Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P06_F_P05
(877 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for ... 100 8e-21
M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA... 100 8e-21
M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrom... 100 8e-21
DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family ... 100 8e-21
DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family... 100 8e-21
BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfam... 100 8e-21
BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family... 100 8e-21
AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein. 100 8e-21
AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450 polypep... 100 8e-21
AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4 p... 100 8e-21
AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4 pro... 100 8e-21
J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipin... 99 1e-20
AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43... 98 3e-20
AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43... 98 3e-20
AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfami... 98 3e-20
AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43... 98 3e-20
AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfami... 98 3e-20
AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfami... 98 3e-20
AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfami... 98 3e-20
AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein. 98 3e-20
AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein. 98 3e-20
M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver glu... 98 4e-20
D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein. 98 4e-20
D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa pro... 94 7e-19
BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family... 94 7e-19
AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant... 94 7e-19
AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450 polypep... 94 7e-19
J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3 prot... 92 3e-18
DQ680079-1|ABG25922.1| 347|Homo sapiens truncated cytochrome P4... 92 3e-18
BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family... 92 3e-18
AF280111-1|AAG33012.1| 250|Homo sapiens cytochrome P450 subfami... 92 3e-18
AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein. 92 3e-18
AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family... 90 1e-17
AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein. 86 2e-16
AC004914-1|AAD21788.1| 348|Homo sapiens unknown protein. 71 7e-12
D34625-1|BAA07011.1| 533|Homo sapiens thromboxane synthase prot... 70 1e-11
BC041157-1|AAH41157.1| 534|Homo sapiens thromboxane A synthase ... 70 1e-11
AK223466-1|BAD97186.1| 534|Homo sapiens thromboxane A synthase ... 70 1e-11
AF233619-1|AAF99273.1| 534|Homo sapiens thromboxane synthase pr... 69 3e-11
AF233620-1|AAF99274.1| 534|Homo sapiens thromboxane synthase pr... 68 4e-11
M80647-1|AAA60618.1| 534|Homo sapiens thromboxane synthase prot... 68 5e-11
M80646-1|AAA60617.1| 460|Homo sapiens thromboxane synthase prot... 68 5e-11
AF233625-1|AAF99279.1| 534|Homo sapiens thromboxane synthase pr... 68 5e-11
AF233624-1|AAF99278.1| 534|Homo sapiens thromboxane synthase pr... 68 5e-11
AF233623-1|AAF99277.1| 534|Homo sapiens thromboxane synthase pr... 68 5e-11
AF233622-1|AAF99276.1| 534|Homo sapiens thromboxane synthase pr... 68 5e-11
AF233621-1|AAF99275.1| 534|Homo sapiens thromboxane synthase pr... 68 5e-11
AF233618-1|AAF99272.1| 534|Homo sapiens thromboxane synthase pr... 68 5e-11
AF233617-1|AAF99271.1| 534|Homo sapiens thromboxane synthase pr... 68 5e-11
AF233616-1|AAF99270.1| 534|Homo sapiens thromboxane synthase pr... 68 5e-11
AF233615-1|AAF99269.1| 534|Homo sapiens thromboxane synthase pr... 68 5e-11
L36085-1|AAC01761.1| 441|Homo sapiens thromboxane A2 synthase p... 67 7e-11
M74055-1|AAA36742.1| 229|Homo sapiens thromboxane synthase prot... 64 5e-10
AC004914-2|AAP21887.1| 311|Homo sapiens unknown protein. 64 6e-10
BC014117-1|AAH14117.1| 466|Homo sapiens TBXAS1 protein protein. 63 1e-09
AJ563377-1|CAD91345.1| 353|Homo sapiens cytochrome P450 protein. 40 0.009
AF280107-1|AAG32291.1| 106|Homo sapiens cytochrome P450 polypep... 40 0.012
AF280107-4|AAG32288.1| 106|Homo sapiens cytochrome P450 polypep... 32 2.4
BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family... 31 7.2
AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2 pro... 31 7.2
AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens ... 31 7.2
AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens ... 31 7.2
>X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (cyp3 locus). ).
Length = 503
Score = 100 bits (239), Expect = 8e-21
Identities = 70/238 (29%), Positives = 115/238 (48%), Gaps = 4/238 (1%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
++ LF K G+ G TPLPF GN+ F Y + G Y+ P++
Sbjct: 29 SHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYG-----KVWGFYDGQQPVLA 83
Query: 347 IRDIELLKKITVKD-FEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSS 523
I D +++K + VK+ + F + R F ++ D++WK +RS LSP FTS
Sbjct: 84 ITDPDMIKTVLVKECYSVFTNRRPF---GPVGFMKSAISIAEDEEWKRLRSLLSPTFTSG 140
Query: 524 KMKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSI 703
K+K M+P I + G + + L+ +EA G + KD+ Y+ DVI S +FG+ +DS+
Sbjct: 141 KLKEMVPIIAQYGDVLVRNLR---REAETG-KPVTLKDVFGAYSMDVITSTSFGVNIDSL 196
Query: 704 TEENNQFYAMGKAASTFNFRQLLIFFGLASVPXLV---KILRITLFQKEIKTFFRELI 868
+ F K F+F F + P L+ ++L I +F +E+ F R+ +
Sbjct: 197 NNPQDPFVENTKKLLRFDFLD-PFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSV 253
>M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA
encoding nifedipine oxidase, complete cds. ).
Length = 503
Score = 100 bits (239), Expect = 8e-21
Identities = 70/238 (29%), Positives = 115/238 (48%), Gaps = 4/238 (1%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
++ LF K G+ G TPLPF GN+ F Y + G Y+ P++
Sbjct: 29 SHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYG-----KVWGFYDGQQPVLA 83
Query: 347 IRDIELLKKITVKD-FEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSS 523
I D +++K + VK+ + F + R F ++ D++WK +RS LSP FTS
Sbjct: 84 ITDPDMIKTVLVKECYSVFTNRRPF---GPVGFMKSAISIAEDEEWKRLRSLLSPTFTSG 140
Query: 524 KMKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSI 703
K+K M+P I + G + + L+ +EA G + KD+ Y+ DVI S +FG+ +DS+
Sbjct: 141 KLKEMVPIIAQYGDVLVRNLR---REAETG-KPVTLKDVFGAYSMDVITSTSFGVNIDSL 196
Query: 704 TEENNQFYAMGKAASTFNFRQLLIFFGLASVPXLV---KILRITLFQKEIKTFFRELI 868
+ F K F+F F + P L+ ++L I +F +E+ F R+ +
Sbjct: 197 NNPQDPFVENTKKLLRFDFLD-PFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSV 253
>M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrome
P-450 nifedipine oxidase mRNA, complet cds. ).
Length = 503
Score = 100 bits (239), Expect = 8e-21
Identities = 70/238 (29%), Positives = 115/238 (48%), Gaps = 4/238 (1%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
++ LF K G+ G TPLPF GN+ F Y + G Y+ P++
Sbjct: 29 SHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYG-----KVWGFYDGQQPVLA 83
Query: 347 IRDIELLKKITVKD-FEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSS 523
I D +++K + VK+ + F + R F ++ D++WK +RS LSP FTS
Sbjct: 84 ITDPDMIKTVLVKECYSVFTNRRPF---GPVGFMKSAISIAEDEEWKRLRSLLSPTFTSG 140
Query: 524 KMKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSI 703
K+K M+P I + G + + L+ +EA G + KD+ Y+ DVI S +FG+ +DS+
Sbjct: 141 KLKEMVPIIAQYGDVLVRNLR---REAETG-KPVTLKDVFGAYSMDVITSTSFGVNIDSL 196
Query: 704 TEENNQFYAMGKAASTFNFRQLLIFFGLASVPXLV---KILRITLFQKEIKTFFRELI 868
+ F K F+F F + P L+ ++L I +F +E+ F R+ +
Sbjct: 197 NNPQDPFVENTKKLLRFDFLD-PFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSV 253
>DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family 3
subfamily A polypeptide 4 protein.
Length = 503
Score = 100 bits (239), Expect = 8e-21
Identities = 70/238 (29%), Positives = 115/238 (48%), Gaps = 4/238 (1%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
++ LF K G+ G TPLPF GN+ F Y + G Y+ P++
Sbjct: 29 SHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYG-----KVWGFYDGQQPVLA 83
Query: 347 IRDIELLKKITVKD-FEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSS 523
I D +++K + VK+ + F + R F ++ D++WK +RS LSP FTS
Sbjct: 84 ITDPDMIKTVLVKECYSVFTNRRPF---GPVGFMKSAISIAEDEEWKRLRSLLSPTFTSG 140
Query: 524 KMKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSI 703
K+K M+P I + G + + L+ +EA G + KD+ Y+ DVI S +FG+ +DS+
Sbjct: 141 KLKEMVPIIAQYGDVLVRNLR---REAETG-KPVTLKDVFGAYSMDVITSTSFGVNIDSL 196
Query: 704 TEENNQFYAMGKAASTFNFRQLLIFFGLASVPXLV---KILRITLFQKEIKTFFRELI 868
+ F K F+F F + P L+ ++L I +F +E+ F R+ +
Sbjct: 197 NNPQDPFVENTKKLLRFDFLD-PFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSV 253
>DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 100 bits (239), Expect = 8e-21
Identities = 70/238 (29%), Positives = 115/238 (48%), Gaps = 4/238 (1%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
++ LF K G+ G TPLPF GN+ F Y + G Y+ P++
Sbjct: 29 SHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYG-----KVWGFYDGQQPVLA 83
Query: 347 IRDIELLKKITVKD-FEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSS 523
I D +++K + VK+ + F + R F ++ D++WK +RS LSP FTS
Sbjct: 84 ITDPDMIKTVLVKECYSVFTNRRPF---GPVGFMKSAISIAEDEEWKRLRSLLSPTFTSG 140
Query: 524 KMKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSI 703
K+K M+P I + G + + L+ +EA G + KD+ Y+ DVI S +FG+ +DS+
Sbjct: 141 KLKEMVPIIAQYGDVLVRNLR---REAETG-KPVTLKDVFGAYSMDVITSTSFGVNIDSL 196
Query: 704 TEENNQFYAMGKAASTFNFRQLLIFFGLASVPXLV---KILRITLFQKEIKTFFRELI 868
+ F K F+F F + P L+ ++L I +F +E+ F R+ +
Sbjct: 197 NNPQDPFVENTKKLLRFDFLD-PFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSV 253
>BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfamily
IIIA, polypeptide 4 protein.
Length = 503
Score = 100 bits (239), Expect = 8e-21
Identities = 70/238 (29%), Positives = 115/238 (48%), Gaps = 4/238 (1%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
++ LF K G+ G TPLPF GN+ F Y + G Y+ P++
Sbjct: 29 SHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYG-----KVWGFYDGQQPVLA 83
Query: 347 IRDIELLKKITVKD-FEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSS 523
I D +++K + VK+ + F + R F ++ D++WK +RS LSP FTS
Sbjct: 84 ITDPDMIKTVLVKECYSVFTNRRPF---GPVGFMKSAISIAEDEEWKRLRSLLSPTFTSG 140
Query: 524 KMKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSI 703
K+K M+P I + G + + L+ +EA G + KD+ Y+ DVI S +FG+ +DS+
Sbjct: 141 KLKEMVPIIAQYGDVLVRNLR---REAETG-KPVTLKDVFGAYSMDVITSTSFGVNIDSL 196
Query: 704 TEENNQFYAMGKAASTFNFRQLLIFFGLASVPXLV---KILRITLFQKEIKTFFRELI 868
+ F K F+F F + P L+ ++L I +F +E+ F R+ +
Sbjct: 197 NNPQDPFVENTKKLLRFDFLD-PFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSV 253
>BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 100 bits (239), Expect = 8e-21
Identities = 70/238 (29%), Positives = 115/238 (48%), Gaps = 4/238 (1%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
++ LF K G+ G TPLPF GN+ F Y + G Y+ P++
Sbjct: 29 SHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYG-----KVWGFYDGQQPVLA 83
Query: 347 IRDIELLKKITVKD-FEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSS 523
I D +++K + VK+ + F + R F ++ D++WK +RS LSP FTS
Sbjct: 84 ITDPDMIKTVLVKECYSVFTNRRPF---GPVGFMKSAISIAEDEEWKRLRSLLSPTFTSG 140
Query: 524 KMKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSI 703
K+K M+P I + G + + L+ +EA G + KD+ Y+ DVI S +FG+ +DS+
Sbjct: 141 KLKEMVPIIAQYGDVLVRNLR---REAETG-KPVTLKDVFGAYSMDVITSTSFGVNIDSL 196
Query: 704 TEENNQFYAMGKAASTFNFRQLLIFFGLASVPXLV---KILRITLFQKEIKTFFRELI 868
+ F K F+F F + P L+ ++L I +F +E+ F R+ +
Sbjct: 197 NNPQDPFVENTKKLLRFDFLD-PFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSV 253
>AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein.
Length = 503
Score = 100 bits (239), Expect = 8e-21
Identities = 70/238 (29%), Positives = 115/238 (48%), Gaps = 4/238 (1%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
++ LF K G+ G TPLPF GN+ F Y + G Y+ P++
Sbjct: 29 SHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYG-----KVWGFYDGQQPVLA 83
Query: 347 IRDIELLKKITVKD-FEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSS 523
I D +++K + VK+ + F + R F ++ D++WK +RS LSP FTS
Sbjct: 84 ITDPDMIKTVLVKECYSVFTNRRPF---GPVGFMKSAISIAEDEEWKRLRSLLSPTFTSG 140
Query: 524 KMKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSI 703
K+K M+P I + G + + L+ +EA G + KD+ Y+ DVI S +FG+ +DS+
Sbjct: 141 KLKEMVPIIAQYGDVLVRNLR---REAETG-KPVTLKDVFGAYSMDVITSTSFGVNIDSL 196
Query: 704 TEENNQFYAMGKAASTFNFRQLLIFFGLASVPXLV---KILRITLFQKEIKTFFRELI 868
+ F K F+F F + P L+ ++L I +F +E+ F R+ +
Sbjct: 197 NNPQDPFVENTKKLLRFDFLD-PFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSV 253
>AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450
polypeptide 4 protein.
Length = 503
Score = 100 bits (239), Expect = 8e-21
Identities = 70/238 (29%), Positives = 115/238 (48%), Gaps = 4/238 (1%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
++ LF K G+ G TPLPF GN+ F Y + G Y+ P++
Sbjct: 29 SHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYG-----KVWGFYDGQQPVLA 83
Query: 347 IRDIELLKKITVKD-FEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSS 523
I D +++K + VK+ + F + R F ++ D++WK +RS LSP FTS
Sbjct: 84 ITDPDMIKTVLVKECYSVFTNRRPF---GPVGFMKSAISIAEDEEWKRLRSLLSPTFTSG 140
Query: 524 KMKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSI 703
K+K M+P I + G + + L+ +EA G + KD+ Y+ DVI S +FG+ +DS+
Sbjct: 141 KLKEMVPIIAQYGDVLVRNLR---REAETG-KPVTLKDVFGAYSMDVITSTSFGVNIDSL 196
Query: 704 TEENNQFYAMGKAASTFNFRQLLIFFGLASVPXLV---KILRITLFQKEIKTFFRELI 868
+ F K F+F F + P L+ ++L I +F +E+ F R+ +
Sbjct: 197 NNPQDPFVENTKKLLRFDFLD-PFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSV 253
>AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4
protein.
Length = 503
Score = 100 bits (239), Expect = 8e-21
Identities = 70/238 (29%), Positives = 115/238 (48%), Gaps = 4/238 (1%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
++ LF K G+ G TPLPF GN+ F Y + G Y+ P++
Sbjct: 29 SHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYG-----KVWGFYDGQQPVLA 83
Query: 347 IRDIELLKKITVKD-FEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSS 523
I D +++K + VK+ + F + R F ++ D++WK +RS LSP FTS
Sbjct: 84 ITDPDMIKTVLVKECYSVFTNRRPF---GPVGFMKSAISIAEDEEWKRLRSLLSPTFTSG 140
Query: 524 KMKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSI 703
K+K M+P I + G + + L+ +EA G + KD+ Y+ DVI S +FG+ +DS+
Sbjct: 141 KLKEMVPIIAQYGDVLVRNLR---REAETG-KPVTLKDVFGAYSMDVITSTSFGVNIDSL 196
Query: 704 TEENNQFYAMGKAASTFNFRQLLIFFGLASVPXLV---KILRITLFQKEIKTFFRELI 868
+ F K F+F F + P L+ ++L I +F +E+ F R+ +
Sbjct: 197 NNPQDPFVENTKKLLRFDFLD-PFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSV 253
>AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4
protein.
Length = 503
Score = 100 bits (239), Expect = 8e-21
Identities = 70/238 (29%), Positives = 115/238 (48%), Gaps = 4/238 (1%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
++ LF K G+ G TPLPF GN+ F Y + G Y+ P++
Sbjct: 29 SHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYG-----KVWGFYDGQQPVLA 83
Query: 347 IRDIELLKKITVKD-FEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSS 523
I D +++K + VK+ + F + R F ++ D++WK +RS LSP FTS
Sbjct: 84 ITDPDMIKTVLVKECYSVFTNRRPF---GPVGFMKSAISIAEDEEWKRLRSLLSPTFTSG 140
Query: 524 KMKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSI 703
K+K M+P I + G + + L+ +EA G + KD+ Y+ DVI S +FG+ +DS+
Sbjct: 141 KLKEMVPIIAQYGDVLVRNLR---REAETG-KPVTLKDVFGAYSMDVITSTSFGVNIDSL 196
Query: 704 TEENNQFYAMGKAASTFNFRQLLIFFGLASVPXLV---KILRITLFQKEIKTFFRELI 868
+ F K F+F F + P L+ ++L I +F +E+ F R+ +
Sbjct: 197 NNPQDPFVENTKKLLRFDFLD-PFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSV 253
>J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipine
oxidase protein.
Length = 502
Score = 99 bits (238), Expect = 1e-20
Identities = 72/238 (30%), Positives = 116/238 (48%), Gaps = 4/238 (1%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
++ LF K G+ G TPLPF GN+ F Y + G Y+ P++
Sbjct: 29 SHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYG-----KVCGFYDGQQPVLA 83
Query: 347 IRDIELLKKITVKD-FEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSS 523
I D +++K + VK+ + F + R F ++ D++WK +RS LSP FTS
Sbjct: 84 ITDPDMIKTVLVKECYSVFTNRRPF---GPVGFMKSAISIAEDEEWKRLRSLLSPTFTSG 140
Query: 524 KMKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSI 703
K+K M+P I + G + + L+ +EA G + KD+ Y+ DVI S +FG+ +DS+
Sbjct: 141 KLKEMVPIIAQYGDVLVRNLR---REAETG-KPVTLKDVFGAYSMDVITSTSFGVNIDSL 196
Query: 704 TEENNQFYAMGKAASTFNFRQLLIFFGLASVPXLV---KILRITLFQKEIKTFFRELI 868
+ F K F+F L FF P L+ ++L I +F +E+ F R+ +
Sbjct: 197 NNPQDPFVENTKKLLRFDF--LDPFFLSIIFPFLIPILEVLNICVFPREVTNFLRKSV 252
>AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43.1
protein.
Length = 503
Score = 98.3 bits (234), Expect = 3e-20
Identities = 68/236 (28%), Positives = 111/236 (47%), Gaps = 2/236 (0%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
++ LF K G+ G TPLPF G + + + +F Y G YE PM++
Sbjct: 29 SHKLFKKLGIPGPTPLPFLGTILFYLRGLWNFDRECNEKYGEM-----WGLYEGQQPMLV 83
Query: 347 IRDIELLKKITVKDFEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSSK 526
I D +++K + VK+ ++ + F +L F D++WK +R+ LSPAFTS K
Sbjct: 84 IMDPDMIKTVLVKECYSVFTNQMPLGPMG--FLKSALSFAEDEEWKRIRTLLSPAFTSVK 141
Query: 527 MKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSIT 706
K M+P I + G + ++L+Q + + I+ KD Y DVI FG+ +DS+
Sbjct: 142 FKEMVPIISQCGDMLVRSLRQEAENS----KSINLKDFFGAYTMDVITGTLFGVNLDSLN 197
Query: 707 EENNQFYAMGKAASTFNFRQ--LLIFFGLASVPXLVKILRITLFQKEIKTFFRELI 868
+ F K +F LL+ + + + L I LF K++ F + I
Sbjct: 198 NPQDPFLKNMKKLLKLDFLDPFLLLISLFPFLTPVFEALNIGLFPKDVTHFLKNSI 253
>AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43.3
protein.
Length = 503
Score = 98.3 bits (234), Expect = 3e-20
Identities = 68/236 (28%), Positives = 111/236 (47%), Gaps = 2/236 (0%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
++ LF K G+ G TPLPF G + + + +F Y G YE PM++
Sbjct: 29 SHKLFKKLGIPGPTPLPFLGTILFYLRGLWNFDRECNEKYGEM-----WGLYEGQQPMLV 83
Query: 347 IRDIELLKKITVKDFEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSSK 526
I D +++K + VK+ ++ + F +L F D++WK +R+ LSPAFTS K
Sbjct: 84 IMDPDMIKTVLVKECYSVFTNQMPLGPMG--FLKSALSFAEDEEWKRIRTLLSPAFTSVK 141
Query: 527 MKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSIT 706
K M+P I + G + ++L+Q + + I+ KD Y DVI FG+ +DS+
Sbjct: 142 FKEMVPIISQCGDMLVRSLRQEAENS----KSINLKDFFGAYTMDVITGTLFGVNLDSLN 197
Query: 707 EENNQFYAMGKAASTFNFRQ--LLIFFGLASVPXLVKILRITLFQKEIKTFFRELI 868
+ F K +F LL+ + + + L I LF K++ F + I
Sbjct: 198 NPQDPFLKNMKKLLKLDFLDPFLLLISLFPFLTPVFEALNIGLFPKDVTHFLKNSI 253
>AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 98.3 bits (234), Expect = 3e-20
Identities = 68/236 (28%), Positives = 111/236 (47%), Gaps = 2/236 (0%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
++ LF K G+ G TPLPF G + + + +F Y G YE PM++
Sbjct: 29 SHKLFKKLGIPGPTPLPFLGTILFYLRGLWNFDRECNEKYGEM-----WGLYEGQQPMLV 83
Query: 347 IRDIELLKKITVKDFEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSSK 526
I D +++K + VK+ ++ + F +L F D++WK +R+ LSPAFTS K
Sbjct: 84 IMDPDMIKTVLVKECYSVFTNQMPLGPMG--FLKSALSFAEDEEWKRIRTLLSPAFTSVK 141
Query: 527 MKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSIT 706
K M+P I + G + ++L+Q + + I+ KD Y DVI FG+ +DS+
Sbjct: 142 FKEMVPIISQCGDMLVRSLRQEAENS----KSINLKDFFGAYTMDVITGTLFGVNLDSLN 197
Query: 707 EENNQFYAMGKAASTFNFRQ--LLIFFGLASVPXLVKILRITLFQKEIKTFFRELI 868
+ F K +F LL+ + + + L I LF K++ F + I
Sbjct: 198 NPQDPFLKNMKKLLKLDFLDPFLLLISLFPFLTPVFEALNIGLFPKDVTHFLKNSI 253
>AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43
protein.
Length = 503
Score = 98.3 bits (234), Expect = 3e-20
Identities = 68/236 (28%), Positives = 111/236 (47%), Gaps = 2/236 (0%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
++ LF K G+ G TPLPF G + + + +F Y G YE PM++
Sbjct: 29 SHKLFKKLGIPGPTPLPFLGTILFYLRGLWNFDRECNEKYGEM-----WGLYEGQQPMLV 83
Query: 347 IRDIELLKKITVKDFEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSSK 526
I D +++K + VK+ ++ + F +L F D++WK +R+ LSPAFTS K
Sbjct: 84 IMDPDMIKTVLVKECYSVFTNQMPLGPMG--FLKSALSFAEDEEWKRIRTLLSPAFTSVK 141
Query: 527 MKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSIT 706
K M+P I + G + ++L+Q + + I+ KD Y DVI FG+ +DS+
Sbjct: 142 FKEMVPIISQCGDMLVRSLRQEAENS----KSINLKDFFGAYTMDVITGTLFGVNLDSLN 197
Query: 707 EENNQFYAMGKAASTFNFRQ--LLIFFGLASVPXLVKILRITLFQKEIKTFFRELI 868
+ F K +F LL+ + + + L I LF K++ F + I
Sbjct: 198 NPQDPFLKNMKKLLKLDFLDPFLLLISLFPFLTPVFEALNIGLFPKDVTHFLKNSI 253
>AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 420
Score = 98.3 bits (234), Expect = 3e-20
Identities = 68/236 (28%), Positives = 111/236 (47%), Gaps = 2/236 (0%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
++ LF K G+ G TPLPF G + + + +F Y G YE PM++
Sbjct: 29 SHKLFKKLGIPGPTPLPFLGTILFYLRGLWNFDRECNEKYGEM-----WGLYEGQQPMLV 83
Query: 347 IRDIELLKKITVKDFEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSSK 526
I D +++K + VK+ ++ + F +L F D++WK +R+ LSPAFTS K
Sbjct: 84 IMDPDMIKTVLVKECYSVFTNQMPLGPMG--FLKSALSFAEDEEWKRIRTLLSPAFTSVK 141
Query: 527 MKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSIT 706
K M+P I + G + ++L+Q + + I+ KD Y DVI FG+ +DS+
Sbjct: 142 FKEMVPIISQCGDMLVRSLRQEAENS----KSINLKDFFGAYTMDVITGTLFGVNLDSLN 197
Query: 707 EENNQFYAMGKAASTFNFRQ--LLIFFGLASVPXLVKILRITLFQKEIKTFFRELI 868
+ F K +F LL+ + + + L I LF K++ F + I
Sbjct: 198 NPQDPFLKNMKKLLKLDFLDPFLLLISLFPFLTPVFEALNIGLFPKDVTHFLKNSI 253
>AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 504
Score = 98.3 bits (234), Expect = 3e-20
Identities = 68/236 (28%), Positives = 111/236 (47%), Gaps = 2/236 (0%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
++ LF K G+ G TPLPF G + + + +F Y G YE PM++
Sbjct: 29 SHKLFKKLGIPGPTPLPFLGTILFYLRGLWNFDRECNEKYGEM-----WGLYEGQQPMLV 83
Query: 347 IRDIELLKKITVKDFEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSSK 526
I D +++K + VK+ ++ + F +L F D++WK +R+ LSPAFTS K
Sbjct: 84 IMDPDMIKTVLVKECYSVFTNQMPLGPMG--FLKSALSFAEDEEWKRIRTLLSPAFTSVK 141
Query: 527 MKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSIT 706
K M+P I + G + ++L+Q + + I+ KD Y DVI FG+ +DS+
Sbjct: 142 FKEMVPIISQCGDMLVRSLRQEAENS----KSINLKDFFGAYTMDVITGTLFGVNLDSLN 197
Query: 707 EENNQFYAMGKAASTFNFRQ--LLIFFGLASVPXLVKILRITLFQKEIKTFFRELI 868
+ F K +F LL+ + + + L I LF K++ F + I
Sbjct: 198 NPQDPFLKNMKKLLKLDFLDPFLLLISLFPFLTPVFEALNIGLFPKDVTHFLKNSI 253
>AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 98.3 bits (234), Expect = 3e-20
Identities = 68/236 (28%), Positives = 111/236 (47%), Gaps = 2/236 (0%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
++ LF K G+ G TPLPF G + + + +F Y G YE PM++
Sbjct: 29 SHKLFKKLGIPGPTPLPFLGTILFYLRGLWNFDRECNEKYGEM-----WGLYEGQQPMLV 83
Query: 347 IRDIELLKKITVKDFEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSSK 526
I D +++K + VK+ ++ + F +L F D++WK +R+ LSPAFTS K
Sbjct: 84 IMDPDMIKTVLVKECYSVFTNQMPLGPMG--FLKSALSFAEDEEWKRIRTLLSPAFTSVK 141
Query: 527 MKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSIT 706
K M+P I + G + ++L+Q + + I+ KD Y DVI FG+ +DS+
Sbjct: 142 FKEMVPIISQCGDMLVRSLRQEAENS----KSINLKDFFGAYTMDVITGTLFGVNLDSLN 197
Query: 707 EENNQFYAMGKAASTFNFRQ--LLIFFGLASVPXLVKILRITLFQKEIKTFFRELI 868
+ F K +F LL+ + + + L I LF K++ F + I
Sbjct: 198 NPQDPFLKNMKKLLKLDFLDPFLLLISLFPFLTPVFEALNIGLFPKDVTHFLKNSI 253
>AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein.
Length = 504
Score = 98.3 bits (234), Expect = 3e-20
Identities = 68/236 (28%), Positives = 111/236 (47%), Gaps = 2/236 (0%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
++ LF K G+ G TPLPF G + + + +F Y G YE PM++
Sbjct: 29 SHKLFKKLGIPGPTPLPFLGTILFYLRGLWNFDRECNEKYGEM-----WGLYEGQQPMLV 83
Query: 347 IRDIELLKKITVKDFEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSSK 526
I D +++K + VK+ ++ + F +L F D++WK +R+ LSPAFTS K
Sbjct: 84 IMDPDMIKTVLVKECYSVFTNQMPLGPMG--FLKSALSFAEDEEWKRIRTLLSPAFTSVK 141
Query: 527 MKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSIT 706
K M+P I + G + ++L+Q + + I+ KD Y DVI FG+ +DS+
Sbjct: 142 FKEMVPIISQCGDMLVRSLRQEAENS----KSINLKDFFGAYTMDVITGTLFGVNLDSLN 197
Query: 707 EENNQFYAMGKAASTFNFRQ--LLIFFGLASVPXLVKILRITLFQKEIKTFFRELI 868
+ F K +F LL+ + + + L I LF K++ F + I
Sbjct: 198 NPQDPFLKNMKKLLKLDFLDPFLLLISLFPFLTPVFEALNIGLFPKDVTHFLKNSI 253
>AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein.
Length = 503
Score = 98.3 bits (234), Expect = 3e-20
Identities = 68/236 (28%), Positives = 111/236 (47%), Gaps = 2/236 (0%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
++ LF K G+ G TPLPF G + + + +F Y G YE PM++
Sbjct: 29 SHKLFKKLGIPGPTPLPFLGTILFYLRGLWNFDRECNEKYGEM-----WGLYEGQQPMLV 83
Query: 347 IRDIELLKKITVKDFEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSSK 526
I D +++K + VK+ ++ + F +L F D++WK +R+ LSPAFTS K
Sbjct: 84 IMDPDMIKTVLVKECYSVFTNQMPLGPMG--FLKSALSFAEDEEWKRIRTLLSPAFTSVK 141
Query: 527 MKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSIT 706
K M+P I + G + ++L+Q + + I+ KD Y DVI FG+ +DS+
Sbjct: 142 FKEMVPIISQCGDMLVRSLRQEAENS----KSINLKDFFGAYTMDVITGTLFGVNLDSLN 197
Query: 707 EENNQFYAMGKAASTFNFRQ--LLIFFGLASVPXLVKILRITLFQKEIKTFFRELI 868
+ F K +F LL+ + + + L I LF K++ F + I
Sbjct: 198 NPQDPFLKNMKKLLKLDFLDPFLLLISLFPFLTPVFEALNIGLFPKDVTHFLKNSI 253
>M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver
glucocorticoid-inducible cytochrome P-450 (HLp) mRNA,
complete cds. ).
Length = 504
Score = 97.9 bits (233), Expect = 4e-20
Identities = 69/237 (29%), Positives = 112/237 (47%), Gaps = 3/237 (1%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
++ LF K G+ G TPLPF GN+ F Y + G Y+ P++
Sbjct: 29 SHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYG-----KVWGFYDGQQPVLA 83
Query: 347 IRDIELLKKITVKDFEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSSK 526
I D +++K + VK+ +R F ++ D++WK +RS LSP FTS K
Sbjct: 84 ITDPDMIKLVLVKECYSVFTNREPFGPVG--FMKSAISIAEDEEWKRLRSLLSPTFTSGK 141
Query: 527 MKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSIT 706
+K M+P I + G + + L+ R +E G + KD+ Y+ DVI S +FG+ VDS+
Sbjct: 142 LKEMVPIIAQYGDVLVRNLR-RERETG---KPVTLKDVFGAYSMDVITSSSFGVNVDSLN 197
Query: 707 EENNQFYAMGKAASTFNFRQLLIFFGLASVPXLV---KILRITLFQKEIKTFFRELI 868
+ K F+F F + P L+ ++L I +F +E+ F R+ +
Sbjct: 198 NPQDPLVENTKKLLRFDFLD-PFFLSITVFPFLIPILEVLNICVFPREVTNFLRKAV 253
>D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein.
Length = 504
Score = 97.9 bits (233), Expect = 4e-20
Identities = 69/237 (29%), Positives = 112/237 (47%), Gaps = 3/237 (1%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
++ LF K G+ G TPLPF GN+ F Y + G Y+ P++
Sbjct: 29 SHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYG-----KVWGFYDGQQPVLA 83
Query: 347 IRDIELLKKITVKDFEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSSK 526
I D +++K + VK+ +R F ++ D++WK +RS LSP FTS K
Sbjct: 84 ITDPDMIKLVLVKECYSVFTNREPFGPVG--FMKSAISIAEDEEWKRLRSLLSPTFTSGK 141
Query: 527 MKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSIT 706
+K M+P I + G + + L+ R +E G + KD+ Y+ DVI S +FG+ VDS+
Sbjct: 142 LKEMVPIIAQYGDVLVRNLR-RERETG---KPVTLKDVFGAYSMDVITSSSFGVNVDSLN 197
Query: 707 EENNQFYAMGKAASTFNFRQLLIFFGLASVPXLV---KILRITLFQKEIKTFFRELI 868
+ K F+F F + P L+ ++L I +F +E+ F R+ +
Sbjct: 198 NPQDPLVENTKKLLRFDFLD-PFFLSITVFPFLIPILEVLNICVFPREVTNFLRKAV 253
>D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa
protein.
Length = 503
Score = 93.9 bits (223), Expect = 7e-19
Identities = 68/239 (28%), Positives = 118/239 (49%), Gaps = 4/239 (1%)
Frame = +2
Query: 164 QAYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMV 343
+ + LF K G+ G TPLPF GN + + +++ ++ Y + + G Y+ PM+
Sbjct: 28 RTHGLFKKLGIPGPTPLPFLGNA--LSFRKGYWTFDMEC-YKKY--RKVWGIYDCQQPML 82
Query: 344 IIRDIELLKKITVKD-FEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTS 520
I D +++K + VK+ + F + R F ++ D++WK +RS LSP FTS
Sbjct: 83 AITDPDMIKTVLVKECYSVFTNRRPF---GPVGFMKNAISIAEDEEWKRIRSLLSPTFTS 139
Query: 521 SKMKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDS 700
K+K M+P I + G + + L+ +EA G + K + Y+ DVI S +FG+ +DS
Sbjct: 140 GKLKEMVPIIAQYGDVLVRNLR---REAETG-KPVTLKHVFGAYSMDVITSTSFGVSIDS 195
Query: 701 ITEENNQFYAMGKAASTFNFRQLLIFFGLASVPXLVKI---LRITLFQKEIKTFFRELI 868
+ + F K FN + + P L I L IT+F +++ +F + +
Sbjct: 196 LNNPQDPFVENTKKLLRFNPLDPFV-LSIKVFPFLTPILEALNITVFPRKVISFLTKSV 253
>BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 7 protein.
Length = 503
Score = 93.9 bits (223), Expect = 7e-19
Identities = 68/239 (28%), Positives = 118/239 (49%), Gaps = 4/239 (1%)
Frame = +2
Query: 164 QAYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMV 343
+ + LF K G+ G TPLPF GN + + +++ ++ Y + + G Y+ PM+
Sbjct: 28 RTHGLFKKLGIPGPTPLPFLGNA--LSFRKGYWTFDMEC-YKKY--RKVWGIYDCQQPML 82
Query: 344 IIRDIELLKKITVKD-FEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTS 520
I D +++K + VK+ + F + R F ++ D++WK +RS LSP FTS
Sbjct: 83 AITDPDMIKTVLVKECYSVFTNRRPF---GPVGFMKNAISIAEDEEWKRIRSLLSPTFTS 139
Query: 521 SKMKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDS 700
K+K M+P I + G + + L+ +EA G + K + Y+ DVI S +FG+ +DS
Sbjct: 140 GKLKEMVPIIAQYGDVLVRNLR---REAETG-KPVTLKHVFGAYSMDVITSTSFGVSIDS 195
Query: 701 ITEENNQFYAMGKAASTFNFRQLLIFFGLASVPXLVKI---LRITLFQKEIKTFFRELI 868
+ + F K FN + + P L I L IT+F +++ +F + +
Sbjct: 196 LNNPQDPFVENTKKLLRFNPLDPFV-LSIKVFPFLTPILEALNITVFPRKVISFLTKSV 253
>AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant
3A7 protein.
Length = 535
Score = 93.9 bits (223), Expect = 7e-19
Identities = 68/239 (28%), Positives = 118/239 (49%), Gaps = 4/239 (1%)
Frame = +2
Query: 164 QAYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMV 343
+ + LF K G+ G TPLPF GN + + +++ ++ Y + + G Y+ PM+
Sbjct: 28 RTHGLFKKLGIPGPTPLPFLGNA--LSFRKGYWTFDMEC-YKKY--RKVWGIYDCQQPML 82
Query: 344 IIRDIELLKKITVKD-FEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTS 520
I D +++K + VK+ + F + R F ++ D++WK +RS LSP FTS
Sbjct: 83 AITDPDMIKTVLVKECYSVFTNRRPF---GPVGFMKNAISIAEDEEWKRIRSLLSPTFTS 139
Query: 521 SKMKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDS 700
K+K M+P I + G + + L+ +EA G + K + Y+ DVI S +FG+ +DS
Sbjct: 140 GKLKEMVPIIAQYGDVLVRNLR---REAETG-KPVTLKHVFGAYSMDVITSTSFGVSIDS 195
Query: 701 ITEENNQFYAMGKAASTFNFRQLLIFFGLASVPXLVKI---LRITLFQKEIKTFFRELI 868
+ + F K FN + + P L I L IT+F +++ +F + +
Sbjct: 196 LNNPQDPFVENTKKLLRFNPLDPFV-LSIKVFPFLTPILEALNITVFPRKVISFLTKSV 253
>AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450
polypeptide 7 protein.
Length = 503
Score = 93.9 bits (223), Expect = 7e-19
Identities = 68/239 (28%), Positives = 118/239 (49%), Gaps = 4/239 (1%)
Frame = +2
Query: 164 QAYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMV 343
+ + LF K G+ G TPLPF GN + + +++ ++ Y + + G Y+ PM+
Sbjct: 28 RTHGLFKKLGIPGPTPLPFLGNA--LSFRKGYWTFDMEC-YKKY--RKVWGIYDCQQPML 82
Query: 344 IIRDIELLKKITVKD-FEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTS 520
I D +++K + VK+ + F + R F ++ D++WK +RS LSP FTS
Sbjct: 83 AITDPDMIKTVLVKECYSVFTNRRPF---GPVGFMKNAISIAEDEEWKRIRSLLSPTFTS 139
Query: 521 SKMKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDS 700
K+K M+P I + G + + L+ +EA G + K + Y+ DVI S +FG+ +DS
Sbjct: 140 GKLKEMVPIIAQYGDVLVRNLR---REAETG-KPVTLKHVFGAYSMDVITSTSFGVSIDS 195
Query: 701 ITEENNQFYAMGKAASTFNFRQLLIFFGLASVPXLVKI---LRITLFQKEIKTFFRELI 868
+ + F K FN + + P L I L IT+F +++ +F + +
Sbjct: 196 LNNPQDPFVENTKKLLRFNPLDPFV-LSIKVFPFLTPILEALNITVFPRKVISFLTKSV 253
>J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3
protein.
Length = 502
Score = 91.9 bits (218), Expect = 3e-18
Identities = 64/239 (26%), Positives = 111/239 (46%), Gaps = 4/239 (1%)
Frame = +2
Query: 164 QAYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMV 343
+ + LF + G+ G TPLP GN+ + F Y + G YE P++
Sbjct: 28 RTHGLFKRLGIPGPTPLPLLGNVLSYRQGLWKFDTECYKKYG-----KMWGTYEGQLPVL 82
Query: 344 IIRDIELLKKITVKD-FEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTS 520
I D ++++ + VK+ + F + R++ F ++ D++WK +RS LSP FTS
Sbjct: 83 AITDPDVIRTVLVKECYSVFTNRRSL---GPVGFMKSAISLAEDEEWKRIRSLLSPTFTS 139
Query: 521 SKMKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDS 700
K+K M P I + G + + L++ ++ + KD+ Y+ DVI +FG+ +DS
Sbjct: 140 GKLKEMFPIIAQYGDVLVRNLRREAEKG----KPVTLKDIFGAYSMDVITGTSFGVNIDS 195
Query: 701 ITEENNQFYAMGKAASTFNFRQLLIFFGLASVPXLVKI---LRITLFQKEIKTFFRELI 868
+ + F K F F L F + P L + L ++LF K+ F + +
Sbjct: 196 LNNPQDPFVESTKKFLKFGFLDPL-FLSIILFPFLTPVFEALNVSLFPKDTINFLSKSV 253
>DQ680079-1|ABG25922.1| 347|Homo sapiens truncated cytochrome P450,
family 3, subfamily A, polypeptide 5 protein.
Length = 347
Score = 91.9 bits (218), Expect = 3e-18
Identities = 64/239 (26%), Positives = 111/239 (46%), Gaps = 4/239 (1%)
Frame = +2
Query: 164 QAYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMV 343
+ + LF + G+ G TPLP GN+ + F Y + G YE P++
Sbjct: 28 RTHGLFKRLGIPGPTPLPLLGNVLSYRQGLWKFDTECYKKYG-----KMWGTYEGQLPVL 82
Query: 344 IIRDIELLKKITVKD-FEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTS 520
I D ++++ + VK+ + F + R++ F ++ D++WK +RS LSP FTS
Sbjct: 83 AITDPDVIRTVLVKECYSVFTNRRSL---GPVGFMKSAISLAEDEEWKRIRSLLSPTFTS 139
Query: 521 SKMKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDS 700
K+K M P I + G + + L++ ++ + KD+ Y+ DVI +FG+ +DS
Sbjct: 140 GKLKEMFPIIAQYGDVLVRNLRREAEKG----KPVTLKDIFGAYSMDVITGTSFGVNIDS 195
Query: 701 ITEENNQFYAMGKAASTFNFRQLLIFFGLASVPXLVKI---LRITLFQKEIKTFFRELI 868
+ + F K F F L F + P L + L ++LF K+ F + +
Sbjct: 196 LNNPQDPFVESTKKFLKFGFLDPL-FLSIILFPFLTPVFEALNVSLFPKDTINFLSKSV 253
>BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 protein.
Length = 502
Score = 91.9 bits (218), Expect = 3e-18
Identities = 64/239 (26%), Positives = 111/239 (46%), Gaps = 4/239 (1%)
Frame = +2
Query: 164 QAYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMV 343
+ + LF + G+ G TPLP GN+ + F Y + G YE P++
Sbjct: 28 RTHGLFKRLGIPGPTPLPLLGNVLSYRQGLWKFDTECYKKYG-----KMWGTYEGQLPVL 82
Query: 344 IIRDIELLKKITVKD-FEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTS 520
I D ++++ + VK+ + F + R++ F ++ D++WK +RS LSP FTS
Sbjct: 83 AITDPDVIRTVLVKECYSVFTNRRSL---GPVGFMKSAISLAEDEEWKRIRSLLSPTFTS 139
Query: 521 SKMKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDS 700
K+K M P I + G + + L++ ++ + KD+ Y+ DVI +FG+ +DS
Sbjct: 140 GKLKEMFPIIAQYGDVLVRNLRREAEKG----KPVTLKDIFGAYSMDVITGTSFGVNIDS 195
Query: 701 ITEENNQFYAMGKAASTFNFRQLLIFFGLASVPXLVKI---LRITLFQKEIKTFFRELI 868
+ + F K F F L F + P L + L ++LF K+ F + +
Sbjct: 196 LNNPQDPFVESTKKFLKFGFLDPL-FLSIILFPFLTPVFEALNVSLFPKDTINFLSKSV 253
>AF280111-1|AAG33012.1| 250|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 250
Score = 91.9 bits (218), Expect = 3e-18
Identities = 57/186 (30%), Positives = 92/186 (49%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
++ LF K G+ G TPLPF G + + + +F Y G YE PM++
Sbjct: 29 SHKLFKKLGIPGPTPLPFLGTILFYLRGLWNFDRECNEKYGEM-----WGLYEGQQPMLV 83
Query: 347 IRDIELLKKITVKDFEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSSK 526
I D +++K + VK+ ++ + F +L F D++WK +R+ LSPAFTS K
Sbjct: 84 IMDPDMIKTVLVKECYSVFTNQMPLGPMG--FLKSALSFAEDEEWKRIRTLLSPAFTSVK 141
Query: 527 MKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSIT 706
K M+P I + G + ++L+Q + + I+ KD Y DVI FG+ +DS+
Sbjct: 142 FKEMVPIISQCGDMLVRSLRQEAENS----KSINLKDFFGAYTMDVITGTLFGVNLDSLN 197
Query: 707 EENNQF 724
+ F
Sbjct: 198 NPQDPF 203
>AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein.
Length = 502
Score = 91.9 bits (218), Expect = 3e-18
Identities = 64/239 (26%), Positives = 111/239 (46%), Gaps = 4/239 (1%)
Frame = +2
Query: 164 QAYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMV 343
+ + LF + G+ G TPLP GN+ + F Y + G YE P++
Sbjct: 28 RTHGLFKRLGIPGPTPLPLLGNVLSYRQGLWKFDTECYKKYG-----KMWGTYEGQLPVL 82
Query: 344 IIRDIELLKKITVKD-FEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTS 520
I D ++++ + VK+ + F + R++ F ++ D++WK +RS LSP FTS
Sbjct: 83 AITDPDVIRTVLVKECYSVFTNRRSL---GPVGFMKSAISLAEDEEWKRIRSLLSPTFTS 139
Query: 521 SKMKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDS 700
K+K M P I + G + + L++ ++ + KD+ Y+ DVI +FG+ +DS
Sbjct: 140 GKLKEMFPIIAQYGDVLVRNLRREAEKG----KPVTLKDIFGAYSMDVITGTSFGVNIDS 195
Query: 701 ITEENNQFYAMGKAASTFNFRQLLIFFGLASVPXLVKI---LRITLFQKEIKTFFRELI 868
+ + F K F F L F + P L + L ++LF K+ F + +
Sbjct: 196 LNNPQDPFVESTKKFLKFGFLDPL-FLSIILFPFLTPVFEALNVSLFPKDTINFLSKSV 253
>AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 variant protein.
Length = 502
Score = 89.8 bits (213), Expect = 1e-17
Identities = 63/239 (26%), Positives = 110/239 (46%), Gaps = 4/239 (1%)
Frame = +2
Query: 164 QAYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMV 343
+ + LF + G+ G TPLP GN+ + F Y + G YE P++
Sbjct: 28 RTHGLFKRLGIPGPTPLPLLGNVLSYRQGLWKFDTECYKKYG-----KMWGTYEGQLPVL 82
Query: 344 IIRDIELLKKITVKD-FEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTS 520
I D ++++ + VK+ + F + R++ F ++ D++WK +R LSP FTS
Sbjct: 83 AITDPDVIRTVLVKECYSVFTNRRSL---GPVGFMKSAISLAEDEEWKRIRPLLSPTFTS 139
Query: 521 SKMKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDS 700
K+K M P I + G + + L++ ++ + KD+ Y+ DVI +FG+ +DS
Sbjct: 140 GKLKEMFPIIAQYGDVLVRNLRREAEKG----KPVTLKDIFGAYSMDVITGTSFGVNIDS 195
Query: 701 ITEENNQFYAMGKAASTFNFRQLLIFFGLASVPXLVKI---LRITLFQKEIKTFFRELI 868
+ + F K F F L F + P L + L ++LF K+ F + +
Sbjct: 196 LNNPQDPFVESTKKFLKFGFLDPL-FLSIILFPFLTPVFEALNVSLFPKDTINFLSKSV 253
>AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein.
Length = 430
Score = 85.8 bits (203), Expect = 2e-16
Identities = 55/187 (29%), Positives = 95/187 (50%), Gaps = 4/187 (2%)
Frame = +2
Query: 320 YEFLNPMVIIRDIELLKKITVKD-FEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRS 496
Y+ P++ I D +++K + VK+ + F + R F ++ D++WK +RS
Sbjct: 2 YDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPF---GPVGFMKSAISIAEDEEWKRLRS 58
Query: 497 TLSPAFTSSKMKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASC 676
LSP FTS K+K M+P I + G + + L+ +EA G + KD+ Y+ DVI S
Sbjct: 59 LLSPTFTSGKLKEMVPIIAQYGDVLVRNLR---REAETG-KPVTLKDVFGAYSMDVITST 114
Query: 677 AFGLKVDSITEENNQFYAMGKAASTFNFRQLLIFFGLASVPXLV---KILRITLFQKEIK 847
+FG+ +DS+ + F K F+F F + P L+ ++L I +F +E+
Sbjct: 115 SFGVNIDSLNNPQDPFVENTKKLLRFDFLD-PFFLSITVFPFLIPILEVLNICVFPREVT 173
Query: 848 TFFRELI 868
F R+ +
Sbjct: 174 NFLRKSV 180
>AC004914-1|AAD21788.1| 348|Homo sapiens unknown protein.
Length = 348
Score = 70.5 bits (165), Expect = 7e-12
Identities = 62/236 (26%), Positives = 109/236 (46%), Gaps = 2/236 (0%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
A+S K G++ P PF GN+ ++ LY ++GR F ++
Sbjct: 5 AFSRLEKLGLRHPKPSPFIGNLTFFRQGFWESQMELRKLYGPLCGY-YLGRRMF----IV 59
Query: 347 IRDIELLKKITVKDFEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSSK 526
I + +++K++ V++F +F + + + S+ FLRD+ W+++R L AF+ K
Sbjct: 60 ISEPDMIKQVLVENFSNFTNR--MASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSPEK 117
Query: 527 MKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSIT 706
+ M+P I + + + LK R E+G + D + Y DV+AS AFG VDS
Sbjct: 118 LNEMVPLISQACELLLAHLK-RYAESGDAF---DIQRCYCNYTTDVVASVAFGTPVDSWQ 173
Query: 707 EENNQFYAMGKAASTFNFRQLLIFFGLASVPXLVKILRI--TLFQKEIKTFFRELI 868
+ F K F + ++ L+ +V + RI + E+ FF +LI
Sbjct: 174 APEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLI 229
>D34625-1|BAA07011.1| 533|Homo sapiens thromboxane synthase
protein.
Length = 533
Score = 69.7 bits (163), Expect = 1e-11
Identities = 62/236 (26%), Positives = 108/236 (45%), Gaps = 2/236 (0%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
A+S K G++ P PF GN+ ++ LY ++GR F ++
Sbjct: 35 AFSRLEKLGLRHPKPSPFIGNLTFFRQGFWESQMELRKLYGPLCGY-YLGRRMF----IV 89
Query: 347 IRDIELLKKITVKDFEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSSK 526
I + +++K++ V++F +F + + + S+ FLRD+ W+++R L AF+ K
Sbjct: 90 ISEPDMIKQVLVENFSNFTNR--MASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSPEK 147
Query: 527 MKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSIT 706
+ M+P I + + LK R E+G + D + Y DV+AS AFG VDS
Sbjct: 148 LNEMVPLISQACDLLLAHLK-RYAESGDAF---DIQRCYCNYTTDVVASVAFGTPVDSWQ 203
Query: 707 EENNQFYAMGKAASTFNFRQLLIFFGLASVPXLVKILRI--TLFQKEIKTFFRELI 868
+ F K F + ++ L+ +V + RI + E+ FF +LI
Sbjct: 204 APEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLI 259
>BC041157-1|AAH41157.1| 534|Homo sapiens thromboxane A synthase 1
(platelet, cytochrome P450, family 5, subfamily A)
protein.
Length = 534
Score = 69.7 bits (163), Expect = 1e-11
Identities = 62/236 (26%), Positives = 108/236 (45%), Gaps = 2/236 (0%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
A+S K G++ P PF GN+ ++ LY ++GR F ++
Sbjct: 36 AFSRLEKLGLRHPKPSPFIGNLTFFRQGFWESQMELRKLYGPLCGY-YLGRRMF----IV 90
Query: 347 IRDIELLKKITVKDFEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSSK 526
I + +++K++ V++F +F + + + S+ FLRD+ W+++R L AF+ K
Sbjct: 91 ISEPDMIKQVLVENFSNFTNR--MASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSPEK 148
Query: 527 MKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSIT 706
+ M+P I + + LK R E+G + D + Y DV+AS AFG VDS
Sbjct: 149 LNEMVPLISQACDLLLAHLK-RYAESGDAF---DIQRCYCNYTTDVVASVAFGTPVDSWQ 204
Query: 707 EENNQFYAMGKAASTFNFRQLLIFFGLASVPXLVKILRI--TLFQKEIKTFFRELI 868
+ F K F + ++ L+ +V + RI + E+ FF +LI
Sbjct: 205 APEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLI 260
>AK223466-1|BAD97186.1| 534|Homo sapiens thromboxane A synthase 1
(platelet, cytochrome P450, family 5, subfamily A) iso
protein.
Length = 534
Score = 69.7 bits (163), Expect = 1e-11
Identities = 62/236 (26%), Positives = 108/236 (45%), Gaps = 2/236 (0%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
A+S K G++ P PF GN+ ++ LY ++GR F ++
Sbjct: 36 AFSRLEKLGLRHPKPSPFIGNLTFFRQGFWESQMELRKLYGPLCGY-YLGRRMF----IV 90
Query: 347 IRDIELLKKITVKDFEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSSK 526
I + +++K++ V++F +F + + + S+ FLRD+ W+++R L AF+ K
Sbjct: 91 ISEPDMIKQVLVENFSNFTNR--MASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSPEK 148
Query: 527 MKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSIT 706
+ M+P I + + LK R E+G + D + Y DV+AS AFG VDS
Sbjct: 149 LNEMVPLISQACDLLLAHLK-RYAESGDAF---DIQRCYCNYTTDVVASVAFGTPVDSWQ 204
Query: 707 EENNQFYAMGKAASTFNFRQLLIFFGLASVPXLVKILRI--TLFQKEIKTFFRELI 868
+ F K F + ++ L+ +V + RI + E+ FF +LI
Sbjct: 205 APEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLI 260
>AF233619-1|AAF99273.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 68.5 bits (160), Expect = 3e-11
Identities = 61/236 (25%), Positives = 108/236 (45%), Gaps = 2/236 (0%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
A+S K G++ P PF GN+ ++ LY ++GR F ++
Sbjct: 36 AFSRLEKLGLRHPKPSPFIGNLTFFRQGFWESQMELRKLYGPLCGY-YLGRRMF----IV 90
Query: 347 IRDIELLKKITVKDFEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSSK 526
I + +++K++ V++F +F + + + S+ FLRD+ W+++R L AF+ K
Sbjct: 91 ISEPDMIKQVLVENFSNFTNR--MASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSPEK 148
Query: 527 MKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSIT 706
+ M+P I + + + LK R E+G + D + Y DV+AS FG VDS
Sbjct: 149 LNEMVPLISQACELLLAHLK-RYAESGDAF---DIQRCYCNYTTDVVASVPFGTPVDSWQ 204
Query: 707 EENNQFYAMGKAASTFNFRQLLIFFGLASVPXLVKILRI--TLFQKEIKTFFRELI 868
+ F K F + ++ L+ +V + RI + E+ FF +LI
Sbjct: 205 APEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLI 260
>AF233620-1|AAF99274.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 68.1 bits (159), Expect = 4e-11
Identities = 61/236 (25%), Positives = 108/236 (45%), Gaps = 2/236 (0%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
A+S K G++ P PF GN+ ++ LY ++GR F ++
Sbjct: 36 AFSRLEKLGLRHPKPSPFIGNLTFFRQGFWESQMELRKLYGPLCGY-YLGRRMF----IV 90
Query: 347 IRDIELLKKITVKDFEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSSK 526
I + +++K++ V++F +F + + + S+ FLRD+ W+++R L AF+ K
Sbjct: 91 ISEPDMIKQVLVENFSNFTNR--MASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSPEK 148
Query: 527 MKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSIT 706
+ M+P I + + LK R E+G + D + Y DV+AS FG VDS
Sbjct: 149 LNEMVPLISQACDLLLAHLK-RYAESGDAF---DIQRCYCNYTTDVVASVPFGTPVDSWQ 204
Query: 707 EENNQFYAMGKAASTFNFRQLLIFFGLASVPXLVKILRI--TLFQKEIKTFFRELI 868
+ F K F + ++ L+ +V + RI + + E+ FF +LI
Sbjct: 205 APEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPSKNRDELNGFFNKLI 260
>M80647-1|AAA60618.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 67.7 bits (158), Expect = 5e-11
Identities = 61/236 (25%), Positives = 107/236 (45%), Gaps = 2/236 (0%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
A+S K G++ P PF GN+ ++ LY ++GR F ++
Sbjct: 36 AFSRLEKLGLRHPKPSPFIGNLTFFRQGFWESQMELRKLYGPLCGY-YLGRRMF----IV 90
Query: 347 IRDIELLKKITVKDFEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSSK 526
I + +++K++ V++F +F + + + S+ FLRD+ W+++R L AF+ K
Sbjct: 91 ISEPDMIKQVLVENFSNFTNR--MASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSPEK 148
Query: 527 MKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSIT 706
+ M+P I + + LK R E+G + D + Y DV+AS FG VDS
Sbjct: 149 LNEMVPLISQACDLLLAHLK-RYAESGDAF---DIQRCYCNYTTDVVASVPFGTPVDSWQ 204
Query: 707 EENNQFYAMGKAASTFNFRQLLIFFGLASVPXLVKILRI--TLFQKEIKTFFRELI 868
+ F K F + ++ L+ +V + RI + E+ FF +LI
Sbjct: 205 APEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLI 260
>M80646-1|AAA60617.1| 460|Homo sapiens thromboxane synthase
protein.
Length = 460
Score = 67.7 bits (158), Expect = 5e-11
Identities = 61/236 (25%), Positives = 107/236 (45%), Gaps = 2/236 (0%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
A+S K G++ P PF GN+ ++ LY ++GR F ++
Sbjct: 36 AFSRLEKLGLRHPKPSPFIGNLTFFRQGFWESQMELRKLYGPLCGY-YLGRRMF----IV 90
Query: 347 IRDIELLKKITVKDFEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSSK 526
I + +++K++ V++F +F + + + S+ FLRD+ W+++R L AF+ K
Sbjct: 91 ISEPDMIKQVLVENFSNFTNR--MASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSPEK 148
Query: 527 MKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSIT 706
+ M+P I + + LK R E+G + D + Y DV+AS FG VDS
Sbjct: 149 LNEMVPLISQACDLLLAHLK-RYAESGDAF---DIQRCYCNYTTDVVASVPFGTPVDSWQ 204
Query: 707 EENNQFYAMGKAASTFNFRQLLIFFGLASVPXLVKILRI--TLFQKEIKTFFRELI 868
+ F K F + ++ L+ +V + RI + E+ FF +LI
Sbjct: 205 APEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLI 260
>AF233625-1|AAF99279.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 67.7 bits (158), Expect = 5e-11
Identities = 61/236 (25%), Positives = 107/236 (45%), Gaps = 2/236 (0%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
A+S K G++ P PF GN+ ++ LY ++GR F ++
Sbjct: 36 AFSRLEKLGLRHPKPSPFIGNLTFFRQGFWESQMELRKLYGPLCGY-YLGRRMF----IV 90
Query: 347 IRDIELLKKITVKDFEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSSK 526
I + +++K++ V++F +F + + + S+ FLRD+ W+++R L AF+ K
Sbjct: 91 ISEPDMIKQVLVENFSNFTNR--MASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSPEK 148
Query: 527 MKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSIT 706
+ M+P I + + LK R E+G + D + Y DV+AS FG VDS
Sbjct: 149 LNEMVPLISQACDLLLAHLK-RYAESGDAF---DIQRCYCNYTTDVVASVPFGTPVDSWQ 204
Query: 707 EENNQFYAMGKAASTFNFRQLLIFFGLASVPXLVKILRI--TLFQKEIKTFFRELI 868
+ F K F + ++ L+ +V + RI + E+ FF +LI
Sbjct: 205 APEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLI 260
>AF233624-1|AAF99278.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 67.7 bits (158), Expect = 5e-11
Identities = 61/236 (25%), Positives = 107/236 (45%), Gaps = 2/236 (0%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
A+S K G++ P PF GN+ ++ LY ++GR F ++
Sbjct: 36 AFSRLEKLGLRHPKPSPFIGNLTFFRQGFWESQMELRKLYGPLCGY-YLGRRMF----IV 90
Query: 347 IRDIELLKKITVKDFEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSSK 526
I + +++K++ V++F +F + + + S+ FLRD+ W+++R L AF+ K
Sbjct: 91 ISEPDMIKQVLVENFSNFTNR--MASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSPEK 148
Query: 527 MKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSIT 706
+ M+P I + + LK R E+G + D + Y DV+AS FG VDS
Sbjct: 149 LNEMVPLISQACDLLLAHLK-RYAESGDAF---DIQRCYCNYTTDVVASVPFGTPVDSWQ 204
Query: 707 EENNQFYAMGKAASTFNFRQLLIFFGLASVPXLVKILRI--TLFQKEIKTFFRELI 868
+ F K F + ++ L+ +V + RI + E+ FF +LI
Sbjct: 205 APEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLI 260
>AF233623-1|AAF99277.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 67.7 bits (158), Expect = 5e-11
Identities = 61/236 (25%), Positives = 107/236 (45%), Gaps = 2/236 (0%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
A+S K G++ P PF GN+ ++ LY ++GR F ++
Sbjct: 36 AFSRLEKLGLRHPKPSPFIGNLTFFRQGFWESQMELRKLYGPLCGY-YLGRRMF----IV 90
Query: 347 IRDIELLKKITVKDFEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSSK 526
I + +++K++ V++F +F + + + S+ FLRD+ W+++R L AF+ K
Sbjct: 91 ISEPDMIKQVLVENFSNFTNR--MASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSPEK 148
Query: 527 MKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSIT 706
+ M+P I + + LK R E+G + D + Y DV+AS FG VDS
Sbjct: 149 LNEMVPLISQACDLLLAHLK-RYAESGDAF---DIQRCYCNYTTDVVASVPFGTPVDSWQ 204
Query: 707 EENNQFYAMGKAASTFNFRQLLIFFGLASVPXLVKILRI--TLFQKEIKTFFRELI 868
+ F K F + ++ L+ +V + RI + E+ FF +LI
Sbjct: 205 APEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLI 260
>AF233622-1|AAF99276.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 67.7 bits (158), Expect = 5e-11
Identities = 61/236 (25%), Positives = 107/236 (45%), Gaps = 2/236 (0%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
A+S K G++ P PF GN+ ++ LY ++GR F ++
Sbjct: 36 AFSRLEKLGLRHPKPSPFIGNLTFFRQGFWESQMELRKLYGPLCGY-YLGRRMF----IV 90
Query: 347 IRDIELLKKITVKDFEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSSK 526
I + +++K++ V++F +F + + + S+ FLRD+ W+++R L AF+ K
Sbjct: 91 ISEPDMIKQVLVENFSNFTNR--MASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSPEK 148
Query: 527 MKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSIT 706
+ M+P I + + LK R E+G + D + Y DV+AS FG VDS
Sbjct: 149 LNEMVPLISQACDLLLAHLK-RYAESGDAF---DIQRCYCNYTTDVVASVPFGTPVDSWQ 204
Query: 707 EENNQFYAMGKAASTFNFRQLLIFFGLASVPXLVKILRI--TLFQKEIKTFFRELI 868
+ F K F + ++ L+ +V + RI + E+ FF +LI
Sbjct: 205 APEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLI 260
>AF233621-1|AAF99275.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 67.7 bits (158), Expect = 5e-11
Identities = 61/236 (25%), Positives = 107/236 (45%), Gaps = 2/236 (0%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
A+S K G++ P PF GN+ ++ LY ++GR F ++
Sbjct: 36 AFSRLEKLGLRHPKPSPFIGNLTFFRQGFWESQMELRKLYGPLCGY-YLGRRMF----IV 90
Query: 347 IRDIELLKKITVKDFEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSSK 526
I + +++K++ V++F +F + + + S+ FLRD+ W+++R L AF+ K
Sbjct: 91 ISEPDMIKQVLVENFSNFTNR--MASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSPEK 148
Query: 527 MKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSIT 706
+ M+P I + + LK R E+G + D + Y DV+AS FG VDS
Sbjct: 149 LNEMVPLISQACDLLLAHLK-RYAESGDAF---DIQRCYCNYTTDVVASVPFGTPVDSWQ 204
Query: 707 EENNQFYAMGKAASTFNFRQLLIFFGLASVPXLVKILRI--TLFQKEIKTFFRELI 868
+ F K F + ++ L+ +V + RI + E+ FF +LI
Sbjct: 205 APEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLI 260
>AF233618-1|AAF99272.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 67.7 bits (158), Expect = 5e-11
Identities = 61/236 (25%), Positives = 107/236 (45%), Gaps = 2/236 (0%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
A+S K G++ P PF GN+ ++ LY ++GR F ++
Sbjct: 36 AFSRLEKLGLRHPKPSPFIGNLTFFHQGFWESQMELRKLYGPLCGY-YLGRRMF----IV 90
Query: 347 IRDIELLKKITVKDFEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSSK 526
I + +++K++ V++F +F + + + S+ FLRD+ W+++R L AF+ K
Sbjct: 91 ISEPDMIKQVLVENFSNFTNR--MASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSPEK 148
Query: 527 MKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSIT 706
+ M+P I + + LK R E+G + D + Y DV+AS FG VDS
Sbjct: 149 LNEMVPLISQACDLLLAHLK-RYAESGDAF---DIQRCYCNYTTDVVASVPFGTPVDSWQ 204
Query: 707 EENNQFYAMGKAASTFNFRQLLIFFGLASVPXLVKILRI--TLFQKEIKTFFRELI 868
+ F K F + ++ L+ +V + RI + E+ FF +LI
Sbjct: 205 APEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLI 260
>AF233617-1|AAF99271.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 67.7 bits (158), Expect = 5e-11
Identities = 61/236 (25%), Positives = 107/236 (45%), Gaps = 2/236 (0%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
A+S K G++ P PF GN+ ++ LY ++GR F ++
Sbjct: 36 AFSRLEKLGLRHPKPSPFIGNLTFFRQGFWESQMELRKLYGPLCGY-YLGRRMF----IV 90
Query: 347 IRDIELLKKITVKDFEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSSK 526
I + +++K++ V++F +F + + + S+ FLRD+ W+++R L AF+ K
Sbjct: 91 ISEPDMIKQVLVENFSNFTNR--MASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSPEK 148
Query: 527 MKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSIT 706
+ M+P I + + LK R E+G + D + Y DV+AS FG VDS
Sbjct: 149 LNEMVPLISQACDLLLAHLK-RYAESGDAF---DIQRCYCNYTTDVVASVPFGTPVDSWQ 204
Query: 707 EENNQFYAMGKAASTFNFRQLLIFFGLASVPXLVKILRI--TLFQKEIKTFFRELI 868
+ F K F + ++ L+ +V + RI + E+ FF +LI
Sbjct: 205 APEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLI 260
>AF233616-1|AAF99270.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 67.7 bits (158), Expect = 5e-11
Identities = 61/236 (25%), Positives = 107/236 (45%), Gaps = 2/236 (0%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
A+S K G++ P PF GN+ ++ LY ++GR F ++
Sbjct: 36 AFSRLEKLGLRHPKPSPFIGNLTFFRQGFWESQMELRKLYGPLCGY-YLGRRMF----IV 90
Query: 347 IRDIELLKKITVKDFEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSSK 526
I + +++K++ V++F +F + + + S+ FLRD+ W+++R L AF+ K
Sbjct: 91 ISEPDMIKQVLVENFSNFTNR--MASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSPEK 148
Query: 527 MKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSIT 706
+ M+P I + + LK R E+G + D + Y DV+AS FG VDS
Sbjct: 149 LNEMVPLISQACDLLLAHLK-RYAESGDAF---DIQRCYCNYTTDVVASVPFGTPVDSWQ 204
Query: 707 EENNQFYAMGKAASTFNFRQLLIFFGLASVPXLVKILRI--TLFQKEIKTFFRELI 868
+ F K F + ++ L+ +V + RI + E+ FF +LI
Sbjct: 205 APEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLI 260
>AF233615-1|AAF99269.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 67.7 bits (158), Expect = 5e-11
Identities = 61/236 (25%), Positives = 107/236 (45%), Gaps = 2/236 (0%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
A+S K G++ P PF GN+ ++ LY ++GR F ++
Sbjct: 36 AFSRLEKLGLRHPKPSPFIGNLTFFRQGFWESQMELRKLYGPLCGY-YLGRRMF----IV 90
Query: 347 IRDIELLKKITVKDFEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSSK 526
I + +++K++ V++F +F + + + S+ FLRD+ W+++R L AF+ K
Sbjct: 91 ISEPDMIKQVLVENFSNFTNR--MASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSPEK 148
Query: 527 MKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSIT 706
+ M+P I + + LK R E+G + D + Y DV+AS FG VDS
Sbjct: 149 LNEMVPLISQACDLLLAHLK-RYAESGDAF---DIQRCYCNYTTDVVASVPFGTPVDSWQ 204
Query: 707 EENNQFYAMGKAASTFNFRQLLIFFGLASVPXLVKILRI--TLFQKEIKTFFRELI 868
+ F K F + ++ L+ +V + RI + E+ FF +LI
Sbjct: 205 APEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLI 260
>L36085-1|AAC01761.1| 441|Homo sapiens thromboxane A2 synthase
protein.
Length = 441
Score = 67.3 bits (157), Expect = 7e-11
Identities = 61/236 (25%), Positives = 107/236 (45%), Gaps = 2/236 (0%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
A+S K G++ P PF GN+ ++ LY ++GR F ++
Sbjct: 36 AFSRLEKLGLRHPKPSPFIGNLTFFRQGFWESQMELRKLYGPLCGY-YLGRRMF----IV 90
Query: 347 IRDIELLKKITVKDFEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSSK 526
I + +++K++ V++F +F + + + S+ FLRD+ W+++R L AF+ K
Sbjct: 91 ISEPDMIKQVLVENFSNFTNR--MASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSPEK 148
Query: 527 MKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSIT 706
+ M+P I + + LK R E+G + D + Y DV+AS FG VDS
Sbjct: 149 VNEMVPLISQACDLLLAHLK-RYAESGDAF---DIQRCYCNYTTDVVASVRFGTPVDSWQ 204
Query: 707 EENNQFYAMGKAASTFNFRQLLIFFGLASVPXLVKILRI--TLFQKEIKTFFRELI 868
+ F K F + ++ L+ +V + RI + E+ FF +LI
Sbjct: 205 APEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLI 260
>M74055-1|AAA36742.1| 229|Homo sapiens thromboxane synthase
protein.
Length = 229
Score = 64.5 bits (150), Expect = 5e-10
Identities = 56/219 (25%), Positives = 99/219 (45%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
A+S K G++ P PF GN+ ++ LY ++GR F ++
Sbjct: 20 AFSRLEKLGLRHPKPSPFIGNLTFFRQGFWESQMELRKLYGPLCGY-YLGRRMF----IV 74
Query: 347 IRDIELLKKITVKDFEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAFTSSK 526
I + +++K++ V++F +F + + + S+ FLRD+ W+++R L AF+ K
Sbjct: 75 ISEPDMIKQVLVQNFSNFTNR--MASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSPEK 132
Query: 527 MKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIASCAFGLKVDSIT 706
+ M+P I + + LK R E+G + D + Y DV+AS FG VDS
Sbjct: 133 LNEMVPLISQACDLLLAHLK-RYAESGDAF---DIQRCYCNYTTDVVASVPFGTPVDSWQ 188
Query: 707 EENNQFYAMGKAASTFNFRQLLIFFGLASVPXLVKILRI 823
+ F K F + ++ L+ +V + RI
Sbjct: 189 APEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPLARI 227
>AC004914-2|AAP21887.1| 311|Homo sapiens unknown protein.
Length = 311
Score = 64.1 bits (149), Expect = 6e-10
Identities = 50/187 (26%), Positives = 89/187 (47%), Gaps = 2/187 (1%)
Frame = +2
Query: 314 GRYEFLNPMVIIRDIELLKKITVKDFEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMR 493
G Y ++I + +++K++ V++F +F + + + S+ FLRD+ W+++R
Sbjct: 12 GYYLGRRMFIVISEPDMIKQVLVENFSNFTNR--MASGLEFKSVADSVLFLRDKRWEEVR 69
Query: 494 STLSPAFTSSKMKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIAS 673
L AF+ K+ M+P I + + + LK R E+G + D + Y DV+AS
Sbjct: 70 GALMSAFSPEKLNEMVPLISQACELLLAHLK-RYAESGDAF---DIQRCYCNYTTDVVAS 125
Query: 674 CAFGLKVDSITEENNQFYAMGKAASTFNFRQLLIFFGLASVPXLVKILRI--TLFQKEIK 847
AFG VDS + F K F + ++ L+ +V + RI + E+
Sbjct: 126 VAFGTPVDSWQAPEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELN 185
Query: 848 TFFRELI 868
FF +LI
Sbjct: 186 GFFNKLI 192
>BC014117-1|AAH14117.1| 466|Homo sapiens TBXAS1 protein protein.
Length = 466
Score = 63.3 bits (147), Expect = 1e-09
Identities = 50/187 (26%), Positives = 88/187 (47%), Gaps = 2/187 (1%)
Frame = +2
Query: 314 GRYEFLNPMVIIRDIELLKKITVKDFEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMR 493
G Y ++I + +++K++ V++F +F + + + S+ FLRD+ W+++R
Sbjct: 12 GYYLGRRMFIVISEPDMIKQVLVENFSNFTNR--MASGLEFKSVADSVLFLRDKRWEEVR 69
Query: 494 STLSPAFTSSKMKLMMPFIVEVGQQMNKALKQRIQEAGVGYVDIDSKDLTTRYANDVIAS 673
L AF+ K+ M+P I + + LK R E+G + D + Y DV+AS
Sbjct: 70 GALMSAFSPEKLNEMVPLISQACDLLLAHLK-RYAESGDAF---DIQRCYCNYTTDVVAS 125
Query: 674 CAFGLKVDSITEENNQFYAMGKAASTFNFRQLLIFFGLASVPXLVKILRI--TLFQKEIK 847
AFG VDS + F K F + ++ L+ +V + RI + E+
Sbjct: 126 VAFGTPVDSWQAPEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELN 185
Query: 848 TFFRELI 868
FF +LI
Sbjct: 186 GFFNKLI 192
>AJ563377-1|CAD91345.1| 353|Homo sapiens cytochrome P450 protein.
Length = 353
Score = 40.3 bits (90), Expect = 0.009
Identities = 22/76 (28%), Positives = 38/76 (50%), Gaps = 3/76 (3%)
Frame = +2
Query: 650 YANDVIASCAFGLKVDSITEENNQFYAMGKAASTFNFRQLLIFFGLASVPXLV---KILR 820
Y+ DVI S +FG+ +DS+ + F K F+F F + P L+ ++L
Sbjct: 29 YSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLD-PFFLSITVFPFLIPILEVLN 87
Query: 821 ITLFQKEIKTFFRELI 868
I +F +E+ F R+ +
Sbjct: 88 ICVFPREVTNFLRKSV 103
>AF280107-1|AAG32291.1| 106|Homo sapiens cytochrome P450
polypeptide 43 protein.
Length = 106
Score = 39.9 bits (89), Expect = 0.012
Identities = 23/74 (31%), Positives = 37/74 (50%)
Frame = +2
Query: 167 AYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMVI 346
++ LF K G+ G TPLPF G + + + +F Y G YE PM++
Sbjct: 29 SHKLFKKLGIPGPTPLPFLGTILFYLRGLWNFDRECNEKYG-----EMWGLYEGQQPMLV 83
Query: 347 IRDIELLKKITVKD 388
I D +++K + VK+
Sbjct: 84 IMDPDMIKTVLVKE 97
>AF280107-4|AAG32288.1| 106|Homo sapiens cytochrome P450
polypeptide 5 protein.
Length = 106
Score = 32.3 bits (70), Expect = 2.4
Identities = 20/75 (26%), Positives = 35/75 (46%)
Frame = +2
Query: 164 QAYSLFSKHGVKGFTPLPFFGNMGRIVIKMDHFSDHIQSLYDSFPEERFVGRYEFLNPMV 343
+ + LF + G+ G TPLP GN+ + F Y + G YE P++
Sbjct: 28 RTHGLFKRLGIPGPTPLPLLGNVLSYRQGLWKFDTECYKKYG-----KMWGTYEGQLPVL 82
Query: 344 IIRDIELLKKITVKD 388
I D ++++ + VK+
Sbjct: 83 AITDPDVIRTVLVKE 97
>BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family 4,
subfamily V, polypeptide 2 protein.
Length = 525
Score = 30.7 bits (66), Expect = 7.2
Identities = 32/146 (21%), Positives = 65/146 (44%), Gaps = 1/146 (0%)
Frame = +2
Query: 335 PMVIIRDIELLKKITVKDFEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAF 514
PMV + + E ++ I + +D ++ + K +P+ G L W+ R L+P F
Sbjct: 98 PMVALYNAENVEVILTSSKQ--ID-KSSMYKFLEPWLGLGLLTSTGNKWRSRRKMLTPTF 154
Query: 515 TSSKMKLMMPFIVEVGQQMNKALKQRI-QEAGVGYVDIDSKDLTTRYANDVIASCAFGLK 691
+ ++ + + E + K L++ I QEA + I T A D+I A G
Sbjct: 155 HFTILEDFLDIMNEQANILVKKLEKHINQEAFNCFFYI------TLCALDIICETAMGKN 208
Query: 692 VDSITEENNQFYAMGKAASTFNFRQL 769
+ + + +++++ S FR++
Sbjct: 209 IGAQSNDDSEYVRAVYRMSEMIFRRI 234
>AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2
protein.
Length = 525
Score = 30.7 bits (66), Expect = 7.2
Identities = 32/146 (21%), Positives = 65/146 (44%), Gaps = 1/146 (0%)
Frame = +2
Query: 335 PMVIIRDIELLKKITVKDFEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAF 514
PMV + + E ++ I + +D ++ + K +P+ G L W+ R L+P F
Sbjct: 98 PMVALYNAENVEVILTSSKQ--ID-KSSMYKFLEPWLGLGLLTSTGNKWRSRRKMLTPTF 154
Query: 515 TSSKMKLMMPFIVEVGQQMNKALKQRI-QEAGVGYVDIDSKDLTTRYANDVIASCAFGLK 691
+ ++ + + E + K L++ I QEA + I T A D+I A G
Sbjct: 155 HFTILEDFLDIMNEQANILVKKLEKHINQEAFNCFFYI------TLCALDIICETAMGKN 208
Query: 692 VDSITEENNQFYAMGKAASTFNFRQL 769
+ + + +++++ S FR++
Sbjct: 209 IGAQSNDDSEYVRAVYRMSEMIFRRI 234
>AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens
cDNA FLJ44509 fis, clone UTERU3001585, weakly similar
to Cytochrome P450 4c3 (EC 1.14.-.-). ).
Length = 503
Score = 30.7 bits (66), Expect = 7.2
Identities = 32/146 (21%), Positives = 65/146 (44%), Gaps = 1/146 (0%)
Frame = +2
Query: 335 PMVIIRDIELLKKITVKDFEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAF 514
PMV + + E ++ I + +D ++ + K +P+ G L W+ R L+P F
Sbjct: 76 PMVALYNAENVEVILTSSKQ--ID-KSSMYKFLEPWLGLGLLTSTGNKWRSRRKMLTPTF 132
Query: 515 TSSKMKLMMPFIVEVGQQMNKALKQRI-QEAGVGYVDIDSKDLTTRYANDVIASCAFGLK 691
+ ++ + + E + K L++ I QEA + I T A D+I A G
Sbjct: 133 HFTILEDFLDIMNEQANILVKKLEKHINQEAFNCFFYI------TLCALDIICETAMGKN 186
Query: 692 VDSITEENNQFYAMGKAASTFNFRQL 769
+ + + +++++ S FR++
Sbjct: 187 IGAQSNDDSEYVRAVYRMSEMIFRRI 212
>AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens
cDNA FLJ16007 fis, clone KIDNE2006580, weakly similar
to CYTOCHROME P450 4C1 (EC 1.14.14.1). ).
Length = 525
Score = 30.7 bits (66), Expect = 7.2
Identities = 32/146 (21%), Positives = 65/146 (44%), Gaps = 1/146 (0%)
Frame = +2
Query: 335 PMVIIRDIELLKKITVKDFEHFLDHRTIINKDTDPFFGRSLFFLRDQDWKDMRSTLSPAF 514
PMV + + E ++ I + +D ++ + K +P+ G L W+ R L+P F
Sbjct: 98 PMVALYNAENVEVILTSSKQ--ID-KSSMYKFLEPWLGLGLLTSTGNKWRSRRKMLTPTF 154
Query: 515 TSSKMKLMMPFIVEVGQQMNKALKQRI-QEAGVGYVDIDSKDLTTRYANDVIASCAFGLK 691
+ ++ + + E + K L++ I QEA + I T A D+I A G
Sbjct: 155 HFTILEDFLDIMNEQANILVKKLEKHINQEAFNCFFYI------TLCALDIICETAMGKN 208
Query: 692 VDSITEENNQFYAMGKAASTFNFRQL 769
+ + + +++++ S FR++
Sbjct: 209 IGAQSNDDSEYVRAVYRMSEMIFRRI 234
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 116,102,725
Number of Sequences: 237096
Number of extensions: 2502716
Number of successful extensions: 5084
Number of sequences better than 10.0: 62
Number of HSP's better than 10.0 without gapping: 4756
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4976
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11159604822
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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