Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P07_F_F19
(741 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q16836 Cluster: Hydroxyacyl-coenzyme A dehydrogenase, m... 252 5e-66
UniRef50_P34439 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenas... 233 4e-60
UniRef50_Q4DMG1 Cluster: Short chain 3-hydroxyacyl-coa dehydroge... 217 2e-55
UniRef50_Q4PFL4 Cluster: Putative uncharacterized protein; n=1; ... 211 1e-53
UniRef50_Q5KBI5 Cluster: Short chain 3-hydroxyacyl-CoA dehydroge... 209 5e-53
UniRef50_Q0YNQ2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 197 3e-49
UniRef50_Q84T13 Cluster: L-3-hydroxyacyl-CoA dehydrogenase subun... 194 1e-48
UniRef50_O44608 Cluster: Hydroxy-acyl-coa dehydrogenase protein ... 191 2e-47
UniRef50_Q1ISD6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 179 8e-44
UniRef50_O29077 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; c... 177 2e-43
UniRef50_Q67SZ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; S... 177 2e-43
UniRef50_A1SSP5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 177 2e-43
UniRef50_Q9KBD3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=8... 175 1e-42
UniRef50_UPI00015BAF7B Cluster: 3-hydroxyacyl-CoA dehydrogenase,... 174 2e-42
UniRef50_P45364 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 174 2e-42
UniRef50_Q8XI27 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase N... 171 2e-41
UniRef50_Q891F6 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=3... 169 5e-41
UniRef50_P45856 Cluster: Probable 3-hydroxybutyryl-CoA dehydroge... 169 6e-41
UniRef50_Q978T2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=5; A... 168 1e-40
UniRef50_A7D676 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 168 1e-40
UniRef50_Q97UK9 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2; S... 168 1e-40
UniRef50_Q1IIH2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5... 167 2e-40
UniRef50_O28011 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; A... 167 2e-40
UniRef50_Q5L0D2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3... 165 8e-40
UniRef50_Q9HKW7 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenas... 164 2e-39
UniRef50_Q9HRI4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7; c... 163 3e-39
UniRef50_Q1AV58 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 163 4e-39
UniRef50_Q1QBD7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 163 5e-39
UniRef50_A0RUN1 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C... 163 5e-39
UniRef50_P76083 Cluster: Probable 3-hydroxybutyryl-CoA dehydroge... 163 5e-39
UniRef50_A2TU34 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4... 161 1e-38
UniRef50_Q11E57 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 161 2e-38
UniRef50_A6ERZ1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 159 7e-38
UniRef50_O30218 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; A... 158 2e-37
UniRef50_Q6KYW3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 157 4e-37
UniRef50_A0LSM1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5... 156 5e-37
UniRef50_Q47M90 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5... 155 8e-37
UniRef50_Q397D0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3... 155 1e-36
UniRef50_Q39NP5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5... 155 1e-36
UniRef50_A3YFA8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 155 1e-36
UniRef50_Q2J6P6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=10; ... 153 4e-36
UniRef50_Q1ATL4 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 153 6e-36
UniRef50_Q5KYB5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=6... 152 8e-36
UniRef50_A0QZR0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 150 3e-35
UniRef50_Q5V357 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; H... 150 4e-35
UniRef50_Q45223 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=9... 150 4e-35
UniRef50_A0IJE2 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 149 5e-35
UniRef50_Q9YBW6 Cluster: 3-hydroxyacyl-CoA dehydrogenase/3-hydro... 149 7e-35
UniRef50_Q11E55 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 149 9e-35
UniRef50_Q9XA30 Cluster: Putative 3-Hydroxyacyl-CoA dehydrogenas... 146 4e-34
UniRef50_A1SPQ6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3... 146 4e-34
UniRef50_Q5UWD9 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; c... 146 4e-34
UniRef50_A5V4A1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 146 7e-34
UniRef50_Q5V0V6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 145 1e-33
UniRef50_Q8FUX6 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 144 2e-33
UniRef50_A0LPA1 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 144 2e-33
UniRef50_Q8FX64 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 144 3e-33
UniRef50_Q12D24 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 144 3e-33
UniRef50_Q8YB80 Cluster: 3-HYDROXYBUTYRYL-COA DEHYDROGENASE; n=3... 143 5e-33
UniRef50_Q9RUA4 Cluster: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA... 142 8e-33
UniRef50_Q11TH9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 142 8e-33
UniRef50_Q1GNH9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=7... 142 1e-32
UniRef50_Q4J6T7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 142 1e-32
UniRef50_Q0LZ25 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 140 4e-32
UniRef50_A4ALU9 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like pr... 140 4e-32
UniRef50_A1IEK7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 140 4e-32
UniRef50_Q8FRT3 Cluster: Putative 3-hydroxybutyryl-CoA dehydroge... 139 6e-32
UniRef50_Q2B4D1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 139 6e-32
UniRef50_A6CP14 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 139 8e-32
UniRef50_A0QZQ9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 138 1e-31
UniRef50_Q3IIH0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4... 138 2e-31
UniRef50_A1BCA2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 137 2e-31
UniRef50_O29815 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; A... 136 4e-31
UniRef50_Q06BB6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 136 5e-31
UniRef50_Q6MM12 Cluster: Fatty oxidation complex, alpha subunit;... 135 9e-31
UniRef50_Q6V1N6 Cluster: PlmT8; n=1; Streptomyces sp. HK803|Rep:... 135 1e-30
UniRef50_A0ISW5 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 135 1e-30
UniRef50_Q5NW50 Cluster: DitN-like 3-hydroxyacyl-CoA dehydrogena... 134 2e-30
UniRef50_A0K022 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 134 2e-30
UniRef50_Q7WCB1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4... 134 3e-30
UniRef50_Q9ADL9 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase; ... 132 7e-30
UniRef50_Q0SEV8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3... 132 1e-29
UniRef50_Q8W1L6 Cluster: Peroxisomal fatty acid beta-oxidation m... 132 1e-29
UniRef50_Q39TJ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like; n... 131 2e-29
UniRef50_A0W3T3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 131 2e-29
UniRef50_A3M4C7 Cluster: PaaC; n=1; Acinetobacter baumannii ATCC... 130 3e-29
UniRef50_A4FGV2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 130 5e-29
UniRef50_A5V327 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 126 6e-28
UniRef50_Q7VRZ0 Cluster: Probable enoyl-CoA hydratase/3-hydroxya... 125 1e-27
UniRef50_Q2S2J8 Cluster: Fatty oxidation complex, alpha subunit;... 125 1e-27
UniRef50_Q668V1 Cluster: Fatty acid oxidation complex subunit al... 124 3e-27
UniRef50_Q5P5K3 Cluster: Alpha-subunit of fatty acid oxidation c... 123 4e-27
UniRef50_A5D5N2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 123 5e-27
UniRef50_Q64428 Cluster: Trifunctional enzyme subunit alpha, mit... 123 5e-27
UniRef50_Q93HI5 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2; A... 122 7e-27
UniRef50_Q67L77 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 122 7e-27
UniRef50_A0LDJ8 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 122 7e-27
UniRef50_A0HAN1 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 122 7e-27
UniRef50_Q9HJM0 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase r... 122 7e-27
UniRef50_Q47DJ5 Cluster: Enoyl-CoA hydratase/isomerase:3-hydroxy... 122 1e-26
UniRef50_O69856 Cluster: Fatty acid oxidation complex alpha-subu... 122 1e-26
UniRef50_Q6D2L7 Cluster: Fatty acid oxidation complex subunit al... 122 1e-26
UniRef50_Q8ZAN0 Cluster: Fatty acid oxidation complex subunit al... 122 1e-26
UniRef50_A0Z5J4 Cluster: Enoyl-CoA hydratase; n=2; unclassified ... 121 2e-26
UniRef50_Q12AF3 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 120 3e-26
UniRef50_A4YDR4 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 120 3e-26
UniRef50_Q2W2Y1 Cluster: Glyoxysomal fatty acid beta-oxidation m... 120 4e-26
UniRef50_A3ZYI9 Cluster: Fatty oxidation complex, alpha subunit ... 120 4e-26
UniRef50_A1FD08 Cluster: 3-hydroxybutyryl-CoA epimerase; n=13; c... 120 4e-26
UniRef50_A7PEM6 Cluster: Chromosome chr11 scaffold_13, whole gen... 120 4e-26
UniRef50_Q9L6L5 Cluster: Fatty acid oxidation complex subunit al... 120 4e-26
UniRef50_Q5LVD0 Cluster: Enoyl-CoA hydratase/isomerase/3-hydroxy... 119 9e-26
UniRef50_Q0SCS0 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2; A... 119 9e-26
UniRef50_A1SXV8 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 119 9e-26
UniRef50_A6WDS7 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 118 1e-25
UniRef50_A5N111 Cluster: Hbd2; n=5; Clostridiales|Rep: Hbd2 - Cl... 117 3e-25
UniRef50_Q1Z537 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 116 5e-25
UniRef50_A5IDB6 Cluster: 3-hydroxyacyl CoA dehydrogenase; n=9; G... 116 5e-25
UniRef50_P40939 Cluster: Trifunctional enzyme subunit alpha, mit... 116 5e-25
UniRef50_O29062 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; A... 116 8e-25
UniRef50_Q2SGR6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; H... 115 1e-24
UniRef50_A1VP66 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 115 1e-24
UniRef50_A4RUY4 Cluster: Predicted protein; n=5; cellular organi... 115 1e-24
UniRef50_A3TT55 Cluster: Putative fatty acid oxidation complex a... 115 1e-24
UniRef50_A6X670 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 114 2e-24
UniRef50_A1SEZ9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 114 2e-24
UniRef50_Q13I86 Cluster: 3-hydroxybutyryl-CoA epimerase; n=11; B... 114 2e-24
UniRef50_A3T2M8 Cluster: Enoyl-CoA hydratase/isomerase/3-hydroxy... 114 2e-24
UniRef50_Q89SH2 Cluster: Blr2428 protein; n=7; Rhizobiales|Rep: ... 113 4e-24
UniRef50_A0LI43 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 112 1e-23
UniRef50_A7HHZ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 111 2e-23
UniRef50_A4BL13 Cluster: Fatty oxidation complex, alpha subunit;... 111 2e-23
UniRef50_Q0SEM1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 111 2e-23
UniRef50_A1FNB9 Cluster: 3-hydroxyacyl-CoA dehydrogenase precurs... 111 2e-23
UniRef50_Q3KCL0 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 110 3e-23
UniRef50_Q1GGC1 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 110 3e-23
UniRef50_Q83DW6 Cluster: Fatty oxidation complex, alpha subunit;... 109 7e-23
UniRef50_Q5P039 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; P... 109 7e-23
UniRef50_Q1YTH7 Cluster: Fatty oxidation complex, alpha subunit;... 108 1e-22
UniRef50_Q1D1F2 Cluster: Fatty oxidation complex, alpha subunit ... 108 1e-22
UniRef50_A4BGI3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; R... 108 1e-22
UniRef50_Q1IMY8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 108 2e-22
UniRef50_A0JVH8 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 108 2e-22
UniRef50_UPI0000E4974C Cluster: PREDICTED: hypothetical protein;... 107 2e-22
UniRef50_Q3JZL6 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati... 107 2e-22
UniRef50_A5WEP3 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 107 2e-22
UniRef50_A4SW27 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7; B... 107 2e-22
UniRef50_A1IDF2 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C... 107 2e-22
UniRef50_Q11BV6 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 107 4e-22
UniRef50_Q8PMV7 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7; X... 106 5e-22
UniRef50_Q11ME9 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 106 5e-22
UniRef50_Q28UL9 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 105 9e-22
UniRef50_Q08426 Cluster: Peroxisomal bifunctional enzyme (PBE) (... 105 9e-22
UniRef50_A6UH30 Cluster: 3-hydroxybutyryl-CoA epimerase; n=2; Si... 105 2e-21
UniRef50_A4WWF6 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 105 2e-21
UniRef50_O17761 Cluster: Putative uncharacterized protein ech-8;... 105 2e-21
UniRef50_Q5LVG3 Cluster: Enoyl-CoA hydratase/isomerase/3-hydroxy... 104 2e-21
UniRef50_Q4Q939 Cluster: Trifunctional enzyme alpha subunit, mit... 104 2e-21
UniRef50_A7INS1 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 104 3e-21
UniRef50_Q73Q34 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati... 103 6e-21
UniRef50_Q7D836 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 102 1e-20
UniRef50_Q39CK1 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=44; ... 101 1e-20
UniRef50_Q4REL3 Cluster: Chromosome 10 SCAF15123, whole genome s... 84 1e-20
UniRef50_Q9RZ10 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati... 101 2e-20
UniRef50_Q0EXX8 Cluster: Fatty oxidation complex, alpha subunit;... 100 3e-20
UniRef50_Q3A7N5 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 100 4e-20
UniRef50_A6FFH1 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenas... 100 4e-20
UniRef50_Q6N3H7 Cluster: Enoyl-CoA hydratase; n=26; Bacteria|Rep... 99 6e-20
UniRef50_Q0RL76 Cluster: Putative 3-hydroxybutyryl-CoA dehydroge... 99 6e-20
UniRef50_A3QGY2 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 99 6e-20
UniRef50_A5ULU2 Cluster: 3-hydroxyacyl-CoA dehydrogenase, FadB; ... 100 7e-20
UniRef50_Q7WIS8 Cluster: Putative enoyl-CoA isomerase; n=2; Bord... 99 1e-19
UniRef50_Q2S396 Cluster: 3-hydroxyacyl-CoA dehydrogenase, C-term... 99 1e-19
UniRef50_Q1DAC1 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 99 1e-19
UniRef50_A0JTB4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=5; A... 99 1e-19
UniRef50_Q28N18 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 99 1e-19
UniRef50_A5VHQ1 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 99 1e-19
UniRef50_A0J682 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 99 1e-19
UniRef50_Q988C8 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1... 98 2e-19
UniRef50_Q5KVJ3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=16; ... 98 2e-19
UniRef50_A1SQH4 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 98 2e-19
UniRef50_A6GBG1 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C... 97 3e-19
UniRef50_Q5LKF7 Cluster: Fatty oxidation complex, alpha subunit;... 97 4e-19
UniRef50_Q2SGN8 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; H... 97 4e-19
UniRef50_Q0YNJ7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 97 4e-19
UniRef50_Q4FL01 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; B... 95 1e-18
UniRef50_Q89HA7 Cluster: Blr6087 protein; n=6; Proteobacteria|Re... 95 2e-18
UniRef50_Q24N80 Cluster: Putative uncharacterized protein; n=1; ... 95 2e-18
UniRef50_A5IPA0 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 95 2e-18
UniRef50_Q1LBV6 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 95 2e-18
UniRef50_A6GC68 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 95 2e-18
UniRef50_A3U7V8 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C... 95 2e-18
UniRef50_Q128W2 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 94 3e-18
UniRef50_Q6SEY0 Cluster: 3-hydroxyacyl-CoA dehydrogenase domain ... 94 4e-18
UniRef50_UPI00006A277A Cluster: UPI00006A277A related cluster; n... 93 6e-18
UniRef50_Q0SJP3 Cluster: Bifunctional 3-hydroxyacyl-CoA dehydrog... 91 2e-17
UniRef50_Q0AI36 Cluster: 3-hydroxybutyryl-CoA epimerase; n=3; Ni... 91 2e-17
UniRef50_Q68WH7 Cluster: Putative fatty acid oxidation complex t... 91 2e-17
UniRef50_A0GEI2 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 91 3e-17
UniRef50_Q1NHB4 Cluster: Fatty oxidation complex, alpha subunit;... 91 3e-17
UniRef50_A6DTH3 Cluster: 3-hydroxyacyl-CoA dehydrogenase, C-term... 91 3e-17
UniRef50_A3N0P8 Cluster: Putative fatty acid oxidation complex a... 90 5e-17
UniRef50_UPI0000588BF0 Cluster: PREDICTED: similar to 3-hydroxya... 89 8e-17
UniRef50_Q392L7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=9... 89 8e-17
UniRef50_Q9UX37 Cluster: 3-hydroxyacyl-CoA-dehydrogenase; n=4; S... 89 8e-17
UniRef50_A1I839 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 89 1e-16
UniRef50_Q0SA65 Cluster: Possible 3-hydroxybutyryl-CoA dehydroge... 88 2e-16
UniRef50_Q5P5K6 Cluster: Fusion of 3-hydroxyacyl-CoA dehydrogena... 88 2e-16
UniRef50_Q02A28 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 87 3e-16
UniRef50_Q01UM7 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; S... 87 4e-16
UniRef50_Q7UXV2 Cluster: Fatty oxidation complex alpha subunit; ... 86 7e-16
UniRef50_Q1INT0 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 86 7e-16
UniRef50_Q01V22 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 86 7e-16
UniRef50_Q46MP3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4... 86 1e-15
UniRef50_A1CC71 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati... 86 1e-15
UniRef50_Q0RVG8 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; R... 85 1e-15
UniRef50_A3ZZK1 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1... 85 1e-15
UniRef50_A3JQP6 Cluster: Acetoacetyl-CoA reductase; n=2; Alphapr... 85 1e-15
UniRef50_Q4J0Z7 Cluster: 3-hydroxyacyl-CoA dehydrogenase, C-term... 85 2e-15
UniRef50_Q97HK2 Cluster: 3-Hydroxyacyl-CoA dehydrogenase; n=1; C... 85 2e-15
UniRef50_Q39D25 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=48; ... 85 2e-15
UniRef50_A4FJS5 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 85 2e-15
UniRef50_Q160J3 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 84 3e-15
UniRef50_Q0FMY4 Cluster: Enoyl-CoA hydratase; n=1; Roseovarius s... 84 3e-15
UniRef50_Q14G85 Cluster: Fusion product of 3-hydroxacyl-CoA dehy... 83 9e-15
UniRef50_Q0LRY2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 83 9e-15
UniRef50_A5UXI1 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 83 9e-15
UniRef50_A4SW21 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 83 9e-15
UniRef50_A3VIL7 Cluster: Enoyl-CoA hydratase/isomerase:3-hydroxy... 83 9e-15
UniRef50_Q8G825 Cluster: Possible butyryl-CoA dehydrogenase; n=2... 82 1e-14
UniRef50_A1WHE6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; V... 81 2e-14
UniRef50_Q5LPZ1 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 80 5e-14
UniRef50_O28262 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2; A... 80 6e-14
UniRef50_A4FKS0 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 79 9e-14
UniRef50_Q11EZ3 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 79 1e-13
UniRef50_Q0FUM2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 79 1e-13
UniRef50_A6C4K6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 79 1e-13
UniRef50_Q092W5 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C... 79 1e-13
UniRef50_A7HED1 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 78 3e-13
UniRef50_A1B712 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 77 3e-13
UniRef50_UPI00005102FD Cluster: COG1250: 3-hydroxyacyl-CoA dehyd... 77 6e-13
UniRef50_Q8FRN7 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 76 8e-13
UniRef50_A1IFR8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 76 8e-13
UniRef50_Q8KUG1 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=8; A... 76 1e-12
UniRef50_A5A8P0 Cluster: Putative uncharacterized protein; n=3; ... 76 1e-12
UniRef50_Q5V581 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; H... 76 1e-12
UniRef50_A5V325 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 75 1e-12
UniRef50_A0PRD1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase FadB... 75 2e-12
UniRef50_A3M445 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 75 2e-12
UniRef50_A1FMQ0 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 75 2e-12
UniRef50_Q98LG2 Cluster: Mll1034 protein; n=5; Alphaproteobacter... 74 3e-12
UniRef50_Q586V7 Cluster: Enoyl-CoA hydratase/Enoyl-CoA isomerase... 74 3e-12
UniRef50_A4R503 Cluster: Putative uncharacterized protein; n=3; ... 72 1e-11
UniRef50_O29090 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; A... 72 1e-11
UniRef50_Q0C7S2 Cluster: Putative uncharacterized protein; n=1; ... 72 2e-11
UniRef50_Q62DG4 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 71 2e-11
UniRef50_Q9Y2S2 Cluster: Lambda-crystallin homolog; n=30; Coelom... 71 2e-11
UniRef50_A7SBT1 Cluster: Predicted protein; n=2; Nematostella ve... 71 3e-11
UniRef50_Q0UZL9 Cluster: Putative uncharacterized protein; n=1; ... 71 3e-11
UniRef50_A3VGB5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 70 5e-11
UniRef50_Q0FUQ2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 69 1e-10
UniRef50_A1B801 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 67 4e-10
UniRef50_Q2J5F5 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 67 5e-10
UniRef50_Q39LC4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; B... 66 6e-10
UniRef50_A2QA05 Cluster: Catalytic activity:; n=4; Trichocomacea... 66 6e-10
UniRef50_Q396V2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=9; B... 66 1e-09
UniRef50_A5G288 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 66 1e-09
UniRef50_Q9VXI1 Cluster: CG9914-PA; n=5; Diptera|Rep: CG9914-PA ... 65 1e-09
UniRef50_A3YAS5 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 65 2e-09
UniRef50_UPI000023E2B1 Cluster: hypothetical protein FG00090.1; ... 64 3e-09
UniRef50_Q2CEL4 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 64 3e-09
UniRef50_UPI000050F939 Cluster: COG1250: 3-hydroxyacyl-CoA dehyd... 64 5e-09
UniRef50_Q1YHC5 Cluster: Putative 3-hydroxybutyryl-CoA dehydroge... 63 6e-09
UniRef50_Q1RLR0 Cluster: LOC570274 protein; n=4; Clupeocephala|R... 63 8e-09
UniRef50_Q39HR3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=24; ... 63 8e-09
UniRef50_Q1GEJ8 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 62 1e-08
UniRef50_Q67QQ5 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 62 1e-08
UniRef50_A6GIL3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 62 2e-08
UniRef50_Q4Q3S6 Cluster: Enoyl-CoA hydratase/Enoyl-CoA isomerase... 62 2e-08
UniRef50_A2QXC7 Cluster: Contig An11c0270, complete genome. prec... 62 2e-08
UniRef50_Q7WLK3 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 61 2e-08
UniRef50_Q5LTH8 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 61 2e-08
UniRef50_Q5HKI5 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 61 3e-08
UniRef50_Q2UUZ5 Cluster: RIB40 genomic DNA, SC009; n=4; Trichoco... 61 3e-08
UniRef50_A2QCM7 Cluster: Catalytic activity: precursor; n=5; Tri... 61 3e-08
UniRef50_Q876X5 Cluster: Dehydrogenase; n=7; Pezizomycotina|Rep:... 60 4e-08
UniRef50_Q7RZ80 Cluster: Putative uncharacterized protein NCU043... 58 2e-07
UniRef50_Q28KL8 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 58 2e-07
UniRef50_A3A5G7 Cluster: Putative uncharacterized protein; n=1; ... 56 1e-06
UniRef50_Q5P607 Cluster: Fusion of 3-hydroxyacyl-CoA dehydrogena... 54 4e-06
UniRef50_Q8EYS5 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=4; L... 52 2e-05
UniRef50_Q0FVZ4 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 50 6e-05
UniRef50_A3K5J4 Cluster: Putative fatty acid oxidation complex a... 50 6e-05
UniRef50_Q6MQ66 Cluster: Putative lipopolysaccharide heptosyltra... 41 0.037
UniRef50_Q93E13 Cluster: FadB; n=1; Rhizobium leguminosarum bv. ... 41 0.037
UniRef50_Q5T751 Cluster: Late cornified envelope protein 1C; n=3... 39 0.11
UniRef50_UPI00006A2DC9 Cluster: UPI00006A2DC9 related cluster; n... 39 0.15
UniRef50_Q24NA5 Cluster: Putative uncharacterized protein; n=1; ... 37 0.60
UniRef50_Q183H7 Cluster: Putative coproporphyrinogen III oxidase... 37 0.60
UniRef50_Q9XYB0 Cluster: PugilistDominant; n=2; Coelomata|Rep: P... 36 0.79
UniRef50_A5V511 Cluster: Enoyl-CoA hydratase/isomerase; n=1; Sph... 35 2.4
UniRef50_Q9MJ72 Cluster: ORF10; n=1; Physarum polycephalum|Rep: ... 34 3.2
UniRef50_Q7RMI4 Cluster: Putative uncharacterized protein PY0219... 34 3.2
UniRef50_A2QI39 Cluster: Similarity to hypothetical 3-hydroxyacy... 34 3.2
UniRef50_Q48E59 Cluster: Ferric uptake regulation protein; n=7; ... 34 4.2
UniRef50_Q4MR22 Cluster: Putative uncharacterized protein; n=1; ... 34 4.2
UniRef50_A7GU07 Cluster: Putative uncharacterized protein; n=1; ... 34 4.2
UniRef50_Q236S3 Cluster: Putative uncharacterized protein; n=1; ... 34 4.2
UniRef50_A0LNB4 Cluster: PAS/PAC sensor signal transduction hist... 33 5.6
UniRef50_Q5GA66 Cluster: Putative uncharacterized protein; n=1; ... 33 5.6
UniRef50_Q7RJS2 Cluster: Putative uncharacterized protein PY0318... 33 5.6
UniRef50_Q26216 Cluster: Rhoptry protein; n=69; Plasmodium (Vinc... 33 5.6
UniRef50_Q185D0 Cluster: Peptidase; n=11; Clostridiales|Rep: Pep... 33 7.4
UniRef50_A1BEY0 Cluster: TspO and MBR like proteins; n=3; Chloro... 33 7.4
UniRef50_P15265 Cluster: Sperm mitochondrial-associated cysteine... 33 7.4
UniRef50_Q5TA78 Cluster: Late cornified envelope protein 4A; n=2... 33 7.4
UniRef50_Q9N4M4 Cluster: Nuclear anchorage protein 1; n=4; Rhabd... 33 7.4
UniRef50_UPI00015BC8EA Cluster: UPI00015BC8EA related cluster; n... 33 9.7
UniRef50_UPI00006CEB72 Cluster: Leucine Rich Repeat family prote... 33 9.7
UniRef50_Q4RHT6 Cluster: Chromosome 8 SCAF15044, whole genome sh... 33 9.7
UniRef50_Q8F491 Cluster: Phosphomannomutase; n=4; Leptospira|Rep... 33 9.7
UniRef50_Q7NBP9 Cluster: Putative uncharacterized protein; n=1; ... 33 9.7
UniRef50_Q28PW6 Cluster: UspA; n=5; Rhodobacteraceae|Rep: UspA -... 33 9.7
UniRef50_Q03MK2 Cluster: Predicted protein; n=3; Streptococcus t... 33 9.7
UniRef50_A6TR33 Cluster: Sporulation stage III, protein AG; n=2;... 33 9.7
UniRef50_Q24298 Cluster: DE-cadherin precursor; n=5; Neoptera|Re... 33 9.7
>UniRef50_Q16836 Cluster: Hydroxyacyl-coenzyme A dehydrogenase,
mitochondrial precursor; n=40; Eukaryota|Rep:
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial
precursor - Homo sapiens (Human)
Length = 314
Score = 252 bits (618), Expect = 5e-66
Identities = 116/223 (52%), Positives = 166/223 (74%), Gaps = 1/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IAQV A G V +VD +IL K++K I+ +L +VAKK + ++P + FV+++L I
Sbjct: 42 IAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENPKAGDEFVEKTLSTIA 101
Query: 256 ISTKVEDSVNA-DLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
ST V++ DL++EAIVE L +K +LF +LDK A EHTI A+NTSS+ + +I +
Sbjct: 102 TSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIANATT 161
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
R+D+F GLHFFNPVPVM+L+EVIK+ S+ T+++++++ K++GK ++CKDTPGF+VNR
Sbjct: 162 RQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGKHPVSCKDTPGFIVNR 221
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLADY 741
+L PY EA+R+YERGDA+KEDID +KLGAG+PMGPF L DY
Sbjct: 222 LLVPYLMEAIRLYERGDASKEDIDTAMKLGAGYPMGPFELLDY 264
>UniRef50_P34439 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenase
F54C8.1; n=2; Caenorhabditis|Rep: Probable
3-hydroxyacyl-CoA dehydrogenase F54C8.1 - Caenorhabditis
elegans
Length = 298
Score = 233 bits (569), Expect = 4e-60
Identities = 112/223 (50%), Positives = 159/223 (71%), Gaps = 1/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IAQVTA +G NV + D+ + L++A K+I ++ ++KK D K + FV ++ RIK
Sbjct: 26 IAQVTASSGFNVMLADVNKKALDRAMKAISQSVTHLSKKQKGTDKEKSD-FVTLTMSRIK 84
Query: 256 ISTKVEDSV-NADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
V +V +ADLIIEA +E +D+K+ +F ++++ + +IL TNTSS + + G++
Sbjct: 85 TCNNVSTAVADADLIIEAAIENIDLKRGIFAQIEQSCKKDSILTTNTSSFLLEDVAKGLQ 144
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
K +FGGLHFFNPVPVM+LLEVI+SD S++TY ++++G +VGKT + CKD+PGF+VNR
Sbjct: 145 DKTRFGGLHFFNPVPVMKLLEVIRSDDTSDETYATLIKFGTAVGKTTVACKDSPGFIVNR 204
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLADY 741
+L PY EA RMYERGDA+ DID +KLGAG PMGPF LADY
Sbjct: 205 LLIPYFFEAARMYERGDASMTDIDEAMKLGAGHPMGPFELADY 247
>UniRef50_Q4DMG1 Cluster: Short chain 3-hydroxyacyl-coa
dehydrogenase, putative; n=2; Trypanosoma cruzi|Rep:
Short chain 3-hydroxyacyl-coa dehydrogenase, putative -
Trypanosoma cruzi
Length = 320
Score = 217 bits (531), Expect = 2e-55
Identities = 105/222 (47%), Positives = 151/222 (68%), Gaps = 1/222 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IAQV AQAG T+V++ E L+ ++KSI+++L R+ KK Y D K++ FV E++ RI
Sbjct: 47 IAQVNAQAGIPTTVVEVSQERLSASRKSIESSLSRIGKKQYPGDDQKMKAFVDETVSRIT 106
Query: 256 ISTKVEDSV-NADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
+T + NA LI+EAI+E +D K+ L+ K+D +AP+ + TNTSS+SV +
Sbjct: 107 FTTDERLAASNASLIVEAILEDIDAKKVLWRKVDGMAPKECVFCTNTSSLSVGEQAAVTG 166
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
R D+F GLHFF+PVP+M+L+EV+K+ S+ T ++E+ K + K + DT GF+VNR
Sbjct: 167 RPDRFAGLHFFSPVPMMKLVEVVKAAKTSQSTLDRILEYAKMLNKQPVMATDTKGFIVNR 226
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+L PY EA R+ ERGDAT ED+D+ +KLG G PMGPF LAD
Sbjct: 227 LLIPYELEACRIVERGDATVEDVDLAMKLGCGHPMGPFVLAD 268
>UniRef50_Q4PFL4 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 344
Score = 211 bits (516), Expect = 1e-53
Identities = 105/226 (46%), Positives = 154/226 (68%), Gaps = 5/226 (2%)
Frame = +1
Query: 76 IAQVTAQAGQ-NVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEG-FVKESLDR 249
IAQV A G+ NVT+ D+ + L Q I +LGR+ KK + + + +VK +D
Sbjct: 56 IAQVLAHKGKFNVTLSDVTDKALANGQTIISKSLGRIVKKSMAEASAEEQAQYVKGIVDS 115
Query: 250 IKISTKVEDSV-NADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSG 426
IK++T E +V + DL+IEAI+E + IK+DLF LD AP+ + A+NTSS+S+ +
Sbjct: 116 IKVTTDPEAAVKDTDLVIEAIIENVGIKKDLFGFLDGKAPKDALFASNTSSLSITDVAEA 175
Query: 427 I--KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGF 600
+ +R++ FGG H FNPVP M+L+EV+++ S DT+ ++ E K +GKT + C D+PGF
Sbjct: 176 VSAQRQELFGGFHAFNPVPQMKLVEVVRTTKTSNDTFDSLTEVAKRMGKTPVACIDSPGF 235
Query: 601 VVNRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+VNR+L PY EA+R+ ERG+AT +D+DI +KLGAG+PMGPF LAD
Sbjct: 236 IVNRLLVPYMLEAIRLVERGEATAKDVDIAMKLGAGYPMGPFELAD 281
>UniRef50_Q5KBI5 Cluster: Short chain 3-hydroxyacyl-CoA
dehydrogenase, putative; n=1; Filobasidiella
neoformans|Rep: Short chain 3-hydroxyacyl-CoA
dehydrogenase, putative - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 342
Score = 209 bits (511), Expect = 5e-53
Identities = 110/218 (50%), Positives = 142/218 (65%), Gaps = 3/218 (1%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IAQV AQ G V + D +P IL I +L RVAKK DD IEGF L I
Sbjct: 51 IAQVGAQNGLKVELTD-DPAILRNGINIISKSLARVAKKKSPDD---IEGFTNNVLKNIS 106
Query: 256 ISTKVEDSV-NADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGI- 429
+T +V NADL++EAI+E + +K+DLF LD A I ATNTSS+SV I
Sbjct: 107 TTTDSSQAVENADLVVEAIIESIKVKRDLFGFLDGKAKSDCIFATNTSSLSVTEIAEACS 166
Query: 430 -KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVV 606
+R+ KF GLHFFNPVP M+L+E+I++ S++TY+ + E +GK+ +TC DTPGF+V
Sbjct: 167 PERQAKFAGLHFFNPVPAMKLVEIIRTPQTSQETYETLREVTLQMGKSPVTCNDTPGFIV 226
Query: 607 NRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMG 720
NR+L PY EA+RM ERGDAT EDID ++LGAG+PMG
Sbjct: 227 NRLLVPYLLEAIRMIERGDATAEDIDTAMELGAGYPMG 264
>UniRef50_Q0YNQ2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=3; Geobacter|Rep: 3-hydroxybutyryl-CoA
dehydrogenase precursor - Geobacter sp. FRC-32
Length = 289
Score = 197 bits (480), Expect = 3e-49
Identities = 102/223 (45%), Positives = 140/223 (62%), Gaps = 1/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKI-EGFVKESLDRI 252
IAQ+ A AG V +VD+ E+ +A+K+I +L RV KK G I E ++E+L RI
Sbjct: 21 IAQIAAMAGLQVKVVDMSEEVWGRAKKTIVKSLERVVKK------GTITEKEMEETLGRI 74
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
ST V + I EA+ E +++K++LF KLD + + TI ATNTSSIS+ + + +K
Sbjct: 75 SFSTDVASLKDVPFIFEAVFEDINVKKELFAKLDAVCGDDTIYATNTSSISITEMAALVK 134
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
F G+HFFNPVPVM+L+EVI + + T +E K +GKT ITCKDTPGFVVNR
Sbjct: 135 NPANFIGMHFFNPVPVMKLVEVIPALQTAPATKDLALEMAKKIGKTAITCKDTPGFVVNR 194
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLADY 741
+ PY +A+R+ E G A+ EDID +KLG PMGP D+
Sbjct: 195 LFVPYIIDAVRLLEEGVASAEDIDTAMKLGCNMPMGPLEFQDF 237
>UniRef50_Q84T13 Cluster: L-3-hydroxyacyl-CoA dehydrogenase subunit
precursor; n=1; Euglena gracilis|Rep:
L-3-hydroxyacyl-CoA dehydrogenase subunit precursor -
Euglena gracilis
Length = 320
Score = 194 bits (474), Expect = 1e-48
Identities = 99/225 (44%), Positives = 139/225 (61%), Gaps = 3/225 (1%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKD---DPGKIEGFVKESLD 246
IAQ+TA AG V VD++ +L+K K+++ +L +VA K KD D E +
Sbjct: 37 IAQMTAAAGYKVVAVDIDANMLSKGIKAVEDSLSKVAAKAVKDGKADKATAEKNAADVRS 96
Query: 247 RIKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSG 426
RI S + + DL+IE+I+E L+IK+ F L K+A + ILA+NTSS + +G
Sbjct: 97 RITTSGDIGALSSCDLVIESIIEDLNIKKKFFADLGKVAGANAILASNTSSFPITQLGEA 156
Query: 427 IKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVV 606
R F GLHFFNPV +M+L+EVIK+ ED Y+ + KS+GK + C DTPGF+V
Sbjct: 157 SGRTSNFLGLHFFNPVQMMKLVEVIKTKDTKEDVYKLGFAFSKSIGKEPVACGDTPGFIV 216
Query: 607 NRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLADY 741
NR+L P+ A+ L M +RG A+ +DID+ + GAG PMGP LADY
Sbjct: 217 NRLLVPFLAQGLLMLDRGVASVQDIDVAMMYGAGMPMGPLTLADY 261
>UniRef50_O44608 Cluster: Hydroxy-acyl-coa dehydrogenase protein 1;
n=2; Caenorhabditis|Rep: Hydroxy-acyl-coa dehydrogenase
protein 1 - Caenorhabditis elegans
Length = 299
Score = 191 bits (465), Expect = 2e-47
Identities = 96/226 (42%), Positives = 141/226 (62%), Gaps = 4/226 (1%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKD---DPGKIEGFVKESLD 246
IAQV QAG V + + L +A+++I+ NL RVA K D +P +E + LD
Sbjct: 25 IAQVCLQAGYPVNLYGRSEKKLLEARETIKKNLIRVASKKKTDVPMEPAALEEIAQIQLD 84
Query: 247 RIKISTKVEDSV-NADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGS 423
++I T + + +A + IEA+ E LD+K D+F + K P++ +L TNTSS+ ++ +
Sbjct: 85 LLQIHTDIPSAAEDAAMAIEAVAENLDLKLDIFQTIQKTCPQNCMLITNTSSLKLSQMLP 144
Query: 424 GIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFV 603
I+ F GLHFFNPVPVM+L+EV+ +D S +T + + K + K + KDTPGF+
Sbjct: 145 VIQNPALFAGLHFFNPVPVMKLVEVVSTDETSPETTNFLFNFCKEIKKLPVAAKDTPGFI 204
Query: 604 VNRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLADY 741
VNR+L PY +++RM ERGDATKEDID ++ G +PMGP L DY
Sbjct: 205 VNRLLIPYLMDSIRMLERGDATKEDIDTAMRFGTSYPMGPIELCDY 250
>UniRef50_Q1ISD6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Acidobacteria bacterium Ellin345|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Acidobacteria bacterium (strain Ellin345)
Length = 293
Score = 179 bits (435), Expect = 8e-44
Identities = 90/223 (40%), Positives = 140/223 (62%), Gaps = 1/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKK-LYKDDPGKIEGFVKESLDRI 252
IAQ A AG V +++ E L++ ++ +L + A+K + P I R+
Sbjct: 18 IAQAAATAGFPVIVLEAEQRFLDRGFTGVERSLAKFAEKGTITESPDAIRA-------RL 70
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
K +T VED + D+IIEAI+E + K ++ L+K+A I A+NTSSIS+ + + K
Sbjct: 71 KGTTNVEDLADCDIIIEAILENVPEKHKMYAALEKVAKPDAIFASNTSSISITELMAATK 130
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
R ++F GLHFFNPVP+M+L+EVI++ S++ ++A +++G +GK + KD+ GF+VNR
Sbjct: 131 RPERFIGLHFFNPVPLMKLVEVIRTIATSDEVFEAAVDFGTKLGKVPVRTKDSSGFIVNR 190
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLADY 741
+L PY +A+R YE G + DID +KLG G+PMGPF L D+
Sbjct: 191 LLVPYLLDAIRAYEEGVGSIVDIDQAMKLGCGYPMGPFTLLDF 233
>UniRef50_O29077 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
cellular organisms|Rep: 3-hydroxyacyl-CoA dehydrogenase
- Archaeoglobus fulgidus
Length = 295
Score = 177 bits (432), Expect = 2e-43
Identities = 93/222 (41%), Positives = 141/222 (63%), Gaps = 1/222 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKI-EGFVKESLDRI 252
IAQV A+ G +V +VD+ E+L KA + I++ + + + K GK+ E K + RI
Sbjct: 21 IAQVAARTGYDVVMVDVSEEVLKKAMELIESGPFGLRRLVEK---GKMSEDEAKAVMARI 77
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
+ ST +E +AD IIEA+ EK D+K+ +F +LD++ TI+A+NTS+I ++ + + ++
Sbjct: 78 RTSTSLEALKDADFIIEAVTEKADLKKKIFAELDRICKPETIIASNTSAIMISDLATAVE 137
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
RKDKF G+H+FNP PVMRL+EVI+ S++T+ +E K +GK I D PGF R
Sbjct: 138 RKDKFIGMHWFNPAPVMRLIEVIRGALTSDETFNITVELSKKMGKIPIEAGDGPGFFTTR 197
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+ + EA+R++E G A ++ID KL GFPMGPF L D
Sbjct: 198 FINSWLVEAVRLFEIGIAGIKEIDEMCKLAFGFPMGPFELMD 239
>UniRef50_Q67SZ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Symbiobacterium thermophilum|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Symbiobacterium thermophilum
Length = 517
Score = 177 bits (431), Expect = 2e-43
Identities = 97/222 (43%), Positives = 137/222 (61%), Gaps = 1/222 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKI-EGFVKESLDRI 252
IAQV AQ+G +V + D++PE L +A ++++L R A + G+I + V E L RI
Sbjct: 16 IAQVAAQSGFDVLLYDVDPEALARALGRVESDLQRQAAR------GRIPDAQVAEVLGRI 69
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
+T + D AD +IEA E L++K+ LF +LD+L E +LATNTSS+SV IG+
Sbjct: 70 TTTTSLGDFAAADFVIEAAPEDLELKRRLFERLDRLCREDVVLATNTSSLSVTQIGALAG 129
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
R D+ G+HFFNPVP MRL+EV+ D E QA + +++GK + +DTPGF+VNR
Sbjct: 130 RADRVVGMHFFNPVPAMRLVEVVGGDASGEAALQATVSLAEAMGKVPVRVRDTPGFIVNR 189
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+ P++ EALR+ AT ID +L GF MGPF L D
Sbjct: 190 VARPFTGEALRLLGDQVATAAQIDRIARLACGFRMGPFELMD 231
Score = 45.6 bits (103), Expect = 0.001
Identities = 23/61 (37%), Positives = 32/61 (52%)
Frame = +1
Query: 556 SVGKTCITCKDTPGFVVNRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLA 735
S+G+ D+PG V R+L EA + G AT E ID ++LG +P+GP A
Sbjct: 416 SLGRDTEVVTDSPGLVAARLLACLINEAAFALQEGIATAEAIDTAMQLGLNYPLGPLEWA 475
Query: 736 D 738
D
Sbjct: 476 D 476
>UniRef50_A1SSP5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Psychromonas ingrahamii 37|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Psychromonas ingrahamii (strain 37)
Length = 511
Score = 177 bits (431), Expect = 2e-43
Identities = 97/222 (43%), Positives = 138/222 (62%), Gaps = 1/222 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKES-LDRI 252
IAQV AQ+G V + DL +A+++I+ L R KK G++E ES L RI
Sbjct: 21 IAQVAAQSGYQVYLFDLAKGKAEEAKENIEKQLERRVKK------GRMEQQTLESTLLRI 74
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
S+++ + +A+L+IEAIVE L+IKQ LF +L+ + ILA+NTSSIS+ AI S +K
Sbjct: 75 HCSSELSEIASANLVIEAIVENLEIKQGLFKELETICSADCILASNTSSISITAIASALK 134
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
++F GLHFFNP PVM+L+EVI+ +++ + +W +S GK + PGF+VNR
Sbjct: 135 SPERFIGLHFFNPAPVMKLVEVIQGVATADNIAETAQQWARSCGKKSVLACSIPGFIVNR 194
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+ P+ AE LR E AT +DID ++ AGF MGPF L D
Sbjct: 195 VARPFYAEGLRALEESVATIDDIDHLMRASAGFNMGPFELMD 236
Score = 47.6 bits (108), Expect = 3e-04
Identities = 23/53 (43%), Positives = 31/53 (58%)
Frame = +1
Query: 565 KTCITCKDTPGFVVNRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGP 723
K I KD PG +V R L S EAL + + A++ DIDI +K G +P+GP
Sbjct: 414 KQVILIKDYPGMIVWRTLSMLSNEALDLANKKGASEADIDIAMKSGVNYPLGP 466
>UniRef50_Q9KBD3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=8;
Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Bacillus halodurans
Length = 287
Score = 175 bits (425), Expect = 1e-42
Identities = 91/224 (40%), Positives = 138/224 (61%), Gaps = 2/224 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKES-LDRI 252
IA + A +G V ++DL+ L+ A + I + + K GK+ KE+ L RI
Sbjct: 18 IANLAAMSGLQVVLLDLDDNQLDIAWQKINTFMEKSVAK------GKMSEAEKEAALGRI 71
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
K +T E+ ADL+IEA++E LD+K+++F+ LD TI+ATNTSS+S+ I +
Sbjct: 72 KSTTTYEELAEADLVIEAVIENLDVKKEVFHTLDTCLANDTIIATNTSSMSITEIAAATN 131
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITC-KDTPGFVVN 609
R D+ G+HFFNP +M+L+EV++ S+DT + + ++ + + K I KDTPGF+VN
Sbjct: 132 RPDRVVGMHFFNPAQLMKLVEVVRGYQTSDDTVETVKQFARQLKKEPIEVKKDTPGFIVN 191
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLADY 741
RI+ P EA+++ E G A+ EDID + LG +PMGPF L DY
Sbjct: 192 RIMIPQFIEAIKLLEEGVASAEDIDKAVTLGLNYPMGPFTLQDY 235
>UniRef50_UPI00015BAF7B Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Ignicoccus hospitalis KIN4/I|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Ignicoccus hospitalis KIN4/I
Length = 683
Score = 174 bits (423), Expect = 2e-42
Identities = 95/228 (41%), Positives = 139/228 (60%), Gaps = 6/228 (2%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRV-AKKLYKDDPG----KIEGFVKES 240
IAQV A +G NV ++D++ E L++A + I+ +L ++ AK K+ P +IE V
Sbjct: 38 IAQVAAMSGLNVRMIDIKQEFLDRAMERIKESLEKLYAKGKLKEPPEEVLKRIETMVANP 97
Query: 241 LDRIKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIG 420
D S+ E + + D +IEA+ EKL++K+ +F+ LDK AP H ILA+NTSSI + I
Sbjct: 98 DDE---SSYAEAAKDVDFVIEAVPEKLELKRAVFSVLDKYAPPHAILASNTSSIPITEIA 154
Query: 421 SGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITC-KDTPG 597
KR DK G+HFFNP +++L+EV++ S++T + +E K +GK I KD PG
Sbjct: 155 KATKRPDKVVGMHFFNPPVILKLVEVVRGKETSDETVKITVELAKKMGKVPIVVNKDVPG 214
Query: 598 FVVNRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLADY 741
F+VNRI+ + E + ERG TKE +D L+ FPMG F LADY
Sbjct: 215 FIVNRIMARFLNEGCWLVERGVYTKEQVDAALRYKLNFPMGAFELADY 262
>UniRef50_P45364 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=13;
Clostridia|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Clostridium difficile
Length = 281
Score = 174 bits (423), Expect = 2e-42
Identities = 96/222 (43%), Positives = 131/222 (59%), Gaps = 1/222 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGK-IEGFVKESLDRI 252
I Q A G +V + ++K + NL ++ K GK ++ E L +
Sbjct: 15 IVQTFASCGHDVCLKSRTQGAIDKCLALLDKNLTKLVTK------GKWMKATKAEILSHV 68
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
+T ED + DLIIEA VE ++IK+D+F LD+L E TILATNTSS+S+ I S K
Sbjct: 69 SSTTNYEDLKDMDLIIEASVEDMNIKKDVFKLLDELCKEDTILATNTSSLSITEIASSTK 128
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
R DK G+HFFNPVP+M+L+EVI S+ T+ + E KS+ K + ++PGFVVNR
Sbjct: 129 RPDKVIGMHFFNPVPMMKLVEVISGQLTSKVTFDTVFELSKSINKVPVDVSESPGFVVNR 188
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
IL P EA+ +Y G A+KE+ID +KLGA PMGP L D
Sbjct: 189 ILIPMINEAVGIYADGVASKEEIDEAMKLGANHPMGPLALGD 230
>UniRef50_Q8XI27 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase
NAD-dependent; n=9; Clostridiales|Rep:
Beta-hydroxybutyryl-CoA dehydrogenase NAD-dependent -
Clostridium perfringens
Length = 282
Score = 171 bits (416), Expect = 2e-41
Identities = 90/222 (40%), Positives = 134/222 (60%), Gaps = 1/222 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKES-LDRI 252
I Q AQ G V + D++ E +++ I L ++ K GKI KE+ L +I
Sbjct: 16 IVQAFAQKGYEVIVRDIKDEFVDRGIAGINKGLTKLVSK------GKITEEDKEAVLSKI 69
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
+T + + + DL+IEA VE ++IK+ +F +LDK+ E TILA+NTSS+S+ + S
Sbjct: 70 TGTTDLGLAADCDLVIEAAVENMEIKKQIFAELDKICKEETILASNTSSLSITEVASATN 129
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
R D+ G+HFFNP +M+L+EVI+ S++T+ + +++GKT + + PGFVVNR
Sbjct: 130 RPDRVIGMHFFNPATIMKLVEVIRGMATSQETFDKVKAMSEAIGKTPVEVAEAPGFVVNR 189
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
IL P EA+ +Y G A+ EDID +KLGA PMGP L D
Sbjct: 190 ILIPMINEAIGIYAEGIASVEDIDTSMKLGANHPMGPLALGD 231
>UniRef50_Q891F6 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxybutyryl-coA dehydrogenase -
Clostridium tetani
Length = 282
Score = 169 bits (412), Expect = 5e-41
Identities = 86/223 (38%), Positives = 135/223 (60%), Gaps = 2/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKK--LYKDDPGKIEGFVKESLDR 249
IAQ A G V + D++ E + + K I+ L ++ K + ++D I G ++ ++D
Sbjct: 16 IAQAFAAKGYEVVLRDIKDEFVERGIKGIEKGLSKLVSKGRMAQEDMDSILGRIEGTVDL 75
Query: 250 IKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGI 429
K + + DL++EA +E ++IK+++F +LD++ TIL++NTSS+S+ I +
Sbjct: 76 NK-------AADCDLVVEAAIENMEIKREIFAELDRICKPETILSSNTSSLSITEIATAT 128
Query: 430 KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVN 609
R DK G+HFFNP PVM+L+E+I+ S++T+ A+ E ++GK + + PGFVVN
Sbjct: 129 NRPDKVIGMHFFNPAPVMKLIEIIRGMATSQETFDAVKEVSVAIGKDPVEVAEAPGFVVN 188
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
RIL P EA+ +Y G AT EDID + LGA PMGP L D
Sbjct: 189 RILIPMINEAIGIYAEGIATAEDIDKAMMLGANHPMGPLALGD 231
>UniRef50_P45856 Cluster: Probable 3-hydroxybutyryl-CoA
dehydrogenase; n=65; Bacteria|Rep: Probable
3-hydroxybutyryl-CoA dehydrogenase - Bacillus subtilis
Length = 287
Score = 169 bits (411), Expect = 6e-41
Identities = 94/223 (42%), Positives = 130/223 (58%), Gaps = 1/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGK-IEGFVKESLDRI 252
IAQ A AG V + D+ PE K ++ L R A+K GK E VK ++RI
Sbjct: 18 IAQTAADAGFYVRMYDVNPEAAEAGLKRLKKQLARDAEK------GKRTETEVKSVINRI 71
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
IS +E++ +AD++IEAI E + K ++F LD++ P HTILA+NTSS+ + I +
Sbjct: 72 SISQTLEEAEHADIVIEAIAENMAAKTEMFKTLDRICPPHTILASNTSSLPITEIAAVTN 131
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
R + G+HF NPVPVM+L+EVI+ SE+T +M + +GKT + D PGFV NR
Sbjct: 132 RPQRVIGMHFMNPVPVMKLVEVIRGLATSEETALDVMALAEKMGKTAVEVNDFPGFVSNR 191
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLADY 741
+L P EA+ G A E ID +KLG PMGP LAD+
Sbjct: 192 VLLPMINEAIYCVYEGVAKPEAIDEVMKLGMNHPMGPLALADF 234
>UniRef50_Q978T2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=5;
Archaea|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Thermoplasma volcanium
Length = 659
Score = 168 bits (409), Expect = 1e-40
Identities = 94/224 (41%), Positives = 137/224 (61%), Gaps = 2/224 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IA+ A AG +V + D+ ++L KA+ I A+L R+ K D K+ G RI
Sbjct: 18 IAETIALAGYDVNLEDISDDVLAKAKAEIDASLDRLVKSGKLSDKTKVLG-------RIH 70
Query: 256 ISTKVEDSV-NADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
T + +SV +ADL+IEA+ E LDIK+ +F +LD+ E ILATNTS+I + I G+K
Sbjct: 71 YFTSIPESVKDADLVIEAVPEILDIKRQVFAQLDQSTKEDAILATNTSNIRLTEIAEGVK 130
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCI-TCKDTPGFVVN 609
+K K G+HFFNP V++L+EVI+SD+ ++ ++A+ ++ K +GK I KDTPGFVVN
Sbjct: 131 KKGKVVGMHFFNPPVVLKLVEVIRSDYTEDEVFEAVYDFSKKIGKIPIKVYKDTPGFVVN 190
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLADY 741
RI P S + ++G A E++D G PMGP+ L DY
Sbjct: 191 RINAPESLYFCLVLDKGIAKPEEVD-RFARSQGLPMGPYELMDY 233
Score = 34.7 bits (76), Expect = 2.4
Identities = 15/34 (44%), Positives = 22/34 (64%)
Frame = +1
Query: 634 EALRMYERGDATKEDIDIGLKLGAGFPMGPFXLA 735
EA+++ E + EDI+IG+KLG P GP +A
Sbjct: 308 EAVKIIEEKIVSPEDIEIGVKLGMNRPFGPITVA 341
>UniRef50_A7D676 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Halorubrum lacusprofundi ATCC
49239|Rep: 3-hydroxyacyl-CoA dehydrogenase, NAD-binding
- Halorubrum lacusprofundi ATCC 49239
Length = 676
Score = 168 bits (409), Expect = 1e-40
Identities = 92/223 (41%), Positives = 138/223 (61%), Gaps = 2/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IA+V A AG +V + D+E E + I+ +LG++A+K D G+ E +LDR++
Sbjct: 34 IAEVAALAGYDVALRDIEEEFVQGGYDQIEWSLGKLAEK---DRIGEDEA--DAALDRVE 88
Query: 256 ISTKVEDSV-NADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
+EDS+ +AD+++E + EK+ IK+D+++++ + APE + TNTSS+S+ +
Sbjct: 89 AFVDLEDSLADADVVVEVVPEKMAIKKDVYDEVVEYAPEEAVFVTNTSSLSITELSEVTD 148
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITC-KDTPGFVVN 609
R ++F G+HFFNP M L+EVI H SEDT + + +S+GKT + KD+PGF+VN
Sbjct: 149 RPERFCGMHFFNPPVRMDLVEVISGKHTSEDTLELIEGLAESMGKTPVRVRKDSPGFIVN 208
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
RIL P EA + E GDAT E +D K G PMG F LAD
Sbjct: 209 RILVPLMNEAAWIVESGDATIETVDSTTKFDMGLPMGSFELAD 251
>UniRef50_Q97UK9 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2;
Sulfolobus|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Sulfolobus solfataricus
Length = 384
Score = 168 bits (408), Expect = 1e-40
Identities = 86/223 (38%), Positives = 138/223 (61%), Gaps = 1/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IA+V+A A NV++VD+ + LN+A++ I +L + +K G+I+ ++ + RI+
Sbjct: 18 IAEVSALANYNVSVVDISWDFLNRAKERIMESLNKFYEK------GQIKEKPEDIMKRIE 71
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
ST + +AD +IEA+ E +++K+ +F LD + P HT LA+NTSSI ++ I KR
Sbjct: 72 FSTSYDVMRDADFVIEAVPEIIELKRKVFETLDSITPSHTFLASNTSSIPISTIAEVTKR 131
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCK-DTPGFVVNR 612
K+K G+HFFNP P+M+L+E++ S + S++T + ++ K + K + K + PGFV NR
Sbjct: 132 KEKIIGMHFFNPPPIMKLVEIVPSKYTSDETIEVTIDLAKKMNKIPVKLKVEVPGFVSNR 191
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLADY 741
I EA R E G+AT E++D + G PMG F L+DY
Sbjct: 192 IFLRLMQEACREVEDGEATIEEVDSAARNGLKLPMGIFELSDY 234
>UniRef50_Q1IIH2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5;
cellular organisms|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Acidobacteria bacterium (strain
Ellin345)
Length = 282
Score = 167 bits (407), Expect = 2e-40
Identities = 92/223 (41%), Positives = 132/223 (59%), Gaps = 1/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGR-VAKKLYKDDPGKIEGFVKESLDRI 252
IA V A++G V + D++ E L++ +I+ NL R VAK + G++ + D I
Sbjct: 18 IAHVFAKSGYKVVLCDVKREFLDRGLATIKKNLEREVAKNKISQEQGQV------AADHI 71
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
+ + +D + D+++EA E+ +IK +LF LD + ILATNTSSIS+ I + K
Sbjct: 72 YPTLERKDLADCDIVVEAASERFEIKAELFRDLDSICRPDVILATNTSSISITKIAAVTK 131
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
R DK G+HFFNPVPVM+L+EVI+ S++TYQA+ + + KT + D PGFV NR
Sbjct: 132 RPDKVIGMHFFNPVPVMKLVEVIRGLATSDETYQAVKVLSEKLEKTPVEVNDAPGFVSNR 191
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLADY 741
+L P EA+ G AT E +D KLG PMGP LAD+
Sbjct: 192 VLMPLLNEAMYAVMEGVATPEAVDEVFKLGMAHPMGPLTLADF 234
>UniRef50_O28011 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 668
Score = 167 bits (407), Expect = 2e-40
Identities = 89/224 (39%), Positives = 143/224 (63%), Gaps = 2/224 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IA+V A AG NVT+ D++ E +++ I+ +L ++ +K GKI+ +E L RIK
Sbjct: 32 IAEVCAMAGYNVTMRDIKQEFVDRGMNMIKESLAKLEQK------GKIKS-AEEVLSRIK 84
Query: 256 ISTKVEDSV-NADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
+ +E++V +ADL+IEA+ E ++IK+ ++ ++DKLA I +NTS++ + +
Sbjct: 85 PTVDLEEAVKDADLVIEAVPEVVEIKKQVWEEVDKLAKPDCIFTSNTSTMRITMLADFTS 144
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITC-KDTPGFVVN 609
R +KF GLHFFNP +MRL+EVI+ + S++ ++E+ KS+GKT + KD PGF+VN
Sbjct: 145 RPEKFAGLHFFNPPVLMRLVEVIRGEKTSDEVMDLLVEFVKSIGKTPVRVEKDVPGFIVN 204
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLADY 741
R+ P S + + E+G AT E++D ++ G PMGPF L DY
Sbjct: 205 RVQAPASVLLMAILEKGIATPEEVDATVR-RLGLPMGPFELVDY 247
Score = 45.6 bits (103), Expect = 0.001
Identities = 30/88 (34%), Positives = 43/88 (48%), Gaps = 1/88 (1%)
Frame = +1
Query: 475 PVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCI-TCKDTPGFVVNRILXPYSAEALRMY 651
P L E++K++ + T Q +W K G+ I + K T EA+++
Sbjct: 270 PPKFLEEMVKANKLGRKTGQGFYDWSK--GRPQIDSSKATDKINPMDFTFVEINEAVKLV 327
Query: 652 ERGDATKEDIDIGLKLGAGFPMGPFXLA 735
E G AT +DID +KLG P GPF LA
Sbjct: 328 EMGVATPQDIDTAIKLGLNRPFGPFELA 355
>UniRef50_Q5L0D2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Geobacillus kaustophilus
Length = 281
Score = 165 bits (402), Expect = 8e-40
Identities = 87/222 (39%), Positives = 128/222 (57%), Gaps = 1/222 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IAQ A G+ V + D+ L S + +L R K G E + +L RI+
Sbjct: 17 IAQTAAMVGKTVYLYDVSEAALQNGLASAEKSLRRFVKT-----GGLSEPEARAALGRIR 71
Query: 256 ISTKVEDSVN-ADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
+ + ++V AD++IEA+ E L +K+D+F +LD+LA ILATNTS +SV A+ +
Sbjct: 72 STVDLAEAVRGADVVIEAVPENLALKKDVFQQLDQLAKPDAILATNTSELSVTALAAATN 131
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
R + G+H+FNP PVM+L+E++K + S+DT A+ +GK + KD GFV R
Sbjct: 132 RPENVIGMHWFNPAPVMKLIEIVKGETTSDDTVDAIRRLSVELGKETVVVKDRQGFVTTR 191
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
L + E +RMYE G A+ EDID ++LG +PMGP LAD
Sbjct: 192 ALAAHMIECIRMYEEGVASAEDIDKAVRLGLNYPMGPLELAD 233
>UniRef50_Q9HKW7 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenase;
n=2; Thermoplasmatales|Rep: Probable 3-hydroxyacyl-CoA
dehydrogenase - Thermoplasma acidophilum
Length = 291
Score = 164 bits (399), Expect = 2e-39
Identities = 84/219 (38%), Positives = 131/219 (59%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IAQV A++G VTI+D+ +IL A +SI+ GR E V + + +I+
Sbjct: 18 IAQVFARSGYPVTIIDVRDDILANAVRSIKE--GRYGLMNLVKKGTMTESEVDKIMGKIR 75
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
ST +AD+++EA+ E LD+K+ +F ++K E+ I+A+NTS I++ I +K+
Sbjct: 76 TSTSYGSLSDADIVVEAVPENLDLKRKVFIDIEKNVSENAIIASNTSGITIAEIAQDLKK 135
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRI 615
KD+ G+H+FNP +M+L+EV+++ SEDT ++++ + +GKT + D PGF R
Sbjct: 136 KDRAIGMHWFNPAGIMKLIEVVRAKMTSEDTISTVVDFSRRIGKTPVVVADVPGFFTTRF 195
Query: 616 LXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXL 732
+ + A+R YE ATK DID KL GFPMGPF L
Sbjct: 196 IEGWLLAAIRSYEANIATKADIDTMAKLAFGFPMGPFEL 234
>UniRef50_Q9HRI4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7;
cellular organisms|Rep: 3-hydroxyacyl-CoA dehydrogenase
- Halobacterium salinarium (Halobacterium halobium)
Length = 286
Score = 163 bits (397), Expect = 3e-39
Identities = 88/222 (39%), Positives = 126/222 (56%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IAQV A AG V + D+E E ++ SI+++L R DD + + +DRI
Sbjct: 22 IAQVAATAGYTVVMRDIEQEYVDAGFDSIESSLDRFVSN---DDLSEADA--DAIVDRIT 76
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
+T + + + D++IEA VE ++IKQD+F LD PE +LATNTS++S+ I S R
Sbjct: 77 GTTDLAELADCDVVIEAAVEDMEIKQDIFRDLDDALPEDVVLATNTSTLSITTIASVTDR 136
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRI 615
+ GLHF NPVP+M +EV+ + D + + K D PGFV NRI
Sbjct: 137 ASRVVGLHFMNPVPIMTGVEVVVGEKTDADVVAFAHALAEDLDKETWESDDKPGFVTNRI 196
Query: 616 LXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLADY 741
L P+ E +R ++ G A+K+DID G+KLG PMGP LAD+
Sbjct: 197 LMPWINEGVRAFDEGVASKDDIDTGMKLGTNVPMGPLELADH 238
>UniRef50_Q1AV58 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Rubrobacter xylanophilus DSM 9941|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 377
Score = 163 bits (396), Expect = 4e-39
Identities = 88/222 (39%), Positives = 131/222 (59%), Gaps = 1/222 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKES-LDRI 252
IAQ A G V +VD+ E L + +S++ANL R ++ G+I ++ L RI
Sbjct: 17 IAQSAAACGFEVALVDVSEEALERGMRSVRANLERRVER------GRISSEERDGVLGRI 70
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
T +E A L+IEA+VE + +K+++F L+++ E +LATNTSS+SV I + +
Sbjct: 71 STFTSLESCAGASLVIEAVVEDIGVKREVFRTLERVVGEEAVLATNTSSLSVAEISATTR 130
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
R ++ G+HFFNP PVMRL+EV++ E+ E + +GKT + DTPGF+VNR
Sbjct: 131 RPERVVGMHFFNPAPVMRLVEVVRGPRSGEEALARAEEAARRMGKTPVRVSDTPGFIVNR 190
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+ P+ EALR+ E G++ ID L+ GF MGP LAD
Sbjct: 191 VARPFYLEALRLAETGESPAR-IDASLR-ERGFRMGPLELAD 230
Score = 35.5 bits (78), Expect = 1.4
Identities = 17/43 (39%), Positives = 24/43 (55%)
Frame = +1
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
R++ EA E G A+ DID ++LGA +P GPF A+
Sbjct: 301 RVISCVVNEAFFALEEGVASAGDIDRAMQLGANYPKGPFAWAE 343
>UniRef50_Q1QBD7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=2; Psychrobacter|Rep: 3-hydroxybutyryl-CoA
dehydrogenase precursor - Psychrobacter cryohalolentis
(strain K5)
Length = 533
Score = 163 bits (395), Expect = 5e-39
Identities = 88/222 (39%), Positives = 129/222 (58%), Gaps = 1/222 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKI-EGFVKESLDRI 252
IAQ+ AQ G V + D + + ++S+QA L ++A K GK + ++ +L +
Sbjct: 18 IAQIAAQVGIQVLLFDAKAGAAEQGRQSLQAMLEKLAAK------GKFTDEQLQSTLKNL 71
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
+ + AD++IEAI+E L+IKQ LF +L+ + P TILATNTSS++V AI S +
Sbjct: 72 IVIEDIAKIAEADVVIEAIIENLEIKQQLFKQLESIVPAETILATNTSSLAVTAIASNCE 131
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
++ G HFFNPVP+M+++EVI + + K +G + KDTPGF+VN
Sbjct: 132 HPERVAGFHFFNPVPLMKIVEVIPGISTKSSVVETLTSLAKRMGHLGVVAKDTPGFIVNH 191
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
Y EAL++ G A+ EDID L+ GAGF MGPF L D
Sbjct: 192 GGRAYGTEALKILGEGVASFEDIDHILRDGAGFRMGPFELLD 233
Score = 39.1 bits (87), Expect = 0.11
Identities = 22/61 (36%), Positives = 32/61 (52%)
Frame = +1
Query: 556 SVGKTCITCKDTPGFVVNRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLA 735
+V T IT ++ GFV R++ + +G A+ EDID +KLG G+P GP
Sbjct: 429 AVDATLIT--ESTGFVAQRVVAMVINLGCDIAMQGIASPEDIDNAVKLGLGYPYGPISWG 486
Query: 736 D 738
D
Sbjct: 487 D 487
>UniRef50_A0RUN1 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase; n=4; Crenarchaeota|Rep: 3-hydroxyacyl-CoA
dehydrogenase/enoyl-CoA hydratase - Cenarchaeum
symbiosum
Length = 365
Score = 163 bits (395), Expect = 5e-39
Identities = 87/225 (38%), Positives = 138/225 (61%), Gaps = 3/225 (1%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKES-LDRI 252
IAQV+A +G V + D+E L+ A + I+ +L ++A K G+I K+ L+RI
Sbjct: 5 IAQVSAASGYEVVLRDIEQRFLDSAMEKIRWSLDKMASK------GRITAEEKDGILNRI 58
Query: 253 KISTKVEDSVN-ADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGI 429
+ + +++ ADL+IEA+ E +D+K+ ++ +LD APE A+NTS++ + I
Sbjct: 59 RPVVALGEALEGADLVIEAVPEVMDLKRKVYAELDAAAPEGAAFASNTSTLPITEIAQAT 118
Query: 430 KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITC-KDTPGFVV 606
R ++F G+HFFNP +M+L+EVI + S++T + +E+ +S+GK + C KD PGF+V
Sbjct: 119 SRPERFIGIHFFNPPQLMKLVEVIPGEGTSDETTRMTLEYVESLGKQAVLCRKDVPGFIV 178
Query: 607 NRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLADY 741
NR+ P EA +R A+ E ID +K G GFPMG F LAD+
Sbjct: 179 NRLFIPMVHEACHAMDRTGASMEQIDSAVKFGLGFPMGIFELADF 223
>UniRef50_P76083 Cluster: Probable 3-hydroxybutyryl-CoA
dehydrogenase; n=8; Enterobacteriaceae|Rep: Probable
3-hydroxybutyryl-CoA dehydrogenase - Escherichia coli
(strain K12)
Length = 475
Score = 163 bits (395), Expect = 5e-39
Identities = 93/223 (41%), Positives = 127/223 (56%), Gaps = 2/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLG-RVAKKLYKDDPGKIEGFVKE-SLDR 249
IA+V A G V + D+ E L +A I A L RV + GK+ E +L R
Sbjct: 20 IAEVAASHGHQVLLYDISAEALTRAIDGIHARLNSRVTR-------GKLTAETCERTLKR 72
Query: 250 IKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGI 429
+ T + ADL+IEA E+L++K+ LF +L ++ P T+L TNTSSIS+ AI + I
Sbjct: 73 LIPVTDIHALAAADLVIEAASERLEVKKALFAQLAEVCPPQTLLTTNTSSISITAIAAEI 132
Query: 430 KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVN 609
K ++ GLHFFNP PVM+L+EV+ + + + + E S GK + C TPGF+VN
Sbjct: 133 KNPERVAGLHFFNPAPVMKLVEVVSGLATAAEVVEQLCELTLSWGKQPVRCHSTPGFIVN 192
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
R+ PY +EA R E A E ID L+ GAGFPMGP L D
Sbjct: 193 RVARPYYSEAWRALEEQVAAPEVIDAALRDGAGFPMGPLELTD 235
Score = 46.0 bits (104), Expect = 0.001
Identities = 20/54 (37%), Positives = 32/54 (59%)
Frame = +1
Query: 562 GKTCITCKDTPGFVVNRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGP 723
GKT + D PG ++ R + EAL ++G A+++DID ++LG +P GP
Sbjct: 376 GKTVLQIADYPGMLIWRTVAMIINEALDALQKGVASEQDIDTAMRLGVNYPYGP 429
>UniRef50_A2TU34 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4;
Flavobacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Dokdonia donghaensis MED134
Length = 394
Score = 161 bits (392), Expect = 1e-38
Identities = 87/223 (39%), Positives = 134/223 (60%), Gaps = 1/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLD-RI 252
IAQV A AG V + D+ E L+KA+++++ L R+ +K G+I+ K+ + I
Sbjct: 17 IAQVAATAGCAVKLFDVNQEALDKAKEALEKVLKRLIEK------GRIDASEKDRIQANI 70
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
T +++ NADL IEAIVE L++K+ +F +L+ + I+A+NTSS+S+ +I + ++
Sbjct: 71 TYVTTLKELANADLTIEAIVENLEVKKKVFQELETYVSDTAIIASNTSSLSIASIAASLQ 130
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
++ G+HFFNP P+M+L+EVI + S++ + K KDTPGF+VNR
Sbjct: 131 NPERCIGIHFFNPAPLMKLVEVIPAVQTSQNVLDTCVAEITRWKKVVAIAKDTPGFIVNR 190
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLADY 741
+ P+ EALRMYE G A ID +K GF MGPF L D+
Sbjct: 191 VARPFYGEALRMYEEGVANFATIDAAMKSVGGFRMGPFELMDF 233
>UniRef50_Q11E57 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=1; Mesorhizobium sp. BNC1|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Mesorhizobium sp. (strain BNC1)
Length = 485
Score = 161 bits (391), Expect = 2e-38
Identities = 93/223 (41%), Positives = 131/223 (58%), Gaps = 2/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYK-DDPGKIEGF-VKESLDR 249
IAQV A AG V + D+ A + + L R AK+L GK+E +E + R
Sbjct: 23 IAQVAAAAGHKVLLFDV-------ASGAAASGLERTAKELATLVKRGKMEQKRAEEIIGR 75
Query: 250 IKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGI 429
I I+ K+ED A L +EAIVE+LD+KQ +F +L+ + E ILATNTSSIS+ AIG+ +
Sbjct: 76 ITIAEKLEDLAPAALTVEAIVERLDVKQKVFAQLEAILAEDAILATNTSSISITAIGAAL 135
Query: 430 KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVN 609
KR ++ G+HFFNP P+M+L+EV+ S + Q ++ GKT + K TPGF+VN
Sbjct: 136 KRPERLVGMHFFNPAPIMKLVEVVSGLATSPEVAQITHATARAWGKTAVHVKSTPGFIVN 195
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
R+ + E LR+ E G A +D ++ G GF MG F L D
Sbjct: 196 RVARAFYGEPLRLAEEGMADIATLDALMREGGGFRMGAFQLMD 238
Score = 40.3 bits (90), Expect = 0.049
Identities = 20/58 (34%), Positives = 28/58 (48%)
Frame = +1
Query: 562 GKTCITCKDTPGFVVNRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLA 735
G + D PG VV R L + EA +G A +E ID+ ++ G +P GP A
Sbjct: 382 GYSATELPDRPGLVVMRTLALIANEAFEAVLQGVADEESIDLAMRFGVNYPRGPIEWA 439
>UniRef50_A6ERZ1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
unidentified eubacterium SCB49|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - unidentified eubacterium SCB49
Length = 403
Score = 159 bits (386), Expect = 7e-38
Identities = 87/222 (39%), Positives = 132/222 (59%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IAQV A AG V + DL L+KA+ S++ + R+ +K + K ++E++ +
Sbjct: 32 IAQVAATAGCTVKLFDLNQAALDKAKASLEKIMTRLVEKGRVTEEEKAR--IQENISYVN 89
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
++ DS DL IEAI+E L IK+ +F +L+ + I+A+NTSS+S+ +I S +++
Sbjct: 90 ALKELADS---DLTIEAIIEDLGIKKKVFQELESYVSDSCIIASNTSSLSIASIASSLQK 146
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRI 615
++ G+HFFNP P+M+L+EVI + S+ + E KS K KDTPGF+VNR+
Sbjct: 147 PERCVGIHFFNPAPLMKLVEVIPAIQTSDAVLKISEETIKSWKKVVAVAKDTPGFIVNRV 206
Query: 616 LXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLADY 741
P+ EALR+YE G A ID +K GF MGPF L D+
Sbjct: 207 ARPFYGEALRIYEEGMADFATIDFAMKSLGGFRMGPFELMDF 248
>UniRef50_O30218 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 661
Score = 158 bits (383), Expect = 2e-37
Identities = 83/223 (37%), Positives = 136/223 (60%), Gaps = 2/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLY-KDDPGKIEGFVKESLDRI 252
IA+V A G NV ++D+ + L +A + I+ L + ++ Y +DP K+ ++ + D I
Sbjct: 21 IAEVVAIHGFNVKLMDVSEDQLKRAMEKIEEGLRKSYERGYISEDPEKVLKRIEATADLI 80
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
+++ +ADL+IEAI E D+K+ +F+++++ P+HTI ATNTSS+S+ + K
Sbjct: 81 EVAK------DADLVIEAIPEIFDLKKKVFSEIEQYCPDHTIFATNTSSLSITKLAEATK 134
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCI-TCKDTPGFVVN 609
R +KF G+HFFNP +++LLE++ + SE+T + + ++ + + + I KD PGF+VN
Sbjct: 135 RPEKFIGMHFFNPPKILKLLEIVWGEKTSEETIRIVEDFARKIDRIIIHVRKDVPGFIVN 194
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
RI S EA E G+ T E+ID +K G PMG F L D
Sbjct: 195 RIFVTMSNEASWAVEMGEGTIEEIDSAVKYRLGLPMGLFELHD 237
Score = 41.9 bits (94), Expect = 0.016
Identities = 27/93 (29%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
Frame = +1
Query: 463 FNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTC-ITCKDTPGFVVNRILXPYSAEA 639
+ P P+ L K+ H + T + +W S GKT + + F + R++ P EA
Sbjct: 262 YRPSPLFERL--FKAGHYGKKTGKGFYDW--SEGKTNEVPLRAGANFDLLRLVAPAVNEA 317
Query: 640 LRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+ E+G A+ E+ID+ + G +P G +AD
Sbjct: 318 AWLIEKGVASAEEIDLAVLHGLNYPRGLLRMAD 350
>UniRef50_Q6KYW3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Picrophilus torridus|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Picrophilus torridus
Length = 273
Score = 157 bits (380), Expect = 4e-37
Identities = 81/222 (36%), Positives = 141/222 (63%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IA+V A V + D+ +ILN +K I+A+L + +K G+I+ V++ L++I
Sbjct: 15 IAEVFALNNHEVLLSDVSNDILNNGRKKIEASLEKFKEK------GRIKS-VEDVLEKIS 67
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
++T + ++ +DL IEA++E++D+K+D+ +++ +I+ATNTSSIS+ + ++
Sbjct: 68 MNTDI-NAQESDLYIEAVLERIDVKRDVLSRIRS----DSIIATNTSSISITYLSKFVRN 122
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRI 615
+KF G+HFFNP P+M L+E+++ + S++T + +++ +S+GKT + D PGFV NR+
Sbjct: 123 PEKFIGMHFFNPPPIMSLIEIVRGNSTSDETTKRIVDISRSLGKTPVEVNDFPGFVSNRV 182
Query: 616 LXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLADY 741
L EA+ YE A+ E ID +KLG PMGP L+D+
Sbjct: 183 LMAMLREAIIAYEENVASAEGIDTVMKLGMNHPMGPLELSDF 224
>UniRef50_A0LSM1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5;
Actinomycetales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Length = 301
Score = 156 bits (379), Expect = 5e-37
Identities = 84/223 (37%), Positives = 134/223 (60%), Gaps = 2/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIE-GFVKESLDRI 252
IAQV A AG V + D+E L++A +I +L R+A+K GK+ V+ + RI
Sbjct: 22 IAQVAAVAGYAVRLHDIEESALHRALTTIDESLHRLARK------GKLSTSDVEAAKARI 75
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
+ ++ D ++D+++EA+ E+LD+K+ +F +L + + +LA+NT++I + I SG+
Sbjct: 76 TTTRRLADLADSDVVVEAVYEELDVKRVVFAELAAIVRPNVLLASNTTAIPITHIASGVS 135
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITC-KDTPGFVVN 609
+ G+HFF+PVPVM+L E+++ +DT + +S+GKTCI +D GFV +
Sbjct: 136 GPQRVVGMHFFSPVPVMQLCEIVRGLQTDDDTVARARRFAESLGKTCIVVNRDVAGFVTS 195
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
R+L + EALR+ E G AT EDID +LG G MGP D
Sbjct: 196 RLLVAFVNEALRLVESGIATPEDIDTACRLGFGHAMGPLATLD 238
>UniRef50_Q47M90 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5;
root|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Thermobifida fusca (strain YX)
Length = 398
Score = 155 bits (377), Expect = 8e-37
Identities = 89/223 (39%), Positives = 129/223 (57%), Gaps = 2/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGR-VAK-KLYKDDPGKIEGFVKESLDR 249
I +V A+AG VT V+++ L + + ++ +L + VAK KL +D+ I G R
Sbjct: 20 IVEVFARAGFTVTGVEIDDAALERGRTHLEKSLAKAVAKGKLTEDEQRAILG-------R 72
Query: 250 IKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGI 429
+ +T +D +A L +EA+ E+LDIK+ +F LD++ P ILATNTSS+SV I +
Sbjct: 73 VTFTTSRDDLADAHLAVEAVPERLDIKRSVFADLDRILPPAAILATNTSSLSVTEIAALT 132
Query: 430 KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVN 609
R K GLHFFNP PVMRL+E++ + + + +GKT + D GFV N
Sbjct: 133 SRPGKVIGLHFFNPAPVMRLVEIVTTVVTEPHVRETATQVVTRLGKTPVAVGDRAGFVAN 192
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+L PY A+ +YE+G AT+E ID + AGFPMGP L D
Sbjct: 193 ALLVPYLNHAVAVYEQGLATREQIDAAITSAAGFPMGPLTLMD 235
Score = 39.1 bits (87), Expect = 0.11
Identities = 19/53 (35%), Positives = 30/53 (56%), Gaps = 2/53 (3%)
Frame = +1
Query: 586 DTPGFV--VNRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
D PG + + +L P+ +A RM G AT +D+D ++LG G+P G + D
Sbjct: 305 DGPGQISLADLLLVPHLNDAARMIGDGYATADDVDTAMRLGCGYPKGLAAMLD 357
>UniRef50_Q397D0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=31;
Proteobacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 518
Score = 155 bits (376), Expect = 1e-36
Identities = 84/222 (37%), Positives = 125/222 (56%), Gaps = 1/222 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLD-RI 252
IAQV A AG V + DL +KA I+A R+A+K G++E ++ RI
Sbjct: 32 IAQVAAAAGHTVLLYDLNEAACDKALAGIRAQFARLAEK------GRLEPAQADAAGARI 85
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
+ ++ D A LI+EA E+LD+K+++F L++ + +LATNTSSIS+ +I +G++
Sbjct: 86 RAVRELADFAGAALIVEAAAERLDVKREIFATLERHVDDACLLATNTSSISITSIAAGLR 145
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
+ GLHFFNP P+M L+EV+ + + Q + + GK + K TPGF+VNR
Sbjct: 146 VPQRVAGLHFFNPAPLMALVEVVSGLATAPEVAQVLYATAAAWGKRPVMAKSTPGFIVNR 205
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+ PY AEALR+ ID ++ GF MGPF L D
Sbjct: 206 VARPYYAEALRVLNEQGGAPASIDAVMREAGGFRMGPFELMD 247
Score = 38.7 bits (86), Expect = 0.15
Identities = 20/84 (23%), Positives = 37/84 (44%)
Frame = +1
Query: 487 LLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRILXPYSAEALRMYERGDA 666
L+ + ++ S+ Y + + G + D PG V R + + EA +G
Sbjct: 394 LVALTRALQCSDAAYADAVGQFQQAGFRVVGVADVPGMVAMRTVAMLANEAADTVNQGVC 453
Query: 667 TKEDIDIGLKLGAGFPMGPFXLAD 738
+ D+D+ ++ G +P GP AD
Sbjct: 454 SPADLDLAMEKGVNYPCGPLAWAD 477
>UniRef50_Q39NP5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=54;
cellular organisms|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 284
Score = 155 bits (375), Expect = 1e-36
Identities = 85/222 (38%), Positives = 131/222 (59%), Gaps = 1/222 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKES-LDRI 252
IAQ A AG NV ++D+ L K +++ +L R+ K K++ +++ L RI
Sbjct: 18 IAQTAAVAGLNVVMIDVSDAALEKGIATLKGSLDRLVSK------DKLDAATRDAALARI 71
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
ST AD++IEA E +++K + +++ +A I+ATNTSSIS+ A+ + +
Sbjct: 72 TTSTDYAKLAAADIVIEAATENVELKGRILKQIEAVARAEAIIATNTSSISITALAAPLA 131
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
+F G+HFFNPVP+M L+E+I+ S+ T A+ E + K+ I +++PGFVVNR
Sbjct: 132 DPARFVGMHFFNPVPLMPLVEIIRGLQTSDATASAVRELTERFDKSPIGVRNSPGFVVNR 191
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
IL P EA + G A+ E+ID G+KLGA P+GP LAD
Sbjct: 192 ILVPMINEAFFVLAEGIASAEEIDAGMKLGANHPIGPLALAD 233
>UniRef50_A3YFA8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Marinomonas sp. MED121|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Marinomonas sp. MED121
Length = 545
Score = 155 bits (375), Expect = 1e-36
Identities = 100/225 (44%), Positives = 134/225 (59%), Gaps = 4/225 (1%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IAQV +QAG V + D E +A++SI L KK+ K + E + + I
Sbjct: 29 IAQVASQAGHKVFLYDQNEEASFRAKESISLLLN---KKVAKGTITR-EHYDTCIANIIP 84
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
+ + +++ +ADLIIEAIVE L+IKQ LF L+ + ILA+NTSSIS+ AI S +K
Sbjct: 85 LHS-LDELKSADLIIEAIVETLEIKQSLFRALELICKPECILASNTSSISITAIASCLKY 143
Query: 436 KDKFGGLHFFNPVPVMRLLEVIK---SDH-ISEDTYQAMMEWGKSVGKTCITCKDTPGFV 603
++F GLHFFNP PVM L+EVI SD I++ Y + WGK+ KT K TPGF+
Sbjct: 144 PERFLGLHFFNPAPVMPLVEVISGLASDQLIAKQLYDTCLLWGKTPVKT----KSTPGFI 199
Query: 604 VNRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
VNR+ P+ AEALR+YE A + ID +K F MGPF L D
Sbjct: 200 VNRVARPFYAEALRIYEEQGAGIQQIDRLMKTAGQFRMGPFELMD 244
Score = 41.9 bits (94), Expect = 0.016
Identities = 23/69 (33%), Positives = 33/69 (47%)
Frame = +1
Query: 517 SEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRILXPYSAEALRMYERGDATKEDIDIGLK 696
S Q M K + I +D PG +V R L + EA + +G A+ +DIDI +
Sbjct: 432 SNQAIQDAMTLFKLIEIDLIALEDIPGLIVMRTLAMLTNEAAQTCMQGIASAKDIDIAMC 491
Query: 697 LGAGFPMGP 723
G +P GP
Sbjct: 492 YGVNYPQGP 500
>UniRef50_Q2J6P6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=10;
Actinomycetales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Frankia sp. (strain CcI3)
Length = 624
Score = 153 bits (371), Expect = 4e-36
Identities = 80/222 (36%), Positives = 130/222 (58%), Gaps = 1/222 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKES-LDRI 252
IA+V A+AG V + + + L +++ ++ +L R + GK++ +E+ L R+
Sbjct: 53 IAEVLAKAGLEVVGIARDADALARSRARVEHSLDRAGRH------GKLDDATREAVLARM 106
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
++ T++ + +L+IEAI E++ KQ LF +LD++ P T+ TNTSS+SV + +G
Sbjct: 107 RLGTELAAVADCELVIEAIDERMSAKQALFARLDEICPPATVFLTNTSSLSVTELAAGTA 166
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
R ++ G H+FNP PVMRL+EV+++ ++ VGKT + +D GF+VN
Sbjct: 167 RPERVLGTHWFNPAPVMRLVEVVRTVVTDPTVLAGVIGLVNDVGKTAVVAEDRAGFIVNA 226
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+L Y A+RM E A +EDID ++LG G PMGP L D
Sbjct: 227 LLFGYLNNAVRMLEARYAAREDIDAAMRLGCGHPMGPLALLD 268
Score = 134 bits (325), Expect = 2e-30
Identities = 71/221 (32%), Positives = 122/221 (55%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IA+V A++G +V + L I+++L + D ++ +L R++
Sbjct: 357 IAEVLARSGHDVLLRARSERTLAATLAKIESSLAASVARGRLSDADRLA-----ALARVR 411
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
+T + + + +L++EA+VE L +K++LF LDK+A +LAT TSS+ V R
Sbjct: 412 GTTDLGELGHCELLLEAVVEDLAVKRELFADLDKIAAPGAVLATTTSSLPVIECAMATSR 471
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRI 615
G+H+FNP P M+L+EV+ + +D ++ ++ G+ + C D GF+VN +
Sbjct: 472 PRDVIGMHWFNPAPAMKLIEVVPTVLTGDDVTATVLALSRAAGRHPVLCADRAGFIVNAL 531
Query: 616 LXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
L PY +A++M + AT ED+D + +G G P+GPF LAD
Sbjct: 532 LFPYLNDAVKMLQAHYATIEDVDTAMTVGCGHPLGPFALAD 572
>UniRef50_Q1ATL4 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Rubrobacter xylanophilus DSM 9941|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Rubrobacter
xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 287
Score = 153 bits (370), Expect = 6e-36
Identities = 82/223 (36%), Positives = 128/223 (57%), Gaps = 2/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKI-EGFVKESLDRI 252
I QV A+AG V D E L KA++ +++ L A++ G + E + +L R+
Sbjct: 17 IVQVAARAGYRVVACDASEEALGKARRYVRSGLESFARR------GALSEEEAEAALGRV 70
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
+ +T +E+ ++ +IEAIVE++ K++ F LD L P +L TNTSSIS+ + S
Sbjct: 71 RWTTAMEELAGSEAVIEAIVERVGPKKEAFAALDALLPPDALLLTNTSSISITELASATG 130
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGK-TCITCKDTPGFVVN 609
R ++ G HFF P P+ +EV++ + S++T + + S GK + KD PGF N
Sbjct: 131 RPERVCGAHFFTPPPLREAVEVVRGEQTSDETVERVRRLLSSFGKLPVVVRKDVPGFAAN 190
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
R+L P EA R+ E G A++E++D+ G GFP+GPF LAD
Sbjct: 191 RLLMPVLLEAARLVEEGVASREEVDLLATRGLGFPLGPFQLAD 233
>UniRef50_Q5KYB5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=6;
Bacillaceae|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Geobacillus kaustophilus
Length = 287
Score = 152 bits (369), Expect = 8e-36
Identities = 90/223 (40%), Positives = 125/223 (56%), Gaps = 2/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQA--NLGRVAKKLYKDDPGKIEGFVKESLDR 249
IA V A G T+VD++ E L AQK I + G KL + + E + SLD
Sbjct: 17 IAYVGAVGGFQTTLVDIKQEQLESAQKEIASIFEQGVARGKLTDSERQEAEARLSYSLD- 75
Query: 250 IKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGI 429
++ V D ADL+IEA+ EKL++K+ +F +D AP ATNTS++S IGS
Sbjct: 76 --LAAAVRD---ADLVIEAVPEKLELKKQVFETIDAHAPASCYFATNTSTMSPTEIGSFT 130
Query: 430 KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVN 609
KR ++ +HFFNPV M+L+E+I+ S++T Q E + +GK + + PGFV +
Sbjct: 131 KRPERVIAMHFFNPVHKMKLVEIIRGLETSDETAQVAKEAAERMGKETVVVNEFPGFVTS 190
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
RI EA M + G T E+ID +KLG FPMGPF LAD
Sbjct: 191 RISALVGNEAFYMLQEGVGTPEEIDKAIKLGLNFPMGPFELAD 233
>UniRef50_A0QZR0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Mycobacterium smegmatis str. MC2 155|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Mycobacterium
smegmatis (strain ATCC 700084 / mc(2)155)
Length = 296
Score = 150 bits (364), Expect = 3e-35
Identities = 76/222 (34%), Positives = 125/222 (56%), Gaps = 1/222 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESL-DRI 252
IA V A+AG + D+ L + ++ + + GK++ ++ D +
Sbjct: 24 IATVMARAGHRTILYDINEANLERGIDTVHGFFDKSVRL------GKLDATAGQAAKDSL 77
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
ST+++D D+++EA+ E L +K++ F +LD + P T+ TNTS++SV I SG +
Sbjct: 78 SGSTELKDLAPCDVVVEAVFEDLSLKKETFGRLDDIVPPTTLFHTNTSTLSVTGIASGSR 137
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
+++ G H+ NP P+M+L+EV H ++ ++A +E+ S+GKT + KD PGF+VNR
Sbjct: 138 LRERVVGTHYCNPAPLMKLVEVANGRHTADWAHKATLEFLASLGKTSVVTKDRPGFIVNR 197
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
L P+ + E G ATKE+ID + G PMGPF L D
Sbjct: 198 FLIPWENSCIEALEAGVATKEEIDTAVLGALGHPMGPFRLLD 239
>UniRef50_Q5V357 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
Halobacteriaceae|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Haloarcula marismortui (Halobacterium marismortui)
Length = 669
Score = 150 bits (363), Expect = 4e-35
Identities = 83/223 (37%), Positives = 135/223 (60%), Gaps = 2/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
I +V A AG +V + D++ E + +I+ +L ++A++ D + E +LDR+
Sbjct: 36 ITEVAALAGYDVRMRDIKDEFVEDGYDNIEWSLNKLAER---DQLTQEEA--DAALDRVT 90
Query: 256 ISTKVEDSVN-ADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
VE++V+ D++IEA+ EK++IK+D++ ++++ APE+ I ATNTSS+S+ + +
Sbjct: 91 PLVDVEEAVSDVDVVIEAVPEKMEIKKDVYTEVEEHAPENAIFATNTSSLSITELSEVTE 150
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITC-KDTPGFVVN 609
R ++F G+HFFNP M+L+EVI H +DT +A+ + GKT + KD+PGF+VN
Sbjct: 151 RPEQFCGMHFFNPPVRMQLVEVISGAHSGDDTLEAIEALAEDFGKTPVRVRKDSPGFIVN 210
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
RIL P EA + AT ++D K G PMG F L+D
Sbjct: 211 RILVPLMNEAAWLVHDDAATIAEVDSTTKFDMGLPMGSFELSD 253
Score = 34.3 bits (75), Expect = 3.2
Identities = 17/46 (36%), Positives = 26/46 (56%)
Frame = +1
Query: 601 VVNRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
V +R++ + E ++ E A DID ++LG GFP GP +AD
Sbjct: 317 VEHRLVAVMANEVGKLVENDVAPVADIDQAVQLGGGFPDGPAKIAD 362
>UniRef50_Q45223 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=92;
cellular organisms|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Bradyrhizobium japonicum
Length = 293
Score = 150 bits (363), Expect = 4e-35
Identities = 81/222 (36%), Positives = 124/222 (55%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IA V A AG +V + D+ + L +I NL R K + K + +L RI
Sbjct: 20 IAHVAALAGFDVVLNDVSADRLKSGMATINGNLARQVSKKVVTEEAKTK-----ALSRIV 74
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
+ K++D + DL+IE VEK ++K+ +F++L + I+A++TSSIS+ + + R
Sbjct: 75 AAEKLDDLADCDLVIETAVEKEEVKRKIFHELCAVLKPEAIVASDTSSISITRLAAATDR 134
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRI 615
++F G+HF NPVP+M L+E+I+ + T++A E+ +GK +D P F+VNRI
Sbjct: 135 PERFIGIHFMNPVPLMELVELIRGIATDDATFEASKEFVAKLGKQVAVSEDFPAFIVNRI 194
Query: 616 LXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLADY 741
L P EA+ G E ID +KLGA PMGP LAD+
Sbjct: 195 LLPMINEAIYTLYEGVGNVEAIDAAMKLGAHHPMGPLELADF 236
>UniRef50_A0IJE2 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=5; Gammaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Serratia proteamaculans 568
Length = 506
Score = 149 bits (362), Expect = 5e-35
Identities = 82/223 (36%), Positives = 123/223 (55%), Gaps = 2/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKL-YKDDPGKIEGFVKESL-DR 249
IAQV A AG V + D+ +A LG +A++L + GK + E+L R
Sbjct: 22 IAQVAAAAGHQVQLFDIAASAARQA-------LGALAQRLRQRVAAGKADATTTEALLAR 74
Query: 250 IKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGI 429
I+ + + ++ L+IEA+ EKL IKQ LF +L+ L T+ A+NTSS+S+ AI +
Sbjct: 75 IQPAESLNSLADSGLVIEAVAEKLAIKQSLFRELEALCSPATLFASNTSSLSITAIAGAL 134
Query: 430 KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVN 609
+ + GLHFFNP P+M+L+E++ S +T + + GK + C+ TPGF+VN
Sbjct: 135 QHPQRLAGLHFFNPAPLMKLVEIVSGLDTSTETVATLQRLTRQWGKQSVLCRSTPGFIVN 194
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
R+ P+ AEALR E A +D ++ GF MGP L D
Sbjct: 195 RVARPFYAEALRALEEQVADAATLDAVIRDAGGFVMGPLQLTD 237
Score = 47.6 bits (108), Expect = 3e-04
Identities = 25/70 (35%), Positives = 39/70 (55%), Gaps = 1/70 (1%)
Frame = +1
Query: 517 SEDTYQA-MMEWGKSVGKTCITCKDTPGFVVNRILXPYSAEALRMYERGDATKEDIDIGL 693
++D + A +M +S+GK I D PG +V R L + EAL + +G A+ ED D +
Sbjct: 391 NDDRHNATIMRLLQSLGKKVIALPDYPGLLVMRTLAMLANEALDVVNKGVASAEDTDHAM 450
Query: 694 KLGAGFPMGP 723
+ G +P GP
Sbjct: 451 RYGVNYPRGP 460
>UniRef50_Q9YBW6 Cluster: 3-hydroxyacyl-CoA
dehydrogenase/3-hydroxybutyryl-CoA dehydratase; n=19;
cellular organisms|Rep: 3-hydroxyacyl-CoA
dehydrogenase/3-hydroxybutyryl-CoA dehydratase -
Aeropyrum pernix
Length = 669
Score = 149 bits (361), Expect = 7e-35
Identities = 93/233 (39%), Positives = 129/233 (55%), Gaps = 11/233 (4%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IA++ A AG V + D+ +ILN A + I+ +L ++A+K G+I V+ + RI
Sbjct: 20 IAELAAIAGFKVYLADINIDILNNALQRIRWSLEKLAEK------GRIRESVETVMSRIT 73
Query: 256 ISTKVEDSV----------NADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSIS 405
V D +D +IEAI EKL++KQ LF DK A E ILA+NTSS+
Sbjct: 74 PIVSVRDGEYSEDLAKALSESDFMIEAIPEKLELKQQLFAFADKHAKETAILASNTSSLP 133
Query: 406 VNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGK-TCITC 582
+ I + R +K G+HFFNP +M L+EV+K + SE+T A ++ K +GK T +
Sbjct: 134 ITEIAAATSRPEKVVGMHFFNPPVLMPLVEVVKGEKTSEETVAATVDLAKKMGKQTVVVK 193
Query: 583 KDTPGFVVNRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLADY 741
KD PGF+VNRIL A + ERG T +D K G PMG F LADY
Sbjct: 194 KDVPGFIVNRILGRLMESACLLVERGGYTVVQVDATAKYLLGLPMGVFELADY 246
Score = 35.1 bits (77), Expect = 1.8
Identities = 17/35 (48%), Positives = 21/35 (60%)
Frame = +1
Query: 634 EALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
EA + AT+EDID +KLG G+P G F AD
Sbjct: 322 EAAWLLREDVATREDIDKAVKLGLGWPKGVFEYAD 356
>UniRef50_Q11E55 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=1; Mesorhizobium sp. BNC1|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Mesorhizobium sp. (strain BNC1)
Length = 506
Score = 149 bits (360), Expect = 9e-35
Identities = 82/221 (37%), Positives = 125/221 (56%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IA V A+AG D E L ++SI A K + K + +L R+
Sbjct: 20 IAMVAARAGFQTICFDQNGEAL---RRSIGAAEDFFRKSVEKGRMSPDD--CDNALSRMT 74
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
ST ++D + DLIIEAI E L+ KQ LF L+++ TILA+NTS++S+ I SG R
Sbjct: 75 TSTNLKDLADCDLIIEAIFENLEAKQQLFRSLNEICKPETILASNTSTLSITQIASGCGR 134
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRI 615
+D+ G HF P +M+L+E+ + + S+ + A + W K+ G+ + +D PGF++N +
Sbjct: 135 EDRVVGTHFCLPAQLMKLVEMSRGINTSDGVFSAALAWTKAAGQLPVETQDKPGFILNAL 194
Query: 616 LXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
L P++ + LR E G AT EDID+ ++ G G+ MGP L D
Sbjct: 195 LVPFNNDVLRAIEAGLATAEDIDLAIRSGLGYKMGPCTLLD 235
Score = 58.0 bits (134), Expect = 2e-07
Identities = 26/79 (32%), Positives = 44/79 (55%)
Frame = +1
Query: 487 LLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRILXPYSAEALRMYERGDA 666
L+E+++ + A + G + C D PG +V+R++ P +ALR+ + G A
Sbjct: 381 LVELVRQPRTDAEAIMAARAIFEDAGFDVVICADQPGRIVDRLVRPKYNDALRLLDEGLA 440
Query: 667 TKEDIDIGLKLGAGFPMGP 723
T ED+D+ +LG G+P GP
Sbjct: 441 TAEDMDMTCRLGLGYPEGP 459
>UniRef50_Q9XA30 Cluster: Putative 3-Hydroxyacyl-CoA dehydrogenase;
n=2; Streptomyces|Rep: Putative 3-Hydroxyacyl-CoA
dehydrogenase - Streptomyces coelicolor
Length = 504
Score = 147 bits (355), Expect = 4e-34
Identities = 82/222 (36%), Positives = 124/222 (55%), Gaps = 1/222 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLD-RI 252
IAQV AG V + D +A +I A L R+ +K ++ G +++ R+
Sbjct: 22 IAQVALVAGHPVRLYDAVDGRAREAADAIGARLDRLVEK------DRLTGAERDAARARL 75
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
+ + + + L++EA+VE+LD+KQ+LF L+ + + +LATNTSS+SV A+G ++
Sbjct: 76 VPAGTLGELADCALVVEAVVERLDVKQELFRALEDVVGDDCLLATNTSSLSVTAVGGALR 135
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
+F GLHFFNP P++ L+EV+ + E ++ GKT + C DTPGFVVNR
Sbjct: 136 VPGRFVGLHFFNPAPLLPLVEVVSGFATDPASATRAYETARAWGKTPVACADTPGFVVNR 195
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+ P+ AEAL YE A +D L+ GF MG F L D
Sbjct: 196 VARPFYAEALAAYEARAADPATVDAVLRESGGFRMGAFELTD 237
Score = 42.7 bits (96), Expect = 0.009
Identities = 19/58 (32%), Positives = 30/58 (51%)
Frame = +1
Query: 553 KSVGKTCITCKDTPGFVVNRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPF 726
+++GK D PG +V R + A +G A ED+D ++LG +P+GPF
Sbjct: 399 QALGKKVSVIGDIPGMIVARTVARIIDLAFDAVAKGVAAPEDVDTAMRLGVNYPLGPF 456
>UniRef50_A1SPQ6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3;
Actinomycetales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Nocardioides sp. (strain BAA-499 / JS614)
Length = 287
Score = 147 bits (355), Expect = 4e-34
Identities = 82/222 (36%), Positives = 123/222 (55%), Gaps = 1/222 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IA V A AG V + D++P +L +A + ++ + R +K + F E L
Sbjct: 16 IAMVCALAGHQVCLHDVDPAMLERADRELRDRMARQVEKGRRTADDVTAAF--ERLRVAD 73
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
+ +ADL+IEA+VE++++K +LF +LD+L P TILA+N+SS + + + R
Sbjct: 74 SLAAAAAAADADLVIEAVVERIEVKSELFAELDRLCPPATILASNSSSFVPSRLAAATGR 133
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITC-KDTPGFVVNR 612
D+ LHFFNP VM +EV+ S T + ++ +S+GK + K+ PGFV NR
Sbjct: 134 ADRVCNLHFFNPALVMACVEVVPGPETSGQTVASCVDLVESLGKVPVVLEKEIPGFVANR 193
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
IL EA+R+YE G A E ID + G+PMGPF L D
Sbjct: 194 ILNAVRDEAIRLYEGGYAGVEAIDTACRTALGYPMGPFELMD 235
>UniRef50_Q5UWD9 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
cellular organisms|Rep: 3-hydroxyacyl-CoA dehydrogenase
- Haloarcula marismortui (Halobacterium marismortui)
Length = 295
Score = 147 bits (355), Expect = 4e-34
Identities = 78/223 (34%), Positives = 133/223 (59%), Gaps = 2/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGR-VAKKLYKDDPGKIEGFVKESLDRI 252
IAQV+A AG +V++ D+E +I++ +I++NL +A++ E + ++DR+
Sbjct: 16 IAQVSAMAGHDVSLRDIEADIVDDGLTAIESNLEEGIAREKVT------ESTAEATIDRL 69
Query: 253 KISTKVEDSVN-ADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGI 429
K +T +E++V ADL++EA+ E++ IK + ++ T++A+NTSS+S+ I S +
Sbjct: 70 KGTTSLEEAVTGADLVVEAVPEEMAIKHETLTAVESHVDPATLIASNTSSLSLTEIASVL 129
Query: 430 KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVN 609
++ GLHFFNPV +M L+E++ ++ S +T E+ + KT + D PGF +
Sbjct: 130 DYPERAIGLHFFNPVHIMALVEIVVAEQTSAETIARAREFVNGIDKTPVEVADAPGFASS 189
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
R+ EA+RM + G AT +DID ++LG PMGP L D
Sbjct: 190 RLGVSLGVEAMRMVQEGVATPQDIDTAMELGYNHPMGPIELGD 232
>UniRef50_A5V4A1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Sphingomonas wittichii RW1|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Sphingomonas wittichii RW1
Length = 489
Score = 146 bits (353), Expect = 7e-34
Identities = 83/221 (37%), Positives = 120/221 (54%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IA V AQAG V ++D + L++ ++S+ +L + K+ D+ G +RI
Sbjct: 21 IALVAAQAGHAVRVIDTQDAALDRGRQSVARSLASLVKRGTIDEAG-----AAAIAERIG 75
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
ST V D+ A L IEAIVE++D+K LF L + ILA+NTSS+S+ A+ S +
Sbjct: 76 WSTDVADAAPAALAIEAIVERMDVKTGLFETLARHVAPGAILASNTSSLSIEAMASAVPG 135
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRI 615
++F GLHFFNPVP M+L+E+I S + + ++ K + +D PGF+VNR+
Sbjct: 136 PERFAGLHFFNPVPAMKLVELIPSSRTAPTVVDDLEALMRAWKKLPVRVRDVPGFIVNRV 195
Query: 616 LXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
PY AE G ID L+ GF MGP LAD
Sbjct: 196 ARPYYAEGFAALGEG-VDPATIDQALESAGGFRMGPLTLAD 235
>UniRef50_Q5V0V6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Halobacteriaceae|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Haloarcula marismortui (Halobacterium marismortui)
Length = 654
Score = 145 bits (351), Expect = 1e-33
Identities = 85/223 (38%), Positives = 130/223 (58%), Gaps = 2/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IA+V A AG +V + D++ I+ I+ +L ++A+K G+++ + R+
Sbjct: 23 IAEVAAIAGYDVVLRDIDAAIVEDGYDEIEWSLEKLAEK------GRLDEDPDDVAARVA 76
Query: 256 ISTKVEDSVN-ADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
+T +E +V+ ADL+IEA E+L +KQD+F +D AP +LATN+SS+S+ I + +
Sbjct: 77 TTTDLEAAVSDADLVIEAGPEQLSVKQDIFESVDAAAPADALLATNSSSLSITEIAAATE 136
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCI-TCKDTPGFVVN 609
R + GLHFFNP M L+EVI +++T Q E+ +S+GKT I KD GFVVN
Sbjct: 137 RPESVLGLHFFNPPVKMDLVEVIYGKATTDETAQRGYEFIESLGKTPIYVRKDVRGFVVN 196
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+L P+ +E M G+AT D + G+PMGPF L D
Sbjct: 197 SVLGPFMSEPAWMVSAGEATIRQADAAMVHERGYPMGPFELGD 239
Score = 43.6 bits (98), Expect = 0.005
Identities = 27/90 (30%), Positives = 46/90 (51%)
Frame = +1
Query: 469 PVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRILXPYSAEALRM 648
PVP + + E +++ ++ T + ++ G + +D+ GF R+ + EA ++
Sbjct: 256 PVPPI-MAEKVENGNLGRKTGEGYYDYDDGDGSDYVP-EDSEGFDHRRVEAVMANEAAKL 313
Query: 649 YERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
AT E ID G++LGAGFP G AD
Sbjct: 314 VGDDVATAEAIDTGMQLGAGFPEGTCRRAD 343
>UniRef50_Q8FUX6 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=4; Brucella|Rep: 3-hydroxyacyl-CoA
dehydrogenase family protein - Brucella suis
Length = 501
Score = 144 bits (350), Expect = 2e-33
Identities = 83/221 (37%), Positives = 123/221 (55%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IA+ A G +V + D ++ +KA + A R+ ++ + G + L+RI
Sbjct: 21 IAETMAAGGIDVLLFD---QMADKASAAKLALSHRLQSRVERGKLGADRA--AQILERIV 75
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
++++ V+ADL++EAIVE L +K+DL L+ + P ++ATNTSS+SV AI + K
Sbjct: 76 PVQQLDEIVSADLVVEAIVENLTVKKDLVAALEAILPRQAVIATNTSSLSVTAIAASAKY 135
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRI 615
++ G HFFNPVP+MR++EVIK + A+ E VG + DTPGF++N
Sbjct: 136 PERIAGFHFFNPVPLMRVVEVIKGALTGDAVVDALKELAVRVGHRPVNATDTPGFIINHA 195
Query: 616 LXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
Y EAL M + G A ID L+ AGF MGPF L D
Sbjct: 196 GRAYGTEALAMVKEGVADFATIDTILRDAAGFRMGPFELFD 236
Score = 37.9 bits (84), Expect = 0.26
Identities = 22/81 (27%), Positives = 34/81 (41%)
Frame = +1
Query: 496 VIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRILXPYSAEALRMYERGDATKE 675
++ S SE+ M G DT G V R+L A + ++ +
Sbjct: 378 LVASPASSENARAQAMALATIDGVNASIVNDTCGTVCQRVLAMIVNIAADIIQQNITCTD 437
Query: 676 DIDIGLKLGAGFPMGPFXLAD 738
D+D +KLG G+P+GP D
Sbjct: 438 DLDAAVKLGLGYPLGPLAWGD 458
>UniRef50_A0LPA1 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Syntrophobacter fumaroxidans MPOB|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
Length = 287
Score = 144 bits (350), Expect = 2e-33
Identities = 78/223 (34%), Positives = 131/223 (58%), Gaps = 2/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKES-LDRI 252
IAQ+ AQ G V I D+ E+ +KA+ I+ L + + + GK++ K++ L RI
Sbjct: 18 IAQLCAQQGFEVVIADISLELSDKAKARIEKGLRK------RVEQGKLDAAQKDAILSRI 71
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
+ + + + +IE+++E + IK+ +F +LD L+P TILATNT+S+S++A+ +
Sbjct: 72 QTAGDLGPAAVCRFVIESVIEDIAIKRKVFAELDNLSPPETILATNTTSLSISAMAEATR 131
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCK-DTPGFVVN 609
R ++ +HFFNP +M+L+E++ S +T +A E+ + +GK + CK + P +V+
Sbjct: 132 RPERVVQMHFFNPPVIMKLVEIMPGKKTSRETVEAAAEFARQLGKDPVVCKNEAPAGIVS 191
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
R+L EA + G A +DID +KLGA PMGP L D
Sbjct: 192 RVLGQLLNEATWLVASGVADPQDIDKAMKLGANHPMGPLELID 234
>UniRef50_Q8FX64 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=10; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase family protein - Brucella suis
Length = 509
Score = 144 bits (348), Expect = 3e-33
Identities = 83/222 (37%), Positives = 125/222 (56%), Gaps = 1/222 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGF-VKESLDRI 252
IAQ+ AQAG I D ++ + + L ++A+K GKI + ++ RI
Sbjct: 20 IAQIAAQAGLVTQIFDAREGAAAASRDRLASTLAKLAEK------GKISAEDAQTAVSRI 73
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
+I + +++ + DL++EAIVEKLD KQ LF +L+ + + ILATNTSS+SV +I +
Sbjct: 74 EICSSIQELADCDLVVEAIVEKLDAKQALFLELEAVVSGNCILATNTSSLSVTSIARVCR 133
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
++ G HFFNPVP+M+++EVI A++ K +G I KD PGF++N
Sbjct: 134 HPERVAGFHFFNPVPLMKVVEVIDGLTTDPAVGDALLVLAKRMGHHGIRAKDMPGFIINH 193
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
Y EAL+++ A + DID L+ AGF MGP L D
Sbjct: 194 AGRAYGTEALKIFGECVAPRGDIDRILRESAGFRMGPLELFD 235
Score = 43.2 bits (97), Expect = 0.007
Identities = 21/59 (35%), Positives = 30/59 (50%)
Frame = +1
Query: 562 GKTCITCKDTPGFVVNRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
G +D+ GFV R L A + ++G AT +DID ++LG G+P GP D
Sbjct: 404 GVNVTVIRDSVGFVAQRTLAAIVNLACDIAQQGIATADDIDQAVRLGLGYPQGPLAWGD 462
>UniRef50_Q12D24 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=5; Burkholderiales|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 511
Score = 144 bits (348), Expect = 3e-33
Identities = 85/222 (38%), Positives = 121/222 (54%), Gaps = 1/222 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGF-VKESLDRI 252
IAQV AQAG V + D +A+ + +L + K GK+ V ++L RI
Sbjct: 27 IAQVAAQAGHAVMLYDAREGAAAEAKTKLAKSLDALVAK------GKLTAQGVSQTLSRI 80
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
+ + + A L+IEAIVEKLD+K+ LF +L+ + +LATNTSSISV AI +G++
Sbjct: 81 EAIASLAAAAPARLVIEAIVEKLDVKRGLFQQLEAIVAADCVLATNTSSISVTAIANGLQ 140
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
+ G+HFFNPVP MRL+EV+ + + GK + + TPGF+VNR
Sbjct: 141 HPARLVGMHFFNPVPQMRLVEVVSGLQTDPAVAALIFDLAGVWGKVAVHARSTPGFIVNR 200
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
I P+ AE L + + AT +D L+ GF MGP L D
Sbjct: 201 IARPFYAETLALLQEQAATPAVLDACLR-AVGFRMGPCALMD 241
Score = 41.5 bits (93), Expect = 0.021
Identities = 23/64 (35%), Positives = 29/64 (45%)
Frame = +1
Query: 535 AMMEWGKSVGKTCITCKDTPGFVVNRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFP 714
A W +++G + D PG VV R L EA G T E D +KLG +P
Sbjct: 405 AAATWLQALGFSPQRIADVPGLVVARTLAMLINEAADAVLHGVCTPEGADAAMKLGVNYP 464
Query: 715 MGPF 726
GPF
Sbjct: 465 AGPF 468
>UniRef50_Q8YB80 Cluster: 3-HYDROXYBUTYRYL-COA DEHYDROGENASE; n=32;
Proteobacteria|Rep: 3-HYDROXYBUTYRYL-COA DEHYDROGENASE -
Brucella melitensis
Length = 565
Score = 143 bits (346), Expect = 5e-33
Identities = 86/223 (38%), Positives = 127/223 (56%), Gaps = 2/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYK-DDPGKIEGF-VKESLDR 249
IAQ+ AQAG L +I + + + A+L R+A L K + GKI + ++ R
Sbjct: 60 IAQIAAQAG-------LVTQIFDAREGAAAASLDRLASTLAKLAEKGKISAEDAQTAVSR 112
Query: 250 IKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGI 429
I+I + +++ + DL++EAIVEKLD KQ LF +L+ + + ILATNTSS+SV +I
Sbjct: 113 IEICSSIQELADCDLVVEAIVEKLDAKQALFLELEAVVSGNCILATNTSSLSVTSIARVC 172
Query: 430 KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVN 609
+ ++ G HFFNPVP+M+++EVI A++ K +G I KD PGF++N
Sbjct: 173 RHPERVAGFHFFNPVPLMKVVEVIDGLTTDPAVGDALLVLAKRMGHHGIRAKDMPGFIIN 232
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
Y EAL++ A + DID L+ AGF MGP L D
Sbjct: 233 HAGRAYGTEALKILGECVAPRGDIDRILRESAGFRMGPLELFD 275
Score = 41.5 bits (93), Expect = 0.021
Identities = 20/54 (37%), Positives = 29/54 (53%)
Frame = +1
Query: 562 GKTCITCKDTPGFVVNRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGP 723
G +D+ GFV R L A + ++G AT +DID ++LG G+P GP
Sbjct: 444 GVNVTVIRDSVGFVAQRTLAAIVNLACDIAQQGIATADDIDQAVRLGLGYPQGP 497
>UniRef50_Q9RUA4 Cluster: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA
isomerase/3-hydroxyacyl-CoA dehydrogenase; n=18;
Bacteria|Rep: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA
isomerase/3-hydroxyacyl-CoA dehydrogenase - Deinococcus
radiodurans
Length = 708
Score = 142 bits (344), Expect = 8e-33
Identities = 84/223 (37%), Positives = 124/223 (55%), Gaps = 2/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKK--LYKDDPGKIEGFVKESLDR 249
IA G VTIV+ E L++ I+ N AKK + +DD K G + +L
Sbjct: 322 IAMNFLNVGIPVTIVETSQEALDRGLGVIRKNYENTAKKGRMTQDDVEKRMGLLTPTL-- 379
Query: 250 IKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGI 429
K+ED AD+IIEA+ E +D+K+D+F +LDK+A ILA+NTS++ VN I S
Sbjct: 380 -----KMEDLAGADIIIEAVFENMDVKKDIFTRLDKIAKPGAILASNTSTLDVNEIASVT 434
Query: 430 KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVN 609
R ++ GLHFF+P VM+LLE++++D S+ + K + K + GFV N
Sbjct: 435 GRPEQVIGLHFFSPANVMKLLEIVRADKTSDSVLATSLALAKRIKKVGVVVGVCDGFVGN 494
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
R++ Y EA ++ E G A ED+D + G PMGPF ++D
Sbjct: 495 RMVHRYGDEARKIVEEG-ARPEDVDAAMN-ALGLPMGPFQMSD 535
>UniRef50_Q11TH9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=16;
Bacteroidetes|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)
Length = 298
Score = 142 bits (344), Expect = 8e-33
Identities = 90/224 (40%), Positives = 119/224 (53%), Gaps = 2/224 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESL-DRI 252
IA AQ G V + D LNKA I NL R K G I KE++ RI
Sbjct: 20 IAHSFAQFGFQVFLCDSNAAALNKAMLQISTNLERQISK------GIIPDSEKETIISRI 73
Query: 253 KISTKVEDSVNA-DLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGI 429
T +++ L++EA+ E L+IK DLF +LD P TILA+NTSSIS+ + S
Sbjct: 74 TPITDFKEAAKTVSLVVEAVPELLEIKADLFKELDMHCPPETILASNTSSISITTLASYT 133
Query: 430 KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVN 609
R +K G+HF NPVPVM+L+E+I S +T + + E + K + D PGF+ N
Sbjct: 134 SRPEKVIGMHFMNPVPVMQLVEIINGLLTSSETTRRIEEISTQLNKIPVQTADYPGFISN 193
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLADY 741
RIL P EA+ + A +ID +KLG PMGP LADY
Sbjct: 194 RILMPMINEAIYCVQERVAGIAEIDQIMKLGMAHPMGPLQLADY 237
>UniRef50_Q1GNH9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=7;
cellular organisms|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Sphingopyxis alaskensis (Sphingomonas
alaskensis)
Length = 288
Score = 142 bits (343), Expect = 1e-32
Identities = 80/224 (35%), Positives = 121/224 (54%), Gaps = 2/224 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVA--KKLYKDDPGKIEGFVKESLDR 249
IAQV+A AG +V + D++ + I LGR+ +K+ + D + + D
Sbjct: 15 IAQVSAGAGHDVLLADIDLARAEAGKAGIAKALGRLVAREKMAQSDADMLLARITPVADH 74
Query: 250 IKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGI 429
+ +DL+IEA E+ +IK+ +F + + ILA+NTSSI + +
Sbjct: 75 AAFAP-------SDLVIEAATEREEIKRAIFASVGEHLSATAILASNTSSIPITRLAQAA 127
Query: 430 KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVN 609
+F G+HFFNPVPVM L+E+I+ S+DT + +G+ +GK + D PGF+VN
Sbjct: 128 PDPARFIGVHFFNPVPVMGLIELIRGLATSDDTLATVEAYGRGLGKQIVHANDAPGFIVN 187
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLADY 741
R+L P EA+ G AT +DID G +LG PMGP LAD+
Sbjct: 188 RVLMPLINEAIFALGEGVATMQDIDAGCRLGLNHPMGPITLADF 231
>UniRef50_Q4J6T7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Archaea|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Sulfolobus acidocaldarius
Length = 657
Score = 142 bits (343), Expect = 1e-32
Identities = 80/224 (35%), Positives = 130/224 (58%), Gaps = 2/224 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVA-KKLYKDDPGKIEGFVKESLDRI 252
IA+V A AG NV + D+ +IL A + I+ +L ++ K+ K++P + L RI
Sbjct: 19 IAEVVAIAGFNVVLTDVNEDILRNALEKIRWSLEKLREKRQIKENPNTV-------LSRI 71
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
K + D + D IIEA +E+ D+K+ +F++LD++ + I ATNTS+I ++ +
Sbjct: 72 KTTVSFGDFSDVDFIIEAAIERSDVKRKIFSELDRVVKKDAIFATNTSTIPISYLAEVTG 131
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITC-KDTPGFVVN 609
R++KF GLHF NP +M L+E+I + +E+T + ++ K + K + KD PGF++N
Sbjct: 132 RQEKFIGLHFMNPPVLMPLVEIIMGNKTAEETLKTTIDLAKKINKDYVVVKKDVPGFLIN 191
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLADY 741
RI EA+ +Y+ G +KEDID + G PMG L D+
Sbjct: 192 RINGRTFPEAVLLYDEG-YSKEDIDAMSRFRLGMPMGFLELMDF 234
>UniRef50_Q0LZ25 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Caulobacter sp. K31|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Caulobacter sp. K31
Length = 296
Score = 140 bits (338), Expect = 4e-32
Identities = 81/224 (36%), Positives = 126/224 (56%), Gaps = 3/224 (1%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGR-VAKKLYKDDPGKIEGFVKESLDRI 252
IA V A G +V + D + L KA + A L R V++ LY EG +L+ I
Sbjct: 30 IALVFALGGMDVLLHDRDAAALEKALARLSALLDRGVSRGLYT------EGRRATALENI 83
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGI- 429
+++ + + DL+ EA+ E L++K + LD+ PE ++A+NTS++ ++ +G+ +
Sbjct: 84 RLAPDLSRFGDRDLVTEAVFESLEVKGQVLAALDEACPEACVIASNTSTLPISTLGAALS 143
Query: 430 -KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVV 606
+R+ +F G H+F+PV M L+EV+ + S +T K +GK I KD PGF V
Sbjct: 144 PERRPRFLGAHYFSPVSRMLLVEVVPAFETSPETVAWTTSLLKRIGKQPIAVKDVPGFAV 203
Query: 607 NRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
NR+L EA+R+ E G AT ED+D +LG G P+GPF L D
Sbjct: 204 NRMLHAMLIEAVRLVEEGVATPEDLDTACRLGLGHPIGPFALMD 247
>UniRef50_A4ALU9 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like
protein; n=1; marine actinobacterium PHSC20C1|Rep:
3-hydroxyacyl-CoA dehydrogenase-like protein - marine
actinobacterium PHSC20C1
Length = 288
Score = 140 bits (338), Expect = 4e-32
Identities = 78/224 (34%), Positives = 123/224 (54%), Gaps = 2/224 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
I Q+ A G V + D++ L++A+ S+ +L R +K D E R+
Sbjct: 18 IGQLAAMQGIAVRVFDVDEVALDRARASVATSLERFVRKETITDAQS-----HEIQGRMD 72
Query: 256 ISTKVEDS-VNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
+T ++ + V + IEA+ E L +KQ +F LD+ +LATNTS +S+ I S K
Sbjct: 73 WTTDLDAALVGVEAAIEAVPEVLALKQKVFTDLDERTGPEVMLATNTSQLSITTIASSAK 132
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITC-KDTPGFVVN 609
++ G+HFFNP VMRL+E+I+ S++ Q +++ +GK I C +DTPGF+
Sbjct: 133 HPERVVGMHFFNPPVVMRLVEIIRGTMTSDEMLQRAIDFSDQLGKENIVCQRDTPGFITT 192
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLADY 741
R + E +R++E G A+KED+D ++L PMG F L DY
Sbjct: 193 RAIMALRLECIRIFEEGIASKEDLDKAMRLAFNHPMGQFELNDY 236
>UniRef50_A1IEK7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Candidatus
Desulfococcus oleovorans Hxd3
Length = 387
Score = 140 bits (338), Expect = 4e-32
Identities = 82/225 (36%), Positives = 127/225 (56%), Gaps = 3/225 (1%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLG-RVAK-KLYKDDPGKIEGFVKESLDR 249
IAQV AG V +VD++ E L+ K ++ ++ V K KL +D ++ G + SLD
Sbjct: 21 IAQVCIMAGYTVVMVDVKQEFLDNGMKKVKESMDFLVGKGKLSAEDKDRMMGQLSTSLDN 80
Query: 250 IKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGI 429
V D ++IEA+ E +D+K+ +F + AP +LA+NTS++S+ I + +
Sbjct: 81 ---KAAVAD---VQVVIEAVPEIMDLKKKVFADVSSAAPAEALLASNTSTMSITEIATAV 134
Query: 430 KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCI-TCKDTPGFVV 606
+ ++F G+HFFNPV M+L+EVI + S + + E K +GK + KD+PGF+V
Sbjct: 135 TKPERFLGMHFFNPVNRMKLVEVIFGEKTSAENVDLLCELSKKIGKIPVKVLKDSPGFIV 194
Query: 607 NRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLADY 741
NRI P A + + G ++ID +K G PMGPF LADY
Sbjct: 195 NRIGAPNQALISAILDEGAIKPDEIDAIMK-QMGMPMGPFELADY 238
>UniRef50_Q8FRT3 Cluster: Putative 3-hydroxybutyryl-CoA
dehydrogenase; n=2; Corynebacterineae|Rep: Putative
3-hydroxybutyryl-CoA dehydrogenase - Corynebacterium
efficiens
Length = 294
Score = 139 bits (337), Expect = 6e-32
Identities = 81/221 (36%), Positives = 122/221 (55%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IA AG +VT+VD+ + A++ I ++ K+ EG V++ LDR+
Sbjct: 35 IAHSFLAAGAHVTVVDINDAAVEAARERITNDIEGSIKR-------GAEGTVEQWLDRLT 87
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
+ST + +++EA+ E +D+K D F K+ AP ++ATNTSS+SV+ + +
Sbjct: 88 LSTDTAAFADHPVVVEAVPEIIDLKADSFRKIAAAAPG-AVIATNTSSLSVSDLALSVD- 145
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRI 615
+ GLH+FNPVP +L+EV+ +D E EW +GKT I KD PGF +R+
Sbjct: 146 -NPVIGLHYFNPVPASKLVEVVVADSTPEALVDLAREWVAGLGKTPIVVKDAPGFASSRL 204
Query: 616 LXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+ EA+RM E G A+ EDID + LG FP+GP L D
Sbjct: 205 GVAIALEAIRMVEEGVASPEDIDNAMVLGYKFPVGPLKLTD 245
>UniRef50_Q2B4D1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Firmicutes|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Bacillus sp. NRRL B-14911
Length = 295
Score = 139 bits (337), Expect = 6e-32
Identities = 78/224 (34%), Positives = 134/224 (59%), Gaps = 3/224 (1%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGF-VKESLDRI 252
IA + A G T+ D++ + L++AQ+ ++ + + A K GK+ ++ + R+
Sbjct: 22 IAMLCALGGFETTLHDMQEKALDQAQEKLRGIMDKWAAK------GKLPSEQIEAAFSRL 75
Query: 253 KISTKVEDSV-NADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGI 429
+ ++ ++V +AD IIEA+VEKL++K+++F+ L+++AP H I ATN+S+I + + +
Sbjct: 76 RCTSDFGEAVKSADFIIEAVVEKLEVKREVFSMLEEMAPPHAIFATNSSTIVNSLLANAA 135
Query: 430 KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITC-KDTPGFVV 606
R +K +HFF P VM +EV+ S SE+T + ME ++ +T + K+ GFV
Sbjct: 136 DRPEKTVNMHFFFPPLVMDCVEVVMSSRTSEETAETAMEVCNAINRTAVLLKKEISGFVA 195
Query: 607 NRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
NRIL EA+++YE+G A +DIDI + P+GPF L D
Sbjct: 196 NRILGALQREAVQLYEQGIADYKDIDIICRKALNHPIGPFELMD 239
>UniRef50_A6CP14 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Bacillus sp. SG-1|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Bacillus sp. SG-1
Length = 293
Score = 139 bits (336), Expect = 8e-32
Identities = 86/223 (38%), Positives = 121/223 (54%), Gaps = 2/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQA--NLGRVAKKLYKDDPGKIEGFVKESLDR 249
IA V+A G T+VD+E L+ AQ + + G KL K++ +G + S D
Sbjct: 27 IAYVSAVGGFQTTLVDVEQRQLDSAQGELTSIFQKGVDRGKLSKEESTDAQGRLSFSTDM 86
Query: 250 IKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGI 429
K VE +ADL+IEA+ EK +IK+ +F K+D+ A E ATNTS++S I S
Sbjct: 87 AKA---VE---SADLVIEAVPEKTEIKKAVFEKIDEYAQESCYFATNTSTMSPTEIASFT 140
Query: 430 KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVN 609
R K +HFFNPV M L+E+++ S++T Q K +GK + + PGFV +
Sbjct: 141 GRPKKVIAMHFFNPVHKMPLVEIVRGLETSDETTQFAENAAKRMGKETVVINEFPGFVTS 200
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
RI EA M + G T E+ID +KLG +PMGPF L D
Sbjct: 201 RISALVGNEAFYMLQEGLGTPEEIDKAIKLGLNYPMGPFELGD 243
>UniRef50_A0QZQ9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Mycobacterium smegmatis str. MC2 155|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Mycobacterium
smegmatis (strain ATCC 700084 / mc(2)155)
Length = 293
Score = 138 bits (335), Expect = 1e-31
Identities = 75/223 (33%), Positives = 124/223 (55%), Gaps = 2/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESL-DRI 252
I QV A +G++V +++ + + ++ SI A L K GK+ K L RI
Sbjct: 23 ITQVFAASGRDVVVLEADQDRIDAGLASISAFLDTGVAK------GKLSETDKSGLLARI 76
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
+T V D + DL++E++ E ++K+DL ++ + +T + TNTS++SV + + +
Sbjct: 77 TATTDVTDLADVDLVVESVTENAEVKKDLLGRVAAVVGVNTPICTNTSALSVTELAAALP 136
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVG-KTCITCKDTPGFVVN 609
+ GLHFFNP P+ R +EV+++ E+ ++ ++G K I KD PGF++N
Sbjct: 137 NPSRVAGLHFFNPAPLQRTVEVVRALQTGEELVDRLVALVDTLGNKDPIVVKDRPGFLLN 196
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+L PY + + Y+ G AT EDID+ LKLG G+ GP L D
Sbjct: 197 ALLLPYLNDVISEYDDGLATAEDIDLALKLGLGYKSGPLELLD 239
>UniRef50_Q3IIH0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4;
Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Pseudoalteromonas haloplanktis (strain TAC 125)
Length = 281
Score = 138 bits (333), Expect = 2e-31
Identities = 80/199 (40%), Positives = 115/199 (57%), Gaps = 2/199 (1%)
Frame = +1
Query: 148 AQKSIQA-NLGRVAKKLYKDDPGKI-EGFVKESLDRIKISTKVEDSVNADLIIEAIVEKL 321
A KS A N+ R+A+K GKI + +L+++ + ++ VN+DLIIEAIVE
Sbjct: 40 ASKSTCAKNISRLARK------GKISDEQASFALEKLYCNAELVAVVNSDLIIEAIVEDF 93
Query: 322 DIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVI 501
K LF+KL + + I+A+NTSS+S+ A S + GLHFFNP P+M L+E+I
Sbjct: 94 TAKMVLFSKLAEFINDSVIVASNTSSLSITAFASVLPNPQNVVGLHFFNPAPIMELVEII 153
Query: 502 KSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRILXPYSAEALRMYERGDATKEDI 681
+ Q + K++GK + ++ PGFVVNR+L P EA+ + G AT +DI
Sbjct: 154 VGHETAPAKIQLLQGLTKNLGKVPVVVQEAPGFVVNRMLIPMINEAVSILAEGVATADDI 213
Query: 682 DIGLKLGAGFPMGPFXLAD 738
D +K GA PMGP LAD
Sbjct: 214 DKAMKFGAHHPMGPLALAD 232
>UniRef50_A1BCA2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Paracoccus denitrificans PD1222|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Paracoccus denitrificans (strain Pd 1222)
Length = 371
Score = 137 bits (332), Expect = 2e-31
Identities = 87/223 (39%), Positives = 119/223 (53%), Gaps = 2/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLG-RV-AKKLYKDDPGKIEGFVKESLDR 249
IAQ A AG V D PE A ++A L RV A KL + D I L R
Sbjct: 16 IAQTYAAAGFAVLATDAVPEARETALGRLRAGLAPRVRAGKLAQADLDAI-------LAR 68
Query: 250 IKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGI 429
I + + DL IEA+VE++ +KQ LF L+ + +LA+NTSS+S+ A+ G+
Sbjct: 69 ITVVDGPKAMGATDLAIEAVVERMPVKQSLFAALEAVVAPDAVLASNTSSLSMAAMAEGL 128
Query: 430 KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVN 609
R ++ GLHFFNP PVM+L+E++ ++ GKT I C D PGF+VN
Sbjct: 129 ARPERLLGLHFFNPAPVMKLVELVAHPGTGAAALDRARRLTEAAGKTVIPCPDRPGFIVN 188
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
R P+ EAL M E G + E ID ++ AG+P+GPF L D
Sbjct: 189 RCARPFYGEALAMLEEGRSAAE-IDAAMQ-AAGYPLGPFGLID 229
Score = 34.3 bits (75), Expect = 3.2
Identities = 17/42 (40%), Positives = 21/42 (50%)
Frame = +1
Query: 601 VVNRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPF 726
+ RI EA + G T++ ID LKLG FP GPF
Sbjct: 292 IARRIEAALVNEAGWLLAEGGTTQQGIDTALKLGLNFPRGPF 333
>UniRef50_O29815 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 304
Score = 136 bits (330), Expect = 4e-31
Identities = 77/222 (34%), Positives = 119/222 (53%), Gaps = 1/222 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKI-EGFVKESLDRI 252
I Q AQ G V +D+ E L K ++I+A + + + K GKI E + L RI
Sbjct: 17 ITQFFAQQGLEVVAIDVSEERLRKGMEAIKAGRFGLQRLVEK---GKITEEEMNAVLSRI 73
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
ST + DL+IEA+ E +++K + ++D A ++ +NTSSIS+ + S +
Sbjct: 74 STSTSHSALKDCDLVIEAVFEDVNLKLKVLREID--AVTDAVIGSNTSSISITKLSSAVS 131
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
++F G+HFFNP + +L+E++K E + +W +GK I D+PGF +R
Sbjct: 132 NPERFLGIHFFNPAQIQKLVELVKGLLSDEKLVNGIRDWFLKLGKVPIVVNDSPGFATSR 191
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+ EAL M + G AT +DIDIG+ LG G+ MGP D
Sbjct: 192 LGLVLGKEALLMVQEGVATPQDIDIGMMLGYGYSMGPIETGD 233
>UniRef50_Q06BB6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Vibrio cholerae|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Vibrio cholerae
Length = 284
Score = 136 bits (329), Expect = 5e-31
Identities = 63/168 (37%), Positives = 104/168 (61%)
Frame = +1
Query: 235 ESLDRIKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNA 414
ES+ ++I++ +A+L+IEA+ E D+K D+ K+ + + TI+A+NTSS+S+
Sbjct: 68 ESMAALQITSDFSALKSAELVIEAVSEDKDVKHDIMAKIAAVVDDTTIVASNTSSLSITE 127
Query: 415 IGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTP 594
+ + ++ + F GLHFFNP P+M L+EV++ E + + + +S+GK + + P
Sbjct: 128 LAANFRKPENFLGLHFFNPAPMMSLVEVVRGLTTCESIIEKAVVFSRSIGKEPVVVNEAP 187
Query: 595 GFVVNRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
GFVVNR+L P EA+ +Y G A + ID +KLGA P+GP L+D
Sbjct: 188 GFVVNRMLIPMINEAIAIYSEGVADIKQIDKAMKLGANHPIGPLSLSD 235
>UniRef50_Q6MM12 Cluster: Fatty oxidation complex, alpha subunit;
n=1; Bdellovibrio bacteriovorus|Rep: Fatty oxidation
complex, alpha subunit - Bdellovibrio bacteriovorus
Length = 717
Score = 135 bits (327), Expect = 9e-31
Identities = 81/221 (36%), Positives = 117/221 (52%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IA V A G V + DL + L K K ++ K+ D K + ++ +D +
Sbjct: 333 IAYVAADKGIQVRMKDLNTDALGKGLKHASDLWMKLVKRKSID---KYQ--FQQKMDLVS 387
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
+ST N D+++EAIVE + IKQ + + I+ATNTSS+SV + G R
Sbjct: 388 VSTDYAGFKNLDVVVEAIVEDMGIKQKVIGECAGQMRPDAIIATNTSSLSVTEMAKGHPR 447
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRI 615
+ F G+HFFNPV M L+EVI+ + S++T + E K +GK + KD PGF+VNR+
Sbjct: 448 PEYFAGMHFFNPVNKMPLIEVIRGEKTSDETIATIYELSKKMGKMPVVVKDGPGFLVNRL 507
Query: 616 LXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
L PY EA + + G + E +D G PMGPF L D
Sbjct: 508 LLPYMGEAAFLLQEG-MSIEFVDKVYVKEFGMPMGPFELMD 547
>UniRef50_Q6V1N6 Cluster: PlmT8; n=1; Streptomyces sp. HK803|Rep:
PlmT8 - Streptomyces sp. HK803
Length = 571
Score = 135 bits (326), Expect = 1e-30
Identities = 76/221 (34%), Positives = 122/221 (55%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IAQ A+AG T+V +A +++ +L R ++ + P ++ + ESL +
Sbjct: 305 IAQACARAGYPTTLVARSEVRAKEALATVENSLNRAVQR-GRLTPEQLTSSM-ESLTGV- 361
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
+++E DL++EA+VE +D+K+ +F +LD + T+LAT+TSS+ V R
Sbjct: 362 --SRLEAVAACDLVVEAVVEDIDVKRTVFRELDAVCGAQTVLATSTSSLPVIECAMATGR 419
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRI 615
+ G+HFFNP PVM+L+EV+++ S +T ++GK + C D GF+VN +
Sbjct: 420 PEAVVGMHFFNPAPVMKLVEVVRTALTSRETLGVAHATATALGKRPVGCLDRSGFIVNAL 479
Query: 616 LXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
L PY A+ + + G T E ID + LG G PMGP L D
Sbjct: 480 LFPYLNRAVALLDEGILTAEGIDTVMALGQGHPMGPLQLLD 520
Score = 83.0 bits (196), Expect = 7e-15
Identities = 48/165 (29%), Positives = 80/165 (48%), Gaps = 2/165 (1%)
Frame = +1
Query: 250 IKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGI 429
I ++T+ D V+ADL+IEA+ E++ K +L + + AT TS ++V I G
Sbjct: 56 IDLTTRSADIVSADLVIEAVPERMKTKCELLSHAHNACAPGAVFATTTSGLAVTDIAFGS 115
Query: 430 KRKDKFGGLHFF--NPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFV 603
R + GLH F P+ +EV+ + + + +G+ ++ D GFV
Sbjct: 116 GRPCRTVGLHLFPQGPMDPATAVEVVGTPLTDGSVLADVQALIRDLGQVPVSVPDRAGFV 175
Query: 604 VNRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+ Y +A MYE+ A+++ ID ++LG G P GP D
Sbjct: 176 GGALTMAYLNDAATMYEQRYASRDGIDTAMRLGCGLPRGPLAHLD 220
>UniRef50_A0ISW5 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Serratia proteamaculans 568|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding - Serratia
proteamaculans 568
Length = 509
Score = 135 bits (326), Expect = 1e-30
Identities = 80/223 (35%), Positives = 116/223 (52%), Gaps = 1/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVK-ESLDRI 252
IA + AQ G + + LN+A+ I +L + K D GKI K E L +
Sbjct: 23 IAYLLAQNGIRTLLYNRSGNNLNQARDYIIRDLDK------KIDGGKISPQKKGEILANL 76
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
S E ++DL+IE I E K ++ + + I+ATNTSS+S+N + +G++
Sbjct: 77 VFSPIFEAIADSDLVIETIAEHEATKHEILAAIAATVKKEAIIATNTSSLSLNKLAAGVE 136
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
+F GLHFFNP P+M+L+E+I S S T + ++GK + CK TPGF+VNR
Sbjct: 137 NNARFIGLHFFNPAPLMKLIEIIPSYFTSRATSLRCQQLVTAIGKQFVVCKATPGFIVNR 196
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLADY 741
+ P+ E R+ E A ID LK G F MGP L D+
Sbjct: 197 MARPFYLEGFRLLEENVALAPQIDRALKAGGHFRMGPLELTDF 239
Score = 37.5 bits (83), Expect = 0.34
Identities = 18/48 (37%), Positives = 26/48 (54%)
Frame = +1
Query: 583 KDTPGFVVNRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPF 726
KD+PG +V R+L E++ M E G ++ DIDI G + G F
Sbjct: 417 KDSPGLIVARVLSSLINESVIMVESGVCSRADIDIAAVAGVNYADGIF 464
>UniRef50_Q5NW50 Cluster: DitN-like 3-hydroxyacyl-CoA
dehydrogenase,possibly related to diterpenoid
metabolism; n=6; Proteobacteria|Rep: DitN-like
3-hydroxyacyl-CoA dehydrogenase,possibly related to
diterpenoid metabolism - Azoarcus sp. (strain EbN1)
(Aromatoleum aromaticum (strain EbN1))
Length = 299
Score = 134 bits (324), Expect = 2e-30
Identities = 75/222 (33%), Positives = 123/222 (55%), Gaps = 1/222 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IA A +G + +VD P L+KA I + L KL K +E K +L+R++
Sbjct: 19 IAYSCAISGYRILLVDANPSALDKAVGQINS-LVAAGVKLGK----LVEAAGKAALERLE 73
Query: 256 ISTKVEDSVN-ADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
+ +++ + A L+IE EK+DIK + K D+L P I+A+NTS++S++ + + +
Sbjct: 74 AAIELDGRASDAALLIETATEKIDIKLAIIGKADELLPPEAIIASNTSALSISELAAATR 133
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
R +F G+HFFNPV M+L+E+I+ ++ T + + ++GKT I + PGF +R
Sbjct: 134 RPTQFAGMHFFNPVHKMKLVELIRGIETTQATVERLKAVTAALGKTSIVVNEAPGFTTSR 193
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+ EA+ M G A+ +DID L++ PMGP L D
Sbjct: 194 MSALMGNEAMYMLAEGVASADDIDTSLRMAFNHPMGPLELGD 235
>UniRef50_A0K022 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=9; Actinomycetales|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Arthrobacter sp. (strain FB24)
Length = 290
Score = 134 bits (324), Expect = 2e-30
Identities = 70/213 (32%), Positives = 115/213 (53%)
Frame = +1
Query: 100 GQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIKISTKVEDS 279
G NV +V+ + A++ +++ AK + + G +G + E + R+ ++ +D
Sbjct: 34 GANVLVVERDEASAEAARERVES---AAAKSIER---GATDGNLDEMVSRLSVTVDYDDF 87
Query: 280 VNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKRKDKFGGLH 459
+ +L++EA+ E ++K +++ + LA+NTSS+SVN + +KR F GLH
Sbjct: 88 KDRELVVEAVPEDWELKVASLREIEARLSDDAYLASNTSSLSVNGLARELKRPGNFLGLH 147
Query: 460 FFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRILXPYSAEA 639
FFNPVP L+EV+ + S D A W +++GKT + D PGF +R+ + EA
Sbjct: 148 FFNPVPASTLIEVVLGEQTSPDLAAAAKRWVEALGKTAVVVNDAPGFASSRLGVAIALEA 207
Query: 640 LRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+RM E G A+ EDID + LG P GP D
Sbjct: 208 MRMVEEGVASAEDIDNAMVLGYKHPTGPLRTTD 240
>UniRef50_Q7WCB1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4;
Bordetella|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Bordetella parapertussis
Length = 354
Score = 134 bits (323), Expect = 3e-30
Identities = 77/212 (36%), Positives = 120/212 (56%), Gaps = 1/212 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IA + A G +V ++D L +A + I+ LG +Y D + ++ RI+
Sbjct: 64 IAALFASKGFDVVLIDPMAGALTRAAQVIERQLG-----VYAPDA------IAPAMQRIR 112
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
+ +E + +A L+IEA+ EKL +K+D+F +LD L I ATNTS +S+N I + R
Sbjct: 113 MDAGLEAACSAQLVIEAVPEKLALKRDIFARLDTLCDPQAIFATNTSGLSINDIAQAVTR 172
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGK-TCITCKDTPGFVVNR 612
+D+F G HFF P V+ L+EV+++D SE T +M ++ GK + KD PGF+ NR
Sbjct: 173 RDRFVGTHFFTPADVIPLVEVVRNDDTSEQTVARVMGMLRAGGKRPVLVRKDIPGFIANR 232
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAG 708
I + EA+ + E+G A+ EDID +K G
Sbjct: 233 IQHALAREAISLLEKGVASAEDIDEVVKWSLG 264
>UniRef50_Q9ADL9 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase;
n=7; Bacteria|Rep: Beta-hydroxybutyryl-CoA dehydrogenase
- Polyangium cellulosum (Sorangium cellulosum)
Length = 293
Score = 132 bits (320), Expect = 7e-30
Identities = 77/221 (34%), Positives = 118/221 (53%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
+AQ AQ G +V +VD+ L +A+ I+ L V +D K G K L+R+
Sbjct: 24 VAQSLAQTGHDVVLVDVSEAALARARMGIRNGLRAVTLFGSAEDK-KRAGDPKAVLERVA 82
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
+T AD ++E + EK DIK++++ +L+ + I A +TS+IS+ IGS KR
Sbjct: 83 FTTDYGRLAGADFVVENVTEKWDIKREVYARLEGVCRPEIIFAADTSAISITRIGSVTKR 142
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRI 615
+ G+HF NPVP+ ++EVI+ H S +T A + +GKTC+ +D PGFV NR+
Sbjct: 143 PSQVVGMHFMNPVPLKPMVEVIRGFHTSPETLGAAKRFLAEMGKTCVVVEDAPGFVSNRV 202
Query: 616 LXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
L EA+ + + A+ D+D K MGP AD
Sbjct: 203 LMLTINEAIFLVQDQVASAADVDRIFKGCFEHKMGPLETAD 243
>UniRef50_Q0SEV8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=34;
Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Rhodococcus sp. (strain RHA1)
Length = 298
Score = 132 bits (318), Expect = 1e-29
Identities = 78/224 (34%), Positives = 122/224 (54%), Gaps = 3/224 (1%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLD-RI 252
IA+V A+A +V + + E+ + I +L R GKI +E R+
Sbjct: 21 IAEVCARAHVDVLVFEQTRELAAAGRSRILRSLDRGVSS------GKITEREREQAAWRL 74
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPE-HTILATNTSSISVNAIGSGI 429
+ ++ + D + L++EA+VE +K ++F +LD++ + + +LA+NTSSI + +G
Sbjct: 75 RFTSDLGDFADRQLVVEAVVEDEKVKSEIFTELDQVVTDPNAVLASNTSSIPIMKLGIAT 134
Query: 430 KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSV-GKTCITCKDTPGFVV 606
K ++ G+HFFNPVPV+ L+E++ + S+ + + V GK + D GFVV
Sbjct: 135 KSPERVIGMHFFNPVPVLPLVELVTTLKTSKSVSERAEAFASDVLGKQVVRSADRSGFVV 194
Query: 607 NRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
N +L PY A+RM E G ATKEDID LG PMGP L D
Sbjct: 195 NALLVPYLLSAIRMVESGFATKEDIDKATVLGLAHPMGPLALTD 238
>UniRef50_Q8W1L6 Cluster: Peroxisomal fatty acid beta-oxidation
multifunctional protein (MFP) [Includes: Enoyl-CoA
hydratase/3-2-trans-enoyl-CoA isomerase/3-
hydroxybutyryl-CoA epimerase (EC 4.2.1.17) (EC 5.3.3.8)
(EC 5.1.2.3); 3-hydroxyacyl-CoA dehydrogenase (EC
1.1.1.35)]; n=23; Magnoliophyta|Rep: Peroxisomal fatty
acid beta-oxidation multifunctional protein (MFP)
[Includes: Enoyl-CoA hydratase/3-2-trans-enoyl-CoA
isomerase/3- hydroxybutyryl-CoA epimerase (EC 4.2.1.17)
(EC 5.3.3.8) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)] - Oryza sativa subsp.
japonica (Rice)
Length = 726
Score = 132 bits (318), Expect = 1e-29
Identities = 76/224 (33%), Positives = 119/224 (53%), Gaps = 3/224 (1%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKK--LYKDDPGKIEGFVKESLDR 249
IA + +V + ++ P+ L + QK I ANL + K+ L KD K +K +LD
Sbjct: 324 IATALLVSNTSVVLKEVNPQFLQRGQKMIAANLEGLVKRGSLTKDKMNKAMSLLKGALD- 382
Query: 250 IKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGI 429
D + D++IEA++EK+ +KQ +F+ L+K+ P H ILATNTS+I +N +G
Sbjct: 383 ------YSDFKDVDMVIEAVIEKIPLKQSIFSDLEKVCPPHCILATNTSTIDLNVVGEKT 436
Query: 430 KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVN 609
+D+ G HFF+P +M LLE+++++ S ++ GK + K + + GF VN
Sbjct: 437 NSQDRIIGAHFFSPAHIMPLLEIVRTEKTSPQAILDLITVGKMIKKVPVVVGNCTGFAVN 496
Query: 610 RILXPYSAEALRMYERG-DATKEDIDIGLKLGAGFPMGPFXLAD 738
R PY+ + + G D + D I G PMGPF L D
Sbjct: 497 RTFFPYTQGSHLLVSIGIDVFRIDRVIS---SFGMPMGPFQLQD 537
>UniRef50_Q39TJ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like; n=1;
Geobacter metallireducens GS-15|Rep: 3-hydroxyacyl-CoA
dehydrogenase-like - Geobacter metallireducens (strain
GS-15 / ATCC 53774 / DSM 7210)
Length = 290
Score = 131 bits (316), Expect = 2e-29
Identities = 79/224 (35%), Positives = 120/224 (53%), Gaps = 3/224 (1%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IA A AG +V + ++ L+ A ++ G +AK K K ++ RI
Sbjct: 19 IALSCALAGYDVLLKEVS---LDLAAAGVERIRGSLAKWSEKGRLAVDAEQQKSAVARIT 75
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIG---SG 426
+ DL+IEAI E LD+K F +L+++ I+A+NTSS+ + +G S
Sbjct: 76 PVDNFSGFGDVDLVIEAIFEDLDVKSQNFRQLEEVCKPSCIIASNTSSLPITKLGACFSS 135
Query: 427 IKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVV 606
+RK +F G+HFF+P +M+L+EV+ + S +T + + S+GK I D GFVV
Sbjct: 136 AERKSRFVGMHFFSPAAIMKLVEVVNGEDTSAETVETACAFCTSIGKEPIKVNDCAGFVV 195
Query: 607 NRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
NRIL + EA+R+ E A+ DID +LG G P+GPF L D
Sbjct: 196 NRILGAINDEAIRLLEENVASAADIDKACQLGLGHPVGPFALMD 239
>UniRef50_A0W3T3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Geobacter lovleyi SZ|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor - Geobacter
lovleyi SZ
Length = 285
Score = 131 bits (316), Expect = 2e-29
Identities = 77/222 (34%), Positives = 119/222 (53%), Gaps = 1/222 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKK-LYKDDPGKIEGFVKESLDRI 252
IAQ+ A AG V + L A I+ +L ++ +K L ++P I + + +
Sbjct: 20 IAQLAAMAGFRVRLYARHASALADAAGRIETSLAKLHEKGLIGEEPTVIRARISNCHEPV 79
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
+S + DL+IEAI E++ K +L +L + + ILA++TSS+S+ A+G+
Sbjct: 80 ALS-------DCDLVIEAIAEQMAAKCELLAELGAVLGKEAILASSTSSLSITALGAASG 132
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
+F G+HF NPVP+M L+E+I S T + ++GK + KD PGF++ R
Sbjct: 133 IPQRFIGMHFMNPVPLMELVELIAGSETSPRTIDIARQMVTALGKQSVCSKDQPGFIITR 192
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+L EA M + G A EDID ++LGA PMGP LAD
Sbjct: 193 LLCVLINEAFGMLQDGIAAAEDIDTAMQLGAHHPMGPLALAD 234
>UniRef50_A3M4C7 Cluster: PaaC; n=1; Acinetobacter baumannii ATCC
17978|Rep: PaaC - Acinetobacter baumannii (strain ATCC
17978 / NCDC KC 755)
Length = 435
Score = 130 bits (315), Expect = 3e-29
Identities = 67/158 (42%), Positives = 93/158 (58%)
Frame = +1
Query: 265 KVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKRKDK 444
+VE +ADL+IEA+VEK ++KQ LF +L ++ TI A+NTSSISV AI +GI ++
Sbjct: 4 QVEALRDADLVIEAVVEKKEVKQSLFKQLAEICSAQTIFASNTSSISVTAISAGIAHPER 63
Query: 445 FGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRILXP 624
GLHFFNP PVM+L+E+++ A+ K + K TPGF+VNRI P
Sbjct: 64 VVGLHFFNPAPVMKLVEIVQGLKTPNSLCLALKNLMLDWKKIPVLTKSTPGFIVNRIARP 123
Query: 625 YSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+ AE R + + + +D LK GF MGP L D
Sbjct: 124 FYAEGFRALQEQVTSYDQLDYALKQCGGFAMGPCELTD 161
Score = 35.9 bits (79), Expect = 1.0
Identities = 22/78 (28%), Positives = 35/78 (44%), Gaps = 1/78 (1%)
Frame = +1
Query: 496 VIKSDHISEDTYQAMME-WGKSVGKTCITCKDTPGFVVNRILXPYSAEALRMYERGDATK 672
V+ + + E A +E + G + + KD P + R + EA G A+
Sbjct: 303 VLSHNELCETNDLAKVEAYFAQFGMSVMWIKDHPALLTLRTIALLINEACEASLHGVASL 362
Query: 673 EDIDIGLKLGAGFPMGPF 726
EDID +K G +P GP+
Sbjct: 363 EDIDNAMKYGVNYPKGPY 380
>UniRef50_A4FGV2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Actinomycetales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Saccharopolyspora erythraea (strain NRRL 23338)
Length = 517
Score = 130 bits (313), Expect = 5e-29
Identities = 75/223 (33%), Positives = 120/223 (53%), Gaps = 2/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLD-RI 252
IAQ+ A AG V + D E ++ A + G++ K G++ ++ R+
Sbjct: 23 IAQLAAAAGLTVELADARQEAVSAAVDHVGEMFGKLVGK------GRMSAEEADAATARL 76
Query: 253 K-ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGI 429
+ + + + + DL++EA+ E LD K++LF L+++ P H +LATNTSS+SV AIG+ +
Sbjct: 77 RPVGDPLAPADSCDLVVEAVREDLDTKRELFAGLEEVCPRHAVLATNTSSLSVTAIGAAL 136
Query: 430 KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVN 609
+ GLHFFNPVP+M+L+EVI +D ++E + +G + DTPGF+VN
Sbjct: 137 ADPSRLIGLHFFNPVPLMKLVEVIPGARTRQDLSADLVELVRRLGHQPVLATDTPGFLVN 196
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+ EAL++ D+D + G MGPF L D
Sbjct: 197 HAGRGLATEALQIMSESAVEPSDVDRIARDVLGLRMGPFELLD 239
>UniRef50_A5V327 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Sphingomonas wittichii RW1
Length = 748
Score = 126 bits (304), Expect = 6e-28
Identities = 74/223 (33%), Positives = 123/223 (55%), Gaps = 2/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKK--LYKDDPGKIEGFVKESLDR 249
IA A AG V IVD E L++ + ++AN K+ + ++ K + + DR
Sbjct: 359 IAMCFAGAGIPVVIVDTTQEALDRGMERVRANYATSVKRGSISQEQVDKRLALITPATDR 418
Query: 250 IKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGI 429
++ +ADL+IEA+ E + +K+++F+ L+K T+LA+NTS++ V+ I + +
Sbjct: 419 AAVA-------DADLVIEAVFEDMAVKKEIFSDLEKRVKPGTVLASNTSALDVDEIAAAL 471
Query: 430 KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVN 609
R + F G+HFF+P VM+LLEV+++ S + M G+ +GK + + GF+ N
Sbjct: 472 DRPEDFVGMHFFSPANVMKLLEVVQAAKSSPEAILTAMAVGRKIGKVPVWSGNCDGFIGN 531
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
R++ SA+A R+ +RG A +D L GFPMGP D
Sbjct: 532 RMVAKRSAQAERLLQRG-AFPPQVDAAL-TKLGFPMGPLTTND 572
>UniRef50_Q7VRZ0 Cluster: Probable enoyl-CoA
hydratase/3-hydroxyacyl-CoA dehydrogenase, bifunctional
enzyme; n=3; Bordetella|Rep: Probable enoyl-CoA
hydratase/3-hydroxyacyl-CoA dehydrogenase, bifunctional
enzyme - Bordetella pertussis
Length = 705
Score = 125 bits (302), Expect = 1e-27
Identities = 74/222 (33%), Positives = 123/222 (55%), Gaps = 1/222 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKI-EGFVKESLDRI 252
IA A AG V +D+E L++A ++I+A+ +A + G++ E ++++ RI
Sbjct: 318 IAIALADAGLRVRFIDVEQASLDRALEAIRAHYRSLAAR------GRMTEAAARDAVARI 371
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
++ ++ + AD+++EA E L IKQ +F +LD + +LATNTS++ V+AI + +
Sbjct: 372 SPASDMQAAAEADVVVEAAFEDLAIKQAIFRQLDSIVRPGAVLATNTSTLDVDAIAAATR 431
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
R G HFF+P VMRLLEV++ + T A++ G+ +GK C+T GFV NR
Sbjct: 432 RPQDVVGTHFFSPANVMRLLEVVRGARTAPRTLGAVLALGRRMGKVCVTVGVCDGFVANR 491
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+ + A + + + A +DID + GF MGP D
Sbjct: 492 -MSAHRARQIELLLQHGALPQDIDQAAR-EFGFSMGPCAATD 531
>UniRef50_Q2S2J8 Cluster: Fatty oxidation complex, alpha subunit;
n=2; Bacteria|Rep: Fatty oxidation complex, alpha
subunit - Salinibacter ruber (strain DSM 13855)
Length = 719
Score = 125 bits (302), Expect = 1e-27
Identities = 73/222 (32%), Positives = 123/222 (55%), Gaps = 1/222 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESL-DRI 252
IAQV+AQ G +V + D + + +K+I + + ++D G I F ++ + +R+
Sbjct: 333 IAQVSAQNGLDVVLTDQSLALAAEGKKAIWSAVTE------QEDKGIINTFTRDQIVERV 386
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
+ AD++IEA+ E L IK + ++++ + T+LA+NTS++ ++ I G+
Sbjct: 387 APTADYAPLQAADVVIEAVPEDLSIKHAVLSEVETVVDADTVLASNTSALPISTIAEGVD 446
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
+ G+H+F+PVP + LLE++ ++ S++ G + KT I D PGF R
Sbjct: 447 DPSRVLGMHYFSPVPDIPLLEIVVTEETSDEALATAYAAGLAQDKTVIVVNDGPGFYTTR 506
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
IL Y EAL ++E G A E +D + + AGFPMGPF L D
Sbjct: 507 ILALYMNEALLLFEAG-AEIEAVDEAM-MDAGFPMGPFELFD 546
>UniRef50_Q668V1 Cluster: Fatty acid oxidation complex subunit alpha
[Includes: Enoyl-CoA hydratase/3-hydroxybutyryl-CoA
epimerase (EC 4.2.1.17) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)]; n=95; Proteobacteria|Rep:
Fatty acid oxidation complex subunit alpha [Includes:
Enoyl-CoA hydratase/3-hydroxybutyryl-CoA epimerase (EC
4.2.1.17) (EC 5.1.2.3); 3-hydroxyacyl-CoA dehydrogenase
(EC 1.1.1.35)] - Yersinia pseudotuberculosis
Length = 753
Score = 124 bits (298), Expect = 3e-27
Identities = 81/223 (36%), Positives = 118/223 (52%), Gaps = 2/223 (0%)
Frame = +1
Query: 76 IAQVTA-QAGQNVTIVDLEPEILNKAQKSIQANLG-RVAKKLYKDDPGKIEGFVKESLDR 249
IA VTA +AG V I D+ P+ +N+A K LG RV K + + + +
Sbjct: 330 IANVTATRAGLPVRIKDINPQGINQALKYTWDALGKRVRSKRMRPTEQQRQMML------ 383
Query: 250 IKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGI 429
I ST D+++EA+ E L +KQ + +++ HTI A+NTSS+ ++ I +
Sbjct: 384 ISGSTDYRGFERVDIVVEAVFEDLSLKQQMVADIERFGAAHTIFASNTSSLPISQIAALA 443
Query: 430 KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVN 609
+R ++ GLH+F+PV M L+EVI + SE+T + + GKT I D GF VN
Sbjct: 444 QRPEQVIGLHYFSPVDKMPLVEVIPHEKTSEETIATTVALARKQGKTAIVVADRAGFYVN 503
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
RIL PY EA R G+ E +D L + GFP+GP L D
Sbjct: 504 RILAPYINEAARCLLDGEPI-ESVDNAL-VDFGFPVGPMMLLD 544
>UniRef50_Q5P5K3 Cluster: Alpha-subunit of fatty acid oxidation
complex; n=5; Betaproteobacteria|Rep: Alpha-subunit of
fatty acid oxidation complex - Azoarcus sp. (strain
EbN1) (Aromatoleum aromaticum (strain EbN1))
Length = 678
Score = 123 bits (297), Expect = 4e-27
Identities = 84/225 (37%), Positives = 117/225 (52%), Gaps = 4/225 (1%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAK----KLYKDDPGKIEGFVKESL 243
IA V A AG VT+ D +A + I +GR AK KL D K V+ +L
Sbjct: 331 IAAVCALAGMTVTLQD-------QAVERIAPAVGRAAKLFERKLRGDTATKARQ-VRFAL 382
Query: 244 DRIKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGS 423
DR+ + AD++IEAI E LD K+ LF +L++ A +LATNTSS+ + IG+
Sbjct: 383 DRLIPDPHGHGARRADVVIEAIFENLDAKRALFAQLERRARPDAVLATNTSSLRIEDIGA 442
Query: 424 GIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFV 603
+ + G+HFFNPV M L+EV+ + D + + + K + + PGF+
Sbjct: 443 ELANPARLVGIHFFNPVAQMPLVEVVAGEASDADALYRAAAFVRRLDKLPLPVRSAPGFL 502
Query: 604 VNRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
VN +L PY EALR E G A E +D L + G PMGP L D
Sbjct: 503 VNAVLGPYMLEALRCVEEGVA-PEAVDAAL-VAFGMPMGPVELVD 545
>UniRef50_A5D5N2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Pelotomaculum thermopropionicum SI|Rep:
3-hydroxyacyl-CoA dehydrogenase - Pelotomaculum
thermopropionicum SI
Length = 319
Score = 123 bits (296), Expect = 5e-27
Identities = 72/205 (35%), Positives = 118/205 (57%), Gaps = 2/205 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDR-I 252
IA Q G +V ++D+ L A++ IQ+ L A K G + G + L+ +
Sbjct: 19 IAAAALQHGVSVRLIDVSAPALETARRKIQSYLASAAGK-GGGKGGAVPGHLAGVLETCM 77
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
+++ V AD++IEA+ EKLD+K+++F +LDKL P ILATNTS + + AI S
Sbjct: 78 EMAAGV---TGADMVIEAVPEKLDLKKEIFAQLDKLCPPSVILATNTSGLPITAIASAAA 134
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVG-KTCITCKDTPGFVVN 609
R ++ G HF+ P ++ L+EV+ SD+ S D + + +S+G K + KD PGF+ N
Sbjct: 135 RPERVLGTHFYMPAYLIPLVEVVCSDYTSPDVAGDTVAFLQSIGRKPVLVKKDIPGFIGN 194
Query: 610 RILXPYSAEALRMYERGDATKEDID 684
R+ + EA+ + ++G A+ +DID
Sbjct: 195 RLQHAIAREAISLLQKGIASAQDID 219
>UniRef50_Q64428 Cluster: Trifunctional enzyme subunit alpha,
mitochondrial precursor (TP-alpha) [Includes: Long-chain
enoyl-CoA hydratase (EC 4.2.1.17); Long chain 3-
hydroxyacyl-CoA dehydrogenase (EC 1.1.1.211)]; n=43;
Bilateria|Rep: Trifunctional enzyme subunit alpha,
mitochondrial precursor (TP-alpha) [Includes: Long-chain
enoyl-CoA hydratase (EC 4.2.1.17); Long chain 3-
hydroxyacyl-CoA dehydrogenase (EC 1.1.1.211)] - Rattus
norvegicus (Rat)
Length = 763
Score = 123 bits (296), Expect = 5e-27
Identities = 71/220 (32%), Positives = 118/220 (53%), Gaps = 7/220 (3%)
Frame = +1
Query: 100 GQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIKISTKVEDS 279
G + V ++ + + + LGR ++++K K++ S +R I + +
Sbjct: 373 GAGIAQVSVDKGLKTLLKDTTVTGLGRGQQQVFKGLNDKVKKKALTSFERDSIFSNLIGQ 432
Query: 280 VN------ADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKRKD 441
++ AD++IEA+ E L +K + +++ + PEH I A+NTS++ +N I + +R +
Sbjct: 433 LDYKGFEKADMVIEAVFEDLAVKHKVLKEVESVTPEHCIFASNTSALPINQIAAVSQRPE 492
Query: 442 KFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRILX 621
K G+H+F+PV M+LLE+I +D S+DT + + G GK I KD PGF R L
Sbjct: 493 KVIGMHYFSPVDKMQLLEIITTDKTSKDTTASAVAVGLKQGKVIIVVKDGPGFYTTRCLA 552
Query: 622 PYSAEALRMYERG-DATKEDIDIGLKLGAGFPMGPFXLAD 738
P +E +R+ + G D K D L G GFP+G LAD
Sbjct: 553 PMMSEVIRILQEGVDPKKLD---ALTTGFGFPVGAATLAD 589
>UniRef50_Q93HI5 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2;
Actinomycetales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Streptomyces avermitilis
Length = 272
Score = 122 bits (295), Expect = 7e-27
Identities = 77/223 (34%), Positives = 116/223 (52%), Gaps = 2/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
+A+V A+AG +V + + L + + ++ +L +K D + +E+L R+
Sbjct: 6 LAEVCARAGLDVLVTSSGEDGLARGRGRLERSLAHAVRKDRISDTAR-----EETLARVS 60
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPE-HTILATNTSSISVNAIGSGIK 432
+T + + L++EA E K +F LD+ + ILATNTS++ V +
Sbjct: 61 FTTDLAAFRDRQLVLEAAPEDEPTKLRIFQALDRAVEDPEAILATNTSALPVMRLARATD 120
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSV-GKTCITCKDTPGFVVN 609
R + GLHFFNP PV+ L+EVI S + T + E+ +V GK + D GFVVN
Sbjct: 121 RPGQVLGLHFFNPAPVLPLVEVIGSLLTRDRTRRIAAEFATTVLGKQVVHAGDRSGFVVN 180
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+L PY A+RM E G A +DID + LG PMGP LAD
Sbjct: 181 ALLIPYLLSAIRMCEAGFAGAQDIDKAMTLGCSHPMGPLALAD 223
>UniRef50_Q67L77 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Symbiobacterium thermophilum|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Symbiobacterium thermophilum
Length = 296
Score = 122 bits (295), Expect = 7e-27
Identities = 66/221 (29%), Positives = 117/221 (52%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IAQ+ A G V +V E L +A++ + L +K K + L RI
Sbjct: 18 IAQLVATQGLEVIMVGRSEEELEQARRQLDLALQHEIEKWALTQSEK-----RAILARIS 72
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
++T + + AD +I +V ++ +++F LD++ ILA+NTS++S+ + S R
Sbjct: 73 MTTDINELAKADFVIATLVVEIAEDKEIFRTLDQVCRREVILASNTSTLSITEMASATNR 132
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRI 615
DK G HF P+P R+++V++ S++T +M + +G+T + ++PG++ R+
Sbjct: 133 PDKVIGCHFLQPIPRTRVVQVVRGLKTSDETVSQVMALMERLGRTGVEVFESPGYITTRL 192
Query: 616 LXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+ P EA ++ G A+ EDID ++LG P GP +AD
Sbjct: 193 IVPLINEACQVLMEGVASAEDIDTAMRLGFEMPRGPLEIAD 233
>UniRef50_A0LDJ8 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Magnetococcus sp. MC-1|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Magnetococcus sp. (strain MC-1)
Length = 717
Score = 122 bits (295), Expect = 7e-27
Identities = 78/221 (35%), Positives = 115/221 (52%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IA A G V++ L E+L +A + ++A+K D ++ LDR+
Sbjct: 324 IAVWCALQGMQVSLQGLSTELLGRALQEAT----QLARKKRLDRLA-----TRDLLDRLM 374
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
+ + +ADL+IEAI E + KQ L+ L+ EH +LATNTS+I + + G+KR
Sbjct: 375 PDQRGDGVCHADLVIEAIFEDVTAKQQLYAALEPRMREHALLATNTSAIPLQTLAQGLKR 434
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRI 615
+ GLHFFNPV M L+EV++ S Q + ++ + + K PGF+VNR+
Sbjct: 435 PQQLLGLHFFNPVARMPLVEVVEGPQTSMQALQMGYRFVHAIQRLPLPVKSRPGFLVNRV 494
Query: 616 LXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
L PY EA+RM + G ID + G PMGP LAD
Sbjct: 495 LMPYLMEAVRMVDEG-VDMRRID-KAAMDFGMPMGPLALAD 533
>UniRef50_A0HAN1 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Comamonas testosteroni KF-1
Length = 706
Score = 122 bits (295), Expect = 7e-27
Identities = 75/221 (33%), Positives = 118/221 (53%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IA A AG V + + E L++ I+ N ++ G VKE + I+
Sbjct: 320 IAMAFANAGIPVVLCEREQAALDRGMAMIERNY-----QISVSRGGLTAEAVKERMQHIQ 374
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
+ + DL+IEA+ E + IK+D+F +LD++ + TILATNTS +++N I + +R
Sbjct: 375 QTLDLSAFAEVDLVIEAVFEDMAIKRDVFVQLDRICRKGTILATNTSRLNINEIAAVTQR 434
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRI 615
+ GLHFF+P VM+LLEV++ + + + M+ ++GK + GFV NR+
Sbjct: 435 PEDVIGLHFFSPANVMKLLEVVRGERTCDAVIASCMQMAVAIGKIPVLVGVCEGFVGNRM 494
Query: 616 LXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
L Y EA + E G AT + ID ++ GF MGP +AD
Sbjct: 495 LTGYWREAGFLLEEG-ATVQQIDAAMQ-AFGFAMGPLAMAD 533
>UniRef50_Q9HJM0 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase
related protein; n=3; Thermoplasmatales|Rep:
Beta-hydroxybutyryl-CoA dehydrogenase related protein -
Thermoplasma acidophilum
Length = 314
Score = 122 bits (295), Expect = 7e-27
Identities = 69/175 (39%), Positives = 104/175 (59%), Gaps = 5/175 (2%)
Frame = +1
Query: 229 VKESLDRIKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISV 408
V L RI ++ K D + DL+IEA E D+K +F+ + L+ EH I+A+NTSS+S+
Sbjct: 93 VNAMLKRISLTDKYSDLSSCDLVIEAAFENQDVKNRIFSDISDLS-EHAIIASNTSSLSI 151
Query: 409 NAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISED---TYQAMMEWGKS--VGKTC 573
+ S +KR + LHFFNP ++ L+EV+ S + S++ T +++ K+ G
Sbjct: 152 TEMSSRLKRPENALILHFFNPPYLLPLVEVVPSLYTSDEAKNTAVSLISRMKNHREGMVP 211
Query: 574 ITCKDTPGFVVNRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+ K+ GF+VNR+L P A + + G A+ EDID +K GAGFPMGP LAD
Sbjct: 212 VMAKEREGFIVNRLLIPLINSASDLLDSGVASAEDIDTAMKKGAGFPMGPLELAD 266
>UniRef50_Q47DJ5 Cluster: Enoyl-CoA
hydratase/isomerase:3-hydroxyacyl-CoA dehydrogenase, C-
terminal:3-hydroxyacyl-CoA dehydrogenase, NAD-binding;
n=1; Dechloromonas aromatica RCB|Rep: Enoyl-CoA
hydratase/isomerase:3-hydroxyacyl-CoA dehydrogenase, C-
terminal:3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Dechloromonas aromatica (strain RCB)
Length = 705
Score = 122 bits (293), Expect = 1e-26
Identities = 75/223 (33%), Positives = 122/223 (54%), Gaps = 2/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKI-EGFVKESLDRI 252
IA +A G V + D+ + L+ + +GR K G++ E ++ L I
Sbjct: 319 IAFTSALKGVPVRLKDISRQQLDLGMAEAKKQIGRQIKS------GRVSEAKGQQVLTSI 372
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
+ + DL++EAI+E L +K + ++L++ T++A+NTSS+ ++ I ++
Sbjct: 373 QPQLDYAGFSDCDLVVEAIIENLKVKHAVLSELEQAVAPDTVIASNTSSLRIDEIAMPLQ 432
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
R + F G+HFFNPVPVM L+EVIK S+ +++ ++GKT I +D PGF+VNR
Sbjct: 433 RPENFVGMHFFNPVPVMALVEVIKGSRTSDVAVSTAVDYAVTMGKTPIVVQDCPGFLVNR 492
Query: 613 ILXPYSAEALRMYERG-DATKEDIDIGLKLGAGFPMGPFXLAD 738
IL PY L + G D + ID +++ G+PMGP L D
Sbjct: 493 ILTPYVRAFLDLVADGVDFVR--IDRVMEV-FGWPMGPAYLMD 532
>UniRef50_O69856 Cluster: Fatty acid oxidation complex
alpha-subunit; n=6; Actinobacteria (class)|Rep: Fatty
acid oxidation complex alpha-subunit - Streptomyces
coelicolor
Length = 709
Score = 122 bits (293), Expect = 1e-26
Identities = 68/212 (32%), Positives = 112/212 (52%), Gaps = 2/212 (0%)
Frame = +1
Query: 109 VTIVDLEPEILNKAQKSIQANLGRVAKK--LYKDDPGKIEGFVKESLDRIKISTKVEDSV 282
V + D++ E ++K + A + ++ K + +D +++ V LD K E
Sbjct: 365 VVLTDIDQERVDKGVGYVHAEIDKLLGKGRVNQDKANRLKALVTGVLD------KAEGFA 418
Query: 283 NADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHF 462
+AD +IEA+ E++ +KQ +F +++ +AP H ILATNTSS+SV+ + S +K ++ G HF
Sbjct: 419 DADFVIEAVFEEMGVKQKVFAEVEAVAPAHAILATNTSSLSVSEMASKLKHPERVVGFHF 478
Query: 463 FNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRILXPYSAEAL 642
FNPV ++ LLE+++ + E K + KT + KD P FVVNRIL + E
Sbjct: 479 FNPVAILPLLEIVRGEQTDEAALATAFGVAKKLKKTAVLVKDAPAFVVNRILTRFMGEIQ 538
Query: 643 RMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+ + G T + G PM P L +
Sbjct: 539 NVIDEG--TPVAVAEKAVEPLGLPMSPLVLLE 568
>UniRef50_Q6D2L7 Cluster: Fatty acid oxidation complex subunit alpha
[Includes: Enoyl-CoA hydratase/3-hydroxybutyryl-CoA
epimerase (EC 4.2.1.17) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)]; n=16;
Gammaproteobacteria|Rep: Fatty acid oxidation complex
subunit alpha [Includes: Enoyl-CoA
hydratase/3-hydroxybutyryl-CoA epimerase (EC 4.2.1.17)
(EC 5.1.2.3); 3-hydroxyacyl-CoA dehydrogenase (EC
1.1.1.35)] - Erwinia carotovora subsp. atroseptica
(Pectobacterium atrosepticum)
Length = 731
Score = 122 bits (293), Expect = 1e-26
Identities = 83/223 (37%), Positives = 114/223 (51%), Gaps = 2/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQ-NVTIVDLEPEILNKAQK-SIQANLGRVAKKLYKDDPGKIEGFVKESLDR 249
IA VTA GQ V I D+ + +N A K + Q RV K K + +
Sbjct: 337 IASVTATRGQLPVRIKDINEQGINHALKYNWQLLTKRVQSKRMKPTERQ------RLMTL 390
Query: 250 IKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGI 429
I ST +AD++IEA+ E L +K+ + +++ A HTI A+NTSS+ ++ I G
Sbjct: 391 ISGSTDYRGFEHADIVIEAVFEDLALKRQMITEIEDHAAPHTIFASNTSSLPIHQIAEGA 450
Query: 430 KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVN 609
+R GLH+F+PV M L+EVI H S +T + + GKT I D+ GF VN
Sbjct: 451 RRPQLVVGLHYFSPVDKMPLVEVIPHAHTSAETVATTVALARKQGKTAIVVGDSAGFYVN 510
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
RIL PY EA G+ E ID L + GFP+GP L D
Sbjct: 511 RILAPYINEAAYCLLEGEPI-ESIDYAL-VRFGFPVGPLALLD 551
>UniRef50_Q8ZAN0 Cluster: Fatty acid oxidation complex subunit alpha
[Includes: Enoyl-CoA
hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA
isomerase/3- hydroxybutyryl-CoA epimerase (EC 4.2.1.17)
(EC 5.3.3.8) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)]; n=116; cellular
organisms|Rep: Fatty acid oxidation complex subunit
alpha [Includes: Enoyl-CoA
hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA
isomerase/3- hydroxybutyryl-CoA epimerase (EC 4.2.1.17)
(EC 5.3.3.8) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)] - Yersinia pestis
Length = 729
Score = 122 bits (293), Expect = 1e-26
Identities = 70/198 (35%), Positives = 107/198 (54%), Gaps = 2/198 (1%)
Frame = +1
Query: 151 QKSIQANLGRVAKKLYKD-DPGKIEGFVKES-LDRIKISTKVEDSVNADLIIEAIVEKLD 324
+ S+ + AK L K + GK++G S L I+ + A +I+EA+VE
Sbjct: 346 ENSLDLGMNEAAKLLNKQLERGKVDGLKMASILATIRPTLDYAGIERAQVIVEAVVENPK 405
Query: 325 IKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIK 504
+K + +++ L E T+LA+NTS+I ++ + +KR + F G+HFFNPV M L+E+I+
Sbjct: 406 VKAAVLAEVEALIGEDTVLASNTSTIPIDQLAKSLKRPENFCGMHFFNPVHRMPLVEIIR 465
Query: 505 SDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRILXPYSAEALRMYERGDATKEDID 684
S+ T A++ + +GKT I D PGF VNR+L PY A M R ID
Sbjct: 466 GAKTSDKTLAAVVAYATQMGKTPIVVNDCPGFFVNRVLFPYLA-GFGMLVRDGGDFHQID 524
Query: 685 IGLKLGAGFPMGPFXLAD 738
++ G+PMGP L D
Sbjct: 525 KVMEKQFGWPMGPAYLLD 542
>UniRef50_A0Z5J4 Cluster: Enoyl-CoA hydratase; n=2; unclassified
Gammaproteobacteria (miscellaneous)|Rep: Enoyl-CoA
hydratase - marine gamma proteobacterium HTCC2080
Length = 699
Score = 121 bits (291), Expect = 2e-26
Identities = 76/222 (34%), Positives = 114/222 (51%), Gaps = 1/222 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKES-LDRI 252
IA AQAG VT+VD+ E + + I N KK G++ ++ L I
Sbjct: 308 IAMCFAQAGIAVTLVDMTDEAVKGGLEKIAKNYAISVKK------GRLTVAQTDAILANI 361
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
S+ +D N D++IEA+ E L++K+++F KLD + +LA+NTS S++AI +
Sbjct: 362 TTSSSFDDLANVDMVIEAVFENLEVKKEVFGKLDVICKPGAVLASNTSYQSIDAIAAATS 421
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
R + G+HFF+P VM+LLEV+K S+ M GK +GK + GF+ NR
Sbjct: 422 RPESVLGMHFFSPANVMKLLEVVKGASSSDIVIATAMAVGKKIGKVSVLSGMCYGFIGNR 481
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+L Y EA G T ID ++ G MGP ++D
Sbjct: 482 MLRHYGREAALCLIEG-GTPAQIDSAME-SWGMAMGPLAVSD 521
>UniRef50_Q12AF3 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=40; cellular organisms|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 699
Score = 120 bits (290), Expect = 3e-26
Identities = 69/215 (32%), Positives = 120/215 (55%), Gaps = 1/215 (0%)
Frame = +1
Query: 97 AGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKI-EGFVKESLDRIKISTKVE 273
AG V I++++ E L++ +I+ N KK GK+ + ++ + + + +
Sbjct: 319 AGIPVKILEMKQEALDRGIATIRKNYESQVKK------GKLKQDKYEQRMSLLSTTLSYD 372
Query: 274 DSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKRKDKFGG 453
D +AD++IEA+ E++ +K+ + +LD++ ILA+NTS++ +N I S KR G
Sbjct: 373 DLKDADMVIEAVFEEMGVKEKVLKELDRVMKPGAILASNTSTLDMNQIASFTKRPQDVIG 432
Query: 454 LHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRILXPYSA 633
HFF+P VM+LLEV++ + ++D +M GK + KT + GF+ NR++ YS
Sbjct: 433 THFFSPANVMKLLEVVRGEKTAKDVLATVMALGKKIKKTAVVSGVCDGFIGNRMIEQYSR 492
Query: 634 EALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+A + E G AT +D ++ GF MGPF + D
Sbjct: 493 QAGFLLEEG-ATPAQVDKAVE-KFGFAMGPFRMGD 525
>UniRef50_A4YDR4 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=2; Sulfolobaceae|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Metallosphaera sedula DSM 5348
Length = 334
Score = 120 bits (290), Expect = 3e-26
Identities = 77/223 (34%), Positives = 125/223 (56%), Gaps = 1/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
I QV A AG VT+ D++ E L KA + I+ +L ++ +K G ++ V+ L RI
Sbjct: 15 IGQVFAMAGHEVTLYDVKEEALKKAMEGIRWSLQKLQEK------GSVKD-VESVLSRIF 67
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
S + ++ + L+IEA+ E + +K D+ ++ L E I+A+NTSS+ + + ++
Sbjct: 68 TSRDLSEARD-HLVIEAVFEDIKVKSDVLGRVSPLTDE--IIASNTSSLPITELSRAVRN 124
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITC-KDTPGFVVNR 612
++F G+HFFNP +M+L+EVI+ D+ SE+ ++ ++ KS+GK + KD GFVVNR
Sbjct: 125 PERFLGMHFFNPPVLMKLVEVIRGDNTSEERFREALDIVKSLGKYPLPVRKDVFGFVVNR 184
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLADY 741
IL A + + T +ID G PMG L DY
Sbjct: 185 ILFRLFTSACALLTQ--YTPHEIDYVAIKELGMPMGLIMLLDY 225
Score = 35.9 bits (79), Expect = 1.0
Identities = 24/81 (29%), Positives = 38/81 (46%)
Frame = +1
Query: 496 VIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRILXPYSAEALRMYERGDATKE 675
++KS + + Q +W K GK + K T G +L EA + +G T+E
Sbjct: 253 MVKSGKLGRKSGQGFYDWSK--GKPEV--KATSGPDPRELLRGAVEEAKWLISQGVVTRE 308
Query: 676 DIDIGLKLGAGFPMGPFXLAD 738
+++ GLKLG G G L +
Sbjct: 309 ELETGLKLGLGMSRGILELGE 329
>UniRef50_Q2W2Y1 Cluster: Glyoxysomal fatty acid beta-oxidation
multifunctional protein MFP-a; n=3;
Magnetospirillum|Rep: Glyoxysomal fatty acid
beta-oxidation multifunctional protein MFP-a -
Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)
Length = 703
Score = 120 bits (289), Expect = 4e-26
Identities = 79/222 (35%), Positives = 115/222 (51%), Gaps = 1/222 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKES-LDRI 252
IA A G VTI+D+ E L + I+ N R + G + ES + +
Sbjct: 309 IAMCFANIGIPVTIIDVSDENLQRGLGVIRKNYERSVSR------GSLTQEQLESRMGLL 362
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
ST +ADL IEA+ EK+++K+D+F KLD + P IL TNTS++ ++ I + K
Sbjct: 363 SASTDYAALKDADLAIEAVFEKMELKKDIFAKLDAVLPAGAILGTNTSTLDIDEIANTTK 422
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
R GLHFF+P VM LLE+++ + D ++ K + KT + K GF+ NR
Sbjct: 423 RPADVIGLHFFSPANVMPLLEIVQGKQTAMDVLLTALDMAKLIKKTGVVSKVCYGFIGNR 482
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
++ PY EA RM G AT +ID L+ G G MG + D
Sbjct: 483 MMDPYGREAERMVLEG-ATPAEIDGALE-GWGMAMGILAVYD 522
>UniRef50_A3ZYI9 Cluster: Fatty oxidation complex, alpha subunit
FadB; n=1; Blastopirellula marina DSM 3645|Rep: Fatty
oxidation complex, alpha subunit FadB - Blastopirellula
marina DSM 3645
Length = 724
Score = 120 bits (289), Expect = 4e-26
Identities = 73/223 (32%), Positives = 119/223 (53%), Gaps = 2/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IA + + G T+ D E L + + + + Y D GK + K
Sbjct: 332 IAAASIRRGILTTLSDANAEALRRGVAGV------LEEAAYDRDAGK-KTIAKAVEGAAM 384
Query: 256 ISTKVEDSVNA--DLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGI 429
++ + DS A L+IEAIVE L++K+ ++ +L+ + ILA+NTS++ + + + +
Sbjct: 385 LNASISDSEVAASKLVIEAIVENLEVKRKIYARLEPQLADDAILASNTSTLPITQLAANL 444
Query: 430 KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVN 609
+ ++F G+HFFNPV M+L+EVI+ S+ T + + + K +GK I D PGF+VN
Sbjct: 445 AKPERFVGIHFFNPVRKMKLVEVIRGAQTSDATVASAVAFAKRLGKFPIVVNDGPGFLVN 504
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
R+L PY EAL + + G + E +D K G P+GP L D
Sbjct: 505 RLLFPYMNEALALLQEG-VSMERVDKCAK-KFGMPLGPITLYD 545
>UniRef50_A1FD08 Cluster: 3-hydroxybutyryl-CoA epimerase; n=13;
cellular organisms|Rep: 3-hydroxybutyryl-CoA epimerase -
Pseudomonas putida W619
Length = 423
Score = 120 bits (289), Expect = 4e-26
Identities = 64/166 (38%), Positives = 96/166 (57%)
Frame = +1
Query: 241 LDRIKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIG 420
L R++ T + ADL+IEA+ E L +KQ++F LD ILA+NTS++ ++AI
Sbjct: 83 LARVRQVTAYTELAEADLVIEAVYENLALKQEIFRALDSTLKPEAILASNTSALDIDAIA 142
Query: 421 SGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGF 600
+ R ++ GLHFF+P VM+LLEV++ + A + G+ +GK + + PGF
Sbjct: 143 AVTGRPEQVLGLHFFSPAHVMKLLEVVRGQLTAPAVLDAAVALGQRMGKEVVVAGNCPGF 202
Query: 601 VVNRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+ NR+L Y AEA ++ G AT +D G G GF MGPF + D
Sbjct: 203 IGNRMLRTYVAEARQLLLEG-ATPRQVD-GALQGFGFAMGPFRMYD 246
>UniRef50_A7PEM6 Cluster: Chromosome chr11 scaffold_13, whole genome
shotgun sequence; n=3; core eudicotyledons|Rep:
Chromosome chr11 scaffold_13, whole genome shotgun
sequence - Vitis vinifera (Grape)
Length = 724
Score = 120 bits (289), Expect = 4e-26
Identities = 78/222 (35%), Positives = 118/222 (53%), Gaps = 5/222 (2%)
Frame = +1
Query: 88 TAQAGQNVTIV--DLEPEILNKAQKSIQANL-GRVAK-KLYKDDPGKIEGFVKESLDRIK 255
TA N+ +V ++ E L K K+I+AN+ G V K KL +D K +K LD +
Sbjct: 325 TALITSNIYVVLKEVNSEYLLKGIKTIEANVRGLVTKGKLTQDKARKALSMLKGVLDYSE 384
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
+ D++IEA++E + +KQ +F++++K+ H ILATNTS+I +N +G
Sbjct: 385 FK-------DIDMVIEAVIENISLKQKIFSEIEKICSPHCILATNTSTIDLNLVGEKTSS 437
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRI 615
+D+ G HFF+P VM LLEV++++ S +M GK++ K + GF VNR
Sbjct: 438 QDRIIGAHFFSPAHVMPLLEVVRTEKTSAQVILDLMTVGKAIKKIPVVVGSCTGFAVNRT 497
Query: 616 LXPYSAEALRMYERG-DATKEDIDIGLKLGAGFPMGPFXLAD 738
PY+ A + G D + D I G PMGPF L D
Sbjct: 498 FFPYAQGAHFLVNLGVDPFRIDWVIS---NFGLPMGPFQLQD 536
>UniRef50_Q9L6L5 Cluster: Fatty acid oxidation complex subunit alpha
[Includes: Enoyl-CoA
hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA
isomerase/3- hydroxybutyryl-CoA epimerase (EC 4.2.1.17)
(EC 5.3.3.8) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)]; n=42; Proteobacteria|Rep:
Fatty acid oxidation complex subunit alpha [Includes:
Enoyl-CoA
hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA
isomerase/3- hydroxybutyryl-CoA epimerase (EC 4.2.1.17)
(EC 5.3.3.8) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)] - Salmonella typhimurium
Length = 729
Score = 120 bits (289), Expect = 4e-26
Identities = 66/197 (33%), Positives = 108/197 (54%), Gaps = 2/197 (1%)
Frame = +1
Query: 154 KSIQANLGRVAKKLYKD-DPGKIEGF-VKESLDRIKISTKVEDSVNADLIIEAIVEKLDI 327
KS+ + AK L K + GKI+G + + I + D+++EA+VE +
Sbjct: 347 KSLNLGMTEAAKLLNKQLERGKIDGLKLAGVISTIHPTLDYAGFDRVDVVVEAVVENPKV 406
Query: 328 KQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKS 507
K+ + + ++ T+LA+NTS+I + + S ++R + F G+HFFNPV M L+E+I+
Sbjct: 407 KKAVLAETEQKVRPETVLASNTSTIPIGELASALERPENFCGMHFFNPVHRMPLVEIIRG 466
Query: 508 DHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRILXPYSAEALRMYERGDATKEDIDI 687
+ S++T ++ W +GKT I D PGF VNR+L PY A ++ G A +D
Sbjct: 467 EKSSDETIAKVVAWASKMGKTPIVVNDCPGFFVNRVLFPYFAGFSQLLRDG-ADFRKVDK 525
Query: 688 GLKLGAGFPMGPFXLAD 738
++ G+PMGP L D
Sbjct: 526 VMEKQFGWPMGPAYLLD 542
>UniRef50_Q5LVD0 Cluster: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase;
n=6; Rhodobacterales|Rep: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase -
Silicibacter pomeroyi
Length = 698
Score = 119 bits (286), Expect = 9e-26
Identities = 76/223 (34%), Positives = 119/223 (53%), Gaps = 2/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IA +G +VT++++ PE A+ I+ NL K+ GK+ ++L
Sbjct: 304 IATAALLSGLSVTMLEMTPEAAEAAKGRIEGNLSGALKR------GKLTAQQFDNLTTKA 357
Query: 256 ISTKVE-DSV-NADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGI 429
++ ++ D++ +ADL+IEA+ E +++K+ +F KLD + +LA+NTS + +N I +
Sbjct: 358 LTLAIDYDALADADLVIEAVFEDMEVKKQVFTKLDAVCKPGAVLASNTSYLDINQIAAVT 417
Query: 430 KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVN 609
R GLHFF+P VM+LLEV+ +D + D GK +GK + GF+ N
Sbjct: 418 SRPQDVLGLHFFSPAHVMKLLEVVIADQTAPDVAATGFALGKRLGKVSVRAGVCDGFIGN 477
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
RIL Y A M G A+ ID L+ GF MGPF +AD
Sbjct: 478 RILSVYRTCADHMILDG-ASPYQIDEALE-EFGFAMGPFAVAD 518
>UniRef50_Q0SCS0 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2;
Actinomycetales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Rhodococcus sp. (strain RHA1)
Length = 284
Score = 119 bits (286), Expect = 9e-26
Identities = 74/223 (33%), Positives = 113/223 (50%), Gaps = 2/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAK--KLYKDDPGKIEGFVKESLDR 249
IAQV A G V I + A K + L R + KL DP I G V
Sbjct: 21 IAQVFATLGSTVIIAESGDR--EAAVKRVSDGLDRAHERGKLGDVDPATILGRVST---- 74
Query: 250 IKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGI 429
+ + ++ DL++EA+ E +D+K + + ++K T++A+NTSSIS+ +GS +
Sbjct: 75 VAAPDALPPAL--DLVVEAVPELVDLKLSVLSLVEKTVSPTTVIASNTSSISIAELGSAL 132
Query: 430 KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVN 609
+ G+HFFNPVP L+E++++ + + EW +GKT + D+PGF +
Sbjct: 133 GDPARLIGMHFFNPVPASSLVEIVRAPATDAGVVEKVREWVAQLGKTEVLVNDSPGFATS 192
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
R+ EA+RM E G A E ID ++LG PMGP D
Sbjct: 193 RLGVCLGLEAIRMLEEGVADAESIDRAMELGYRHPMGPLRSTD 235
>UniRef50_A1SXV8 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Psychromonas|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Psychromonas ingrahamii
(strain 37)
Length = 724
Score = 119 bits (286), Expect = 9e-26
Identities = 71/210 (33%), Positives = 118/210 (56%)
Frame = +1
Query: 109 VTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIKISTKVEDSVNA 288
V + D+E + ++K ++ G++ KK++K + KI VK ++ I +
Sbjct: 350 VRLKDIEWDAVSKGYQTAALYYGQL-KKVHKINENKIR--VK--MNYIAGTVNYNGFKRI 404
Query: 289 DLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFN 468
DL++EA+ E L++K+ + +++ + ILA+NTSS+S+ + ++R + F G+HFFN
Sbjct: 405 DLVVEAVSENLEVKKTVLEEVEAQLSKQAILASNTSSLSITEMAVNLQRPENFIGMHFFN 464
Query: 469 PVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRILXPYSAEALRM 648
PV M L+E+I + S+ T +++ K GKT I + GF+VNRIL + EA M
Sbjct: 465 PVNRMPLVEIIPGEKTSQQTIVTLVKLAKKAGKTPIVVANCAGFLVNRILISFLNEAALM 524
Query: 649 YERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+ G E +D L+ G PMGPF LAD
Sbjct: 525 LQEGGVVTE-MDHALE-AFGLPMGPFVLAD 552
>UniRef50_A6WDS7 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=1; Kineococcus radiotolerans
SRS30216|Rep: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding - Kineococcus radiotolerans SRS30216
Length = 681
Score = 118 bits (285), Expect = 1e-25
Identities = 67/213 (31%), Positives = 113/213 (53%), Gaps = 2/213 (0%)
Frame = +1
Query: 109 VTIVDLEPEILNKAQKSIQANLGRVAKK--LYKDDPGKIEGFVKESLDRIKISTKVEDSV 282
V + D+ P+ + K ++ + + +K + D ++ V S+D+ ++
Sbjct: 345 VVLTDVSPDRVEKGVGFVREGVAELLRKGRVSPDTANRLSASVSGSVDKSALA------- 397
Query: 283 NADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHF 462
+AD ++EA+ E+L +KQD+ +L+ L ++ATNTSS+SV A+ S ++ +F G HF
Sbjct: 398 DADFVVEAVFEELAVKQDVLRELEPLLRPDAVIATNTSSLSVTAMASVLEHPQRFVGFHF 457
Query: 463 FNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRILXPYSAEAL 642
FNPV V+ L+EV+++ E + G + KTC+ +D P FVVNRI E +
Sbjct: 458 FNPVAVLPLVEVVRTPETDEASLATAFAVGARLKKTCVLVQDAPAFVVNRISTRMFDEVV 517
Query: 643 RMYERGDATKEDIDIGLKLGAGFPMGPFXLADY 741
R + G E ++ L G PM PF LA +
Sbjct: 518 RALDAGTPLLE-VERSLD-PLGLPMSPFRLASF 548
>UniRef50_A5N111 Cluster: Hbd2; n=5; Clostridiales|Rep: Hbd2 -
Clostridium kluyveri DSM 555
Length = 319
Score = 117 bits (281), Expect = 3e-25
Identities = 77/227 (33%), Positives = 121/227 (53%), Gaps = 6/227 (2%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFV-KESLDRI 252
I Q+ A++G NV + L + SI+ +L + +K GKI+ + KE L RI
Sbjct: 18 IVQLCAESGLNVNMFGRTDASLERGFTSIKTSLKNLEEK------GKIKTNISKEILKRI 71
Query: 253 KISTKVEDSVNA-DLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGI 429
K +E++V D +IE I E L++KQ++F+KLD++ ILA+NTS +S I
Sbjct: 72 KGVKTIEEAVEGVDFVIECIAEDLELKQEVFSKLDEICAPEVILASNTSGLSPTDIAINT 131
Query: 430 KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITC-KDTPGFVV 606
K ++ HF+NP + L+EV+ H T M+W + +GK + K+ GF+
Sbjct: 132 KHPERVVIAHFWNPPQFIPLVEVVPGKHTDSKTVDITMDWIEHIGKKGVKMRKECLGFIG 191
Query: 607 NRILXPYSAEALRMYERGDATKEDIDIGLKLGAG--FPM-GPFXLAD 738
NR+ EAL + E+G AT E++D ++ G G P+ GP AD
Sbjct: 192 NRLQLALLREALYIVEQGFATAEEVDKAIEYGHGRRLPVTGPICSAD 238
>UniRef50_Q1Z537 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Photobacterium profundum 3TCK|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Photobacterium profundum 3TCK
Length = 713
Score = 116 bits (280), Expect = 5e-25
Identities = 79/226 (34%), Positives = 123/226 (54%), Gaps = 5/226 (2%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEIL----NKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESL 243
IA VTA G +V + D+ L +A K + A + R KK + E+L
Sbjct: 327 IAYVTADKGADVVMKDINKAGLALGLTEANKLLAAQVERGRKKPLA---------MGETL 377
Query: 244 DRIKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGS 423
+RI+ + + + DLIIEA+VE IK+ + +L++++P T LA+NTS++ ++ +
Sbjct: 378 NRIQSTLYNQPLTSNDLIIEAVVENPKIKEAVLAELEQVSPNAT-LASNTSTLMISGLAQ 436
Query: 424 GIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFV 603
+K+ + F G+HFFNPV M L+EVI+ + S+ T +++ +GKT I D GF+
Sbjct: 437 ALKKPENFCGIHFFNPVHKMPLVEVIRGEQTSDQTITQAVKYVSQLGKTPIVVNDCAGFL 496
Query: 604 VNRILXPY-SAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
VNR L PY A + + GD ID + G G+PMGP L D
Sbjct: 497 VNRCLTPYFHAFNQLVVDGGDI--PTIDKVMSKGFGWPMGPAYLLD 540
>UniRef50_A5IDB6 Cluster: 3-hydroxyacyl CoA dehydrogenase; n=9;
Gammaproteobacteria|Rep: 3-hydroxyacyl CoA dehydrogenase
- Legionella pneumophila (strain Corby)
Length = 284
Score = 116 bits (280), Expect = 5e-25
Identities = 78/221 (35%), Positives = 111/221 (50%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
I Q+ AQ G VT++D L+KA+ +I NL +A + IE L I
Sbjct: 18 ITQLFAQYGFYVTLIDNLQSQLDKAKDTIAKNLHYLALTQNLESTHSIETI----LASIT 73
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
+TK+++ ++ IIE I E + K+ L+ L K IL NTSSI + I S +
Sbjct: 74 FTTKLDELKQSEYIIENITENWERKKALYQVLKKECSATCILGVNTSSIPITKIASLVDH 133
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRI 615
+ G+HF NP P+M ++EVIK H E T + + V K I KD+ GFV NR
Sbjct: 134 PQRVIGVHFMNPAPMMPMVEVIKGYHTDELTIEKTRTLLEQVHKKMIVVKDSVGFVSNRA 193
Query: 616 LXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+ + EA+ M + A+ EDID+ K G MGP AD
Sbjct: 194 MMIFINEAIFMVQENIASIEDIDVLFKQCFGHKMGPLHTAD 234
>UniRef50_P40939 Cluster: Trifunctional enzyme subunit alpha,
mitochondrial precursor (TP-alpha) (78 kDa
gastrin-binding protein) [Includes: Long-chain enoyl-CoA
hydratase (EC 4.2.1.17); Long chain 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.211)]; n=29; Eumetazoa|Rep:
Trifunctional enzyme subunit alpha, mitochondrial
precursor (TP-alpha) (78 kDa gastrin-binding protein)
[Includes: Long-chain enoyl-CoA hydratase (EC 4.2.1.17);
Long chain 3-hydroxyacyl-CoA dehydrogenase (EC
1.1.1.211)] - Homo sapiens (Human)
Length = 763
Score = 116 bits (280), Expect = 5e-25
Identities = 70/223 (31%), Positives = 114/223 (51%), Gaps = 2/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESL-DRI 252
IAQV+ G + D L++ Q+ + L KK + F ++S+ +
Sbjct: 376 IAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKK------ALTSFERDSIFSNL 429
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
+ AD++IEA+ E L +K + +++ + P+H I A+NTS++ ++ I + K
Sbjct: 430 TGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFASNTSALPISEIAAVSK 489
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
R +K G+H+F+PV M+LLE+I ++ S+DT + + G GK I KD PGF R
Sbjct: 490 RPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVGLKQGKVIIVVKDGPGFYTTR 549
Query: 613 ILXPYSAEALRMYERG-DATKEDIDIGLKLGAGFPMGPFXLAD 738
L P +E +R+ + G D K D L GFP+G L D
Sbjct: 550 CLAPMMSEVIRILQEGVDPKKLD---SLTTSFGFPVGAATLVD 589
>UniRef50_O29062 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 315
Score = 116 bits (278), Expect = 8e-25
Identities = 74/213 (34%), Positives = 118/213 (55%), Gaps = 3/213 (1%)
Frame = +1
Query: 79 AQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIKI 258
A + A G +V + D PE LN+A+ SI R L + G E VK +L R+K
Sbjct: 18 ASLFAWRGCDVAVYDPFPEALNRAEASI----ARTVSTLSEIFSGS-EDDVKSALSRVKF 72
Query: 259 STKVEDSVN-ADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGI-K 432
+ +E+++ A + E+ VEKL++K+DLF K+D +A TILAT+TS +S++ I + K
Sbjct: 73 TENLEEALKGAYYVQESAVEKLEVKRDLFEKMDAIAEPETILATSTSGLSISEIQTAARK 132
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITC-KDTPGFVVN 609
++ H +NP ++ L+EV+ E + +E+ + +GK I KD PG V N
Sbjct: 133 HPERCITAHPYNPPHLIPLVEVVPRKQTDESCTEKTVEFMERMGKKPIVVKKDVPGMVAN 192
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAG 708
R+ EA+ + +G AT E+ID+ +K G G
Sbjct: 193 RLAAALWREAVNLVYQGIATPEEIDVAVKYGPG 225
>UniRef50_Q2SGR6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Hahella chejuensis KCTC 2396|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Hahella chejuensis (strain KCTC 2396)
Length = 712
Score = 115 bits (277), Expect = 1e-24
Identities = 75/221 (33%), Positives = 109/221 (49%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IA A G VT+ D PE L +A K A L++D G + + DR+
Sbjct: 336 IAAWCALKGLRVTLQDQNPESLAEAYKH--------ANGLFRDKLGD-KRLAMVARDRLT 386
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
+ ADL++EAI EKL+ K+ L+ +++ LA+NTSSI ++ + G+
Sbjct: 387 PDPEGVGLAWADLVLEAIPEKLEAKRQLYQEIEPRMKSDATLASNTSSIPIDELARGLAH 446
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRI 615
++ GLHFFNPV M L+EVIK D S+ T M + + + PGF VNR+
Sbjct: 447 PERLVGLHFFNPVEKMLLVEVIKGDKTSQQTLDRAMAFAALIKRVPTPVNSAPGFFVNRV 506
Query: 616 LXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
L PY EA+ M++ G E +D + G MGP D
Sbjct: 507 LTPYLLEAMIMFDEG-VPAETLDAAAE-EFGMAMGPAETVD 545
>UniRef50_A1VP66 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Polaromonas naphthalenivorans CJ2|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Polaromonas naphthalenivorans (strain CJ2)
Length = 686
Score = 115 bits (277), Expect = 1e-24
Identities = 79/223 (35%), Positives = 113/223 (50%), Gaps = 2/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANL-GRVAKKLYKDDPGKIEGFVKE-SLDR 249
IA AG NV +++ + L + Q+ + + RVA GK++ V S R
Sbjct: 307 IAICALDAGLNVILLEQDDVALQRGQQRVAEHYQSRVAA-------GKVKAAVAAASQAR 359
Query: 250 IKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGI 429
+ +T ADL+IEA+ E + +KQD+F K+D A +LATNTS + V+AI
Sbjct: 360 LSPTTDWVQLGRADLVIEAVFEDMPVKQDVFRKIDAHARSGAVLATNTSYLDVDAIAQLT 419
Query: 430 KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVN 609
R GLHFF+P VM+LLEV++ + + D M GK + K + C + GF+ N
Sbjct: 420 ARPQDVLGLHFFSPANVMKLLEVVRGERTAADVVATGMALGKKLKKLPVLCGNAFGFIGN 479
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
I Y + M E G A E +D L GF MGPF +AD
Sbjct: 480 CIYNAYRKQCEFMLEDG-AWPEAVDQAL-TDLGFAMGPFAVAD 520
>UniRef50_A4RUY4 Cluster: Predicted protein; n=5; cellular
organisms|Rep: Predicted protein - Ostreococcus
lucimarinus CCE9901
Length = 722
Score = 115 bits (277), Expect = 1e-24
Identities = 69/222 (31%), Positives = 116/222 (52%), Gaps = 1/222 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKI-EGFVKESLDRI 252
IA AG V + +++ E L+ IQ+NL + +K G++ E ++ + +
Sbjct: 319 IATACLLAGIQVVLKEIKQEFLDAGVGRIQSNLTSMVRK------GRMTEDKARQLMSLV 372
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
K + +D D++IEA++E L +KQ +F +L+++ IL+TNTS+I + I + +K
Sbjct: 373 KPTLTDQDFRQCDMVIEAVIENLPLKQKIFCELERICKPDCILSTNTSTIDITKIAAKMK 432
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
++ G HFF+P VM+L E+I++D + K + KT + + GF VNR
Sbjct: 433 NPERIVGAHFFSPAHVMQLFEIIRTDATPAQILVDTLGLSKQIKKTPVVVGNCTGFAVNR 492
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
I PY+ A + + G ID + + G PMGPF L D
Sbjct: 493 IFFPYTMSATVLVDIG-CDPYAIDRAIMM-FGMPMGPFRLGD 532
>UniRef50_A3TT55 Cluster: Putative fatty acid oxidation complex
alpha subunit; n=3; Rhodobacterales|Rep: Putative fatty
acid oxidation complex alpha subunit - Oceanicola
batsensis HTCC2597
Length = 686
Score = 115 bits (276), Expect = 1e-24
Identities = 79/222 (35%), Positives = 112/222 (50%), Gaps = 1/222 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVK-ESLDRI 252
IA A G+ VTI D+ + L + R A ++Y D + G K ++LDR+
Sbjct: 332 IAAWAAMQGKRVTIEDVALDPLGETI--------RRATRVY--DGKHLSGIEKRDALDRL 381
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
ADL+IEA EK +K+D++ +L ILATNTSS+ + ++
Sbjct: 382 MPDPDRLGRARADLVIEAAPEKPGLKEDIYAELTDAMKPGAILATNTSSLPLASLVDAAP 441
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
+F GLHFFNPV M L+E++ D S +T + + + + D PGF+VNR
Sbjct: 442 DPARFAGLHFFNPVSKMPLVEIVSHDMASTETLDRLAAFTVGIDRLPARVTDYPGFLVNR 501
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
IL PY EA+ M + G K +ID L G PMGP LAD
Sbjct: 502 ILAPYMMEAMLMLDDGH-DKAEID-RAALAFGMPMGPVTLAD 541
>UniRef50_A6X670 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=1; Ochrobactrum anthropi ATCC 49188|Rep:
3-hydroxyacyl-CoA dehydrogenase NAD-binding -
Ochrobactrum anthropi (strain ATCC 49188 / DSM 6882 /
NCTC 12168)
Length = 659
Score = 114 bits (275), Expect = 2e-24
Identities = 61/164 (37%), Positives = 93/164 (56%)
Frame = +1
Query: 247 RIKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSG 426
++ +S + +ADL+IEA+ + +K LF +LD L P TILATNTS ++ + + +
Sbjct: 361 KLSVSADMAALADADLVIEAVFDDFTVKASLFRELDALLPPATILATNTSYLNPDELAAV 420
Query: 427 IKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVV 606
R D+ GLHFF+P +MRLLEV++ S++T + + + + K I GF+
Sbjct: 421 TNRTDRVLGLHFFSPANIMRLLEVVRCAETSDETLATGIAFARKIKKLSIVTGVCEGFIG 480
Query: 607 NRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
NR+ Y EA +M G A EDID ++ GFPMG F + D
Sbjct: 481 NRMFSAYRTEAEKMLAEG-AYPEDIDRAME-AYGFPMGLFAVYD 522
>UniRef50_A1SEZ9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Nocardioides sp. JS614|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Nocardioides sp. (strain BAA-499 /
JS614)
Length = 275
Score = 114 bits (275), Expect = 2e-24
Identities = 74/222 (33%), Positives = 114/222 (51%), Gaps = 1/222 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IA G VT+VD+ ++L++AQ + + R + D G +
Sbjct: 17 IAIAALATGFEVTLVDVAEDVLDRAQARVSEHFARHPQP----DRGVLH----------- 61
Query: 256 ISTKVEDSVN-ADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
+T + S+ A+++IEA+ E L +K +F +L + AP T+L +NTS++S++A+
Sbjct: 62 TTTSLAGSLETAEVVIEAVPEILPLKTQIFQQL-RGAPPGTLLVSNTSTMSISALAEACG 120
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
+ G+HFFNP M L+EV+ S+D + +GK I +D PGFV +R
Sbjct: 121 GSSRVVGMHFFNPAHRMPLVEVVVGTRTSDDARDRAVALAVRLGKDPIVVRDLPGFVTSR 180
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+ EA+RM E A DID L+LG G PMGP LAD
Sbjct: 181 LGLILGTEAMRMVEEQVANAADIDKALRLGYGHPMGPLELAD 222
>UniRef50_Q13I86 Cluster: 3-hydroxybutyryl-CoA epimerase; n=11;
Burkholderia|Rep: 3-hydroxybutyryl-CoA epimerase -
Burkholderia xenovorans (strain LB400)
Length = 714
Score = 114 bits (274), Expect = 2e-24
Identities = 73/223 (32%), Positives = 115/223 (51%), Gaps = 2/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKD-DPGKIEGFVKES-LDR 249
IAQV+A AG +V ++D + + + SI AK L + D G++ V++ L R
Sbjct: 328 IAQVSAAAGIDVVLLDRDLATAGRGRDSI-------AKALQAEVDKGRLREAVRDQILSR 380
Query: 250 IKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGI 429
I+++ N DL+IEA++E ++K + + P H I A+NTS++ +N + S
Sbjct: 381 IEVAADHSAFGNCDLVIEAVLEDFEVKASVTRATEAALPAHAIFASNTSALPINELASAS 440
Query: 430 KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVN 609
R F GLHFF+PV M L+EVI S++T +++ + + KT I +D GF
Sbjct: 441 ARPQNFIGLHFFSPVSRMALVEVIVGSATSDETLARSLDYIQQIHKTPIVVRDGYGFYTT 500
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
R + Y E +R+ G + G L G P+GP LAD
Sbjct: 501 RCVEAYIREGVRLLADGVNPVLIENAGTAL--GMPVGPLTLAD 541
>UniRef50_A3T2M8 Cluster: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase;
n=4; cellular organisms|Rep: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase -
Sulfitobacter sp. NAS-14.1
Length = 695
Score = 114 bits (274), Expect = 2e-24
Identities = 72/222 (32%), Positives = 112/222 (50%), Gaps = 1/222 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGR-VAKKLYKDDPGKIEGFVKESLDRI 252
IA A AG +VT+V+ A K++Q + + +++ + D K DR+
Sbjct: 301 IAYTLATAGISVTVVERSASSAEWASKNLQKLIDQGISRGILSVDAAKTVE------DRL 354
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
+ + DL IEA E +K + +L+ P TI+ATNTS + VN + G+K
Sbjct: 355 VTVSGYDALPPTDLAIEAAFEDFAVKTAILTELEGALPPETIIATNTSYLDVNRLSDGLK 414
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
+F G+HFF+P +M+LLEV++SD S+ T A + +GK + GF+ NR
Sbjct: 415 HPARFVGMHFFSPAHIMKLLEVVRSDRTSDGTLGAALVLAHRLGKIPVLSGVCDGFIGNR 474
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
IL Y A R+ G A ++ID ++ G G MGP+ D
Sbjct: 475 ILSSYRRAANRLLVEG-ANVDEIDAAMR-GFGMAMGPYAAQD 514
>UniRef50_Q89SH2 Cluster: Blr2428 protein; n=7; Rhizobiales|Rep:
Blr2428 protein - Bradyrhizobium japonicum
Length = 715
Score = 113 bits (272), Expect = 4e-24
Identities = 75/221 (33%), Positives = 117/221 (52%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IA A G V++ D++ E + A K G++ +K P + V+++LDR+
Sbjct: 355 IAAWCAGQGLRVSLADMKAEPIAGAVKRAAELYGKIIRK-----PTE----VRDALDRLI 405
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
E NADL+IEA+ EKL++KQ ++ L+ ILATNTSSI + + + + R
Sbjct: 406 PDMDGEGVRNADLVIEAVPEKLELKQKVYAGLEPKMKPGAILATNTSSIPLQDLRTTLAR 465
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRI 615
D+ GLHFFNPV ++L+EV+ D + + + ++ + + K +PGF+VNR
Sbjct: 466 PDRLVGLHFFNPVSRLQLVEVVSHDGNDAQVLREALAFVGAIDRLPLAVKSSPGFLVNRA 525
Query: 616 LXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
L Y EA+ M + + ID + G PMGP LAD
Sbjct: 526 LTLYMLEAMVMLDE-KIDQRLIDAAAE-QFGMPMGPIELAD 564
>UniRef50_A0LI43 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Syntrophobacter fumaroxidans MPOB|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
Length = 681
Score = 112 bits (269), Expect = 1e-23
Identities = 66/209 (31%), Positives = 109/209 (52%), Gaps = 1/209 (0%)
Frame = +1
Query: 109 VTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKI-EGFVKESLDRIKISTKVEDSVN 285
V + D+ PE L K + R+ +K GK+ EG + + + D +
Sbjct: 343 VVMKDISPEALEKGCGQVVEGFRRLGEK------GKLTEGKARHLAGLVSGTLDFRDFSD 396
Query: 286 ADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFF 465
D +IEA+ E++ +K+ + +L+ L ++ATNTSS+SV + S ++ + G HFF
Sbjct: 397 CDFVIEAVFEEMAVKKQVLGELEPLLRPDAVIATNTSSLSVTEMASVLRVPGRMLGFHFF 456
Query: 466 NPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRILXPYSAEALR 645
NPV V+ L+EVI++ S + + + + KT + KD P F+VNRIL + L
Sbjct: 457 NPVAVLPLVEVIRTAQTSGEALATAFDLARKLRKTGVLVKDAPAFLVNRILVKMLVDCLA 516
Query: 646 MYERGDATKEDIDIGLKLGAGFPMGPFXL 732
+ + G A+ +++D L L G PM PF L
Sbjct: 517 LVDEG-ASFQEVDDAL-LALGLPMAPFDL 543
>UniRef50_A7HHZ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=3; Bacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase NAD-binding - Anaeromyxobacter sp. Fw109-5
Length = 723
Score = 111 bits (267), Expect = 2e-23
Identities = 76/221 (34%), Positives = 112/221 (50%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
I+ VTA AG V I + + KA S++A L K+ D ++E E + +
Sbjct: 343 ISFVTANAGIPVRIRERDDAAAGKALGSVRALLDERVKRRSID---RLER--DERMRLVT 397
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
+T D++IEA+ E L +KQ++ + + P I A+NTSSI + I
Sbjct: 398 ATTDWSGYAAVDVLIEAVFEDLALKQEMVRAFEAVNPTG-IFASNTSSIPITKIAEASAH 456
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRI 615
+ G+H+F+PV M LLE+I ++ S++ + GK GKT I D PGF +RI
Sbjct: 457 PETVLGMHYFSPVQKMPLLEIIVTEKTSKEATATAVALGKKQGKTVIVVGDGPGFYTSRI 516
Query: 616 LXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
L PY EA + G A ED+D L + GFP+GP L D
Sbjct: 517 LAPYMNEAAELLVEG-AAVEDLDRAL-VEFGFPVGPITLLD 555
>UniRef50_A4BL13 Cluster: Fatty oxidation complex, alpha subunit;
n=3; Proteobacteria|Rep: Fatty oxidation complex, alpha
subunit - Nitrococcus mobilis Nb-231
Length = 726
Score = 111 bits (267), Expect = 2e-23
Identities = 73/216 (33%), Positives = 113/216 (52%)
Frame = +1
Query: 91 AQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIKISTKV 270
A+A V + D+EP+ L K I R+ ++L + + E + + R+ +
Sbjct: 350 ARAKVPVRLKDVEPKGLASGLKYIDE---RIDQRLSRHAISRFEA--ERARCRVTPTLDF 404
Query: 271 EDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKRKDKFG 450
+ DL+IEA+ E L++K + +++ I A+NTSS+ + I +R
Sbjct: 405 SGCRSLDLVIEAVFEDLELKHRMIREVEANCNADVIFASNTSSLPLARIAQAAERPQNVI 464
Query: 451 GLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRILXPYS 630
GLH+F+PV M LLEVI + + + M +G++ GKT I +D GF VNRIL PY
Sbjct: 465 GLHYFSPVDRMPLLEVIAHERTAPEVIATAMAFGRAQGKTPIVVRDGVGFYVNRILAPYL 524
Query: 631 AEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
EA+ + E G A + ID L + GFP+GPF L D
Sbjct: 525 NEAVHLLEEGVAI-DRIDQAL-VRFGFPVGPFKLLD 558
>UniRef50_Q0SEM1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 286
Score = 111 bits (266), Expect = 2e-23
Identities = 69/221 (31%), Positives = 117/221 (52%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
+A+ AQAG +V +VD +P+ +++A+ ++ +L R+A L + K E R+
Sbjct: 21 VAECLAQAGHDVIVVDPDPQAVDQARSRMRDSL-RLAILLGRAGGPK----PAEVTARVH 75
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
+ ++ D +A ++IE + E++D+K+ +F +LD++ +LA+ TS I V+ + R
Sbjct: 76 WTGEMTDLRDAAVVIECVPERIDLKEKVFAELDRVCAPDALLASCTSGIPVDRLADTTTR 135
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRI 615
++ GLHF NP P+ +EV++ S + + S+ KT I D PGF++NR+
Sbjct: 136 PERVVGLHFMNPAPLKDTVEVVRGPRTSPQSLDRALALLASLNKTGIVVGDGPGFLLNRV 195
Query: 616 LXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
L AEA G A E D + G PMGP AD
Sbjct: 196 LMLCIAEAAAALGDGIADAETTDALFEGCLGHPMGPLRTAD 236
>UniRef50_A1FNB9 Cluster: 3-hydroxyacyl-CoA dehydrogenase precursor;
n=4; Proteobacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase
precursor - Pseudomonas putida W619
Length = 313
Score = 111 bits (266), Expect = 2e-23
Identities = 76/228 (33%), Positives = 124/228 (54%), Gaps = 7/228 (3%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IAQV AQAG V++ D + L+ A + + NL D G + L I
Sbjct: 19 IAQVFAQAGHKVSLYDPDAATLDLAPQRVAHNL---------DQMGIASAPI---LANIA 66
Query: 256 ISTKVEDSV-NADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGS--G 426
+ T + ++V NAD++IEA+ E+L++KQ LF + AP HT+LA+NTS I + IG G
Sbjct: 67 LFTDLREAVSNADIVIEAVPERLELKQKLFADIAGFAPPHTVLASNTSVIPITEIGEMLG 126
Query: 427 IKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITC-KDTPGFV 603
+ + + G H++NP ++ L+EV++++H S +++ E +S+GK+ + +D GF+
Sbjct: 127 SEARARLVGTHWWNPPHLVPLVEVVRTEHTSLSVFESTFELLQSLGKSPVKVNRDVAGFI 186
Query: 604 VNRILXPYSAEALRMYERGDATKEDIDIGLK--LGAGFP-MGPFXLAD 738
NR+ EA+ + +G E ID +K G P +GP AD
Sbjct: 187 GNRLQHAMWREAISLVSQGVCDAETIDTVVKQSFGMRLPYLGPMENAD 234
>UniRef50_Q3KCL0 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Pseudomonas fluorescens PfO-1|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Pseudomonas fluorescens (strain PfO-1)
Length = 703
Score = 110 bits (265), Expect = 3e-23
Identities = 69/222 (31%), Positives = 116/222 (52%), Gaps = 1/222 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGF-VKESLDRI 252
IA A G V ++DL+ L++ K ++ N K+ GK+ +++ ++ +
Sbjct: 313 IAMSFADVGIPVALMDLDGRTLDRGLKRVRENYQLSVKR------GKLSAVQMQQRMELL 366
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
+ D +ADLIIEA+ EK++ K +F L+ + ILATNTSS+ ++A+ +
Sbjct: 367 FGTLDYADLSDADLIIEAVCEKMESKHQVFLALESVCKPGAILATNTSSLDIDALAKMVS 426
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
R G+HFF+P VMRL+E++ + D A+M+ + +GK + ++ G + NR
Sbjct: 427 RPQDVIGMHFFSPANVMRLVEIVLCQTTAPDVVTAVMDIARRIGKLPVISGNSAGSIGNR 486
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+L PY+ EA R+ G AT +D L MG F + D
Sbjct: 487 MLEPYAREAHRLVLEG-ATPVQVDAVL-TSLDLNMGVFSMLD 526
>UniRef50_Q1GGC1 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=4; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase NAD-binding -
Silicibacter sp. (strain TM1040)
Length = 733
Score = 110 bits (265), Expect = 3e-23
Identities = 70/221 (31%), Positives = 111/221 (50%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IA V+AQAG V ++D + + +K K+ A K K P K E L +I
Sbjct: 341 IALVSAQAGMEVVLIDRDQDAADKG-KAYSATYMDKGIKRGKATPEKKEAL----LAQIT 395
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
+ ++ DLIIEA+ E +K ++ K++ + PE I A+NTS++ + ++ R
Sbjct: 396 ATADLDALKGCDLIIEAVFEDPGVKAEMTKKVEAIIPEDCIFASNTSTLPITSLAEASVR 455
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRI 615
++F G+HFF+PV M L+E+IK + + +++ + + KT I D F NR
Sbjct: 456 PEQFIGIHFFSPVEKMFLVEIIKGEKTGDRAVAKALDYVRQIRKTPIVVNDARFFYCNRC 515
Query: 616 LXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+ PY E RM G + ID + GFP+GP L D
Sbjct: 516 IIPYINEGARMITEG-VSPVLIDNAAR-QLGFPVGPIQLTD 554
>UniRef50_Q83DW6 Cluster: Fatty oxidation complex, alpha subunit;
n=9; Gammaproteobacteria|Rep: Fatty oxidation complex,
alpha subunit - Coxiella burnetii
Length = 642
Score = 109 bits (262), Expect = 7e-23
Identities = 74/221 (33%), Positives = 112/221 (50%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IA A G VT+ D E + A K A KKL KI ++ ++DR++
Sbjct: 288 IAAWCALRGIRVTLHDKSAEKIAPAIKRAHA---LYEKKL------KIPRLIQAAMDRLE 338
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
+ ADLIIEA+ E + +KQ++ + ++ ILATNTSS+S++ + S +K
Sbjct: 339 PDVEGTGVKKADLIIEAVFEDIKVKQEVLSAIEPQLKPEAILATNTSSLSLDELSSVLKN 398
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRI 615
++ +HFFNPV + L+EV S S D + + + ++ K + +PGF+VNR
Sbjct: 399 PERLVAIHFFNPVAKLPLVEVASSQQTSADIAEKALAFVGAIDKLPLAVSSSPGFLVNRA 458
Query: 616 LXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
L Y EA R + G + E ID G P+GP LAD
Sbjct: 459 LMAYLLEANRCLDEG-FSMEQID-KAATDFGMPIGPIELAD 497
>UniRef50_Q5P039 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
Proteobacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum
(strain EbN1))
Length = 443
Score = 109 bits (262), Expect = 7e-23
Identities = 67/222 (30%), Positives = 111/222 (50%), Gaps = 1/222 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKES-LDRI 252
IA A G VT+ D + L + + ++ N + G+++ + L I
Sbjct: 56 IAMSFANVGIPVTVCDTDGAALERGLERVRRNYEFSVAR------GRLDAATMAARLALI 109
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
+ + ++D +ADL+IEA+ E + +KQD+F KLD + ILATNTS + ++ I +
Sbjct: 110 RAAVDLQDLKDADLVIEAVFEDMALKQDIFRKLDAIVHPDAILATNTSGLDIDEIAVVTR 169
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
R G HFF+P V +LLEV++ + + +M G+ +GK + + PGF+ N
Sbjct: 170 RPQDVVGAHFFSPAHVQKLLEVVRGARTAPEVIATLMSLGRRMGKVSVLSRIYPGFIGNA 229
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+ Y EA + E G A ++D L G+ MG F + D
Sbjct: 230 LFRQYVREAHFLVEEG-ALPHEVDSALG-RFGYAMGVFAVHD 269
>UniRef50_Q1YTH7 Cluster: Fatty oxidation complex, alpha subunit;
n=4; Gammaproteobacteria|Rep: Fatty oxidation complex,
alpha subunit - gamma proteobacterium HTCC2207
Length = 718
Score = 108 bits (260), Expect = 1e-22
Identities = 68/223 (30%), Positives = 114/223 (51%), Gaps = 2/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAK--KLYKDDPGKIEGFVKESLDR 249
IA A G +V + D+ L+ + L + K KL ++ G+I +K SL+
Sbjct: 332 IAYQNAIRGYSVVMKDINQPALDLGIQEANKLLAKGVKRGKLTEEKAGQILSLIKPSLED 391
Query: 250 IKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGI 429
D ++++EA+VE +K+ + ++ L ++ +NTS+IS+N + +
Sbjct: 392 -------SDVAPCNMLVEAVVELESVKKMVLPAVEALLDNSAVITSNTSTISINRLAESL 444
Query: 430 KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVN 609
+R F G+HFFNPV M L+E+I+ ++ S++T A+ + +GK I D PGF+VN
Sbjct: 445 ERPQNFCGMHFFNPVHAMPLVEIIRGENTSDETIAAVCAYALGLGKKPIVVNDCPGFLVN 504
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
R+L M G A + +D ++ G G PMGP L D
Sbjct: 505 RVLFAMLFGLEIMISEG-ADFQQVDKVME-GWGLPMGPAYLMD 545
>UniRef50_Q1D1F2 Cluster: Fatty oxidation complex, alpha subunit FadJ;
n=2; Cystobacterineae|Rep: Fatty oxidation complex, alpha
subunit FadJ - Myxococcus xanthus (strain DK 1622)
Length = 746
Score = 108 bits (260), Expect = 1e-22
Identities = 73/222 (32%), Positives = 113/222 (50%), Gaps = 1/222 (0%)
Frame = +1
Query: 76 IAQVTAQA-GQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRI 252
IA VT+ G V + D + + +A K +Q+ L K+ + E K +L +
Sbjct: 364 IAYVTSVLQGVPVRVKDKDDAGVGRAMKQVQSILDERVKRRSLT---RREATAKSAL--V 418
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
T +ADL+IEA+ E L +K + +++ + + TI A+NTSSI + + G +
Sbjct: 419 TAGTDYSGFKSADLVIEAVFEDLKLKHRIIAEVEAVTGDQTIFASNTSSIPITELAKGSR 478
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
R + G+H+F+PV M LLE+I ++ +E G+ GKT I D PGF +R
Sbjct: 479 RPAQVIGMHYFSPVHKMPLLEIITHAGTADWVTATCVEVGRKQGKTVIVVNDGPGFYTSR 538
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
IL PY EA + G A ++D L + GFP+GP L D
Sbjct: 539 ILAPYMNEAAYLLAEG-ADIAELDRAL-VEFGFPVGPITLLD 578
>UniRef50_A4BGI3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Reinekea sp. MED297|Rep: 3-hydroxyacyl-CoA dehydrogenase
- Reinekea sp. MED297
Length = 705
Score = 108 bits (260), Expect = 1e-22
Identities = 67/221 (30%), Positives = 114/221 (51%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IA A G V +VD E ++A++ + VAK+ + EG L+RI
Sbjct: 328 IAWACASKGLPVVLVDTEQ---SRAEQGKGYSERLVAKRFERGRLSAEEGTAL--LNRIT 382
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
+ + + DL+IEA+ E +K D++ + + TI+A+NTS++ ++++ + R
Sbjct: 383 PTESMSELAECDLVIEAVFEDRALKADVYQLIQSVVSPETIIASNTSTLPISSLAGMVDR 442
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRI 615
D+F GLHFF+PV M LLE+I+ + S+ T A + + + KT I D GF +R+
Sbjct: 443 PDQFIGLHFFSPVDKMPLLEIIRGEQTSKSTVNAALAFSHQITKTPIVVNDGRGFYTSRV 502
Query: 616 LXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
++ E + M G I+ L AG+P+GP ++D
Sbjct: 503 FKQFTYEGMAMLAEG-VPAAAIENAAWL-AGYPVGPLAVSD 541
>UniRef50_Q1IMY8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Acidobacteria bacterium Ellin345|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Acidobacteria bacterium (strain Ellin345)
Length = 278
Score = 108 bits (259), Expect = 2e-22
Identities = 69/223 (30%), Positives = 117/223 (52%), Gaps = 2/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKES-LDRI 252
IAQ A G + D+ P L KA+ +I+A LGR G +E ++ L RI
Sbjct: 19 IAQAAAVGGFRTILEDILPNALRKAEDAIRAELGRAVST------GSVEQREADAALARI 72
Query: 253 KISTKVEDSV-NADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGI 429
+ ++ +ED+ +AD++IEA+ ++L+ K ++F LDK+ T++ ++T S+ + S I
Sbjct: 73 EYASNLEDAARDADMVIEAVPDELESKLEIFVLLDKVCRPETMIVSHTQIQSITELASVI 132
Query: 430 KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVN 609
R K + F P LE+++ S++T A + + + + I ++TPG +
Sbjct: 133 YRAPKCIAMWFPKPPQTSVALEIVRGLETSDETATAAVAVAQRMKREPILLRETPGAITA 192
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
R+ S EA +M G A+ E+ID L+ G G PMGP A+
Sbjct: 193 RMQALISNEAFKMLGEGLASAEEIDRALQQGLGLPMGPIAEAE 235
>UniRef50_A0JVH8 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=12; Actinomycetales|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Arthrobacter sp. (strain FB24)
Length = 723
Score = 108 bits (259), Expect = 2e-22
Identities = 64/210 (30%), Positives = 108/210 (51%), Gaps = 2/210 (0%)
Frame = +1
Query: 109 VTIVDLEPEILNKAQKSIQANLGRVA--KKLYKDDPGKIEGFVKESLDRIKISTKVEDSV 282
V + D++ ++K + A + ++ K++ D + + V S+ + +
Sbjct: 375 VVMTDIDQARVDKGVGYVHAEVDKMLAKKRISADAANRTKALVTGSVSK-------DAFA 427
Query: 283 NADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHF 462
+AD +IEA+ E+L++K+ +F +++ + ILATNTSS+SV A+ + + ++ G HF
Sbjct: 428 DADFVIEAVFEELNVKKQVFAEVEAIVSPECILATNTSSLSVTAMAADLAHPERLVGFHF 487
Query: 463 FNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRILXPYSAEAL 642
FNPV VM LLE++++ + E K + KT + KD FVVNRIL E
Sbjct: 488 FNPVAVMPLLEIVRAPKTDDAVLATAFELAKGLKKTAVLVKDAAAFVVNRILLRLMGEVT 547
Query: 643 RMYERGDATKEDIDIGLKLGAGFPMGPFXL 732
++ G E D L+ G PM PF L
Sbjct: 548 AAFDEG-TPAEVADNALR-PMGLPMTPFTL 575
>UniRef50_UPI0000E4974C Cluster: PREDICTED: hypothetical protein;
n=3; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 953
Score = 107 bits (258), Expect = 2e-22
Identities = 64/222 (28%), Positives = 113/222 (50%), Gaps = 1/222 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKI-EGFVKESLDRI 252
I AG + + + L+K K +Q L K+ G++ E ++ +
Sbjct: 341 ITMSMVMAGIPTYLTEQNQQYLDKGLKMVQGILAHWVKQ------GRMSEAKAQQIFSLV 394
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
+ + +D + D+++EA+ E + +K+++ LD + ILA+NTS++ ++ + S
Sbjct: 395 RPTLTYDDLKDVDVVVEAVFENMALKKEILKTLDGVCKPSAILASNTSTLDIDEMASATT 454
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
R DK G+HFF+P +M+LLE ++ S +T M+ GK + K + + P FV NR
Sbjct: 455 RPDKVMGMHFFSPAHIMKLLENVRGKDTSPETMATAMDLGKRMKKISVLVGNCPAFVGNR 514
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+L PYS EA+ + E G A ++D L+ G MG + D
Sbjct: 515 MLAPYSREAIFLLEEG-ALPNEVDQVLE-DFGLAMGLCRMGD 554
>UniRef50_Q3JZL6 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putative;
n=7; Streptococcus agalactiae|Rep: 3-hydroxyacyl-CoA
dehydrogenase, putative - Streptococcus agalactiae
serotype Ia
Length = 377
Score = 107 bits (258), Expect = 2e-22
Identities = 79/251 (31%), Positives = 125/251 (49%), Gaps = 30/251 (11%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRV-------AKKLYKDDPGKIE---- 222
IA A G +VTI D+ E LNK ++ I+ L +V AK+ Y D I+
Sbjct: 74 IAFQAAYKGMSVTIYDINDEALNKGKERIK-KLAKVYQSEIETAKEAYSDKAKSIKYNKN 132
Query: 223 ----------GFVKESLD-------RIKISTKVEDSVN-ADLIIEAIVEKLDIKQDLFNK 348
V +SLD +I S ++ +V+ ADL+IEA+ E + IK+D + +
Sbjct: 133 LLPSLDHIFLSKVADSLDLIADLPNQITFSKNLDQAVSDADLVIEAVPETVSIKEDFYKQ 192
Query: 349 LDKLAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDT 528
L K+AP TI ATN+S++ + R DKF +HF N + ++E++ ++
Sbjct: 193 LAKVAPSKTIFATNSSTLVPSQFADITGRPDKFLAMHFANNIWQNNIVEIMGHKGTDDEV 252
Query: 529 YQAMMEWGKSVGKTCITC-KDTPGFVVNRILXPYSAEALRMYERGDATKEDIDIGLKLGA 705
+ + + K +G + K+ PG+++N IL P+ AL +Y + E ID KLG
Sbjct: 253 IKEALTFSKDIGMVPLHIHKEQPGYILNSILVPFLESALALYYDKVSDSETIDKTWKLGT 312
Query: 706 GFPMGPFXLAD 738
G PMGP + D
Sbjct: 313 GAPMGPLEILD 323
>UniRef50_A5WEP3 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=7; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Psychrobacter sp. PRwf-1
Length = 723
Score = 107 bits (258), Expect = 2e-22
Identities = 67/221 (30%), Positives = 108/221 (48%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IA V+A+AG +V ++D E K + L + + + K + LD+I
Sbjct: 337 IAYVSAKAGIDVVLLDTSIEAAEKGKDYSSKLLDKAIARGRSTEQKK-----QALLDKIN 391
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
+T +D + DLIIEA+ E +DIK + + E I A+NTS++ + + KR
Sbjct: 392 TTTAYDDLEDCDLIIEAVFEDIDIKAACTRNTEAVIAETAIYASNTSTLPITELAKASKR 451
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRI 615
++F GLHFF+PV M L+E+I + + T ++ + KT I D+ GF +R+
Sbjct: 452 PNQFIGLHFFSPVDKMPLVEIIVGEETDDATLAKGFDYVGQIAKTPIVVNDSRGFYTSRV 511
Query: 616 LXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
Y +E + M G + G+K +G PM P L D
Sbjct: 512 FGTYVSEGIAMLSEGIHPRSIEVAGMK--SGMPMPPLALQD 550
>UniRef50_A4SW27 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7;
Burkholderiales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Polynucleobacter sp. QLW-P1DMWA-1
Length = 313
Score = 107 bits (258), Expect = 2e-22
Identities = 56/147 (38%), Positives = 84/147 (57%), Gaps = 1/147 (0%)
Frame = +1
Query: 274 DSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKRKDKFGG 453
D + DL+IE + E+LDIKQ+LF KL+K A +LA+N++S ++ I SG+K + G
Sbjct: 76 DWADVDLVIECVPERLDIKQELFAKLEKYAKPEAVLASNSTSFPISEIASGLKTAARMIG 135
Query: 454 LHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITC-KDTPGFVVNRILXPYS 630
LHFF P ++ +EV+ + S ++ + G +T KD PGF+ NR+ S
Sbjct: 136 LHFFMPAHLVPCVEVVYGEKTSPMVGDSLSRLMTACGMVPVTVKKDLPGFLANRLQHALS 195
Query: 631 AEALRMYERGDATKEDIDIGLKLGAGF 711
EA M + G T EDID ++ G GF
Sbjct: 196 REAFAMVDAGICTPEDIDKAVRFGFGF 222
>UniRef50_A1IDF2 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerase family protein precursor; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep:
3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerase family protein precursor -
Candidatus Desulfococcus oleovorans Hxd3
Length = 801
Score = 107 bits (258), Expect = 2e-22
Identities = 70/207 (33%), Positives = 102/207 (49%), Gaps = 8/207 (3%)
Frame = +1
Query: 19 LSHALKXXXXXXXXXXXXXIAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLY 198
+S +K IA + A AG ++D+ P L QK A R+ K Y
Sbjct: 1 MSRKIKKAAVIGSGVMGGGIAALLASAGVETLLLDIVPFDLTDEQKKDPAARNRIVKFGY 60
Query: 199 KDDPGKIEGFVKESLDRIKIST-KVEDS----VNADLIIEAIVEKLDIKQDLFNKLDKLA 363
+ S D IS +ED + D I+E +VE L IKQ LF +++ +
Sbjct: 61 DTIMMSRPAALMHSSDAALISIGNLEDDFDKLADCDWIVEVVVENLKIKQQLFKRIEPVR 120
Query: 364 PEHTILATNTSSISVNAIGSGIKR--KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQA 537
+ +I+++NTS I + A+ G+ K F G HFFNPV M LLE+IK + SE+ +
Sbjct: 121 KKGSIISSNTSGIPLKAMSEGLSSDFKQHFLGTHFFNPVRYMHLLEIIKGEETSEEVLRF 180
Query: 538 MMEWG-KSVGKTCITCKDTPGFVVNRI 615
M +G K +GK + KDTP F+ NRI
Sbjct: 181 MAAFGEKRLGKGIVWAKDTPNFIGNRI 207
>UniRef50_Q11BV6 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Mesorhizobium sp. BNC1|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Mesorhizobium sp. (strain BNC1)
Length = 677
Score = 107 bits (256), Expect = 4e-22
Identities = 64/214 (29%), Positives = 108/214 (50%)
Frame = +1
Query: 97 AGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIKISTKVED 276
AG++V ++D + L +A ++++ L R+ + GK++ +L R+ S ++
Sbjct: 307 AGKSVVLIDKDDLALTRASAAVKSGLARLERG------GKLKEAPDAALARLVASKELSA 360
Query: 277 SVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKRKDKFGGL 456
N +++IEA+VE ++K + + L ++ +NTS + + + R D+F GL
Sbjct: 361 VENCEVVIEAVVESFEVKSAVLSDLHARLSPGAMVVSNTSYLDIAELARASGRPDRFLGL 420
Query: 457 HFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRILXPYSAE 636
HFF PVPVM L+EV+ S T + + +GK + GF+ NRI Y E
Sbjct: 421 HFFAPVPVMTLVEVVPLPETSSHTLTVATQLVRDMGKVAVRAGPCNGFLGNRIYAAYRRE 480
Query: 637 ALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+ E G A D+D L+ GF MGPF + D
Sbjct: 481 CELLVEEG-AMPWDVDAELR-KQGFRMGPFQVGD 512
>UniRef50_Q8PMV7 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7;
Xanthomonadaceae|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Xanthomonas axonopodis pv. citri
Length = 693
Score = 106 bits (255), Expect = 5e-22
Identities = 71/221 (32%), Positives = 105/221 (47%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IA A G +VT+ D E ++ A G + K KDD + R++
Sbjct: 332 IAAWAAYKGFDVTLQDREQRFIDTAL----TRGGELFAKRVKDDAKR-----PAVAARLR 382
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
ADL+IEAI+E K+DL+ ++ +L TNTSSI + + I+R
Sbjct: 383 GDLAGAGVTQADLVIEAIIENPQAKRDLYQSIEPQLKPDALLTTNTSSIPLTDLRGHIQR 442
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRI 615
+F GLH+FNPV +M L+E+++ D + + + K++ K + TPGF+VNR+
Sbjct: 443 PAQFAGLHYFNPVAMMPLVEIVQHDGLDPANVARLAAFCKTLDKFPVPVAGTPGFLVNRV 502
Query: 616 LXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
L PY EA Y G +K G PMGP L D
Sbjct: 503 LFPYLLEAATAYAEGIPGPVLDKTAVKF--GMPMGPIELID 541
>UniRef50_Q11ME9 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=36; Bacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Mesorhizobium sp. (strain
BNC1)
Length = 740
Score = 106 bits (255), Expect = 5e-22
Identities = 72/222 (32%), Positives = 109/222 (49%), Gaps = 1/222 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IA VTA+AG V ++D + E +K + + + KK G+ KE L +
Sbjct: 342 IAYVTAKAGIPVVLIDRDQESADKGKAHSAGLMDGLIKK------GRATAEEKEKLLSLI 395
Query: 256 ISTKVEDSVN-ADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
+T ++ ADL+IEA+ E +K++ K + I A+NTS+I + ++ K
Sbjct: 396 TATPDYSALEGADLVIEAVFEDSAVKKEATEKAEAALKSSAIFASNTSTIPITSLAKNSK 455
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
R F GLHFF+PV M L+E+I + M++ +++ KT I DT GF VNR
Sbjct: 456 RPKNFIGLHFFSPVDRMMLVEIILGKKTGDKALALAMDYVRAIRKTPIVVNDTRGFYVNR 515
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+ Y EA M G I+ K+ AG P+GP L D
Sbjct: 516 CVLRYMQEAYSMLIEG-VPAPMIENAAKM-AGMPVGPLALTD 555
>UniRef50_Q28UL9 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=3; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase NAD-binding - Jannaschia
sp. (strain CCS1)
Length = 687
Score = 105 bits (253), Expect = 9e-22
Identities = 66/221 (29%), Positives = 107/221 (48%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IA G V +++ + + + +AQ +I +G K+ DD G DR+
Sbjct: 297 IAYACLSVGLPVVLLETDADAIARAQHNIDTLIGAGLKRGRLDDSG-----AAALRDRLT 351
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
++ + +A L+IEA E +D+K+D+F KLD T+LATNTS + V+ + + +
Sbjct: 352 LTEDYAAASDATLVIEAAFESMDVKKDIFAKLDAAVSPDTVLATNTSYLDVDVLAASTRD 411
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRI 615
+ GLHFF P +MRLLE++ S+ K + K + GF+ NRI
Sbjct: 412 PSRILGLHFFAPAHIMRLLEIVTGAETSDRALATGYALAKLLKKVPVLAGVCDGFIGNRI 471
Query: 616 LXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
Y EA + G A ++D ++ G+ MGPF + D
Sbjct: 472 FSRYKEEADILLMDG-AVPWEVDDAME-AFGYAMGPFEVGD 510
>UniRef50_Q08426 Cluster: Peroxisomal bifunctional enzyme (PBE)
(PBFE) [Includes: Enoyl-CoA
hydratase/3,2-trans-enoyl-CoA isomerase (EC 5.3.3.8) (EC
4.2.1.17); 3- hydroxyacyl-CoA dehydrogenase (EC
1.1.1.35)]; n=28; Euteleostomi|Rep: Peroxisomal
bifunctional enzyme (PBE) (PBFE) [Includes: Enoyl-CoA
hydratase/3,2-trans-enoyl-CoA isomerase (EC 5.3.3.8) (EC
4.2.1.17); 3- hydroxyacyl-CoA dehydrogenase (EC
1.1.1.35)] - Homo sapiens (Human)
Length = 723
Score = 105 bits (253), Expect = 9e-22
Identities = 58/162 (35%), Positives = 92/162 (56%)
Frame = +1
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
++++ V++ DL+IEA+ E++ +K+ +F +L + L TNTS++ V+ I S
Sbjct: 364 RLTSSVKELGGVDLVIEAVFEEMSLKKQVFAELSAVCKPEAFLCTNTSALDVDEIASSTD 423
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
R G HFF+P VM+LLEVI S + S T +M K + K + + GFV NR
Sbjct: 424 RPHLVIGTHFFSPAHVMKLLEVIPSQYSSPTTIATVMNLSKKIKKIGVVVGNCFGFVGNR 483
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+L PY +A + E G + E++D L+ GF MGPF ++D
Sbjct: 484 MLNPYYNQAYFLLEEG-SKPEEVDQVLE-EFGFKMGPFRVSD 523
>UniRef50_A6UH30 Cluster: 3-hydroxybutyryl-CoA epimerase; n=2;
Sinorhizobium|Rep: 3-hydroxybutyryl-CoA epimerase -
Sinorhizobium medicae WSM419
Length = 442
Score = 105 bits (251), Expect = 2e-21
Identities = 59/172 (34%), Positives = 89/172 (51%)
Frame = +1
Query: 223 GFVKESLDRIKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSI 402
G E L R+ +T ADLIIEA+ E LD+K+D+F K+ +LATNTS +
Sbjct: 103 GLAAERLARVTGATDYAVLAEADLIIEAVFEDLDVKRDVFRKVAAACRHDAVLATNTSYL 162
Query: 403 SVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITC 582
+ I GI ++F GLHFF+P VM+LLE++ + + + + + K +
Sbjct: 163 NPERIADGIASPERFLGLHFFSPAQVMKLLEIVPTGATAPEALATGFALARMLNKIPVRA 222
Query: 583 KDTPGFVVNRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+ GF+ NRIL +A R+ G A+ +D ++ G PMGPF D
Sbjct: 223 GISDGFIGNRILKVMRGQAERLLVTG-ASPSAVDAAMR-AFGLPMGPFEAQD 272
>UniRef50_A4WWF6 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=5; Rhodobacteraceae|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Rhodobacter sphaeroides ATCC 17025
Length = 673
Score = 105 bits (251), Expect = 2e-21
Identities = 69/221 (31%), Positives = 106/221 (47%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IA A AG T+ + P+ L K ++A + D G + L R+
Sbjct: 305 IAAAIAAAGLEATLAETGPDALEAGIKRVRAIFEAQVTRGLTDRAG-----AADRLARVS 359
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
+ + + DL+IEA+ E L +K+ +F L +L ILATNTS + I +G+
Sbjct: 360 GTVGLGPLADCDLVIEAVFEDLAVKRRVFEDLTRLCRPDAILATNTSYLDPERIVAGLPN 419
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRI 615
D+F LHFF+P VM+LLE++ + T +GK + + GF+ NRI
Sbjct: 420 PDRFIALHFFSPAQVMKLLEIVPLVATTSRTLATGFALAARLGKIPVQAGNGEGFIGNRI 479
Query: 616 LXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
L Y AEA + G A+ ++D ++ GF MGPF + D
Sbjct: 480 LKRYRAEAEALLFAG-ASPSEVDQAMR-AFGFGMGPFEMQD 518
>UniRef50_O17761 Cluster: Putative uncharacterized protein ech-8;
n=4; Caenorhabditis|Rep: Putative uncharacterized
protein ech-8 - Caenorhabditis elegans
Length = 437
Score = 105 bits (251), Expect = 2e-21
Identities = 67/203 (33%), Positives = 105/203 (51%), Gaps = 1/203 (0%)
Frame = +1
Query: 133 EILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIKISTKVEDSVNADLIIEAIV 312
E+ NKA + + L + K K + V++ ++I+T + N DLI+EA+
Sbjct: 69 EVNNKAAEFCKNEL-EITYKREKAFRRLNDSKVEKLRKNLQITTDFQKLNNCDLIVEAVF 127
Query: 313 EKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLL 492
E + +K++LF KLDK+ I TNTSS+ +N + S ++ K G+HFFNP ++R++
Sbjct: 128 EDMKLKKELFTKLDKICKPSCIFGTNTSSLDLNEMSSVLRDPTKVVGIHFFNPANLIRMV 187
Query: 493 EVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRILXPYSAEALR-MYERGDAT 669
EVI S E +S+ K + + P FV NR+L Y ++ + MYE G
Sbjct: 188 EVIYGSKTSSKAVATAFEACRSIKKLPVLVGNCPAFVFNRLLGVYLNQSQKLMYEYG-YL 246
Query: 670 KEDIDIGLKLGAGFPMGPFXLAD 738
ID + GF MGP +AD
Sbjct: 247 PHQID-KIITNFGFLMGPLTVAD 268
>UniRef50_Q5LVG3 Cluster: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase;
n=2; Rhodobacteraceae|Rep: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase -
Silicibacter pomeroyi
Length = 681
Score = 104 bits (250), Expect = 2e-21
Identities = 68/222 (30%), Positives = 109/222 (49%), Gaps = 1/222 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVK-ESLDRI 252
+A G +VT+++ + AQ+ + + K+ GKI + + L R+
Sbjct: 301 VAMACLGGGLSVTVIERDAAAAQAAQERVAGLVAAGVKR------GKISPDAQADMLARL 354
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
+ D+ +ADL IEA+ E LD+K+ +F L + ILATNTS + + +GI
Sbjct: 355 ATTDTYADASDADLAIEAVFEDLDVKRIVFADLAAVMRPDAILATNTSYLDPQLVFAGIA 414
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
+ GLHFF+P VM+LLE++K+ + + GK + K + GF+ NR
Sbjct: 415 NPARCLGLHFFSPAHVMKLLEIVKTPDTAPEVLATGFALGKRLRKISVLSGICDGFIGNR 474
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+L Y EA + G A ++D ++ G PMGPF L D
Sbjct: 475 MLAAYRREAEYLLADG-ALPHEVDAAMR-AQGLPMGPFELQD 514
>UniRef50_Q4Q939 Cluster: Trifunctional enzyme alpha subunit,
mitochondrial-like protein; n=6; Trypanosomatidae|Rep:
Trifunctional enzyme alpha subunit, mitochondrial-like
protein - Leishmania major
Length = 726
Score = 104 bits (250), Expect = 2e-21
Identities = 74/212 (34%), Positives = 110/212 (51%), Gaps = 2/212 (0%)
Frame = +1
Query: 109 VTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIKISTKVEDSVNA 288
V + DL E + + +++A R ++ + +++G K +L + T E +A
Sbjct: 333 VAVKDLTEESVKQGITNVRAEFERAVRRK-RMVTAELDG--KMAL--VTGGTTNEVFRDA 387
Query: 289 DLIIEAIVEKLDIKQDLFNKLDKLAPEHT--ILATNTSSISVNAIGSGIKRKDKFGGLHF 462
D+I+EA VE +DIK+ + +L+K H+ + ATNTSS+S+ + + K G+HF
Sbjct: 388 DVIVEAAVEVMDIKKKVIQQLEKDGILHSKSLFATNTSSLSLTEMQTVAKCPHNIVGMHF 447
Query: 463 FNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRILXPYSAEAL 642
FNPV M L+EVIK S + A+ GK I D PGF+VNRIL Y AEA
Sbjct: 448 FNPVSKMPLVEVIKGKSTSTEAAAAIFNLALKTGKIPIIVNDGPGFLVNRILGVYMAEAG 507
Query: 643 RMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
R+ +D + L G PMGPF L D
Sbjct: 508 RLAVDERCHPACVDEAI-LAFGMPMGPFRLLD 538
>UniRef50_A7INS1 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=5; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase NAD-binding -
Xanthobacter sp. (strain Py2)
Length = 789
Score = 104 bits (249), Expect = 3e-21
Identities = 75/230 (32%), Positives = 121/230 (52%), Gaps = 9/230 (3%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IA A AG V ++D+ PE A ++ A + +KL K DP F+ + ++
Sbjct: 33 IAAHVANAGIEVLLLDIVPE--GAANRNAIAE--KAVEKLLKADPA---AFMSKRAAKLV 85
Query: 256 ISTKVEDSVN----ADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGS 423
+ +ED+++ D I+EA++E+LDIKQ L+ K++ + +++NTS+I + + +
Sbjct: 86 TAGNIEDNLSDLASCDWIVEAVIERLDIKQALYAKIEAARRPGSAVSSNTSTIPLGDLTA 145
Query: 424 GIK---RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK-SVGKTCITCKDT 591
G+ R+D F HFFNP MRLLE++ + T A+ + +GKT +TCKDT
Sbjct: 146 GLPESFRRD-FLITHFFNPPRYMRLLEIVAGPETNPATVAAVARFADVKLGKTVVTCKDT 204
Query: 592 PGFVVNRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFP-MGPFXLAD 738
PGF+ NR+ + A+ R E+ D + GFP G F L D
Sbjct: 205 PGFIANRLGTYWLQLAVGEAFRLGLKVEEADAVMGRPFGFPKTGVFGLID 254
>UniRef50_Q73Q34 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putative;
n=1; Treponema denticola|Rep: 3-hydroxyacyl-CoA
dehydrogenase, putative - Treponema denticola
Length = 309
Score = 103 bits (246), Expect = 6e-21
Identities = 72/226 (31%), Positives = 118/226 (52%), Gaps = 5/226 (2%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGR-VAKKLYKDDPGKIEGFVKESLDRI 252
I++V A+AG V I+ L L A I+ +L VA+ L + + RI
Sbjct: 22 ISEVFAKAGHTVQIIGLNDASLKSALDRIKLSLNEFVAEGLVSASD------IDTIVGRI 75
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
ST ++ + +A ++IEA+ E +D+K + F KL+K+ P+ TILAT S SV+ + + +K
Sbjct: 76 SFSTDIQKAEDAAIVIEALPENMDLKTETFGKLEKICPQDTILAT-ASGHSVSEVIAQVK 134
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITC-KDTPGFVVN 609
++D+ HF+ P ++ L+EV + S+ T E K +GK + K+ GF+ N
Sbjct: 135 KRDRVIATHFWFPPQLLPLVEVCGAPETSKATIDTTCELLKGIGKKPVVIDKEIDGFIGN 194
Query: 610 RILXPYSAEALRMYERGDATKEDID--IGLKLGAGFPM-GPFXLAD 738
RI EA +Y+ G AT + ID + +G + + GP AD
Sbjct: 195 RIQFAALREAWALYDSGVATADAIDSIVRYSIGRRYSVTGPIESAD 240
>UniRef50_Q7D836 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=8; Mycobacterium tuberculosis complex|Rep:
3-hydroxyacyl-CoA dehydrogenase family protein -
Mycobacterium tuberculosis
Length = 304
Score = 102 bits (244), Expect = 1e-20
Identities = 78/246 (31%), Positives = 121/246 (49%), Gaps = 4/246 (1%)
Frame = +1
Query: 16 LLSHALKXXXXXXXXXXXXXIAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKL 195
L SH IA V A AG +V I D EIL+ A +++A RVA
Sbjct: 2 LTSHGFSRAAVVGAGLMGRRIAGVLASAGLDVAITDTNAEILHAA--AVEA--ARVA--- 54
Query: 196 YKDDPGKIEGFVKESLDRIKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHT 375
G G V + D ++ + D ADL+IEA+VE L +KQ+LF +L LAP+
Sbjct: 55 -----GAGRGSVAAAAD---LAAAIPD---ADLVIEAVVENLAVKQELFERLATLAPD-A 102
Query: 376 ILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK 555
+LATNTS + + A+ ++ + G HF+NP ++ ++EV+ S + DT ++
Sbjct: 103 VLATNTSVLPIGAVTERVEDGSRVIGTHFWNPPDLIPVVEVVPSARTAPDTADRVVALLT 162
Query: 556 SVGKTCITC-KDTPGFVVNRILXPYSAEALRMYERGDATKEDIDIGLKLGAGF---PMGP 723
VGK + +D PGF+ NR+ EA+ + G + +D+ ++ G +GP
Sbjct: 163 QVGKLPVRVGRDVPGFIGNRLQHALWREAIALVAEGVCDPKTVDLVVRNTIGLRLATLGP 222
Query: 724 FXLADY 741
ADY
Sbjct: 223 LENADY 228
>UniRef50_Q39CK1 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=44;
Proteobacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 710
Score = 101 bits (243), Expect = 1e-20
Identities = 58/166 (34%), Positives = 88/166 (53%)
Frame = +1
Query: 241 LDRIKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIG 420
L R K T + AD++IEA+ E + +K+ +F +L ++ +LATNTS + ++ +
Sbjct: 369 LARFKGGTSYDALAQADVVIEAVFEDMAVKKAVFAELARVCKPGAVLATNTSYLDIDELA 428
Query: 421 SGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGF 600
+ I R GLHFF+P VM+LLE++ +S D K + KT + GF
Sbjct: 429 ASIDRPADVIGLHFFSPANVMKLLEIVVPARVSADVVATAFALAKQLKKTPVRAGVCDGF 488
Query: 601 VVNRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+ NRIL Y A + E G A+ ID ++ GFPMGPF + D
Sbjct: 489 IGNRILAVYRTAADYLMEDG-ASPYQIDRAVR-EFGFPMGPFQVVD 532
>UniRef50_Q4REL3 Cluster: Chromosome 10 SCAF15123, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 10
SCAF15123, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 768
Score = 83.8 bits (198), Expect(2) = 1e-20
Identities = 38/97 (39%), Positives = 62/97 (63%)
Frame = +1
Query: 286 ADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFF 465
AD++IEA+ E + IK + +++ + P H ILATNTS++ + I + KR +K G+H+F
Sbjct: 392 ADMVIEAVFEDISIKHAVVKEVEAVVPPHCILATNTSALPIKDIAAASKRPEKVVGMHYF 451
Query: 466 NPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCI 576
+PV M+LLE+I ++ S+DT + + G GK I
Sbjct: 452 SPVDKMQLLEIITTEQTSKDTVASAVAVGLKQGKVII 488
Score = 38.7 bits (86), Expect(2) = 1e-20
Identities = 23/53 (43%), Positives = 28/53 (52%), Gaps = 1/53 (1%)
Frame = +1
Query: 583 KDTPGFVVNRILXPYSAEALRMYERG-DATKEDIDIGLKLGAGFPMGPFXLAD 738
+D PGF R L P AEA+R+ + G D K D L GFP+G LAD
Sbjct: 519 QDGPGFYTTRCLAPMLAEAVRLLQEGVDPKKLD---ALTTSFGFPVGAATLAD 568
>UniRef50_Q9RZ10 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putative;
n=11; Bacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase,
putative - Deinococcus radiodurans
Length = 347
Score = 101 bits (242), Expect = 2e-20
Identities = 62/223 (27%), Positives = 111/223 (49%), Gaps = 2/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IA TA G +V + D+ + KA++++ R + L D + F RI
Sbjct: 69 IAFQTAFHGFDVHLYDINDAAIAKARETLGKLQARYQQDLKVDAQQTGDAFA-----RIS 123
Query: 256 ISTKVEDSVNA-DLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
T + ++V DL+IEAI E +DIK+ +N+L ++A +TI ATN+S++ +
Sbjct: 124 FFTDIAEAVKGVDLVIEAIPENMDIKRKFYNQLGEVADPNTIFATNSSTLLPSQFMEETG 183
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITC-KDTPGFVVN 609
R +KF LHF N + E++++ + + ++++ K +G + K+ G+++N
Sbjct: 184 RPEKFLALHFANEIWKFNTAEIMRTPRTDDAVFDTVVQFAKDIGMVALPMYKEQAGYILN 243
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+L P AL + +G A + +D + G P GPF D
Sbjct: 244 TLLVPLLGAALELVVKGIADPQTVDKTWMIATGAPRGPFAFLD 286
>UniRef50_Q0EXX8 Cluster: Fatty oxidation complex, alpha subunit;
n=1; Mariprofundus ferrooxydans PV-1|Rep: Fatty
oxidation complex, alpha subunit - Mariprofundus
ferrooxydans PV-1
Length = 701
Score = 100 bits (240), Expect = 3e-20
Identities = 55/152 (36%), Positives = 85/152 (55%)
Frame = +1
Query: 283 NADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHF 462
+ D++IEA++E + +K+ L+ L K + T+L +NTSS+S++ + + GLHF
Sbjct: 381 DVDVVIEAVLEDIRVKRRLWASLGKHVRKDTLLLSNTSSLSISDMQHRRANAGRIAGLHF 440
Query: 463 FNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRILXPYSAEAL 642
FNP P M L+EV+ + + +T + S GK I ++PGF+VNR L PY AL
Sbjct: 441 FNPAPKMPLVEVVAGEKTTPETVDKVCALAVSWGKYPIIVAESPGFLVNRCLMPYMVAAL 500
Query: 643 RMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
++ G+ +D LK G PMG LAD
Sbjct: 501 KLVASGEKIGH-VDGALKC-FGMPMGALELAD 530
>UniRef50_Q3A7N5 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Pelobacter carbinolicus DSM 2380|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Pelobacter carbinolicus (strain DSM 2380
/ Gra Bd 1)
Length = 304
Score = 100 bits (239), Expect = 4e-20
Identities = 69/223 (30%), Positives = 107/223 (47%), Gaps = 2/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEG-FVKESLDRI 252
IA A G VTI D+ E+L QK I G A L + G I+ K +++RI
Sbjct: 21 IAFQCAAHGYFVTIYDISAEVLQATQKRI----GAYADYLVAE--GHIQPQAAKRAINRI 74
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
IST + NADL+ EA+ E +K ++F + D+ P+ TI +TN S + + I
Sbjct: 75 SISTDARQAANADLLCEAVPEDPALKGEVFARFDRYCPQRTIFSTNASLLVPSQIAKATG 134
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGK-TCITCKDTPGFVVN 609
R D+F LHF PV V L +V+ S + + + ++ KS+ + + K+ G+V N
Sbjct: 135 RPDRFLALHFHQPVWVGNLADVMPHAGTSSEVVKVVHDFAKSINQIPLVLNKENFGYVFN 194
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+ ++ A+ + G A DID P GP + D
Sbjct: 195 AMYSGLNSAAITLAANGVAAVPDIDRAWMTVMKMPKGPLGMLD 237
>UniRef50_A6FFH1 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenase;
n=1; Moritella sp. PE36|Rep: Probable 3-hydroxyacyl-CoA
dehydrogenase - Moritella sp. PE36
Length = 698
Score = 100 bits (239), Expect = 4e-20
Identities = 51/166 (30%), Positives = 86/166 (51%)
Frame = +1
Query: 241 LDRIKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIG 420
L RI S + D + D++IEA+ E +K ++ + I+A+NTS++ ++++
Sbjct: 374 LQRITPSKESADLIGCDMVIEAVFEDRKVKNQAITEILTAVGDELIMASNTSTLPISSLA 433
Query: 421 SGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGF 600
+ + + F GLHFF+PV M L+E+IK D S T A + +GK I D+ GF
Sbjct: 434 TASTKPENFIGLHFFSPVDKMPLVEIIKGDKTSSATLAAAYDLVIQIGKVPIVVNDSRGF 493
Query: 601 VVNRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+R+ Y +E +RM G ++ + AG P+GP + D
Sbjct: 494 FTSRVFFTYVSEGMRMLSEG--IPAEVIENAAIQAGLPVGPLAITD 537
Score = 35.5 bits (78), Expect = 1.4
Identities = 20/39 (51%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Frame = +1
Query: 601 VVNRILXPYSAEALRMYERGDATK-EDIDIGLKLGAGFP 714
V +R+L S EALR YE G T D +IG LG GFP
Sbjct: 618 VKDRLLFVQSLEALRAYEEGVVTSTRDANIGSILGLGFP 656
>UniRef50_Q6N3H7 Cluster: Enoyl-CoA hydratase; n=26; Bacteria|Rep:
Enoyl-CoA hydratase - Rhodopseudomonas palustris
Length = 699
Score = 99 bits (238), Expect = 6e-20
Identities = 67/223 (30%), Positives = 110/223 (49%), Gaps = 2/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKK--LYKDDPGKIEGFVKESLDR 249
IA A AG VT+++ E L + +Q N A + L D P K + +
Sbjct: 310 IAMSFANAGIPVTLIETGEEQLKRGLGIMQKNWEATAARGGLPPDAPAKRMALITGLVG- 368
Query: 250 IKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGI 429
+E+ +ADLIIEA+ E + +K+++F +D A +LA+NTS +S++ I +
Sbjct: 369 ------LENVKDADLIIEAVFETMAVKKEVFTAVDAHAKPGAVLASNTSYLSIDEIAATT 422
Query: 430 KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVN 609
KR G+HFF+P VM+L E+++ + D + K + K + GFV N
Sbjct: 423 KRPQDVLGMHFFSPANVMKLCEIVRGAKTAPDALLTAVSIAKKIAKVPVVVGVCDGFVGN 482
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
R+L S ++ ++ G A + +D + G PMGPF + D
Sbjct: 483 RMLAARSKQSEKLLFEG-ALPQQVD-AVVTKFGMPMGPFAMGD 523
>UniRef50_Q0RL76 Cluster: Putative 3-hydroxybutyryl-CoA
dehydrogenase; n=1; Frankia alni ACN14a|Rep: Putative
3-hydroxybutyryl-CoA dehydrogenase - Frankia alni
(strain ACN14a)
Length = 234
Score = 99 bits (238), Expect = 6e-20
Identities = 63/222 (28%), Positives = 105/222 (47%), Gaps = 3/222 (1%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IAQ A AG V VD +A++ + GR + + V RI
Sbjct: 6 IAQAVAVAGGAVVCVDTSAAARERARRQLVE--GRFGLRAAVERGKLAAADVDRVAARIS 63
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
+++ A ++IEA+ E L +K +F +LD++A +LATN+S V A+ + R
Sbjct: 64 WESELSAVAGAAVVIEAVPEDLALKVRVFRELDRVAAAGAVLATNSSGFPVGALAAATDR 123
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTP---GFVV 606
+ G H+ +P +MR E++ ++H D + +GK + +D P G+V
Sbjct: 124 PTRVLGWHWSSPAQIMRFAEIVVTEHTDPDAVATVTRLAHGLGKNPVVVRDAPMAWGYVA 183
Query: 607 NRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXL 732
NR+ AEA R+ G +T+ D+D L +P+GPF +
Sbjct: 184 NRVYWAAVAEARRIVAEGVSTERDVDQLLVDCFRWPVGPFTM 225
>UniRef50_A3QGY2 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=3; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Shewanella loihica (strain
BAA-1088 / PV-4)
Length = 708
Score = 99 bits (238), Expect = 6e-20
Identities = 64/213 (30%), Positives = 108/213 (50%), Gaps = 2/213 (0%)
Frame = +1
Query: 106 NVTIVDLEPEILNKAQKSIQANLGRVAKKL-YKDDPGKI-EGFVKESLDRIKISTKVEDS 279
N V + +IL+ ++++ LG + K Y GK+ + + E + + +T D
Sbjct: 317 NFINVGIPTQILDLNGEALERGLGVIRKNYEYTLKKGKLSQAQLDERMALLSGTTDYADI 376
Query: 280 VNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKRKDKFGGLH 459
+ DL+IEA+ EK++IK+ +F LD ILATNTS++ V+ I + R GLH
Sbjct: 377 ADVDLVIEAVFEKMEIKKQVFKTLDATCKPGAILATNTSTLDVDEIAAETSRPQDVLGLH 436
Query: 460 FFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRILXPYSAEA 639
FF+P VMRLLE+++++ + D ++ + + K + GF+ NR Y E+
Sbjct: 437 FFSPANVMRLLEIVRANKTAPDALLTTVQLAQRIKKVPVVSGVCWGFIGNRATDSYLRES 496
Query: 640 LRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+ + G A+ ID + G PMG + D
Sbjct: 497 MSLILEG-ASPAQID-KVHTEFGMPMGLPSMVD 527
Score = 32.7 bits (71), Expect = 9.7
Identities = 20/50 (40%), Positives = 26/50 (52%), Gaps = 4/50 (8%)
Frame = +1
Query: 601 VVNRILXPYSAEALRMYERGDATK-EDIDIGLKLGAGFPM---GPFXLAD 738
++ R + P E R+ E G A + DIDI L G GFP+ GP AD
Sbjct: 613 ILERTIYPIINEGARILEEGIALRASDIDIVLAYGFGFPIFRGGPMQYAD 662
>UniRef50_A5ULU2 Cluster: 3-hydroxyacyl-CoA dehydrogenase, FadB;
n=3; cellular organisms|Rep: 3-hydroxyacyl-CoA
dehydrogenase, FadB - Methanobrevibacter smithii (strain
PS / ATCC 35061 / DSM 861)
Length = 318
Score = 99.5 bits (237), Expect = 7e-20
Identities = 59/185 (31%), Positives = 100/185 (54%), Gaps = 2/185 (1%)
Frame = +1
Query: 190 KLYKDDPGKIEGFVKESLDRIKISTKVEDSVN-ADLIIEAIVEKLDIKQDLFNKLDKLAP 366
+L D +++ V+++ D I ++T E++ N ADLIIEAI E K + +L K P
Sbjct: 83 ELSADKINELKQKVEDAYDSITLTTSYEEAGNDADLIIEAIAEDPKQKIAFYQELAKHIP 142
Query: 367 EHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMME 546
E TI+ATN+S++ +A R +K+ LHF N + E++ ++ Y A+ E
Sbjct: 143 EKTIIATNSSTMLPSAFAQYTGRPEKYLALHFANEIWRNNTAEIMGHPDTGQEYYDAVCE 202
Query: 547 WGKSVGKTCITC-KDTPGFVVNRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGP 723
+ +++ + K+ PG+++N +L P+ + A +Y G A E ID L G P+GP
Sbjct: 203 FAENINMIPLKLKKEQPGYILNSMLVPFLSAAEALYADGVADFETIDKTWMLATGAPLGP 262
Query: 724 FXLAD 738
F + D
Sbjct: 263 FRILD 267
>UniRef50_Q7WIS8 Cluster: Putative enoyl-CoA isomerase; n=2;
Bordetella|Rep: Putative enoyl-CoA isomerase -
Bordetella bronchiseptica (Alcaligenes bronchisepticus)
Length = 694
Score = 99.1 bits (236), Expect = 1e-19
Identities = 55/151 (36%), Positives = 80/151 (52%)
Frame = +1
Query: 286 ADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFF 465
ADL IEA+ E + +K +F +LD++ IL TNTS++ V+ I +R GLHFF
Sbjct: 367 ADLAIEAVFEDMAVKCAVFRELDRVLKPGAILGTNTSTLDVDRIAHSTRRPQDVVGLHFF 426
Query: 466 NPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRILXPYSAEALR 645
+P PVM LLE+++ D A + + KT + GF+ NR+ Y +A
Sbjct: 427 SPAPVMPLLEIVRGAATHADVVAAAQGLARRLRKTAVVAGVCDGFIGNRMWHQYLRQAAL 486
Query: 646 MYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
M G A ++D L+ GF MGPF +AD
Sbjct: 487 MVHEG-AMPMEVDAALR-DWGFAMGPFQVAD 515
>UniRef50_Q2S396 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
C-terminal domain family; n=1; Salinibacter ruber DSM
13855|Rep: 3-hydroxyacyl-CoA dehydrogenase, C-terminal
domain family - Salinibacter ruber (strain DSM 13855)
Length = 802
Score = 99.1 bits (236), Expect = 1e-19
Identities = 53/159 (33%), Positives = 93/159 (58%), Gaps = 6/159 (3%)
Frame = +1
Query: 226 FVKESLDRIKISTKVE--DSVNA-DLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTS 396
F E+ DR+ + E D + A D I+EA+VE++D+K+D+ +++ A + +++TNTS
Sbjct: 80 FADEAADRVHLGNFEEHFDRIGAVDWIVEAVVERMDVKRDVHARIEAHAADDAVISTNTS 139
Query: 397 SISVNAI--GSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK-SVGK 567
+ ++AI G K +F G HF+NP ++LLE++ +D D + + ++G+ +GK
Sbjct: 140 GLPIHAITEGRSADFKRRFLGTHFYNPPRYLKLLELVPTDATDPDVTERVAQFGRLRLGK 199
Query: 568 TCITCKDTPGFVVNRILXPYSAEALRMYERGDATKEDID 684
+ D P F+ NRI +A+R + GD T E+ID
Sbjct: 200 GIVVANDVPYFIGNRIGVFAQLQAIRYFTDGDYTIEEID 238
>UniRef50_Q1DAC1 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=1; Myxococcus xanthus DK 1622|Rep: Putative
3-hydroxyacyl-CoA dehydrogenase - Myxococcus xanthus
(strain DK 1622)
Length = 321
Score = 99.1 bits (236), Expect = 1e-19
Identities = 57/169 (33%), Positives = 96/169 (56%), Gaps = 2/169 (1%)
Frame = +1
Query: 238 SLDRIKISTKV-EDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNA 414
++ RI+ +T + E +V DL+IE+I E L +KQ LF +LD+LA T+LATNT+++SV A
Sbjct: 70 AIGRIRRTTVLAEAAVEQDLVIESIPEDLALKQQLFRELDQLAAPDTLLATNTTALSVTA 129
Query: 415 IGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKT-CITCKDT 591
I R ++ H++ P ++ L+++I + S D + + + + +GK+ + +D
Sbjct: 130 IARDCTRPERVLSAHYYLPAHLIPLVDIIPGEKTSPDAVETVRRFIEELGKSPVVFSRDV 189
Query: 592 PGFVVNRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
PG V R+ EA+R+ G AT E +D L G G +G + D
Sbjct: 190 PGSVGPRLQQALIGEAIRLVHEGVATPEMVDRVLTQGVGRRLGASGVFD 238
>UniRef50_A0JTB4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=5;
Actinomycetales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Arthrobacter sp. (strain FB24)
Length = 333
Score = 99.1 bits (236), Expect = 1e-19
Identities = 69/226 (30%), Positives = 113/226 (50%), Gaps = 5/226 (2%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGR-VAKKLYKDDPGKIEGFVKESLDRI 252
IAQV A G V + D+ E+ + A + VA L+ P +K++L
Sbjct: 34 IAQVLALGGARVALADVSAEVAQSNYDRLLAESDQFVADGLF---PAGSTEILKQNLWAA 90
Query: 253 KISTKVEDSV-NADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGI 429
+ +E++V +AD I EA+ E + IK ++ A I+ +NTS+IS+ + +
Sbjct: 91 R---DIEEAVADADFIEEAVPEIIAIKHQTLARISAAARPDAIIGSNTSTISIADLSEPV 147
Query: 430 KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVN 609
++F G+HF NP P + +E+I S T A+ + + GK KD GFV+N
Sbjct: 148 TNPERFLGVHFSNPSPFIPGVEIIPHAGTSATTVGAVRDLVHAAGKQTAVVKDVTGFVLN 207
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPM---GPFXLAD 738
R+ EA ++ E+G AT +D+D ++ GF + GPF +AD
Sbjct: 208 RLQYALFHEAAQLVEQGIATADDVDTLVRTTFGFRLPFFGPFAIAD 253
>UniRef50_Q28N18 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=23; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase NAD-binding - Jannaschia
sp. (strain CCS1)
Length = 733
Score = 98.7 bits (235), Expect = 1e-19
Identities = 66/222 (29%), Positives = 107/222 (48%), Gaps = 1/222 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKES-LDRI 252
IA V+A AG V ++D + ++ + + L + K+ GK+ K L +I
Sbjct: 342 IAYVSALAGIEVVLIDAAQDSADRGKAYSEGLLDKGMKR------GKVTEEKKAKVLGQI 395
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
+T + DLI+EA+ E +K ++ K + I ATNTS++ + +
Sbjct: 396 TATTDYDALNGCDLIVEAVFEDPKVKAEVTAKAEAAMNADGIFATNTSTLPITMLAKASS 455
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
R ++F G+HFF+PV M L+E+IK + +++ + + KT I D F NR
Sbjct: 456 RAEQFIGIHFFSPVDKMALVEIIKGKQTGDVAVAKALDFVRQIRKTPIVVNDERFFYANR 515
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+ PY E +RM + G A I+ KL G P+GP L D
Sbjct: 516 CILPYVNEGVRMLQEGVAPAL-IENAAKL-VGMPLGPLQLTD 555
>UniRef50_A5VHQ1 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=2; Lactobacillus reuteri|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Lactobacillus reuteri F275
Length = 294
Score = 98.7 bits (235), Expect = 1e-19
Identities = 61/222 (27%), Positives = 115/222 (51%), Gaps = 1/222 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IA TA +G NV++ + ++ A++ I+A + L+ D +G +
Sbjct: 16 IAYQTALSGFNVSVYNHH---IDTAERRIKALKSDYERDLHLTDKEFQQGLNNIKVITDD 72
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
++T V+D ADL+IEA+ E L++K+ + ++ +LAPE TI A+N+S+ + + R
Sbjct: 73 VATAVKD---ADLMIEALPESLELKEQFYEEVSELAPEKTIFASNSSTFIPSQLAPYTDR 129
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKT-CITCKDTPGFVVNR 612
+KF +HF N + ++E++ + S + + ++ + + I K+ G+++N
Sbjct: 130 PEKFLNMHFANQIWKFNVVEIMGTSQTSPEVIEEATKFAREIKMVPVILNKEQHGYILNS 189
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+L P A L ++ +G A ID + G PMGPF + D
Sbjct: 190 LLIPLLASGLSLWAKGVADPAMIDKDWMISTGAPMGPFGILD 231
>UniRef50_A0J682 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Shewanella woodyi ATCC 51908|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Shewanella woodyi ATCC 51908
Length = 696
Score = 98.7 bits (235), Expect = 1e-19
Identities = 53/168 (31%), Positives = 90/168 (53%)
Frame = +1
Query: 235 ESLDRIKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNA 414
+ + +K ST + DL++EA E L++K+ +F LD+ + ILATNTS + +N+
Sbjct: 368 DKMQLVKGSTVYDRLAPCDLVVEAAFEDLEVKKIIFKALDQHCKDSAILATNTSYLDINS 427
Query: 415 IGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTP 594
I R D+ GLHFF+P VM+L+E++++++ ++D + M+ G + K +
Sbjct: 428 IAKVTSRPDQVVGLHFFSPAHVMKLIEIVRAENTADDVIKTMLALGVKLRKYPVEVGVCF 487
Query: 595 GFVVNRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
GF NR+ Y E +M G++ ID + G MGP + D
Sbjct: 488 GFAANRMYTRYGREIQQMLLEGNSIVA-IDEAM-TSFGMAMGPLTVQD 533
>UniRef50_Q988C8 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1;
Mesorhizobium loti|Rep: 3-hydroxybutyryl-coA
dehydrogenase - Rhizobium loti (Mesorhizobium loti)
Length = 309
Score = 97.9 bits (233), Expect = 2e-19
Identities = 53/168 (31%), Positives = 94/168 (55%), Gaps = 5/168 (2%)
Frame = +1
Query: 250 IKISTKVEDSVN-ADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSG 426
++ + + D+V+ ADL+IE + E + IK D++ +D L + TI+A++TS I + + +
Sbjct: 67 VRFTDDIGDAVSGADLVIENVPENISIKADVYRTIDGLIGQDTIVASDTSGIPITKLQAH 126
Query: 427 IKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVG-KTCITCKDTPGFV 603
I ++ G+H+ NP ++ ++EVI + + T + + +S+G + KD PGFV
Sbjct: 127 ISYPERMVGMHWSNPPHIIPMIEVIAGEKTAPQTVATIRDLIRSIGLLPVVVKKDVPGFV 186
Query: 604 VNRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFP---MGPFXLAD 738
NR+L EA+ + ERG ED+D + G G+ +GP L D
Sbjct: 187 ENRVLYALLREAVDLVERGVIDPEDLDTCVSWGIGYKIAVIGPMALLD 234
>UniRef50_Q5KVJ3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=16;
Bacillaceae|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Geobacillus kaustophilus
Length = 795
Score = 97.9 bits (233), Expect = 2e-19
Identities = 65/196 (33%), Positives = 103/196 (52%), Gaps = 16/196 (8%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQ---------KSIQANLGRVA-KKLYKDDPGKIEG 225
IA A G ++D+ P L K + K ++ L A ++L K P +
Sbjct: 20 IAAHLANVGIPTLLLDIVPRELTKEEEAKGWTLEHKQVRNRLANQALERLLKQKPAPLMS 79
Query: 226 FVKESLDRIKISTKVEDS---VNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTS 396
K+++ I+ +D D IIEA+VEKL++K+++F ++D++ TI+++NTS
Sbjct: 80 --KDNIALIETGNFEDDFHRLAEVDWIIEAVVEKLEVKKEVFARVDEVRTPGTIVSSNTS 137
Query: 397 SISVNAIGSGIKR--KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSV-GK 567
IS+ A+ G K F G HFFNP ++LLE+I ++H D M +G+ V GK
Sbjct: 138 GISIAAMAEGRSDDFKKHFLGTHFFNPPRYLKLLEIIPTEHTDPDVVAYMKSFGEDVLGK 197
Query: 568 TCITCKDTPGFVVNRI 615
+ KDTP F+ NRI
Sbjct: 198 GVVMAKDTPNFIANRI 213
>UniRef50_A1SQH4 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=104; cellular organisms|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Nocardioides sp. (strain BAA-499 / JS614)
Length = 736
Score = 97.9 bits (233), Expect = 2e-19
Identities = 64/221 (28%), Positives = 102/221 (46%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IA A++G V + D+ E K + + L + K + K E L RI
Sbjct: 339 IAYSCARSGMEVVLKDVAVESAEKGKAYSEKLLDKAIAKGRSTEEKKAE-----LLGRIT 393
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
+ D DL+IEA+ E +KQ +F ++ + +L +NTS++ + + SG+ R
Sbjct: 394 ATADAADLAGCDLVIEAVFEDPSLKQQVFAEIAPYVDQDALLCSNTSTLPITELASGVDR 453
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRI 615
F GLHFF+PV M L+E+I+ S+ + + + KT I D+ GF +R+
Sbjct: 454 PADFIGLHFFSPVDKMPLVEIIRGAKTSDVALAKAYDVVQQIRKTPIVVNDSRGFYTSRV 513
Query: 616 LXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+ E L M G G + AG+P+GP L D
Sbjct: 514 IGTQVMEGLAMVAEGLHPVSIERAGTQ--AGYPVGPLQLTD 552
>UniRef50_A6GBG1 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerase family protein; n=1; Plesiocystis
pacifica SIR-1|Rep: 3-hydroxyacyl-CoA
dehydrogenase/enoyl-CoA hydratase/isomerase family
protein - Plesiocystis pacifica SIR-1
Length = 789
Score = 97.5 bits (232), Expect = 3e-19
Identities = 79/231 (34%), Positives = 112/231 (48%), Gaps = 10/231 (4%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNK-AQKSIQANLGRVA-KKLYKDDPGKIEGFVKESLDR 249
IA A AG ++D+ P ++ A K+ + L A K L K P + K R
Sbjct: 5 IAAHLANAGIRTYLLDIVPRGVDADAPKAARNKLAAGALKALPKAKPPALMN--KAFAGR 62
Query: 250 IKISTKVEDSVNA----DLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAI 417
I +D A D++IEAI+E+LDIKQ +F K+ A E TILA+NTS I + I
Sbjct: 63 ITAGNFDDDLERAVAESDIVIEAIIERLDIKQTVFKKVAAAAKETTILASNTSGIPIADI 122
Query: 418 GSGIKR--KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSV-GKTCITCKD 588
+ +++F GLHFFNP M LLEVI S + ++ + ++ V GK + C+D
Sbjct: 123 AEALDEGARERFLGLHFFNPPRWMHLLEVIPSKYTAKKYVDEVAKFSDEVLGKGVVLCRD 182
Query: 589 TPGFVVNRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFP-MGPFXLAD 738
TP F+ NRI G T E++D G P G + L D
Sbjct: 183 TPNFIGNRIGIGEMLLTFAATLEGKYTIEEVDTLNGKPVGRPKTGSYRLGD 233
>UniRef50_Q5LKF7 Cluster: Fatty oxidation complex, alpha subunit;
n=5; Bacteria|Rep: Fatty oxidation complex, alpha
subunit - Silicibacter pomeroyi
Length = 714
Score = 97.1 bits (231), Expect = 4e-19
Identities = 70/223 (31%), Positives = 110/223 (49%), Gaps = 2/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKES-LDRI 252
IA A AG V + D + L A++ +A + K K G++ +E+ L I
Sbjct: 332 IAFSAATAGLPVVLKD---QTLEAAERG-KAYTATLLDKRVKQ--GRMSAEEREAVLALI 385
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
+ K +D DLIIEA+ EK+DIK + + + L E+ I +NTS++ + + +G
Sbjct: 386 TPTDKADDLKGCDLIIEAVFEKIDIKDAVLAEHEALLAENGIWGSNTSTLPITRLATGAT 445
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
R + F GLHFF+PV M LLE+I + S++T ++ + + KT I D+ GF +R
Sbjct: 446 RPENFVGLHFFSPVDKMPLLEIIAGEKTSDETLARAFDFARQIRKTPIIVGDSTGFYTSR 505
Query: 613 ILXPYSAEALRMYERG-DATKEDIDIGLKLGAGFPMGPFXLAD 738
+ EA+ + G D + D L G P G L D
Sbjct: 506 TIGTKIIEAVELVAEGHDPLRVD---NLSRLTGMPTGMLSLLD 545
>UniRef50_Q2SGN8 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Hahella chejuensis KCTC 2396|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Hahella chejuensis (strain KCTC 2396)
Length = 283
Score = 97.1 bits (231), Expect = 4e-19
Identities = 56/169 (33%), Positives = 86/169 (50%)
Frame = +1
Query: 232 KESLDRIKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVN 411
++ LD I+ S ++ + ++E I E +++KQ L+ ++ + + +LA NTS I +
Sbjct: 66 QDILDNIRWSNELGAISDCAFVVENIPENIELKQALYTRMAEFIAPNAVLAANTSCIPIT 125
Query: 412 AIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDT 591
+GS K + G+HF NPV + +EVI + SE T +E +GK + KD
Sbjct: 126 KLGSFHKTSAQVIGVHFMNPVYLKHTVEVILGLNTSEQTKDRCLEMLAMLGKKAVVVKDG 185
Query: 592 PGFVVNRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
PGFV NRI + EA + G A D+D K G MGP AD
Sbjct: 186 PGFVSNRISHLFMNEAAFAIQDGIAQPADVDAIFKECFGHKMGPLETAD 234
>UniRef50_Q0YNJ7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Geobacter sp. FRC-32|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Geobacter sp. FRC-32
Length = 311
Score = 97.1 bits (231), Expect = 4e-19
Identities = 62/221 (28%), Positives = 101/221 (45%), Gaps = 4/221 (1%)
Frame = +1
Query: 91 AQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIKISTK- 267
A +G V D P+ L + AKK DDP FV ++ +I++ +
Sbjct: 20 AMSGHEVHCHDASPQTLAGTVAGCEKLAATAAKKFKHDDPN----FVSNAMGKIRVHNEK 75
Query: 268 ---VEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKRK 438
++ + D+ +E I E L +K + P + +N+SS+ ++ + R
Sbjct: 76 GAFIDAAKGCDVFLEVIFEDLKLKCSVLADYLPQLPPSVVFWSNSSSLDIDPMAQAGGRP 135
Query: 439 DKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRIL 618
D+ H NPVP+M +EV+ S +T + + ++ K + PGF VNR+L
Sbjct: 136 DRSIVTHGMNPVPLMPGVEVVPGAKTSSETIEFTRQTLLNMKKAPFLAPNIPGFWVNRLL 195
Query: 619 XPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLADY 741
P +A+R+ E+G T ED D GL G P G F L D+
Sbjct: 196 VPQMLDAVRLLEQGKITVEDGDTGLYTSLGHPQGTFKLHDF 236
>UniRef50_Q4FL01 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Pelagibacter ubique
Length = 740
Score = 95.5 bits (227), Expect = 1e-18
Identities = 63/186 (33%), Positives = 103/186 (55%), Gaps = 6/186 (3%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IA A VT++DL+ EI +A+ K+YK P + K + IK
Sbjct: 18 IAAHLCNANIPVTLLDLKTEISEQARD-----------KIYKSRPPLL--LDKSKIKNIK 64
Query: 256 ISTKVE--DSVN-ADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSG 426
+ ++ D V AD ++EA+VE++DIK D++ K+ K + I+++NTSSI + +
Sbjct: 65 VGNILDNFDEVKEADWVVEAVVERIDIKHDIYKKIFKERKKGAIVSSNTSSIPIKILSQH 124
Query: 427 IKRKDK--FGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKS-VGKTCITCKDTPG 597
+ ++K F HFFNPV M LLE++K+++ D ++ + ++ +GK I C DTPG
Sbjct: 125 LSEEEKKDFCITHFFNPVRYMGLLEIVKNENNDLDKINSLKAFCETELGKGAIICNDTPG 184
Query: 598 FVVNRI 615
F+ NRI
Sbjct: 185 FLGNRI 190
>UniRef50_Q89HA7 Cluster: Blr6087 protein; n=6; Proteobacteria|Rep:
Blr6087 protein - Bradyrhizobium japonicum
Length = 330
Score = 95.1 bits (226), Expect = 2e-18
Identities = 66/230 (28%), Positives = 112/230 (48%), Gaps = 8/230 (3%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYK-DDPGKI-EGFVKESLDR 249
IA A AG VT++D++P K LG V K + G + E V + R
Sbjct: 19 IAVAFAYAGHRVTMIDVKPRSAEDFAKLETDALGEVRKTFASLSNLGLLTEADVDPLVAR 78
Query: 250 IKISTKVEDSV---NADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIG 420
+ ++T + +A ++ E + E +++K+++ + TI+A+ TS+I V+ +
Sbjct: 79 VSVATASQSGTALADAGMVFEGVPEVVELKREVLGAASRQVKPDTIIASTTSTILVDDLS 138
Query: 421 SGIKRKDKFGGLHFFNPVPVMRLLEVIK---SDHISEDTYQAMMEWGKSVGKTCITCKDT 591
I +F +H+ NP ++ L+EV +D D +A++E +GK + C T
Sbjct: 139 GAIVNPHRFLNVHWLNPAYLIPLVEVSPGKATDPAIIDEVKALLE---GIGKVPVVCAAT 195
Query: 592 PGFVVNRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLADY 741
PGF+V RI EA RM E G A+ E+ID ++ G GF L ++
Sbjct: 196 PGFIVPRIQALAMNEAARMVEEGVASAEEIDKAIRYGFGFRYAVLGLLEF 245
>UniRef50_Q24N80 Cluster: Putative uncharacterized protein; n=1;
Desulfitobacterium hafniense Y51|Rep: Putative
uncharacterized protein - Desulfitobacterium hafniense
(strain Y51)
Length = 313
Score = 95.1 bits (226), Expect = 2e-18
Identities = 70/226 (30%), Positives = 115/226 (50%), Gaps = 5/226 (2%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IAQ+ A G V + D PE L++A++ I N+ + L K+ E + + I
Sbjct: 19 IAQLYACKGFQVALYDKFPEQLDRAKQLIANNM----ENLIKEGLATQEE-AERTKTLIS 73
Query: 256 ISTKVEDSV-NADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
T++E ADL++E++ E D+K++ F +LDKL IL +NTS+ ++ I + +
Sbjct: 74 YETELEKCAPQADLVLESVFENADVKRETFAQLDKLCASDCILCSNTSASNIFEI-APVS 132
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKD-TPGFVVN 609
++ H+FNP +M L+EV+ S++T + + VGK K PGF+VN
Sbjct: 133 HPERQIITHYFNPPFIMDLVEVVMGPKTSDETLDKVKSFLIQVGKEPAVLKQYIPGFIVN 192
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPM---GPFXLAD 738
RI + EA M +G + +DID ++ +G GP L D
Sbjct: 193 RIATAITREAGYMVTQGWVSAQDIDSAIRNTSGIRYAFEGPMALYD 238
>UniRef50_A5IPA0 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=14; Staphylococcus|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Staphylococcus aureus subsp. aureus JH9
Length = 753
Score = 95.1 bits (226), Expect = 2e-18
Identities = 58/162 (35%), Positives = 87/162 (53%), Gaps = 6/162 (3%)
Frame = +1
Query: 271 EDSVN--ADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKRKD- 441
+D VN ADL IEA+ E ++IK ++ ++ + A E + ATNTS I +NAI KD
Sbjct: 76 DDLVNDDADLYIEAVKEDIEIKHAVWQQVLQHAKEDALFATNTSGIPINAIAQAFNEKDQ 135
Query: 442 -KFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSV-GKTCITCKDTPGFVVNRI 615
+F GLHFFNP +M+L+E+I + H E + + ++V GK I D PGFV NR+
Sbjct: 136 ERFFGLHFFNPPRIMKLVELIPTSHTKESIILDVKNFAQNVLGKGVIVVNDVPGFVANRV 195
Query: 616 LXPYSAEALRMYERGDATKEDIDIGLKLGAGFP-MGPFXLAD 738
+ + E+ + D+D G P G + L+D
Sbjct: 196 GTQTMNDIMYRAEQHKLSIVDVDALTGQAIGRPKTGTYALSD 237
>UniRef50_Q1LBV6 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=4; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Ralstonia metallidurans
(strain CH34 / ATCC 43123 / DSM 2839)
Length = 714
Score = 94.7 bits (225), Expect = 2e-18
Identities = 61/221 (27%), Positives = 101/221 (45%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IA +A G + D+ + K + + L + K K P K + E L RI
Sbjct: 330 IAYASAMRGIEAVLKDVSLDHAGKGKLHSEKLLEKGVSK-GKISPSKRD----EVLQRIT 384
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
+ D+IIEA+ EK ++K ++ + + E+ + A+NTS++ + +
Sbjct: 385 PTADASGLAGCDIIIEAVYEKRELKAEVTREAEPHLAENGLFASNTSTLPITGLAEASAS 444
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRI 615
+ F GLHFF+PV M L+E+IK S T +++ K +GKT I D+ GF +R+
Sbjct: 445 PENFIGLHFFSPVDRMPLVEIIKGKKTSSRTLAHAIDFVKQIGKTPIVVNDSRGFFTSRV 504
Query: 616 LXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
++ E M G + L G P+GP + D
Sbjct: 505 FGTFTKEGAAMLSEG--VPAAVIENAALSVGMPVGPLAVMD 543
>UniRef50_A6GC68 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Plesiocystis pacifica SIR-1|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Plesiocystis pacifica SIR-1
Length = 733
Score = 94.7 bits (225), Expect = 2e-18
Identities = 57/195 (29%), Positives = 95/195 (48%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
+A + A AG V + D+ E L+K +A L + +K + DD G+ +++ L
Sbjct: 347 LAYICADAGYQVVLKDINQEALDKGVAHFEAQLRK--RKRHLDDAGRQA--IRDRLTPSL 402
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
+ + D+ DLIIEA+ E LD+K + + + I A+NTS+I + +
Sbjct: 403 ELSALSDNGGTDLIIEAVFENLDLKHRVTRETEPTLSADGIWASNTSAIPIGDLAKVSAH 462
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRI 615
D+F GLH+F+PV VM LLE++ SE T +++ + + K I D F +R+
Sbjct: 463 ADRFIGLHYFSPVEVMPLLEIVVGPETSERTLARCLDFCRRIKKLPIVVNDGYAFFTSRV 522
Query: 616 LXPYSAEALRMYERG 660
Y E + G
Sbjct: 523 FSSYIMEGASLVAEG 537
>UniRef50_A3U7V8 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerasefamily protein; n=19; Bacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerasefamily protein - Croceibacter
atlanticus HTCC2559
Length = 802
Score = 94.7 bits (225), Expect = 2e-18
Identities = 66/212 (31%), Positives = 102/212 (48%), Gaps = 14/212 (6%)
Frame = +1
Query: 91 AQAGQNVTIVDLEPEILNKAQKSIQANL-GRVAKKLYKDDP--GKIEG-----FVKESLD 246
A G V ++D+ P LN+ +K+ L +V + +D I+ + K+
Sbjct: 26 ANIGVEVLLLDIVPRELNEKEKAKGLTLEDKVVRNRIVNDALQSSIKSKPAPLYHKDFAS 85
Query: 247 RIKISTKVEDSV---NADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAI 417
RI +D + D IIE +VE+LDIK+ +F L+K E T++ +NTS I +N +
Sbjct: 86 RISTGNLEDDIAKVKDVDWIIEVVVERLDIKKQVFENLEKHRTEGTLITSNTSGIPINLM 145
Query: 418 GSGIKR--KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWG-KSVGKTCITCKD 588
G + F G HFFNP + L E+I S + + +G K +GKT I KD
Sbjct: 146 SEGRSEDFQKHFCGTHFFNPPRYLELFEIIPGPKTSPEVLDFLNGYGEKFLGKTSIVAKD 205
Query: 589 TPGFVVNRILXPYSAEALRMYERGDATKEDID 684
TP F+ NR+ M + D T E++D
Sbjct: 206 TPAFIGNRVGIFSIMSLFHMVKELDMTVEEVD 237
>UniRef50_Q128W2 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=6; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Polaromonas sp. (strain
JS666 / ATCC BAA-500)
Length = 719
Score = 94.3 bits (224), Expect = 3e-18
Identities = 49/166 (29%), Positives = 86/166 (51%)
Frame = +1
Query: 241 LDRIKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIG 420
L RI + ++ D DLIIEA+ E+ D+K + + + L A+NTS++ ++ +
Sbjct: 383 LSRITATDQLADLAGCDLIIEAVFEQRDLKAKVTQEAEPLLAAGGFFASNTSTLPISGLA 442
Query: 421 SGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGF 600
R +KF G+HFF+PV M+L+E+I+ ++T ++ +++GK I D+ GF
Sbjct: 443 VASSRPEKFIGIHFFSPVDKMKLVEIIRGRQTDDETVARAFDYVQALGKIPIVVNDSRGF 502
Query: 601 VVNRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+R + E M G + G++ AG P+GP + D
Sbjct: 503 YTSRTFAAFVMEGAAMLGEGIPAAVIENAGMQ--AGMPVGPLAVLD 546
>UniRef50_Q6SEY0 Cluster: 3-hydroxyacyl-CoA dehydrogenase domain
protein; n=1; uncultured bacterium 582|Rep:
3-hydroxyacyl-CoA dehydrogenase domain protein -
uncultured bacterium 582
Length = 322
Score = 93.9 bits (223), Expect = 4e-18
Identities = 70/225 (31%), Positives = 115/225 (51%), Gaps = 5/225 (2%)
Frame = +1
Query: 79 AQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIKI 258
A V A+AG VT+ D++ L A K + L + + DP I L RI
Sbjct: 30 AIVFARAGWQVTLQDIDLAKLQGAPKVLAVQLRMLEQHDLCADPAGI-------LARISY 82
Query: 259 STKVEDSV-NADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
+ ++ +V D + E E L +KQ+LF++LD L P TILA++TS + + + +
Sbjct: 83 ESDLKTAVCEVDYVQECGPEVLGLKQELFSELDALTPPETILASSTSGLMASQFSAHLAG 142
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITC-KDTPGFVVNR 612
+ + H NP ++ ++E+ S+ + + +++ VG+T +T K+ PGF++NR
Sbjct: 143 RHRALVAHPVNPPHLVPVVEISPSEWTDPEIVRVVVDVMTGVGQTPVTVQKEIPGFLLNR 202
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFP---MGPFXLAD 738
+ EALR+ + G AT EDID ++ G G MGPF D
Sbjct: 203 LQGALLNEALRLAQGGFATVEDIDKTVRDGLGLRWSFMGPFETID 247
>UniRef50_UPI00006A277A Cluster: UPI00006A277A related cluster; n=1;
Xenopus tropicalis|Rep: UPI00006A277A UniRef100 entry -
Xenopus tropicalis
Length = 666
Score = 93.1 bits (221), Expect = 6e-18
Identities = 52/150 (34%), Positives = 79/150 (52%)
Frame = +1
Query: 289 DLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFN 468
DL+IEA+ E + +KQD+ KL +A I+ATNTS++ V+ + R G+HFF+
Sbjct: 371 DLVIEAVFENMALKQDICAKLGAVAKPGAIIATNTSTLDVDVLARATGRSADVVGMHFFS 430
Query: 469 PVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRILXPYSAEALRM 648
P VMRLLEV++ + D +M+ +GK + GF+ NR+ Y EA +
Sbjct: 431 PAHVMRLLEVVRGAATAPDVLATIMKLAARIGKVPVVSGVCYGFIGNRMAEVYMREAEFL 490
Query: 649 YERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
G A +D ++ GF MGP + D
Sbjct: 491 IMEG-AEPAQVDAAVE-ALGFAMGPCRMLD 518
>UniRef50_Q0SJP3 Cluster: Bifunctional 3-hydroxyacyl-CoA
dehydrogenase/ 3-hydroxybutyryl-CoA epimerase; n=1;
Rhodococcus sp. RHA1|Rep: Bifunctional 3-hydroxyacyl-CoA
dehydrogenase/ 3-hydroxybutyryl-CoA epimerase -
Rhodococcus sp. (strain RHA1)
Length = 428
Score = 91.5 bits (217), Expect = 2e-17
Identities = 56/170 (32%), Positives = 88/170 (51%), Gaps = 4/170 (2%)
Frame = +1
Query: 241 LDRIKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIG 420
L RI + V D + LIIEA+ E + +KQ + ++ + T+LA+ TS++ + +
Sbjct: 93 LGRITPTECVRDLSTSALIIEAVAENVAVKQQVLQMVEAVTDAPTVLASTTSTLPIATLS 152
Query: 421 SGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGF 600
S ++R F G+HFF+PV M L+E + S+ T A + + + +GK I D+ GF
Sbjct: 153 SKLQRPQYFIGMHFFSPVDRMSLVETVVGSRTSQATVAASLTYARRLGKVPIVVGDSRGF 212
Query: 601 VVNRILXPYSAEALRMYERGDATKEDIDIGL----KLGAGFPMGPFXLAD 738
+R++ Y EAL A E ID GL AG+P+ P L D
Sbjct: 213 FTSRLMERYLDEAL------VAVGEGIDPGLVERAATAAGYPVPPLHLLD 256
>UniRef50_Q0AI36 Cluster: 3-hydroxybutyryl-CoA epimerase; n=3;
Nitrosomonadaceae|Rep: 3-hydroxybutyryl-CoA epimerase -
Nitrosomonas eutropha (strain C71)
Length = 852
Score = 91.5 bits (217), Expect = 2e-17
Identities = 51/154 (33%), Positives = 82/154 (53%), Gaps = 4/154 (2%)
Frame = +1
Query: 166 ANLGRVAKKLYKDDPGKIEGFVKES-LDRIKISTKVEDSVNADLIIEAIVEKLDIKQDLF 342
AN+ + +L K DP + + S ++ +E DL+IEAI E+L++K +L+
Sbjct: 60 ANVLKAINRLNKQDPSPLSVIDRASCIEPANYEQHLEKLGECDLVIEAITERLELKSELY 119
Query: 343 NKLDKLAPEHTILATNTSSISVNAIGSGIKR--KDKFGGLHFFNPVPVMRLLEVIKSDHI 516
K+ ILA+NTS +S+N + + + + +F G+HFFNP M L+E+I
Sbjct: 120 EKVAPYLNNQAILASNTSGLSINQLAAAVPEALRPRFCGIHFFNPPRYMYLVELIPGKQS 179
Query: 517 SEDTYQAMMEW-GKSVGKTCITCKDTPGFVVNRI 615
+ A+ + S+GK I KDTP FV NR+
Sbjct: 180 DQGVLDALESFLVTSLGKGVIHAKDTPNFVANRV 213
>UniRef50_Q68WH7 Cluster: Putative fatty acid oxidation complex
trifunctional enzyme [Includes: 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35); Enoyl-CoA
hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA
isomerase (EC 4.2.1.17) (EC 5.3.3.8)]; n=20;
Rickettsia|Rep: Putative fatty acid oxidation complex
trifunctional enzyme [Includes: 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35); Enoyl-CoA
hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA
isomerase (EC 4.2.1.17) (EC 5.3.3.8)] - Rickettsia typhi
Length = 720
Score = 91.5 bits (217), Expect = 2e-17
Identities = 65/189 (34%), Positives = 98/189 (51%), Gaps = 9/189 (4%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDL---EPEILNKAQKSIQANLGR--VAKKLYKDDPGKIE-GFVKE 237
IA + A + V ++D+ + NK K+ NL R + Y D I G ++
Sbjct: 20 IAALIANSSHRVVLLDILDKDSNDPNKIVKNAVKNLHRQKLPPLSYPDKVNFITIGNLEH 79
Query: 238 SLDRIKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAI 417
LD IK +L+IE IVEKLDIK L+NK+ E TI+A+NTS++ + +
Sbjct: 80 DLDLIK---------ECNLVIEVIVEKLDIKHQLYNKIIPYLKEDTIIASNTSTLPLKKL 130
Query: 418 GSGIKR--KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEW-GKSVGKTCITCKD 588
+ K +F HFFNP M L+E+I + I ++ + + + K +GKT I C D
Sbjct: 131 KENLPNNIKSRFIITHFFNPPRYMELVELIIDNTIKDEVIEKISVFLTKILGKTIIKCND 190
Query: 589 TPGFVVNRI 615
TPGF+ NR+
Sbjct: 191 TPGFIANRV 199
>UniRef50_A0GEI2 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Burkholderia|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Burkholderia phytofirmans
PsJN
Length = 317
Score = 91.1 bits (216), Expect = 3e-17
Identities = 62/213 (29%), Positives = 105/213 (49%), Gaps = 2/213 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKES-LDRI 252
IA +A G + D++P L QA L + D G+I+ K++ L RI
Sbjct: 31 IATQSALHGHRTIVHDVDPARLASVAPKAQAVLDELI------DAGRIDPAAKQAALARI 84
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
+ +++ +A +IEAI E L++K L+ L +L + ILA+NTS + + + ++
Sbjct: 85 ETHAELDVMASAQFVIEAIPEVLELKHRLYAALTQLLADDAILASNTSGFHPDQLAAPLR 144
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVG-KTCITCKDTPGFVVN 609
KD+F HF+NP ++ L+EV+ + + Q ++G + + K PGFV N
Sbjct: 145 AKDRFVIAHFWNPPHMIPLVEVVPGTATAPEVTQQTAALMSAIGMEPVVLAKAIPGFVGN 204
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAG 708
R+ EAL + G AT + +D +K G
Sbjct: 205 RLQFAMLREALHIVRSGAATPDVVDRVMKASLG 237
>UniRef50_Q1NHB4 Cluster: Fatty oxidation complex, alpha subunit;
n=2; Proteobacteria|Rep: Fatty oxidation complex, alpha
subunit - Sphingomonas sp. SKA58
Length = 722
Score = 90.6 bits (215), Expect = 3e-17
Identities = 64/222 (28%), Positives = 105/222 (47%), Gaps = 1/222 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKES-LDRI 252
IA V+A AG +V ++D + K + LG++ +K GK+ ++ L RI
Sbjct: 328 IAFVSANAGIDVVLIDRDTATAQKGKDYSAKVLGKLVEK------GKLTQDKADAVLARI 381
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
+ D+++EA+ E IK + K + + P I A+NTS++ ++ + +
Sbjct: 382 TPTDDFALLDGCDMVVEAVFEDTAIKAETTKKAEAVLPAQAIFASNTSTLPISQLAQASR 441
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
D+F GLHFF+PV M L+EVI S++T +++ + KT I D+ GF +R
Sbjct: 442 SPDQFIGLHFFSPVDRMGLVEVIMGKQTSKETLAKGLDFIAQLRKTPIVVNDSRGFYTSR 501
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+ E M G I+ K G P+GP L D
Sbjct: 502 VFQMLIHEGAAMLAEG-VPPAVIENAAK-AVGMPVGPLALLD 541
>UniRef50_A6DTH3 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
C-terminal domain family protein; n=1; Lentisphaera
araneosa HTCC2155|Rep: 3-hydroxyacyl-CoA dehydrogenase,
C-terminal domain family protein - Lentisphaera araneosa
HTCC2155
Length = 762
Score = 90.6 bits (215), Expect = 3e-17
Identities = 69/209 (33%), Positives = 105/209 (50%), Gaps = 5/209 (2%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEG-FVKESLDRI 252
IA A G +V ++DL + K + G V KKL K +P + V E++
Sbjct: 19 IAAHFANCGFSVALLDLT----SAGPKPSAISEGAV-KKLLKINPSPLYSPSVIENIFPG 73
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
+E ADLIIEA++E L IKQ+L++++ K ILATNTS + + I +
Sbjct: 74 NFDDHLEHLDEADLIIEAVIEDLAIKQNLWSQICKYVKADAILATNTSGLPLKDITKNLS 133
Query: 433 RKD--KFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK-SVGKTCITCKDTPGFV 603
K +F G+HFFNP +LLE+I + + E+ + +GK + KDTP F+
Sbjct: 134 NKSLKRFLGVHFFNPPRYQKLLELIPGPKTQDGLLEEFAEFARLHLGKGIVVAKDTPNFI 193
Query: 604 VNRI-LXPYSAEALRMYERGDATKEDIDI 687
NRI + ++E G T E+ID+
Sbjct: 194 GNRIGCYAMQKSMIPLFEDG-FTIEEIDL 221
>UniRef50_A3N0P8 Cluster: Putative fatty acid oxidation complex
alpha subunit; n=1; Actinobacillus pleuropneumoniae
L20|Rep: Putative fatty acid oxidation complex alpha
subunit - Actinobacillus pleuropneumoniae serotype 5b
(strain L20)
Length = 705
Score = 90.2 bits (214), Expect = 5e-17
Identities = 63/222 (28%), Positives = 108/222 (48%), Gaps = 1/222 (0%)
Frame = +1
Query: 76 IAQVTAQ-AGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRI 252
IA +TA A V I D+ P + KA ++ + + K + G + + ++ I
Sbjct: 330 IAYLTANNAKVPVRIKDIHPSEIRKALRTCFELMQKSTDKNQLN-----HGEMIQRMNLI 384
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
++ + + D +IEA+ E L +KQ + + + E TI ATNTS+ ++ I +
Sbjct: 385 TGGERLVAAKSTDFVIEAVYEDLKLKQRMLAESESYYSEQTIFATNTSTFAIKDIAACAI 444
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
R + GLH+F+PV +++E+I E T + + GK + D GF +NR
Sbjct: 445 RPENVIGLHYFSPVTTQKMVEIIPHSATGEHTIATAIHFAIQQGKIPLLVADKQGFFINR 504
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
+L P EA++ G++ E ID L+ GF +GP + D
Sbjct: 505 VLTPLLLEAVQCLIDGESI-EFIDRSLQ-EFGFKLGPLAMID 544
>UniRef50_UPI0000588BF0 Cluster: PREDICTED: similar to
3-hydroxyacyl-coa dehyrogenase; n=5; Coelomata|Rep:
PREDICTED: similar to 3-hydroxyacyl-coa dehyrogenase -
Strongylocentrotus purpuratus
Length = 316
Score = 89.4 bits (212), Expect = 8e-17
Identities = 61/214 (28%), Positives = 110/214 (51%), Gaps = 4/214 (1%)
Frame = +1
Query: 79 AQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGF--VKESLDRI 252
A + A AG +VTI D+EP ++ A K I++ L +++ G + G V+ I
Sbjct: 19 AMIFASAGFSVTIFDIEPSQVSNALKLIKSQLEELSES------GMLRGTLSVEAQFALI 72
Query: 253 KISTKVEDSV-NADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGI 429
K S +E+++ A + E + EKL++KQ +F+++++ + IL++++S I + +
Sbjct: 73 KGSNSMEEALAGASFVQECVFEKLEVKQKVFSEMEQYVSDGAILSSSSSCIMPSQFTENL 132
Query: 430 KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITC-KDTPGFVV 606
KR+++ H NP L+E+I + + +SVG+ +T K+ PGF
Sbjct: 133 KRRNQCIISHPINPPYYAPLVEIIPAPWTDQSAIDRTRTIMESVGQVPVTLKKEVPGFAA 192
Query: 607 NRILXPYSAEALRMYERGDATKEDIDIGLKLGAG 708
NRI AE R+ E G + +D+D + G G
Sbjct: 193 NRIQYAIIAEVWRLVEGGVLSADDMDKVMSAGLG 226
>UniRef50_Q392L7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=9;
Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 336
Score = 89.4 bits (212), Expect = 8e-17
Identities = 63/216 (29%), Positives = 102/216 (47%), Gaps = 5/216 (2%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDP-GKIEGFVKESL-DR 249
IA V A AG +VT++D + +A+ L+ G+I+ +++ R
Sbjct: 22 IALVFAFAGIDVTLIDFKRRDAVGQSAFDDRTRDEIARPLHAQVALGRIDAAQADAVVAR 81
Query: 250 IKISTK---VEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIG 420
I I + E +AD++ EA+ E LD K D L + +A+ TS+ V +
Sbjct: 82 IAIVARDGAAEAVRDADIVFEALPEVLDAKADALRWLGEHVDARATIASTTSTFVVTELQ 141
Query: 421 SGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGF 600
+ R ++ H+ NP +M L+E+ +SD + A+ + VGK + C PG+
Sbjct: 142 RHVVRPERMLNAHWLNPALLMPLVEISRSDATDQSVVDALAALLERVGKKPVICGPAPGY 201
Query: 601 VVNRILXPYSAEALRMYERGDATKEDIDIGLKLGAG 708
+V RI EA RM E G A+ EDID ++ G G
Sbjct: 202 IVPRIQALAMNEAARMVEEGVASAEDIDTAIRTGFG 237
>UniRef50_Q9UX37 Cluster: 3-hydroxyacyl-CoA-dehydrogenase; n=4;
Sulfolobaceae|Rep: 3-hydroxyacyl-CoA-dehydrogenase -
Sulfolobus solfataricus
Length = 324
Score = 89.4 bits (212), Expect = 8e-17
Identities = 63/215 (29%), Positives = 108/215 (50%), Gaps = 6/215 (2%)
Frame = +1
Query: 100 GQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIKISTKVEDS 279
G V + + E L KA + A L + K L G I + + + TK++D+
Sbjct: 31 GYKVNLYTEKKETLEKALAKVSAYLVNL-KNL-----GMINEEPESYITNLTGITKIDDA 84
Query: 280 V-NADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKRKDKFGGL 456
+ N D +IEAI+E K++LF LD P+ I+A++TS + + I + R + G +
Sbjct: 85 IHNVDFVIEAIIEDYTAKKNLFKLLDTQLPQDIIIASSTSGLLMTEIQKAMIRHPERGVI 144
Query: 457 -HFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITC-KDTPGFVVNRILXPYS 630
H +NP ++ L+E++ + S++T E+ + + + + K+ PGF+ NR+
Sbjct: 145 AHPWNPPHLLPLVEIVPGEKTSKETVDLTREFMEKLDRVVVLLRKEVPGFIGNRLAFALF 204
Query: 631 AEALRMYERGDATKEDIDIGLKLGAGFP---MGPF 726
EA+ + + G AT EDID + G MGPF
Sbjct: 205 REAVNLVDEGVATVEDIDKVMTAAIGLRWAFMGPF 239
>UniRef50_A1I839 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Candidatus
Desulfococcus oleovorans Hxd3
Length = 289
Score = 88.6 bits (210), Expect = 1e-16
Identities = 60/221 (27%), Positives = 106/221 (47%), Gaps = 4/221 (1%)
Frame = +1
Query: 91 AQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIKISTKV 270
A G V + D++ + L A++++ + ++ G + ES+ + I+T
Sbjct: 26 AVRGCEVILYDVKEDALEAARRAMAVKIDKMVPA------GALTPEAAESI-KANITTTT 78
Query: 271 E---DSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKRKD 441
+ +ADL+ E++ E DIK + F KL + PE TI TNTSS+ + + R D
Sbjct: 79 DLAAAGADADLVSESVPEDPDIKGEFFEKLHGVCPERTIFTTNTSSLVPSMFAARTGRPD 138
Query: 442 KFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCK-DTPGFVVNRIL 618
+F HF P +L++V+ S +T + + + + +G + I K + G++ N +L
Sbjct: 139 RFLAFHFH---PGFKLVDVMGHAGTSAETVETVRRFAERIGHSPIVLKQEKAGYLFNSLL 195
Query: 619 XPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLADY 741
P+ L + R A ED+D P+GPF L D+
Sbjct: 196 NPWLLAGLNLVSREIAAPEDVDRAWTEITAMPLGPFALMDF 236
>UniRef50_Q0SA65 Cluster: Possible 3-hydroxybutyryl-CoA
dehydrogenase; n=1; Rhodococcus sp. RHA1|Rep: Possible
3-hydroxybutyryl-CoA dehydrogenase - Rhodococcus sp.
(strain RHA1)
Length = 331
Score = 88.2 bits (209), Expect = 2e-16
Identities = 51/173 (29%), Positives = 89/173 (51%), Gaps = 3/173 (1%)
Frame = +1
Query: 229 VKESLDRIKISTKVEDSV-NADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSIS 405
+ ++ R+ ST + ++V +ADL+IEA+ E+ D+K ++ + PEHT++ATN+S++
Sbjct: 74 IAKTRKRLTYSTDISEAVQHADLVIEAVSERPDVKTSVYETMAPHLPEHTMIATNSSTLL 133
Query: 406 VNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITC- 582
+ R +K+ LHF N + + +E++ + DT A E+G +G +
Sbjct: 134 PQDFAAATGRPEKYCALHFANLIWKLNAVEIMAHPETARDTLIAATEFGIEIGMVPVPIQ 193
Query: 583 KDTPGFVVNRILXPYSAEALRMYERGDATKEDID-IGLKLGAGFPMGPFXLAD 738
K G+ +N L P A + AT ED+D + + G MGP L D
Sbjct: 194 KQQNGYAINTWLVPLLNAAQTLVTNDVATAEDVDRTYMIVNRGCSMGPLGLMD 246
>UniRef50_Q5P5K6 Cluster: Fusion of 3-hydroxyacyl-CoA dehydrogenase
and enoyl-CoA hydratase; n=20; Proteobacteria|Rep:
Fusion of 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA
hydratase - Azoarcus sp. (strain EbN1) (Aromatoleum
aromaticum (strain EbN1))
Length = 797
Score = 87.8 bits (208), Expect = 2e-16
Identities = 51/145 (35%), Positives = 77/145 (53%), Gaps = 4/145 (2%)
Frame = +1
Query: 193 LYKDDPGKIEGFVKES-LDRIKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPE 369
L K DP + V+ S +D + +E + DL+IEAI EKL+ K+DL+ K
Sbjct: 55 LTKLDPAPLAAAVRASHIDAANYDSDLERLRDCDLVIEAIAEKLEWKRDLYAKAAPYLRP 114
Query: 370 HTILATNTSSISVNAIGSGIKR--KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMM 543
I A+NTS +S+ + G+ + +F G+HFFNP M L+E+I + A+
Sbjct: 115 DAIFASNTSGLSIATLAEGLPEALRSRFCGVHFFNPPRYMALVELIPAPATDPLMLDALE 174
Query: 544 EW-GKSVGKTCITCKDTPGFVVNRI 615
W +GK+ + KDTP FV NR+
Sbjct: 175 AWLVTRLGKSIVRAKDTPNFVANRV 199
>UniRef50_Q02A28 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Solibacter usitatus Ellin6076|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Solibacter usitatus (strain Ellin6076)
Length = 309
Score = 87.4 bits (207), Expect = 3e-16
Identities = 54/163 (33%), Positives = 89/163 (54%), Gaps = 2/163 (1%)
Frame = +1
Query: 259 STKVEDSVN-ADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
ST E S+ AD++IE+ E++ KQ+LF ++D++A +LA+NTS +SV AI + R
Sbjct: 69 STDFEYSIGQADIVIESGPEEMGWKQELFARMDRVARADAVLASNTSGLSVTAIAAECAR 128
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCK-DTPGFVVNR 612
++ HF+NP ++ L+E+I+ S A+ E + GKT + K D PG + NR
Sbjct: 129 PEQVLATHFWNPPHLVPLVEIIQGRATSPAAAAAVRELLTACGKTPVVVKLDRPGQLGNR 188
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLADY 741
+ EA + G A E +D +K G G M + + ++
Sbjct: 189 LQMALVREAANIVAEGIADAEAVDSVVKNGLGIRMPAYGIFEH 231
>UniRef50_Q01UM7 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Solibacter usitatus Ellin6076|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Solibacter usitatus (strain Ellin6076)
Length = 794
Score = 87.0 bits (206), Expect = 4e-16
Identities = 55/156 (35%), Positives = 80/156 (51%), Gaps = 4/156 (2%)
Frame = +1
Query: 283 NADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR--KDKFGGL 456
+ D +IEA+ E L IKQ L +K IL TNTS + V I + + + ++ G
Sbjct: 105 DCDWVIEAVTENLAIKQSLLDKAVPHLKAGAILTTNTSGLPVAQIAAKLPADVRRRWFGT 164
Query: 457 HFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSV-GKTCITCKDTPGFVVNRILXPYSA 633
HFFNP MRLLE+I + A+ + + GK + +DTP F+ NRI
Sbjct: 165 HFFNPPRYMRLLEIIPTPDADAAAIAAISHFADVLLGKEVVFARDTPNFIANRIGVFIML 224
Query: 634 EALRMYERGDATKEDIDIGLKLGAGFP-MGPFXLAD 738
EA+R+ + D T E++D+ G+P G F LAD
Sbjct: 225 EAVRLMQEEDLTIEEVDVLTGSVIGWPRTGTFRLAD 260
>UniRef50_Q7UXV2 Cluster: Fatty oxidation complex alpha subunit;
n=1; Pirellula sp.|Rep: Fatty oxidation complex alpha
subunit - Rhodopirellula baltica
Length = 396
Score = 86.2 bits (204), Expect = 7e-16
Identities = 52/156 (33%), Positives = 80/156 (51%), Gaps = 1/156 (0%)
Frame = +1
Query: 274 DSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKRKD-KFG 450
D++ ++IE+I EKL IKQ F +++ IL TNTS++ + I ++ +F
Sbjct: 85 DALPTWVVIESIAEKLPIKQAFFAEVENWFARSPILTTNTSTLPITEIAGAMRTHSARFC 144
Query: 451 GLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRILXPYS 630
G+HFF PV E+I SE +A + + K + D+PGFVVNR+L PY
Sbjct: 145 GMHFFMPVVGRHAAEIIVHSRTSEAVIEACEGHVRRLKKAPLRVLDSPGFVVNRMLAPYL 204
Query: 631 AEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
++++ G A + L+ G PM PF L D
Sbjct: 205 NLSMQLLCAGVAASTIRESALRY--GMPMSPFELID 238
>UniRef50_Q1INT0 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=1; Acidobacteria bacterium
Ellin345|Rep: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor - Acidobacteria bacterium (strain
Ellin345)
Length = 806
Score = 86.2 bits (204), Expect = 7e-16
Identities = 49/145 (33%), Positives = 76/145 (52%), Gaps = 3/145 (2%)
Frame = +1
Query: 289 DLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR--KDKFGGLHF 462
D IIEA+VE L++K+ L K++ + +++ TNTS + V+ I G + + G HF
Sbjct: 90 DWIIEAVVENLELKRALLKKVEAVRKPGSLITTNTSGLPVSKISEGFSEDFRRNWFGTHF 149
Query: 463 FNPVPVMRLLEVIKSDHISEDTYQAMMEWGK-SVGKTCITCKDTPGFVVNRILXPYSAEA 639
FNP MRLLE+I + +A+ G +GK + KDTP F+ NRI
Sbjct: 150 FNPPRYMRLLELIPTPDTDPKAMEAVAHLGDVQLGKGIVHAKDTPNFIGNRIGTFSVLNV 209
Query: 640 LRMYERGDATKEDIDIGLKLGAGFP 714
+R+ + D + ED+D G+P
Sbjct: 210 IRVMQEMDLSIEDVDALTGSAVGWP 234
>UniRef50_Q01V22 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=1; Solibacter usitatus
Ellin6076|Rep: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor - Solibacter usitatus (strain
Ellin6076)
Length = 778
Score = 86.2 bits (204), Expect = 7e-16
Identities = 68/214 (31%), Positives = 106/214 (49%), Gaps = 11/214 (5%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IA A AG V ++DL + +K Q++ A G + K P GF ++ +
Sbjct: 20 IAAHFANAGFPVDLLDLV--LPDKPQRNALALAG--IESAAKQRP---VGFFTDAAKTLI 72
Query: 256 ISTKVEDSVN----ADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGS 423
ED + + I+EA+ E L+IK+ L+ ++ L IL+TNTS I + I +
Sbjct: 73 TPGNFEDDLGRVGRCEWIVEAVAENLEIKRALWQRVAALRAPGAILSTNTSGIPLAQISA 132
Query: 424 GIKRKDK--FGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKS-----VGKTCITC 582
G + + F G HFFNP + L EVI +T +++W S +GK + C
Sbjct: 133 GFDSEFRRHFLGTHFFNPPRYLHLAEVIPG----AETNPEVLDWVSSFCDLHLGKGVVRC 188
Query: 583 KDTPGFVVNRILXPYSAEALRMYERGDATKEDID 684
KDTP F+ NRI + A+ ++ E GD T E++D
Sbjct: 189 KDTPNFIANRIGCFFGAKIAQLTEEGDYTVEEVD 222
>UniRef50_Q46MP3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4;
Burkholderiales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Ralstonia eutropha (strain JMP134) (Alcaligenes
eutrophus)
Length = 304
Score = 85.8 bits (203), Expect = 1e-15
Identities = 49/169 (28%), Positives = 90/169 (53%), Gaps = 5/169 (2%)
Frame = +1
Query: 250 IKISTKVEDSV-NADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSG 426
+++ + ++D V + D+++EA E + K++L ++D L I+A+NTS + + I G
Sbjct: 66 VRVCSTLQDCVRDCDIVVEAAPESVSTKRELIREID-LVNSECIIASNTSVLRITEIAEG 124
Query: 427 IKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCI-TCKDTPGFV 603
+ G H++NP +M L+EV++ + E + + +W GKT + +D PGFV
Sbjct: 125 SADPGRVVGTHWWNPPYLMPLVEVVRGELTREGVAKQVSQWLSKAGKTPVDVYRDVPGFV 184
Query: 604 VNRILXPYSAEALRMYERGDATKEDIDIGLKLGAG---FPMGPFXLADY 741
NR+ EA + E+G + E +D+ +L G +GP AD+
Sbjct: 185 GNRMQFALVREAAHIVEQGICSAETVDLVARLTFGRRLAAVGPLRNADF 233
>UniRef50_A1CC71 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putative;
n=2; Aspergillus|Rep: 3-hydroxyacyl-CoA dehydrogenase,
putative - Aspergillus clavatus
Length = 307
Score = 85.8 bits (203), Expect = 1e-15
Identities = 67/223 (30%), Positives = 105/223 (47%), Gaps = 2/223 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
+ + A AG V + + PE+ A K I L + A KL GK G + +
Sbjct: 28 LCMMWAAAGHTVQLYEKSPEVAVAALKYIHEALPQQASKLLL---GKKAG---HGIGHVS 81
Query: 256 ISTKVEDSV-NADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
++ +E +V NA ++IEAI E L +K +LF +LD+LAP ILATN+SS + +
Sbjct: 82 PASSLETAVQNAWMVIEAIPELLPLKIELFGQLDQLAPADCILATNSSSYKSREMLEKVA 141
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCK-DTPGFVVN 609
R+ + H++ P P LE++ ++E + G + K ++ G + N
Sbjct: 142 RRARVCNAHYYMP-PEQNHLEIMTCGFTDPAIISFLLEQAAAAGFVPVHAKVESTGLIFN 200
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
RI EAL + E G A+ E+ID K GP + D
Sbjct: 201 RIWAAIKREALLVMEEGVASAEEIDDLFKGWFQAQAGPCEMID 243
>UniRef50_Q0RVG8 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 288
Score = 85.4 bits (202), Expect = 1e-15
Identities = 54/168 (32%), Positives = 90/168 (53%), Gaps = 5/168 (2%)
Frame = +1
Query: 250 IKISTKVEDSVN-ADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSG 426
I+ S +E +V + L+ EA+VE L++K+DLF ++++ + E T +A+NTS+ + + +
Sbjct: 49 IEASDTIEAAVEGSSLLFEAVVENLEVKRDLFAEIERFS-ESTPIASNTSTFTPSELAKN 107
Query: 427 IKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITC-KDTPGFV 603
+ + HFFNP V+ L+EV+ S D A+ + GKT + ++ PGFV
Sbjct: 108 LCEPGRLVIAHFFNPAEVVPLVEVVPSPDTRPDVVSAVTSALVAAGKTVVPLNREAPGFV 167
Query: 604 VNRILXPYSAEALRMYERGDATKEDID--IGLKLGAGF-PMGPFXLAD 738
NR+ EA+ + AT E ID + LG + GPF + D
Sbjct: 168 ANRLQAALVREAMALVRANVATAEMIDAVVTSSLGPRWAAAGPFKVMD 215
>UniRef50_A3ZZK1 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1;
Blastopirellula marina DSM 3645|Rep:
3-hydroxybutyryl-coA dehydrogenase - Blastopirellula
marina DSM 3645
Length = 319
Score = 85.4 bits (202), Expect = 1e-15
Identities = 51/193 (26%), Positives = 93/193 (48%), Gaps = 1/193 (0%)
Frame = +1
Query: 109 VTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIKISTKVEDSVNA 288
V D+ PE A+ + + L +A+ P E + +++ + +
Sbjct: 29 VVAYDINPESFAAARAHVASALEELARH-----PSVAEAIPENWPSHFQLTADLSPLGDC 83
Query: 289 DLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFN 468
D +IE+I E IKQ+ L++L P T +A+NTS++ ++ + + + + G+H+
Sbjct: 84 DFVIESIPEDPVIKQETIAALERLLPNSTPIASNTSALPISLLQAHCQLPQRIIGMHWAE 143
Query: 469 PVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGK-TCITCKDTPGFVVNRILXPYSAEALR 645
P + R LE+I+ +H + T + G+ +GK I +D PGF+VNR+ EA
Sbjct: 144 PCHLTRFLEIIRGEHTDDATADSAANLGRQLGKDPTIVQRDVPGFIVNRLAYAMYREAFW 203
Query: 646 MYERGDATKEDID 684
+ E A + ID
Sbjct: 204 LLENNVADVDTID 216
>UniRef50_A3JQP6 Cluster: Acetoacetyl-CoA reductase; n=2;
Alphaproteobacteria|Rep: Acetoacetyl-CoA reductase -
Rhodobacterales bacterium HTCC2150
Length = 780
Score = 85.4 bits (202), Expect = 1e-15
Identities = 53/184 (28%), Positives = 94/184 (51%), Gaps = 4/184 (2%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRI- 252
IA A AG V ++DL + ++ + N +L K DP + + +L ++
Sbjct: 21 IAGQIANAGHEVLLLDLPGK---NSRNEVTEN---AVTRLLKSDPPALMHKKRAALIKVG 74
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
I + D I+EAIVE+LDIK+ L+ +L+ + ++ +NTS+I + + +
Sbjct: 75 NIEDDFDKLAECDWIVEAIVERLDIKKALYQRLNDVISPECVVTSNTSTIPIKLLVEDMP 134
Query: 433 R--KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSV-GKTCITCKDTPGFV 603
+ + +F H+FNPV MRLLE+++ + + + + GK + C DTPGF+
Sbjct: 135 QDFRARFAITHYFNPVRYMRLLELVRGADTNPAVMDRLARYNDEILGKGVVQCGDTPGFL 194
Query: 604 VNRI 615
NR+
Sbjct: 195 GNRV 198
>UniRef50_Q4J0Z7 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
C-terminal:3-hydroxyacyl-CoA dehydrogenase, NAD binding
domain; n=2; Gammaproteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, C-terminal:3-hydroxyacyl-CoA
dehydrogenase, NAD binding domain - Azotobacter
vinelandii AvOP
Length = 307
Score = 85.0 bits (201), Expect = 2e-15
Identities = 53/183 (28%), Positives = 98/183 (53%), Gaps = 5/183 (2%)
Frame = +1
Query: 205 DPGKIEGFVKES-LDRIKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTIL 381
D G+ E ++ L R+ +S ++ D +A L+IEAI E+L++K+ L+ +L+ L T++
Sbjct: 55 DAGRFERAQTDATLARLAVSPRLADVADARLLIEAIPERLELKRALYAELEALVGTGTVI 114
Query: 382 ATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSV 561
A+NTS + +A+ G++ ++ HF+NP ++ L+E++ + +A+ +
Sbjct: 115 ASNTSGLPPDALAEGMRHPERLLIAHFWNPPHLIPLVEIVPGSATRAEHLEAVRTLLAGM 174
Query: 562 G-KTCITCKDTPGFVVNRILXPYSAEALRMYERGDATKEDID--IGLKLGAGFPM-GPFX 729
+ + K PGF+ NR+ EAL + G A+ E +D + LG + M GP
Sbjct: 175 ELEAVVLDKAIPGFIGNRLQFAVLREALHIVRSGAASAETVDRVMRASLGRRYAMVGPLE 234
Query: 730 LAD 738
AD
Sbjct: 235 AAD 237
>UniRef50_Q97HK2 Cluster: 3-Hydroxyacyl-CoA dehydrogenase; n=1;
Clostridium acetobutylicum|Rep: 3-Hydroxyacyl-CoA
dehydrogenase - Clostridium acetobutylicum
Length = 379
Score = 84.6 bits (200), Expect = 2e-15
Identities = 47/152 (30%), Positives = 85/152 (55%), Gaps = 1/152 (0%)
Frame = +1
Query: 244 DRIKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGS 423
D K++ ++D N D+IIEAI E +KQ++ ++K+ + ILATNTSSI + + +
Sbjct: 66 DAYKVTDNIQDLKNCDIIIEAIYEDEVLKQNILGDVEKIVKDECILATNTSSIPLEIVFA 125
Query: 424 GIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTY-QAMMEWGKSVGKTCITCKDTPGF 600
+K++ GLHFF PV ++ +E I +E Y + ++++ ++GKT + + F
Sbjct: 126 KCVKKERCLGLHFFFPVKIIDFVE-INELRCTESRYVETIVQFLTTIGKTSLDLDEKSNF 184
Query: 601 VVNRILXPYSAEALRMYERGDATKEDIDIGLK 696
V+ RIL + +Y+ + E I+ +K
Sbjct: 185 VLTRILTTIVIQIYVIYKENYLSIEQIEKEVK 216
>UniRef50_Q39D25 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=48;
Burkholderiales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 849
Score = 84.6 bits (200), Expect = 2e-15
Identities = 43/112 (38%), Positives = 65/112 (58%), Gaps = 3/112 (2%)
Frame = +1
Query: 289 DLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGI--KRKDKFGGLHF 462
D++IEAI E++D K DL+ K+ + I ATNTS +S+ + G + K +F G+HF
Sbjct: 126 DVVIEAIAERMDWKHDLYKKVAPHIAPNAIFATNTSGLSITKLSEGFSDELKSRFCGVHF 185
Query: 463 FNPVPVMRLLEVIKSDHISEDTYQAMMEWGKS-VGKTCITCKDTPGFVVNRI 615
FNP M L+E+I + H + + + S VGK + KDTP F+ NR+
Sbjct: 186 FNPPRYMHLVELIPTAHTRPEILDQLETFLTSIVGKGVVRAKDTPNFIANRV 237
>UniRef50_A4FJS5 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Saccharopolyspora erythraea NRRL
2338|Rep: 3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Saccharopolyspora erythraea (strain NRRL 23338)
Length = 659
Score = 84.6 bits (200), Expect = 2e-15
Identities = 62/221 (28%), Positives = 104/221 (47%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
IA+ AG +V +VD +P L +A + A GR ++ R++
Sbjct: 296 IARAFVSAGADVALVDRDPAALERAADQV-ARAGR------------------DAAARLR 336
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
T ++ +ADL++EA+VE +K + ++ + LATNTS + ++A+ +
Sbjct: 337 TGTALDLLSDADLVVEAVVEDHGVKAAVLGEVAGVVRPGLPLATNTSYLDIDALAATAAD 396
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRI 615
++ G+HF P +LEV++ S+D ++ + +GK + GFV NRI
Sbjct: 397 PERVLGMHFLAPAHRTGVLEVVRGRATSQDALDHVLSAARLLGKLPVIVGVCDGFVGNRI 456
Query: 616 LXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
Y + + E G AT +D L L G MGPF +AD
Sbjct: 457 FSAYRHQCELLVEEG-ATPRQVDEAL-LDVGVAMGPFAVAD 495
>UniRef50_Q160J3 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=1; Roseobacter denitrificans OCh 114|Rep: Putative
3-hydroxyacyl-CoA dehydrogenase - Roseobacter
denitrificans (strain ATCC 33942 / OCh 114)
(Erythrobactersp. (strain OCh 114)) (Roseobacter
denitrificans)
Length = 331
Score = 84.2 bits (199), Expect = 3e-15
Identities = 60/225 (26%), Positives = 116/225 (51%), Gaps = 9/225 (4%)
Frame = +1
Query: 79 AQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDR--- 249
A V +AG VT+ D ++ +A+ + + A+ + E+L+R
Sbjct: 32 ATVFLRAGMRVTLYDAASGLVEQAKAQVIERMTEFAR---------FDLVTHETLERAPA 82
Query: 250 -IKISTKVEDSVNA-DLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGS 423
I+++ +ED+V+A D I E+ E LD+K +L ++D+ A H ++ ++TS I+ +
Sbjct: 83 HIELADTLEDAVSAADYIQESGSEALDVKIELTREIDRFAAPHVVIGSSTSGITASRYSE 142
Query: 424 GIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITC-KDTPGF 600
IK +++ +H NP ++ L+EV+ + ++ + + ++G+ I ++ GF
Sbjct: 143 TIKGRERCLVVHPINPPHLVPLVEVVPAPWTAQSAVDTVHDLLSAIGQVPILLNREIDGF 202
Query: 601 VVNRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFP---MGPF 726
VVNR+ EA + ++G A+++DID + G G MGPF
Sbjct: 203 VVNRLQGALLREAFHLLDQGVASRKDIDKAISDGLGLRWSLMGPF 247
>UniRef50_Q0FMY4 Cluster: Enoyl-CoA hydratase; n=1; Roseovarius sp.
HTCC2601|Rep: Enoyl-CoA hydratase - Roseovarius sp.
HTCC2601
Length = 634
Score = 84.2 bits (199), Expect = 3e-15
Identities = 57/216 (26%), Positives = 107/216 (49%), Gaps = 1/216 (0%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEG-FVKESLDRI 252
IA A+AG V ++D + + +A+ I A L A+ D G I+G + R+
Sbjct: 306 IAMCFARAGLPVVLIDTDAAQIERARARI-AELWDQAR-----DGGGIDGPTLVAQRARL 359
Query: 253 KISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
++ST++ + +AD+++ A+ E + Q++F+ LD++ IL N +++ +++I +
Sbjct: 360 ELSTELHAAASADVVVAAVSEDMTQTQEIFSALDRICKPGAILVNNGATLDLDSIAQATR 419
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNR 612
R G+HF P +RLLEV++ + + +M + K + G V NR
Sbjct: 420 RPGDVIGMHFLQPDGAVRLLEVVRGARTAPEVIATVMALAPRLDKQPVLVGVCDGLVGNR 479
Query: 613 ILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMG 720
++ + E + E G AT + +D L G G +G
Sbjct: 480 MVRAFGREVQMLVEEG-ATPDQVDAAL-AGFGVDIG 513
>UniRef50_Q14G85 Cluster: Fusion product of 3-hydroxacyl-CoA
dehydrogenase and acyl-CoA-binding protein; n=11;
Francisella tularensis|Rep: Fusion product of
3-hydroxacyl-CoA dehydrogenase and acyl-CoA-binding
protein - Francisella tularensis subsp. tularensis
(strain FSC 198)
Length = 898
Score = 82.6 bits (195), Expect = 9e-15
Identities = 45/114 (39%), Positives = 68/114 (59%), Gaps = 3/114 (2%)
Frame = +1
Query: 283 NADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR--KDKFGGL 456
+ DLIIEA+ E++DIK+ L+ K+ E+ ILA+NTS +S+ + + K F G+
Sbjct: 197 DCDLIIEAVAERIDIKESLYTKISSHIKENAILASNTSGLSITKLAQVLPENLKVNFCGV 256
Query: 457 HFFNPVPVMRLLEVI-KSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRI 615
HFFNP M L+E+I +D SE + + +GK+ I KDTP F+ NR+
Sbjct: 257 HFFNPPRYMPLVELIPHADTNSEILDKLETFLVEKLGKSIIRAKDTPNFIANRL 310
>UniRef50_Q0LRY2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=2; Alphaproteobacteria|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Caulobacter sp. K31
Length = 348
Score = 82.6 bits (195), Expect = 9e-15
Identities = 52/160 (32%), Positives = 82/160 (51%), Gaps = 4/160 (2%)
Frame = +1
Query: 271 EDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKRKDKFG 450
E +A + E++ EKLD+K+ +F+ L + A +LA+NTS+I + I G+ + +
Sbjct: 110 EAVADAAFVFESVSEKLDVKRRIFSALAECARHDAVLASNTSAIPITQIAEGLPCEARIV 169
Query: 451 GLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITC-KDTPGFVVNRILXPY 627
G H++NP V+ L+EV+ +AMM+ SVGK + +D PGFV NR+
Sbjct: 170 GSHWWNPADVVPLVEVVPGIATDAHHVEAMMQLLISVGKKAVRIDRDIPGFVGNRLQFAL 229
Query: 628 SAEALRMYERGDATKEDIDIGLKLGAG---FPMGPFXLAD 738
EA + G E +D +K G +GP AD
Sbjct: 230 WREAQSLVANGVCDAETLDEIVKSSFGPRLSVLGPMENAD 269
>UniRef50_A5UXI1 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=6; Bacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Roseiflexus sp. RS-1
Length = 807
Score = 82.6 bits (195), Expect = 9e-15
Identities = 55/162 (33%), Positives = 88/162 (54%), Gaps = 9/162 (5%)
Frame = +1
Query: 226 FVKESLDRIKISTKVEDSV----NADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNT 393
F +S+ RI ++ VED + +AD I+EAI+E+L+ K+ L K++++ +I+++NT
Sbjct: 77 FDPQSISRI-VTGNVEDDLALIADADWIVEAIIEQLEPKRALMEKIEQVRKPGSIVSSNT 135
Query: 394 SSISVNAIGSGIKRKDKFG----GLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK-S 558
S I + AI +G R D F G HFFNP + LLEVI + A+ + +
Sbjct: 136 SGIPIAAIAAG--RSDDFRRHFLGTHFFNPPRYLYLLEVIPTPDTDPQVVAAISRFADVT 193
Query: 559 VGKTCITCKDTPGFVVNRILXPYSAEALRMYERGDATKEDID 684
+GK + CKD P F+ NRI A + R + E++D
Sbjct: 194 LGKGVVICKDRPNFIGNRIFSYDIATTVGYALRNGYSVEEVD 235
>UniRef50_A4SW21 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=1; Polynucleobacter sp.
QLW-P1DMWA-1|Rep: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor - Polynucleobacter sp.
QLW-P1DMWA-1
Length = 310
Score = 82.6 bits (195), Expect = 9e-15
Identities = 43/147 (29%), Positives = 75/147 (51%), Gaps = 1/147 (0%)
Frame = +1
Query: 274 DSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKRKDKFGG 453
D N DL+IE++ E L +K+ +F+ LD+ P H + +NTS ++ I + + +
Sbjct: 72 DWTNTDLVIESVSENLGLKRLIFSDLDQRLPSHIPIGSNTSGFPISDITASLPTAHRMFN 131
Query: 454 LHFFNPVPVMRLLEVIKSDHISEDTYQAMME-WGKSVGKTCITCKDTPGFVVNRILXPYS 630
H+F P ++ L+EV+ + + + + + K + KD PGF+ NRI
Sbjct: 132 THYFMPAHIVPLVEVVLGKTSDPELAKTVCQLFQAHHKKPVLVKKDIPGFLANRIQHALM 191
Query: 631 AEALRMYERGDATKEDIDIGLKLGAGF 711
E L + + G AT +DID ++ GF
Sbjct: 192 REVLSLVDEGIATPDDIDTAVRYSFGF 218
>UniRef50_A3VIL7 Cluster: Enoyl-CoA
hydratase/isomerase:3-hydroxyacyl-CoA dehydrogenase,3-
hydroxyacyl-CoA dehydrogenase, NAD-binding; n=1;
Rhodobacterales bacterium HTCC2654|Rep: Enoyl-CoA
hydratase/isomerase:3-hydroxyacyl-CoA dehydrogenase,3-
hydroxyacyl-CoA dehydrogenase, NAD-binding -
Rhodobacterales bacterium HTCC2654
Length = 695
Score = 82.6 bits (195), Expect = 9e-15
Identities = 56/224 (25%), Positives = 102/224 (45%), Gaps = 3/224 (1%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
+A +AG VT+ + + + + I+ G + G + G +E DR++
Sbjct: 314 VAMAALKAGVPVTVALEDDTAITRVRGRIERAFGDAV------EAGTLSG--RERDDRLR 365
Query: 256 ISTKVEDSV---NADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSG 426
+D + D+IIEA+ E K +L ++A HTI A++T+ + +
Sbjct: 366 RLNTADDYGALDDKDVIIEALAEDSVRKTQALGQLSQVAAGHTIFASSTAECDIETLAGA 425
Query: 427 IKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVV 606
R D+F +HF P RL+E+ + + ++ +++GK + G V
Sbjct: 426 SGRPDRFAAMHFIAPADANRLVEIAPARGTRPEALMTLIRLARAMGKGPVLTGARQGLVY 485
Query: 607 NRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
NR+ Y A A + E+G A ++D+ ++ G G P+GPF D
Sbjct: 486 NRMRQAYYAAAALVVEQG-ALPAEVDLAMR-GYGMPLGPFQAQD 527
>UniRef50_Q8G825 Cluster: Possible butyryl-CoA dehydrogenase; n=2;
Bifidobacterium longum|Rep: Possible butyryl-CoA
dehydrogenase - Bifidobacterium longum
Length = 319
Score = 82.2 bits (194), Expect = 1e-14
Identities = 60/210 (28%), Positives = 105/210 (50%), Gaps = 4/210 (1%)
Frame = +1
Query: 91 AQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIKISTKV 270
A AG V +V L KA K+I+++ A+ ++ + ++ V
Sbjct: 28 ALAGYPVHLVGRSEASLEKAMKAIRSDAEDFAEAGLLKAGDTVDTVLARITGYADYASGV 87
Query: 271 EDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKRKDKFG 450
D D +IE++ E LD+K+ ++ +++ AP+ IL+TNTS +S A+ S + ++F
Sbjct: 88 AD---VDFVIESVAENLDVKKSVWTEVEHAAPKDAILSTNTSGLSPTALQSVMGHPERFV 144
Query: 451 GLHFFNPVPVMRLLEVI---KSD-HISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRIL 618
HF+NP +M L+EV+ K+D + + T+ M + GK K K++ GFV NR+
Sbjct: 145 VAHFWNPAQLMPLVEVVPGEKTDPKVVDITFDLMAKIGKKPAK---IKKESLGFVGNRLQ 201
Query: 619 XPYSAEALRMYERGDATKEDIDIGLKLGAG 708
EA + ++G A +D +K G
Sbjct: 202 LAVLREAFYIVQQGIADAATVDDVMKYSLG 231
>UniRef50_A1WHE6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Verminephrobacter eiseniae EF01-2|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Verminephrobacter eiseniae (strain
EF01-2)
Length = 319
Score = 81.4 bits (192), Expect = 2e-14
Identities = 59/220 (26%), Positives = 103/220 (46%), Gaps = 3/220 (1%)
Frame = +1
Query: 88 TAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIKISTK 267
+A G++V + D+ E L + ++ QA+ + + D G E V + R+ +T
Sbjct: 23 SAFKGKSVVVYDISEEALARC-RAAQAHYAAIYQT---DAVGASEADVAGARQRLTFATD 78
Query: 268 VEDSV-NADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKRKDK 444
+ +V +ADL+IEA+ E +K ++ ++ L P HT++ATN+S+ + + R DK
Sbjct: 79 LASAVASADLVIEAVPEIPQVKTSVYQQMAPLLPAHTLIATNSSTFLPSDFAAATGRPDK 138
Query: 445 FGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITC-KDTPGFVVNRILX 621
F LH+ N + L+E++ + T + + G I K+ G+V+N
Sbjct: 139 FCALHYANYIWAANLVEIMPHAATARTTLDDVTRFAIETGMVPIPVGKEHNGYVLNAWFA 198
Query: 622 PYSAEALRMYERGDATKEDID-IGLKLGAGFPMGPFXLAD 738
P A + G T E +D L G MGP + D
Sbjct: 199 PLVTAAQALVTNGITTPEVVDRTFLIANPGARMGPMGMMD 238
>UniRef50_Q5LPZ1 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=5; Bacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase family protein - Silicibacter pomeroyi
Length = 317
Score = 80.2 bits (189), Expect = 5e-14
Identities = 48/157 (30%), Positives = 84/157 (53%), Gaps = 2/157 (1%)
Frame = +1
Query: 238 SLDRIKISTKVEDSV-NADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNA 414
SLDR+++ ++ +V A I E+ E L +KQ L+++L ++ PE+ ++ ++TS + +
Sbjct: 69 SLDRLRVVHDLDAAVAGAGFIQESAPENLAMKQALYHRLGRIVPENVVIGSSTSGLMMTD 128
Query: 415 IGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITC-KDT 591
I + + + H FNP ++ L+E++ + + E+ + GK + K+
Sbjct: 129 IQANCETPGRTVIGHPFNPPYLLPLVEIVGGERTDPAAVEWAGEFYRVAGKAPLMMKKEI 188
Query: 592 PGFVVNRILXPYSAEALRMYERGDATKEDIDIGLKLG 702
PGFV R+ EAL M G+AT EDIDI L G
Sbjct: 189 PGFVATRLQEALWREALHMVANGEATPEDIDIALMNG 225
>UniRef50_O28262 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 281
Score = 79.8 bits (188), Expect = 6e-14
Identities = 55/177 (31%), Positives = 92/177 (51%), Gaps = 3/177 (1%)
Frame = +1
Query: 220 EGFVKESLDRIKISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSS 399
E +E L +I+ +T +E + D+++EA+ E L+ K ++ ++++L + L +NTS
Sbjct: 40 EQIPEELLSKIEFTTTLEKVKDCDIVMEAVFEDLNTKVEVLREVERLT--NAPLCSNTSV 97
Query: 400 ISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCIT 579
ISV+ I + +F G+H+ NP VM L+E++ S T + + + +GK +
Sbjct: 98 ISVDDIAERLDSPSRFLGVHWMNPPHVMPLVEIVISRFTDSKTVAFVEGFLRELGKEVVV 157
Query: 580 CKDTPGFVVNRILXPYSAEALRMYERGDATKEDIDIGLK--LGAGFPM-GPFXLADY 741
CK +VNR +EA RM E G ED+D K LG + + GP DY
Sbjct: 158 CKGQS--LVNRFNAAVLSEASRMIEEG-VRAEDVDRVWKHHLGLLYTLFGPLGNLDY 211
>UniRef50_A4FKS0 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Actinomycetales|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Saccharopolyspora erythraea
(strain NRRL 23338)
Length = 303
Score = 79.4 bits (187), Expect = 9e-14
Identities = 55/167 (32%), Positives = 90/167 (53%), Gaps = 8/167 (4%)
Frame = +1
Query: 250 IKISTKVEDSVN-ADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSG 426
I+I+ + D+V+ ADL+ E E+L+ KQDLF + + AP +LA+++S I +AI
Sbjct: 57 IEIADSLADAVSDADLVQENGPERLEFKQDLFADIARHAPPRAVLASSSSGIVASAIAEH 116
Query: 427 IKRKDKFGGL---HFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITC-KDTP 594
+ D G L H FNP V+ L+E++ + E +A + ++GKT + K+ P
Sbjct: 117 LP-DDVAGRLLIAHPFNPPQVVPLVEIVPGERTEERVTEAATAFYTALGKTPVRLRKEVP 175
Query: 595 GFVVNRILXPYSAEALRMYERGDATKEDIDIGLK--LGAGF-PMGPF 726
GFV NR+ EA + G +++D +K LG + +GPF
Sbjct: 176 GFVANRLQSAVMREATHLVLEGVVRADELDTVMKSSLGGRYAAVGPF 222
>UniRef50_Q11EZ3 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=3; Bacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Mesorhizobium sp. (strain BNC1)
Length = 318
Score = 79.0 bits (186), Expect = 1e-13
Identities = 63/247 (25%), Positives = 113/247 (45%), Gaps = 5/247 (2%)
Frame = +1
Query: 13 QLLSHALKXXXXXXXXXXXXXIAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKK 192
++ SH A + A G +V I D P+ ++A +++ L +AK
Sbjct: 4 RMTSHPHASISIVGAGSIGVAFAVLFASRGASVRIWDALPDAFDRAANELRSRLEMLAKA 63
Query: 193 LYKDDPGKIEGFVKESLDRIKISTKVEDSVN-ADLIIEAIVEKLDIKQDLFNKLDKLAPE 369
+P E RI + ++++ ADL+ E E +D+K DLF L L P+
Sbjct: 64 SALSEPPD------EISSRISWHRNLAEALDGADLVQECAPENIDLKVDLFRWLADLTPD 117
Query: 370 HTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMME- 546
H +LA+++S++ + I I+ + + H NP ++ ++EV+ S ++ E
Sbjct: 118 HVVLASSSSALIASLIAPDIEIRRRVLVGHPGNPPYLIPVIEVVPSPETAQAIIDRAFEI 177
Query: 547 WGKSVGKTCITCKDTPGFVVNRILXPYSAEALRMYERGDATKEDIDIGLKLGAG---FPM 717
+ S K + ++ GF+ NR+ EA + G A+ +DID ++ G G +
Sbjct: 178 YRNSHLKPVLVRREVEGFIFNRLQGAVLREAYCLVRDGIASVDDIDEVMRSGLGRRWSVI 237
Query: 718 GPFXLAD 738
GPF AD
Sbjct: 238 GPFETAD 244
>UniRef50_Q0FUM2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Rhodobacterales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Roseovarius sp. HTCC2601
Length = 220
Score = 79.0 bits (186), Expect = 1e-13
Identities = 40/127 (31%), Positives = 74/127 (58%), Gaps = 4/127 (3%)
Frame = +1
Query: 292 LIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNP 471
L+ EA+ E L++KQ LF +L+++ PE+ +LATNTSS ++ I + + RK++ G+H+ P
Sbjct: 92 LVHEAVQESLEVKQALFAELERICPENVVLATNTSSFLISDIAAQMTRKERMMGIHYVTP 151
Query: 472 VPVMRLLEVIKSDHISEDTYQAMMEWGK----SVGKTCITCKDTPGFVVNRILXPYSAEA 639
++ ++E+I + DT ++ W + ++ + + PGF+VNRI E
Sbjct: 152 GHIVPVIELIH----AADTPAELVAWSRMLVQNIEHVGVAILERPGFLVNRIQFAMLTEI 207
Query: 640 LRMYERG 660
R+ + G
Sbjct: 208 YRLMDEG 214
>UniRef50_A6C4K6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Planctomyces maris DSM 8797|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Planctomyces maris DSM 8797
Length = 311
Score = 79.0 bits (186), Expect = 1e-13
Identities = 53/209 (25%), Positives = 107/209 (51%), Gaps = 3/209 (1%)
Frame = +1
Query: 91 AQAGQNVTIVDLEPEILNKAQKSIQANLGRVA--KKLYKDDPGKIEGFVKESLDRIKIST 264
A G V I D+ + +AQ+ NL R+A + + + D E E L+ + +
Sbjct: 21 AAQGLRVRIFDVNNTVKQQAQELSVQNLQRLADLELISRKDAATAE----EKLN--VVDS 74
Query: 265 KVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKRKDK 444
E + + + E+++E +IK D++ + ++ APE IL +++S + + + + ++ +
Sbjct: 75 LAELLTDVEYVQESVIEDYEIKADVYQQFEQYAPEAAILGSSSSGLLMTRMQTVMQHPGR 134
Query: 445 FGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGK-TCITCKDTPGFVVNRILX 621
H FNP ++ L+E++ + + +T + + E+ + +GK I ++ PG + NR+
Sbjct: 135 ALIAHPFNPPHLIPLVELVPGEQTATETMETVKEFFQGLGKHPVILNREVPGHIANRLAA 194
Query: 622 PYSAEALRMYERGDATKEDIDIGLKLGAG 708
E+L + + G A+ EDID L G G
Sbjct: 195 AVWRESLSLLDAGVASVEDIDAALCKGPG 223
>UniRef50_Q092W5 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerase family protein; n=2;
Cystobacterineae|Rep: 3-hydroxyacyl-CoA
dehydrogenase/enoyl-CoA hydratase/isomerase family
protein - Stigmatella aurantiaca DW4/3-1
Length = 797
Score = 78.6 bits (185), Expect = 1e-13
Identities = 53/175 (30%), Positives = 87/175 (49%), Gaps = 4/175 (2%)
Frame = +1
Query: 172 LGRVAKKLYKDDPGKIEGF-VKESLDRIKISTKVEDSVNADLIIEAIVEKLDIKQDLFNK 348
LG +A L K P I V SL+ + + D +IE + E L +KQ LF K
Sbjct: 58 LGALAN-LRKQKPSPIVSEQVFASLEVGNLEDDIARIAECDWVIEVVKEDLAVKQALFEK 116
Query: 349 LDKLAPEHTILATNTSSISVNAI--GSGIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISE 522
++K + I+++NTS +S+ + G G + + +F HFFNPV M+LLE++
Sbjct: 117 VEKHLRKDAIVSSNTSGLSIAGMLQGRGPEFRKRFLVTHFFNPVRYMKLLELVAGPETDP 176
Query: 523 DTYQAMMEWGKSV-GKTCITCKDTPGFVVNRILXPYSAEALRMYERGDATKEDID 684
+ + +G+ V GK + KDT F+ NRI + ++ + T E++D
Sbjct: 177 AVVRTLHAFGEGVLGKGIVYGKDTTNFIANRIGVYGMMRTIAEMQKAELTVEEVD 231
>UniRef50_A7HED1 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=4; Deltaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase NAD-binding -
Anaeromyxobacter sp. Fw109-5
Length = 795
Score = 77.8 bits (183), Expect = 3e-13
Identities = 67/220 (30%), Positives = 106/220 (48%), Gaps = 17/220 (7%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLG------RVAKK----LYKDDPGKIEG 225
IA A AG V ++D+ P+ ++ +++ LG R+A L + P +
Sbjct: 19 IAAHLANAGFRVLLLDVVPKEPSEEERAAGLGLGDRAVRDRIAAAGRAGLERLKPAPL-- 76
Query: 226 FVKESLDRIKISTKVEDSV---NADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTS 396
++ E RI++ +D + D +IE +VE L +KQ L ++ +L+TNTS
Sbjct: 77 YLPEHAGRIEVGNLEDDLPRLRDRDWVIEVVVEDLAVKQQLLGRVAAHLRPDAVLSTNTS 136
Query: 397 SISVNAIGSGIKR--KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGK-SVGK 567
+SVNA+ + + + HFFNP MRL+E++ S M E + +GK
Sbjct: 137 GLSVNALAESLPEPLRPRLLVTHFFNPPRYMRLVELVSSRFTDRAVAARMAELLRVRLGK 196
Query: 568 TCITCKDTPGFVVNRILXPYSAEAL-RMYERGDATKEDID 684
++ KDTP FV NRI AL M E G T E++D
Sbjct: 197 GVVSAKDTPNFVANRIGVFSLCNALHHMVELG-LTVEEVD 235
>UniRef50_A1B712 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=2; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Paracoccus denitrificans (strain Pd 1222)
Length = 765
Score = 77.4 bits (182), Expect = 3e-13
Identities = 52/156 (33%), Positives = 81/156 (51%), Gaps = 4/156 (2%)
Frame = +1
Query: 283 NADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR--KDKFGGL 456
+AD I+EA+ E+L +KQ L+ +L + +IL++NTS+I + A+ G+ F
Sbjct: 77 DADWIVEALPERLALKQSLYRQLQGIRKPGSILSSNTSTIPLAALVGGMAGDFAADFLIT 136
Query: 457 HFFNPVPVMRLLEVIKSDHISEDTYQAMMEW-GKSVGKTCITCKDTPGFVVNRILXPYSA 633
HFFNP MRLLE++ + + ++ + +GK ++C+DTPGF+ NRI +
Sbjct: 137 HFFNPPRRMRLLELVAGPATRPEIVALITDFCDRRLGKDVVSCRDTPGFIANRIGNYWMI 196
Query: 634 EALRMYERGDATKEDIDIGLKLGAGFP-MGPFXLAD 738
A R ED D + G P G F L D
Sbjct: 197 TAQNEAIRLGLDIEDADAIIGRPFGIPATGIFGLMD 232
>UniRef50_UPI00005102FD Cluster: COG1250: 3-hydroxyacyl-CoA
dehydrogenase; n=1; Brevibacterium linens BL2|Rep:
COG1250: 3-hydroxyacyl-CoA dehydrogenase -
Brevibacterium linens BL2
Length = 311
Score = 76.6 bits (180), Expect = 6e-13
Identities = 46/166 (27%), Positives = 86/166 (51%), Gaps = 3/166 (1%)
Frame = +1
Query: 220 EGFVKESLDRIKISTKVEDSV-NADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTS 396
EG + +++R+ + + +SV +AD + E E+LDIKQ + + D P I+A++TS
Sbjct: 56 EGDITSAMERLHFAGSLAESVGDADFVQENGPERLDIKQSMLAETDSAVPASAIIASSTS 115
Query: 397 SISVNAIGS-GIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTC 573
+ + + + ++ H FNP ++ L+E++ + + + +E +S+GK
Sbjct: 116 GFAPSELATKATNHPERIVVGHPFNPAHLVPLVELVPTPATPAEVVKRGLEIYRSIGKKP 175
Query: 574 ITCK-DTPGFVVNRILXPYSAEALRMYERGDATKEDIDIGLKLGAG 708
I + + PG V NR+ EA + +RG + EDID + G G
Sbjct: 176 ILVRAELPGHVTNRLQAALWQEAYSLVDRGMVSVEDIDTAISYGPG 221
>UniRef50_Q8FRN7 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=1; Corynebacterium efficiens|Rep: Putative
3-hydroxyacyl-CoA dehydrogenase - Corynebacterium
efficiens
Length = 755
Score = 76.2 bits (179), Expect = 8e-13
Identities = 69/233 (29%), Positives = 109/233 (46%), Gaps = 11/233 (4%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDL---EPEILNK-AQKSIQANLGRVAKKLYKDDPGKIEGFVKESL 243
IA + A AG VT++D +PE N+ A+ ++ + R A Y+ E
Sbjct: 27 IATLLANAGITVTLLDRHSGDPEDPNRLAESGLERQIQRGA--FYRP----------EFS 74
Query: 244 DRIKISTKVEDSV---NADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNA 414
RI+ V+D+ AD IIEA+ E L +K D F +++ +++++NTS+I +
Sbjct: 75 SRIQTGNIVDDTAALTRADWIIEAVFEDLTVKHDTFRLIEEHRSPGSLVSSNTSTIPLAQ 134
Query: 415 IGS--GIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMME-WGKSVGKTCITCK 585
+ G + F +HFFNP MRL+E++ + T + + +GK + C+
Sbjct: 135 LTEVMGTPMRLDFAIVHFFNPPTTMRLVELVTGPDTTPKTATDLTRIIEQQLGKVVLHCR 194
Query: 586 DTPGFVVNRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFP-MGPFXLADY 741
DTPGF+ NRI + A R + E D G P G F L DY
Sbjct: 195 DTPGFIANRIGNLWMAAGARHALDNNIPIELADALFGRPFGVPRTGIFGLFDY 247
Score = 32.7 bits (71), Expect = 9.7
Identities = 13/24 (54%), Positives = 18/24 (75%)
Frame = +1
Query: 667 TKEDIDIGLKLGAGFPMGPFXLAD 738
T E+ID+ ++LG G+ GPF LAD
Sbjct: 363 TVEEIDLAMQLGYGWKKGPFALAD 386
>UniRef50_A1IFR8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Candidatus
Desulfococcus oleovorans Hxd3
Length = 304
Score = 76.2 bits (179), Expect = 8e-13
Identities = 57/224 (25%), Positives = 101/224 (45%), Gaps = 3/224 (1%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGF-VKESLDRI 252
I + A G I DL P +L+ A+K ++ GR + ++ G ++ R+
Sbjct: 24 IGFLCAAKGFETAIYDLSPPLLDTAKKRLEKLAGRFVSR------HRLTGEEAAAAMARV 77
Query: 253 KISTKVEDSV-NADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGI 429
++ E + NAD I E++ E ++IK +F L P I TNTSS+ + + +
Sbjct: 78 TLTPDSEQAAANADFISESVTESVEIKCRVFETFHPLCPARAIFTTNTSSLIPSMLTHAV 137
Query: 430 KRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITC-KDTPGFVV 606
R D+F HF N + +++++ + +T + + + +G+ I K+ G+
Sbjct: 138 GRPDRFAAFHFHNTL-TSDIVDIMPHPGTTPETAETIRAFALRLGQVPIVFKKENHGYAF 196
Query: 607 NRILXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
N +L AL + G A EDID +GPF + D
Sbjct: 197 NALLMNLCDTALFLAAGGVAAIEDIDRSWMGIMHMKVGPFGIMD 240
>UniRef50_Q8KUG1 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=8;
Actinomycetales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Actinosynnema pretiosum subsp. auranticum
Length = 341
Score = 75.8 bits (178), Expect = 1e-12
Identities = 56/221 (25%), Positives = 94/221 (42%)
Frame = +1
Query: 76 IAQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAKKLYKDDPGKIEGFVKESLDRIK 255
I + G V +VD + + L+ A+ ++A+L R A+ L G L +
Sbjct: 72 ITALALSRGLPVLLVDPDADRLDAARADVRAHL-RTAQLL---------GVAAGPLGELT 121
Query: 256 ISTKVEDSVNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
+T ++EA+ E + K + P T L +NTSSI + + + R
Sbjct: 122 TATDTGGPREVVAVVEAVTEDAETKAKALTGVCATVPPGTPLVSNTSSIPMGELAPALPR 181
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRI 615
G HF NP ++ +EV + S+ + + +G+ + D PGFV +R+
Sbjct: 182 PGDLVGAHFMNPPYLIPAVEVARGPLTSDAAFAGLTALLARLGRAPVQVGDAPGFVTSRL 241
Query: 616 LXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
L P +A R+ E G A +D ++ G GP AD
Sbjct: 242 LHPMINDAARVVESGTADAAAVDALMRDCLGHREGPLRTAD 282
>UniRef50_A5A8P0 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 284
Score = 75.8 bits (178), Expect = 1e-12
Identities = 56/192 (29%), Positives = 97/192 (50%), Gaps = 5/192 (2%)
Frame = +1
Query: 148 AQKSIQANLGRVAKKLYK-DDPGKIEGFVK--ESLDRIKISTKVEDSV-NADLIIEAIVE 315
++K +Q L V K L K D+ G G + E+L R+ +T + + + NA + E+ +E
Sbjct: 5 SEKQLQVALENVEKNLRKLDEHGLQRGNLSADEALLRVSTTTSLNEVMKNAIYMQESALE 64
Query: 316 KLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNPVPVMRLLE 495
L+ + + +D++A TILA++TS+I + G+ K++ +H NP + L E
Sbjct: 65 DLNFRIQFYKVIDEIADPTTILASSTSTIPASKFTDGLINKERCLIVHPVNPPLFLPLTE 124
Query: 496 VIKSDHISEDTYQAMMEWGKSVGKTCITC-KDTPGFVVNRILXPYSAEALRMYERGDATK 672
++ + S+DT E +SV + + K+ GFVVNR+ AE R+ G
Sbjct: 125 LVPAPWTSQDTVDRAAEIMRSVKQEPVKLKKEVLGFVVNRLQFALLAETWRLVADGVIGV 184
Query: 673 EDIDIGLKLGAG 708
D+D + G G
Sbjct: 185 NDVDAVMSAGLG 196
>UniRef50_Q5V581 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Haloarcula marismortui|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Haloarcula marismortui (Halobacterium
marismortui)
Length = 290
Score = 75.8 bits (178), Expect = 1e-12
Identities = 45/161 (27%), Positives = 89/161 (55%), Gaps = 1/161 (0%)
Frame = +1
Query: 259 STKVEDSVN-ADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKR 435
+T +E +V+ +D++I+A + +++ + + + + TI+A + +S+SV A+ +G++
Sbjct: 58 TTGLESAVSGSDVVIDATNGGTESHREVVAETETMVEDETIIAVSDTSLSVTAVATGLRS 117
Query: 436 KDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITCKDTPGFVVNRI 615
D+ GL+ +P P ++EV+ ++ + T + ++ +S+ + + +DTPGF R+
Sbjct: 118 PDRAVGLNLVDP-PDGAIVEVVIAEQTTAATRDRVTDFVESLDASPVVVRDTPGFAALRL 176
Query: 616 LXPYSAEALRMYERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
AEA+RM E G A DID + G GP AD
Sbjct: 177 ELAAIAEAIRMVEDGVAGIRDIDRTFERGESDRDGPLVRAD 217
>UniRef50_A5V325 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Sphingomonas wittichii RW1|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Sphingomonas wittichii RW1
Length = 322
Score = 75.4 bits (177), Expect = 1e-12
Identities = 43/154 (27%), Positives = 81/154 (52%), Gaps = 2/154 (1%)
Frame = +1
Query: 247 RIKISTKVEDSVNA-DLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGS 423
R+ +ED+V D + E E+ D+K+ LF +LD+L P ++ ++TSS+ ++ + +
Sbjct: 75 RLSFHETIEDAVEGTDFVQENTPERSDVKRALFAELDRLVPADVLVGSSTSSLPISDLQA 134
Query: 424 GIKRKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITC-KDTPGF 600
G+ +F H FNPV ++ L+EV D + + ++GK + ++ G
Sbjct: 135 GLSTAARFVLGHPFNPVHLIPLVEVGGGDATDPAAVDTALAFYAALGKEPVRLNREVFGH 194
Query: 601 VVNRILXPYSAEALRMYERGDATKEDIDIGLKLG 702
+ NR+ EA+R+ G A+ ED+D ++ G
Sbjct: 195 IGNRLTSAMFREAVRLVAEGYASVEDVDKAIRFG 228
>UniRef50_A0PRD1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase FadB3;
n=1; Mycobacterium ulcerans Agy99|Rep:
3-hydroxybutyryl-CoA dehydrogenase FadB3 - Mycobacterium
ulcerans (strain Agy99)
Length = 294
Score = 74.9 bits (176), Expect = 2e-12
Identities = 43/150 (28%), Positives = 70/150 (46%), Gaps = 1/150 (0%)
Frame = +1
Query: 292 LIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKRKDKFGGLHFFNP 471
L +E++ EKL+IK L+ ++D+ AP TI ATN+SS + ++ K + HF+ P
Sbjct: 91 LAVESVPEKLEIKTALWGQIDQAAPPDTIFATNSSSFPSRLMADNVRDKTRLCNTHFYMP 150
Query: 472 VPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITC-KDTPGFVVNRILXPYSAEALRM 648
P L+++ ++ G ++ GF+ NR+ E+L +
Sbjct: 151 -PQFNALDLMSDGETDRGLLDTLLTVLPEFGVHPFEARRECTGFIFNRVWAAIKRESLAV 209
Query: 649 YERGDATKEDIDIGLKLGAGFPMGPFXLAD 738
G A ED+D K+ P GPF L D
Sbjct: 210 VAEGVARPEDVDGMFKVNWRVPAGPFQLMD 239
>UniRef50_A3M445 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=1; Acinetobacter baumannii ATCC 17978|Rep: Putative
3-hydroxyacyl-CoA dehydrogenase - Acinetobacter
baumannii (strain ATCC 17978 / NCDC KC 755)
Length = 233
Score = 74.5 bits (175), Expect = 2e-12
Identities = 41/144 (28%), Positives = 73/144 (50%), Gaps = 1/144 (0%)
Frame = +1
Query: 280 VNADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIKRKDKFGGLH 459
+N D I E E+LD+KQ+L+ ++ PE T++A+++S + V+ ++ H
Sbjct: 2 INVDFIQENAPERLDLKQNLYQEITSYCPEKTLIASSSSGLKVSDFQKDATHPERIFLGH 61
Query: 460 FFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKTCITC-KDTPGFVVNRILXPYSAE 636
FNP ++ L+E++ + E+ +S+GK I K+ G V NR+ E
Sbjct: 62 PFNPPHLLPLVEIVGGKLTDPQILKKASEFYQSLGKHPIVLNKEVKGHVANRLQAALWRE 121
Query: 637 ALRMYERGDATKEDIDIGLKLGAG 708
A + + G + ED+DI + G G
Sbjct: 122 AFSLVKEGVCSAEDVDIAITSGPG 145
>UniRef50_A1FMQ0 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=3; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Pseudomonas putida W619
Length = 320
Score = 74.5 bits (175), Expect = 2e-12
Identities = 60/226 (26%), Positives = 110/226 (48%), Gaps = 6/226 (2%)
Frame = +1
Query: 79 AQVTAQAGQNVTIVDLEPEILNKAQKSIQANLGRVAK-KLYKDDPGKIEGFVKESLDRIK 255
A V A+AG V + D++ + + + I+A L +A+ L D P + L RI
Sbjct: 27 AIVFARAGHPVRLHDMDLQTMQNSHAYIEARLNELAEFDLLNDAPLTV-------LARIT 79
Query: 256 ISTKVEDSV-NADLIIEAIVEKLDIKQDLFNKLDKLAPEHTILATNTSSISVNAIGSGIK 432
+ D++ + L+ E + E ++ K D+F+++D LAP+ ILA++TS + + +
Sbjct: 80 CVPDLADALRDVVLVQENVRETVEAKIDIFSRMDALAPKDAILASSTSWLPASEFTKDLP 139
Query: 433 RKDKFGGLHFFNPVPVMRLLEVIKSDHISEDTYQAMMEWGKSVGKT-CITCKDTPGFVVN 609
+ + H NP ++ L+E+ + + E + G++ + ++ GF++N
Sbjct: 140 GRGRCVVAHPTNPPYLVPLVELCPAPWTESEVMVRAHEIYTAAGQSPVVLSREIHGFLLN 199
Query: 610 RILXPYSAEALRMYERGDATKEDIDIGLKLGAGFP---MGPFXLAD 738
R+ E +++E G A+ EDID LK G MGPF D
Sbjct: 200 RVQAAVLNECFKLHEEGFASSEDIDRVLKDGLALRWSFMGPFETID 245
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 754,265,901
Number of Sequences: 1657284
Number of extensions: 16330755
Number of successful extensions: 49732
Number of sequences better than 10.0: 326
Number of HSP's better than 10.0 without gapping: 47298
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 49452
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 60500186565
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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