Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P07_F_B11
(793 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X17094-1|CAA34948.1| 794|Homo sapiens protein ( Human fur mRNA ... 101 2e-21
X15723-1|CAA33745.1| 280|Homo sapiens furin protein. 101 2e-21
BC012181-1|AAH12181.1| 794|Homo sapiens furin (paired basic ami... 101 2e-21
D87993-1|BAA21791.1| 975|Homo sapiens PACE4E-I protein. 70 9e-16
AB001914-4|BAA21627.1| 975|Homo sapiens PACE4E-I protein. 70 9e-16
M80482-1|AAA59998.1| 969|Homo sapiens subtilisin-like protease ... 70 9e-16
AB001914-1|BAA21624.1| 969|Homo sapiens PACE4A-I protein. 70 9e-16
D87994-1|BAA21792.1| 962|Homo sapiens PACE4E-II protein. 70 9e-16
AB001914-3|BAA21626.1| 962|Homo sapiens PACE4E-II protein. 70 9e-16
D87995-1|BAA21793.1| 956|Homo sapiens PACE4A-II protein. 70 9e-16
AB001914-2|BAA21625.1| 956|Homo sapiens PACE4A-II protein. 70 9e-16
D28513-1|BAA05871.1| 652|Homo sapiens kexin-like protease protein. 70 9e-16
AB001914-5|BAA21621.1| 652|Homo sapiens PACE4C protein. 70 9e-16
AB001914-6|BAA21623.1| 623|Homo sapiens PACE4CS protein. 70 9e-16
AB001914-7|BAA21620.1| 487|Homo sapiens PACE4B protein. 70 9e-16
AM491522-1|CAM33226.1| 357|Homo sapiens proprotein convertase s... 60 9e-13
AY358963-1|AAQ89322.1| 755|Homo sapiens prohormone convertase p... 71 5e-12
U56387-1|AAC50643.2| 913|Homo sapiens protease PC6 isoform A pr... 68 4e-11
U49114-1|AAA91807.1| 899|Homo sapiens prohormone convertase 5 p... 68 4e-11
BC012064-1|AAH12064.1| 913|Homo sapiens proprotein convertase s... 68 4e-11
AL359253-2|CAH73743.1| 913|Homo sapiens proprotein convertase s... 68 4e-11
AL359253-1|CAH73742.1| 690|Homo sapiens proprotein convertase s... 68 4e-11
AL353607-2|CAI41233.1| 913|Homo sapiens proprotein convertase s... 68 4e-11
AL353607-1|CAI41232.1| 690|Homo sapiens proprotein convertase s... 68 4e-11
AB208955-1|BAD92192.1| 800|Homo sapiens paired basic amino acid... 46 7e-09
X64810-1|CAA46031.1| 753|Homo sapiens PC1/PC3 protein. 60 7e-09
M90753-1|AAA59918.1| 753|Homo sapiens PC1 protein. 60 7e-09
D73407-1|BAA11133.1| 753|Homo sapiens prohormone convertase 3 p... 60 7e-09
BC130295-1|AAI30296.1| 753|Homo sapiens proprotein convertase s... 60 7e-09
AB208874-1|BAD92111.1| 724|Homo sapiens proprotein convertase s... 60 7e-09
M95971-1|AAA59919.1| 638|Homo sapiens neuroendocrine convertase... 49 5e-06
J05252-1|AAA60032.1| 638|Homo sapiens endoprotease protein. 49 5e-06
BC005815-1|AAH05815.1| 638|Homo sapiens proprotein convertase s... 49 5e-06
AL359511-2|CAI20085.1| 638|Homo sapiens proprotein convertase s... 49 5e-06
AL121779-1|CAI19155.1| 638|Homo sapiens proprotein convertase s... 49 5e-06
AL031675-1|CAI22648.1| 638|Homo sapiens proprotein convertase s... 49 5e-06
AL031664-2|CAI21690.1| 638|Homo sapiens proprotein convertase s... 49 5e-06
BC040546-1|AAH40546.1| 619|Homo sapiens PCSK2 protein protein. 49 5e-06
AL359511-3|CAC34957.2| 619|Homo sapiens proprotein convertase s... 49 5e-06
AL121779-2|CAB96732.2| 619|Homo sapiens proprotein convertase s... 49 5e-06
AL031675-2|CAA21069.2| 619|Homo sapiens proprotein convertase s... 49 5e-06
AL031664-3|CAB89428.2| 619|Homo sapiens proprotein convertase s... 49 5e-06
BT006870-1|AAP35516.1| 785|Homo sapiens proprotein convertase s... 39 0.024
BC010696-1|AAH10696.1| 785|Homo sapiens proprotein convertase s... 39 0.024
BC006357-1|AAH06357.1| 591|Homo sapiens PCSK7 protein protein. 39 0.024
AK222907-1|BAD96627.1| 785|Homo sapiens proprotein convertase s... 39 0.024
U40623-1|AAC50417.1| 785|Homo sapiens PC8 precursor protein. 36 0.17
U33849-1|AAB03087.1| 785|Homo sapiens lymphoma proprotein conve... 36 0.17
>X17094-1|CAA34948.1| 794|Homo sapiens protein ( Human fur mRNA for
furin. ).
Length = 794
Score = 101 bits (243), Expect = 2e-21
Identities = 45/79 (56%), Positives = 57/79 (72%)
Frame = +2
Query: 335 YTPTWAVHIPEGREVADAVARDHGFVNLGKIFDDHYHFHHRSLTKRSLTPAHEHHGRLEG 514
+T TWAV IP G VA++VAR HGF+NLG+IF D+YHF HR +TKRSL+P H RL+
Sbjct: 30 FTNTWAVRIPGGPAVANSVARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQR 89
Query: 515 DSRVRWAEQQKILSRKKRD 571
+ +V+W EQQ R KRD
Sbjct: 90 EPQVQWLEQQVAKRRTKRD 108
>X15723-1|CAA33745.1| 280|Homo sapiens furin protein.
Length = 280
Score = 101 bits (243), Expect = 2e-21
Identities = 45/79 (56%), Positives = 57/79 (72%)
Frame = +2
Query: 335 YTPTWAVHIPEGREVADAVARDHGFVNLGKIFDDHYHFHHRSLTKRSLTPAHEHHGRLEG 514
+T TWAV IP G VA++VAR HGF+NLG+IF D+YHF HR +TKRSL+P H RL+
Sbjct: 30 FTNTWAVRIPGGPAVANSVARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQR 89
Query: 515 DSRVRWAEQQKILSRKKRD 571
+ +V+W EQQ R KRD
Sbjct: 90 EPQVQWLEQQVAKRRTKRD 108
>BC012181-1|AAH12181.1| 794|Homo sapiens furin (paired basic amino
acid cleaving enzyme) protein.
Length = 794
Score = 101 bits (243), Expect = 2e-21
Identities = 45/79 (56%), Positives = 57/79 (72%)
Frame = +2
Query: 335 YTPTWAVHIPEGREVADAVARDHGFVNLGKIFDDHYHFHHRSLTKRSLTPAHEHHGRLEG 514
+T TWAV IP G VA++VAR HGF+NLG+IF D+YHF HR +TKRSL+P H RL+
Sbjct: 30 FTNTWAVRIPGGPAVANSVARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQR 89
Query: 515 DSRVRWAEQQKILSRKKRD 571
+ +V+W EQQ R KRD
Sbjct: 90 EPQVQWLEQQVAKRRTKRD 108
>D87993-1|BAA21791.1| 975|Homo sapiens PACE4E-I protein.
Length = 975
Score = 69.7 bits (163), Expect(2) = 9e-16
Identities = 34/80 (42%), Positives = 47/80 (58%), Gaps = 2/80 (2%)
Frame = +2
Query: 335 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTPAHEHHGRL 508
YT WAV + G AD VA HG++NLG+I +D+YHF+H KRS + H L
Sbjct: 70 YTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTLSSRGPHTFL 129
Query: 509 EGDSRVRWAEQQKILSRKKR 568
D +V+W +QQ++ R KR
Sbjct: 130 RMDPQVKWLQQQEVKRRVKR 149
Score = 33.9 bits (74), Expect(2) = 9e-16
Identities = 13/33 (39%), Positives = 19/33 (57%)
Frame = +2
Query: 668 ELNTRIRGRTRSADLKFILNDPKWPHMWYLNRG 766
E+ R++ + RS NDP W +MWYL+ G
Sbjct: 142 EVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCG 174
>AB001914-4|BAA21627.1| 975|Homo sapiens PACE4E-I protein.
Length = 975
Score = 69.7 bits (163), Expect(2) = 9e-16
Identities = 34/80 (42%), Positives = 47/80 (58%), Gaps = 2/80 (2%)
Frame = +2
Query: 335 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTPAHEHHGRL 508
YT WAV + G AD VA HG++NLG+I +D+YHF+H KRS + H L
Sbjct: 70 YTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTLSSRGPHTFL 129
Query: 509 EGDSRVRWAEQQKILSRKKR 568
D +V+W +QQ++ R KR
Sbjct: 130 RMDPQVKWLQQQEVKRRVKR 149
Score = 33.9 bits (74), Expect(2) = 9e-16
Identities = 13/33 (39%), Positives = 19/33 (57%)
Frame = +2
Query: 668 ELNTRIRGRTRSADLKFILNDPKWPHMWYLNRG 766
E+ R++ + RS NDP W +MWYL+ G
Sbjct: 142 EVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCG 174
>M80482-1|AAA59998.1| 969|Homo sapiens subtilisin-like protease
protein.
Length = 969
Score = 69.7 bits (163), Expect(2) = 9e-16
Identities = 34/80 (42%), Positives = 47/80 (58%), Gaps = 2/80 (2%)
Frame = +2
Query: 335 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTPAHEHHGRL 508
YT WAV + G AD VA HG++NLG+I +D+YHF+H KRS + H L
Sbjct: 70 YTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTLSSRGPHTFL 129
Query: 509 EGDSRVRWAEQQKILSRKKR 568
D +V+W +QQ++ R KR
Sbjct: 130 RMDPQVKWLQQQEVKRRVKR 149
Score = 33.9 bits (74), Expect(2) = 9e-16
Identities = 13/33 (39%), Positives = 19/33 (57%)
Frame = +2
Query: 668 ELNTRIRGRTRSADLKFILNDPKWPHMWYLNRG 766
E+ R++ + RS NDP W +MWYL+ G
Sbjct: 142 EVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCG 174
>AB001914-1|BAA21624.1| 969|Homo sapiens PACE4A-I protein.
Length = 969
Score = 69.7 bits (163), Expect(2) = 9e-16
Identities = 34/80 (42%), Positives = 47/80 (58%), Gaps = 2/80 (2%)
Frame = +2
Query: 335 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTPAHEHHGRL 508
YT WAV + G AD VA HG++NLG+I +D+YHF+H KRS + H L
Sbjct: 70 YTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTLSSRGPHTFL 129
Query: 509 EGDSRVRWAEQQKILSRKKR 568
D +V+W +QQ++ R KR
Sbjct: 130 RMDPQVKWLQQQEVKRRVKR 149
Score = 33.9 bits (74), Expect(2) = 9e-16
Identities = 13/33 (39%), Positives = 19/33 (57%)
Frame = +2
Query: 668 ELNTRIRGRTRSADLKFILNDPKWPHMWYLNRG 766
E+ R++ + RS NDP W +MWYL+ G
Sbjct: 142 EVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCG 174
>D87994-1|BAA21792.1| 962|Homo sapiens PACE4E-II protein.
Length = 962
Score = 69.7 bits (163), Expect(2) = 9e-16
Identities = 34/80 (42%), Positives = 47/80 (58%), Gaps = 2/80 (2%)
Frame = +2
Query: 335 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTPAHEHHGRL 508
YT WAV + G AD VA HG++NLG+I +D+YHF+H KRS + H L
Sbjct: 70 YTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTLSSRGPHTFL 129
Query: 509 EGDSRVRWAEQQKILSRKKR 568
D +V+W +QQ++ R KR
Sbjct: 130 RMDPQVKWLQQQEVKRRVKR 149
Score = 33.9 bits (74), Expect(2) = 9e-16
Identities = 13/33 (39%), Positives = 19/33 (57%)
Frame = +2
Query: 668 ELNTRIRGRTRSADLKFILNDPKWPHMWYLNRG 766
E+ R++ + RS NDP W +MWYL+ G
Sbjct: 142 EVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCG 174
>AB001914-3|BAA21626.1| 962|Homo sapiens PACE4E-II protein.
Length = 962
Score = 69.7 bits (163), Expect(2) = 9e-16
Identities = 34/80 (42%), Positives = 47/80 (58%), Gaps = 2/80 (2%)
Frame = +2
Query: 335 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTPAHEHHGRL 508
YT WAV + G AD VA HG++NLG+I +D+YHF+H KRS + H L
Sbjct: 70 YTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTLSSRGPHTFL 129
Query: 509 EGDSRVRWAEQQKILSRKKR 568
D +V+W +QQ++ R KR
Sbjct: 130 RMDPQVKWLQQQEVKRRVKR 149
Score = 33.9 bits (74), Expect(2) = 9e-16
Identities = 13/33 (39%), Positives = 19/33 (57%)
Frame = +2
Query: 668 ELNTRIRGRTRSADLKFILNDPKWPHMWYLNRG 766
E+ R++ + RS NDP W +MWYL+ G
Sbjct: 142 EVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCG 174
>D87995-1|BAA21793.1| 956|Homo sapiens PACE4A-II protein.
Length = 956
Score = 69.7 bits (163), Expect(2) = 9e-16
Identities = 34/80 (42%), Positives = 47/80 (58%), Gaps = 2/80 (2%)
Frame = +2
Query: 335 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTPAHEHHGRL 508
YT WAV + G AD VA HG++NLG+I +D+YHF+H KRS + H L
Sbjct: 70 YTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTLSSRGPHTFL 129
Query: 509 EGDSRVRWAEQQKILSRKKR 568
D +V+W +QQ++ R KR
Sbjct: 130 RMDPQVKWLQQQEVKRRVKR 149
Score = 33.9 bits (74), Expect(2) = 9e-16
Identities = 13/33 (39%), Positives = 19/33 (57%)
Frame = +2
Query: 668 ELNTRIRGRTRSADLKFILNDPKWPHMWYLNRG 766
E+ R++ + RS NDP W +MWYL+ G
Sbjct: 142 EVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCG 174
>AB001914-2|BAA21625.1| 956|Homo sapiens PACE4A-II protein.
Length = 956
Score = 69.7 bits (163), Expect(2) = 9e-16
Identities = 34/80 (42%), Positives = 47/80 (58%), Gaps = 2/80 (2%)
Frame = +2
Query: 335 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTPAHEHHGRL 508
YT WAV + G AD VA HG++NLG+I +D+YHF+H KRS + H L
Sbjct: 70 YTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTLSSRGPHTFL 129
Query: 509 EGDSRVRWAEQQKILSRKKR 568
D +V+W +QQ++ R KR
Sbjct: 130 RMDPQVKWLQQQEVKRRVKR 149
Score = 33.9 bits (74), Expect(2) = 9e-16
Identities = 13/33 (39%), Positives = 19/33 (57%)
Frame = +2
Query: 668 ELNTRIRGRTRSADLKFILNDPKWPHMWYLNRG 766
E+ R++ + RS NDP W +MWYL+ G
Sbjct: 142 EVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCG 174
>D28513-1|BAA05871.1| 652|Homo sapiens kexin-like protease protein.
Length = 652
Score = 69.7 bits (163), Expect(2) = 9e-16
Identities = 34/80 (42%), Positives = 47/80 (58%), Gaps = 2/80 (2%)
Frame = +2
Query: 335 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTPAHEHHGRL 508
YT WAV + G AD VA HG++NLG+I +D+YHF+H KRS + H L
Sbjct: 70 YTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTLSSRGPHTFL 129
Query: 509 EGDSRVRWAEQQKILSRKKR 568
D +V+W +QQ++ R KR
Sbjct: 130 RMDPQVKWLQQQEVKRRVKR 149
Score = 33.9 bits (74), Expect(2) = 9e-16
Identities = 13/33 (39%), Positives = 19/33 (57%)
Frame = +2
Query: 668 ELNTRIRGRTRSADLKFILNDPKWPHMWYLNRG 766
E+ R++ + RS NDP W +MWYL+ G
Sbjct: 142 EVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCG 174
>AB001914-5|BAA21621.1| 652|Homo sapiens PACE4C protein.
Length = 652
Score = 69.7 bits (163), Expect(2) = 9e-16
Identities = 34/80 (42%), Positives = 47/80 (58%), Gaps = 2/80 (2%)
Frame = +2
Query: 335 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTPAHEHHGRL 508
YT WAV + G AD VA HG++NLG+I +D+YHF+H KRS + H L
Sbjct: 70 YTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTLSSRGPHTFL 129
Query: 509 EGDSRVRWAEQQKILSRKKR 568
D +V+W +QQ++ R KR
Sbjct: 130 RMDPQVKWLQQQEVKRRVKR 149
Score = 33.9 bits (74), Expect(2) = 9e-16
Identities = 13/33 (39%), Positives = 19/33 (57%)
Frame = +2
Query: 668 ELNTRIRGRTRSADLKFILNDPKWPHMWYLNRG 766
E+ R++ + RS NDP W +MWYL+ G
Sbjct: 142 EVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCG 174
>AB001914-6|BAA21623.1| 623|Homo sapiens PACE4CS protein.
Length = 623
Score = 69.7 bits (163), Expect(2) = 9e-16
Identities = 34/80 (42%), Positives = 47/80 (58%), Gaps = 2/80 (2%)
Frame = +2
Query: 335 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTPAHEHHGRL 508
YT WAV + G AD VA HG++NLG+I +D+YHF+H KRS + H L
Sbjct: 70 YTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTLSSRGPHTFL 129
Query: 509 EGDSRVRWAEQQKILSRKKR 568
D +V+W +QQ++ R KR
Sbjct: 130 RMDPQVKWLQQQEVKRRVKR 149
Score = 33.9 bits (74), Expect(2) = 9e-16
Identities = 13/33 (39%), Positives = 19/33 (57%)
Frame = +2
Query: 668 ELNTRIRGRTRSADLKFILNDPKWPHMWYLNRG 766
E+ R++ + RS NDP W +MWYL+ G
Sbjct: 142 EVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCG 174
>AB001914-7|BAA21620.1| 487|Homo sapiens PACE4B protein.
Length = 487
Score = 69.7 bits (163), Expect(2) = 9e-16
Identities = 34/80 (42%), Positives = 47/80 (58%), Gaps = 2/80 (2%)
Frame = +2
Query: 335 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTPAHEHHGRL 508
YT WAV + G AD VA HG++NLG+I +D+YHF+H KRS + H L
Sbjct: 70 YTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTLSSRGPHTFL 129
Query: 509 EGDSRVRWAEQQKILSRKKR 568
D +V+W +QQ++ R KR
Sbjct: 130 RMDPQVKWLQQQEVKRRVKR 149
Score = 33.9 bits (74), Expect(2) = 9e-16
Identities = 13/33 (39%), Positives = 19/33 (57%)
Frame = +2
Query: 668 ELNTRIRGRTRSADLKFILNDPKWPHMWYLNRG 766
E+ R++ + RS NDP W +MWYL+ G
Sbjct: 142 EVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCG 174
>AM491522-1|CAM33226.1| 357|Homo sapiens proprotein convertase
subtilisin/kexin type 6 protein.
Length = 357
Score = 59.7 bits (138), Expect(2) = 9e-13
Identities = 29/69 (42%), Positives = 41/69 (59%), Gaps = 2/69 (2%)
Frame = +2
Query: 368 GREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQ 541
G AD VA HG++NLG+I +D+YHF+H KRS + H L D +V+W +Q
Sbjct: 2 GPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTLSSRGPHTFLRMDPQVKWLQQ 61
Query: 542 QKILSRKKR 568
Q++ R KR
Sbjct: 62 QEVKRRVKR 70
Score = 33.9 bits (74), Expect(2) = 9e-13
Identities = 13/33 (39%), Positives = 19/33 (57%)
Frame = +2
Query: 668 ELNTRIRGRTRSADLKFILNDPKWPHMWYLNRG 766
E+ R++ + RS NDP W +MWYL+ G
Sbjct: 63 EVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCG 95
>AY358963-1|AAQ89322.1| 755|Homo sapiens prohormone convertase
protein.
Length = 755
Score = 70.9 bits (166), Expect = 5e-12
Identities = 32/80 (40%), Positives = 48/80 (60%), Gaps = 2/80 (2%)
Frame = +2
Query: 335 YTPTWAVHIPEGREVADAVARDHGFVNLGKIFDD--HYHFHHRSLTKRSLTPAHEHHGRL 508
Y +WAV + +G + +AR GFVNLG IF D ++H HR + ++SLTP H L
Sbjct: 34 YVSSWAVQVSQGNREVERLARKFGFVNLGPIFSDGQYFHLRHRGVVQQSLTPHWGHRLHL 93
Query: 509 EGDSRVRWAEQQKILSRKKR 568
+ + +V+W +QQ + R KR
Sbjct: 94 KKNPKVQWFQQQTLQRRVKR 113
>U56387-1|AAC50643.2| 913|Homo sapiens protease PC6 isoform A
protein.
Length = 913
Score = 67.7 bits (158), Expect = 4e-11
Identities = 31/82 (37%), Positives = 47/82 (57%), Gaps = 2/82 (2%)
Frame = +2
Query: 335 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTPAHEHHGRL 508
YT WAV I G A+ +A +GF+N+G+I D+YHF+H KRS+ + H +
Sbjct: 35 YTNHWAVKIAGGFPEANRIASKYGFINIGQIGALKDYYHFYHSRTIKRSVISSRGTHSFI 94
Query: 509 EGDSRVRWAEQQKILSRKKRDF 574
+ +V W +QQ + R KRD+
Sbjct: 95 SMEPKVEWIQQQVVKKRTKRDY 116
Score = 31.1 bits (67), Expect = 4.8
Identities = 9/12 (75%), Positives = 11/12 (91%)
Frame = +2
Query: 725 NDPKWPHMWYLN 760
NDPKWP MWY++
Sbjct: 127 NDPKWPSMWYMH 138
>U49114-1|AAA91807.1| 899|Homo sapiens prohormone convertase 5
precursor protein.
Length = 899
Score = 67.7 bits (158), Expect = 4e-11
Identities = 31/82 (37%), Positives = 47/82 (57%), Gaps = 2/82 (2%)
Frame = +2
Query: 335 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTPAHEHHGRL 508
YT WAV I G A+ +A +GF+N+G+I D+YHF+H KRS+ + H +
Sbjct: 21 YTNHWAVKIAGGFPEANRIASKYGFINIGQIGALKDYYHFYHSRTIKRSVISSRGTHSFI 80
Query: 509 EGDSRVRWAEQQKILSRKKRDF 574
+ +V W +QQ + R KRD+
Sbjct: 81 SMEPKVEWIQQQVVKKRTKRDY 102
Score = 31.1 bits (67), Expect = 4.8
Identities = 9/12 (75%), Positives = 11/12 (91%)
Frame = +2
Query: 725 NDPKWPHMWYLN 760
NDPKWP MWY++
Sbjct: 113 NDPKWPSMWYMH 124
>BC012064-1|AAH12064.1| 913|Homo sapiens proprotein convertase
subtilisin/kexin type 5 protein.
Length = 913
Score = 67.7 bits (158), Expect = 4e-11
Identities = 31/82 (37%), Positives = 47/82 (57%), Gaps = 2/82 (2%)
Frame = +2
Query: 335 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTPAHEHHGRL 508
YT WAV I G A+ +A +GF+N+G+I D+YHF+H KRS+ + H +
Sbjct: 35 YTNHWAVKIAGGFPEANRIASKYGFINIGQIGALKDYYHFYHSRTIKRSVISSRGTHSFI 94
Query: 509 EGDSRVRWAEQQKILSRKKRDF 574
+ +V W +QQ + R KRD+
Sbjct: 95 SMEPKVEWIQQQVVKKRTKRDY 116
Score = 31.1 bits (67), Expect = 4.8
Identities = 9/12 (75%), Positives = 11/12 (91%)
Frame = +2
Query: 725 NDPKWPHMWYLN 760
NDPKWP MWY++
Sbjct: 127 NDPKWPSMWYMH 138
>AL359253-2|CAH73743.1| 913|Homo sapiens proprotein convertase
subtilisin/kexin type 5 protein.
Length = 913
Score = 67.7 bits (158), Expect = 4e-11
Identities = 31/82 (37%), Positives = 47/82 (57%), Gaps = 2/82 (2%)
Frame = +2
Query: 335 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTPAHEHHGRL 508
YT WAV I G A+ +A +GF+N+G+I D+YHF+H KRS+ + H +
Sbjct: 35 YTNHWAVKIAGGFPEANRIASKYGFINIGQIGALKDYYHFYHSRTIKRSVISSRGTHSFI 94
Query: 509 EGDSRVRWAEQQKILSRKKRDF 574
+ +V W +QQ + R KRD+
Sbjct: 95 SMEPKVEWIQQQVVKKRTKRDY 116
Score = 31.1 bits (67), Expect = 4.8
Identities = 9/12 (75%), Positives = 11/12 (91%)
Frame = +2
Query: 725 NDPKWPHMWYLN 760
NDPKWP MWY++
Sbjct: 127 NDPKWPSMWYMH 138
>AL359253-1|CAH73742.1| 690|Homo sapiens proprotein convertase
subtilisin/kexin type 5 protein.
Length = 690
Score = 67.7 bits (158), Expect = 4e-11
Identities = 31/82 (37%), Positives = 47/82 (57%), Gaps = 2/82 (2%)
Frame = +2
Query: 335 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTPAHEHHGRL 508
YT WAV I G A+ +A +GF+N+G+I D+YHF+H KRS+ + H +
Sbjct: 35 YTNHWAVKIAGGFPEANRIASKYGFINIGQIGALKDYYHFYHSRTIKRSVISSRGTHSFI 94
Query: 509 EGDSRVRWAEQQKILSRKKRDF 574
+ +V W +QQ + R KRD+
Sbjct: 95 SMEPKVEWIQQQVVKKRTKRDY 116
Score = 31.1 bits (67), Expect = 4.8
Identities = 9/12 (75%), Positives = 11/12 (91%)
Frame = +2
Query: 725 NDPKWPHMWYLN 760
NDPKWP MWY++
Sbjct: 127 NDPKWPSMWYMH 138
>AL353607-2|CAI41233.1| 913|Homo sapiens proprotein convertase
subtilisin/kexin type 5 protein.
Length = 913
Score = 67.7 bits (158), Expect = 4e-11
Identities = 31/82 (37%), Positives = 47/82 (57%), Gaps = 2/82 (2%)
Frame = +2
Query: 335 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTPAHEHHGRL 508
YT WAV I G A+ +A +GF+N+G+I D+YHF+H KRS+ + H +
Sbjct: 35 YTNHWAVKIAGGFPEANRIASKYGFINIGQIGALKDYYHFYHSRTIKRSVISSRGTHSFI 94
Query: 509 EGDSRVRWAEQQKILSRKKRDF 574
+ +V W +QQ + R KRD+
Sbjct: 95 SMEPKVEWIQQQVVKKRTKRDY 116
Score = 31.1 bits (67), Expect = 4.8
Identities = 9/12 (75%), Positives = 11/12 (91%)
Frame = +2
Query: 725 NDPKWPHMWYLN 760
NDPKWP MWY++
Sbjct: 127 NDPKWPSMWYMH 138
>AL353607-1|CAI41232.1| 690|Homo sapiens proprotein convertase
subtilisin/kexin type 5 protein.
Length = 690
Score = 67.7 bits (158), Expect = 4e-11
Identities = 31/82 (37%), Positives = 47/82 (57%), Gaps = 2/82 (2%)
Frame = +2
Query: 335 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTPAHEHHGRL 508
YT WAV I G A+ +A +GF+N+G+I D+YHF+H KRS+ + H +
Sbjct: 35 YTNHWAVKIAGGFPEANRIASKYGFINIGQIGALKDYYHFYHSRTIKRSVISSRGTHSFI 94
Query: 509 EGDSRVRWAEQQKILSRKKRDF 574
+ +V W +QQ + R KRD+
Sbjct: 95 SMEPKVEWIQQQVVKKRTKRDY 116
Score = 31.1 bits (67), Expect = 4.8
Identities = 9/12 (75%), Positives = 11/12 (91%)
Frame = +2
Query: 725 NDPKWPHMWYLN 760
NDPKWP MWY++
Sbjct: 127 NDPKWPSMWYMH 138
>AB208955-1|BAD92192.1| 800|Homo sapiens paired basic amino acid
cleaving system 4 isoform a preproprotein variant
protein.
Length = 800
Score = 46.4 bits (105), Expect(2) = 7e-09
Identities = 22/54 (40%), Positives = 32/54 (59%), Gaps = 2/54 (3%)
Frame = +2
Query: 413 NLGKI--FDDHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQKILSRKKR 568
NLG+I +D+YHF+H KRS + H L D +V+W +QQ++ R KR
Sbjct: 1 NLGQIGNLEDYYHFYHSKTFKRSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKR 54
Score = 33.9 bits (74), Expect(2) = 7e-09
Identities = 13/33 (39%), Positives = 19/33 (57%)
Frame = +2
Query: 668 ELNTRIRGRTRSADLKFILNDPKWPHMWYLNRG 766
E+ R++ + RS NDP W +MWYL+ G
Sbjct: 47 EVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCG 79
>X64810-1|CAA46031.1| 753|Homo sapiens PC1/PC3 protein.
Length = 753
Score = 60.5 bits (140), Expect = 7e-09
Identities = 33/76 (43%), Positives = 42/76 (55%), Gaps = 2/76 (2%)
Frame = +2
Query: 347 WAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTPAHEHHGRLEGDS 520
WA IP G E A A+A + G+ LG+I ++HY F H++ +RS A RL D
Sbjct: 35 WAAEIPGGPEAASAIAEELGYDLLGQIGSLENHYLFKHKNHPRRSRRSAFHITKRLSDDD 94
Query: 521 RVRWAEQQKILSRKKR 568
RV WAEQQ R KR
Sbjct: 95 RVIWAEQQYEKERSKR 110
>M90753-1|AAA59918.1| 753|Homo sapiens PC1 protein.
Length = 753
Score = 60.5 bits (140), Expect = 7e-09
Identities = 33/76 (43%), Positives = 42/76 (55%), Gaps = 2/76 (2%)
Frame = +2
Query: 347 WAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTPAHEHHGRLEGDS 520
WA IP G E A A+A + G+ LG+I ++HY F H++ +RS A RL D
Sbjct: 35 WAAEIPGGPEAASAIAEELGYDLLGQIGSLENHYLFKHKNHPRRSRRSAFHITKRLSDDD 94
Query: 521 RVRWAEQQKILSRKKR 568
RV WAEQQ R KR
Sbjct: 95 RVIWAEQQYEKERSKR 110
>D73407-1|BAA11133.1| 753|Homo sapiens prohormone convertase 3
protein.
Length = 753
Score = 60.5 bits (140), Expect = 7e-09
Identities = 33/76 (43%), Positives = 42/76 (55%), Gaps = 2/76 (2%)
Frame = +2
Query: 347 WAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTPAHEHHGRLEGDS 520
WA IP G E A A+A + G+ LG+I ++HY F H++ +RS A RL D
Sbjct: 35 WAAEIPGGPEAASAIAEELGYDLLGQIGSLENHYLFKHKNHPRRSRRSAFHITKRLSDDD 94
Query: 521 RVRWAEQQKILSRKKR 568
RV WAEQQ R KR
Sbjct: 95 RVIWAEQQYEKERSKR 110
>BC130295-1|AAI30296.1| 753|Homo sapiens proprotein convertase
subtilisin/kexin type 1 protein.
Length = 753
Score = 60.5 bits (140), Expect = 7e-09
Identities = 33/76 (43%), Positives = 42/76 (55%), Gaps = 2/76 (2%)
Frame = +2
Query: 347 WAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTPAHEHHGRLEGDS 520
WA IP G E A A+A + G+ LG+I ++HY F H++ +RS A RL D
Sbjct: 35 WAAEIPGGPEAASAIAEELGYDLLGQIGSLENHYLFKHKNHPRRSRRSAFHITKRLSDDD 94
Query: 521 RVRWAEQQKILSRKKR 568
RV WAEQQ R KR
Sbjct: 95 RVIWAEQQYEKERSKR 110
>AB208874-1|BAD92111.1| 724|Homo sapiens proprotein convertase
subtilisin/kexin type 1 preproprotein variant protein.
Length = 724
Score = 60.5 bits (140), Expect = 7e-09
Identities = 33/76 (43%), Positives = 42/76 (55%), Gaps = 2/76 (2%)
Frame = +2
Query: 347 WAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTPAHEHHGRLEGDS 520
WA IP G E A A+A + G+ LG+I ++HY F H++ +RS A RL D
Sbjct: 6 WAAEIPGGPEAASAIAEELGYDLLGQIGSLENHYLFKHKNHPRRSRRSAFHITKRLSDDD 65
Query: 521 RVRWAEQQKILSRKKR 568
RV WAEQQ R KR
Sbjct: 66 RVIWAEQQYEKERSKR 81
>M95971-1|AAA59919.1| 638|Homo sapiens neuroendocrine convertase 2
protein.
Length = 638
Score = 49.2 bits (112), Expect(2) = 5e-06
Identities = 28/76 (36%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Frame = +2
Query: 368 GREVADAVARDHGF-VNLGKIFDDHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQ 544
G + A VA +HGF V + YHF+H L K + H +LE D RV+ A QQ
Sbjct: 42 GEDKARQVAAEHGFGVRKLPFAEGLYHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQ 101
Query: 545 KILSRKKRDFQIISTL 592
+ RKKR ++ I+ +
Sbjct: 102 EGFDRKKRGYRDINEI 117
Score = 21.4 bits (43), Expect(2) = 5e-06
Identities = 9/28 (32%), Positives = 13/28 (46%)
Frame = +2
Query: 686 RGRTRSADLKFILNDPKWPHMWYLNRGG 769
RG ++ +NDP + WYL G
Sbjct: 109 RGYRDINEIDINMNDPLFTKQWYLINTG 136
>J05252-1|AAA60032.1| 638|Homo sapiens endoprotease protein.
Length = 638
Score = 49.2 bits (112), Expect(2) = 5e-06
Identities = 28/76 (36%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Frame = +2
Query: 368 GREVADAVARDHGF-VNLGKIFDDHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQ 544
G + A VA +HGF V + YHF+H L K + H +LE D RV+ A QQ
Sbjct: 42 GEDKARQVAAEHGFGVRKLPFAEGLYHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQ 101
Query: 545 KILSRKKRDFQIISTL 592
+ RKKR ++ I+ +
Sbjct: 102 EGFDRKKRGYRDINEI 117
Score = 21.4 bits (43), Expect(2) = 5e-06
Identities = 9/28 (32%), Positives = 13/28 (46%)
Frame = +2
Query: 686 RGRTRSADLKFILNDPKWPHMWYLNRGG 769
RG ++ +NDP + WYL G
Sbjct: 109 RGYRDINEIDINMNDPLFTKQWYLINTG 136
>BC005815-1|AAH05815.1| 638|Homo sapiens proprotein convertase
subtilisin/kexin type 2 protein.
Length = 638
Score = 49.2 bits (112), Expect(2) = 5e-06
Identities = 28/76 (36%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Frame = +2
Query: 368 GREVADAVARDHGF-VNLGKIFDDHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQ 544
G + A VA +HGF V + YHF+H L K + H +LE D RV+ A QQ
Sbjct: 42 GEDKARQVAAEHGFGVRKLPFAEGLYHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQ 101
Query: 545 KILSRKKRDFQIISTL 592
+ RKKR ++ I+ +
Sbjct: 102 EGFDRKKRGYRDINEI 117
Score = 21.4 bits (43), Expect(2) = 5e-06
Identities = 9/28 (32%), Positives = 13/28 (46%)
Frame = +2
Query: 686 RGRTRSADLKFILNDPKWPHMWYLNRGG 769
RG ++ +NDP + WYL G
Sbjct: 109 RGYRDINEIDINMNDPLFTKQWYLINTG 136
>AL359511-2|CAI20085.1| 638|Homo sapiens proprotein convertase
subtilisin/kexin type 2 protein.
Length = 638
Score = 49.2 bits (112), Expect(2) = 5e-06
Identities = 28/76 (36%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Frame = +2
Query: 368 GREVADAVARDHGF-VNLGKIFDDHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQ 544
G + A VA +HGF V + YHF+H L K + H +LE D RV+ A QQ
Sbjct: 42 GEDKARQVAAEHGFGVRKLPFAEGLYHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQ 101
Query: 545 KILSRKKRDFQIISTL 592
+ RKKR ++ I+ +
Sbjct: 102 EGFDRKKRGYRDINEI 117
Score = 21.4 bits (43), Expect(2) = 5e-06
Identities = 9/28 (32%), Positives = 13/28 (46%)
Frame = +2
Query: 686 RGRTRSADLKFILNDPKWPHMWYLNRGG 769
RG ++ +NDP + WYL G
Sbjct: 109 RGYRDINEIDINMNDPLFTKQWYLINTG 136
>AL121779-1|CAI19155.1| 638|Homo sapiens proprotein convertase
subtilisin/kexin type 2 protein.
Length = 638
Score = 49.2 bits (112), Expect(2) = 5e-06
Identities = 28/76 (36%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Frame = +2
Query: 368 GREVADAVARDHGF-VNLGKIFDDHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQ 544
G + A VA +HGF V + YHF+H L K + H +LE D RV+ A QQ
Sbjct: 42 GEDKARQVAAEHGFGVRKLPFAEGLYHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQ 101
Query: 545 KILSRKKRDFQIISTL 592
+ RKKR ++ I+ +
Sbjct: 102 EGFDRKKRGYRDINEI 117
Score = 21.4 bits (43), Expect(2) = 5e-06
Identities = 9/28 (32%), Positives = 13/28 (46%)
Frame = +2
Query: 686 RGRTRSADLKFILNDPKWPHMWYLNRGG 769
RG ++ +NDP + WYL G
Sbjct: 109 RGYRDINEIDINMNDPLFTKQWYLINTG 136
>AL031675-1|CAI22648.1| 638|Homo sapiens proprotein convertase
subtilisin/kexin type 2 protein.
Length = 638
Score = 49.2 bits (112), Expect(2) = 5e-06
Identities = 28/76 (36%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Frame = +2
Query: 368 GREVADAVARDHGF-VNLGKIFDDHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQ 544
G + A VA +HGF V + YHF+H L K + H +LE D RV+ A QQ
Sbjct: 42 GEDKARQVAAEHGFGVRKLPFAEGLYHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQ 101
Query: 545 KILSRKKRDFQIISTL 592
+ RKKR ++ I+ +
Sbjct: 102 EGFDRKKRGYRDINEI 117
Score = 21.4 bits (43), Expect(2) = 5e-06
Identities = 9/28 (32%), Positives = 13/28 (46%)
Frame = +2
Query: 686 RGRTRSADLKFILNDPKWPHMWYLNRGG 769
RG ++ +NDP + WYL G
Sbjct: 109 RGYRDINEIDINMNDPLFTKQWYLINTG 136
>AL031664-2|CAI21690.1| 638|Homo sapiens proprotein convertase
subtilisin/kexin type 2 protein.
Length = 638
Score = 49.2 bits (112), Expect(2) = 5e-06
Identities = 28/76 (36%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Frame = +2
Query: 368 GREVADAVARDHGF-VNLGKIFDDHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQ 544
G + A VA +HGF V + YHF+H L K + H +LE D RV+ A QQ
Sbjct: 42 GEDKARQVAAEHGFGVRKLPFAEGLYHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQ 101
Query: 545 KILSRKKRDFQIISTL 592
+ RKKR ++ I+ +
Sbjct: 102 EGFDRKKRGYRDINEI 117
Score = 21.4 bits (43), Expect(2) = 5e-06
Identities = 9/28 (32%), Positives = 13/28 (46%)
Frame = +2
Query: 686 RGRTRSADLKFILNDPKWPHMWYLNRGG 769
RG ++ +NDP + WYL G
Sbjct: 109 RGYRDINEIDINMNDPLFTKQWYLINTG 136
>BC040546-1|AAH40546.1| 619|Homo sapiens PCSK2 protein protein.
Length = 619
Score = 49.2 bits (112), Expect(2) = 5e-06
Identities = 28/76 (36%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Frame = +2
Query: 368 GREVADAVARDHGF-VNLGKIFDDHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQ 544
G + A VA +HGF V + YHF+H L K + H +LE D RV+ A QQ
Sbjct: 23 GEDKARQVAAEHGFGVRKLPFAEGLYHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQ 82
Query: 545 KILSRKKRDFQIISTL 592
+ RKKR ++ I+ +
Sbjct: 83 EGFDRKKRGYRDINEI 98
Score = 21.4 bits (43), Expect(2) = 5e-06
Identities = 9/28 (32%), Positives = 13/28 (46%)
Frame = +2
Query: 686 RGRTRSADLKFILNDPKWPHMWYLNRGG 769
RG ++ +NDP + WYL G
Sbjct: 90 RGYRDINEIDINMNDPLFTKQWYLINTG 117
>AL359511-3|CAC34957.2| 619|Homo sapiens proprotein convertase
subtilisin/kexin type 2 protein.
Length = 619
Score = 49.2 bits (112), Expect(2) = 5e-06
Identities = 28/76 (36%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Frame = +2
Query: 368 GREVADAVARDHGF-VNLGKIFDDHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQ 544
G + A VA +HGF V + YHF+H L K + H +LE D RV+ A QQ
Sbjct: 23 GEDKARQVAAEHGFGVRKLPFAEGLYHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQ 82
Query: 545 KILSRKKRDFQIISTL 592
+ RKKR ++ I+ +
Sbjct: 83 EGFDRKKRGYRDINEI 98
Score = 21.4 bits (43), Expect(2) = 5e-06
Identities = 9/28 (32%), Positives = 13/28 (46%)
Frame = +2
Query: 686 RGRTRSADLKFILNDPKWPHMWYLNRGG 769
RG ++ +NDP + WYL G
Sbjct: 90 RGYRDINEIDINMNDPLFTKQWYLINTG 117
>AL121779-2|CAB96732.2| 619|Homo sapiens proprotein convertase
subtilisin/kexin type 2 protein.
Length = 619
Score = 49.2 bits (112), Expect(2) = 5e-06
Identities = 28/76 (36%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Frame = +2
Query: 368 GREVADAVARDHGF-VNLGKIFDDHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQ 544
G + A VA +HGF V + YHF+H L K + H +LE D RV+ A QQ
Sbjct: 23 GEDKARQVAAEHGFGVRKLPFAEGLYHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQ 82
Query: 545 KILSRKKRDFQIISTL 592
+ RKKR ++ I+ +
Sbjct: 83 EGFDRKKRGYRDINEI 98
Score = 21.4 bits (43), Expect(2) = 5e-06
Identities = 9/28 (32%), Positives = 13/28 (46%)
Frame = +2
Query: 686 RGRTRSADLKFILNDPKWPHMWYLNRGG 769
RG ++ +NDP + WYL G
Sbjct: 90 RGYRDINEIDINMNDPLFTKQWYLINTG 117
>AL031675-2|CAA21069.2| 619|Homo sapiens proprotein convertase
subtilisin/kexin type 2 protein.
Length = 619
Score = 49.2 bits (112), Expect(2) = 5e-06
Identities = 28/76 (36%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Frame = +2
Query: 368 GREVADAVARDHGF-VNLGKIFDDHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQ 544
G + A VA +HGF V + YHF+H L K + H +LE D RV+ A QQ
Sbjct: 23 GEDKARQVAAEHGFGVRKLPFAEGLYHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQ 82
Query: 545 KILSRKKRDFQIISTL 592
+ RKKR ++ I+ +
Sbjct: 83 EGFDRKKRGYRDINEI 98
Score = 21.4 bits (43), Expect(2) = 5e-06
Identities = 9/28 (32%), Positives = 13/28 (46%)
Frame = +2
Query: 686 RGRTRSADLKFILNDPKWPHMWYLNRGG 769
RG ++ +NDP + WYL G
Sbjct: 90 RGYRDINEIDINMNDPLFTKQWYLINTG 117
>AL031664-3|CAB89428.2| 619|Homo sapiens proprotein convertase
subtilisin/kexin type 2 protein.
Length = 619
Score = 49.2 bits (112), Expect(2) = 5e-06
Identities = 28/76 (36%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Frame = +2
Query: 368 GREVADAVARDHGF-VNLGKIFDDHYHFHHRSLTKRSLTPAHEHHGRLEGDSRVRWAEQQ 544
G + A VA +HGF V + YHF+H L K + H +LE D RV+ A QQ
Sbjct: 23 GEDKARQVAAEHGFGVRKLPFAEGLYHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQ 82
Query: 545 KILSRKKRDFQIISTL 592
+ RKKR ++ I+ +
Sbjct: 83 EGFDRKKRGYRDINEI 98
Score = 21.4 bits (43), Expect(2) = 5e-06
Identities = 9/28 (32%), Positives = 13/28 (46%)
Frame = +2
Query: 686 RGRTRSADLKFILNDPKWPHMWYLNRGG 769
RG ++ +NDP + WYL G
Sbjct: 90 RGYRDINEIDINMNDPLFTKQWYLINTG 117
>BT006870-1|AAP35516.1| 785|Homo sapiens proprotein convertase
subtilisin/kexin type 7 protein.
Length = 785
Score = 38.7 bits (86), Expect = 0.024
Identities = 32/92 (34%), Positives = 44/92 (47%), Gaps = 16/92 (17%)
Frame = +2
Query: 341 PTWAVHIP----EGREV-----ADAVARDHGFVNLGKI--FDDHYHF-----HHRSLTKR 472
P+WAVH+ +G E ADA+A+ G VN G+I HY F H +L
Sbjct: 52 PSWAVHLESLEGDGEEETLEQQADALAQAAGLVNAGRIGELQGHYLFVQPAGHRPALEVE 111
Query: 473 SLTPAHEHHGRLEGDSRVRWAEQQKILSRKKR 568
++ E L G VRW +Q++L R KR
Sbjct: 112 AIRQQVE--AVLAGHEAVRWHSEQRLLRRAKR 141
>BC010696-1|AAH10696.1| 785|Homo sapiens proprotein convertase
subtilisin/kexin type 7 protein.
Length = 785
Score = 38.7 bits (86), Expect = 0.024
Identities = 32/92 (34%), Positives = 44/92 (47%), Gaps = 16/92 (17%)
Frame = +2
Query: 341 PTWAVHIP----EGREV-----ADAVARDHGFVNLGKI--FDDHYHF-----HHRSLTKR 472
P+WAVH+ +G E ADA+A+ G VN G+I HY F H +L
Sbjct: 52 PSWAVHLESLEGDGEEETLEQQADALAQAAGLVNAGRIGELQGHYLFVQPAGHRPALEVE 111
Query: 473 SLTPAHEHHGRLEGDSRVRWAEQQKILSRKKR 568
++ E L G VRW +Q++L R KR
Sbjct: 112 AIRQQVE--AVLAGHEAVRWHSEQRLLRRAKR 141
>BC006357-1|AAH06357.1| 591|Homo sapiens PCSK7 protein protein.
Length = 591
Score = 38.7 bits (86), Expect = 0.024
Identities = 32/92 (34%), Positives = 44/92 (47%), Gaps = 16/92 (17%)
Frame = +2
Query: 341 PTWAVHIP----EGREV-----ADAVARDHGFVNLGKI--FDDHYHF-----HHRSLTKR 472
P+WAVH+ +G E ADA+A+ G VN G+I HY F H +L
Sbjct: 52 PSWAVHLESLEGDGEEETLEQQADALAQAAGLVNAGRIGELQGHYLFVQPAGHRPALEVE 111
Query: 473 SLTPAHEHHGRLEGDSRVRWAEQQKILSRKKR 568
++ E L G VRW +Q++L R KR
Sbjct: 112 AIRQQVE--AVLAGHEAVRWHSEQRLLRRAKR 141
>AK222907-1|BAD96627.1| 785|Homo sapiens proprotein convertase
subtilisin/kexin type 7 preproprotein variant protein.
Length = 785
Score = 38.7 bits (86), Expect = 0.024
Identities = 32/92 (34%), Positives = 44/92 (47%), Gaps = 16/92 (17%)
Frame = +2
Query: 341 PTWAVHIP----EGREV-----ADAVARDHGFVNLGKI--FDDHYHF-----HHRSLTKR 472
P+WAVH+ +G E ADA+A+ G VN G+I HY F H +L
Sbjct: 52 PSWAVHLESLEGDGEEETLEQQADALAQAAGLVNAGRIGELQGHYLFVQPAGHRPALEVE 111
Query: 473 SLTPAHEHHGRLEGDSRVRWAEQQKILSRKKR 568
++ E L G VRW +Q++L R KR
Sbjct: 112 AIRQQVE--AVLAGHEAVRWHSEQRLLRRAKR 141
>U40623-1|AAC50417.1| 785|Homo sapiens PC8 precursor protein.
Length = 785
Score = 35.9 bits (79), Expect = 0.17
Identities = 30/89 (33%), Positives = 43/89 (48%), Gaps = 14/89 (15%)
Frame = +2
Query: 344 TWAVHIP----EGREV-----ADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSL--TP 484
+WAVH+ +G E ADA+A+ G VN G+I HY F + + +L P
Sbjct: 53 SWAVHLESLEGDGEEETLEQQADALAQAAGLVNAGRIGELQGHYLFVQPAGHRPALEVEP 112
Query: 485 AHEH-HGRLEGDSRVRWAEQQKILSRKKR 568
+ L G VRW +Q++L R KR
Sbjct: 113 IRQQVEAVLAGHEAVRWHSEQRLLRRAKR 141
>U33849-1|AAB03087.1| 785|Homo sapiens lymphoma proprotein
convertase protein.
Length = 785
Score = 35.9 bits (79), Expect = 0.17
Identities = 30/89 (33%), Positives = 43/89 (48%), Gaps = 14/89 (15%)
Frame = +2
Query: 344 TWAVHIP----EGREV-----ADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSL--TP 484
+WAVH+ +G E ADA+A+ G VN G+I HY F + + +L P
Sbjct: 53 SWAVHLESLEGDGEEETLEQQADALAQAAGLVNAGRIGELQGHYLFVQPAGHRPALEVEP 112
Query: 485 AHEH-HGRLEGDSRVRWAEQQKILSRKKR 568
+ L G VRW +Q++L R KR
Sbjct: 113 IRQQVEAVLAGHEAVRWHSEQRLLRRAKR 141
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 112,888,059
Number of Sequences: 237096
Number of extensions: 2400497
Number of successful extensions: 5079
Number of sequences better than 10.0: 48
Number of HSP's better than 10.0 without gapping: 4791
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5047
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9701808132
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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