Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P07_pT_I12
(801 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
J05262-1|AAA52423.1| 353|Homo sapiens FDPS protein. 191 2e-48
M29863-1|AAA35820.1| 346|Homo sapiens protein ( Human farnesyl ... 190 4e-48
D14697-1|BAA03523.2| 420|Homo sapiens KIAA1293 protein. 190 4e-48
BC010004-1|AAH10004.1| 419|Homo sapiens farnesyl diphosphate sy... 190 4e-48
AL139410-1|CAI12715.1| 419|Homo sapiens farnesyl diphosphate sy... 190 4e-48
Z47055-1|CAA87327.1| 348|Homo sapiens farnesyl pyrophosphate sy... 175 2e-43
BC050292-1|AAH50292.1| 298|Homo sapiens LOC619190 protein protein. 159 1e-38
M87434-1|AAA60607.1| 727|Homo sapiens 71 kDa 2'5' oligoadenylat... 30 8.5
M87284-1|AAA60606.1| 687|Homo sapiens 2'5' oligoadenylate synth... 30 8.5
BC049215-1|AAH49215.1| 687|Homo sapiens 2'-5'-oligoadenylate sy... 30 8.5
>J05262-1|AAA52423.1| 353|Homo sapiens FDPS protein.
Length = 353
Score = 191 bits (466), Expect = 2e-48
Identities = 99/260 (38%), Positives = 143/260 (55%), Gaps = 1/260 (0%)
Frame = -2
Query: 800 MFQAYCIVXDDIMDGSSVRRGMPCWYRRPEVGITCAFXDSLLIHSSLFEFXKTNFRTNPN 621
+ QA+ +V DDIMD S RRG CWY++P VG+ A D+ L+ + ++ K R P
Sbjct: 94 LLQAFFLVADDIMDSSLTRRGQTCWYQKPGVGLD-AINDANLLEACIYRLLKLYCREQPY 152
Query: 620 YMKMFELFNETLWRTSMGQHLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYNLPVSL 444
Y+ + ELF ++ ++T +GQ LD +T + D FT R + LP++
Sbjct: 153 YLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAA 212
Query: 443 GLLLAENVDEKIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAV 264
+ +A EK + +A+ I LE+G FQIQDD++D FGD TGK+GTDIQ+ KC+WL V
Sbjct: 213 AMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVV 272
Query: 263 QALQRCTEAQRTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIENI 84
Q LQR T Q + K YG E V R+K LYE+L LP ++ E+ Y +I+ IE
Sbjct: 273 QCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQY 332
Query: 83 PIEAARVLFKKLLDITYNRQ 24
+F L Y R+
Sbjct: 333 AAPLPPAVFLGLARKIYKRR 352
>M29863-1|AAA35820.1| 346|Homo sapiens protein ( Human farnesyl
pyrophosphate synthetase mRNA (hpt807), 3' end. ).
Length = 346
Score = 190 bits (464), Expect = 4e-48
Identities = 99/260 (38%), Positives = 143/260 (55%), Gaps = 1/260 (0%)
Frame = -2
Query: 800 MFQAYCIVXDDIMDGSSVRRGMPCWYRRPEVGITCAFXDSLLIHSSLFEFXKTNFRTNPN 621
+ QA+ +V DDIMD S RRG CWY++P VG+ A D+ L+ + ++ K R P
Sbjct: 87 LLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLD-AINDANLLEACIYRLLKLYCREQPY 145
Query: 620 YMKMFELFNETLWRTSMGQHLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYNLPVSL 444
Y+ + ELF ++ ++T +GQ LD +T + D FT R + LP++
Sbjct: 146 YLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAA 205
Query: 443 GLLLAENVDEKIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAV 264
+ +A EK + +A+ I LE+G FQIQDD++D FGD TGK+GTDIQ+ KC+WL V
Sbjct: 206 AMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVV 265
Query: 263 QALQRCTEAQRTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIENI 84
Q LQR T Q + K YG E V R+K LYE+L LP ++ E+ Y +I+ IE
Sbjct: 266 QCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQY 325
Query: 83 PIEAARVLFKKLLDITYNRQ 24
+F L Y R+
Sbjct: 326 AAPLPPAVFLGLARKIYKRR 345
>D14697-1|BAA03523.2| 420|Homo sapiens KIAA1293 protein.
Length = 420
Score = 190 bits (464), Expect = 4e-48
Identities = 99/260 (38%), Positives = 143/260 (55%), Gaps = 1/260 (0%)
Frame = -2
Query: 800 MFQAYCIVXDDIMDGSSVRRGMPCWYRRPEVGITCAFXDSLLIHSSLFEFXKTNFRTNPN 621
+ QA+ +V DDIMD S RRG CWY++P VG+ A D+ L+ + ++ K R P
Sbjct: 161 LLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLD-AINDANLLEACIYRLLKLYCREQPY 219
Query: 620 YMKMFELFNETLWRTSMGQHLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYNLPVSL 444
Y+ + ELF ++ ++T +GQ LD +T + D FT R + LP++
Sbjct: 220 YLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAA 279
Query: 443 GLLLAENVDEKIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAV 264
+ +A EK + +A+ I LE+G FQIQDD++D FGD TGK+GTDIQ+ KC+WL V
Sbjct: 280 AMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVV 339
Query: 263 QALQRCTEAQRTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIENI 84
Q LQR T Q + K YG E V R+K LYE+L LP ++ E+ Y +I+ IE
Sbjct: 340 QCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQY 399
Query: 83 PIEAARVLFKKLLDITYNRQ 24
+F L Y R+
Sbjct: 400 AAPLPPAVFLGLARKIYKRR 419
>BC010004-1|AAH10004.1| 419|Homo sapiens farnesyl diphosphate
synthase (farnesyl pyrophosphate synthetase,
dimethylallyl protein.
Length = 419
Score = 190 bits (464), Expect = 4e-48
Identities = 99/260 (38%), Positives = 143/260 (55%), Gaps = 1/260 (0%)
Frame = -2
Query: 800 MFQAYCIVXDDIMDGSSVRRGMPCWYRRPEVGITCAFXDSLLIHSSLFEFXKTNFRTNPN 621
+ QA+ +V DDIMD S RRG CWY++P VG+ A D+ L+ + ++ K R P
Sbjct: 160 LLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLD-AINDANLLEACIYRLLKLYCREQPY 218
Query: 620 YMKMFELFNETLWRTSMGQHLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYNLPVSL 444
Y+ + ELF ++ ++T +GQ LD +T + D FT R + LP++
Sbjct: 219 YLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAA 278
Query: 443 GLLLAENVDEKIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAV 264
+ +A EK + +A+ I LE+G FQIQDD++D FGD TGK+GTDIQ+ KC+WL V
Sbjct: 279 AMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVV 338
Query: 263 QALQRCTEAQRTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIENI 84
Q LQR T Q + K YG E V R+K LYE+L LP ++ E+ Y +I+ IE
Sbjct: 339 QCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQY 398
Query: 83 PIEAARVLFKKLLDITYNRQ 24
+F L Y R+
Sbjct: 399 AAPLPPAVFLGLARKIYKRR 418
>AL139410-1|CAI12715.1| 419|Homo sapiens farnesyl diphosphate
synthase (farnesyl pyrophosphate synthetase,
dimethylallyl protein.
Length = 419
Score = 190 bits (464), Expect = 4e-48
Identities = 99/260 (38%), Positives = 143/260 (55%), Gaps = 1/260 (0%)
Frame = -2
Query: 800 MFQAYCIVXDDIMDGSSVRRGMPCWYRRPEVGITCAFXDSLLIHSSLFEFXKTNFRTNPN 621
+ QA+ +V DDIMD S RRG CWY++P VG+ A D+ L+ + ++ K R P
Sbjct: 160 LLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLD-AINDANLLEACIYRLLKLYCREQPY 218
Query: 620 YMKMFELFNETLWRTSMGQHLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYNLPVSL 444
Y+ + ELF ++ ++T +GQ LD +T + D FT R + LP++
Sbjct: 219 YLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAA 278
Query: 443 GLLLAENVDEKIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAV 264
+ +A EK + +A+ I LE+G FQIQDD++D FGD TGK+GTDIQ+ KC+WL V
Sbjct: 279 AMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVV 338
Query: 263 QALQRCTEAQRTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIENI 84
Q LQR T Q + K YG E V R+K LYE+L LP ++ E+ Y +I+ IE
Sbjct: 339 QCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQY 398
Query: 83 PIEAARVLFKKLLDITYNRQ 24
+F L Y R+
Sbjct: 399 AAPLPPAVFLGLARKIYKRR 418
>Z47055-1|CAA87327.1| 348|Homo sapiens farnesyl pyrophosphate
synthetase like-4 protein.
Length = 348
Score = 175 bits (425), Expect = 2e-43
Identities = 95/259 (36%), Positives = 134/259 (51%), Gaps = 1/259 (0%)
Frame = -2
Query: 800 MFQAYCIVXDDIMDGSSVRRGMPCWYRRPEVGITCAFXDSLLIHSSLFEFXKTNFRTNPN 621
+ QA+ +V DDIMD S RRG CWY++P VG+ A D+ L+ + ++ K R P
Sbjct: 89 LLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLD-AIDDANLLEACIYPLLKLYCREQPY 147
Query: 620 YMKMFELFNETLWRTSMGQHLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYNLPVSL 444
Y+ + ELF ++ ++T +GQ LD +T + D FT R LP++
Sbjct: 148 YLNLIELFLQSSYQTEIGQTLDLLTXPQGNVDLVRFTEKRYISIVKYKTALSSSYLPIAA 207
Query: 443 GLLLAENVDEKIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAV 264
V EK + +A I LE+G QIQDD+++ FGD TGK+GTDIQ+ KC L V
Sbjct: 208 AXXXXGIVXEKEHANAXKILLEMGEFSQIQDDYLELFGDPSVTGKIGTDIQDXKCNCLXV 267
Query: 263 QALQRCTEAQRTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIENI 84
Q L R T Q + K YG E V R+K LYE+L LP ++ E+ Y +I+ IE
Sbjct: 268 QCLXRATPEQYQILKENYGQKEAEKVPRVKALYEELDLPAVFLQYEEDSYSHIMALIEQY 327
Query: 83 PIEAARVLFKKLLDITYNR 27
+F L Y R
Sbjct: 328 AAPLPPAVFLGLARQIYKR 346
>BC050292-1|AAH50292.1| 298|Homo sapiens LOC619190 protein protein.
Length = 298
Score = 159 bits (385), Expect = 1e-38
Identities = 84/238 (35%), Positives = 128/238 (53%), Gaps = 1/238 (0%)
Frame = -2
Query: 800 MFQAYCIVXDDIMDGSSVRRGMPCWYRRPEVGITCAFXDSLLIHSSLFEFXKTNFRTNPN 621
+ QA+ +V DDIMD S +G WY++ +G+ A D++L+ + ++ K R P
Sbjct: 62 LLQAFFLVADDIMDSSLTCQGQISWYQKLGMGLD-AINDAILLEACIYCLLKLYCREQPY 120
Query: 620 YMKMFELFNETLWRTSMGQHLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYNLPVSL 444
Y+ + ELF + ++T +GQ LD +T + D T R + LPV+
Sbjct: 121 YLNLMELFQQNSYQTEIGQTLDLITTPQGNVDLRRCTEKRHKSVVKYKTAFYSFYLPVAA 180
Query: 443 GLLLAENVDEKIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAV 264
+ ++ D+K + SA+ I LEI FQIQDD++D GD TG+VG D Q+ KC+WL V
Sbjct: 181 AMYMSRMDDKKEHTSAKKILLEIQEFFQIQDDYLDFSGDPSVTGRVGNDFQDNKCSWLVV 240
Query: 263 QALQRCTEAQRTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIE 90
Q L + T Q + K Y E V R+K LYE+L LP ++ EK Y +++ IE
Sbjct: 241 QCLLQATPEQYQILKENYRQKEAEKVARVKALYEELDLPAVFLQYEKDSYSHVMGLIE 298
>M87434-1|AAA60607.1| 727|Homo sapiens 71 kDa 2'5' oligoadenylate
synthetase protein.
Length = 727
Score = 30.3 bits (65), Expect = 8.5
Identities = 12/31 (38%), Positives = 20/31 (64%)
Frame = -3
Query: 307 LVQIYKSANVLGWQFKRCSAVLKHNVQYSKP 215
L+ +YKS+++ G +F C VL+ N S+P
Sbjct: 506 LIDLYKSSDLPGGEFSTCFTVLQRNFIRSRP 536
>M87284-1|AAA60606.1| 687|Homo sapiens 2'5' oligoadenylate
synthetase protein.
Length = 687
Score = 30.3 bits (65), Expect = 8.5
Identities = 12/31 (38%), Positives = 20/31 (64%)
Frame = -3
Query: 307 LVQIYKSANVLGWQFKRCSAVLKHNVQYSKP 215
L+ +YKS+++ G +F C VL+ N S+P
Sbjct: 506 LIDLYKSSDLPGGEFSTCFTVLQRNFIRSRP 536
>BC049215-1|AAH49215.1| 687|Homo sapiens 2'-5'-oligoadenylate
synthetase 2, 69/71kDa protein.
Length = 687
Score = 30.3 bits (65), Expect = 8.5
Identities = 12/31 (38%), Positives = 20/31 (64%)
Frame = -3
Query: 307 LVQIYKSANVLGWQFKRCSAVLKHNVQYSKP 215
L+ +YKS+++ G +F C VL+ N S+P
Sbjct: 506 LIDLYKSSDLPGGEFSTCFTVLQRNFIRSRP 536
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 112,379,420
Number of Sequences: 237096
Number of extensions: 2220819
Number of successful extensions: 4241
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4114
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4227
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9869080686
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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