Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P07_F_B11
(793 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q75WU0 Cluster: Furin-like convetase; n=1; Bombyx mori|... 326 5e-88
UniRef50_P26016 Cluster: Furin-like protease 1, isoforms 1/1-X/2... 129 4e-38
UniRef50_Q16926 Cluster: Vitellogenin convertase; n=4; Coelomata... 117 3e-25
UniRef50_Q5QDM4 Cluster: Subtilisin-like proprotein convertase; ... 111 3e-23
UniRef50_P09958 Cluster: Furin precursor; n=55; Euteleostomi|Rep... 101 2e-20
UniRef50_P30432 Cluster: Furin-like protease 2 precursor; n=13; ... 91 2e-17
UniRef50_Q9Y1A6 Cluster: Furin1-X; n=8; Fungi/Metazoa group|Rep:... 89 9e-17
UniRef50_A3QQQ2 Cluster: Furin-2; n=3; Limulidae|Rep: Furin-2 - ... 87 4e-16
UniRef50_Q26489 Cluster: Endoprotease FURIN; n=5; Endopterygota|... 85 3e-15
UniRef50_P29122 Cluster: Proprotein convertase subtilisin/kexin ... 70 6e-15
UniRef50_Q17124 Cluster: Subtilisin-related protease SPC3; n=6; ... 82 2e-14
UniRef50_P29146 Cluster: PC3-like endoprotease variant A precurs... 81 3e-14
UniRef50_Q26352 Cluster: Lfur2; n=3; Gastropoda|Rep: Lfur2 - Lym... 75 2e-12
UniRef50_Q9NJ15 Cluster: Proprotein convertase subtilisin/kexin ... 75 3e-12
UniRef50_UPI0000E47C72 Cluster: PREDICTED: similar to furin1-X; ... 73 6e-12
UniRef50_Q069L1 Cluster: Proprotein convertase subtilisin/kexin ... 71 3e-11
UniRef50_Q6UW60 Cluster: Proprotein convertase subtilisin/kexin ... 71 3e-11
UniRef50_P41413 Cluster: Proprotein convertase subtilisin/kexin ... 70 6e-11
UniRef50_Q92824 Cluster: Proprotein convertase subtilisin/kexin ... 68 3e-10
UniRef50_Q5EE48 Cluster: Proprotein convertase 6B; n=22; Coeloma... 67 4e-10
UniRef50_Q069L0 Cluster: Proprotein convertase subtilisin/kexin ... 66 7e-10
UniRef50_A7T2M8 Cluster: Predicted protein; n=2; Nematostella ve... 65 2e-09
UniRef50_A7SSI6 Cluster: Predicted protein; n=2; Nematostella ve... 64 4e-09
UniRef50_P29120 Cluster: Neuroendocrine convertase 1 precursor; ... 60 5e-08
UniRef50_Q4SQ87 Cluster: Chromosome 4 SCAF14533, whole genome sh... 54 3e-06
UniRef50_Q4S7D2 Cluster: Chromosome 13 SCAF14715, whole genome s... 54 3e-06
UniRef50_Q10575 Cluster: Prohormone convertase 2; n=5; Chromador... 54 3e-06
UniRef50_A7RME4 Cluster: Predicted protein; n=2; Nematostella ve... 53 7e-06
UniRef50_Q16971 Cluster: PC1B protein; n=2; Aplysia californica|... 52 2e-05
UniRef50_Q4SII7 Cluster: Chromosome 5 SCAF14581, whole genome sh... 52 2e-05
UniRef50_P16519 Cluster: Neuroendocrine convertase 2 precursor; ... 49 3e-05
UniRef50_Q17325 Cluster: CelfurPC protein; n=4; Chromadorea|Rep:... 50 9e-05
UniRef50_O17798 Cluster: Putative uncharacterized protein kpc-1;... 50 9e-05
UniRef50_UPI0000DB7713 Cluster: PREDICTED: similar to proprotein... 48 2e-04
UniRef50_UPI0000DB7774 Cluster: PREDICTED: similar to Furin-like... 47 5e-04
UniRef50_Q9TTF8 Cluster: Furin; n=1; Ateles belzebuth chamek|Rep... 46 8e-04
UniRef50_UPI0000ECC1D3 Cluster: Proprotein convertase PC6; n=2; ... 44 0.004
UniRef50_Q4S7D1 Cluster: Chromosome 13 SCAF14715, whole genome s... 43 0.010
UniRef50_P51559 Cluster: Endoprotease bli-4 precursor; n=13; Chr... 42 0.013
UniRef50_UPI0000E24E64 Cluster: PREDICTED: similar to proprotein... 41 0.031
UniRef50_UPI00005884A1 Cluster: PREDICTED: similar to GA10554-PA... 41 0.031
UniRef50_UPI0000EB1075 Cluster: Furin precursor (EC 3.4.21.75) (... 41 0.041
UniRef50_UPI0000E48CE0 Cluster: PREDICTED: similar to subtilisin... 38 0.38
UniRef50_Q967D4 Cluster: Multiadhesive protein; n=1; Geodia cydo... 36 0.88
UniRef50_A0ND65 Cluster: ENSANGP00000030184; n=1; Anopheles gamb... 36 0.88
UniRef50_Q16549 Cluster: Proprotein convertase subtilisin/kexin ... 36 1.2
UniRef50_Q9VBC7 Cluster: CG6438-PA; n=44; Coelomata|Rep: CG6438-... 35 2.0
UniRef50_Q8I4G1 Cluster: Putative uncharacterized protein; n=2; ... 34 3.6
UniRef50_Q3SLV0 Cluster: Putative diguanylate cyclase/phosphodie... 33 8.2
>UniRef50_Q75WU0 Cluster: Furin-like convetase; n=1; Bombyx
mori|Rep: Furin-like convetase - Bombyx mori (Silk moth)
Length = 765
Score = 326 bits (800), Expect = 5e-88
Identities = 150/177 (84%), Positives = 150/177 (84%)
Frame = +2
Query: 263 MARGXXXXXXXXXXXXHIETTLGHYTPTWAVHIPEGREVADAVARDHGFVNLGKIFDDHY 442
MARG HIETTLGHYTPTWAVHIPEGREVADAVARDHGFVNLGKIFDDHY
Sbjct: 1 MARGVLVLSILVSVLSHIETTLGHYTPTWAVHIPEGREVADAVARDHGFVNLGKIFDDHY 60
Query: 443 HFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKRDFQIISTLYSTAETRTSE 622
HFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKRDFQIISTLYSTAETRTSE
Sbjct: 61 HFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKRDFQIISTLYSTAETRTSE 120
Query: 623 PXXXXXXXXXXXXXXELNTRIRGRTRSADLKFILNDPKWPHMWYLNRGGGLXMNVIP 793
P ELNTRIRGRTRSADLKFILNDPKWPHMWYLNRGGGL MNVIP
Sbjct: 121 PSSSAASKRDADRKRELNTRIRGRTRSADLKFILNDPKWPHMWYLNRGGGLDMNVIP 177
>UniRef50_P26016 Cluster: Furin-like protease 1, isoforms 1/1-X/2
precursor; n=9; Eumetazoa|Rep: Furin-like protease 1,
isoforms 1/1-X/2 precursor - Drosophila melanogaster
(Fruit fly)
Length = 1269
Score = 129 bits (311), Expect(2) = 4e-38
Identities = 57/84 (67%), Positives = 66/84 (78%), Gaps = 1/84 (1%)
Frame = +2
Query: 326 LGHYTPTWAVHIPEGRE-VADAVARDHGFVNLGKIFDDHYHFHHRSLTKRSLTPAHEHHG 502
+GHYT TWAVHIP G +ADAVA+DHGFVNLGKIFDDHYHF H ++KRSL+PA H
Sbjct: 228 VGHYTHTWAVHIPNGDNGMADAVAKDHGFVNLGKIFDDHYHFAHHKVSKRSLSPATHHQT 287
Query: 503 RLEGDSRVRWAEQQKILSRKKRDF 574
RL+ D RV WA+QQ+ SR KRDF
Sbjct: 288 RLDDDDRVHWAKQQRAKSRSKRDF 311
Score = 52.4 bits (120), Expect(2) = 4e-38
Identities = 23/39 (58%), Positives = 24/39 (61%)
Frame = +2
Query: 677 TRIRGRTRSADLKFILNDPKWPHMWYLNRGGGLXMNVIP 793
+R R S ND KWP MWYLNRGGGL MNVIP
Sbjct: 317 SRTSSRAMSMVDAMSFNDSKWPQMWYLNRGGGLDMNVIP 355
>UniRef50_Q16926 Cluster: Vitellogenin convertase; n=4;
Coelomata|Rep: Vitellogenin convertase - Aedes aegypti
(Yellowfever mosquito)
Length = 1060
Score = 117 bits (282), Expect = 3e-25
Identities = 53/91 (58%), Positives = 65/91 (71%), Gaps = 1/91 (1%)
Frame = +2
Query: 329 GHYTPTWAVHIPEGR-EVADAVARDHGFVNLGKIFDDHYHFHHRSLTKRSLTPAHEHHGR 505
GHYT WAVHIPEG E A+ VA +HGF+N GKIFD +YHF HR L KRSL P+ H R
Sbjct: 135 GHYTHHWAVHIPEGGGETAEQVADEHGFINHGKIFDGYYHFEHRHLQKRSLNPSGHHQRR 194
Query: 506 LEGDSRVRWAEQQKILSRKKRDFQIISTLYS 598
L+GD R RWA+QQ+ R KRDF+ + + Y+
Sbjct: 195 LDGDDRDRWAKQQRAKRRPKRDFRPLKSPYT 225
Score = 50.8 bits (116), Expect = 4e-05
Identities = 20/24 (83%), Positives = 20/24 (83%)
Frame = +2
Query: 722 LNDPKWPHMWYLNRGGGLXMNVIP 793
LNDPKW MWYLNRG GL MNVIP
Sbjct: 228 LNDPKWGEMWYLNRGNGLDMNVIP 251
>UniRef50_Q5QDM4 Cluster: Subtilisin-like proprotein convertase;
n=2; Coelomata|Rep: Subtilisin-like proprotein
convertase - Haematobia irritans (Horn fly)
Length = 988
Score = 111 bits (266), Expect = 3e-23
Identities = 51/83 (61%), Positives = 60/83 (72%), Gaps = 2/83 (2%)
Frame = +2
Query: 332 HYTPTWAVHIPEGRE--VADAVARDHGFVNLGKIFDDHYHFHHRSLTKRSLTPAHEHHGR 505
HYT TWAVHIP G AD VA++HGFVNLGKI DDHY F H + KRSLTP+ +H R
Sbjct: 164 HYTHTWAVHIPNGDNNGKADVVAQEHGFVNLGKILDDHYLFVHHRVAKRSLTPSSKHQTR 223
Query: 506 LEGDSRVRWAEQQKILSRKKRDF 574
L+ D+RV WA+QQ R+KRDF
Sbjct: 224 LDEDTRVHWAQQQIAKPRRKRDF 246
Score = 52.4 bits (120), Expect = 1e-05
Identities = 20/23 (86%), Positives = 20/23 (86%)
Frame = +2
Query: 725 NDPKWPHMWYLNRGGGLXMNVIP 793
NDPKW HMWYLNRGG L MNVIP
Sbjct: 269 NDPKWEHMWYLNRGGDLDMNVIP 291
>UniRef50_P09958 Cluster: Furin precursor; n=55; Euteleostomi|Rep:
Furin precursor - Homo sapiens (Human)
Length = 794
Score = 101 bits (243), Expect = 2e-20
Identities = 45/79 (56%), Positives = 57/79 (72%)
Frame = +2
Query: 335 YTPTWAVHIPEGREVADAVARDHGFVNLGKIFDDHYHFHHRSLTKRSLTPAHEHHGRLEG 514
+T TWAV IP G VA++VAR HGF+NLG+IF D+YHF HR +TKRSL+P H RL+
Sbjct: 30 FTNTWAVRIPGGPAVANSVARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQR 89
Query: 515 DSRVRWAEQQKILSRKKRD 571
+ +V+W EQQ R KRD
Sbjct: 90 EPQVQWLEQQVAKRRTKRD 108
>UniRef50_P30432 Cluster: Furin-like protease 2 precursor; n=13;
Endopterygota|Rep: Furin-like protease 2 precursor -
Drosophila melanogaster (Fruit fly)
Length = 1679
Score = 91.5 bits (217), Expect = 2e-17
Identities = 57/164 (34%), Positives = 85/164 (51%), Gaps = 11/164 (6%)
Frame = +2
Query: 335 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTPAHEHHGRL 508
YT +AV+IP G+++AD +A HGF+N G+I D++Y F H ++KRSL + +H G L
Sbjct: 239 YTNEFAVNIPAGKQMADVIATKHGFINRGQIGSLDNYYLFQHHHVSKRSLRSSRKHQGAL 298
Query: 509 EGDSRVRWAEQQKILSRKKRD--FQIISTL--YSTAETR---TSEPXXXXXXXXXXXXXX 667
+ ++ V+W +QQ R+KRD +Q + T Y+ +P
Sbjct: 299 KSENEVKWMQQQHEKVRRKRDGPYQDLPTYSPYNLLRQHGGYVVDPNPHLSFSPESISLA 358
Query: 668 ELNTRIRGRTRSADLKFILNDPKWPHMWYLNRGG--GLXMNVIP 793
+ R+ R S+ FI DP + WYLN G GL MNV P
Sbjct: 359 SHSQRMEYRDVSS--HFIFPDPLFKEQWYLNGGAKDGLDMNVGP 400
>UniRef50_Q9Y1A6 Cluster: Furin1-X; n=8; Fungi/Metazoa group|Rep:
Furin1-X - Lymnaea stagnalis (Great pond snail)
Length = 967
Score = 89.4 bits (212), Expect = 9e-17
Identities = 43/86 (50%), Positives = 54/86 (62%), Gaps = 1/86 (1%)
Frame = +2
Query: 314 IETTLG-HYTPTWAVHIPEGREVADAVARDHGFVNLGKIFDDHYHFHHRSLTKRSLTPAH 490
+ET +G H+T WAVH+ G EVA AVA HGF+ G+I D+YHF HR + KRS +
Sbjct: 19 LETVVGKHFTDLWAVHVKGGEEVAKAVAVRHGFIYKGQIMPDYYHFQHRKVAKRSTFASI 78
Query: 491 EHHGRLEGDSRVRWAEQQKILSRKKR 568
+H L DS V W EQQ SR+KR
Sbjct: 79 HYHQPLAEDSDVLWVEQQVAKSRQKR 104
Score = 47.2 bits (107), Expect = 5e-04
Identities = 18/21 (85%), Positives = 18/21 (85%)
Frame = +2
Query: 725 NDPKWPHMWYLNRGGGLXMNV 787
NDPKWP MWYLNRG GL MNV
Sbjct: 109 NDPKWPLMWYLNRGSGLDMNV 129
>UniRef50_A3QQQ2 Cluster: Furin-2; n=3; Limulidae|Rep: Furin-2 -
Carcinoscorpius rotundicauda (Southeast Asian horseshoe
crab)
Length = 754
Score = 87.4 bits (207), Expect = 4e-16
Identities = 37/86 (43%), Positives = 52/86 (60%)
Frame = +2
Query: 332 HYTPTWAVHIPEGREVADAVARDHGFVNLGKIFDDHYHFHHRSLTKRSLTPAHEHHGRLE 511
HYT + VH+ G +VA +A HGFV LG+IFD+++H H ++KRS+ P+ HH L
Sbjct: 34 HYTDQFVVHVEGGPKVAKELAEKHGFVYLGEIFDNYHHLRHHQVSKRSIEPSLRHHEALH 93
Query: 512 GDSRVRWAEQQKILSRKKRDFQIIST 589
D +V+W QQ + R KRD T
Sbjct: 94 TDRQVKWFSQQTLKKRSKRDLSYFHT 119
Score = 45.6 bits (103), Expect = 0.001
Identities = 18/24 (75%), Positives = 18/24 (75%)
Frame = +2
Query: 722 LNDPKWPHMWYLNRGGGLXMNVIP 793
LNDPKW MWYLNRG L MNV P
Sbjct: 125 LNDPKWKDMWYLNRGNNLDMNVKP 148
>UniRef50_Q26489 Cluster: Endoprotease FURIN; n=5;
Endopterygota|Rep: Endoprotease FURIN - Spodoptera
frugiperda (Fall armyworm)
Length = 1299
Score = 84.6 bits (200), Expect = 3e-15
Identities = 56/157 (35%), Positives = 73/157 (46%), Gaps = 4/157 (2%)
Frame = +2
Query: 335 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTPAHEHHGRL 508
Y +AVH+P G D +AR HGFVN G+I ++Y H + KRS P+HEHH +L
Sbjct: 25 YHDQFAVHVPAGPHHVDDIARRHGFVNHGQIGSLKNYYLLSHHEVRKRSTEPSHEHHKKL 84
Query: 509 EGDSRVRWAEQQKILSRKKRDFQIISTLYSTAETRTSEPXXXXXXXXXXXXXXELNTRIR 688
+ +VRW EQQ+ R KRD+ + +R +P T R
Sbjct: 85 NDEPQVRWFEQQREKRRIKRDYSPYDRASFSQLSRRLQPH---------------RTNYR 129
Query: 689 GRTRSADLKFILNDPKWPHMWYLNRGG--GLXMNVIP 793
T S DP + WYLN G GL MNV P
Sbjct: 130 ALTSSP----FFPDPLFKEQWYLNGGAKDGLDMNVAP 162
>UniRef50_P29122 Cluster: Proprotein convertase subtilisin/kexin
type 6 precursor; n=40; Theria|Rep: Proprotein
convertase subtilisin/kexin type 6 precursor - Homo
sapiens (Human)
Length = 969
Score = 69.7 bits (163), Expect(2) = 6e-15
Identities = 34/80 (42%), Positives = 47/80 (58%), Gaps = 2/80 (2%)
Frame = +2
Query: 335 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTPAHEHHGRL 508
YT WAV + G AD VA HG++NLG+I +D+YHF+H KRS + H L
Sbjct: 70 YTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTLSSRGPHTFL 129
Query: 509 EGDSRVRWAEQQKILSRKKR 568
D +V+W +QQ++ R KR
Sbjct: 130 RMDPQVKWLQQQEVKRRVKR 149
Score = 33.9 bits (74), Expect(2) = 6e-15
Identities = 13/33 (39%), Positives = 19/33 (57%)
Frame = +2
Query: 668 ELNTRIRGRTRSADLKFILNDPKWPHMWYLNRG 766
E+ R++ + RS NDP W +MWYL+ G
Sbjct: 142 EVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCG 174
>UniRef50_Q17124 Cluster: Subtilisin-related protease SPC3; n=6;
Coelomata|Rep: Subtilisin-related protease SPC3 -
Branchiostoma californiensis (California lancelet)
(Amphioxus)
Length = 774
Score = 81.8 bits (193), Expect = 2e-14
Identities = 39/82 (47%), Positives = 51/82 (62%), Gaps = 2/82 (2%)
Frame = +2
Query: 329 GHYTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTPAHEHHG 502
GH+T TWAV I G + AD +A DHG+ NLG+I +DHY F H+ + RS AH+H
Sbjct: 29 GHFTNTWAVEIYGGPDRADLLALDHGYENLGQIGNLEDHYLFRHKDVPHRSRRGAHQHTK 88
Query: 503 RLEGDSRVRWAEQQKILSRKKR 568
RL D R++W QQ +R KR
Sbjct: 89 RLGDDERIQWVAQQVGRARSKR 110
>UniRef50_P29146 Cluster: PC3-like endoprotease variant A precursor;
n=5; Cnidaria|Rep: PC3-like endoprotease variant A
precursor - Hydra attenuata (Hydra) (Hydra vulgaris)
Length = 793
Score = 81.0 bits (191), Expect = 3e-14
Identities = 39/83 (46%), Positives = 52/83 (62%), Gaps = 3/83 (3%)
Frame = +2
Query: 332 HYTPTWAVHI-PEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTPAHEHHG 502
+++ TWAVHI P +VAD +A+ HGF N+GKI + HYHF H + +R L A
Sbjct: 71 YFSNTWAVHIDPPDNDVADRIAKKHGFTNIGKIGNIEGHYHFKHEEIGERELEKARHKTA 130
Query: 503 RLEGDSRVRWAEQQKILSRKKRD 571
L + V++AEQQKIL R KRD
Sbjct: 131 LLNLEDEVKFAEQQKILERVKRD 153
>UniRef50_Q26352 Cluster: Lfur2; n=3; Gastropoda|Rep: Lfur2 -
Lymnaea stagnalis (Great pond snail)
Length = 837
Score = 74.9 bits (176), Expect = 2e-12
Identities = 39/88 (44%), Positives = 54/88 (61%), Gaps = 2/88 (2%)
Frame = +2
Query: 317 ETTLGHYTPTWAVHIPEGREVADAVARDHGFVNLGKIFD--DHYHFHHRSLTKRSLTPAH 490
++T Y +AVHI GR VA+ VAR+ G N+G+I + D+Y F +RS +P+H
Sbjct: 28 KSTAEVYINQFAVHIEGGRHVANRVARETGLRNIGQIGNLADYYLFEAPQRERRSASPSH 87
Query: 491 EHHGRLEGDSRVRWAEQQKILSRKKRDF 574
+HH L S+V W EQQ SR+KRDF
Sbjct: 88 DHHAVLREHSQVNWFEQQVAKSRRKRDF 115
Score = 33.9 bits (74), Expect = 4.7
Identities = 14/25 (56%), Positives = 16/25 (64%), Gaps = 2/25 (8%)
Frame = +2
Query: 722 LNDPKWPHMWYLNRG--GGLXMNVI 790
+ DP W WYLNRG GG MNV+
Sbjct: 126 VTDPNWKDQWYLNRGAYGGNDMNVL 150
>UniRef50_Q9NJ15 Cluster: Proprotein convertase subtilisin/kexin
type 5 precursor; n=3; Branchiostoma californiense|Rep:
Proprotein convertase subtilisin/kexin type 5 precursor
- Branchiostoma californiensis (California lancelet)
(Amphioxus)
Length = 1696
Score = 74.5 bits (175), Expect = 3e-12
Identities = 35/89 (39%), Positives = 50/89 (56%), Gaps = 2/89 (2%)
Frame = +2
Query: 335 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTPAHEHHGRL 508
Y WA+H+ G AD +A HGF+N G+I +DHY F HR KRSL + H L
Sbjct: 31 YRNEWALHVEGGTAAADRLASKHGFINKGQIGSLEDHYLFVHRRTWKRSLRSSSHRHALL 90
Query: 509 EGDSRVRWAEQQKILSRKKRDFQIISTLY 595
+ + VRW +QQ + R KR + + ++Y
Sbjct: 91 QREPEVRWLQQQVVKRRVKRRVKRVYSMY 119
>UniRef50_UPI0000E47C72 Cluster: PREDICTED: similar to furin1-X;
n=3; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to furin1-X - Strongylocentrotus purpuratus
Length = 746
Score = 73.3 bits (172), Expect = 6e-12
Identities = 41/90 (45%), Positives = 50/90 (55%), Gaps = 3/90 (3%)
Frame = +2
Query: 329 GHYTPTWAVHIPEGREVADAVARDHGFVNLGKIFDDHYHF---HHRSLTKRSLTPAHEHH 499
G YT T+AVHI G A VA+ H FV LG+I DHYH HH KRS + + H
Sbjct: 28 GVYTNTYAVHIEGGPAEAAIVAKAHNFVYLGEILQDHYHLLDEHH--TVKRSTSHSQVRH 85
Query: 500 GRLEGDSRVRWAEQQKILSRKKRDFQIIST 589
G L + +V W EQQ SR+KRD + T
Sbjct: 86 GHLSEEPKVLWFEQQIARSRQKRDLVDLGT 115
Score = 42.3 bits (95), Expect = 0.013
Identities = 16/24 (66%), Positives = 20/24 (83%)
Frame = +2
Query: 722 LNDPKWPHMWYLNRGGGLXMNVIP 793
LNDPKWP +WYL RG G+ MN++P
Sbjct: 122 LNDPKWP-IWYLARGPGIDMNILP 144
>UniRef50_Q069L1 Cluster: Proprotein convertase subtilisin/kexin
type5a precursor; n=6; Coelomata|Rep: Proprotein
convertase subtilisin/kexin type5a precursor - Danio
rerio (Zebrafish) (Brachydanio rerio)
Length = 1093
Score = 70.9 bits (166), Expect = 3e-11
Identities = 33/80 (41%), Positives = 46/80 (57%), Gaps = 2/80 (2%)
Frame = +2
Query: 335 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTPAHEHHGRL 508
YT WAV I G E AD +A +GFVN+G+I DHY F H + KRS + +H +
Sbjct: 25 YTNRWAVKITGGPEAADLIAEKYGFVNMGQIGGLVDHYQFQHSGIIKRSTIKSKGNHSLI 84
Query: 509 EGDSRVRWAEQQKILSRKKR 568
+++V W +QQ + R KR
Sbjct: 85 TMETKVEWIQQQMVQKRVKR 104
>UniRef50_Q6UW60 Cluster: Proprotein convertase subtilisin/kexin
type 4 precursor; n=10; Tetrapoda|Rep: Proprotein
convertase subtilisin/kexin type 4 precursor - Homo
sapiens (Human)
Length = 755
Score = 70.9 bits (166), Expect = 3e-11
Identities = 32/80 (40%), Positives = 48/80 (60%), Gaps = 2/80 (2%)
Frame = +2
Query: 335 YTPTWAVHIPEGREVADAVARDHGFVNLGKIFDD--HYHFHHRSLTKRSLTPAHEHHGRL 508
Y +WAV + +G + +AR GFVNLG IF D ++H HR + ++SLTP H L
Sbjct: 34 YVSSWAVQVSQGNREVERLARKFGFVNLGPIFSDGQYFHLRHRGVVQQSLTPHWGHRLHL 93
Query: 509 EGDSRVRWAEQQKILSRKKR 568
+ + +V+W +QQ + R KR
Sbjct: 94 KKNPKVQWFQQQTLQRRVKR 113
>UniRef50_P41413 Cluster: Proprotein convertase subtilisin/kexin
type 5 precursor; n=1; Rattus norvegicus|Rep: Proprotein
convertase subtilisin/kexin type 5 precursor - Rattus
norvegicus (Rat)
Length = 1877
Score = 70.1 bits (164), Expect = 6e-11
Identities = 32/84 (38%), Positives = 48/84 (57%), Gaps = 2/84 (2%)
Frame = +2
Query: 335 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTPAHEHHGRL 508
YT WAV I G AD +A +GF+N+G+I D+YHF+H KRS+ + H +
Sbjct: 37 YTNHWAVKIAGGFAEADRIASKYGFINVGQIGALKDYYHFYHSRTIKRSVLSSRGTHSFI 96
Query: 509 EGDSRVRWAEQQKILSRKKRDFQI 580
+ +V W +QQ + R KRD+ +
Sbjct: 97 SMEPKVEWIQQQVVKKRTKRDYDL 120
>UniRef50_Q92824 Cluster: Proprotein convertase subtilisin/kexin
type 5 precursor; n=29; Eumetazoa|Rep: Proprotein
convertase subtilisin/kexin type 5 precursor - Homo
sapiens (Human)
Length = 913
Score = 67.7 bits (158), Expect = 3e-10
Identities = 31/82 (37%), Positives = 47/82 (57%), Gaps = 2/82 (2%)
Frame = +2
Query: 335 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTPAHEHHGRL 508
YT WAV I G A+ +A +GF+N+G+I D+YHF+H KRS+ + H +
Sbjct: 35 YTNHWAVKIAGGFPEANRIASKYGFINIGQIGALKDYYHFYHSRTIKRSVISSRGTHSFI 94
Query: 509 EGDSRVRWAEQQKILSRKKRDF 574
+ +V W +QQ + R KRD+
Sbjct: 95 SMEPKVEWIQQQVVKKRTKRDY 116
>UniRef50_Q5EE48 Cluster: Proprotein convertase 6B; n=22;
Coelomata|Rep: Proprotein convertase 6B - Xenopus laevis
(African clawed frog)
Length = 1849
Score = 67.3 bits (157), Expect = 4e-10
Identities = 30/87 (34%), Positives = 49/87 (56%), Gaps = 2/87 (2%)
Frame = +2
Query: 335 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTPAHEHHGRL 508
+T WAV I G A+ +A +G++N+G+I D+YHF H KRS+ + H +
Sbjct: 31 FTNHWAVRIAGGENEANRIASKYGYINIGRIGALQDYYHFFHSKTIKRSILASRGTHSFI 90
Query: 509 EGDSRVRWAEQQKILSRKKRDFQIIST 589
+ +V W +QQ + R KRD++ +T
Sbjct: 91 SMEPKVEWIQQQVVKRRIKRDYKPTNT 117
>UniRef50_Q069L0 Cluster: Proprotein convertase subtilisin/kexin
type5b precursor; n=6; Bilateria|Rep: Proprotein
convertase subtilisin/kexin type5b precursor - Danio
rerio (Zebrafish) (Brachydanio rerio)
Length = 917
Score = 66.5 bits (155), Expect = 7e-10
Identities = 33/83 (39%), Positives = 47/83 (56%), Gaps = 2/83 (2%)
Frame = +2
Query: 335 YTPTWAVHIPEGREVADAVARDHGFVNLGKIFD--DHYHFHHRSLTKRSLTPAHEHHGRL 508
YT WAV I G E A+ +A +G+ NLG+I D D+YHF H KRS + H +
Sbjct: 30 YTNHWAVRIAGGPEQAEHIANKYGYRNLGQIGDLKDYYHFFHSRTIKRSTLFSRGMHSFI 89
Query: 509 EGDSRVRWAEQQKILSRKKRDFQ 577
+ +V W +QQ + R KRD++
Sbjct: 90 SMEPKVEWVQQQVVKRRIKRDYK 112
>UniRef50_A7T2M8 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 349
Score = 64.9 bits (151), Expect = 2e-09
Identities = 33/81 (40%), Positives = 45/81 (55%), Gaps = 3/81 (3%)
Frame = +2
Query: 335 YTPTWAVHIPEGR-EVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTPAHEHHGR 505
+ +WAVH+ + + +A HGFVNLG+I +YHF RS R EH R
Sbjct: 34 FANSWAVHLDNADPDSVEKIATRHGFVNLGQIGSLPGYYHFVKRSTEMRRRRSLDEHADR 93
Query: 506 LEGDSRVRWAEQQKILSRKKR 568
L+ + +V W EQQ+IL R KR
Sbjct: 94 LQDEPQVTWVEQQRILERSKR 114
>UniRef50_A7SSI6 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 587
Score = 64.1 bits (149), Expect = 4e-09
Identities = 36/83 (43%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Frame = +2
Query: 335 YTPTWAVHIPEGR-EVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTPAHEHHGR 505
++ WAV + +ADA+AR HGF NLG I HY F H S R R
Sbjct: 1 FSNVWAVQLDSNDGSLADAIARAHGFKNLGGIGTLTGHYEFVHDSTGSRMRRSMESRTKR 60
Query: 506 LEGDSRVRWAEQQKILSRKKRDF 574
L RV WA+QQ+IL R+KRDF
Sbjct: 61 LISHPRVIWAKQQRILDRQKRDF 83
>UniRef50_P29120 Cluster: Neuroendocrine convertase 1 precursor;
n=27; Euteleostomi|Rep: Neuroendocrine convertase 1
precursor - Homo sapiens (Human)
Length = 753
Score = 60.5 bits (140), Expect = 5e-08
Identities = 33/76 (43%), Positives = 42/76 (55%), Gaps = 2/76 (2%)
Frame = +2
Query: 347 WAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTPAHEHHGRLEGDS 520
WA IP G E A A+A + G+ LG+I ++HY F H++ +RS A RL D
Sbjct: 35 WAAEIPGGPEAASAIAEELGYDLLGQIGSLENHYLFKHKNHPRRSRRSAFHITKRLSDDD 94
Query: 521 RVRWAEQQKILSRKKR 568
RV WAEQQ R KR
Sbjct: 95 RVIWAEQQYEKERSKR 110
>UniRef50_Q4SQ87 Cluster: Chromosome 4 SCAF14533, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 4 SCAF14533, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1780
Score = 54.4 bits (125), Expect = 3e-06
Identities = 32/97 (32%), Positives = 46/97 (47%), Gaps = 2/97 (2%)
Frame = +2
Query: 335 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTPAHEHHGRL 508
YT WA+ I EV +A HGF NLG+I +Y F HR KRS + +
Sbjct: 64 YTNDWALKITADEEVVGRIAEKHGFTNLGQIGHLKSYYSFRHRETAKRSDEANGDVTVGV 123
Query: 509 EGDSRVRWAEQQKILSRKKRDFQIISTLYSTAETRTS 619
++ V W +QQ I R +R +I + ++ TS
Sbjct: 124 AKETEVDWLQQQVIQRRAQRSPRISQVDSARTKSNTS 160
>UniRef50_Q4S7D2 Cluster: Chromosome 13 SCAF14715, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 13
SCAF14715, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 834
Score = 54.4 bits (125), Expect = 3e-06
Identities = 21/51 (41%), Positives = 34/51 (66%)
Frame = +2
Query: 419 GKIFDDHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKRD 571
G++F D+YHF H ++ KR+ + H +L+ + +V WA+QQ + RKKRD
Sbjct: 1 GQVFGDYYHFRHHAVEKRATSSHRGIHKKLQEEPKVLWAQQQVVKKRKKRD 51
>UniRef50_Q10575 Cluster: Prohormone convertase 2; n=5;
Chromadorea|Rep: Prohormone convertase 2 -
Caenorhabditis elegans
Length = 652
Score = 54.4 bits (125), Expect = 3e-06
Identities = 30/85 (35%), Positives = 45/85 (52%), Gaps = 4/85 (4%)
Frame = +2
Query: 335 YTPTWAVHIPEGREVADA--VARDHGFVNLGKIF--DDHYHFHHRSLTKRSLTPAHEHHG 502
YT + VH+ EG + DA +A+ HGF+N G++ D+ YHF +L + HH
Sbjct: 26 YTNHFHVHLKEGGGLEDAHRIAKRHGFINRGQVAASDNEYHFVQPALVHARTRRSAGHHA 85
Query: 503 RLEGDSRVRWAEQQKILSRKKRDFQ 577
+L D V EQ K +R KR ++
Sbjct: 86 KLHNDDEVLHVEQLKGYTRTKRGYR 110
>UniRef50_A7RME4 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 597
Score = 53.2 bits (122), Expect = 7e-06
Identities = 29/82 (35%), Positives = 41/82 (50%), Gaps = 2/82 (2%)
Frame = +2
Query: 335 YTPTWAVHIPEGREVADAVARDHGFVNL--GKIFDDHYHFHHRSLTKRSLTPAHEHHGRL 508
YT TW ++ +G+E D +A HGF + G + Y H+ +KR H
Sbjct: 28 YTNTWVIYTDKGQEYVDNLAAKHGFKSHRDGGGLEGFYILEHQRTSKRMRRSLVHHSTNF 87
Query: 509 EGDSRVRWAEQQKILSRKKRDF 574
D V +A+QQKIL R+KR F
Sbjct: 88 LRDPHVSYAKQQKILRRQKRGF 109
>UniRef50_Q16971 Cluster: PC1B protein; n=2; Aplysia
californica|Rep: PC1B protein - Aplysia californica
(California sea hare)
Length = 712
Score = 52.0 bits (119), Expect = 2e-05
Identities = 30/76 (39%), Positives = 36/76 (47%), Gaps = 2/76 (2%)
Frame = +2
Query: 347 WAVHIPEGREVADAVARDHGF--VNLGKIFDDHYHFHHRSLTKRSLTPAHEHHGRLEGDS 520
WAV I G A++VA HG+ V K DHY RS AH H +L D
Sbjct: 44 WAVQIQGGESHAESVAAQHGYTLVRALKSIPDHYVLRRSDTPHRSRRSAHHHTRKLSEDE 103
Query: 521 RVRWAEQQKILSRKKR 568
RV + EQQ+ R KR
Sbjct: 104 RVAFVEQQQQKRRVKR 119
>UniRef50_Q4SII7 Cluster: Chromosome 5 SCAF14581, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 5 SCAF14581, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 57
Score = 51.6 bits (118), Expect = 2e-05
Identities = 20/31 (64%), Positives = 24/31 (77%)
Frame = +2
Query: 335 YTPTWAVHIPEGREVADAVARDHGFVNLGKI 427
YT TWAVH+P G+EVAD VA HGF+N G +
Sbjct: 5 YTNTWAVHVPGGQEVADRVANKHGFINYGHV 35
>UniRef50_P16519 Cluster: Neuroendocrine convertase 2 precursor;
n=26; Deuterostomia|Rep: Neuroendocrine convertase 2
precursor - Homo sapiens (Human)
Length = 638
Score = 49.2 bits (112), Expect(2) = 3e-05
Identities = 28/76 (36%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Frame = +2
Query: 368 GREVADAVARDHGF-VNLGKIFDDHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQ 544
G + A VA +HGF V + YHF+H L K + H +LE D RV+ A QQ
Sbjct: 42 GEDKARQVAAEHGFGVRKLPFAEGLYHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQ 101
Query: 545 KILSRKKRDFQIISTL 592
+ RKKR ++ I+ +
Sbjct: 102 EGFDRKKRGYRDINEI 117
Score = 21.4 bits (43), Expect(2) = 3e-05
Identities = 9/28 (32%), Positives = 13/28 (46%)
Frame = +2
Query: 686 RGRTRSADLKFILNDPKWPHMWYLNRGG 769
RG ++ +NDP + WYL G
Sbjct: 109 RGYRDINEIDINMNDPLFTKQWYLINTG 136
>UniRef50_Q17325 Cluster: CelfurPC protein; n=4; Chromadorea|Rep:
CelfurPC protein - Caenorhabditis elegans
Length = 692
Score = 49.6 bits (113), Expect = 9e-05
Identities = 45/148 (30%), Positives = 62/148 (41%), Gaps = 4/148 (2%)
Frame = +2
Query: 335 YTPTWAVHIPEGR-EVADAVARDHGFVNLGKIF--DDHYHFHH-RSLTKRSLTPAHEHHG 502
YT WAV I G+ E A+ +A +G+ NLG I D++Y F R ++ S
Sbjct: 58 YTNEWAVRIAGGKVEEANRLANKYGYTNLGPIIPGDEYYLFRDDRKKSRSSRKTRSLSAN 117
Query: 503 RLEGDSRVRWAEQQKILSRKKRDFQIISTLYSTAETRTSEPXXXXXXXXXXXXXXELNTR 682
+L+ + V W EQQ R KR ++ I T + E ++
Sbjct: 118 QLQHEEDVMWMEQQVAKRRVKRGYRRIRR--HTDDNDIFEEDDDGTQI----------SK 165
Query: 683 IRGRTRSADLKFILNDPKWPHMWYLNRG 766
R R NDP W MWYLNRG
Sbjct: 166 SRNRKHPDP-----NDPLWTDMWYLNRG 188
>UniRef50_O17798 Cluster: Putative uncharacterized protein kpc-1;
n=1; Caenorhabditis elegans|Rep: Putative
uncharacterized protein kpc-1 - Caenorhabditis elegans
Length = 760
Score = 49.6 bits (113), Expect = 9e-05
Identities = 45/148 (30%), Positives = 62/148 (41%), Gaps = 4/148 (2%)
Frame = +2
Query: 335 YTPTWAVHIPEGR-EVADAVARDHGFVNLGKIF--DDHYHFHH-RSLTKRSLTPAHEHHG 502
YT WAV I G+ E A+ +A +G+ NLG I D++Y F R ++ S
Sbjct: 58 YTNEWAVRIAGGKVEEANRLANKYGYTNLGPIIPGDEYYLFRDDRKKSRSSRKTRSLSAN 117
Query: 503 RLEGDSRVRWAEQQKILSRKKRDFQIISTLYSTAETRTSEPXXXXXXXXXXXXXXELNTR 682
+L+ + V W EQQ R KR ++ I T + E ++
Sbjct: 118 QLQHEEDVMWMEQQVAKRRVKRGYRRIRR--HTDDNDIFEEDDDGTQI----------SK 165
Query: 683 IRGRTRSADLKFILNDPKWPHMWYLNRG 766
R R NDP W MWYLNRG
Sbjct: 166 SRNRKHPDP-----NDPLWTDMWYLNRG 188
>UniRef50_UPI0000DB7713 Cluster: PREDICTED: similar to proprotein
convertase subtilisin/kexin type 1 preproprotein isoform
1; n=2; Apocrita|Rep: PREDICTED: similar to proprotein
convertase subtilisin/kexin type 1 preproprotein isoform
1 - Apis mellifera
Length = 714
Score = 48.4 bits (110), Expect = 2e-04
Identities = 35/145 (24%), Positives = 55/145 (37%), Gaps = 2/145 (1%)
Frame = +2
Query: 329 GHYTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTPAHEHHG 502
G W V I G VA +A G+ +LG + F D Y + + +
Sbjct: 37 GRREEEWVVRIEGGSPVASLLALQTGYKHLGPVLGFKDTYIWLKDDDSGQQKRGGFRSTK 96
Query: 503 RLEGDSRVRWAEQQKILSRKKRDFQIISTLYSTAETRTSEPXXXXXXXXXXXXXXELNTR 682
L S++ WA+QQK + R KRD+ +S+L S + + + +
Sbjct: 97 ALNSSSKIIWADQQKTIKRHKRDYVPLSSLDSEKPLIREKRLEVDQYRLNSIKEDDEDWQ 156
Query: 683 IRGRTRSADLKFILNDPKWPHMWYL 757
D + + ND W WYL
Sbjct: 157 EFRMEDPEDSRLMFNDELWDQEWYL 181
>UniRef50_UPI0000DB7774 Cluster: PREDICTED: similar to Furin-like
protease 1, isoforms 1/1-X/2 precursor (Furin-1)
(Kex2-like endoprotease 1) (dKLIP-1); n=1; Apis
mellifera|Rep: PREDICTED: similar to Furin-like protease
1, isoforms 1/1-X/2 precursor (Furin-1) (Kex2-like
endoprotease 1) (dKLIP-1) - Apis mellifera
Length = 1025
Score = 47.2 bits (107), Expect = 5e-04
Identities = 18/28 (64%), Positives = 22/28 (78%)
Frame = +2
Query: 704 ADLKFILNDPKWPHMWYLNRGGGLXMNV 787
++L+ +LND WP MWYLNRG GL MNV
Sbjct: 50 SNLRTVLNDEMWPQMWYLNRGKGLDMNV 77
Score = 42.7 bits (96), Expect = 0.010
Identities = 23/43 (53%), Positives = 26/43 (60%)
Frame = +2
Query: 452 HRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKRDFQI 580
H S+ KRS P GRL D RVR AEQQ++ SR KRD I
Sbjct: 3 HTSVVKRSAEPHFGVQGRLIEDRRVRRAEQQRVKSRTKRDLII 45
>UniRef50_Q9TTF8 Cluster: Furin; n=1; Ateles belzebuth chamek|Rep:
Furin - Ateles belzebuth chamek (Chamek spider monkey)
Length = 44
Score = 46.4 bits (105), Expect = 8e-04
Identities = 22/35 (62%), Positives = 26/35 (74%), Gaps = 2/35 (5%)
Frame = +2
Query: 329 GH--YTPTWAVHIPEGREVADAVARDHGFVNLGKI 427
GH +T TWAV IP G VA+ VAR HGF+NLG+I
Sbjct: 10 GHKVFTNTWAVRIPGGPVVANXVARKHGFLNLGQI 44
>UniRef50_UPI0000ECC1D3 Cluster: Proprotein convertase PC6; n=2;
Gallus gallus|Rep: Proprotein convertase PC6 - Gallus
gallus
Length = 1660
Score = 44.0 bits (99), Expect = 0.004
Identities = 17/48 (35%), Positives = 28/48 (58%)
Frame = +2
Query: 434 DHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKRDFQ 577
D+YHF+H KRS+ + H + + +V W +QQ + R KRD++
Sbjct: 7 DYYHFYHSKTIKRSVLSSRGTHSFISMEPKVEWIQQQVVKRRIKRDYK 54
>UniRef50_Q4S7D1 Cluster: Chromosome 13 SCAF14715, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 13
SCAF14715, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 86
Score = 42.7 bits (96), Expect = 0.010
Identities = 18/31 (58%), Positives = 21/31 (67%)
Frame = +2
Query: 335 YTPTWAVHIPEGREVADAVARDHGFVNLGKI 427
YT TWAV I G E AD +A HGF+N GK+
Sbjct: 42 YTNTWAVQIDGGPEEADRIAGQHGFINHGKV 72
>UniRef50_P51559 Cluster: Endoprotease bli-4 precursor; n=13;
Chromadorea|Rep: Endoprotease bli-4 precursor -
Caenorhabditis elegans
Length = 943
Score = 42.3 bits (95), Expect = 0.013
Identities = 37/140 (26%), Positives = 55/140 (39%), Gaps = 2/140 (1%)
Frame = +2
Query: 374 EVADAVARDHGFVNLGKIFDDHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKIL 553
E+A +A DH G F D ++F + S T R+ RL+ V W E+Q+
Sbjct: 52 ELARRIAADHDMHVKGDPFLDTHYFLYHSETTRTRRHKRAIVERLDSHPAVEWVEEQRPK 111
Query: 554 SRKKRDFQIISTLYSTAETRTSEPXXXXXXXXXXXXXXELNTRIRGRTRSADLKFILNDP 733
R KRD+ ++ + S P + + + L F DP
Sbjct: 112 KRVKRDYILLDN-----DVHHSNPFRRSVLNRDGTRRAQ-RQQPQSPAEIPSLPF--PDP 163
Query: 734 KWPHMWYLNRG--GGLXMNV 787
+ WYL+ G GG MNV
Sbjct: 164 LYKDQWYLHGGAVGGYDMNV 183
>UniRef50_UPI0000E24E64 Cluster: PREDICTED: similar to proprotein
convertase subtilisin/kexin type 4; n=1; Pan
troglodytes|Rep: PREDICTED: similar to proprotein
convertase subtilisin/kexin type 4 - Pan troglodytes
Length = 592
Score = 41.1 bits (92), Expect = 0.031
Identities = 20/51 (39%), Positives = 31/51 (60%), Gaps = 2/51 (3%)
Frame = +2
Query: 422 KIFDDHYHFH--HRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKR 568
+IF D +FH HR + ++SLTP H L+ + +V+W +QQ + R KR
Sbjct: 124 QIFPDGQYFHLRHRGVVQQSLTPHWGHRLHLKKNPKVQWFQQQTLQRRVKR 174
>UniRef50_UPI00005884A1 Cluster: PREDICTED: similar to GA10554-PA;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to GA10554-PA - Strongylocentrotus purpuratus
Length = 523
Score = 41.1 bits (92), Expect = 0.031
Identities = 18/47 (38%), Positives = 25/47 (53%)
Frame = +2
Query: 431 DDHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKRD 571
+DHY F H+ + KRS + H + + V W EQQ + R KRD
Sbjct: 12 EDHYMFSHQKVFKRSTMASTGAHTNIADEPEVEWFEQQVLRKRVKRD 58
>UniRef50_UPI0000EB1075 Cluster: Furin precursor (EC 3.4.21.75)
(Paired basic amino acid residue cleaving enzyme) (PACE)
(Dibasic-processing enzyme).; n=1; Canis lupus
familiaris|Rep: Furin precursor (EC 3.4.21.75) (Paired
basic amino acid residue cleaving enzyme) (PACE)
(Dibasic-processing enzyme). - Canis familiaris
Length = 679
Score = 40.7 bits (91), Expect = 0.041
Identities = 24/69 (34%), Positives = 36/69 (52%)
Frame = +2
Query: 365 EGREVADAVARDHGFVNLGKIFDDHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQ 544
+G AD++A +GF L +IF +TK+SL P H H RL + +++W EQ
Sbjct: 29 QGPAAADSLAHKNGFFILCQIFTT-ITTSGTEVTKQSLLPHHLEHRRLWREPQLQWLEQL 87
Query: 545 KILSRKKRD 571
R +RD
Sbjct: 88 VAKQRTQRD 96
>UniRef50_UPI0000E48CE0 Cluster: PREDICTED: similar to
subtilisin-related protease SPC3, partial; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
subtilisin-related protease SPC3, partial -
Strongylocentrotus purpuratus
Length = 80
Score = 37.5 bits (83), Expect = 0.38
Identities = 17/45 (37%), Positives = 26/45 (57%)
Frame = +2
Query: 434 DHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKR 568
D Y F + ++ RS A+ ++ L D+RV W EQQKI+ K+
Sbjct: 6 DTYGFSKKKMSARSRRGANNYNKLLAEDTRVSWVEQQKIILHSKK 50
>UniRef50_Q967D4 Cluster: Multiadhesive protein; n=1; Geodia
cydonium|Rep: Multiadhesive protein - Geodia cydonium
(Sponge)
Length = 701
Score = 36.3 bits (80), Expect = 0.88
Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 7/80 (8%)
Frame = +2
Query: 335 YTPTWAVHIPEGREVADAVARDHGFVNLGKIFDDHYHFHHRSLTKRS---LTPAHE---- 493
Y W V IP GR+ AD VA GF N + D +R + K L P +E
Sbjct: 64 YATEWIVSIPGGRDAADEVAERLGFTNERMVSKDE-QILYRFVVKEEEAMLVPLNEPDRN 122
Query: 494 HHGRLEGDSRVRWAEQQKIL 553
G L + V++AEQ+ ++
Sbjct: 123 KTGHLLAEKDVQFAEQETVV 142
>UniRef50_A0ND65 Cluster: ENSANGP00000030184; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000030184 - Anopheles gambiae
str. PEST
Length = 59
Score = 36.3 bits (80), Expect = 0.88
Identities = 14/30 (46%), Positives = 22/30 (73%)
Frame = +2
Query: 335 YTPTWAVHIPEGREVADAVARDHGFVNLGK 424
Y +AV+IP G +VAD++A +GF N+G+
Sbjct: 30 YMNEFAVYIPRGADVADSIAHKYGFSNMGQ 59
>UniRef50_Q16549 Cluster: Proprotein convertase subtilisin/kexin
type 7 precursor; n=36; Eumetazoa|Rep: Proprotein
convertase subtilisin/kexin type 7 precursor - Homo
sapiens (Human)
Length = 785
Score = 35.9 bits (79), Expect = 1.2
Identities = 30/89 (33%), Positives = 43/89 (48%), Gaps = 14/89 (15%)
Frame = +2
Query: 344 TWAVHIP----EGREV-----ADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSL--TP 484
+WAVH+ +G E ADA+A+ G VN G+I HY F + + +L P
Sbjct: 53 SWAVHLESLEGDGEEETLEQQADALAQAAGLVNAGRIGELQGHYLFVQPAGHRPALEVEP 112
Query: 485 AHEH-HGRLEGDSRVRWAEQQKILSRKKR 568
+ L G VRW +Q++L R KR
Sbjct: 113 IRQQVEAVLAGHEAVRWHSEQRLLRRAKR 141
>UniRef50_Q9VBC7 Cluster: CG6438-PA; n=44; Coelomata|Rep: CG6438-PA
- Drosophila melanogaster (Fruit fly)
Length = 654
Score = 35.1 bits (77), Expect = 2.0
Identities = 28/83 (33%), Positives = 36/83 (43%), Gaps = 5/83 (6%)
Frame = +2
Query: 335 YTPTWAVHIPEG--REVADAVARDHGFVNLGKIF--DDH-YHFHHRSLTKRSLTPAHEHH 499
+T ++ V G A VA +GF NLG + D H YHF HR+L + H
Sbjct: 40 FTSSFLVRFRRGVDNSFAHDVADKYGFDNLGPLVGADGHEYHFKHRTLPHARSRRSLTHT 99
Query: 500 GRLEGDSRVRWAEQQKILSRKKR 568
L+ V A QQ R KR
Sbjct: 100 RALKSHPAVHTAVQQPGFKRVKR 122
>UniRef50_Q8I4G1 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 547
Score = 34.3 bits (75), Expect = 3.6
Identities = 15/46 (32%), Positives = 23/46 (50%)
Frame = +2
Query: 431 DDHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKR 568
+ H+H HH R L+ +H + G S++R L+RKKR
Sbjct: 34 NSHHHHHHLPPAPRHLSSSHHQIETISGSSKLRAQSGSPALNRKKR 79
>UniRef50_Q3SLV0 Cluster: Putative diguanylate
cyclase/phosphodiesterase; n=1; Thiobacillus
denitrificans ATCC 25259|Rep: Putative diguanylate
cyclase/phosphodiesterase - Thiobacillus denitrificans
(strain ATCC 25259)
Length = 606
Score = 33.1 bits (72), Expect = 8.2
Identities = 17/42 (40%), Positives = 22/42 (52%), Gaps = 2/42 (4%)
Frame = +2
Query: 401 HGFVNL--GKIFDDHYHFHHRSLTKRSLTPAHEHHGRLEGDS 520
HG V L G +F D HFHH R+ + A R+EG+S
Sbjct: 539 HGLVTLSIGAVFVDPTHFHHHQEVARAASDAKRMAKRVEGNS 580
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 775,752,010
Number of Sequences: 1657284
Number of extensions: 15610712
Number of successful extensions: 41022
Number of sequences better than 10.0: 49
Number of HSP's better than 10.0 without gapping: 39244
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 40925
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 67496806780
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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