Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P07_F_N19
(574 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC024194-1|AAH24194.2| 340|Homo sapiens 3-hydroxymethyl-3-methy... 139 6e-33
AL590406-2|CAI40662.1| 241|Homo sapiens protein ( Human DNA seq... 139 6e-33
AF131827-1|AAD20054.1| 191|Homo sapiens Unknown protein. 139 6e-33
U49719-1|AAB19099.1| 305|Homo sapiens hydroxymethylglutaryl-CoA... 128 1e-29
L07033-1|AAA92733.1| 325|Homo sapiens hydroxymethylglutaryl-CoA... 128 1e-29
CR456884-1|CAG33165.1| 325|Homo sapiens HMGCL protein. 128 1e-29
BT009792-1|AAP88794.1| 325|Homo sapiens 3-hydroxymethyl-3-methy... 128 1e-29
BC010570-1|AAH10570.1| 325|Homo sapiens 3-hydroxymethyl-3-methy... 128 1e-29
AL031295-19|CAI23161.1| 300|Homo sapiens 3-hydroxymethyl-3-meth... 128 1e-29
AB051477-1|BAB21781.1| 482|Homo sapiens KIAA1690 protein protein. 35 0.23
AY358381-1|AAQ88747.1| 575|Homo sapiens KRSL1875 protein. 33 0.54
BC000568-1|AAH00568.1| 575|Homo sapiens transmembrane protein 1... 32 1.6
BC066643-1|AAH66643.1| 1202|Homo sapiens CASK interacting protei... 31 3.8
AK127587-1|BAC87045.1| 297|Homo sapiens protein ( Homo sapiens ... 31 3.8
AF451976-1|AAL49757.1| 1202|Homo sapiens cask-interacting protei... 31 3.8
AB032965-1|BAA86453.1| 1124|Homo sapiens KIAA1139 protein protein. 31 3.8
>BC024194-1|AAH24194.2| 340|Homo sapiens
3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase-like 1
protein.
Length = 340
Score = 139 bits (337), Expect = 6e-33
Identities = 62/110 (56%), Positives = 82/110 (74%)
Frame = +3
Query: 6 GRSGSVRRLLHEILTVAKPEQLALHFHDTYGQGLSNLLAGLEFGIKTVDSSISGLGGCPY 185
G GS++R+L ++ P LA+H HDTYGQ L+N+L L+ GI VDS++SGLGGCPY
Sbjct: 224 GTPGSMKRMLESVMKEIPPGALAVHCHDTYGQALANILTALQMGINVVDSAVSGLGGCPY 283
Query: 186 ARGASGNLATEDLVYFLYGLGVNTDVDLVKIIEAGRYISNFLGKPTESKV 335
A+GASGN+ATEDL+Y L GLG+NT V+L K++EAG +I + K T SKV
Sbjct: 284 AKGASGNVATEDLIYMLNGLGLNTGVNLYKVMEAGDFICKAVNKTTNSKV 333
>AL590406-2|CAI40662.1| 241|Homo sapiens protein ( Human DNA
sequence from clone RP11-418P12 on chromosome 6. ).
Length = 241
Score = 139 bits (337), Expect = 6e-33
Identities = 62/110 (56%), Positives = 82/110 (74%)
Frame = +3
Query: 6 GRSGSVRRLLHEILTVAKPEQLALHFHDTYGQGLSNLLAGLEFGIKTVDSSISGLGGCPY 185
G GS++R+L ++ P LA+H HDTYGQ L+N+L L+ GI VDS++SGLGGCPY
Sbjct: 125 GTPGSMKRMLESVMKEIPPGALAVHCHDTYGQALANILTALQMGINVVDSAVSGLGGCPY 184
Query: 186 ARGASGNLATEDLVYFLYGLGVNTDVDLVKIIEAGRYISNFLGKPTESKV 335
A+GASGN+ATEDL+Y L GLG+NT V+L K++EAG +I + K T SKV
Sbjct: 185 AKGASGNVATEDLIYMLNGLGLNTGVNLYKVMEAGDFICKAVNKTTNSKV 234
>AF131827-1|AAD20054.1| 191|Homo sapiens Unknown protein.
Length = 191
Score = 139 bits (337), Expect = 6e-33
Identities = 62/110 (56%), Positives = 82/110 (74%)
Frame = +3
Query: 6 GRSGSVRRLLHEILTVAKPEQLALHFHDTYGQGLSNLLAGLEFGIKTVDSSISGLGGCPY 185
G GS++R+L ++ P LA+H HDTYGQ L+N+L L+ GI VDS++SGLGGCPY
Sbjct: 75 GTPGSMKRMLESVMKEIPPGALAVHCHDTYGQALANILTALQMGINVVDSAVSGLGGCPY 134
Query: 186 ARGASGNLATEDLVYFLYGLGVNTDVDLVKIIEAGRYISNFLGKPTESKV 335
A+GASGN+ATEDL+Y L GLG+NT V+L K++EAG +I + K T SKV
Sbjct: 135 AKGASGNVATEDLIYMLNGLGLNTGVNLYKVMEAGDFICKAVNKTTNSKV 184
>U49719-1|AAB19099.1| 305|Homo sapiens hydroxymethylglutaryl-CoA
lyase protein.
Length = 305
Score = 128 bits (310), Expect = 1e-29
Identities = 59/110 (53%), Positives = 78/110 (70%)
Frame = +3
Query: 6 GRSGSVRRLLHEILTVAKPEQLALHFHDTYGQGLSNLLAGLEFGIKTVDSSISGLGGCPY 185
G G ++ +L ++ LA+H HDTYGQ L+N L L+ G+ VDSS++GLGGCPY
Sbjct: 189 GTPGIMKDMLSAVMQEVPLAALAVHCHDTYGQALANTLMALQMGVSVVDSSVAGLGGCPY 248
Query: 186 ARGASGNLATEDLVYFLYGLGVNTDVDLVKIIEAGRYISNFLGKPTESKV 335
A+GASGNLATEDLVY L GLG++T V+L K++EAG +I L + T SKV
Sbjct: 249 AQGASGNLATEDLVYMLEGLGIHTGVNLQKLLEAGNFICQALNRKTSSKV 298
>L07033-1|AAA92733.1| 325|Homo sapiens hydroxymethylglutaryl-CoA
lyase protein.
Length = 325
Score = 128 bits (310), Expect = 1e-29
Identities = 59/110 (53%), Positives = 78/110 (70%)
Frame = +3
Query: 6 GRSGSVRRLLHEILTVAKPEQLALHFHDTYGQGLSNLLAGLEFGIKTVDSSISGLGGCPY 185
G G ++ +L ++ LA+H HDTYGQ L+N L L+ G+ VDSS++GLGGCPY
Sbjct: 209 GTPGIMKDMLSAVMQEVPLAALAVHCHDTYGQALTNTLMALQMGVSVVDSSVAGLGGCPY 268
Query: 186 ARGASGNLATEDLVYFLYGLGVNTDVDLVKIIEAGRYISNFLGKPTESKV 335
A+GASGNLATEDLVY L GLG++T V+L K++EAG +I L + T SKV
Sbjct: 269 AQGASGNLATEDLVYMLEGLGIHTGVNLQKLLEAGNFICQALNRKTSSKV 318
>CR456884-1|CAG33165.1| 325|Homo sapiens HMGCL protein.
Length = 325
Score = 128 bits (310), Expect = 1e-29
Identities = 59/110 (53%), Positives = 78/110 (70%)
Frame = +3
Query: 6 GRSGSVRRLLHEILTVAKPEQLALHFHDTYGQGLSNLLAGLEFGIKTVDSSISGLGGCPY 185
G G ++ +L ++ LA+H HDTYGQ L+N L L+ G+ VDSS++GLGGCPY
Sbjct: 209 GTPGIMKDMLSAVMQEVPLAALAVHCHDTYGQALANTLMALQMGVSVVDSSVAGLGGCPY 268
Query: 186 ARGASGNLATEDLVYFLYGLGVNTDVDLVKIIEAGRYISNFLGKPTESKV 335
A+GASGNLATEDLVY L GLG++T V+L K++EAG +I L + T SKV
Sbjct: 269 AQGASGNLATEDLVYMLEGLGIHTGVNLQKLLEAGNFICQALNRKTSSKV 318
>BT009792-1|AAP88794.1| 325|Homo sapiens
3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase
(hydroxymethylglutaricaciduri protein.
Length = 325
Score = 128 bits (310), Expect = 1e-29
Identities = 59/110 (53%), Positives = 78/110 (70%)
Frame = +3
Query: 6 GRSGSVRRLLHEILTVAKPEQLALHFHDTYGQGLSNLLAGLEFGIKTVDSSISGLGGCPY 185
G G ++ +L ++ LA+H HDTYGQ L+N L L+ G+ VDSS++GLGGCPY
Sbjct: 209 GTPGIMKDMLSAVMQEVPLAALAVHCHDTYGQALANTLMALQMGVSVVDSSVAGLGGCPY 268
Query: 186 ARGASGNLATEDLVYFLYGLGVNTDVDLVKIIEAGRYISNFLGKPTESKV 335
A+GASGNLATEDLVY L GLG++T V+L K++EAG +I L + T SKV
Sbjct: 269 AQGASGNLATEDLVYMLEGLGIHTGVNLQKLLEAGNFICQALNRKTSSKV 318
>BC010570-1|AAH10570.1| 325|Homo sapiens
3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase
(hydroxymethylglutaricaciduri protein.
Length = 325
Score = 128 bits (310), Expect = 1e-29
Identities = 59/110 (53%), Positives = 78/110 (70%)
Frame = +3
Query: 6 GRSGSVRRLLHEILTVAKPEQLALHFHDTYGQGLSNLLAGLEFGIKTVDSSISGLGGCPY 185
G G ++ +L ++ LA+H HDTYGQ L+N L L+ G+ VDSS++GLGGCPY
Sbjct: 209 GTPGIMKDMLSAVMQEVPLAALAVHCHDTYGQALANTLMALQMGVSVVDSSVAGLGGCPY 268
Query: 186 ARGASGNLATEDLVYFLYGLGVNTDVDLVKIIEAGRYISNFLGKPTESKV 335
A+GASGNLATEDLVY L GLG++T V+L K++EAG +I L + T SKV
Sbjct: 269 AQGASGNLATEDLVYMLEGLGIHTGVNLQKLLEAGNFICQALNRKTSSKV 318
>AL031295-19|CAI23161.1| 300|Homo sapiens
3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyaseclass T
protein.
Length = 300
Score = 128 bits (310), Expect = 1e-29
Identities = 59/110 (53%), Positives = 78/110 (70%)
Frame = +3
Query: 6 GRSGSVRRLLHEILTVAKPEQLALHFHDTYGQGLSNLLAGLEFGIKTVDSSISGLGGCPY 185
G G ++ +L ++ LA+H HDTYGQ L+N L L+ G+ VDSS++GLGGCPY
Sbjct: 184 GTPGIMKDMLSAVMQEVPLAALAVHCHDTYGQALANTLMALQMGVSVVDSSVAGLGGCPY 243
Query: 186 ARGASGNLATEDLVYFLYGLGVNTDVDLVKIIEAGRYISNFLGKPTESKV 335
A+GASGNLATEDLVY L GLG++T V+L K++EAG +I L + T SKV
Sbjct: 244 AQGASGNLATEDLVYMLEGLGIHTGVNLQKLLEAGNFICQALNRKTSSKV 293
>AB051477-1|BAB21781.1| 482|Homo sapiens KIAA1690 protein protein.
Length = 482
Score = 34.7 bits (76), Expect = 0.23
Identities = 24/63 (38%), Positives = 33/63 (52%), Gaps = 4/63 (6%)
Frame = -1
Query: 271 TRSTSV--LTPRPYRK*TRSSVARLPLAPRAYGHPPSPEME--ESTVLIPNSRPASKLES 104
TR TSV LTP P ++++ L PRA GHPP+ + +TV P+S +S
Sbjct: 52 TRHTSVVMLTPNPDGPPSQAAAPMATLTPRAEGHPPTHTISTIAATVTAPHSE-SSLSTG 110
Query: 103 PCP 95
P P
Sbjct: 111 PAP 113
>AY358381-1|AAQ88747.1| 575|Homo sapiens KRSL1875 protein.
Length = 575
Score = 33.5 bits (73), Expect = 0.54
Identities = 24/63 (38%), Positives = 32/63 (50%), Gaps = 4/63 (6%)
Frame = -1
Query: 271 TRSTSV--LTPRPYRK*TRSSVARLPLAPRAYGHPPSPEME--ESTVLIPNSRPASKLES 104
TR TSV LTP P ++++ L PRA GHPP+ + +TV P S +S
Sbjct: 58 TRHTSVVMLTPNPDGPPSQAAAPMATLTPRAEGHPPTHTISTIAATVTAPYSE-SSLSTG 116
Query: 103 PCP 95
P P
Sbjct: 117 PAP 119
>BC000568-1|AAH00568.1| 575|Homo sapiens transmembrane protein 108
protein.
Length = 575
Score = 31.9 bits (69), Expect = 1.6
Identities = 23/63 (36%), Positives = 32/63 (50%), Gaps = 4/63 (6%)
Frame = -1
Query: 271 TRSTSV--LTPRPYRK*TRSSVARLPLAPRAYGHPPSPEME--ESTVLIPNSRPASKLES 104
TR TSV LTP P ++++ PRA GHPP+ + +TV P+S +S
Sbjct: 58 TRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIAATVTAPHSE-SSLSTG 116
Query: 103 PCP 95
P P
Sbjct: 117 PAP 119
>BC066643-1|AAH66643.1| 1202|Homo sapiens CASK interacting protein 2
protein.
Length = 1202
Score = 30.7 bits (66), Expect = 3.8
Identities = 22/66 (33%), Positives = 27/66 (40%)
Frame = -1
Query: 292 RPASIIFTRSTSVLTPRPYRK*TRSSVARLPLAPRAYGHPPSPEMEESTVLIPNSRPASK 113
RP R++ +TP P R RS L R G PP P S+V P+ P
Sbjct: 832 RPGRSALVRTSPSVTPTPARGTPRSQ--SFALRARRKGPPPPPPKRLSSVSGPSPEPPPL 889
Query: 112 LESPCP 95
SP P
Sbjct: 890 DGSPGP 895
>AK127587-1|BAC87045.1| 297|Homo sapiens protein ( Homo sapiens
cDNA FLJ45682 fis, clone FCBBF3001018, moderately
similar to Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4).
).
Length = 297
Score = 30.7 bits (66), Expect = 3.8
Identities = 12/29 (41%), Positives = 18/29 (62%)
Frame = +3
Query: 6 GRSGSVRRLLHEILTVAKPEQLALHFHDT 92
G GS++R+L ++ P LA+H HDT
Sbjct: 254 GTPGSMKRMLESVMKEIPPGALAVHCHDT 282
>AF451976-1|AAL49757.1| 1202|Homo sapiens cask-interacting protein 2
protein.
Length = 1202
Score = 30.7 bits (66), Expect = 3.8
Identities = 22/66 (33%), Positives = 27/66 (40%)
Frame = -1
Query: 292 RPASIIFTRSTSVLTPRPYRK*TRSSVARLPLAPRAYGHPPSPEMEESTVLIPNSRPASK 113
RP R++ +TP P R RS L R G PP P S+V P+ P
Sbjct: 832 RPGRSALVRTSPSVTPTPARGTPRSQ--SFALRARRKGPPPPPPKRLSSVSGPSPEPPPL 889
Query: 112 LESPCP 95
SP P
Sbjct: 890 DGSPGP 895
>AB032965-1|BAA86453.1| 1124|Homo sapiens KIAA1139 protein protein.
Length = 1124
Score = 30.7 bits (66), Expect = 3.8
Identities = 22/66 (33%), Positives = 27/66 (40%)
Frame = -1
Query: 292 RPASIIFTRSTSVLTPRPYRK*TRSSVARLPLAPRAYGHPPSPEMEESTVLIPNSRPASK 113
RP R++ +TP P R RS L R G PP P S+V P+ P
Sbjct: 754 RPGRSALVRTSPSVTPTPARGTPRSQ--SFALRARRKGPPPPPPKRLSSVSGPSPEPPPL 811
Query: 112 LESPCP 95
SP P
Sbjct: 812 DGSPGP 817
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 79,298,653
Number of Sequences: 237096
Number of extensions: 1676439
Number of successful extensions: 3811
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 3676
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3811
length of database: 76,859,062
effective HSP length: 86
effective length of database: 56,468,806
effective search space used: 5872755824
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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