Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P06_F_J22
(710 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450 monooxyge... 105 2e-22
BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family... 105 2e-22
AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family... 105 2e-22
AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein. 105 2e-22
AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2 pro... 105 2e-22
AF144566-1|AAD30164.1| 339|Homo sapiens cytochrome P450 epoxyge... 104 3e-22
AY220845-1|AAO49806.1| 516|Homo sapiens cytochrome P450 protein. 99 8e-21
EF122242-1|ABO41977.1| 321|Homo sapiens cytochrome P450 2F1 var... 100 1e-20
BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family... 99 2e-20
AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6 pro... 97 4e-20
EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1 var... 96 1e-19
M29873-1|AAA52143.1| 377|Homo sapiens CYP2B protein. 96 1e-19
BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family... 96 1e-19
BC041174-1|AAH41174.1| 377|Homo sapiens CYP2B7P1 protein protein. 96 1e-19
AK223113-1|BAD96833.1| 512|Homo sapiens cytochrome P450, family... 96 1e-19
X04300-1|CAA27843.1| 512|Homo sapiens P-450 c protein. 95 2e-19
X02612-1|CAA26458.1| 512|Homo sapiens cytochrome P(1)-450 protein. 95 2e-19
M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein. 95 2e-19
EF094025-1|ABK41999.1| 512|Homo sapiens cytochrome P450, family... 95 2e-19
DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family... 95 2e-19
BC023019-1|AAH23019.1| 512|Homo sapiens cytochrome P450, family... 95 2e-19
AF253322-1|AAK25727.1| 512|Homo sapiens cytochrome P450 protein. 95 2e-19
AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein. 95 2e-19
K03191-1|AAA52139.1| 512|Homo sapiens CYP1A1 protein. 95 2e-19
AY871801-1|AAX62803.1| 483|Homo sapiens cytochrome P450 family ... 95 2e-19
BC109056-1|AAI09057.1| 320|Homo sapiens CYP2F1 protein protein. 94 4e-19
DQ282158-1|ABB77906.1| 497|Homo sapiens cytochrome P450 2D6 pro... 93 7e-19
DQ282157-1|ABB77905.1| 497|Homo sapiens cytochrome P450 2D6 pro... 93 7e-19
DQ282153-1|ABB77901.1| 497|Homo sapiens cytochrome P450 2D6 pro... 93 7e-19
X08006-1|CAA30807.1| 497|Homo sapiens cytochrome P450 db1 protein. 93 9e-19
M33388-1|AAA53500.1| 497|Homo sapiens cytochrome P450 IID6 prot... 93 9e-19
M20403-1|AAA52153.1| 497|Homo sapiens CYP2D protein. 93 9e-19
DQ282160-1|ABB77908.1| 497|Homo sapiens cytochrome P450 2D6 pro... 93 9e-19
DQ282159-1|ABB77907.1| 497|Homo sapiens cytochrome P450 2D6 pro... 93 9e-19
DQ282156-1|ABB77904.1| 497|Homo sapiens cytochrome P450 2D6 pro... 93 9e-19
DQ282151-1|ABB77899.1| 496|Homo sapiens cytochrome P450 2D6 pro... 93 9e-19
DQ282147-1|ABB77898.1| 497|Homo sapiens cytochrome P450 2D6 pro... 93 9e-19
DQ282146-1|ABB77897.1| 497|Homo sapiens cytochrome P450 2D6 pro... 93 9e-19
DQ282145-1|ABB77896.1| 497|Homo sapiens cytochrome P450 2D6 pro... 93 9e-19
DQ282144-1|ABB77895.1| 497|Homo sapiens cytochrome P450 2D6 pro... 93 9e-19
BC126858-1|AAI26859.1| 497|Homo sapiens cytochrome P450, family... 93 9e-19
BC106758-1|AAI06759.1| 497|Homo sapiens cytochrome P450, family... 93 9e-19
BC075024-1|AAH75024.1| 497|Homo sapiens cytochrome P450, family... 93 9e-19
BC075023-1|AAH75023.1| 497|Homo sapiens cytochrome P450, family... 93 9e-19
BC067432-1|AAH67432.1| 497|Homo sapiens cytochrome P450, family... 93 9e-19
AY545216-1|AAS55001.1| 497|Homo sapiens cytochrome P4502D6 prot... 93 9e-19
AK223108-1|BAD96828.1| 512|Homo sapiens cytochrome P450, family... 93 9e-19
DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6 pro... 93 1e-18
DQ282155-1|ABB77903.1| 497|Homo sapiens cytochrome P450 2D6 pro... 91 3e-18
AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1 pro... 91 5e-18
J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein. 90 8e-18
DQ282152-1|ABB77900.1| 497|Homo sapiens cytochrome P450 2D6 pro... 90 8e-18
DQ211354-2|ABB01372.1| 497|Homo sapiens cytochrome P450 2D6 pro... 90 8e-18
DQ211353-2|ABB01371.1| 497|Homo sapiens cytochrome P450 2D6 pro... 90 8e-18
DQ211353-1|ABB01370.1| 497|Homo sapiens cytochrome P450 2D6 pro... 90 8e-18
AY310359-1|AAQ76692.1| 484|Homo sapiens cytochrome P450 1A1 var... 89 1e-17
AM236046-1|CAJ84703.1| 229|Homo sapiens cytochrome P450 1A1 pro... 89 1e-17
X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mR... 88 3e-17
X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for ... 88 3e-17
U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein. 88 3e-17
BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family... 88 3e-17
M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein. 87 4e-17
DQ282162-1|ABB77909.1| 500|Homo sapiens cytochrome P450 2D6 pro... 87 4e-17
M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein. 87 6e-17
BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family... 87 6e-17
BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family... 87 6e-17
BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family... 87 6e-17
AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6 pro... 87 6e-17
S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein. 87 8e-17
M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein. 87 8e-17
M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein. 87 8e-17
L16880-1|AAD13466.1| 273|Homo sapiens cytochrome P-450 2C protein. 87 8e-17
D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein. 87 8e-17
BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family... 87 8e-17
AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family... 87 8e-17
AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family... 87 8e-17
AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family... 87 8e-17
M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein. 86 1e-16
AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13 va... 86 1e-16
Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein. 85 2e-16
U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein. 85 2e-16
M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein. 85 2e-16
M17398-1|AAA35740.1| 393|Homo sapiens protein ( Human cytochrom... 85 2e-16
M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrom... 85 2e-16
AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family... 85 2e-16
AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family... 85 2e-16
AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family... 85 2e-16
AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family... 85 2e-16
AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family... 85 2e-16
BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family... 85 2e-16
BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family... 85 2e-16
AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13 va... 85 2e-16
AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13 va... 85 2e-16
AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13 va... 85 2e-16
AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13 va... 85 2e-16
AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13 pr... 85 2e-16
U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein. 85 3e-16
M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein. 85 3e-16
M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein. 84 4e-16
L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18 prot... 84 4e-16
BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein. 84 4e-16
BC096259-1|AAH96259.1| 443|Homo sapiens CYP2C18 protein protein. 84 4e-16
BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family... 84 4e-16
BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family... 84 4e-16
BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family... 84 4e-16
AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family... 84 4e-16
AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family... 83 1e-15
J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrom... 82 2e-15
J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrom... 82 2e-15
DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family... 82 2e-15
DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1 pro... 82 2e-15
AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family... 82 2e-15
AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1 pro... 82 2e-15
BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family... 81 3e-15
AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1 pro... 81 3e-15
BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family... 80 9e-15
S63426-1|ABB76283.1| 214|Homo sapiens (S)-mephenytoin hydroxyla... 79 2e-14
AM233520-1|CAJ80723.1| 189|Homo sapiens cytochrome P450 1A1 pro... 79 2e-14
AM233519-1|CAJ80722.1| 189|Homo sapiens cytochrome P450 1A1 pro... 79 2e-14
BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family... 78 3e-14
AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein. 78 3e-14
BC070317-1|AAH70317.1| 162|Homo sapiens CYP2C9 protein protein. 77 5e-14
BC020754-1|AAH20754.1| 162|Homo sapiens CYP2C9 protein protein. 77 5e-14
L39098-1|AAL31347.1| 160|Homo sapiens S-mephenytoin 4-hydroxyla... 77 6e-14
BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family... 76 1e-13
BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family... 76 1e-13
AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1 pro... 76 1e-13
Z00036-1|CAA77335.1| 515|Homo sapiens protein ( Human mRNA for ... 74 4e-13
M55053-1|AAA52146.1| 515|Homo sapiens cytochrome P3-450 protein. 74 4e-13
M31667-1|AAA52163.1| 515|Homo sapiens CYP1A2 protein. 74 4e-13
DQ022432-1|AAY26399.1| 516|Homo sapiens cytochrome P450, family... 74 4e-13
BC067429-1|AAH67429.1| 516|Homo sapiens cytochrome P450, family... 74 4e-13
BC067428-1|AAH67428.1| 516|Homo sapiens cytochrome P450, family... 74 4e-13
BC067426-1|AAH67426.1| 516|Homo sapiens cytochrome P450, family... 74 4e-13
BC067425-1|AAH67425.1| 516|Homo sapiens cytochrome P450, family... 74 4e-13
BC067424-1|AAH67424.1| 516|Homo sapiens cytochrome P450, family... 74 4e-13
AF253322-2|AAK25728.1| 516|Homo sapiens cytochrome P450 protein. 74 4e-13
AF182274-1|AAF13599.1| 516|Homo sapiens cytochrome P450-1A2 pro... 73 1e-12
L00389-1|AAA35738.1| 516|Homo sapiens protein ( Human cytochrom... 72 2e-12
BC067427-1|AAH67427.1| 516|Homo sapiens cytochrome P450, family... 71 3e-12
AB209492-1|BAD92729.1| 566|Homo sapiens Debrisoquine 4-hydroxyl... 60 7e-12
X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is ... 70 7e-12
BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family... 69 2e-11
AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein. 69 2e-11
AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens ... 69 2e-11
AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1 pro... 69 2e-11
BC025761-1|AAH25761.2| 490|Homo sapiens cytochrome P450, family... 68 3e-11
L07093-1|AAA36660.1| 468|Homo sapiens cytochrome P450 protein. 67 5e-11
M33189-1|AAA35737.1| 500|Homo sapiens protein ( Human debrisoqu... 59 1e-08
M24499-1|AAA36403.1| 373|Homo sapiens cytochrome P450db1 protein. 58 4e-08
U56438-1|AAC50809.1| 543|Homo sapiens dioxin-inducible cytochro... 54 7e-07
U03688-1|AAA19567.1| 543|Homo sapiens cytochrome P450 protein. 54 7e-07
DQ359216-1|ABC95161.1| 347|Homo sapiens dioxin-inducible cytoch... 54 7e-07
BT019979-1|AAV38782.1| 543|Homo sapiens cytochrome P450, family... 54 7e-07
BC012049-1|AAH12049.1| 543|Homo sapiens cytochrome P450, family... 54 7e-07
AY393998-1|AAQ87875.1| 543|Homo sapiens cytochrome P450, family... 54 7e-07
AF450132-1|AAM50512.1| 543|Homo sapiens cytochrome P450 CYP1B1 ... 54 7e-07
AC009229-2|AAY15039.1| 543|Homo sapiens unknown protein. 54 7e-07
BT020001-1|AAV38804.1| 543|Homo sapiens cytochrome P450, family... 53 1e-06
M21940-1|AAA52159.1| 383|Homo sapiens CYP2C protein. 52 3e-06
AK000366-1|BAA91114.1| 408|Homo sapiens protein ( Homo sapiens ... 52 3e-06
M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein. 51 5e-06
M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein. 51 5e-06
M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein. 50 6e-06
DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family... 50 6e-06
BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family... 50 6e-06
BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family... 50 6e-06
BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family... 50 6e-06
AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family... 50 6e-06
M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein. 50 8e-06
BC109084-1|AAI09085.1| 448|Homo sapiens CYP24A1 protein protein. 47 8e-05
BC109083-1|AAI09084.1| 448|Homo sapiens CYP24A1 protein protein. 47 8e-05
AL138805-3|CAM27343.1| 448|Homo sapiens cytochrome P450, family... 47 8e-05
AL138805-2|CAB91829.1| 514|Homo sapiens cytochrome P450, family... 47 8e-05
L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3 ... 46 1e-04
CR456430-1|CAG30316.1| 446|Homo sapiens CYP2D6 protein. 46 2e-04
BC106757-1|AAI06758.1| 446|Homo sapiens cytochrome P450, family... 46 2e-04
BC066877-1|AAH66877.1| 446|Homo sapiens CYP2D6 protein protein. 46 2e-04
AY513607-1|AAR90938.1| 100|Homo sapiens truncated cytochrome P4... 45 2e-04
J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3 prot... 45 3e-04
DQ680079-1|ABG25922.1| 347|Homo sapiens truncated cytochrome P4... 45 3e-04
BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family... 45 3e-04
AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein. 45 3e-04
AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family... 44 4e-04
DQ211355-2|ABB01373.1| 117|Homo sapiens cytochrome P450 2D6 pro... 42 0.002
J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipin... 42 0.002
DQ372705-1|ABD16216.1| 150|Homo sapiens mutant cytochrome p450 ... 42 0.003
AF280107-4|AAG32288.1| 106|Homo sapiens cytochrome P450 polypep... 42 0.003
X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for ... 41 0.004
M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA... 41 0.004
M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrom... 41 0.004
DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family ... 41 0.004
DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family... 41 0.004
BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfam... 41 0.004
BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family... 41 0.004
AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein. 41 0.004
AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450 polypep... 41 0.004
AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4 p... 41 0.004
AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4 pro... 41 0.004
AF171066-1|AAG43404.1| 112|Homo sapiens CYP1B1 variant protein. 39 0.015
BC012027-1|AAH12027.1| 168|Homo sapiens CYP2U1 protein protein. 38 0.035
AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43... 38 0.047
AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43... 38 0.047
AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfami... 38 0.047
AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43... 38 0.047
AF280111-1|AAG33012.1| 250|Homo sapiens cytochrome P450 subfami... 38 0.047
AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfami... 38 0.047
AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfami... 38 0.047
AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfami... 38 0.047
AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein. 38 0.047
AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein. 38 0.047
M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver glu... 37 0.082
D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein. 37 0.082
BC022539-1|AAH22539.1| 500|Homo sapiens cytochrome P450, family... 37 0.082
AF094480-1|AAD41244.1| 500|Homo sapiens cholesterol 24-hydroxyl... 37 0.082
X54807-1|CAA38578.1| 56|Homo sapiens unspecific monooxygenase ... 36 0.19
M61858-1|AAA52145.1| 370|Homo sapiens CYP2C17 protein. 36 0.19
AF280107-1|AAG32291.1| 106|Homo sapiens cytochrome P450 polypep... 36 0.19
BX538127-1|CAD98029.1| 310|Homo sapiens hypothetical protein pr... 34 0.44
AL512656-1|CAI15290.1| 488|Homo sapiens annexin A7 protein. 34 0.44
AL353731-3|CAI52484.1| 488|Homo sapiens annexin A7 protein. 34 0.44
X58906-1|CAA41709.1| 495|Homo sapiens steroid 21-monooxygenase ... 32 2.3
X58904-1|CAA41707.1| 371|Homo sapiens steroid 21-monooxygenase ... 32 2.3
X58902-1|CAA41706.1| 372|Homo sapiens steroid 21-monooxygenase ... 32 2.3
X58900-1|CAA41704.1| 372|Homo sapiens steroid 21-monooxygenase ... 32 2.3
M28548-1|AAA52065.1| 495|Homo sapiens protein ( Human mutant 21... 32 2.3
M26856-1|AAA52064.1| 495|Homo sapiens protein ( Human 21-hydrox... 32 2.3
M21550-1|AAA52063.1| 495|Homo sapiens CYP21 protein. 32 2.3
M13936-1|AAA59695.1| 494|Homo sapiens CYP21P protein. 32 2.3
M12792-1|AAB59440.1| 494|Homo sapiens steroid 21-hydroxylase pr... 32 2.3
D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa pro... 32 2.3
BX679671-8|CAM26070.1| 494|Homo sapiens cytochrome P450, family... 32 2.3
BC125182-1|AAI25183.1| 494|Homo sapiens cytochrome P450, family... 32 2.3
BC125181-1|AAI25182.1| 495|Homo sapiens cytochrome P450, family... 32 2.3
BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family... 32 2.3
AM183951-1|CAJ75805.1| 494|Homo sapiens steroid 21-hydroxylase,... 32 2.3
AM183950-1|CAJ75804.1| 494|Homo sapiens steroid 21-hydroxylase,... 32 2.3
AM183949-1|CAJ75803.1| 494|Homo sapiens steroid 21-hydroxylase,... 32 2.3
AM183948-1|CAJ75802.1| 494|Homo sapiens steroid 21-hydroxylase ... 32 2.3
AM183947-1|CAJ75801.1| 494|Homo sapiens steroid 21-hydroxylase,... 32 2.3
AM086565-1|CAJ31104.1| 494|Homo sapiens steroid 21-hydroxylase,... 32 2.3
AL929593-1|CAI41779.1| 495|Homo sapiens cytochrome P450, family... 32 2.3
AL662849-18|CAI17479.1| 495|Homo sapiens cytochrome P450, famil... 32 2.3
AL645922-24|CAI41754.1| 495|Homo sapiens cytochrome P450, famil... 32 2.3
AL049547-7|CAB89301.1| 495|Homo sapiens dJ34F7.3 (cytochrome P4... 32 2.3
AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant... 32 2.3
AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450 polypep... 32 2.3
AF019413-2|AAB67982.1| 495|Homo sapiens cytochrome P450 21-hydr... 32 2.3
X56452-1|CAA39833.1| 56|Homo sapiens unspecific monooxygenase ... 31 3.1
AF081569-1|AAD25924.1| 52|Homo sapiens cytochrome P450 protein. 31 3.1
AM183946-1|CAJ75800.1| 494|Homo sapiens steroid 21-hydroxylase,... 31 4.1
BC001964-1|AAH01964.1| 415|Homo sapiens acyl-Coenzyme A dehydro... 25 7.0
AK000359-1|BAA91109.1| 415|Homo sapiens protein ( Homo sapiens ... 25 7.0
AF260689-1|AAF97922.1| 415|Homo sapiens acyl-CoA dehydrogenase ... 25 7.0
AF126245-1|AAF12736.1| 415|Homo sapiens acyl-Coenzyme A dehydro... 25 7.0
AM183945-1|CAJ75799.1| 494|Homo sapiens steroid 21-hydroxylase,... 30 7.1
AK074640-1|BAC11107.1| 288|Homo sapiens protein ( Homo sapiens ... 25 7.2
X58898-1|CAA41702.1| 371|Homo sapiens steroid 21-monooxygenase ... 30 9.4
AM086564-1|CAJ31103.1| 494|Homo sapiens steroid 21-hydroxylase,... 30 9.4
>U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450
monooxygenase CYP2J2 protein.
Length = 502
Score = 105 bits (251), Expect = 2e-22
Identities = 69/214 (32%), Positives = 106/214 (49%), Gaps = 4/214 (1%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 188
+R R YPPGP LP +GN V F+ HL Q + +KYGNL L LG I+ V+
Sbjct: 36 KRRRPKNYPPGPWRLPFLGNFFLV-----DFEQSHLEVQLFVKKYGNLFSLELGDISAVL 90
Query: 189 VTGIELIRE--VSNREVFEGRPDGFFYTMRS-FGKKLGLVFSDGPTWHRTRRFVLKYLKN 359
+TG+ LI+E + + F RP MR KK GL+ S G W RRF L L+N
Sbjct: 91 ITGLPLIKEALIHMDQNFGNRP---VTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRN 147
Query: 360 FGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 539
FG + + I EE + L + + G+P + + + NI+ + G+R++ D
Sbjct: 148 FGLGKKSLEERIQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQDSW 207
Query: 540 LKKLCSLVMRLFKL-XDMSGGILNFLPFLXHFVP 638
++L L+ + L + + N P++ F+P
Sbjct: 208 FQQLLKLLDEVTYLEASKTCQLYNVFPWIMKFLP 241
>BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 105 bits (251), Expect = 2e-22
Identities = 69/214 (32%), Positives = 106/214 (49%), Gaps = 4/214 (1%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 188
+R R YPPGP LP +GN V F+ HL Q + +KYGNL L LG I+ V+
Sbjct: 36 KRRRPKNYPPGPWRLPFLGNFFLV-----DFEQSHLEVQLFVKKYGNLFSLELGDISAVL 90
Query: 189 VTGIELIRE--VSNREVFEGRPDGFFYTMRS-FGKKLGLVFSDGPTWHRTRRFVLKYLKN 359
+TG+ LI+E + + F RP MR KK GL+ S G W RRF L L+N
Sbjct: 91 ITGLPLIKEALIHMDQNFGNRP---VTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRN 147
Query: 360 FGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 539
FG + + I EE + L + + G+P + + + NI+ + G+R++ D
Sbjct: 148 FGLGKKSLEERIQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQDSW 207
Query: 540 LKKLCSLVMRLFKL-XDMSGGILNFLPFLXHFVP 638
++L L+ + L + + N P++ F+P
Sbjct: 208 FQQLLKLLDEVTYLEASKTCQLYNVFPWIMKFLP 241
>AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 105 bits (251), Expect = 2e-22
Identities = 69/214 (32%), Positives = 106/214 (49%), Gaps = 4/214 (1%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 188
+R R YPPGP LP +GN V F+ HL Q + +KYGNL L LG I+ V+
Sbjct: 36 KRRRPKNYPPGPWRLPFLGNFFLV-----DFEQSHLEVQLFVKKYGNLFSLELGDISAVL 90
Query: 189 VTGIELIRE--VSNREVFEGRPDGFFYTMRS-FGKKLGLVFSDGPTWHRTRRFVLKYLKN 359
+TG+ LI+E + + F RP MR KK GL+ S G W RRF L L+N
Sbjct: 91 ITGLPLIKEALIHMDQNFGNRP---VTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRN 147
Query: 360 FGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 539
FG + + I EE + L + + G+P + + + NI+ + G+R++ D
Sbjct: 148 FGLGKKSLEERIQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQDSW 207
Query: 540 LKKLCSLVMRLFKL-XDMSGGILNFLPFLXHFVP 638
++L L+ + L + + N P++ F+P
Sbjct: 208 FQQLLKLLDEVTYLEASKTCQLYNVFPWIMKFLP 241
>AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein.
Length = 502
Score = 105 bits (251), Expect = 2e-22
Identities = 69/214 (32%), Positives = 106/214 (49%), Gaps = 4/214 (1%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 188
+R R YPPGP LP +GN V F+ HL Q + +KYGNL L LG I+ V+
Sbjct: 36 KRRRPKNYPPGPWRLPFLGNFFLV-----DFEQSHLEVQLFVKKYGNLFSLELGDISAVL 90
Query: 189 VTGIELIRE--VSNREVFEGRPDGFFYTMRS-FGKKLGLVFSDGPTWHRTRRFVLKYLKN 359
+TG+ LI+E + + F RP MR KK GL+ S G W RRF L L+N
Sbjct: 91 ITGLPLIKEALIHMDQNFGNRP---VTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRN 147
Query: 360 FGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 539
FG + + I EE + L + + G+P + + + NI+ + G+R++ D
Sbjct: 148 FGLGKKSLEERIQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQDSW 207
Query: 540 LKKLCSLVMRLFKL-XDMSGGILNFLPFLXHFVP 638
++L L+ + L + + N P++ F+P
Sbjct: 208 FQQLLKLLDEVTYLEASKTCQLYNVFPWIMKFLP 241
>AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2
protein.
Length = 502
Score = 105 bits (251), Expect = 2e-22
Identities = 69/214 (32%), Positives = 106/214 (49%), Gaps = 4/214 (1%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 188
+R R YPPGP LP +GN V F+ HL Q + +KYGNL L LG I+ V+
Sbjct: 36 KRRRPKNYPPGPWRLPFLGNFFLV-----DFEQSHLEVQLFVKKYGNLFSLELGDISAVL 90
Query: 189 VTGIELIRE--VSNREVFEGRPDGFFYTMRS-FGKKLGLVFSDGPTWHRTRRFVLKYLKN 359
+TG+ LI+E + + F RP MR KK GL+ S G W RRF L L+N
Sbjct: 91 ITGLPLIKEALIHMDQNFGNRP---VTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRN 147
Query: 360 FGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 539
FG + + I EE + L + + G+P + + + NI+ + G+R++ D
Sbjct: 148 FGLGKKSLEERIQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQDSW 207
Query: 540 LKKLCSLVMRLFKL-XDMSGGILNFLPFLXHFVP 638
++L L+ + L + + N P++ F+P
Sbjct: 208 FQQLLKLLDEVTYLEASKTCQLYNVFPWIMKFLP 241
>AF144566-1|AAD30164.1| 339|Homo sapiens cytochrome P450
epoxygenase protein.
Length = 339
Score = 104 bits (250), Expect = 3e-22
Identities = 69/214 (32%), Positives = 106/214 (49%), Gaps = 4/214 (1%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 188
+R R YPPGP LP +GN V F+ HL Q + +KYGNL L LG I+ V+
Sbjct: 5 KRRRPKNYPPGPWRLPFLGNFFLV-----DFEQSHLEVQLFVKKYGNLFSLELGDISAVL 59
Query: 189 VTGIELIRE--VSNREVFEGRPDGFFYTMRS-FGKKLGLVFSDGPTWHRTRRFVLKYLKN 359
+TG+ LI+E + + F RP MR KK GL+ S G W RRF L L+N
Sbjct: 60 ITGLPLIKEALIHMDQNFGNRP---VTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRN 116
Query: 360 FGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 539
FG + + I EE + L + + G+P + + + NI+ + G+R++ D
Sbjct: 117 FGLGKKGLEERIQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQDSW 176
Query: 540 LKKLCSLVMRLFKL-XDMSGGILNFLPFLXHFVP 638
++L L+ + L + + N P++ F+P
Sbjct: 177 FQQLLKLLDEVTYLEASKTCQLYNVFPWIMKFLP 210
>AY220845-1|AAO49806.1| 516|Homo sapiens cytochrome P450 protein.
Length = 516
Score = 99 bits (238), Expect = 8e-21
Identities = 65/212 (30%), Positives = 103/212 (48%), Gaps = 5/212 (2%)
Frame = +3
Query: 30 YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELI 209
YPPGP PLP +GNLL V +++ + C + +++G++ L+L VVV+ G+ +
Sbjct: 33 YPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFNLQLAWTPVVVLNGLAAV 87
Query: 210 RE--VSNREVFEGRPDGFFYTMRSFG-KKLGLVFSD-GPTWHRTRRFVLKYLKNFGYNSR 377
RE V+ E RP Y + FG + G++ S GP W RRF + L+N G +
Sbjct: 88 REAMVTRGEDTADRPPAPIYQVLGFGPRSQGVILSRYGPAWREQRRFSVSTLRNLGLGKK 147
Query: 378 FMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCS 557
+ ++ EE L AG P N + + N++ L G+R++ D R +L
Sbjct: 148 SLEQWVTEEAACLCAAFADQAGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLD 207
Query: 558 LVMR-LFKLXDMSGGILNFLPFLXHFVPRLIG 650
L L + +LN +P L H +P L G
Sbjct: 208 LAQEGLKEESGFLREVLNAVPVLPH-IPALAG 238
>EF122242-1|ABO41977.1| 321|Homo sapiens cytochrome P450 2F1
variant protein.
Length = 321
Score = 99.5 bits (237), Expect = 1e-20
Identities = 69/214 (32%), Positives = 106/214 (49%), Gaps = 3/214 (1%)
Frame = +3
Query: 6 SRRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 185
S R +G PPGP PLPI+GNLL + + L S++YG++ + LG VV
Sbjct: 23 SSRDKGKL-PPGPRPLPILGNLLLLCSQDMLTSLTKL-----SKEYGSMYTVHLGPRRVV 76
Query: 186 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKN 359
V++G + ++E V E F GR D + +F K G+ FS G W R+F ++ L+N
Sbjct: 77 VLSGYQAVKEALVDQGEEFSGRGD--YPAFFNFTKGNGIAFSSGDRWKVLRQFSIQILRN 134
Query: 360 FGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 539
FG R + I EE L+ GEP + ++ NI+ ++ G R+D D+R
Sbjct: 135 FGMGKRSIEERILEEGSFLLAELRKTEGEPFDPTFVLSRSVSNIICSVLFGSRFDYDDER 194
Query: 540 LKKLCSLVMRLFKLXDMS-GGILNFLPFLXHFVP 638
L + L+ F++ G + N P L +VP
Sbjct: 195 LLTIIRLINDNFQIMSSPWGELYNIFPSLLDWVP 228
>BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 98.7 bits (235), Expect = 2e-20
Identities = 66/204 (32%), Positives = 102/204 (50%), Gaps = 4/204 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
PPGP PLP++GNLL + R+ + + +KYG++ + LG VV++ G+E IR
Sbjct: 31 PPGPRPLPLLGNLLQM---DRRGLLKSFL--RFREKYGDVFTVHLGPRPVVMLCGVEAIR 85
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E V E F GR G + F + G++F++G W RRF + +++FG R +
Sbjct: 86 EALVDKAEAFSGR--GKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRSVE 143
Query: 387 VYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCSLVM 566
I EE + L++ G + +FH NI+ +V GKR+ DQ K+ +L
Sbjct: 144 ERIQEEAQCLIEELRKSKGALMDPTFLFHSITANIICSIVFGKRFHYQDQEFLKMLNLFY 203
Query: 567 RLFKLXDMSGGIL--NFLPFLXHF 632
+ F L G L F FL +F
Sbjct: 204 QTFSLISSVFGQLFELFSGFLKYF 227
>AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6
protein.
Length = 491
Score = 97.5 bits (232), Expect = 4e-20
Identities = 65/204 (31%), Positives = 101/204 (49%), Gaps = 4/204 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
PPGP PLP++GNLL + R+ + + +KYG++ + LG VV++ G+E IR
Sbjct: 31 PPGPRPLPLLGNLLQM---DRRGLLKSFL--RFREKYGDVFTVHLGPRPVVMLCGVEAIR 85
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E V E F GR G + F + G++F++G W RRF + +++FG R +
Sbjct: 86 EALVDKAEAFSGR--GKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRSVE 143
Query: 387 VYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCSLVM 566
EE + L++ G + +FH NI+ +V GKR+ DQ K+ +L
Sbjct: 144 ERTQEEAQCLIEELRKSKGALMDATFLFHSITANIICSIVFGKRFHYQDQEFLKMLNLFY 203
Query: 567 RLFKLXDMSGGIL--NFLPFLXHF 632
+ F L G L F FL +F
Sbjct: 204 QTFSLISSVFGQLFELFSGFLKYF 227
>EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1
variant protein.
Length = 491
Score = 96.3 bits (229), Expect = 1e-19
Identities = 68/214 (31%), Positives = 105/214 (49%), Gaps = 3/214 (1%)
Frame = +3
Query: 6 SRRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 185
S R +G PPGP PL I+GNLL + + L S++YG++ + LG VV
Sbjct: 23 SSRDKGKL-PPGPRPLSILGNLLLLCSQDMLTSLTKL-----SKEYGSMYTVHLGPRRVV 76
Query: 186 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKN 359
V++G + ++E V E F GR D + +F K G+ FS G W R+F ++ L+N
Sbjct: 77 VLSGYQAVKEALVDQGEEFSGRGD--YPAFFNFTKGNGIAFSSGDRWKVLRQFSIQILRN 134
Query: 360 FGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 539
FG R + I EE L+ GEP + ++ NI+ ++ G R+D D+R
Sbjct: 135 FGMGKRSIEERILEEGSFLLAELRKTEGEPFDPTFVLSRSVSNIICSVLFGSRFDYDDER 194
Query: 540 LKKLCSLVMRLFKLXDMS-GGILNFLPFLXHFVP 638
L + L+ F++ G + N P L +VP
Sbjct: 195 LLTIIRLINDNFQIMSSPWGELYNIFPSLLDWVP 228
>M29873-1|AAA52143.1| 377|Homo sapiens CYP2B protein.
Length = 377
Score = 95.9 bits (228), Expect = 1e-19
Identities = 64/204 (31%), Positives = 102/204 (50%), Gaps = 4/204 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
PPGP PLP++GNLL + R+ + + +KYG++ + LG VV++ G+E IR
Sbjct: 31 PPGPRPLPLLGNLLQM---DRRGLLKSFL--RFREKYGDVFTVHLGPRPVVMLCGVEAIR 85
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E V N E F GR G M + G++F++G W RRF + +++FG R +
Sbjct: 86 EALVDNAEAFSGR--GKIVIMDPVYQGYGMLFANGNRWKVLRRFSVTTMRDFGMGKRSVE 143
Query: 387 VYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCSLVM 566
I +E + L++ G + +FH NI+ ++ GKR+ DQ K +L
Sbjct: 144 ERIQDEAQCLIEELRKSKGALVDPTFLFHSITANIICSIIFGKRFHYQDQEFLKTLNLFC 203
Query: 567 RLFKL-XDMSGGILN-FLPFLXHF 632
+ F L +S + F FL +F
Sbjct: 204 QSFLLISSISSQLFELFSGFLKYF 227
>BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 95.9 bits (228), Expect = 1e-19
Identities = 65/204 (31%), Positives = 101/204 (49%), Gaps = 4/204 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
PPGP PLP++GNLL + R+ + + +KYG++ + LG VV++ G+E IR
Sbjct: 31 PPGPRPLPLLGNLLQM---DRRGLLKSFL--RFREKYGDVFTVHLGPRPVVMLCGVEAIR 85
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E V E F GR G + F + G++F++G W RRF + +++FG R +
Sbjct: 86 EALVDKAEAFSGR--GKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRSVE 143
Query: 387 VYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCSLVM 566
I EE + L++ G + +F NI+ +V GKR+ DQ K+ +L
Sbjct: 144 ERIQEEAQCLIEELRKSKGALMDPTFLFQSITANIICSIVFGKRFHYQDQEFLKMLNLFY 203
Query: 567 RLFKLXDMSGGIL--NFLPFLXHF 632
+ F L G L F FL +F
Sbjct: 204 QTFSLISSVFGQLFELFSGFLTYF 227
>BC041174-1|AAH41174.1| 377|Homo sapiens CYP2B7P1 protein protein.
Length = 377
Score = 95.9 bits (228), Expect = 1e-19
Identities = 64/204 (31%), Positives = 102/204 (50%), Gaps = 4/204 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
PPGP PLP++GNLL + R+ + + +KYG++ + LG VV++ G+E IR
Sbjct: 31 PPGPRPLPLLGNLLQM---DRRGLLKSFL--RFREKYGDVFTVHLGPRPVVMLCGVEAIR 85
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E V N E F GR G M + G++F++G W RRF + +++FG R +
Sbjct: 86 EALVDNAEAFSGR--GKIVIMDPVYQGYGMLFANGNRWKVLRRFSVTTMRDFGMGKRSVE 143
Query: 387 VYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCSLVM 566
I +E + L++ G + +FH NI+ ++ GKR+ DQ K +L
Sbjct: 144 ERIQDEAQCLIEELRKSKGALVDPTFLFHSITANIICSIIFGKRFHYQDQEFLKTLNLFC 203
Query: 567 RLFKL-XDMSGGILN-FLPFLXHF 632
+ F L +S + F FL +F
Sbjct: 204 QSFLLISSISSQLFELFSGFLKYF 227
>AK223113-1|BAD96833.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 variant protein.
Length = 512
Score = 95.9 bits (228), Expect = 1e-19
Identities = 68/243 (27%), Positives = 122/243 (50%), Gaps = 12/243 (4%)
Frame = +3
Query: 18 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 197
+GL PPGP P++G++L++ K HL SQ+YG++L +R+GS VVV++G
Sbjct: 35 KGLKNPPGPWDWPLIGHMLTL------GKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSG 88
Query: 198 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 368
++ IR+ V + F+GRPD + +T+ S G+ + GP W RR LK+F
Sbjct: 89 LDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIA 148
Query: 369 ------NSRFMNVYIGEECEALVQLRLADAGEPILVNQMFH--ITIVNILWRLVAGKRYD 524
S ++ ++ +E E L+ P N + +++ N++ + G+RYD
Sbjct: 149 SDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYD 208
Query: 525 LXDQRLKKLCSLVMRLFKLXDMSGGILNFLPFLXHFV-PRLIGFTELQXIHNALHQYLRE 701
Q L L +L ++ SG +F+P L + P L F +L + + ++++
Sbjct: 209 HNHQELLSLVNLNNNFGEVVG-SGNPADFIPILRYLPNPSLNAFKDL---NEKFYSFMQK 264
Query: 702 IIK 710
++K
Sbjct: 265 MVK 267
>X04300-1|CAA27843.1| 512|Homo sapiens P-450 c protein.
Length = 512
Score = 95.5 bits (227), Expect = 2e-19
Identities = 68/243 (27%), Positives = 122/243 (50%), Gaps = 12/243 (4%)
Frame = +3
Query: 18 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 197
+GL PPGP P++G++L++ K HL SQ+YG++L +R+GS VVV++G
Sbjct: 35 KGLKNPPGPWGWPLIGHMLTL------GKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSG 88
Query: 198 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 368
++ IR+ V + F+GRPD + +T+ S G+ + GP W RR LK+F
Sbjct: 89 LDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIA 148
Query: 369 ------NSRFMNVYIGEECEALVQLRLADAGEPILVNQMFH--ITIVNILWRLVAGKRYD 524
S ++ ++ +E E L+ P N + +++ N++ + G+RYD
Sbjct: 149 SDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYD 208
Query: 525 LXDQRLKKLCSLVMRLFKLXDMSGGILNFLPFLXHFV-PRLIGFTELQXIHNALHQYLRE 701
Q L L +L ++ SG +F+P L + P L F +L + + ++++
Sbjct: 209 HNHQELLSLVNLNNNFGEVVG-SGNPADFIPILRYLPNPSLNAFKDL---NEKFYSFMQK 264
Query: 702 IIK 710
++K
Sbjct: 265 MVK 267
>X02612-1|CAA26458.1| 512|Homo sapiens cytochrome P(1)-450 protein.
Length = 512
Score = 95.5 bits (227), Expect = 2e-19
Identities = 68/243 (27%), Positives = 122/243 (50%), Gaps = 12/243 (4%)
Frame = +3
Query: 18 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 197
+GL PPGP P++G++L++ K HL SQ+YG++L +R+GS VVV++G
Sbjct: 35 KGLKNPPGPWGWPLIGHMLTL------GKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSG 88
Query: 198 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 368
++ IR+ V + F+GRPD + +T+ S G+ + GP W RR LK+F
Sbjct: 89 LDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIA 148
Query: 369 ------NSRFMNVYIGEECEALVQLRLADAGEPILVNQMFH--ITIVNILWRLVAGKRYD 524
S ++ ++ +E E L+ P N + +++ N++ + G+RYD
Sbjct: 149 SDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYD 208
Query: 525 LXDQRLKKLCSLVMRLFKLXDMSGGILNFLPFLXHFV-PRLIGFTELQXIHNALHQYLRE 701
Q L L +L ++ SG +F+P L + P L F +L + + ++++
Sbjct: 209 HNHQELLSLVNLNNNFGEVVG-SGNPADFIPILRYLPNPSLNAFKDL---NEKFYSFMQK 264
Query: 702 IIK 710
++K
Sbjct: 265 MVK 267
>M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein.
Length = 491
Score = 95.5 bits (227), Expect = 2e-19
Identities = 65/204 (31%), Positives = 101/204 (49%), Gaps = 4/204 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
PPGP PLP++GNLL + R+ + + +KYG++ + LG VV++ G+E IR
Sbjct: 31 PPGPRPLPLLGNLLQM---DRRGLLKSFL--RFREKYGDVFTVHLGPRPVVMLCGVEAIR 85
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E V E F GR G + F + G++F++G W RRF + +++FG R +
Sbjct: 86 EALVDKAEAFSGR--GKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRSVE 143
Query: 387 VYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCSLVM 566
I EE + L++ G + +F NI+ +V GKR+ DQ K+ +L
Sbjct: 144 ERIQEEAQCLIEELRKSKGALMDPTFLFQSITANIICSIVFGKRFHYQDQEFLKMLNLFY 203
Query: 567 RLFKLXDMSGGIL--NFLPFLXHF 632
+ F L G L F FL +F
Sbjct: 204 QTFSLISSVFGQLFELFSGFLKYF 227
>EF094025-1|ABK41999.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 protein.
Length = 512
Score = 95.5 bits (227), Expect = 2e-19
Identities = 68/243 (27%), Positives = 122/243 (50%), Gaps = 12/243 (4%)
Frame = +3
Query: 18 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 197
+GL PPGP P++G++L++ K HL SQ+YG++L +R+GS VVV++G
Sbjct: 35 KGLKNPPGPWGWPLIGHMLTL------GKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSG 88
Query: 198 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 368
++ IR+ V + F+GRPD + +T+ S G+ + GP W RR LK+F
Sbjct: 89 LDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIA 148
Query: 369 ------NSRFMNVYIGEECEALVQLRLADAGEPILVNQMFH--ITIVNILWRLVAGKRYD 524
S ++ ++ +E E L+ P N + +++ N++ + G+RYD
Sbjct: 149 SDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYD 208
Query: 525 LXDQRLKKLCSLVMRLFKLXDMSGGILNFLPFLXHFV-PRLIGFTELQXIHNALHQYLRE 701
Q L L +L ++ SG +F+P L + P L F +L + + ++++
Sbjct: 209 HNHQELLSLVNLNNNFGEVVG-SGNPADFIPILRYLPNPSLNAFKDL---NEKFYSFMQK 264
Query: 702 IIK 710
++K
Sbjct: 265 MVK 267
>DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 95.5 bits (227), Expect = 2e-19
Identities = 65/204 (31%), Positives = 101/204 (49%), Gaps = 4/204 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
PPGP PLP++GNLL + R+ + + +KYG++ + LG VV++ G+E IR
Sbjct: 31 PPGPRPLPLLGNLLQM---DRRGLLKSFL--RFREKYGDVFTVHLGPRPVVMLCGVEAIR 85
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E V E F GR G + F + G++F++G W RRF + +++FG R +
Sbjct: 86 EALVDKAEAFSGR--GKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRSVE 143
Query: 387 VYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCSLVM 566
I EE + L++ G + +F NI+ +V GKR+ DQ K+ +L
Sbjct: 144 ERIQEEAQCLIEELRKSKGALMDPTFLFQSITANIICSIVFGKRFHYQDQEFLKMLNLFY 203
Query: 567 RLFKLXDMSGGIL--NFLPFLXHF 632
+ F L G L F FL +F
Sbjct: 204 QTFSLISSVFGQLFELFSGFLKYF 227
>BC023019-1|AAH23019.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 protein.
Length = 512
Score = 95.5 bits (227), Expect = 2e-19
Identities = 68/243 (27%), Positives = 122/243 (50%), Gaps = 12/243 (4%)
Frame = +3
Query: 18 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 197
+GL PPGP P++G++L++ K HL SQ+YG++L +R+GS VVV++G
Sbjct: 35 KGLKNPPGPWGWPLIGHMLTL------GKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSG 88
Query: 198 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 368
++ IR+ V + F+GRPD + +T+ S G+ + GP W RR LK+F
Sbjct: 89 LDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIA 148
Query: 369 ------NSRFMNVYIGEECEALVQLRLADAGEPILVNQMFH--ITIVNILWRLVAGKRYD 524
S ++ ++ +E E L+ P N + +++ N++ + G+RYD
Sbjct: 149 SDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYD 208
Query: 525 LXDQRLKKLCSLVMRLFKLXDMSGGILNFLPFLXHFV-PRLIGFTELQXIHNALHQYLRE 701
Q L L +L ++ SG +F+P L + P L F +L + + ++++
Sbjct: 209 HNHQELLSLVNLNNNFGEVVG-SGNPADFIPILRYLPNPSLNAFKDL---NEKFYSFMQK 264
Query: 702 IIK 710
++K
Sbjct: 265 MVK 267
>AF253322-1|AAK25727.1| 512|Homo sapiens cytochrome P450 protein.
Length = 512
Score = 95.5 bits (227), Expect = 2e-19
Identities = 68/243 (27%), Positives = 122/243 (50%), Gaps = 12/243 (4%)
Frame = +3
Query: 18 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 197
+GL PPGP P++G++L++ K HL SQ+YG++L +R+GS VVV++G
Sbjct: 35 KGLKNPPGPWGWPLIGHMLTL------GKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSG 88
Query: 198 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 368
++ IR+ V + F+GRPD + +T+ S G+ + GP W RR LK+F
Sbjct: 89 LDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIA 148
Query: 369 ------NSRFMNVYIGEECEALVQLRLADAGEPILVNQMFH--ITIVNILWRLVAGKRYD 524
S ++ ++ +E E L+ P N + +++ N++ + G+RYD
Sbjct: 149 SDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYD 208
Query: 525 LXDQRLKKLCSLVMRLFKLXDMSGGILNFLPFLXHFV-PRLIGFTELQXIHNALHQYLRE 701
Q L L +L ++ SG +F+P L + P L F +L + + ++++
Sbjct: 209 HNHQELLSLVNLNNNFGEVVG-SGNPADFIPILRYLPNPSLNAFKDL---NEKFYSFMQK 264
Query: 702 IIK 710
++K
Sbjct: 265 MVK 267
>AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein.
Length = 491
Score = 95.5 bits (227), Expect = 2e-19
Identities = 65/204 (31%), Positives = 101/204 (49%), Gaps = 4/204 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
PPGP PLP++GNLL + R+ + + +KYG++ + LG VV++ G+E IR
Sbjct: 31 PPGPRPLPLLGNLLQM---DRRGLLKSFL--RFREKYGDVFTVHLGPRPVVMLCGVEAIR 85
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E V E F GR G + F + G++F++G W RRF + +++FG R +
Sbjct: 86 EALVDKAEAFSGR--GKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRSVE 143
Query: 387 VYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCSLVM 566
I EE + L++ G + +F NI+ +V GKR+ DQ K+ +L
Sbjct: 144 ERIQEEAQCLIEELRKSKGALMDPTFLFQSITANIICSIVFGKRFHYQDQEFLKMLNLFY 203
Query: 567 RLFKLXDMSGGIL--NFLPFLXHF 632
+ F L G L F FL +F
Sbjct: 204 QTFSLISSVFGQLFELFSGFLKYF 227
>K03191-1|AAA52139.1| 512|Homo sapiens CYP1A1 protein.
Length = 512
Score = 95.1 bits (226), Expect = 2e-19
Identities = 68/243 (27%), Positives = 121/243 (49%), Gaps = 12/243 (4%)
Frame = +3
Query: 18 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 197
+GL PPGP P++G++L++ K HL SQ+YG++L +R+GS VVV++G
Sbjct: 35 KGLKNPPGPWGWPLIGHMLTL------GKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSG 88
Query: 198 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 368
++ IR+ V + F+GRPD + +T+ S G+ + GP W RR LK+F
Sbjct: 89 LDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIA 148
Query: 369 ------NSRFMNVYIGEECEALVQLRLADAGEPILVNQMFH--ITIVNILWRLVAGKRYD 524
S ++ ++ +E E L+ P N + +++ N++ + G+RYD
Sbjct: 149 SDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYD 208
Query: 525 LXDQRLKKLCSLVMRLFKLXDMSGGILNFLPFLXHFV-PRLIGFTELQXIHNALHQYLRE 701
Q L L +L ++ SG F+P L + P L F +L + + ++++
Sbjct: 209 HNHQELLSLVNLNNNFGEVVG-SGNPAEFIPILRYLPNPSLNAFKDL---NEKFYSFMQK 264
Query: 702 IIK 710
++K
Sbjct: 265 MVK 267
>AY871801-1|AAX62803.1| 483|Homo sapiens cytochrome P450 family 1
subfamily A polypeptide 1 protein.
Length = 483
Score = 95.1 bits (226), Expect = 2e-19
Identities = 68/243 (27%), Positives = 122/243 (50%), Gaps = 12/243 (4%)
Frame = +3
Query: 18 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 197
+GL PPGP P++G++L++ K HL SQ+YG++L +R+GS VVV++G
Sbjct: 35 KGLENPPGPWGWPLIGHMLTL------GKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSG 88
Query: 198 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 368
++ IR+ V + F+GRPD + +T+ S G+ + GP W RR LK+F
Sbjct: 89 LDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIA 148
Query: 369 ------NSRFMNVYIGEECEALVQLRLADAGEPILVNQMFH--ITIVNILWRLVAGKRYD 524
S ++ ++ +E E L+ P N + +++ N++ + G+RYD
Sbjct: 149 SDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYD 208
Query: 525 LXDQRLKKLCSLVMRLFKLXDMSGGILNFLPFLXHFV-PRLIGFTELQXIHNALHQYLRE 701
Q L L +L ++ SG +F+P L + P L F +L + + ++++
Sbjct: 209 HNHQELLSLVNLNNNFGEVVG-SGNPADFIPILRYLPNPSLNAFKDL---NEKFYSFMQK 264
Query: 702 IIK 710
++K
Sbjct: 265 MVK 267
>BC109056-1|AAI09057.1| 320|Homo sapiens CYP2F1 protein protein.
Length = 320
Score = 94.3 bits (224), Expect = 4e-19
Identities = 67/214 (31%), Positives = 105/214 (49%), Gaps = 3/214 (1%)
Frame = +3
Query: 6 SRRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 185
S R +G PPGP PL I+GNLL + + L S++YG++ + LG VV
Sbjct: 23 SSRDKGKL-PPGPRPLSILGNLLLLCSQDMLTSLTKL-----SKEYGSMYTVHLGPRRVV 76
Query: 186 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKN 359
V++G + ++E V E F GR D + +F K G+ FS G W R+F ++ L+N
Sbjct: 77 VLSGYQAVKEALVDQGEEFSGRGD--YPAFFNFTKGNGIAFSSGDRWKVLRQFSIQILRN 134
Query: 360 FGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 539
FG R + I EE L+ GEP + ++ NI+ ++ G R+D D+R
Sbjct: 135 FGMGKRSIEERILEEGSFLLAELRKTEGEPFDPTFVLSRSVSNIICSVLFGSRFDYDDER 194
Query: 540 LKKLCSLVMRLFKLXDMS-GGILNFLPFLXHFVP 638
L + L+ F++ G + + P L +VP
Sbjct: 195 LLTIIRLINDNFQIMSSPWGELYDIFPSLLDWVP 228
>DQ282158-1|ABB77906.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 93.5 bits (222), Expect = 7e-19
Identities = 66/220 (30%), Positives = 104/220 (47%), Gaps = 6/220 (2%)
Frame = +3
Query: 9 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 185
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 186 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVLKYL 353
V+ G+ +RE V++ E RP + FG + VF GP W RRF + L
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPIIQILGFGPRSQGVFLARYGPAWREQRRFSVSTL 139
Query: 354 KNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXD 533
+N G + + ++ EE L +G P N + + N++ L G+R++ D
Sbjct: 140 RNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDD 199
Query: 534 QRLKKLCSLVMR-LFKLXDMSGGILNFLPFLXHFVPRLIG 650
R +L L L + +LN +P L H +P L G
Sbjct: 200 PRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>DQ282157-1|ABB77905.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 93.5 bits (222), Expect = 7e-19
Identities = 66/220 (30%), Positives = 104/220 (47%), Gaps = 6/220 (2%)
Frame = +3
Query: 9 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 185
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 186 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVLKYL 353
V+ G+ +RE V++ E RP + FG + VF GP W RRF + L
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPIIQILGFGPRSQGVFLARYGPAWREQRRFSVSTL 139
Query: 354 KNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXD 533
+N G + + ++ EE L +G P N + + N++ L G+R++ D
Sbjct: 140 RNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDD 199
Query: 534 QRLKKLCSLVMR-LFKLXDMSGGILNFLPFLXHFVPRLIG 650
R +L L L + +LN +P L H +P L G
Sbjct: 200 PRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>DQ282153-1|ABB77901.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 93.5 bits (222), Expect = 7e-19
Identities = 66/220 (30%), Positives = 104/220 (47%), Gaps = 6/220 (2%)
Frame = +3
Query: 9 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 185
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 186 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVLKYL 353
V+ G+ +RE V++ E RP + FG + VF GP W RRF + L
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSISTL 139
Query: 354 KNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXD 533
+N G + + ++ EE L +G P N + + N++ L G+R++ D
Sbjct: 140 RNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDD 199
Query: 534 QRLKKLCSLVMR-LFKLXDMSGGILNFLPFLXHFVPRLIG 650
R +L L L + +LN +P L H +P L G
Sbjct: 200 PRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>X08006-1|CAA30807.1| 497|Homo sapiens cytochrome P450 db1 protein.
Length = 497
Score = 93.1 bits (221), Expect = 9e-19
Identities = 66/220 (30%), Positives = 104/220 (47%), Gaps = 6/220 (2%)
Frame = +3
Query: 9 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 185
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 186 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVLKYL 353
V+ G+ +RE V++ E RP + FG + VF GP W RRF + L
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTL 139
Query: 354 KNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXD 533
+N G + + ++ EE L +G P N + + N++ L G+R++ D
Sbjct: 140 RNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDD 199
Query: 534 QRLKKLCSLVMR-LFKLXDMSGGILNFLPFLXHFVPRLIG 650
R +L L L + +LN +P L H +P L G
Sbjct: 200 PRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>M33388-1|AAA53500.1| 497|Homo sapiens cytochrome P450 IID6
protein.
Length = 497
Score = 93.1 bits (221), Expect = 9e-19
Identities = 66/220 (30%), Positives = 104/220 (47%), Gaps = 6/220 (2%)
Frame = +3
Query: 9 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 185
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 186 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVLKYL 353
V+ G+ +RE V++ E RP + FG + VF GP W RRF + L
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTL 139
Query: 354 KNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXD 533
+N G + + ++ EE L +G P N + + N++ L G+R++ D
Sbjct: 140 RNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDD 199
Query: 534 QRLKKLCSLVMR-LFKLXDMSGGILNFLPFLXHFVPRLIG 650
R +L L L + +LN +P L H +P L G
Sbjct: 200 PRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>M20403-1|AAA52153.1| 497|Homo sapiens CYP2D protein.
Length = 497
Score = 93.1 bits (221), Expect = 9e-19
Identities = 66/220 (30%), Positives = 104/220 (47%), Gaps = 6/220 (2%)
Frame = +3
Query: 9 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 185
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 186 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVLKYL 353
V+ G+ +RE V++ E RP + FG + VF GP W RRF + L
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTL 139
Query: 354 KNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXD 533
+N G + + ++ EE L +G P N + + N++ L G+R++ D
Sbjct: 140 RNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDD 199
Query: 534 QRLKKLCSLVMR-LFKLXDMSGGILNFLPFLXHFVPRLIG 650
R +L L L + +LN +P L H +P L G
Sbjct: 200 PRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>DQ282160-1|ABB77908.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 93.1 bits (221), Expect = 9e-19
Identities = 66/220 (30%), Positives = 104/220 (47%), Gaps = 6/220 (2%)
Frame = +3
Query: 9 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 185
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 186 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVLKYL 353
V+ G+ +RE V++ E RP + FG + VF GP W RRF + L
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTL 139
Query: 354 KNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXD 533
+N G + + ++ EE L +G P N + + N++ L G+R++ D
Sbjct: 140 RNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDD 199
Query: 534 QRLKKLCSLVMR-LFKLXDMSGGILNFLPFLXHFVPRLIG 650
R +L L L + +LN +P L H +P L G
Sbjct: 200 PRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>DQ282159-1|ABB77907.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 93.1 bits (221), Expect = 9e-19
Identities = 66/220 (30%), Positives = 104/220 (47%), Gaps = 6/220 (2%)
Frame = +3
Query: 9 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 185
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 186 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVLKYL 353
V+ G+ +RE V++ E RP + FG + VF GP W RRF + L
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTL 139
Query: 354 KNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXD 533
+N G + + ++ EE L +G P N + + N++ L G+R++ D
Sbjct: 140 RNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDD 199
Query: 534 QRLKKLCSLVMR-LFKLXDMSGGILNFLPFLXHFVPRLIG 650
R +L L L + +LN +P L H +P L G
Sbjct: 200 PRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>DQ282156-1|ABB77904.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 93.1 bits (221), Expect = 9e-19
Identities = 66/220 (30%), Positives = 104/220 (47%), Gaps = 6/220 (2%)
Frame = +3
Query: 9 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 185
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 186 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVLKYL 353
V+ G+ +RE V++ E RP + FG + VF GP W RRF + L
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTL 139
Query: 354 KNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXD 533
+N G + + ++ EE L +G P N + + N++ L G+R++ D
Sbjct: 140 RNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDD 199
Query: 534 QRLKKLCSLVMR-LFKLXDMSGGILNFLPFLXHFVPRLIG 650
R +L L L + +LN +P L H +P L G
Sbjct: 200 PRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>DQ282151-1|ABB77899.1| 496|Homo sapiens cytochrome P450 2D6
protein.
Length = 496
Score = 93.1 bits (221), Expect = 9e-19
Identities = 66/220 (30%), Positives = 104/220 (47%), Gaps = 6/220 (2%)
Frame = +3
Query: 9 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 185
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 186 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVLKYL 353
V+ G+ +RE V++ E RP + FG + VF GP W RRF + L
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTL 139
Query: 354 KNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXD 533
+N G + + ++ EE L +G P N + + N++ L G+R++ D
Sbjct: 140 RNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDD 199
Query: 534 QRLKKLCSLVMR-LFKLXDMSGGILNFLPFLXHFVPRLIG 650
R +L L L + +LN +P L H +P L G
Sbjct: 200 PRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>DQ282147-1|ABB77898.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 93.1 bits (221), Expect = 9e-19
Identities = 66/220 (30%), Positives = 104/220 (47%), Gaps = 6/220 (2%)
Frame = +3
Query: 9 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 185
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 186 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVLKYL 353
V+ G+ +RE V++ E RP + FG + VF GP W RRF + L
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTL 139
Query: 354 KNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXD 533
+N G + + ++ EE L +G P N + + N++ L G+R++ D
Sbjct: 140 RNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDD 199
Query: 534 QRLKKLCSLVMR-LFKLXDMSGGILNFLPFLXHFVPRLIG 650
R +L L L + +LN +P L H +P L G
Sbjct: 200 PRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>DQ282146-1|ABB77897.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 93.1 bits (221), Expect = 9e-19
Identities = 66/220 (30%), Positives = 104/220 (47%), Gaps = 6/220 (2%)
Frame = +3
Query: 9 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 185
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 186 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVLKYL 353
V+ G+ +RE V++ E RP + FG + VF GP W RRF + L
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTL 139
Query: 354 KNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXD 533
+N G + + ++ EE L +G P N + + N++ L G+R++ D
Sbjct: 140 RNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDD 199
Query: 534 QRLKKLCSLVMR-LFKLXDMSGGILNFLPFLXHFVPRLIG 650
R +L L L + +LN +P L H +P L G
Sbjct: 200 PRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>DQ282145-1|ABB77896.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 93.1 bits (221), Expect = 9e-19
Identities = 66/220 (30%), Positives = 104/220 (47%), Gaps = 6/220 (2%)
Frame = +3
Query: 9 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 185
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 186 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVLKYL 353
V+ G+ +RE V++ E RP + FG + VF GP W RRF + L
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTL 139
Query: 354 KNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXD 533
+N G + + ++ EE L +G P N + + N++ L G+R++ D
Sbjct: 140 RNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDD 199
Query: 534 QRLKKLCSLVMR-LFKLXDMSGGILNFLPFLXHFVPRLIG 650
R +L L L + +LN +P L H +P L G
Sbjct: 200 PRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>DQ282144-1|ABB77895.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 93.1 bits (221), Expect = 9e-19
Identities = 66/220 (30%), Positives = 104/220 (47%), Gaps = 6/220 (2%)
Frame = +3
Query: 9 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 185
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 186 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVLKYL 353
V+ G+ +RE V++ E RP + FG + VF GP W RRF + L
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTL 139
Query: 354 KNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXD 533
+N G + + ++ EE L +G P N + + N++ L G+R++ D
Sbjct: 140 RNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDD 199
Query: 534 QRLKKLCSLVMR-LFKLXDMSGGILNFLPFLXHFVPRLIG 650
R +L L L + +LN +P L H +P L G
Sbjct: 200 PRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>BC126858-1|AAI26859.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 93.1 bits (221), Expect = 9e-19
Identities = 66/220 (30%), Positives = 104/220 (47%), Gaps = 6/220 (2%)
Frame = +3
Query: 9 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 185
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 186 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVLKYL 353
V+ G+ +RE V++ E RP + FG + VF GP W RRF + L
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTL 139
Query: 354 KNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXD 533
+N G + + ++ EE L +G P N + + N++ L G+R++ D
Sbjct: 140 RNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDD 199
Query: 534 QRLKKLCSLVMR-LFKLXDMSGGILNFLPFLXHFVPRLIG 650
R +L L L + +LN +P L H +P L G
Sbjct: 200 PRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>BC106758-1|AAI06759.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 93.1 bits (221), Expect = 9e-19
Identities = 66/220 (30%), Positives = 104/220 (47%), Gaps = 6/220 (2%)
Frame = +3
Query: 9 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 185
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 186 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVLKYL 353
V+ G+ +RE V++ E RP + FG + VF GP W RRF + L
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTL 139
Query: 354 KNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXD 533
+N G + + ++ EE L +G P N + + N++ L G+R++ D
Sbjct: 140 RNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDD 199
Query: 534 QRLKKLCSLVMR-LFKLXDMSGGILNFLPFLXHFVPRLIG 650
R +L L L + +LN +P L H +P L G
Sbjct: 200 PRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>BC075024-1|AAH75024.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 93.1 bits (221), Expect = 9e-19
Identities = 66/220 (30%), Positives = 104/220 (47%), Gaps = 6/220 (2%)
Frame = +3
Query: 9 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 185
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 186 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVLKYL 353
V+ G+ +RE V++ E RP + FG + VF GP W RRF + L
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTL 139
Query: 354 KNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXD 533
+N G + + ++ EE L +G P N + + N++ L G+R++ D
Sbjct: 140 RNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDD 199
Query: 534 QRLKKLCSLVMR-LFKLXDMSGGILNFLPFLXHFVPRLIG 650
R +L L L + +LN +P L H +P L G
Sbjct: 200 PRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>BC075023-1|AAH75023.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 93.1 bits (221), Expect = 9e-19
Identities = 66/220 (30%), Positives = 104/220 (47%), Gaps = 6/220 (2%)
Frame = +3
Query: 9 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 185
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 186 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVLKYL 353
V+ G+ +RE V++ E RP + FG + VF GP W RRF + L
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTL 139
Query: 354 KNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXD 533
+N G + + ++ EE L +G P N + + N++ L G+R++ D
Sbjct: 140 RNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDD 199
Query: 534 QRLKKLCSLVMR-LFKLXDMSGGILNFLPFLXHFVPRLIG 650
R +L L L + +LN +P L H +P L G
Sbjct: 200 PRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>BC067432-1|AAH67432.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 93.1 bits (221), Expect = 9e-19
Identities = 66/220 (30%), Positives = 104/220 (47%), Gaps = 6/220 (2%)
Frame = +3
Query: 9 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 185
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 186 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVLKYL 353
V+ G+ +RE V++ E RP + FG + VF GP W RRF + L
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTL 139
Query: 354 KNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXD 533
+N G + + ++ EE L +G P N + + N++ L G+R++ D
Sbjct: 140 RNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDD 199
Query: 534 QRLKKLCSLVMR-LFKLXDMSGGILNFLPFLXHFVPRLIG 650
R +L L L + +LN +P L H +P L G
Sbjct: 200 PRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>AY545216-1|AAS55001.1| 497|Homo sapiens cytochrome P4502D6
protein.
Length = 497
Score = 93.1 bits (221), Expect = 9e-19
Identities = 66/220 (30%), Positives = 104/220 (47%), Gaps = 6/220 (2%)
Frame = +3
Query: 9 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 185
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 186 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVLKYL 353
V+ G+ +RE V++ E RP + FG + VF GP W RRF + L
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTL 139
Query: 354 KNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXD 533
+N G + + ++ EE L +G P N + + N++ L G+R++ D
Sbjct: 140 RNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDD 199
Query: 534 QRLKKLCSLVMR-LFKLXDMSGGILNFLPFLXHFVPRLIG 650
R +L L L + +LN +P L H +P L G
Sbjct: 200 PRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>AK223108-1|BAD96828.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 variant protein.
Length = 512
Score = 93.1 bits (221), Expect = 9e-19
Identities = 67/243 (27%), Positives = 121/243 (49%), Gaps = 12/243 (4%)
Frame = +3
Query: 18 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 197
+GL PPGP P++G++L++ K HL SQ+YG++L +R+GS VVV++G
Sbjct: 35 KGLKNPPGPWDWPLIGHMLTL------GKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSG 88
Query: 198 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 368
++ IR+ V + F+GRPD + +T+ S G+ + GP W RR LK+F
Sbjct: 89 LDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIA 148
Query: 369 ------NSRFMNVYIGEECEALVQLRLADAGEPILVNQMFH--ITIVNILWRLVAGKRYD 524
S ++ ++ + E L+ P N + +++ N++ + G+RYD
Sbjct: 149 SDPASSTSCYLEEHVSKGAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYD 208
Query: 525 LXDQRLKKLCSLVMRLFKLXDMSGGILNFLPFLXHFV-PRLIGFTELQXIHNALHQYLRE 701
Q L L +L ++ SG +F+P L + P L F +L + + ++++
Sbjct: 209 HNHQELLSLVNLNNNFGEVVG-SGNPADFIPILRYLPNPSLNAFKDL---NEKFYSFMQK 264
Query: 702 IIK 710
++K
Sbjct: 265 MVK 267
>DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 92.7 bits (220), Expect = 1e-18
Identities = 63/212 (29%), Positives = 101/212 (47%), Gaps = 5/212 (2%)
Frame = +3
Query: 30 YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELI 209
YPPGP PLP +GNLL V +++ + C + +++G++ L+L VVV+ G+ +
Sbjct: 33 YPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVVVLNGLAAV 87
Query: 210 RE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVLKYLKNFGYNSR 377
RE V++ E RP + FG + VF GP W RRF + L+N G +
Sbjct: 88 REALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKK 147
Query: 378 FMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCS 557
+ ++ EE L +G P N + + N++ L G+R++ D R +L
Sbjct: 148 SLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLD 207
Query: 558 LVMR-LFKLXDMSGGILNFLPFLXHFVPRLIG 650
L L + +LN +P L H +P L G
Sbjct: 208 LAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>DQ282155-1|ABB77903.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 91.5 bits (217), Expect = 3e-18
Identities = 65/220 (29%), Positives = 104/220 (47%), Gaps = 6/220 (2%)
Frame = +3
Query: 9 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 185
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 186 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVLKYL 353
V+ G+ +RE V++ E RP + FG + VF GP W RRF + L
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTL 139
Query: 354 KNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXD 533
+N G + + ++ +E L +G P N + + N++ L G+R++ D
Sbjct: 140 RNLGLGKKSLEQWVTKEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDD 199
Query: 534 QRLKKLCSLVMR-LFKLXDMSGGILNFLPFLXHFVPRLIG 650
R +L L L + +LN +P L H +P L G
Sbjct: 200 PRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1
protein.
Length = 495
Score = 90.6 bits (215), Expect = 5e-18
Identities = 64/202 (31%), Positives = 99/202 (49%), Gaps = 2/202 (0%)
Frame = +3
Query: 6 SRRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 185
S R +G PPGP PL I+GNLL + + L S++YG++ + LG VV
Sbjct: 23 SSRDKGKL-PPGPRPLSILGNLLLLCSQDMLTSLTKL-----SKEYGSMYTVHLGPRRVV 76
Query: 186 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKN 359
V++G + ++E V E F GR D + +F K G+ FS G W R+F ++ L+N
Sbjct: 77 VLSGYQAVKEALVDQGEEFSGRGD--YPAFFNFTKGNGIAFSSGDRWKVLRQFSIQILRN 134
Query: 360 FGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 539
FG R + I EE L+ GEP + ++ NI+ ++ G R+D D+R
Sbjct: 135 FGMGKRSIEERILEEGSFLLAELRKTEGEPFDPTFVLSRSVSNIICSVLFGSRFDYDDER 194
Query: 540 LKKLCSLVMRLFKLXDMSGGIL 605
L + L+ F++ G L
Sbjct: 195 LLTIIRLINDNFQIMSSPWGEL 216
>J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein.
Length = 491
Score = 89.8 bits (213), Expect = 8e-18
Identities = 64/202 (31%), Positives = 99/202 (49%), Gaps = 2/202 (0%)
Frame = +3
Query: 6 SRRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 185
S R +G PPGP PL I+GNLL + + L S++YG++ + LG VV
Sbjct: 23 SSRDKGKL-PPGPRPLSILGNLLLLCSQDMLTSLTKL-----SKEYGSMYTVHLGPRRVV 76
Query: 186 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKN 359
V++G + ++E V E F GR D + +F K G+ FS G W R+F ++ L+N
Sbjct: 77 VLSGYQAVKEALVDQGEEFSGRGD--YPAFFNFTKGNGIAFSSGDRWKVLRQFSIQILRN 134
Query: 360 FGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 539
FG R + I EE L+ GEP + ++ NI+ ++ G R+D D+R
Sbjct: 135 FGMGKRSIEERILEEGSFLLADVRKTEGEPFDPTFVLSRSVSNIICSVLFGSRFDYDDER 194
Query: 540 LKKLCSLVMRLFKLXDMSGGIL 605
L + L+ F++ G L
Sbjct: 195 LLTIIRLINDNFQIMSSPWGEL 216
>DQ282152-1|ABB77900.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 89.8 bits (213), Expect = 8e-18
Identities = 65/220 (29%), Positives = 103/220 (46%), Gaps = 6/220 (2%)
Frame = +3
Query: 9 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 185
RR R Y PGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYSPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 186 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVLKYL 353
V+ G+ +RE V++ E RP + FG + VF GP W RRF + L
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTL 139
Query: 354 KNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXD 533
+N G + + ++ EE L +G P N + + N++ L G+R++ D
Sbjct: 140 RNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDD 199
Query: 534 QRLKKLCSLVMR-LFKLXDMSGGILNFLPFLXHFVPRLIG 650
R +L L L + +LN +P L H +P L G
Sbjct: 200 PRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>DQ211354-2|ABB01372.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 89.8 bits (213), Expect = 8e-18
Identities = 65/220 (29%), Positives = 103/220 (46%), Gaps = 6/220 (2%)
Frame = +3
Query: 9 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 185
RR R Y PGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYSPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 186 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVLKYL 353
V+ G+ +RE V++ E RP + FG + VF GP W RRF + L
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTL 139
Query: 354 KNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXD 533
+N G + + ++ EE L +G P N + + N++ L G+R++ D
Sbjct: 140 RNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDD 199
Query: 534 QRLKKLCSLVMR-LFKLXDMSGGILNFLPFLXHFVPRLIG 650
R +L L L + +LN +P L H +P L G
Sbjct: 200 PRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>DQ211353-2|ABB01371.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 89.8 bits (213), Expect = 8e-18
Identities = 65/220 (29%), Positives = 103/220 (46%), Gaps = 6/220 (2%)
Frame = +3
Query: 9 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 185
RR R Y PGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYSPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 186 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVLKYL 353
V+ G+ +RE V++ E RP + FG + VF GP W RRF + L
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTL 139
Query: 354 KNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXD 533
+N G + + ++ EE L +G P N + + N++ L G+R++ D
Sbjct: 140 RNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDD 199
Query: 534 QRLKKLCSLVMR-LFKLXDMSGGILNFLPFLXHFVPRLIG 650
R +L L L + +LN +P L H +P L G
Sbjct: 200 PRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>DQ211353-1|ABB01370.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 89.8 bits (213), Expect = 8e-18
Identities = 65/220 (29%), Positives = 103/220 (46%), Gaps = 6/220 (2%)
Frame = +3
Query: 9 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 185
RR R Y PGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYSPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 186 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVLKYL 353
V+ G+ +RE V++ E RP + FG + VF GP W RRF + L
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTL 139
Query: 354 KNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXD 533
+N G + + ++ EE L +G P N + + N++ L G+R++ D
Sbjct: 140 RNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDD 199
Query: 534 QRLKKLCSLVMR-LFKLXDMSGGILNFLPFLXHFVPRLIG 650
R +L L L + +LN +P L H +P L G
Sbjct: 200 PRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>AY310359-1|AAQ76692.1| 484|Homo sapiens cytochrome P450 1A1
variant protein.
Length = 484
Score = 89.0 bits (211), Expect = 1e-17
Identities = 58/192 (30%), Positives = 98/192 (51%), Gaps = 11/192 (5%)
Frame = +3
Query: 18 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 197
+GL PPGP P++G++L++ K HL SQ+YG++L +R+GS VVV++G
Sbjct: 35 KGLKNPPGPWGWPLIGHMLTL------GKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSG 88
Query: 198 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 368
++ IR+ V + F+GRPD + +T+ S G+ + GP W RR LK+F
Sbjct: 89 LDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIA 148
Query: 369 ------NSRFMNVYIGEECEALVQLRLADAGEPILVNQMFH--ITIVNILWRLVAGKRYD 524
S ++ ++ +E E L+ P N + +++ N++ + G+RYD
Sbjct: 149 SDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYD 208
Query: 525 LXDQRLKKLCSL 560
Q L L +L
Sbjct: 209 HNHQELLSLVNL 220
>AM236046-1|CAJ84703.1| 229|Homo sapiens cytochrome P450 1A1
protein.
Length = 229
Score = 89.0 bits (211), Expect = 1e-17
Identities = 58/192 (30%), Positives = 98/192 (51%), Gaps = 11/192 (5%)
Frame = +3
Query: 18 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 197
+GL PPGP P++G++L++ K HL SQ+YG++L +R+GS VVV++G
Sbjct: 35 KGLKNPPGPWGWPLIGHMLTL------GKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSG 88
Query: 198 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 368
++ IR+ V + F+GRPD + +T+ S G+ + GP W RR LK+F
Sbjct: 89 LDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIA 148
Query: 369 ------NSRFMNVYIGEECEALVQLRLADAGEPILVNQMFH--ITIVNILWRLVAGKRYD 524
S ++ ++ +E E L+ P N + +++ N++ + G+RYD
Sbjct: 149 SDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYD 208
Query: 525 LXDQRLKKLCSL 560
Q L L +L
Sbjct: 209 HNHQELLSLVNL 220
>X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mRNA
for P-450 IIA4 protein. ).
Length = 494
Score = 87.8 bits (208), Expect = 3e-17
Identities = 61/193 (31%), Positives = 90/193 (46%), Gaps = 2/193 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
PPGPTPLP +GN L + E + S++YG + + LG VVV+ G + +R
Sbjct: 34 PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVVLCGHDAVR 88
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E V E F GR G T K G+VFS+G + RRF + L++FG R +
Sbjct: 89 EALVDQAEEFSGR--GEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGKRGIE 146
Query: 387 VYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCSLVM 566
I EE L+ G I T+ N++ +V G R+D D+ L +++
Sbjct: 147 ERIQEEAGFLIDAHRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEFLSLLRMML 206
Query: 567 RLFKLXDMSGGIL 605
+F+ S G L
Sbjct: 207 GIFQFTSTSTGQL 219
>X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for
cytochrome P-450IIA. ).
Length = 489
Score = 87.8 bits (208), Expect = 3e-17
Identities = 63/201 (31%), Positives = 95/201 (47%), Gaps = 2/201 (0%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 188
R+++G PPGPTPLP +GN L + E + S++YG + + LG VVV
Sbjct: 22 RKNKGKL-PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVV 75
Query: 189 VTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNF 362
+ G + +RE V E F GR G T K G+VFS+G + RRF + L++F
Sbjct: 76 LCGHDAVREALVDQAEEFSGR--GEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDF 133
Query: 363 GYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRL 542
G R + I EE L+ G I T+ N++ +V G R+D D+
Sbjct: 134 GVGKRGIEERIQEEAGFLIDALRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEF 193
Query: 543 KKLCSLVMRLFKLXDMSGGIL 605
L +++ +F+ S G L
Sbjct: 194 LSLLRMMLGIFQFTSTSTGQL 214
>U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 87.8 bits (208), Expect = 3e-17
Identities = 63/201 (31%), Positives = 98/201 (48%), Gaps = 2/201 (0%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 188
R+ RG PPGPTPLP +GN L + + + C ++ +S+ YG + + LG VVV
Sbjct: 27 RKSRGKL-PPGPTPLPFIGNYLQL---NTEHICDSIM--KFSECYGPVFTIHLGPRRVVV 80
Query: 189 VTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNF 362
+ G + +RE V E F GR G T K G+ FS+G + RF + L++F
Sbjct: 81 LCGHDAVREALVDQAEEFSGR--GEQATFEWVFKGYGVAFSNGERAKQLLRFAIATLRDF 138
Query: 363 GYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRL 542
G R + I EE L++ + G I T+ N++ +V G R+D D+
Sbjct: 139 GVGKRGIEERIQEESGFLIEAIRSTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEF 198
Query: 543 KKLCSLVMRLFKLXDMSGGIL 605
L S+++ +F+ S G L
Sbjct: 199 LSLLSMMLGIFQFTSTSTGQL 219
>BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 87.8 bits (208), Expect = 3e-17
Identities = 61/193 (31%), Positives = 90/193 (46%), Gaps = 2/193 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
PPGPTPLP +GN L + E + S++YG + + LG VVV+ G + +R
Sbjct: 34 PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVVLCGHDAVR 88
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E V E F GR G T K G+VFS+G + RRF + L++FG R +
Sbjct: 89 EALVDQAEEFSGR--GEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGKRGIE 146
Query: 387 VYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCSLVM 566
I EE L+ G I T+ N++ +V G R+D D+ L +++
Sbjct: 147 ERIQEEAGFLIDAHRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEFLSLLRMML 206
Query: 567 RLFKLXDMSGGIL 605
+F+ S G L
Sbjct: 207 GIFQFTSTSTGQL 219
>M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 87.4 bits (207), Expect = 4e-17
Identities = 63/201 (31%), Positives = 98/201 (48%), Gaps = 2/201 (0%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 188
R+ RG PPGPTPLP +GN L + + + C ++ +S+ YG + + LG VVV
Sbjct: 27 RKSRGKL-PPGPTPLPFIGNYLQL---NTEHICDSIM--KFSECYGPVFTIHLGPRRVVV 80
Query: 189 VTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNF 362
+ G + +RE V E F GR G T K G+ FS+G + RF + L++F
Sbjct: 81 LCGHDAVREALVDQAEEFSGR--GEQATFDWVFKGYGVAFSNGERAKQLLRFAIATLRDF 138
Query: 363 GYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRL 542
G R + I EE L++ + G I T+ N++ +V G R+D D+
Sbjct: 139 GVGKRGIEERIQEESGFLIEAIRSSHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEF 198
Query: 543 KKLCSLVMRLFKLXDMSGGIL 605
L S+++ +F+ S G L
Sbjct: 199 LSLLSMMLGIFQFTSTSTGQL 219
>DQ282162-1|ABB77909.1| 500|Homo sapiens cytochrome P450 2D6
protein.
Length = 500
Score = 87.4 bits (207), Expect = 4e-17
Identities = 66/223 (29%), Positives = 104/223 (46%), Gaps = 9/223 (4%)
Frame = +3
Query: 9 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 185
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 186 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVLKYL 353
V+ G+ +RE V++ E RP + FG + VF GP W RRF + L
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPIIQILGFGPRSQGVFLARYGPAWREQRRFSVSTL 139
Query: 354 KNFGYNSRFMNVYIGEECEALVQLRLADAG---EPILVNQMFHITIVNILWRLVAGKRYD 524
+N G + + ++ EE L +G P N + + N++ L G+R++
Sbjct: 140 RNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPFRPNGLLDKAVSNVIASLTCGRRFE 199
Query: 525 LXDQRLKKLCSLVMR-LFKLXDMSGGILNFLPFLXHFVPRLIG 650
D R +L L L + +LN +P L H +P L G
Sbjct: 200 YDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 241
>M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 87.0 bits (206), Expect = 6e-17
Identities = 61/193 (31%), Positives = 90/193 (46%), Gaps = 2/193 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
PPGPTPLP +GN L + E + S++YG + + LG VVV+ G + +R
Sbjct: 34 PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVVLCGHDAVR 88
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E V E F GR G T K G+VFS+G + RRF + L++FG R +
Sbjct: 89 EALVDQAEEFSGR--GEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGKRGIE 146
Query: 387 VYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCSLVM 566
I EE L+ G I T+ N++ +V G R+D D+ L +++
Sbjct: 147 ERIQEEAGFLIDALRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEFLSLLRMML 206
Query: 567 RLFKLXDMSGGIL 605
+F+ S G L
Sbjct: 207 GIFQFTSTSTGQL 219
>BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 87.0 bits (206), Expect = 6e-17
Identities = 61/193 (31%), Positives = 90/193 (46%), Gaps = 2/193 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
PPGPTPLP +GN L + E + S++YG + + LG VVV+ G + +R
Sbjct: 34 PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVVLCGHDAVR 88
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E V E F GR G T K G+VFS+G + RRF + L++FG R +
Sbjct: 89 EALVDQAEEFSGR--GEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGKRGIE 146
Query: 387 VYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCSLVM 566
I EE L+ G I T+ N++ +V G R+D D+ L +++
Sbjct: 147 ERIQEEAGFLIDALRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEFLSLLRMML 206
Query: 567 RLFKLXDMSGGIL 605
+F+ S G L
Sbjct: 207 GIFQFTSTSTGQL 219
>BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 87.0 bits (206), Expect = 6e-17
Identities = 61/193 (31%), Positives = 90/193 (46%), Gaps = 2/193 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
PPGPTPLP +GN L + E + S++YG + + LG VVV+ G + +R
Sbjct: 34 PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVVLCGHDAVR 88
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E V E F GR G T K G+VFS+G + RRF + L++FG R +
Sbjct: 89 EALVDQAEEFSGR--GEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGKRGIE 146
Query: 387 VYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCSLVM 566
I EE L+ G I T+ N++ +V G R+D D+ L +++
Sbjct: 147 ERIQEEAGFLIDALRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEFLSLLRMML 206
Query: 567 RLFKLXDMSGGIL 605
+F+ S G L
Sbjct: 207 GIFQFTSTSTGQL 219
>BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 87.0 bits (206), Expect = 6e-17
Identities = 61/193 (31%), Positives = 90/193 (46%), Gaps = 2/193 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
PPGPTPLP +GN L + E + S++YG + + LG VVV+ G + +R
Sbjct: 34 PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVVLCGHDAVR 88
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E V E F GR G T K G+VFS+G + RRF + L++FG R +
Sbjct: 89 EALVDQAEEFSGR--GEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGKRGIE 146
Query: 387 VYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCSLVM 566
I EE L+ G I T+ N++ +V G R+D D+ L +++
Sbjct: 147 ERIQEEAGFLIDALRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEFLSLLRMML 206
Query: 567 RLFKLXDMSGGIL 605
+F+ S G L
Sbjct: 207 GIFQFTSTSTGQL 219
>AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6
protein.
Length = 494
Score = 87.0 bits (206), Expect = 6e-17
Identities = 61/193 (31%), Positives = 90/193 (46%), Gaps = 2/193 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
PPGPTPLP +GN L + E + S++YG + + LG VVV+ G + +R
Sbjct: 34 PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVVLCGHDAVR 88
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E V E F GR G T K G+VFS+G + RRF + L++FG R +
Sbjct: 89 EALVDQAEEFSGR--GEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGKRGIE 146
Query: 387 VYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCSLVM 566
I EE L+ G I T+ N++ +V G R+D D+ L +++
Sbjct: 147 ERIQEEAGFLIDALRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEFLSLLRMML 206
Query: 567 RLFKLXDMSGGIL 605
+F+ S G L
Sbjct: 207 GIFQFTSTSTGQL 219
>S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein.
Length = 477
Score = 86.6 bits (205), Expect = 8e-17
Identities = 60/204 (29%), Positives = 92/204 (45%), Gaps = 4/204 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
PPGPTPLP++GN+L + + +L S+ YG + L G +VV+ G E ++
Sbjct: 17 PPGPTPLPVIGNILQIGIKDISKSLTNL-----SKVYGPVFTLYFGLKPIVVLHGYEAVK 71
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E + E F GR G F + G+VFS+G W RRF L L+NFG R +
Sbjct: 72 EALIDLGEEFSGR--GIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIE 129
Query: 387 VYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCSLVM 566
+ EE LV+ P + N++ ++ KR+D DQ+ L +
Sbjct: 130 DRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLN 189
Query: 567 RLFKLXDMSGGIL--NFLPFLXHF 632
K+ + NF P + +F
Sbjct: 190 ENIKILSSPWIQICNNFSPIIDYF 213
>M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein.
Length = 485
Score = 86.6 bits (205), Expect = 8e-17
Identities = 60/204 (29%), Positives = 92/204 (45%), Gaps = 4/204 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
PPGPTPLP++GN+L + + +L S+ YG + L G +VV+ G E ++
Sbjct: 25 PPGPTPLPVIGNILQIGIKDISKSLTNL-----SKVYGPVFTLYFGLKPIVVLHGYEAVK 79
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E + E F GR G F + G+VFS+G W RRF L L+NFG R +
Sbjct: 80 EALIDLGEEFSGR--GIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIE 137
Query: 387 VYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCSLVM 566
+ EE LV+ P + N++ ++ KR+D DQ+ L +
Sbjct: 138 DRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLN 197
Query: 567 RLFKLXDMSGGIL--NFLPFLXHF 632
K+ + NF P + +F
Sbjct: 198 ENIKILSSPWIQICNNFSPIIDYF 221
>M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein.
Length = 485
Score = 86.6 bits (205), Expect = 8e-17
Identities = 60/204 (29%), Positives = 92/204 (45%), Gaps = 4/204 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
PPGPTPLP++GN+L + + +L S+ YG + L G +VV+ G E ++
Sbjct: 25 PPGPTPLPVIGNILQIGIKDISKSLTNL-----SKVYGPVFTLYFGLKPIVVLHGYEAVK 79
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E + E F GR G F + G+VFS+G W RRF L L+NFG R +
Sbjct: 80 EALIDLGEEFSGR--GIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIE 137
Query: 387 VYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCSLVM 566
+ EE LV+ P + N++ ++ KR+D DQ+ L +
Sbjct: 138 DRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLN 197
Query: 567 RLFKLXDMSGGIL--NFLPFLXHF 632
K+ + NF P + +F
Sbjct: 198 ENIKILSSPWIQICNNFSPIIDYF 221
>L16880-1|AAD13466.1| 273|Homo sapiens cytochrome P-450 2C protein.
Length = 273
Score = 86.6 bits (205), Expect = 8e-17
Identities = 60/204 (29%), Positives = 92/204 (45%), Gaps = 4/204 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
PPGPTPLP++GN+L + + +L S+ YG + L G +VV+ G E ++
Sbjct: 30 PPGPTPLPVIGNILQIGIKDISKSLTNL-----SKVYGPVFTLYFGLKPIVVLHGYEAVK 84
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E + E F GR G F + G+VFS+G W RRF L L+NFG R +
Sbjct: 85 EALIDLGEEFSGR--GIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIE 142
Query: 387 VYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCSLVM 566
+ EE LV+ P + N++ ++ KR+D DQ+ L +
Sbjct: 143 DRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLN 202
Query: 567 RLFKLXDMSGGIL--NFLPFLXHF 632
K+ + NF P + +F
Sbjct: 203 ENIKILSSPWIQICNNFSPIIDYF 226
>D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein.
Length = 487
Score = 86.6 bits (205), Expect = 8e-17
Identities = 60/204 (29%), Positives = 92/204 (45%), Gaps = 4/204 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
PPGPTPLP++GN+L + + +L S+ YG + L G +VV+ G E ++
Sbjct: 27 PPGPTPLPVIGNILQIGIKDISKSLTNL-----SKVYGPVFTLYFGLKPIVVLHGYEAVK 81
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E + E F GR G F + G+VFS+G W RRF L L+NFG R +
Sbjct: 82 EALIDLGEEFSGR--GIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIE 139
Query: 387 VYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCSLVM 566
+ EE LV+ P + N++ ++ KR+D DQ+ L +
Sbjct: 140 DRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLN 199
Query: 567 RLFKLXDMSGGIL--NFLPFLXHF 632
K+ + NF P + +F
Sbjct: 200 ENIKILSSPWIQICNNFSPIIDYF 223
>BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 86.6 bits (205), Expect = 8e-17
Identities = 60/204 (29%), Positives = 92/204 (45%), Gaps = 4/204 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
PPGPTPLP++GN+L + + +L S+ YG + L G +VV+ G E ++
Sbjct: 30 PPGPTPLPVIGNILQIGIKDISKSLTNL-----SKVYGPVFTLYFGLKPIVVLHGYEAVK 84
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E + E F GR G F + G+VFS+G W RRF L L+NFG R +
Sbjct: 85 EALIDLGEEFSGR--GIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIE 142
Query: 387 VYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCSLVM 566
+ EE LV+ P + N++ ++ KR+D DQ+ L +
Sbjct: 143 DRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLN 202
Query: 567 RLFKLXDMSGGIL--NFLPFLXHF 632
K+ + NF P + +F
Sbjct: 203 ENIKILSSPWIQICNNFSPIIDYF 226
>AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 86.6 bits (205), Expect = 8e-17
Identities = 60/204 (29%), Positives = 92/204 (45%), Gaps = 4/204 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
PPGPTPLP++GN+L + + +L S+ YG + L G +VV+ G E ++
Sbjct: 30 PPGPTPLPVIGNILQIGIKDISKSLTNL-----SKVYGPVFTLYFGLKPIVVLHGYEAVK 84
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E + E F GR G F + G+VFS+G W RRF L L+NFG R +
Sbjct: 85 EALIDLGEEFSGR--GIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIE 142
Query: 387 VYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCSLVM 566
+ EE LV+ P + N++ ++ KR+D DQ+ L +
Sbjct: 143 DRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLN 202
Query: 567 RLFKLXDMSGGIL--NFLPFLXHF 632
K+ + NF P + +F
Sbjct: 203 ENIKILSSPWIQICNNFSPIIDYF 226
>AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 86.6 bits (205), Expect = 8e-17
Identities = 60/204 (29%), Positives = 92/204 (45%), Gaps = 4/204 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
PPGPTPLP++GN+L + + +L S+ YG + L G +VV+ G E ++
Sbjct: 30 PPGPTPLPVIGNILQIGIKDISKSLTNL-----SKVYGPVFTLYFGLKPIVVLHGYEAVK 84
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E + E F GR G F + G+VFS+G W RRF L L+NFG R +
Sbjct: 85 EALIDLGEEFSGR--GIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIE 142
Query: 387 VYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCSLVM 566
+ EE LV+ P + N++ ++ KR+D DQ+ L +
Sbjct: 143 DRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLN 202
Query: 567 RLFKLXDMSGGIL--NFLPFLXHF 632
K+ + NF P + +F
Sbjct: 203 ENIKILSSPWIQICNNFSPIIDYF 226
>AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 86.6 bits (205), Expect = 8e-17
Identities = 60/204 (29%), Positives = 92/204 (45%), Gaps = 4/204 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
PPGPTPLP++GN+L + + +L S+ YG + L G +VV+ G E ++
Sbjct: 30 PPGPTPLPVIGNILQIGIKDISKSLTNL-----SKVYGPVFTLYFGLKPIVVLHGYEAVK 84
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E + E F GR G F + G+VFS+G W RRF L L+NFG R +
Sbjct: 85 EALIDLGEEFSGR--GIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIE 142
Query: 387 VYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCSLVM 566
+ EE LV+ P + N++ ++ KR+D DQ+ L +
Sbjct: 143 DRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLN 202
Query: 567 RLFKLXDMSGGIL--NFLPFLXHF 632
K+ + NF P + +F
Sbjct: 203 ENIKILSSPWIQICNNFSPIIDYF 226
>M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein.
Length = 480
Score = 86.2 bits (204), Expect = 1e-16
Identities = 62/205 (30%), Positives = 93/205 (45%), Gaps = 3/205 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
PPGPTPLPI+GN+L + K C + ++S+ YG + + G +VV G E ++
Sbjct: 20 PPGPTPLPIIGNMLQI---DVKDICKS--FTNFSKVYGPVFTVYFGMNPIVVFHGYEAVK 74
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E + N E F GR G + K LG++ S+G W RRF L L+NFG R +
Sbjct: 75 EALIDNGEEFSGR--GNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIE 132
Query: 387 VYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCSLVM 566
+ EE LV+ P + N++ +V KR+D DQ+ L
Sbjct: 133 DRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQKFLTLMKRFN 192
Query: 567 RLFKLXDMSG-GILNFLPFLXHFVP 638
F++ + + N P L P
Sbjct: 193 ENFRILNSPWIQVCNNFPLLIDCFP 217
>AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13
variant 5 protein.
Length = 494
Score = 85.8 bits (203), Expect = 1e-16
Identities = 69/228 (30%), Positives = 103/228 (45%), Gaps = 5/228 (2%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 188
R+ RG PPGPTPLP +GN L + E + S++YG + + LG VVV
Sbjct: 27 RKSRGKL-PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVV 80
Query: 189 VTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNF 362
+ G + ++E V E F GR G T K G+ FS+G + RRF + L+ F
Sbjct: 81 LCGHDAVKEALVDQAEEFSGR--GEQATFDWLFKGYGVAFSNGERAKQLRRFSIATLRGF 138
Query: 363 GYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRL 542
G R + I EE L++ G I T+ N++ +V G R+D D+
Sbjct: 139 GVGKRGIEERIQEEAGFLIEALRGTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEF 198
Query: 543 KKLCSLVMRLFKLXDMSGGIL--NFLPFLXHFV-PRLIGFTELQXIHN 677
L +++ F+ S G L F + H P+ F ELQ + +
Sbjct: 199 LSLLRMMLGSFQFTATSTGQLYEMFSSVMKHLPGPQQQAFKELQGLED 246
>Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein.
Length = 490
Score = 85.4 bits (202), Expect = 2e-16
Identities = 62/205 (30%), Positives = 92/205 (44%), Gaps = 3/205 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
PPGPTPLPI+GN+L + K C + ++S+ YG + + G +VV G E ++
Sbjct: 30 PPGPTPLPIIGNMLQI---DVKDICKS--FTNFSKVYGPVFTVYFGMNPIVVFHGYEAVK 84
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E + N E F GR G + K LG++ S+G W RRF L L+NFG R +
Sbjct: 85 EALIDNGEEFSGR--GNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIE 142
Query: 387 VYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCSLVM 566
+ EE LV+ P + N++ +V KR+D DQ L
Sbjct: 143 DRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFN 202
Query: 567 RLFKLXDMSG-GILNFLPFLXHFVP 638
F++ + + N P L P
Sbjct: 203 ENFRILNSPWIQVCNNFPLLIDCFP 227
>U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 85.4 bits (202), Expect = 2e-16
Identities = 69/228 (30%), Positives = 102/228 (44%), Gaps = 5/228 (2%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 188
R+ RG PPGPTPLP +GN L + E + S++YG + + LG VVV
Sbjct: 27 RKSRGKL-PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVV 80
Query: 189 VTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNF 362
+ G + ++E V E F GR G T K G+ FS+G + RRF + L+ F
Sbjct: 81 LCGHDAVKEALVDQAEEFSGR--GEQATFDWLFKGYGVAFSNGERAKQLRRFSIATLRGF 138
Query: 363 GYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRL 542
G R + I EE L+ G I T+ N++ +V G R+D D+
Sbjct: 139 GVGKRGIEERIQEEAGFLIDALRGTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEF 198
Query: 543 KKLCSLVMRLFKLXDMSGGIL--NFLPFLXHFV-PRLIGFTELQXIHN 677
L +++ F+ S G L F + H P+ F ELQ + +
Sbjct: 199 LSLLRMMLGRFQFTGTSTGQLYEMFSSVMKHLPGPQQQAFKELQGLED 246
>M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein.
Length = 490
Score = 85.4 bits (202), Expect = 2e-16
Identities = 55/175 (31%), Positives = 83/175 (47%), Gaps = 2/175 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
PPGPTPLP++GN+L + + +L S+ YG + L G +VV+ G E+++
Sbjct: 30 PPGPTPLPVIGNILQIDIKDVSKSLTNL-----SKIYGPVFTLYFGLERMVVLHGYEVVK 84
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E + E F GR G F + G+VFS+G W RRF L L+NFG R +
Sbjct: 85 EALIDLGEEFSGR--GHFPLAERANRGFGIVFSNGKRWKEIRRFSLMTLRNFGMGKRSIE 142
Query: 387 VYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKL 551
+ EE LV+ P + N++ ++ KR+D DQ+ L
Sbjct: 143 DRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFQKRFDYKDQQFLNL 197
>M17398-1|AAA35740.1| 393|Homo sapiens protein ( Human cytochrome
P-450 1 mRNA, complete cds, clone Hp1-2. ).
Length = 393
Score = 85.4 bits (202), Expect = 2e-16
Identities = 62/205 (30%), Positives = 92/205 (44%), Gaps = 3/205 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
PPGPTPLPI+GN+L + K C + ++S+ YG + + G +VV G E ++
Sbjct: 30 PPGPTPLPIIGNMLQI---DVKDICKS--FTNFSKVYGPVFTVYFGMNPIVVFHGYEAVK 84
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E + N E F GR G + K LG++ S+G W RRF L L+NFG R +
Sbjct: 85 EALIDNGEEFSGR--GNSPISQRITKGLGIISSNGKRWKEIRRFSLTNLRNFGMGKRSIE 142
Query: 387 VYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCSLVM 566
+ EE LV+ P + N++ +V KR+D DQ L
Sbjct: 143 DRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFN 202
Query: 567 RLFKLXDMSG-GILNFLPFLXHFVP 638
F++ + + N P L P
Sbjct: 203 ENFRILNSPWIQVCNNFPLLIDCFP 227
>M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrome
P-450 1 functional form mRNA, complete cds. ).
Length = 490
Score = 85.4 bits (202), Expect = 2e-16
Identities = 62/205 (30%), Positives = 92/205 (44%), Gaps = 3/205 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
PPGPTPLPI+GN+L + K C + ++S+ YG + + G +VV G E ++
Sbjct: 30 PPGPTPLPIIGNMLQI---DVKDICKS--FTNFSKVYGPVFTVYFGMNPIVVFHGYEAVK 84
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E + N E F GR G + K LG++ S+G W RRF L L+NFG R +
Sbjct: 85 EALIDNGEEFSGR--GNSPISQRITKGLGIISSNGKRWKEIRRFSLTNLRNFGMGKRSIE 142
Query: 387 VYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCSLVM 566
+ EE LV+ P + N++ +V KR+D DQ L
Sbjct: 143 DRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFN 202
Query: 567 RLFKLXDMSG-GILNFLPFLXHFVP 638
F++ + + N P L P
Sbjct: 203 ENFRILNSPWIQVCNNFPLLIDCFP 227
>AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 85.4 bits (202), Expect = 2e-16
Identities = 55/175 (31%), Positives = 83/175 (47%), Gaps = 2/175 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
PPGPTPLP++GN+L + + +L S+ YG + L G +VV+ G E+++
Sbjct: 30 PPGPTPLPVIGNILQIDIKDVSKSLTNL-----SKIYGPVFTLYFGLERMVVLHGYEVVK 84
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E + E F GR G F + G+VFS+G W RRF L L+NFG R +
Sbjct: 85 EALIDLGEEFSGR--GHFPLAERANRGFGIVFSNGKRWKEIRRFSLMTLRNFGMGKRSIE 142
Query: 387 VYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKL 551
+ EE LV+ P + N++ ++ KR+D DQ+ L
Sbjct: 143 DRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFQKRFDYKDQQFLNL 197
>AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 85.4 bits (202), Expect = 2e-16
Identities = 62/205 (30%), Positives = 92/205 (44%), Gaps = 3/205 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
PPGPTPLPI+GN+L + K C + ++S+ YG + + G +VV G E ++
Sbjct: 30 PPGPTPLPIIGNMLQI---DVKDICKS--FTNFSKVYGPVFTVYFGMNPIVVFHGYEAVK 84
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E + N E F GR G + K LG++ S+G W RRF L L+NFG R +
Sbjct: 85 EALIDNGEEFSGR--GNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIE 142
Query: 387 VYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCSLVM 566
+ EE LV+ P + N++ +V KR+D DQ L
Sbjct: 143 DRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFN 202
Query: 567 RLFKLXDMSG-GILNFLPFLXHFVP 638
F++ + + N P L P
Sbjct: 203 ENFRILNSPWIQVCNNFPLLIDCFP 227
>AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 85.4 bits (202), Expect = 2e-16
Identities = 55/175 (31%), Positives = 83/175 (47%), Gaps = 2/175 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
PPGPTPLP++GN+L + + +L S+ YG + L G +VV+ G E+++
Sbjct: 30 PPGPTPLPVIGNILQIDIKDVSKSLTNL-----SKIYGPVFTLYFGLERMVVLHGYEVVK 84
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E + E F GR G F + G+VFS+G W RRF L L+NFG R +
Sbjct: 85 EALIDLGEEFSGR--GHFPLAERANRGFGIVFSNGKRWKEIRRFSLMTLRNFGMGKRSIE 142
Query: 387 VYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKL 551
+ EE LV+ P + N++ ++ KR+D DQ+ L
Sbjct: 143 DRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFQKRFDYKDQQFLNL 197
>AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 85.4 bits (202), Expect = 2e-16
Identities = 62/205 (30%), Positives = 92/205 (44%), Gaps = 3/205 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
PPGPTPLPI+GN+L + K C + ++S+ YG + + G +VV G E ++
Sbjct: 30 PPGPTPLPIIGNMLQI---DVKDICKS--FTNFSKVYGPVFTVYFGMNPIVVFHGYEAVK 84
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E + N E F GR G + K LG++ S+G W RRF L L+NFG R +
Sbjct: 85 EALIDNGEEFSGR--GNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIE 142
Query: 387 VYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCSLVM 566
+ EE LV+ P + N++ +V KR+D DQ L
Sbjct: 143 DRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFN 202
Query: 567 RLFKLXDMSG-GILNFLPFLXHFVP 638
F++ + + N P L P
Sbjct: 203 ENFRILNSPWIQVCNNFPLLIDCFP 227
>AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 85.4 bits (202), Expect = 2e-16
Identities = 55/175 (31%), Positives = 83/175 (47%), Gaps = 2/175 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
PPGPTPLP++GN+L + + +L S+ YG + L G +VV+ G E+++
Sbjct: 30 PPGPTPLPVIGNILQIDIKDVSKSLTNL-----SKIYGPVFTLYFGLERMVVLHGYEVVK 84
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E + E F GR G F + G+VFS+G W RRF L L+NFG R +
Sbjct: 85 EALIDLGEEFSGR--GHFPLAERANRGFGIVFSNGKRWKEIRRFSLMTLRNFGMGKRSIE 142
Query: 387 VYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKL 551
+ EE LV+ P + N++ ++ KR+D DQ+ L
Sbjct: 143 DRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFQKRFDYKDQQFLNL 197
>BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 7 protein.
Length = 494
Score = 85.0 bits (201), Expect = 2e-16
Identities = 62/201 (30%), Positives = 97/201 (48%), Gaps = 2/201 (0%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 188
R+ RG PPGPTPLP +GN L + + + C ++ +S+ YG + + LG VV
Sbjct: 27 RKSRGKL-PPGPTPLPFIGNYLQL---NTEHICDSIM--KFSECYGPVFTIHLGPRRAVV 80
Query: 189 VTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNF 362
+ G + +RE V E F GR G T K G+ FS+G + RF + L++F
Sbjct: 81 LCGHDAVREALVDQAEEFSGR--GEQATFDWVFKGYGVAFSNGERAKQLLRFAIATLRDF 138
Query: 363 GYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRL 542
G R + I EE L++ + G I T+ N++ +V G R+D D+
Sbjct: 139 GVGKRGIEERIQEESGFLIEAIRSTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEF 198
Query: 543 KKLCSLVMRLFKLXDMSGGIL 605
L S+++ +F+ S G L
Sbjct: 199 LSLLSVMLGIFQFTSTSTGQL 219
>BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 85.0 bits (201), Expect = 2e-16
Identities = 62/205 (30%), Positives = 92/205 (44%), Gaps = 3/205 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
PPGPTPLPI+GN+L + K C + ++S+ YG + + G +VV G E ++
Sbjct: 30 PPGPTPLPIIGNMLQI---DVKDICKS--FTNFSKVYGPVFTVYFGMNPIVVFHGYESVK 84
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E + N E F GR G + K LG++ S+G W RRF L L+NFG R +
Sbjct: 85 EALIDNGEEFSGR--GNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIE 142
Query: 387 VYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCSLVM 566
+ EE LV+ P + N++ +V KR+D DQ L
Sbjct: 143 DRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFN 202
Query: 567 RLFKLXDMSG-GILNFLPFLXHFVP 638
F++ + + N P L P
Sbjct: 203 ENFRILNSPWIQVCNNFPLLIDCFP 227
>AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13
variant 6 protein.
Length = 494
Score = 85.0 bits (201), Expect = 2e-16
Identities = 69/228 (30%), Positives = 102/228 (44%), Gaps = 5/228 (2%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 188
R+ RG PPGPTPLP +GN L + E + S++YG + + LG VVV
Sbjct: 27 RKSRGKL-PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVV 80
Query: 189 VTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNF 362
+ G + ++E V E F GR G T K G+ FS+G + RRF + L+ F
Sbjct: 81 LCGHDAVKEALVDQAEEFSGR--GEQATFDWLFKGYGVAFSNGERAKQLRRFSIATLRGF 138
Query: 363 GYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRL 542
G R + I EE L+ G I T+ N++ +V G R+D D+
Sbjct: 139 GVGKRGIEERIQEEAGFLIDALRGTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEF 198
Query: 543 KKLCSLVMRLFKLXDMSGGIL--NFLPFLXHFV-PRLIGFTELQXIHN 677
L +++ F+ S G L F + H P+ F ELQ + +
Sbjct: 199 LSLLRMMLGSFQFTATSTGQLYEMFSSVMKHLPGPQQQAFKELQGLED 246
>AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13
variant 3 protein.
Length = 494
Score = 85.0 bits (201), Expect = 2e-16
Identities = 69/228 (30%), Positives = 102/228 (44%), Gaps = 5/228 (2%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 188
R+ RG PPGPTPLP +GN L + E + S++YG + + LG VVV
Sbjct: 27 RKSRGKL-PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVV 80
Query: 189 VTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNF 362
+ G + ++E V E F GR G T K G+ FS+G + RRF + L+ F
Sbjct: 81 LCGHDAVKEALVDQAEEFSGR--GEQATFDWLFKGYGVAFSNGERAKQLRRFSIATLRGF 138
Query: 363 GYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRL 542
G R + I EE L+ G I T+ N++ +V G R+D D+
Sbjct: 139 GVGKRGIEERIQEEAGFLIDALRGTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEF 198
Query: 543 KKLCSLVMRLFKLXDMSGGIL--NFLPFLXHFV-PRLIGFTELQXIHN 677
L +++ F+ S G L F + H P+ F ELQ + +
Sbjct: 199 LSLLRMMLGSFQFTATSTGQLYEMFSSVMKHLPGPQQQAFKELQGLED 246
>AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13
variant 2 protein.
Length = 494
Score = 85.0 bits (201), Expect = 2e-16
Identities = 69/228 (30%), Positives = 102/228 (44%), Gaps = 5/228 (2%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 188
R+ RG PPGPTPLP +GN L + E + S++YG + + LG VVV
Sbjct: 27 RKSRGKL-PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVV 80
Query: 189 VTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNF 362
+ G + ++E V E F GR G T K G+ FS+G + RRF + L+ F
Sbjct: 81 LCGHDAVKEALVDQAEEFSGR--GEQATFDWLFKGYGVAFSNGERAKQLRRFSIATLRGF 138
Query: 363 GYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRL 542
G R + I EE L+ G I T+ N++ +V G R+D D+
Sbjct: 139 GVGKRGIEERIQEEAGFLIDALRGTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEF 198
Query: 543 KKLCSLVMRLFKLXDMSGGIL--NFLPFLXHFV-PRLIGFTELQXIHN 677
L +++ F+ S G L F + H P+ F ELQ + +
Sbjct: 199 LSLLRMMLGSFQFTATSTGQLYEMFSSVMKHLPGPQQQAFKELQGLED 246
>AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13
variant 1 protein.
Length = 494
Score = 85.0 bits (201), Expect = 2e-16
Identities = 69/228 (30%), Positives = 102/228 (44%), Gaps = 5/228 (2%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 188
R+ RG PPGPTPLP +GN L + E + S++YG + + LG VVV
Sbjct: 27 RKSRGKL-PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVV 80
Query: 189 VTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNF 362
+ G + ++E V E F GR G T K G+ FS+G + RRF + L+ F
Sbjct: 81 LCGHDAVKEALVDQAEEFSGR--GEQATFDWLFKGYGVAFSNGERAKQLRRFSIATLRGF 138
Query: 363 GYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRL 542
G R + I EE L+ G I T+ N++ +V G R+D D+
Sbjct: 139 GVGKRGIEERIQEEAGFLIDALRGTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEF 198
Query: 543 KKLCSLVMRLFKLXDMSGGIL--NFLPFLXHFV-PRLIGFTELQXIHN 677
L +++ F+ S G L F + H P+ F ELQ + +
Sbjct: 199 LSLLRMMLGSFQFTATSTGQLYEMFSSVMKHLPGPQQQAFKELQGLED 246
>AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13
protein.
Length = 494
Score = 85.0 bits (201), Expect = 2e-16
Identities = 69/228 (30%), Positives = 102/228 (44%), Gaps = 5/228 (2%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 188
R+ RG PPGPTPLP +GN L + E + S++YG + + LG VVV
Sbjct: 27 RKSRGKL-PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVV 80
Query: 189 VTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNF 362
+ G + ++E V E F GR G T K G+ FS+G + RRF + L+ F
Sbjct: 81 LCGHDAVKEALVDQAEEFSGR--GEQATFDWLFKGYGVAFSNGERAKQLRRFSIATLRGF 138
Query: 363 GYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRL 542
G R + I EE L+ G I T+ N++ +V G R+D D+
Sbjct: 139 GVGKRGIEERIQEEAGFLIDALRGTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEF 198
Query: 543 KKLCSLVMRLFKLXDMSGGIL--NFLPFLXHFV-PRLIGFTELQXIHN 677
L +++ F+ S G L F + H P+ F ELQ + +
Sbjct: 199 LSLLRMMLGSFQFTATSTGQLYEMFSSVMKHLPGPQQQAFKELQGLED 246
>U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 84.6 bits (200), Expect = 3e-16
Identities = 60/193 (31%), Positives = 91/193 (47%), Gaps = 2/193 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
PPGPTPLP +GN L + E + S++YG + + LG VVV+ G + +R
Sbjct: 34 PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVVLCGHDAVR 88
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E V E F GR G T K G+VFS+G + RF + L++FG R +
Sbjct: 89 EALVDQAEEFSGR--GEQATFDWVFKGYGVVFSNGERAKQLLRFAIATLRDFGVGKRGIE 146
Query: 387 VYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCSLVM 566
I EE L++ + G I T+ N++ +V G R+D D+ L +++
Sbjct: 147 ERIQEESGFLIEAIRSTHGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEFLSLLRMML 206
Query: 567 RLFKLXDMSGGIL 605
+F+ S G L
Sbjct: 207 GIFQFTSTSTGQL 219
>M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein.
Length = 462
Score = 84.6 bits (200), Expect = 3e-16
Identities = 62/205 (30%), Positives = 91/205 (44%), Gaps = 3/205 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
PPGPTPLPI+GN+L + K C + ++S+ YG + + G +VV G E ++
Sbjct: 2 PPGPTPLPIIGNMLQI---DVKDICKS--FTNFSKVYGPVFTVYFGMNPIVVFHGYEAVK 56
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E + N E F GR G + K LG++ S+G W RRF L L+NFG R +
Sbjct: 57 EALIDNGEEFSGR--GNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIE 114
Query: 387 VYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCSLVM 566
+ EE LV P + N++ +V KR+D DQ L
Sbjct: 115 DRVQEEAHCLVDELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFN 174
Query: 567 RLFKLXDMSG-GILNFLPFLXHFVP 638
F++ + + N P L P
Sbjct: 175 ENFRILNSPWIQVCNNFPLLIDCFP 199
>M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein.
Length = 490
Score = 84.2 bits (199), Expect = 4e-16
Identities = 58/176 (32%), Positives = 86/176 (48%), Gaps = 3/176 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
P GPTPLPI+GN+L + K ++S+ YG + + G +VV+ G E ++
Sbjct: 30 PSGPTPLPIIGNILQL-----DVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVK 84
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E + + E F GR G F K LG++FS+G W RRF L L+NFG R +
Sbjct: 85 EALIDHGEEFSGR--GSFPVAEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGMGKRSIE 142
Query: 387 VYIGEECEALV-QLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKL 551
+ EE LV +LR +A P + N++ ++ R+D DQR L
Sbjct: 143 DRVQEEARCLVEELRKTNA-SPCDPTFILGCAPCNVICSVIFHDRFDYKDQRFLNL 197
>L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18
protein.
Length = 490
Score = 84.2 bits (199), Expect = 4e-16
Identities = 58/176 (32%), Positives = 86/176 (48%), Gaps = 3/176 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
P GPTPLPI+GN+L + K ++S+ YG + + G +VV+ G E ++
Sbjct: 30 PSGPTPLPIIGNILQL-----DVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVK 84
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E + + E F GR G F K LG++FS+G W RRF L L+NFG R +
Sbjct: 85 EALIDHGEEFSGR--GSFPVAEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGMGKRSIE 142
Query: 387 VYIGEECEALV-QLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKL 551
+ EE LV +LR +A P + N++ ++ R+D DQR L
Sbjct: 143 DRVQEEARCLVEELRKTNA-SPCDPTFILGCAPCNVICSVIFHDRFDYKDQRFLNL 197
>BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein.
Length = 431
Score = 84.2 bits (199), Expect = 4e-16
Identities = 58/176 (32%), Positives = 86/176 (48%), Gaps = 3/176 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
P GPTPLPI+GN+L + K ++S+ YG + + G +VV+ G E ++
Sbjct: 30 PSGPTPLPIIGNILQL-----DVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVK 84
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E + + E F GR G F K LG++FS+G W RRF L L+NFG R +
Sbjct: 85 EALIDHGEEFSGR--GSFPVAEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGMGKRSIE 142
Query: 387 VYIGEECEALV-QLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKL 551
+ EE LV +LR +A P + N++ ++ R+D DQR L
Sbjct: 143 DRVQEEARCLVEELRKTNA-SPCDPTFILGCAPCNVICSVIFHDRFDYKDQRFLNL 197
>BC096259-1|AAH96259.1| 443|Homo sapiens CYP2C18 protein protein.
Length = 443
Score = 84.2 bits (199), Expect = 4e-16
Identities = 58/176 (32%), Positives = 86/176 (48%), Gaps = 3/176 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
P GPTPLPI+GN+L + K ++S+ YG + + G +VV+ G E ++
Sbjct: 30 PSGPTPLPIIGNILQL-----DVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVK 84
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E + + E F GR G F K LG++FS+G W RRF L L+NFG R +
Sbjct: 85 EALIDHGEEFSGR--GSFPVAEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGMGKRSIE 142
Query: 387 VYIGEECEALV-QLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKL 551
+ EE LV +LR +A P + N++ ++ R+D DQR L
Sbjct: 143 DRVQEEARCLVEELRKTNA-SPCDPTFILGCAPCNVICSVIFHDRFDYKDQRFLNL 197
>BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 84.2 bits (199), Expect = 4e-16
Identities = 58/176 (32%), Positives = 86/176 (48%), Gaps = 3/176 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
P GPTPLPI+GN+L + K ++S+ YG + + G +VV+ G E ++
Sbjct: 30 PSGPTPLPIIGNILQL-----DVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVK 84
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E + + E F GR G F K LG++FS+G W RRF L L+NFG R +
Sbjct: 85 EALIDHGEEFSGR--GSFPVAEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGMGKRSIE 142
Query: 387 VYIGEECEALV-QLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKL 551
+ EE LV +LR +A P + N++ ++ R+D DQR L
Sbjct: 143 DRVQEEARCLVEELRKTNA-SPCDPTFILGCAPCNVICSVIFHDRFDYKDQRFLNL 197
>BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 84.2 bits (199), Expect = 4e-16
Identities = 58/176 (32%), Positives = 86/176 (48%), Gaps = 3/176 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
P GPTPLPI+GN+L + K ++S+ YG + + G +VV+ G E ++
Sbjct: 30 PSGPTPLPIIGNILQL-----DVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVK 84
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E + + E F GR G F K LG++FS+G W RRF L L+NFG R +
Sbjct: 85 EALIDHGEEFSGR--GSFPVAEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGMGKRSIE 142
Query: 387 VYIGEECEALV-QLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKL 551
+ EE LV +LR +A P + N++ ++ R+D DQR L
Sbjct: 143 DRVQEEARCLVEELRKTNA-SPCDPTFILGCAPCNVICSVIFHDRFDYKDQRFLNL 197
>BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 84.2 bits (199), Expect = 4e-16
Identities = 58/176 (32%), Positives = 86/176 (48%), Gaps = 3/176 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
P GPTPLPI+GN+L + K ++S+ YG + + G +VV+ G E ++
Sbjct: 30 PSGPTPLPIIGNILQL-----DVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVK 84
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E + + E F GR G F K LG++FS+G W RRF L L+NFG R +
Sbjct: 85 EALIDHGEEFSGR--GSFPVAEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGMGKRSIE 142
Query: 387 VYIGEECEALV-QLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKL 551
+ EE LV +LR +A P + N++ ++ R+D DQR L
Sbjct: 143 DRVQEEARCLVEELRKTNA-SPCDPTFILGCAPCNVICSVIFHDRFDYKDQRFLNL 197
>AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 84.2 bits (199), Expect = 4e-16
Identities = 58/176 (32%), Positives = 86/176 (48%), Gaps = 3/176 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
P GPTPLPI+GN+L + K ++S+ YG + + G +VV+ G E ++
Sbjct: 30 PSGPTPLPIIGNILQL-----DVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVK 84
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E + + E F GR G F K LG++FS+G W RRF L L+NFG R +
Sbjct: 85 EALIDHGEEFSGR--GSFPVAEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGMGKRSIE 142
Query: 387 VYIGEECEALV-QLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKL 551
+ EE LV +LR +A P + N++ ++ R+D DQR L
Sbjct: 143 DRVQEEARCLVEELRKTNA-SPCDPTFILGCAPCNVICSVIFHDRFDYKDQRFLNL 197
>AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 variant protein.
Length = 490
Score = 83.0 bits (196), Expect = 1e-15
Identities = 58/176 (32%), Positives = 86/176 (48%), Gaps = 3/176 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
P GPTPLPI+GN+L + K ++S+ YG + + G +VV+ G E ++
Sbjct: 30 PSGPTPLPIIGNILQL-----DVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVK 84
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E + + E F GR G F K LG++FS+G W RRF L L+NFG R +
Sbjct: 85 EALIDHGEEFFGR--GSFPVAEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGMGKRSIE 142
Query: 387 VYIGEECEALV-QLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKL 551
+ EE LV +LR +A P + N++ ++ R+D DQR L
Sbjct: 143 DRVQEEARCLVEELRKTNA-SPCDPTFILGCAPCNVICSVIFHDRFDYKDQRFLNL 197
>J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrome
P450IIE1 (ethanol-inducible) gene, complete cds. ).
Length = 493
Score = 81.8 bits (193), Expect = 2e-15
Identities = 58/212 (27%), Positives = 98/212 (46%), Gaps = 4/212 (1%)
Frame = +3
Query: 15 HRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVT 194
H PPGP PLPI+GNL + + K + +Q++G + L +GS +VV+
Sbjct: 27 HSSWNLPPGPFPLPIIGNLFQL-----ELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMH 81
Query: 195 GIELIRE--VSNREVFEGRPD-GFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFG 365
G + ++E + ++ F GR D F+ R G++F++GPTW RRF L L+N+G
Sbjct: 82 GYKAVKEALLDYKDEFSGRGDLPAFHAHRD----RGIIFNNGPTWKDIRRFSLTTLRNYG 137
Query: 366 YNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLK 545
+ I E L++ G+P + N++ ++ K +D D++
Sbjct: 138 MGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFL 197
Query: 546 KLCSLVMRLFKLXDMSG-GILNFLPFLXHFVP 638
+L L F L + N P H++P
Sbjct: 198 RLMYLFNENFHLLSTPWLQLYNNFPSFLHYLP 229
>J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrome
P-450j mRNA, complete cds. ).
Length = 493
Score = 81.8 bits (193), Expect = 2e-15
Identities = 58/212 (27%), Positives = 98/212 (46%), Gaps = 4/212 (1%)
Frame = +3
Query: 15 HRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVT 194
H PPGP PLPI+GNL + + K + +Q++G + L +GS +VV+
Sbjct: 27 HSSWNLPPGPFPLPIIGNLFQL-----ELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMH 81
Query: 195 GIELIRE--VSNREVFEGRPD-GFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFG 365
G + ++E + ++ F GR D F+ R G++F++GPTW RRF L L+N+G
Sbjct: 82 GYKAVKEALLDYKDEFSGRGDLPAFHAHRD----RGIIFNNGPTWKDIRRFSLTTLRNYG 137
Query: 366 YNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLK 545
+ I E L++ G+P + N++ ++ K +D D++
Sbjct: 138 MGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFL 197
Query: 546 KLCSLVMRLFKLXDMSG-GILNFLPFLXHFVP 638
+L L F L + N P H++P
Sbjct: 198 RLMYLFNENFHLLSTPWLQLYNNFPSFLHYLP 229
>DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 81.8 bits (193), Expect = 2e-15
Identities = 58/212 (27%), Positives = 98/212 (46%), Gaps = 4/212 (1%)
Frame = +3
Query: 15 HRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVT 194
H PPGP PLPI+GNL + + K + +Q++G + L +GS +VV+
Sbjct: 27 HSSWNLPPGPFPLPIIGNLFQL-----ELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMH 81
Query: 195 GIELIRE--VSNREVFEGRPD-GFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFG 365
G + ++E + ++ F GR D F+ R G++F++GPTW RRF L L+N+G
Sbjct: 82 GYKAVKEALLDYKDEFSGRGDLPAFHAHRD----RGIIFNNGPTWKDIRRFSLTTLRNYG 137
Query: 366 YNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLK 545
+ I E L++ G+P + N++ ++ K +D D++
Sbjct: 138 MGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFL 197
Query: 546 KLCSLVMRLFKLXDMSG-GILNFLPFLXHFVP 638
+L L F L + N P H++P
Sbjct: 198 RLMYLFNENFHLLSTPWLQLYNNFPSFLHYLP 229
>DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1
protein.
Length = 493
Score = 81.8 bits (193), Expect = 2e-15
Identities = 58/212 (27%), Positives = 98/212 (46%), Gaps = 4/212 (1%)
Frame = +3
Query: 15 HRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVT 194
H PPGP PLPI+GNL + + K + +Q++G + L +GS +VV+
Sbjct: 27 HSSWNLPPGPFPLPIIGNLFQL-----ELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMH 81
Query: 195 GIELIRE--VSNREVFEGRPD-GFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFG 365
G + ++E + ++ F GR D F+ R G++F++GPTW RRF L L+N+G
Sbjct: 82 GYKAVKEALLDYKDEFSGRGDLPAFHAHRD----RGIIFNNGPTWKDIRRFSLTTLRNYG 137
Query: 366 YNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLK 545
+ I E L++ G+P + N++ ++ K +D D++
Sbjct: 138 MGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFL 197
Query: 546 KLCSLVMRLFKLXDMSG-GILNFLPFLXHFVP 638
+L L F L + N P H++P
Sbjct: 198 RLMYLFNENFHLLSTPWLQLYNNFPSFLHYLP 229
>AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 81.8 bits (193), Expect = 2e-15
Identities = 58/212 (27%), Positives = 98/212 (46%), Gaps = 4/212 (1%)
Frame = +3
Query: 15 HRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVT 194
H PPGP PLPI+GNL + + K + +Q++G + L +GS +VV+
Sbjct: 27 HSSWNLPPGPFPLPIIGNLFQL-----ELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMH 81
Query: 195 GIELIRE--VSNREVFEGRPD-GFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFG 365
G + ++E + ++ F GR D F+ R G++F++GPTW RRF L L+N+G
Sbjct: 82 GYKAVKEALLDYKDEFSGRGDLPAFHAHRD----RGIIFNNGPTWKDIRRFSLTTLRNYG 137
Query: 366 YNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLK 545
+ I E L++ G+P + N++ ++ K +D D++
Sbjct: 138 MGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFL 197
Query: 546 KLCSLVMRLFKLXDMSG-GILNFLPFLXHFVP 638
+L L F L + N P H++P
Sbjct: 198 RLMYLFNENFHLLSTPWLQLYNNFPSFLHYLP 229
>AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1
protein.
Length = 493
Score = 81.8 bits (193), Expect = 2e-15
Identities = 58/212 (27%), Positives = 98/212 (46%), Gaps = 4/212 (1%)
Frame = +3
Query: 15 HRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVT 194
H PPGP PLPI+GNL + + K + +Q++G + L +GS +VV+
Sbjct: 27 HSSWNLPPGPFPLPIIGNLFQL-----ELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMH 81
Query: 195 GIELIRE--VSNREVFEGRPD-GFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFG 365
G + ++E + ++ F GR D F+ R G++F++GPTW RRF L L+N+G
Sbjct: 82 GYKAVKEALLDYKDEFSGRGDLPAFHAHRD----RGIIFNNGPTWKDIRRFSLTTLRNYG 137
Query: 366 YNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLK 545
+ I E L++ G+P + N++ ++ K +D D++
Sbjct: 138 MGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFL 197
Query: 546 KLCSLVMRLFKLXDMSG-GILNFLPFLXHFVP 638
+L L F L + N P H++P
Sbjct: 198 RLMYLFNENFHLLSTPWLQLYNNFPSFLHYLP 229
>BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 81.4 bits (192), Expect = 3e-15
Identities = 58/212 (27%), Positives = 98/212 (46%), Gaps = 4/212 (1%)
Frame = +3
Query: 15 HRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVT 194
H PPGP PLPI+GNL + + K + +Q++G + L +GS +VV+
Sbjct: 27 HSSWNLPPGPFPLPIIGNLFQL-----ELKNIPKSFTRLAQRFGPVFTLCVGSQRMVVMH 81
Query: 195 GIELIRE--VSNREVFEGRPD-GFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFG 365
G + ++E + ++ F GR D F+ R G++F++GPTW RRF L L+N+G
Sbjct: 82 GYKAVKEALLDYKDEFSGRGDLPAFHAHRD----RGIIFNNGPTWKDIRRFSLTTLRNYG 137
Query: 366 YNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLK 545
+ I E L++ G+P + N++ ++ K +D D++
Sbjct: 138 MGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFL 197
Query: 546 KLCSLVMRLFKLXDMSG-GILNFLPFLXHFVP 638
+L L F L + N P H++P
Sbjct: 198 RLMYLFNENFHLLSTPWLQLYNNFPSFLHYLP 229
>AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1
protein.
Length = 462
Score = 81.4 bits (192), Expect = 3e-15
Identities = 57/206 (27%), Positives = 97/206 (47%), Gaps = 4/206 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
PPGP PLPI+GNL + + K + +Q++G + L +GS +VV+ G + ++
Sbjct: 2 PPGPFPLPIIGNLFQL-----ELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMHGYKAVK 56
Query: 213 E--VSNREVFEGRPD-GFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFM 383
E + ++ F GR D F+ R G++F++GPTW RRF L L+N+G +
Sbjct: 57 EALLDYKDEFSGRGDLPAFHAHRD----RGIIFNNGPTWKDIRRFSLTTLRNYGMGKQGN 112
Query: 384 NVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCSLV 563
I E L++ G+P + N++ ++ K +D D++ +L L
Sbjct: 113 ESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFLRLMYLF 172
Query: 564 MRLFKLXDMSG-GILNFLPFLXHFVP 638
F L + N P H++P
Sbjct: 173 NENFHLLSTPWLQLYNNFPSFLHYLP 198
>BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 79.8 bits (188), Expect = 9e-15
Identities = 57/212 (26%), Positives = 97/212 (45%), Gaps = 4/212 (1%)
Frame = +3
Query: 15 HRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVT 194
H PPGP PLPI+GNL + + K + +Q++G + L +GS +VV+
Sbjct: 27 HSSWNLPPGPFPLPIIGNLFQL-----ELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMH 81
Query: 195 GIELIRE--VSNREVFEGRPD-GFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFG 365
G + ++E + ++ F GR D F+ R G++F++GP W RRF L L+N+G
Sbjct: 82 GYKAVKEALLDYKDEFSGRGDLPAFHAHRD----RGIIFNNGPAWKDIRRFSLTTLRNYG 137
Query: 366 YNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLK 545
+ I E L++ G+P + N++ ++ K +D D++
Sbjct: 138 MGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFL 197
Query: 546 KLCSLVMRLFKLXDMSG-GILNFLPFLXHFVP 638
+L L F L + N P H++P
Sbjct: 198 RLMYLFNENFHLLSTPWLQLYNNFPSFLHYLP 229
>S63426-1|ABB76283.1| 214|Homo sapiens (S)-mephenytoin hydroxylase
associated cytochrome P450 protein.
Length = 214
Score = 79.0 bits (186), Expect = 2e-14
Identities = 56/172 (32%), Positives = 83/172 (48%), Gaps = 3/172 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
P GPTPLPI+GN+L + K ++S+ YG + + G +VV+ G E ++
Sbjct: 30 PSGPTPLPIIGNILQL-----DVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVK 84
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E + + E F GR G F K LG++FS+G W RF L L+NFG R +
Sbjct: 85 EALIDHGEEFSGR--GSFPVAEKVNKGLGILFSNGKRWKEIWRFCLMTLRNFGMGKRSIE 142
Query: 387 VYIGEECEALV-QLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 539
+ EE LV +LR +A P + N+ ++ R+D DQR
Sbjct: 143 DRVQEEARCLVEELRKTNA-SPCDPTFILGCAPCNVTCSVIFHDRFDYKDQR 193
>AM233520-1|CAJ80723.1| 189|Homo sapiens cytochrome P450 1A1
protein.
Length = 189
Score = 78.6 bits (185), Expect = 2e-14
Identities = 47/143 (32%), Positives = 78/143 (54%), Gaps = 9/143 (6%)
Frame = +3
Query: 18 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 197
+GL PPGP P++G++L++ K HL SQ+YG++L +R+GS VVV++G
Sbjct: 35 KGLKNPPGPWGWPLIGHMLTL------GKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSG 88
Query: 198 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 368
++ IR+ V + F+GRPD + +T+ S G+ + GP W RR LK+F
Sbjct: 89 LDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIA 148
Query: 369 ------NSRFMNVYIGEECEALV 419
S ++ ++ +E E L+
Sbjct: 149 SDPASSTSCYLEEHVSKEAEVLI 171
>AM233519-1|CAJ80722.1| 189|Homo sapiens cytochrome P450 1A1
protein.
Length = 189
Score = 78.6 bits (185), Expect = 2e-14
Identities = 47/143 (32%), Positives = 78/143 (54%), Gaps = 9/143 (6%)
Frame = +3
Query: 18 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 197
+GL PPGP P++G++L++ K HL SQ+YG++L +R+GS VVV++G
Sbjct: 35 KGLKNPPGPWGWPLIGHMLTL------GKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSG 88
Query: 198 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 368
++ IR+ V + F+GRPD + +T+ S G+ + GP W RR LK+F
Sbjct: 89 LDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIA 148
Query: 369 ------NSRFMNVYIGEECEALV 419
S ++ ++ +E E L+
Sbjct: 149 SDPASSTSCYLEEHVSKEAEVLI 171
>BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family 2,
subfamily U, polypeptide 1 protein.
Length = 544
Score = 78.2 bits (184), Expect = 3e-14
Identities = 73/257 (28%), Positives = 120/257 (46%), Gaps = 23/257 (8%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVL---------WESRKFKCH---------HLIWQSWS 134
RR R PPGPTP P+VGN VL W S + + ++ +
Sbjct: 52 RRRRARGIPPGPTPWPLVGNFGHVLLPPFLRRRSWLSSRTRAAGIDPSVIGPQVLLAHLA 111
Query: 135 QKYGNLLGLRLGSINVVVVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD 308
+ YG++ +G VVV++ +RE V EVF RP ++ + K+ G+VF+
Sbjct: 112 RVYGSIFSFFIGHYLVVVLSDFHSVREALVQQAEVFSDRPRVPLISIVT--KEKGVVFAH 169
Query: 309 -GPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRLADAGE-PILVNQMFHITI 482
GP W + R+F L++FG + I EE + V+ + GE P + +
Sbjct: 170 YGPVWRQQRKFSHSTLRHFGLGKLSLEPKIIEEFK-YVKAEMQKHGEDPFCPFSIISNAV 228
Query: 483 VNILWRLVAGKRYDLXDQRLKKLCSLVMRLFKLXDMSGGIL-NFLPFLXHFVPRLIGFTE 659
NI+ L G+R+D + KK+ + R ++ S +L N P+L +++P F E
Sbjct: 229 SNIICSLCFGQRFDYTNSEFKKMLGFMSRGLEICLNSQVLLVNICPWL-YYLP-FGPFKE 286
Query: 660 LQXIHNALHQYLREIIK 710
L+ I + +L++IIK
Sbjct: 287 LRQIEKDITSFLKKIIK 303
>AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein.
Length = 544
Score = 78.2 bits (184), Expect = 3e-14
Identities = 73/257 (28%), Positives = 120/257 (46%), Gaps = 23/257 (8%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVL---------WESRKFKCH---------HLIWQSWS 134
RR R PPGPTP P+VGN VL W S + + ++ +
Sbjct: 52 RRRRARGIPPGPTPWPLVGNFGHVLLPPFLRRRSWLSSRTRAAGIDPSVIGPQVLLAHLA 111
Query: 135 QKYGNLLGLRLGSINVVVVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD 308
+ YG++ +G VVV++ +RE V EVF RP ++ + K+ G+VF+
Sbjct: 112 RVYGSIFSFFIGHYLVVVLSDFHSVREALVQQAEVFSDRPRVPLISIVT--KEKGVVFAH 169
Query: 309 -GPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRLADAGE-PILVNQMFHITI 482
GP W + R+F L++FG + I EE + V+ + GE P + +
Sbjct: 170 YGPVWRQQRKFSHSTLRHFGLGKLSLEPKIIEEFK-YVKAEMQKHGEDPFCPFSIISNAV 228
Query: 483 VNILWRLVAGKRYDLXDQRLKKLCSLVMRLFKLXDMSGGIL-NFLPFLXHFVPRLIGFTE 659
NI+ L G+R+D + KK+ + R ++ S +L N P+L +++P F E
Sbjct: 229 SNIICSLCFGQRFDYTNSEFKKMLGFMSRGLEICLNSQVLLVNICPWL-YYLP-FGPFKE 286
Query: 660 LQXIHNALHQYLREIIK 710
L+ I + +L++IIK
Sbjct: 287 LRQIEKDITSFLKKIIK 303
>BC070317-1|AAH70317.1| 162|Homo sapiens CYP2C9 protein protein.
Length = 162
Score = 77.4 bits (182), Expect = 5e-14
Identities = 50/140 (35%), Positives = 70/140 (50%), Gaps = 3/140 (2%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
PPGPTPLP++GN+L + + +L S+ YG + L G +VV+ G E ++
Sbjct: 30 PPGPTPLPVIGNILQIGIKDISKSLTNL-----SKVYGPVFTLYFGLKPIVVLHGYEAVK 84
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E + E F GR G F + G+VFS+G W RRF L L+NFG R +
Sbjct: 85 EALIDLGEEFSGR--GIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIE 142
Query: 387 VYIGEECEALV-QLRLADAG 443
+ EE LV +LR G
Sbjct: 143 DCVQEEARCLVEELRKTKGG 162
>BC020754-1|AAH20754.1| 162|Homo sapiens CYP2C9 protein protein.
Length = 162
Score = 77.4 bits (182), Expect = 5e-14
Identities = 50/140 (35%), Positives = 70/140 (50%), Gaps = 3/140 (2%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
PPGPTPLP++GN+L + + +L S+ YG + L G +VV+ G E ++
Sbjct: 30 PPGPTPLPVIGNILQIGIKDISKSLTNL-----SKVYGPVFTLYFGLKPIVVLHGYEAVK 84
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E + E F GR G F + G+VFS+G W RRF L L+NFG R +
Sbjct: 85 EALIDLGEEFSGR--GIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIE 142
Query: 387 VYIGEECEALV-QLRLADAG 443
+ EE LV +LR G
Sbjct: 143 DRVQEEARCLVEELRKTKGG 162
>L39098-1|AAL31347.1| 160|Homo sapiens S-mephenytoin 4-hydroxylase
protein.
Length = 160
Score = 77.0 bits (181), Expect = 6e-14
Identities = 47/132 (35%), Positives = 68/132 (51%), Gaps = 2/132 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 212
PPGPTPLP++GN+L + + +L S+ YG + L G +VV+ G E+++
Sbjct: 30 PPGPTPLPVIGNILQIDIKDVSKSLTNL-----SKIYGPVFTLYFGLERMVVLHGYEVVK 84
Query: 213 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 386
E + E F GR G F + G+VFS+G W RRF L L+NFG R +
Sbjct: 85 EALIDLGEEFSGR--GHFPLAERANRGFGIVFSNGKRWKEIRRFSLMTLRNFGMGKRSIE 142
Query: 387 VYIGEECEALVQ 422
+ EE LV+
Sbjct: 143 DRVQEEARCLVE 154
>BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 76.2 bits (179), Expect = 1e-13
Identities = 56/209 (26%), Positives = 91/209 (43%), Gaps = 4/209 (1%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 188
++ R + +PPGP LP +GN+ S+ S + H+ + SQ YG + L LG I+ VV
Sbjct: 32 KQRRPMGFPPGPPGLPFIGNIYSLAASS---ELPHVYMRKQSQVYGEIFSLDLGGISTVV 88
Query: 189 VTGIELIRE--VSNREVFEGRPD-GFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKN 359
+ G ++++E V E+F RP F M G L + G W RR + +
Sbjct: 89 LNGYDVVKECLVHQSEIFADRPCLPLFMKMTKMGGLLNSRYGRG--WVDHRRLAVNSFRY 146
Query: 360 FGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 539
FGY + I EE + G P Q+ + NI ++ G+R+ D
Sbjct: 147 FGYGQKSFESKILEETKFFNDAIETYKGRPFDFKQLITNAVSNITNLIIFGERFTYEDTD 206
Query: 540 LKKLCSLVMRLFKLXDMSGGIL-NFLPFL 623
+ + L +L + L N P++
Sbjct: 207 FQHMIELFSENVELAASASVFLYNAFPWI 235
>BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 76.2 bits (179), Expect = 1e-13
Identities = 56/209 (26%), Positives = 91/209 (43%), Gaps = 4/209 (1%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 188
++ R + +PPGP LP +GN+ S+ S + H+ + SQ YG + L LG I+ VV
Sbjct: 32 KQRRPMGFPPGPPGLPFIGNIYSLAASS---ELPHVYMRKQSQVYGEIFSLDLGGISTVV 88
Query: 189 VTGIELIRE--VSNREVFEGRPD-GFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKN 359
+ G ++++E V E+F RP F M G L + G W RR + +
Sbjct: 89 LNGYDVVKECLVHQSEIFADRPCLPLFMKMTKMGGLLNSRYGRG--WVDHRRLAVNSFRY 146
Query: 360 FGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 539
FGY + I EE + G P Q+ + NI ++ G+R+ D
Sbjct: 147 FGYGQKSFESKILEETKFFNDAIETYKGRPFDFKQLITNAVSNITNLIIFGERFTYEDTD 206
Query: 540 LKKLCSLVMRLFKLXDMSGGIL-NFLPFL 623
+ + L +L + L N P++
Sbjct: 207 FQHMIELFSENVELAASASVFLYNAFPWI 235
>AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1
protein.
Length = 501
Score = 76.2 bits (179), Expect = 1e-13
Identities = 56/209 (26%), Positives = 91/209 (43%), Gaps = 4/209 (1%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 188
++ R + +PPGP LP +GN+ S+ S + H+ + SQ YG + L LG I+ VV
Sbjct: 32 KQRRPMGFPPGPPGLPFIGNIYSLAASS---ELPHVYMRKQSQVYGEIFSLDLGGISTVV 88
Query: 189 VTGIELIRE--VSNREVFEGRPD-GFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKN 359
+ G ++++E V E+F RP F M G L + G W RR + +
Sbjct: 89 LNGYDVVKECLVHQSEIFADRPCLPLFMKMTKMGGLLNSRYGRG--WVDHRRLAVNSFRY 146
Query: 360 FGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 539
FGY + I EE + G P Q+ + NI ++ G+R+ D
Sbjct: 147 FGYGQKSFESKILEETKFFNDAIETYKGRPFDFKQLITNAVSNITNLIIFGERFTYEDTD 206
Query: 540 LKKLCSLVMRLFKLXDMSGGIL-NFLPFL 623
+ + L +L + L N P++
Sbjct: 207 FQHMIELFSENVELAASASVFLYNAFPWI 235
>Z00036-1|CAA77335.1| 515|Homo sapiens protein ( Human mRNA for
cytochrome P-3-450. ).
Length = 515
Score = 74.1 bits (174), Expect = 4e-13
Identities = 57/216 (26%), Positives = 103/216 (47%), Gaps = 12/216 (5%)
Frame = +3
Query: 18 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 197
+GL PP P P++G++L++ K HL SQ+YG++L +R+GS V+V++
Sbjct: 37 KGLKSPPEPWGWPLLGHVLTL------GKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSR 90
Query: 198 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 368
++ IR+ V + F+GRPD + T+ + G+ L GP W RR L F
Sbjct: 91 LDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRLAQNALNTFSIA 150
Query: 369 ------NSRFMNVYIGEECEALV---QLRLADAGEPILVNQMFHITIVNILWRLVAGKRY 521
+S ++ ++ +E +AL+ Q +A G NQ+ +++ N++ + G+ +
Sbjct: 151 SDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVV-VSVANVIGAMCFGQHF 209
Query: 522 DLXDQRLKKLCSLVMRLFKLXDMSGGILNFLPFLXH 629
+ L + SG L+F P L +
Sbjct: 210 PESSDEMLSLVKNTHEFVETAS-SGNPLDFFPILRY 244
>M55053-1|AAA52146.1| 515|Homo sapiens cytochrome P3-450 protein.
Length = 515
Score = 74.1 bits (174), Expect = 4e-13
Identities = 57/216 (26%), Positives = 103/216 (47%), Gaps = 12/216 (5%)
Frame = +3
Query: 18 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 197
+GL PP P P++G++L++ K HL SQ+YG++L +R+GS V+V++
Sbjct: 37 KGLKSPPEPWGWPLLGHVLTL------GKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSR 90
Query: 198 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 368
++ IR+ V + F+GRPD + T+ + G+ L GP W RR L F
Sbjct: 91 LDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRLAQNALNTFSIA 150
Query: 369 ------NSRFMNVYIGEECEALV---QLRLADAGEPILVNQMFHITIVNILWRLVAGKRY 521
+S ++ ++ +E +AL+ Q +A G NQ+ +++ N++ + G+ +
Sbjct: 151 SDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVV-VSVANVIGAMCFGQHF 209
Query: 522 DLXDQRLKKLCSLVMRLFKLXDMSGGILNFLPFLXH 629
+ L + SG L+F P L +
Sbjct: 210 PESSDEMLSLVKNTHEFVETAS-SGNPLDFFPILRY 244
>M31667-1|AAA52163.1| 515|Homo sapiens CYP1A2 protein.
Length = 515
Score = 74.1 bits (174), Expect = 4e-13
Identities = 57/216 (26%), Positives = 103/216 (47%), Gaps = 12/216 (5%)
Frame = +3
Query: 18 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 197
+GL PP P P++G++L++ K HL SQ+YG++L +R+GS V+V++
Sbjct: 37 KGLKSPPEPWGWPLLGHVLTL------GKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSR 90
Query: 198 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 368
++ IR+ V + F+GRPD + T+ + G+ L GP W RR L F
Sbjct: 91 LDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRLAQNALNTFSIA 150
Query: 369 ------NSRFMNVYIGEECEALV---QLRLADAGEPILVNQMFHITIVNILWRLVAGKRY 521
+S ++ ++ +E +AL+ Q +A G NQ+ +++ N++ + G+ +
Sbjct: 151 SDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVV-VSVANVIGAMCFGQHF 209
Query: 522 DLXDQRLKKLCSLVMRLFKLXDMSGGILNFLPFLXH 629
+ L + SG L+F P L +
Sbjct: 210 PESSDEMLSLVKNTHEFVETAS-SGNPLDFFPILRY 244
>DQ022432-1|AAY26399.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 74.1 bits (174), Expect = 4e-13
Identities = 57/216 (26%), Positives = 103/216 (47%), Gaps = 12/216 (5%)
Frame = +3
Query: 18 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 197
+GL PP P P++G++L++ K HL SQ+YG++L +R+GS V+V++
Sbjct: 37 KGLKSPPEPWGWPLLGHVLTL------GKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSR 90
Query: 198 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 368
++ IR+ V + F+GRPD + T+ + G+ L GP W RR L F
Sbjct: 91 LDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRLAQNALNTFSIA 150
Query: 369 ------NSRFMNVYIGEECEALV---QLRLADAGEPILVNQMFHITIVNILWRLVAGKRY 521
+S ++ ++ +E +AL+ Q +A G NQ+ +++ N++ + G+ +
Sbjct: 151 SDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVV-VSVANVIGAMCFGQHF 209
Query: 522 DLXDQRLKKLCSLVMRLFKLXDMSGGILNFLPFLXH 629
+ L + SG L+F P L +
Sbjct: 210 PESSDEMLSLVKNTHEFVETAS-SGNPLDFFPILRY 244
>BC067429-1|AAH67429.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 74.1 bits (174), Expect = 4e-13
Identities = 57/216 (26%), Positives = 103/216 (47%), Gaps = 12/216 (5%)
Frame = +3
Query: 18 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 197
+GL PP P P++G++L++ K HL SQ+YG++L +R+GS V+V++
Sbjct: 37 KGLKSPPEPWGWPLLGHVLTL------GKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSR 90
Query: 198 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 368
++ IR+ V + F+GRPD + T+ + G+ L GP W RR L F
Sbjct: 91 LDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRLAQNALNTFSIA 150
Query: 369 ------NSRFMNVYIGEECEALV---QLRLADAGEPILVNQMFHITIVNILWRLVAGKRY 521
+S ++ ++ +E +AL+ Q +A G NQ+ +++ N++ + G+ +
Sbjct: 151 SDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVV-VSVANVIGAMCFGQHF 209
Query: 522 DLXDQRLKKLCSLVMRLFKLXDMSGGILNFLPFLXH 629
+ L + SG L+F P L +
Sbjct: 210 PESSDEMLSLVKNTHEFVETAS-SGNPLDFFPILRY 244
>BC067428-1|AAH67428.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 74.1 bits (174), Expect = 4e-13
Identities = 57/216 (26%), Positives = 103/216 (47%), Gaps = 12/216 (5%)
Frame = +3
Query: 18 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 197
+GL PP P P++G++L++ K HL SQ+YG++L +R+GS V+V++
Sbjct: 37 KGLKSPPEPWGWPLLGHVLTL------GKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSR 90
Query: 198 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 368
++ IR+ V + F+GRPD + T+ + G+ L GP W RR L F
Sbjct: 91 LDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRLAQNALNTFSIA 150
Query: 369 ------NSRFMNVYIGEECEALV---QLRLADAGEPILVNQMFHITIVNILWRLVAGKRY 521
+S ++ ++ +E +AL+ Q +A G NQ+ +++ N++ + G+ +
Sbjct: 151 SDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVV-VSVANVIGAMCFGQHF 209
Query: 522 DLXDQRLKKLCSLVMRLFKLXDMSGGILNFLPFLXH 629
+ L + SG L+F P L +
Sbjct: 210 PESSDEMLSLVKNTHEFVETAS-SGNPLDFFPILRY 244
>BC067426-1|AAH67426.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 74.1 bits (174), Expect = 4e-13
Identities = 57/216 (26%), Positives = 103/216 (47%), Gaps = 12/216 (5%)
Frame = +3
Query: 18 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 197
+GL PP P P++G++L++ K HL SQ+YG++L +R+GS V+V++
Sbjct: 37 KGLKSPPEPWGWPLLGHVLTL------GKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSR 90
Query: 198 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 368
++ IR+ V + F+GRPD + T+ + G+ L GP W RR L F
Sbjct: 91 LDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRLAQNALNTFSIA 150
Query: 369 ------NSRFMNVYIGEECEALV---QLRLADAGEPILVNQMFHITIVNILWRLVAGKRY 521
+S ++ ++ +E +AL+ Q +A G NQ+ +++ N++ + G+ +
Sbjct: 151 SDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVV-VSVANVIGAMCFGQHF 209
Query: 522 DLXDQRLKKLCSLVMRLFKLXDMSGGILNFLPFLXH 629
+ L + SG L+F P L +
Sbjct: 210 PESSDEMLSLVKNTHEFVETAS-SGNPLDFFPILRY 244
>BC067425-1|AAH67425.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 74.1 bits (174), Expect = 4e-13
Identities = 57/216 (26%), Positives = 103/216 (47%), Gaps = 12/216 (5%)
Frame = +3
Query: 18 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 197
+GL PP P P++G++L++ K HL SQ+YG++L +R+GS V+V++
Sbjct: 37 KGLKSPPEPWGWPLLGHVLTL------GKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSR 90
Query: 198 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 368
++ IR+ V + F+GRPD + T+ + G+ L GP W RR L F
Sbjct: 91 LDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRLAQNALNTFSIA 150
Query: 369 ------NSRFMNVYIGEECEALV---QLRLADAGEPILVNQMFHITIVNILWRLVAGKRY 521
+S ++ ++ +E +AL+ Q +A G NQ+ +++ N++ + G+ +
Sbjct: 151 SDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVV-VSVANVIGAMCFGQHF 209
Query: 522 DLXDQRLKKLCSLVMRLFKLXDMSGGILNFLPFLXH 629
+ L + SG L+F P L +
Sbjct: 210 PESSDEMLSLVKNTHEFVETAS-SGNPLDFFPILRY 244
>BC067424-1|AAH67424.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 74.1 bits (174), Expect = 4e-13
Identities = 57/216 (26%), Positives = 103/216 (47%), Gaps = 12/216 (5%)
Frame = +3
Query: 18 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 197
+GL PP P P++G++L++ K HL SQ+YG++L +R+GS V+V++
Sbjct: 37 KGLKSPPEPWGWPLLGHVLTL------GKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSR 90
Query: 198 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 368
++ IR+ V + F+GRPD + T+ + G+ L GP W RR L F
Sbjct: 91 LDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRLAQNALNTFSIA 150
Query: 369 ------NSRFMNVYIGEECEALV---QLRLADAGEPILVNQMFHITIVNILWRLVAGKRY 521
+S ++ ++ +E +AL+ Q +A G NQ+ +++ N++ + G+ +
Sbjct: 151 SDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVV-VSVANVIGAMCFGQHF 209
Query: 522 DLXDQRLKKLCSLVMRLFKLXDMSGGILNFLPFLXH 629
+ L + SG L+F P L +
Sbjct: 210 PESSDEMLSLVKNTHEFVETAS-SGNPLDFFPILRY 244
>AF253322-2|AAK25728.1| 516|Homo sapiens cytochrome P450 protein.
Length = 516
Score = 74.1 bits (174), Expect = 4e-13
Identities = 57/216 (26%), Positives = 103/216 (47%), Gaps = 12/216 (5%)
Frame = +3
Query: 18 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 197
+GL PP P P++G++L++ K HL SQ+YG++L +R+GS V+V++
Sbjct: 37 KGLKSPPEPWGWPLLGHVLTL------GKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSR 90
Query: 198 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 368
++ IR+ V + F+GRPD + T+ + G+ L GP W RR L F
Sbjct: 91 LDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRLAQNALNTFSIA 150
Query: 369 ------NSRFMNVYIGEECEALV---QLRLADAGEPILVNQMFHITIVNILWRLVAGKRY 521
+S ++ ++ +E +AL+ Q +A G NQ+ +++ N++ + G+ +
Sbjct: 151 SDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVV-VSVANVIGAMCFGQHF 209
Query: 522 DLXDQRLKKLCSLVMRLFKLXDMSGGILNFLPFLXH 629
+ L + SG L+F P L +
Sbjct: 210 PESSDEMLSLVKNTHEFVETAS-SGNPLDFFPILRY 244
>AF182274-1|AAF13599.1| 516|Homo sapiens cytochrome P450-1A2
protein.
Length = 516
Score = 72.9 bits (171), Expect = 1e-12
Identities = 57/216 (26%), Positives = 102/216 (47%), Gaps = 12/216 (5%)
Frame = +3
Query: 18 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 197
+GL PP P P++G++L++ K HL SQ+YG++L +R+GS V+V++
Sbjct: 37 KGLKSPPEPWGWPLLGHVLTL------GKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSR 90
Query: 198 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 368
++ IR+ V + F+GRPD + T+ + G+ L GP W RR L F
Sbjct: 91 LDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRLAQNALNTFSIA 150
Query: 369 ------NSRFMNVYIGEECEALV---QLRLADAGEPILVNQMFHITIVNILWRLVAGKRY 521
+S ++ ++ +E AL+ Q +A G NQ+ +++ N++ + G+ +
Sbjct: 151 SDPASSSSCYLEEHVSKEAMALISRLQELMAGPGHFDPYNQVV-VSVANVIGAMCFGQHF 209
Query: 522 DLXDQRLKKLCSLVMRLFKLXDMSGGILNFLPFLXH 629
+ L + SG L+F P L +
Sbjct: 210 PESSDEMLSLVKNTHEFVETAS-SGNPLDFFPILRY 244
>L00389-1|AAA35738.1| 516|Homo sapiens protein ( Human cytochrome
P-450 4 gene, exon 7, and three Alu repeats in the 3'
flank. ).
Length = 516
Score = 71.7 bits (168), Expect = 2e-12
Identities = 56/216 (25%), Positives = 102/216 (47%), Gaps = 12/216 (5%)
Frame = +3
Query: 18 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 197
+GL PP P P++G++L++ K HL SQ+YG++L + +GS V+V++
Sbjct: 37 KGLKSPPEPWGWPLLGHVLTL------GKNPHLALSRMSQRYGDVLQISIGSTPVLVLSR 90
Query: 198 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 368
++ IR+ V + F+GRPD + T+ + G+ L GP W RR L F
Sbjct: 91 LDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRLAQNALNTFSIA 150
Query: 369 ------NSRFMNVYIGEECEALV---QLRLADAGEPILVNQMFHITIVNILWRLVAGKRY 521
+S ++ ++ +E +AL+ Q +A G NQ+ +++ N++ + G+ +
Sbjct: 151 SDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVV-VSVANVIGAMCFGQHF 209
Query: 522 DLXDQRLKKLCSLVMRLFKLXDMSGGILNFLPFLXH 629
+ L + SG L+F P L +
Sbjct: 210 PESSDEMLSLVKNTHEFVETAS-SGNPLDFFPILRY 244
>BC067427-1|AAH67427.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 71.3 bits (167), Expect = 3e-12
Identities = 56/216 (25%), Positives = 102/216 (47%), Gaps = 12/216 (5%)
Frame = +3
Query: 18 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 197
+GL PP P P++G++L++ K HL SQ+YG++L +R+ S V+V++
Sbjct: 37 KGLKSPPEPWGWPLLGHVLTL------GKNPHLALSRMSQRYGDVLQIRIDSTPVLVLSR 90
Query: 198 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 368
++ IR+ V + F+GRPD + T+ + G+ L GP W RR L F
Sbjct: 91 LDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRLAQNALNTFSIA 150
Query: 369 ------NSRFMNVYIGEECEALV---QLRLADAGEPILVNQMFHITIVNILWRLVAGKRY 521
+S ++ ++ +E +AL+ Q +A G NQ+ +++ N++ + G+ +
Sbjct: 151 SDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVV-VSVANVIGAMCFGQHF 209
Query: 522 DLXDQRLKKLCSLVMRLFKLXDMSGGILNFLPFLXH 629
+ L + SG L+F P L +
Sbjct: 210 PESSDEMLSLVKNTHEFVETAS-SGNPLDFFPILRY 244
>AB209492-1|BAD92729.1| 566|Homo sapiens Debrisoquine 4-hydroxylase
mutant allele variant protein.
Length = 566
Score = 60.1 bits (139), Expect(2) = 7e-12
Identities = 47/177 (26%), Positives = 78/177 (44%), Gaps = 5/177 (2%)
Frame = +3
Query: 135 QKYGNLLGLRLGSINVVVVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD 308
+++G++ L+L VVV+ G+ +RE V+ E RP + FG + VF
Sbjct: 133 RRFGDVFSLQLAWTPVVVLNGLAAVREAMVTRGEDTADRPPVPITQILGFGPRSQGVFLA 192
Query: 309 --GPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITI 482
GP W RRF + L+N G + + ++ EE L A+ + +
Sbjct: 193 RYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLC-AAFANHSDAPFAPTVSWTKP 251
Query: 483 VNILWRLVAGKRYDLXDQRLKKLCSLVMR-LFKLXDMSGGILNFLPFLXHFVPRLIG 650
N++ L G+R++ D R +L L L + +LN +P L H +P L G
Sbjct: 252 SNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 307
Score = 30.3 bits (65), Expect(2) = 7e-12
Identities = 15/32 (46%), Positives = 20/32 (62%), Gaps = 1/32 (3%)
Frame = +3
Query: 9 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKF 101
RR R Y PGP PLP +GNLL V +++ +
Sbjct: 62 RRQRWAARYSPGPLPLPGLGNLLHVDFQNTPY 93
>X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is 3rd
base in codon) protein.
Length = 448
Score = 70.1 bits (164), Expect = 7e-12
Identities = 49/160 (30%), Positives = 75/160 (46%), Gaps = 2/160 (1%)
Frame = +3
Query: 132 SQKYGNLLGLRLGSINVVVVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 305
S++YG + + LG VVV+ G + +RE V E F GR G T K G+VFS
Sbjct: 16 SERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGR--GEQATFDWVFKGYGVVFS 73
Query: 306 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIV 485
+G + RRF + L++FG R + I EE L+ G I T+
Sbjct: 74 NGERAKQLRRFSIATLRDFGVGKRGIEERIQEEAGFLIDALRGTGGANIDPTFFLSRTVS 133
Query: 486 NILWRLVAGKRYDLXDQRLKKLCSLVMRLFKLXDMSGGIL 605
N++ +V G R+D D+ L +++ +F+ S G L
Sbjct: 134 NVISSIVFGDRFDYKDKEFLSLLRMMLGIFQFTSTSTGQL 173
>BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family 2,
subfamily S, polypeptide 1 protein.
Length = 504
Score = 68.9 bits (161), Expect = 2e-11
Identities = 52/174 (29%), Positives = 80/174 (45%), Gaps = 3/174 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSIN-VVVVTGIELI 209
PPGPTPLP++GNLL + R + + + S+KYG + + LG VVV+ G E +
Sbjct: 33 PPGPTPLPLLGNLLQL----RPGALYSGLMRL-SKKYGPVFTIYLGPWRPVVVLVGQEAV 87
Query: 210 REV--SNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFM 383
RE E F GR G + G+ FS+G W + R+F + L++ G R
Sbjct: 88 REALGGQAEEFSGR--GTVAMLEGTFDGHGVFFSNGERWRQLRKFTMLALRDLGMGKREG 145
Query: 384 NVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLK 545
I E LV+ G P + + N++ L+ G R+ D+ +
Sbjct: 146 EELIQAEARCLVETFQGTEGRPFDPSLLLAQATSNVVCSLLFGLRFSYEDKEFQ 199
>AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein.
Length = 504
Score = 68.9 bits (161), Expect = 2e-11
Identities = 52/174 (29%), Positives = 80/174 (45%), Gaps = 3/174 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSIN-VVVVTGIELI 209
PPGPTPLP++GNLL + R + + + S+KYG + + LG VVV+ G E +
Sbjct: 33 PPGPTPLPLLGNLLQL----RPGALYSGLMRL-SKKYGPVFTIYLGPWRPVVVLVGQEAV 87
Query: 210 REV--SNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFM 383
RE E F GR G + G+ FS+G W + R+F + L++ G R
Sbjct: 88 REALGGQAEEFSGR--GTVAMLEGTFDGHGVFFSNGERWRQLRKFTMLALRDLGMGKREG 145
Query: 384 NVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLK 545
I E LV+ G P + + N++ L+ G R+ D+ +
Sbjct: 146 EELIQAEARCLVETFQGTEGRPFDPSLLLAQATSNVVCSLLFGLRFSYEDKEFQ 199
>AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens
cDNA FLJ14699 fis, clone NT2RP2006571, moderately
similar to CYTOCHROME P450 2G1 (EC 1.14.14.1). ).
Length = 564
Score = 68.9 bits (161), Expect = 2e-11
Identities = 52/174 (29%), Positives = 80/174 (45%), Gaps = 3/174 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSIN-VVVVTGIELI 209
PPGPTPLP++GNLL + R + + + S+KYG + + LG VVV+ G E +
Sbjct: 33 PPGPTPLPLLGNLLQL----RPGALYSGLMRL-SKKYGPVFTIYLGPWRPVVVLVGQEAV 87
Query: 210 REV--SNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFM 383
RE E F GR G + G+ FS+G W + R+F + L++ G R
Sbjct: 88 REALGGQAEEFSGR--GTVAMLEGTFDGHGVFFSNGERWRQLRKFTMLALRDLGMGKREG 145
Query: 384 NVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLK 545
I E LV+ G P + + N++ L+ G R+ D+ +
Sbjct: 146 EELIQAEARCLVETFQGTEGRPFDPSLLLAQATSNVVCSLLFGLRFSYEDKEFQ 199
>AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1
protein.
Length = 504
Score = 68.9 bits (161), Expect = 2e-11
Identities = 52/174 (29%), Positives = 80/174 (45%), Gaps = 3/174 (1%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSIN-VVVVTGIELI 209
PPGPTPLP++GNLL + R + + + S+KYG + + LG VVV+ G E +
Sbjct: 33 PPGPTPLPLLGNLLQL----RPGALYSGLMRL-SKKYGPVFTIYLGPWRPVVVLVGQEAV 87
Query: 210 REV--SNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFM 383
RE E F GR G + G+ FS+G W + R+F + L++ G R
Sbjct: 88 REALGGQAEEFSGR--GTVAMLEGTFDGHGVFFSNGERWRQLRKFTMLALRDLGMGKREG 145
Query: 384 NVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLK 545
I E LV+ G P + + N++ L+ G R+ D+ +
Sbjct: 146 EELIQAEARCLVETFQGTEGRPFDPSLLLAQATSNVVCSLLFGLRFSYEDKEFQ 199
>BC025761-1|AAH25761.2| 490|Homo sapiens cytochrome P450, family 2,
subfamily W, polypeptide 1 protein.
Length = 490
Score = 68.1 bits (159), Expect = 3e-11
Identities = 55/202 (27%), Positives = 89/202 (44%), Gaps = 4/202 (1%)
Frame = +3
Query: 30 YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELI 209
+PPGP PLP+VGNL + + L S++YG + + LG VV+TG E +
Sbjct: 31 WPPGPRPLPLVGNLHLLRLSQQDRSLMEL-----SERYGPVFTVHLGRQKTVVLTGFEAV 85
Query: 210 REV---SNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRF 380
+E +E+ + P F ++ G G+ FS G W R+F ++ L + G
Sbjct: 86 KEALAGPGQELADRPPIAIFQLIQRGG---GIFFSSGARWRAARQFTVRALHSLGVGREP 142
Query: 381 MNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCSL 560
+ I +E + L G P + + NI + L+ G+R+D D L L
Sbjct: 143 VADKILQELKCLSGQLDGYRGRPFPL-ALLGWAPSNITFALLFGRRFDYRDPVFVSLLGL 201
Query: 561 VMRLFKLXDMSG-GILNFLPFL 623
+ + L G + N P+L
Sbjct: 202 IDEVMVLLGSPGLQLFNVYPWL 223
>L07093-1|AAA36660.1| 468|Homo sapiens cytochrome P450 protein.
Length = 468
Score = 67.3 bits (157), Expect = 5e-11
Identities = 44/145 (30%), Positives = 66/145 (45%), Gaps = 2/145 (1%)
Frame = +3
Query: 123 QSWSQKYGNLLGLRLGSINVVVVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGL 296
Q S+ YG + L G +VV+ G E+++E + E F GR G F + G+
Sbjct: 33 QQLSKIYGPVFTLYFGLERMVVLHGYEVVKEALIDLGEEFSGR--GHFPLAERANRGFGI 90
Query: 297 VFSDGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHI 476
VFS+G W RRF L L+NFG R + + EE LV+ P +
Sbjct: 91 VFSNGKRWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGC 150
Query: 477 TIVNILWRLVAGKRYDLXDQRLKKL 551
N++ ++ KR+D DQ+ L
Sbjct: 151 APCNVICSIIFQKRFDYKDQQFLNL 175
>M33189-1|AAA35737.1| 500|Homo sapiens protein ( Human debrisoquine
4-hydroxylase mutant allele (CYP2D6-MA1) gene, complete
cds. ).
Length = 500
Score = 59.3 bits (137), Expect = 1e-08
Identities = 63/227 (27%), Positives = 98/227 (43%), Gaps = 13/227 (5%)
Frame = +3
Query: 9 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 185
RR R Y PGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYSPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 186 VVTGIELIRE--VSNREVFEGRP-----DGFFYTMRSFGKKLGLVFSDGPTWHRTRR--- 335
V+ G+ +RE V+ E RP + RS GK+ G+ G W R R
Sbjct: 80 VLNGLAAVREAMVTRGEDTADRPPVPITQILGFGPRSQGKQRGV---PGALWARVARAEA 136
Query: 336 FVLKYLKNFGYNSRFMNVYIGEECEALVQLRLAD-AGEPILVNQMFHITIVNILWRLVAG 512
+ +L G +G+ L RL P N + + N++ L G
Sbjct: 137 LLRLHLAQLGPGQEVAGA-VGDRGGRLPLCRLRQPLRRPFRPNGLLDKAVSNVIASLTCG 195
Query: 513 KRYDLXDQRLKKLCSLVMR-LFKLXDMSGGILNFLPFLXHFVPRLIG 650
+R++ D R +L L L + +LN +P L H +P L G
Sbjct: 196 RRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 241
>M24499-1|AAA36403.1| 373|Homo sapiens cytochrome P450db1 protein.
Length = 373
Score = 57.6 bits (133), Expect = 4e-08
Identities = 32/115 (27%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Frame = +3
Query: 309 GPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVN 488
GP W RRF + L+N G + + ++ EE L +G P N + + N
Sbjct: 1 GPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSN 60
Query: 489 ILWRLVAGKRYDLXDQRLKKLCSLVMR-LFKLXDMSGGILNFLPFLXHFVPRLIG 650
++ L G+R++ D R +L L L + +LN +P L H +P L G
Sbjct: 61 VIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 114
>U56438-1|AAC50809.1| 543|Homo sapiens dioxin-inducible cytochrome
P450 protein.
Length = 543
Score = 53.6 bits (123), Expect = 7e-07
Identities = 52/238 (21%), Positives = 103/238 (43%), Gaps = 9/238 (3%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 188
RR + PPGP P++GN +V + HL + +++YG++ +RLGS +VV
Sbjct: 43 RRRQLRSAPPGPFAWPLIGNAAAV------GQAAHLSFARLARRYGDVFQIRLGSCPIVV 96
Query: 189 VTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNF 362
+ G I + V F RP + + S G+ + W RR ++NF
Sbjct: 97 LNGERAIHQALVQQGSAFADRPAFASFRVVSGGRSMAFGHY-SEHWKVQRRAAHSMMRNF 155
Query: 363 ----GYNSRFMNVYIGEECEALVQLRLADAGEPILVN--QMFHITIVNILWRLVAGKRYD 524
+ + + ++ E LV L + + + ++ + + + N++ + G RY
Sbjct: 156 FTRQPRSRQVLEGHVLSEARELVALLVRGSADGAFLDPRPLTVVAVANVMSAVCFGCRYS 215
Query: 525 LXDQRLKKLCSLVMRLFKLXDMSGGILNFLPFLXHFV-PRLIGFTELQXIHNALHQYL 695
D ++L S F +G +++ +P+L +F P F E + ++ ++
Sbjct: 216 HDDPEFRELLS-HNEEFGRTVGAGSLVDVMPWLQYFPNPVRTVFREFEQLNRNFSNFI 272
>U03688-1|AAA19567.1| 543|Homo sapiens cytochrome P450 protein.
Length = 543
Score = 53.6 bits (123), Expect = 7e-07
Identities = 52/238 (21%), Positives = 103/238 (43%), Gaps = 9/238 (3%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 188
RR + PPGP P++GN +V + HL + +++YG++ +RLGS +VV
Sbjct: 43 RRRQLRSAPPGPFAWPLIGNAAAV------GQAAHLSFARLARRYGDVFQIRLGSCPIVV 96
Query: 189 VTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNF 362
+ G I + V F RP + + S G+ + W RR ++NF
Sbjct: 97 LNGERAIHQALVQQGSAFADRPAFASFRVVSGGRSMAFGHY-SEHWKVQRRAAHSMMRNF 155
Query: 363 ----GYNSRFMNVYIGEECEALVQLRLADAGEPILVN--QMFHITIVNILWRLVAGKRYD 524
+ + + ++ E LV L + + + ++ + + + N++ + G RY
Sbjct: 156 FTRQPRSRQVLEGHVLSEARELVALLVRGSADGAFLDPRPLTVVAVANVMSAVCFGCRYS 215
Query: 525 LXDQRLKKLCSLVMRLFKLXDMSGGILNFLPFLXHFV-PRLIGFTELQXIHNALHQYL 695
D ++L S F +G +++ +P+L +F P F E + ++ ++
Sbjct: 216 HDDPEFRELLS-HNEEFGRTVGAGSLVDVMPWLQYFPNPVRTVFREFEQLNRNFSNFI 272
>DQ359216-1|ABC95161.1| 347|Homo sapiens dioxin-inducible
cytochrome P450 protein.
Length = 347
Score = 53.6 bits (123), Expect = 7e-07
Identities = 52/238 (21%), Positives = 103/238 (43%), Gaps = 9/238 (3%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 188
RR + PPGP P++GN +V + HL + +++YG++ +RLGS +VV
Sbjct: 43 RRRQLRSAPPGPFAWPLIGNAAAV------GQAAHLSFARLARRYGDVFQIRLGSCPIVV 96
Query: 189 VTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNF 362
+ G I + V F RP + + S G+ + W RR ++NF
Sbjct: 97 LNGERAIHQALVQQGSAFADRPAFASFRVVSGGRSMAFGHY-SEHWKVQRRAAHSMMRNF 155
Query: 363 ----GYNSRFMNVYIGEECEALVQLRLADAGEPILVN--QMFHITIVNILWRLVAGKRYD 524
+ + + ++ E LV L + + + ++ + + + N++ + G RY
Sbjct: 156 FTRQPRSRQVLEGHVLSEARELVALLVRGSADGAFLDPRPLTVVAVANVMSAVCFGCRYS 215
Query: 525 LXDQRLKKLCSLVMRLFKLXDMSGGILNFLPFLXHFV-PRLIGFTELQXIHNALHQYL 695
D ++L S F +G +++ +P+L +F P F E + ++ ++
Sbjct: 216 HDDPEFRELLS-HNEEFGRTVGAGSLVDVMPWLQYFPNPVRTVFREFEQLNRNFSNFI 272
>BT019979-1|AAV38782.1| 543|Homo sapiens cytochrome P450, family 1,
subfamily B, polypeptide 1 protein.
Length = 543
Score = 53.6 bits (123), Expect = 7e-07
Identities = 52/238 (21%), Positives = 103/238 (43%), Gaps = 9/238 (3%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 188
RR + PPGP P++GN +V + HL + +++YG++ +RLGS +VV
Sbjct: 43 RRRQLRSAPPGPFAWPLIGNAAAV------GQAAHLSFARLARRYGDVFQIRLGSCPIVV 96
Query: 189 VTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNF 362
+ G I + V F RP + + S G+ + W RR ++NF
Sbjct: 97 LNGERAIHQALVQQGSAFADRPAFASFRVVSGGRSMAFGHY-SEHWKVQRRAAHSMMRNF 155
Query: 363 ----GYNSRFMNVYIGEECEALVQLRLADAGEPILVN--QMFHITIVNILWRLVAGKRYD 524
+ + + ++ E LV L + + + ++ + + + N++ + G RY
Sbjct: 156 FTRQPRSRQVLEGHVLSEARELVALLVRGSADGAFLDPRPLTVVAVANVMSAVCFGCRYS 215
Query: 525 LXDQRLKKLCSLVMRLFKLXDMSGGILNFLPFLXHFV-PRLIGFTELQXIHNALHQYL 695
D ++L S F +G +++ +P+L +F P F E + ++ ++
Sbjct: 216 HDDPEFRELLS-HNEEFGRTVGAGSLVDVMPWLQYFPNPVRTVFREFEQLNRNFSNFI 272
>BC012049-1|AAH12049.1| 543|Homo sapiens cytochrome P450, family 1,
subfamily B, polypeptide 1 protein.
Length = 543
Score = 53.6 bits (123), Expect = 7e-07
Identities = 52/238 (21%), Positives = 103/238 (43%), Gaps = 9/238 (3%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 188
RR + PPGP P++GN +V + HL + +++YG++ +RLGS +VV
Sbjct: 43 RRRQLRSAPPGPFAWPLIGNAAAV------GQAAHLSFARLARRYGDVFQIRLGSCPIVV 96
Query: 189 VTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNF 362
+ G I + V F RP + + S G+ + W RR ++NF
Sbjct: 97 LNGERAIHQALVQQGSAFADRPAFASFRVVSGGRSMAFGHY-SEHWKVQRRAAHSMMRNF 155
Query: 363 ----GYNSRFMNVYIGEECEALVQLRLADAGEPILVN--QMFHITIVNILWRLVAGKRYD 524
+ + + ++ E LV L + + + ++ + + + N++ + G RY
Sbjct: 156 FTRQPRSRQVLEGHVLSEARELVALLVRGSADGAFLDPRPLTVVAVANVMSAVCFGCRYS 215
Query: 525 LXDQRLKKLCSLVMRLFKLXDMSGGILNFLPFLXHFV-PRLIGFTELQXIHNALHQYL 695
D ++L S F +G +++ +P+L +F P F E + ++ ++
Sbjct: 216 HDDPEFRELLS-HNEEFGRTVGAGSLVDVMPWLQYFPNPVRTVFREFEQLNRNFSNFI 272
>AY393998-1|AAQ87875.1| 543|Homo sapiens cytochrome P450, family 1,
subfamily B, polypeptide 1 protein.
Length = 543
Score = 53.6 bits (123), Expect = 7e-07
Identities = 52/238 (21%), Positives = 103/238 (43%), Gaps = 9/238 (3%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 188
RR + PPGP P++GN +V + HL + +++YG++ +RLGS +VV
Sbjct: 43 RRRQLRSAPPGPFAWPLIGNAAAV------GQAAHLSFARLARRYGDVFQIRLGSCPIVV 96
Query: 189 VTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNF 362
+ G I + V F RP + + S G+ + W RR ++NF
Sbjct: 97 LNGERAIHQALVQQGSAFADRPAFASFRVVSGGRSMAFGHY-SEHWKVQRRAAHSMMRNF 155
Query: 363 ----GYNSRFMNVYIGEECEALVQLRLADAGEPILVN--QMFHITIVNILWRLVAGKRYD 524
+ + + ++ E LV L + + + ++ + + + N++ + G RY
Sbjct: 156 FTRQPRSRQVLEGHVLSEARELVALLVRGSADGAFLDPRPLTVVAVANVMSAVCFGCRYS 215
Query: 525 LXDQRLKKLCSLVMRLFKLXDMSGGILNFLPFLXHFV-PRLIGFTELQXIHNALHQYL 695
D ++L S F +G +++ +P+L +F P F E + ++ ++
Sbjct: 216 HDDPEFRELLS-HNEEFGRTVGAGSLVDVMPWLQYFPNPVRTVFREFEQLNRNFSNFI 272
>AF450132-1|AAM50512.1| 543|Homo sapiens cytochrome P450 CYP1B1
protein.
Length = 543
Score = 53.6 bits (123), Expect = 7e-07
Identities = 52/238 (21%), Positives = 103/238 (43%), Gaps = 9/238 (3%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 188
RR + PPGP P++GN +V + HL + +++YG++ +RLGS +VV
Sbjct: 43 RRRQLRSAPPGPFAWPLIGNAAAV------GQAAHLSFARLARRYGDVFQIRLGSCPIVV 96
Query: 189 VTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNF 362
+ G I + V F RP + + S G+ + W RR ++NF
Sbjct: 97 LNGERAIHQALVQQGSAFADRPAFASFRVVSGGRSMAFGHY-SEHWKVQRRAAHSMMRNF 155
Query: 363 ----GYNSRFMNVYIGEECEALVQLRLADAGEPILVN--QMFHITIVNILWRLVAGKRYD 524
+ + + ++ E LV L + + + ++ + + + N++ + G RY
Sbjct: 156 FTRQPRSRQVLEGHVLSEARELVALLVRGSADGAFLDPRPLTVVAVANVMSAVCFGCRYS 215
Query: 525 LXDQRLKKLCSLVMRLFKLXDMSGGILNFLPFLXHFV-PRLIGFTELQXIHNALHQYL 695
D ++L S F +G +++ +P+L +F P F E + ++ ++
Sbjct: 216 HDDPEFRELLS-HNEEFGRTVGAGSLVDVMPWLQYFPNPVRTVFREFEQLNRNFSNFI 272
>AC009229-2|AAY15039.1| 543|Homo sapiens unknown protein.
Length = 543
Score = 53.6 bits (123), Expect = 7e-07
Identities = 52/238 (21%), Positives = 103/238 (43%), Gaps = 9/238 (3%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 188
RR + PPGP P++GN +V + HL + +++YG++ +RLGS +VV
Sbjct: 43 RRRQLRSAPPGPFAWPLIGNAAAV------GQAAHLSFARLARRYGDVFQIRLGSCPIVV 96
Query: 189 VTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNF 362
+ G I + V F RP + + S G+ + W RR ++NF
Sbjct: 97 LNGERAIHQALVQQGSAFADRPAFASFRVVSGGRSMAFGHY-SEHWKVQRRAAHSMMRNF 155
Query: 363 ----GYNSRFMNVYIGEECEALVQLRLADAGEPILVN--QMFHITIVNILWRLVAGKRYD 524
+ + + ++ E LV L + + + ++ + + + N++ + G RY
Sbjct: 156 FTRQPRSRQVLEGHVLSEARELVALLVRGSADGAFLDPRPLTVVAVANVMSAVCFGCRYS 215
Query: 525 LXDQRLKKLCSLVMRLFKLXDMSGGILNFLPFLXHFV-PRLIGFTELQXIHNALHQYL 695
D ++L S F +G +++ +P+L +F P F E + ++ ++
Sbjct: 216 HDDPEFRELLS-HNEEFGRTVGAGSLVDVMPWLQYFPNPVRTVFREFEQLNRNFSNFI 272
>BT020001-1|AAV38804.1| 543|Homo sapiens cytochrome P450, family 1,
subfamily B, polypeptide 1 protein.
Length = 543
Score = 52.8 bits (121), Expect = 1e-06
Identities = 52/238 (21%), Positives = 103/238 (43%), Gaps = 9/238 (3%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 188
RR + PPGP P++GN +V + HL + +++YG++ +RLGS +VV
Sbjct: 43 RRRQLRSAPPGPFAWPLIGNAAAV------GQAAHLSFARLARRYGDVFQIRLGSCPIVV 96
Query: 189 VTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNF 362
+ G I + V F RP + + S G+ + W RR ++NF
Sbjct: 97 LNGERAIHQALVQQGSAFADRPAFASFRVVSGGRSMAFGHY-SEHWKVQRRAAHSMMRNF 155
Query: 363 ----GYNSRFMNVYIGEECEALVQLRLADAGEPILVN--QMFHITIVNILWRLVAGKRYD 524
+ + + ++ E LV L + + + ++ + + + N++ + G RY
Sbjct: 156 FTRQPRSRQVLEGHVLSEARELVALLVRGSADGAFLDPRPLTVVAMANVMSAVCFGCRYS 215
Query: 525 LXDQRLKKLCSLVMRLFKLXDMSGGILNFLPFLXHFV-PRLIGFTELQXIHNALHQYL 695
D ++L S F +G +++ +P+L +F P F E + ++ ++
Sbjct: 216 HDDPEFRELLS-HNEEFGRTVGAGSLVDVMPWLQYFPNPVRTVFREFEQLNRNFSSFI 272
>M21940-1|AAA52159.1| 383|Homo sapiens CYP2C protein.
Length = 383
Score = 51.6 bits (118), Expect = 3e-06
Identities = 32/116 (27%), Positives = 50/116 (43%), Gaps = 2/116 (1%)
Frame = +3
Query: 291 GLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMF 470
G+VFS+G W RRF L L+NFG R + + EE LV+ P +
Sbjct: 4 GIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFIL 63
Query: 471 HITIVNILWRLVAGKRYDLXDQRLKKLCSLVMRLFKLXDMSGGIL--NFLPFLXHF 632
N++ ++ KR+D DQ+ L + K+ + NF P + +F
Sbjct: 64 GCAPCNVICSIIFHKRFDYKDQQFLNLMEKLNENIKILSSPWIQICNNFSPIIDYF 119
>AK000366-1|BAA91114.1| 408|Homo sapiens protein ( Homo sapiens
cDNA FLJ20359 fis, clone HEP16626. ).
Length = 408
Score = 51.6 bits (118), Expect = 3e-06
Identities = 43/168 (25%), Positives = 73/168 (43%), Gaps = 4/168 (2%)
Frame = +3
Query: 132 SQKYGNLLGLRLGSINVVVVTGIELIREV---SNREVFEGRPDGFFYTMRSFGKKLGLVF 302
S++YG + + LG VV+TG E ++E +E+ + P F ++ G G+ F
Sbjct: 4 SERYGPVFTVHLGRQKTVVLTGFEAVKEALAGPGQELADRPPIAIFQLIQRGG---GIFF 60
Query: 303 SDGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITI 482
S G W R+F ++ L + G + I +E + L G P + +
Sbjct: 61 SSGARWRAARQFTVRALHSLGVGREPVADKILQELKCLSGQLDGYRGRPFPL-ALLGWAP 119
Query: 483 VNILWRLVAGKRYDLXDQRLKKLCSLVMRLFKLXDMSG-GILNFLPFL 623
NI + L+ G+R+D D L L+ + L G + N P+L
Sbjct: 120 SNITFALLFGRRFDYRDPVFVSLLGLIDEVMVLLGSPGLQLFNVHPWL 167
>M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 50.8 bits (116), Expect = 5e-06
Identities = 45/181 (24%), Positives = 77/181 (42%), Gaps = 3/181 (1%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 188
RR G YP LP+VG+L + R H+ ++ +KYG + +R+G+ V+
Sbjct: 20 RRWPGAKYPKSLLSLPLVGSLPFL---PRHGHMHNNFFKL-QKKYGPIYSVRMGTKTTVI 75
Query: 189 VTGIELIREV--SNREVFEGRPDGFFYTMRSFGKKLGLVFSD-GPTWHRTRRFVLKYLKN 359
V +L +EV + F GRP + S +K G+ F+D G W RR +
Sbjct: 76 VGHHQLAKEVLIKKGKDFSGRPQMATLDIASNNRK-GIAFADSGAHWQLHRRLAMATFAL 134
Query: 360 FGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 539
F + + I +E L + G+ I ++ + + N++ + Y D
Sbjct: 135 FKDGDQKLEKIICQEISTLCDMLATHNGQSIDISFPVFVAVTNVISLICFNTSYKNGDPE 194
Query: 540 L 542
L
Sbjct: 195 L 195
>M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 50.8 bits (116), Expect = 5e-06
Identities = 45/181 (24%), Positives = 77/181 (42%), Gaps = 3/181 (1%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 188
RR G YP LP+VG+L + R H+ ++ +KYG + +R+G+ V+
Sbjct: 20 RRWPGAKYPKSLLSLPLVGSLPFL---PRHGHMHNNFFKL-QKKYGPIYSVRMGTKTTVI 75
Query: 189 VTGIELIREV--SNREVFEGRPDGFFYTMRSFGKKLGLVFSD-GPTWHRTRRFVLKYLKN 359
V +L +EV + F GRP + S +K G+ F+D G W RR +
Sbjct: 76 VGHHQLAKEVLIKKGKDFSGRPQMATLDIASNNRK-GIAFADSGAHWQLHRRLAMATFAL 134
Query: 360 FGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 539
F + + I +E L + G+ I ++ + + N++ + Y D
Sbjct: 135 FKDGDQKLEKIICQEISTLCDMLATHNGQSIDISFPVFVAVTNVISLICFNTSYKNGDPE 194
Query: 540 L 542
L
Sbjct: 195 L 195
>M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 50.4 bits (115), Expect = 6e-06
Identities = 45/181 (24%), Positives = 77/181 (42%), Gaps = 3/181 (1%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 188
RR G YP LP+VG+L + R H+ ++ +KYG + +R+G+ V+
Sbjct: 20 RRCPGAKYPKSLLSLPLVGSLPFL---PRHGHMHNNFFKL-QKKYGPIYSVRMGTKTTVI 75
Query: 189 VTGIELIREV--SNREVFEGRPDGFFYTMRSFGKKLGLVFSD-GPTWHRTRRFVLKYLKN 359
V +L +EV + F GRP + S +K G+ F+D G W RR +
Sbjct: 76 VGHHQLAKEVLIKKGKDFSGRPQMATLDIASNNRK-GIAFADSGAHWQLHRRLAMATFAL 134
Query: 360 FGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 539
F + + I +E L + G+ I ++ + + N++ + Y D
Sbjct: 135 FKDGDQKLEKIICQEISTLCDMLATHNGQSIDISFPVFVAVTNVISLICFNTSYKNGDPE 194
Query: 540 L 542
L
Sbjct: 195 L 195
>DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 50.4 bits (115), Expect = 6e-06
Identities = 45/181 (24%), Positives = 77/181 (42%), Gaps = 3/181 (1%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 188
RR G YP LP+VG+L + R H+ ++ +KYG + +R+G+ V+
Sbjct: 20 RRCPGAKYPKSLLSLPLVGSLPFL---PRHGHMHNNFFKL-QKKYGPIYSVRMGTKTTVI 75
Query: 189 VTGIELIREV--SNREVFEGRPDGFFYTMRSFGKKLGLVFSD-GPTWHRTRRFVLKYLKN 359
V +L +EV + F GRP + S +K G+ F+D G W RR +
Sbjct: 76 VGHHQLAKEVLIKKGKDFSGRPQMATLDIASNNRK-GIAFADSGAHWQLHRRLAMATFAL 134
Query: 360 FGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 539
F + + I +E L + G+ I ++ + + N++ + Y D
Sbjct: 135 FKDGDQKLEKIICQEISTLCDMLATHNGQSIDISFPVFVAVTNVISLICFNTSYKNGDPE 194
Query: 540 L 542
L
Sbjct: 195 L 195
>BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 50.4 bits (115), Expect = 6e-06
Identities = 45/181 (24%), Positives = 77/181 (42%), Gaps = 3/181 (1%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 188
RR G YP LP+VG+L + R H+ ++ +KYG + +R+G+ V+
Sbjct: 20 RRCPGAKYPKSLLSLPLVGSLPFL---PRHGHMHNNFFKL-QKKYGPIYSVRMGTKTTVI 75
Query: 189 VTGIELIREV--SNREVFEGRPDGFFYTMRSFGKKLGLVFSD-GPTWHRTRRFVLKYLKN 359
V +L +EV + F GRP + S +K G+ F+D G W RR +
Sbjct: 76 VGHHQLAKEVLIKKGKDFSGRPQMATLDIASNNRK-GIAFADSGAHWQLHRRLAMATFAL 134
Query: 360 FGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 539
F + + I +E L + G+ I ++ + + N++ + Y D
Sbjct: 135 FKDGDQKLEKIICQEISTLCDMLATHNGQSIDISFPVFVAVTNVISLICFNTSYKNGDPE 194
Query: 540 L 542
L
Sbjct: 195 L 195
>BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 50.4 bits (115), Expect = 6e-06
Identities = 45/181 (24%), Positives = 77/181 (42%), Gaps = 3/181 (1%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 188
RR G YP LP+VG+L + R H+ ++ +KYG + +R+G+ V+
Sbjct: 20 RRCPGAKYPKSLLSLPLVGSLPFL---PRHGHMHNNFFKL-QKKYGPIYSVRMGTKTTVI 75
Query: 189 VTGIELIREV--SNREVFEGRPDGFFYTMRSFGKKLGLVFSD-GPTWHRTRRFVLKYLKN 359
V +L +EV + F GRP + S +K G+ F+D G W RR +
Sbjct: 76 VGHHQLAKEVLIKKGKDFSGRPQMATLDIASNNRK-GIAFADSGAHWQLHRRLAMATFAL 134
Query: 360 FGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 539
F + + I +E L + G+ I ++ + + N++ + Y D
Sbjct: 135 FKDGDQKLEKIICQEISTLCDMLATHNGQSIDISFPVFVAVTNVISLICFNTSYKNGDPE 194
Query: 540 L 542
L
Sbjct: 195 L 195
>BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 50.4 bits (115), Expect = 6e-06
Identities = 45/181 (24%), Positives = 77/181 (42%), Gaps = 3/181 (1%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 188
RR G YP LP+VG+L + R H+ ++ +KYG + +R+G+ V+
Sbjct: 20 RRCPGAKYPKSLLSLPLVGSLPFL---PRHGHMHNNFFKL-QKKYGPIYSVRMGTKTTVI 75
Query: 189 VTGIELIREV--SNREVFEGRPDGFFYTMRSFGKKLGLVFSD-GPTWHRTRRFVLKYLKN 359
V +L +EV + F GRP + S +K G+ F+D G W RR +
Sbjct: 76 VGHHQLAKEVLIKKGKDFSGRPQMATLDIASNNRK-GIAFADSGAHWQLHRRLAMATFAL 134
Query: 360 FGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 539
F + + I +E L + G+ I ++ + + N++ + Y D
Sbjct: 135 FKDGDQKLEKIICQEISTLCDMLATHNGQSIDISFPVFVAVTNVISLICFNTSYKNGDPE 194
Query: 540 L 542
L
Sbjct: 195 L 195
>AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 50.4 bits (115), Expect = 6e-06
Identities = 45/181 (24%), Positives = 77/181 (42%), Gaps = 3/181 (1%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 188
RR G YP LP+VG+L + R H+ ++ +KYG + +R+G+ V+
Sbjct: 20 RRCPGAKYPKSLLSLPLVGSLPFL---PRHGHMHNNFFKL-QKKYGPIYSVRMGTKTTVI 75
Query: 189 VTGIELIREV--SNREVFEGRPDGFFYTMRSFGKKLGLVFSD-GPTWHRTRRFVLKYLKN 359
V +L +EV + F GRP + S +K G+ F+D G W RR +
Sbjct: 76 VGHHQLAKEVLIKKGKDFSGRPQMATLDIASNNRK-GIAFADSGAHWQLHRRLAMATFAL 134
Query: 360 FGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 539
F + + I +E L + G+ I ++ + + N++ + Y D
Sbjct: 135 FKDGDQKLEKIICQEISTLCDMLATHNGQSIDISFPVFVAVTNVISLICFNTSYKNGDPE 194
Query: 540 L 542
L
Sbjct: 195 L 195
>M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 50.0 bits (114), Expect = 8e-06
Identities = 45/181 (24%), Positives = 77/181 (42%), Gaps = 3/181 (1%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 188
RR G YP LP+VG+L + R H+ ++ +KYG + +R+G+ V+
Sbjct: 20 RRCPGAKYPKSLLSLPLVGSLPFL---PRHGHMHNNFFKL-QKKYGPIYSVRMGTKTTVI 75
Query: 189 VTGIELIREV--SNREVFEGRPDGFFYTMRSFGKKLGLVFSD-GPTWHRTRRFVLKYLKN 359
V +L +EV + F GRP + S +K G+ F+D G W RR +
Sbjct: 76 VGHHQLAKEVLIKKGKDFSGRPQMATLDIASNNRK-GIAFADSGAHWQLHRRLAMATFAL 134
Query: 360 FGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 539
F + + I +E L + G+ I ++ + + N++ + Y D
Sbjct: 135 FKDGDQKLEKIICQEISTLSDMLATHNGQSIDISFPVFVAVTNVISLICFNTSYKNGDPE 194
Query: 540 L 542
L
Sbjct: 195 L 195
>BC109084-1|AAI09085.1| 448|Homo sapiens CYP24A1 protein protein.
Length = 448
Score = 46.8 bits (106), Expect = 8e-05
Identities = 34/115 (29%), Positives = 53/115 (46%), Gaps = 5/115 (4%)
Frame = +3
Query: 36 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 215
PGPT P++G+LL +LW+ K H + + + +KYG + ++LGS V + L+
Sbjct: 59 PGPTSWPLLGSLLQILWKGGLKKQHDTLVE-YHKKYGKIFRMKLGSFESVHLGSPCLLEA 117
Query: 216 VSNREV-----FEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFG 365
+ E E +P + R G GL+ +G W R R K L G
Sbjct: 118 LYRTESAYPQRLEIKPWKAYRDYRKEG--YGLLILEGEDWQRVRSAFQKKLMKPG 170
>BC109083-1|AAI09084.1| 448|Homo sapiens CYP24A1 protein protein.
Length = 448
Score = 46.8 bits (106), Expect = 8e-05
Identities = 34/115 (29%), Positives = 53/115 (46%), Gaps = 5/115 (4%)
Frame = +3
Query: 36 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 215
PGPT P++G+LL +LW+ K H + + + +KYG + ++LGS V + L+
Sbjct: 59 PGPTSWPLLGSLLQILWKGGLKKQHDTLVE-YHKKYGKIFRMKLGSFESVHLGSPCLLEA 117
Query: 216 VSNREV-----FEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFG 365
+ E E +P + R G GL+ +G W R R K L G
Sbjct: 118 LYRTESAYPQRLEIKPWKAYRDYRKEG--YGLLILEGEDWQRVRSAFQKKLMKPG 170
>AL138805-3|CAM27343.1| 448|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 448
Score = 46.8 bits (106), Expect = 8e-05
Identities = 34/115 (29%), Positives = 53/115 (46%), Gaps = 5/115 (4%)
Frame = +3
Query: 36 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 215
PGPT P++G+LL +LW+ K H + + + +KYG + ++LGS V + L+
Sbjct: 59 PGPTSWPLLGSLLQILWKGGLKKQHDTLVE-YHKKYGKIFRMKLGSFESVHLGSPCLLEA 117
Query: 216 VSNREV-----FEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFG 365
+ E E +P + R G GL+ +G W R R K L G
Sbjct: 118 LYRTESAYPQRLEIKPWKAYRDYRKEG--YGLLILEGEDWQRVRSAFQKKLMKPG 170
>AL138805-2|CAB91829.1| 514|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 514
Score = 46.8 bits (106), Expect = 8e-05
Identities = 34/115 (29%), Positives = 53/115 (46%), Gaps = 5/115 (4%)
Frame = +3
Query: 36 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 215
PGPT P++G+LL +LW+ K H + + + +KYG + ++LGS V + L+
Sbjct: 59 PGPTSWPLLGSLLQILWKGGLKKQHDTLVE-YHKKYGKIFRMKLGSFESVHLGSPCLLEA 117
Query: 216 VSNREV-----FEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFG 365
+ E E +P + R G GL+ +G W R R K L G
Sbjct: 118 LYRTESAYPQRLEIKPWKAYRDYRKEG--YGLLILEGEDWQRVRSAFQKKLMKPG 170
>L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3
24-hydroxylase protein.
Length = 513
Score = 46.4 bits (105), Expect = 1e-04
Identities = 32/112 (28%), Positives = 53/112 (47%), Gaps = 2/112 (1%)
Frame = +3
Query: 36 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 215
PGPT P++ +LL +LW+ K H + + + +KYG + ++LGS V + L+
Sbjct: 59 PGPTSWPLLASLLQILWKGGLKKQHDTLVE-YHKKYGKIFRMKLGSFESVHLGSPCLLEA 117
Query: 216 VSNREVFEGRPD-GFFYTMRSFGKK-LGLVFSDGPTWHRTRRFVLKYLKNFG 365
+ E R + + R + K+ GL+ +G W R R K L G
Sbjct: 118 LYRTESVPQRLEIKPWKAYRDYRKEGYGLLILEGEDWQRVRSAFQKKLMKPG 169
>CR456430-1|CAG30316.1| 446|Homo sapiens CYP2D6 protein.
Length = 446
Score = 45.6 bits (103), Expect = 2e-04
Identities = 32/96 (33%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Frame = +3
Query: 9 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 185
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 186 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKK 287
V+ G+ +RE V++ E RP + FG +
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPR 115
Score = 33.5 bits (73), Expect = 0.76
Identities = 20/71 (28%), Positives = 32/71 (45%), Gaps = 1/71 (1%)
Frame = +3
Query: 441 GEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCSLVMR-LFKLXDMSGGILNFLP 617
G P N + + N++ L G+R++ D R +L L L + +LN +P
Sbjct: 118 GRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVP 177
Query: 618 FLXHFVPRLIG 650
L H +P L G
Sbjct: 178 VLLH-IPALAG 187
>BC106757-1|AAI06758.1| 446|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 446
Score = 45.6 bits (103), Expect = 2e-04
Identities = 32/96 (33%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Frame = +3
Query: 9 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 185
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 186 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKK 287
V+ G+ +RE V++ E RP + FG +
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPR 115
Score = 33.5 bits (73), Expect = 0.76
Identities = 20/71 (28%), Positives = 32/71 (45%), Gaps = 1/71 (1%)
Frame = +3
Query: 441 GEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCSLVMR-LFKLXDMSGGILNFLP 617
G P N + + N++ L G+R++ D R +L L L + +LN +P
Sbjct: 118 GRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVP 177
Query: 618 FLXHFVPRLIG 650
L H +P L G
Sbjct: 178 VLLH-IPALAG 187
>BC066877-1|AAH66877.1| 446|Homo sapiens CYP2D6 protein protein.
Length = 446
Score = 45.6 bits (103), Expect = 2e-04
Identities = 32/96 (33%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Frame = +3
Query: 9 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 185
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 186 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKK 287
V+ G+ +RE V++ E RP + FG +
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPR 115
Score = 33.5 bits (73), Expect = 0.76
Identities = 20/71 (28%), Positives = 32/71 (45%), Gaps = 1/71 (1%)
Frame = +3
Query: 441 GEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCSLVMR-LFKLXDMSGGILNFLP 617
G P N + + N++ L G+R++ D R +L L L + +LN +P
Sbjct: 118 GRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVP 177
Query: 618 FLXHFVPRLIG 650
L H +P L G
Sbjct: 178 VLLH-IPALAG 187
>AY513607-1|AAR90938.1| 100|Homo sapiens truncated cytochrome P450
2A13 variant 4 protein.
Length = 100
Score = 45.2 bits (102), Expect = 2e-04
Identities = 29/80 (36%), Positives = 41/80 (51%), Gaps = 2/80 (2%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 188
R+ RG PPGPTPLP +GN L + E + S++YG + + LG VVV
Sbjct: 27 RKSRGKL-PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVV 80
Query: 189 VTGIELIRE--VSNREVFEG 242
+ G + ++E V E F G
Sbjct: 81 LCGHDAVKEALVDQAEEFSG 100
>J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3
protein.
Length = 502
Score = 44.8 bits (101), Expect = 3e-04
Identities = 42/153 (27%), Positives = 69/153 (45%), Gaps = 8/153 (5%)
Frame = +3
Query: 36 PGPTPLPIVGNLLSVLWESRKF--KCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELI 209
PGPTPLP++GN+LS KF +C+ +KYG + G G + V+ +T ++I
Sbjct: 39 PGPTPLPLLGNVLSYRQGLWKFDTECY--------KKYGKMWGTYEGQLPVLAITDPDVI 90
Query: 210 REVSNREVFEGRPDGFFYTMRSFG----KKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSR 377
R V +E + F RS G K + ++ W R R + +
Sbjct: 91 RTVLVKECY-----SVFTNRRSLGPVGFMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEM 145
Query: 378 FMNVYIGEECEALVQ--LRLADAGEPILVNQMF 470
F I + + LV+ R A+ G+P+ + +F
Sbjct: 146 F--PIIAQYGDVLVRNLRREAEKGKPVTLKDIF 176
>DQ680079-1|ABG25922.1| 347|Homo sapiens truncated cytochrome P450,
family 3, subfamily A, polypeptide 5 protein.
Length = 347
Score = 44.8 bits (101), Expect = 3e-04
Identities = 42/153 (27%), Positives = 69/153 (45%), Gaps = 8/153 (5%)
Frame = +3
Query: 36 PGPTPLPIVGNLLSVLWESRKF--KCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELI 209
PGPTPLP++GN+LS KF +C+ +KYG + G G + V+ +T ++I
Sbjct: 39 PGPTPLPLLGNVLSYRQGLWKFDTECY--------KKYGKMWGTYEGQLPVLAITDPDVI 90
Query: 210 REVSNREVFEGRPDGFFYTMRSFG----KKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSR 377
R V +E + F RS G K + ++ W R R + +
Sbjct: 91 RTVLVKECY-----SVFTNRRSLGPVGFMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEM 145
Query: 378 FMNVYIGEECEALVQ--LRLADAGEPILVNQMF 470
F I + + LV+ R A+ G+P+ + +F
Sbjct: 146 F--PIIAQYGDVLVRNLRREAEKGKPVTLKDIF 176
>BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 protein.
Length = 502
Score = 44.8 bits (101), Expect = 3e-04
Identities = 42/153 (27%), Positives = 69/153 (45%), Gaps = 8/153 (5%)
Frame = +3
Query: 36 PGPTPLPIVGNLLSVLWESRKF--KCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELI 209
PGPTPLP++GN+LS KF +C+ +KYG + G G + V+ +T ++I
Sbjct: 39 PGPTPLPLLGNVLSYRQGLWKFDTECY--------KKYGKMWGTYEGQLPVLAITDPDVI 90
Query: 210 REVSNREVFEGRPDGFFYTMRSFG----KKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSR 377
R V +E + F RS G K + ++ W R R + +
Sbjct: 91 RTVLVKECY-----SVFTNRRSLGPVGFMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEM 145
Query: 378 FMNVYIGEECEALVQ--LRLADAGEPILVNQMF 470
F I + + LV+ R A+ G+P+ + +F
Sbjct: 146 F--PIIAQYGDVLVRNLRREAEKGKPVTLKDIF 176
>AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein.
Length = 502
Score = 44.8 bits (101), Expect = 3e-04
Identities = 42/153 (27%), Positives = 69/153 (45%), Gaps = 8/153 (5%)
Frame = +3
Query: 36 PGPTPLPIVGNLLSVLWESRKF--KCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELI 209
PGPTPLP++GN+LS KF +C+ +KYG + G G + V+ +T ++I
Sbjct: 39 PGPTPLPLLGNVLSYRQGLWKFDTECY--------KKYGKMWGTYEGQLPVLAITDPDVI 90
Query: 210 REVSNREVFEGRPDGFFYTMRSFG----KKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSR 377
R V +E + F RS G K + ++ W R R + +
Sbjct: 91 RTVLVKECY-----SVFTNRRSLGPVGFMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEM 145
Query: 378 FMNVYIGEECEALVQ--LRLADAGEPILVNQMF 470
F I + + LV+ R A+ G+P+ + +F
Sbjct: 146 F--PIIAQYGDVLVRNLRREAEKGKPVTLKDIF 176
>AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 variant protein.
Length = 502
Score = 44.4 bits (100), Expect = 4e-04
Identities = 42/153 (27%), Positives = 69/153 (45%), Gaps = 8/153 (5%)
Frame = +3
Query: 36 PGPTPLPIVGNLLSVLWESRKF--KCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELI 209
PGPTPLP++GN+LS KF +C+ +KYG + G G + V+ +T ++I
Sbjct: 39 PGPTPLPLLGNVLSYRQGLWKFDTECY--------KKYGKMWGTYEGQLPVLAITDPDVI 90
Query: 210 REVSNREVFEGRPDGFFYTMRSFG----KKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSR 377
R V +E + F RS G K + ++ W R R + +
Sbjct: 91 RTVLVKECY-----SVFTNRRSLGPVGFMKSAISLAEDEEWKRIRPLLSPTFTSGKLKEM 145
Query: 378 FMNVYIGEECEALVQ--LRLADAGEPILVNQMF 470
F I + + LV+ R A+ G+P+ + +F
Sbjct: 146 F--PIIAQYGDVLVRNLRREAEKGKPVTLKDIF 176
>DQ211355-2|ABB01373.1| 117|Homo sapiens cytochrome P450 2D6
protein.
Length = 117
Score = 42.3 bits (95), Expect = 0.002
Identities = 31/96 (32%), Positives = 50/96 (52%), Gaps = 3/96 (3%)
Frame = +3
Query: 9 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 185
RR R Y PGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYSPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 186 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKK 287
V+ G+ +RE V++ E RP + FG +
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPR 115
>J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipine
oxidase protein.
Length = 502
Score = 41.9 bits (94), Expect = 0.002
Identities = 48/203 (23%), Positives = 84/203 (41%), Gaps = 7/203 (3%)
Frame = +3
Query: 36 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 215
PGPTPLP +GN+LS K C + +KYG + G G V+ +T ++I+
Sbjct: 39 PGPTPLPFLGNILSY----HKGFC--MFDMECHKKYGKVCGFYDGQQPVLAITDPDMIKT 92
Query: 216 VSNREVFEGRPDGFFYTMRSFG----KKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFM 383
V +E + F R FG K + ++ W R R +L G +
Sbjct: 93 VLVKECY-----SVFTNRRPFGPVGFMKSAISIAEDEEWKRLRS-LLSPTFTSGKLKEMV 146
Query: 384 NVYIGEECEALVQ--LRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCS 557
+ I + + LV+ R A+ G+P+ + +F ++++ G D +
Sbjct: 147 PI-IAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVE 205
Query: 558 LVMRLFKLXDMSGGILNFL-PFL 623
+L + + L+ + PFL
Sbjct: 206 NTKKLLRFDFLDPFFLSIIFPFL 228
>DQ372705-1|ABD16216.1| 150|Homo sapiens mutant cytochrome p450
protein.
Length = 150
Score = 41.5 bits (93), Expect = 0.003
Identities = 26/82 (31%), Positives = 41/82 (50%), Gaps = 2/82 (2%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 188
RR + PPGP P++GN +V + HL + +++YG++ +RLGS +VV
Sbjct: 43 RRRQLRSAPPGPFAWPLIGNAAAV------GQAAHLSFARLARRYGDVFQIRLGSCPIVV 96
Query: 189 VTGIELIRE--VSNREVFEGRP 248
+ G I + V F RP
Sbjct: 97 LNGERAIHQALVQQGSAFADRP 118
>AF280107-4|AAG32288.1| 106|Homo sapiens cytochrome P450
polypeptide 5 protein.
Length = 106
Score = 41.5 bits (93), Expect = 0.003
Identities = 25/69 (36%), Positives = 39/69 (56%), Gaps = 2/69 (2%)
Frame = +3
Query: 36 PGPTPLPIVGNLLSVLWESRKF--KCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELI 209
PGPTPLP++GN+LS KF +C+ +KYG + G G + V+ +T ++I
Sbjct: 39 PGPTPLPLLGNVLSYRQGLWKFDTECY--------KKYGKMWGTYEGQLPVLAITDPDVI 90
Query: 210 REVSNREVF 236
R V +E +
Sbjct: 91 RTVLVKECY 99
>X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (cyp3 locus). ).
Length = 503
Score = 41.1 bits (92), Expect = 0.004
Identities = 43/169 (25%), Positives = 73/169 (43%), Gaps = 6/169 (3%)
Frame = +3
Query: 36 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 215
PGPTPLP +GN+LS K C + +KYG + G G V+ +T ++I+
Sbjct: 39 PGPTPLPFLGNILSY----HKGFC--MFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKT 92
Query: 216 VSNREVFEGRPDGFFYTMRSFG----KKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFM 383
V +E + F R FG K + ++ W R R +L G +
Sbjct: 93 VLVKECY-----SVFTNRRPFGPVGFMKSAISIAEDEEWKRLRS-LLSPTFTSGKLKEMV 146
Query: 384 NVYIGEECEALVQ--LRLADAGEPILVNQMFHITIVNILWRLVAGKRYD 524
+ I + + LV+ R A+ G+P+ + +F ++++ G D
Sbjct: 147 PI-IAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNID 194
>M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA
encoding nifedipine oxidase, complete cds. ).
Length = 503
Score = 41.1 bits (92), Expect = 0.004
Identities = 43/169 (25%), Positives = 73/169 (43%), Gaps = 6/169 (3%)
Frame = +3
Query: 36 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 215
PGPTPLP +GN+LS K C + +KYG + G G V+ +T ++I+
Sbjct: 39 PGPTPLPFLGNILSY----HKGFC--MFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKT 92
Query: 216 VSNREVFEGRPDGFFYTMRSFG----KKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFM 383
V +E + F R FG K + ++ W R R +L G +
Sbjct: 93 VLVKECY-----SVFTNRRPFGPVGFMKSAISIAEDEEWKRLRS-LLSPTFTSGKLKEMV 146
Query: 384 NVYIGEECEALVQ--LRLADAGEPILVNQMFHITIVNILWRLVAGKRYD 524
+ I + + LV+ R A+ G+P+ + +F ++++ G D
Sbjct: 147 PI-IAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNID 194
>M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrome
P-450 nifedipine oxidase mRNA, complet cds. ).
Length = 503
Score = 41.1 bits (92), Expect = 0.004
Identities = 43/169 (25%), Positives = 73/169 (43%), Gaps = 6/169 (3%)
Frame = +3
Query: 36 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 215
PGPTPLP +GN+LS K C + +KYG + G G V+ +T ++I+
Sbjct: 39 PGPTPLPFLGNILSY----HKGFC--MFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKT 92
Query: 216 VSNREVFEGRPDGFFYTMRSFG----KKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFM 383
V +E + F R FG K + ++ W R R +L G +
Sbjct: 93 VLVKECY-----SVFTNRRPFGPVGFMKSAISIAEDEEWKRLRS-LLSPTFTSGKLKEMV 146
Query: 384 NVYIGEECEALVQ--LRLADAGEPILVNQMFHITIVNILWRLVAGKRYD 524
+ I + + LV+ R A+ G+P+ + +F ++++ G D
Sbjct: 147 PI-IAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNID 194
>DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family 3
subfamily A polypeptide 4 protein.
Length = 503
Score = 41.1 bits (92), Expect = 0.004
Identities = 43/169 (25%), Positives = 73/169 (43%), Gaps = 6/169 (3%)
Frame = +3
Query: 36 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 215
PGPTPLP +GN+LS K C + +KYG + G G V+ +T ++I+
Sbjct: 39 PGPTPLPFLGNILSY----HKGFC--MFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKT 92
Query: 216 VSNREVFEGRPDGFFYTMRSFG----KKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFM 383
V +E + F R FG K + ++ W R R +L G +
Sbjct: 93 VLVKECY-----SVFTNRRPFGPVGFMKSAISIAEDEEWKRLRS-LLSPTFTSGKLKEMV 146
Query: 384 NVYIGEECEALVQ--LRLADAGEPILVNQMFHITIVNILWRLVAGKRYD 524
+ I + + LV+ R A+ G+P+ + +F ++++ G D
Sbjct: 147 PI-IAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNID 194
>DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 41.1 bits (92), Expect = 0.004
Identities = 43/169 (25%), Positives = 73/169 (43%), Gaps = 6/169 (3%)
Frame = +3
Query: 36 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 215
PGPTPLP +GN+LS K C + +KYG + G G V+ +T ++I+
Sbjct: 39 PGPTPLPFLGNILSY----HKGFC--MFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKT 92
Query: 216 VSNREVFEGRPDGFFYTMRSFG----KKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFM 383
V +E + F R FG K + ++ W R R +L G +
Sbjct: 93 VLVKECY-----SVFTNRRPFGPVGFMKSAISIAEDEEWKRLRS-LLSPTFTSGKLKEMV 146
Query: 384 NVYIGEECEALVQ--LRLADAGEPILVNQMFHITIVNILWRLVAGKRYD 524
+ I + + LV+ R A+ G+P+ + +F ++++ G D
Sbjct: 147 PI-IAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNID 194
>BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfamily
IIIA, polypeptide 4 protein.
Length = 503
Score = 41.1 bits (92), Expect = 0.004
Identities = 43/169 (25%), Positives = 73/169 (43%), Gaps = 6/169 (3%)
Frame = +3
Query: 36 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 215
PGPTPLP +GN+LS K C + +KYG + G G V+ +T ++I+
Sbjct: 39 PGPTPLPFLGNILSY----HKGFC--MFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKT 92
Query: 216 VSNREVFEGRPDGFFYTMRSFG----KKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFM 383
V +E + F R FG K + ++ W R R +L G +
Sbjct: 93 VLVKECY-----SVFTNRRPFGPVGFMKSAISIAEDEEWKRLRS-LLSPTFTSGKLKEMV 146
Query: 384 NVYIGEECEALVQ--LRLADAGEPILVNQMFHITIVNILWRLVAGKRYD 524
+ I + + LV+ R A+ G+P+ + +F ++++ G D
Sbjct: 147 PI-IAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNID 194
>BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 41.1 bits (92), Expect = 0.004
Identities = 43/169 (25%), Positives = 73/169 (43%), Gaps = 6/169 (3%)
Frame = +3
Query: 36 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 215
PGPTPLP +GN+LS K C + +KYG + G G V+ +T ++I+
Sbjct: 39 PGPTPLPFLGNILSY----HKGFC--MFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKT 92
Query: 216 VSNREVFEGRPDGFFYTMRSFG----KKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFM 383
V +E + F R FG K + ++ W R R +L G +
Sbjct: 93 VLVKECY-----SVFTNRRPFGPVGFMKSAISIAEDEEWKRLRS-LLSPTFTSGKLKEMV 146
Query: 384 NVYIGEECEALVQ--LRLADAGEPILVNQMFHITIVNILWRLVAGKRYD 524
+ I + + LV+ R A+ G+P+ + +F ++++ G D
Sbjct: 147 PI-IAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNID 194
>AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein.
Length = 503
Score = 41.1 bits (92), Expect = 0.004
Identities = 43/169 (25%), Positives = 73/169 (43%), Gaps = 6/169 (3%)
Frame = +3
Query: 36 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 215
PGPTPLP +GN+LS K C + +KYG + G G V+ +T ++I+
Sbjct: 39 PGPTPLPFLGNILSY----HKGFC--MFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKT 92
Query: 216 VSNREVFEGRPDGFFYTMRSFG----KKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFM 383
V +E + F R FG K + ++ W R R +L G +
Sbjct: 93 VLVKECY-----SVFTNRRPFGPVGFMKSAISIAEDEEWKRLRS-LLSPTFTSGKLKEMV 146
Query: 384 NVYIGEECEALVQ--LRLADAGEPILVNQMFHITIVNILWRLVAGKRYD 524
+ I + + LV+ R A+ G+P+ + +F ++++ G D
Sbjct: 147 PI-IAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNID 194
>AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450
polypeptide 4 protein.
Length = 503
Score = 41.1 bits (92), Expect = 0.004
Identities = 43/169 (25%), Positives = 73/169 (43%), Gaps = 6/169 (3%)
Frame = +3
Query: 36 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 215
PGPTPLP +GN+LS K C + +KYG + G G V+ +T ++I+
Sbjct: 39 PGPTPLPFLGNILSY----HKGFC--MFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKT 92
Query: 216 VSNREVFEGRPDGFFYTMRSFG----KKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFM 383
V +E + F R FG K + ++ W R R +L G +
Sbjct: 93 VLVKECY-----SVFTNRRPFGPVGFMKSAISIAEDEEWKRLRS-LLSPTFTSGKLKEMV 146
Query: 384 NVYIGEECEALVQ--LRLADAGEPILVNQMFHITIVNILWRLVAGKRYD 524
+ I + + LV+ R A+ G+P+ + +F ++++ G D
Sbjct: 147 PI-IAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNID 194
>AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4
protein.
Length = 503
Score = 41.1 bits (92), Expect = 0.004
Identities = 43/169 (25%), Positives = 73/169 (43%), Gaps = 6/169 (3%)
Frame = +3
Query: 36 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 215
PGPTPLP +GN+LS K C + +KYG + G G V+ +T ++I+
Sbjct: 39 PGPTPLPFLGNILSY----HKGFC--MFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKT 92
Query: 216 VSNREVFEGRPDGFFYTMRSFG----KKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFM 383
V +E + F R FG K + ++ W R R +L G +
Sbjct: 93 VLVKECY-----SVFTNRRPFGPVGFMKSAISIAEDEEWKRLRS-LLSPTFTSGKLKEMV 146
Query: 384 NVYIGEECEALVQ--LRLADAGEPILVNQMFHITIVNILWRLVAGKRYD 524
+ I + + LV+ R A+ G+P+ + +F ++++ G D
Sbjct: 147 PI-IAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNID 194
>AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4
protein.
Length = 503
Score = 41.1 bits (92), Expect = 0.004
Identities = 43/169 (25%), Positives = 73/169 (43%), Gaps = 6/169 (3%)
Frame = +3
Query: 36 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 215
PGPTPLP +GN+LS K C + +KYG + G G V+ +T ++I+
Sbjct: 39 PGPTPLPFLGNILSY----HKGFC--MFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKT 92
Query: 216 VSNREVFEGRPDGFFYTMRSFG----KKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFM 383
V +E + F R FG K + ++ W R R +L G +
Sbjct: 93 VLVKECY-----SVFTNRRPFGPVGFMKSAISIAEDEEWKRLRS-LLSPTFTSGKLKEMV 146
Query: 384 NVYIGEECEALVQ--LRLADAGEPILVNQMFHITIVNILWRLVAGKRYD 524
+ I + + LV+ R A+ G+P+ + +F ++++ G D
Sbjct: 147 PI-IAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNID 194
>AF171066-1|AAG43404.1| 112|Homo sapiens CYP1B1 variant protein.
Length = 112
Score = 39.1 bits (87), Expect = 0.015
Identities = 23/69 (33%), Positives = 37/69 (53%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 188
RR G PPGP P++GN +V + HL + +++YG++ +RLGS +VV
Sbjct: 44 RRQLGSA-PPGPFAWPLIGNAAAV------GQAAHLSFARLARRYGDVFQIRLGSCPIVV 96
Query: 189 VTGIELIRE 215
+ G I +
Sbjct: 97 LNGERAIHQ 105
>BC012027-1|AAH12027.1| 168|Homo sapiens CYP2U1 protein protein.
Length = 168
Score = 37.9 bits (84), Expect = 0.035
Identities = 31/100 (31%), Positives = 44/100 (44%), Gaps = 20/100 (20%)
Frame = +3
Query: 9 RRHRGLCYPPGPTPLPIVGNLLSVL---------WESRKFKC---------HHLIWQSWS 134
RR R PPGPTP P+VGN VL W S + + ++ +
Sbjct: 52 RRRRARGIPPGPTPWPLVGNFGHVLLPPFLRRRSWLSSRTRAAGIDPSVIGPQVLLAHLA 111
Query: 135 QKYGNLLGLRLGSINVVVVTGIELIRE--VSNREVFEGRP 248
+ YG++ +G VVV++ +RE V EVF RP
Sbjct: 112 RVYGSIFSFFIGHYLVVVLSDFHSVREALVQQAEVFSDRP 151
>AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43.1
protein.
Length = 503
Score = 37.5 bits (83), Expect = 0.047
Identities = 28/99 (28%), Positives = 45/99 (45%)
Frame = +3
Query: 36 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 215
PGPTPLP +G +L L F + ++KYG + GL G ++V+ ++I+
Sbjct: 39 PGPTPLPFLGTILFYLRGLWNFD------RECNEKYGEMWGLYEGQQPMLVIMDPDMIKT 92
Query: 216 VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTR 332
V +E + + F K L F++ W R R
Sbjct: 93 VLVKECYSVFTNQMPLGPMGF-LKSALSFAEDEEWKRIR 130
>AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43.3
protein.
Length = 503
Score = 37.5 bits (83), Expect = 0.047
Identities = 28/99 (28%), Positives = 45/99 (45%)
Frame = +3
Query: 36 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 215
PGPTPLP +G +L L F + ++KYG + GL G ++V+ ++I+
Sbjct: 39 PGPTPLPFLGTILFYLRGLWNFD------RECNEKYGEMWGLYEGQQPMLVIMDPDMIKT 92
Query: 216 VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTR 332
V +E + + F K L F++ W R R
Sbjct: 93 VLVKECYSVFTNQMPLGPMGF-LKSALSFAEDEEWKRIR 130
>AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 37.5 bits (83), Expect = 0.047
Identities = 28/99 (28%), Positives = 45/99 (45%)
Frame = +3
Query: 36 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 215
PGPTPLP +G +L L F + ++KYG + GL G ++V+ ++I+
Sbjct: 39 PGPTPLPFLGTILFYLRGLWNFD------RECNEKYGEMWGLYEGQQPMLVIMDPDMIKT 92
Query: 216 VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTR 332
V +E + + F K L F++ W R R
Sbjct: 93 VLVKECYSVFTNQMPLGPMGF-LKSALSFAEDEEWKRIR 130
>AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43
protein.
Length = 503
Score = 37.5 bits (83), Expect = 0.047
Identities = 28/99 (28%), Positives = 45/99 (45%)
Frame = +3
Query: 36 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 215
PGPTPLP +G +L L F + ++KYG + GL G ++V+ ++I+
Sbjct: 39 PGPTPLPFLGTILFYLRGLWNFD------RECNEKYGEMWGLYEGQQPMLVIMDPDMIKT 92
Query: 216 VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTR 332
V +E + + F K L F++ W R R
Sbjct: 93 VLVKECYSVFTNQMPLGPMGF-LKSALSFAEDEEWKRIR 130
>AF280111-1|AAG33012.1| 250|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 250
Score = 37.5 bits (83), Expect = 0.047
Identities = 28/99 (28%), Positives = 45/99 (45%)
Frame = +3
Query: 36 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 215
PGPTPLP +G +L L F + ++KYG + GL G ++V+ ++I+
Sbjct: 39 PGPTPLPFLGTILFYLRGLWNFD------RECNEKYGEMWGLYEGQQPMLVIMDPDMIKT 92
Query: 216 VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTR 332
V +E + + F K L F++ W R R
Sbjct: 93 VLVKECYSVFTNQMPLGPMGF-LKSALSFAEDEEWKRIR 130
>AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 420
Score = 37.5 bits (83), Expect = 0.047
Identities = 28/99 (28%), Positives = 45/99 (45%)
Frame = +3
Query: 36 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 215
PGPTPLP +G +L L F + ++KYG + GL G ++V+ ++I+
Sbjct: 39 PGPTPLPFLGTILFYLRGLWNFD------RECNEKYGEMWGLYEGQQPMLVIMDPDMIKT 92
Query: 216 VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTR 332
V +E + + F K L F++ W R R
Sbjct: 93 VLVKECYSVFTNQMPLGPMGF-LKSALSFAEDEEWKRIR 130
>AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 504
Score = 37.5 bits (83), Expect = 0.047
Identities = 28/99 (28%), Positives = 45/99 (45%)
Frame = +3
Query: 36 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 215
PGPTPLP +G +L L F + ++KYG + GL G ++V+ ++I+
Sbjct: 39 PGPTPLPFLGTILFYLRGLWNFD------RECNEKYGEMWGLYEGQQPMLVIMDPDMIKT 92
Query: 216 VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTR 332
V +E + + F K L F++ W R R
Sbjct: 93 VLVKECYSVFTNQMPLGPMGF-LKSALSFAEDEEWKRIR 130
>AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 37.5 bits (83), Expect = 0.047
Identities = 28/99 (28%), Positives = 45/99 (45%)
Frame = +3
Query: 36 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 215
PGPTPLP +G +L L F + ++KYG + GL G ++V+ ++I+
Sbjct: 39 PGPTPLPFLGTILFYLRGLWNFD------RECNEKYGEMWGLYEGQQPMLVIMDPDMIKT 92
Query: 216 VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTR 332
V +E + + F K L F++ W R R
Sbjct: 93 VLVKECYSVFTNQMPLGPMGF-LKSALSFAEDEEWKRIR 130
>AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein.
Length = 504
Score = 37.5 bits (83), Expect = 0.047
Identities = 28/99 (28%), Positives = 45/99 (45%)
Frame = +3
Query: 36 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 215
PGPTPLP +G +L L F + ++KYG + GL G ++V+ ++I+
Sbjct: 39 PGPTPLPFLGTILFYLRGLWNFD------RECNEKYGEMWGLYEGQQPMLVIMDPDMIKT 92
Query: 216 VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTR 332
V +E + + F K L F++ W R R
Sbjct: 93 VLVKECYSVFTNQMPLGPMGF-LKSALSFAEDEEWKRIR 130
>AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein.
Length = 503
Score = 37.5 bits (83), Expect = 0.047
Identities = 28/99 (28%), Positives = 45/99 (45%)
Frame = +3
Query: 36 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 215
PGPTPLP +G +L L F + ++KYG + GL G ++V+ ++I+
Sbjct: 39 PGPTPLPFLGTILFYLRGLWNFD------RECNEKYGEMWGLYEGQQPMLVIMDPDMIKT 92
Query: 216 VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTR 332
V +E + + F K L F++ W R R
Sbjct: 93 VLVKECYSVFTNQMPLGPMGF-LKSALSFAEDEEWKRIR 130
>M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver
glucocorticoid-inducible cytochrome P-450 (HLp) mRNA,
complete cds. ).
Length = 504
Score = 36.7 bits (81), Expect = 0.082
Identities = 23/67 (34%), Positives = 35/67 (52%)
Frame = +3
Query: 36 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 215
PGPTPLP +GN+LS K C + +KYG + G G V+ +T ++I+
Sbjct: 39 PGPTPLPFLGNILSY----HKGFC--MFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKL 92
Query: 216 VSNREVF 236
V +E +
Sbjct: 93 VLVKECY 99
>D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein.
Length = 504
Score = 36.7 bits (81), Expect = 0.082
Identities = 23/67 (34%), Positives = 35/67 (52%)
Frame = +3
Query: 36 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 215
PGPTPLP +GN+LS K C + +KYG + G G V+ +T ++I+
Sbjct: 39 PGPTPLPFLGNILSY----HKGFC--MFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKL 92
Query: 216 VSNREVF 236
V +E +
Sbjct: 93 VLVKECY 99
>BC022539-1|AAH22539.1| 500|Homo sapiens cytochrome P450, family
46, subfamily A, polypeptide 1 protein.
Length = 500
Score = 36.7 bits (81), Expect = 0.082
Identities = 47/204 (23%), Positives = 83/204 (40%), Gaps = 9/204 (4%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHL--IWQSWSQKYGNLLGLRLGSINVVVVTGIEL 206
P P P ++G+L W+ + L ++ W++KYG ++ + + V+VT E
Sbjct: 34 PGPPRPSFLLGHL-PCFWKKDEVGGRVLQDVFLDWAKKYGPVVRVNVFHKTSVIVTSPES 92
Query: 207 IREVSNREVFEGRPDGFFYTMRSFGKKL---GLVFS-DGPTWHRTRRFVLKYLKNFGYNS 374
+++ + + FG++L GLV + WH+ RR + S
Sbjct: 93 VKKFLMSTKYNKDSKMYRALQTVFGERLFGQGLVSECNYERWHKQRRVIDLAFSRSSLVS 152
Query: 375 RFMNVYIGEECEALVQL--RLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKK 548
M + E+ E LV++ AD P+ + M T ++IL + G + K
Sbjct: 153 -LMETF-NEKAEQLVEILEAKADGQTPVSMQDMLTYTAMDILAKAAFGMETSMLLGAQKP 210
Query: 549 LCSLVMRLFKLXDMSGGIL-NFLP 617
L V + + S L FLP
Sbjct: 211 LSQAVKLMLEGITASRNTLAKFLP 234
>AF094480-1|AAD41244.1| 500|Homo sapiens cholesterol 24-hydroxylase
protein.
Length = 500
Score = 36.7 bits (81), Expect = 0.082
Identities = 47/204 (23%), Positives = 83/204 (40%), Gaps = 9/204 (4%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSVLWESRKFKCHHL--IWQSWSQKYGNLLGLRLGSINVVVVTGIEL 206
P P P ++G+L W+ + L ++ W++KYG ++ + + V+VT E
Sbjct: 34 PGPPRPSFLLGHL-PCFWKKDEVGGRVLQDVFLDWAKKYGPVVRVNVFHKTSVIVTSPES 92
Query: 207 IREVSNREVFEGRPDGFFYTMRSFGKKL---GLVFS-DGPTWHRTRRFVLKYLKNFGYNS 374
+++ + + FG++L GLV + WH+ RR + S
Sbjct: 93 VKKFLMSTKYNKDSKMYRALQTVFGERLFGQGLVSECNYERWHKQRRVIDLAFSRSSLVS 152
Query: 375 RFMNVYIGEECEALVQL--RLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKK 548
M + E+ E LV++ AD P+ + M T ++IL + G + K
Sbjct: 153 -LMETF-NEKAEQLVEILEAKADGQTPVSMQDMLTYTAMDILAKAAFGMETSMLLGAQKP 210
Query: 549 LCSLVMRLFKLXDMSGGIL-NFLP 617
L V + + S L FLP
Sbjct: 211 LSQAVKLMLEGITASRNTLAKFLP 234
>X54807-1|CAA38578.1| 56|Homo sapiens unspecific monooxygenase
protein.
Length = 56
Score = 35.5 bits (78), Expect = 0.19
Identities = 12/16 (75%), Positives = 15/16 (93%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSV 80
PPGPTPLPI+GN+L +
Sbjct: 30 PPGPTPLPIIGNMLQI 45
>M61858-1|AAA52145.1| 370|Homo sapiens CYP2C17 protein.
Length = 370
Score = 35.5 bits (78), Expect = 0.19
Identities = 24/75 (32%), Positives = 36/75 (48%), Gaps = 1/75 (1%)
Frame = +3
Query: 330 RRFVLKYLKNFGYNSRFMNVYIGEECEALV-QLRLADAGEPILVNQMFHITIVNILWRLV 506
RRF L L+NFG R + + EE LV +LR +A P + N++ ++
Sbjct: 4 RRFCLITLRNFGMGKRSIEDRVQEEARCLVEELRKTNA-SPCDPTFILGCAPCNVICSII 62
Query: 507 AGKRYDLXDQRLKKL 551
KR+D DQ+ L
Sbjct: 63 FHKRFDYKDQQFLNL 77
>AF280107-1|AAG32291.1| 106|Homo sapiens cytochrome P450
polypeptide 43 protein.
Length = 106
Score = 35.5 bits (78), Expect = 0.19
Identities = 21/67 (31%), Positives = 35/67 (52%)
Frame = +3
Query: 36 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 215
PGPTPLP +G +L L F + ++KYG + GL G ++V+ ++I+
Sbjct: 39 PGPTPLPFLGTILFYLRGLWNFD------RECNEKYGEMWGLYEGQQPMLVIMDPDMIKT 92
Query: 216 VSNREVF 236
V +E +
Sbjct: 93 VLVKECY 99
>BX538127-1|CAD98029.1| 310|Homo sapiens hypothetical protein
protein.
Length = 310
Score = 34.3 bits (75), Expect = 0.44
Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
Frame = +3
Query: 330 RRFVLKYLKNFGYNSRFMNVYIGEECEALV-QLRLADAGEPILVNQMFHITIVNILWRLV 506
RRF L L+NFG R + + EE LV +LR +A P + N++ ++
Sbjct: 3 RRFCLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTNA-SPCDPAFILGCAPCNVICSVI 61
Query: 507 AGKRYDLXDQRLKKL 551
R+D DQR L
Sbjct: 62 FHDRFDYKDQRFLNL 76
>AL512656-1|CAI15290.1| 488|Homo sapiens annexin A7 protein.
Length = 488
Score = 34.3 bits (75), Expect = 0.44
Identities = 18/53 (33%), Positives = 26/53 (49%)
Frame = -2
Query: 313 GPSEKTNPSFFPNDLMV*KNPSGLPSNTSRFETSLMSSIPVTTTTLMDPSLKP 155
GP++ P FP M + P G P+ S+ T SS PV + +D S +P
Sbjct: 116 GPAQVPLPGGFPGGQMPSQYPGGQPTYPSQINTDSFSSYPVFSPVSLDYSSEP 168
>AL353731-3|CAI52484.1| 488|Homo sapiens annexin A7 protein.
Length = 488
Score = 34.3 bits (75), Expect = 0.44
Identities = 18/53 (33%), Positives = 26/53 (49%)
Frame = -2
Query: 313 GPSEKTNPSFFPNDLMV*KNPSGLPSNTSRFETSLMSSIPVTTTTLMDPSLKP 155
GP++ P FP M + P G P+ S+ T SS PV + +D S +P
Sbjct: 116 GPAQVPLPGGFPGGQMPSQYPGGQPTYPSQINTDSFSSYPVFSPVSLDYSSEP 168
>X58906-1|CAA41709.1| 495|Homo sapiens steroid 21-monooxygenase
protein.
Length = 495
Score = 31.9 bits (69), Expect = 2.3
Identities = 37/170 (21%), Positives = 65/170 (38%), Gaps = 3/170 (1%)
Frame = +3
Query: 132 SQKYGNLLGLRLGSINVVVVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 305
+QK+G + L LG +VVV+ I E V F GRP+ Y + S L
Sbjct: 53 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYP-DLSLG 111
Query: 306 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIV 485
D + + + + G M + + + + A G P+ + + F +
Sbjct: 112 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 170
Query: 486 NILWRLVAGKRYDLXDQRLKKLCSLVMRLFKL-XDMSGGILNFLPFLXHF 632
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 171 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 219
>X58904-1|CAA41707.1| 371|Homo sapiens steroid 21-monooxygenase
protein.
Length = 371
Score = 31.9 bits (69), Expect = 2.3
Identities = 37/170 (21%), Positives = 65/170 (38%), Gaps = 3/170 (1%)
Frame = +3
Query: 132 SQKYGNLLGLRLGSINVVVVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 305
+QK+G + L LG +VVV+ I E V F GRP+ Y + S L
Sbjct: 52 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYP-DLSLG 110
Query: 306 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIV 485
D + + + + G M + + + + A G P+ + + F +
Sbjct: 111 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 169
Query: 486 NILWRLVAGKRYDLXDQRLKKLCSLVMRLFKL-XDMSGGILNFLPFLXHF 632
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 170 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 218
>X58902-1|CAA41706.1| 372|Homo sapiens steroid 21-monooxygenase
protein.
Length = 372
Score = 31.9 bits (69), Expect = 2.3
Identities = 37/170 (21%), Positives = 65/170 (38%), Gaps = 3/170 (1%)
Frame = +3
Query: 132 SQKYGNLLGLRLGSINVVVVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 305
+QK+G + L LG +VVV+ I E V F GRP+ Y + S L
Sbjct: 53 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYP-DLSLG 111
Query: 306 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIV 485
D + + + + G M + + + + A G P+ + + F +
Sbjct: 112 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 170
Query: 486 NILWRLVAGKRYDLXDQRLKKLCSLVMRLFKL-XDMSGGILNFLPFLXHF 632
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 171 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 219
>X58900-1|CAA41704.1| 372|Homo sapiens steroid 21-monooxygenase
protein.
Length = 372
Score = 31.9 bits (69), Expect = 2.3
Identities = 37/170 (21%), Positives = 65/170 (38%), Gaps = 3/170 (1%)
Frame = +3
Query: 132 SQKYGNLLGLRLGSINVVVVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 305
+QK+G + L LG +VVV+ I E V F GRP+ Y + S L
Sbjct: 53 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYP-DLSLG 111
Query: 306 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIV 485
D + + + + G M + + + + A G P+ + + F +
Sbjct: 112 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 170
Query: 486 NILWRLVAGKRYDLXDQRLKKLCSLVMRLFKL-XDMSGGILNFLPFLXHF 632
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 171 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 219
>M28548-1|AAA52065.1| 495|Homo sapiens protein ( Human mutant
21-hydroxylase B gene, complete cds. ).
Length = 495
Score = 31.9 bits (69), Expect = 2.3
Identities = 37/170 (21%), Positives = 65/170 (38%), Gaps = 3/170 (1%)
Frame = +3
Query: 132 SQKYGNLLGLRLGSINVVVVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 305
+QK+G + L LG +VVV+ I E V F GRP+ Y + S L
Sbjct: 53 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYP-DLSLG 111
Query: 306 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIV 485
D + + + + G M + + + + A G P+ + + F +
Sbjct: 112 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 170
Query: 486 NILWRLVAGKRYDLXDQRLKKLCSLVMRLFKL-XDMSGGILNFLPFLXHF 632
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 171 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 219
>M26856-1|AAA52064.1| 495|Homo sapiens protein ( Human
21-hydroxylase B gene, complete cds. ).
Length = 495
Score = 31.9 bits (69), Expect = 2.3
Identities = 37/170 (21%), Positives = 65/170 (38%), Gaps = 3/170 (1%)
Frame = +3
Query: 132 SQKYGNLLGLRLGSINVVVVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 305
+QK+G + L LG +VVV+ I E V F GRP+ Y + S L
Sbjct: 53 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYP-DLSLG 111
Query: 306 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIV 485
D + + + + G M + + + + A G P+ + + F +
Sbjct: 112 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 170
Query: 486 NILWRLVAGKRYDLXDQRLKKLCSLVMRLFKL-XDMSGGILNFLPFLXHF 632
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 171 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 219
>M21550-1|AAA52063.1| 495|Homo sapiens CYP21 protein.
Length = 495
Score = 31.9 bits (69), Expect = 2.3
Identities = 37/170 (21%), Positives = 65/170 (38%), Gaps = 3/170 (1%)
Frame = +3
Query: 132 SQKYGNLLGLRLGSINVVVVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 305
+QK+G + L LG +VVV+ I E V F GRP+ Y + S L
Sbjct: 53 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSKNYP-DLSLG 111
Query: 306 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIV 485
D + + + + G M + + + + A G P+ + + F +
Sbjct: 112 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 170
Query: 486 NILWRLVAGKRYDLXDQRLKKLCSLVMRLFKL-XDMSGGILNFLPFLXHF 632
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 171 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 219
>M13936-1|AAA59695.1| 494|Homo sapiens CYP21P protein.
Length = 494
Score = 31.9 bits (69), Expect = 2.3
Identities = 37/170 (21%), Positives = 65/170 (38%), Gaps = 3/170 (1%)
Frame = +3
Query: 132 SQKYGNLLGLRLGSINVVVVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 305
+QK+G + L LG +VVV+ I E V F GRP+ Y + S L
Sbjct: 52 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSKNYP-DLSLG 110
Query: 306 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIV 485
D + + + + G M + + + + A G P+ + + F +
Sbjct: 111 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 169
Query: 486 NILWRLVAGKRYDLXDQRLKKLCSLVMRLFKL-XDMSGGILNFLPFLXHF 632
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 170 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 218
>M12792-1|AAB59440.1| 494|Homo sapiens steroid 21-hydroxylase
protein.
Length = 494
Score = 31.9 bits (69), Expect = 2.3
Identities = 37/170 (21%), Positives = 65/170 (38%), Gaps = 3/170 (1%)
Frame = +3
Query: 132 SQKYGNLLGLRLGSINVVVVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 305
+QK+G + L LG +VVV+ I E V F GRP+ Y + S L
Sbjct: 52 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSKNYP-DLSLG 110
Query: 306 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIV 485
D + + + + G M + + + + A G P+ + + F +
Sbjct: 111 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 169
Query: 486 NILWRLVAGKRYDLXDQRLKKLCSLVMRLFKL-XDMSGGILNFLPFLXHF 632
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 170 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 218
>D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa
protein.
Length = 503
Score = 31.9 bits (69), Expect = 2.3
Identities = 45/211 (21%), Positives = 83/211 (39%), Gaps = 8/211 (3%)
Frame = +3
Query: 36 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 215
PGPTPLP +GN LS K + +KY + G+ ++ +T ++I+
Sbjct: 39 PGPTPLPFLGNALSFR------KGYWTFDMECYKKYRKVWGIYDCQQPMLAITDPDMIKT 92
Query: 216 VSNREVFEGRPDGFFYTMRSFG----KKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFM 383
V +E + F R FG K + ++ W R R +L G +
Sbjct: 93 VLVKECY-----SVFTNRRPFGPVGFMKNAISIAEDEEWKRIRS-LLSPTFTSGKLKEMV 146
Query: 384 NVYIGEECEALVQ--LRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCS 557
+ I + + LV+ R A+ G+P+ + +F ++++ G D +
Sbjct: 147 PI-IAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVITSTSFGVSIDSLNNPQDPFVE 205
Query: 558 LVMRLFKLXDMSGGILNF--LPFLXHFVPRL 644
+L + + +L+ PFL + L
Sbjct: 206 NTKKLLRFNPLDPFVLSIKVFPFLTPILEAL 236
>BX679671-8|CAM26070.1| 494|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 494
Score = 31.9 bits (69), Expect = 2.3
Identities = 37/170 (21%), Positives = 65/170 (38%), Gaps = 3/170 (1%)
Frame = +3
Query: 132 SQKYGNLLGLRLGSINVVVVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 305
+QK+G + L LG +VVV+ I E V F GRP+ Y + S L
Sbjct: 52 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSKNYP-DLSLG 110
Query: 306 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIV 485
D + + + + G M + + + + A G P+ + + F +
Sbjct: 111 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 169
Query: 486 NILWRLVAGKRYDLXDQRLKKLCSLVMRLFKL-XDMSGGILNFLPFLXHF 632
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 170 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 218
>BC125182-1|AAI25183.1| 494|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 494
Score = 31.9 bits (69), Expect = 2.3
Identities = 37/170 (21%), Positives = 65/170 (38%), Gaps = 3/170 (1%)
Frame = +3
Query: 132 SQKYGNLLGLRLGSINVVVVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 305
+QK+G + L LG +VVV+ I E V F GRP+ Y + S L
Sbjct: 52 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSKNYP-DLSLG 110
Query: 306 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIV 485
D + + + + G M + + + + A G P+ + + F +
Sbjct: 111 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 169
Query: 486 NILWRLVAGKRYDLXDQRLKKLCSLVMRLFKL-XDMSGGILNFLPFLXHF 632
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 170 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 218
>BC125181-1|AAI25182.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 31.9 bits (69), Expect = 2.3
Identities = 37/170 (21%), Positives = 65/170 (38%), Gaps = 3/170 (1%)
Frame = +3
Query: 132 SQKYGNLLGLRLGSINVVVVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 305
+QK+G + L LG +VVV+ I E V F GRP+ Y + S L
Sbjct: 53 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYP-DLSLG 111
Query: 306 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIV 485
D + + + + G M + + + + A G P+ + + F +
Sbjct: 112 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 170
Query: 486 NILWRLVAGKRYDLXDQRLKKLCSLVMRLFKL-XDMSGGILNFLPFLXHF 632
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 171 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 219
>BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 7 protein.
Length = 503
Score = 31.9 bits (69), Expect = 2.3
Identities = 45/211 (21%), Positives = 83/211 (39%), Gaps = 8/211 (3%)
Frame = +3
Query: 36 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 215
PGPTPLP +GN LS K + +KY + G+ ++ +T ++I+
Sbjct: 39 PGPTPLPFLGNALSFR------KGYWTFDMECYKKYRKVWGIYDCQQPMLAITDPDMIKT 92
Query: 216 VSNREVFEGRPDGFFYTMRSFG----KKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFM 383
V +E + F R FG K + ++ W R R +L G +
Sbjct: 93 VLVKECY-----SVFTNRRPFGPVGFMKNAISIAEDEEWKRIRS-LLSPTFTSGKLKEMV 146
Query: 384 NVYIGEECEALVQ--LRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCS 557
+ I + + LV+ R A+ G+P+ + +F ++++ G D +
Sbjct: 147 PI-IAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVITSTSFGVSIDSLNNPQDPFVE 205
Query: 558 LVMRLFKLXDMSGGILNF--LPFLXHFVPRL 644
+L + + +L+ PFL + L
Sbjct: 206 NTKKLLRFNPLDPFVLSIKVFPFLTPILEAL 236
>AM183951-1|CAJ75805.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 31.9 bits (69), Expect = 2.3
Identities = 37/170 (21%), Positives = 65/170 (38%), Gaps = 3/170 (1%)
Frame = +3
Query: 132 SQKYGNLLGLRLGSINVVVVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 305
+QK+G + L LG +VVV+ I E V F GRP+ Y + S L
Sbjct: 52 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYP-DLSLG 110
Query: 306 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIV 485
D + + + + G M + + + + A G P+ + + F +
Sbjct: 111 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 169
Query: 486 NILWRLVAGKRYDLXDQRLKKLCSLVMRLFKL-XDMSGGILNFLPFLXHF 632
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 170 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 218
>AM183950-1|CAJ75804.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 31.9 bits (69), Expect = 2.3
Identities = 37/170 (21%), Positives = 65/170 (38%), Gaps = 3/170 (1%)
Frame = +3
Query: 132 SQKYGNLLGLRLGSINVVVVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 305
+QK+G + L LG +VVV+ I E V F GRP+ Y + S L
Sbjct: 52 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYP-DLSLG 110
Query: 306 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIV 485
D + + + + G M + + + + A G P+ + + F +
Sbjct: 111 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 169
Query: 486 NILWRLVAGKRYDLXDQRLKKLCSLVMRLFKL-XDMSGGILNFLPFLXHF 632
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 170 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 218
>AM183949-1|CAJ75803.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 31.9 bits (69), Expect = 2.3
Identities = 37/170 (21%), Positives = 65/170 (38%), Gaps = 3/170 (1%)
Frame = +3
Query: 132 SQKYGNLLGLRLGSINVVVVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 305
+QK+G + L LG +VVV+ I E V F GRP+ Y + S L
Sbjct: 52 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYP-DLSLG 110
Query: 306 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIV 485
D + + + + G M + + + + A G P+ + + F +
Sbjct: 111 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 169
Query: 486 NILWRLVAGKRYDLXDQRLKKLCSLVMRLFKL-XDMSGGILNFLPFLXHF 632
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 170 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 218
>AM183948-1|CAJ75802.1| 494|Homo sapiens steroid 21-hydroxylase
protein.
Length = 494
Score = 31.9 bits (69), Expect = 2.3
Identities = 37/170 (21%), Positives = 65/170 (38%), Gaps = 3/170 (1%)
Frame = +3
Query: 132 SQKYGNLLGLRLGSINVVVVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 305
+QK+G + L LG +VVV+ I E V F GRP+ Y + S L
Sbjct: 52 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYP-DLSLG 110
Query: 306 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIV 485
D + + + + G M + + + + A G P+ + + F +
Sbjct: 111 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 169
Query: 486 NILWRLVAGKRYDLXDQRLKKLCSLVMRLFKL-XDMSGGILNFLPFLXHF 632
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 170 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 218
>AM183947-1|CAJ75801.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 31.9 bits (69), Expect = 2.3
Identities = 37/170 (21%), Positives = 65/170 (38%), Gaps = 3/170 (1%)
Frame = +3
Query: 132 SQKYGNLLGLRLGSINVVVVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 305
+QK+G + L LG +VVV+ I E V F GRP+ Y + S L
Sbjct: 52 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYP-DLSLG 110
Query: 306 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIV 485
D + + + + G M + + + + A G P+ + + F +
Sbjct: 111 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 169
Query: 486 NILWRLVAGKRYDLXDQRLKKLCSLVMRLFKL-XDMSGGILNFLPFLXHF 632
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 170 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 218
>AM086565-1|CAJ31104.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 31.9 bits (69), Expect = 2.3
Identities = 37/170 (21%), Positives = 65/170 (38%), Gaps = 3/170 (1%)
Frame = +3
Query: 132 SQKYGNLLGLRLGSINVVVVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 305
+QK+G + L LG +VVV+ I E V F GRP+ Y + S L
Sbjct: 52 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYP-DLSLG 110
Query: 306 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIV 485
D + + + + G M + + + + A G P+ + + F +
Sbjct: 111 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 169
Query: 486 NILWRLVAGKRYDLXDQRLKKLCSLVMRLFKL-XDMSGGILNFLPFLXHF 632
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 170 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 218
>AL929593-1|CAI41779.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 31.9 bits (69), Expect = 2.3
Identities = 37/170 (21%), Positives = 65/170 (38%), Gaps = 3/170 (1%)
Frame = +3
Query: 132 SQKYGNLLGLRLGSINVVVVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 305
+QK+G + L LG +VVV+ I E V F GRP+ Y + S L
Sbjct: 53 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYP-DLSLG 111
Query: 306 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIV 485
D + + + + G M + + + + A G P+ + + F +
Sbjct: 112 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 170
Query: 486 NILWRLVAGKRYDLXDQRLKKLCSLVMRLFKL-XDMSGGILNFLPFLXHF 632
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 171 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 219
>AL662849-18|CAI17479.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 31.9 bits (69), Expect = 2.3
Identities = 37/170 (21%), Positives = 65/170 (38%), Gaps = 3/170 (1%)
Frame = +3
Query: 132 SQKYGNLLGLRLGSINVVVVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 305
+QK+G + L LG +VVV+ I E V F GRP+ Y + S L
Sbjct: 53 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYP-DLSLG 111
Query: 306 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIV 485
D + + + + G M + + + + A G P+ + + F +
Sbjct: 112 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 170
Query: 486 NILWRLVAGKRYDLXDQRLKKLCSLVMRLFKL-XDMSGGILNFLPFLXHF 632
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 171 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 219
>AL645922-24|CAI41754.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 31.9 bits (69), Expect = 2.3
Identities = 37/170 (21%), Positives = 65/170 (38%), Gaps = 3/170 (1%)
Frame = +3
Query: 132 SQKYGNLLGLRLGSINVVVVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 305
+QK+G + L LG +VVV+ I E V F GRP+ Y + S L
Sbjct: 53 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYP-DLSLG 111
Query: 306 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIV 485
D + + + + G M + + + + A G P+ + + F +
Sbjct: 112 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 170
Query: 486 NILWRLVAGKRYDLXDQRLKKLCSLVMRLFKL-XDMSGGILNFLPFLXHF 632
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 171 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 219
>AL049547-7|CAB89301.1| 495|Homo sapiens dJ34F7.3 (cytochrome P450,
subfamily XXIA (steroid 21-hydroxylase, congenital a
protein.
Length = 495
Score = 31.9 bits (69), Expect = 2.3
Identities = 37/170 (21%), Positives = 65/170 (38%), Gaps = 3/170 (1%)
Frame = +3
Query: 132 SQKYGNLLGLRLGSINVVVVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 305
+QK+G + L LG +VVV+ I E V F GRP+ Y + S L
Sbjct: 53 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYP-DLSLG 111
Query: 306 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIV 485
D + + + + G M + + + + A G P+ + + F +
Sbjct: 112 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 170
Query: 486 NILWRLVAGKRYDLXDQRLKKLCSLVMRLFKL-XDMSGGILNFLPFLXHF 632
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 171 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 219
>AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant
3A7 protein.
Length = 535
Score = 31.9 bits (69), Expect = 2.3
Identities = 45/211 (21%), Positives = 83/211 (39%), Gaps = 8/211 (3%)
Frame = +3
Query: 36 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 215
PGPTPLP +GN LS K + +KY + G+ ++ +T ++I+
Sbjct: 39 PGPTPLPFLGNALSFR------KGYWTFDMECYKKYRKVWGIYDCQQPMLAITDPDMIKT 92
Query: 216 VSNREVFEGRPDGFFYTMRSFG----KKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFM 383
V +E + F R FG K + ++ W R R +L G +
Sbjct: 93 VLVKECY-----SVFTNRRPFGPVGFMKNAISIAEDEEWKRIRS-LLSPTFTSGKLKEMV 146
Query: 384 NVYIGEECEALVQ--LRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCS 557
+ I + + LV+ R A+ G+P+ + +F ++++ G D +
Sbjct: 147 PI-IAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVITSTSFGVSIDSLNNPQDPFVE 205
Query: 558 LVMRLFKLXDMSGGILNF--LPFLXHFVPRL 644
+L + + +L+ PFL + L
Sbjct: 206 NTKKLLRFNPLDPFVLSIKVFPFLTPILEAL 236
>AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450
polypeptide 7 protein.
Length = 503
Score = 31.9 bits (69), Expect = 2.3
Identities = 45/211 (21%), Positives = 83/211 (39%), Gaps = 8/211 (3%)
Frame = +3
Query: 36 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 215
PGPTPLP +GN LS K + +KY + G+ ++ +T ++I+
Sbjct: 39 PGPTPLPFLGNALSFR------KGYWTFDMECYKKYRKVWGIYDCQQPMLAITDPDMIKT 92
Query: 216 VSNREVFEGRPDGFFYTMRSFG----KKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFM 383
V +E + F R FG K + ++ W R R +L G +
Sbjct: 93 VLVKECY-----SVFTNRRPFGPVGFMKNAISIAEDEEWKRIRS-LLSPTFTSGKLKEMV 146
Query: 384 NVYIGEECEALVQ--LRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCS 557
+ I + + LV+ R A+ G+P+ + +F ++++ G D +
Sbjct: 147 PI-IAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVITSTSFGVSIDSLNNPQDPFVE 205
Query: 558 LVMRLFKLXDMSGGILNF--LPFLXHFVPRL 644
+L + + +L+ PFL + L
Sbjct: 206 NTKKLLRFNPLDPFVLSIKVFPFLTPILEAL 236
>AF019413-2|AAB67982.1| 495|Homo sapiens cytochrome P450
21-hydroxylase protein.
Length = 495
Score = 31.9 bits (69), Expect = 2.3
Identities = 37/170 (21%), Positives = 65/170 (38%), Gaps = 3/170 (1%)
Frame = +3
Query: 132 SQKYGNLLGLRLGSINVVVVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 305
+QK+G + L LG +VVV+ I E V F GRP+ Y + S L
Sbjct: 53 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYP-DLSLG 111
Query: 306 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRLADAGEPILVNQMFHITIV 485
D + + + + G M + + + + A G P+ + + F +
Sbjct: 112 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 170
Query: 486 NILWRLVAGKRYDLXDQRLKKLCSLVMRLFKL-XDMSGGILNFLPFLXHF 632
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 171 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 219
>X56452-1|CAA39833.1| 56|Homo sapiens unspecific monooxygenase
protein.
Length = 56
Score = 31.5 bits (68), Expect = 3.1
Identities = 11/16 (68%), Positives = 14/16 (87%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSV 80
P GPTPLPI+GN+L +
Sbjct: 30 PSGPTPLPIIGNILQL 45
>AF081569-1|AAD25924.1| 52|Homo sapiens cytochrome P450 protein.
Length = 52
Score = 31.5 bits (68), Expect = 3.1
Identities = 11/16 (68%), Positives = 14/16 (87%)
Frame = +3
Query: 33 PPGPTPLPIVGNLLSV 80
PPGP PLP++GNLL +
Sbjct: 31 PPGPRPLPLLGNLLQM 46
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 114,375,968
Number of Sequences: 237096
Number of extensions: 2639062
Number of successful extensions: 6125
Number of sequences better than 10.0: 259
Number of HSP's better than 10.0 without gapping: 5508
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5860
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8287202872
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -