Sbjct: 383 AGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGR 418
>BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 326 bits (802), Expect = 4e-89
Identities = 147/216 (68%), Positives = 178/216 (82%), Gaps = 1/216 (0%)
Frame = -2
Query: 800 FKFALDXKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKXQXEDAGIWYEHRLIDDMVA 621
F++A+ K+PLY+STKNTILK YDGRFKDIFQ+I+D+ YK + IWYEHRLIDDMVA
Sbjct: 236 FQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVA 295
Query: 620 YAMKSEGGFVWACXNYDGDVQSDSVAQGYGSLGLXTSVLICPDGKTVEAEAAHGTVTRHF 441
+KS GGFVWAC NYDGDVQSD +AQG+GSLGL TSVL+CPDGKT+EAEAAHGTVTRH+
Sbjct: 296 QVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHY 355
Query: 440 RFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALXNFAETLEKVCIETIESGIMTKDL 261
R +Q+G+ TSTNPIASIFAWTRGL HR KLD N L FA+ LEKVC+ET+ESG MTKDL
Sbjct: 356 REHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDL 415
Query: 260 AICIKGMNNVKRSDYY-ETFEFMDKLAENLXVALGQ 156
A CI G++NVK ++++ T +F+D + NL ALG+
Sbjct: 416 AGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGR 451
>BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 326 bits (802), Expect = 4e-89
Identities = 147/216 (68%), Positives = 178/216 (82%), Gaps = 1/216 (0%)
Frame = -2
Query: 800 FKFALDXKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKXQXEDAGIWYEHRLIDDMVA 621
F++A+ K+PLY+STKNTILK YDGRFKDIFQ+I+D+ YK + IWYEHRLIDDMVA
Sbjct: 236 FQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVA 295
Query: 620 YAMKSEGGFVWACXNYDGDVQSDSVAQGYGSLGLXTSVLICPDGKTVEAEAAHGTVTRHF 441
+KS GGFVWAC NYDGDVQSD +AQG+GSLGL TSVL+CPDGKT+EAEAAHGTVTRH+
Sbjct: 296 QVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHY 355
Query: 440 RFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALXNFAETLEKVCIETIESGIMTKDL 261
R +Q+G+ TSTNPIASIFAWTRGL HR KLD N L FA+ LEKVC+ET+ESG MTKDL
Sbjct: 356 REHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDL 415
Query: 260 AICIKGMNNVKRSDYY-ETFEFMDKLAENLXVALGQ 156
A CI G++NVK ++++ T +F+D + NL ALG+
Sbjct: 416 AGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGR 451
>AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial precursor variant protein.
Length = 452
Score = 325 bits (798), Expect = 1e-88
Identities = 146/216 (67%), Positives = 178/216 (82%), Gaps = 1/216 (0%)
Frame = -2
Query: 800 FKFALDXKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKXQXEDAGIWYEHRLIDDMVA 621
F++A+ K+PLY+STKNTILK YDGRFKDIFQ+I+D+ Y+ + IWYEHRLIDDMVA
Sbjct: 236 FQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYETDFDKNKIWYEHRLIDDMVA 295
Query: 620 YAMKSEGGFVWACXNYDGDVQSDSVAQGYGSLGLXTSVLICPDGKTVEAEAAHGTVTRHF 441
+KS GGFVWAC NYDGDVQSD +AQG+GSLGL TSVL+CPDGKT+EAEAAHGTVTRH+
Sbjct: 296 QVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHY 355
Query: 440 RFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALXNFAETLEKVCIETIESGIMTKDL 261
R +Q+G+ TSTNPIASIFAWTRGL HR KLD N L FA+ LEKVC+ET+ESG MTKDL
Sbjct: 356 REHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDL 415
Query: 260 AICIKGMNNVKRSDYY-ETFEFMDKLAENLXVALGQ 156
A CI G++NVK ++++ T +F+D + NL ALG+
Sbjct: 416 AGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGR 451
>AF197566-1|AAG43470.1| 127|Homo sapiens NADP+-specific isocitrate
dehydrogenase protein.
Length = 127
Score = 126 bits (303), Expect = 1e-28
Identities = 60/89 (67%), Positives = 68/89 (76%)
Frame = -2
Query: 422 KETSTNPIASIFAWTRGLLHRAKLDNNDALXNFAETLEKVCIETIESGIMTKDLAICIKG 243
+E STNPIASIFAWTRGL RAK DNN L FA LE+VCIETIE+G MTKDLA CIKG
Sbjct: 1 QEISTNPIASIFAWTRGLALRAKTDNNKELAFFANALEEVCIETIEAGFMTKDLAACIKG 60
Query: 242 MNNVKRSDYYETFEFMDKLAENLXVALGQ 156
+ + + SDY TFEFM+KL ENL + L Q
Sbjct: 61 LPSAQCSDYLNTFEFMEKLGENLKIKLAQ 89
>U62389-1|AAB17375.1| 154|Homo sapiens putative cytosolic
NADP-dependent isocitrate dehydrogenase protein.
Length = 154
Score = 99 bits (238), Expect = 9e-21
Identities = 44/58 (75%), Positives = 49/58 (84%)
Frame = -2
Query: 803 SFKFALDXKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKXQXEDAGIWYEHRLIDD 630
SF+ AL +PLYLSTKNTILKKYDGRFKDIFQ+IYD++YK Q E IWYEHRLIDD
Sbjct: 97 SFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDD 154
>BT019589-1|AAV38396.1| 311|Homo sapiens phosphatidic acid
phosphatase type 2B protein.
Length = 311
Score = 30.7 bits (66), Expect = 6.4
Identities = 29/95 (30%), Positives = 38/95 (40%), Gaps = 2/95 (2%)
Frame = -3
Query: 592 SGPAKIMMETYNLIVL-LRAMGHWASXHLFSFVLMAKQLRLKLPMALLHVISDSISKEKR 416
SG A M T +VL L+A W L + L+ L M + +S K
Sbjct: 197 SGHASFSMYTMLYLVLYLQARFTWRGARL-----LRPLLQFTLIMMAFYTGLSRVSDHKH 251
Query: 415 HPPIQLLQFLLG-LEVCCIVLN*TTMMPXRTLLRL 314
HP L F G L CCIV + + +T L L
Sbjct: 252 HPSDVLAGFAQGALVACCIVFFVSDLFKTKTTLSL 286
>AF480883-1|AAO84481.1| 311|Homo sapiens vascular endothelial
growth factor and type I collagen inducible protein
protein.
Length = 311
Score = 30.7 bits (66), Expect = 6.4
Identities = 29/95 (30%), Positives = 38/95 (40%), Gaps = 2/95 (2%)
Frame = -3
Query: 592 SGPAKIMMETYNLIVL-LRAMGHWASXHLFSFVLMAKQLRLKLPMALLHVISDSISKEKR 416
SG A M T +VL L+A W L + L+ L M + +S K
Sbjct: 197 SGHASFSMYTMLYLVLYLQARFTWRGARL-----LRPLLQFTLIMMAFYTGLSRVSDHKH 251
Query: 415 HPPIQLLQFLLG-LEVCCIVLN*TTMMPXRTLLRL 314
HP L F G L CCIV + + +T L L
Sbjct: 252 HPSDVLAGFAQGALVACCIVFFVSDLFKTKTTLSL 286
>AF043329-1|AAD02271.1| 311|Homo sapiens type-2 phosphatidic acid
phosphatase-beta protein.
Length = 311
Score = 30.7 bits (66), Expect = 6.4
Identities = 29/95 (30%), Positives = 38/95 (40%), Gaps = 2/95 (2%)
Frame = -3
Query: 592 SGPAKIMMETYNLIVL-LRAMGHWASXHLFSFVLMAKQLRLKLPMALLHVISDSISKEKR 416
SG A M T +VL L+A W L + L+ L M + +S K
Sbjct: 197 SGHASFSMYTMLYLVLYLQARFTWRGARL-----LRPLLQFTLIMMAFYTGLSRVSDHKH 251
Query: 415 HPPIQLLQFLLG-LEVCCIVLN*TTMMPXRTLLRL 314
HP L F G L CCIV + + +T L L
Sbjct: 252 HPSDVLAGFAQGALVACCIVFFVSDLFKTKTTLSL 286
>AF017786-1|AAC63433.1| 311|Homo sapiens phosphatidic acid
phosphohydrolase homolog protein.
Length = 311
Score = 30.7 bits (66), Expect = 6.4
Identities = 29/95 (30%), Positives = 38/95 (40%), Gaps = 2/95 (2%)
Frame = -3
Query: 592 SGPAKIMMETYNLIVL-LRAMGHWASXHLFSFVLMAKQLRLKLPMALLHVISDSISKEKR 416
SG A M T +VL L+A W L + L+ L M + +S K
Sbjct: 197 SGHASFSMYTMLYLVLYLQARFTWRGARL-----LRPLLQFTLIMMAFYTGLSRVSDHKH 251
Query: 415 HPPIQLLQFLLG-LEVCCIVLN*TTMMPXRTLLRL 314
HP L F G L CCIV + + +T L L
Sbjct: 252 HPSDVLAGFAQGALVACCIVFFVSDLFKTKTTLSL 286
>AB000889-1|BAA22594.1| 311|Homo sapiens phosphatidic acid
phosphatase 2b protein.
Length = 311
Score = 30.7 bits (66), Expect = 6.4
Identities = 29/95 (30%), Positives = 38/95 (40%), Gaps = 2/95 (2%)
Frame = -3
Query: 592 SGPAKIMMETYNLIVL-LRAMGHWASXHLFSFVLMAKQLRLKLPMALLHVISDSISKEKR 416
SG A M T +VL L+A W L + L+ L M + +S K
Sbjct: 197 SGHASFSMYTMLYLVLYLQARFTWRGARL-----LRPLLQFTLIMMAFYTGLSRVSDHKH 251
Query: 415 HPPIQLLQFLLG-LEVCCIVLN*TTMMPXRTLLRL 314
HP L F G L CCIV + + +T L L
Sbjct: 252 HPSDVLAGFAQGALVACCIVFFVSDLFKTKTTLSL 286
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 105,646,639
Number of Sequences: 237096
Number of extensions: 2021612
Number of successful extensions: 3002
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 2913
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2997
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9924838204
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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