Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P08_F_N01
(806 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X68836-1|CAA48726.1| 395|Homo sapiens S-adenosylmethionine synt... 244 4e-64
DQ083239-1|AAY85355.1| 395|Homo sapiens methionine adenosyltran... 244 4e-64
BC001854-1|AAH01854.1| 395|Homo sapiens methionine adenosyltran... 244 4e-64
BC001686-1|AAH01686.1| 395|Homo sapiens methionine adenosyltran... 244 4e-64
AC016753-1|AAY24339.1| 395|Homo sapiens unknown protein. 244 4e-64
X69078-1|CAA48822.1| 395|Homo sapiens methionine adenosyltransf... 233 4e-61
D49357-1|BAA08355.1| 395|Homo sapiens S-adenosylmethionine synt... 233 4e-61
BC018359-1|AAH18359.1| 395|Homo sapiens methionine adenosyltran... 233 4e-61
AL359195-2|CAI13695.1| 395|Homo sapiens methionine adenosyltran... 233 4e-61
AL359195-3|CAI13696.1| 145|Homo sapiens methionine adenosyltran... 85 4e-16
BC028352-1|AAH28352.1| 691|Homo sapiens TBC1 domain family, mem... 30 8.6
>X68836-1|CAA48726.1| 395|Homo sapiens S-adenosylmethionine
synthetase protein.
Length = 395
Score = 244 bits (596), Expect = 4e-64
Identities = 114/147 (77%), Positives = 132/147 (89%), Gaps = 1/147 (0%)
Frame = +1
Query: 367 MNGYAKTNG-HSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 543
MNG + NG H +E+G+ FLFTSESVGEGHPDK+CDQISDA+LDAHL QDPDAKVACE
Sbjct: 1 MNG--QLNGFHEAFIEEGT-FLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACE 57
Query: 544 TITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNI 723
T+ KTGM+LL GEITS+A VDYQKVVRE VKHIGYDDSSKGFDYKTC+V++AL+QQSP+I
Sbjct: 58 TVAKTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDI 117
Query: 724 AAGVHXNRNDEEVGAGDQGLMFGYATD 804
A GVH +RN+E++GAGDQGLMFGYATD
Sbjct: 118 AQGVHLDRNEEDIGAGDQGLMFGYATD 144
>DQ083239-1|AAY85355.1| 395|Homo sapiens methionine
adenosyltransferase II protein.
Length = 395
Score = 244 bits (596), Expect = 4e-64
Identities = 114/147 (77%), Positives = 132/147 (89%), Gaps = 1/147 (0%)
Frame = +1
Query: 367 MNGYAKTNG-HSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 543
MNG + NG H +E+G+ FLFTSESVGEGHPDK+CDQISDA+LDAHL QDPDAKVACE
Sbjct: 1 MNG--QLNGFHEAFIEEGT-FLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACE 57
Query: 544 TITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNI 723
T+ KTGM+LL GEITS+A VDYQKVVRE VKHIGYDDSSKGFDYKTC+V++AL+QQSP+I
Sbjct: 58 TVAKTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDI 117
Query: 724 AAGVHXNRNDEEVGAGDQGLMFGYATD 804
A GVH +RN+E++GAGDQGLMFGYATD
Sbjct: 118 AQGVHLDRNEEDIGAGDQGLMFGYATD 144
>BC001854-1|AAH01854.1| 395|Homo sapiens methionine
adenosyltransferase II, alpha protein.
Length = 395
Score = 244 bits (596), Expect = 4e-64
Identities = 114/147 (77%), Positives = 132/147 (89%), Gaps = 1/147 (0%)
Frame = +1
Query: 367 MNGYAKTNG-HSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 543
MNG + NG H +E+G+ FLFTSESVGEGHPDK+CDQISDA+LDAHL QDPDAKVACE
Sbjct: 1 MNG--QLNGFHEAFIEEGT-FLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACE 57
Query: 544 TITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNI 723
T+ KTGM+LL GEITS+A VDYQKVVRE VKHIGYDDSSKGFDYKTC+V++AL+QQSP+I
Sbjct: 58 TVAKTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDI 117
Query: 724 AAGVHXNRNDEEVGAGDQGLMFGYATD 804
A GVH +RN+E++GAGDQGLMFGYATD
Sbjct: 118 AQGVHLDRNEEDIGAGDQGLMFGYATD 144
>BC001686-1|AAH01686.1| 395|Homo sapiens methionine
adenosyltransferase II, alpha protein.
Length = 395
Score = 244 bits (596), Expect = 4e-64
Identities = 114/147 (77%), Positives = 132/147 (89%), Gaps = 1/147 (0%)
Frame = +1
Query: 367 MNGYAKTNG-HSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 543
MNG + NG H +E+G+ FLFTSESVGEGHPDK+CDQISDA+LDAHL QDPDAKVACE
Sbjct: 1 MNG--QLNGFHEAFIEEGT-FLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACE 57
Query: 544 TITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNI 723
T+ KTGM+LL GEITS+A VDYQKVVRE VKHIGYDDSSKGFDYKTC+V++AL+QQSP+I
Sbjct: 58 TVAKTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDI 117
Query: 724 AAGVHXNRNDEEVGAGDQGLMFGYATD 804
A GVH +RN+E++GAGDQGLMFGYATD
Sbjct: 118 AQGVHLDRNEEDIGAGDQGLMFGYATD 144
>AC016753-1|AAY24339.1| 395|Homo sapiens unknown protein.
Length = 395
Score = 244 bits (596), Expect = 4e-64
Identities = 114/147 (77%), Positives = 132/147 (89%), Gaps = 1/147 (0%)
Frame = +1
Query: 367 MNGYAKTNG-HSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 543
MNG + NG H +E+G+ FLFTSESVGEGHPDK+CDQISDA+LDAHL QDPDAKVACE
Sbjct: 1 MNG--QLNGFHEAFIEEGT-FLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACE 57
Query: 544 TITKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNI 723
T+ KTGM+LL GEITS+A VDYQKVVRE VKHIGYDDSSKGFDYKTC+V++AL+QQSP+I
Sbjct: 58 TVAKTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDI 117
Query: 724 AAGVHXNRNDEEVGAGDQGLMFGYATD 804
A GVH +RN+E++GAGDQGLMFGYATD
Sbjct: 118 AQGVHLDRNEEDIGAGDQGLMFGYATD 144
>X69078-1|CAA48822.1| 395|Homo sapiens methionine
adenosyltransferase protein.
Length = 395
Score = 233 bits (571), Expect = 4e-61
Identities = 104/135 (77%), Positives = 125/135 (92%)
Frame = +1
Query: 400 YDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETITKTGMVLLCG 579
+ + +G VF+FTSESVGEGHPDK+CDQISDA+LDAHL QDP+AKVACET+ KTGMVLLCG
Sbjct: 11 HSLSEG-VFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCG 69
Query: 580 EITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGVHXNRNDEE 759
EITS A VDYQ+VVR+T+KHIGYDDS+KGFD+KTC+V++AL+QQSP+IA VH +RN+E+
Sbjct: 70 EITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEED 129
Query: 760 VGAGDQGLMFGYATD 804
VGAGDQGLMFGYATD
Sbjct: 130 VGAGDQGLMFGYATD 144
>D49357-1|BAA08355.1| 395|Homo sapiens S-adenosylmethionine
synthetase protein.
Length = 395
Score = 233 bits (571), Expect = 4e-61
Identities = 104/135 (77%), Positives = 125/135 (92%)
Frame = +1
Query: 400 YDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETITKTGMVLLCG 579
+ + +G VF+FTSESVGEGHPDK+CDQISDA+LDAHL QDP+AKVACET+ KTGMVLLCG
Sbjct: 11 HSLSEG-VFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCG 69
Query: 580 EITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGVHXNRNDEE 759
EITS A VDYQ+VVR+T+KHIGYDDS+KGFD+KTC+V++AL+QQSP+IA VH +RN+E+
Sbjct: 70 EITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEED 129
Query: 760 VGAGDQGLMFGYATD 804
VGAGDQGLMFGYATD
Sbjct: 130 VGAGDQGLMFGYATD 144
>BC018359-1|AAH18359.1| 395|Homo sapiens methionine
adenosyltransferase I, alpha protein.
Length = 395
Score = 233 bits (571), Expect = 4e-61
Identities = 104/135 (77%), Positives = 125/135 (92%)
Frame = +1
Query: 400 YDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETITKTGMVLLCG 579
+ + +G VF+FTSESVGEGHPDK+CDQISDA+LDAHL QDP+AKVACET+ KTGMVLLCG
Sbjct: 11 HSLSEG-VFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCG 69
Query: 580 EITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGVHXNRNDEE 759
EITS A VDYQ+VVR+T+KHIGYDDS+KGFD+KTC+V++AL+QQSP+IA VH +RN+E+
Sbjct: 70 EITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEED 129
Query: 760 VGAGDQGLMFGYATD 804
VGAGDQGLMFGYATD
Sbjct: 130 VGAGDQGLMFGYATD 144
>AL359195-2|CAI13695.1| 395|Homo sapiens methionine
adenosyltransferase I, alpha protein.
Length = 395
Score = 233 bits (571), Expect = 4e-61
Identities = 104/135 (77%), Positives = 125/135 (92%)
Frame = +1
Query: 400 YDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETITKTGMVLLCG 579
+ + +G VF+FTSESVGEGHPDK+CDQISDA+LDAHL QDP+AKVACET+ KTGMVLLCG
Sbjct: 11 HSLSEG-VFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCG 69
Query: 580 EITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGVHXNRNDEE 759
EITS A VDYQ+VVR+T+KHIGYDDS+KGFD+KTC+V++AL+QQSP+IA VH +RN+E+
Sbjct: 70 EITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEED 129
Query: 760 VGAGDQGLMFGYATD 804
VGAGDQGLMFGYATD
Sbjct: 130 VGAGDQGLMFGYATD 144
>AL359195-3|CAI13696.1| 145|Homo sapiens methionine
adenosyltransferase I, alpha protein.
Length = 145
Score = 84.6 bits (200), Expect = 4e-16
Identities = 38/59 (64%), Positives = 50/59 (84%), Gaps = 3/59 (5%)
Frame = +1
Query: 637 HIGYDDSSK---GFDYKTCSVMLALDQQSPNIAAGVHXNRNDEEVGAGDQGLMFGYATD 804
H+ D ++K GFD+KTC+V++AL+QQSP+IA VH +RN+E+VGAGDQGLMFGYATD
Sbjct: 23 HLKQDPNAKVACGFDFKTCNVLVALEQQSPDIAQCVHLDRNEEDVGAGDQGLMFGYATD 81
Score = 75.8 bits (178), Expect = 2e-13
Identities = 42/81 (51%), Positives = 49/81 (60%)
Frame = +1
Query: 439 ESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETITKTGMVLLCGEITSKANVDYQKV 618
ESVGEGHPDK+CDQISDA+LDAHL QDP+AKVAC KT VL+ E S +
Sbjct: 1 ESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACGFDFKTCNVLVALEQQSPDIAQCVHL 60
Query: 619 VRETVKHIGYDDSSKGFDYKT 681
R + +G D F Y T
Sbjct: 61 DRNE-EDVGAGDQGLMFGYAT 80
>BC028352-1|AAH28352.1| 691|Homo sapiens TBC1 domain family, member
15 protein.
Length = 691
Score = 30.3 bits (65), Expect = 8.6
Identities = 20/66 (30%), Positives = 31/66 (46%)
Frame = +1
Query: 328 WANSKFRMPETSKMNGYAKTNGHSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAH 507
W K + P T+ M G++K + +D GS S + P +M D +SDAI
Sbjct: 235 WKKIK-KDPYTATMIGFSKVTNYIFDSLRGS-----DPSTHQRPPSEMADFLSDAIPGLK 288
Query: 508 LNQDPD 525
+NQ +
Sbjct: 289 INQQEE 294
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 114,654,005
Number of Sequences: 237096
Number of extensions: 2486325
Number of successful extensions: 3638
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 3502
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3638
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9980595722
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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