Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P07_pT_N20
(740 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
J05262-1|AAA52423.1| 353|Homo sapiens FDPS protein. 194 3e-49
M29863-1|AAA35820.1| 346|Homo sapiens protein ( Human farnesyl ... 193 5e-49
D14697-1|BAA03523.2| 420|Homo sapiens KIAA1293 protein. 193 5e-49
BC010004-1|AAH10004.1| 419|Homo sapiens farnesyl diphosphate sy... 193 5e-49
AL139410-1|CAI12715.1| 419|Homo sapiens farnesyl diphosphate sy... 193 5e-49
Z47055-1|CAA87327.1| 348|Homo sapiens farnesyl pyrophosphate sy... 176 8e-44
BC050292-1|AAH50292.1| 298|Homo sapiens LOC619190 protein protein. 163 4e-40
M87434-1|AAA60607.1| 727|Homo sapiens 71 kDa 2'5' oligoadenylat... 30 7.6
M87284-1|AAA60606.1| 687|Homo sapiens 2'5' oligoadenylate synth... 30 7.6
BC049215-1|AAH49215.1| 687|Homo sapiens 2'-5'-oligoadenylate sy... 30 7.6
>J05262-1|AAA52423.1| 353|Homo sapiens FDPS protein.
Length = 353
Score = 194 bits (473), Expect = 3e-49
Identities = 97/238 (40%), Positives = 139/238 (58%), Gaps = 1/238 (0%)
Frame = -2
Query: 739 MFQAYCIVXDDIMDGSSVRRGMPCWYRRPEVGITCAFNDSLLIHSSLFEFLKTNFRTNPN 560
+ QA+ +V DDIMD S RRG CWY++P VG+ A ND+ L+ + ++ LK R P
Sbjct: 94 LLQAFFLVADDIMDSSLTRRGQTCWYQKPGVGLD-AINDANLLEACIYRLLKLYCREQPY 152
Query: 559 YMKMFELFNETLWRTSMGQHLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYNLPVSL 383
Y+ + ELF ++ ++T +GQ LD +T + D FT R + LP++
Sbjct: 153 YLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAA 212
Query: 382 GLLLAENVDEKIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAV 203
+ +A EK + +A+ I LE+G FQIQDD++D FGD TGK+GTDIQ+ KC+WL V
Sbjct: 213 AMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVV 272
Query: 202 QALQRCTEAQRTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIE 29
Q LQR T Q + K YG E V R+K LYE+L LP ++ E+ Y +I+ IE
Sbjct: 273 QCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIE 330
>M29863-1|AAA35820.1| 346|Homo sapiens protein ( Human farnesyl
pyrophosphate synthetase mRNA (hpt807), 3' end. ).
Length = 346
Score = 193 bits (471), Expect = 5e-49
Identities = 97/238 (40%), Positives = 139/238 (58%), Gaps = 1/238 (0%)
Frame = -2
Query: 739 MFQAYCIVXDDIMDGSSVRRGMPCWYRRPEVGITCAFNDSLLIHSSLFEFLKTNFRTNPN 560
+ QA+ +V DDIMD S RRG CWY++P VG+ A ND+ L+ + ++ LK R P
Sbjct: 87 LLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLD-AINDANLLEACIYRLLKLYCREQPY 145
Query: 559 YMKMFELFNETLWRTSMGQHLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYNLPVSL 383
Y+ + ELF ++ ++T +GQ LD +T + D FT R + LP++
Sbjct: 146 YLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAA 205
Query: 382 GLLLAENVDEKIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAV 203
+ +A EK + +A+ I LE+G FQIQDD++D FGD TGK+GTDIQ+ KC+WL V
Sbjct: 206 AMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVV 265
Query: 202 QALQRCTEAQRTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIE 29
Q LQR T Q + K YG E V R+K LYE+L LP ++ E+ Y +I+ IE
Sbjct: 266 QCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIE 323
>D14697-1|BAA03523.2| 420|Homo sapiens KIAA1293 protein.
Length = 420
Score = 193 bits (471), Expect = 5e-49
Identities = 97/238 (40%), Positives = 139/238 (58%), Gaps = 1/238 (0%)
Frame = -2
Query: 739 MFQAYCIVXDDIMDGSSVRRGMPCWYRRPEVGITCAFNDSLLIHSSLFEFLKTNFRTNPN 560
+ QA+ +V DDIMD S RRG CWY++P VG+ A ND+ L+ + ++ LK R P
Sbjct: 161 LLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLD-AINDANLLEACIYRLLKLYCREQPY 219
Query: 559 YMKMFELFNETLWRTSMGQHLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYNLPVSL 383
Y+ + ELF ++ ++T +GQ LD +T + D FT R + LP++
Sbjct: 220 YLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAA 279
Query: 382 GLLLAENVDEKIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAV 203
+ +A EK + +A+ I LE+G FQIQDD++D FGD TGK+GTDIQ+ KC+WL V
Sbjct: 280 AMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVV 339
Query: 202 QALQRCTEAQRTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIE 29
Q LQR T Q + K YG E V R+K LYE+L LP ++ E+ Y +I+ IE
Sbjct: 340 QCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIE 397
>BC010004-1|AAH10004.1| 419|Homo sapiens farnesyl diphosphate
synthase (farnesyl pyrophosphate synthetase,
dimethylallyl protein.
Length = 419
Score = 193 bits (471), Expect = 5e-49
Identities = 97/238 (40%), Positives = 139/238 (58%), Gaps = 1/238 (0%)
Frame = -2
Query: 739 MFQAYCIVXDDIMDGSSVRRGMPCWYRRPEVGITCAFNDSLLIHSSLFEFLKTNFRTNPN 560
+ QA+ +V DDIMD S RRG CWY++P VG+ A ND+ L+ + ++ LK R P
Sbjct: 160 LLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLD-AINDANLLEACIYRLLKLYCREQPY 218
Query: 559 YMKMFELFNETLWRTSMGQHLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYNLPVSL 383
Y+ + ELF ++ ++T +GQ LD +T + D FT R + LP++
Sbjct: 219 YLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAA 278
Query: 382 GLLLAENVDEKIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAV 203
+ +A EK + +A+ I LE+G FQIQDD++D FGD TGK+GTDIQ+ KC+WL V
Sbjct: 279 AMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVV 338
Query: 202 QALQRCTEAQRTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIE 29
Q LQR T Q + K YG E V R+K LYE+L LP ++ E+ Y +I+ IE
Sbjct: 339 QCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIE 396
>AL139410-1|CAI12715.1| 419|Homo sapiens farnesyl diphosphate
synthase (farnesyl pyrophosphate synthetase,
dimethylallyl protein.
Length = 419
Score = 193 bits (471), Expect = 5e-49
Identities = 97/238 (40%), Positives = 139/238 (58%), Gaps = 1/238 (0%)
Frame = -2
Query: 739 MFQAYCIVXDDIMDGSSVRRGMPCWYRRPEVGITCAFNDSLLIHSSLFEFLKTNFRTNPN 560
+ QA+ +V DDIMD S RRG CWY++P VG+ A ND+ L+ + ++ LK R P
Sbjct: 160 LLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLD-AINDANLLEACIYRLLKLYCREQPY 218
Query: 559 YMKMFELFNETLWRTSMGQHLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYNLPVSL 383
Y+ + ELF ++ ++T +GQ LD +T + D FT R + LP++
Sbjct: 219 YLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAA 278
Query: 382 GLLLAENVDEKIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAV 203
+ +A EK + +A+ I LE+G FQIQDD++D FGD TGK+GTDIQ+ KC+WL V
Sbjct: 279 AMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVV 338
Query: 202 QALQRCTEAQRTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIE 29
Q LQR T Q + K YG E V R+K LYE+L LP ++ E+ Y +I+ IE
Sbjct: 339 QCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIE 396
>Z47055-1|CAA87327.1| 348|Homo sapiens farnesyl pyrophosphate
synthetase like-4 protein.
Length = 348
Score = 176 bits (428), Expect = 8e-44
Identities = 92/238 (38%), Positives = 131/238 (55%), Gaps = 1/238 (0%)
Frame = -2
Query: 739 MFQAYCIVXDDIMDGSSVRRGMPCWYRRPEVGITCAFNDSLLIHSSLFEFLKTNFRTNPN 560
+ QA+ +V DDIMD S RRG CWY++P VG+ A +D+ L+ + ++ LK R P
Sbjct: 89 LLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLD-AIDDANLLEACIYPLLKLYCREQPY 147
Query: 559 YMKMFELFNETLWRTSMGQHLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYNLPVSL 383
Y+ + ELF ++ ++T +GQ LD +T + D FT R LP++
Sbjct: 148 YLNLIELFLQSSYQTEIGQTLDLLTXPQGNVDLVRFTEKRYISIVKYKTALSSSYLPIAA 207
Query: 382 GLLLAENVDEKIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAV 203
V EK + +A I LE+G QIQDD+++ FGD TGK+GTDIQ+ KC L V
Sbjct: 208 AXXXXGIVXEKEHANAXKILLEMGEFSQIQDDYLELFGDPSVTGKIGTDIQDXKCNCLXV 267
Query: 202 QALQRCTEAQRTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIE 29
Q L R T Q + K YG E V R+K LYE+L LP ++ E+ Y +I+ IE
Sbjct: 268 QCLXRATPEQYQILKENYGQKEAEKVPRVKALYEELDLPAVFLQYEEDSYSHIMALIE 325
>BC050292-1|AAH50292.1| 298|Homo sapiens LOC619190 protein protein.
Length = 298
Score = 163 bits (397), Expect = 4e-40
Identities = 86/238 (36%), Positives = 130/238 (54%), Gaps = 1/238 (0%)
Frame = -2
Query: 739 MFQAYCIVXDDIMDGSSVRRGMPCWYRRPEVGITCAFNDSLLIHSSLFEFLKTNFRTNPN 560
+ QA+ +V DDIMD S +G WY++ +G+ A ND++L+ + ++ LK R P
Sbjct: 62 LLQAFFLVADDIMDSSLTCQGQISWYQKLGMGLD-AINDAILLEACIYCLLKLYCREQPY 120
Query: 559 YMKMFELFNETLWRTSMGQHLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYNLPVSL 383
Y+ + ELF + ++T +GQ LD +T + D T R + LPV+
Sbjct: 121 YLNLMELFQQNSYQTEIGQTLDLITTPQGNVDLRRCTEKRHKSVVKYKTAFYSFYLPVAA 180
Query: 382 GLLLAENVDEKIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAV 203
+ ++ D+K + SA+ I LEI FQIQDD++D GD TG+VG D Q+ KC+WL V
Sbjct: 181 AMYMSRMDDKKEHTSAKKILLEIQEFFQIQDDYLDFSGDPSVTGRVGNDFQDNKCSWLVV 240
Query: 202 QALQRCTEAQRTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIE 29
Q L + T Q + K Y E V R+K LYE+L LP ++ EK Y +++ IE
Sbjct: 241 QCLLQATPEQYQILKENYRQKEAEKVARVKALYEELDLPAVFLQYEKDSYSHVMGLIE 298
>M87434-1|AAA60607.1| 727|Homo sapiens 71 kDa 2'5' oligoadenylate
synthetase protein.
Length = 727
Score = 30.3 bits (65), Expect = 7.6
Identities = 12/31 (38%), Positives = 20/31 (64%)
Frame = -3
Query: 246 LVQIYKSANVLGWQFKRCSAVLKHNVQYSKP 154
L+ +YKS+++ G +F C VL+ N S+P
Sbjct: 506 LIDLYKSSDLPGGEFSTCFTVLQRNFIRSRP 536
>M87284-1|AAA60606.1| 687|Homo sapiens 2'5' oligoadenylate
synthetase protein.
Length = 687
Score = 30.3 bits (65), Expect = 7.6
Identities = 12/31 (38%), Positives = 20/31 (64%)
Frame = -3
Query: 246 LVQIYKSANVLGWQFKRCSAVLKHNVQYSKP 154
L+ +YKS+++ G +F C VL+ N S+P
Sbjct: 506 LIDLYKSSDLPGGEFSTCFTVLQRNFIRSRP 536
>BC049215-1|AAH49215.1| 687|Homo sapiens 2'-5'-oligoadenylate
synthetase 2, 69/71kDa protein.
Length = 687
Score = 30.3 bits (65), Expect = 7.6
Identities = 12/31 (38%), Positives = 20/31 (64%)
Frame = -3
Query: 246 LVQIYKSANVLGWQFKRCSAVLKHNVQYSKP 154
L+ +YKS+++ G +F C VL+ N S+P
Sbjct: 506 LIDLYKSSDLPGGEFSTCFTVLQRNFIRSRP 536
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 106,705,351
Number of Sequences: 237096
Number of extensions: 2113181
Number of successful extensions: 4092
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3963
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4078
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8847149012
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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