Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P08_pT_C01
(792 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M23294-1|AAA52645.1| 556|Homo sapiens beta-hexosaminidase beta-... 181 2e-45
M19735-1|AAA68620.1| 544|Homo sapiens beta-hexosaminidase beta-... 181 2e-45
M13519-1|AAA51828.1| 572|Homo sapiens HEXB protein. 181 2e-45
BT009919-1|AAP88921.1| 556|Homo sapiens hexosaminidase B (beta ... 181 2e-45
BC017378-1|AAH17378.1| 556|Homo sapiens hexosaminidase B (beta ... 181 2e-45
AY643499-1|AAV48875.1| 331|Homo sapiens ENC-1AS protein. 181 2e-45
AF378118-1|AAM46114.1| 556|Homo sapiens cervical cancer proto-o... 181 2e-45
S62076-1|AAD13932.1| 529|Homo sapiens HEXA protein. 174 3e-43
M16424-1|AAB00965.1| 529|Homo sapiens HEXA protein. 174 3e-43
M13520-1|AAA51827.1| 490|Homo sapiens HEXA protein. 174 3e-43
BC084537-1|AAH84537.1| 529|Homo sapiens hexosaminidase A (alpha... 174 3e-43
BC021030-1|AAH21030.1| 309|Homo sapiens HEXA protein protein. 174 3e-43
BC018927-1|AAH18927.1| 529|Homo sapiens hexosaminidase A (alpha... 174 3e-43
BC001138-1|AAH01138.2| 409|Homo sapiens HEXA protein protein. 174 3e-43
AK222502-1|BAD96222.1| 529|Homo sapiens hexosaminidase A prepro... 172 1e-42
>M23294-1|AAA52645.1| 556|Homo sapiens beta-hexosaminidase
beta-subunit protein.
Length = 556
Score = 181 bits (441), Expect = 2e-45
Identities = 88/239 (36%), Positives = 142/239 (59%), Gaps = 6/239 (2%)
Frame = -2
Query: 791 NPIRSTTYXILGELIREVQNLFPDRYYHVGGDEVDLSCWQSNPELKEYMKQHNLTAN--G 618
NP +TTY L +E+ +FPD++ H+GGDEV+ CW+SNP+++++M+Q +
Sbjct: 323 NPTLNTTYSFLTTFFKEISEVFPDQFIHLGGDEVEFKCWESNPKIQDFMRQKGFGTDFKK 382
Query: 617 VHAMFMKEVIGRVKKTTV-PIVWQEVYDEKVPISKDTLIQVWK-YKWIDEMIKILNSGHK 444
+ + ++++V+ + IVWQEV+D+K ++ T+++VWK + +E+ ++ SG
Sbjct: 383 LESFYIQKVLDIIATINKGSIVWQEVFDDKAKLAPGTIVEVWKDSAYPEELSRVTASGFP 442
Query: 443 VVFSSSWYLDYLNF--NWNSFYGDDPRLMVYQKKKNARLENIVGGEACMWGEMADDTNVI 270
V+ S+ WYLD +++ +W +Y +P L +K +L +GGEAC+WGE D TN+
Sbjct: 443 VILSAPWYLDLISYGQDWRKYYKVEP-LDFGGTQKQKQL--FIGGEACLWGEYVDATNLT 499
Query: 269 SRTWPRTSAVAERLWSGLDYKHPPKDPVTIHVRQRIEEHTCRMLRRGIAAEPPNGPGFC 93
R WPR SAV ERLWS D + R+ H CRM+ RGIAA+P G+C
Sbjct: 500 PRLWPRASAVGERLWSSKDVRDMD------DAYDRLTRHRCRMVERGIAAQPLYA-GYC 551
>M19735-1|AAA68620.1| 544|Homo sapiens beta-hexosaminidase
beta-subunit protein.
Length = 544
Score = 181 bits (441), Expect = 2e-45
Identities = 88/239 (36%), Positives = 142/239 (59%), Gaps = 6/239 (2%)
Frame = -2
Query: 791 NPIRSTTYXILGELIREVQNLFPDRYYHVGGDEVDLSCWQSNPELKEYMKQHNLTAN--G 618
NP +TTY L +E+ +FPD++ H+GGDEV+ CW+SNP+++++M+Q +
Sbjct: 311 NPTLNTTYSFLTTFFKEISEVFPDQFIHLGGDEVEFKCWESNPKIQDFMRQKGFGTDFKK 370
Query: 617 VHAMFMKEVIGRVKKTTV-PIVWQEVYDEKVPISKDTLIQVWK-YKWIDEMIKILNSGHK 444
+ + ++++V+ + IVWQEV+D+K ++ T+++VWK + +E+ ++ SG
Sbjct: 371 LESFYIQKVLDIIATINKGSIVWQEVFDDKAKLAPGTIVEVWKDSAYPEELSRVTASGFP 430
Query: 443 VVFSSSWYLDYLNF--NWNSFYGDDPRLMVYQKKKNARLENIVGGEACMWGEMADDTNVI 270
V+ S+ WYLD +++ +W +Y +P L +K +L +GGEAC+WGE D TN+
Sbjct: 431 VILSAPWYLDLISYGQDWRKYYKVEP-LDFGGTQKQKQL--FIGGEACLWGEYVDATNLT 487
Query: 269 SRTWPRTSAVAERLWSGLDYKHPPKDPVTIHVRQRIEEHTCRMLRRGIAAEPPNGPGFC 93
R WPR SAV ERLWS D + R+ H CRM+ RGIAA+P G+C
Sbjct: 488 PRLWPRASAVGERLWSSKDVRDMD------DAYDRLTRHRCRMVERGIAAQPLYA-GYC 539
>M13519-1|AAA51828.1| 572|Homo sapiens HEXB protein.
Length = 572
Score = 181 bits (441), Expect = 2e-45
Identities = 88/239 (36%), Positives = 142/239 (59%), Gaps = 6/239 (2%)
Frame = -2
Query: 791 NPIRSTTYXILGELIREVQNLFPDRYYHVGGDEVDLSCWQSNPELKEYMKQHNLTAN--G 618
NP +TTY L +E+ +FPD++ H+GGDEV+ CW+SNP+++++M+Q +
Sbjct: 339 NPTLNTTYSFLTTFFKEISEVFPDQFIHLGGDEVEFKCWESNPKIQDFMRQKGFGTDFKK 398
Query: 617 VHAMFMKEVIGRVKKTTV-PIVWQEVYDEKVPISKDTLIQVWK-YKWIDEMIKILNSGHK 444
+ + ++++V+ + IVWQEV+D+K ++ T+++VWK + +E+ ++ SG
Sbjct: 399 LESFYIQKVLDIIATINKGSIVWQEVFDDKAKLAPGTIVEVWKDSAYPEELSRVTASGFP 458
Query: 443 VVFSSSWYLDYLNF--NWNSFYGDDPRLMVYQKKKNARLENIVGGEACMWGEMADDTNVI 270
V+ S+ WYLD +++ +W +Y +P L +K +L +GGEAC+WGE D TN+
Sbjct: 459 VILSAPWYLDLISYGQDWRKYYKVEP-LDFGGTQKQKQL--FIGGEACLWGEYVDATNLT 515
Query: 269 SRTWPRTSAVAERLWSGLDYKHPPKDPVTIHVRQRIEEHTCRMLRRGIAAEPPNGPGFC 93
R WPR SAV ERLWS D + R+ H CRM+ RGIAA+P G+C
Sbjct: 516 PRLWPRASAVGERLWSSKDVRDMD------DAYDRLTRHRCRMVERGIAAQPLYA-GYC 567
>BT009919-1|AAP88921.1| 556|Homo sapiens hexosaminidase B (beta
polypeptide) protein.
Length = 556
Score = 181 bits (441), Expect = 2e-45
Identities = 88/239 (36%), Positives = 142/239 (59%), Gaps = 6/239 (2%)
Frame = -2
Query: 791 NPIRSTTYXILGELIREVQNLFPDRYYHVGGDEVDLSCWQSNPELKEYMKQHNLTAN--G 618
NP +TTY L +E+ +FPD++ H+GGDEV+ CW+SNP+++++M+Q +
Sbjct: 323 NPTLNTTYSFLTTFFKEISEVFPDQFIHLGGDEVEFKCWESNPKIQDFMRQKGFGTDFKK 382
Query: 617 VHAMFMKEVIGRVKKTTV-PIVWQEVYDEKVPISKDTLIQVWK-YKWIDEMIKILNSGHK 444
+ + ++++V+ + IVWQEV+D+K ++ T+++VWK + +E+ ++ SG
Sbjct: 383 LESFYIQKVLDIIATINKGSIVWQEVFDDKAKLAPGTIVEVWKDSAYPEELSRVTASGFP 442
Query: 443 VVFSSSWYLDYLNF--NWNSFYGDDPRLMVYQKKKNARLENIVGGEACMWGEMADDTNVI 270
V+ S+ WYLD +++ +W +Y +P L +K +L +GGEAC+WGE D TN+
Sbjct: 443 VILSAPWYLDLISYGQDWRKYYKVEP-LDFGGTQKQKQL--FIGGEACLWGEYVDATNLT 499
Query: 269 SRTWPRTSAVAERLWSGLDYKHPPKDPVTIHVRQRIEEHTCRMLRRGIAAEPPNGPGFC 93
R WPR SAV ERLWS D + R+ H CRM+ RGIAA+P G+C
Sbjct: 500 PRLWPRASAVGERLWSSKDVRDMD------DAYDRLTRHRCRMVERGIAAQPLYA-GYC 551
>BC017378-1|AAH17378.1| 556|Homo sapiens hexosaminidase B (beta
polypeptide) protein.
Length = 556
Score = 181 bits (441), Expect = 2e-45
Identities = 88/239 (36%), Positives = 142/239 (59%), Gaps = 6/239 (2%)
Frame = -2
Query: 791 NPIRSTTYXILGELIREVQNLFPDRYYHVGGDEVDLSCWQSNPELKEYMKQHNLTAN--G 618
NP +TTY L +E+ +FPD++ H+GGDEV+ CW+SNP+++++M+Q +
Sbjct: 323 NPTLNTTYSFLTTFFKEISEVFPDQFIHLGGDEVEFKCWESNPKIQDFMRQKGFGTDFKK 382
Query: 617 VHAMFMKEVIGRVKKTTV-PIVWQEVYDEKVPISKDTLIQVWK-YKWIDEMIKILNSGHK 444
+ + ++++V+ + IVWQEV+D+K ++ T+++VWK + +E+ ++ SG
Sbjct: 383 LESFYIQKVLDIIATINKGSIVWQEVFDDKAKLAPGTIVEVWKDSAYPEELSRVTASGFP 442
Query: 443 VVFSSSWYLDYLNF--NWNSFYGDDPRLMVYQKKKNARLENIVGGEACMWGEMADDTNVI 270
V+ S+ WYLD +++ +W +Y +P L +K +L +GGEAC+WGE D TN+
Sbjct: 443 VILSAPWYLDLISYGQDWRKYYKVEP-LDFGGTQKQKQL--FIGGEACLWGEYVDATNLT 499
Query: 269 SRTWPRTSAVAERLWSGLDYKHPPKDPVTIHVRQRIEEHTCRMLRRGIAAEPPNGPGFC 93
R WPR SAV ERLWS D + R+ H CRM+ RGIAA+P G+C
Sbjct: 500 PRLWPRASAVGERLWSSKDVRDMD------DAYDRLTRHRCRMVERGIAAQPLYA-GYC 551
>AY643499-1|AAV48875.1| 331|Homo sapiens ENC-1AS protein.
Length = 331
Score = 181 bits (441), Expect = 2e-45
Identities = 88/239 (36%), Positives = 142/239 (59%), Gaps = 6/239 (2%)
Frame = -2
Query: 791 NPIRSTTYXILGELIREVQNLFPDRYYHVGGDEVDLSCWQSNPELKEYMKQHNLTAN--G 618
NP +TTY L +E+ +FPD++ H+GGDEV+ CW+SNP+++++M+Q +
Sbjct: 98 NPTLNTTYSFLTTFFKEISEVFPDQFIHLGGDEVEFKCWESNPKIQDFMRQKGFGTDFKK 157
Query: 617 VHAMFMKEVIGRVKKTTV-PIVWQEVYDEKVPISKDTLIQVWK-YKWIDEMIKILNSGHK 444
+ + ++++V+ + IVWQEV+D+K ++ T+++VWK + +E+ ++ SG
Sbjct: 158 LESFYIQKVLDIIATINKGSIVWQEVFDDKAKLAPGTIVEVWKDSAYPEELSRVTASGFP 217
Query: 443 VVFSSSWYLDYLNF--NWNSFYGDDPRLMVYQKKKNARLENIVGGEACMWGEMADDTNVI 270
V+ S+ WYLD +++ +W +Y +P L +K +L +GGEAC+WGE D TN+
Sbjct: 218 VILSAPWYLDLISYGQDWRKYYKVEP-LDFGGTQKQKQL--FIGGEACLWGEYVDATNLT 274
Query: 269 SRTWPRTSAVAERLWSGLDYKHPPKDPVTIHVRQRIEEHTCRMLRRGIAAEPPNGPGFC 93
R WPR SAV ERLWS D + R+ H CRM+ RGIAA+P G+C
Sbjct: 275 PRLWPRASAVGERLWSSKDVRDMD------DAYDRLTRHRCRMVERGIAAQPLYA-GYC 326
>AF378118-1|AAM46114.1| 556|Homo sapiens cervical cancer
proto-oncogene 7 protein.
Length = 556
Score = 181 bits (441), Expect = 2e-45
Identities = 88/239 (36%), Positives = 142/239 (59%), Gaps = 6/239 (2%)
Frame = -2
Query: 791 NPIRSTTYXILGELIREVQNLFPDRYYHVGGDEVDLSCWQSNPELKEYMKQHNLTAN--G 618
NP +TTY L +E+ +FPD++ H+GGDEV+ CW+SNP+++++M+Q +
Sbjct: 323 NPTLNTTYSFLTTFFKEISEVFPDQFIHLGGDEVEFKCWESNPKIQDFMRQKGFGTDFKK 382
Query: 617 VHAMFMKEVIGRVKKTTV-PIVWQEVYDEKVPISKDTLIQVWK-YKWIDEMIKILNSGHK 444
+ + ++++V+ + IVWQEV+D+K ++ T+++VWK + +E+ ++ SG
Sbjct: 383 LESFYIQKVLDIIATINKGSIVWQEVFDDKAKLAPGTIVEVWKDSAYPEELSRVTASGFP 442
Query: 443 VVFSSSWYLDYLNF--NWNSFYGDDPRLMVYQKKKNARLENIVGGEACMWGEMADDTNVI 270
V+ S+ WYLD +++ +W +Y +P L +K +L +GGEAC+WGE D TN+
Sbjct: 443 VILSAPWYLDLISYGQDWRKYYKVEP-LDFGGTQKQKQL--FIGGEACLWGEYVDATNLT 499
Query: 269 SRTWPRTSAVAERLWSGLDYKHPPKDPVTIHVRQRIEEHTCRMLRRGIAAEPPNGPGFC 93
R WPR SAV ERLWS D + R+ H CRM+ RGIAA+P G+C
Sbjct: 500 PRLWPRASAVGERLWSSKDVRDMD------DAYDRLTRHRCRMVERGIAAQPLYA-GYC 551
>S62076-1|AAD13932.1| 529|Homo sapiens HEXA protein.
Length = 529
Score = 174 bits (424), Expect = 3e-43
Identities = 88/242 (36%), Positives = 141/242 (58%), Gaps = 9/242 (3%)
Frame = -2
Query: 791 NPIRSTTYXILGELIREVQNLFPDRYYHVGGDEVDLSCWQSNPELKEYMKQHNLTAN--G 618
NP + TY + EV ++FPD Y H+GGDEVD +CW+SNPE++++M++ +
Sbjct: 291 NPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDFTCWKSNPEIQDFMRKKGFGEDFKQ 350
Query: 617 VHAMFMKEVIGRVKKTTVP-IVWQEVYDEKVPISKDTLIQVWK----YKWIDEMIKILNS 453
+ + +++ ++ V +VWQEV+D KV I DT+IQVW+ ++ E+ + +
Sbjct: 351 LESFYIQTLLDIVSSYGKGYVVWQEVFDNKVKIQPDTIIQVWREDIPVNYMKELELVTKA 410
Query: 452 GHKVVFSSSWYLDYLNF--NWNSFYGDDPRLMVYQKKKNARLENIVGGEACMWGEMADDT 279
G + + S+ WYL+ +++ +W FY +P ++ A ++GGEACMWGE D+T
Sbjct: 411 GFRALLSAPWYLNRISYGPDWKDFYVVEPLAFEGTPEQKAL---VIGGEACMWGEYVDNT 467
Query: 278 NVISRTWPRTSAVAERLWSGLDYKHPPKDPVTIHVRQRIEEHTCRMLRRGIAAEPPNGPG 99
N++ R WPR AVAERLWS + +T +R+ C +LRRG+ A+P N G
Sbjct: 468 NLVPRLWPRAGAVAERLWS-----NKLTSDLTF-AYERLSHFRCELLRRGVQAQPLN-VG 520
Query: 98 FC 93
FC
Sbjct: 521 FC 522
>M16424-1|AAB00965.1| 529|Homo sapiens HEXA protein.
Length = 529
Score = 174 bits (424), Expect = 3e-43
Identities = 88/242 (36%), Positives = 141/242 (58%), Gaps = 9/242 (3%)
Frame = -2
Query: 791 NPIRSTTYXILGELIREVQNLFPDRYYHVGGDEVDLSCWQSNPELKEYMKQHNLTAN--G 618
NP + TY + EV ++FPD Y H+GGDEVD +CW+SNPE++++M++ +
Sbjct: 291 NPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDFTCWKSNPEIQDFMRKKGFGEDFKQ 350
Query: 617 VHAMFMKEVIGRVKKTTVP-IVWQEVYDEKVPISKDTLIQVWK----YKWIDEMIKILNS 453
+ + +++ ++ V +VWQEV+D KV I DT+IQVW+ ++ E+ + +
Sbjct: 351 LESFYIQTLLDIVSSYGKGYVVWQEVFDNKVKIQPDTIIQVWREDIPVNYMKELELVTKA 410
Query: 452 GHKVVFSSSWYLDYLNF--NWNSFYGDDPRLMVYQKKKNARLENIVGGEACMWGEMADDT 279
G + + S+ WYL+ +++ +W FY +P ++ A ++GGEACMWGE D+T
Sbjct: 411 GFRALLSAPWYLNRISYGPDWKDFYVVEPLAFEGTPEQKAL---VIGGEACMWGEYVDNT 467
Query: 278 NVISRTWPRTSAVAERLWSGLDYKHPPKDPVTIHVRQRIEEHTCRMLRRGIAAEPPNGPG 99
N++ R WPR AVAERLWS + +T +R+ C +LRRG+ A+P N G
Sbjct: 468 NLVPRLWPRAGAVAERLWS-----NKLTSDLTF-AYERLSHFRCELLRRGVQAQPLN-VG 520
Query: 98 FC 93
FC
Sbjct: 521 FC 522
>M13520-1|AAA51827.1| 490|Homo sapiens HEXA protein.
Length = 490
Score = 174 bits (424), Expect = 3e-43
Identities = 88/242 (36%), Positives = 141/242 (58%), Gaps = 9/242 (3%)
Frame = -2
Query: 791 NPIRSTTYXILGELIREVQNLFPDRYYHVGGDEVDLSCWQSNPELKEYMKQHNLTAN--G 618
NP + TY + EV ++FPD Y H+GGDEVD +CW+SNPE++++M++ +
Sbjct: 252 NPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDFTCWKSNPEIQDFMRKKGFGEDFKQ 311
Query: 617 VHAMFMKEVIGRVKKTTVP-IVWQEVYDEKVPISKDTLIQVWK----YKWIDEMIKILNS 453
+ + +++ ++ V +VWQEV+D KV I DT+IQVW+ ++ E+ + +
Sbjct: 312 LESFYIQTLLDIVSSYGKGYVVWQEVFDNKVKIQPDTIIQVWREDIPVNYMKELELVTKA 371
Query: 452 GHKVVFSSSWYLDYLNF--NWNSFYGDDPRLMVYQKKKNARLENIVGGEACMWGEMADDT 279
G + + S+ WYL+ +++ +W FY +P ++ A ++GGEACMWGE D+T
Sbjct: 372 GFRALLSAPWYLNRISYGPDWKDFYVVEPLAFEGTPEQKAL---VIGGEACMWGEYVDNT 428
Query: 278 NVISRTWPRTSAVAERLWSGLDYKHPPKDPVTIHVRQRIEEHTCRMLRRGIAAEPPNGPG 99
N++ R WPR AVAERLWS + +T +R+ C +LRRG+ A+P N G
Sbjct: 429 NLVPRLWPRAGAVAERLWS-----NKLTSDLTF-AYERLSHFRCELLRRGVQAQPLN-VG 481
Query: 98 FC 93
FC
Sbjct: 482 FC 483
>BC084537-1|AAH84537.1| 529|Homo sapiens hexosaminidase A (alpha
polypeptide) protein.
Length = 529
Score = 174 bits (424), Expect = 3e-43
Identities = 88/242 (36%), Positives = 141/242 (58%), Gaps = 9/242 (3%)
Frame = -2
Query: 791 NPIRSTTYXILGELIREVQNLFPDRYYHVGGDEVDLSCWQSNPELKEYMKQHNLTAN--G 618
NP + TY + EV ++FPD Y H+GGDEVD +CW+SNPE++++M++ +
Sbjct: 291 NPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDFTCWKSNPEIQDFMRKKGFGEDFKQ 350
Query: 617 VHAMFMKEVIGRVKKTTVP-IVWQEVYDEKVPISKDTLIQVWK----YKWIDEMIKILNS 453
+ + +++ ++ V +VWQEV+D KV I DT+IQVW+ ++ E+ + +
Sbjct: 351 LESFYIQTLLDIVSSYGKGYVVWQEVFDNKVKIQPDTIIQVWREDIPVNYMKELELVTKA 410
Query: 452 GHKVVFSSSWYLDYLNF--NWNSFYGDDPRLMVYQKKKNARLENIVGGEACMWGEMADDT 279
G + + S+ WYL+ +++ +W FY +P ++ A ++GGEACMWGE D+T
Sbjct: 411 GFRALLSAPWYLNRISYGPDWKDFYVVEPLAFEGTPEQKAL---VIGGEACMWGEYVDNT 467
Query: 278 NVISRTWPRTSAVAERLWSGLDYKHPPKDPVTIHVRQRIEEHTCRMLRRGIAAEPPNGPG 99
N++ R WPR AVAERLWS + +T +R+ C +LRRG+ A+P N G
Sbjct: 468 NLVPRLWPRAGAVAERLWS-----NKLTSDLTF-AYERLSHFRCELLRRGVQAQPLN-VG 520
Query: 98 FC 93
FC
Sbjct: 521 FC 522
>BC021030-1|AAH21030.1| 309|Homo sapiens HEXA protein protein.
Length = 309
Score = 174 bits (424), Expect = 3e-43
Identities = 88/242 (36%), Positives = 141/242 (58%), Gaps = 9/242 (3%)
Frame = -2
Query: 791 NPIRSTTYXILGELIREVQNLFPDRYYHVGGDEVDLSCWQSNPELKEYMKQHNLTAN--G 618
NP + TY + EV ++FPD Y H+GGDEVD +CW+SNPE++++M++ +
Sbjct: 71 NPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDFTCWKSNPEIQDFMRKKGFGEDFKQ 130
Query: 617 VHAMFMKEVIGRVKKTTVP-IVWQEVYDEKVPISKDTLIQVWK----YKWIDEMIKILNS 453
+ + +++ ++ V +VWQEV+D KV I DT+IQVW+ ++ E+ + +
Sbjct: 131 LESFYIQTLLDIVSSYGKGYVVWQEVFDNKVKIQPDTIIQVWREDIPVNYMKELELVTKA 190
Query: 452 GHKVVFSSSWYLDYLNF--NWNSFYGDDPRLMVYQKKKNARLENIVGGEACMWGEMADDT 279
G + + S+ WYL+ +++ +W FY +P ++ A ++GGEACMWGE D+T
Sbjct: 191 GFRALLSAPWYLNRISYGPDWKDFYVVEPLAFEGTPEQKAL---VIGGEACMWGEYVDNT 247
Query: 278 NVISRTWPRTSAVAERLWSGLDYKHPPKDPVTIHVRQRIEEHTCRMLRRGIAAEPPNGPG 99
N++ R WPR AVAERLWS + +T +R+ C +LRRG+ A+P N G
Sbjct: 248 NLVPRLWPRAGAVAERLWS-----NKLTSDLTF-AYERLSHFRCELLRRGVQAQPLN-VG 300
Query: 98 FC 93
FC
Sbjct: 301 FC 302
>BC018927-1|AAH18927.1| 529|Homo sapiens hexosaminidase A (alpha
polypeptide) protein.
Length = 529
Score = 174 bits (424), Expect = 3e-43
Identities = 88/242 (36%), Positives = 141/242 (58%), Gaps = 9/242 (3%)
Frame = -2
Query: 791 NPIRSTTYXILGELIREVQNLFPDRYYHVGGDEVDLSCWQSNPELKEYMKQHNLTAN--G 618
NP + TY + EV ++FPD Y H+GGDEVD +CW+SNPE++++M++ +
Sbjct: 291 NPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDFTCWKSNPEIQDFMRKKGFGEDFKQ 350
Query: 617 VHAMFMKEVIGRVKKTTVP-IVWQEVYDEKVPISKDTLIQVWK----YKWIDEMIKILNS 453
+ + +++ ++ V +VWQEV+D KV I DT+IQVW+ ++ E+ + +
Sbjct: 351 LESFYIQTLLDIVSSYGKGYVVWQEVFDNKVKIQPDTIIQVWREDIPVNYMKELELVTKA 410
Query: 452 GHKVVFSSSWYLDYLNF--NWNSFYGDDPRLMVYQKKKNARLENIVGGEACMWGEMADDT 279
G + + S+ WYL+ +++ +W FY +P ++ A ++GGEACMWGE D+T
Sbjct: 411 GFRALLSAPWYLNRISYGPDWKDFYVVEPLAFEGTPEQKAL---VIGGEACMWGEYVDNT 467
Query: 278 NVISRTWPRTSAVAERLWSGLDYKHPPKDPVTIHVRQRIEEHTCRMLRRGIAAEPPNGPG 99
N++ R WPR AVAERLWS + +T +R+ C +LRRG+ A+P N G
Sbjct: 468 NLVPRLWPRAGAVAERLWS-----NKLTSDLTF-AYERLSHFRCELLRRGVQAQPLN-VG 520
Query: 98 FC 93
FC
Sbjct: 521 FC 522
>BC001138-1|AAH01138.2| 409|Homo sapiens HEXA protein protein.
Length = 409
Score = 174 bits (424), Expect = 3e-43
Identities = 88/242 (36%), Positives = 141/242 (58%), Gaps = 9/242 (3%)
Frame = -2
Query: 791 NPIRSTTYXILGELIREVQNLFPDRYYHVGGDEVDLSCWQSNPELKEYMKQHNLTAN--G 618
NP + TY + EV ++FPD Y H+GGDEVD +CW+SNPE++++M++ +
Sbjct: 171 NPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDFTCWKSNPEIQDFMRKKGFGEDFKQ 230
Query: 617 VHAMFMKEVIGRVKKTTVP-IVWQEVYDEKVPISKDTLIQVWK----YKWIDEMIKILNS 453
+ + +++ ++ V +VWQEV+D KV I DT+IQVW+ ++ E+ + +
Sbjct: 231 LESFYIQTLLDIVSSYGKGYVVWQEVFDNKVKIQPDTIIQVWREDIPVNYMKELELVTKA 290
Query: 452 GHKVVFSSSWYLDYLNF--NWNSFYGDDPRLMVYQKKKNARLENIVGGEACMWGEMADDT 279
G + + S+ WYL+ +++ +W FY +P ++ A ++GGEACMWGE D+T
Sbjct: 291 GFRALLSAPWYLNRISYGPDWKDFYVVEPLAFEGTPEQKAL---VIGGEACMWGEYVDNT 347
Query: 278 NVISRTWPRTSAVAERLWSGLDYKHPPKDPVTIHVRQRIEEHTCRMLRRGIAAEPPNGPG 99
N++ R WPR AVAERLWS + +T +R+ C +LRRG+ A+P N G
Sbjct: 348 NLVPRLWPRAGAVAERLWS-----NKLTSDLTF-AYERLSHFRCELLRRGVQAQPLN-VG 400
Query: 98 FC 93
FC
Sbjct: 401 FC 402
>AK222502-1|BAD96222.1| 529|Homo sapiens hexosaminidase A
preproprotein variant protein.
Length = 529
Score = 172 bits (419), Expect = 1e-42
Identities = 87/242 (35%), Positives = 140/242 (57%), Gaps = 9/242 (3%)
Frame = -2
Query: 791 NPIRSTTYXILGELIREVQNLFPDRYYHVGGDEVDLSCWQSNPELKEYMKQHNLTAN--G 618
NP + TY + EV ++FPD Y H+GGDEVD +CW+ NPE++++M++ +
Sbjct: 291 NPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDFTCWKPNPEIQDFMRKKGFGEDFKQ 350
Query: 617 VHAMFMKEVIGRVKKTTVP-IVWQEVYDEKVPISKDTLIQVWK----YKWIDEMIKILNS 453
+ + +++ ++ V +VWQEV+D KV I DT+IQVW+ ++ E+ + +
Sbjct: 351 LESFYIQTLLDIVSSYGKGYVVWQEVFDNKVKIQPDTIIQVWREDIPVNYMKELELVTKA 410
Query: 452 GHKVVFSSSWYLDYLNF--NWNSFYGDDPRLMVYQKKKNARLENIVGGEACMWGEMADDT 279
G + + S+ WYL+ +++ +W FY +P ++ A ++GGEACMWGE D+T
Sbjct: 411 GFRALLSAPWYLNRISYGPDWKDFYVVEPLAFEGTPEQKAL---VIGGEACMWGEYVDNT 467
Query: 278 NVISRTWPRTSAVAERLWSGLDYKHPPKDPVTIHVRQRIEEHTCRMLRRGIAAEPPNGPG 99
N++ R WPR AVAERLWS + +T +R+ C +LRRG+ A+P N G
Sbjct: 468 NLVPRLWPRAGAVAERLWS-----NKLTSDLTF-AYERLSHFRCELLRRGVQAQPLN-VG 520
Query: 98 FC 93
FC
Sbjct: 521 FC 522
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 119,211,385
Number of Sequences: 237096
Number of extensions: 2722237
Number of successful extensions: 5599
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 5273
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5554
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9701808132
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -