Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P07_F_O07
(748 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X57108-1|CAA40392.1| 210|Homo sapiens cerebroside sulfate activ... 97 6e-20
M60258-1|AAA36596.1| 526|Homo sapiens cerebroside sulfate activ... 97 6e-20
M60257-1|AAA36595.1| 524|Homo sapiens cerebroside sulfate activ... 97 6e-20
M60255-1|AAA36594.1| 527|Homo sapiens cerebroside sulfate activ... 97 6e-20
M32221-1|AAA60303.1| 524|Homo sapiens PSAP protein. 97 6e-20
J03077-1|AAA52560.1| 524|Homo sapiens GLBA protein. 97 6e-20
J03015-1|AAB59494.1| 524|Homo sapiens sphingolipid activator pr... 97 6e-20
D00422-1|BAA00321.1| 527|Homo sapiens sphingolipid activator pr... 97 6e-20
BT006849-1|AAP35495.1| 524|Homo sapiens prosaposin (variant Gau... 97 6e-20
BC007612-1|AAH07612.1| 524|Homo sapiens prosaposin (variant Gau... 97 6e-20
BC004275-1|AAH04275.1| 524|Homo sapiens prosaposin (variant Gau... 97 6e-20
BC001503-1|AAH01503.1| 524|Homo sapiens prosaposin (variant Gau... 97 6e-20
AL731541-2|CAI40837.1| 524|Homo sapiens prosaposin (variant Gau... 97 6e-20
AL731541-1|CAI40836.1| 559|Homo sapiens prosaposin (variant Gau... 97 6e-20
AK223290-1|BAD97010.1| 524|Homo sapiens prosaposin (variant Gau... 97 6e-20
AB209776-1|BAD93013.1| 530|Homo sapiens prosaposin variant prot... 97 6e-20
CR456746-1|CAG33027.1| 524|Homo sapiens PSAP protein. 95 2e-19
DQ991252-1|ABJ55983.1| 521|Homo sapiens prosaposin-like protein... 60 8e-09
BC068579-1|AAH68579.1| 543|Homo sapiens PSAPL1 protein protein. 60 8e-09
AK097698-1|BAC05143.1| 241|Homo sapiens protein ( Homo sapiens ... 60 8e-09
BC091483-1|AAH91483.1| 240|Homo sapiens PSAP protein protein. 55 2e-07
M24461-1|AAB59541.1| 381|Homo sapiens pulmonary surfactant-asso... 47 8e-05
AF400074-1|AAK77913.1| 381|Homo sapiens surfactant, pulmonary-a... 47 8e-05
DQ317589-1|ABC59511.1| 147|Homo sapiens truncated surfactant pu... 46 1e-04
J02761-1|AAA60212.1| 381|Homo sapiens pulmonary surfactant-asso... 46 2e-04
BC032785-1|AAH32785.1| 381|Homo sapiens surfactant, pulmonary-a... 46 2e-04
M62840-1|AAA35506.1| 575|Homo sapiens acyloxyacyl hydrolase pro... 44 8e-04
BC025698-1|AAH25698.1| 575|Homo sapiens acyloxyacyl hydrolase (... 44 8e-04
AK223476-1|BAD97196.1| 575|Homo sapiens acyloxyacyl hydrolase p... 44 8e-04
X57107-1|CAA40391.1| 67|Homo sapiens cerebroside sulfate activ... 41 0.004
X05044-2|CAA28715.1| 129|Homo sapiens protein ( Human mRNA (AH2... 34 0.47
M85276-1|AAA59935.1| 145|Homo sapiens NKG5 protein protein. 34 0.47
M16764-1|AAA88099.1| 286|Homo sapiens pulmonary surfactant-asso... 34 0.47
DQ149929-1|ABA06536.1| 916|Homo sapiens serine protease inhibit... 33 1.1
DQ149928-1|ABA06535.1| 1094|Homo sapiens serine protease inhibit... 33 1.1
DQ149927-1|ABA06534.1| 1064|Homo sapiens serine protease inhibit... 33 1.1
AJ228139-1|CAB40839.1| 1064|Homo sapiens LEKTI precursor protein. 33 1.1
AJ391230-1|CAB96877.1| 1064|Homo sapiens serine protease inhibit... 33 1.4
X54101-1|CAA38035.1| 145|Homo sapiens NKG5 product protein. 32 1.9
CR541859-1|CAG46657.1| 145|Homo sapiens GNLY protein. 32 1.9
BC023576-1|AAH23576.1| 145|Homo sapiens granulysin protein. 32 1.9
M19097-1|AAA36628.1| 243|Homo sapiens protein ( Human pulmonary... 32 2.5
BC040609-1|AAH40609.1| 589|Homo sapiens SUMO1/sentrin/SMT3 spec... 32 2.5
AY584611-1|AAS91740.1| 2367|Homo sapiens GPR158-like 1 receptor ... 32 2.5
AL834380-1|CAD39043.1| 587|Homo sapiens hypothetical protein pr... 32 2.5
AK027599-1|BAB55222.1| 589|Homo sapiens protein ( Homo sapiens ... 32 2.5
AF151697-1|AAG15309.2| 590|Homo sapiens sentrin-specific protea... 32 2.5
AB037752-1|BAA92569.2| 589|Homo sapiens KIAA1331 protein protein. 32 2.5
>X57108-1|CAA40392.1| 210|Homo sapiens cerebroside sulfate
activator protein.
Length = 210
Score = 97.1 bits (231), Expect = 6e-20
Identities = 51/168 (30%), Positives = 80/168 (47%), Gaps = 5/168 (2%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSAECDQFVEKYADLVISLLAQ 242
C +CEF++KE+ I + + EI A +C +PKS+S EC + V+ Y ++S+L +
Sbjct: 12 CEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLE 71
Query: 243 ELDPSEVCEELKLCK----PESXXXXXXXXXXXXCAVCETVVMAVKKVLKNEKLDRNIVH 410
E+ P VC L LC P C VC+ +V + + L+ + I+
Sbjct: 72 EVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILA 131
Query: 411 IIEKSCGLLPAKYNTRCYAMLEVYGESIIH-LIEEFGAKGVCQRIGFC 551
+EK C LP Y +C + Y +I L+E VC +IG C
Sbjct: 132 ALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 179
Score = 55.2 bits (127), Expect = 2e-07
Identities = 27/93 (29%), Positives = 47/93 (50%)
Frame = +3
Query: 6 LPDATVNGRRVSHKSQSNVCVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSA 185
LP TV+ V+ C +C+ ++ +D ++ EI A+ C +P
Sbjct: 90 LPALTVH---VTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQK 146
Query: 186 ECDQFVEKYADLVISLLAQELDPSEVCEELKLC 284
+CDQFV +Y ++I +L + +DPS VC ++ C
Sbjct: 147 QCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 179
>M60258-1|AAA36596.1| 526|Homo sapiens cerebroside sulfate
activator protein protein.
Length = 526
Score = 97.1 bits (231), Expect = 6e-20
Identities = 51/168 (30%), Positives = 80/168 (47%), Gaps = 5/168 (2%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSAECDQFVEKYADLVISLLAQ 242
C +CEF++KE+ I + + EI A +C +PKS+S EC + V+ Y ++S+L +
Sbjct: 317 CEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLE 376
Query: 243 ELDPSEVCEELKLCK----PESXXXXXXXXXXXXCAVCETVVMAVKKVLKNEKLDRNIVH 410
E+ P VC L LC P C VC+ +V + + L+ + I+
Sbjct: 377 EVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILA 436
Query: 411 IIEKSCGLLPAKYNTRCYAMLEVYGESIIH-LIEEFGAKGVCQRIGFC 551
+EK C LP Y +C + Y +I L+E VC +IG C
Sbjct: 437 ALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 484
Score = 55.2 bits (127), Expect = 2e-07
Identities = 27/93 (29%), Positives = 47/93 (50%)
Frame = +3
Query: 6 LPDATVNGRRVSHKSQSNVCVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSA 185
LP TV+ V+ C +C+ ++ +D ++ EI A+ C +P
Sbjct: 395 LPALTVH---VTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQK 451
Query: 186 ECDQFVEKYADLVISLLAQELDPSEVCEELKLC 284
+CDQFV +Y ++I +L + +DPS VC ++ C
Sbjct: 452 QCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 484
Score = 53.6 bits (123), Expect = 7e-07
Identities = 24/77 (31%), Positives = 43/77 (55%), Gaps = 2/77 (2%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPK-SVSAECDQFVEKYADLVISLLA 239
C +C+ V+ D +KD ++EI + C +PK ++SA C + V+ Y +++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 240 QELD-PSEVCEELKLCK 287
E+ P EVC L LC+
Sbjct: 123 GEMSRPGEVCSALNLCE 139
Score = 39.5 bits (88), Expect = 0.013
Identities = 23/91 (25%), Positives = 43/91 (47%), Gaps = 3/91 (3%)
Frame = +3
Query: 333 CAVCETVVMAVKKVLKNEKLDRNIVHIIEKSCGLLP-AKYNTRCYAMLEVYGESIIHLIE 509
C +C+ VV A +LK+ + I+ +EK+C LP + C +++ Y I+ +I+
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 510 -EFGAKG-VCQRIGFCGRTETAYVRMYREKR 596
E G VC + C + + +K+
Sbjct: 123 GEMSRPGEVCSALNLCESLQKHLAELNHQKQ 153
>M60257-1|AAA36595.1| 524|Homo sapiens cerebroside sulfate
activator protein protein.
Length = 524
Score = 97.1 bits (231), Expect = 6e-20
Identities = 51/168 (30%), Positives = 80/168 (47%), Gaps = 5/168 (2%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSAECDQFVEKYADLVISLLAQ 242
C +CEF++KE+ I + + EI A +C +PKS+S EC + V+ Y ++S+L +
Sbjct: 315 CEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLE 374
Query: 243 ELDPSEVCEELKLCK----PESXXXXXXXXXXXXCAVCETVVMAVKKVLKNEKLDRNIVH 410
E+ P VC L LC P C VC+ +V + + L+ + I+
Sbjct: 375 EVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILA 434
Query: 411 IIEKSCGLLPAKYNTRCYAMLEVYGESIIH-LIEEFGAKGVCQRIGFC 551
+EK C LP Y +C + Y +I L+E VC +IG C
Sbjct: 435 ALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 482
Score = 55.2 bits (127), Expect = 2e-07
Identities = 27/93 (29%), Positives = 47/93 (50%)
Frame = +3
Query: 6 LPDATVNGRRVSHKSQSNVCVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSA 185
LP TV+ V+ C +C+ ++ +D ++ EI A+ C +P
Sbjct: 393 LPALTVH---VTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQK 449
Query: 186 ECDQFVEKYADLVISLLAQELDPSEVCEELKLC 284
+CDQFV +Y ++I +L + +DPS VC ++ C
Sbjct: 450 QCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 482
Score = 53.6 bits (123), Expect = 7e-07
Identities = 24/77 (31%), Positives = 43/77 (55%), Gaps = 2/77 (2%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPK-SVSAECDQFVEKYADLVISLLA 239
C +C+ V+ D +KD ++EI + C +PK ++SA C + V+ Y +++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 240 QELD-PSEVCEELKLCK 287
E+ P EVC L LC+
Sbjct: 123 GEMSRPGEVCSALNLCE 139
Score = 39.5 bits (88), Expect = 0.013
Identities = 23/91 (25%), Positives = 43/91 (47%), Gaps = 3/91 (3%)
Frame = +3
Query: 333 CAVCETVVMAVKKVLKNEKLDRNIVHIIEKSCGLLP-AKYNTRCYAMLEVYGESIIHLIE 509
C +C+ VV A +LK+ + I+ +EK+C LP + C +++ Y I+ +I+
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 510 -EFGAKG-VCQRIGFCGRTETAYVRMYREKR 596
E G VC + C + + +K+
Sbjct: 123 GEMSRPGEVCSALNLCESLQKHLAELNHQKQ 153
>M60255-1|AAA36594.1| 527|Homo sapiens cerebroside sulfate
activator protein protein.
Length = 527
Score = 97.1 bits (231), Expect = 6e-20
Identities = 51/168 (30%), Positives = 80/168 (47%), Gaps = 5/168 (2%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSAECDQFVEKYADLVISLLAQ 242
C +CEF++KE+ I + + EI A +C +PKS+S EC + V+ Y ++S+L +
Sbjct: 318 CEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLE 377
Query: 243 ELDPSEVCEELKLCK----PESXXXXXXXXXXXXCAVCETVVMAVKKVLKNEKLDRNIVH 410
E+ P VC L LC P C VC+ +V + + L+ + I+
Sbjct: 378 EVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILA 437
Query: 411 IIEKSCGLLPAKYNTRCYAMLEVYGESIIH-LIEEFGAKGVCQRIGFC 551
+EK C LP Y +C + Y +I L+E VC +IG C
Sbjct: 438 ALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 485
Score = 55.2 bits (127), Expect = 2e-07
Identities = 27/93 (29%), Positives = 47/93 (50%)
Frame = +3
Query: 6 LPDATVNGRRVSHKSQSNVCVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSA 185
LP TV+ V+ C +C+ ++ +D ++ EI A+ C +P
Sbjct: 396 LPALTVH---VTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQK 452
Query: 186 ECDQFVEKYADLVISLLAQELDPSEVCEELKLC 284
+CDQFV +Y ++I +L + +DPS VC ++ C
Sbjct: 453 QCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 485
Score = 53.6 bits (123), Expect = 7e-07
Identities = 24/77 (31%), Positives = 43/77 (55%), Gaps = 2/77 (2%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPK-SVSAECDQFVEKYADLVISLLA 239
C +C+ V+ D +KD ++EI + C +PK ++SA C + V+ Y +++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 240 QELD-PSEVCEELKLCK 287
E+ P EVC L LC+
Sbjct: 123 GEMSRPGEVCSALNLCE 139
Score = 39.5 bits (88), Expect = 0.013
Identities = 23/91 (25%), Positives = 43/91 (47%), Gaps = 3/91 (3%)
Frame = +3
Query: 333 CAVCETVVMAVKKVLKNEKLDRNIVHIIEKSCGLLP-AKYNTRCYAMLEVYGESIIHLIE 509
C +C+ VV A +LK+ + I+ +EK+C LP + C +++ Y I+ +I+
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 510 -EFGAKG-VCQRIGFCGRTETAYVRMYREKR 596
E G VC + C + + +K+
Sbjct: 123 GEMSRPGEVCSALNLCESLQKHLAELNHQKQ 153
>M32221-1|AAA60303.1| 524|Homo sapiens PSAP protein.
Length = 524
Score = 97.1 bits (231), Expect = 6e-20
Identities = 51/168 (30%), Positives = 80/168 (47%), Gaps = 5/168 (2%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSAECDQFVEKYADLVISLLAQ 242
C +CEF++KE+ I + + EI A +C +PKS+S EC + V+ Y ++S+L +
Sbjct: 315 CEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLE 374
Query: 243 ELDPSEVCEELKLCK----PESXXXXXXXXXXXXCAVCETVVMAVKKVLKNEKLDRNIVH 410
E+ P VC L LC P C VC+ +V + + L+ + I+
Sbjct: 375 EVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILA 434
Query: 411 IIEKSCGLLPAKYNTRCYAMLEVYGESIIH-LIEEFGAKGVCQRIGFC 551
+EK C LP Y +C + Y +I L+E VC +IG C
Sbjct: 435 ALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 482
Score = 55.2 bits (127), Expect = 2e-07
Identities = 27/93 (29%), Positives = 47/93 (50%)
Frame = +3
Query: 6 LPDATVNGRRVSHKSQSNVCVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSA 185
LP TV+ V+ C +C+ ++ +D ++ EI A+ C +P
Sbjct: 393 LPALTVH---VTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQK 449
Query: 186 ECDQFVEKYADLVISLLAQELDPSEVCEELKLC 284
+CDQFV +Y ++I +L + +DPS VC ++ C
Sbjct: 450 QCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 482
Score = 53.6 bits (123), Expect = 7e-07
Identities = 24/77 (31%), Positives = 43/77 (55%), Gaps = 2/77 (2%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPK-SVSAECDQFVEKYADLVISLLA 239
C +C+ V+ D +KD ++EI + C +PK ++SA C + V+ Y +++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 240 QELD-PSEVCEELKLCK 287
E+ P EVC L LC+
Sbjct: 123 GEMSRPGEVCSALNLCE 139
Score = 39.5 bits (88), Expect = 0.013
Identities = 23/91 (25%), Positives = 43/91 (47%), Gaps = 3/91 (3%)
Frame = +3
Query: 333 CAVCETVVMAVKKVLKNEKLDRNIVHIIEKSCGLLP-AKYNTRCYAMLEVYGESIIHLIE 509
C +C+ VV A +LK+ + I+ +EK+C LP + C +++ Y I+ +I+
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 510 -EFGAKG-VCQRIGFCGRTETAYVRMYREKR 596
E G VC + C + + +K+
Sbjct: 123 GEMSRPGEVCSALNLCESLQKHLAELNHQKQ 153
Score = 30.3 bits (65), Expect = 7.7
Identities = 16/74 (21%), Positives = 31/74 (41%), Gaps = 1/74 (1%)
Frame = +3
Query: 333 CAVCETVVMAVKKVLK-NEKLDRNIVHIIEKSCGLLPAKYNTRCYAMLEVYGESIIHLIE 509
C C +V ++ ++ N + +V +++ C L C + Y E I ++
Sbjct: 198 CQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAIQMMM 257
Query: 510 EFGAKGVCQRIGFC 551
K +C +GFC
Sbjct: 258 HMQPKEICALVGFC 271
>J03077-1|AAA52560.1| 524|Homo sapiens GLBA protein.
Length = 524
Score = 97.1 bits (231), Expect = 6e-20
Identities = 51/168 (30%), Positives = 80/168 (47%), Gaps = 5/168 (2%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSAECDQFVEKYADLVISLLAQ 242
C +CEF++KE+ I + + EI A +C +PKS+S EC + V+ Y ++S+L +
Sbjct: 315 CEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLE 374
Query: 243 ELDPSEVCEELKLCK----PESXXXXXXXXXXXXCAVCETVVMAVKKVLKNEKLDRNIVH 410
E+ P VC L LC P C VC+ +V + + L+ + I+
Sbjct: 375 EVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILA 434
Query: 411 IIEKSCGLLPAKYNTRCYAMLEVYGESIIH-LIEEFGAKGVCQRIGFC 551
+EK C LP Y +C + Y +I L+E VC +IG C
Sbjct: 435 ALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 482
Score = 55.2 bits (127), Expect = 2e-07
Identities = 27/93 (29%), Positives = 47/93 (50%)
Frame = +3
Query: 6 LPDATVNGRRVSHKSQSNVCVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSA 185
LP TV+ V+ C +C+ ++ +D ++ EI A+ C +P
Sbjct: 393 LPALTVH---VTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQK 449
Query: 186 ECDQFVEKYADLVISLLAQELDPSEVCEELKLC 284
+CDQFV +Y ++I +L + +DPS VC ++ C
Sbjct: 450 QCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 482
Score = 53.6 bits (123), Expect = 7e-07
Identities = 24/77 (31%), Positives = 43/77 (55%), Gaps = 2/77 (2%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPK-SVSAECDQFVEKYADLVISLLA 239
C +C+ V+ D +KD ++EI + C +PK ++SA C + V+ Y +++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 240 QELD-PSEVCEELKLCK 287
E+ P EVC L LC+
Sbjct: 123 GEMSRPGEVCSALNLCE 139
Score = 39.5 bits (88), Expect = 0.013
Identities = 23/91 (25%), Positives = 43/91 (47%), Gaps = 3/91 (3%)
Frame = +3
Query: 333 CAVCETVVMAVKKVLKNEKLDRNIVHIIEKSCGLLP-AKYNTRCYAMLEVYGESIIHLIE 509
C +C+ VV A +LK+ + I+ +EK+C LP + C +++ Y I+ +I+
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 510 -EFGAKG-VCQRIGFCGRTETAYVRMYREKR 596
E G VC + C + + +K+
Sbjct: 123 GEMSRPGEVCSALNLCESLQKHLAELNHQKQ 153
Score = 30.3 bits (65), Expect = 7.7
Identities = 16/74 (21%), Positives = 31/74 (41%), Gaps = 1/74 (1%)
Frame = +3
Query: 333 CAVCETVVMAVKKVLK-NEKLDRNIVHIIEKSCGLLPAKYNTRCYAMLEVYGESIIHLIE 509
C C +V ++ ++ N + +V +++ C L C + Y E I ++
Sbjct: 198 CQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAIQMMM 257
Query: 510 EFGAKGVCQRIGFC 551
K +C +GFC
Sbjct: 258 HMQPKEICALVGFC 271
>J03015-1|AAB59494.1| 524|Homo sapiens sphingolipid activator
precursor protein.
Length = 524
Score = 97.1 bits (231), Expect = 6e-20
Identities = 51/168 (30%), Positives = 80/168 (47%), Gaps = 5/168 (2%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSAECDQFVEKYADLVISLLAQ 242
C +CEF++KE+ I + + EI A +C +PKS+S EC + V+ Y ++S+L +
Sbjct: 315 CEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLE 374
Query: 243 ELDPSEVCEELKLCK----PESXXXXXXXXXXXXCAVCETVVMAVKKVLKNEKLDRNIVH 410
E+ P VC L LC P C VC+ +V + + L+ + I+
Sbjct: 375 EVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILA 434
Query: 411 IIEKSCGLLPAKYNTRCYAMLEVYGESIIH-LIEEFGAKGVCQRIGFC 551
+EK C LP Y +C + Y +I L+E VC +IG C
Sbjct: 435 ALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 482
Score = 55.2 bits (127), Expect = 2e-07
Identities = 27/93 (29%), Positives = 47/93 (50%)
Frame = +3
Query: 6 LPDATVNGRRVSHKSQSNVCVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSA 185
LP TV+ V+ C +C+ ++ +D ++ EI A+ C +P
Sbjct: 393 LPALTVH---VTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQK 449
Query: 186 ECDQFVEKYADLVISLLAQELDPSEVCEELKLC 284
+CDQFV +Y ++I +L + +DPS VC ++ C
Sbjct: 450 QCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 482
Score = 53.6 bits (123), Expect = 7e-07
Identities = 24/77 (31%), Positives = 43/77 (55%), Gaps = 2/77 (2%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPK-SVSAECDQFVEKYADLVISLLA 239
C +C+ V+ D +KD ++EI + C +PK ++SA C + V+ Y +++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 240 QELD-PSEVCEELKLCK 287
E+ P EVC L LC+
Sbjct: 123 GEMSRPGEVCSALNLCE 139
Score = 39.5 bits (88), Expect = 0.013
Identities = 23/91 (25%), Positives = 43/91 (47%), Gaps = 3/91 (3%)
Frame = +3
Query: 333 CAVCETVVMAVKKVLKNEKLDRNIVHIIEKSCGLLP-AKYNTRCYAMLEVYGESIIHLIE 509
C +C+ VV A +LK+ + I+ +EK+C LP + C +++ Y I+ +I+
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 510 -EFGAKG-VCQRIGFCGRTETAYVRMYREKR 596
E G VC + C + + +K+
Sbjct: 123 GEMSRPGEVCSALNLCESLQKHLAELNHQKQ 153
Score = 30.3 bits (65), Expect = 7.7
Identities = 16/74 (21%), Positives = 31/74 (41%), Gaps = 1/74 (1%)
Frame = +3
Query: 333 CAVCETVVMAVKKVLK-NEKLDRNIVHIIEKSCGLLPAKYNTRCYAMLEVYGESIIHLIE 509
C C +V ++ ++ N + +V +++ C L C + Y E I ++
Sbjct: 198 CQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAIQMMM 257
Query: 510 EFGAKGVCQRIGFC 551
K +C +GFC
Sbjct: 258 HMQPKEICALVGFC 271
>D00422-1|BAA00321.1| 527|Homo sapiens sphingolipid activator
proteins protein.
Length = 527
Score = 97.1 bits (231), Expect = 6e-20
Identities = 51/168 (30%), Positives = 80/168 (47%), Gaps = 5/168 (2%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSAECDQFVEKYADLVISLLAQ 242
C +CEF++KE+ I + + EI A +C +PKS+S EC + V+ Y ++S+L +
Sbjct: 318 CEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLE 377
Query: 243 ELDPSEVCEELKLCK----PESXXXXXXXXXXXXCAVCETVVMAVKKVLKNEKLDRNIVH 410
E+ P VC L LC P C VC+ +V + + L+ + I+
Sbjct: 378 EVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILA 437
Query: 411 IIEKSCGLLPAKYNTRCYAMLEVYGESIIH-LIEEFGAKGVCQRIGFC 551
+EK C LP Y +C + Y +I L+E VC +IG C
Sbjct: 438 ALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 485
Score = 55.2 bits (127), Expect = 2e-07
Identities = 27/93 (29%), Positives = 47/93 (50%)
Frame = +3
Query: 6 LPDATVNGRRVSHKSQSNVCVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSA 185
LP TV+ V+ C +C+ ++ +D ++ EI A+ C +P
Sbjct: 396 LPALTVH---VTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQK 452
Query: 186 ECDQFVEKYADLVISLLAQELDPSEVCEELKLC 284
+CDQFV +Y ++I +L + +DPS VC ++ C
Sbjct: 453 QCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 485
Score = 53.6 bits (123), Expect = 7e-07
Identities = 24/77 (31%), Positives = 43/77 (55%), Gaps = 2/77 (2%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPK-SVSAECDQFVEKYADLVISLLA 239
C +C+ V+ D +KD ++EI + C +PK ++SA C + V+ Y +++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 240 QELD-PSEVCEELKLCK 287
E+ P EVC L LC+
Sbjct: 123 GEMSRPGEVCSALNLCE 139
Score = 39.5 bits (88), Expect = 0.013
Identities = 23/91 (25%), Positives = 43/91 (47%), Gaps = 3/91 (3%)
Frame = +3
Query: 333 CAVCETVVMAVKKVLKNEKLDRNIVHIIEKSCGLLP-AKYNTRCYAMLEVYGESIIHLIE 509
C +C+ VV A +LK+ + I+ +EK+C LP + C +++ Y I+ +I+
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 510 -EFGAKG-VCQRIGFCGRTETAYVRMYREKR 596
E G VC + C + + +K+
Sbjct: 123 GEMSRPGEVCSALNLCESLQKHLAELNHQKQ 153
>BT006849-1|AAP35495.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 97.1 bits (231), Expect = 6e-20
Identities = 51/168 (30%), Positives = 80/168 (47%), Gaps = 5/168 (2%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSAECDQFVEKYADLVISLLAQ 242
C +CEF++KE+ I + + EI A +C +PKS+S EC + V+ Y ++S+L +
Sbjct: 315 CEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLE 374
Query: 243 ELDPSEVCEELKLCK----PESXXXXXXXXXXXXCAVCETVVMAVKKVLKNEKLDRNIVH 410
E+ P VC L LC P C VC+ +V + + L+ + I+
Sbjct: 375 EVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILA 434
Query: 411 IIEKSCGLLPAKYNTRCYAMLEVYGESIIH-LIEEFGAKGVCQRIGFC 551
+EK C LP Y +C + Y +I L+E VC +IG C
Sbjct: 435 ALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 482
Score = 55.2 bits (127), Expect = 2e-07
Identities = 27/93 (29%), Positives = 47/93 (50%)
Frame = +3
Query: 6 LPDATVNGRRVSHKSQSNVCVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSA 185
LP TV+ V+ C +C+ ++ +D ++ EI A+ C +P
Sbjct: 393 LPALTVH---VTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQK 449
Query: 186 ECDQFVEKYADLVISLLAQELDPSEVCEELKLC 284
+CDQFV +Y ++I +L + +DPS VC ++ C
Sbjct: 450 QCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 482
Score = 53.6 bits (123), Expect = 7e-07
Identities = 24/77 (31%), Positives = 43/77 (55%), Gaps = 2/77 (2%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPK-SVSAECDQFVEKYADLVISLLA 239
C +C+ V+ D +KD ++EI + C +PK ++SA C + V+ Y +++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 240 QELD-PSEVCEELKLCK 287
E+ P EVC L LC+
Sbjct: 123 GEMSRPGEVCSALNLCE 139
Score = 39.5 bits (88), Expect = 0.013
Identities = 23/91 (25%), Positives = 43/91 (47%), Gaps = 3/91 (3%)
Frame = +3
Query: 333 CAVCETVVMAVKKVLKNEKLDRNIVHIIEKSCGLLP-AKYNTRCYAMLEVYGESIIHLIE 509
C +C+ VV A +LK+ + I+ +EK+C LP + C +++ Y I+ +I+
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 510 -EFGAKG-VCQRIGFCGRTETAYVRMYREKR 596
E G VC + C + + +K+
Sbjct: 123 GEMSRPGEVCSALNLCESLQKHLAELNHQKQ 153
Score = 30.3 bits (65), Expect = 7.7
Identities = 16/74 (21%), Positives = 31/74 (41%), Gaps = 1/74 (1%)
Frame = +3
Query: 333 CAVCETVVMAVKKVLK-NEKLDRNIVHIIEKSCGLLPAKYNTRCYAMLEVYGESIIHLIE 509
C C +V ++ ++ N + +V +++ C L C + Y E I ++
Sbjct: 198 CQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAIQMMM 257
Query: 510 EFGAKGVCQRIGFC 551
K +C +GFC
Sbjct: 258 HMQPKEICALVGFC 271
>BC007612-1|AAH07612.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 97.1 bits (231), Expect = 6e-20
Identities = 51/168 (30%), Positives = 80/168 (47%), Gaps = 5/168 (2%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSAECDQFVEKYADLVISLLAQ 242
C +CEF++KE+ I + + EI A +C +PKS+S EC + V+ Y ++S+L +
Sbjct: 315 CEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLE 374
Query: 243 ELDPSEVCEELKLCK----PESXXXXXXXXXXXXCAVCETVVMAVKKVLKNEKLDRNIVH 410
E+ P VC L LC P C VC+ +V + + L+ + I+
Sbjct: 375 EVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILA 434
Query: 411 IIEKSCGLLPAKYNTRCYAMLEVYGESIIH-LIEEFGAKGVCQRIGFC 551
+EK C LP Y +C + Y +I L+E VC +IG C
Sbjct: 435 ALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 482
Score = 55.2 bits (127), Expect = 2e-07
Identities = 27/93 (29%), Positives = 47/93 (50%)
Frame = +3
Query: 6 LPDATVNGRRVSHKSQSNVCVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSA 185
LP TV+ V+ C +C+ ++ +D ++ EI A+ C +P
Sbjct: 393 LPALTVH---VTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQK 449
Query: 186 ECDQFVEKYADLVISLLAQELDPSEVCEELKLC 284
+CDQFV +Y ++I +L + +DPS VC ++ C
Sbjct: 450 QCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 482
Score = 53.6 bits (123), Expect = 7e-07
Identities = 24/77 (31%), Positives = 43/77 (55%), Gaps = 2/77 (2%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPK-SVSAECDQFVEKYADLVISLLA 239
C +C+ V+ D +KD ++EI + C +PK ++SA C + V+ Y +++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 240 QELD-PSEVCEELKLCK 287
E+ P EVC L LC+
Sbjct: 123 GEMSRPGEVCSALNLCE 139
Score = 39.5 bits (88), Expect = 0.013
Identities = 23/91 (25%), Positives = 43/91 (47%), Gaps = 3/91 (3%)
Frame = +3
Query: 333 CAVCETVVMAVKKVLKNEKLDRNIVHIIEKSCGLLP-AKYNTRCYAMLEVYGESIIHLIE 509
C +C+ VV A +LK+ + I+ +EK+C LP + C +++ Y I+ +I+
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 510 -EFGAKG-VCQRIGFCGRTETAYVRMYREKR 596
E G VC + C + + +K+
Sbjct: 123 GEMSRPGEVCSALNLCESLQKHLAELNHQKQ 153
Score = 30.3 bits (65), Expect = 7.7
Identities = 16/74 (21%), Positives = 31/74 (41%), Gaps = 1/74 (1%)
Frame = +3
Query: 333 CAVCETVVMAVKKVLK-NEKLDRNIVHIIEKSCGLLPAKYNTRCYAMLEVYGESIIHLIE 509
C C +V ++ ++ N + +V +++ C L C + Y E I ++
Sbjct: 198 CQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAIQMMM 257
Query: 510 EFGAKGVCQRIGFC 551
K +C +GFC
Sbjct: 258 HMQPKEICALVGFC 271
>BC004275-1|AAH04275.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 97.1 bits (231), Expect = 6e-20
Identities = 51/168 (30%), Positives = 80/168 (47%), Gaps = 5/168 (2%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSAECDQFVEKYADLVISLLAQ 242
C +CEF++KE+ I + + EI A +C +PKS+S EC + V+ Y ++S+L +
Sbjct: 315 CEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLE 374
Query: 243 ELDPSEVCEELKLCK----PESXXXXXXXXXXXXCAVCETVVMAVKKVLKNEKLDRNIVH 410
E+ P VC L LC P C VC+ +V + + L+ + I+
Sbjct: 375 EVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILA 434
Query: 411 IIEKSCGLLPAKYNTRCYAMLEVYGESIIH-LIEEFGAKGVCQRIGFC 551
+EK C LP Y +C + Y +I L+E VC +IG C
Sbjct: 435 ALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 482
Score = 55.2 bits (127), Expect = 2e-07
Identities = 27/93 (29%), Positives = 47/93 (50%)
Frame = +3
Query: 6 LPDATVNGRRVSHKSQSNVCVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSA 185
LP TV+ V+ C +C+ ++ +D ++ EI A+ C +P
Sbjct: 393 LPALTVH---VTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQK 449
Query: 186 ECDQFVEKYADLVISLLAQELDPSEVCEELKLC 284
+CDQFV +Y ++I +L + +DPS VC ++ C
Sbjct: 450 QCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 482
Score = 53.6 bits (123), Expect = 7e-07
Identities = 24/77 (31%), Positives = 43/77 (55%), Gaps = 2/77 (2%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPK-SVSAECDQFVEKYADLVISLLA 239
C +C+ V+ D +KD ++EI + C +PK ++SA C + V+ Y +++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 240 QELD-PSEVCEELKLCK 287
E+ P EVC L LC+
Sbjct: 123 GEMSRPGEVCSALNLCE 139
Score = 39.5 bits (88), Expect = 0.013
Identities = 23/91 (25%), Positives = 43/91 (47%), Gaps = 3/91 (3%)
Frame = +3
Query: 333 CAVCETVVMAVKKVLKNEKLDRNIVHIIEKSCGLLP-AKYNTRCYAMLEVYGESIIHLIE 509
C +C+ VV A +LK+ + I+ +EK+C LP + C +++ Y I+ +I+
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 510 -EFGAKG-VCQRIGFCGRTETAYVRMYREKR 596
E G VC + C + + +K+
Sbjct: 123 GEMSRPGEVCSALNLCESLQKHLAELNHQKQ 153
Score = 30.3 bits (65), Expect = 7.7
Identities = 16/74 (21%), Positives = 31/74 (41%), Gaps = 1/74 (1%)
Frame = +3
Query: 333 CAVCETVVMAVKKVLK-NEKLDRNIVHIIEKSCGLLPAKYNTRCYAMLEVYGESIIHLIE 509
C C +V ++ ++ N + +V +++ C L C + Y E I ++
Sbjct: 198 CQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAIQMMM 257
Query: 510 EFGAKGVCQRIGFC 551
K +C +GFC
Sbjct: 258 HMQPKEICALVGFC 271
>BC001503-1|AAH01503.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 97.1 bits (231), Expect = 6e-20
Identities = 51/168 (30%), Positives = 80/168 (47%), Gaps = 5/168 (2%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSAECDQFVEKYADLVISLLAQ 242
C +CEF++KE+ I + + EI A +C +PKS+S EC + V+ Y ++S+L +
Sbjct: 315 CEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLE 374
Query: 243 ELDPSEVCEELKLCK----PESXXXXXXXXXXXXCAVCETVVMAVKKVLKNEKLDRNIVH 410
E+ P VC L LC P C VC+ +V + + L+ + I+
Sbjct: 375 EVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILA 434
Query: 411 IIEKSCGLLPAKYNTRCYAMLEVYGESIIH-LIEEFGAKGVCQRIGFC 551
+EK C LP Y +C + Y +I L+E VC +IG C
Sbjct: 435 ALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 482
Score = 55.2 bits (127), Expect = 2e-07
Identities = 27/93 (29%), Positives = 47/93 (50%)
Frame = +3
Query: 6 LPDATVNGRRVSHKSQSNVCVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSA 185
LP TV+ V+ C +C+ ++ +D ++ EI A+ C +P
Sbjct: 393 LPALTVH---VTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQK 449
Query: 186 ECDQFVEKYADLVISLLAQELDPSEVCEELKLC 284
+CDQFV +Y ++I +L + +DPS VC ++ C
Sbjct: 450 QCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 482
Score = 53.6 bits (123), Expect = 7e-07
Identities = 24/77 (31%), Positives = 43/77 (55%), Gaps = 2/77 (2%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPK-SVSAECDQFVEKYADLVISLLA 239
C +C+ V+ D +KD ++EI + C +PK ++SA C + V+ Y +++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 240 QELD-PSEVCEELKLCK 287
E+ P EVC L LC+
Sbjct: 123 GEMSRPGEVCSALNLCE 139
Score = 39.5 bits (88), Expect = 0.013
Identities = 23/91 (25%), Positives = 43/91 (47%), Gaps = 3/91 (3%)
Frame = +3
Query: 333 CAVCETVVMAVKKVLKNEKLDRNIVHIIEKSCGLLP-AKYNTRCYAMLEVYGESIIHLIE 509
C +C+ VV A +LK+ + I+ +EK+C LP + C +++ Y I+ +I+
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 510 -EFGAKG-VCQRIGFCGRTETAYVRMYREKR 596
E G VC + C + + +K+
Sbjct: 123 GEMSRPGEVCSALNLCESLQKHLAELNHQKQ 153
Score = 30.3 bits (65), Expect = 7.7
Identities = 16/74 (21%), Positives = 31/74 (41%), Gaps = 1/74 (1%)
Frame = +3
Query: 333 CAVCETVVMAVKKVLK-NEKLDRNIVHIIEKSCGLLPAKYNTRCYAMLEVYGESIIHLIE 509
C C +V ++ ++ N + +V +++ C L C + Y E I ++
Sbjct: 198 CQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAIQMMM 257
Query: 510 EFGAKGVCQRIGFC 551
K +C +GFC
Sbjct: 258 HMQPKEICALVGFC 271
>AL731541-2|CAI40837.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 97.1 bits (231), Expect = 6e-20
Identities = 51/168 (30%), Positives = 80/168 (47%), Gaps = 5/168 (2%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSAECDQFVEKYADLVISLLAQ 242
C +CEF++KE+ I + + EI A +C +PKS+S EC + V+ Y ++S+L +
Sbjct: 315 CEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLE 374
Query: 243 ELDPSEVCEELKLCK----PESXXXXXXXXXXXXCAVCETVVMAVKKVLKNEKLDRNIVH 410
E+ P VC L LC P C VC+ +V + + L+ + I+
Sbjct: 375 EVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILA 434
Query: 411 IIEKSCGLLPAKYNTRCYAMLEVYGESIIH-LIEEFGAKGVCQRIGFC 551
+EK C LP Y +C + Y +I L+E VC +IG C
Sbjct: 435 ALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 482
Score = 55.2 bits (127), Expect = 2e-07
Identities = 27/93 (29%), Positives = 47/93 (50%)
Frame = +3
Query: 6 LPDATVNGRRVSHKSQSNVCVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSA 185
LP TV+ V+ C +C+ ++ +D ++ EI A+ C +P
Sbjct: 393 LPALTVH---VTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQK 449
Query: 186 ECDQFVEKYADLVISLLAQELDPSEVCEELKLC 284
+CDQFV +Y ++I +L + +DPS VC ++ C
Sbjct: 450 QCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 482
Score = 53.6 bits (123), Expect = 7e-07
Identities = 24/77 (31%), Positives = 43/77 (55%), Gaps = 2/77 (2%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPK-SVSAECDQFVEKYADLVISLLA 239
C +C+ V+ D +KD ++EI + C +PK ++SA C + V+ Y +++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 240 QELD-PSEVCEELKLCK 287
E+ P EVC L LC+
Sbjct: 123 GEMSRPGEVCSALNLCE 139
Score = 39.5 bits (88), Expect = 0.013
Identities = 23/91 (25%), Positives = 43/91 (47%), Gaps = 3/91 (3%)
Frame = +3
Query: 333 CAVCETVVMAVKKVLKNEKLDRNIVHIIEKSCGLLP-AKYNTRCYAMLEVYGESIIHLIE 509
C +C+ VV A +LK+ + I+ +EK+C LP + C +++ Y I+ +I+
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 510 -EFGAKG-VCQRIGFCGRTETAYVRMYREKR 596
E G VC + C + + +K+
Sbjct: 123 GEMSRPGEVCSALNLCESLQKHLAELNHQKQ 153
Score = 30.3 bits (65), Expect = 7.7
Identities = 16/74 (21%), Positives = 31/74 (41%), Gaps = 1/74 (1%)
Frame = +3
Query: 333 CAVCETVVMAVKKVLK-NEKLDRNIVHIIEKSCGLLPAKYNTRCYAMLEVYGESIIHLIE 509
C C +V ++ ++ N + +V +++ C L C + Y E I ++
Sbjct: 198 CQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAIQMMM 257
Query: 510 EFGAKGVCQRIGFC 551
K +C +GFC
Sbjct: 258 HMQPKEICALVGFC 271
>AL731541-1|CAI40836.1| 559|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 559
Score = 97.1 bits (231), Expect = 6e-20
Identities = 51/168 (30%), Positives = 80/168 (47%), Gaps = 5/168 (2%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSAECDQFVEKYADLVISLLAQ 242
C +CEF++KE+ I + + EI A +C +PKS+S EC + V+ Y ++S+L +
Sbjct: 315 CEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLE 374
Query: 243 ELDPSEVCEELKLCK----PESXXXXXXXXXXXXCAVCETVVMAVKKVLKNEKLDRNIVH 410
E+ P VC L LC P C VC+ +V + + L+ + I+
Sbjct: 375 EVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILA 434
Query: 411 IIEKSCGLLPAKYNTRCYAMLEVYGESIIH-LIEEFGAKGVCQRIGFC 551
+EK C LP Y +C + Y +I L+E VC +IG C
Sbjct: 435 ALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 482
Score = 55.2 bits (127), Expect = 2e-07
Identities = 27/93 (29%), Positives = 47/93 (50%)
Frame = +3
Query: 6 LPDATVNGRRVSHKSQSNVCVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSA 185
LP TV+ V+ C +C+ ++ +D ++ EI A+ C +P
Sbjct: 393 LPALTVH---VTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQK 449
Query: 186 ECDQFVEKYADLVISLLAQELDPSEVCEELKLC 284
+CDQFV +Y ++I +L + +DPS VC ++ C
Sbjct: 450 QCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 482
Score = 53.6 bits (123), Expect = 7e-07
Identities = 24/77 (31%), Positives = 43/77 (55%), Gaps = 2/77 (2%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPK-SVSAECDQFVEKYADLVISLLA 239
C +C+ V+ D +KD ++EI + C +PK ++SA C + V+ Y +++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 240 QELD-PSEVCEELKLCK 287
E+ P EVC L LC+
Sbjct: 123 GEMSRPGEVCSALNLCE 139
Score = 39.5 bits (88), Expect = 0.013
Identities = 23/91 (25%), Positives = 43/91 (47%), Gaps = 3/91 (3%)
Frame = +3
Query: 333 CAVCETVVMAVKKVLKNEKLDRNIVHIIEKSCGLLP-AKYNTRCYAMLEVYGESIIHLIE 509
C +C+ VV A +LK+ + I+ +EK+C LP + C +++ Y I+ +I+
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 510 -EFGAKG-VCQRIGFCGRTETAYVRMYREKR 596
E G VC + C + + +K+
Sbjct: 123 GEMSRPGEVCSALNLCESLQKHLAELNHQKQ 153
Score = 30.3 bits (65), Expect = 7.7
Identities = 16/74 (21%), Positives = 31/74 (41%), Gaps = 1/74 (1%)
Frame = +3
Query: 333 CAVCETVVMAVKKVLK-NEKLDRNIVHIIEKSCGLLPAKYNTRCYAMLEVYGESIIHLIE 509
C C +V ++ ++ N + +V +++ C L C + Y E I ++
Sbjct: 198 CQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAIQMMM 257
Query: 510 EFGAKGVCQRIGFC 551
K +C +GFC
Sbjct: 258 HMQPKEICALVGFC 271
>AK223290-1|BAD97010.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) v protein.
Length = 524
Score = 97.1 bits (231), Expect = 6e-20
Identities = 51/168 (30%), Positives = 80/168 (47%), Gaps = 5/168 (2%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSAECDQFVEKYADLVISLLAQ 242
C +CEF++KE+ I + + EI A +C +PKS+S EC + V+ Y ++S+L +
Sbjct: 315 CEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLE 374
Query: 243 ELDPSEVCEELKLCK----PESXXXXXXXXXXXXCAVCETVVMAVKKVLKNEKLDRNIVH 410
E+ P VC L LC P C VC+ +V + + L+ + I+
Sbjct: 375 EVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILA 434
Query: 411 IIEKSCGLLPAKYNTRCYAMLEVYGESIIH-LIEEFGAKGVCQRIGFC 551
+EK C LP Y +C + Y +I L+E VC +IG C
Sbjct: 435 ALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 482
Score = 55.2 bits (127), Expect = 2e-07
Identities = 27/93 (29%), Positives = 47/93 (50%)
Frame = +3
Query: 6 LPDATVNGRRVSHKSQSNVCVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSA 185
LP TV+ V+ C +C+ ++ +D ++ EI A+ C +P
Sbjct: 393 LPALTVH---VTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQK 449
Query: 186 ECDQFVEKYADLVISLLAQELDPSEVCEELKLC 284
+CDQFV +Y ++I +L + +DPS VC ++ C
Sbjct: 450 QCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 482
Score = 53.6 bits (123), Expect = 7e-07
Identities = 24/77 (31%), Positives = 43/77 (55%), Gaps = 2/77 (2%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPK-SVSAECDQFVEKYADLVISLLA 239
C +C+ V+ D +KD ++EI + C +PK ++SA C + V+ Y +++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 240 QELD-PSEVCEELKLCK 287
E+ P EVC L LC+
Sbjct: 123 GEMSRPGEVCSALNLCE 139
Score = 39.5 bits (88), Expect = 0.013
Identities = 23/91 (25%), Positives = 43/91 (47%), Gaps = 3/91 (3%)
Frame = +3
Query: 333 CAVCETVVMAVKKVLKNEKLDRNIVHIIEKSCGLLP-AKYNTRCYAMLEVYGESIIHLIE 509
C +C+ VV A +LK+ + I+ +EK+C LP + C +++ Y I+ +I+
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 510 -EFGAKG-VCQRIGFCGRTETAYVRMYREKR 596
E G VC + C + + +K+
Sbjct: 123 GEMSRPGEVCSALNLCESLQKHLAELNHQKQ 153
Score = 30.3 bits (65), Expect = 7.7
Identities = 16/74 (21%), Positives = 31/74 (41%), Gaps = 1/74 (1%)
Frame = +3
Query: 333 CAVCETVVMAVKKVLK-NEKLDRNIVHIIEKSCGLLPAKYNTRCYAMLEVYGESIIHLIE 509
C C +V ++ ++ N + +V +++ C L C + Y E I ++
Sbjct: 198 CQDCIRMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAIQMMM 257
Query: 510 EFGAKGVCQRIGFC 551
K +C +GFC
Sbjct: 258 HMQPKEICALVGFC 271
>AB209776-1|BAD93013.1| 530|Homo sapiens prosaposin variant
protein.
Length = 530
Score = 97.1 bits (231), Expect = 6e-20
Identities = 51/168 (30%), Positives = 80/168 (47%), Gaps = 5/168 (2%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSAECDQFVEKYADLVISLLAQ 242
C +CEF++KE+ I + + EI A +C +PKS+S EC + V+ Y ++S+L +
Sbjct: 321 CEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLE 380
Query: 243 ELDPSEVCEELKLCK----PESXXXXXXXXXXXXCAVCETVVMAVKKVLKNEKLDRNIVH 410
E+ P VC L LC P C VC+ +V + + L+ + I+
Sbjct: 381 EVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILA 440
Query: 411 IIEKSCGLLPAKYNTRCYAMLEVYGESIIH-LIEEFGAKGVCQRIGFC 551
+EK C LP Y +C + Y +I L+E VC +IG C
Sbjct: 441 ALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 488
Score = 55.2 bits (127), Expect = 2e-07
Identities = 27/93 (29%), Positives = 47/93 (50%)
Frame = +3
Query: 6 LPDATVNGRRVSHKSQSNVCVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSA 185
LP TV+ V+ C +C+ ++ +D ++ EI A+ C +P
Sbjct: 399 LPALTVH---VTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQK 455
Query: 186 ECDQFVEKYADLVISLLAQELDPSEVCEELKLC 284
+CDQFV +Y ++I +L + +DPS VC ++ C
Sbjct: 456 QCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 488
Score = 53.6 bits (123), Expect = 7e-07
Identities = 24/77 (31%), Positives = 43/77 (55%), Gaps = 2/77 (2%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPK-SVSAECDQFVEKYADLVISLLA 239
C +C+ V+ D +KD ++EI + C +PK ++SA C + V+ Y +++ ++
Sbjct: 66 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 125
Query: 240 QELD-PSEVCEELKLCK 287
E+ P EVC L LC+
Sbjct: 126 GEMSRPGEVCSALNLCE 142
Score = 39.5 bits (88), Expect = 0.013
Identities = 23/91 (25%), Positives = 43/91 (47%), Gaps = 3/91 (3%)
Frame = +3
Query: 333 CAVCETVVMAVKKVLKNEKLDRNIVHIIEKSCGLLP-AKYNTRCYAMLEVYGESIIHLIE 509
C +C+ VV A +LK+ + I+ +EK+C LP + C +++ Y I+ +I+
Sbjct: 66 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 125
Query: 510 -EFGAKG-VCQRIGFCGRTETAYVRMYREKR 596
E G VC + C + + +K+
Sbjct: 126 GEMSRPGEVCSALNLCESLQKHLAELNHQKQ 156
>CR456746-1|CAG33027.1| 524|Homo sapiens PSAP protein.
Length = 524
Score = 95.1 bits (226), Expect = 2e-19
Identities = 51/168 (30%), Positives = 79/168 (47%), Gaps = 5/168 (2%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSAECDQFVEKYADLVISLLAQ 242
C +CEF++KE+ I + + EI A +C +PKS+S EC + V+ Y + S+L +
Sbjct: 315 CEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSIPSILLE 374
Query: 243 ELDPSEVCEELKLCK----PESXXXXXXXXXXXXCAVCETVVMAVKKVLKNEKLDRNIVH 410
E+ P VC L LC P C VC+ +V + + L+ + I+
Sbjct: 375 EVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILA 434
Query: 411 IIEKSCGLLPAKYNTRCYAMLEVYGESIIH-LIEEFGAKGVCQRIGFC 551
+EK C LP Y +C + Y +I L+E VC +IG C
Sbjct: 435 ALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 482
Score = 55.2 bits (127), Expect = 2e-07
Identities = 27/93 (29%), Positives = 47/93 (50%)
Frame = +3
Query: 6 LPDATVNGRRVSHKSQSNVCVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSA 185
LP TV+ V+ C +C+ ++ +D ++ EI A+ C +P
Sbjct: 393 LPALTVH---VTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQK 449
Query: 186 ECDQFVEKYADLVISLLAQELDPSEVCEELKLC 284
+CDQFV +Y ++I +L + +DPS VC ++ C
Sbjct: 450 QCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 482
Score = 53.6 bits (123), Expect = 7e-07
Identities = 24/77 (31%), Positives = 43/77 (55%), Gaps = 2/77 (2%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPK-SVSAECDQFVEKYADLVISLLA 239
C +C+ V+ D +KD ++EI + C +PK ++SA C + V+ Y +++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 240 QELD-PSEVCEELKLCK 287
E+ P EVC L LC+
Sbjct: 123 GEMSRPGEVCSALNLCE 139
Score = 39.5 bits (88), Expect = 0.013
Identities = 23/91 (25%), Positives = 43/91 (47%), Gaps = 3/91 (3%)
Frame = +3
Query: 333 CAVCETVVMAVKKVLKNEKLDRNIVHIIEKSCGLLP-AKYNTRCYAMLEVYGESIIHLIE 509
C +C+ VV A +LK+ + I+ +EK+C LP + C +++ Y I+ +I+
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 510 -EFGAKG-VCQRIGFCGRTETAYVRMYREKR 596
E G VC + C + + +K+
Sbjct: 123 GEMSRPGEVCSALNLCESLQKHLAELNHQKQ 153
Score = 30.3 bits (65), Expect = 7.7
Identities = 16/74 (21%), Positives = 31/74 (41%), Gaps = 1/74 (1%)
Frame = +3
Query: 333 CAVCETVVMAVKKVLK-NEKLDRNIVHIIEKSCGLLPAKYNTRCYAMLEVYGESIIHLIE 509
C C +V ++ ++ N + +V +++ C L C + Y E I ++
Sbjct: 198 CQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAIQMMM 257
Query: 510 EFGAKGVCQRIGFC 551
K +C +GFC
Sbjct: 258 HMQPKEICALVGFC 271
>DQ991252-1|ABJ55983.1| 521|Homo sapiens prosaposin-like protein 1
protein.
Length = 521
Score = 60.1 bits (139), Expect = 8e-09
Identities = 37/177 (20%), Positives = 79/177 (44%), Gaps = 14/177 (7%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSAECDQFVEKYADLVISLLAQ 242
C +C V++++D + ++ I A+ +C MP S++ EC V+ Y+ ++ L+A
Sbjct: 294 CEVCMNVVQKLDHWLMSNSSELMITHALERVCSVMPASITKECIILVDTYSPSLVQLVA- 352
Query: 243 ELDPSEVCEELKLCKPESXXXXXXXXXX-------------XXCAVCETVVMAVKKVLKN 383
++ P +VC+ ++LC C C+ ++ L++
Sbjct: 353 KITPEKVCKFIRLCGNRRRARAVHDAYAIVPSPEWDAENQGSFCNGCKRLLTVSSHNLES 412
Query: 384 EKLDRNIVHIIEKSCGLLPAKYNTRCYAMLEVYGESIIHLIEE-FGAKGVCQRIGFC 551
+ R+I+ + C +LP Y +C + Y +I +++ VC+++G C
Sbjct: 413 KSTKRDILVAFKGGCSILPLPYMIQCKHFVTQYEPVLIESLKDMMDPVAVCKKVGAC 469
Score = 52.8 bits (121), Expect = 1e-06
Identities = 22/79 (27%), Positives = 38/79 (48%)
Frame = +3
Query: 333 CAVCETVVMAVKKVLKNEKLDRNIVHIIEKSCGLLPAKYNTRCYAMLEVYGESIIHLIEE 512
C VC VV + L + + I H +E+ C ++PA C +++ Y S++ L+ +
Sbjct: 294 CEVCMNVVQKLDHWLMSNSSELMITHALERVCSVMPASITKECIILVDTYSPSLVQLVAK 353
Query: 513 FGAKGVCQRIGFCGRTETA 569
+ VC+ I CG A
Sbjct: 354 ITPEKVCKFIRLCGNRRRA 372
Score = 43.6 bits (98), Expect = 8e-04
Identities = 21/80 (26%), Positives = 38/80 (47%)
Frame = +3
Query: 45 KSQSNVCVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSAECDQFVEKYADLV 224
++Q + C C+ +L ++ K +I A G C +P +C FV +Y ++
Sbjct: 390 ENQGSFCNGCKRLLTVSSHNLESKSTKRDILVAFKGGCSILPLPYMIQCKHFVTQYEPVL 449
Query: 225 ISLLAQELDPSEVCEELKLC 284
I L +DP VC+++ C
Sbjct: 450 IESLKDMMDPVAVCKKVGAC 469
Score = 39.1 bits (87), Expect = 0.017
Identities = 21/84 (25%), Positives = 43/84 (51%), Gaps = 3/84 (3%)
Frame = +3
Query: 48 SQSNVCVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMP-KSVSAECDQFVEKYADLV 224
++S C +C+ + + + + +I V C+ +P + SA C V+ ++ +
Sbjct: 59 AKSLPCDVCQDIAAAAGNGLNPDATESDILALVMKTCEWLPSQESSAGCKWMVDAHSSAI 118
Query: 225 ISLL--AQELDPSEVCEELKLCKP 290
+S+L A + P++VC L LC+P
Sbjct: 119 LSMLRGAPDSAPAQVCTALSLCEP 142
Score = 32.7 bits (71), Expect = 1.4
Identities = 16/77 (20%), Positives = 38/77 (49%), Gaps = 4/77 (5%)
Frame = +3
Query: 333 CAVCETVVMAVKKVLKNEKLDRNIVHIIEKSCGLLPAKYNTR-CYAMLEVYGESIIHLIE 509
C VC+ + A L + + +I+ ++ K+C LP++ ++ C M++ + +I+ ++
Sbjct: 64 CDVCQDIAAAAGNGLNPDATESDILALVMKTCEWLPSQESSAGCKWMVDAHSSAILSMLR 123
Query: 510 ---EFGAKGVCQRIGFC 551
+ VC + C
Sbjct: 124 GAPDSAPAQVCTALSLC 140
>BC068579-1|AAH68579.1| 543|Homo sapiens PSAPL1 protein protein.
Length = 543
Score = 60.1 bits (139), Expect = 8e-09
Identities = 37/177 (20%), Positives = 79/177 (44%), Gaps = 14/177 (7%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSAECDQFVEKYADLVISLLAQ 242
C +C V++++D + ++ I A+ +C MP S++ EC V+ Y+ ++ L+A
Sbjct: 316 CEVCMNVVQKLDHWLMSNSSELMITHALERVCSVMPASITKECIILVDTYSPSLVQLVA- 374
Query: 243 ELDPSEVCEELKLCKPESXXXXXXXXXX-------------XXCAVCETVVMAVKKVLKN 383
++ P +VC+ ++LC C C+ ++ L++
Sbjct: 375 KITPEKVCKFIRLCGNRRRARAVHDAYAIVPSPEWDAENQGSFCNGCKRLLTVSSHNLES 434
Query: 384 EKLDRNIVHIIEKSCGLLPAKYNTRCYAMLEVYGESIIHLIEE-FGAKGVCQRIGFC 551
+ R+I+ + C +LP Y +C + Y +I +++ VC+++G C
Sbjct: 435 KSTKRDILVAFKGGCSILPLPYMIQCKHFVTQYEPVLIESLKDMMDPVAVCKKVGAC 491
Score = 52.8 bits (121), Expect = 1e-06
Identities = 22/79 (27%), Positives = 38/79 (48%)
Frame = +3
Query: 333 CAVCETVVMAVKKVLKNEKLDRNIVHIIEKSCGLLPAKYNTRCYAMLEVYGESIIHLIEE 512
C VC VV + L + + I H +E+ C ++PA C +++ Y S++ L+ +
Sbjct: 316 CEVCMNVVQKLDHWLMSNSSELMITHALERVCSVMPASITKECIILVDTYSPSLVQLVAK 375
Query: 513 FGAKGVCQRIGFCGRTETA 569
+ VC+ I CG A
Sbjct: 376 ITPEKVCKFIRLCGNRRRA 394
Score = 43.6 bits (98), Expect = 8e-04
Identities = 21/80 (26%), Positives = 38/80 (47%)
Frame = +3
Query: 45 KSQSNVCVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSAECDQFVEKYADLV 224
++Q + C C+ +L ++ K +I A G C +P +C FV +Y ++
Sbjct: 412 ENQGSFCNGCKRLLTVSSHNLESKSTKRDILVAFKGGCSILPLPYMIQCKHFVTQYEPVL 471
Query: 225 ISLLAQELDPSEVCEELKLC 284
I L +DP VC+++ C
Sbjct: 472 IESLKDMMDPVAVCKKVGAC 491
Score = 39.1 bits (87), Expect = 0.017
Identities = 21/84 (25%), Positives = 43/84 (51%), Gaps = 3/84 (3%)
Frame = +3
Query: 48 SQSNVCVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMP-KSVSAECDQFVEKYADLV 224
++S C +C+ + + + + +I V C+ +P + SA C V+ ++ +
Sbjct: 81 AKSLPCDVCQDIAAAAGNGLNPDATESDILALVMKTCEWLPSQESSAGCKWMVDAHSSAI 140
Query: 225 ISLL--AQELDPSEVCEELKLCKP 290
+S+L A + P++VC L LC+P
Sbjct: 141 LSMLRGAPDSAPAQVCTALSLCEP 164
Score = 32.7 bits (71), Expect = 1.4
Identities = 16/77 (20%), Positives = 38/77 (49%), Gaps = 4/77 (5%)
Frame = +3
Query: 333 CAVCETVVMAVKKVLKNEKLDRNIVHIIEKSCGLLPAKYNTR-CYAMLEVYGESIIHLIE 509
C VC+ + A L + + +I+ ++ K+C LP++ ++ C M++ + +I+ ++
Sbjct: 86 CDVCQDIAAAAGNGLNPDATESDILALVMKTCEWLPSQESSAGCKWMVDAHSSAILSMLR 145
Query: 510 ---EFGAKGVCQRIGFC 551
+ VC + C
Sbjct: 146 GAPDSAPAQVCTALSLC 162
>AK097698-1|BAC05143.1| 241|Homo sapiens protein ( Homo sapiens
cDNA FLJ40379 fis, clone TESTI2035262, weakly similar to
PROACTIVATOR POLYPEPTIDE PRECURSOR. ).
Length = 241
Score = 60.1 bits (139), Expect = 8e-09
Identities = 37/177 (20%), Positives = 79/177 (44%), Gaps = 14/177 (7%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSAECDQFVEKYADLVISLLAQ 242
C +C V++++D + ++ I A+ +C MP S++ EC V+ Y+ ++ L+A
Sbjct: 26 CEVCMNVVQKLDHWLMSNSSELMITHALERVCSVMPASITKECIILVDTYSPSLVQLVA- 84
Query: 243 ELDPSEVCEELKLCKPESXXXXXXXXXX-------------XXCAVCETVVMAVKKVLKN 383
++ P +VC+ ++LC C C+ ++ L++
Sbjct: 85 KITPEKVCKFIRLCGNRRRARAVHDAYAIVPSPEWDAENQGSFCNGCKRLLTVSSHNLES 144
Query: 384 EKLDRNIVHIIEKSCGLLPAKYNTRCYAMLEVYGESIIHLIEE-FGAKGVCQRIGFC 551
+ R+I+ + C +LP Y +C + Y +I +++ VC+++G C
Sbjct: 145 KSTKRDILVAFKGGCSILPLPYMIQCKHFVTQYEPVLIESLKDMMDPVAVCKKVGAC 201
Score = 52.8 bits (121), Expect = 1e-06
Identities = 22/79 (27%), Positives = 38/79 (48%)
Frame = +3
Query: 333 CAVCETVVMAVKKVLKNEKLDRNIVHIIEKSCGLLPAKYNTRCYAMLEVYGESIIHLIEE 512
C VC VV + L + + I H +E+ C ++PA C +++ Y S++ L+ +
Sbjct: 26 CEVCMNVVQKLDHWLMSNSSELMITHALERVCSVMPASITKECIILVDTYSPSLVQLVAK 85
Query: 513 FGAKGVCQRIGFCGRTETA 569
+ VC+ I CG A
Sbjct: 86 ITPEKVCKFIRLCGNRRRA 104
Score = 43.6 bits (98), Expect = 8e-04
Identities = 21/80 (26%), Positives = 38/80 (47%)
Frame = +3
Query: 45 KSQSNVCVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSAECDQFVEKYADLV 224
++Q + C C+ +L ++ K +I A G C +P +C FV +Y ++
Sbjct: 122 ENQGSFCNGCKRLLTVSSHNLESKSTKRDILVAFKGGCSILPLPYMIQCKHFVTQYEPVL 181
Query: 225 ISLLAQELDPSEVCEELKLC 284
I L +DP VC+++ C
Sbjct: 182 IESLKDMMDPVAVCKKVGAC 201
>BC091483-1|AAH91483.1| 240|Homo sapiens PSAP protein protein.
Length = 240
Score = 55.2 bits (127), Expect = 2e-07
Identities = 27/93 (29%), Positives = 47/93 (50%)
Frame = +3
Query: 6 LPDATVNGRRVSHKSQSNVCVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSA 185
LP TV+ V+ C +C+ ++ +D ++ EI A+ C +P
Sbjct: 109 LPALTVH---VTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQK 165
Query: 186 ECDQFVEKYADLVISLLAQELDPSEVCEELKLC 284
+CDQFV +Y ++I +L + +DPS VC ++ C
Sbjct: 166 QCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 198
Score = 51.2 bits (117), Expect = 4e-06
Identities = 40/149 (26%), Positives = 60/149 (40%), Gaps = 5/149 (3%)
Frame = +3
Query: 120 NDDEIKKAVHGICKHMPKSVSAECDQFVEKYADLVISLLAQELDPSEVCEELKLCK---- 287
N +K ICK + V+A D + + I L+ E+ P VC L LC
Sbjct: 54 NKPTVKSLPCDICKDV---VTAAGDMLKDNATEEEI-LVYLEVSPELVCSMLHLCSGTRL 109
Query: 288 PESXXXXXXXXXXXXCAVCETVVMAVKKVLKNEKLDRNIVHIIEKSCGLLPAKYNTRCYA 467
P C VC+ +V + + L+ + I+ +EK C LP Y +C
Sbjct: 110 PALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQ 169
Query: 468 MLEVYGESIIH-LIEEFGAKGVCQRIGFC 551
+ Y +I L+E VC +IG C
Sbjct: 170 FVAEYEPVLIEILVEVMDPSFVCLKIGAC 198
>M24461-1|AAB59541.1| 381|Homo sapiens pulmonary
surfactant-associated protein SP-B protein.
Length = 381
Score = 46.8 bits (106), Expect = 8e-05
Identities = 22/83 (26%), Positives = 42/83 (50%), Gaps = 1/83 (1%)
Frame = +3
Query: 42 HKSQSNVCVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMP-KSVSAECDQFVEKYAD 218
H ++C CE ++ ++ K+ D ++K + C +P K + +C+Q ++ Y
Sbjct: 62 HVGADDLCQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFP 121
Query: 219 LVISLLAQELDPSEVCEELKLCK 287
LVI ++D + +C L LCK
Sbjct: 122 LVIDYFQNQIDSNGICMHLGLCK 144
Score = 39.5 bits (88), Expect = 0.013
Identities = 19/75 (25%), Positives = 35/75 (46%), Gaps = 2/75 (2%)
Frame = +3
Query: 333 CAVCETVVMAVKKVLKNEKLDRNIVHIIEKSCGLLPAK-YNTRCYAMLEVYGESIIHLIE 509
C CE +V + K+ K + +E+ C +LP K +C +L+ Y +I +
Sbjct: 69 CQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFPLVIDYFQ 128
Query: 510 -EFGAKGVCQRIGFC 551
+ + G+C +G C
Sbjct: 129 NQIDSNGICMHLGLC 143
Score = 33.1 bits (72), Expect = 1.1
Identities = 33/166 (19%), Positives = 64/166 (38%), Gaps = 2/166 (1%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSAECDQFVEKYADLVISLLAQ 242
C LC ++K I I ++ AV +C+ +P C E+Y+ +++ L
Sbjct: 208 CWLCRALIKRIQAMIPK----GALRVAVAQVCRVVPLVAGGICQCLAERYSVILLDTLLG 263
Query: 243 ELDPSEVCEELKLCKPESXXXXXXXXXXXXCAVCET-VVMAVKKVLKNEKLDRNIVHIIE 419
+ P VC + C + E + M+V N ++ I +
Sbjct: 264 RMLPQLVCRLVLRCSMDDSAGPRSPTGEWLPRDSECHLCMSVTTQAGNSS-EQAIPQAML 322
Query: 420 KSCGLLPAKYNTRCYAMLEVYGESIIHLIEE-FGAKGVCQRIGFCG 554
++C + +C +E + ++ L+ + A CQ +G CG
Sbjct: 323 QAC-VGSWLDREKCKQFVEQHTPQLLTLVPRGWDAHTTCQALGVCG 367
>AF400074-1|AAK77913.1| 381|Homo sapiens surfactant,
pulmonary-associated protein B protein.
Length = 381
Score = 46.8 bits (106), Expect = 8e-05
Identities = 22/83 (26%), Positives = 42/83 (50%), Gaps = 1/83 (1%)
Frame = +3
Query: 42 HKSQSNVCVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMP-KSVSAECDQFVEKYAD 218
H ++C CE ++ ++ K+ D ++K + C +P K + +C+Q ++ Y
Sbjct: 62 HVGADDLCQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFP 121
Query: 219 LVISLLAQELDPSEVCEELKLCK 287
LVI ++D + +C L LCK
Sbjct: 122 LVIDYFQNQIDSNGICMHLGLCK 144
Score = 39.5 bits (88), Expect = 0.013
Identities = 19/75 (25%), Positives = 35/75 (46%), Gaps = 2/75 (2%)
Frame = +3
Query: 333 CAVCETVVMAVKKVLKNEKLDRNIVHIIEKSCGLLPAK-YNTRCYAMLEVYGESIIHLIE 509
C CE +V + K+ K + +E+ C +LP K +C +L+ Y +I +
Sbjct: 69 CQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFPLVIDYFQ 128
Query: 510 -EFGAKGVCQRIGFC 551
+ + G+C +G C
Sbjct: 129 NQIDSNGICMHLGLC 143
Score = 31.9 bits (69), Expect = 2.5
Identities = 33/166 (19%), Positives = 63/166 (37%), Gaps = 2/166 (1%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSAECDQFVEKYADLVISLLAQ 242
C LC ++K I I + AV +C+ +P C E+Y+ +++ L
Sbjct: 208 CWLCRALIKRIQAMIPK----GALAVAVAQVCRVVPLVAGGICQCLAERYSVILLDTLLG 263
Query: 243 ELDPSEVCEELKLCKPESXXXXXXXXXXXXCAVCET-VVMAVKKVLKNEKLDRNIVHIIE 419
+ P VC + C + E + M+V N ++ I +
Sbjct: 264 RMLPQLVCRLVLRCSMDDSAGPRSPTGEWLPRDSECHLCMSVTTQAGNSS-EQAIPQAML 322
Query: 420 KSCGLLPAKYNTRCYAMLEVYGESIIHLIEE-FGAKGVCQRIGFCG 554
++C + +C +E + ++ L+ + A CQ +G CG
Sbjct: 323 QAC-VGSWLDREKCKQFVEQHTPQLLTLVPRGWDAHTTCQALGVCG 367
>DQ317589-1|ABC59511.1| 147|Homo sapiens truncated surfactant
pulmonary-associated protein B protein.
Length = 147
Score = 46.0 bits (104), Expect = 1e-04
Identities = 21/83 (25%), Positives = 42/83 (50%), Gaps = 1/83 (1%)
Frame = +3
Query: 42 HKSQSNVCVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMP-KSVSAECDQFVEKYAD 218
H ++C CE ++ ++ K+ D +++ + C +P K + +C+Q ++ Y
Sbjct: 58 HVGADDLCQECEDIVHILNKMAKEAIFQDTMREFLEQECNVLPLKLLMPQCNQVLDDYFP 117
Query: 219 LVISLLAQELDPSEVCEELKLCK 287
LVI ++D + +C L LCK
Sbjct: 118 LVIDYFQNQIDSNSICMHLGLCK 140
Score = 37.5 bits (83), Expect = 0.051
Identities = 18/75 (24%), Positives = 34/75 (45%), Gaps = 2/75 (2%)
Frame = +3
Query: 333 CAVCETVVMAVKKVLKNEKLDRNIVHIIEKSCGLLPAK-YNTRCYAMLEVYGESIIHLIE 509
C CE +V + K+ K + +E+ C +LP K +C +L+ Y +I +
Sbjct: 65 CQECEDIVHILNKMAKEAIFQDTMREFLEQECNVLPLKLLMPQCNQVLDDYFPLVIDYFQ 124
Query: 510 -EFGAKGVCQRIGFC 551
+ + +C +G C
Sbjct: 125 NQIDSNSICMHLGLC 139
>J02761-1|AAA60212.1| 381|Homo sapiens pulmonary
surfactant-associated protein SP-B protein.
Length = 381
Score = 45.6 bits (103), Expect = 2e-04
Identities = 22/83 (26%), Positives = 41/83 (49%), Gaps = 1/83 (1%)
Frame = +3
Query: 42 HKSQSNVCVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMP-KSVSAECDQFVEKYAD 218
H ++C CE ++ ++ K+ D ++K + C +P K + +C+Q ++ Y
Sbjct: 62 HVGADDLCQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFP 121
Query: 219 LVISLLAQELDPSEVCEELKLCK 287
LVI + D + +C L LCK
Sbjct: 122 LVIDYFQNQTDSNGICMHLGLCK 144
Score = 38.7 bits (86), Expect = 0.022
Identities = 19/75 (25%), Positives = 35/75 (46%), Gaps = 2/75 (2%)
Frame = +3
Query: 333 CAVCETVVMAVKKVLKNEKLDRNIVHIIEKSCGLLPAK-YNTRCYAMLEVYGESIIHLIE 509
C CE +V + K+ K + +E+ C +LP K +C +L+ Y +I +
Sbjct: 69 CQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFPLVIDYFQ 128
Query: 510 -EFGAKGVCQRIGFC 551
+ + G+C +G C
Sbjct: 129 NQTDSNGICMHLGLC 143
Score = 31.9 bits (69), Expect = 2.5
Identities = 33/166 (19%), Positives = 63/166 (37%), Gaps = 2/166 (1%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSAECDQFVEKYADLVISLLAQ 242
C LC ++K I I + AV +C+ +P C E+Y+ +++ L
Sbjct: 208 CWLCRALIKRIQAMIPK----GALAVAVAQVCRVVPLVAGGICQCLAERYSVILLDTLLG 263
Query: 243 ELDPSEVCEELKLCKPESXXXXXXXXXXXXCAVCET-VVMAVKKVLKNEKLDRNIVHIIE 419
+ P VC + C + E + M+V N ++ I +
Sbjct: 264 RMLPQLVCRLVLRCSMDDSAGPRSPTGEWLPRDSECHLCMSVTTQAGNSS-EQAIPQAML 322
Query: 420 KSCGLLPAKYNTRCYAMLEVYGESIIHLIEE-FGAKGVCQRIGFCG 554
++C + +C +E + ++ L+ + A CQ +G CG
Sbjct: 323 QAC-VGSWLDREKCKQFVEQHTPQLLTLVPRGWDAHTTCQALGVCG 367
>BC032785-1|AAH32785.1| 381|Homo sapiens surfactant,
pulmonary-associated protein B protein.
Length = 381
Score = 45.6 bits (103), Expect = 2e-04
Identities = 22/83 (26%), Positives = 41/83 (49%), Gaps = 1/83 (1%)
Frame = +3
Query: 42 HKSQSNVCVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMP-KSVSAECDQFVEKYAD 218
H ++C CE ++ ++ K+ D ++K + C +P K + +C+Q ++ Y
Sbjct: 62 HVGADDLCQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFP 121
Query: 219 LVISLLAQELDPSEVCEELKLCK 287
LVI + D + +C L LCK
Sbjct: 122 LVIDYFQNQTDSNGICMHLGLCK 144
Score = 38.7 bits (86), Expect = 0.022
Identities = 19/75 (25%), Positives = 35/75 (46%), Gaps = 2/75 (2%)
Frame = +3
Query: 333 CAVCETVVMAVKKVLKNEKLDRNIVHIIEKSCGLLPAK-YNTRCYAMLEVYGESIIHLIE 509
C CE +V + K+ K + +E+ C +LP K +C +L+ Y +I +
Sbjct: 69 CQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFPLVIDYFQ 128
Query: 510 -EFGAKGVCQRIGFC 551
+ + G+C +G C
Sbjct: 129 NQTDSNGICMHLGLC 143
Score = 31.9 bits (69), Expect = 2.5
Identities = 33/166 (19%), Positives = 63/166 (37%), Gaps = 2/166 (1%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSAECDQFVEKYADLVISLLAQ 242
C LC ++K I I + AV +C+ +P C E+Y+ +++ L
Sbjct: 208 CWLCRALIKRIQAMIPK----GALAVAVAQVCRVVPLVAGGICQCLAERYSVILLDTLLG 263
Query: 243 ELDPSEVCEELKLCKPESXXXXXXXXXXXXCAVCET-VVMAVKKVLKNEKLDRNIVHIIE 419
+ P VC + C + E + M+V N ++ I +
Sbjct: 264 RMLPQLVCRLVLRCSMDDSAGPRSPTGEWLPRDSECHLCMSVTTQAGNSS-EQAIPQAML 322
Query: 420 KSCGLLPAKYNTRCYAMLEVYGESIIHLIEE-FGAKGVCQRIGFCG 554
++C + +C +E + ++ L+ + A CQ +G CG
Sbjct: 323 QAC-VGSWLDREKCKQFVEQHTPQLLTLVPRGWDAHTTCQALGVCG 367
>M62840-1|AAA35506.1| 575|Homo sapiens acyloxyacyl hydrolase
protein.
Length = 575
Score = 43.6 bits (98), Expect = 8e-04
Identities = 21/82 (25%), Positives = 43/82 (52%), Gaps = 2/82 (2%)
Frame = +3
Query: 48 SQSNVCVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSV--SAECDQFVEKYADL 221
S + CV C V+ I+ Q+ HN ++ ++ +C ++P+ + C ++K+
Sbjct: 36 SNGHTCVGCVLVVSVIE-QLAQVHNST-VQASMERLCSYLPEKLFLKTTCYLVIDKFGSD 93
Query: 222 VISLLAQELDPSEVCEELKLCK 287
+I LL+ +++ VC L+ CK
Sbjct: 94 IIKLLSADMNADVVCHTLEFCK 115
>BC025698-1|AAH25698.1| 575|Homo sapiens acyloxyacyl hydrolase
(neutrophil) protein.
Length = 575
Score = 43.6 bits (98), Expect = 8e-04
Identities = 21/82 (25%), Positives = 43/82 (52%), Gaps = 2/82 (2%)
Frame = +3
Query: 48 SQSNVCVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSV--SAECDQFVEKYADL 221
S + CV C V+ I+ Q+ HN ++ ++ +C ++P+ + C ++K+
Sbjct: 36 SNGHTCVGCVLVVSVIE-QLAQVHNST-VQASMERLCSYLPEKLFLKTTCYLVIDKFGSD 93
Query: 222 VISLLAQELDPSEVCEELKLCK 287
+I LL+ +++ VC L+ CK
Sbjct: 94 IIKLLSADMNADVVCHTLEFCK 115
>AK223476-1|BAD97196.1| 575|Homo sapiens acyloxyacyl hydrolase
precursor variant protein.
Length = 575
Score = 43.6 bits (98), Expect = 8e-04
Identities = 21/82 (25%), Positives = 43/82 (52%), Gaps = 2/82 (2%)
Frame = +3
Query: 48 SQSNVCVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSV--SAECDQFVEKYADL 221
S + CV C V+ I+ Q+ HN ++ ++ +C ++P+ + C ++K+
Sbjct: 36 SNGHTCVGCVLVVSVIE-QLAQVHNST-VQASMERLCSYLPEKLFLKTTCYLVIDKFGSD 93
Query: 222 VISLLAQELDPSEVCEELKLCK 287
+I LL+ +++ VC L+ CK
Sbjct: 94 IIKLLSADMNADVVCHTLEFCK 115
>X57107-1|CAA40391.1| 67|Homo sapiens cerebroside sulfate
activator protein.
Length = 67
Score = 41.1 bits (92), Expect = 0.004
Identities = 17/63 (26%), Positives = 35/63 (55%), Gaps = 1/63 (1%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPK-SVSAECDQFVEKYADLVISLLA 239
C +C+ V+ D +KD ++EI + C +PK ++SA C + V+ Y +++ ++
Sbjct: 5 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 64
Query: 240 QEL 248
E+
Sbjct: 65 GEM 67
Score = 34.7 bits (76), Expect = 0.36
Identities = 17/60 (28%), Positives = 32/60 (53%), Gaps = 1/60 (1%)
Frame = +3
Query: 333 CAVCETVVMAVKKVLKNEKLDRNIVHIIEKSCGLLP-AKYNTRCYAMLEVYGESIIHLIE 509
C +C+ VV A +LK+ + I+ +EK+C LP + C +++ Y I+ +I+
Sbjct: 5 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 64
>X05044-2|CAA28715.1| 129|Homo sapiens protein ( Human mRNA
(AH2-519) for gene 519 from functional T-cell line. ).
Length = 129
Score = 34.3 bits (75), Expect = 0.47
Identities = 17/75 (22%), Positives = 33/75 (44%)
Frame = +3
Query: 72 CEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSAECDQFVEKYADLVISLLAQELD 251
C +++++ + DK + A +C+ C F+ +Y VI L
Sbjct: 53 CLTIVQKLKKMV-DKPTQRSVSNAATRVCRTGRSRWRDVCRNFMRRYQSRVIQGLVAGET 111
Query: 252 PSEVCEELKLCKPES 296
++CE+L+LC P +
Sbjct: 112 AQQICEDLRLCIPST 126
>M85276-1|AAA59935.1| 145|Homo sapiens NKG5 protein protein.
Length = 145
Score = 34.3 bits (75), Expect = 0.47
Identities = 17/75 (22%), Positives = 33/75 (44%)
Frame = +3
Query: 72 CEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSAECDQFVEKYADLVISLLAQELD 251
C +++++ + DK + A +C+ C F+ +Y VI L
Sbjct: 69 CLTIVQKLKKMV-DKPTQRSVSNAATRVCRTGRSRWRDVCRNFMRRYQSRVIQGLVAGET 127
Query: 252 PSEVCEELKLCKPES 296
++CE+L+LC P +
Sbjct: 128 AQQICEDLRLCIPST 142
>M16764-1|AAA88099.1| 286|Homo sapiens pulmonary
surfactant-associated proteolipid protein protein.
Length = 286
Score = 34.3 bits (75), Expect = 0.47
Identities = 33/166 (19%), Positives = 65/166 (39%), Gaps = 2/166 (1%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSAECDQFVEKYADLVISLLAQ 242
C LC ++K I I ++ AV +C+ +P C E+Y+ +++ L
Sbjct: 113 CWLCRALIKRIQAMIPK----GALRVAVAQVCRVVPLVAGGICQCLAERYSVILLDTLLG 168
Query: 243 ELDPSEVCEELKLCKPESXXXXXXXXXXXXCAVCET-VVMAVKKVLKNEKLDRNIVHIIE 419
+ P VC + C + E + M+V N ++ I+ +
Sbjct: 169 RMLPQLVCRLVLRCSMDDSAGPRSPTGEWLPRDSECHLCMSVTTQAGNSS-EQAILQAML 227
Query: 420 KSCGLLPAKYNTRCYAMLEVYGESIIHLIEE-FGAKGVCQRIGFCG 554
++C + +C +E + ++ L+ + A CQ +G CG
Sbjct: 228 QAC-VGSWLDREKCKQFVEQHTPQLLTLVPRGWDAHTTCQALGVCG 272
Score = 33.5 bits (73), Expect = 0.82
Identities = 15/45 (33%), Positives = 24/45 (53%), Gaps = 1/45 (2%)
Frame = +3
Query: 156 CKHMP-KSVSAECDQFVEKYADLVISLLAQELDPSEVCEELKLCK 287
C +P K + +C+Q ++ Y LVI + D + +C L LCK
Sbjct: 5 CNVLPLKLLMPQCNQVLDDYFPLVIDYFQNQTDSNGICMHLGLCK 49
>DQ149929-1|ABA06536.1| 916|Homo sapiens serine protease inhibitor
Kazal-type 5 short isoform protein.
Length = 916
Score = 33.1 bits (72), Expect = 1.1
Identities = 18/70 (25%), Positives = 35/70 (50%)
Frame = +3
Query: 45 KSQSNVCVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSAECDQFVEKYADLV 224
K+ N C +C+ V ++ +++ K K +D+ A HG + EC ++ E+ +
Sbjct: 659 KTHGNKCAMCKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYQEQMKNGR 718
Query: 225 ISLLAQELDP 254
+S +E DP
Sbjct: 719 LS-CTRESDP 727
>DQ149928-1|ABA06535.1| 1094|Homo sapiens serine protease inhibitor
Kazal-type 5 long isoform protein.
Length = 1094
Score = 33.1 bits (72), Expect = 1.1
Identities = 18/70 (25%), Positives = 35/70 (50%)
Frame = +3
Query: 45 KSQSNVCVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSAECDQFVEKYADLV 224
K+ N C +C+ V ++ +++ K K +D+ A HG + EC ++ E+ +
Sbjct: 659 KTHGNKCAMCKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYQEQMKNGR 718
Query: 225 ISLLAQELDP 254
+S +E DP
Sbjct: 719 LS-CTRESDP 727
>DQ149927-1|ABA06534.1| 1064|Homo sapiens serine protease inhibitor
Kazal-type 5 protein.
Length = 1064
Score = 33.1 bits (72), Expect = 1.1
Identities = 18/70 (25%), Positives = 35/70 (50%)
Frame = +3
Query: 45 KSQSNVCVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSAECDQFVEKYADLV 224
K+ N C +C+ V ++ +++ K K +D+ A HG + EC ++ E+ +
Sbjct: 659 KTHGNKCAMCKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYQEQMKNGR 718
Query: 225 ISLLAQELDP 254
+S +E DP
Sbjct: 719 LS-CTRESDP 727
>AJ228139-1|CAB40839.1| 1064|Homo sapiens LEKTI precursor protein.
Length = 1064
Score = 33.1 bits (72), Expect = 1.1
Identities = 18/70 (25%), Positives = 35/70 (50%)
Frame = +3
Query: 45 KSQSNVCVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSAECDQFVEKYADLV 224
K+ N C +C+ V ++ +++ K K +D+ A HG + EC ++ E+ +
Sbjct: 659 KTHGNKCAMCKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYQEQMKNGR 718
Query: 225 ISLLAQELDP 254
+S +E DP
Sbjct: 719 LS-CTRESDP 727
>AJ391230-1|CAB96877.1| 1064|Homo sapiens serine protease inhibitor
Kazal type 5 protein.
Length = 1064
Score = 32.7 bits (71), Expect = 1.4
Identities = 18/70 (25%), Positives = 35/70 (50%)
Frame = +3
Query: 45 KSQSNVCVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSAECDQFVEKYADLV 224
K+ N C +C+ V ++ +++ K K +D+ A HG + EC ++ E+ +
Sbjct: 659 KTHGNKCAMCKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYREQMKNGR 718
Query: 225 ISLLAQELDP 254
+S +E DP
Sbjct: 719 LS-CTRESDP 727
>X54101-1|CAA38035.1| 145|Homo sapiens NKG5 product protein.
Length = 145
Score = 32.3 bits (70), Expect = 1.9
Identities = 16/75 (21%), Positives = 32/75 (42%)
Frame = +3
Query: 72 CEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSAECDQFVEKYADLVISLLAQELD 251
C +++++ + DK + A +C+ C F+ +Y V L
Sbjct: 69 CLTIVQKLKKMV-DKPTQRSVSNAATRVCRTGRSRWRDVCRNFMRRYQSRVTQGLVAGET 127
Query: 252 PSEVCEELKLCKPES 296
++CE+L+LC P +
Sbjct: 128 AQQICEDLRLCIPST 142
>CR541859-1|CAG46657.1| 145|Homo sapiens GNLY protein.
Length = 145
Score = 32.3 bits (70), Expect = 1.9
Identities = 16/75 (21%), Positives = 32/75 (42%)
Frame = +3
Query: 72 CEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSAECDQFVEKYADLVISLLAQELD 251
C +++++ + DK + A +C+ C F+ +Y V L
Sbjct: 69 CLTIVQKLKKMV-DKPTQRSVSNAATRVCRTGRSRWRDVCRNFMRRYQSRVTQGLVAGET 127
Query: 252 PSEVCEELKLCKPES 296
++CE+L+LC P +
Sbjct: 128 AQQICEDLRLCIPST 142
>BC023576-1|AAH23576.1| 145|Homo sapiens granulysin protein.
Length = 145
Score = 32.3 bits (70), Expect = 1.9
Identities = 16/75 (21%), Positives = 32/75 (42%)
Frame = +3
Query: 72 CEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSAECDQFVEKYADLVISLLAQELD 251
C +++++ + DK + A +C+ C F+ +Y V L
Sbjct: 69 CLTIVQKLKKMV-DKPTQRSVSNAATRVCRTGRSRWRDVCRNFMRRYQSRVTQGLVAGET 127
Query: 252 PSEVCEELKLCKPES 296
++CE+L+LC P +
Sbjct: 128 AQQICEDLRLCIPST 142
>M19097-1|AAA36628.1| 243|Homo sapiens protein ( Human pulmonary
surfactant apoprotein 18 (SP 18) mRNA, 3' end. ).
Length = 243
Score = 31.9 bits (69), Expect = 2.5
Identities = 33/166 (19%), Positives = 63/166 (37%), Gaps = 2/166 (1%)
Frame = +3
Query: 63 CVLCEFVLKEIDDQIKDKHNDDEIKKAVHGICKHMPKSVSAECDQFVEKYADLVISLLAQ 242
C LC ++K I I + AV +C+ +P C E+Y+ +++ L
Sbjct: 70 CWLCRALIKRIQAMIPK----GALAVAVAQVCRVVPLVAGGICQCLAERYSVILLDTLLG 125
Query: 243 ELDPSEVCEELKLCKPESXXXXXXXXXXXXCAVCET-VVMAVKKVLKNEKLDRNIVHIIE 419
+ P VC + C + E + M+V N ++ I +
Sbjct: 126 RMLPQLVCRLVLRCSMDDSAGPRSPTGEWLPRDSECHLCMSVTTQAGNSS-EQAIPQAML 184
Query: 420 KSCGLLPAKYNTRCYAMLEVYGESIIHLIEE-FGAKGVCQRIGFCG 554
++C + +C +E + ++ L+ + A CQ +G CG
Sbjct: 185 QAC-VGSWLDREKCKQFVEQHTPQLLTLVPRGWDAHTTCQALGVCG 229
>BC040609-1|AAH40609.1| 589|Homo sapiens SUMO1/sentrin/SMT3
specific peptidase 2 protein.
Length = 589
Score = 31.9 bits (69), Expect = 2.5
Identities = 17/56 (30%), Positives = 32/56 (57%), Gaps = 4/56 (7%)
Frame = +3
Query: 69 LCEFVLKEIDDQIKDKHNDD--EIKKAVHGICKH-MPKSVS-AECDQFVEKYADLV 224
+CE +L+ + D+ K K N D ++ H + H +P+ ++ ++C F KYAD +
Sbjct: 504 ICEILLQYLQDESKTKRNSDLNLLEWTHHSMKPHEIPQQLNGSDCGMFTCKYADYI 559
>AY584611-1|AAS91740.1| 2367|Homo sapiens GPR158-like 1 receptor
protein.
Length = 2367
Score = 31.9 bits (69), Expect = 2.5
Identities = 14/34 (41%), Positives = 22/34 (64%)
Frame = +2
Query: 203 REIRGFSHLSPRSRIGPERSLRRIEIMQTRITEN 304
RE++G S L PR+ + PE SL+ E + +TE+
Sbjct: 2310 RELQGPSGLEPRTSLAPEPSLQEAESQSSSLTED 2343
>AL834380-1|CAD39043.1| 587|Homo sapiens hypothetical protein
protein.
Length = 587
Score = 31.9 bits (69), Expect = 2.5
Identities = 17/56 (30%), Positives = 32/56 (57%), Gaps = 4/56 (7%)
Frame = +3
Query: 69 LCEFVLKEIDDQIKDKHNDD--EIKKAVHGICKH-MPKSVS-AECDQFVEKYADLV 224
+CE +L+ + D+ K K N D ++ H + H +P+ ++ ++C F KYAD +
Sbjct: 502 ICEILLQYLQDESKTKRNSDLNLLEWTHHSMKPHEIPQQLNGSDCGMFTCKYADYI 557
>AK027599-1|BAB55222.1| 589|Homo sapiens protein ( Homo sapiens
cDNA FLJ14693 fis, clone NT2RP2005360, weakly similar to
Homo sapiens sentrin/SUMO-specific protease (SENP1)
mRNA. ).
Length = 589
Score = 31.9 bits (69), Expect = 2.5
Identities = 17/56 (30%), Positives = 32/56 (57%), Gaps = 4/56 (7%)
Frame = +3
Query: 69 LCEFVLKEIDDQIKDKHNDD--EIKKAVHGICKH-MPKSVS-AECDQFVEKYADLV 224
+CE +L+ + D+ K K N D ++ H + H +P+ ++ ++C F KYAD +
Sbjct: 504 ICEILLQYLQDESKTKRNSDLNLLEWTHHSMKPHEIPQQLNGSDCGMFTCKYADYI 559
>AF151697-1|AAG15309.2| 590|Homo sapiens sentrin-specific protease
protein.
Length = 590
Score = 31.9 bits (69), Expect = 2.5
Identities = 17/56 (30%), Positives = 32/56 (57%), Gaps = 4/56 (7%)
Frame = +3
Query: 69 LCEFVLKEIDDQIKDKHNDD--EIKKAVHGICKH-MPKSVS-AECDQFVEKYADLV 224
+CE +L+ + D+ K K N D ++ H + H +P+ ++ ++C F KYAD +
Sbjct: 505 ICEILLQYLQDESKTKRNSDLNLLEWTHHSMKPHEIPQQLNGSDCGMFTCKYADYI 560
>AB037752-1|BAA92569.2| 589|Homo sapiens KIAA1331 protein protein.
Length = 589
Score = 31.9 bits (69), Expect = 2.5
Identities = 17/56 (30%), Positives = 32/56 (57%), Gaps = 4/56 (7%)
Frame = +3
Query: 69 LCEFVLKEIDDQIKDKHNDD--EIKKAVHGICKH-MPKSVS-AECDQFVEKYADLV 224
+CE +L+ + D+ K K N D ++ H + H +P+ ++ ++C F KYAD +
Sbjct: 504 ICEILLQYLQDESKTKRNSDLNLLEWTHHSMKPHEIPQQLNGSDCGMFTCKYADYI 559
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 94,318,657
Number of Sequences: 237096
Number of extensions: 1886672
Number of successful extensions: 4797
Number of sequences better than 10.0: 48
Number of HSP's better than 10.0 without gapping: 4403
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4744
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8959138240
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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