Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P06_F_M18
(441 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q4S5H4 Cluster: Chromosome 3 SCAF14730, whole genome sh... 209 2e-53
UniRef50_Q96HU1 Cluster: RUN and TBC1 domain containing 3; n=34;... 209 2e-53
UniRef50_Q7Z709 Cluster: RUN and TBC1 domain-containing protein ... 209 2e-53
UniRef50_Q94222 Cluster: Putative uncharacterized protein; n=3; ... 116 3e-33
UniRef50_Q96C34 Cluster: RUN domain-containing protein 1; n=23; ... 60 2e-08
UniRef50_A7RKZ4 Cluster: Predicted protein; n=1; Nematostella ve... 49 4e-05
UniRef50_Q7QH55 Cluster: ENSANGP00000004077; n=2; Culicidae|Rep:... 48 7e-05
UniRef50_Q4SAV8 Cluster: Chromosome 3 SCAF14679, whole genome sh... 48 1e-04
UniRef50_Q54LN3 Cluster: Putative uncharacterized protein; n=1; ... 46 4e-04
UniRef50_UPI0000D575FF Cluster: PREDICTED: similar to RUN domain... 44 0.001
UniRef50_UPI000051A248 Cluster: PREDICTED: similar to RUN domain... 43 0.003
UniRef50_UPI00015B4A21 Cluster: PREDICTED: similar to RUN domain... 42 0.004
UniRef50_Q9W5C1 Cluster: CG3703-PA; n=3; Sophophora|Rep: CG3703-... 42 0.004
UniRef50_Q22585 Cluster: Putative uncharacterized protein; n=2; ... 42 0.004
UniRef50_UPI0000E48609 Cluster: PREDICTED: similar to RAB6 inter... 41 0.014
UniRef50_Q4SJ63 Cluster: Chromosome 4 SCAF14575, whole genome sh... 35 0.67
UniRef50_Q4RID4 Cluster: Chromosome 8 SCAF15044, whole genome sh... 34 1.2
UniRef50_Q8TI50 Cluster: TPR-domain containing protein; n=4; Met... 32 6.3
UniRef50_Q7F9R1 Cluster: OSJNBb0068N06.19 protein; n=2; Oryza sa... 31 8.3
>UniRef50_Q4S5H4 Cluster: Chromosome 3 SCAF14730, whole genome shotgun
sequence; n=3; Clupeocephala|Rep: Chromosome 3 SCAF14730,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 814
Score = 209 bits (511), Expect = 2e-53
Identities = 90/125 (72%), Positives = 108/125 (86%), Gaps = 1/125 (0%)
Frame = +3
Query: 3 VLTPEALLYXCVQAINLSHDNAHAQMDVKLRTLICMGLNEEALHLWLEVLCSCVDVVQKW 182
VLTPE LLY VQ++N+SHD AHAQMD+K R+L+C+GLNE+ LHLWLEVLCS V V+KW
Sbjct: 688 VLTPEELLYRAVQSVNMSHDLAHAQMDIKFRSLVCVGLNEQVLHLWLEVLCSSVAAVEKW 747
Query: 183 YHPWSFINSPGWVQIKCELRILSQFGFNLNPDWELPLKKDTQNQ-PLKEGVRDMLVKHHL 359
YHPWSF+ SPGWVQIKCELR+LS+F F+L+ D ELP KK+ + Q PLKEGV+DMLVKHHL
Sbjct: 748 YHPWSFLRSPGWVQIKCELRVLSKFAFSLSQDCELPEKKEEKEQRPLKEGVQDMLVKHHL 807
Query: 360 FSWDL 374
FSWD+
Sbjct: 808 FSWDI 812
>UniRef50_Q96HU1 Cluster: RUN and TBC1 domain containing 3; n=34;
Eumetazoa|Rep: RUN and TBC1 domain containing 3 - Homo
sapiens (Human)
Length = 749
Score = 209 bits (511), Expect = 2e-53
Identities = 90/124 (72%), Positives = 106/124 (85%)
Frame = +3
Query: 3 VLTPEALLYXCVQAINLSHDNAHAQMDVKLRTLICMGLNEEALHLWLEVLCSCVDVVQKW 182
VLTPE LLY VQ++N++HD HAQMDVKLR+LIC+GLNE+ LHLWLEVLCS + V+KW
Sbjct: 625 VLTPEELLYRAVQSVNVTHDAVHAQMDVKLRSLICVGLNEQVLHLWLEVLCSSLPTVEKW 684
Query: 183 YHPWSFINSPGWVQIKCELRILSQFGFNLNPDWELPLKKDTQNQPLKEGVRDMLVKHHLF 362
Y PWSF+ SPGWVQIKCELR+L F F+L+ DWELP K++ Q QPLKEGVRDMLVKHHLF
Sbjct: 685 YQPWSFLRSPGWVQIKCELRVLCCFAFSLSQDWELPAKREAQ-QPLKEGVRDMLVKHHLF 743
Query: 363 SWDL 374
SWD+
Sbjct: 744 SWDV 747
>UniRef50_Q7Z709 Cluster: RUN and TBC1 domain-containing protein 3;
n=11; Tetrapoda|Rep: RUN and TBC1 domain-containing
protein 3 - Homo sapiens (Human)
Length = 777
Score = 209 bits (511), Expect = 2e-53
Identities = 90/124 (72%), Positives = 106/124 (85%)
Frame = +3
Query: 3 VLTPEALLYXCVQAINLSHDNAHAQMDVKLRTLICMGLNEEALHLWLEVLCSCVDVVQKW 182
VLTPE LLY VQ++N++HD HAQMDVKLR+LIC+GLNE+ LHLWLEVLCS + V+KW
Sbjct: 653 VLTPEELLYRAVQSVNVTHDAVHAQMDVKLRSLICVGLNEQVLHLWLEVLCSSLPTVEKW 712
Query: 183 YHPWSFINSPGWVQIKCELRILSQFGFNLNPDWELPLKKDTQNQPLKEGVRDMLVKHHLF 362
Y PWSF+ SPGWVQIKCELR+L F F+L+ DWELP K++ Q QPLKEGVRDMLVKHHLF
Sbjct: 713 YQPWSFLRSPGWVQIKCELRVLCCFAFSLSQDWELPAKREAQ-QPLKEGVRDMLVKHHLF 771
Query: 363 SWDL 374
SWD+
Sbjct: 772 SWDV 775
>UniRef50_Q94222 Cluster: Putative uncharacterized protein; n=3;
Bilateria|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 826
Score = 116 bits (280), Expect(2) = 3e-33
Identities = 51/98 (52%), Positives = 70/98 (71%), Gaps = 3/98 (3%)
Frame = +3
Query: 3 VLTPEALLYXCVQAINLSHDNAHAQMDVKLRTLICMGLNEEALHLWLEVLCSCVD---VV 173
+LTPE LL+ VQ IN SH+ A DVKLR+L+ +G+NE+ +HLW ++LCS +
Sbjct: 670 ILTPEELLFRSVQLINDSHNAVSAHSDVKLRSLLVVGVNEQCIHLWFDLLCSATQHEHIR 729
Query: 174 QKWYHPWSFINSPGWVQIKCELRILSQFGFNLNPDWEL 287
K+YH W+FI SP W QIKC+LR+LSQF FNL+ +E+
Sbjct: 730 NKYYHSWAFIRSPAWRQIKCDLRLLSQFSFNLSMSFEI 767
Score = 46.8 bits (106), Expect(2) = 3e-33
Identities = 18/26 (69%), Positives = 21/26 (80%)
Frame = +3
Query: 297 KDTQNQPLKEGVRDMLVKHHLFSWDL 374
K +PLK+GV DML+KHHLFSWDL
Sbjct: 801 KQNGEEPLKQGVTDMLIKHHLFSWDL 826
>UniRef50_Q96C34 Cluster: RUN domain-containing protein 1; n=23;
Euteleostomi|Rep: RUN domain-containing protein 1 - Homo
sapiens (Human)
Length = 613
Score = 60.5 bits (140), Expect = 2e-08
Identities = 28/92 (30%), Positives = 46/92 (50%)
Frame = +3
Query: 3 VLTPEALLYXCVQAINLSHDNAHAQMDVKLRTLICMGLNEEALHLWLEVLCSCVDVVQKW 182
V+TP+ L + + HD D +L+ L+CM LNE+ L W+ ++C +++
Sbjct: 509 VVTPKQSLLTAIHMVLTEHDPFKRSADSELKALVCMALNEQRLVSWVNLICKSGSLIEPH 568
Query: 183 YHPWSFINSPGWVQIKCELRILSQFGFNLNPD 278
Y PWS++ G+ L LS F+L D
Sbjct: 569 YQPWSYMAHTGFESALNLLSRLSSLKFSLPVD 600
>UniRef50_A7RKZ4 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 376
Score = 49.2 bits (112), Expect = 4e-05
Identities = 24/91 (26%), Positives = 42/91 (46%)
Frame = +3
Query: 6 LTPEALLYXCVQAINLSHDNAHAQMDVKLRTLICMGLNEEALHLWLEVLCSCVDVVQKWY 185
+T + L + I +H+ MD ++L+C GLN++ L W ++ +V++ Y
Sbjct: 270 VTGKQTLLRTLHRIKSTHEPCRRSMDAMFKSLVCSGLNQKKLVQWCRIVMRTSCLVEEHY 329
Query: 186 HPWSFINSPGWVQIKCELRILSQFGFNLNPD 278
WS++ G + L L F F L D
Sbjct: 330 QSWSYVVKTGMSEAMGSLDRLQPFDFYLPED 360
>UniRef50_Q7QH55 Cluster: ENSANGP00000004077; n=2; Culicidae|Rep:
ENSANGP00000004077 - Anopheles gambiae str. PEST
Length = 628
Score = 48.4 bits (110), Expect = 7e-05
Identities = 24/91 (26%), Positives = 43/91 (47%)
Frame = +3
Query: 6 LTPEALLYXCVQAINLSHDNAHAQMDVKLRTLICMGLNEEALHLWLEVLCSCVDVVQKWY 185
L+ + L + +I H D + + +C GLN + L WL ++ C ++V Y
Sbjct: 524 LSNKQSLLSAIGSIIALHSPYKRSYDSQFKAFVCAGLNAQKLTQWLYLIFQCKELVSSHY 583
Query: 186 HPWSFINSPGWVQIKCELRILSQFGFNLNPD 278
WS++ + G+ L L+Q+ F+L D
Sbjct: 584 ASWSYVANTGFRDALKTLDCLTQYRFDLPVD 614
>UniRef50_Q4SAV8 Cluster: Chromosome 3 SCAF14679, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 3 SCAF14679, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 582
Score = 47.6 bits (108), Expect = 1e-04
Identities = 22/71 (30%), Positives = 35/71 (49%)
Frame = +3
Query: 6 LTPEALLYXCVQAINLSHDNAHAQMDVKLRTLICMGLNEEALHLWLEVLCSCVDVVQKWY 185
+TP+ L + ++ H D K + L+CM LNE+ L WL +LC +V Y
Sbjct: 501 VTPKQSLLWAIHSVLKEHGRYKRGPDTKFKALVCMALNEQRLVSWLNLLCKSGTLVDH-Y 559
Query: 186 HPWSFINSPGW 218
WS++ G+
Sbjct: 560 QAWSYMAQTGF 570
>UniRef50_Q54LN3 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 1368
Score = 46.0 bits (104), Expect = 4e-04
Identities = 27/90 (30%), Positives = 46/90 (51%), Gaps = 3/90 (3%)
Frame = +3
Query: 24 LYXCVQAINLSHDNAHAQMD--VKLRTLICMGLNEEALHLWLEVLCSCVDVVQKWYHPWS 197
L + IN + + A D +K RTLIC+GLN+ L W +L + + + ++HP +
Sbjct: 1096 LIQTINTINSFENISSAWKDPNIKFRTLICVGLNQHVLDQWFALLQTDTNGISHYFHPNA 1155
Query: 198 FINSPGWVQIKCE-LRILSQFGFNLNPDWE 284
INS ++ C+ + F L+ D+E
Sbjct: 1156 IINSLDHWRLFCQCFAPILNLPFKLSLDYE 1185
>UniRef50_UPI0000D575FF Cluster: PREDICTED: similar to RUN domain
containing 1; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to RUN domain containing 1 - Tribolium castaneum
Length = 524
Score = 44.0 bits (99), Expect = 0.001
Identities = 21/75 (28%), Positives = 33/75 (44%)
Frame = +3
Query: 54 SHDNAHAQMDVKLRTLICMGLNEEALHLWLEVLCSCVDVVQKWYHPWSFINSPGWVQIKC 233
+H D + IC LN L WL ++ C +V+ Y PWS++ G+
Sbjct: 436 THTPYKRSYDSHFKAFICAALNSNKLVSWLSLIFQCSQIVKLHYFPWSYVAKTGFQDSLK 495
Query: 234 ELRILSQFGFNLNPD 278
L L+ + F+L D
Sbjct: 496 SLDSLTGYKFDLPVD 510
>UniRef50_UPI000051A248 Cluster: PREDICTED: similar to RUN domain
containing 1; n=1; Apis mellifera|Rep: PREDICTED:
similar to RUN domain containing 1 - Apis mellifera
Length = 582
Score = 43.2 bits (97), Expect = 0.003
Identities = 23/92 (25%), Positives = 41/92 (44%)
Frame = +3
Query: 3 VLTPEALLYXCVQAINLSHDNAHAQMDVKLRTLICMGLNEEALHLWLEVLCSCVDVVQKW 182
V++ + L + I SH D + IC LN L +WL+++ C +++
Sbjct: 478 VVSSKQSLLTTIGNIIASHSPYKRSYDSHFKAFICASLNTNKLVIWLKLILQCQYLLENH 537
Query: 183 YHPWSFINSPGWVQIKCELRILSQFGFNLNPD 278
Y WS++ G+ L L+ + F+L D
Sbjct: 538 YTSWSYVIKTGFQDAFHTLDRLTSYKFDLPVD 569
>UniRef50_UPI00015B4A21 Cluster: PREDICTED: similar to RUN domain
containing 1; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to RUN domain containing 1 - Nasonia vitripennis
Length = 555
Score = 42.3 bits (95), Expect = 0.004
Identities = 20/74 (27%), Positives = 34/74 (45%)
Frame = +3
Query: 57 HDNAHAQMDVKLRTLICMGLNEEALHLWLEVLCSCVDVVQKWYHPWSFINSPGWVQIKCE 236
H D + IC LN L WL+++ C +++ +Y PWS++ G+
Sbjct: 469 HTPYKRSFDSNFKAFICAALNANKLVTWLKLILQCQYLLENYYMPWSYVIKTGFQDAFHT 528
Query: 237 LRILSQFGFNLNPD 278
L L++ F+L D
Sbjct: 529 LDKLTKHKFDLPID 542
>UniRef50_Q9W5C1 Cluster: CG3703-PA; n=3; Sophophora|Rep: CG3703-PA
- Drosophila melanogaster (Fruit fly)
Length = 711
Score = 42.3 bits (95), Expect = 0.004
Identities = 24/91 (26%), Positives = 40/91 (43%)
Frame = +3
Query: 6 LTPEALLYXCVQAINLSHDNAHAQMDVKLRTLICMGLNEEALHLWLEVLCSCVDVVQKWY 185
+T + L V I H + + +C GLN L WL ++ SC ++V +Y
Sbjct: 612 VTAKQSLLSAVGMILAMHRPYKRSNNAHFKAFVCAGLNSHLLVEWLNLILSCHELVDTYY 671
Query: 186 HPWSFINSPGWVQIKCELRILSQFGFNLNPD 278
S++ G+ + LS+F F+L D
Sbjct: 672 SADSYVARTGFRDSLRSIDALSRFDFDLPVD 702
>UniRef50_Q22585 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 634
Score = 42.3 bits (95), Expect = 0.004
Identities = 22/94 (23%), Positives = 42/94 (44%)
Frame = +3
Query: 6 LTPEALLYXCVQAINLSHDNAHAQMDVKLRTLICMGLNEEALHLWLEVLCSCVDVVQKWY 185
+T + +L ++ I +H D + + LNE+ L WL ++ VV+ Y
Sbjct: 531 ITSKQVLLTTIENIISTHARLKRSKDAHWKAFVSAALNEKKLPAWLRIIFRTRQVVEMCY 590
Query: 186 HPWSFINSPGWVQIKCELRILSQFGFNLNPDWEL 287
+ WS++ G ++ L L ++ +L D L
Sbjct: 591 NSWSYVARTGCEELYTLLEGLHKYSIHLPVDLAL 624
>UniRef50_UPI0000E48609 Cluster: PREDICTED: similar to RAB6
interacting protein 1; n=6; Deuterostomia|Rep: PREDICTED:
similar to RAB6 interacting protein 1 -
Strongylocentrotus purpuratus
Length = 1628
Score = 40.7 bits (91), Expect = 0.014
Identities = 21/64 (32%), Positives = 33/64 (51%), Gaps = 1/64 (1%)
Frame = +3
Query: 81 DVKLRTLICMGLNEEALHLWLEVLCSCVDVVQKWYHPWSFINSPGWVQIKCELRI-LSQF 257
D K + L+C+G+ + LH WL VL V + Y SF ++P + C L + L +F
Sbjct: 1212 DGKFQLLVCLGVRDHLLHQWLPVLAE-TPVTKNMYDECSFFHNPLHLDFLCSLLMQLDEF 1270
Query: 258 GFNL 269
+L
Sbjct: 1271 NISL 1274
>UniRef50_Q4SJ63 Cluster: Chromosome 4 SCAF14575, whole genome shotgun
sequence; n=5; Euteleostomi|Rep: Chromosome 4 SCAF14575,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 2096
Score = 35.1 bits (77), Expect = 0.67
Identities = 25/69 (36%), Positives = 34/69 (49%), Gaps = 6/69 (8%)
Frame = +3
Query: 84 VKLRTLICMGLNEEALHLWLEVLCSCVDVVQKWYHPWSFIN------SPGWVQIKCELRI 245
++LR I LN AL WL L S DVV YH W F++ P + ++ L+
Sbjct: 1502 MRLRAFIMGLLNLRALEFWLSHLHSQKDVVAANYHSWGFMSVSLGRCRPLFQELLLLLQP 1561
Query: 246 LSQFGFNLN 272
LS F+LN
Sbjct: 1562 LSVMPFDLN 1570
>UniRef50_Q4RID4 Cluster: Chromosome 8 SCAF15044, whole genome
shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 8
SCAF15044, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 463
Score = 34.3 bits (75), Expect = 1.2
Identities = 21/59 (35%), Positives = 31/59 (52%), Gaps = 6/59 (10%)
Frame = +3
Query: 114 LNEEALHLWLEVLCSCVDVVQKWYHPWSFIN------SPGWVQIKCELRILSQFGFNLN 272
LN + L WL L SC DV++ +Y P SF+ P + ++ L+ LS FNL+
Sbjct: 118 LNTKFLDFWLSHLHSCTDVLETYYQPASFMRLSLTACRPLFEELLLVLQPLSLLTFNLD 176
>UniRef50_Q8TI50 Cluster: TPR-domain containing protein; n=4;
Methanosarcina|Rep: TPR-domain containing protein -
Methanosarcina acetivorans
Length = 1079
Score = 31.9 bits (69), Expect = 6.3
Identities = 23/70 (32%), Positives = 31/70 (44%)
Frame = +3
Query: 6 LTPEALLYXCVQAINLSHDNAHAQMDVKLRTLICMGLNEEALHLWLEVLCSCVDVVQKWY 185
L EAL C + + LS + K L +G NEEAL + E+L D WY
Sbjct: 282 LYQEAL--TCYEFVLLSEPENLNTLQKKGFCLEQLGRNEEALQCYEEILTYSPDDADAWY 339
Query: 186 HPWSFINSPG 215
S +N+ G
Sbjct: 340 SKGSVLNAMG 349
>UniRef50_Q7F9R1 Cluster: OSJNBb0068N06.19 protein; n=2; Oryza
sativa|Rep: OSJNBb0068N06.19 protein - Oryza sativa
(Rice)
Length = 338
Score = 31.5 bits (68), Expect = 8.3
Identities = 15/44 (34%), Positives = 23/44 (52%)
Frame = -1
Query: 159 KNTILQATDVMLLHLSPYILMCAISHPSEHEHCHVINLLLGHXC 28
+ +L MLLHL P +L C+++ + HE H + L L C
Sbjct: 211 RRLVLPPLGGMLLHLLPGVLRCSLATHNFHELFHALLLFLNLPC 254
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 444,210,268
Number of Sequences: 1657284
Number of extensions: 8939339
Number of successful extensions: 18858
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 18454
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 18847
length of database: 575,637,011
effective HSP length: 93
effective length of database: 421,509,599
effective search space used: 22340008747
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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