Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P07_F_K08
(770 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein. 181 3e-45
CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein. 181 3e-45
BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase fam... 181 3e-45
BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase fam... 181 3e-45
BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase fam... 181 3e-45
AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase fam... 181 3e-45
AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase prot... 181 3e-45
AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase prot... 181 3e-45
U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase... 178 2e-44
S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase hom... 178 2e-44
L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol dehydrogenase... 178 2e-44
BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase fam... 178 2e-44
BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase fam... 178 2e-44
BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase fam... 178 2e-44
AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase fam... 178 2e-44
AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase fam... 178 2e-44
AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding prote... 178 2e-44
AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding prote... 178 2e-44
AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding p... 178 2e-44
U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol dehyd... 177 4e-44
U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase... 177 4e-44
M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase... 177 4e-44
BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase fam... 177 4e-44
BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase fam... 177 4e-44
BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase fam... 177 4e-44
BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase fam... 177 4e-44
AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase fam... 177 4e-44
AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid ... 177 4e-44
AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid... 177 4e-44
AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase fam... 176 6e-44
AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid d... 175 1e-43
S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase pro... 175 1e-43
D26125-1|BAA05122.1| 321|Homo sapiens 3 alpha-hydroxysteroid/di... 175 1e-43
AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase fam... 175 1e-43
AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid ... 175 1e-43
AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogena... 175 1e-43
AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogena... 175 1e-43
DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxystero... 175 2e-43
CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein. 174 3e-43
BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase fam... 174 3e-43
D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein. 174 3e-43
AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthas... 174 3e-43
AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein. 174 3e-43
BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase fam... 173 4e-43
BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase fam... 173 4e-43
BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase fam... 173 4e-43
AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase fam... 173 4e-43
S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase hom... 173 6e-43
L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid de... 173 6e-43
J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein. 173 6e-43
X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for ... 172 1e-42
S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase hom... 172 1e-42
M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein. 172 1e-42
M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose re... 172 1e-42
J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein. 172 1e-42
J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein. 172 1e-42
CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein. 172 1e-42
BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase fam... 172 1e-42
BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase fam... 172 1e-42
BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase fam... 172 1e-42
AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen HD-C... 172 1e-42
AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein. 172 1e-42
AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase fam... 172 1e-42
D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase... 167 4e-41
BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase fam... 167 5e-41
M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordeco... 165 2e-40
Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5 be... 164 3e-40
BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase fam... 164 3e-40
BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase fam... 164 3e-40
AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductas... 164 3e-40
U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like pep... 159 8e-39
CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein. 159 8e-39
BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase fam... 159 8e-39
BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase fam... 159 8e-39
AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase pro... 159 8e-39
AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase prot... 157 5e-38
AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase fam... 136 6e-32
AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase fam... 123 8e-28
AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase fam... 123 8e-28
BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein. 115 2e-25
AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase loo... 115 2e-25
AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase rel... 115 2e-25
BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase fam... 114 4e-25
BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase fam... 114 4e-25
AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens ... 114 4e-25
AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase fam... 112 1e-24
AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto red... 109 8e-24
AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase rel... 97 6e-20
AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase rel... 97 6e-20
AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase rel... 97 6e-20
AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens ... 65 2e-10
Y16675-1|CAA76347.1| 330|Homo sapiens aflatoxin B1-aldehyde red... 53 1e-06
BT007347-1|AAP36011.1| 330|Homo sapiens aldo-keto reductase fam... 53 1e-06
BC013996-1|AAH13996.1| 330|Homo sapiens AKR7A2 protein protein. 53 1e-06
BC012171-1|AAH12171.1| 330|Homo sapiens AKR7A2 protein protein. 53 1e-06
BC011586-1|AAH11586.1| 330|Homo sapiens AKR7A2 protein protein. 53 1e-06
BC010852-1|AAH10852.1| 330|Homo sapiens AKR7A2 protein protein. 53 1e-06
BC007352-1|AAH07352.2| 358|Homo sapiens AKR7A2 protein protein. 53 1e-06
BC004111-1|AAH04111.3| 330|Homo sapiens AKR7A2 protein protein. 53 1e-06
AL035413-8|CAB72321.1| 330|Homo sapiens aldo-keto reductase fam... 53 1e-06
AF026947-1|AAC52104.1| 330|Homo sapiens aflatoxin aldehyde redu... 53 1e-06
AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthas... 46 1e-04
AF040639-1|AAD02195.1| 331|Homo sapiens aflatoxin B1-aldehyde r... 45 3e-04
BC042420-1|AAH42420.2| 331|Homo sapiens aldo-keto reductase fam... 43 0.001
BC031562-1|AAH31562.1| 331|Homo sapiens aldo-keto reductase fam... 43 0.001
AJ271799-1|CAC81076.1| 331|Homo sapiens aflatoxin B1 aldehyde r... 43 0.001
BC025709-1|AAH25709.1| 331|Homo sapiens aldo-keto reductase fam... 42 0.002
AL035413-11|CAI22232.1| 331|Homo sapiens aldo-keto reductase fa... 42 0.002
AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto red... 41 0.004
AJ278012-1|CAC79668.1| 259|Homo sapiens aflatoxin B1 aldehyde r... 40 0.007
L35546-1|AAA65028.1| 274|Homo sapiens gamma-glutamylcysteine sy... 35 0.28
CR541833-1|CAG46632.1| 274|Homo sapiens GCLM protein. 35 0.28
BC041809-1|AAH41809.1| 274|Homo sapiens glutamate-cysteine liga... 35 0.28
AY773965-1|AAV28733.1| 274|Homo sapiens glutamate-cysteine liga... 35 0.28
AL117351-10|CAI22976.1| 274|Homo sapiens glutamate-cysteine lig... 35 0.28
AL049796-2|CAI21813.1| 274|Homo sapiens glutamate-cysteine liga... 35 0.28
>J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein.
Length = 325
Score = 181 bits (440), Expect = 3e-45
Identities = 95/245 (38%), Positives = 146/245 (59%), Gaps = 12/245 (4%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
+ L+ G +P++ LGT + +V+ AV +A+ GYRHID AA+Y +E ++G+
Sbjct: 6 VLLHTGQKMPLIGLGTWKSEP------GQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEA 59
Query: 244 IAEAIANG-LVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 420
+ E + G V REELFVT+KLWN KH + V PAL+++L L L+Y+DLYL+H+P A +
Sbjct: 60 LKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFE 119
Query: 421 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR 567
D+P D+ Y ETW+ ++ GL +++G+SNFN+ QI ++S + +R
Sbjct: 120 RGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVR 179
Query: 568 PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALAN 747
P + Q+E +P Q L+AHCQ+ G+ V AYSP G + P ++P + ALA
Sbjct: 180 PAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAE 239
Query: 748 KYRXS 762
KY S
Sbjct: 240 KYGRS 244
>CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein.
Length = 325
Score = 181 bits (440), Expect = 3e-45
Identities = 95/245 (38%), Positives = 146/245 (59%), Gaps = 12/245 (4%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
+ L+ G +P++ LGT + +V+ AV +A+ GYRHID AA+Y +E ++G+
Sbjct: 6 VLLHTGQKMPLIGLGTWKSEP------GQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEA 59
Query: 244 IAEAIANG-LVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 420
+ E + G V REELFVT+KLWN KH + V PAL+++L L L+Y+DLYL+H+P A +
Sbjct: 60 LKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFE 119
Query: 421 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR 567
D+P D+ Y ETW+ ++ GL +++G+SNFN+ QI ++S + +R
Sbjct: 120 RGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVR 179
Query: 568 PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALAN 747
P + Q+E +P Q L+AHCQ+ G+ V AYSP G + P ++P + ALA
Sbjct: 180 PAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAE 239
Query: 748 KYRXS 762
KY S
Sbjct: 240 KYGRS 244
>BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 181 bits (440), Expect = 3e-45
Identities = 95/245 (38%), Positives = 146/245 (59%), Gaps = 12/245 (4%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
+ L+ G +P++ LGT + +V+ AV +A+ GYRHID AA+Y +E ++G+
Sbjct: 6 VLLHTGQKMPLIGLGTWKSEP------GQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEA 59
Query: 244 IAEAIANG-LVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 420
+ E + G V REELFVT+KLWN KH + V PAL+++L L L+Y+DLYL+H+P A +
Sbjct: 60 LKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFE 119
Query: 421 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR 567
D+P D+ Y ETW+ ++ GL +++G+SNFN+ QI ++S + +R
Sbjct: 120 RGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVR 179
Query: 568 PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALAN 747
P + Q+E +P Q L+AHCQ+ G+ V AYSP G + P ++P + ALA
Sbjct: 180 PAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAE 239
Query: 748 KYRXS 762
KY S
Sbjct: 240 KYGRS 244
>BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 181 bits (440), Expect = 3e-45
Identities = 95/245 (38%), Positives = 146/245 (59%), Gaps = 12/245 (4%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
+ L+ G +P++ LGT + +V+ AV +A+ GYRHID AA+Y +E ++G+
Sbjct: 6 VLLHTGQKMPLIGLGTWKSEP------GQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEA 59
Query: 244 IAEAIANG-LVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 420
+ E + G V REELFVT+KLWN KH + V PAL+++L L L+Y+DLYL+H+P A +
Sbjct: 60 LKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFE 119
Query: 421 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR 567
D+P D+ Y ETW+ ++ GL +++G+SNFN+ QI ++S + +R
Sbjct: 120 RGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVR 179
Query: 568 PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALAN 747
P + Q+E +P Q L+AHCQ+ G+ V AYSP G + P ++P + ALA
Sbjct: 180 PAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAE 239
Query: 748 KYRXS 762
KY S
Sbjct: 240 KYGRS 244
>BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 181 bits (440), Expect = 3e-45
Identities = 95/245 (38%), Positives = 146/245 (59%), Gaps = 12/245 (4%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
+ L+ G +P++ LGT + +V+ AV +A+ GYRHID AA+Y +E ++G+
Sbjct: 6 VLLHTGQKMPLIGLGTWKSEP------GQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEA 59
Query: 244 IAEAIANG-LVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 420
+ E + G V REELFVT+KLWN KH + V PAL+++L L L+Y+DLYL+H+P A +
Sbjct: 60 LKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFE 119
Query: 421 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR 567
D+P D+ Y ETW+ ++ GL +++G+SNFN+ QI ++S + +R
Sbjct: 120 RGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVR 179
Query: 568 PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALAN 747
P + Q+E +P Q L+AHCQ+ G+ V AYSP G + P ++P + ALA
Sbjct: 180 PAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAE 239
Query: 748 KYRXS 762
KY S
Sbjct: 240 KYGRS 244
>AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydetase, 1 protein.
Length = 325
Score = 181 bits (440), Expect = 3e-45
Identities = 95/245 (38%), Positives = 146/245 (59%), Gaps = 12/245 (4%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
+ L+ G +P++ LGT + +V+ AV +A+ GYRHID AA+Y +E ++G+
Sbjct: 6 VLLHTGQKMPLIGLGTWKSEP------GQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEA 59
Query: 244 IAEAIANG-LVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 420
+ E + G V REELFVT+KLWN KH + V PAL+++L L L+Y+DLYL+H+P A +
Sbjct: 60 LKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFE 119
Query: 421 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR 567
D+P D+ Y ETW+ ++ GL +++G+SNFN+ QI ++S + +R
Sbjct: 120 RGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVR 179
Query: 568 PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALAN 747
P + Q+E +P Q L+AHCQ+ G+ V AYSP G + P ++P + ALA
Sbjct: 180 PAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAE 239
Query: 748 KYRXS 762
KY S
Sbjct: 240 KYGRS 244
>AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 181 bits (440), Expect = 3e-45
Identities = 95/245 (38%), Positives = 146/245 (59%), Gaps = 12/245 (4%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
+ L+ G +P++ LGT + +V+ AV +A+ GYRHID AA+Y +E ++G+
Sbjct: 6 VLLHTGQKMPLIGLGTWKSEP------GQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEA 59
Query: 244 IAEAIANG-LVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 420
+ E + G V REELFVT+KLWN KH + V PAL+++L L L+Y+DLYL+H+P A +
Sbjct: 60 LKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFE 119
Query: 421 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR 567
D+P D+ Y ETW+ ++ GL +++G+SNFN+ QI ++S + +R
Sbjct: 120 RGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVR 179
Query: 568 PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALAN 747
P + Q+E +P Q L+AHCQ+ G+ V AYSP G + P ++P + ALA
Sbjct: 180 PAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAE 239
Query: 748 KYRXS 762
KY S
Sbjct: 240 KYGRS 244
>AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 181 bits (440), Expect = 3e-45
Identities = 95/245 (38%), Positives = 146/245 (59%), Gaps = 12/245 (4%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
+ L+ G +P++ LGT + +V+ AV +A+ GYRHID AA+Y +E ++G+
Sbjct: 6 VLLHTGQKMPLIGLGTWKSEP------GQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEA 59
Query: 244 IAEAIANG-LVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 420
+ E + G V REELFVT+KLWN KH + V PAL+++L L L+Y+DLYL+H+P A +
Sbjct: 60 LKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFE 119
Query: 421 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR 567
D+P D+ Y ETW+ ++ GL +++G+SNFN+ QI ++S + +R
Sbjct: 120 RGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVR 179
Query: 568 PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALAN 747
P + Q+E +P Q L+AHCQ+ G+ V AYSP G + P ++P + ALA
Sbjct: 180 PAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAE 239
Query: 748 KYRXS 762
KY S
Sbjct: 240 KYGRS 244
>U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 178 bits (433), Expect = 2e-44
Identities = 99/245 (40%), Positives = 142/245 (57%), Gaps = 14/245 (5%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
++LNDG+ +P++ GT A + +AV AIEAG+ HID+A VY +EEQVG
Sbjct: 8 VKLNDGHFMPVLGFGT---YAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLA 64
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 423
I IA+G V RE++F T+KLW++ H + V PAL+ SLK L LDY+DLYLIHFP++ KP
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP 124
Query: 424 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 564
+ D +D TW+ M+ + GLA+SIGVSNFN + +++ +
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKY 184
Query: 565 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGA-PPPRSDDPTLTAL 741
+PV NQ+E +P Q L+ C+S I ++AYS G P +DP L AL
Sbjct: 185 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCAL 244
Query: 742 ANKYR 756
A K++
Sbjct: 245 AKKHK 249
>S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 178 bits (433), Expect = 2e-44
Identities = 99/245 (40%), Positives = 142/245 (57%), Gaps = 14/245 (5%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
++LNDG+ +P++ GT A + +AV AIEAG+ HID+A VY +EEQVG
Sbjct: 8 VKLNDGHFMPVLGFGT---YAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLA 64
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 423
I IA+G V RE++F T+KLW++ H + V PAL+ SLK L LDY+DLYLIHFP++ KP
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP 124
Query: 424 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR- 567
+ D +D TW+ M+ + GLA+SIGVSNFN + +++ ++
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEPGLKY 184
Query: 568 -PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGA-PPPRSDDPTLTAL 741
PV NQ+E +P Q L+ C+S I ++AYS G P +DP L AL
Sbjct: 185 EPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCAL 244
Query: 742 ANKYR 756
A K++
Sbjct: 245 AKKHK 249
>L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol
dehydrogenase/bile acid-binding protein protein.
Length = 323
Score = 178 bits (433), Expect = 2e-44
Identities = 100/245 (40%), Positives = 141/245 (57%), Gaps = 14/245 (5%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
++LNDG+ +P++ GT A + +AV AIEAGY HID+A VY +EEQVG
Sbjct: 8 VKLNDGHFMPVLGFGT---YAPAEVPKSKALEAVKLAIEAGYHHIDSAHVYNNEEQVGLA 64
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 423
I IA+G V RE++F T+KLW++ H + V PAL+ SLK L LDY DLYLIHFP++ KP
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYADLYLIHFPVSVKP 124
Query: 424 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR- 567
+ D +D TW+ M+ + GLA+SIGVSNFN + +++ ++
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEPGLKY 184
Query: 568 -PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGA-PPPRSDDPTLTAL 741
PV NQ+E +P Q L+ C+S I ++AYS G P +DP L AL
Sbjct: 185 EPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCAL 244
Query: 742 ANKYR 756
A K++
Sbjct: 245 AKKHK 249
>BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 178 bits (433), Expect = 2e-44
Identities = 99/245 (40%), Positives = 142/245 (57%), Gaps = 14/245 (5%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
++LNDG+ +P++ GT A + +AV AIEAG+ HID+A VY +EEQVG
Sbjct: 8 VKLNDGHFMPVLGFGT---YAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLA 64
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 423
I IA+G V RE++F T+KLW++ H + V PAL+ SLK L LDY+DLYLIHFP++ KP
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP 124
Query: 424 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 564
+ D +D TW+ M+ + GLA+SIGVSNFN + +++ +
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKY 184
Query: 565 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGA-PPPRSDDPTLTAL 741
+PV NQ+E +P Q L+ C+S I ++AYS G P +DP L AL
Sbjct: 185 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCAL 244
Query: 742 ANKYR 756
A K++
Sbjct: 245 AKKHK 249
>BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 178 bits (433), Expect = 2e-44
Identities = 99/245 (40%), Positives = 142/245 (57%), Gaps = 14/245 (5%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
++LNDG+ +P++ GT A + +AV AIEAG+ HID+A VY +EEQVG
Sbjct: 8 VKLNDGHFMPVLGFGT---YAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLA 64
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 423
I IA+G V RE++F T+KLW++ H + V PAL+ SLK L LDY+DLYLIHFP++ KP
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP 124
Query: 424 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 564
+ D +D TW+ M+ + GLA+SIGVSNFN + +++ +
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKY 184
Query: 565 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGA-PPPRSDDPTLTAL 741
+PV NQ+E +P Q L+ C+S I ++AYS G P +DP L AL
Sbjct: 185 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCAL 244
Query: 742 ANKYR 756
A K++
Sbjct: 245 AKKHK 249
>BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 178 bits (433), Expect = 2e-44
Identities = 99/245 (40%), Positives = 142/245 (57%), Gaps = 14/245 (5%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
++LNDG+ +P++ GT A + +AV AIEAG+ HID+A VY +EEQVG
Sbjct: 8 VKLNDGHFMPVLGFGT---YAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLA 64
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 423
I IA+G V RE++F T+KLW++ H + V PAL+ SLK L LDY+DLYLIHFP++ KP
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP 124
Query: 424 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 564
+ D +D TW+ M+ + GLA+SIGVSNFN + +++ +
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKY 184
Query: 565 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGA-PPPRSDDPTLTAL 741
+PV NQ+E +P Q L+ C+S I ++AYS G P +DP L AL
Sbjct: 185 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCAL 244
Query: 742 ANKYR 756
A K++
Sbjct: 245 AKKHK 249
>AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 178 bits (433), Expect = 2e-44
Identities = 99/245 (40%), Positives = 142/245 (57%), Gaps = 14/245 (5%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
++LNDG+ +P++ GT A + +AV AIEAG+ HID+A VY +EEQVG
Sbjct: 8 VKLNDGHFMPVLGFGT---YAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLA 64
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 423
I IA+G V RE++F T+KLW++ H + V PAL+ SLK L LDY+DLYLIHFP++ KP
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP 124
Query: 424 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 564
+ D +D TW+ M+ + GLA+SIGVSNFN + +++ +
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKY 184
Query: 565 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGA-PPPRSDDPTLTAL 741
+PV NQ+E +P Q L+ C+S I ++AYS G P +DP L AL
Sbjct: 185 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCAL 244
Query: 742 ANKYR 756
A K++
Sbjct: 245 AKKHK 249
>AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 178 bits (433), Expect = 2e-44
Identities = 99/245 (40%), Positives = 142/245 (57%), Gaps = 14/245 (5%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
++LNDG+ +P++ GT A + +AV AIEAG+ HID+A VY +EEQVG
Sbjct: 8 VKLNDGHFMPVLGFGT---YAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLA 64
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 423
I IA+G V RE++F T+KLW++ H + V PAL+ SLK L LDY+DLYLIHFP++ KP
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP 124
Query: 424 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 564
+ D +D TW+ M+ + GLA+SIGVSNFN + +++ +
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKY 184
Query: 565 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGA-PPPRSDDPTLTAL 741
+PV NQ+E +P Q L+ C+S I ++AYS G P +DP L AL
Sbjct: 185 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCAL 244
Query: 742 ANKYR 756
A K++
Sbjct: 245 AKKHK 249
>AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 178 bits (433), Expect = 2e-44
Identities = 99/245 (40%), Positives = 142/245 (57%), Gaps = 14/245 (5%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
++LNDG+ +P++ GT A + +AV AIEAG+ HID+A VY +EEQVG
Sbjct: 8 VKLNDGHFMPVLGFGT---YAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLA 64
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 423
I IA+G V RE++F T+KLW++ H + V PAL+ SLK L LDY+DLYLIHFP++ KP
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP 124
Query: 424 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 564
+ D +D TW+ M+ + GLA+SIGVSNFN + +++ +
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKY 184
Query: 565 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGA-PPPRSDDPTLTAL 741
+PV NQ+E +P Q L+ C+S I ++AYS G P +DP L AL
Sbjct: 185 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCAL 244
Query: 742 ANKYR 756
A K++
Sbjct: 245 AKKHK 249
>AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 178 bits (433), Expect = 2e-44
Identities = 99/245 (40%), Positives = 142/245 (57%), Gaps = 14/245 (5%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
++LNDG+ +P++ GT A + +AV AIEAG+ HID+A VY +EEQVG
Sbjct: 8 VKLNDGHFMPVLGFGT---YAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLA 64
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 423
I IA+G V RE++F T+KLW++ H + V PAL+ SLK L LDY+DLYLIHFP++ KP
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP 124
Query: 424 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 564
+ D +D TW+ M+ + GLA+SIGVSNFN + +++ +
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKY 184
Query: 565 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGA-PPPRSDDPTLTAL 741
+PV NQ+E +P Q L+ C+S I ++AYS G P +DP L AL
Sbjct: 185 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCAL 244
Query: 742 ANKYR 756
A K++
Sbjct: 245 AKKHK 249
>AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding
protein/AKR1C2/3alpha-hydroxysteroid dehydrogenase type
3 protein.
Length = 323
Score = 178 bits (433), Expect = 2e-44
Identities = 99/245 (40%), Positives = 142/245 (57%), Gaps = 14/245 (5%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
++LNDG+ +P++ GT A + +AV AIEAG+ HID+A VY +EEQVG
Sbjct: 8 VKLNDGHFMPVLGFGT---YAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLA 64
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 423
I IA+G V RE++F T+KLW++ H + V PAL+ SLK L LDY+DLYLIHFP++ KP
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP 124
Query: 424 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 564
+ D +D TW+ M+ + GLA+SIGVSNFN + +++ +
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKY 184
Query: 565 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGA-PPPRSDDPTLTAL 741
+PV NQ+E +P Q L+ C+S I ++AYS G P +DP L AL
Sbjct: 185 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCAL 244
Query: 742 ANKYR 756
A K++
Sbjct: 245 AKKHK 249
>U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol
dehydrogenase protein.
Length = 323
Score = 177 bits (431), Expect = 4e-44
Identities = 98/245 (40%), Positives = 142/245 (57%), Gaps = 14/245 (5%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
++LNDG+ +P++ GT A + +A AIEAG+RHID+A +Y +EEQVG
Sbjct: 8 VKLNDGHFMPVLGFGT---YAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 423
I IA+G V RE++F T+KLW + H + V PAL+ SLK L LDY+DLYLIHFP++ KP
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP 124
Query: 424 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 564
+ D +D TW+ ++ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184
Query: 565 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGA-PPPRSDDPTLTAL 741
+PV NQ+E +P Q L+ C+S I ++AYS G P +DP L AL
Sbjct: 185 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCAL 244
Query: 742 ANKYR 756
A K++
Sbjct: 245 AKKHK 249
>U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 177 bits (431), Expect = 4e-44
Identities = 98/245 (40%), Positives = 142/245 (57%), Gaps = 14/245 (5%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
++LNDG+ +P++ GT A + +A AIEAG+RHID+A +Y +EEQVG
Sbjct: 8 VKLNDGHFMPVLGFGT---YAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 423
I IA+G V RE++F T+KLW + H + V PAL+ SLK L LDY+DLYLIHFP++ KP
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP 124
Query: 424 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 564
+ D +D TW+ ++ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184
Query: 565 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGA-PPPRSDDPTLTAL 741
+PV NQ+E +P Q L+ C+S I ++AYS G P +DP L AL
Sbjct: 185 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCAL 244
Query: 742 ANKYR 756
A K++
Sbjct: 245 AKKHK 249
>M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 177 bits (431), Expect = 4e-44
Identities = 98/245 (40%), Positives = 142/245 (57%), Gaps = 14/245 (5%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
++LNDG+ +P++ GT A + +A AIEAG+RHID+A +Y +EEQVG
Sbjct: 8 VKLNDGHFMPVLGFGT---YAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 423
I IA+G V RE++F T+KLW + H + V PAL+ SLK L LDY+DLYLIHFP++ KP
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP 124
Query: 424 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 564
+ D +D TW+ ++ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184
Query: 565 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGA-PPPRSDDPTLTAL 741
+PV NQ+E +P Q L+ C+S I ++AYS G P +DP L AL
Sbjct: 185 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCAL 244
Query: 742 ANKYR 756
A K++
Sbjct: 245 AKKHK 249
>BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 177 bits (431), Expect = 4e-44
Identities = 98/245 (40%), Positives = 142/245 (57%), Gaps = 14/245 (5%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
++LNDG+ +P++ GT A + +A AIEAG+RHID+A +Y +EEQVG
Sbjct: 8 VKLNDGHFMPVLGFGT---YAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 423
I IA+G V RE++F T+KLW + H + V PAL+ SLK L LDY+DLYLIHFP++ KP
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP 124
Query: 424 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 564
+ D +D TW+ ++ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184
Query: 565 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGA-PPPRSDDPTLTAL 741
+PV NQ+E +P Q L+ C+S I ++AYS G P +DP L AL
Sbjct: 185 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCAL 244
Query: 742 ANKYR 756
A K++
Sbjct: 245 AKKHK 249
>BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 177 bits (431), Expect = 4e-44
Identities = 98/245 (40%), Positives = 142/245 (57%), Gaps = 14/245 (5%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
++LNDG+ +P++ GT A + +A AIEAG+RHID+A +Y +EEQVG
Sbjct: 8 VKLNDGHFMPVLGFGT---YAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 423
I IA+G V RE++F T+KLW + H + V PAL+ SLK L LDY+DLYLIHFP++ KP
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP 124
Query: 424 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 564
+ D +D TW+ ++ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184
Query: 565 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGA-PPPRSDDPTLTAL 741
+PV NQ+E +P Q L+ C+S I ++AYS G P +DP L AL
Sbjct: 185 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCAL 244
Query: 742 ANKYR 756
A K++
Sbjct: 245 AKKHK 249
>BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 177 bits (431), Expect = 4e-44
Identities = 98/245 (40%), Positives = 142/245 (57%), Gaps = 14/245 (5%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
++LNDG+ +P++ GT A + +A AIEAG+RHID+A +Y +EEQVG
Sbjct: 8 VKLNDGHFMPVLGFGT---YAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 423
I IA+G V RE++F T+KLW + H + V PAL+ SLK L LDY+DLYLIHFP++ KP
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP 124
Query: 424 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 564
+ D +D TW+ ++ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184
Query: 565 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGA-PPPRSDDPTLTAL 741
+PV NQ+E +P Q L+ C+S I ++AYS G P +DP L AL
Sbjct: 185 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCAL 244
Query: 742 ANKYR 756
A K++
Sbjct: 245 AKKHK 249
>BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 177 bits (431), Expect = 4e-44
Identities = 98/245 (40%), Positives = 142/245 (57%), Gaps = 14/245 (5%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
++LNDG+ +P++ GT A + +A AIEAG+RHID+A +Y +EEQVG
Sbjct: 8 VKLNDGHFMPVLGFGT---YAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 423
I IA+G V RE++F T+KLW + H + V PAL+ SLK L LDY+DLYLIHFP++ KP
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP 124
Query: 424 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 564
+ D +D TW+ ++ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184
Query: 565 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGA-PPPRSDDPTLTAL 741
+PV NQ+E +P Q L+ C+S I ++AYS G P +DP L AL
Sbjct: 185 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCAL 244
Query: 742 ANKYR 756
A K++
Sbjct: 245 AKKHK 249
>AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 177 bits (431), Expect = 4e-44
Identities = 98/245 (40%), Positives = 142/245 (57%), Gaps = 14/245 (5%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
++LNDG+ +P++ GT A + +A AIEAG+RHID+A +Y +EEQVG
Sbjct: 8 VKLNDGHFMPVLGFGT---YAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 423
I IA+G V RE++F T+KLW + H + V PAL+ SLK L LDY+DLYLIHFP++ KP
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP 124
Query: 424 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 564
+ D +D TW+ ++ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184
Query: 565 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGA-PPPRSDDPTLTAL 741
+PV NQ+E +P Q L+ C+S I ++AYS G P +DP L AL
Sbjct: 185 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCAL 244
Query: 742 ANKYR 756
A K++
Sbjct: 245 AKKHK 249
>AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 177 bits (431), Expect = 4e-44
Identities = 98/245 (40%), Positives = 142/245 (57%), Gaps = 14/245 (5%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
++LNDG+ +P++ GT A + +A AIEAG+RHID+A +Y +EEQVG
Sbjct: 8 VKLNDGHFMPVLGFGT---YAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 423
I IA+G V RE++F T+KLW + H + V PAL+ SLK L LDY+DLYLIHFP++ KP
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP 124
Query: 424 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 564
+ D +D TW+ ++ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184
Query: 565 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGA-PPPRSDDPTLTAL 741
+PV NQ+E +P Q L+ C+S I ++AYS G P +DP L AL
Sbjct: 185 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCAL 244
Query: 742 ANKYR 756
A K++
Sbjct: 245 AKKHK 249
>AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 177 bits (431), Expect = 4e-44
Identities = 98/245 (40%), Positives = 142/245 (57%), Gaps = 14/245 (5%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
++LNDG+ +P++ GT A + +A AIEAG+RHID+A +Y +EEQVG
Sbjct: 8 VKLNDGHFMPVLGFGT---YAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 423
I IA+G V RE++F T+KLW + H + V PAL+ SLK L LDY+DLYLIHFP++ KP
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP 124
Query: 424 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 564
+ D +D TW+ ++ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 125 GEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184
Query: 565 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGA-PPPRSDDPTLTAL 741
+PV NQ+E +P Q L+ C+S I ++AYS G P +DP L AL
Sbjct: 185 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCAL 244
Query: 742 ANKYR 756
A K++
Sbjct: 245 AKKHK 249
>AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase family
1, member C2 variant protein.
Length = 286
Score = 176 bits (429), Expect = 6e-44
Identities = 99/243 (40%), Positives = 140/243 (57%), Gaps = 14/243 (5%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
++LNDG+ +P++ GT A + +AV AIEAG+ HID+A VY +EEQVG
Sbjct: 21 VKLNDGHFMPVLGFGT---YAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLA 77
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 423
I IA+G V RE++F T+KLW++ H + V PAL+ SLK L LDY+DLYLIHFP++ KP
Sbjct: 78 IRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP 137
Query: 424 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 564
+ D +D TW+ M+ + GLA+SIGVSNFN + +++ +
Sbjct: 138 GEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKY 197
Query: 565 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGA-PPPRSDDPTLTAL 741
+PV NQ+E +P Q L+ C+S I ++AYS G P +DP L AL
Sbjct: 198 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCAL 257
Query: 742 ANK 750
A K
Sbjct: 258 AKK 260
>AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 175 bits (427), Expect = 1e-43
Identities = 99/245 (40%), Positives = 143/245 (58%), Gaps = 14/245 (5%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
++LNDG+ +P++ GT + EV + AIEAG+RHID+A +Y +EEQVG
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKL---AIEAGFRHIDSAYLYNNEEQVGLA 64
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 423
I IA+G V RE++F T+KLW V PAL+ SLKKL LDY+DLYL+HFP+A KP
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKP 124
Query: 424 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 564
++P D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 125 GETPLPKDENGKVIFDTVDLCATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKY 184
Query: 565 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGA-PPPRSDDPTLTAL 741
+PV NQ+E +P Q L+ C+S I ++A+S G + P +DP L AL
Sbjct: 185 KPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCAL 244
Query: 742 ANKYR 756
A K++
Sbjct: 245 AKKHK 249
>S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase
protein.
Length = 323
Score = 175 bits (426), Expect = 1e-43
Identities = 99/245 (40%), Positives = 143/245 (58%), Gaps = 14/245 (5%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
++LNDG+ +P++ GT + EV + AIEAG+RHID+A +Y +EEQVG
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKL---AIEAGFRHIDSAYLYNNEEQVGLA 64
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 423
I IA+G V RE++F T+KLW V PAL+ SLKKL LDY+DLYL+HFP+A KP
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKP 124
Query: 424 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 564
++P D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 125 GETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKY 184
Query: 565 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGA-PPPRSDDPTLTAL 741
+PV NQ+E +P Q L+ C+S I ++A+S G + P +DP L AL
Sbjct: 185 KPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCAL 244
Query: 742 ANKYR 756
A K++
Sbjct: 245 AKKHK 249
>D26125-1|BAA05122.1| 321|Homo sapiens 3
alpha-hydroxysteroid/dihydrodiol dehydrogenase DD4
protein.
Length = 321
Score = 175 bits (426), Expect = 1e-43
Identities = 99/245 (40%), Positives = 143/245 (58%), Gaps = 14/245 (5%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
++LNDG+ +P++ GT + EV + AIEAG+RHID+A +Y +EEQVG
Sbjct: 6 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKL---AIEAGFRHIDSAYLYNNEEQVGLA 62
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 423
I IA+G V RE++F T+KLW V PAL+ SLKKL LDY+DLYL+HFP+A KP
Sbjct: 63 IRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKP 122
Query: 424 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 564
++P D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 123 GETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKY 182
Query: 565 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGA-PPPRSDDPTLTAL 741
+PV NQ+E +P Q L+ C+S I ++A+S G + P +DP L AL
Sbjct: 183 KPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCAL 242
Query: 742 ANKYR 756
A K++
Sbjct: 243 AKKHK 247
>AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 175 bits (426), Expect = 1e-43
Identities = 99/245 (40%), Positives = 143/245 (58%), Gaps = 14/245 (5%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
++LNDG+ +P++ GT + EV + AIEAG+RHID+A +Y +EEQVG
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKL---AIEAGFRHIDSAYLYNNEEQVGLA 64
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 423
I IA+G V RE++F T+KLW V PAL+ SLKKL LDY+DLYL+HFP+A KP
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKP 124
Query: 424 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 564
++P D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 125 GETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKY 184
Query: 565 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGA-PPPRSDDPTLTAL 741
+PV NQ+E +P Q L+ C+S I ++A+S G + P +DP L AL
Sbjct: 185 KPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCAL 244
Query: 742 ANKYR 756
A K++
Sbjct: 245 AKKHK 249
>AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase type IIb protein.
Length = 323
Score = 175 bits (426), Expect = 1e-43
Identities = 101/249 (40%), Positives = 145/249 (58%), Gaps = 14/249 (5%)
Frame = +1
Query: 52 KRLVIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQ 231
K+ ++LNDG+ +P++ GT EV + AIEAG+RHID+A +Y +EEQ
Sbjct: 4 KQQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVSKL---AIEAGFRHIDSAHLYNNEEQ 60
Query: 232 VGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 411
VG I IA+G V RE++F T+KLW+ H + V PAL+ SLKK LDY+DLYLIH P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSTSHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120
Query: 412 ATKPDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 558
+ KP + SP D +D TW+ M+ + GLA+SIGVSNFN Q+ +++
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 559 YI--RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFV-VSRGQTGAPPPRSDDPT 729
+ +PV NQ+E +P + L+ C+S I ++AYS G R P +DP
Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240
Query: 730 LTALANKYR 756
L ALA K++
Sbjct: 241 LCALAKKHK 249
>AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 175 bits (426), Expect = 1e-43
Identities = 99/245 (40%), Positives = 143/245 (58%), Gaps = 14/245 (5%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
++LNDG+ +P++ GT + EV + AIEAG+RHID+A +Y +EEQVG
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKL---AIEAGFRHIDSAYLYNNEEQVGLA 64
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 423
I IA+G V RE++F T+KLW V PAL+ SLKKL LDY+DLYL+HFP+A KP
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKP 124
Query: 424 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 564
++P D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 125 GETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKY 184
Query: 565 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGA-PPPRSDDPTLTAL 741
+PV NQ+E +P Q L+ C+S I ++A+S G + P +DP L AL
Sbjct: 185 KPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCAL 244
Query: 742 ANKYR 756
A K++
Sbjct: 245 AKKHK 249
>AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 175 bits (426), Expect = 1e-43
Identities = 99/245 (40%), Positives = 143/245 (58%), Gaps = 14/245 (5%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
++LNDG+ +P++ GT + EV + AIEAG+RHID+A +Y +EEQVG
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKL---AIEAGFRHIDSAYLYNNEEQVGLA 64
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 423
I IA+G V RE++F T+KLW V PAL+ SLKKL LDY+DLYL+HFP+A KP
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKP 124
Query: 424 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 564
++P D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 125 GETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKY 184
Query: 565 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGA-PPPRSDDPTLTAL 741
+PV NQ+E +P Q L+ C+S I ++A+S G + P +DP L AL
Sbjct: 185 KPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCAL 244
Query: 742 ANKYR 756
A K++
Sbjct: 245 AKKHK 249
>DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 175 bits (425), Expect = 2e-43
Identities = 100/249 (40%), Positives = 145/249 (58%), Gaps = 14/249 (5%)
Frame = +1
Query: 52 KRLVIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQ 231
K ++LNDG+ +P++ GT A + +A AIEAG+RHID+A +Y +EEQ
Sbjct: 4 KHQCVKLNDGHFMPVLGFGT---YAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQ 60
Query: 232 VGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 411
VG + IA+G V RE++F T+KLW + H + V PAL+ SLKK LDY+DLYLIH P+
Sbjct: 61 VGLAVRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKKAQLDYVDLYLIHSPM 120
Query: 412 ATKPDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 558
+ KP + SP D +D TW+ M+ + GLA+SIGVSNFN Q+ +++
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 559 YI--RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFV-VSRGQTGAPPPRSDDPT 729
+ +PV NQ+E +P + L+ C+S I ++AYS G R P +DP
Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240
Query: 730 LTALANKYR 756
L ALA K++
Sbjct: 241 LCALAKKHK 249
>CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 174 bits (424), Expect = 3e-43
Identities = 99/241 (41%), Positives = 140/241 (58%), Gaps = 13/241 (5%)
Frame = +1
Query: 70 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 249
LN+G +PI+ LGT + +V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 7 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 250 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 423
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+PI KP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPIGFKPGK 120
Query: 424 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 570
D+S P + + L+TW M++ GL ++IG+SNFN Q+ +++ + +P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 571 VINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANK 750
+NQIE +P TQE L+ +CQS GI V AYSP G P +DP + A+A K
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 240
Query: 751 Y 753
+
Sbjct: 241 H 241
>BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 174 bits (424), Expect = 3e-43
Identities = 99/245 (40%), Positives = 143/245 (58%), Gaps = 14/245 (5%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
++LNDG+ +P++ GT + EV + AIEAG+RHID+A +Y +EEQVG
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKL---AIEAGFRHIDSAYLYNNEEQVGLA 64
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 423
I IA+G V RE++F T+KLW V PAL+ SLKKL LDY+DLYL+HFP+A KP
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKP 124
Query: 424 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 564
++P D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 125 GETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNYRQLEMILNKPGLKY 184
Query: 565 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGA-PPPRSDDPTLTAL 741
+PV NQ+E +P Q L+ C+S I ++A+S G + P +DP L AL
Sbjct: 185 KPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCAL 244
Query: 742 ANKYR 756
A K++
Sbjct: 245 AKKHK 249
>D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein.
Length = 325
Score = 174 bits (423), Expect = 3e-43
Identities = 101/249 (40%), Positives = 145/249 (58%), Gaps = 14/249 (5%)
Frame = +1
Query: 52 KRLVIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQ 231
K+ ++LNDG+ +P++ GT EV + AIEAG+RHID+A +Y +EEQ
Sbjct: 6 KQQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQ 62
Query: 232 VGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 411
VG I IA+G V RE++F T+KLW+ H + V PAL+ SLKK LDY+DLYLIH P+
Sbjct: 63 VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 122
Query: 412 ATKPDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 558
+ KP + SP D +D TW+ M+ + GLA+SIGVSNFN Q+ +++
Sbjct: 123 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 182
Query: 559 YI--RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFV-VSRGQTGAPPPRSDDPT 729
+ +PV NQ+E +P + L+ C+S I ++AYS G R P +DP
Sbjct: 183 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 242
Query: 730 LTALANKYR 756
L ALA K++
Sbjct: 243 LCALAKKHK 251
>AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthase
protein.
Length = 323
Score = 174 bits (423), Expect = 3e-43
Identities = 101/249 (40%), Positives = 145/249 (58%), Gaps = 14/249 (5%)
Frame = +1
Query: 52 KRLVIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQ 231
K+ ++LNDG+ +P++ GT EV + AIEAG+RHID+A +Y +EEQ
Sbjct: 4 KQQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQ 60
Query: 232 VGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 411
VG I IA+G V RE++F T+KLW+ H + V PAL+ SLKK LDY+DLYLIH P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120
Query: 412 ATKPDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 558
+ KP + SP D +D TW+ M+ + GLA+SIGVSNFN Q+ +++
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 559 YI--RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFV-VSRGQTGAPPPRSDDPT 729
+ +PV NQ+E +P + L+ C+S I ++AYS G R P +DP
Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240
Query: 730 LTALANKYR 756
L ALA K++
Sbjct: 241 LCALAKKHK 249
>AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein.
Length = 323
Score = 174 bits (423), Expect = 3e-43
Identities = 101/249 (40%), Positives = 145/249 (58%), Gaps = 14/249 (5%)
Frame = +1
Query: 52 KRLVIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQ 231
K+ ++LNDG+ +P++ GT EV + AIEAG+RHID+A +Y +EEQ
Sbjct: 4 KQQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQ 60
Query: 232 VGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 411
VG I IA+G V RE++F T+KLW+ H + V PAL+ SLKK LDY+DLYLIH P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120
Query: 412 ATKPDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 558
+ KP + SP D +D TW+ M+ + GLA+SIGVSNFN Q+ +++
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 559 YI--RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFV-VSRGQTGAPPPRSDDPT 729
+ +PV NQ+E +P + L+ C+S I ++AYS G R P +DP
Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240
Query: 730 LTALANKYR 756
L ALA K++
Sbjct: 241 LCALAKKHK 249
>BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 173 bits (422), Expect = 4e-43
Identities = 101/249 (40%), Positives = 144/249 (57%), Gaps = 14/249 (5%)
Frame = +1
Query: 52 KRLVIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQ 231
K ++LNDG+ +P++ GT EV + AIEAG+RHID+A +Y +EEQ
Sbjct: 4 KHQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQ 60
Query: 232 VGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 411
VG I IA+G V RE++F T+KLW+ H + V PAL+ SLKK LDY+DLYLIH P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120
Query: 412 ATKPDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 558
+ KP + SP D +D TW+ M+ + GLA+SIGVSNFN Q+ +++
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 559 YI--RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFV-VSRGQTGAPPPRSDDPT 729
+ +PV NQ+E +P + L+ C+S I ++AYS G R P +DP
Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240
Query: 730 LTALANKYR 756
L ALA K++
Sbjct: 241 LCALAKKHK 249
>BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 173 bits (422), Expect = 4e-43
Identities = 101/249 (40%), Positives = 144/249 (57%), Gaps = 14/249 (5%)
Frame = +1
Query: 52 KRLVIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQ 231
K ++LNDG+ +P++ GT EV + AIEAG+RHID+A +Y +EEQ
Sbjct: 4 KHQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQ 60
Query: 232 VGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 411
VG I IA+G V RE++F T+KLW+ H + V PAL+ SLKK LDY+DLYLIH P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120
Query: 412 ATKPDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 558
+ KP + SP D +D TW+ M+ + GLA+SIGVSNFN Q+ +++
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 559 YI--RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFV-VSRGQTGAPPPRSDDPT 729
+ +PV NQ+E +P + L+ C+S I ++AYS G R P +DP
Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240
Query: 730 LTALANKYR 756
L ALA K++
Sbjct: 241 LCALAKKHK 249
>BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 173 bits (422), Expect = 4e-43
Identities = 101/249 (40%), Positives = 144/249 (57%), Gaps = 14/249 (5%)
Frame = +1
Query: 52 KRLVIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQ 231
K ++LNDG+ +P++ GT EV + AIEAG+RHID+A +Y +EEQ
Sbjct: 4 KHQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQ 60
Query: 232 VGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 411
VG I IA+G V RE++F T+KLW+ H + V PAL+ SLKK LDY+DLYLIH P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120
Query: 412 ATKPDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 558
+ KP + SP D +D TW+ M+ + GLA+SIGVSNFN Q+ +++
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 559 YI--RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFV-VSRGQTGAPPPRSDDPT 729
+ +PV NQ+E +P + L+ C+S I ++AYS G R P +DP
Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240
Query: 730 LTALANKYR 756
L ALA K++
Sbjct: 241 LCALAKKHK 249
>AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 173 bits (422), Expect = 4e-43
Identities = 101/249 (40%), Positives = 144/249 (57%), Gaps = 14/249 (5%)
Frame = +1
Query: 52 KRLVIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQ 231
K ++LNDG+ +P++ GT EV + AIEAG+RHID+A +Y +EEQ
Sbjct: 4 KHQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQ 60
Query: 232 VGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 411
VG I IA+G V RE++F T+KLW+ H + V PAL+ SLKK LDY+DLYLIH P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120
Query: 412 ATKPDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 558
+ KP + SP D +D TW+ M+ + GLA+SIGVSNFN Q+ +++
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 559 YI--RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFV-VSRGQTGAPPPRSDDPT 729
+ +PV NQ+E +P + L+ C+S I ++AYS G R P +DP
Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240
Query: 730 LTALANKYR 756
L ALA K++
Sbjct: 241 LCALAKKHK 249
>S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 173 bits (421), Expect = 6e-43
Identities = 101/249 (40%), Positives = 145/249 (58%), Gaps = 14/249 (5%)
Frame = +1
Query: 52 KRLVIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQ 231
K+ ++LNDG+ +P++ GT EV + AIEAG+RHID+A +Y +EEQ
Sbjct: 4 KQQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQ 60
Query: 232 VGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 411
VG I IA+G V RE++F T+KLW+ H + V PAL+ SLKK LDY+DLYLIH P+
Sbjct: 61 VGLAIRSKIADGSVEREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120
Query: 412 ATKPDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 558
+ KP + SP D +D TW+ M+ + GLA+SIGVSNFN Q+ +++
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKP 180
Query: 559 YI--RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFV-VSRGQTGAPPPRSDDPT 729
+ +PV NQ+E +P + L+ C+S I ++AYS G R P +DP
Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240
Query: 730 LTALANKYR 756
L ALA K++
Sbjct: 241 LCALAKKHK 249
>L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 173 bits (421), Expect = 6e-43
Identities = 101/249 (40%), Positives = 145/249 (58%), Gaps = 14/249 (5%)
Frame = +1
Query: 52 KRLVIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQ 231
K+ ++LNDG+ +P++ GT EV + AIEAG+RHID+A +Y +EEQ
Sbjct: 4 KQQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQ 60
Query: 232 VGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 411
VG I IA+G V RE++F T+KLW+ H + V PAL+ SLKK LDY+DLYLIH P+
Sbjct: 61 VGLAIRSKIADGSVMREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120
Query: 412 ATKPDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 558
+ KP + SP D +D TW+ M+ + GLA+SIGVSNFN Q+ +++
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKP 180
Query: 559 YI--RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFV-VSRGQTGAPPPRSDDPT 729
+ +PV NQ+E +P + L+ C+S I ++AYS G R P +DP
Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240
Query: 730 LTALANKYR 756
L ALA K++
Sbjct: 241 LCALAKKHK 249
>J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 173 bits (421), Expect = 6e-43
Identities = 99/243 (40%), Positives = 140/243 (57%), Gaps = 13/243 (5%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
I LN+G +PI+ LGT + +V +AV AI+ GYRHID A VYQ+E +VG
Sbjct: 5 ILLNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVA 58
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 423
I E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP
Sbjct: 59 IQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKP 118
Query: 424 -------DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 564
D+S P + + L+TW M++ GL ++IG+SNFN Q+ +++ +
Sbjct: 119 GKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKY 178
Query: 565 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALA 744
+P +NQIE +P TQE L+ +CQS GI V AYSP G P +DP + A+A
Sbjct: 179 KPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIA 238
Query: 745 NKY 753
K+
Sbjct: 239 AKH 241
>X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for
aldose reductase (EC 1.1.1.2). ).
Length = 316
Score = 172 bits (419), Expect = 1e-42
Identities = 98/241 (40%), Positives = 139/241 (57%), Gaps = 13/241 (5%)
Frame = +1
Query: 70 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 249
LN+G +PI+ LGT + +V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 7 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 250 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 423
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 424 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 570
D+S P + + L+TW M++ GL ++IG+SNFN Q+ +++ + +P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 571 VINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANK 750
+NQIE +P TQE L+ +CQS GI V AYSP G P +DP + A+A K
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 240
Query: 751 Y 753
+
Sbjct: 241 H 241
>S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase
homolog protein.
Length = 320
Score = 172 bits (419), Expect = 1e-42
Identities = 95/245 (38%), Positives = 141/245 (57%), Gaps = 14/245 (5%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
++LNDG+ +P++ GT A + +A AIEAG+RHID+A +Y +EEQVG
Sbjct: 5 VKLNDGHFMPVLGFGT---YAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLA 61
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 423
I IA+G V RE++F T+KLW + H + PAL+ SLK L LDY+DLYLIHFP++ KP
Sbjct: 62 IRSKIADGSVKREDIFYTSKLWCNSHRPELDRPALERSLKNLQLDYVDLYLIHFPVSVKP 121
Query: 424 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS--YI 564
+ D +D TW+ ++ + LA+SIGVSNFN + + +++ +
Sbjct: 122 GEEVIPKDENGKILFDTVDLCATWEAVEKCKDAELAKSIGVSNFNRSTLEMILNKPGLQV 181
Query: 565 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGA-PPPRSDDPTLTAL 741
+PV NQ+E +P Q L+ C+S I ++AYS G + P +DP L AL
Sbjct: 182 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSLREEPWVDPNSPVLLEDPVLCAL 241
Query: 742 ANKYR 756
A K++
Sbjct: 242 AKKHK 246
>M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 172 bits (419), Expect = 1e-42
Identities = 98/241 (40%), Positives = 139/241 (57%), Gaps = 13/241 (5%)
Frame = +1
Query: 70 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 249
LN+G +PI+ LGT + +V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 7 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 250 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 423
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 424 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 570
D+S P + + L+TW M++ GL ++IG+SNFN Q+ +++ + +P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 571 VINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANK 750
+NQIE +P TQE L+ +CQS GI V AYSP G P +DP + A+A K
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 240
Query: 751 Y 753
+
Sbjct: 241 H 241
>M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose
reductase mRNA, complete cds. ).
Length = 316
Score = 172 bits (419), Expect = 1e-42
Identities = 98/241 (40%), Positives = 139/241 (57%), Gaps = 13/241 (5%)
Frame = +1
Query: 70 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 249
LN+G +PI+ LGT + +V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 7 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 250 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 423
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 424 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 570
D+S P + + L+TW M++ GL ++IG+SNFN Q+ +++ + +P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 571 VINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANK 750
+NQIE +P TQE L+ +CQS GI V AYSP G P +DP + A+A K
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 240
Query: 751 Y 753
+
Sbjct: 241 H 241
>J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 172 bits (419), Expect = 1e-42
Identities = 98/241 (40%), Positives = 139/241 (57%), Gaps = 13/241 (5%)
Frame = +1
Query: 70 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 249
LN+G +PI+ LGT + +V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 7 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 250 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 423
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 424 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 570
D+S P + + L+TW M++ GL ++IG+SNFN Q+ +++ + +P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 571 VINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANK 750
+NQIE +P TQE L+ +CQS GI V AYSP G P +DP + A+A K
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 240
Query: 751 Y 753
+
Sbjct: 241 H 241
>J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 172 bits (419), Expect = 1e-42
Identities = 98/241 (40%), Positives = 139/241 (57%), Gaps = 13/241 (5%)
Frame = +1
Query: 70 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 249
LN+G +PI+ LGT + +V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 7 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 250 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 423
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 424 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 570
D+S P + + L+TW M++ GL ++IG+SNFN Q+ +++ + +P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 571 VINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANK 750
+NQIE +P TQE L+ +CQS GI V AYSP G P +DP + A+A K
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 240
Query: 751 Y 753
+
Sbjct: 241 H 241
>CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 172 bits (419), Expect = 1e-42
Identities = 98/241 (40%), Positives = 139/241 (57%), Gaps = 13/241 (5%)
Frame = +1
Query: 70 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 249
LN+G +PI+ LGT + +V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 7 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 250 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 423
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P +P
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFRPGK 120
Query: 424 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 570
D+S P + + L+TW M++ GL ++IG+SNFN Q+ ++S + +P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILSKPGLKYKP 180
Query: 571 VINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANK 750
+NQIE +P TQE L+ +CQS GI V AYSP G P +DP + A+A K
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 240
Query: 751 Y 753
+
Sbjct: 241 H 241
>BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 172 bits (419), Expect = 1e-42
Identities = 98/241 (40%), Positives = 139/241 (57%), Gaps = 13/241 (5%)
Frame = +1
Query: 70 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 249
LN+G +PI+ LGT + +V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 7 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 250 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 423
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 424 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 570
D+S P + + L+TW M++ GL ++IG+SNFN Q+ +++ + +P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 571 VINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANK 750
+NQIE +P TQE L+ +CQS GI V AYSP G P +DP + A+A K
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 240
Query: 751 Y 753
+
Sbjct: 241 H 241
>BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 172 bits (419), Expect = 1e-42
Identities = 98/241 (40%), Positives = 139/241 (57%), Gaps = 13/241 (5%)
Frame = +1
Query: 70 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 249
LN+G +PI+ LGT + +V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 7 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 250 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 423
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 424 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 570
D+S P + + L+TW M++ GL ++IG+SNFN Q+ +++ + +P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 571 VINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANK 750
+NQIE +P TQE L+ +CQS GI V AYSP G P +DP + A+A K
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 240
Query: 751 Y 753
+
Sbjct: 241 H 241
>BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 172 bits (419), Expect = 1e-42
Identities = 98/241 (40%), Positives = 139/241 (57%), Gaps = 13/241 (5%)
Frame = +1
Query: 70 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 249
LN+G +PI+ LGT + +V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 7 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 250 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 423
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 424 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 570
D+S P + + L+TW M++ GL ++IG+SNFN Q+ +++ + +P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 571 VINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANK 750
+NQIE +P TQE L+ +CQS GI V AYSP G P +DP + A+A K
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 240
Query: 751 Y 753
+
Sbjct: 241 H 241
>AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen
HD-CL-07 protein.
Length = 316
Score = 172 bits (419), Expect = 1e-42
Identities = 98/241 (40%), Positives = 139/241 (57%), Gaps = 13/241 (5%)
Frame = +1
Query: 70 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 249
LN+G +PI+ LGT + +V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 7 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 250 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 423
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 424 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 570
D+S P + + L+TW M++ GL ++IG+SNFN Q+ +++ + +P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 571 VINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANK 750
+NQIE +P TQE L+ +CQS GI V AYSP G P +DP + A+A K
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 240
Query: 751 Y 753
+
Sbjct: 241 H 241
>AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 172 bits (419), Expect = 1e-42
Identities = 98/241 (40%), Positives = 139/241 (57%), Gaps = 13/241 (5%)
Frame = +1
Query: 70 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 249
LN+G +PI+ LGT + +V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 7 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 250 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 423
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 424 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 570
D+S P + + L+TW M++ GL ++IG+SNFN Q+ +++ + +P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 571 VINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANK 750
+NQIE +P TQE L+ +CQS GI V AYSP G P +DP + A+A K
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 240
Query: 751 Y 753
+
Sbjct: 241 H 241
>AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase family
1, member B1 variant protein.
Length = 260
Score = 172 bits (419), Expect = 1e-42
Identities = 98/241 (40%), Positives = 139/241 (57%), Gaps = 13/241 (5%)
Frame = +1
Query: 70 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 249
LN+G +PI+ LGT + +V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 4 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 57
Query: 250 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 423
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP
Sbjct: 58 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 117
Query: 424 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 570
D+S P + + L+TW M++ GL ++IG+SNFN Q+ +++ + +P
Sbjct: 118 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 177
Query: 571 VINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANK 750
+NQIE +P TQE L+ +CQS GI V AYSP G P +DP + A+A K
Sbjct: 178 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 237
Query: 751 Y 753
+
Sbjct: 238 H 238
>D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase
isoform DD1 protein.
Length = 306
Score = 167 bits (406), Expect = 4e-41
Identities = 90/214 (42%), Positives = 127/214 (59%), Gaps = 14/214 (6%)
Frame = +1
Query: 157 QAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQV 336
+A AIEAG+RHID+A +Y +EEQVG I IA+G V RE++F T+KLW + H + V
Sbjct: 19 EATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELV 78
Query: 337 VPALQESLKKLGLDYIDLYLIHFPIATKPDDSP-----------DNIDYLETWQGMQDAR 483
PAL+ SLK L LDY+DLYLIHFP++ KP + D +D TW+ ++ +
Sbjct: 79 RPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCK 138
Query: 484 QLGLARSIGVSNFNATQITRLVSNSYI--RPVINQIEVNPTNTQEPLVAHCQSLGIAVMA 657
GLA+SIGVSNFN Q+ +++ + +PV NQ+E +P Q L+ C+S I ++A
Sbjct: 139 DAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVA 198
Query: 658 YSPFGFVVSRGQTGA-PPPRSDDPTLTALANKYR 756
YS G P +DP L ALA K++
Sbjct: 199 YSALGSHREEPWVDPNSPVLLEDPVLCALAKKHK 232
>BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 167 bits (405), Expect = 5e-41
Identities = 97/241 (40%), Positives = 138/241 (57%), Gaps = 13/241 (5%)
Frame = +1
Query: 70 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 249
LN+G +PI+ LGT + +V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 7 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 250 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 423
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 424 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 570
D+S P + + L+T M++ GL ++IG+SNFN Q+ +++ + +P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTRAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 571 VINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANK 750
+NQIE +P TQE L+ +CQS GI V AYSP G P +DP + A+A K
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 240
Query: 751 Y 753
+
Sbjct: 241 H 241
>M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordecone
reductase mRNA, complete cds. ).
Length = 308
Score = 165 bits (400), Expect = 2e-40
Identities = 90/209 (43%), Positives = 126/209 (60%), Gaps = 14/209 (6%)
Frame = +1
Query: 172 AIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQ 351
AIEAG+RHID+A +Y +EEQVG I IA+G V RE++F T+KLW V PAL+
Sbjct: 26 AIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALE 85
Query: 352 ESLKKLGLDYIDLYLIHFPIATKPDDSP-----------DNIDYLETWQGMQDARQLGLA 498
SLKKL LDY+DLYL+HFP+A KP ++P D +D TW+ M+ + GLA
Sbjct: 86 SSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLA 145
Query: 499 RSIGVSNFNATQITRLVSNSYI--RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFG 672
+SIGVSNFN Q+ +++ + +PV NQ+E +P Q L+ C+S I ++A+S G
Sbjct: 146 KSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG 205
Query: 673 FVVSRGQTGA-PPPRSDDPTLTALANKYR 756
+ P +DP L ALA K++
Sbjct: 206 TQRHKLWVDPNSPVLLEDPVLCALAKKHK 234
>Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5
beta-reductase protein.
Length = 326
Score = 164 bits (399), Expect = 3e-40
Identities = 97/246 (39%), Positives = 137/246 (55%), Gaps = 16/246 (6%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
I L+DGN+IPI+ LGT + +S +V AI+ GYRHID A +YQ+E +VG+
Sbjct: 10 IPLSDGNSIPIIGLGTY--SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEA 67
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 423
I E IA G V RE++F KLW H + V P L+ +L+ L LDY+DLY+I P+A KP
Sbjct: 68 IREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKP 127
Query: 424 DDS----PDNIDYL-------ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 564
D +N +L TW+ M+ + GL +S+GVSNFN Q+ +++ +
Sbjct: 128 GDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKH 187
Query: 565 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQ---TGAPPPRSDDPTLT 735
+PV NQ+E +P TQ L+ CQ I + AYSP G SR + PP D L
Sbjct: 188 KPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLG--TSRNPIWVNVSSPPLLKDALLN 245
Query: 736 ALANKY 753
+L +Y
Sbjct: 246 SLGKRY 251
>BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 164 bits (399), Expect = 3e-40
Identities = 97/246 (39%), Positives = 137/246 (55%), Gaps = 16/246 (6%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
I L+DGN+IPI+ LGT + +S +V AI+ GYRHID A +YQ+E +VG+
Sbjct: 10 IPLSDGNSIPIIGLGTY--SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEA 67
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 423
I E IA G V RE++F KLW H + V P L+ +L+ L LDY+DLY+I P+A KP
Sbjct: 68 IREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKP 127
Query: 424 DDS----PDNIDYL-------ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 564
D +N +L TW+ M+ + GL +S+GVSNFN Q+ +++ +
Sbjct: 128 GDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKH 187
Query: 565 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQ---TGAPPPRSDDPTLT 735
+PV NQ+E +P TQ L+ CQ I + AYSP G SR + PP D L
Sbjct: 188 KPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLG--TSRNPIWVNVSSPPLLKDALLN 245
Query: 736 ALANKY 753
+L +Y
Sbjct: 246 SLGKRY 251
>BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 164 bits (399), Expect = 3e-40
Identities = 97/246 (39%), Positives = 137/246 (55%), Gaps = 16/246 (6%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
I L+DGN+IPI+ LGT + +S +V AI+ GYRHID A +YQ+E +VG+
Sbjct: 10 IPLSDGNSIPIIGLGTY--SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEA 67
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 423
I E IA G V RE++F KLW H + V P L+ +L+ L LDY+DLY+I P+A KP
Sbjct: 68 IREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKP 127
Query: 424 DDS----PDNIDYL-------ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 564
D +N +L TW+ M+ + GL +S+GVSNFN Q+ +++ +
Sbjct: 128 GDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKH 187
Query: 565 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQ---TGAPPPRSDDPTLT 735
+PV NQ+E +P TQ L+ CQ I + AYSP G SR + PP D L
Sbjct: 188 KPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLG--TSRNPIWVNVSSPPLLKDALLN 245
Query: 736 ALANKY 753
+L +Y
Sbjct: 246 SLGKRY 251
>AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductase
protein.
Length = 326
Score = 164 bits (399), Expect = 3e-40
Identities = 97/246 (39%), Positives = 137/246 (55%), Gaps = 16/246 (6%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
I L+DGN+IPI+ LGT + +S +V AI+ GYRHID A +YQ+E +VG+
Sbjct: 10 IPLSDGNSIPIIGLGTY--SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEA 67
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 423
I E IA G V RE++F KLW H + V P L+ +L+ L LDY+DLY+I P+A KP
Sbjct: 68 IREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKP 127
Query: 424 DDS----PDNIDYL-------ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 564
D +N +L TW+ M+ + GL +S+GVSNFN Q+ +++ +
Sbjct: 128 GDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKH 187
Query: 565 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQ---TGAPPPRSDDPTLT 735
+PV NQ+E +P TQ L+ CQ I + AYSP G SR + PP D L
Sbjct: 188 KPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLG--TSRNPIWVNVSSPPLLKDALLN 245
Query: 736 ALANKY 753
+L +Y
Sbjct: 246 SLGKRY 251
>U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like
peptide protein.
Length = 316
Score = 159 bits (387), Expect = 8e-39
Identities = 93/244 (38%), Positives = 138/244 (56%), Gaps = 13/244 (5%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
++L+ +PIV LGT + + +V++AV AI+AGYRHID A VYQ+E +VG+
Sbjct: 5 VELSTKAKMPIVGLGTWKSP------LGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEA 58
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK- 420
I E I V RE+LF+ +KLW R V A +++LK L L Y+D+YLIH+P K
Sbjct: 59 IQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKS 118
Query: 421 -----PDDSPDN-----IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 564
P D N +L+ W+ M++ GL +++GVSNF+ QI +L++ +
Sbjct: 119 GDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKY 178
Query: 565 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALA 744
+PV NQ+E +P TQE L+ +C S GI V AYSP G P +DP + +A
Sbjct: 179 KPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIA 238
Query: 745 NKYR 756
K++
Sbjct: 239 AKHK 242
>CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein.
Length = 316
Score = 159 bits (387), Expect = 8e-39
Identities = 93/244 (38%), Positives = 138/244 (56%), Gaps = 13/244 (5%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
++L+ +PIV LGT + + +V++AV AI+AGYRHID A VYQ+E +VG+
Sbjct: 5 VELSTKAKMPIVGLGTWKSP------LGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEA 58
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK- 420
I E I V RE+LF+ +KLW R V A +++LK L L Y+D+YLIH+P K
Sbjct: 59 IQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKS 118
Query: 421 -----PDDSPDN-----IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 564
P D N +L+ W+ M++ GL +++GVSNF+ QI +L++ +
Sbjct: 119 GDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKY 178
Query: 565 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALA 744
+PV NQ+E +P TQE L+ +C S GI V AYSP G P +DP + +A
Sbjct: 179 KPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIA 238
Query: 745 NKYR 756
K++
Sbjct: 239 AKHK 242
>BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 159 bits (387), Expect = 8e-39
Identities = 93/244 (38%), Positives = 138/244 (56%), Gaps = 13/244 (5%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
++L+ +PIV LGT + + +V++AV AI+AGYRHID A VYQ+E +VG+
Sbjct: 5 VELSTKAKMPIVGLGTWKSP------LGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEA 58
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK- 420
I E I V RE+LF+ +KLW R V A +++LK L L Y+D+YLIH+P K
Sbjct: 59 IQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKS 118
Query: 421 -----PDDSPDN-----IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 564
P D N +L+ W+ M++ GL +++GVSNF+ QI +L++ +
Sbjct: 119 GDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKY 178
Query: 565 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALA 744
+PV NQ+E +P TQE L+ +C S GI V AYSP G P +DP + +A
Sbjct: 179 KPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIA 238
Query: 745 NKYR 756
K++
Sbjct: 239 AKHK 242
>BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 159 bits (387), Expect = 8e-39
Identities = 93/244 (38%), Positives = 138/244 (56%), Gaps = 13/244 (5%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
++L+ +PIV LGT + + +V++AV AI+AGYRHID A VYQ+E +VG+
Sbjct: 5 VELSTKAKMPIVGLGTWKSP------LGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEA 58
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK- 420
I E I V RE+LF+ +KLW R V A +++LK L L Y+D+YLIH+P K
Sbjct: 59 IQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKS 118
Query: 421 -----PDDSPDN-----IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 564
P D N +L+ W+ M++ GL +++GVSNF+ QI +L++ +
Sbjct: 119 GDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKY 178
Query: 565 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALA 744
+PV NQ+E +P TQE L+ +C S GI V AYSP G P +DP + +A
Sbjct: 179 KPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIA 238
Query: 745 NKYR 756
K++
Sbjct: 239 AKHK 242
>AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase
protein.
Length = 316
Score = 159 bits (387), Expect = 8e-39
Identities = 93/244 (38%), Positives = 138/244 (56%), Gaps = 13/244 (5%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
++L+ +PIV LGT + + +V++AV AI+AGYRHID A VYQ+E +VG+
Sbjct: 5 VELSTKAKMPIVGLGTWKSP------LGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEA 58
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK- 420
I E I V RE+LF+ +KLW R V A +++LK L L Y+D+YLIH+P K
Sbjct: 59 IQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKS 118
Query: 421 -----PDDSPDN-----IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 564
P D N +L+ W+ M++ GL +++GVSNF+ QI +L++ +
Sbjct: 119 GDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKY 178
Query: 565 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALA 744
+PV NQ+E +P TQE L+ +C S GI V AYSP G P +DP + +A
Sbjct: 179 KPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIA 238
Query: 745 NKYR 756
K++
Sbjct: 239 AKHK 242
>AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase
protein.
Length = 316
Score = 157 bits (380), Expect = 5e-38
Identities = 92/244 (37%), Positives = 137/244 (56%), Gaps = 13/244 (5%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
++L+ +PIV LGT + + +V++AV AI+AGYRHID A VYQ+E +VG+
Sbjct: 5 VELSTKAKMPIVGLGTWKSP------LGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEA 58
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK- 420
I E I V RE+LF+ +KLW R V A +++LK L Y+D+YLIH+P K
Sbjct: 59 IQEKIQEKAVKREDLFIASKLWPTFFERPLVRKAFEKTLKDPKLSYLDVYLIHWPQGFKS 118
Query: 421 -----PDDSPDN-----IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 564
P D N +L+ W+ M++ GL +++GVSNF+ QI +L++ +
Sbjct: 119 GDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKY 178
Query: 565 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALA 744
+PV NQ+E +P TQE L+ +C S GI V AYSP G P +DP + +A
Sbjct: 179 KPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIA 238
Query: 745 NKYR 756
K++
Sbjct: 239 AKHK 242
>AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 247
Score = 136 bits (330), Expect = 6e-32
Identities = 75/190 (39%), Positives = 108/190 (56%), Gaps = 14/190 (7%)
Frame = +1
Query: 229 QVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP 408
+VG I IA+G V RE++F T+KLW + H + V PAL+ SLK L LDY+DLYLIHFP
Sbjct: 26 EVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 85
Query: 409 IATKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSN 555
++ KP + D +D TW+ ++ + GLA+SIGVSNFN Q+ +++
Sbjct: 86 VSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNK 145
Query: 556 SYI--RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGA-PPPRSDDP 726
+ +PV NQ+E +P Q L+ C+S I ++AYS G P +DP
Sbjct: 146 PGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDP 205
Query: 727 TLTALANKYR 756
L ALA K++
Sbjct: 206 VLCALAKKHK 215
>AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 123 bits (296), Expect = 8e-28
Identities = 81/237 (34%), Positives = 123/237 (51%), Gaps = 2/237 (0%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
++LNDG +P++ GT A + + +A AI+ G+RHID+A +YQ+EE+VGQ
Sbjct: 11 VRLNDGPFMPVLGFGT---YAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQA 67
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 423
I E IA+G V REE+F T KLW + V PAL+ SLKKLG DY+DL++IH P A K
Sbjct: 68 IWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMKQ 127
Query: 424 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQ-IEVNPT 600
+ L +DA + ++ + + ++ +P NQ +E +P
Sbjct: 128 PGK----ELLP-----KDASGEIILETVELCDTWELELILNKPGLRYKPTCNQVVECHPY 178
Query: 601 NTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPR-SDDPTLTALANKYRXSVG 768
Q L+ C+S I ++AYS G P ++P L ++A K+ S G
Sbjct: 179 LNQSKLLEFCKSKDIVLVAYSALGSQRDPQWVDPDCPHLLEEPILKSIAKKHSRSPG 235
>AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 123 bits (296), Expect = 8e-28
Identities = 81/237 (34%), Positives = 123/237 (51%), Gaps = 2/237 (0%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
++LNDG +P++ GT A + + +A AI+ G+RHID+A +YQ+EE+VGQ
Sbjct: 11 VRLNDGPFMPVLGFGT---YAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQA 67
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 423
I E IA+G V REE+F T KLW + V PAL+ SLKKLG DY+DL++IH P A K
Sbjct: 68 IWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMKQ 127
Query: 424 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQ-IEVNPT 600
+ L +DA + ++ + + ++ +P NQ +E +P
Sbjct: 128 PGK----ELLP-----KDASGEIILETVELCDTWELELILNKPGLRYKPTCNQVVECHPY 178
Query: 601 NTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPR-SDDPTLTALANKYRXSVG 768
Q L+ C+S I ++AYS G P ++P L ++A K+ S G
Sbjct: 179 LNQSKLLEFCKSKDIVLVAYSALGSQRDPQWVDPDCPHLLEEPILKSIAKKHSRSPG 235
>BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein.
Length = 307
Score = 115 bits (276), Expect = 2e-25
Identities = 80/217 (36%), Positives = 113/217 (52%), Gaps = 32/217 (14%)
Frame = +1
Query: 118 GTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVT 297
G + S +V +AV AI+AGYRH D A Y +E +VG GI I G V RE+LF+
Sbjct: 8 GLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIA 67
Query: 298 TKLWNDKHARDQVVPALQ---ESLKKLGLDY----------------------IDLYLIH 402
TKLW H + V A + ++LK LD + L H
Sbjct: 68 TKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSH 127
Query: 403 FPIATKP-DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR 567
+ P D+S P + D+L+TW+ M+D GL ++IGVSNFN Q+ RL++ +R
Sbjct: 128 PRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLR 187
Query: 568 --PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFG 672
P+ NQIE +P TQ+ L++ CQS ++V AY P G
Sbjct: 188 FKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLG 224
>AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase
loopADR protein.
Length = 320
Score = 115 bits (276), Expect = 2e-25
Identities = 80/217 (36%), Positives = 113/217 (52%), Gaps = 32/217 (14%)
Frame = +1
Query: 118 GTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVT 297
G + S +V +AV AI+AGYRH D A Y +E +VG GI I G V RE+LF+
Sbjct: 8 GLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIA 67
Query: 298 TKLWNDKHARDQVVPALQ---ESLKKLGLDY----------------------IDLYLIH 402
TKLW H + V A + ++LK LD + L H
Sbjct: 68 TKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSH 127
Query: 403 FPIATKP-DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR 567
+ P D+S P + D+L+TW+ M+D GL ++IGVSNFN Q+ RL++ +R
Sbjct: 128 PRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLR 187
Query: 568 --PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFG 672
P+ NQIE +P TQ+ L++ CQS ++V AY P G
Sbjct: 188 FKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLG 224
>AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase
related protein 4 protein.
Length = 307
Score = 115 bits (276), Expect = 2e-25
Identities = 80/217 (36%), Positives = 113/217 (52%), Gaps = 32/217 (14%)
Frame = +1
Query: 118 GTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVT 297
G + S +V +AV AI+AGYRH D A Y +E +VG GI I G V RE+LF+
Sbjct: 8 GLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIA 67
Query: 298 TKLWNDKHARDQVVPALQ---ESLKKLGLDY----------------------IDLYLIH 402
TKLW H + V A + ++LK LD + L H
Sbjct: 68 TKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSH 127
Query: 403 FPIATKP-DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR 567
+ P D+S P + D+L+TW+ M+D GL ++IGVSNFN Q+ RL++ +R
Sbjct: 128 PRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLR 187
Query: 568 --PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFG 672
P+ NQIE +P TQ+ L++ CQS ++V AY P G
Sbjct: 188 FKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLG 224
>BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 114 bits (274), Expect = 4e-25
Identities = 57/119 (47%), Positives = 78/119 (65%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
++LNDG +P++ GT A + + +A AI+ G+RHID+A +YQ+EE+VGQ
Sbjct: 11 VRLNDGPFMPVLGFGT---YAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQA 67
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 420
I E IA+G V REE+F T KLW + V PAL+ SLKKLG DY+DL++IH P A K
Sbjct: 68 IWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMK 126
>BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 114 bits (274), Expect = 4e-25
Identities = 57/119 (47%), Positives = 78/119 (65%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
++LNDG +P++ GT A + + +A AI+ G+RHID+A +YQ+EE+VGQ
Sbjct: 11 VRLNDGPFMPVLGFGT---YAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQA 67
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 420
I E IA+G V REE+F T KLW + V PAL+ SLKKLG DY+DL++IH P A K
Sbjct: 68 IWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMK 126
>AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens
cDNA FLJ16347 fis, clone TESTI2036288, moderately
similar to PROSTAGLANDIN-F SYNTHASE 1 (EC 1.1.1.188). ).
Length = 129
Score = 114 bits (274), Expect = 4e-25
Identities = 57/119 (47%), Positives = 78/119 (65%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
++LNDG +P++ GT A + + +A AI+ G+RHID+A +YQ+EE+VGQ
Sbjct: 11 VRLNDGPFMPVLGFGT---YAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQA 67
Query: 244 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 420
I E IA+G V REE+F T KLW + V PAL+ SLKKLG DY+DL++IH P A K
Sbjct: 68 IWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMK 126
>AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydela) protein.
Length = 147
Score = 112 bits (270), Expect = 1e-24
Identities = 59/148 (39%), Positives = 90/148 (60%), Gaps = 12/148 (8%)
Frame = +1
Query: 64 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 243
+ L+ G +P++ LGT + +V+ AV +A+ GYRHID AA+Y +E ++G+
Sbjct: 6 VLLHTGQKMPLIGLGTWKSEP------GQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEA 59
Query: 244 IAEAIANG-LVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 420
+ E + G V REELFVT+KLWN KH + V PAL+++L L L+Y+DLYL+H+P A +
Sbjct: 60 LKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFE 119
Query: 421 PDDSP-----------DNIDYLETWQGM 471
D+P D+ Y ETW+ +
Sbjct: 120 RGDNPFPKNADGTICYDSTHYKETWKAL 147
>AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto
reductase protein.
Length = 130
Score = 109 bits (263), Expect = 8e-24
Identities = 55/125 (44%), Positives = 78/125 (62%)
Frame = +1
Query: 58 LVIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 237
L ++LNDG +PI+ GT + ++ V +AV AI+ GYRHID+A + +EE +G
Sbjct: 7 LSVKLNDGKFMPILGFGT---SVARKVAMSNVEEAVQVAIDVGYRHIDSAYTHLNEEGIG 63
Query: 238 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 417
Q I + IANG V R+++F TTK+W + V L+ SLKKL L Y+DLYL HFP+
Sbjct: 64 QAIRKKIANGTVKRKDIFYTTKVWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPVPL 123
Query: 418 KPDDS 432
+P S
Sbjct: 124 QPGRS 128
>AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase
related protein 3 protein.
Length = 222
Score = 97.1 bits (231), Expect = 6e-20
Identities = 49/102 (48%), Positives = 64/102 (62%)
Frame = +1
Query: 118 GTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVT 297
G + S +V +AV AI+AGYRH D A Y +E +VG GI I G V RE+LF+
Sbjct: 8 GLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIA 67
Query: 298 TKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 423
TKLW H + V A ++SLK L L+Y+DLYLIH+P+ KP
Sbjct: 68 TKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKP 109
>AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase
related protein 2 protein.
Length = 263
Score = 97.1 bits (231), Expect = 6e-20
Identities = 49/102 (48%), Positives = 64/102 (62%)
Frame = +1
Query: 118 GTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVT 297
G + S +V +AV AI+AGYRH D A Y +E +VG GI I G V RE+LF+
Sbjct: 8 GLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIA 67
Query: 298 TKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 423
TKLW H + V A ++SLK L L+Y+DLYLIH+P+ KP
Sbjct: 68 TKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKP 109
>AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase
related protein 1 protein.
Length = 250
Score = 97.1 bits (231), Expect = 6e-20
Identities = 49/102 (48%), Positives = 64/102 (62%)
Frame = +1
Query: 118 GTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVT 297
G + S +V +AV AI+AGYRH D A Y +E +VG GI I G V RE+LF+
Sbjct: 8 GLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIA 67
Query: 298 TKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 423
TKLW H + V A ++SLK L L+Y+DLYLIH+P+ KP
Sbjct: 68 TKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKP 109
>AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens
cDNA FLJ25413 fis, clone TST03402, highly similar to
3-OXO-5-BETA-STEROID 4-DEHYDROGENASE (EC 1.3.99.6). ).
Length = 146
Score = 65.3 bits (152), Expect = 2e-10
Identities = 30/74 (40%), Positives = 45/74 (60%), Gaps = 2/74 (2%)
Frame = +1
Query: 457 TWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLVAHC 630
TW+ M+ + GL +S+GVSNFN Q+ +++ ++ PV NQ+E +P TQ L+ C
Sbjct: 28 TWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFC 87
Query: 631 QSLGIAVMAYSPFG 672
Q I + AYSP G
Sbjct: 88 QQHDIVITAYSPLG 101
>Y16675-1|CAA76347.1| 330|Homo sapiens aflatoxin B1-aldehyde
reductase protein.
Length = 330
Score = 53.2 bits (122), Expect = 1e-06
Identities = 49/178 (27%), Positives = 79/178 (44%), Gaps = 9/178 (5%)
Frame = +1
Query: 160 AVYWAIEAGYRHIDTAAVYQD--EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHAR-D 330
AV +E G+ +DTA +Y D E + G+ + G R ++ W+ K + D
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGG-DCRVKIATKANPWDGKSLKPD 88
Query: 331 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 510
V L+ SLK+L +DL+ +H P P + ET Q Q G +G
Sbjct: 89 SVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVE--------ETLHACQRLHQEGKFVELG 140
Query: 511 VSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ-EPLVAHC-QSLGIAVMAYSP 666
+SN+ + ++ + SN +I P + Q N T Q E + C + G+ AY+P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNP 198
>BT007347-1|AAP36011.1| 330|Homo sapiens aldo-keto reductase family
7, member A2 (aflatoxin aldehyde reductase) protein.
Length = 330
Score = 53.2 bits (122), Expect = 1e-06
Identities = 49/178 (27%), Positives = 79/178 (44%), Gaps = 9/178 (5%)
Frame = +1
Query: 160 AVYWAIEAGYRHIDTAAVYQD--EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHAR-D 330
AV +E G+ +DTA +Y D E + G+ + G R ++ W+ K + D
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGG-DCRVKIATKANPWDGKSLKPD 88
Query: 331 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 510
V L+ SLK+L +DL+ +H P P + ET Q Q G +G
Sbjct: 89 SVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVE--------ETLHACQRLHQEGKFVELG 140
Query: 511 VSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ-EPLVAHC-QSLGIAVMAYSP 666
+SN+ + ++ + SN +I P + Q N T Q E + C + G+ AY+P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNP 198
>BC013996-1|AAH13996.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 53.2 bits (122), Expect = 1e-06
Identities = 49/178 (27%), Positives = 79/178 (44%), Gaps = 9/178 (5%)
Frame = +1
Query: 160 AVYWAIEAGYRHIDTAAVYQD--EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHAR-D 330
AV +E G+ +DTA +Y D E + G+ + G R ++ W+ K + D
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGG-DCRVKIATKANPWDGKSLKPD 88
Query: 331 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 510
V L+ SLK+L +DL+ +H P P + ET Q Q G +G
Sbjct: 89 SVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVE--------ETLHACQRLHQEGKFVELG 140
Query: 511 VSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ-EPLVAHC-QSLGIAVMAYSP 666
+SN+ + ++ + SN +I P + Q N T Q E + C + G+ AY+P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNP 198
>BC012171-1|AAH12171.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 53.2 bits (122), Expect = 1e-06
Identities = 49/178 (27%), Positives = 79/178 (44%), Gaps = 9/178 (5%)
Frame = +1
Query: 160 AVYWAIEAGYRHIDTAAVYQD--EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHAR-D 330
AV +E G+ +DTA +Y D E + G+ + G R ++ W+ K + D
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGG-DCRVKIATKANPWDGKSLKPD 88
Query: 331 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 510
V L+ SLK+L +DL+ +H P P + ET Q Q G +G
Sbjct: 89 SVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVE--------ETLHACQRLHQEGKFVELG 140
Query: 511 VSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ-EPLVAHC-QSLGIAVMAYSP 666
+SN+ + ++ + SN +I P + Q N T Q E + C + G+ AY+P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNP 198
>BC011586-1|AAH11586.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 53.2 bits (122), Expect = 1e-06
Identities = 49/178 (27%), Positives = 79/178 (44%), Gaps = 9/178 (5%)
Frame = +1
Query: 160 AVYWAIEAGYRHIDTAAVYQD--EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHAR-D 330
AV +E G+ +DTA +Y D E + G+ + G R ++ W+ K + D
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGG-DCRVKIATKANPWDGKSLKPD 88
Query: 331 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 510
V L+ SLK+L +DL+ +H P P + ET Q Q G +G
Sbjct: 89 SVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVE--------ETLHACQRLHQEGKFVELG 140
Query: 511 VSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ-EPLVAHC-QSLGIAVMAYSP 666
+SN+ + ++ + SN +I P + Q N T Q E + C + G+ AY+P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNP 198
>BC010852-1|AAH10852.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 53.2 bits (122), Expect = 1e-06
Identities = 49/178 (27%), Positives = 79/178 (44%), Gaps = 9/178 (5%)
Frame = +1
Query: 160 AVYWAIEAGYRHIDTAAVYQD--EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHAR-D 330
AV +E G+ +DTA +Y D E + G+ + G R ++ W+ K + D
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGG-DCRVKIATKANPWDGKSLKPD 88
Query: 331 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 510
V L+ SLK+L +DL+ +H P P + ET Q Q G +G
Sbjct: 89 SVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVE--------ETLHACQRLHQEGKFVELG 140
Query: 511 VSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ-EPLVAHC-QSLGIAVMAYSP 666
+SN+ + ++ + SN +I P + Q N T Q E + C + G+ AY+P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNP 198
>BC007352-1|AAH07352.2| 358|Homo sapiens AKR7A2 protein protein.
Length = 358
Score = 53.2 bits (122), Expect = 1e-06
Identities = 49/178 (27%), Positives = 79/178 (44%), Gaps = 9/178 (5%)
Frame = +1
Query: 160 AVYWAIEAGYRHIDTAAVYQD--EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHAR-D 330
AV +E G+ +DTA +Y D E + G+ + G R ++ W+ K + D
Sbjct: 58 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGG-DCRVKIATKANPWDGKSLKPD 116
Query: 331 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 510
V L+ SLK+L +DL+ +H P P + ET Q Q G +G
Sbjct: 117 SVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVE--------ETLHACQRLHQEGKFVELG 168
Query: 511 VSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ-EPLVAHC-QSLGIAVMAYSP 666
+SN+ + ++ + SN +I P + Q N T Q E + C + G+ AY+P
Sbjct: 169 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNP 226
>BC004111-1|AAH04111.3| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 53.2 bits (122), Expect = 1e-06
Identities = 49/178 (27%), Positives = 79/178 (44%), Gaps = 9/178 (5%)
Frame = +1
Query: 160 AVYWAIEAGYRHIDTAAVYQD--EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHAR-D 330
AV +E G+ +DTA +Y D E + G+ + G R ++ W+ K + D
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGG-DCRVKIATKANPWDGKSLKPD 88
Query: 331 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 510
V L+ SLK+L +DL+ +H P P + ET Q Q G +G
Sbjct: 89 SVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVE--------ETLHACQRLHQEGKFVELG 140
Query: 511 VSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ-EPLVAHC-QSLGIAVMAYSP 666
+SN+ + ++ + SN +I P + Q N T Q E + C + G+ AY+P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNP 198
>AL035413-8|CAB72321.1| 330|Homo sapiens aldo-keto reductase family
7, member A2 (aflatoxin aldehyde reductase) protein.
Length = 330
Score = 53.2 bits (122), Expect = 1e-06
Identities = 49/178 (27%), Positives = 79/178 (44%), Gaps = 9/178 (5%)
Frame = +1
Query: 160 AVYWAIEAGYRHIDTAAVYQD--EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHAR-D 330
AV +E G+ +DTA +Y D E + G+ + G R ++ W+ K + D
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGG-DCRVKIATKANPWDGKSLKPD 88
Query: 331 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 510
V L+ SLK+L +DL+ +H P P + ET Q Q G +G
Sbjct: 89 SVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVE--------ETLHACQRLHQEGKFVELG 140
Query: 511 VSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ-EPLVAHC-QSLGIAVMAYSP 666
+SN+ + ++ + SN +I P + Q N T Q E + C + G+ AY+P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNP 198
>AF026947-1|AAC52104.1| 330|Homo sapiens aflatoxin aldehyde
reductase AFAR protein.
Length = 330
Score = 53.2 bits (122), Expect = 1e-06
Identities = 49/178 (27%), Positives = 79/178 (44%), Gaps = 9/178 (5%)
Frame = +1
Query: 160 AVYWAIEAGYRHIDTAAVYQD--EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHAR-D 330
AV +E G+ +DTA +Y D E + G+ + G R ++ W+ K + D
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGG-DCRVKIATKANPWDGKSLKPD 88
Query: 331 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 510
V L+ SLK+L +DL+ +H P P + ET Q Q G +G
Sbjct: 89 SVRSQLETSLKRLQCPQVDLFYLHTPDHGTPVE--------ETLHACQRLHQEGKFVELG 140
Query: 511 VSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ-EPLVAHC-QSLGIAVMAYSP 666
+SN+ + ++ + SN +I P + Q N T Q E + C + G+ AY+P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNP 198
>AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthase
protein.
Length = 67
Score = 46.4 bits (105), Expect = 1e-04
Identities = 21/51 (41%), Positives = 32/51 (62%), Gaps = 2/51 (3%)
Frame = +1
Query: 436 DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RPVINQ 582
D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ + +PV NQ
Sbjct: 17 DIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQ 67
>AF040639-1|AAD02195.1| 331|Homo sapiens aflatoxin B1-aldehyde
reductase protein.
Length = 331
Score = 44.8 bits (101), Expect = 3e-04
Identities = 49/178 (27%), Positives = 78/178 (43%), Gaps = 14/178 (7%)
Frame = +1
Query: 175 IEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTRE-----ELFVTTK---LWNDKHARD 330
+E G+ IDTA VY D G +E I GL R + + TK L+ + D
Sbjct: 36 LERGHTEIDTAFVYSD------GQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPD 89
Query: 331 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 510
+ L+ SLK+L +DL+ +H P + P + ET + Q G +G
Sbjct: 90 SLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVE--------ETLRACHQLHQEGKFMELG 141
Query: 511 VSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ-EPLVAHC-QSLGIAVMAYSP 666
+SN+ A ++ + SN +I P + Q N Q E + C + G+ A++P
Sbjct: 142 LSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNP 199
>BC042420-1|AAH42420.2| 331|Homo sapiens aldo-keto reductase family
7, member A3 (aflatoxin aldehyde reductase) protein.
Length = 331
Score = 43.2 bits (97), Expect = 0.001
Identities = 48/178 (26%), Positives = 78/178 (43%), Gaps = 14/178 (7%)
Frame = +1
Query: 175 IEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTRE-----ELFVTTK---LWNDKHARD 330
+E G+ IDTA VY + G +E I GL R + + TK L+ + D
Sbjct: 36 LERGHTEIDTAFVYSE------GQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPD 89
Query: 331 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 510
+ L+ SLK+L +DL+ +H P + P + ET + Q G +G
Sbjct: 90 SLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVE--------ETLRACHQLHQEGKFMELG 141
Query: 511 VSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ-EPLVAHC-QSLGIAVMAYSP 666
+SN+ A ++ + SN +I P + Q N Q E + C + G+ A++P
Sbjct: 142 LSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNP 199
>BC031562-1|AAH31562.1| 331|Homo sapiens aldo-keto reductase family
7, member A3 (aflatoxin aldehyde reductase) protein.
Length = 331
Score = 43.2 bits (97), Expect = 0.001
Identities = 48/178 (26%), Positives = 78/178 (43%), Gaps = 14/178 (7%)
Frame = +1
Query: 175 IEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTRE-----ELFVTTK---LWNDKHARD 330
+E G+ IDTA VY + G +E I GL R + + TK L+ + D
Sbjct: 36 LERGHTEIDTAFVYSE------GQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPD 89
Query: 331 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 510
+ L+ SLK+L +DL+ +H P + P + ET + Q G +G
Sbjct: 90 SLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVE--------ETLRACHQLHQEGKFMELG 141
Query: 511 VSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ-EPLVAHC-QSLGIAVMAYSP 666
+SN+ A ++ + SN +I P + Q N Q E + C + G+ A++P
Sbjct: 142 LSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNP 199
>AJ271799-1|CAC81076.1| 331|Homo sapiens aflatoxin B1 aldehyde
reductase 2 protein.
Length = 331
Score = 43.2 bits (97), Expect = 0.001
Identities = 48/178 (26%), Positives = 78/178 (43%), Gaps = 14/178 (7%)
Frame = +1
Query: 175 IEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTRE-----ELFVTTK---LWNDKHARD 330
+E G+ IDTA VY + G +E I GL R + + TK L+ + D
Sbjct: 36 LERGHTEIDTAFVYSE------GQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPD 89
Query: 331 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 510
+ L+ SLK+L +DL+ +H P + P + ET + Q G +G
Sbjct: 90 SLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVE--------ETLRACHQLHQEGKFMELG 141
Query: 511 VSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ-EPLVAHC-QSLGIAVMAYSP 666
+SN+ A ++ + SN +I P + Q N Q E + C + G+ A++P
Sbjct: 142 LSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNP 199
>BC025709-1|AAH25709.1| 331|Homo sapiens aldo-keto reductase family
7, member A3 (aflatoxin aldehyde reductase) protein.
Length = 331
Score = 42.3 bits (95), Expect = 0.002
Identities = 48/178 (26%), Positives = 78/178 (43%), Gaps = 14/178 (7%)
Frame = +1
Query: 175 IEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTRE-----ELFVTTK---LWNDKHARD 330
+E G+ IDTA VY + G +E I GL R + + TK L+ + D
Sbjct: 36 LERGHTEIDTAFVYSE------GQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPD 89
Query: 331 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 510
+ L+ SLK+L +DL+ +H P + P + ET + Q G +G
Sbjct: 90 SLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVE--------ETLRACHQLHQEGKFVELG 141
Query: 511 VSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ-EPLVAHC-QSLGIAVMAYSP 666
+SN+ A ++ + SN +I P + Q N Q E + C + G+ A++P
Sbjct: 142 LSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNP 199
>AL035413-11|CAI22232.1| 331|Homo sapiens aldo-keto reductase
family 7, member A3 (aflatoxin aldehyde reductase)
protein.
Length = 331
Score = 42.3 bits (95), Expect = 0.002
Identities = 48/178 (26%), Positives = 78/178 (43%), Gaps = 14/178 (7%)
Frame = +1
Query: 175 IEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTRE-----ELFVTTK---LWNDKHARD 330
+E G+ IDTA VY + G +E I GL R + + TK L+ + D
Sbjct: 36 LERGHTEIDTAFVYSE------GQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPD 89
Query: 331 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 510
+ L+ SLK+L +DL+ +H P + P + ET + Q G +G
Sbjct: 90 SLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVE--------ETLRACHQLHQEGKFVELG 141
Query: 511 VSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ-EPLVAHC-QSLGIAVMAYSP 666
+SN+ A ++ + SN +I P + Q N Q E + C + G+ A++P
Sbjct: 142 LSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNP 199
>AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto
reductase protein.
Length = 45
Score = 41.1 bits (92), Expect = 0.004
Identities = 19/43 (44%), Positives = 25/43 (58%)
Frame = +1
Query: 304 LWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDS 432
+W + V L+ SLKKL L Y+DLYL HFP+ +P S
Sbjct: 1 VWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPVPLQPGRS 43
>AJ278012-1|CAC79668.1| 259|Homo sapiens aflatoxin B1 aldehyde
reductase 3 protein.
Length = 259
Score = 40.3 bits (90), Expect = 0.007
Identities = 32/119 (26%), Positives = 53/119 (44%), Gaps = 6/119 (5%)
Frame = +1
Query: 328 DQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSI 507
D V L+ SLK+L +DL+ +H P + P + ET + Q G +
Sbjct: 17 DSVRSQLETSLKRLQCPUVDLFYLHAPDHSAPVE--------ETLRACHQLHQEGKFVEL 68
Query: 508 GVSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ--EPLVAHCQSLGIAVMAYSP 666
G+SN+ A ++ + SN +I P + Q + T Q L + + G+ AY+P
Sbjct: 69 GLSNYAAWEVAEICTLCKSNGWILPTVYQGMYSATTRQVETELFPYLRHFGLRFYAYNP 127
>L35546-1|AAA65028.1| 274|Homo sapiens gamma-glutamylcysteine
synthetase light subunit protein.
Length = 274
Score = 35.1 bits (77), Expect = 0.28
Identities = 29/132 (21%), Positives = 64/132 (48%), Gaps = 3/132 (2%)
Frame = +1
Query: 277 REELFVTTKLWN-DKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYL 453
REE+ V+ KL+ + ++ A+ + LG+ +D +I P D ++++L
Sbjct: 86 REEMKVSAKLFIVESNSSSSTRSAVDMACSVLGVAQLDSVIIASPPIE--DGVNLSLEHL 143
Query: 454 ET-WQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEP-LVAH 627
+ W+ +++ Q +IG S+ + TQ+ +L + ++P NQ+ + P L A
Sbjct: 144 QPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNLASCCVMPPDLTAF 203
Query: 628 CQSLGIAVMAYS 663
+ I ++ ++
Sbjct: 204 AKQFDIQLLTHN 215
>CR541833-1|CAG46632.1| 274|Homo sapiens GCLM protein.
Length = 274
Score = 35.1 bits (77), Expect = 0.28
Identities = 29/132 (21%), Positives = 64/132 (48%), Gaps = 3/132 (2%)
Frame = +1
Query: 277 REELFVTTKLWN-DKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYL 453
REE+ V+ KL+ + ++ A+ + LG+ +D +I P D ++++L
Sbjct: 86 REEMKVSAKLFIVESNSSSSTRSAVDMACSVLGVAQLDSVIIASPPIE--DGVNLSLEHL 143
Query: 454 ET-WQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEP-LVAH 627
+ W+ +++ Q +IG S+ + TQ+ +L + ++P NQ+ + P L A
Sbjct: 144 QPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNLASCCVMPPDLTAF 203
Query: 628 CQSLGIAVMAYS 663
+ I ++ ++
Sbjct: 204 AKQFDIQLLTHN 215
>BC041809-1|AAH41809.1| 274|Homo sapiens glutamate-cysteine ligase,
modifier subunit protein.
Length = 274
Score = 35.1 bits (77), Expect = 0.28
Identities = 29/132 (21%), Positives = 64/132 (48%), Gaps = 3/132 (2%)
Frame = +1
Query: 277 REELFVTTKLWN-DKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYL 453
REE+ V+ KL+ + ++ A+ + LG+ +D +I P D ++++L
Sbjct: 86 REEMKVSAKLFIVESNSSSSTRSAVDMACSVLGVAQLDSVIIASPPIE--DGVNLSLEHL 143
Query: 454 ET-WQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEP-LVAH 627
+ W+ +++ Q +IG S+ + TQ+ +L + ++P NQ+ + P L A
Sbjct: 144 QPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNLASCCVMPPDLTAF 203
Query: 628 CQSLGIAVMAYS 663
+ I ++ ++
Sbjct: 204 AKQFDIQLLTHN 215
>AY773965-1|AAV28733.1| 274|Homo sapiens glutamate-cysteine ligase,
modifier subunit protein.
Length = 274
Score = 35.1 bits (77), Expect = 0.28
Identities = 29/132 (21%), Positives = 64/132 (48%), Gaps = 3/132 (2%)
Frame = +1
Query: 277 REELFVTTKLWN-DKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYL 453
REE+ V+ KL+ + ++ A+ + LG+ +D +I P D ++++L
Sbjct: 86 REEMKVSAKLFIVESNSSSSTRSAVDMACSVLGVAQLDSVIIASPPIE--DGVNLSLEHL 143
Query: 454 ET-WQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEP-LVAH 627
+ W+ +++ Q +IG S+ + TQ+ +L + ++P NQ+ + P L A
Sbjct: 144 QPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNLASCCVMPPDLTAF 203
Query: 628 CQSLGIAVMAYS 663
+ I ++ ++
Sbjct: 204 AKQFDIQLLTHN 215
>AL117351-10|CAI22976.1| 274|Homo sapiens glutamate-cysteine
ligase, modifier subunit protein.
Length = 274
Score = 35.1 bits (77), Expect = 0.28
Identities = 29/132 (21%), Positives = 64/132 (48%), Gaps = 3/132 (2%)
Frame = +1
Query: 277 REELFVTTKLWN-DKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYL 453
REE+ V+ KL+ + ++ A+ + LG+ +D +I P D ++++L
Sbjct: 86 REEMKVSAKLFIVESNSSSSTRSAVDMACSVLGVAQLDSVIIASPPIE--DGVNLSLEHL 143
Query: 454 ET-WQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEP-LVAH 627
+ W+ +++ Q +IG S+ + TQ+ +L + ++P NQ+ + P L A
Sbjct: 144 QPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNLASCCVMPPDLTAF 203
Query: 628 CQSLGIAVMAYS 663
+ I ++ ++
Sbjct: 204 AKQFDIQLLTHN 215
>AL049796-2|CAI21813.1| 274|Homo sapiens glutamate-cysteine ligase,
modifier subunit protein.
Length = 274
Score = 35.1 bits (77), Expect = 0.28
Identities = 29/132 (21%), Positives = 64/132 (48%), Gaps = 3/132 (2%)
Frame = +1
Query: 277 REELFVTTKLWN-DKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYL 453
REE+ V+ KL+ + ++ A+ + LG+ +D +I P D ++++L
Sbjct: 86 REEMKVSAKLFIVESNSSSSTRSAVDMACSVLGVAQLDSVIIASPPIE--DGVNLSLEHL 143
Query: 454 ET-WQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEP-LVAH 627
+ W+ +++ Q +IG S+ + TQ+ +L + ++P NQ+ + P L A
Sbjct: 144 QPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNLASCCVMPPDLTAF 203
Query: 628 CQSLGIAVMAYS 663
+ I ++ ++
Sbjct: 204 AKQFDIQLLTHN 215
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 119,572,870
Number of Sequences: 237096
Number of extensions: 2620828
Number of successful extensions: 6059
Number of sequences better than 10.0: 116
Number of HSP's better than 10.0 without gapping: 5636
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5862
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9311505506
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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