Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P08_F_N08
(771 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase ... 59 2e-08
BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenas... 59 2e-08
BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenas... 59 2e-08
AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenas... 59 2e-08
X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase... 58 3e-08
AF197566-1|AAG43470.1| 127|Homo sapiens NADP+-specific isocitra... 48 5e-05
AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitra... 47 9e-05
CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein. 46 1e-04
CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein. 46 1e-04
BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein pr... 46 1e-04
BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenas... 46 1e-04
BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein. 46 1e-04
AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitr... 46 1e-04
AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein. 46 1e-04
CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein. 44 8e-04
DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenas... 40 0.013
>U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase
protein.
Length = 419
Score = 58.8 bits (136), Expect = 2e-08
Identities = 28/49 (57%), Positives = 34/49 (69%), Gaps = 1/49 (2%)
Frame = +3
Query: 51 CVECIDSGKMTKDLVICIHGLANTK-EGMFLHTEDFLEAIAEQLERKLG 194
CVE ++SG MTKDL CIHGL+N K FL+T DFL+ I L+R LG
Sbjct: 369 CVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALG 417
>BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 58.8 bits (136), Expect = 2e-08
Identities = 28/49 (57%), Positives = 34/49 (69%), Gaps = 1/49 (2%)
Frame = +3
Query: 51 CVECIDSGKMTKDLVICIHGLANTK-EGMFLHTEDFLEAIAEQLERKLG 194
CVE ++SG MTKDL CIHGL+N K FL+T DFL+ I L+R LG
Sbjct: 402 CVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALG 450
>BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 58.8 bits (136), Expect = 2e-08
Identities = 28/49 (57%), Positives = 34/49 (69%), Gaps = 1/49 (2%)
Frame = +3
Query: 51 CVECIDSGKMTKDLVICIHGLANTK-EGMFLHTEDFLEAIAEQLERKLG 194
CVE ++SG MTKDL CIHGL+N K FL+T DFL+ I L+R LG
Sbjct: 402 CVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALG 450
>AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial precursor variant protein.
Length = 452
Score = 58.8 bits (136), Expect = 2e-08
Identities = 28/49 (57%), Positives = 34/49 (69%), Gaps = 1/49 (2%)
Frame = +3
Query: 51 CVECIDSGKMTKDLVICIHGLANTK-EGMFLHTEDFLEAIAEQLERKLG 194
CVE ++SG MTKDL CIHGL+N K FL+T DFL+ I L+R LG
Sbjct: 402 CVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALG 450
>X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase
(NADP+) protein.
Length = 452
Score = 58.4 bits (135), Expect = 3e-08
Identities = 28/49 (57%), Positives = 34/49 (69%), Gaps = 1/49 (2%)
Frame = +3
Query: 51 CVECIDSGKMTKDLVICIHGLANTK-EGMFLHTEDFLEAIAEQLERKLG 194
CVE ++SG MTKDL CIHGL+N K FL+T DFL+ I L+R LG
Sbjct: 402 CVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTMDFLDTIKSNLDRALG 450
>AF197566-1|AAG43470.1| 127|Homo sapiens NADP+-specific isocitrate
dehydrogenase protein.
Length = 127
Score = 47.6 bits (108), Expect = 5e-05
Identities = 21/47 (44%), Positives = 32/47 (68%)
Frame = +3
Query: 51 CVECIDSGKMTKDLVICIHGLANTKEGMFLHTEDFLEAIAEQLERKL 191
C+E I++G MTKDL CI GL + + +L+T +F+E + E L+ KL
Sbjct: 41 CIETIEAGFMTKDLAACIKGLPSAQCSDYLNTFEFMEKLGENLKIKL 87
>AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 46.8 bits (106), Expect = 9e-05
Identities = 20/46 (43%), Positives = 31/46 (67%)
Frame = +3
Query: 54 VECIDSGKMTKDLVICIHGLANTKEGMFLHTEDFLEAIAEQLERKL 191
+E I++G MTKDL CI GL N + +L+T +F++ + E L+ KL
Sbjct: 364 IETIEAGFMTKDLAACIRGLPNVQRSDYLNTFEFMDKLGENLKIKL 409
>CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 46.4 bits (105), Expect = 1e-04
Identities = 20/46 (43%), Positives = 31/46 (67%)
Frame = +3
Query: 54 VECIDSGKMTKDLVICIHGLANTKEGMFLHTEDFLEAIAEQLERKL 191
+E I++G MTKDL CI GL N + +L+T +F++ + E L+ KL
Sbjct: 364 IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKL 409
>CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 46.4 bits (105), Expect = 1e-04
Identities = 20/46 (43%), Positives = 31/46 (67%)
Frame = +3
Query: 54 VECIDSGKMTKDLVICIHGLANTKEGMFLHTEDFLEAIAEQLERKL 191
+E I++G MTKDL CI GL N + +L+T +F++ + E L+ KL
Sbjct: 364 IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKL 409
>BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein
protein.
Length = 414
Score = 46.4 bits (105), Expect = 1e-04
Identities = 20/46 (43%), Positives = 31/46 (67%)
Frame = +3
Query: 54 VECIDSGKMTKDLVICIHGLANTKEGMFLHTEDFLEAIAEQLERKL 191
+E I++G MTKDL CI GL N + +L+T +F++ + E L+ KL
Sbjct: 364 IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKL 409
>BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenase 1
(NADP+), soluble protein.
Length = 414
Score = 46.4 bits (105), Expect = 1e-04
Identities = 20/46 (43%), Positives = 31/46 (67%)
Frame = +3
Query: 54 VECIDSGKMTKDLVICIHGLANTKEGMFLHTEDFLEAIAEQLERKL 191
+E I++G MTKDL CI GL N + +L+T +F++ + E L+ KL
Sbjct: 364 IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKL 409
>BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein.
Length = 414
Score = 46.4 bits (105), Expect = 1e-04
Identities = 20/46 (43%), Positives = 31/46 (67%)
Frame = +3
Query: 54 VECIDSGKMTKDLVICIHGLANTKEGMFLHTEDFLEAIAEQLERKL 191
+E I++G MTKDL CI GL N + +L+T +F++ + E L+ KL
Sbjct: 364 IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKL 409
>AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 46.4 bits (105), Expect = 1e-04
Identities = 20/46 (43%), Positives = 31/46 (67%)
Frame = +3
Query: 54 VECIDSGKMTKDLVICIHGLANTKEGMFLHTEDFLEAIAEQLERKL 191
+E I++G MTKDL CI GL N + +L+T +F++ + E L+ KL
Sbjct: 364 IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKL 409
>AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein.
Length = 414
Score = 46.4 bits (105), Expect = 1e-04
Identities = 20/46 (43%), Positives = 31/46 (67%)
Frame = +3
Query: 54 VECIDSGKMTKDLVICIHGLANTKEGMFLHTEDFLEAIAEQLERKL 191
+E I++G MTKDL CI GL N + +L+T +F++ + E L+ KL
Sbjct: 364 IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKL 409
>CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 43.6 bits (98), Expect = 8e-04
Identities = 19/46 (41%), Positives = 30/46 (65%)
Frame = +3
Query: 54 VECIDSGKMTKDLVICIHGLANTKEGMFLHTEDFLEAIAEQLERKL 191
+E I++G MTK L CI GL N + +L+T +F++ + E L+ KL
Sbjct: 364 IETIEAGFMTKGLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKL 409
>DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenase 1
protein.
Length = 371
Score = 39.5 bits (88), Expect = 0.013
Identities = 16/36 (44%), Positives = 25/36 (69%)
Frame = +3
Query: 54 VECIDSGKMTKDLVICIHGLANTKEGMFLHTEDFLE 161
+E I++G MTKDL CI GL N + +L+T +F++
Sbjct: 335 IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMD 370
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 101,268,744
Number of Sequences: 237096
Number of extensions: 2119941
Number of successful extensions: 11925
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 11787
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 11925
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9311505506
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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