Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P08_F_F19
(773 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein. 193 7e-49
J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein. 192 9e-49
X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for ... 192 2e-48
M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein. 192 2e-48
M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose re... 192 2e-48
J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein. 192 2e-48
J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein. 192 2e-48
BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase fam... 192 2e-48
BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase fam... 192 2e-48
BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase fam... 192 2e-48
AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen HD-C... 192 2e-48
AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein. 192 2e-48
AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase fam... 192 2e-48
CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein. 191 2e-48
BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase fam... 186 8e-47
J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein. 184 4e-46
CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein. 184 4e-46
BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase fam... 184 4e-46
BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase fam... 184 4e-46
BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase fam... 184 4e-46
AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase fam... 184 4e-46
AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase prot... 184 4e-46
AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase prot... 184 4e-46
S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase hom... 182 1e-45
L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol dehydrogenase... 182 1e-45
U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase... 180 4e-45
BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase fam... 180 4e-45
BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase fam... 180 4e-45
BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase fam... 180 4e-45
AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase fam... 180 4e-45
AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase fam... 180 4e-45
AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase fam... 180 4e-45
AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding prote... 180 4e-45
AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding prote... 180 4e-45
AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding p... 180 4e-45
U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol dehyd... 179 9e-45
U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase... 179 9e-45
M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase... 179 9e-45
BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase fam... 179 9e-45
BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase fam... 179 9e-45
BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase fam... 179 9e-45
BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase fam... 179 9e-45
AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase fam... 179 9e-45
AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid ... 179 9e-45
AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid... 179 9e-45
U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like pep... 176 6e-44
CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein. 176 6e-44
BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase fam... 176 6e-44
BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase fam... 176 6e-44
AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase pro... 176 6e-44
DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxystero... 175 2e-43
AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid ... 174 3e-43
D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein. 173 4e-43
BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase fam... 173 4e-43
BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase fam... 173 4e-43
BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase fam... 173 4e-43
AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase fam... 173 4e-43
AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase prot... 173 4e-43
AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthas... 173 4e-43
AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein. 173 4e-43
S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase hom... 172 1e-42
S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase hom... 171 2e-42
L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid de... 170 4e-42
Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5 be... 170 5e-42
BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase fam... 170 5e-42
BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase fam... 170 5e-42
AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductas... 170 5e-42
BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase fam... 168 2e-41
D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase... 167 3e-41
S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase pro... 167 4e-41
D26125-1|BAA05122.1| 321|Homo sapiens 3 alpha-hydroxysteroid/di... 167 4e-41
AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase fam... 167 4e-41
AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid d... 167 4e-41
AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogena... 167 4e-41
AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogena... 167 4e-41
M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordeco... 162 1e-39
BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein. 161 3e-39
AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase loo... 161 3e-39
AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase rel... 161 3e-39
AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase rel... 141 3e-33
AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase rel... 141 3e-33
AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase fam... 136 6e-32
AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase fam... 132 1e-30
AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase fam... 132 1e-30
AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase fam... 131 3e-30
BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase fam... 115 2e-25
BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase fam... 115 2e-25
AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens ... 115 2e-25
AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase rel... 111 2e-24
AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto red... 108 2e-23
AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens ... 69 2e-11
AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthas... 50 9e-06
L35546-1|AAA65028.1| 274|Homo sapiens gamma-glutamylcysteine sy... 48 5e-05
CR541833-1|CAG46632.1| 274|Homo sapiens GCLM protein. 48 5e-05
BC041809-1|AAH41809.1| 274|Homo sapiens glutamate-cysteine liga... 48 5e-05
AY773965-1|AAV28733.1| 274|Homo sapiens glutamate-cysteine liga... 48 5e-05
AL117351-10|CAI22976.1| 274|Homo sapiens glutamate-cysteine lig... 48 5e-05
AL049796-2|CAI21813.1| 274|Homo sapiens glutamate-cysteine liga... 48 5e-05
AF026947-1|AAC52104.1| 330|Homo sapiens aflatoxin aldehyde redu... 34 0.65
Y16675-1|CAA76347.1| 330|Homo sapiens aflatoxin B1-aldehyde red... 33 0.86
BT007347-1|AAP36011.1| 330|Homo sapiens aldo-keto reductase fam... 33 0.86
BC013996-1|AAH13996.1| 330|Homo sapiens AKR7A2 protein protein. 33 0.86
BC012171-1|AAH12171.1| 330|Homo sapiens AKR7A2 protein protein. 33 0.86
BC011586-1|AAH11586.1| 330|Homo sapiens AKR7A2 protein protein. 33 0.86
BC010852-1|AAH10852.1| 330|Homo sapiens AKR7A2 protein protein. 33 0.86
BC007352-1|AAH07352.2| 358|Homo sapiens AKR7A2 protein protein. 33 0.86
BC004111-1|AAH04111.3| 330|Homo sapiens AKR7A2 protein protein. 33 0.86
AL035413-8|CAB72321.1| 330|Homo sapiens aldo-keto reductase fam... 33 0.86
AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto red... 33 1.1
AY368652-1|AAQ72693.1| 135|Homo sapiens multiple myeloma suscep... 31 3.5
Y18880-1|CAB56154.1| 715|Homo sapiens midline 2 protein protein. 31 6.1
BT006663-1|AAP35309.1| 685|Homo sapiens midline 2 protein. 31 6.1
BC017707-1|AAH17707.1| 685|Homo sapiens midline 2 protein. 31 6.1
AY625004-1|AAT48105.1| 685|Homo sapiens TRIM1 beta protein. 31 6.1
AL109946-4|CAO72054.1| 685|Homo sapiens midline 2 protein. 31 6.1
AL109946-3|CAO72053.1| 715|Homo sapiens midline 2 protein. 31 6.1
AL034399-3|CAI42074.1| 685|Homo sapiens midline 2 protein. 31 6.1
AL034399-2|CAI42073.1| 715|Homo sapiens midline 2 protein. 31 6.1
AF196481-1|AAF07341.1| 685|Homo sapiens RING finger protein pro... 31 6.1
J04137-1|AAA35493.1| 538|Homo sapiens protein ( Human 60-kdal r... 30 8.0
AK128093-1|BAC87272.1| 208|Homo sapiens protein ( Homo sapiens ... 30 8.0
>CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 193 bits (470), Expect = 7e-49
Identities = 98/202 (48%), Positives = 133/202 (65%), Gaps = 13/202 (6%)
Frame = +3
Query: 201 LSNGQDMPILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEKID 380
L+NG MPILGLGT+ K PGQV +V+ AID GYRHID A VY+NE EVG AI EK+
Sbjct: 7 LNNGAKMPILGLGTW--KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 381 QGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSVNDKGEDLA 560
+ VVKRE+LF+ +KLW H + V +++L+ L+LDY+DLYL+HWP+ E
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPIGFKPGKEFFP 124
Query: 561 IDH-----------LDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPVVNQ 701
+D LDTW MEE+++ GL KAIG+SNFN Q+E +L + + KP VNQ
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 184
Query: 702 VEINPTLTQHKLVRFCXERSVV 767
+E +P LTQ KL+++C + +V
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIV 206
>J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 192 bits (469), Expect = 9e-49
Identities = 99/204 (48%), Positives = 133/204 (65%), Gaps = 13/204 (6%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEK 374
I L+NG MPILGLGT+ K PGQV +V+ AID GYRHID A VY+NE EVG AI EK
Sbjct: 5 ILLNNGAKMPILGLGTW--KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEK 62
Query: 375 IDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSVNDKGED 554
+ + VVKRE+LF+ +KLW H + V +++L+ L+LDY+DLYL+HWP E
Sbjct: 63 LREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEF 122
Query: 555 LAIDH-----------LDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPVV 695
+D LDTW MEE+++ GL KAIG+SNFN Q+E +L + + KP V
Sbjct: 123 FPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAV 182
Query: 696 NQVEINPTLTQHKLVRFCXERSVV 767
NQ+E +P LTQ KL+++C + +V
Sbjct: 183 NQIECHPYLTQEKLIQYCQSKGIV 206
>X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for
aldose reductase (EC 1.1.1.2). ).
Length = 316
Score = 192 bits (467), Expect = 2e-48
Identities = 98/202 (48%), Positives = 132/202 (65%), Gaps = 13/202 (6%)
Frame = +3
Query: 201 LSNGQDMPILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEKID 380
L+NG MPILGLGT+ K PGQV +V+ AID GYRHID A VY+NE EVG AI EK+
Sbjct: 7 LNNGAKMPILGLGTW--KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 381 QGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSVNDKGEDLA 560
+ VVKRE+LF+ +KLW H + V +++L+ L+LDY+DLYL+HWP E
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 561 IDH-----------LDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPVVNQ 701
+D LDTW MEE+++ GL KAIG+SNFN Q+E +L + + KP VNQ
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 184
Query: 702 VEINPTLTQHKLVRFCXERSVV 767
+E +P LTQ KL+++C + +V
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIV 206
>M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 192 bits (467), Expect = 2e-48
Identities = 98/202 (48%), Positives = 132/202 (65%), Gaps = 13/202 (6%)
Frame = +3
Query: 201 LSNGQDMPILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEKID 380
L+NG MPILGLGT+ K PGQV +V+ AID GYRHID A VY+NE EVG AI EK+
Sbjct: 7 LNNGAKMPILGLGTW--KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 381 QGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSVNDKGEDLA 560
+ VVKRE+LF+ +KLW H + V +++L+ L+LDY+DLYL+HWP E
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 561 IDH-----------LDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPVVNQ 701
+D LDTW MEE+++ GL KAIG+SNFN Q+E +L + + KP VNQ
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 184
Query: 702 VEINPTLTQHKLVRFCXERSVV 767
+E +P LTQ KL+++C + +V
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIV 206
>M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose
reductase mRNA, complete cds. ).
Length = 316
Score = 192 bits (467), Expect = 2e-48
Identities = 98/202 (48%), Positives = 132/202 (65%), Gaps = 13/202 (6%)
Frame = +3
Query: 201 LSNGQDMPILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEKID 380
L+NG MPILGLGT+ K PGQV +V+ AID GYRHID A VY+NE EVG AI EK+
Sbjct: 7 LNNGAKMPILGLGTW--KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 381 QGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSVNDKGEDLA 560
+ VVKRE+LF+ +KLW H + V +++L+ L+LDY+DLYL+HWP E
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 561 IDH-----------LDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPVVNQ 701
+D LDTW MEE+++ GL KAIG+SNFN Q+E +L + + KP VNQ
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 184
Query: 702 VEINPTLTQHKLVRFCXERSVV 767
+E +P LTQ KL+++C + +V
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIV 206
>J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 192 bits (467), Expect = 2e-48
Identities = 98/202 (48%), Positives = 132/202 (65%), Gaps = 13/202 (6%)
Frame = +3
Query: 201 LSNGQDMPILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEKID 380
L+NG MPILGLGT+ K PGQV +V+ AID GYRHID A VY+NE EVG AI EK+
Sbjct: 7 LNNGAKMPILGLGTW--KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 381 QGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSVNDKGEDLA 560
+ VVKRE+LF+ +KLW H + V +++L+ L+LDY+DLYL+HWP E
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 561 IDH-----------LDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPVVNQ 701
+D LDTW MEE+++ GL KAIG+SNFN Q+E +L + + KP VNQ
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 184
Query: 702 VEINPTLTQHKLVRFCXERSVV 767
+E +P LTQ KL+++C + +V
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIV 206
>J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 192 bits (467), Expect = 2e-48
Identities = 98/202 (48%), Positives = 132/202 (65%), Gaps = 13/202 (6%)
Frame = +3
Query: 201 LSNGQDMPILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEKID 380
L+NG MPILGLGT+ K PGQV +V+ AID GYRHID A VY+NE EVG AI EK+
Sbjct: 7 LNNGAKMPILGLGTW--KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 381 QGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSVNDKGEDLA 560
+ VVKRE+LF+ +KLW H + V +++L+ L+LDY+DLYL+HWP E
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 561 IDH-----------LDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPVVNQ 701
+D LDTW MEE+++ GL KAIG+SNFN Q+E +L + + KP VNQ
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 184
Query: 702 VEINPTLTQHKLVRFCXERSVV 767
+E +P LTQ KL+++C + +V
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIV 206
>BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 192 bits (467), Expect = 2e-48
Identities = 98/202 (48%), Positives = 132/202 (65%), Gaps = 13/202 (6%)
Frame = +3
Query: 201 LSNGQDMPILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEKID 380
L+NG MPILGLGT+ K PGQV +V+ AID GYRHID A VY+NE EVG AI EK+
Sbjct: 7 LNNGAKMPILGLGTW--KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 381 QGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSVNDKGEDLA 560
+ VVKRE+LF+ +KLW H + V +++L+ L+LDY+DLYL+HWP E
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 561 IDH-----------LDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPVVNQ 701
+D LDTW MEE+++ GL KAIG+SNFN Q+E +L + + KP VNQ
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 184
Query: 702 VEINPTLTQHKLVRFCXERSVV 767
+E +P LTQ KL+++C + +V
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIV 206
>BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 192 bits (467), Expect = 2e-48
Identities = 98/202 (48%), Positives = 132/202 (65%), Gaps = 13/202 (6%)
Frame = +3
Query: 201 LSNGQDMPILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEKID 380
L+NG MPILGLGT+ K PGQV +V+ AID GYRHID A VY+NE EVG AI EK+
Sbjct: 7 LNNGAKMPILGLGTW--KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 381 QGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSVNDKGEDLA 560
+ VVKRE+LF+ +KLW H + V +++L+ L+LDY+DLYL+HWP E
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 561 IDH-----------LDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPVVNQ 701
+D LDTW MEE+++ GL KAIG+SNFN Q+E +L + + KP VNQ
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 184
Query: 702 VEINPTLTQHKLVRFCXERSVV 767
+E +P LTQ KL+++C + +V
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIV 206
>BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 192 bits (467), Expect = 2e-48
Identities = 98/202 (48%), Positives = 132/202 (65%), Gaps = 13/202 (6%)
Frame = +3
Query: 201 LSNGQDMPILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEKID 380
L+NG MPILGLGT+ K PGQV +V+ AID GYRHID A VY+NE EVG AI EK+
Sbjct: 7 LNNGAKMPILGLGTW--KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 381 QGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSVNDKGEDLA 560
+ VVKRE+LF+ +KLW H + V +++L+ L+LDY+DLYL+HWP E
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 561 IDH-----------LDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPVVNQ 701
+D LDTW MEE+++ GL KAIG+SNFN Q+E +L + + KP VNQ
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 184
Query: 702 VEINPTLTQHKLVRFCXERSVV 767
+E +P LTQ KL+++C + +V
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIV 206
>AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen
HD-CL-07 protein.
Length = 316
Score = 192 bits (467), Expect = 2e-48
Identities = 98/202 (48%), Positives = 132/202 (65%), Gaps = 13/202 (6%)
Frame = +3
Query: 201 LSNGQDMPILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEKID 380
L+NG MPILGLGT+ K PGQV +V+ AID GYRHID A VY+NE EVG AI EK+
Sbjct: 7 LNNGAKMPILGLGTW--KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 381 QGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSVNDKGEDLA 560
+ VVKRE+LF+ +KLW H + V +++L+ L+LDY+DLYL+HWP E
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 561 IDH-----------LDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPVVNQ 701
+D LDTW MEE+++ GL KAIG+SNFN Q+E +L + + KP VNQ
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 184
Query: 702 VEINPTLTQHKLVRFCXERSVV 767
+E +P LTQ KL+++C + +V
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIV 206
>AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 192 bits (467), Expect = 2e-48
Identities = 98/202 (48%), Positives = 132/202 (65%), Gaps = 13/202 (6%)
Frame = +3
Query: 201 LSNGQDMPILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEKID 380
L+NG MPILGLGT+ K PGQV +V+ AID GYRHID A VY+NE EVG AI EK+
Sbjct: 7 LNNGAKMPILGLGTW--KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 381 QGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSVNDKGEDLA 560
+ VVKRE+LF+ +KLW H + V +++L+ L+LDY+DLYL+HWP E
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 561 IDH-----------LDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPVVNQ 701
+D LDTW MEE+++ GL KAIG+SNFN Q+E +L + + KP VNQ
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 184
Query: 702 VEINPTLTQHKLVRFCXERSVV 767
+E +P LTQ KL+++C + +V
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIV 206
>AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase family
1, member B1 variant protein.
Length = 260
Score = 192 bits (467), Expect = 2e-48
Identities = 98/202 (48%), Positives = 132/202 (65%), Gaps = 13/202 (6%)
Frame = +3
Query: 201 LSNGQDMPILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEKID 380
L+NG MPILGLGT+ K PGQV +V+ AID GYRHID A VY+NE EVG AI EK+
Sbjct: 4 LNNGAKMPILGLGTW--KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 61
Query: 381 QGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSVNDKGEDLA 560
+ VVKRE+LF+ +KLW H + V +++L+ L+LDY+DLYL+HWP E
Sbjct: 62 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 121
Query: 561 IDH-----------LDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPVVNQ 701
+D LDTW MEE+++ GL KAIG+SNFN Q+E +L + + KP VNQ
Sbjct: 122 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 181
Query: 702 VEINPTLTQHKLVRFCXERSVV 767
+E +P LTQ KL+++C + +V
Sbjct: 182 IECHPYLTQEKLIQYCQSKGIV 203
>CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 191 bits (466), Expect = 2e-48
Identities = 98/202 (48%), Positives = 132/202 (65%), Gaps = 13/202 (6%)
Frame = +3
Query: 201 LSNGQDMPILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEKID 380
L+NG MPILGLGT+ K PGQV +V+ AID GYRHID A VY+NE EVG AI EK+
Sbjct: 7 LNNGAKMPILGLGTW--KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 381 QGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSVNDKGEDLA 560
+ VVKRE+LF+ +KLW H + V +++L+ L+LDY+DLYL+HWP E
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFRPGKEFFP 124
Query: 561 IDH-----------LDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPVVNQ 701
+D LDTW MEE+++ GL KAIG+SNFN Q+E +L + + KP VNQ
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILSKPGLKYKPAVNQ 184
Query: 702 VEINPTLTQHKLVRFCXERSVV 767
+E +P LTQ KL+++C + +V
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIV 206
>BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 186 bits (453), Expect = 8e-47
Identities = 97/202 (48%), Positives = 131/202 (64%), Gaps = 13/202 (6%)
Frame = +3
Query: 201 LSNGQDMPILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEKID 380
L+NG MPILGLGT+ K PGQV +V+ AID GYRHID A VY+NE EVG AI EK+
Sbjct: 7 LNNGAKMPILGLGTW--KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 381 QGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSVNDKGEDLA 560
+ VVKRE+LF+ +KLW H + V +++L+ L+LDY+DLYL+HWP E
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 561 IDH-----------LDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPVVNQ 701
+D LDT MEE+++ GL KAIG+SNFN Q+E +L + + KP VNQ
Sbjct: 125 LDESGNVVPSDTNILDTRAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 184
Query: 702 VEINPTLTQHKLVRFCXERSVV 767
+E +P LTQ KL+++C + +V
Sbjct: 185 IECHPYLTQEKLIQYCQSKGIV 206
>J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein.
Length = 325
Score = 184 bits (447), Expect = 4e-46
Identities = 92/202 (45%), Positives = 132/202 (65%), Gaps = 12/202 (5%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEK 374
+ L GQ MP++GLGT+ K EPGQV +V++A+ GYRHID A +Y NE E+GEA+ E
Sbjct: 6 VLLHTGQKMPLIGLGTW--KSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKED 63
Query: 375 IDQG-VVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSVN---- 539
+ G V RE+LFVT+KLWN KH DV P L+++LA L+L+Y+DLYL+HWP +
Sbjct: 64 VGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDN 123
Query: 540 --DKGEDLAI-----DHLDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATVKPVVN 698
K D I + +TWK +E ++ GL +A+G+SNFN Q++ +L A+V+P V
Sbjct: 124 PFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVL 183
Query: 699 QVEINPTLTQHKLVRFCXERSV 764
QVE +P L Q++L+ C R +
Sbjct: 184 QVECHPYLAQNELIAHCQARGL 205
>CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein.
Length = 325
Score = 184 bits (447), Expect = 4e-46
Identities = 92/202 (45%), Positives = 132/202 (65%), Gaps = 12/202 (5%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEK 374
+ L GQ MP++GLGT+ K EPGQV +V++A+ GYRHID A +Y NE E+GEA+ E
Sbjct: 6 VLLHTGQKMPLIGLGTW--KSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKED 63
Query: 375 IDQG-VVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSVN---- 539
+ G V RE+LFVT+KLWN KH DV P L+++LA L+L+Y+DLYL+HWP +
Sbjct: 64 VGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDN 123
Query: 540 --DKGEDLAI-----DHLDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATVKPVVN 698
K D I + +TWK +E ++ GL +A+G+SNFN Q++ +L A+V+P V
Sbjct: 124 PFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVL 183
Query: 699 QVEINPTLTQHKLVRFCXERSV 764
QVE +P L Q++L+ C R +
Sbjct: 184 QVECHPYLAQNELIAHCQARGL 205
>BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 184 bits (447), Expect = 4e-46
Identities = 92/202 (45%), Positives = 132/202 (65%), Gaps = 12/202 (5%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEK 374
+ L GQ MP++GLGT+ K EPGQV +V++A+ GYRHID A +Y NE E+GEA+ E
Sbjct: 6 VLLHTGQKMPLIGLGTW--KSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKED 63
Query: 375 IDQG-VVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSVN---- 539
+ G V RE+LFVT+KLWN KH DV P L+++LA L+L+Y+DLYL+HWP +
Sbjct: 64 VGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDN 123
Query: 540 --DKGEDLAI-----DHLDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATVKPVVN 698
K D I + +TWK +E ++ GL +A+G+SNFN Q++ +L A+V+P V
Sbjct: 124 PFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVL 183
Query: 699 QVEINPTLTQHKLVRFCXERSV 764
QVE +P L Q++L+ C R +
Sbjct: 184 QVECHPYLAQNELIAHCQARGL 205
>BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 184 bits (447), Expect = 4e-46
Identities = 92/202 (45%), Positives = 132/202 (65%), Gaps = 12/202 (5%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEK 374
+ L GQ MP++GLGT+ K EPGQV +V++A+ GYRHID A +Y NE E+GEA+ E
Sbjct: 6 VLLHTGQKMPLIGLGTW--KSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKED 63
Query: 375 IDQG-VVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSVN---- 539
+ G V RE+LFVT+KLWN KH DV P L+++LA L+L+Y+DLYL+HWP +
Sbjct: 64 VGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDN 123
Query: 540 --DKGEDLAI-----DHLDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATVKPVVN 698
K D I + +TWK +E ++ GL +A+G+SNFN Q++ +L A+V+P V
Sbjct: 124 PFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVL 183
Query: 699 QVEINPTLTQHKLVRFCXERSV 764
QVE +P L Q++L+ C R +
Sbjct: 184 QVECHPYLAQNELIAHCQARGL 205
>BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 184 bits (447), Expect = 4e-46
Identities = 92/202 (45%), Positives = 132/202 (65%), Gaps = 12/202 (5%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEK 374
+ L GQ MP++GLGT+ K EPGQV +V++A+ GYRHID A +Y NE E+GEA+ E
Sbjct: 6 VLLHTGQKMPLIGLGTW--KSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKED 63
Query: 375 IDQG-VVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSVN---- 539
+ G V RE+LFVT+KLWN KH DV P L+++LA L+L+Y+DLYL+HWP +
Sbjct: 64 VGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDN 123
Query: 540 --DKGEDLAI-----DHLDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATVKPVVN 698
K D I + +TWK +E ++ GL +A+G+SNFN Q++ +L A+V+P V
Sbjct: 124 PFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVL 183
Query: 699 QVEINPTLTQHKLVRFCXERSV 764
QVE +P L Q++L+ C R +
Sbjct: 184 QVECHPYLAQNELIAHCQARGL 205
>AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydetase, 1 protein.
Length = 325
Score = 184 bits (447), Expect = 4e-46
Identities = 92/202 (45%), Positives = 132/202 (65%), Gaps = 12/202 (5%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEK 374
+ L GQ MP++GLGT+ K EPGQV +V++A+ GYRHID A +Y NE E+GEA+ E
Sbjct: 6 VLLHTGQKMPLIGLGTW--KSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKED 63
Query: 375 IDQG-VVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSVN---- 539
+ G V RE+LFVT+KLWN KH DV P L+++LA L+L+Y+DLYL+HWP +
Sbjct: 64 VGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDN 123
Query: 540 --DKGEDLAI-----DHLDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATVKPVVN 698
K D I + +TWK +E ++ GL +A+G+SNFN Q++ +L A+V+P V
Sbjct: 124 PFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVL 183
Query: 699 QVEINPTLTQHKLVRFCXERSV 764
QVE +P L Q++L+ C R +
Sbjct: 184 QVECHPYLAQNELIAHCQARGL 205
>AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 184 bits (447), Expect = 4e-46
Identities = 92/202 (45%), Positives = 132/202 (65%), Gaps = 12/202 (5%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEK 374
+ L GQ MP++GLGT+ K EPGQV +V++A+ GYRHID A +Y NE E+GEA+ E
Sbjct: 6 VLLHTGQKMPLIGLGTW--KSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKED 63
Query: 375 IDQG-VVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSVN---- 539
+ G V RE+LFVT+KLWN KH DV P L+++LA L+L+Y+DLYL+HWP +
Sbjct: 64 VGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDN 123
Query: 540 --DKGEDLAI-----DHLDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATVKPVVN 698
K D I + +TWK +E ++ GL +A+G+SNFN Q++ +L A+V+P V
Sbjct: 124 PFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVL 183
Query: 699 QVEINPTLTQHKLVRFCXERSV 764
QVE +P L Q++L+ C R +
Sbjct: 184 QVECHPYLAQNELIAHCQARGL 205
>AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 184 bits (447), Expect = 4e-46
Identities = 92/202 (45%), Positives = 132/202 (65%), Gaps = 12/202 (5%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEK 374
+ L GQ MP++GLGT+ K EPGQV +V++A+ GYRHID A +Y NE E+GEA+ E
Sbjct: 6 VLLHTGQKMPLIGLGTW--KSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKED 63
Query: 375 IDQG-VVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSVN---- 539
+ G V RE+LFVT+KLWN KH DV P L+++LA L+L+Y+DLYL+HWP +
Sbjct: 64 VGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDN 123
Query: 540 --DKGEDLAI-----DHLDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATVKPVVN 698
K D I + +TWK +E ++ GL +A+G+SNFN Q++ +L A+V+P V
Sbjct: 124 PFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVL 183
Query: 699 QVEINPTLTQHKLVRFCXERSV 764
QVE +P L Q++L+ C R +
Sbjct: 184 QVECHPYLAQNELIAHCQARGL 205
>S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 182 bits (443), Expect = 1e-45
Identities = 98/207 (47%), Positives = 130/207 (62%), Gaps = 14/207 (6%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISE 371
+KL++G MP+LG GTYA P + L +V+ AI+AG+ HID+A VY NE +VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 372 KIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV----- 536
KI G VKRE +F T+KLW++ H V P L+ SL L+LDYVDLYL+H+PVSV
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 537 ---NDKGEDLAIDHLD---TWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATVK--PV 692
D+ + D +D TW+ ME+ + GL K+IGVSNFN LE +L E +K PV
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEPGLKYEPV 187
Query: 693 VNQVEINPTLTQHKLVRFCXERSVVPV 773
NQVE +P Q KL+ FC + +V V
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLV 214
>L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol
dehydrogenase/bile acid-binding protein protein.
Length = 323
Score = 182 bits (443), Expect = 1e-45
Identities = 98/207 (47%), Positives = 129/207 (62%), Gaps = 14/207 (6%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISE 371
+KL++G MP+LG GTYA P + L +V+ AI+AGY HID+A VY NE +VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGYHHIDSAHVYNNEEQVGLAIRS 67
Query: 372 KIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV----- 536
KI G VKRE +F T+KLW++ H V P L+ SL L+LDY DLYL+H+PVSV
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYADLYLIHFPVSVKPGEE 127
Query: 537 ---NDKGEDLAIDHLD---TWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATVK--PV 692
D+ + D +D TW+ ME+ + GL K+IGVSNFN LE +L E +K PV
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEPGLKYEPV 187
Query: 693 VNQVEINPTLTQHKLVRFCXERSVVPV 773
NQVE +P Q KL+ FC + +V V
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLV 214
>U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 180 bits (439), Expect = 4e-45
Identities = 97/207 (46%), Positives = 130/207 (62%), Gaps = 14/207 (6%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISE 371
+KL++G MP+LG GTYA P + L +V+ AI+AG+ HID+A VY NE +VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 372 KIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV----- 536
KI G VKRE +F T+KLW++ H V P L+ SL L+LDYVDLYL+H+PVSV
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 537 ---NDKGEDLAIDHLD---TWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPV 692
D+ + D +D TW+ ME+ + GL K+IGVSNFN LE +L + + KPV
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 693 VNQVEINPTLTQHKLVRFCXERSVVPV 773
NQVE +P Q KL+ FC + +V V
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLV 214
>BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 180 bits (439), Expect = 4e-45
Identities = 97/207 (46%), Positives = 130/207 (62%), Gaps = 14/207 (6%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISE 371
+KL++G MP+LG GTYA P + L +V+ AI+AG+ HID+A VY NE +VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 372 KIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV----- 536
KI G VKRE +F T+KLW++ H V P L+ SL L+LDYVDLYL+H+PVSV
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 537 ---NDKGEDLAIDHLD---TWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPV 692
D+ + D +D TW+ ME+ + GL K+IGVSNFN LE +L + + KPV
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 693 VNQVEINPTLTQHKLVRFCXERSVVPV 773
NQVE +P Q KL+ FC + +V V
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLV 214
>BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 180 bits (439), Expect = 4e-45
Identities = 97/207 (46%), Positives = 130/207 (62%), Gaps = 14/207 (6%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISE 371
+KL++G MP+LG GTYA P + L +V+ AI+AG+ HID+A VY NE +VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 372 KIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV----- 536
KI G VKRE +F T+KLW++ H V P L+ SL L+LDYVDLYL+H+PVSV
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 537 ---NDKGEDLAIDHLD---TWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPV 692
D+ + D +D TW+ ME+ + GL K+IGVSNFN LE +L + + KPV
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 693 VNQVEINPTLTQHKLVRFCXERSVVPV 773
NQVE +P Q KL+ FC + +V V
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLV 214
>BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 180 bits (439), Expect = 4e-45
Identities = 97/207 (46%), Positives = 130/207 (62%), Gaps = 14/207 (6%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISE 371
+KL++G MP+LG GTYA P + L +V+ AI+AG+ HID+A VY NE +VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 372 KIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV----- 536
KI G VKRE +F T+KLW++ H V P L+ SL L+LDYVDLYL+H+PVSV
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 537 ---NDKGEDLAIDHLD---TWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPV 692
D+ + D +D TW+ ME+ + GL K+IGVSNFN LE +L + + KPV
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 693 VNQVEINPTLTQHKLVRFCXERSVVPV 773
NQVE +P Q KL+ FC + +V V
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLV 214
>AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 180 bits (439), Expect = 4e-45
Identities = 97/207 (46%), Positives = 130/207 (62%), Gaps = 14/207 (6%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISE 371
+KL++G MP+LG GTYA P + L +V+ AI+AG+ HID+A VY NE +VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 372 KIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV----- 536
KI G VKRE +F T+KLW++ H V P L+ SL L+LDYVDLYL+H+PVSV
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 537 ---NDKGEDLAIDHLD---TWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPV 692
D+ + D +D TW+ ME+ + GL K+IGVSNFN LE +L + + KPV
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 693 VNQVEINPTLTQHKLVRFCXERSVVPV 773
NQVE +P Q KL+ FC + +V V
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLV 214
>AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 180 bits (439), Expect = 4e-45
Identities = 97/207 (46%), Positives = 130/207 (62%), Gaps = 14/207 (6%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISE 371
+KL++G MP+LG GTYA P + L +V+ AI+AG+ HID+A VY NE +VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 372 KIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV----- 536
KI G VKRE +F T+KLW++ H V P L+ SL L+LDYVDLYL+H+PVSV
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 537 ---NDKGEDLAIDHLD---TWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPV 692
D+ + D +D TW+ ME+ + GL K+IGVSNFN LE +L + + KPV
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 693 VNQVEINPTLTQHKLVRFCXERSVVPV 773
NQVE +P Q KL+ FC + +V V
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLV 214
>AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase family
1, member C2 variant protein.
Length = 286
Score = 180 bits (439), Expect = 4e-45
Identities = 97/207 (46%), Positives = 130/207 (62%), Gaps = 14/207 (6%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISE 371
+KL++G MP+LG GTYA P + L +V+ AI+AG+ HID+A VY NE +VG AI
Sbjct: 21 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 80
Query: 372 KIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV----- 536
KI G VKRE +F T+KLW++ H V P L+ SL L+LDYVDLYL+H+PVSV
Sbjct: 81 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 140
Query: 537 ---NDKGEDLAIDHLD---TWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPV 692
D+ + D +D TW+ ME+ + GL K+IGVSNFN LE +L + + KPV
Sbjct: 141 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 200
Query: 693 VNQVEINPTLTQHKLVRFCXERSVVPV 773
NQVE +P Q KL+ FC + +V V
Sbjct: 201 CNQVECHPYFNQRKLLDFCKSKDIVLV 227
>AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 180 bits (439), Expect = 4e-45
Identities = 97/207 (46%), Positives = 130/207 (62%), Gaps = 14/207 (6%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISE 371
+KL++G MP+LG GTYA P + L +V+ AI+AG+ HID+A VY NE +VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 372 KIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV----- 536
KI G VKRE +F T+KLW++ H V P L+ SL L+LDYVDLYL+H+PVSV
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 537 ---NDKGEDLAIDHLD---TWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPV 692
D+ + D +D TW+ ME+ + GL K+IGVSNFN LE +L + + KPV
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 693 VNQVEINPTLTQHKLVRFCXERSVVPV 773
NQVE +P Q KL+ FC + +V V
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLV 214
>AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 180 bits (439), Expect = 4e-45
Identities = 97/207 (46%), Positives = 130/207 (62%), Gaps = 14/207 (6%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISE 371
+KL++G MP+LG GTYA P + L +V+ AI+AG+ HID+A VY NE +VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 372 KIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV----- 536
KI G VKRE +F T+KLW++ H V P L+ SL L+LDYVDLYL+H+PVSV
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 537 ---NDKGEDLAIDHLD---TWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPV 692
D+ + D +D TW+ ME+ + GL K+IGVSNFN LE +L + + KPV
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 693 VNQVEINPTLTQHKLVRFCXERSVVPV 773
NQVE +P Q KL+ FC + +V V
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLV 214
>AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding
protein/AKR1C2/3alpha-hydroxysteroid dehydrogenase type
3 protein.
Length = 323
Score = 180 bits (439), Expect = 4e-45
Identities = 97/207 (46%), Positives = 130/207 (62%), Gaps = 14/207 (6%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISE 371
+KL++G MP+LG GTYA P + L +V+ AI+AG+ HID+A VY NE +VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 372 KIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV----- 536
KI G VKRE +F T+KLW++ H V P L+ SL L+LDYVDLYL+H+PVSV
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 537 ---NDKGEDLAIDHLD---TWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPV 692
D+ + D +D TW+ ME+ + GL K+IGVSNFN LE +L + + KPV
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
Query: 693 VNQVEINPTLTQHKLVRFCXERSVVPV 773
NQVE +P Q KL+ FC + +V V
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLV 214
>U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol
dehydrogenase protein.
Length = 323
Score = 179 bits (436), Expect = 9e-45
Identities = 96/207 (46%), Positives = 130/207 (62%), Gaps = 14/207 (6%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISE 371
+KL++G MP+LG GTYA P + L + + AI+AG+RHID+A +Y NE +VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 372 KIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV----- 536
KI G VKRE +F T+KLW + H V P L+ SL L+LDYVDLYL+H+PVSV
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 537 ---NDKGEDLAIDHLD---TWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPV 692
D+ + D +D TW+ +E+ + GL K+IGVSNFN QLE +L + + KPV
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 693 VNQVEINPTLTQHKLVRFCXERSVVPV 773
NQVE +P Q KL+ FC + +V V
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLV 214
>U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 179 bits (436), Expect = 9e-45
Identities = 96/207 (46%), Positives = 130/207 (62%), Gaps = 14/207 (6%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISE 371
+KL++G MP+LG GTYA P + L + + AI+AG+RHID+A +Y NE +VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 372 KIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV----- 536
KI G VKRE +F T+KLW + H V P L+ SL L+LDYVDLYL+H+PVSV
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 537 ---NDKGEDLAIDHLD---TWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPV 692
D+ + D +D TW+ +E+ + GL K+IGVSNFN QLE +L + + KPV
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 693 VNQVEINPTLTQHKLVRFCXERSVVPV 773
NQVE +P Q KL+ FC + +V V
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLV 214
>M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 179 bits (436), Expect = 9e-45
Identities = 96/207 (46%), Positives = 130/207 (62%), Gaps = 14/207 (6%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISE 371
+KL++G MP+LG GTYA P + L + + AI+AG+RHID+A +Y NE +VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 372 KIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV----- 536
KI G VKRE +F T+KLW + H V P L+ SL L+LDYVDLYL+H+PVSV
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 537 ---NDKGEDLAIDHLD---TWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPV 692
D+ + D +D TW+ +E+ + GL K+IGVSNFN QLE +L + + KPV
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 693 VNQVEINPTLTQHKLVRFCXERSVVPV 773
NQVE +P Q KL+ FC + +V V
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLV 214
>BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 179 bits (436), Expect = 9e-45
Identities = 96/207 (46%), Positives = 130/207 (62%), Gaps = 14/207 (6%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISE 371
+KL++G MP+LG GTYA P + L + + AI+AG+RHID+A +Y NE +VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 372 KIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV----- 536
KI G VKRE +F T+KLW + H V P L+ SL L+LDYVDLYL+H+PVSV
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 537 ---NDKGEDLAIDHLD---TWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPV 692
D+ + D +D TW+ +E+ + GL K+IGVSNFN QLE +L + + KPV
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 693 VNQVEINPTLTQHKLVRFCXERSVVPV 773
NQVE +P Q KL+ FC + +V V
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLV 214
>BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 179 bits (436), Expect = 9e-45
Identities = 96/207 (46%), Positives = 130/207 (62%), Gaps = 14/207 (6%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISE 371
+KL++G MP+LG GTYA P + L + + AI+AG+RHID+A +Y NE +VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 372 KIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV----- 536
KI G VKRE +F T+KLW + H V P L+ SL L+LDYVDLYL+H+PVSV
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 537 ---NDKGEDLAIDHLD---TWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPV 692
D+ + D +D TW+ +E+ + GL K+IGVSNFN QLE +L + + KPV
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 693 VNQVEINPTLTQHKLVRFCXERSVVPV 773
NQVE +P Q KL+ FC + +V V
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLV 214
>BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 179 bits (436), Expect = 9e-45
Identities = 96/207 (46%), Positives = 130/207 (62%), Gaps = 14/207 (6%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISE 371
+KL++G MP+LG GTYA P + L + + AI+AG+RHID+A +Y NE +VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 372 KIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV----- 536
KI G VKRE +F T+KLW + H V P L+ SL L+LDYVDLYL+H+PVSV
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 537 ---NDKGEDLAIDHLD---TWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPV 692
D+ + D +D TW+ +E+ + GL K+IGVSNFN QLE +L + + KPV
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 693 VNQVEINPTLTQHKLVRFCXERSVVPV 773
NQVE +P Q KL+ FC + +V V
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLV 214
>BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 179 bits (436), Expect = 9e-45
Identities = 96/207 (46%), Positives = 130/207 (62%), Gaps = 14/207 (6%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISE 371
+KL++G MP+LG GTYA P + L + + AI+AG+RHID+A +Y NE +VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 372 KIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV----- 536
KI G VKRE +F T+KLW + H V P L+ SL L+LDYVDLYL+H+PVSV
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 537 ---NDKGEDLAIDHLD---TWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPV 692
D+ + D +D TW+ +E+ + GL K+IGVSNFN QLE +L + + KPV
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 693 VNQVEINPTLTQHKLVRFCXERSVVPV 773
NQVE +P Q KL+ FC + +V V
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLV 214
>AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 179 bits (436), Expect = 9e-45
Identities = 96/207 (46%), Positives = 130/207 (62%), Gaps = 14/207 (6%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISE 371
+KL++G MP+LG GTYA P + L + + AI+AG+RHID+A +Y NE +VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 372 KIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV----- 536
KI G VKRE +F T+KLW + H V P L+ SL L+LDYVDLYL+H+PVSV
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 537 ---NDKGEDLAIDHLD---TWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPV 692
D+ + D +D TW+ +E+ + GL K+IGVSNFN QLE +L + + KPV
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 693 VNQVEINPTLTQHKLVRFCXERSVVPV 773
NQVE +P Q KL+ FC + +V V
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLV 214
>AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 179 bits (436), Expect = 9e-45
Identities = 96/207 (46%), Positives = 130/207 (62%), Gaps = 14/207 (6%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISE 371
+KL++G MP+LG GTYA P + L + + AI+AG+RHID+A +Y NE +VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 372 KIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV----- 536
KI G VKRE +F T+KLW + H V P L+ SL L+LDYVDLYL+H+PVSV
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 537 ---NDKGEDLAIDHLD---TWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPV 692
D+ + D +D TW+ +E+ + GL K+IGVSNFN QLE +L + + KPV
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 693 VNQVEINPTLTQHKLVRFCXERSVVPV 773
NQVE +P Q KL+ FC + +V V
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLV 214
>AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 179 bits (436), Expect = 9e-45
Identities = 96/207 (46%), Positives = 130/207 (62%), Gaps = 14/207 (6%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISE 371
+KL++G MP+LG GTYA P + L + + AI+AG+RHID+A +Y NE +VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 372 KIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV----- 536
KI G VKRE +F T+KLW + H V P L+ SL L+LDYVDLYL+H+PVSV
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 537 ---NDKGEDLAIDHLD---TWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPV 692
D+ + D +D TW+ +E+ + GL K+IGVSNFN QLE +L + + KPV
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
Query: 693 VNQVEINPTLTQHKLVRFCXERSVVPV 773
NQVE +P Q KL+ FC + +V V
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLV 214
>U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like
peptide protein.
Length = 316
Score = 176 bits (429), Expect = 6e-44
Identities = 94/203 (46%), Positives = 130/203 (64%), Gaps = 13/203 (6%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEK 374
++LS MPI+GLGT+ K G+V +V+ AIDAGYRHID A VY+NE EVGEAI EK
Sbjct: 5 VELSTKAKMPIVGLGTW--KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEK 62
Query: 375 IDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV------ 536
I + VKRE LF+ +KLW R V +++L L+L Y+D+YL+HWP
Sbjct: 63 IQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDL 122
Query: 537 ---NDKGEDLA--IDHLDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPVV 695
+DKG + LD W+ MEE+++ GL KA+GVSNF+ Q+E+LL + + KPV
Sbjct: 123 FPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVT 182
Query: 696 NQVEINPTLTQHKLVRFCXERSV 764
NQVE +P LTQ KL+++C + +
Sbjct: 183 NQVECHPYLTQEKLIQYCHSKGI 205
>CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein.
Length = 316
Score = 176 bits (429), Expect = 6e-44
Identities = 94/203 (46%), Positives = 130/203 (64%), Gaps = 13/203 (6%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEK 374
++LS MPI+GLGT+ K G+V +V+ AIDAGYRHID A VY+NE EVGEAI EK
Sbjct: 5 VELSTKAKMPIVGLGTW--KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEK 62
Query: 375 IDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV------ 536
I + VKRE LF+ +KLW R V +++L L+L Y+D+YL+HWP
Sbjct: 63 IQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDL 122
Query: 537 ---NDKGEDLA--IDHLDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPVV 695
+DKG + LD W+ MEE+++ GL KA+GVSNF+ Q+E+LL + + KPV
Sbjct: 123 FPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVT 182
Query: 696 NQVEINPTLTQHKLVRFCXERSV 764
NQVE +P LTQ KL+++C + +
Sbjct: 183 NQVECHPYLTQEKLIQYCHSKGI 205
>BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 176 bits (429), Expect = 6e-44
Identities = 94/203 (46%), Positives = 130/203 (64%), Gaps = 13/203 (6%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEK 374
++LS MPI+GLGT+ K G+V +V+ AIDAGYRHID A VY+NE EVGEAI EK
Sbjct: 5 VELSTKAKMPIVGLGTW--KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEK 62
Query: 375 IDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV------ 536
I + VKRE LF+ +KLW R V +++L L+L Y+D+YL+HWP
Sbjct: 63 IQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDL 122
Query: 537 ---NDKGEDLA--IDHLDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPVV 695
+DKG + LD W+ MEE+++ GL KA+GVSNF+ Q+E+LL + + KPV
Sbjct: 123 FPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVT 182
Query: 696 NQVEINPTLTQHKLVRFCXERSV 764
NQVE +P LTQ KL+++C + +
Sbjct: 183 NQVECHPYLTQEKLIQYCHSKGI 205
>BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 176 bits (429), Expect = 6e-44
Identities = 94/203 (46%), Positives = 130/203 (64%), Gaps = 13/203 (6%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEK 374
++LS MPI+GLGT+ K G+V +V+ AIDAGYRHID A VY+NE EVGEAI EK
Sbjct: 5 VELSTKAKMPIVGLGTW--KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEK 62
Query: 375 IDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV------ 536
I + VKRE LF+ +KLW R V +++L L+L Y+D+YL+HWP
Sbjct: 63 IQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDL 122
Query: 537 ---NDKGEDLA--IDHLDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPVV 695
+DKG + LD W+ MEE+++ GL KA+GVSNF+ Q+E+LL + + KPV
Sbjct: 123 FPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVT 182
Query: 696 NQVEINPTLTQHKLVRFCXERSV 764
NQVE +P LTQ KL+++C + +
Sbjct: 183 NQVECHPYLTQEKLIQYCHSKGI 205
>AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase
protein.
Length = 316
Score = 176 bits (429), Expect = 6e-44
Identities = 94/203 (46%), Positives = 130/203 (64%), Gaps = 13/203 (6%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEK 374
++LS MPI+GLGT+ K G+V +V+ AIDAGYRHID A VY+NE EVGEAI EK
Sbjct: 5 VELSTKAKMPIVGLGTW--KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEK 62
Query: 375 IDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV------ 536
I + VKRE LF+ +KLW R V +++L L+L Y+D+YL+HWP
Sbjct: 63 IQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDL 122
Query: 537 ---NDKGEDLA--IDHLDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPVV 695
+DKG + LD W+ MEE+++ GL KA+GVSNF+ Q+E+LL + + KPV
Sbjct: 123 FPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVT 182
Query: 696 NQVEINPTLTQHKLVRFCXERSV 764
NQVE +P LTQ KL+++C + +
Sbjct: 183 NQVECHPYLTQEKLIQYCHSKGI 205
>DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 175 bits (425), Expect = 2e-43
Identities = 94/208 (45%), Positives = 130/208 (62%), Gaps = 15/208 (7%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISE 371
+KL++G MP+LG GTYA P + L + + AI+AG+RHID+A +Y NE +VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAVRS 67
Query: 372 KIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSVNDKGE 551
KI G VKRE +F T+KLW + H V P L+ SL K +LDYVDLYL+H P+S+ GE
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKKAQLDYVDLYLIHSPMSLK-PGE 126
Query: 552 DLA------------IDHLDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KP 689
+L+ +D TW+ ME+ + GL K+IGVSNFN QLE +L + + KP
Sbjct: 127 ELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKP 186
Query: 690 VVNQVEINPTLTQHKLVRFCXERSVVPV 773
V NQVE +P + KL+ FC + +V V
Sbjct: 187 VCNQVECHPYFNRSKLLDFCKSKDIVLV 214
>AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase type IIb protein.
Length = 323
Score = 174 bits (423), Expect = 3e-43
Identities = 95/208 (45%), Positives = 129/208 (62%), Gaps = 15/208 (7%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISE 371
+KL++G MP+LG GTYA P + L + AI+AG+RHID+A +Y NE +VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVSKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 372 KIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSVNDKGE 551
KI G VKRE +F T+KLW+ H V P L+ SL K +LDYVDLYL+H P+S+ GE
Sbjct: 68 KIADGSVKREDIFYTSKLWSTSHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLK-PGE 126
Query: 552 DLA------------IDHLDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KP 689
+L+ +D TW+ ME+ + GL K+IGVSNFN QLE +L + + KP
Sbjct: 127 ELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKP 186
Query: 690 VVNQVEINPTLTQHKLVRFCXERSVVPV 773
V NQVE +P + KL+ FC + +V V
Sbjct: 187 VCNQVECHPYFNRSKLLDFCKSKDIVLV 214
>D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein.
Length = 325
Score = 173 bits (422), Expect = 4e-43
Identities = 95/208 (45%), Positives = 129/208 (62%), Gaps = 15/208 (7%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISE 371
+KL++G MP+LG GTYA P + L + AI+AG+RHID+A +Y NE +VG AI
Sbjct: 10 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 69
Query: 372 KIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSVNDKGE 551
KI G VKRE +F T+KLW+ H V P L+ SL K +LDYVDLYL+H P+S+ GE
Sbjct: 70 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLK-PGE 128
Query: 552 DLA------------IDHLDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KP 689
+L+ +D TW+ ME+ + GL K+IGVSNFN QLE +L + + KP
Sbjct: 129 ELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKP 188
Query: 690 VVNQVEINPTLTQHKLVRFCXERSVVPV 773
V NQVE +P + KL+ FC + +V V
Sbjct: 189 VCNQVECHPYFNRSKLLDFCKSKDIVLV 216
>BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 173 bits (422), Expect = 4e-43
Identities = 95/208 (45%), Positives = 129/208 (62%), Gaps = 15/208 (7%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISE 371
+KL++G MP+LG GTYA P + L + AI+AG+RHID+A +Y NE +VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 372 KIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSVNDKGE 551
KI G VKRE +F T+KLW+ H V P L+ SL K +LDYVDLYL+H P+S+ GE
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLK-PGE 126
Query: 552 DLA------------IDHLDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KP 689
+L+ +D TW+ ME+ + GL K+IGVSNFN QLE +L + + KP
Sbjct: 127 ELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKP 186
Query: 690 VVNQVEINPTLTQHKLVRFCXERSVVPV 773
V NQVE +P + KL+ FC + +V V
Sbjct: 187 VCNQVECHPYFNRSKLLDFCKSKDIVLV 214
>BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 173 bits (422), Expect = 4e-43
Identities = 95/208 (45%), Positives = 129/208 (62%), Gaps = 15/208 (7%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISE 371
+KL++G MP+LG GTYA P + L + AI+AG+RHID+A +Y NE +VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 372 KIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSVNDKGE 551
KI G VKRE +F T+KLW+ H V P L+ SL K +LDYVDLYL+H P+S+ GE
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLK-PGE 126
Query: 552 DLA------------IDHLDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KP 689
+L+ +D TW+ ME+ + GL K+IGVSNFN QLE +L + + KP
Sbjct: 127 ELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKP 186
Query: 690 VVNQVEINPTLTQHKLVRFCXERSVVPV 773
V NQVE +P + KL+ FC + +V V
Sbjct: 187 VCNQVECHPYFNRSKLLDFCKSKDIVLV 214
>BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 173 bits (422), Expect = 4e-43
Identities = 95/208 (45%), Positives = 129/208 (62%), Gaps = 15/208 (7%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISE 371
+KL++G MP+LG GTYA P + L + AI+AG+RHID+A +Y NE +VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 372 KIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSVNDKGE 551
KI G VKRE +F T+KLW+ H V P L+ SL K +LDYVDLYL+H P+S+ GE
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLK-PGE 126
Query: 552 DLA------------IDHLDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KP 689
+L+ +D TW+ ME+ + GL K+IGVSNFN QLE +L + + KP
Sbjct: 127 ELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKP 186
Query: 690 VVNQVEINPTLTQHKLVRFCXERSVVPV 773
V NQVE +P + KL+ FC + +V V
Sbjct: 187 VCNQVECHPYFNRSKLLDFCKSKDIVLV 214
>AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 173 bits (422), Expect = 4e-43
Identities = 95/208 (45%), Positives = 129/208 (62%), Gaps = 15/208 (7%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISE 371
+KL++G MP+LG GTYA P + L + AI+AG+RHID+A +Y NE +VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 372 KIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSVNDKGE 551
KI G VKRE +F T+KLW+ H V P L+ SL K +LDYVDLYL+H P+S+ GE
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLK-PGE 126
Query: 552 DLA------------IDHLDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KP 689
+L+ +D TW+ ME+ + GL K+IGVSNFN QLE +L + + KP
Sbjct: 127 ELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKP 186
Query: 690 VVNQVEINPTLTQHKLVRFCXERSVVPV 773
V NQVE +P + KL+ FC + +V V
Sbjct: 187 VCNQVECHPYFNRSKLLDFCKSKDIVLV 214
>AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase
protein.
Length = 316
Score = 173 bits (422), Expect = 4e-43
Identities = 93/203 (45%), Positives = 129/203 (63%), Gaps = 13/203 (6%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEK 374
++LS MPI+GLGT+ K G+V +V+ AIDAGYRHID A VY+NE EVGEAI EK
Sbjct: 5 VELSTKAKMPIVGLGTW--KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEK 62
Query: 375 IDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV------ 536
I + VKRE LF+ +KLW R V +++L +L Y+D+YL+HWP
Sbjct: 63 IQEKAVKREDLFIASKLWPTFFERPLVRKAFEKTLKDPKLSYLDVYLIHWPQGFKSGDDL 122
Query: 537 ---NDKGEDLA--IDHLDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPVV 695
+DKG + LD W+ MEE+++ GL KA+GVSNF+ Q+E+LL + + KPV
Sbjct: 123 FPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVT 182
Query: 696 NQVEINPTLTQHKLVRFCXERSV 764
NQVE +P LTQ KL+++C + +
Sbjct: 183 NQVECHPYLTQEKLIQYCHSKGI 205
>AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthase
protein.
Length = 323
Score = 173 bits (422), Expect = 4e-43
Identities = 95/208 (45%), Positives = 129/208 (62%), Gaps = 15/208 (7%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISE 371
+KL++G MP+LG GTYA P + L + AI+AG+RHID+A +Y NE +VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 372 KIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSVNDKGE 551
KI G VKRE +F T+KLW+ H V P L+ SL K +LDYVDLYL+H P+S+ GE
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLK-PGE 126
Query: 552 DLA------------IDHLDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KP 689
+L+ +D TW+ ME+ + GL K+IGVSNFN QLE +L + + KP
Sbjct: 127 ELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKP 186
Query: 690 VVNQVEINPTLTQHKLVRFCXERSVVPV 773
V NQVE +P + KL+ FC + +V V
Sbjct: 187 VCNQVECHPYFNRSKLLDFCKSKDIVLV 214
>AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein.
Length = 323
Score = 173 bits (422), Expect = 4e-43
Identities = 95/208 (45%), Positives = 129/208 (62%), Gaps = 15/208 (7%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISE 371
+KL++G MP+LG GTYA P + L + AI+AG+RHID+A +Y NE +VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 372 KIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSVNDKGE 551
KI G VKRE +F T+KLW+ H V P L+ SL K +LDYVDLYL+H P+S+ GE
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLK-PGE 126
Query: 552 DLA------------IDHLDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KP 689
+L+ +D TW+ ME+ + GL K+IGVSNFN QLE +L + + KP
Sbjct: 127 ELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKP 186
Query: 690 VVNQVEINPTLTQHKLVRFCXERSVVPV 773
V NQVE +P + KL+ FC + +V V
Sbjct: 187 VCNQVECHPYFNRSKLLDFCKSKDIVLV 214
>S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase
homolog protein.
Length = 320
Score = 172 bits (419), Expect = 1e-42
Identities = 94/207 (45%), Positives = 127/207 (61%), Gaps = 14/207 (6%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISE 371
+KL++G MP+LG GTYA P + L + + AI+AG+RHID+A +Y NE +VG AI
Sbjct: 5 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 64
Query: 372 KIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV----- 536
KI G VKRE +F T+KLW + H P L+ SL L+LDYVDLYL+H+PVSV
Sbjct: 65 KIADGSVKREDIFYTSKLWCNSHRPELDRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 124
Query: 537 ---NDKGEDLAIDHLD---TWKGMEEVLELGLTKAIGVSNFNEEQLERLLRE--ATVKPV 692
D+ + D +D TW+ +E+ + L K+IGVSNFN LE +L + VKPV
Sbjct: 125 VIPKDENGKILFDTVDLCATWEAVEKCKDAELAKSIGVSNFNRSTLEMILNKPGLQVKPV 184
Query: 693 VNQVEINPTLTQHKLVRFCXERSVVPV 773
NQVE +P Q KL+ FC + +V V
Sbjct: 185 CNQVECHPYFNQRKLLDFCKSKDIVLV 211
>S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 171 bits (416), Expect = 2e-42
Identities = 94/208 (45%), Positives = 129/208 (62%), Gaps = 15/208 (7%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISE 371
+KL++G MP+LG GTYA P + L + AI+AG+RHID+A +Y NE +VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 372 KIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSVNDKGE 551
KI G V+RE +F T+KLW+ H V P L+ SL K +LDYVDLYL+H P+S+ GE
Sbjct: 68 KIADGSVEREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLK-PGE 126
Query: 552 DLA------------IDHLDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KP 689
+L+ +D TW+ ME+ + GL K+IGVSNFN QLE +L + + KP
Sbjct: 127 ELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKPGLKYKP 186
Query: 690 VVNQVEINPTLTQHKLVRFCXERSVVPV 773
V NQVE +P + KL+ FC + +V V
Sbjct: 187 VCNQVECHPYFNRSKLLDFCKSKDIVLV 214
>L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 170 bits (414), Expect = 4e-42
Identities = 94/208 (45%), Positives = 128/208 (61%), Gaps = 15/208 (7%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISE 371
+KL++G MP+LG GTYA P + L + AI+AG+RHID+A +Y NE +VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 372 KIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSVNDKGE 551
KI G V RE +F T+KLW+ H V P L+ SL K +LDYVDLYL+H P+S+ GE
Sbjct: 68 KIADGSVMREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLK-PGE 126
Query: 552 DLA------------IDHLDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KP 689
+L+ +D TW+ ME+ + GL K+IGVSNFN QLE +L + + KP
Sbjct: 127 ELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKPGLKYKP 186
Query: 690 VVNQVEINPTLTQHKLVRFCXERSVVPV 773
V NQVE +P + KL+ FC + +V V
Sbjct: 187 VCNQVECHPYFNRSKLLDFCKSKDIVLV 214
>Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5
beta-reductase protein.
Length = 326
Score = 170 bits (413), Expect = 5e-42
Identities = 95/206 (46%), Positives = 124/206 (60%), Gaps = 15/206 (7%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYAR-KPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAIS 368
I LS+G +PI+GLGTY+ K P G SV+ AID GYRHID A +Y+NE EVGEAI
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIR 69
Query: 369 EKIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSVNDKG 548
EKI +G V+RE +F KLW H V PTL+ +L L+LDYVDLY++ P++
Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 129
Query: 549 EDLAIDH-----------LDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KP 689
E D TW+ ME + GL K++GVSNFN QLE +L + + KP
Sbjct: 130 EIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKP 189
Query: 690 VVNQVEINPTLTQHKLVRFCXERSVV 767
V NQVE +P TQ KL++FC + +V
Sbjct: 190 VSNQVECHPYFTQPKLLKFCQQHDIV 215
>BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 170 bits (413), Expect = 5e-42
Identities = 95/206 (46%), Positives = 124/206 (60%), Gaps = 15/206 (7%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYAR-KPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAIS 368
I LS+G +PI+GLGTY+ K P G SV+ AID GYRHID A +Y+NE EVGEAI
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIR 69
Query: 369 EKIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSVNDKG 548
EKI +G V+RE +F KLW H V PTL+ +L L+LDYVDLY++ P++
Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 129
Query: 549 EDLAIDH-----------LDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KP 689
E D TW+ ME + GL K++GVSNFN QLE +L + + KP
Sbjct: 130 EIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKP 189
Query: 690 VVNQVEINPTLTQHKLVRFCXERSVV 767
V NQVE +P TQ KL++FC + +V
Sbjct: 190 VSNQVECHPYFTQPKLLKFCQQHDIV 215
>BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 170 bits (413), Expect = 5e-42
Identities = 95/206 (46%), Positives = 124/206 (60%), Gaps = 15/206 (7%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYAR-KPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAIS 368
I LS+G +PI+GLGTY+ K P G SV+ AID GYRHID A +Y+NE EVGEAI
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIR 69
Query: 369 EKIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSVNDKG 548
EKI +G V+RE +F KLW H V PTL+ +L L+LDYVDLY++ P++
Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 129
Query: 549 EDLAIDH-----------LDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KP 689
E D TW+ ME + GL K++GVSNFN QLE +L + + KP
Sbjct: 130 EIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKP 189
Query: 690 VVNQVEINPTLTQHKLVRFCXERSVV 767
V NQVE +P TQ KL++FC + +V
Sbjct: 190 VSNQVECHPYFTQPKLLKFCQQHDIV 215
>AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductase
protein.
Length = 326
Score = 170 bits (413), Expect = 5e-42
Identities = 95/206 (46%), Positives = 124/206 (60%), Gaps = 15/206 (7%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYAR-KPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAIS 368
I LS+G +PI+GLGTY+ K P G SV+ AID GYRHID A +Y+NE EVGEAI
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIR 69
Query: 369 EKIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSVNDKG 548
EKI +G V+RE +F KLW H V PTL+ +L L+LDYVDLY++ P++
Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 129
Query: 549 EDLAIDH-----------LDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KP 689
E D TW+ ME + GL K++GVSNFN QLE +L + + KP
Sbjct: 130 EIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKP 189
Query: 690 VVNQVEINPTLTQHKLVRFCXERSVV 767
V NQVE +P TQ KL++FC + +V
Sbjct: 190 VSNQVECHPYFTQPKLLKFCQQHDIV 215
>BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 168 bits (408), Expect = 2e-41
Identities = 93/207 (44%), Positives = 129/207 (62%), Gaps = 14/207 (6%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISE 371
++L++G MP+LG GTYA P + + + AI+AG+RHID+A +Y NE +VG AI
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 372 KIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV----- 536
KI G VKRE +F T+KLW V P L+ SL KL+LDYVDLYL+H+P+++
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 537 ---NDKGEDLAIDHLD---TWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPV 692
D+ + D +D TW+ ME+ + GL K+IGVSNFN QLE +L + + KPV
Sbjct: 128 PLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNYRQLEMILNKPGLKYKPV 187
Query: 693 VNQVEINPTLTQHKLVRFCXERSVVPV 773
NQVE +P L Q KL+ FC + +V V
Sbjct: 188 CNQVECHPYLNQSKLLDFCKSKDIVLV 214
>D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase
isoform DD1 protein.
Length = 306
Score = 167 bits (407), Expect = 3e-41
Identities = 91/197 (46%), Positives = 122/197 (61%), Gaps = 14/197 (7%)
Frame = +3
Query: 225 ILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEKIDQGVVKRE 401
+LG GTYA P + L + + AI+AG+RHID+A +Y NE +VG AI KI G VKRE
Sbjct: 1 VLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKRE 60
Query: 402 QLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV--------NDKGEDL 557
+F T+KLW + H V P L+ SL L+LDYVDLYL+H+PVSV D+ +
Sbjct: 61 DIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKI 120
Query: 558 AIDHLD---TWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPVVNQVEINPTL 722
D +D TW+ +E+ + GL K+IGVSNFN QLE +L + + KPV NQVE +P
Sbjct: 121 LFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYF 180
Query: 723 TQHKLVRFCXERSVVPV 773
Q KL+ FC + +V V
Sbjct: 181 NQRKLLDFCKSKDIVLV 197
>S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase
protein.
Length = 323
Score = 167 bits (406), Expect = 4e-41
Identities = 93/207 (44%), Positives = 129/207 (62%), Gaps = 14/207 (6%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISE 371
++L++G MP+LG GTYA P + + + AI+AG+RHID+A +Y NE +VG AI
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 372 KIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV----- 536
KI G VKRE +F T+KLW V P L+ SL KL+LDYVDLYL+H+P+++
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 537 ---NDKGEDLAIDHLD---TWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPV 692
D+ + D +D TW+ ME+ + GL K+IGVSNFN QLE +L + + KPV
Sbjct: 128 PLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPV 187
Query: 693 VNQVEINPTLTQHKLVRFCXERSVVPV 773
NQVE +P L Q KL+ FC + +V V
Sbjct: 188 CNQVECHPYLNQSKLLDFCKSKDIVLV 214
>D26125-1|BAA05122.1| 321|Homo sapiens 3
alpha-hydroxysteroid/dihydrodiol dehydrogenase DD4
protein.
Length = 321
Score = 167 bits (406), Expect = 4e-41
Identities = 93/207 (44%), Positives = 129/207 (62%), Gaps = 14/207 (6%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISE 371
++L++G MP+LG GTYA P + + + AI+AG+RHID+A +Y NE +VG AI
Sbjct: 6 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 65
Query: 372 KIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV----- 536
KI G VKRE +F T+KLW V P L+ SL KL+LDYVDLYL+H+P+++
Sbjct: 66 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 125
Query: 537 ---NDKGEDLAIDHLD---TWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPV 692
D+ + D +D TW+ ME+ + GL K+IGVSNFN QLE +L + + KPV
Sbjct: 126 PLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPV 185
Query: 693 VNQVEINPTLTQHKLVRFCXERSVVPV 773
NQVE +P L Q KL+ FC + +V V
Sbjct: 186 CNQVECHPYLNQSKLLDFCKSKDIVLV 212
>AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 167 bits (406), Expect = 4e-41
Identities = 93/207 (44%), Positives = 129/207 (62%), Gaps = 14/207 (6%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISE 371
++L++G MP+LG GTYA P + + + AI+AG+RHID+A +Y NE +VG AI
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 372 KIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV----- 536
KI G VKRE +F T+KLW V P L+ SL KL+LDYVDLYL+H+P+++
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 537 ---NDKGEDLAIDHLD---TWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPV 692
D+ + D +D TW+ ME+ + GL K+IGVSNFN QLE +L + + KPV
Sbjct: 128 PLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPV 187
Query: 693 VNQVEINPTLTQHKLVRFCXERSVVPV 773
NQVE +P L Q KL+ FC + +V V
Sbjct: 188 CNQVECHPYLNQSKLLDFCKSKDIVLV 214
>AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 167 bits (406), Expect = 4e-41
Identities = 93/207 (44%), Positives = 129/207 (62%), Gaps = 14/207 (6%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISE 371
++L++G MP+LG GTYA P + + + AI+AG+RHID+A +Y NE +VG AI
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 372 KIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV----- 536
KI G VKRE +F T+KLW V P L+ SL KL+LDYVDLYL+H+P+++
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 537 ---NDKGEDLAIDHLD---TWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPV 692
D+ + D +D TW+ ME+ + GL K+IGVSNFN QLE +L + + KPV
Sbjct: 128 PLPKDENGKVIFDTVDLCATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPV 187
Query: 693 VNQVEINPTLTQHKLVRFCXERSVVPV 773
NQVE +P L Q KL+ FC + +V V
Sbjct: 188 CNQVECHPYLNQSKLLDFCKSKDIVLV 214
>AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 167 bits (406), Expect = 4e-41
Identities = 93/207 (44%), Positives = 129/207 (62%), Gaps = 14/207 (6%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISE 371
++L++G MP+LG GTYA P + + + AI+AG+RHID+A +Y NE +VG AI
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 372 KIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV----- 536
KI G VKRE +F T+KLW V P L+ SL KL+LDYVDLYL+H+P+++
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 537 ---NDKGEDLAIDHLD---TWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPV 692
D+ + D +D TW+ ME+ + GL K+IGVSNFN QLE +L + + KPV
Sbjct: 128 PLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPV 187
Query: 693 VNQVEINPTLTQHKLVRFCXERSVVPV 773
NQVE +P L Q KL+ FC + +V V
Sbjct: 188 CNQVECHPYLNQSKLLDFCKSKDIVLV 214
>AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 167 bits (406), Expect = 4e-41
Identities = 93/207 (44%), Positives = 129/207 (62%), Gaps = 14/207 (6%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISE 371
++L++G MP+LG GTYA P + + + AI+AG+RHID+A +Y NE +VG AI
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 372 KIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV----- 536
KI G VKRE +F T+KLW V P L+ SL KL+LDYVDLYL+H+P+++
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 537 ---NDKGEDLAIDHLD---TWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPV 692
D+ + D +D TW+ ME+ + GL K+IGVSNFN QLE +L + + KPV
Sbjct: 128 PLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPV 187
Query: 693 VNQVEINPTLTQHKLVRFCXERSVVPV 773
NQVE +P L Q KL+ FC + +V V
Sbjct: 188 CNQVECHPYLNQSKLLDFCKSKDIVLV 214
>M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordecone
reductase mRNA, complete cds. ).
Length = 308
Score = 162 bits (393), Expect = 1e-39
Identities = 91/199 (45%), Positives = 123/199 (61%), Gaps = 14/199 (7%)
Frame = +3
Query: 219 MPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEKIDQGVVK 395
MP+LG GTYA P + + + AI+AG+RHID+A +Y NE +VG AI KI G VK
Sbjct: 1 MPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVK 60
Query: 396 REQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV--------NDKGE 551
RE +F T+KLW V P L+ SL KL+LDYVDLYL+H+P+++ D+
Sbjct: 61 REDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENG 120
Query: 552 DLAIDHLD---TWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPVVNQVEINP 716
+ D +D TW+ ME+ + GL K+IGVSNFN QLE +L + + KPV NQVE +P
Sbjct: 121 KVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHP 180
Query: 717 TLTQHKLVRFCXERSVVPV 773
L Q KL+ FC + +V V
Sbjct: 181 YLNQSKLLDFCKSKDIVLV 199
>BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein.
Length = 307
Score = 161 bits (390), Expect = 3e-39
Identities = 93/215 (43%), Positives = 125/215 (58%), Gaps = 32/215 (14%)
Frame = +3
Query: 216 DMPILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEKIDQGVVK 395
D+P +GL ++ K PG+V +V+ AIDAGYRH D A Y NE EVG I KI +G V+
Sbjct: 3 DIPAVGLSSW--KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVR 60
Query: 396 REQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV------------- 536
RE LF+ TKLW H +S V ++SL L+L+Y+DLYL+HWP+
Sbjct: 61 REDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSE 120
Query: 537 ------NDKGEDLAIDH-----------LDTWKGMEEVLELGLTKAIGVSNFNEEQLERL 665
+ + +DL +D LDTW+ ME+++ GL K IGVSNFN EQLERL
Sbjct: 121 LSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERL 180
Query: 666 LREATV--KPVVNQVEINPTLTQHKLVRFCXERSV 764
L + + KP+ NQ+E +P LTQ L+ FC R V
Sbjct: 181 LNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDV 215
>AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase
loopADR protein.
Length = 320
Score = 161 bits (390), Expect = 3e-39
Identities = 93/215 (43%), Positives = 125/215 (58%), Gaps = 32/215 (14%)
Frame = +3
Query: 216 DMPILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEKIDQGVVK 395
D+P +GL ++ K PG+V +V+ AIDAGYRH D A Y NE EVG I KI +G V+
Sbjct: 3 DIPAVGLSSW--KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVR 60
Query: 396 REQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV------------- 536
RE LF+ TKLW H +S V ++SL L+L+Y+DLYL+HWP+
Sbjct: 61 REDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSE 120
Query: 537 ------NDKGEDLAIDH-----------LDTWKGMEEVLELGLTKAIGVSNFNEEQLERL 665
+ + +DL +D LDTW+ ME+++ GL K IGVSNFN EQLERL
Sbjct: 121 LSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERL 180
Query: 666 LREATV--KPVVNQVEINPTLTQHKLVRFCXERSV 764
L + + KP+ NQ+E +P LTQ L+ FC R V
Sbjct: 181 LNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDV 215
>AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase
related protein 4 protein.
Length = 307
Score = 161 bits (390), Expect = 3e-39
Identities = 93/215 (43%), Positives = 125/215 (58%), Gaps = 32/215 (14%)
Frame = +3
Query: 216 DMPILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEKIDQGVVK 395
D+P +GL ++ K PG+V +V+ AIDAGYRH D A Y NE EVG I KI +G V+
Sbjct: 3 DIPAVGLSSW--KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVR 60
Query: 396 REQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV------------- 536
RE LF+ TKLW H +S V ++SL L+L+Y+DLYL+HWP+
Sbjct: 61 REDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSE 120
Query: 537 ------NDKGEDLAIDH-----------LDTWKGMEEVLELGLTKAIGVSNFNEEQLERL 665
+ + +DL +D LDTW+ ME+++ GL K IGVSNFN EQLERL
Sbjct: 121 LSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERL 180
Query: 666 LREATV--KPVVNQVEINPTLTQHKLVRFCXERSV 764
L + + KP+ NQ+E +P LTQ L+ FC R V
Sbjct: 181 LNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDV 215
>AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase
related protein 2 protein.
Length = 263
Score = 141 bits (341), Expect = 3e-33
Identities = 85/207 (41%), Positives = 119/207 (57%), Gaps = 32/207 (15%)
Frame = +3
Query: 216 DMPILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEKIDQGVVK 395
D+P +GL ++ K PG+V +V+ AIDAGYRH D A Y NE EVG I KI +G V+
Sbjct: 3 DIPAVGLSSW--KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVR 60
Query: 396 REQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV------------- 536
RE LF+ TKLW H +S V ++SL L+L+Y+DLYL+HWP+
Sbjct: 61 REDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSE 120
Query: 537 ------NDKGEDLAIDH-----------LDTWKGMEEVLELGLTKAIGVSNFNEEQLERL 665
+ + +DL +D LDTW+ ME+++ GL K IGVSNFN EQLERL
Sbjct: 121 LSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERL 180
Query: 666 LREATV--KPVVNQVEINPTLTQHKLV 740
L + + KP+ NQ+ I + ++ +V
Sbjct: 181 LNKPGLRFKPLTNQILIRFQIQRNVIV 207
>AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase
related protein 1 protein.
Length = 250
Score = 141 bits (341), Expect = 3e-33
Identities = 85/207 (41%), Positives = 119/207 (57%), Gaps = 32/207 (15%)
Frame = +3
Query: 216 DMPILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEKIDQGVVK 395
D+P +GL ++ K PG+V +V+ AIDAGYRH D A Y NE EVG I KI +G V+
Sbjct: 3 DIPAVGLSSW--KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVR 60
Query: 396 REQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV------------- 536
RE LF+ TKLW H +S V ++SL L+L+Y+DLYL+HWP+
Sbjct: 61 REDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSE 120
Query: 537 ------NDKGEDLAIDH-----------LDTWKGMEEVLELGLTKAIGVSNFNEEQLERL 665
+ + +DL +D LDTW+ ME+++ GL K IGVSNFN EQLERL
Sbjct: 121 LSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERL 180
Query: 666 LREATV--KPVVNQVEINPTLTQHKLV 740
L + + KP+ NQ+ I + ++ +V
Sbjct: 181 LNKPGLRFKPLTNQILIRFQIQRNVIV 207
>AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydela) protein.
Length = 147
Score = 136 bits (330), Expect = 6e-32
Identities = 63/121 (52%), Positives = 89/121 (73%), Gaps = 1/121 (0%)
Frame = +3
Query: 195 IKLSNGQDMPILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEK 374
+ L GQ MP++GLGT+ K EPGQV +V++A+ GYRHID A +Y NE E+GEA+ E
Sbjct: 6 VLLHTGQKMPLIGLGTW--KSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKED 63
Query: 375 IDQG-VVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSVNDKGE 551
+ G V RE+LFVT+KLWN KH DV P L+++LA L+L+Y+DLYL+HWP + ++G+
Sbjct: 64 VGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAF-ERGD 122
Query: 552 D 554
+
Sbjct: 123 N 123
>AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 132 bits (320), Expect = 1e-30
Identities = 82/198 (41%), Positives = 114/198 (57%), Gaps = 4/198 (2%)
Frame = +3
Query: 192 SIKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAIS 368
S++L++G MP+LG GTYA P Q + + AID G+RHID+A +Y+NE EVG+AI
Sbjct: 10 SVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIW 69
Query: 369 EKIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSVNDKG 548
EKI G VKRE++F T KLW V P L+ SL KL DYVDL+++H P ++ G
Sbjct: 70 EKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMKQPG 129
Query: 549 EDLAIDHLDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPVVNQ-VEINPT 719
++L L E +LE V + +LE +L + + KP NQ VE +P
Sbjct: 130 KEL----LPKDASGEIILET-------VELCDTWELELILNKPGLRYKPTCNQVVECHPY 178
Query: 720 LTQHKLVRFCXERSVVPV 773
L Q KL+ FC + +V V
Sbjct: 179 LNQSKLLEFCKSKDIVLV 196
>AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 132 bits (320), Expect = 1e-30
Identities = 82/198 (41%), Positives = 114/198 (57%), Gaps = 4/198 (2%)
Frame = +3
Query: 192 SIKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAIS 368
S++L++G MP+LG GTYA P Q + + AID G+RHID+A +Y+NE EVG+AI
Sbjct: 10 SVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIW 69
Query: 369 EKIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSVNDKG 548
EKI G VKRE++F T KLW V P L+ SL KL DYVDL+++H P ++ G
Sbjct: 70 EKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMKQPG 129
Query: 549 EDLAIDHLDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPVVNQ-VEINPT 719
++L L E +LE V + +LE +L + + KP NQ VE +P
Sbjct: 130 KEL----LPKDASGEIILET-------VELCDTWELELILNKPGLRYKPTCNQVVECHPY 178
Query: 720 LTQHKLVRFCXERSVVPV 773
L Q KL+ FC + +V V
Sbjct: 179 LNQSKLLEFCKSKDIVLV 196
>AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 247
Score = 131 bits (316), Expect = 3e-30
Identities = 73/156 (46%), Positives = 95/156 (60%), Gaps = 13/156 (8%)
Frame = +3
Query: 345 AEVGEAISEKIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHW 524
AEVG AI KI G VKRE +F T+KLW + H V P L+ SL L+LDYVDLYL+H+
Sbjct: 25 AEVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHF 84
Query: 525 PVSV--------NDKGEDLAIDHLD---TWKGMEEVLELGLTKAIGVSNFNEEQLERLLR 671
PVSV D+ + D +D TW+ +E+ + GL K+IGVSNFN QLE +L
Sbjct: 85 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILN 144
Query: 672 EATV--KPVVNQVEINPTLTQHKLVRFCXERSVVPV 773
+ + KPV NQVE +P Q KL+ FC + +V V
Sbjct: 145 KPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLV 180
>BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 115 bits (277), Expect = 2e-25
Identities = 57/116 (49%), Positives = 77/116 (66%), Gaps = 1/116 (0%)
Frame = +3
Query: 192 SIKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAIS 368
S++L++G MP+LG GTYA P Q + + AID G+RHID+A +Y+NE EVG+AI
Sbjct: 10 SVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIW 69
Query: 369 EKIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV 536
EKI G VKRE++F T KLW V P L+ SL KL DYVDL+++H P ++
Sbjct: 70 EKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAM 125
>BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 115 bits (277), Expect = 2e-25
Identities = 57/116 (49%), Positives = 77/116 (66%), Gaps = 1/116 (0%)
Frame = +3
Query: 192 SIKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAIS 368
S++L++G MP+LG GTYA P Q + + AID G+RHID+A +Y+NE EVG+AI
Sbjct: 10 SVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIW 69
Query: 369 EKIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV 536
EKI G VKRE++F T KLW V P L+ SL KL DYVDL+++H P ++
Sbjct: 70 EKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAM 125
>AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens
cDNA FLJ16347 fis, clone TESTI2036288, moderately
similar to PROSTAGLANDIN-F SYNTHASE 1 (EC 1.1.1.188). ).
Length = 129
Score = 115 bits (277), Expect = 2e-25
Identities = 57/116 (49%), Positives = 77/116 (66%), Gaps = 1/116 (0%)
Frame = +3
Query: 192 SIKLSNGQDMPILGLGTYARKPEP-GQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAIS 368
S++L++G MP+LG GTYA P Q + + AID G+RHID+A +Y+NE EVG+AI
Sbjct: 10 SVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIW 69
Query: 369 EKIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPVSV 536
EKI G VKRE++F T KLW V P L+ SL KL DYVDL+++H P ++
Sbjct: 70 EKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAM 125
>AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase
related protein 3 protein.
Length = 222
Score = 111 bits (268), Expect = 2e-24
Identities = 53/105 (50%), Positives = 71/105 (67%)
Frame = +3
Query: 216 DMPILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEKIDQGVVK 395
D+P +GL ++ K PG+V +V+ AIDAGYRH D A Y NE EVG I KI +G V+
Sbjct: 3 DIPAVGLSSW--KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVR 60
Query: 396 REQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPV 530
RE LF+ TKLW H +S V ++SL L+L+Y+DLYL+HWP+
Sbjct: 61 REDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPM 105
>AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto
reductase protein.
Length = 130
Score = 108 bits (260), Expect = 2e-23
Identities = 57/114 (50%), Positives = 75/114 (65%), Gaps = 1/114 (0%)
Frame = +3
Query: 192 SIKLSNGQDMPILGLGT-YARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAIS 368
S+KL++G+ MPILG GT ARK V +V+ AID GYRHID+A + NE +G+AI
Sbjct: 8 SVKLNDGKFMPILGFGTSVARKVAMSNVEEAVQVAIDVGYRHIDSAYTHLNEEGIGQAIR 67
Query: 369 EKIDQGVVKREQLFVTTKLWNDKHARSDVLPTLKESLAKLRLDYVDLYLVHWPV 530
+KI G VKR+ +F TTK+W V L+ SL KL+L Y+DLYL H+PV
Sbjct: 68 KKIANGTVKRKDIFYTTKVWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPV 121
>AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens
cDNA FLJ25413 fis, clone TST03402, highly similar to
3-OXO-5-BETA-STEROID 4-DEHYDROGENASE (EC 1.3.99.6). ).
Length = 146
Score = 68.5 bits (160), Expect = 2e-11
Identities = 32/66 (48%), Positives = 44/66 (66%), Gaps = 2/66 (3%)
Frame = +3
Query: 576 TWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPVVNQVEINPTLTQHKLVRFC 749
TW+ ME + GL K++GVSNFN QLE +L + + KPV NQVE +P TQ KL++FC
Sbjct: 28 TWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFC 87
Query: 750 XERSVV 767
+ +V
Sbjct: 88 QQHDIV 93
>AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthase
protein.
Length = 67
Score = 50.0 bits (114), Expect = 9e-06
Identities = 27/61 (44%), Positives = 35/61 (57%), Gaps = 2/61 (3%)
Frame = +3
Query: 525 PVSVNDKGEDLAIDHLDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATV--KPVVN 698
P N K +D TW+ ME+ + GL K+IGVSNFN QLE +L + + KPV N
Sbjct: 7 PTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCN 66
Query: 699 Q 701
Q
Sbjct: 67 Q 67
>L35546-1|AAA65028.1| 274|Homo sapiens gamma-glutamylcysteine
synthetase light subunit protein.
Length = 274
Score = 47.6 bits (108), Expect = 5e-05
Identities = 37/125 (29%), Positives = 70/125 (56%), Gaps = 2/125 (1%)
Frame = +3
Query: 342 EAEVGEAISEKIDQGVVKREQLFVTTKLWN-DKHARSDVLPTLKESLAKLRLDYVDLYLV 518
E V A+ EKI+ +RE++ V+ KL+ + ++ S + + + L + +D ++
Sbjct: 71 ECTVSHAV-EKINPD--EREEMKVSAKLFIVESNSSSSTRSAVDMACSVLGVAQLDSVII 127
Query: 519 HWPVSVNDKGEDLAIDHLDT-WKGMEEVLELGLTKAIGVSNFNEEQLERLLREATVKPVV 695
P + D G +L+++HL W+ +E +++ AIG S+ ++ QLE+L + A VKP
Sbjct: 128 ASP-PIED-GVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNS 185
Query: 696 NQVEI 710
NQV +
Sbjct: 186 NQVNL 190
>CR541833-1|CAG46632.1| 274|Homo sapiens GCLM protein.
Length = 274
Score = 47.6 bits (108), Expect = 5e-05
Identities = 37/125 (29%), Positives = 70/125 (56%), Gaps = 2/125 (1%)
Frame = +3
Query: 342 EAEVGEAISEKIDQGVVKREQLFVTTKLWN-DKHARSDVLPTLKESLAKLRLDYVDLYLV 518
E V A+ EKI+ +RE++ V+ KL+ + ++ S + + + L + +D ++
Sbjct: 71 ECTVSHAV-EKINPD--EREEMKVSAKLFIVESNSSSSTRSAVDMACSVLGVAQLDSVII 127
Query: 519 HWPVSVNDKGEDLAIDHLDT-WKGMEEVLELGLTKAIGVSNFNEEQLERLLREATVKPVV 695
P + D G +L+++HL W+ +E +++ AIG S+ ++ QLE+L + A VKP
Sbjct: 128 ASP-PIED-GVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNS 185
Query: 696 NQVEI 710
NQV +
Sbjct: 186 NQVNL 190
>BC041809-1|AAH41809.1| 274|Homo sapiens glutamate-cysteine ligase,
modifier subunit protein.
Length = 274
Score = 47.6 bits (108), Expect = 5e-05
Identities = 37/125 (29%), Positives = 70/125 (56%), Gaps = 2/125 (1%)
Frame = +3
Query: 342 EAEVGEAISEKIDQGVVKREQLFVTTKLWN-DKHARSDVLPTLKESLAKLRLDYVDLYLV 518
E V A+ EKI+ +RE++ V+ KL+ + ++ S + + + L + +D ++
Sbjct: 71 ECTVSHAV-EKINPD--EREEMKVSAKLFIVESNSSSSTRSAVDMACSVLGVAQLDSVII 127
Query: 519 HWPVSVNDKGEDLAIDHLDT-WKGMEEVLELGLTKAIGVSNFNEEQLERLLREATVKPVV 695
P + D G +L+++HL W+ +E +++ AIG S+ ++ QLE+L + A VKP
Sbjct: 128 ASP-PIED-GVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNS 185
Query: 696 NQVEI 710
NQV +
Sbjct: 186 NQVNL 190
>AY773965-1|AAV28733.1| 274|Homo sapiens glutamate-cysteine ligase,
modifier subunit protein.
Length = 274
Score = 47.6 bits (108), Expect = 5e-05
Identities = 37/125 (29%), Positives = 70/125 (56%), Gaps = 2/125 (1%)
Frame = +3
Query: 342 EAEVGEAISEKIDQGVVKREQLFVTTKLWN-DKHARSDVLPTLKESLAKLRLDYVDLYLV 518
E V A+ EKI+ +RE++ V+ KL+ + ++ S + + + L + +D ++
Sbjct: 71 ECTVSHAV-EKINPD--EREEMKVSAKLFIVESNSSSSTRSAVDMACSVLGVAQLDSVII 127
Query: 519 HWPVSVNDKGEDLAIDHLDT-WKGMEEVLELGLTKAIGVSNFNEEQLERLLREATVKPVV 695
P + D G +L+++HL W+ +E +++ AIG S+ ++ QLE+L + A VKP
Sbjct: 128 ASP-PIED-GVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNS 185
Query: 696 NQVEI 710
NQV +
Sbjct: 186 NQVNL 190
>AL117351-10|CAI22976.1| 274|Homo sapiens glutamate-cysteine
ligase, modifier subunit protein.
Length = 274
Score = 47.6 bits (108), Expect = 5e-05
Identities = 37/125 (29%), Positives = 70/125 (56%), Gaps = 2/125 (1%)
Frame = +3
Query: 342 EAEVGEAISEKIDQGVVKREQLFVTTKLWN-DKHARSDVLPTLKESLAKLRLDYVDLYLV 518
E V A+ EKI+ +RE++ V+ KL+ + ++ S + + + L + +D ++
Sbjct: 71 ECTVSHAV-EKINPD--EREEMKVSAKLFIVESNSSSSTRSAVDMACSVLGVAQLDSVII 127
Query: 519 HWPVSVNDKGEDLAIDHLDT-WKGMEEVLELGLTKAIGVSNFNEEQLERLLREATVKPVV 695
P + D G +L+++HL W+ +E +++ AIG S+ ++ QLE+L + A VKP
Sbjct: 128 ASP-PIED-GVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNS 185
Query: 696 NQVEI 710
NQV +
Sbjct: 186 NQVNL 190
>AL049796-2|CAI21813.1| 274|Homo sapiens glutamate-cysteine ligase,
modifier subunit protein.
Length = 274
Score = 47.6 bits (108), Expect = 5e-05
Identities = 37/125 (29%), Positives = 70/125 (56%), Gaps = 2/125 (1%)
Frame = +3
Query: 342 EAEVGEAISEKIDQGVVKREQLFVTTKLWN-DKHARSDVLPTLKESLAKLRLDYVDLYLV 518
E V A+ EKI+ +RE++ V+ KL+ + ++ S + + + L + +D ++
Sbjct: 71 ECTVSHAV-EKINPD--EREEMKVSAKLFIVESNSSSSTRSAVDMACSVLGVAQLDSVII 127
Query: 519 HWPVSVNDKGEDLAIDHLDT-WKGMEEVLELGLTKAIGVSNFNEEQLERLLREATVKPVV 695
P + D G +L+++HL W+ +E +++ AIG S+ ++ QLE+L + A VKP
Sbjct: 128 ASP-PIED-GVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNS 185
Query: 696 NQVEI 710
NQV +
Sbjct: 186 NQVNL 190
>AF026947-1|AAC52104.1| 330|Homo sapiens aflatoxin aldehyde
reductase AFAR protein.
Length = 330
Score = 33.9 bits (74), Expect = 0.65
Identities = 28/105 (26%), Positives = 51/105 (48%), Gaps = 4/105 (3%)
Frame = +3
Query: 225 ILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEKIDQGVVKRE- 401
+LG R+ + +VR ++ G+ +DTA +Y + E I + G+ +
Sbjct: 12 VLGTMEMGRRMDAPASAAAVRAFLERGHTELDTAFMYSDGQS--ETILGGLGLGLGGGDC 69
Query: 402 QLFVTTKL--WNDKHARSD-VLPTLKESLAKLRLDYVDLYLVHWP 527
++ + TK W+ K + D V L+ SL +L+ VDL+ +H P
Sbjct: 70 RVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHTP 114
>Y16675-1|CAA76347.1| 330|Homo sapiens aflatoxin B1-aldehyde
reductase protein.
Length = 330
Score = 33.5 bits (73), Expect = 0.86
Identities = 28/105 (26%), Positives = 51/105 (48%), Gaps = 4/105 (3%)
Frame = +3
Query: 225 ILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEKIDQGVVKRE- 401
+LG R+ + +VR ++ G+ +DTA +Y + E I + G+ +
Sbjct: 12 VLGTMEMGRRMDAPASAAAVRAFLERGHTELDTAFMYSDGQ--SETILGGLGLGLGGGDC 69
Query: 402 QLFVTTKL--WNDKHARSD-VLPTLKESLAKLRLDYVDLYLVHWP 527
++ + TK W+ K + D V L+ SL +L+ VDL+ +H P
Sbjct: 70 RVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAP 114
>BT007347-1|AAP36011.1| 330|Homo sapiens aldo-keto reductase family
7, member A2 (aflatoxin aldehyde reductase) protein.
Length = 330
Score = 33.5 bits (73), Expect = 0.86
Identities = 28/105 (26%), Positives = 51/105 (48%), Gaps = 4/105 (3%)
Frame = +3
Query: 225 ILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEKIDQGVVKRE- 401
+LG R+ + +VR ++ G+ +DTA +Y + E I + G+ +
Sbjct: 12 VLGTMEMGRRMDAPASAAAVRAFLERGHTELDTAFMYSDGQ--SETILGGLGLGLGGGDC 69
Query: 402 QLFVTTKL--WNDKHARSD-VLPTLKESLAKLRLDYVDLYLVHWP 527
++ + TK W+ K + D V L+ SL +L+ VDL+ +H P
Sbjct: 70 RVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAP 114
>BC013996-1|AAH13996.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 33.5 bits (73), Expect = 0.86
Identities = 28/105 (26%), Positives = 51/105 (48%), Gaps = 4/105 (3%)
Frame = +3
Query: 225 ILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEKIDQGVVKRE- 401
+LG R+ + +VR ++ G+ +DTA +Y + E I + G+ +
Sbjct: 12 VLGTMEMGRRMDAPASAAAVRAFLERGHTELDTAFMYSDGQ--SETILGGLGLGLGGGDC 69
Query: 402 QLFVTTKL--WNDKHARSD-VLPTLKESLAKLRLDYVDLYLVHWP 527
++ + TK W+ K + D V L+ SL +L+ VDL+ +H P
Sbjct: 70 RVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAP 114
>BC012171-1|AAH12171.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 33.5 bits (73), Expect = 0.86
Identities = 28/105 (26%), Positives = 51/105 (48%), Gaps = 4/105 (3%)
Frame = +3
Query: 225 ILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEKIDQGVVKRE- 401
+LG R+ + +VR ++ G+ +DTA +Y + E I + G+ +
Sbjct: 12 VLGTMEMGRRMDAPASAAAVRAFLERGHTELDTAFMYSDGQ--SETILGGLGLGLGGGDC 69
Query: 402 QLFVTTKL--WNDKHARSD-VLPTLKESLAKLRLDYVDLYLVHWP 527
++ + TK W+ K + D V L+ SL +L+ VDL+ +H P
Sbjct: 70 RVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAP 114
>BC011586-1|AAH11586.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 33.5 bits (73), Expect = 0.86
Identities = 28/105 (26%), Positives = 51/105 (48%), Gaps = 4/105 (3%)
Frame = +3
Query: 225 ILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEKIDQGVVKRE- 401
+LG R+ + +VR ++ G+ +DTA +Y + E I + G+ +
Sbjct: 12 VLGTMEMGRRMDAPASAAAVRAFLERGHTELDTAFMYSDGQ--SETILGGLGLGLGGGDC 69
Query: 402 QLFVTTKL--WNDKHARSD-VLPTLKESLAKLRLDYVDLYLVHWP 527
++ + TK W+ K + D V L+ SL +L+ VDL+ +H P
Sbjct: 70 RVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAP 114
>BC010852-1|AAH10852.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 33.5 bits (73), Expect = 0.86
Identities = 28/105 (26%), Positives = 51/105 (48%), Gaps = 4/105 (3%)
Frame = +3
Query: 225 ILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEKIDQGVVKRE- 401
+LG R+ + +VR ++ G+ +DTA +Y + E I + G+ +
Sbjct: 12 VLGTMEMGRRMDAPASAAAVRAFLERGHTELDTAFMYSDGQ--SETILGGLGLGLGGGDC 69
Query: 402 QLFVTTKL--WNDKHARSD-VLPTLKESLAKLRLDYVDLYLVHWP 527
++ + TK W+ K + D V L+ SL +L+ VDL+ +H P
Sbjct: 70 RVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAP 114
>BC007352-1|AAH07352.2| 358|Homo sapiens AKR7A2 protein protein.
Length = 358
Score = 33.5 bits (73), Expect = 0.86
Identities = 28/105 (26%), Positives = 51/105 (48%), Gaps = 4/105 (3%)
Frame = +3
Query: 225 ILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEKIDQGVVKRE- 401
+LG R+ + +VR ++ G+ +DTA +Y + E I + G+ +
Sbjct: 40 VLGTMEMGRRMDAPASAAAVRAFLERGHTELDTAFMYSDGQ--SETILGGLGLGLGGGDC 97
Query: 402 QLFVTTKL--WNDKHARSD-VLPTLKESLAKLRLDYVDLYLVHWP 527
++ + TK W+ K + D V L+ SL +L+ VDL+ +H P
Sbjct: 98 RVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAP 142
>BC004111-1|AAH04111.3| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 33.5 bits (73), Expect = 0.86
Identities = 28/105 (26%), Positives = 51/105 (48%), Gaps = 4/105 (3%)
Frame = +3
Query: 225 ILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEKIDQGVVKRE- 401
+LG R+ + +VR ++ G+ +DTA +Y + E I + G+ +
Sbjct: 12 VLGTMEMGRRMDAPASAAAVRAFLERGHTELDTAFMYSDGQ--SETILGGLGLGLGGGDC 69
Query: 402 QLFVTTKL--WNDKHARSD-VLPTLKESLAKLRLDYVDLYLVHWP 527
++ + TK W+ K + D V L+ SL +L+ VDL+ +H P
Sbjct: 70 RVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAP 114
>AL035413-8|CAB72321.1| 330|Homo sapiens aldo-keto reductase family
7, member A2 (aflatoxin aldehyde reductase) protein.
Length = 330
Score = 33.5 bits (73), Expect = 0.86
Identities = 28/105 (26%), Positives = 51/105 (48%), Gaps = 4/105 (3%)
Frame = +3
Query: 225 ILGLGTYARKPEPGQVLNSVRWAIDAGYRHIDTATVYKNEAEVGEAISEKIDQGVVKRE- 401
+LG R+ + +VR ++ G+ +DTA +Y + E I + G+ +
Sbjct: 12 VLGTMEMGRRMDAPASAAAVRAFLERGHTELDTAFMYSDGQ--SETILGGLGLGLGGGDC 69
Query: 402 QLFVTTKL--WNDKHARSD-VLPTLKESLAKLRLDYVDLYLVHWP 527
++ + TK W+ K + D V L+ SL +L+ VDL+ +H P
Sbjct: 70 RVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAP 114
>AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto
reductase protein.
Length = 45
Score = 33.1 bits (72), Expect = 1.1
Identities = 14/22 (63%), Positives = 18/22 (81%)
Frame = +3
Query: 465 LKESLAKLRLDYVDLYLVHWPV 530
L+ SL KL+L Y+DLYL H+PV
Sbjct: 15 LEMSLKKLQLSYMDLYLFHFPV 36
>AY368652-1|AAQ72693.1| 135|Homo sapiens multiple myeloma
susceptibility tumor suppressor protein protein.
Length = 135
Score = 31.5 bits (68), Expect = 3.5
Identities = 23/82 (28%), Positives = 41/82 (50%), Gaps = 3/82 (3%)
Frame = +3
Query: 438 HARSDVLPTL--KESLAKLRLDYVDLYLVHWPVSVNDKGEDLAIDHLDTWKGMEEV-LEL 608
H S + P L KES+ + +Y VH+ +S+N K +D +++ +D +E +
Sbjct: 28 HCPSKISPELLKKESITNSYAHF-QIYNVHYTMSINGKLQDGSME-IDAGNNLETFKMGS 85
Query: 609 GLTKAIGVSNFNEEQLERLLRE 674
G +AI V++F + RE
Sbjct: 86 GAEEAIAVNDFQNVSIFHAFRE 107
>Y18880-1|CAB56154.1| 715|Homo sapiens midline 2 protein protein.
Length = 715
Score = 30.7 bits (66), Expect = 6.1
Identities = 16/61 (26%), Positives = 34/61 (55%)
Frame = +3
Query: 573 DTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATVKPVVNQVEINPTLTQHKLVRFCX 752
D ++ +++ LE+ LT + ++ E Q+ +L++ + QVE+N + + KL+ C
Sbjct: 214 DRFEKLKQTLEMNLTNLVKRNSELENQMAKLIQ------ICQQVEVNTAMHEAKLMEECD 267
Query: 753 E 755
E
Sbjct: 268 E 268
>BT006663-1|AAP35309.1| 685|Homo sapiens midline 2 protein.
Length = 685
Score = 30.7 bits (66), Expect = 6.1
Identities = 16/61 (26%), Positives = 34/61 (55%)
Frame = +3
Query: 573 DTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATVKPVVNQVEINPTLTQHKLVRFCX 752
D ++ +++ LE+ LT + ++ E Q+ +L++ + QVE+N + + KL+ C
Sbjct: 214 DRFEKLKQTLEMNLTNLVKRNSELENQMAKLIQ------ICQQVEVNTAMHEAKLMEECD 267
Query: 753 E 755
E
Sbjct: 268 E 268
>BC017707-1|AAH17707.1| 685|Homo sapiens midline 2 protein.
Length = 685
Score = 30.7 bits (66), Expect = 6.1
Identities = 16/61 (26%), Positives = 34/61 (55%)
Frame = +3
Query: 573 DTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATVKPVVNQVEINPTLTQHKLVRFCX 752
D ++ +++ LE+ LT + ++ E Q+ +L++ + QVE+N + + KL+ C
Sbjct: 214 DRFEKLKQTLEMNLTNLVKRNSELENQMAKLIQ------ICQQVEVNTAMHEAKLMEECD 267
Query: 753 E 755
E
Sbjct: 268 E 268
>AY625004-1|AAT48105.1| 685|Homo sapiens TRIM1 beta protein.
Length = 685
Score = 30.7 bits (66), Expect = 6.1
Identities = 16/61 (26%), Positives = 34/61 (55%)
Frame = +3
Query: 573 DTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATVKPVVNQVEINPTLTQHKLVRFCX 752
D ++ +++ LE+ LT + ++ E Q+ +L++ + QVE+N + + KL+ C
Sbjct: 214 DRFEKLKQTLEMNLTNLVKRNSELENQMAKLIQ------ICQQVEVNTAMHEAKLMEECD 267
Query: 753 E 755
E
Sbjct: 268 E 268
>AL109946-4|CAO72054.1| 685|Homo sapiens midline 2 protein.
Length = 685
Score = 30.7 bits (66), Expect = 6.1
Identities = 16/61 (26%), Positives = 34/61 (55%)
Frame = +3
Query: 573 DTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATVKPVVNQVEINPTLTQHKLVRFCX 752
D ++ +++ LE+ LT + ++ E Q+ +L++ + QVE+N + + KL+ C
Sbjct: 214 DRFEKLKQTLEMNLTNLVKRNSELENQMAKLIQ------ICQQVEVNTAMHEAKLMEECD 267
Query: 753 E 755
E
Sbjct: 268 E 268
>AL109946-3|CAO72053.1| 715|Homo sapiens midline 2 protein.
Length = 715
Score = 30.7 bits (66), Expect = 6.1
Identities = 16/61 (26%), Positives = 34/61 (55%)
Frame = +3
Query: 573 DTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATVKPVVNQVEINPTLTQHKLVRFCX 752
D ++ +++ LE+ LT + ++ E Q+ +L++ + QVE+N + + KL+ C
Sbjct: 214 DRFEKLKQTLEMNLTNLVKRNSELENQMAKLIQ------ICQQVEVNTAMHEAKLMEECD 267
Query: 753 E 755
E
Sbjct: 268 E 268
>AL034399-3|CAI42074.1| 685|Homo sapiens midline 2 protein.
Length = 685
Score = 30.7 bits (66), Expect = 6.1
Identities = 16/61 (26%), Positives = 34/61 (55%)
Frame = +3
Query: 573 DTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATVKPVVNQVEINPTLTQHKLVRFCX 752
D ++ +++ LE+ LT + ++ E Q+ +L++ + QVE+N + + KL+ C
Sbjct: 214 DRFEKLKQTLEMNLTNLVKRNSELENQMAKLIQ------ICQQVEVNTAMHEAKLMEECD 267
Query: 753 E 755
E
Sbjct: 268 E 268
>AL034399-2|CAI42073.1| 715|Homo sapiens midline 2 protein.
Length = 715
Score = 30.7 bits (66), Expect = 6.1
Identities = 16/61 (26%), Positives = 34/61 (55%)
Frame = +3
Query: 573 DTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATVKPVVNQVEINPTLTQHKLVRFCX 752
D ++ +++ LE+ LT + ++ E Q+ +L++ + QVE+N + + KL+ C
Sbjct: 214 DRFEKLKQTLEMNLTNLVKRNSELENQMAKLIQ------ICQQVEVNTAMHEAKLMEECD 267
Query: 753 E 755
E
Sbjct: 268 E 268
>AF196481-1|AAF07341.1| 685|Homo sapiens RING finger protein
protein.
Length = 685
Score = 30.7 bits (66), Expect = 6.1
Identities = 16/61 (26%), Positives = 34/61 (55%)
Frame = +3
Query: 573 DTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATVKPVVNQVEINPTLTQHKLVRFCX 752
D ++ +++ LE+ LT + ++ E Q+ +L++ + QVE+N + + KL+ C
Sbjct: 214 DRFEKLKQTLEMNLTNLVKRNSELENQMAKLIQ------ICQQVEVNTAMHEAKLMEECD 267
Query: 753 E 755
E
Sbjct: 268 E 268
>J04137-1|AAA35493.1| 538|Homo sapiens protein ( Human 60-kdal
ribonucleoprotein (Ro) mRNA, complete cds. ).
Length = 538
Score = 30.3 bits (65), Expect = 8.0
Identities = 23/65 (35%), Positives = 34/65 (52%)
Frame = +3
Query: 549 EDLAIDHLDTWKGMEEVLELGLTKAIGVSNFNEEQLERLLREATVKPVVNQVEINPTLTQ 728
E LAI KG +EV EL KA+ V E+ L+ L VK +++E+ + +
Sbjct: 193 EGLAIVTKYITKGWKEVHELYKEKALSVET--EKLLKYLEAVEKVKRTKDELEVIHLIEE 250
Query: 729 HKLVR 743
H+LVR
Sbjct: 251 HRLVR 255
>AK128093-1|BAC87272.1| 208|Homo sapiens protein ( Homo sapiens
cDNA FLJ46214 fis, clone TESTI4012623. ).
Length = 208
Score = 30.3 bits (65), Expect = 8.0
Identities = 27/68 (39%), Positives = 29/68 (42%), Gaps = 4/68 (5%)
Frame = -3
Query: 660 SRAAPR*--SWRLLWPS*GPVPGLPPCPSTCRDDRSPDPHL--CR*QTQASAPDTNRRSP 493
S AAPR L WPS P+P PP DRSP P C AS+P RR P
Sbjct: 142 SPAAPRPLPGTSLTWPSRAPLPRPPPRERQGPGDRSPSPSAPSCP-GVGASSP--RRRKP 198
Query: 492 NAVLLRTP 469
TP
Sbjct: 199 REAAGLTP 206
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 115,564,163
Number of Sequences: 237096
Number of extensions: 2470373
Number of successful extensions: 6145
Number of sequences better than 10.0: 121
Number of HSP's better than 10.0 without gapping: 5522
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5893
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9367263024
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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