Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P07_pT_P09
(775 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X66785-1|CAA47285.1| 482|Homo sapiens transacylase protein. 244 3e-64
J03208-1|AAA35589.1| 477|Homo sapiens protein ( Human branched ... 244 3e-64
BT007372-1|AAP36036.1| 482|Homo sapiens dihydrolipoamide branch... 244 3e-64
BC016675-1|AAH16675.1| 482|Homo sapiens dihydrolipoamide branch... 244 3e-64
M27093-1|AAA64512.1| 477|Homo sapiens dihydrolipoyl transacylas... 242 1e-63
AL445928-9|CAH72257.1| 482|Homo sapiens dihydrolipoamide branch... 241 1e-63
L37418-1|AAB59629.1| 453|Homo sapiens dihydrolipoamide succinyl... 109 1e-23
CR456727-1|CAG33008.1| 453|Homo sapiens DLST protein. 109 1e-23
BC001922-1|AAH01922.1| 453|Homo sapiens dihydrolipoamide S-succ... 109 1e-23
BC000302-1|AAH00302.1| 453|Homo sapiens dihydrolipoamide S-succ... 109 1e-23
AC006530-2|AAD30181.1| 453|Homo sapiens alpha-KG-E2 protein. 109 1e-23
D26535-1|BAA05536.1| 453|Homo sapiens dihydrolipoamide succinyl... 108 3e-23
D16373-1|BAA03871.1| 453|Homo sapiens mitochondrial dihydrolipo... 106 1e-22
S72422-1|AAB31066.1| 451|Homo sapiens alpha-ketoglutarate dehyd... 102 1e-21
Y00978-1|CAA68787.1| 615|Homo sapiens PDC-E2 precursor (AA -54 ... 95 3e-19
BC039084-1|AAH39084.1| 647|Homo sapiens dihydrolipoamide S-acet... 95 3e-19
AK223596-1|BAD97316.1| 647|Homo sapiens dihydrolipoamide S-acet... 94 6e-19
J03866-1|AAA62253.1| 613|Homo sapiens dihydrolipoamide acetyltr... 89 2e-17
Y13145-1|CAA73606.1| 501|Homo sapiens protein X protein. 87 7e-17
U82328-1|AAC39661.1| 501|Homo sapiens pyruvate dehydrogenase co... 87 7e-17
U79296-1|AAB50223.1| 375|Homo sapiens dihyrolipoamide acetyl tr... 87 7e-17
AJ298105-1|CAC18649.1| 501|Homo sapiens lipoyl-containing compo... 87 7e-17
AF001437-1|AAB66315.1| 501|Homo sapiens dihydrolipoamide dehydr... 87 7e-17
BC010389-1|AAH10389.1| 501|Homo sapiens pyruvate dehydrogenase ... 87 9e-17
M19301-1|AAA59200.1| 315|Homo sapiens DBT protein. 75 4e-13
AL445928-10|CAH72258.1| 320|Homo sapiens dihydrolipoamide branc... 75 4e-13
X13822-1|CAA32052.1| 220|Homo sapiens dihydrolipoamide S-acetyl... 61 4e-09
X53416-1|CAA37495.1| 2647|Homo sapiens protein ( Human mRNA for ... 36 0.16
L44140-1|AAA92644.1| 2647|Homo sapiens filamin protein. 36 0.16
BX936346-3|CAI43225.1| 2647|Homo sapiens filamin A, alpha (actin... 36 0.16
BX936346-2|CAI43227.1| 2639|Homo sapiens filamin A, alpha (actin... 36 0.16
BX936346-1|CAI43226.1| 2607|Homo sapiens filamin A, alpha (actin... 36 0.16
BX664723-3|CAI43197.1| 2647|Homo sapiens filamin A, alpha (actin... 36 0.16
BX664723-2|CAI43199.1| 2639|Homo sapiens filamin A, alpha (actin... 36 0.16
BX664723-1|CAI43198.1| 2607|Homo sapiens filamin A, alpha (actin... 36 0.16
AK090427-1|BAC03408.1| 2651|Homo sapiens FLJ00343 protein protein. 36 0.16
AK074048-1|BAB84874.1| 1455|Homo sapiens FLJ00119 protein protein. 36 0.16
AB191260-1|BAD52436.1| 2620|Homo sapiens filamin A protein. 36 0.16
AB191259-1|BAD52435.1| 2612|Homo sapiens filamin A protein. 36 0.16
D83597-1|BAA12019.1| 661|Homo sapiens RP105 protein. 35 0.37
BC109070-1|AAI09071.1| 661|Homo sapiens CD180 molecule protein. 35 0.37
BC109069-1|AAI09070.1| 661|Homo sapiens CD180 molecule protein. 35 0.37
BX641085-1|CAE46040.1| 2422|Homo sapiens hypothetical protein pr... 33 1.5
AF191633-1|AAF72339.1| 2602|Homo sapiens filamin protein. 33 1.5
AF043045-1|AAC33845.1| 2602|Homo sapiens actin-binding protein h... 33 1.5
AF042166-1|AAC39842.1| 2602|Homo sapiens beta-filamin protein. 33 1.5
AB209889-1|BAD93126.1| 1613|Homo sapiens filamin B, beta (actin ... 33 1.5
AB191258-1|BAD52434.1| 2591|Homo sapiens filamin B protein. 33 1.5
>X66785-1|CAA47285.1| 482|Homo sapiens transacylase protein.
Length = 482
Score = 244 bits (597), Expect = 3e-64
Identities = 116/210 (55%), Positives = 155/210 (73%)
Frame = -1
Query: 727 PGSVRAVEIPVTKAQARVELALEDKVVPVTGFQRAMVKSMTEAMKIPHFVFSDEYNVTKL 548
P + + +P+ ++ V +DK P+ GFQ+AMVK+M+ A+KIPHF + DE ++T+L
Sbjct: 229 PPKPKDMTVPILVSKPPVFTG-KDKTEPIKGFQKAMVKTMSAALKIPHFGYCDEIDLTEL 287
Query: 547 VESRAALKKQAEERGIRLTYMPIIIKAASLSLSYLPILNSSLDSSCENLIYKASHNIGVA 368
V+ R LK A RGI+L++MP +KAASL L PILN+S+D +C+N+ YKASHNIG+A
Sbjct: 288 VKLREELKPIAFARGIKLSFMPFFLKAASLGLLQFPILNASVDENCQNITYKASHNIGIA 347
Query: 367 MDTPNGLVVPVIKNIQIKSILEIAQELNTLQEKGSKGQLGLNDLTGGTFTISNIGIVGGT 188
MDT GL+VP +KN+QI SI +IA ELN LQ+ GS GQL DLTGGTFT+SNIG +GGT
Sbjct: 348 MDTEQGLIVPNVKNVQICSIFDIATELNRLQKLGSVGQLSTTDLTGGTFTLSNIGSIGGT 407
Query: 187 YTKPVIFPPQVAIGALGKIQVLPRFDSXRE 98
+ KPVI PP+VAIGALG I+ +PRF+ E
Sbjct: 408 FAKPVIMPPEVAIGALGSIKAIPRFNQKGE 437
Score = 55.2 bits (127), Expect = 2e-07
Identities = 24/35 (68%), Positives = 29/35 (82%)
Frame = -2
Query: 105 QGNVVKAHILSVSWSADHRVIDGVTMARFSNXLKN 1
+G V KA I++VSWSADHRVIDG TM+RFSN K+
Sbjct: 435 KGEVYKAQIMNVSWSADHRVIDGATMSRFSNLWKS 469
>J03208-1|AAA35589.1| 477|Homo sapiens protein ( Human branched
chain acyltransferase mRNA, complete cds. ).
Length = 477
Score = 244 bits (597), Expect = 3e-64
Identities = 116/210 (55%), Positives = 155/210 (73%)
Frame = -1
Query: 727 PGSVRAVEIPVTKAQARVELALEDKVVPVTGFQRAMVKSMTEAMKIPHFVFSDEYNVTKL 548
P + + +P+ ++ V +DK P+ GFQ+AMVK+M+ A+KIPHF + DE ++T+L
Sbjct: 224 PPKPKDMTVPILVSKPPVFTG-KDKTEPIKGFQKAMVKTMSAALKIPHFGYCDEIDLTEL 282
Query: 547 VESRAALKKQAEERGIRLTYMPIIIKAASLSLSYLPILNSSLDSSCENLIYKASHNIGVA 368
V+ R LK A RGI+L++MP +KAASL L PILN+S+D +C+N+ YKASHNIG+A
Sbjct: 283 VKLREELKPIAFARGIKLSFMPFFLKAASLGLLQFPILNASVDENCQNITYKASHNIGIA 342
Query: 367 MDTPNGLVVPVIKNIQIKSILEIAQELNTLQEKGSKGQLGLNDLTGGTFTISNIGIVGGT 188
MDT GL+VP +KN+QI SI +IA ELN LQ+ GS GQL DLTGGTFT+SNIG +GGT
Sbjct: 343 MDTEQGLIVPNVKNVQICSIFDIATELNRLQKLGSVGQLSTTDLTGGTFTLSNIGSIGGT 402
Query: 187 YTKPVIFPPQVAIGALGKIQVLPRFDSXRE 98
+ KPVI PP+VAIGALG I+ +PRF+ E
Sbjct: 403 FAKPVIMPPEVAIGALGSIKAIPRFNQKGE 432
Score = 55.2 bits (127), Expect = 2e-07
Identities = 24/35 (68%), Positives = 29/35 (82%)
Frame = -2
Query: 105 QGNVVKAHILSVSWSADHRVIDGVTMARFSNXLKN 1
+G V KA I++VSWSADHRVIDG TM+RFSN K+
Sbjct: 430 KGEVYKAQIMNVSWSADHRVIDGATMSRFSNLWKS 464
>BT007372-1|AAP36036.1| 482|Homo sapiens dihydrolipoamide branched
chain transacylase (E2 component of branched chain ke
protein.
Length = 482
Score = 244 bits (597), Expect = 3e-64
Identities = 116/210 (55%), Positives = 155/210 (73%)
Frame = -1
Query: 727 PGSVRAVEIPVTKAQARVELALEDKVVPVTGFQRAMVKSMTEAMKIPHFVFSDEYNVTKL 548
P + + +P+ ++ V +DK P+ GFQ+AMVK+M+ A+KIPHF + DE ++T+L
Sbjct: 229 PPKPKDMTVPILVSKPPVFTG-KDKTEPIKGFQKAMVKTMSAALKIPHFGYCDEIDLTEL 287
Query: 547 VESRAALKKQAEERGIRLTYMPIIIKAASLSLSYLPILNSSLDSSCENLIYKASHNIGVA 368
V+ R LK A RGI+L++MP +KAASL L PILN+S+D +C+N+ YKASHNIG+A
Sbjct: 288 VKLREELKPIAFARGIKLSFMPFFLKAASLGLLQFPILNASVDENCQNITYKASHNIGIA 347
Query: 367 MDTPNGLVVPVIKNIQIKSILEIAQELNTLQEKGSKGQLGLNDLTGGTFTISNIGIVGGT 188
MDT GL+VP +KN+QI SI +IA ELN LQ+ GS GQL DLTGGTFT+SNIG +GGT
Sbjct: 348 MDTEQGLIVPNVKNVQICSIFDIATELNRLQKLGSVGQLSTTDLTGGTFTLSNIGSIGGT 407
Query: 187 YTKPVIFPPQVAIGALGKIQVLPRFDSXRE 98
+ KPVI PP+VAIGALG I+ +PRF+ E
Sbjct: 408 FAKPVIMPPEVAIGALGSIKAIPRFNQKGE 437
Score = 55.2 bits (127), Expect = 2e-07
Identities = 24/35 (68%), Positives = 29/35 (82%)
Frame = -2
Query: 105 QGNVVKAHILSVSWSADHRVIDGVTMARFSNXLKN 1
+G V KA I++VSWSADHRVIDG TM+RFSN K+
Sbjct: 435 KGEVYKAQIMNVSWSADHRVIDGATMSRFSNLWKS 469
>BC016675-1|AAH16675.1| 482|Homo sapiens dihydrolipoamide branched
chain transacylase E2 protein.
Length = 482
Score = 244 bits (597), Expect = 3e-64
Identities = 116/210 (55%), Positives = 155/210 (73%)
Frame = -1
Query: 727 PGSVRAVEIPVTKAQARVELALEDKVVPVTGFQRAMVKSMTEAMKIPHFVFSDEYNVTKL 548
P + + +P+ ++ V +DK P+ GFQ+AMVK+M+ A+KIPHF + DE ++T+L
Sbjct: 229 PPKPKDMTVPILVSKPPVFTG-KDKTEPIKGFQKAMVKTMSAALKIPHFGYCDEIDLTEL 287
Query: 547 VESRAALKKQAEERGIRLTYMPIIIKAASLSLSYLPILNSSLDSSCENLIYKASHNIGVA 368
V+ R LK A RGI+L++MP +KAASL L PILN+S+D +C+N+ YKASHNIG+A
Sbjct: 288 VKLREELKPIAFARGIKLSFMPFFLKAASLGLLQFPILNASVDENCQNITYKASHNIGIA 347
Query: 367 MDTPNGLVVPVIKNIQIKSILEIAQELNTLQEKGSKGQLGLNDLTGGTFTISNIGIVGGT 188
MDT GL+VP +KN+QI SI +IA ELN LQ+ GS GQL DLTGGTFT+SNIG +GGT
Sbjct: 348 MDTEQGLIVPNVKNVQICSIFDIATELNRLQKLGSVGQLSTTDLTGGTFTLSNIGSIGGT 407
Query: 187 YTKPVIFPPQVAIGALGKIQVLPRFDSXRE 98
+ KPVI PP+VAIGALG I+ +PRF+ E
Sbjct: 408 FAKPVIMPPEVAIGALGSIKAIPRFNQKGE 437
Score = 55.2 bits (127), Expect = 2e-07
Identities = 24/35 (68%), Positives = 29/35 (82%)
Frame = -2
Query: 105 QGNVVKAHILSVSWSADHRVIDGVTMARFSNXLKN 1
+G V KA I++VSWSADHRVIDG TM+RFSN K+
Sbjct: 435 KGEVYKAQIMNVSWSADHRVIDGATMSRFSNLWKS 469
>M27093-1|AAA64512.1| 477|Homo sapiens dihydrolipoyl transacylase
protein.
Length = 477
Score = 242 bits (592), Expect = 1e-63
Identities = 115/210 (54%), Positives = 155/210 (73%)
Frame = -1
Query: 727 PGSVRAVEIPVTKAQARVELALEDKVVPVTGFQRAMVKSMTEAMKIPHFVFSDEYNVTKL 548
P + + +P+ ++ V +DK P+ GFQ+AMVK+M+ A+KIPHF + DE ++T+L
Sbjct: 224 PPKPKDMTVPILVSKPPVFTG-KDKTEPIKGFQKAMVKTMSAALKIPHFGYCDEIDLTEL 282
Query: 547 VESRAALKKQAEERGIRLTYMPIIIKAASLSLSYLPILNSSLDSSCENLIYKASHNIGVA 368
V+ R LK A RGI+L++MP +KAASL L PILN+S+D +C+N+ YKASHNIG+A
Sbjct: 283 VKLREELKPIAFARGIKLSFMPFFLKAASLGLLPFPILNASVDENCQNITYKASHNIGIA 342
Query: 367 MDTPNGLVVPVIKNIQIKSILEIAQELNTLQEKGSKGQLGLNDLTGGTFTISNIGIVGGT 188
MDT G++VP +KN+QI SI +IA ELN LQ+ GS GQL DLTGGTFT+SNIG +GGT
Sbjct: 343 MDTEQGVIVPNVKNVQICSIFDIATELNRLQKLGSVGQLSTTDLTGGTFTLSNIGSIGGT 402
Query: 187 YTKPVIFPPQVAIGALGKIQVLPRFDSXRE 98
+ KPVI PP+VAIGALG I+ +PRF+ E
Sbjct: 403 FAKPVIMPPEVAIGALGSIKAIPRFNQKGE 432
Score = 55.2 bits (127), Expect = 2e-07
Identities = 24/35 (68%), Positives = 29/35 (82%)
Frame = -2
Query: 105 QGNVVKAHILSVSWSADHRVIDGVTMARFSNXLKN 1
+G V KA I++VSWSADHRVIDG TM+RFSN K+
Sbjct: 430 KGEVYKAQIMNVSWSADHRVIDGATMSRFSNLWKS 464
>AL445928-9|CAH72257.1| 482|Homo sapiens dihydrolipoamide branched
chain transacylase E2 protein.
Length = 482
Score = 241 bits (591), Expect = 1e-63
Identities = 115/210 (54%), Positives = 154/210 (73%)
Frame = -1
Query: 727 PGSVRAVEIPVTKAQARVELALEDKVVPVTGFQRAMVKSMTEAMKIPHFVFSDEYNVTKL 548
P + + +P+ ++ V +DK P+ GFQ+AMVK+M+ A+KIPHF + DE ++T+L
Sbjct: 229 PPKPKDMTVPILVSKPPVFTG-KDKTEPIKGFQKAMVKTMSAALKIPHFGYCDEIDLTEL 287
Query: 547 VESRAALKKQAEERGIRLTYMPIIIKAASLSLSYLPILNSSLDSSCENLIYKASHNIGVA 368
V+ R LK A RGI+L++MP +KAASL L PILN+S+D +C+N+ YKASHNIG+A
Sbjct: 288 VKLREELKPIAFARGIKLSFMPFFLKAASLGLLQFPILNASVDENCQNITYKASHNIGIA 347
Query: 367 MDTPNGLVVPVIKNIQIKSILEIAQELNTLQEKGSKGQLGLNDLTGGTFTISNIGIVGGT 188
MDT GL+VP +KN+QI SI +IA ELN LQ+ GS QL DLTGGTFT+SNIG +GGT
Sbjct: 348 MDTEQGLIVPNVKNVQICSIFDIATELNRLQKLGSVSQLSTTDLTGGTFTLSNIGSIGGT 407
Query: 187 YTKPVIFPPQVAIGALGKIQVLPRFDSXRE 98
+ KPVI PP+VAIGALG I+ +PRF+ E
Sbjct: 408 FAKPVIMPPEVAIGALGSIKAIPRFNQKGE 437
Score = 55.2 bits (127), Expect = 2e-07
Identities = 24/35 (68%), Positives = 29/35 (82%)
Frame = -2
Query: 105 QGNVVKAHILSVSWSADHRVIDGVTMARFSNXLKN 1
+G V KA I++VSWSADHRVIDG TM+RFSN K+
Sbjct: 435 KGEVYKAQIMNVSWSADHRVIDGATMSRFSNLWKS 469
>L37418-1|AAB59629.1| 453|Homo sapiens dihydrolipoamide
succinyltransferase protein.
Length = 453
Score = 109 bits (262), Expect = 1e-23
Identities = 51/142 (35%), Positives = 90/142 (63%), Gaps = 1/142 (0%)
Frame = -1
Query: 571 DEYNVTKLVESRAALKKQ-AEERGIRLTYMPIIIKAASLSLSYLPILNSSLDSSCENLIY 395
+E +++ + E RA K+ ++ ++L +M +KA++ +L P++N+ +D + + ++Y
Sbjct: 252 NEIDMSNIQEMRARHKEAFLKKHNLKLGFMSAFVKASAFALQEQPVVNAVIDDTTKEVVY 311
Query: 394 KASHNIGVAMDTPNGLVVPVIKNIQIKSILEIAQELNTLQEKGSKGQLGLNDLTGGTFTI 215
+ +I VA+ TP GLVVPVI+N++ + +I + + L EK K +L + D+ GGTFTI
Sbjct: 312 RDYIDISVAVATPRGLVVPVIRNVEAMNFADIERTITELGEKARKNELAIEDMDGGTFTI 371
Query: 214 SNIGIVGGTYTKPVIFPPQVAI 149
SN G+ G + P+I PPQ AI
Sbjct: 372 SNGGVFGSLFGTPIINPPQSAI 393
>CR456727-1|CAG33008.1| 453|Homo sapiens DLST protein.
Length = 453
Score = 109 bits (262), Expect = 1e-23
Identities = 51/142 (35%), Positives = 90/142 (63%), Gaps = 1/142 (0%)
Frame = -1
Query: 571 DEYNVTKLVESRAALKKQ-AEERGIRLTYMPIIIKAASLSLSYLPILNSSLDSSCENLIY 395
+E +++ + E RA K+ ++ ++L +M +KA++ +L P++N+ +D + + ++Y
Sbjct: 252 NEIDMSNIQEMRARHKEAFLKKHNLKLGFMSAFVKASAFALQEQPVVNAVIDDTTKEVVY 311
Query: 394 KASHNIGVAMDTPNGLVVPVIKNIQIKSILEIAQELNTLQEKGSKGQLGLNDLTGGTFTI 215
+ +I VA+ TP GLVVPVI+N++ + +I + + L EK K +L + D+ GGTFTI
Sbjct: 312 RDYIDISVAVATPRGLVVPVIRNVEAMNFADIERTITELGEKARKNELAIEDMDGGTFTI 371
Query: 214 SNIGIVGGTYTKPVIFPPQVAI 149
SN G+ G + P+I PPQ AI
Sbjct: 372 SNGGVFGSLFGTPIINPPQSAI 393
>BC001922-1|AAH01922.1| 453|Homo sapiens dihydrolipoamide
S-succinyltransferase (E2 component of 2-oxo-glutarate
complex protein.
Length = 453
Score = 109 bits (262), Expect = 1e-23
Identities = 51/142 (35%), Positives = 90/142 (63%), Gaps = 1/142 (0%)
Frame = -1
Query: 571 DEYNVTKLVESRAALKKQ-AEERGIRLTYMPIIIKAASLSLSYLPILNSSLDSSCENLIY 395
+E +++ + E RA K+ ++ ++L +M +KA++ +L P++N+ +D + + ++Y
Sbjct: 252 NEIDMSNIQEMRARHKEAFLKKHNLKLGFMSAFVKASAFALQEQPVVNAVIDDTTKEVVY 311
Query: 394 KASHNIGVAMDTPNGLVVPVIKNIQIKSILEIAQELNTLQEKGSKGQLGLNDLTGGTFTI 215
+ +I VA+ TP GLVVPVI+N++ + +I + + L EK K +L + D+ GGTFTI
Sbjct: 312 RDYIDISVAVATPRGLVVPVIRNVEAMNFADIERTITELGEKARKNELAIEDMDGGTFTI 371
Query: 214 SNIGIVGGTYTKPVIFPPQVAI 149
SN G+ G + P+I PPQ AI
Sbjct: 372 SNGGVFGSLFGTPIINPPQSAI 393
>BC000302-1|AAH00302.1| 453|Homo sapiens dihydrolipoamide
S-succinyltransferase (E2 component of 2-oxo-glutarate
complex protein.
Length = 453
Score = 109 bits (262), Expect = 1e-23
Identities = 51/142 (35%), Positives = 90/142 (63%), Gaps = 1/142 (0%)
Frame = -1
Query: 571 DEYNVTKLVESRAALKKQ-AEERGIRLTYMPIIIKAASLSLSYLPILNSSLDSSCENLIY 395
+E +++ + E RA K+ ++ ++L +M +KA++ +L P++N+ +D + + ++Y
Sbjct: 252 NEIDMSNIQEMRARHKEAFLKKHNLKLGFMSAFVKASAFALQEQPVVNAVIDDTTKEVVY 311
Query: 394 KASHNIGVAMDTPNGLVVPVIKNIQIKSILEIAQELNTLQEKGSKGQLGLNDLTGGTFTI 215
+ +I VA+ TP GLVVPVI+N++ + +I + + L EK K +L + D+ GGTFTI
Sbjct: 312 RDYIDISVAVATPRGLVVPVIRNVEAMNFADIERTITELGEKARKNELAIEDMDGGTFTI 371
Query: 214 SNIGIVGGTYTKPVIFPPQVAI 149
SN G+ G + P+I PPQ AI
Sbjct: 372 SNGGVFGSLFGTPIINPPQSAI 393
>AC006530-2|AAD30181.1| 453|Homo sapiens alpha-KG-E2 protein.
Length = 453
Score = 109 bits (262), Expect = 1e-23
Identities = 51/142 (35%), Positives = 90/142 (63%), Gaps = 1/142 (0%)
Frame = -1
Query: 571 DEYNVTKLVESRAALKKQ-AEERGIRLTYMPIIIKAASLSLSYLPILNSSLDSSCENLIY 395
+E +++ + E RA K+ ++ ++L +M +KA++ +L P++N+ +D + + ++Y
Sbjct: 252 NEIDMSNIQEMRARHKEAFLKKHNLKLGFMSAFVKASAFALQEQPVVNAVIDDTTKEVVY 311
Query: 394 KASHNIGVAMDTPNGLVVPVIKNIQIKSILEIAQELNTLQEKGSKGQLGLNDLTGGTFTI 215
+ +I VA+ TP GLVVPVI+N++ + +I + + L EK K +L + D+ GGTFTI
Sbjct: 312 RDYIDISVAVATPRGLVVPVIRNVEAMNFADIERTITELGEKARKNELAIEDMDGGTFTI 371
Query: 214 SNIGIVGGTYTKPVIFPPQVAI 149
SN G+ G + P+I PPQ AI
Sbjct: 372 SNGGVFGSLFGTPIINPPQSAI 393
>D26535-1|BAA05536.1| 453|Homo sapiens dihydrolipoamide
succinyltransferase protein.
Length = 453
Score = 108 bits (259), Expect = 3e-23
Identities = 51/142 (35%), Positives = 89/142 (62%), Gaps = 1/142 (0%)
Frame = -1
Query: 571 DEYNVTKLVESRAALKKQ-AEERGIRLTYMPIIIKAASLSLSYLPILNSSLDSSCENLIY 395
+E +++ + E RA K+ ++ ++L +M +KA++ +L P++N+ +D + + ++Y
Sbjct: 252 NEIDMSNIQEMRARHKEAFLKKHNLKLGFMSAFVKASAFALQEQPVVNAVIDDTTKEVVY 311
Query: 394 KASHNIGVAMDTPNGLVVPVIKNIQIKSILEIAQELNTLQEKGSKGQLGLNDLTGGTFTI 215
+I VA+ TP GLVVPVI+N++ + +I + + L EK K +L + D+ GGTFTI
Sbjct: 312 TDYIDISVAVATPRGLVVPVIRNVEAMNFADIERTITELGEKARKNELAIEDMDGGTFTI 371
Query: 214 SNIGIVGGTYTKPVIFPPQVAI 149
SN G+ G + P+I PPQ AI
Sbjct: 372 SNGGVFGSLFGTPIINPPQSAI 393
>D16373-1|BAA03871.1| 453|Homo sapiens mitochondrial
dihydrolipoamide succinyltransferase protein.
Length = 453
Score = 106 bits (254), Expect = 1e-22
Identities = 50/142 (35%), Positives = 89/142 (62%), Gaps = 1/142 (0%)
Frame = -1
Query: 571 DEYNVTKLVESRAALKKQ-AEERGIRLTYMPIIIKAASLSLSYLPILNSSLDSSCENLIY 395
+E +++ + E RA K+ ++ ++L +M +KA++ +L P++N+ +D + + ++Y
Sbjct: 252 NEIDMSNIQEMRARHKEAFLKKHNLKLGFMSAFVKASAFALQEQPVVNAVIDDTTKEVVY 311
Query: 394 KASHNIGVAMDTPNGLVVPVIKNIQIKSILEIAQELNTLQEKGSKGQLGLNDLTGGTFTI 215
+ +I VA+ TP GLVVPVI+N++ + +I + + L EK K +L + D+ GGTFTI
Sbjct: 312 RDYIDISVAVATPRGLVVPVIRNVEAMNFADIERTITELGEKARKNELAIEDMDGGTFTI 371
Query: 214 SNIGIVGGTYTKPVIFPPQVAI 149
SN G+ G + +I PPQ AI
Sbjct: 372 SNGGVFGSLFGTTIINPPQSAI 393
>S72422-1|AAB31066.1| 451|Homo sapiens alpha-ketoglutarate
dehydrogenase complex dihydrolipoyl succinyltransferase
protein.
Length = 451
Score = 102 bits (245), Expect = 1e-21
Identities = 51/167 (30%), Positives = 95/167 (56%), Gaps = 2/167 (1%)
Frame = -1
Query: 631 QRAMVKSMTEAMK-IPHFVFSDEYNVTKLVESRAALKKQ-AEERGIRLTYMPIIIKAASL 458
++ + + + EA +P +E +V+ + + RA K+ ++ ++L +M +KA++
Sbjct: 230 RQCIAQRLKEAQNTVPMLTIFNEIDVSNIQKMRARHKEAFLKKHNLKLGFMSASVKASAF 289
Query: 457 SLSYLPILNSSLDSSCENLIYKASHNIGVAMDTPNGLVVPVIKNIQIKSILEIAQELNTL 278
+L P++N+ +D + ++Y+ +I VA+ TP GLVVPVI+N++ + +I Q + L
Sbjct: 290 ALQEQPVVNAVIDDITKEVVYRDYIDISVAVATPQGLVVPVIRNVEAMNYADIEQTITEL 349
Query: 277 QEKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALG 137
EK K + + D+ GGTFTISN G+ G + P+ P +G G
Sbjct: 350 GEKARKNEFAIEDMDGGTFTISNGGVFGSLFEHPLSTPLSAILGMHG 396
>Y00978-1|CAA68787.1| 615|Homo sapiens PDC-E2 precursor (AA -54 to
561) protein.
Length = 615
Score = 94.7 bits (225), Expect = 3e-19
Identities = 55/174 (31%), Positives = 100/174 (57%), Gaps = 3/174 (1%)
Frame = -1
Query: 649 VPVTGFQRAMVKSMTEAMK-IPHFVFSDEYNVTKLVESRAALKKQAEERGIRLTYMPIII 473
+P++ +R + + + ++ + IPH+ S + N+ +++ R L K E R +++ II
Sbjct: 391 IPISNIRRVIAQRLMQSKQTIPHYYLSIDVNMGEVLLVRKELNKILEGRS-KISVNDFII 449
Query: 472 KAASLSLSYLPILNSSLDSSCENLIYKASH--NIGVAMDTPNGLVVPVIKNIQIKSILEI 299
KA++L+ +P NSS + + + +H ++ VA+ TP GL+ P++ N IK + I
Sbjct: 450 KASALACLKVPEANSSWMDT----VIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGVETI 505
Query: 298 AQELNTLQEKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALG 137
A ++ +L K +G+L ++ GGTFTISN+G+ G +I PPQ I A+G
Sbjct: 506 ANDVVSLATKAREGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAIG 559
>BC039084-1|AAH39084.1| 647|Homo sapiens dihydrolipoamide
S-acetyltransferase (E2 component of pyruvate
dehydrogenase co protein.
Length = 647
Score = 94.7 bits (225), Expect = 3e-19
Identities = 55/174 (31%), Positives = 100/174 (57%), Gaps = 3/174 (1%)
Frame = -1
Query: 649 VPVTGFQRAMVKSMTEAMK-IPHFVFSDEYNVTKLVESRAALKKQAEERGIRLTYMPIII 473
+P++ +R + + + ++ + IPH+ S + N+ +++ R L K E R +++ II
Sbjct: 423 IPISNIRRVIAQRLMQSKQTIPHYYLSIDVNMGEVLLVRKELNKILEGRS-KISVNDFII 481
Query: 472 KAASLSLSYLPILNSSLDSSCENLIYKASH--NIGVAMDTPNGLVVPVIKNIQIKSILEI 299
KA++L+ +P NSS + + + +H ++ VA+ TP GL+ P++ N IK + I
Sbjct: 482 KASALACLKVPEANSSWMDT----VIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGVETI 537
Query: 298 AQELNTLQEKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALG 137
A ++ +L K +G+L ++ GGTFTISN+G+ G +I PPQ I A+G
Sbjct: 538 ANDVVSLATKAREGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAIG 591
>AK223596-1|BAD97316.1| 647|Homo sapiens dihydrolipoamide
S-acetyltransferase (E2 component of pyruvate
dehydrogenase co protein.
Length = 647
Score = 93.9 bits (223), Expect = 6e-19
Identities = 55/174 (31%), Positives = 99/174 (56%), Gaps = 3/174 (1%)
Frame = -1
Query: 649 VPVTGFQRAMVKSMTEAMK-IPHFVFSDEYNVTKLVESRAALKKQAEERGIRLTYMPIII 473
+P++ +R + + + ++ + IPH+ S N+ +++ R L K E R +++ II
Sbjct: 423 IPISNIRRVIAQRLMQSKQTIPHYYLSINVNMGEVLLVRKELNKILEGRS-KISVNDFII 481
Query: 472 KAASLSLSYLPILNSSLDSSCENLIYKASH--NIGVAMDTPNGLVVPVIKNIQIKSILEI 299
KA++L+ +P NSS + + + +H ++ VA+ TP GL+ P++ N IK + I
Sbjct: 482 KASALACLKVPEANSSWMDT----VIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGVETI 537
Query: 298 AQELNTLQEKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALG 137
A ++ +L K +G+L ++ GGTFTISN+G+ G +I PPQ I A+G
Sbjct: 538 ANDVVSLATKAREGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAIG 591
>J03866-1|AAA62253.1| 613|Homo sapiens dihydrolipoamide
acetyltransferase protein.
Length = 613
Score = 89.0 bits (211), Expect = 2e-17
Identities = 57/175 (32%), Positives = 99/175 (56%), Gaps = 4/175 (2%)
Frame = -1
Query: 649 VPVTGFQRAMVKSMTEAMK-IPHF-VFSDEYNVTKLVESRAALKKQAEERGIRLTYMPII 476
+P++ +R + + + ++ + IPH+ + S +Y LV R L K E R +++ I
Sbjct: 390 IPISNIRRVIAQRLMQSKQTIPHYYLLSCKYGEVLLV--RKELNKILEGRS-KISVNDFI 446
Query: 475 IKAASLSLSYLPILNSSLDSSCENLIYKASH--NIGVAMDTPNGLVVPVIKNIQIKSILE 302
IKA++L+ +P NSS + + + +H ++ VA+ TP GL+ P++ N IK +
Sbjct: 447 IKASALACLKVPEANSSWMDT----VIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGVET 502
Query: 301 IAQELNTLQEKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALG 137
IA ++ +L K +G+L ++ GGTFTISN+G+ G +I PPQ I A+G
Sbjct: 503 IANDVVSLATKAREGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAIG 557
>Y13145-1|CAA73606.1| 501|Homo sapiens protein X protein.
Length = 501
Score = 87.0 bits (206), Expect = 7e-17
Identities = 56/185 (30%), Positives = 97/185 (52%), Gaps = 1/185 (0%)
Frame = -1
Query: 649 VPVTGFQRAMVKSMTEAMK-IPHFVFSDEYNVTKLVESRAALKKQAEERGIRLTYMPIII 473
+P + +R + K +TE+ +PH + + ++ +++ R L K I+++ II
Sbjct: 278 IPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQDLVKD----DIKVSVNDFII 333
Query: 472 KAASLSLSYLPILNSSLDSSCENLIYKASHNIGVAMDTPNGLVVPVIKNIQIKSILEIAQ 293
KAA+++L +P +N S D + +I VA+ T GL+ P+IK+ K I EIA
Sbjct: 334 KAAAVTLKQMPDVNVSWDGEGPKQL--PFIDISVAVATDKGLLTPIIKDAAAKGIQEIAD 391
Query: 292 ELNTLQEKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRF 113
+ L +K G+L + GG+F+ISN+G+ G VI PPQ I A+G+ + + +
Sbjct: 392 SVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRFRPVLKL 451
Query: 112 DSXRE 98
E
Sbjct: 452 TEDEE 456
>U82328-1|AAC39661.1| 501|Homo sapiens pyruvate dehydrogenase
complex protein X subunit precursor protein.
Length = 501
Score = 87.0 bits (206), Expect = 7e-17
Identities = 56/185 (30%), Positives = 97/185 (52%), Gaps = 1/185 (0%)
Frame = -1
Query: 649 VPVTGFQRAMVKSMTEAMK-IPHFVFSDEYNVTKLVESRAALKKQAEERGIRLTYMPIII 473
+P + +R + K +TE+ +PH + + ++ +++ R L K I+++ II
Sbjct: 278 IPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQDLVKD----DIKVSVNDFII 333
Query: 472 KAASLSLSYLPILNSSLDSSCENLIYKASHNIGVAMDTPNGLVVPVIKNIQIKSILEIAQ 293
KAA+++L +P +N S D + +I VA+ T GL+ P+IK+ K I EIA
Sbjct: 334 KAAAVTLKQMPDVNVSWDGEGPKQL--PFIDISVAVATDKGLLTPIIKDAAAKGIQEIAD 391
Query: 292 ELNTLQEKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRF 113
+ L +K G+L + GG+F+ISN+G+ G VI PPQ I A+G+ + + +
Sbjct: 392 SVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRFRPVLKL 451
Query: 112 DSXRE 98
E
Sbjct: 452 TEDEE 456
>U79296-1|AAB50223.1| 375|Homo sapiens dihyrolipoamide acetyl
transferase protein.
Length = 375
Score = 87.0 bits (206), Expect = 7e-17
Identities = 56/185 (30%), Positives = 97/185 (52%), Gaps = 1/185 (0%)
Frame = -1
Query: 649 VPVTGFQRAMVKSMTEAMK-IPHFVFSDEYNVTKLVESRAALKKQAEERGIRLTYMPIII 473
+P + +R + K +TE+ +PH + + ++ +++ R L K I+++ II
Sbjct: 152 IPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQDLVKD----DIKVSVNDFII 207
Query: 472 KAASLSLSYLPILNSSLDSSCENLIYKASHNIGVAMDTPNGLVVPVIKNIQIKSILEIAQ 293
KAA+++L +P +N S D + +I VA+ T GL+ P+IK+ K I EIA
Sbjct: 208 KAAAVTLKQMPDVNVSWDGEGPKQL--PFIDISVAVATDKGLLTPIIKDAAAKGIQEIAD 265
Query: 292 ELNTLQEKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRF 113
+ L +K G+L + GG+F+ISN+G+ G VI PPQ I A+G+ + + +
Sbjct: 266 SVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRFRPVLKL 325
Query: 112 DSXRE 98
E
Sbjct: 326 TEDEE 330
>AJ298105-1|CAC18649.1| 501|Homo sapiens lipoyl-containing
component X protein.
Length = 501
Score = 87.0 bits (206), Expect = 7e-17
Identities = 56/185 (30%), Positives = 97/185 (52%), Gaps = 1/185 (0%)
Frame = -1
Query: 649 VPVTGFQRAMVKSMTEAMK-IPHFVFSDEYNVTKLVESRAALKKQAEERGIRLTYMPIII 473
+P + +R + K +TE+ +PH + + ++ +++ R L K I+++ II
Sbjct: 278 IPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQDLVKD----DIKVSVNDFII 333
Query: 472 KAASLSLSYLPILNSSLDSSCENLIYKASHNIGVAMDTPNGLVVPVIKNIQIKSILEIAQ 293
KAA+++L +P +N S D + +I VA+ T GL+ P+IK+ K I EIA
Sbjct: 334 KAAAVTLKQMPDVNVSWDGEGPKQL--PFIDISVAVATDKGLLTPIIKDAAAKGIQEIAD 391
Query: 292 ELNTLQEKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRF 113
+ L +K G+L + GG+F+ISN+G+ G VI PPQ I A+G+ + + +
Sbjct: 392 SVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRFRPVLKL 451
Query: 112 DSXRE 98
E
Sbjct: 452 TEDEE 456
>AF001437-1|AAB66315.1| 501|Homo sapiens dihydrolipoamide
dehydrogenase-binding protein protein.
Length = 501
Score = 87.0 bits (206), Expect = 7e-17
Identities = 56/185 (30%), Positives = 97/185 (52%), Gaps = 1/185 (0%)
Frame = -1
Query: 649 VPVTGFQRAMVKSMTEAMK-IPHFVFSDEYNVTKLVESRAALKKQAEERGIRLTYMPIII 473
+P + +R + K +TE+ +PH + + ++ +++ R L K I+++ II
Sbjct: 278 IPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQDLVKD----DIKVSVNDFII 333
Query: 472 KAASLSLSYLPILNSSLDSSCENLIYKASHNIGVAMDTPNGLVVPVIKNIQIKSILEIAQ 293
KAA+++L +P +N S D + +I VA+ T GL+ P+IK+ K I EIA
Sbjct: 334 KAAAVTLKQMPDVNVSWDGEGPKQL--PFIDISVAVATDKGLLTPIIKDAAAKGIQEIAD 391
Query: 292 ELNTLQEKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRF 113
+ L +K G+L + GG+F+ISN+G+ G VI PPQ I A+G+ + + +
Sbjct: 392 SVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRFRPVLKL 451
Query: 112 DSXRE 98
E
Sbjct: 452 TEDEE 456
>BC010389-1|AAH10389.1| 501|Homo sapiens pyruvate dehydrogenase
complex, component X protein.
Length = 501
Score = 86.6 bits (205), Expect = 9e-17
Identities = 56/185 (30%), Positives = 97/185 (52%), Gaps = 1/185 (0%)
Frame = -1
Query: 649 VPVTGFQRAMVKSMTEAMK-IPHFVFSDEYNVTKLVESRAALKKQAEERGIRLTYMPIII 473
+P + +R + K +TE+ +PH + + ++ +++ R L K I+++ II
Sbjct: 278 IPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQDLVKD----DIKVSVNDFII 333
Query: 472 KAASLSLSYLPILNSSLDSSCENLIYKASHNIGVAMDTPNGLVVPVIKNIQIKSILEIAQ 293
KAA+++L +P +N S D + +I VA+ T GL+ P+IK+ K I EIA
Sbjct: 334 KAAAVTLKQMPDVNVSWDGEGPKQL--PFIDISVAVATVKGLLTPIIKDAAAKGIQEIAD 391
Query: 292 ELNTLQEKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRF 113
+ L +K G+L + GG+F+ISN+G+ G VI PPQ I A+G+ + + +
Sbjct: 392 SVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRFRPVLKL 451
Query: 112 DSXRE 98
E
Sbjct: 452 TEDEE 456
>M19301-1|AAA59200.1| 315|Homo sapiens DBT protein.
Length = 315
Score = 74.5 bits (175), Expect = 4e-13
Identities = 36/86 (41%), Positives = 57/86 (66%)
Frame = -1
Query: 727 PGSVRAVEIPVTKAQARVELALEDKVVPVTGFQRAMVKSMTEAMKIPHFVFSDEYNVTKL 548
P + + +P+ ++ V +DK P+ GFQ+AMVK+M+ A+KIPHF + DE ++T+L
Sbjct: 224 PPKPKDMTVPILVSKPPVFTG-KDKTEPIKGFQKAMVKTMSAALKIPHFGYCDEIDLTEL 282
Query: 547 VESRAALKKQAEERGIRLTYMPIIIK 470
V+ R LK A RGI+L++MP +K
Sbjct: 283 VKLREELKPIAFARGIKLSFMPFFLK 308
>AL445928-10|CAH72258.1| 320|Homo sapiens dihydrolipoamide branched
chain transacylase E2 protein.
Length = 320
Score = 74.5 bits (175), Expect = 4e-13
Identities = 36/86 (41%), Positives = 57/86 (66%)
Frame = -1
Query: 727 PGSVRAVEIPVTKAQARVELALEDKVVPVTGFQRAMVKSMTEAMKIPHFVFSDEYNVTKL 548
P + + +P+ ++ V +DK P+ GFQ+AMVK+M+ A+KIPHF + DE ++T+L
Sbjct: 229 PPKPKDMTVPILVSKPPVFTG-KDKTEPIKGFQKAMVKTMSAALKIPHFGYCDEIDLTEL 287
Query: 547 VESRAALKKQAEERGIRLTYMPIIIK 470
V+ R LK A RGI+L++MP +K
Sbjct: 288 VKLREELKPIAFARGIKLSFMPFFLK 313
>X13822-1|CAA32052.1| 220|Homo sapiens dihydrolipoamide
S-acetyltransferase protein.
Length = 220
Score = 61.3 bits (142), Expect = 4e-09
Identities = 37/136 (27%), Positives = 76/136 (55%), Gaps = 3/136 (2%)
Frame = -1
Query: 649 VPVTGFQRAMVKSMTEAMK-IPHFVFSDEYNVTKLVESRAALKKQAEERGIRLTYMPIII 473
+P++ +R + + + ++ + IPH+ S + N+ +++ R L K E R +++ II
Sbjct: 87 IPISNIRRVIAQRLMQSKQTIPHYYLSIDVNMGEVLLVRKELNKILEGRS-KISVNDFII 145
Query: 472 KAASLSLSYLPILNSSLDSSCENLIYKASH--NIGVAMDTPNGLVVPVIKNIQIKSILEI 299
K ++L+ +P NSS + + + +H ++ VA+ TP GL+ P++ N IK + I
Sbjct: 146 KRSALACLKVPEANSSWMDT----VIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGVETI 201
Query: 298 AQELNTLQEKGSKGQL 251
A ++ +L K +G+L
Sbjct: 202 ANDVVSLATKAREGKL 217
>X53416-1|CAA37495.1| 2647|Homo sapiens protein ( Human mRNA for
actin-binding protein (filamin) (ABP-280). ).
Length = 2647
Score = 35.9 bits (79), Expect = 0.16
Identities = 23/73 (31%), Positives = 33/73 (45%)
Frame = -1
Query: 274 EKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSXRER 95
E G ++ + D GT TI+ I + G YT + + Q K+QV P D+ +
Sbjct: 1200 EAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQ 1259
Query: 94 CEGSHSVGQLVCR 56
C G GQ V R
Sbjct: 1260 CYGPGIEGQGVFR 1272
Score = 31.1 bits (67), Expect = 4.6
Identities = 17/59 (28%), Positives = 28/59 (47%)
Frame = -1
Query: 262 KGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSXRERCEG 86
+ QL D GT ++S + G Y ++F G+ K V+P FD+ + +C G
Sbjct: 1109 EAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSG 1167
>L44140-1|AAA92644.1| 2647|Homo sapiens filamin protein.
Length = 2647
Score = 35.9 bits (79), Expect = 0.16
Identities = 23/73 (31%), Positives = 33/73 (45%)
Frame = -1
Query: 274 EKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSXRER 95
E G ++ + D GT TI+ I + G YT + + Q K+QV P D+ +
Sbjct: 1200 EAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQ 1259
Query: 94 CEGSHSVGQLVCR 56
C G GQ V R
Sbjct: 1260 CYGPGIEGQGVFR 1272
Score = 31.1 bits (67), Expect = 4.6
Identities = 17/59 (28%), Positives = 28/59 (47%)
Frame = -1
Query: 262 KGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSXRERCEG 86
+ QL D GT ++S + G Y ++F G+ K V+P FD+ + +C G
Sbjct: 1109 EAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSG 1167
>BX936346-3|CAI43225.1| 2647|Homo sapiens filamin A, alpha (actin
binding protein 280) protein.
Length = 2647
Score = 35.9 bits (79), Expect = 0.16
Identities = 23/73 (31%), Positives = 33/73 (45%)
Frame = -1
Query: 274 EKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSXRER 95
E G ++ + D GT TI+ I + G YT + + Q K+QV P D+ +
Sbjct: 1200 EAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQ 1259
Query: 94 CEGSHSVGQLVCR 56
C G GQ V R
Sbjct: 1260 CYGPGIEGQGVFR 1272
Score = 31.1 bits (67), Expect = 4.6
Identities = 17/59 (28%), Positives = 28/59 (47%)
Frame = -1
Query: 262 KGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSXRERCEG 86
+ QL D GT ++S + G Y ++F G+ K V+P FD+ + +C G
Sbjct: 1109 EAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSG 1167
>BX936346-2|CAI43227.1| 2639|Homo sapiens filamin A, alpha (actin
binding protein 280) protein.
Length = 2639
Score = 35.9 bits (79), Expect = 0.16
Identities = 23/73 (31%), Positives = 33/73 (45%)
Frame = -1
Query: 274 EKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSXRER 95
E G ++ + D GT TI+ I + G YT + + Q K+QV P D+ +
Sbjct: 1200 EAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQ 1259
Query: 94 CEGSHSVGQLVCR 56
C G GQ V R
Sbjct: 1260 CYGPGIEGQGVFR 1272
Score = 31.1 bits (67), Expect = 4.6
Identities = 17/59 (28%), Positives = 28/59 (47%)
Frame = -1
Query: 262 KGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSXRERCEG 86
+ QL D GT ++S + G Y ++F G+ K V+P FD+ + +C G
Sbjct: 1109 EAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSG 1167
>BX936346-1|CAI43226.1| 2607|Homo sapiens filamin A, alpha (actin
binding protein 280) protein.
Length = 2607
Score = 35.9 bits (79), Expect = 0.16
Identities = 23/73 (31%), Positives = 33/73 (45%)
Frame = -1
Query: 274 EKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSXRER 95
E G ++ + D GT TI+ I + G YT + + Q K+QV P D+ +
Sbjct: 1200 EAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQ 1259
Query: 94 CEGSHSVGQLVCR 56
C G GQ V R
Sbjct: 1260 CYGPGIEGQGVFR 1272
Score = 31.1 bits (67), Expect = 4.6
Identities = 17/59 (28%), Positives = 28/59 (47%)
Frame = -1
Query: 262 KGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSXRERCEG 86
+ QL D GT ++S + G Y ++F G+ K V+P FD+ + +C G
Sbjct: 1109 EAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSG 1167
>BX664723-3|CAI43197.1| 2647|Homo sapiens filamin A, alpha (actin
binding protein 280) protein.
Length = 2647
Score = 35.9 bits (79), Expect = 0.16
Identities = 23/73 (31%), Positives = 33/73 (45%)
Frame = -1
Query: 274 EKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSXRER 95
E G ++ + D GT TI+ I + G YT + + Q K+QV P D+ +
Sbjct: 1200 EAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQ 1259
Query: 94 CEGSHSVGQLVCR 56
C G GQ V R
Sbjct: 1260 CYGPGIEGQGVFR 1272
Score = 31.1 bits (67), Expect = 4.6
Identities = 17/59 (28%), Positives = 28/59 (47%)
Frame = -1
Query: 262 KGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSXRERCEG 86
+ QL D GT ++S + G Y ++F G+ K V+P FD+ + +C G
Sbjct: 1109 EAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSG 1167
>BX664723-2|CAI43199.1| 2639|Homo sapiens filamin A, alpha (actin
binding protein 280) protein.
Length = 2639
Score = 35.9 bits (79), Expect = 0.16
Identities = 23/73 (31%), Positives = 33/73 (45%)
Frame = -1
Query: 274 EKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSXRER 95
E G ++ + D GT TI+ I + G YT + + Q K+QV P D+ +
Sbjct: 1200 EAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQ 1259
Query: 94 CEGSHSVGQLVCR 56
C G GQ V R
Sbjct: 1260 CYGPGIEGQGVFR 1272
Score = 31.1 bits (67), Expect = 4.6
Identities = 17/59 (28%), Positives = 28/59 (47%)
Frame = -1
Query: 262 KGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSXRERCEG 86
+ QL D GT ++S + G Y ++F G+ K V+P FD+ + +C G
Sbjct: 1109 EAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSG 1167
>BX664723-1|CAI43198.1| 2607|Homo sapiens filamin A, alpha (actin
binding protein 280) protein.
Length = 2607
Score = 35.9 bits (79), Expect = 0.16
Identities = 23/73 (31%), Positives = 33/73 (45%)
Frame = -1
Query: 274 EKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSXRER 95
E G ++ + D GT TI+ I + G YT + + Q K+QV P D+ +
Sbjct: 1200 EAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQ 1259
Query: 94 CEGSHSVGQLVCR 56
C G GQ V R
Sbjct: 1260 CYGPGIEGQGVFR 1272
Score = 31.1 bits (67), Expect = 4.6
Identities = 17/59 (28%), Positives = 28/59 (47%)
Frame = -1
Query: 262 KGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSXRERCEG 86
+ QL D GT ++S + G Y ++F G+ K V+P FD+ + +C G
Sbjct: 1109 EAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSG 1167
>AK090427-1|BAC03408.1| 2651|Homo sapiens FLJ00343 protein protein.
Length = 2651
Score = 35.9 bits (79), Expect = 0.16
Identities = 23/73 (31%), Positives = 33/73 (45%)
Frame = -1
Query: 274 EKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSXRER 95
E G ++ + D GT TI+ I + G YT + + Q K+QV P D+ +
Sbjct: 1212 EAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQ 1271
Query: 94 CEGSHSVGQLVCR 56
C G GQ V R
Sbjct: 1272 CYGPGIEGQGVFR 1284
Score = 31.1 bits (67), Expect = 4.6
Identities = 17/59 (28%), Positives = 28/59 (47%)
Frame = -1
Query: 262 KGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSXRERCEG 86
+ QL D GT ++S + G Y ++F G+ K V+P FD+ + +C G
Sbjct: 1121 EAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSG 1179
>AK074048-1|BAB84874.1| 1455|Homo sapiens FLJ00119 protein protein.
Length = 1455
Score = 35.9 bits (79), Expect = 0.16
Identities = 23/73 (31%), Positives = 33/73 (45%)
Frame = -1
Query: 274 EKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSXRER 95
E G ++ + D GT TI+ I + G YT + + Q K+QV P D+ +
Sbjct: 16 EAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQ 75
Query: 94 CEGSHSVGQLVCR 56
C G GQ V R
Sbjct: 76 CYGPGIEGQGVFR 88
>AB191260-1|BAD52436.1| 2620|Homo sapiens filamin A protein.
Length = 2620
Score = 35.9 bits (79), Expect = 0.16
Identities = 23/73 (31%), Positives = 33/73 (45%)
Frame = -1
Query: 274 EKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSXRER 95
E G ++ + D GT TI+ I + G YT + + Q K+QV P D+ +
Sbjct: 1173 EAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQ 1232
Query: 94 CEGSHSVGQLVCR 56
C G GQ V R
Sbjct: 1233 CYGPGIEGQGVFR 1245
Score = 31.1 bits (67), Expect = 4.6
Identities = 17/59 (28%), Positives = 28/59 (47%)
Frame = -1
Query: 262 KGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSXRERCEG 86
+ QL D GT ++S + G Y ++F G+ K V+P FD+ + +C G
Sbjct: 1082 EAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSG 1140
>AB191259-1|BAD52435.1| 2612|Homo sapiens filamin A protein.
Length = 2612
Score = 35.9 bits (79), Expect = 0.16
Identities = 23/73 (31%), Positives = 33/73 (45%)
Frame = -1
Query: 274 EKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSXRER 95
E G ++ + D GT TI+ I + G YT + + Q K+QV P D+ +
Sbjct: 1173 EAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQ 1232
Query: 94 CEGSHSVGQLVCR 56
C G GQ V R
Sbjct: 1233 CYGPGIEGQGVFR 1245
Score = 31.1 bits (67), Expect = 4.6
Identities = 17/59 (28%), Positives = 28/59 (47%)
Frame = -1
Query: 262 KGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSXRERCEG 86
+ QL D GT ++S + G Y ++F G+ K V+P FD+ + +C G
Sbjct: 1082 EAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSG 1140
>D83597-1|BAA12019.1| 661|Homo sapiens RP105 protein.
Length = 661
Score = 34.7 bits (76), Expect = 0.37
Identities = 18/56 (32%), Positives = 33/56 (58%)
Frame = +1
Query: 43 DDSVVCRPTDRQNVSLHNVPLXNQISGEPVFFLMLQLQLVAGILPVSCKYLLQFRY 210
+++ P + V L +V L I+ +FFL++ L L+A +L + KYLL+++Y
Sbjct: 603 EETTCANPPSLRGVKLSDVKLSCGITAIGIFFLIVFLLLLAILLFFAVKYLLRWKY 658
>BC109070-1|AAI09071.1| 661|Homo sapiens CD180 molecule protein.
Length = 661
Score = 34.7 bits (76), Expect = 0.37
Identities = 18/56 (32%), Positives = 33/56 (58%)
Frame = +1
Query: 43 DDSVVCRPTDRQNVSLHNVPLXNQISGEPVFFLMLQLQLVAGILPVSCKYLLQFRY 210
+++ P + V L +V L I+ +FFL++ L L+A +L + KYLL+++Y
Sbjct: 603 EETTCANPPSLRGVKLSDVKLSCGITAIGIFFLIVFLLLLAILLFFAVKYLLRWKY 658
>BC109069-1|AAI09070.1| 661|Homo sapiens CD180 molecule protein.
Length = 661
Score = 34.7 bits (76), Expect = 0.37
Identities = 18/56 (32%), Positives = 33/56 (58%)
Frame = +1
Query: 43 DDSVVCRPTDRQNVSLHNVPLXNQISGEPVFFLMLQLQLVAGILPVSCKYLLQFRY 210
+++ P + V L +V L I+ +FFL++ L L+A +L + KYLL+++Y
Sbjct: 603 EETTCANPPSLRGVKLSDVKLSCGITAIGIFFLIVFLLLLAILLFFAVKYLLRWKY 658
>BX641085-1|CAE46040.1| 2422|Homo sapiens hypothetical protein
protein.
Length = 2422
Score = 32.7 bits (71), Expect = 1.5
Identities = 16/78 (20%), Positives = 38/78 (48%)
Frame = -1
Query: 289 LNTLQEKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFD 110
L + + G+K ++ + + GT+ ++ + + G YT + + ++ +++V P D
Sbjct: 999 LEAVSDSGTKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPARVKVEPAVD 1058
Query: 109 SXRERCEGSHSVGQLVCR 56
+ R + G G+ V R
Sbjct: 1059 TSRIKVFGPGIEGKDVFR 1076
>AF191633-1|AAF72339.1| 2602|Homo sapiens filamin protein.
Length = 2602
Score = 32.7 bits (71), Expect = 1.5
Identities = 16/78 (20%), Positives = 38/78 (48%)
Frame = -1
Query: 289 LNTLQEKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFD 110
L + + G+K ++ + + GT+ ++ + + G YT + + ++ +++V P D
Sbjct: 1168 LEAVSDSGTKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPARVKVEPAVD 1227
Query: 109 SXRERCEGSHSVGQLVCR 56
+ R + G G+ V R
Sbjct: 1228 TSRIKVFGPGIEGKDVFR 1245
>AF043045-1|AAC33845.1| 2602|Homo sapiens actin-binding protein
homolog ABP-278 protein.
Length = 2602
Score = 32.7 bits (71), Expect = 1.5
Identities = 16/78 (20%), Positives = 38/78 (48%)
Frame = -1
Query: 289 LNTLQEKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFD 110
L + + G+K ++ + + GT+ ++ + + G YT + + ++ +++V P D
Sbjct: 1168 LEAVSDSGTKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPARVKVEPAVD 1227
Query: 109 SXRERCEGSHSVGQLVCR 56
+ R + G G+ V R
Sbjct: 1228 TSRIKVFGPGIEGKDVFR 1245
>AF042166-1|AAC39842.1| 2602|Homo sapiens beta-filamin protein.
Length = 2602
Score = 32.7 bits (71), Expect = 1.5
Identities = 16/78 (20%), Positives = 38/78 (48%)
Frame = -1
Query: 289 LNTLQEKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFD 110
L + + G+K ++ + + GT+ ++ + + G YT + + ++ +++V P D
Sbjct: 1168 LEAVSDSGTKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPARVKVEPAVD 1227
Query: 109 SXRERCEGSHSVGQLVCR 56
+ R + G G+ V R
Sbjct: 1228 TSRIKVFGPGIEGKDVFR 1245
>AB209889-1|BAD93126.1| 1613|Homo sapiens filamin B, beta (actin
binding protein 278) variant protein.
Length = 1613
Score = 32.7 bits (71), Expect = 1.5
Identities = 16/78 (20%), Positives = 38/78 (48%)
Frame = -1
Query: 289 LNTLQEKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFD 110
L + + G+K ++ + + GT+ ++ + + G YT + + ++ +++V P D
Sbjct: 179 LEAVSDSGTKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPARVKVEPAVD 238
Query: 109 SXRERCEGSHSVGQLVCR 56
+ R + G G+ V R
Sbjct: 239 TSRIKVFGPGIEGKDVFR 256
>AB191258-1|BAD52434.1| 2591|Homo sapiens filamin B protein.
Length = 2591
Score = 32.7 bits (71), Expect = 1.5
Identities = 16/78 (20%), Positives = 38/78 (48%)
Frame = -1
Query: 289 LNTLQEKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFD 110
L + + G+K ++ + + GT+ ++ + + G YT + + ++ +++V P D
Sbjct: 1168 LEAVSDSGTKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPARVKVEPAVD 1227
Query: 109 SXRERCEGSHSVGQLVCR 56
+ R + G G+ V R
Sbjct: 1228 TSRIKVFGPGIEGKDVFR 1245
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 106,260,317
Number of Sequences: 237096
Number of extensions: 2244054
Number of successful extensions: 4565
Number of sequences better than 10.0: 48
Number of HSP's better than 10.0 without gapping: 4192
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4565
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9367263024
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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