Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P08_F_H22
(886 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family... 160 7e-39
AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2 pro... 160 7e-39
AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens ... 160 7e-39
AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens ... 160 7e-39
BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein. 101 5e-21
AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein. 101 5e-21
D12621-1|BAA02145.1| 389|Homo sapiens cytochrome P-450LTBV prot... 97 6e-20
D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV prot... 97 6e-20
AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family... 97 6e-20
AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4 omega-hy... 97 6e-20
AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4 omega-hy... 97 6e-20
AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein. 97 7e-20
AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein. 97 1e-19
U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein. 96 2e-19
D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4 omega-hydr... 96 2e-19
BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family... 96 2e-19
BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family... 96 2e-19
AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfam... 96 2e-19
AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein. 96 2e-19
AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4 omega-hy... 96 2e-19
BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family... 95 2e-19
BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family... 95 4e-19
AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein. 95 4e-19
AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform... 95 4e-19
AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein. 95 4e-19
AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein. 95 4e-19
AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein. 93 2e-18
BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family... 88 5e-17
BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family... 88 5e-17
BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family... 88 5e-17
AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens ... 86 2e-16
BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family... 85 2e-16
AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein. 85 2e-16
AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein. 85 2e-16
AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family... 85 2e-16
AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens ... 85 2e-16
AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens ... 85 2e-16
AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens ... 85 3e-16
AK097373-1|BAC05026.1| 340|Homo sapiens protein ( Homo sapiens ... 83 2e-15
AY696295-1|AAU10524.1| 292|Homo sapiens cytochrome P450 protein. 82 3e-15
AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein. 81 4e-15
AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein. 81 4e-15
AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family... 81 4e-15
AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family... 81 4e-15
S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxyl... 81 7e-15
S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxyl... 81 7e-15
L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein. 81 7e-15
D26481-1|BAA05491.1| 519|Homo sapiens fatty acids omega-hydroxy... 81 7e-15
BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein. 81 7e-15
AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family... 81 7e-15
AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family... 81 7e-15
AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family... 81 7e-15
AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfam... 81 7e-15
D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxyl... 80 9e-15
AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22 pr... 80 1e-14
BC142607-1|AAI42608.1| 455|Homo sapiens CYP4A22 protein protein. 79 3e-14
AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K p... 79 3e-14
J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung cyto... 78 5e-14
X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for ... 77 6e-14
DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family... 77 6e-14
AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein. 77 6e-14
AY064484-1|AAL57719.1| 295|Homo sapiens truncated cytochrome P4... 77 6e-14
AL593856-6|CAI16981.1| 511|Homo sapiens cytochrome P450, family... 77 6e-14
AL356793-3|CAI22559.1| 511|Homo sapiens cytochrome P450, family... 77 6e-14
AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein. 77 6e-14
AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein. 77 9e-14
AF221943-1|AAF86378.1| 175|Homo sapiens leukotriene B4 omega hy... 75 3e-13
BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family... 75 3e-13
AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P4... 75 3e-13
AL593856-7|CAI16982.1| 512|Homo sapiens cytochrome P450, family... 75 3e-13
AL356793-4|CAI22557.1| 512|Homo sapiens cytochrome P450, family... 75 3e-13
AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid omega-hydrox... 73 1e-12
BC022851-1|AAH22851.1| 215|Homo sapiens CYP4A11 protein protein. 72 3e-12
AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, famil... 72 3e-12
AL135960-9|CAI19737.1| 519|Homo sapiens cytochrome P450, family... 72 3e-12
BC142690-1|AAI42691.1| 357|Homo sapiens CYP4A22 protein protein. 68 4e-11
AL135960-10|CAI19736.1| 421|Homo sapiens cytochrome P450, famil... 67 7e-11
AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P4... 63 1e-09
AL593856-5|CAI16983.1| 497|Homo sapiens cytochrome P450, family... 63 1e-09
AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family... 63 1e-09
X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for ... 40 0.016
M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA... 40 0.016
M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrom... 40 0.016
DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family ... 40 0.016
DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family... 40 0.016
BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfam... 40 0.016
BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family... 40 0.016
AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein. 40 0.016
AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450 polypep... 40 0.016
AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4 p... 40 0.016
AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4 pro... 40 0.016
J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipin... 37 0.085
AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein. 37 0.085
D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa pro... 37 0.11
BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family... 37 0.11
AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant... 37 0.11
AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450 polypep... 37 0.11
J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein. 36 0.20
AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43... 36 0.20
AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43... 36 0.20
AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfami... 36 0.20
AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43... 36 0.20
AF280111-1|AAG33012.1| 250|Homo sapiens cytochrome P450 subfami... 36 0.20
AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfami... 36 0.20
AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfami... 36 0.20
AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfami... 36 0.20
AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein. 36 0.20
AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein. 36 0.20
EF122242-1|ABO41977.1| 321|Homo sapiens cytochrome P450 2F1 var... 36 0.26
EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1 var... 36 0.26
BC109056-1|AAI09057.1| 320|Homo sapiens CYP2F1 protein protein. 36 0.26
AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1 pro... 36 0.26
M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver glu... 35 0.45
D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein. 35 0.45
U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450 monooxyge... 32 3.2
BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family... 32 3.2
AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family... 32 3.2
AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein. 32 3.2
AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2 pro... 32 3.2
J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3 prot... 31 4.2
DQ680079-1|ABG25922.1| 347|Homo sapiens truncated cytochrome P4... 31 4.2
BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family... 31 4.2
AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein. 31 4.2
AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family... 31 5.6
BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family... 31 7.3
AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein. 31 7.3
AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens ... 31 7.3
AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1 pro... 31 7.3
AF144566-1|AAD30164.1| 339|Homo sapiens cytochrome P450 epoxyge... 30 9.7
>BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family 4,
subfamily V, polypeptide 2 protein.
Length = 525
Score = 160 bits (388), Expect = 7e-39
Identities = 75/194 (38%), Positives = 116/194 (59%), Gaps = 2/194 (1%)
Frame = +2
Query: 308 DIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWL 487
+ F+ I++ + +Y H ++K+W+GP +V LY+ +VEVIL+S IDK+ Y+F +PWL
Sbjct: 72 EFFQQIIEYTEEYRHMPLLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSMYKFLEPWL 131
Query: 488 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIELFNANSRAVVDKLKKEASN--FDCHDY 661
G GLL STG KWRS RK++ PTFH +L+ F+++ N + +V KL+K + F+C Y
Sbjct: 132 GLGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQEAFNCFFY 191
Query: 662 MSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYA 841
++ C ++I+ ETAMG + Q EY AV +M +++ R WL DL +
Sbjct: 192 ITLCALDIICETAMGKNIGAQSNDDSEYVRAVYRMSEMIFRRIKMPWLWLDLWYLMFKEG 251
Query: 842 KNQTKLLDIIHGLT 883
K L I+H T
Sbjct: 252 WEHKKSLKILHTFT 265
>AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2
protein.
Length = 525
Score = 160 bits (388), Expect = 7e-39
Identities = 75/194 (38%), Positives = 116/194 (59%), Gaps = 2/194 (1%)
Frame = +2
Query: 308 DIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWL 487
+ F+ I++ + +Y H ++K+W+GP +V LY+ +VEVIL+S IDK+ Y+F +PWL
Sbjct: 72 EFFQQIIEYTEEYRHMPLLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSMYKFLEPWL 131
Query: 488 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIELFNANSRAVVDKLKKEASN--FDCHDY 661
G GLL STG KWRS RK++ PTFH +L+ F+++ N + +V KL+K + F+C Y
Sbjct: 132 GLGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQEAFNCFFY 191
Query: 662 MSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYA 841
++ C ++I+ ETAMG + Q EY AV +M +++ R WL DL +
Sbjct: 192 ITLCALDIICETAMGKNIGAQSNDDSEYVRAVYRMSEMIFRRIKMPWLWLDLWYLMFKEG 251
Query: 842 KNQTKLLDIIHGLT 883
K L I+H T
Sbjct: 252 WEHKKSLKILHTFT 265
>AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens
cDNA FLJ44509 fis, clone UTERU3001585, weakly similar
to Cytochrome P450 4c3 (EC 1.14.-.-). ).
Length = 503
Score = 160 bits (388), Expect = 7e-39
Identities = 75/194 (38%), Positives = 116/194 (59%), Gaps = 2/194 (1%)
Frame = +2
Query: 308 DIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWL 487
+ F+ I++ + +Y H ++K+W+GP +V LY+ +VEVIL+S IDK+ Y+F +PWL
Sbjct: 50 EFFQQIIEYTEEYRHMPLLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSMYKFLEPWL 109
Query: 488 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIELFNANSRAVVDKLKKEASN--FDCHDY 661
G GLL STG KWRS RK++ PTFH +L+ F+++ N + +V KL+K + F+C Y
Sbjct: 110 GLGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQEAFNCFFY 169
Query: 662 MSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYA 841
++ C ++I+ ETAMG + Q EY AV +M +++ R WL DL +
Sbjct: 170 ITLCALDIICETAMGKNIGAQSNDDSEYVRAVYRMSEMIFRRIKMPWLWLDLWYLMFKEG 229
Query: 842 KNQTKLLDIIHGLT 883
K L I+H T
Sbjct: 230 WEHKKSLKILHTFT 243
>AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens
cDNA FLJ16007 fis, clone KIDNE2006580, weakly similar
to CYTOCHROME P450 4C1 (EC 1.14.14.1). ).
Length = 525
Score = 160 bits (388), Expect = 7e-39
Identities = 75/194 (38%), Positives = 116/194 (59%), Gaps = 2/194 (1%)
Frame = +2
Query: 308 DIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWL 487
+ F+ I++ + +Y H ++K+W+GP +V LY+ +VEVIL+S IDK+ Y+F +PWL
Sbjct: 72 EFFQQIIEYTEEYRHMPLLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSMYKFLEPWL 131
Query: 488 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIELFNANSRAVVDKLKKEASN--FDCHDY 661
G GLL STG KWRS RK++ PTFH +L+ F+++ N + +V KL+K + F+C Y
Sbjct: 132 GLGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQEAFNCFFY 191
Query: 662 MSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYA 841
++ C ++I+ ETAMG + Q EY AV +M +++ R WL DL +
Sbjct: 192 ITLCALDIICETAMGKNIGAQSNDDSEYVRAVYRMSEMIFRRIKMPWLWLDLWYLMFKEG 251
Query: 842 KNQTKLLDIIHGLT 883
K L I+H T
Sbjct: 252 WEHKKSLKILHTFT 265
>BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein.
Length = 524
Score = 101 bits (241), Expect = 5e-21
Identities = 53/180 (29%), Positives = 95/180 (52%), Gaps = 7/180 (3%)
Frame = +2
Query: 365 KIWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHR 535
K+W+GP L+ L P + I S+ + + Y F KPWLG+GLL+S G KW HR
Sbjct: 89 KLWLGPTFPLLILCHPDIIRPITSASAAVAPKDMIFYGFLKPWLGDGLLLSGGDKWSRHR 148
Query: 536 KLIAPTFHLNVLKSFIELFNANSRAVVDKLKKEAS----NFDCHDYMSECTVEILLETAM 703
+++ P FH N+LK ++++FN + + DK ++ AS D +++S T++ L +
Sbjct: 149 RMLTPAFHFNILKPYMKIFNKSVNIMHDKWQRLASEGSARLDMFEHISLMTLDSLQKCVF 208
Query: 704 GVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 883
+ Q++ EY A++++ + R+ +I L D L+ T + + ++H T
Sbjct: 209 SFESNCQEKPS-EYIAAILELSAFVEKRNQQILLHTDFLYYLTPDGQRFRRACHLVHDFT 267
>AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein.
Length = 524
Score = 101 bits (241), Expect = 5e-21
Identities = 53/180 (29%), Positives = 95/180 (52%), Gaps = 7/180 (3%)
Frame = +2
Query: 365 KIWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHR 535
K+W+GP L+ L P + I S+ + + Y F KPWLG+GLL+S G KW HR
Sbjct: 89 KLWLGPTFPLLILCHPDIIRPITSASAAVAPKDMIFYGFLKPWLGDGLLLSGGDKWSRHR 148
Query: 536 KLIAPTFHLNVLKSFIELFNANSRAVVDKLKKEAS----NFDCHDYMSECTVEILLETAM 703
+++ P FH N+LK ++++FN + + DK ++ AS D +++S T++ L +
Sbjct: 149 RMLTPAFHFNILKPYMKIFNKSVNIMHDKWQRLASEGSARLDMFEHISLMTLDSLQKCVF 208
Query: 704 GVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 883
+ Q++ EY A++++ + R+ +I L D L+ T + + ++H T
Sbjct: 209 SFESNCQEKPS-EYIAAILELSAFVEKRNQQILLHTDFLYYLTPDGQRFRRACHLVHDFT 267
>D12621-1|BAA02145.1| 389|Homo sapiens cytochrome P-450LTBV
protein.
Length = 389
Score = 97.5 bits (232), Expect = 6e-20
Identities = 52/178 (29%), Positives = 95/178 (53%), Gaps = 7/178 (3%)
Frame = +2
Query: 371 WIGP-RLLVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHRKL 541
W+GP +V ++ P ++ +L + I ++ Y F KPWLG+GLL+S G+KW HR++
Sbjct: 91 WVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVFYSFLKPWLGDGLLLSAGEKWSRHRRM 150
Query: 542 IAPTFHLNVLKSFIELFNANSRAVVDK---LKKEAS-NFDCHDYMSECTVEILLETAMGV 709
+ P FH N+LK ++++FN + + K L E S D +++S T++ L +
Sbjct: 151 LTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLMTLDSLQKCVFSF 210
Query: 710 SKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 883
Q++ EY A++++ ++ RH +I L D L+ T + + ++H T
Sbjct: 211 DSHCQEKPS-EYIAAILELSALVTKRHQQILLYIDFLYYLTPDGQRFRRACRLVHDFT 267
>D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV
protein.
Length = 520
Score = 97.5 bits (232), Expect = 6e-20
Identities = 52/178 (29%), Positives = 95/178 (53%), Gaps = 7/178 (3%)
Frame = +2
Query: 371 WIGP-RLLVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHRKL 541
W+GP +V ++ P ++ +L + I ++ Y F KPWLG+GLL+S G+KW HR++
Sbjct: 91 WVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVFYSFLKPWLGDGLLLSAGEKWSRHRRM 150
Query: 542 IAPTFHLNVLKSFIELFNANSRAVVDK---LKKEAS-NFDCHDYMSECTVEILLETAMGV 709
+ P FH N+LK ++++FN + + K L E S D +++S T++ L +
Sbjct: 151 LTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLMTLDSLQKCVFSF 210
Query: 710 SKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 883
Q++ EY A++++ ++ RH +I L D L+ T + + ++H T
Sbjct: 211 DSHCQEKPS-EYIAAILELSALVTKRHQQILLYIDFLYYLTPDGQRFRRACRLVHDFT 267
>AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 3 protein.
Length = 520
Score = 97.5 bits (232), Expect = 6e-20
Identities = 52/178 (29%), Positives = 95/178 (53%), Gaps = 7/178 (3%)
Frame = +2
Query: 371 WIGP-RLLVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHRKL 541
W+GP +V ++ P ++ +L + I ++ Y F KPWLG+GLL+S G+KW HR++
Sbjct: 91 WVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVFYSFLKPWLGDGLLLSAGEKWSRHRRM 150
Query: 542 IAPTFHLNVLKSFIELFNANSRAVVDK---LKKEAS-NFDCHDYMSECTVEILLETAMGV 709
+ P FH N+LK ++++FN + + K L E S D +++S T++ L +
Sbjct: 151 LTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLMTLDSLQKCVFSF 210
Query: 710 SKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 883
Q++ EY A++++ ++ RH +I L D L+ T + + ++H T
Sbjct: 211 DSHCQEKPS-EYIAAILELSALVTKRHQQILLYIDFLYYLTPDGQRFRRACRLVHDFT 267
>AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 97.5 bits (232), Expect = 6e-20
Identities = 52/178 (29%), Positives = 95/178 (53%), Gaps = 7/178 (3%)
Frame = +2
Query: 371 WIGP-RLLVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHRKL 541
W+GP +V ++ P ++ +L + I ++ Y F KPWLG+GLL+S G+KW HR++
Sbjct: 91 WVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVFYSFLKPWLGDGLLLSAGEKWSRHRRM 150
Query: 542 IAPTFHLNVLKSFIELFNANSRAVVDK---LKKEAS-NFDCHDYMSECTVEILLETAMGV 709
+ P FH N+LK ++++FN + + K L E S D +++S T++ L +
Sbjct: 151 LTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLMTLDSLQKCVFSF 210
Query: 710 SKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 883
Q++ EY A++++ ++ RH +I L D L+ T + + ++H T
Sbjct: 211 DSHCQEKPS-EYIAAILELSALVTKRHQQILLYIDFLYYLTPDGQRFRRACRLVHDFT 267
>AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 97.5 bits (232), Expect = 6e-20
Identities = 52/178 (29%), Positives = 95/178 (53%), Gaps = 7/178 (3%)
Frame = +2
Query: 371 WIGP-RLLVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHRKL 541
W+GP +V ++ P ++ +L + I ++ Y F KPWLG+GLL+S G+KW HR++
Sbjct: 91 WVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVFYSFLKPWLGDGLLLSAGEKWSRHRRM 150
Query: 542 IAPTFHLNVLKSFIELFNANSRAVVDK---LKKEAS-NFDCHDYMSECTVEILLETAMGV 709
+ P FH N+LK ++++FN + + K L E S D +++S T++ L +
Sbjct: 151 LTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLMTLDSLQKCVFSF 210
Query: 710 SKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 883
Q++ EY A++++ ++ RH +I L D L+ T + + ++H T
Sbjct: 211 DSHCQEKPS-EYIAAILELSALVTKRHQQILLYIDFLYYLTPDGQRFRRACRLVHDFT 267
>AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein.
Length = 520
Score = 97.1 bits (231), Expect = 7e-20
Identities = 51/180 (28%), Positives = 95/180 (52%), Gaps = 7/180 (3%)
Frame = +2
Query: 365 KIWIGPRLLVFLY-DPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHR 535
K+W+GP V + P + ++++ I ++ Y F KPWLG+GLL+S G+KW HR
Sbjct: 89 KVWMGPIFPVIRFCHPNIIRSVINASAAIVPKDKVFYSFLKPWLGDGLLLSAGEKWSRHR 148
Query: 536 KLIAPTFHLNVLKSFIELFNANSRAVVDKLKKEAS----NFDCHDYMSECTVEILLETAM 703
+++ P FH N+LK ++++FN + + K + AS D +++S T++ L +
Sbjct: 149 RMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASKGYARLDMFEHISLMTLDSLQKCVF 208
Query: 704 GVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 883
Q++ EY A++++ ++ RH +I L D L+ T + + ++H T
Sbjct: 209 SFDSHCQEKPS-EYIAAILELSALVTKRHQQILLYIDFLYYLTPDGQRFRRACRLVHDFT 267
>AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein.
Length = 458
Score = 96.7 bits (230), Expect = 1e-19
Identities = 56/196 (28%), Positives = 97/196 (49%), Gaps = 7/196 (3%)
Frame = +2
Query: 317 RNIVQKSADYDHESVVKIWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEEY--RFFKPWL 487
+N Q SA Y IW+GP + + L P + I ++ I + RF KPWL
Sbjct: 9 KNSTQMSATYSQGFT--IWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWL 66
Query: 488 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIELFNANSRAVVDK---LKKEASN-FDCH 655
G G+L+S G KW HR+++ P FH N+LKS+I +FN ++ ++DK L E S+ D
Sbjct: 67 GEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSCLDMF 126
Query: 656 DYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTD 835
+++S T++ L + Q++ EY ++++ ++ R I D L+ +
Sbjct: 127 EHISLMTLDSLQKCIFSFDSHCQERPS-EYIATILELSALVEKRSQHILQHMDFLYYLSH 185
Query: 836 YAKNQTKLLDIIHGLT 883
+ + ++H T
Sbjct: 186 DGRRFHRACRLVHDFT 201
>U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein.
Length = 520
Score = 95.9 bits (228), Expect = 2e-19
Identities = 51/180 (28%), Positives = 95/180 (52%), Gaps = 7/180 (3%)
Frame = +2
Query: 365 KIWIGP-RLLVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHR 535
K+W+GP L+ L P + ++++ I ++ Y F +PWLG+GLL+S G KW HR
Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148
Query: 536 KLIAPTFHLNVLKSFIELFNANSRAVVDKLKKEASN----FDCHDYMSECTVEILLETAM 703
+++ P FH N+LK ++++FN + + K + AS D +++S T++ L +
Sbjct: 149 RMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVF 208
Query: 704 GVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 883
Q++ EY A++++ ++ RH +I L D L+ T + + ++H T
Sbjct: 209 SFDSHCQEKPS-EYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRFRRACRLVHDFT 267
>D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 95.9 bits (228), Expect = 2e-19
Identities = 51/180 (28%), Positives = 95/180 (52%), Gaps = 7/180 (3%)
Frame = +2
Query: 365 KIWIGP-RLLVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHR 535
K+W+GP L+ L P + ++++ I ++ Y F +PWLG+GLL+S G KW HR
Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148
Query: 536 KLIAPTFHLNVLKSFIELFNANSRAVVDKLKKEASN----FDCHDYMSECTVEILLETAM 703
+++ P FH N+LK ++++FN + + K + AS D +++S T++ L +
Sbjct: 149 RMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVF 208
Query: 704 GVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 883
Q++ EY A++++ ++ RH +I L D L+ T + + ++H T
Sbjct: 209 SFDSHCQEKPS-EYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRFRRACRLVHDFT 267
>BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 95.9 bits (228), Expect = 2e-19
Identities = 51/180 (28%), Positives = 95/180 (52%), Gaps = 7/180 (3%)
Frame = +2
Query: 365 KIWIGP-RLLVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHR 535
K+W+GP L+ L P + ++++ I ++ Y F +PWLG+GLL+S G KW HR
Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148
Query: 536 KLIAPTFHLNVLKSFIELFNANSRAVVDKLKKEASN----FDCHDYMSECTVEILLETAM 703
+++ P FH N+LK ++++FN + + K + AS D +++S T++ L +
Sbjct: 149 RMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVF 208
Query: 704 GVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 883
Q++ EY A++++ ++ RH +I L D L+ T + + ++H T
Sbjct: 209 SFDSHCQEKPS-EYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRFRRACRLVHDFT 267
>BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 95.9 bits (228), Expect = 2e-19
Identities = 51/180 (28%), Positives = 95/180 (52%), Gaps = 7/180 (3%)
Frame = +2
Query: 365 KIWIGP-RLLVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHR 535
K+W+GP L+ L P + ++++ I ++ Y F +PWLG+GLL+S G KW HR
Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148
Query: 536 KLIAPTFHLNVLKSFIELFNANSRAVVDKLKKEASN----FDCHDYMSECTVEILLETAM 703
+++ P FH N+LK ++++FN + + K + AS D +++S T++ L +
Sbjct: 149 RMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVF 208
Query: 704 GVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 883
Q++ EY A++++ ++ RH +I L D L+ T + + ++H T
Sbjct: 209 SFDSHCQEKPS-EYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRFRRACRLVHDFT 267
>AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfamily
IVF, polypeptide 2 protein.
Length = 520
Score = 95.9 bits (228), Expect = 2e-19
Identities = 51/180 (28%), Positives = 95/180 (52%), Gaps = 7/180 (3%)
Frame = +2
Query: 365 KIWIGP-RLLVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHR 535
K+W+GP L+ L P + ++++ I ++ Y F +PWLG+GLL+S G KW HR
Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148
Query: 536 KLIAPTFHLNVLKSFIELFNANSRAVVDKLKKEASN----FDCHDYMSECTVEILLETAM 703
+++ P FH N+LK ++++FN + + K + AS D +++S T++ L +
Sbjct: 149 RMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVF 208
Query: 704 GVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 883
Q++ EY A++++ ++ RH +I L D L+ T + + ++H T
Sbjct: 209 SFDSHCQEKPS-EYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRFRRACRLVHDFT 267
>AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein.
Length = 520
Score = 95.9 bits (228), Expect = 2e-19
Identities = 51/180 (28%), Positives = 95/180 (52%), Gaps = 7/180 (3%)
Frame = +2
Query: 365 KIWIGP-RLLVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHR 535
K+W+GP L+ L P + ++++ I ++ Y F +PWLG+GLL+S G KW HR
Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148
Query: 536 KLIAPTFHLNVLKSFIELFNANSRAVVDKLKKEASN----FDCHDYMSECTVEILLETAM 703
+++ P FH N+LK ++++FN + + K + AS D +++S T++ L +
Sbjct: 149 RMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVF 208
Query: 704 GVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 883
Q++ EY A++++ ++ RH +I L D L+ T + + ++H T
Sbjct: 209 SFDSHCQEKPS-EYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRFRRACRLVHDFT 267
>AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 95.9 bits (228), Expect = 2e-19
Identities = 51/180 (28%), Positives = 95/180 (52%), Gaps = 7/180 (3%)
Frame = +2
Query: 365 KIWIGP-RLLVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHR 535
K+W+GP L+ L P + ++++ I ++ Y F +PWLG+GLL+S G KW HR
Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148
Query: 536 KLIAPTFHLNVLKSFIELFNANSRAVVDKLKKEASN----FDCHDYMSECTVEILLETAM 703
+++ P FH N+LK ++++FN + + K + AS D +++S T++ L +
Sbjct: 149 RMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVF 208
Query: 704 GVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 883
Q++ EY A++++ ++ RH +I L D L+ T + + ++H T
Sbjct: 209 SFDSHCQEKPS-EYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRFRRACRLVHDFT 267
>BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 95.5 bits (227), Expect = 2e-19
Identities = 51/180 (28%), Positives = 95/180 (52%), Gaps = 7/180 (3%)
Frame = +2
Query: 365 KIWIGP-RLLVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHR 535
K+W+GP L+ L P + ++++ I ++ Y F +PWLG+GLL+S G KW HR
Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148
Query: 536 KLIAPTFHLNVLKSFIELFNANSRAVVDKLKKEASN----FDCHDYMSECTVEILLETAM 703
+++ P FH N+LK ++++FN + + K + AS D +++S T++ L +
Sbjct: 149 RMLTPAFHFNILKPYMKIFNDSVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVF 208
Query: 704 GVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 883
Q++ EY A++++ ++ RH +I L D L+ T + + ++H T
Sbjct: 209 SFDSHCQEKPS-EYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRFRRACRLVHDFT 267
>BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 12 protein.
Length = 524
Score = 94.7 bits (225), Expect = 4e-19
Identities = 55/196 (28%), Positives = 97/196 (49%), Gaps = 7/196 (3%)
Frame = +2
Query: 317 RNIVQKSADYDHESVVKIWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEEY--RFFKPWL 487
++ Q SA Y V W+GP + + L P + I ++ I + RF KPWL
Sbjct: 75 KDSTQMSATYSQGFTV--WLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWL 132
Query: 488 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIELFNANSRAVVDK---LKKEASN-FDCH 655
G G+L+S G KW HR+++ P FH N+LKS+I +FN ++ ++DK L E S+ D
Sbjct: 133 GEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSCLDMF 192
Query: 656 DYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTD 835
+++S T++ L + Q++ EY ++++ ++ R I D L+ +
Sbjct: 193 EHISLMTLDSLQKCIFSFDSHCQERPS-EYIATILELSALVEKRSQHILQHMDFLYYLSH 251
Query: 836 YAKNQTKLLDIIHGLT 883
+ + ++H T
Sbjct: 252 DGRRFHRACRLVHDFT 267
>AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein.
Length = 524
Score = 94.7 bits (225), Expect = 4e-19
Identities = 55/196 (28%), Positives = 97/196 (49%), Gaps = 7/196 (3%)
Frame = +2
Query: 317 RNIVQKSADYDHESVVKIWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEEY--RFFKPWL 487
++ Q SA Y V W+GP + + L P + I ++ I + RF KPWL
Sbjct: 75 KDSTQMSATYSQGFTV--WLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWL 132
Query: 488 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIELFNANSRAVVDK---LKKE-ASNFDCH 655
G G+L+S G KW HR+++ P FH N+LKS+I +FN ++ ++DK L E +S D
Sbjct: 133 GEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMF 192
Query: 656 DYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTD 835
+++S T++ L + Q++ EY ++++ ++ R I D L+ +
Sbjct: 193 EHISLMTLDSLQKCIFSFDSHCQERPS-EYIATILELSALVEKRSQHILQHMDFLYYLSH 251
Query: 836 YAKNQTKLLDIIHGLT 883
+ + ++H T
Sbjct: 252 DGRRFHRACRLVHDFT 267
>AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform
4F12 protein.
Length = 524
Score = 94.7 bits (225), Expect = 4e-19
Identities = 55/196 (28%), Positives = 97/196 (49%), Gaps = 7/196 (3%)
Frame = +2
Query: 317 RNIVQKSADYDHESVVKIWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEEY--RFFKPWL 487
++ Q SA Y V W+GP + + L P + I ++ I + RF KPWL
Sbjct: 75 KDSTQMSATYSQGFTV--WLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWL 132
Query: 488 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIELFNANSRAVVDK---LKKE-ASNFDCH 655
G G+L+S G KW HR+++ P FH N+LKS+I +FN ++ ++DK L E +S D
Sbjct: 133 GEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMF 192
Query: 656 DYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTD 835
+++S T++ L + Q++ EY ++++ ++ R I D L+ +
Sbjct: 193 EHISLMTLDSLQKCIFSFDSHCQERPS-EYIATILELSALVEKRSQHILQHMDFLYYLSH 251
Query: 836 YAKNQTKLLDIIHGLT 883
+ + ++H T
Sbjct: 252 DGRRFHRACRLVHDFT 267
>AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 94.7 bits (225), Expect = 4e-19
Identities = 55/196 (28%), Positives = 97/196 (49%), Gaps = 7/196 (3%)
Frame = +2
Query: 317 RNIVQKSADYDHESVVKIWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEEY--RFFKPWL 487
++ Q SA Y V W+GP + + L P + I ++ I + RF KPWL
Sbjct: 75 KDSTQMSATYSQGFTV--WLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWL 132
Query: 488 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIELFNANSRAVVDK---LKKE-ASNFDCH 655
G G+L+S G KW HR+++ P FH N+LKS+I +FN ++ ++DK L E +S D
Sbjct: 133 GEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMF 192
Query: 656 DYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTD 835
+++S T++ L + Q++ EY ++++ ++ R I D L+ +
Sbjct: 193 EHISLMTLDSLQKCIFSFDSHCQERPS-EYIATILELSALVEKRSQHILQHMDFLYYLSH 251
Query: 836 YAKNQTKLLDIIHGLT 883
+ + ++H T
Sbjct: 252 DGRRFHRACRLVHDFT 267
>AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 94.7 bits (225), Expect = 4e-19
Identities = 55/196 (28%), Positives = 97/196 (49%), Gaps = 7/196 (3%)
Frame = +2
Query: 317 RNIVQKSADYDHESVVKIWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEEY--RFFKPWL 487
++ Q SA Y V W+GP + + L P + I ++ I + RF KPWL
Sbjct: 75 KDSTQMSATYSQGFTV--WLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWL 132
Query: 488 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIELFNANSRAVVDK---LKKE-ASNFDCH 655
G G+L+S G KW HR+++ P FH N+LKS+I +FN ++ ++DK L E +S D
Sbjct: 133 GEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMF 192
Query: 656 DYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTD 835
+++S T++ L + Q++ EY ++++ ++ R I D L+ +
Sbjct: 193 EHISLMTLDSLQKCIFSFDSHCQERPS-EYIATILELSALVEKRSQHILQHMDFLYYLSH 251
Query: 836 YAKNQTKLLDIIHGLT 883
+ + ++H T
Sbjct: 252 DGRRFHRACRLVHDFT 267
>AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein.
Length = 520
Score = 92.7 bits (220), Expect = 2e-18
Identities = 71/247 (28%), Positives = 121/247 (48%), Gaps = 9/247 (3%)
Frame = +2
Query: 170 LVPAVILW-YAYWRMSRR-RLYELADKLNXXXXXXXXXNALEFVGGSADIFRNIVQKSAD 343
L+ ++ W YA++ RR R + K N L V + + R + Q A
Sbjct: 30 LLARILAWTYAFYHNGRRLRCFPQPRKQNWFLGH------LGLVTPTEEGLRVLTQLVAT 83
Query: 344 YDHESVVKIWIGPRL-LVFLYDPRDVE-VILSSHVYIDK-AEEYRFFKPWLGNGLLISTG 514
Y + V+ W+GP ++ L P V VI +S DK Y+ KPWLG+GLL+S G
Sbjct: 84 YP-QGFVR-WLGPITPIINLCHPDIVRSVINTSDAITDKDIVFYKTLKPWLGDGLLLSVG 141
Query: 515 QKWRSHRKLIAPTFHLNVLKSFIELFNANS---RAVVDKLKKEASN-FDCHDYMSECTVE 682
KWR HR+L+ P FH N+LK +I++F+ ++ A +L E S D +++S T++
Sbjct: 142 DKWRHHRRLLTPAFHFNILKPYIKIFSKSANIMHAKWQRLAMEGSTCLDVFEHISLMTLD 201
Query: 683 ILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLL 862
L + + Q++ EY A+M++ ++ R+ + + D L+ T + +
Sbjct: 202 SLQKCIFSFDSNCQEKPS-EYITAIMELSALVVKRNNQFFRYKDFLYFLTPCGRRFHRAC 260
Query: 863 DIIHGLT 883
++H T
Sbjct: 261 RLVHDFT 267
>BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 22 protein.
Length = 531
Score = 87.8 bits (208), Expect = 5e-17
Identities = 51/192 (26%), Positives = 102/192 (53%), Gaps = 7/192 (3%)
Frame = +2
Query: 329 QKSADYDHESVVKIWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGL 499
+K D H V+ +W+GP L L+ L P ++ +L + I ++ Y F KPWLG+GL
Sbjct: 86 KKVLDNMHH-VLLVWMGPVLPLLVLVHPDYIKPLLGASAAIAPKDDLFYGFLKPWLGDGL 144
Query: 500 LISTGQKWRSHRKLIAPTFHLNVLKSFIELFNANSRAVVDKLKK----EASNFDCHDYMS 667
L+S G KW HR+L+ P FH ++LK ++++FN ++ + K + A + D +++S
Sbjct: 145 LLSKGDKWSRHRRLLTPAFHFDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEHIS 204
Query: 668 ECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKN 847
T++ L + + + Q++ +Y A++++ + R ++ D ++ + +
Sbjct: 205 LMTLDSLQKCVFSYNSNCQEKMS-DYISAIIELSALSVRRQYRLHHYLDFIYYRSADGRR 263
Query: 848 QTKLLDIIHGLT 883
+ D++H T
Sbjct: 264 FRQACDMVHHFT 275
>BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 22 protein.
Length = 531
Score = 87.8 bits (208), Expect = 5e-17
Identities = 51/192 (26%), Positives = 102/192 (53%), Gaps = 7/192 (3%)
Frame = +2
Query: 329 QKSADYDHESVVKIWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGL 499
+K D H V+ +W+GP L L+ L P ++ +L + I ++ Y F KPWLG+GL
Sbjct: 86 KKVLDNMHH-VLLVWMGPVLPLLVLVHPDYIKPLLGASAAIAPKDDLFYGFLKPWLGDGL 144
Query: 500 LISTGQKWRSHRKLIAPTFHLNVLKSFIELFNANSRAVVDKLKK----EASNFDCHDYMS 667
L+S G KW HR+L+ P FH ++LK ++++FN ++ + K + A + D +++S
Sbjct: 145 LLSKGDKWSRHRRLLTPAFHFDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEHIS 204
Query: 668 ECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKN 847
T++ L + + + Q++ +Y A++++ + R ++ D ++ + +
Sbjct: 205 LMTLDSLQKCVFSYNSNCQEKMS-DYISAIIELSALSVRRQYRLHHYLDFIYYRSADGRR 263
Query: 848 QTKLLDIIHGLT 883
+ D++H T
Sbjct: 264 FRQACDMVHHFT 275
>BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 22 protein.
Length = 531
Score = 87.8 bits (208), Expect = 5e-17
Identities = 51/192 (26%), Positives = 102/192 (53%), Gaps = 7/192 (3%)
Frame = +2
Query: 329 QKSADYDHESVVKIWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGL 499
+K D H V+ +W+GP L L+ L P ++ +L + I ++ Y F KPWLG+GL
Sbjct: 86 KKVLDNMHH-VLLVWMGPVLPLLVLVHPDYIKPLLGASAAIAPKDDLFYGFLKPWLGDGL 144
Query: 500 LISTGQKWRSHRKLIAPTFHLNVLKSFIELFNANSRAVVDKLKK----EASNFDCHDYMS 667
L+S G KW HR+L+ P FH ++LK ++++FN ++ + K + A + D +++S
Sbjct: 145 LLSKGDKWSRHRRLLTPAFHFDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEHIS 204
Query: 668 ECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKN 847
T++ L + + + Q++ +Y A++++ + R ++ D ++ + +
Sbjct: 205 LMTLDSLQKCVFSYNSNCQEKMS-DYISAIIELSALSVRRQYRLHHYLDFIYYRSADGRR 263
Query: 848 QTKLLDIIHGLT 883
+ D++H T
Sbjct: 264 FRQACDMVHHFT 275
>AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens
cDNA FLJ39501 fis, clone PROST2016980, moderately
similar to CYTOCHROME P450 4F2 (EC 1.14.13.30). ).
Length = 531
Score = 85.8 bits (203), Expect = 2e-16
Identities = 50/192 (26%), Positives = 101/192 (52%), Gaps = 7/192 (3%)
Frame = +2
Query: 329 QKSADYDHESVVKIWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGL 499
+K D H V+ +W+GP L L+ L P ++ +L + ++ Y F KPWLG+GL
Sbjct: 86 KKVLDNMHH-VLLVWMGPVLPLLVLVHPDYIKPLLGASAATAPKDDLFYGFLKPWLGDGL 144
Query: 500 LISTGQKWRSHRKLIAPTFHLNVLKSFIELFNANSRAVVDKLKK----EASNFDCHDYMS 667
L+S G KW HR+L+ P FH ++LK ++++FN ++ + K + A + D +++S
Sbjct: 145 LLSKGDKWSRHRRLLTPAFHFDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEHIS 204
Query: 668 ECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKN 847
T++ L + + + Q++ +Y A++++ + R ++ D ++ + +
Sbjct: 205 LMTLDSLQKCVFSYNSNCQEKMS-DYISAIIELSALSVRRQYRLHHYLDFIYYRSADGRR 263
Query: 848 QTKLLDIIHGLT 883
+ D++H T
Sbjct: 264 FRQACDMVHHFT 275
>BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 85.4 bits (202), Expect = 2e-16
Identities = 52/179 (29%), Positives = 92/179 (51%), Gaps = 8/179 (4%)
Frame = +2
Query: 371 WIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEY--RFFKPWLGNGLLISTGQKWRSHRKL 541
WIGP F +YDP + +LS D +Y +F P LG GL G KW HR+L
Sbjct: 83 WIGPFQAFFCIYDPDYAKTLLSR---TDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRL 139
Query: 542 IAPTFHLNVLKSFIELFNANSRAVVDKLKKEASNFD----CHDYMSECTVEILLETAMGV 709
+ P FH N+LK++IE+ + + ++DK +K S D +++++ +++I+++ A
Sbjct: 140 LTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFSK 199
Query: 710 SKSTQDQSGFE-YAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 883
+ Q S + YA A+ ++ I+ R + D++FK + KL +++ T
Sbjct: 200 ETNCQTNSTHDPYAKAIFELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYT 258
>AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein.
Length = 509
Score = 85.4 bits (202), Expect = 2e-16
Identities = 52/179 (29%), Positives = 92/179 (51%), Gaps = 8/179 (4%)
Frame = +2
Query: 371 WIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEY--RFFKPWLGNGLLISTGQKWRSHRKL 541
WIGP F +YDP + +LS D +Y +F P LG GL G KW HR+L
Sbjct: 83 WIGPFQAFFCIYDPDYAKTLLSR---TDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRL 139
Query: 542 IAPTFHLNVLKSFIELFNANSRAVVDKLKKEASNFD----CHDYMSECTVEILLETAMGV 709
+ P FH N+LK++IE+ + + ++DK +K S D +++++ +++I+++ A
Sbjct: 140 LTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFSK 199
Query: 710 SKSTQDQSGFE-YAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 883
+ Q S + YA A+ ++ I+ R + D++FK + KL +++ T
Sbjct: 200 ETNCQTNSTHDPYAKAIFELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYT 258
>AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein.
Length = 509
Score = 85.4 bits (202), Expect = 2e-16
Identities = 52/179 (29%), Positives = 92/179 (51%), Gaps = 8/179 (4%)
Frame = +2
Query: 371 WIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEY--RFFKPWLGNGLLISTGQKWRSHRKL 541
WIGP F +YDP + +LS D +Y +F P LG GL G KW HR+L
Sbjct: 83 WIGPFQAFFCIYDPDYAKTLLSR---TDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRL 139
Query: 542 IAPTFHLNVLKSFIELFNANSRAVVDKLKKEASNFD----CHDYMSECTVEILLETAMGV 709
+ P FH N+LK++IE+ + + ++DK +K S D +++++ +++I+++ A
Sbjct: 140 LTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFSK 199
Query: 710 SKSTQDQSGFE-YAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 883
+ Q S + YA A+ ++ I+ R + D++FK + KL +++ T
Sbjct: 200 ETNCQTNSTHDPYAKAIFELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYT 258
>AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 85.4 bits (202), Expect = 2e-16
Identities = 52/179 (29%), Positives = 92/179 (51%), Gaps = 8/179 (4%)
Frame = +2
Query: 371 WIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEY--RFFKPWLGNGLLISTGQKWRSHRKL 541
WIGP F +YDP + +LS D +Y +F P LG GL G KW HR+L
Sbjct: 83 WIGPFQAFFCIYDPDYAKTLLSR---TDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRL 139
Query: 542 IAPTFHLNVLKSFIELFNANSRAVVDKLKKEASNFD----CHDYMSECTVEILLETAMGV 709
+ P FH N+LK++IE+ + + ++DK +K S D +++++ +++I+++ A
Sbjct: 140 LTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFSK 199
Query: 710 SKSTQDQSGFE-YAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 883
+ Q S + YA A+ ++ I+ R + D++FK + KL +++ T
Sbjct: 200 ETNCQTNSTHDPYAKAIFELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYT 258
>AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens
cDNA FLJ40746 fis, clone TRACH2000359, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 509
Score = 85.4 bits (202), Expect = 2e-16
Identities = 52/179 (29%), Positives = 92/179 (51%), Gaps = 8/179 (4%)
Frame = +2
Query: 371 WIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEY--RFFKPWLGNGLLISTGQKWRSHRKL 541
WIGP F +YDP + +LS D +Y +F P LG GL G KW HR+L
Sbjct: 83 WIGPFQAFFCIYDPDYAKTLLSR---TDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRL 139
Query: 542 IAPTFHLNVLKSFIELFNANSRAVVDKLKKEASNFD----CHDYMSECTVEILLETAMGV 709
+ P FH N+LK++IE+ + + ++DK +K S D +++++ +++I+++ A
Sbjct: 140 LTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFSK 199
Query: 710 SKSTQDQSGFE-YAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 883
+ Q S + YA A+ ++ I+ R + D++FK + KL +++ T
Sbjct: 200 ETNCQTNSTHDPYAKAIFELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYT 258
>AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens
cDNA FLJ34487 fis, clone HLUNG2004273, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 444
Score = 85.4 bits (202), Expect = 2e-16
Identities = 52/179 (29%), Positives = 92/179 (51%), Gaps = 8/179 (4%)
Frame = +2
Query: 371 WIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEY--RFFKPWLGNGLLISTGQKWRSHRKL 541
WIGP F +YDP + +LS D +Y +F P LG GL G KW HR+L
Sbjct: 18 WIGPFQAFFCIYDPDYAKTLLSR---TDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRL 74
Query: 542 IAPTFHLNVLKSFIELFNANSRAVVDKLKKEASNFD----CHDYMSECTVEILLETAMGV 709
+ P FH N+LK++IE+ + + ++DK +K S D +++++ +++I+++ A
Sbjct: 75 LTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFSK 134
Query: 710 SKSTQDQSGFE-YAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 883
+ Q S + YA A+ ++ I+ R + D++FK + KL +++ T
Sbjct: 135 ETNCQTNSTHDPYAKAIFELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYT 193
>AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens
cDNA FLJ16384 fis, clone TLIVE2007607, weakly similar
to CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 508
Score = 85.0 bits (201), Expect = 3e-16
Identities = 52/179 (29%), Positives = 92/179 (51%), Gaps = 8/179 (4%)
Frame = +2
Query: 371 WIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEY--RFFKPWLGNGLLISTGQKWRSHRKL 541
WIGP F +YDP + +LS D +Y +F P LG GL G KW HR+L
Sbjct: 82 WIGPFQAFFCIYDPDYAKTLLSR---TDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRL 138
Query: 542 IAPTFHLNVLKSFIELFNANSRAVVDKLKKEASNFD----CHDYMSECTVEILLETAMGV 709
+ P FH N+LK++IE+ + + ++DK +K S D +++++ +++I+++ A
Sbjct: 139 LTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIVMKCAFSK 198
Query: 710 SKSTQDQSGFE-YAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 883
+ Q S + YA A+ ++ I+ R + D++FK + KL +++ T
Sbjct: 199 ETNCQTNSTHDPYAKAIFELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYT 257
>AK097373-1|BAC05026.1| 340|Homo sapiens protein ( Homo sapiens
cDNA FLJ40054 fis, clone TBAES2000315, weakly similar to
CYTOCHROME P450 4A1 (EC 1.14.15.3). ).
Length = 340
Score = 82.6 bits (195), Expect = 2e-15
Identities = 47/179 (26%), Positives = 93/179 (51%), Gaps = 5/179 (2%)
Frame = +2
Query: 362 VKIWIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRK 538
V +W+GP + F ++DP V+++L A ++ + W+G GL+ G KW+ HR+
Sbjct: 80 VPLWVGPFTMFFNIHDPDYVKILLKRQDP-KSAVSHKILESWVGRGLVTLDGSKWKKHRQ 138
Query: 539 LIAPTFHLNVLKSFIELFNANSRAVVDKLKK---EASNFDCHDYMSECTVEILLETAMGV 709
++ P F++++LK FI + + + R +++K ++ + S + ++S T++ +++ A
Sbjct: 139 IVKPGFNISILKIFITMMSKSVRMMLNKWEEHIAQNSRLELFQHVSLMTLDSIMKCAFSH 198
Query: 710 SKSTQ-DQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 883
S Q D + Y AV + I + R DL+FKF+ + +K +H T
Sbjct: 199 QGSIQLDSTLDSYLKAVFNLSKISNQRMNNFLHHNDLVFKFSSQGQIFSKFNQELHQFT 257
>AY696295-1|AAU10524.1| 292|Homo sapiens cytochrome P450 protein.
Length = 292
Score = 81.8 bits (193), Expect = 3e-15
Identities = 47/179 (26%), Positives = 91/179 (50%), Gaps = 5/179 (2%)
Frame = +2
Query: 362 VKIWIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRK 538
V +W+GP + F ++DP V+++L A ++ + W+G GL+ G KW+ HR+
Sbjct: 80 VPLWVGPFTMFFNIHDPDYVKILLKRQ-NPKSAVSHKILESWVGRGLVTLDGSKWKKHRQ 138
Query: 539 LIAPTFHLNVLKSFIELFNANSRAVVDKLKKEA---SNFDCHDYMSECTVEILLETAMGV 709
++ P F++++LK FI + + + R +++K ++ S + ++S T+ +++ A
Sbjct: 139 IVKPGFNISILKIFITMMSKSVRMMLNKWEEHIAHNSRLELFQHVSLMTLHSIMKCAFSH 198
Query: 710 SKSTQ-DQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 883
S Q D + Y AV + I + R DL+FKF+ + +K +H T
Sbjct: 199 QGSIQLDSTLDSYLKAVFNLSKISNQRMNNFLHHNDLVFKFSSQGQIFSKFNQELHQFT 257
>AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein.
Length = 505
Score = 81.4 bits (192), Expect = 4e-15
Identities = 48/179 (26%), Positives = 91/179 (50%), Gaps = 5/179 (2%)
Frame = +2
Query: 362 VKIWIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRK 538
V +W+GP + F ++DP D IL A ++ + W+G GL+ G KW+ HR+
Sbjct: 80 VPLWVGPFTMFFSVHDP-DYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKKHRQ 138
Query: 539 LIAPTFHLNVLKSFIELFNANSRAVVDKLKK---EASNFDCHDYMSECTVEILLETAMGV 709
++ P F++++LK FI + + + R +++K ++ + S + ++S T++ +++ A
Sbjct: 139 IVKPGFNISILKIFITMMSESVRMMLNKWEEHIAQNSRLELFQHVSLMTLDSIMKCAFSH 198
Query: 710 SKSTQ-DQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 883
S Q D + Y AV + I + R DL+FKF+ + +K +H T
Sbjct: 199 QGSIQLDSTLDSYLKAVFNLSKISNQRMNNFLHHNDLVFKFSSQGQIFSKFNQELHQFT 257
>AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein.
Length = 505
Score = 81.4 bits (192), Expect = 4e-15
Identities = 48/179 (26%), Positives = 91/179 (50%), Gaps = 5/179 (2%)
Frame = +2
Query: 362 VKIWIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRK 538
V +W+GP + F ++DP D IL A ++ + W+G GL+ G KW+ HR+
Sbjct: 80 VPLWVGPFTMFFSVHDP-DYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKKHRQ 138
Query: 539 LIAPTFHLNVLKSFIELFNANSRAVVDKLKK---EASNFDCHDYMSECTVEILLETAMGV 709
++ P F++++LK FI + + + R +++K ++ + S + ++S T++ +++ A
Sbjct: 139 IVKPGFNISILKIFITMMSESVRMMLNKWEEHIAQNSRLELFQHVSLMTLDSIMKCAFSH 198
Query: 710 SKSTQ-DQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 883
S Q D + Y AV + I + R DL+FKF+ + +K +H T
Sbjct: 199 QGSIQLDSTLDSYLKAVFNLSKISNQRMNNFLHHNDLVFKFSSQGQIFSKFNQELHQFT 257
>AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 81.4 bits (192), Expect = 4e-15
Identities = 48/179 (26%), Positives = 91/179 (50%), Gaps = 5/179 (2%)
Frame = +2
Query: 362 VKIWIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRK 538
V +W+GP + F ++DP D IL A ++ + W+G GL+ G KW+ HR+
Sbjct: 80 VPLWVGPFTMFFSVHDP-DYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKKHRQ 138
Query: 539 LIAPTFHLNVLKSFIELFNANSRAVVDKLKK---EASNFDCHDYMSECTVEILLETAMGV 709
++ P F++++LK FI + + + R +++K ++ + S + ++S T++ +++ A
Sbjct: 139 IVKPGFNISILKIFITMMSESVRMMLNKWEEHIAQNSRLELFQHVSLMTLDSIMKCAFSH 198
Query: 710 SKSTQ-DQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 883
S Q D + Y AV + I + R DL+FKF+ + +K +H T
Sbjct: 199 QGSIQLDSTLDSYLKAVFNLSKISNQRMNNFLHHNDLVFKFSSQGQIFSKFNQELHQFT 257
>AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 81.4 bits (192), Expect = 4e-15
Identities = 48/179 (26%), Positives = 91/179 (50%), Gaps = 5/179 (2%)
Frame = +2
Query: 362 VKIWIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRK 538
V +W+GP + F ++DP D IL A ++ + W+G GL+ G KW+ HR+
Sbjct: 80 VPLWVGPFTMFFSVHDP-DYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKKHRQ 138
Query: 539 LIAPTFHLNVLKSFIELFNANSRAVVDKLKK---EASNFDCHDYMSECTVEILLETAMGV 709
++ P F++++LK FI + + + R +++K ++ + S + ++S T++ +++ A
Sbjct: 139 IVKPGFNISILKIFITMMSESVRMMLNKWEEHIAQNSRLELFQHVSLMTLDSIMKCAFSH 198
Query: 710 SKSTQ-DQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 883
S Q D + Y AV + I + R DL+FKF+ + +K +H T
Sbjct: 199 QGSIQLDSTLDSYLKAVFNLSKISNQRMNNFLHHNDLVFKFSSQGQIFSKFNQELHQFT 257
>S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 591
Score = 80.6 bits (190), Expect = 7e-15
Identities = 47/173 (27%), Positives = 87/173 (50%), Gaps = 5/173 (2%)
Frame = +2
Query: 371 WI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIA 547
W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++
Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLT 147
Query: 548 PTFHLNVLKSFIELFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAMGVSKS 718
P FH ++LK ++ L + R ++DK L + S + ++S T++ +++ A S
Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGS 207
Query: 719 TQ-DQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIH 874
Q D++ Y A+ + +++ R + + D ++ T + + + H
Sbjct: 208 IQVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAH 260
>S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 519
Score = 80.6 bits (190), Expect = 7e-15
Identities = 47/173 (27%), Positives = 87/173 (50%), Gaps = 5/173 (2%)
Frame = +2
Query: 371 WI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIA 547
W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++
Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLT 147
Query: 548 PTFHLNVLKSFIELFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAMGVSKS 718
P FH ++LK ++ L + R ++DK L + S + ++S T++ +++ A S
Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGS 207
Query: 719 TQ-DQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIH 874
Q D++ Y A+ + +++ R + + D ++ T + + + H
Sbjct: 208 IQVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAH 260
>L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein.
Length = 519
Score = 80.6 bits (190), Expect = 7e-15
Identities = 47/173 (27%), Positives = 87/173 (50%), Gaps = 5/173 (2%)
Frame = +2
Query: 371 WI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIA 547
W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++
Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLT 147
Query: 548 PTFHLNVLKSFIELFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAMGVSKS 718
P FH ++LK ++ L + R ++DK L + S + ++S T++ +++ A S
Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGS 207
Query: 719 TQ-DQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIH 874
Q D++ Y A+ + +++ R + + D ++ T + + + H
Sbjct: 208 IQVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAH 260
>D26481-1|BAA05491.1| 519|Homo sapiens fatty acids
omega-hydroxylase protein.
Length = 519
Score = 80.6 bits (190), Expect = 7e-15
Identities = 47/173 (27%), Positives = 87/173 (50%), Gaps = 5/173 (2%)
Frame = +2
Query: 371 WI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIA 547
W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++
Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLT 147
Query: 548 PTFHLNVLKSFIELFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAMGVSKS 718
P FH ++LK ++ L + R ++DK L + S + ++S T++ +++ A S
Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGS 207
Query: 719 TQ-DQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIH 874
Q D++ Y A+ + +++ R + + D ++ T + + + H
Sbjct: 208 IQVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAH 260
>BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein.
Length = 455
Score = 80.6 bits (190), Expect = 7e-15
Identities = 47/173 (27%), Positives = 87/173 (50%), Gaps = 5/173 (2%)
Frame = +2
Query: 371 WI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIA 547
W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++
Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLT 147
Query: 548 PTFHLNVLKSFIELFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAMGVSKS 718
P FH ++LK ++ L + R ++DK L + S + ++S T++ +++ A S
Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGS 207
Query: 719 TQ-DQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIH 874
Q D++ Y A+ + +++ R + + D ++ T + + + H
Sbjct: 208 IQVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAH 260
>AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 80.6 bits (190), Expect = 7e-15
Identities = 47/173 (27%), Positives = 87/173 (50%), Gaps = 5/173 (2%)
Frame = +2
Query: 371 WI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIA 547
W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++
Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLT 147
Query: 548 PTFHLNVLKSFIELFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAMGVSKS 718
P FH ++LK ++ L + R ++DK L + S + ++S T++ +++ A S
Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGS 207
Query: 719 TQ-DQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIH 874
Q D++ Y A+ + +++ R + + D ++ T + + + H
Sbjct: 208 IQVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAH 260
>AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 455
Score = 80.6 bits (190), Expect = 7e-15
Identities = 47/173 (27%), Positives = 87/173 (50%), Gaps = 5/173 (2%)
Frame = +2
Query: 371 WI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIA 547
W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++
Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLT 147
Query: 548 PTFHLNVLKSFIELFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAMGVSKS 718
P FH ++LK ++ L + R ++DK L + S + ++S T++ +++ A S
Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGS 207
Query: 719 TQ-DQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIH 874
Q D++ Y A+ + +++ R + + D ++ T + + + H
Sbjct: 208 IQVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAH 260
>AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 80.6 bits (190), Expect = 7e-15
Identities = 47/173 (27%), Positives = 87/173 (50%), Gaps = 5/173 (2%)
Frame = +2
Query: 371 WI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIA 547
W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++
Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLT 147
Query: 548 PTFHLNVLKSFIELFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAMGVSKS 718
P FH ++LK ++ L + R ++DK L + S + ++S T++ +++ A S
Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGS 207
Query: 719 TQ-DQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIH 874
Q D++ Y A+ + +++ R + + D ++ T + + + H
Sbjct: 208 IQVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAH 260
>AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfamily
IVA, polypeptide 11 protein.
Length = 519
Score = 80.6 bits (190), Expect = 7e-15
Identities = 47/173 (27%), Positives = 87/173 (50%), Gaps = 5/173 (2%)
Frame = +2
Query: 371 WI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIA 547
W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++
Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLT 147
Query: 548 PTFHLNVLKSFIELFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAMGVSKS 718
P FH ++LK ++ L + R ++DK L + S + ++S T++ +++ A S
Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGS 207
Query: 719 TQ-DQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIH 874
Q D++ Y A+ + +++ R + + D ++ T + + + H
Sbjct: 208 IQVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAH 260
>D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 521
Score = 80.2 bits (189), Expect = 9e-15
Identities = 47/173 (27%), Positives = 87/173 (50%), Gaps = 5/173 (2%)
Frame = +2
Query: 371 WI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIA 547
W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++
Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLT 147
Query: 548 PTFHLNVLKSFIELFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAMGVSKS 718
P FH ++LK ++ L + R ++DK L + S + ++S T++ +++ A S
Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGS 207
Query: 719 TQ-DQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIH 874
Q D++ Y A+ + +++ R + + D ++ T + + + H
Sbjct: 208 IQVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLSH 260
>AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22
protein.
Length = 519
Score = 79.8 bits (188), Expect = 1e-14
Identities = 47/178 (26%), Positives = 86/178 (48%), Gaps = 5/178 (2%)
Frame = +2
Query: 356 SVVKIWI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSH 532
S WI G ++ V LYDP ++VIL Y+F PW+G LL+ GQ W H
Sbjct: 84 SACPYWIWGGKVRVQLYDPDYMKVILGRSDSKSHGS-YKFLAPWIGYSLLLLNGQTWFQH 142
Query: 533 RKLIAPTFHLNVLKSFIELFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAM 703
R+++ P FH ++LK ++ L + R ++DK L + S + ++S T++ ++++A
Sbjct: 143 RRMLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEFFQHVSLMTLDTIMKSAF 202
Query: 704 GVSKSTQ-DQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIH 874
S Q D++ Y A+ + ++ R + D ++ T + + + H
Sbjct: 203 SHQGSIQVDRNSQSYIQAISDLSSLVFCRMRNAFHENDAIYSLTSAGRWTHRACQLAH 260
>BC142607-1|AAI42608.1| 455|Homo sapiens CYP4A22 protein protein.
Length = 455
Score = 78.6 bits (185), Expect = 3e-14
Identities = 47/178 (26%), Positives = 86/178 (48%), Gaps = 5/178 (2%)
Frame = +2
Query: 356 SVVKIWI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSH 532
S WI G ++ V LYDP ++VIL Y+F PW+G LL+ GQ W H
Sbjct: 84 SACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YKFLAPWIGYSLLLLNGQTWFQH 142
Query: 533 RKLIAPTFHLNVLKSFIELFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAM 703
R+++ P FH ++LK ++ L + R ++DK L + S + ++S T++ ++++A
Sbjct: 143 RRMLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEFFQHVSLMTLDTIMKSAF 202
Query: 704 GVSKSTQ-DQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIH 874
S Q D++ Y A+ + ++ R + D ++ T + + + H
Sbjct: 203 SHQGSIQVDRNSQSYIQAISDLNSLVFCRMRNAFHENDTIYSLTSAGRWTHRACQLAH 260
>AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K
protein.
Length = 519
Score = 78.6 bits (185), Expect = 3e-14
Identities = 47/178 (26%), Positives = 88/178 (49%), Gaps = 5/178 (2%)
Frame = +2
Query: 356 SVVKIWI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSH 532
S WI G ++ V LYDP ++VIL Y+F PW+G LL+ GQ W H
Sbjct: 84 SACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YKFLAPWIGYSLLLLNGQTWFQH 142
Query: 533 RKLIAPTFHLNVLKSFIELFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAM 703
R+++ P FH ++LK ++ L + R ++DK L + S + ++S T++ ++++A
Sbjct: 143 RRMLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEFFQHVSLMTLDTIMKSAF 202
Query: 704 GVSKSTQ-DQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIH 874
S Q D++ Y A+ + +++ R + + D ++ T + + + H
Sbjct: 203 SHQGSIQVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAH 260
>J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung
cytochrome P450 (IV subfamily) BI protein, complete cds.
).
Length = 511
Score = 77.8 bits (183), Expect = 5e-14
Identities = 62/256 (24%), Positives = 113/256 (44%), Gaps = 7/256 (2%)
Frame = +2
Query: 137 TFSAINLFYVLLVPAV-ILWYAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVG-GSAD 310
+FS++ L+ L+ + L + + RR L + DK +ALE GS D
Sbjct: 9 SFSSLGLWASGLILVLGFLKLIHLLLRRRTLAKAMDKFPGPPTHWLFGHALEIQETGSLD 68
Query: 311 IFRNIVQKSADYDHESVVKIWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE-YRFFKPW 484
+V + + + +W G + + +Y+P + + S KA + Y FF W
Sbjct: 69 ---KVVSWAHQFPYAH--PLWFGQFIGFLNIYEPDYAKAVYSRGD--PKAPDVYDFFLQW 121
Query: 485 LGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIELFNANSRAVVDKLK---KEASNFDCH 655
+G GLL+ G KW HRKL+ P FH +VLK ++ +F ++R ++DK + +E +FD
Sbjct: 122 IGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIF 181
Query: 656 DYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTD 835
+ + L++ G + Y +AV + ++ R D ++ T
Sbjct: 182 CDVGHMALNTLMKCTFGRGDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTP 241
Query: 836 YAKNQTKLLDIIHGLT 883
+ + + + H T
Sbjct: 242 HGRRFLRACQVAHDHT 257
>X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for
cytochrome P-450HP. ).
Length = 511
Score = 77.4 bits (182), Expect = 6e-14
Identities = 45/177 (25%), Positives = 82/177 (46%), Gaps = 5/177 (2%)
Frame = +2
Query: 368 IWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE-YRFFKPWLGNGLLISTGQKWRSHRKL 541
+W G + + +Y+P + + S KA + Y FF W+G GLL+ G KW HRKL
Sbjct: 83 LWFGQFIGFLNIYEPDYAKAVYSRGD--PKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKL 140
Query: 542 IAPTFHLNVLKSFIELFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETAMGVS 712
+ P FH +VLK ++ +F ++R ++DK + +E +FD + + L++ G
Sbjct: 141 LTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGRG 200
Query: 713 KSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 883
+ Y +AV + ++ R D ++ T + + + + H T
Sbjct: 201 DTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHT 257
>DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 77.4 bits (182), Expect = 6e-14
Identities = 45/177 (25%), Positives = 82/177 (46%), Gaps = 5/177 (2%)
Frame = +2
Query: 368 IWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE-YRFFKPWLGNGLLISTGQKWRSHRKL 541
+W G + + +Y+P + + S KA + Y FF W+G GLL+ G KW HRKL
Sbjct: 83 LWFGQFIGFLNIYEPDYAKAVYSRGD--PKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKL 140
Query: 542 IAPTFHLNVLKSFIELFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETAMGVS 712
+ P FH +VLK ++ +F ++R ++DK + +E +FD + + L++ G
Sbjct: 141 LTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGRG 200
Query: 713 KSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 883
+ Y +AV + ++ R D ++ T + + + + H T
Sbjct: 201 DTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHT 257
>AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 77.4 bits (182), Expect = 6e-14
Identities = 45/177 (25%), Positives = 82/177 (46%), Gaps = 5/177 (2%)
Frame = +2
Query: 368 IWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE-YRFFKPWLGNGLLISTGQKWRSHRKL 541
+W G + + +Y+P + + S KA + Y FF W+G GLL+ G KW HRKL
Sbjct: 83 LWFGQFIGFLNIYEPDYAKAVYSRGD--PKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKL 140
Query: 542 IAPTFHLNVLKSFIELFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETAMGVS 712
+ P FH +VLK ++ +F ++R ++DK + +E +FD + + L++ G
Sbjct: 141 LTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGRG 200
Query: 713 KSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 883
+ Y +AV + ++ R D ++ T + + + + H T
Sbjct: 201 DTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHT 257
>AY064484-1|AAL57719.1| 295|Homo sapiens truncated cytochrome P450
protein.
Length = 295
Score = 77.4 bits (182), Expect = 6e-14
Identities = 45/177 (25%), Positives = 82/177 (46%), Gaps = 5/177 (2%)
Frame = +2
Query: 368 IWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE-YRFFKPWLGNGLLISTGQKWRSHRKL 541
+W G + + +Y+P + + S KA + Y FF W+G GLL+ G KW HRKL
Sbjct: 83 LWFGQFIGFLNIYEPDYAKAVYSRGD--PKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKL 140
Query: 542 IAPTFHLNVLKSFIELFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETAMGVS 712
+ P FH +VLK ++ +F ++R ++DK + +E +FD + + L++ G
Sbjct: 141 LTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGRG 200
Query: 713 KSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 883
+ Y +AV + ++ R D ++ T + + + + H T
Sbjct: 201 DTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHT 257
>AL593856-6|CAI16981.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 77.4 bits (182), Expect = 6e-14
Identities = 45/177 (25%), Positives = 82/177 (46%), Gaps = 5/177 (2%)
Frame = +2
Query: 368 IWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE-YRFFKPWLGNGLLISTGQKWRSHRKL 541
+W G + + +Y+P + + S KA + Y FF W+G GLL+ G KW HRKL
Sbjct: 83 LWFGQFIGFLNIYEPDYAKAVYSRGD--PKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKL 140
Query: 542 IAPTFHLNVLKSFIELFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETAMGVS 712
+ P FH +VLK ++ +F ++R ++DK + +E +FD + + L++ G
Sbjct: 141 LTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGRG 200
Query: 713 KSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 883
+ Y +AV + ++ R D ++ T + + + + H T
Sbjct: 201 DTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHT 257
>AL356793-3|CAI22559.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 77.4 bits (182), Expect = 6e-14
Identities = 45/177 (25%), Positives = 82/177 (46%), Gaps = 5/177 (2%)
Frame = +2
Query: 368 IWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE-YRFFKPWLGNGLLISTGQKWRSHRKL 541
+W G + + +Y+P + + S KA + Y FF W+G GLL+ G KW HRKL
Sbjct: 83 LWFGQFIGFLNIYEPDYAKAVYSRGD--PKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKL 140
Query: 542 IAPTFHLNVLKSFIELFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETAMGVS 712
+ P FH +VLK ++ +F ++R ++DK + +E +FD + + L++ G
Sbjct: 141 LTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGRG 200
Query: 713 KSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 883
+ Y +AV + ++ R D ++ T + + + + H T
Sbjct: 201 DTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHT 257
>AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 77.4 bits (182), Expect = 6e-14
Identities = 45/177 (25%), Positives = 82/177 (46%), Gaps = 5/177 (2%)
Frame = +2
Query: 368 IWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE-YRFFKPWLGNGLLISTGQKWRSHRKL 541
+W G + + +Y+P + + S KA + Y FF W+G GLL+ G KW HRKL
Sbjct: 83 LWFGQFIGFLNIYEPDYAKAVYSRGD--PKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKL 140
Query: 542 IAPTFHLNVLKSFIELFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETAMGVS 712
+ P FH +VLK ++ +F ++R ++DK + +E +FD + + L++ G
Sbjct: 141 LTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGRG 200
Query: 713 KSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 883
+ Y +AV + ++ R D ++ T + + + + H T
Sbjct: 201 DTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHT 257
>AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 77.0 bits (181), Expect = 9e-14
Identities = 45/177 (25%), Positives = 82/177 (46%), Gaps = 5/177 (2%)
Frame = +2
Query: 368 IWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE-YRFFKPWLGNGLLISTGQKWRSHRKL 541
+W G + + +Y+P + + S KA + Y FF W+G GLL+ G KW HRKL
Sbjct: 83 LWFGQFIGFLNIYEPDYAKAVYSRGD--PKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKL 140
Query: 542 IAPTFHLNVLKSFIELFNANSRAVVDKLKK---EASNFDCHDYMSECTVEILLETAMGVS 712
+ P FH +VLK ++ +F ++R ++DK ++ E +FD + + L++ G
Sbjct: 141 LTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAWEGKSFDIFCDVGHMALNTLMKCTFGRG 200
Query: 713 KSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 883
+ Y +AV + ++ R D ++ T + + + + H T
Sbjct: 201 DTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHT 257
>AF221943-1|AAF86378.1| 175|Homo sapiens leukotriene B4 omega
hydroxylase protein.
Length = 175
Score = 75.4 bits (177), Expect = 3e-13
Identities = 31/80 (38%), Positives = 52/80 (65%), Gaps = 3/80 (3%)
Frame = +2
Query: 365 KIWIGP-RLLVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHR 535
K+W+GP L+ L P + ++++ I ++ Y F +PWLG+GLL+S G KW HR
Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148
Query: 536 KLIAPTFHLNVLKSFIELFN 595
+++ P FH N+LK ++++FN
Sbjct: 149 RMLTPAFHFNILKPYMKIFN 168
>BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 74.9 bits (176), Expect = 3e-13
Identities = 46/178 (25%), Positives = 83/178 (46%), Gaps = 6/178 (3%)
Frame = +2
Query: 368 IWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE-YRFFKPWLGNGLLISTGQKWRSHRKL 541
+W G + + +Y+P + + S KA + Y FF W+G GLL+ G KW HRKL
Sbjct: 83 LWFGQFIGFLNIYEPDYAKAVYSRGD--PKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKL 140
Query: 542 IAPTFHLNVLKSFIELFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETAMGVS 712
+ P FH +VLK ++ +F ++R ++DK + +E +FD + + L++ G
Sbjct: 141 LTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGRG 200
Query: 713 KSTQDQS-GFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 883
+ S Y +AV + ++ R D ++ T + + + + H T
Sbjct: 201 DTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHT 258
>AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P450
4B1 protein.
Length = 512
Score = 74.9 bits (176), Expect = 3e-13
Identities = 46/178 (25%), Positives = 83/178 (46%), Gaps = 6/178 (3%)
Frame = +2
Query: 368 IWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE-YRFFKPWLGNGLLISTGQKWRSHRKL 541
+W G + + +Y+P + + S KA + Y FF W+G GLL+ G KW HRKL
Sbjct: 83 LWFGQFIGFLNIYEPDYAKAVYSRGD--PKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKL 140
Query: 542 IAPTFHLNVLKSFIELFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETAMGVS 712
+ P FH +VLK ++ +F ++R ++DK + +E +FD + + L++ G
Sbjct: 141 LTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGRG 200
Query: 713 KSTQDQS-GFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 883
+ S Y +AV + ++ R D ++ T + + + + H T
Sbjct: 201 DTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHT 258
>AL593856-7|CAI16982.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 74.9 bits (176), Expect = 3e-13
Identities = 46/178 (25%), Positives = 83/178 (46%), Gaps = 6/178 (3%)
Frame = +2
Query: 368 IWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE-YRFFKPWLGNGLLISTGQKWRSHRKL 541
+W G + + +Y+P + + S KA + Y FF W+G GLL+ G KW HRKL
Sbjct: 83 LWFGQFIGFLNIYEPDYAKAVYSRGD--PKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKL 140
Query: 542 IAPTFHLNVLKSFIELFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETAMGVS 712
+ P FH +VLK ++ +F ++R ++DK + +E +FD + + L++ G
Sbjct: 141 LTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGRG 200
Query: 713 KSTQDQS-GFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 883
+ S Y +AV + ++ R D ++ T + + + + H T
Sbjct: 201 DTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHT 258
>AL356793-4|CAI22557.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 74.9 bits (176), Expect = 3e-13
Identities = 46/178 (25%), Positives = 83/178 (46%), Gaps = 6/178 (3%)
Frame = +2
Query: 368 IWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE-YRFFKPWLGNGLLISTGQKWRSHRKL 541
+W G + + +Y+P + + S KA + Y FF W+G GLL+ G KW HRKL
Sbjct: 83 LWFGQFIGFLNIYEPDYAKAVYSRGD--PKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKL 140
Query: 542 IAPTFHLNVLKSFIELFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETAMGVS 712
+ P FH +VLK ++ +F ++R ++DK + +E +FD + + L++ G
Sbjct: 141 LTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGRG 200
Query: 713 KSTQDQS-GFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 883
+ S Y +AV + ++ R D ++ T + + + + H T
Sbjct: 201 DTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHT 258
>AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid
omega-hydroxylase CYP4A11 protein.
Length = 519
Score = 72.9 bits (171), Expect = 1e-12
Identities = 47/178 (26%), Positives = 85/178 (47%), Gaps = 5/178 (2%)
Frame = +2
Query: 356 SVVKIWI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSH 532
S WI G ++ V LYDP ++VIL YRF P +G GLL+ GQ W H
Sbjct: 84 SACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPRIGYGLLLLNGQTWFQH 142
Query: 533 RKLIAPTFHLNVLKSFIELFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAM 703
R+++ P FH ++LK ++ L + R ++DK L + S + ++S T++ ++++A
Sbjct: 143 RRMLTPAFHNDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKSAF 202
Query: 704 GVSKSTQ-DQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIH 874
S Q D++ Y A+ + ++ + D ++ T + + + H
Sbjct: 203 SHQGSIQVDRNSQSYIQAISDLNSLVFCCMRNAFHENDTIYSLTSAGRWTHRACQLAH 260
>BC022851-1|AAH22851.1| 215|Homo sapiens CYP4A11 protein protein.
Length = 215
Score = 71.7 bits (168), Expect = 3e-12
Identities = 38/114 (33%), Positives = 64/114 (56%), Gaps = 4/114 (3%)
Frame = +2
Query: 371 WI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIA 547
W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++
Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLT 147
Query: 548 PTFHLNVLKSFIELFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETA 700
P FH ++LK ++ L + R ++DK L + S + ++S T++ +++ A
Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCA 201
>AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, family
4, subfamily A, polypeptide 22 protein.
Length = 455
Score = 71.7 bits (168), Expect = 3e-12
Identities = 46/178 (25%), Positives = 85/178 (47%), Gaps = 5/178 (2%)
Frame = +2
Query: 356 SVVKIWI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSH 532
S WI G ++ V LYDP ++VIL Y+F P +G GLL+ GQ W H
Sbjct: 84 SACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YKFLAPRIGYGLLLLNGQTWFQH 142
Query: 533 RKLIAPTFHLNVLKSFIELFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAM 703
R+++ P FH ++LK ++ L + R ++DK L + S + ++S T++ ++++A
Sbjct: 143 RRMLTPAFHNDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKSAF 202
Query: 704 GVSKSTQ-DQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIH 874
S Q D++ Y A+ + ++ + D ++ T + + + H
Sbjct: 203 SHQGSIQVDRNSQSYIQAISDLNSLVFCCMRNAFHENDTIYSLTSAGRWTHRACQLAH 260
>AL135960-9|CAI19737.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 22 protein.
Length = 519
Score = 71.7 bits (168), Expect = 3e-12
Identities = 46/178 (25%), Positives = 85/178 (47%), Gaps = 5/178 (2%)
Frame = +2
Query: 356 SVVKIWI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSH 532
S WI G ++ V LYDP ++VIL Y+F P +G GLL+ GQ W H
Sbjct: 84 SACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YKFLAPRIGYGLLLLNGQTWFQH 142
Query: 533 RKLIAPTFHLNVLKSFIELFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAM 703
R+++ P FH ++LK ++ L + R ++DK L + S + ++S T++ ++++A
Sbjct: 143 RRMLTPAFHNDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKSAF 202
Query: 704 GVSKSTQ-DQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIH 874
S Q D++ Y A+ + ++ + D ++ T + + + H
Sbjct: 203 SHQGSIQVDRNSQSYIQAISDLNSLVFCCMRNAFHENDTIYSLTSAGRWTHRACQLAH 260
>BC142690-1|AAI42691.1| 357|Homo sapiens CYP4A22 protein protein.
Length = 357
Score = 68.1 bits (159), Expect = 4e-11
Identities = 40/127 (31%), Positives = 67/127 (52%), Gaps = 4/127 (3%)
Frame = +2
Query: 356 SVVKIWI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSH 532
S WI G ++ V LYDP ++VIL Y+F P +G GLL+ GQ W H
Sbjct: 84 SACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YKFLAPRIGYGLLLLNGQTWFQH 142
Query: 533 RKLIAPTFHLNVLKSFIELFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAM 703
R+++ P FH ++LK ++ L + R ++DK L + S + ++S T++ ++++A
Sbjct: 143 RRMLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKSAF 202
Query: 704 GVSKSTQ 724
S Q
Sbjct: 203 SHQGSIQ 209
>AL135960-10|CAI19736.1| 421|Homo sapiens cytochrome P450, family
4, subfamily A, polypeptide 22 protein.
Length = 421
Score = 67.3 bits (157), Expect = 7e-11
Identities = 40/127 (31%), Positives = 67/127 (52%), Gaps = 4/127 (3%)
Frame = +2
Query: 356 SVVKIWI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSH 532
S WI G ++ V LYDP ++VIL Y+F P +G GLL+ GQ W H
Sbjct: 84 SACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YKFLAPRIGYGLLLLNGQTWFQH 142
Query: 533 RKLIAPTFHLNVLKSFIELFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAM 703
R+++ P FH ++LK ++ L + R ++DK L + S + ++S T++ ++++A
Sbjct: 143 RRMLTPAFHNDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKSAF 202
Query: 704 GVSKSTQ 724
S Q
Sbjct: 203 SHQGSIQ 209
>AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P450
4B1 variant protein.
Length = 497
Score = 62.9 bits (146), Expect = 1e-09
Identities = 35/136 (25%), Positives = 63/136 (46%), Gaps = 4/136 (2%)
Frame = +2
Query: 488 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIELFNANSRAVVDKLK---KEASNFDCHD 658
G GLL+ G KW HRKL+ P FH +VLK ++ +F ++R ++DK + +E +FD
Sbjct: 108 GRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFC 167
Query: 659 YMSECTVEILLETAMGVSKSTQDQS-GFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTD 835
+ + L++ G + S Y +AV + ++ R D ++ T
Sbjct: 168 DVGHMALNTLMKCTFGRGDTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTP 227
Query: 836 YAKNQTKLLDIIHGLT 883
+ + + + H T
Sbjct: 228 HGRRFLRACQVAHDHT 243
>AL593856-5|CAI16983.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 62.9 bits (146), Expect = 1e-09
Identities = 35/136 (25%), Positives = 63/136 (46%), Gaps = 4/136 (2%)
Frame = +2
Query: 488 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIELFNANSRAVVDKLK---KEASNFDCHD 658
G GLL+ G KW HRKL+ P FH +VLK ++ +F ++R ++DK + +E +FD
Sbjct: 108 GRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFC 167
Query: 659 YMSECTVEILLETAMGVSKSTQDQS-GFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTD 835
+ + L++ G + S Y +AV + ++ R D ++ T
Sbjct: 168 DVGHMALNTLMKCTFGRGDTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTP 227
Query: 836 YAKNQTKLLDIIHGLT 883
+ + + + H T
Sbjct: 228 HGRRFLRACQVAHDHT 243
>AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 62.9 bits (146), Expect = 1e-09
Identities = 35/136 (25%), Positives = 63/136 (46%), Gaps = 4/136 (2%)
Frame = +2
Query: 488 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIELFNANSRAVVDKLK---KEASNFDCHD 658
G GLL+ G KW HRKL+ P FH +VLK ++ +F ++R ++DK + +E +FD
Sbjct: 108 GRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFC 167
Query: 659 YMSECTVEILLETAMGVSKSTQDQS-GFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTD 835
+ + L++ G + S Y +AV + ++ R D ++ T
Sbjct: 168 DVGHMALNTLMKCTFGRGDTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTP 227
Query: 836 YAKNQTKLLDIIHGLT 883
+ + + + H T
Sbjct: 228 HGRRFLRACQVAHDHT 243
>X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (cyp3 locus). ).
Length = 503
Score = 39.5 bits (88), Expect = 0.016
Identities = 28/129 (21%), Positives = 59/129 (45%), Gaps = 8/129 (6%)
Frame = +2
Query: 350 HESVVKIW---IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTG 514
H+ K+W G + ++ + DP ++ +L Y R F P ++ + + I+
Sbjct: 65 HKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAED 123
Query: 515 QKWRSHRKLIAPTFHLNVLKSFIELFNANSRAVVDKLKKEASN---FDCHDYMSECTVEI 685
++W+ R L++PTF LK + + +V L++EA D ++++
Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183
Query: 686 LLETAMGVS 712
+ T+ GV+
Sbjct: 184 ITSTSFGVN 192
>M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA
encoding nifedipine oxidase, complete cds. ).
Length = 503
Score = 39.5 bits (88), Expect = 0.016
Identities = 28/129 (21%), Positives = 59/129 (45%), Gaps = 8/129 (6%)
Frame = +2
Query: 350 HESVVKIW---IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTG 514
H+ K+W G + ++ + DP ++ +L Y R F P ++ + + I+
Sbjct: 65 HKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAED 123
Query: 515 QKWRSHRKLIAPTFHLNVLKSFIELFNANSRAVVDKLKKEASN---FDCHDYMSECTVEI 685
++W+ R L++PTF LK + + +V L++EA D ++++
Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183
Query: 686 LLETAMGVS 712
+ T+ GV+
Sbjct: 184 ITSTSFGVN 192
>M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrome
P-450 nifedipine oxidase mRNA, complet cds. ).
Length = 503
Score = 39.5 bits (88), Expect = 0.016
Identities = 28/129 (21%), Positives = 59/129 (45%), Gaps = 8/129 (6%)
Frame = +2
Query: 350 HESVVKIW---IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTG 514
H+ K+W G + ++ + DP ++ +L Y R F P ++ + + I+
Sbjct: 65 HKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAED 123
Query: 515 QKWRSHRKLIAPTFHLNVLKSFIELFNANSRAVVDKLKKEASN---FDCHDYMSECTVEI 685
++W+ R L++PTF LK + + +V L++EA D ++++
Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183
Query: 686 LLETAMGVS 712
+ T+ GV+
Sbjct: 184 ITSTSFGVN 192
>DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family 3
subfamily A polypeptide 4 protein.
Length = 503
Score = 39.5 bits (88), Expect = 0.016
Identities = 28/129 (21%), Positives = 59/129 (45%), Gaps = 8/129 (6%)
Frame = +2
Query: 350 HESVVKIW---IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTG 514
H+ K+W G + ++ + DP ++ +L Y R F P ++ + + I+
Sbjct: 65 HKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAED 123
Query: 515 QKWRSHRKLIAPTFHLNVLKSFIELFNANSRAVVDKLKKEASN---FDCHDYMSECTVEI 685
++W+ R L++PTF LK + + +V L++EA D ++++
Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183
Query: 686 LLETAMGVS 712
+ T+ GV+
Sbjct: 184 ITSTSFGVN 192
>DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 39.5 bits (88), Expect = 0.016
Identities = 28/129 (21%), Positives = 59/129 (45%), Gaps = 8/129 (6%)
Frame = +2
Query: 350 HESVVKIW---IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTG 514
H+ K+W G + ++ + DP ++ +L Y R F P ++ + + I+
Sbjct: 65 HKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAED 123
Query: 515 QKWRSHRKLIAPTFHLNVLKSFIELFNANSRAVVDKLKKEASN---FDCHDYMSECTVEI 685
++W+ R L++PTF LK + + +V L++EA D ++++
Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183
Query: 686 LLETAMGVS 712
+ T+ GV+
Sbjct: 184 ITSTSFGVN 192
>BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfamily
IIIA, polypeptide 4 protein.
Length = 503
Score = 39.5 bits (88), Expect = 0.016
Identities = 28/129 (21%), Positives = 59/129 (45%), Gaps = 8/129 (6%)
Frame = +2
Query: 350 HESVVKIW---IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTG 514
H+ K+W G + ++ + DP ++ +L Y R F P ++ + + I+
Sbjct: 65 HKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAED 123
Query: 515 QKWRSHRKLIAPTFHLNVLKSFIELFNANSRAVVDKLKKEASN---FDCHDYMSECTVEI 685
++W+ R L++PTF LK + + +V L++EA D ++++
Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183
Query: 686 LLETAMGVS 712
+ T+ GV+
Sbjct: 184 ITSTSFGVN 192
>BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 39.5 bits (88), Expect = 0.016
Identities = 28/129 (21%), Positives = 59/129 (45%), Gaps = 8/129 (6%)
Frame = +2
Query: 350 HESVVKIW---IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTG 514
H+ K+W G + ++ + DP ++ +L Y R F P ++ + + I+
Sbjct: 65 HKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAED 123
Query: 515 QKWRSHRKLIAPTFHLNVLKSFIELFNANSRAVVDKLKKEASN---FDCHDYMSECTVEI 685
++W+ R L++PTF LK + + +V L++EA D ++++
Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183
Query: 686 LLETAMGVS 712
+ T+ GV+
Sbjct: 184 ITSTSFGVN 192
>AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein.
Length = 503
Score = 39.5 bits (88), Expect = 0.016
Identities = 28/129 (21%), Positives = 59/129 (45%), Gaps = 8/129 (6%)
Frame = +2
Query: 350 HESVVKIW---IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTG 514
H+ K+W G + ++ + DP ++ +L Y R F P ++ + + I+
Sbjct: 65 HKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAED 123
Query: 515 QKWRSHRKLIAPTFHLNVLKSFIELFNANSRAVVDKLKKEASN---FDCHDYMSECTVEI 685
++W+ R L++PTF LK + + +V L++EA D ++++
Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183
Query: 686 LLETAMGVS 712
+ T+ GV+
Sbjct: 184 ITSTSFGVN 192
>AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450
polypeptide 4 protein.
Length = 503
Score = 39.5 bits (88), Expect = 0.016
Identities = 28/129 (21%), Positives = 59/129 (45%), Gaps = 8/129 (6%)
Frame = +2
Query: 350 HESVVKIW---IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTG 514
H+ K+W G + ++ + DP ++ +L Y R F P ++ + + I+
Sbjct: 65 HKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAED 123
Query: 515 QKWRSHRKLIAPTFHLNVLKSFIELFNANSRAVVDKLKKEASN---FDCHDYMSECTVEI 685
++W+ R L++PTF LK + + +V L++EA D ++++
Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183
Query: 686 LLETAMGVS 712
+ T+ GV+
Sbjct: 184 ITSTSFGVN 192
>AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4
protein.
Length = 503
Score = 39.5 bits (88), Expect = 0.016
Identities = 28/129 (21%), Positives = 59/129 (45%), Gaps = 8/129 (6%)
Frame = +2
Query: 350 HESVVKIW---IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTG 514
H+ K+W G + ++ + DP ++ +L Y R F P ++ + + I+
Sbjct: 65 HKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAED 123
Query: 515 QKWRSHRKLIAPTFHLNVLKSFIELFNANSRAVVDKLKKEASN---FDCHDYMSECTVEI 685
++W+ R L++PTF LK + + +V L++EA D ++++
Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183
Query: 686 LLETAMGVS 712
+ T+ GV+
Sbjct: 184 ITSTSFGVN 192
>AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4
protein.
Length = 503
Score = 39.5 bits (88), Expect = 0.016
Identities = 28/129 (21%), Positives = 59/129 (45%), Gaps = 8/129 (6%)
Frame = +2
Query: 350 HESVVKIW---IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTG 514
H+ K+W G + ++ + DP ++ +L Y R F P ++ + + I+
Sbjct: 65 HKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAED 123
Query: 515 QKWRSHRKLIAPTFHLNVLKSFIELFNANSRAVVDKLKKEASN---FDCHDYMSECTVEI 685
++W+ R L++PTF LK + + +V L++EA D ++++
Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183
Query: 686 LLETAMGVS 712
+ T+ GV+
Sbjct: 184 ITSTSFGVN 192
>J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipine
oxidase protein.
Length = 502
Score = 37.1 bits (82), Expect = 0.085
Identities = 25/117 (21%), Positives = 54/117 (46%), Gaps = 5/117 (4%)
Frame = +2
Query: 377 GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTGQKWRSHRKLIAP 550
G + ++ + DP ++ +L Y R F P ++ + + I+ ++W+ R L++P
Sbjct: 77 GQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSP 135
Query: 551 TFHLNVLKSFIELFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 712
TF LK + + +V L++EA D +++++ T+ GV+
Sbjct: 136 TFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVN 192
>AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein.
Length = 430
Score = 37.1 bits (82), Expect = 0.085
Identities = 25/117 (21%), Positives = 54/117 (46%), Gaps = 5/117 (4%)
Frame = +2
Query: 377 GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTGQKWRSHRKLIAP 550
G + ++ + DP ++ +L Y R F P ++ + + I+ ++W+ R L++P
Sbjct: 4 GQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSP 62
Query: 551 TFHLNVLKSFIELFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 712
TF LK + + +V L++EA D +++++ T+ GV+
Sbjct: 63 TFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVN 119
>D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa
protein.
Length = 503
Score = 36.7 bits (81), Expect = 0.11
Identities = 25/113 (22%), Positives = 51/113 (45%), Gaps = 5/113 (4%)
Frame = +2
Query: 389 LVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTGQKWRSHRKLIAPTFHL 562
++ + DP ++ +L Y R F P ++ N + I+ ++W+ R L++PTF
Sbjct: 81 MLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKNAISIAEDEEWKRIRSLLSPTFTS 139
Query: 563 NVLKSFIELFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 712
LK + + +V L++EA +++++ T+ GVS
Sbjct: 140 GKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVITSTSFGVS 192
>BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 7 protein.
Length = 503
Score = 36.7 bits (81), Expect = 0.11
Identities = 25/113 (22%), Positives = 51/113 (45%), Gaps = 5/113 (4%)
Frame = +2
Query: 389 LVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTGQKWRSHRKLIAPTFHL 562
++ + DP ++ +L Y R F P ++ N + I+ ++W+ R L++PTF
Sbjct: 81 MLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKNAISIAEDEEWKRIRSLLSPTFTS 139
Query: 563 NVLKSFIELFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 712
LK + + +V L++EA +++++ T+ GVS
Sbjct: 140 GKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVITSTSFGVS 192
>AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant
3A7 protein.
Length = 535
Score = 36.7 bits (81), Expect = 0.11
Identities = 25/113 (22%), Positives = 51/113 (45%), Gaps = 5/113 (4%)
Frame = +2
Query: 389 LVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTGQKWRSHRKLIAPTFHL 562
++ + DP ++ +L Y R F P ++ N + I+ ++W+ R L++PTF
Sbjct: 81 MLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKNAISIAEDEEWKRIRSLLSPTFTS 139
Query: 563 NVLKSFIELFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 712
LK + + +V L++EA +++++ T+ GVS
Sbjct: 140 GKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVITSTSFGVS 192
>AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450
polypeptide 7 protein.
Length = 503
Score = 36.7 bits (81), Expect = 0.11
Identities = 25/113 (22%), Positives = 51/113 (45%), Gaps = 5/113 (4%)
Frame = +2
Query: 389 LVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTGQKWRSHRKLIAPTFHL 562
++ + DP ++ +L Y R F P ++ N + I+ ++W+ R L++PTF
Sbjct: 81 MLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKNAISIAEDEEWKRIRSLLSPTFTS 139
Query: 563 NVLKSFIELFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 712
LK + + +V L++EA +++++ T+ GVS
Sbjct: 140 GKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVITSTSFGVS 192
>J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein.
Length = 491
Score = 35.9 bits (79), Expect = 0.20
Identities = 34/140 (24%), Positives = 59/140 (42%), Gaps = 5/140 (3%)
Frame = +2
Query: 302 SADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVIL--SSHVYIDKAEEYRFF 475
S D+ ++ + S +Y S+ + +GPR +V L + V+ L + + + FF
Sbjct: 48 SQDMLTSLTKLSKEYG--SMYTVHLGPRRVVVLSGYQAVKEALVDQGEEFSGRGDYPAFF 105
Query: 476 KPWLGNGLLISTGQKWRSHRKL-IAPTFHLNVLKSFIE--LFNANSRAVVDKLKKEASNF 646
GNG+ S+G +W+ R+ I + + K IE + S + D K E F
Sbjct: 106 NFTKGNGIAFSSGDRWKVLRQFSIQILRNFGMGKRSIEERILEEGSFLLADVRKTEGEPF 165
Query: 647 DCHDYMSECTVEILLETAMG 706
D +S I+ G
Sbjct: 166 DPTFVLSRSVSNIICSVLFG 185
>AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43.1
protein.
Length = 503
Score = 35.9 bits (79), Expect = 0.20
Identities = 23/119 (19%), Positives = 54/119 (45%), Gaps = 4/119 (3%)
Frame = +2
Query: 368 IWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP-WLGNGLLISTGQKWRSHRKLI 544
++ G + ++ + DP ++ +L Y + +L + L + ++W+ R L+
Sbjct: 74 LYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEWKRIRTLL 133
Query: 545 APTFHLNVLKSFIELFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 712
+P F K + + + +V L++EA N + D+ T++++ T GV+
Sbjct: 134 SPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVN 192
>AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43.3
protein.
Length = 503
Score = 35.9 bits (79), Expect = 0.20
Identities = 23/119 (19%), Positives = 54/119 (45%), Gaps = 4/119 (3%)
Frame = +2
Query: 368 IWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP-WLGNGLLISTGQKWRSHRKLI 544
++ G + ++ + DP ++ +L Y + +L + L + ++W+ R L+
Sbjct: 74 LYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEWKRIRTLL 133
Query: 545 APTFHLNVLKSFIELFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 712
+P F K + + + +V L++EA N + D+ T++++ T GV+
Sbjct: 134 SPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVN 192
>AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 35.9 bits (79), Expect = 0.20
Identities = 23/119 (19%), Positives = 54/119 (45%), Gaps = 4/119 (3%)
Frame = +2
Query: 368 IWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP-WLGNGLLISTGQKWRSHRKLI 544
++ G + ++ + DP ++ +L Y + +L + L + ++W+ R L+
Sbjct: 74 LYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEWKRIRTLL 133
Query: 545 APTFHLNVLKSFIELFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 712
+P F K + + + +V L++EA N + D+ T++++ T GV+
Sbjct: 134 SPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVN 192
>AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43
protein.
Length = 503
Score = 35.9 bits (79), Expect = 0.20
Identities = 23/119 (19%), Positives = 54/119 (45%), Gaps = 4/119 (3%)
Frame = +2
Query: 368 IWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP-WLGNGLLISTGQKWRSHRKLI 544
++ G + ++ + DP ++ +L Y + +L + L + ++W+ R L+
Sbjct: 74 LYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEWKRIRTLL 133
Query: 545 APTFHLNVLKSFIELFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 712
+P F K + + + +V L++EA N + D+ T++++ T GV+
Sbjct: 134 SPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVN 192
>AF280111-1|AAG33012.1| 250|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 250
Score = 35.9 bits (79), Expect = 0.20
Identities = 23/119 (19%), Positives = 54/119 (45%), Gaps = 4/119 (3%)
Frame = +2
Query: 368 IWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP-WLGNGLLISTGQKWRSHRKLI 544
++ G + ++ + DP ++ +L Y + +L + L + ++W+ R L+
Sbjct: 74 LYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEWKRIRTLL 133
Query: 545 APTFHLNVLKSFIELFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 712
+P F K + + + +V L++EA N + D+ T++++ T GV+
Sbjct: 134 SPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVN 192
>AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 420
Score = 35.9 bits (79), Expect = 0.20
Identities = 23/119 (19%), Positives = 54/119 (45%), Gaps = 4/119 (3%)
Frame = +2
Query: 368 IWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP-WLGNGLLISTGQKWRSHRKLI 544
++ G + ++ + DP ++ +L Y + +L + L + ++W+ R L+
Sbjct: 74 LYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEWKRIRTLL 133
Query: 545 APTFHLNVLKSFIELFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 712
+P F K + + + +V L++EA N + D+ T++++ T GV+
Sbjct: 134 SPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVN 192
>AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 504
Score = 35.9 bits (79), Expect = 0.20
Identities = 23/119 (19%), Positives = 54/119 (45%), Gaps = 4/119 (3%)
Frame = +2
Query: 368 IWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP-WLGNGLLISTGQKWRSHRKLI 544
++ G + ++ + DP ++ +L Y + +L + L + ++W+ R L+
Sbjct: 74 LYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEWKRIRTLL 133
Query: 545 APTFHLNVLKSFIELFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 712
+P F K + + + +V L++EA N + D+ T++++ T GV+
Sbjct: 134 SPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVN 192
>AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 35.9 bits (79), Expect = 0.20
Identities = 23/119 (19%), Positives = 54/119 (45%), Gaps = 4/119 (3%)
Frame = +2
Query: 368 IWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP-WLGNGLLISTGQKWRSHRKLI 544
++ G + ++ + DP ++ +L Y + +L + L + ++W+ R L+
Sbjct: 74 LYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEWKRIRTLL 133
Query: 545 APTFHLNVLKSFIELFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 712
+P F K + + + +V L++EA N + D+ T++++ T GV+
Sbjct: 134 SPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVN 192
>AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein.
Length = 504
Score = 35.9 bits (79), Expect = 0.20
Identities = 23/119 (19%), Positives = 54/119 (45%), Gaps = 4/119 (3%)
Frame = +2
Query: 368 IWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP-WLGNGLLISTGQKWRSHRKLI 544
++ G + ++ + DP ++ +L Y + +L + L + ++W+ R L+
Sbjct: 74 LYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEWKRIRTLL 133
Query: 545 APTFHLNVLKSFIELFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 712
+P F K + + + +V L++EA N + D+ T++++ T GV+
Sbjct: 134 SPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVN 192
>AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein.
Length = 503
Score = 35.9 bits (79), Expect = 0.20
Identities = 23/119 (19%), Positives = 54/119 (45%), Gaps = 4/119 (3%)
Frame = +2
Query: 368 IWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP-WLGNGLLISTGQKWRSHRKLI 544
++ G + ++ + DP ++ +L Y + +L + L + ++W+ R L+
Sbjct: 74 LYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEWKRIRTLL 133
Query: 545 APTFHLNVLKSFIELFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 712
+P F K + + + +V L++EA N + D+ T++++ T GV+
Sbjct: 134 SPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVN 192
>EF122242-1|ABO41977.1| 321|Homo sapiens cytochrome P450 2F1
variant protein.
Length = 321
Score = 35.5 bits (78), Expect = 0.26
Identities = 27/115 (23%), Positives = 56/115 (48%), Gaps = 2/115 (1%)
Frame = +2
Query: 302 SADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVIL--SSHVYIDKAEEYRFF 475
S D+ ++ + S +Y S+ + +GPR +V L + V+ L + + + FF
Sbjct: 48 SQDMLTSLTKLSKEYG--SMYTVHLGPRRVVVLSGYQAVKEALVDQGEEFSGRGDYPAFF 105
Query: 476 KPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIELFNANSRAVVDKLKKEAS 640
GNG+ S+G +W+ R+ F + +L++ F R++ +++ +E S
Sbjct: 106 NFTKGNGIAFSSGDRWKVLRQ-----FSIQILRN----FGMGKRSIEERILEEGS 151
>EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1
variant protein.
Length = 491
Score = 35.5 bits (78), Expect = 0.26
Identities = 27/115 (23%), Positives = 56/115 (48%), Gaps = 2/115 (1%)
Frame = +2
Query: 302 SADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVIL--SSHVYIDKAEEYRFF 475
S D+ ++ + S +Y S+ + +GPR +V L + V+ L + + + FF
Sbjct: 48 SQDMLTSLTKLSKEYG--SMYTVHLGPRRVVVLSGYQAVKEALVDQGEEFSGRGDYPAFF 105
Query: 476 KPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIELFNANSRAVVDKLKKEAS 640
GNG+ S+G +W+ R+ F + +L++ F R++ +++ +E S
Sbjct: 106 NFTKGNGIAFSSGDRWKVLRQ-----FSIQILRN----FGMGKRSIEERILEEGS 151
>BC109056-1|AAI09057.1| 320|Homo sapiens CYP2F1 protein protein.
Length = 320
Score = 35.5 bits (78), Expect = 0.26
Identities = 27/115 (23%), Positives = 56/115 (48%), Gaps = 2/115 (1%)
Frame = +2
Query: 302 SADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVIL--SSHVYIDKAEEYRFF 475
S D+ ++ + S +Y S+ + +GPR +V L + V+ L + + + FF
Sbjct: 48 SQDMLTSLTKLSKEYG--SMYTVHLGPRRVVVLSGYQAVKEALVDQGEEFSGRGDYPAFF 105
Query: 476 KPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIELFNANSRAVVDKLKKEAS 640
GNG+ S+G +W+ R+ F + +L++ F R++ +++ +E S
Sbjct: 106 NFTKGNGIAFSSGDRWKVLRQ-----FSIQILRN----FGMGKRSIEERILEEGS 151
>AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1
protein.
Length = 495
Score = 35.5 bits (78), Expect = 0.26
Identities = 27/115 (23%), Positives = 56/115 (48%), Gaps = 2/115 (1%)
Frame = +2
Query: 302 SADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVIL--SSHVYIDKAEEYRFF 475
S D+ ++ + S +Y S+ + +GPR +V L + V+ L + + + FF
Sbjct: 48 SQDMLTSLTKLSKEYG--SMYTVHLGPRRVVVLSGYQAVKEALVDQGEEFSGRGDYPAFF 105
Query: 476 KPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIELFNANSRAVVDKLKKEAS 640
GNG+ S+G +W+ R+ F + +L++ F R++ +++ +E S
Sbjct: 106 NFTKGNGIAFSSGDRWKVLRQ-----FSIQILRN----FGMGKRSIEERILEEGS 151
>M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver
glucocorticoid-inducible cytochrome P-450 (HLp) mRNA,
complete cds. ).
Length = 504
Score = 34.7 bits (76), Expect = 0.45
Identities = 24/128 (18%), Positives = 57/128 (44%), Gaps = 7/128 (5%)
Frame = +2
Query: 350 HESVVKIW---IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP-WLGNGLLISTGQ 517
H+ K+W G + ++ + DP ++++L Y F ++ + + I+ +
Sbjct: 65 HKKYGKVWGFYDGQQPVLAITDPDMIKLVLVKECYSVFTNREPFGPVGFMKSAISIAEDE 124
Query: 518 KWRSHRKLIAPTFHLNVLKSFIELFNANSRAVVDKLKKEASN---FDCHDYMSECTVEIL 688
+W+ R L++PTF LK + + +V L++E D +++++
Sbjct: 125 EWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRRERETGKPVTLKDVFGAYSMDVI 184
Query: 689 LETAMGVS 712
++ GV+
Sbjct: 185 TSSSFGVN 192
>D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein.
Length = 504
Score = 34.7 bits (76), Expect = 0.45
Identities = 24/128 (18%), Positives = 57/128 (44%), Gaps = 7/128 (5%)
Frame = +2
Query: 350 HESVVKIW---IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP-WLGNGLLISTGQ 517
H+ K+W G + ++ + DP ++++L Y F ++ + + I+ +
Sbjct: 65 HKKYGKVWGFYDGQQPVLAITDPDMIKLVLVKECYSVFTNREPFGPVGFMKSAISIAEDE 124
Query: 518 KWRSHRKLIAPTFHLNVLKSFIELFNANSRAVVDKLKKEASN---FDCHDYMSECTVEIL 688
+W+ R L++PTF LK + + +V L++E D +++++
Sbjct: 125 EWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRRERETGKPVTLKDVFGAYSMDVI 184
Query: 689 LETAMGVS 712
++ GV+
Sbjct: 185 TSSSFGVN 192
>U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450
monooxygenase CYP2J2 protein.
Length = 502
Score = 31.9 bits (69), Expect = 3.2
Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 3/93 (3%)
Frame = +2
Query: 491 NGLLISTGQKWRSHRKLIAPTFHLNVL--KSFIELFNANSRAVVDKLKKE-ASNFDCHDY 661
NGL++S+GQ W+ R+ L KS E ++ + + +K+E FD H
Sbjct: 124 NGLIMSSGQAWKEQRRFTLTALRNFGLGKKSLEERIQEEAQHLTEAIKEENGQPFDPHFK 183
Query: 662 MSECTVEILLETAMGVSKSTQDQSGFEYAMAVM 760
++ I+ G QD S F+ + ++
Sbjct: 184 INNAVSNIICSITFGERFEYQD-SWFQQLLKLL 215
>BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 31.9 bits (69), Expect = 3.2
Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 3/93 (3%)
Frame = +2
Query: 491 NGLLISTGQKWRSHRKLIAPTFHLNVL--KSFIELFNANSRAVVDKLKKE-ASNFDCHDY 661
NGL++S+GQ W+ R+ L KS E ++ + + +K+E FD H
Sbjct: 124 NGLIMSSGQAWKEQRRFTLTALRNFGLGKKSLEERIQEEAQHLTEAIKEENGQPFDPHFK 183
Query: 662 MSECTVEILLETAMGVSKSTQDQSGFEYAMAVM 760
++ I+ G QD S F+ + ++
Sbjct: 184 INNAVSNIICSITFGERFEYQD-SWFQQLLKLL 215
>AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 31.9 bits (69), Expect = 3.2
Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 3/93 (3%)
Frame = +2
Query: 491 NGLLISTGQKWRSHRKLIAPTFHLNVL--KSFIELFNANSRAVVDKLKKE-ASNFDCHDY 661
NGL++S+GQ W+ R+ L KS E ++ + + +K+E FD H
Sbjct: 124 NGLIMSSGQAWKEQRRFTLTALRNFGLGKKSLEERIQEEAQHLTEAIKEENGQPFDPHFK 183
Query: 662 MSECTVEILLETAMGVSKSTQDQSGFEYAMAVM 760
++ I+ G QD S F+ + ++
Sbjct: 184 INNAVSNIICSITFGERFEYQD-SWFQQLLKLL 215
>AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein.
Length = 502
Score = 31.9 bits (69), Expect = 3.2
Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 3/93 (3%)
Frame = +2
Query: 491 NGLLISTGQKWRSHRKLIAPTFHLNVL--KSFIELFNANSRAVVDKLKKE-ASNFDCHDY 661
NGL++S+GQ W+ R+ L KS E ++ + + +K+E FD H
Sbjct: 124 NGLIMSSGQAWKEQRRFTLTALRNFGLGKKSLEERIQEEAQHLTEAIKEENGQPFDPHFK 183
Query: 662 MSECTVEILLETAMGVSKSTQDQSGFEYAMAVM 760
++ I+ G QD S F+ + ++
Sbjct: 184 INNAVSNIICSITFGERFEYQD-SWFQQLLKLL 215
>AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2
protein.
Length = 502
Score = 31.9 bits (69), Expect = 3.2
Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 3/93 (3%)
Frame = +2
Query: 491 NGLLISTGQKWRSHRKLIAPTFHLNVL--KSFIELFNANSRAVVDKLKKE-ASNFDCHDY 661
NGL++S+GQ W+ R+ L KS E ++ + + +K+E FD H
Sbjct: 124 NGLIMSSGQAWKEQRRFTLTALRNFGLGKKSLEERIQEEAQHLTEAIKEENGQPFDPHFK 183
Query: 662 MSECTVEILLETAMGVSKSTQDQSGFEYAMAVM 760
++ I+ G QD S F+ + ++
Sbjct: 184 INNAVSNIICSITFGERFEYQD-SWFQQLLKLL 215
>J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3
protein.
Length = 502
Score = 31.5 bits (68), Expect = 4.2
Identities = 16/80 (20%), Positives = 38/80 (47%), Gaps = 3/80 (3%)
Frame = +2
Query: 482 WLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIELFNANSRAVVDKLKKEASN---FDC 652
++ + + ++ ++W+ R L++PTF LK + +V L++EA
Sbjct: 113 FMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTL 172
Query: 653 HDYMSECTVEILLETAMGVS 712
D +++++ T+ GV+
Sbjct: 173 KDIFGAYSMDVITGTSFGVN 192
>DQ680079-1|ABG25922.1| 347|Homo sapiens truncated cytochrome P450,
family 3, subfamily A, polypeptide 5 protein.
Length = 347
Score = 31.5 bits (68), Expect = 4.2
Identities = 16/80 (20%), Positives = 38/80 (47%), Gaps = 3/80 (3%)
Frame = +2
Query: 482 WLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIELFNANSRAVVDKLKKEASN---FDC 652
++ + + ++ ++W+ R L++PTF LK + +V L++EA
Sbjct: 113 FMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTL 172
Query: 653 HDYMSECTVEILLETAMGVS 712
D +++++ T+ GV+
Sbjct: 173 KDIFGAYSMDVITGTSFGVN 192
>BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 protein.
Length = 502
Score = 31.5 bits (68), Expect = 4.2
Identities = 16/80 (20%), Positives = 38/80 (47%), Gaps = 3/80 (3%)
Frame = +2
Query: 482 WLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIELFNANSRAVVDKLKKEASN---FDC 652
++ + + ++ ++W+ R L++PTF LK + +V L++EA
Sbjct: 113 FMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTL 172
Query: 653 HDYMSECTVEILLETAMGVS 712
D +++++ T+ GV+
Sbjct: 173 KDIFGAYSMDVITGTSFGVN 192
>AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein.
Length = 502
Score = 31.5 bits (68), Expect = 4.2
Identities = 16/80 (20%), Positives = 38/80 (47%), Gaps = 3/80 (3%)
Frame = +2
Query: 482 WLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIELFNANSRAVVDKLKKEASN---FDC 652
++ + + ++ ++W+ R L++PTF LK + +V L++EA
Sbjct: 113 FMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTL 172
Query: 653 HDYMSECTVEILLETAMGVS 712
D +++++ T+ GV+
Sbjct: 173 KDIFGAYSMDVITGTSFGVN 192
>AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 variant protein.
Length = 502
Score = 31.1 bits (67), Expect = 5.6
Identities = 16/80 (20%), Positives = 38/80 (47%), Gaps = 3/80 (3%)
Frame = +2
Query: 482 WLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIELFNANSRAVVDKLKKEASN---FDC 652
++ + + ++ ++W+ R L++PTF LK + +V L++EA
Sbjct: 113 FMKSAISLAEDEEWKRIRPLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTL 172
Query: 653 HDYMSECTVEILLETAMGVS 712
D +++++ T+ GV+
Sbjct: 173 KDIFGAYSMDVITGTSFGVN 192
>BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family 2,
subfamily S, polypeptide 1 protein.
Length = 504
Score = 30.7 bits (66), Expect = 7.3
Identities = 22/84 (26%), Positives = 39/84 (46%), Gaps = 3/84 (3%)
Frame = +2
Query: 488 GNGLLISTGQKWRSHRKLIAPTFH-LNVLK-SFIELFNANSRAVVDKLK-KEASNFDCHD 658
G+G+ S G++WR RK L + K EL A +R +V+ + E FD
Sbjct: 113 GHGVFFSNGERWRQLRKFTMLALRDLGMGKREGEELIQAEARCLVETFQGTEGRPFDPSL 172
Query: 659 YMSECTVEILLETAMGVSKSTQDQ 730
+++ T ++ G+ S +D+
Sbjct: 173 LLAQATSNVVCSLLFGLRFSYEDK 196
>AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein.
Length = 504
Score = 30.7 bits (66), Expect = 7.3
Identities = 22/84 (26%), Positives = 39/84 (46%), Gaps = 3/84 (3%)
Frame = +2
Query: 488 GNGLLISTGQKWRSHRKLIAPTFH-LNVLK-SFIELFNANSRAVVDKLK-KEASNFDCHD 658
G+G+ S G++WR RK L + K EL A +R +V+ + E FD
Sbjct: 113 GHGVFFSNGERWRQLRKFTMLALRDLGMGKREGEELIQAEARCLVETFQGTEGRPFDPSL 172
Query: 659 YMSECTVEILLETAMGVSKSTQDQ 730
+++ T ++ G+ S +D+
Sbjct: 173 LLAQATSNVVCSLLFGLRFSYEDK 196
>AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens
cDNA FLJ14699 fis, clone NT2RP2006571, moderately
similar to CYTOCHROME P450 2G1 (EC 1.14.14.1). ).
Length = 564
Score = 30.7 bits (66), Expect = 7.3
Identities = 22/84 (26%), Positives = 39/84 (46%), Gaps = 3/84 (3%)
Frame = +2
Query: 488 GNGLLISTGQKWRSHRKLIAPTFH-LNVLK-SFIELFNANSRAVVDKLK-KEASNFDCHD 658
G+G+ S G++WR RK L + K EL A +R +V+ + E FD
Sbjct: 113 GHGVFFSNGERWRQLRKFTMLALRDLGMGKREGEELIQAEARCLVETFQGTEGRPFDPSL 172
Query: 659 YMSECTVEILLETAMGVSKSTQDQ 730
+++ T ++ G+ S +D+
Sbjct: 173 LLAQATSNVVCSLLFGLRFSYEDK 196
>AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1
protein.
Length = 504
Score = 30.7 bits (66), Expect = 7.3
Identities = 22/84 (26%), Positives = 39/84 (46%), Gaps = 3/84 (3%)
Frame = +2
Query: 488 GNGLLISTGQKWRSHRKLIAPTFH-LNVLK-SFIELFNANSRAVVDKLK-KEASNFDCHD 658
G+G+ S G++WR RK L + K EL A +R +V+ + E FD
Sbjct: 113 GHGVFFSNGERWRQLRKFTMLALRDLGMGKREGEELIQAEARCLVETFQGTEGRPFDPSL 172
Query: 659 YMSECTVEILLETAMGVSKSTQDQ 730
+++ T ++ G+ S +D+
Sbjct: 173 LLAQATSNVVCSLLFGLRFSYEDK 196
>AF144566-1|AAD30164.1| 339|Homo sapiens cytochrome P450
epoxygenase protein.
Length = 339
Score = 30.3 bits (65), Expect = 9.7
Identities = 22/93 (23%), Positives = 40/93 (43%), Gaps = 3/93 (3%)
Frame = +2
Query: 491 NGLLISTGQKWRSHRKLIAPTFHLNVL--KSFIELFNANSRAVVDKLKKE-ASNFDCHDY 661
NGL++S+GQ W+ R+ L K E ++ + + +K+E FD H
Sbjct: 93 NGLIMSSGQAWKEQRRFTLTALRNFGLGKKGLEERIQEEAQHLTEAIKEENGQPFDPHFK 152
Query: 662 MSECTVEILLETAMGVSKSTQDQSGFEYAMAVM 760
++ I+ G QD S F+ + ++
Sbjct: 153 INNAVSNIICSITFGERFEYQD-SWFQQLLKLL 184
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 124,967,894
Number of Sequences: 237096
Number of extensions: 2719559
Number of successful extensions: 6183
Number of sequences better than 10.0: 129
Number of HSP's better than 10.0 without gapping: 5752
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6172
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11326166088
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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