Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P06_F_I19
(727 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_A5A7A0 Cluster: Mevalonate kinase; n=1; Bombyx mori|Rep... 217 2e-55
UniRef50_UPI00015B4200 Cluster: PREDICTED: similar to mevalonate... 71 4e-11
UniRef50_UPI0000587FA1 Cluster: PREDICTED: similar to Mevalonate... 66 1e-09
UniRef50_A7SJK4 Cluster: Predicted protein; n=1; Nematostella ve... 63 6e-09
UniRef50_UPI0000D56452 Cluster: PREDICTED: similar to mevalonate... 63 8e-09
UniRef50_UPI0000E810F5 Cluster: PREDICTED: hypothetical protein;... 57 5e-07
UniRef50_UPI000155619E Cluster: PREDICTED: hypothetical protein,... 55 2e-06
UniRef50_Q65XX9 Cluster: Putative uncharacterized protein; n=5; ... 55 2e-06
UniRef50_A3LQ81 Cluster: Mevalonate kinase; n=5; Saccharomycetal... 55 2e-06
UniRef50_Q03426 Cluster: Mevalonate kinase; n=26; Euteleostomi|R... 54 3e-06
UniRef50_Q6CEF6 Cluster: Yarrowia lipolytica chromosome B of str... 54 5e-06
UniRef50_UPI0000DB6B27 Cluster: PREDICTED: similar to Mevalonate... 52 1e-05
UniRef50_Q7PWI8 Cluster: ENSANGP00000021364; n=2; Culicidae|Rep:... 52 2e-05
UniRef50_Q0UWF5 Cluster: Putative uncharacterized protein; n=1; ... 52 2e-05
UniRef50_Q4WP25 Cluster: Mevalonate kinase; n=15; Pezizomycotina... 50 6e-05
UniRef50_Q86AG7 Cluster: Similar to Rattus norvegicus (Rat). Mev... 49 1e-04
UniRef50_Q4TG59 Cluster: Chromosome undetermined SCAF3891, whole... 49 1e-04
UniRef50_A2SR97 Cluster: Mevalonate kinase; n=4; Methanomicrobia... 48 3e-04
UniRef50_Q09780 Cluster: Putative mevalonate kinase; n=1; Schizo... 47 4e-04
UniRef50_Q8TT37 Cluster: Mevalonate kinase; n=5; Euryarchaeota|R... 46 7e-04
UniRef50_P07277 Cluster: Mevalonate kinase; n=3; Saccharomycetal... 46 0.001
UniRef50_Q50559 Cluster: Mevalonate kinase; n=2; Methanothermoba... 46 0.001
UniRef50_Q0LHN3 Cluster: Mevalonate kinase; n=2; Chloroflexi (cl... 46 0.001
UniRef50_Q7K2V9 Cluster: GH04687p; n=1; Drosophila melanogaster|... 46 0.001
UniRef50_A0B6E3 Cluster: Mevalonate kinase; n=1; Methanosaeta th... 46 0.001
UniRef50_Q9V187 Cluster: Mevalonate kinase; n=4; Thermococcaceae... 46 0.001
UniRef50_Q58487 Cluster: Mevalonate kinase; n=1; Methanocaldococ... 44 0.003
UniRef50_Q756D2 Cluster: AER335Wp; n=3; Saccharomycetaceae|Rep: ... 44 0.004
UniRef50_O27995 Cluster: Mevalonate kinase; n=1; Archaeoglobus f... 44 0.004
UniRef50_UPI000155611C Cluster: PREDICTED: hypothetical protein,... 44 0.005
UniRef50_Q9HQI6 Cluster: Mevalonate kinase; n=5; Halobacteriacea... 43 0.007
UniRef50_Q2HTL9 Cluster: Mevalonate and galactokinase; n=5; core... 43 0.009
UniRef50_A1RYL2 Cluster: Mevalonate kinase; n=1; Thermofilum pen... 43 0.009
UniRef50_P46086 Cluster: Mevalonate kinase; n=8; Magnoliophyta|R... 43 0.009
UniRef50_A5UV63 Cluster: Mevalonate kinase; n=3; Chloroflexaceae... 42 0.016
UniRef50_A2E1U7 Cluster: Mevalonate kinase family protein; n=1; ... 41 0.036
UniRef50_A7DRD8 Cluster: Mevalonate kinase; n=1; Candidatus Nitr... 41 0.036
UniRef50_UPI00015BB033 Cluster: mevalonate kinase; n=1; Ignicocc... 40 0.063
UniRef50_Q2NG06 Cluster: Putative mevalonate kinase; n=1; Methan... 40 0.063
UniRef50_A5UN66 Cluster: Mevalonate kinase; n=1; Methanobrevibac... 40 0.063
UniRef50_A3H636 Cluster: Mevalonate kinase; n=1; Caldivirga maqu... 40 0.063
UniRef50_Q74JA4 Cluster: Mevalonate kinase; n=7; Lactobacillus|R... 40 0.083
UniRef50_Q2BIK0 Cluster: Mevalonate kinase, putative; n=1; Neptu... 40 0.083
UniRef50_Q8TWN9 Cluster: Mevalonate kinase; n=1; Methanopyrus ka... 39 0.11
UniRef50_A2BL67 Cluster: Mevalonate kinase; n=1; Hyperthermus bu... 39 0.14
UniRef50_Q9Y946 Cluster: Mevalonate kinase; n=1; Aeropyrum perni... 39 0.14
UniRef50_Q8L1I1 Cluster: Phosphomevalonate kinase; n=1; Paracocc... 38 0.19
UniRef50_A6G140 Cluster: Hydroxymethylglutaryl-CoA reductase; n=... 38 0.19
UniRef50_Q8L1I2 Cluster: Mevalonate kinase; n=1; Paracoccus zeax... 38 0.33
UniRef50_A5EVP5 Cluster: GHMP kinase family protein; n=1; Dichel... 38 0.33
UniRef50_A5EUV5 Cluster: GHMP kinase family protein; n=1; Dichel... 38 0.33
UniRef50_Q6LXL5 Cluster: Mevalonate kinase; n=5; Methanococcus|R... 38 0.33
UniRef50_Q22LZ8 Cluster: ATPase, AAA family protein; n=1; Tetrah... 37 0.44
UniRef50_A0E671 Cluster: Chromosome undetermined scaffold_8, who... 37 0.44
UniRef50_Q7QVN5 Cluster: GLP_305_18405_19430; n=1; Giardia lambl... 36 0.77
UniRef50_Q38X71 Cluster: Mevalonate kinase; n=1; Lactobacillus s... 36 1.0
UniRef50_Q03FN7 Cluster: Mevalonate kinase; n=1; Pediococcus pen... 36 1.0
UniRef50_A6G138 Cluster: Mevalonate kinase; n=1; Plesiocystis pa... 36 1.0
UniRef50_Q6C026 Cluster: Similarity; n=1; Yarrowia lipolytica|Re... 36 1.0
UniRef50_Q83DT4 Cluster: Phosphomevalonate kinase, putative; n=2... 36 1.3
UniRef50_A6GIJ2 Cluster: Putative uncharacterized protein; n=1; ... 36 1.3
UniRef50_A2U564 Cluster: Mevalonate kinase; n=1; Bacillus coagul... 36 1.3
UniRef50_Q9FD69 Cluster: Mevalonate kinase; n=4; Enterococcus|Re... 35 2.4
UniRef50_Q2BIJ9 Cluster: GHMP kinase; n=1; Neptuniibacter caesar... 35 2.4
UniRef50_Q2GZQ7 Cluster: Putative uncharacterized protein; n=1; ... 35 2.4
UniRef50_Q97UL6 Cluster: (Phospho) mevalonate kinase, putative; ... 35 2.4
UniRef50_A3HYY0 Cluster: Galactokinase; n=1; Algoriphagus sp. PR... 34 3.1
UniRef50_A3DL21 Cluster: Mevalonate kinase; n=1; Staphylothermus... 34 3.1
UniRef50_Q6ALT2 Cluster: Putative uncharacterized protein; n=1; ... 34 4.1
UniRef50_A5VK03 Cluster: Mevalonate kinase; n=2; Lactobacillus r... 34 4.1
UniRef50_A4VT18 Cluster: Mevalonate kinase; n=4; Streptococcus|R... 34 4.1
UniRef50_Q8F618 Cluster: Putative uncharacterized protein; n=2; ... 33 5.4
UniRef50_Q83DT3 Cluster: Mevalonate kinase, putative; n=3; Coxie... 33 5.4
UniRef50_Q8H912 Cluster: Putative zinc knuckle domain containing... 33 5.4
UniRef50_Q60ED2 Cluster: Putative uncharacterized protein OSJNBa... 33 5.4
UniRef50_Q8SQK4 Cluster: MEVALONATE KINASE; n=1; Encephalitozoon... 33 5.4
UniRef50_UPI0000DB7B87 Cluster: PREDICTED: similar to CG5127-PA ... 33 7.2
UniRef50_Q08UJ8 Cluster: Mevalonate kinase; n=2; Cystobacterinea... 33 7.2
UniRef50_Q031R4 Cluster: Mevalonate kinase; n=3; Lactococcus lac... 33 7.2
UniRef50_A4AD88 Cluster: Galactokinase; n=1; Congregibacter lito... 33 7.2
UniRef50_A1VCN1 Cluster: Small multidrug resistance protein; n=4... 33 7.2
UniRef50_Q7XJS3 Cluster: At2g17440 protein; n=3; Brassicaceae|Re... 33 7.2
UniRef50_Q8ZTT2 Cluster: Mevalonate kinase; n=4; Pyrobaculum|Rep... 33 7.2
UniRef50_Q1WU40 Cluster: Mevalonate kinase; n=1; Lactobacillus s... 33 9.5
UniRef50_Q9VR26 Cluster: CG3294-PA, isoform A; n=4; Sophophora|R... 33 9.5
UniRef50_Q8TQ19 Cluster: Putative uncharacterized protein; n=2; ... 33 9.5
>UniRef50_A5A7A0 Cluster: Mevalonate kinase; n=1; Bombyx mori|Rep:
Mevalonate kinase - Bombyx mori (Silk moth)
Length = 413
Score = 217 bits (531), Expect = 2e-55
Identities = 103/105 (98%), Positives = 103/105 (98%)
Frame = +3
Query: 381 GITGKFSWRLPHKIDHDYHLRRVEEYLHLIKPNFDSLPNNQKNSLRSFLYVFSGIFGSTY 560
GITGKFSWRLPHKIDHDYHLRRVEEYLHLIKPNFDSLPNNQKNSLRSFLYVFSGIFGSTY
Sbjct: 87 GITGKFSWRLPHKIDHDYHLRRVEEYLHLIKPNFDSLPNNQKNSLRSFLYVFSGIFGSTY 146
Query: 561 LPVKSMDISMGSELTIGAGTGSSASFAVCLAGALIQLLKLKSLRG 695
LPVKSMDISMGSELTIGAGTGSSASFAVCLAGALIQLLKLKS G
Sbjct: 147 LPVKSMDISMGSELTIGAGTGSSASFAVCLAGALIQLLKLKSSSG 191
Score = 183 bits (445), Expect = 5e-45
Identities = 87/87 (100%), Positives = 87/87 (100%)
Frame = +2
Query: 122 MLTAVDNLFTVSVSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPAVHIH 301
MLTAVDNLFTVSVSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPAVHIH
Sbjct: 1 MLTAVDNLFTVSVSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPAVHIH 60
Query: 302 LPCVDLQETIPLEPTVKSLFHPKLAPG 382
LPCVDLQETIPLEPTVKSLFHPKLAPG
Sbjct: 61 LPCVDLQETIPLEPTVKSLFHPKLAPG 87
Score = 34.3 bits (75), Expect = 3.1
Identities = 13/19 (68%), Positives = 17/19 (89%)
Frame = +2
Query: 671 VEIEESSGNFDAYYDQSXQ 727
++++ SSGNFDAYYDQS Q
Sbjct: 184 LKLKSSSGNFDAYYDQSSQ 202
>UniRef50_UPI00015B4200 Cluster: PREDICTED: similar to mevalonate
kinase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar
to mevalonate kinase - Nasonia vitripennis
Length = 388
Score = 70.5 bits (165), Expect = 4e-11
Identities = 38/70 (54%), Positives = 49/70 (70%), Gaps = 1/70 (1%)
Frame = +2
Query: 158 VSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPA-VHIHLPCVDLQETIP 334
+SAPGKVIL GEHSVVYGKTA+A SLGLRSS+ E+ PHE +HI +P + + + +
Sbjct: 6 ISAPGKVILFGEHSVVYGKTAVAASLGLRSSLHFTEL--PHEECIIHIKMPKLGISKILS 63
Query: 335 LEPTVKSLFH 364
L V+ FH
Sbjct: 64 LH-QVEEDFH 72
Score = 50.8 bits (116), Expect = 3e-05
Identities = 28/88 (31%), Positives = 50/88 (56%)
Frame = +3
Query: 420 IDHDYHLRRVEEYLHLIKPNFDSLPNNQKNSLRSFLYVFSGIFGSTYLPVKSMDISMGSE 599
++HD +++++Y+ + F++ +Q+ S+ F Y + S L + S + + SE
Sbjct: 82 MNHDAINQKLQKYVATL--GFEN--PDQRLSMECFFYAMMQVIRSDQLRLSSFILELDSE 137
Query: 600 LTIGAGTGSSASFAVCLAGALIQLLKLK 683
L+IGAG GSSASF VCL + +L+
Sbjct: 138 LSIGAGAGSSASFTVCLVACFLHWSQLQ 165
>UniRef50_UPI0000587FA1 Cluster: PREDICTED: similar to Mevalonate
kinase (MK); n=2; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to Mevalonate kinase (MK) -
Strongylocentrotus purpuratus
Length = 413
Score = 65.7 bits (153), Expect = 1e-09
Identities = 29/60 (48%), Positives = 46/60 (76%)
Frame = +2
Query: 149 TVSVSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPAVHIHLPCVDLQET 328
++ +SAPGK+ILHGEH+VV+GKTA+A L LRS + +KE ++ +H++LP +DL+ +
Sbjct: 15 SIFISAPGKIILHGEHAVVHGKTALAAGLNLRSYLCLKEKDSGR---LHLNLPDIDLERS 71
Score = 39.5 bits (88), Expect = 0.083
Identities = 23/67 (34%), Positives = 37/67 (55%), Gaps = 1/67 (1%)
Frame = +3
Query: 480 FDSLPNNQKNSLRSFLYVFSGIFGST-YLPVKSMDISMGSELTIGAGTGSSASFAVCLAG 656
+ ++ ++ +FLY++ I G P+ +D + S L GAG GSSA+F+VCLA
Sbjct: 108 YSDTETTKRLAVMAFLYLYLCIAGRNGKFPI--LDTLVSSALPPGAGLGSSAAFSVCLAA 165
Query: 657 ALIQLLK 677
L+ K
Sbjct: 166 GLLTWAK 172
>UniRef50_A7SJK4 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 415
Score = 63.3 bits (147), Expect = 6e-09
Identities = 28/40 (70%), Positives = 36/40 (90%)
Frame = +2
Query: 143 LFTVSVSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIK 262
L V VSAPGK+ILHGEH+VVYGK AIAVS+GLR+++V++
Sbjct: 3 LSRVVVSAPGKIILHGEHAVVYGKAAIAVSIGLRTTVVLQ 42
Score = 33.5 bits (73), Expect = 5.4
Identities = 18/55 (32%), Positives = 36/55 (65%), Gaps = 1/55 (1%)
Frame = +3
Query: 504 KNSLRSFLYVF-SGIFGSTYLPVKSMDISMGSELTIGAGTGSSASFAVCLAGALI 665
K++ R FL++ S + LP ++++ + + L +GAG GSSA++++ LA A++
Sbjct: 110 KDAARVFLFLMTSTLRDRDRLP--AIEVEVKTALPLGAGLGSSAAYSISLAAAML 162
>UniRef50_UPI0000D56452 Cluster: PREDICTED: similar to mevalonate
kinase; n=3; Endopterygota|Rep: PREDICTED: similar to
mevalonate kinase - Tribolium castaneum
Length = 490
Score = 62.9 bits (146), Expect = 8e-09
Identities = 37/108 (34%), Positives = 61/108 (56%), Gaps = 1/108 (0%)
Frame = +3
Query: 387 TGKFSWRLPHKIDHDYHLRRVEEYLHLIKPNFDSLPNNQKNSLRSFLYVFSGIFGSTYLP 566
T ++ P +DHD VE+++ L + Q+ +L SF Y+F I GST
Sbjct: 172 TAYYNLTHPELLDHDKITEIVEKFVDLNRHE-----PKQRQALVSFFYLFFAIVGSTDSN 226
Query: 567 VKS-MDISMGSELTIGAGTGSSASFAVCLAGALIQLLKLKSLRGISMH 707
+ +++ S+LT+GAGTGSSASFAV +A L+ +K+K + +++
Sbjct: 227 LSDGFKLAVRSDLTVGAGTGSSASFAVAIAAFLLHFVKVKKFKSKNLY 274
Score = 56.4 bits (130), Expect = 7e-07
Identities = 26/37 (70%), Positives = 30/37 (81%)
Frame = +2
Query: 143 LFTVSVSAPGKVILHGEHSVVYGKTAIAVSLGLRSSI 253
L + VSAPGKVILHGEHSVVY K A+A SLGLR+ +
Sbjct: 95 LSEIRVSAPGKVILHGEHSVVYDKLAVAASLGLRTRL 131
>UniRef50_UPI0000E810F5 Cluster: PREDICTED: hypothetical protein;
n=1; Gallus gallus|Rep: PREDICTED: hypothetical protein
- Gallus gallus
Length = 527
Score = 56.8 bits (131), Expect = 5e-07
Identities = 29/55 (52%), Positives = 40/55 (72%)
Frame = +2
Query: 158 VSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPAVHIHLPCVDLQ 322
VSAPGKVILHGEH+VV+GK A+AV+LGLR+ + ++ + IHLP V ++
Sbjct: 181 VSAPGKVILHGEHAVVHGKAALAVALGLRTFLRLRPGGGER---LRIHLPGVGVR 232
Score = 49.2 bits (112), Expect = 1e-04
Identities = 26/52 (50%), Positives = 37/52 (71%)
Frame = +3
Query: 510 SLRSFLYVFSGIFGSTYLPVKSMDISMGSELTIGAGTGSSASFAVCLAGALI 665
++ +FLY+ I + Y V S+DI++ SEL GAG GSSA++AVCLA AL+
Sbjct: 312 AILAFLYMCLAI-SAKYGDVPSVDIAVWSELPTGAGLGSSAAYAVCLAAALL 362
>UniRef50_UPI000155619E Cluster: PREDICTED: hypothetical protein,
partial; n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
hypothetical protein, partial - Ornithorhynchus anatinus
Length = 282
Score = 55.2 bits (127), Expect = 2e-06
Identities = 29/60 (48%), Positives = 40/60 (66%)
Frame = +2
Query: 149 TVSVSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPAVHIHLPCVDLQET 328
T+ VSAPGK ILHGEHSVV+GK A+AV+L LR+ + + + V + LP + L+ T
Sbjct: 5 TLVVSAPGKAILHGEHSVVHGKVALAVALNLRTFL---QFRPGDQDRVTVSLPNLGLRRT 61
Score = 41.5 bits (93), Expect = 0.021
Identities = 27/88 (30%), Positives = 46/88 (52%)
Frame = +3
Query: 411 PHKIDHDYHLRRVEEYLHLIKPNFDSLPNNQKNSLRSFLYVFSGIFGSTYLPVKSMDISM 590
P + + +++E+ L DS Q +L +FLY+++ I G T +D+++
Sbjct: 144 PSAVPTPERMEKLKEFAGLAPGPLDS----QGLALLAFLYLYTAI-GGTDGAWPGVDVTV 198
Query: 591 GSELTIGAGTGSSASFAVCLAGALIQLL 674
SEL G G GSSA+++ C A A + L
Sbjct: 199 WSELPPGGGLGSSAAYSACSASAWLSAL 226
>UniRef50_Q65XX9 Cluster: Putative uncharacterized protein; n=5;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 614
Score = 54.8 bits (126), Expect = 2e-06
Identities = 28/66 (42%), Positives = 46/66 (69%)
Frame = +2
Query: 158 VSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPAVHIHLPCVDLQETIPL 337
VSAPGK+IL GEH+VVYG+TAIA S+ LR+ + + T + +++ LP + +++T L
Sbjct: 144 VSAPGKIILFGEHAVVYGRTAIAGSIDLRTYV---SLYTSADGRIYLSLPDLGVEKTWML 200
Query: 338 EPTVKS 355
+ +K+
Sbjct: 201 KDLLKA 206
>UniRef50_A3LQ81 Cluster: Mevalonate kinase; n=5;
Saccharomycetales|Rep: Mevalonate kinase - Pichia
stipitis (Yeast)
Length = 432
Score = 54.8 bits (126), Expect = 2e-06
Identities = 33/92 (35%), Positives = 51/92 (55%), Gaps = 5/92 (5%)
Frame = +2
Query: 158 VSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPAVHIHLPCVDL-----Q 322
VSAPGKVI+ GEHS VYGK AIA +L LR+ +++ P +++ P ++L +
Sbjct: 7 VSAPGKVIIFGEHSAVYGKPAIAAALSLRAYLLVTPSQDP--DTINLSFPDINLTHSWNK 64
Query: 323 ETIPLEPTVKSLFHPKLAPGDNRQILLEITPQ 418
IP + VK + P + +++ EI Q
Sbjct: 65 NDIPWDSIVKHINLVDNLPQTSEELVPEIVDQ 96
Score = 38.3 bits (85), Expect = 0.19
Identities = 22/47 (46%), Positives = 28/47 (59%)
Frame = +3
Query: 522 FLYVFSGIFGSTYLPVKSMDISMGSELTIGAGTGSSASFAVCLAGAL 662
FLY+++ + + M + S L IGAG GSSAS AVCLA AL
Sbjct: 116 FLYLYTHLCNQE---LAGMSFCIRSTLPIGAGLGSSASTAVCLASAL 159
>UniRef50_Q03426 Cluster: Mevalonate kinase; n=26; Euteleostomi|Rep:
Mevalonate kinase - Homo sapiens (Human)
Length = 396
Score = 54.4 bits (125), Expect = 3e-06
Identities = 29/56 (51%), Positives = 40/56 (71%), Gaps = 1/56 (1%)
Frame = +2
Query: 158 VSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPA-VHIHLPCVDLQ 322
VSAPGKVILHGEH+VV+GK A+AVSL LR+ + ++ PH V + LP + ++
Sbjct: 8 VSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQ----PHSNGKVDLSLPNIGIK 59
Score = 43.6 bits (98), Expect = 0.005
Identities = 24/61 (39%), Positives = 38/61 (62%)
Frame = +3
Query: 483 DSLPNNQKNSLRSFLYVFSGIFGSTYLPVKSMDISMGSELTIGAGTGSSASFAVCLAGAL 662
D ++ ++ +FLY++ I + S+DI + SEL GAG GSSA+++VCLA AL
Sbjct: 99 DDCAVTERLAVLAFLYLYLSICRKQRA-LPSLDIVVWSELPPGAGLGSSAAYSVCLAAAL 157
Query: 663 I 665
+
Sbjct: 158 L 158
>UniRef50_Q6CEF6 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome B of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 449
Score = 53.6 bits (123), Expect = 5e-06
Identities = 25/61 (40%), Positives = 39/61 (63%)
Frame = +2
Query: 158 VSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPAVHIHLPCVDLQETIPL 337
+SAPGKVIL GEH+ V+GK AIA ++ LR+ +++ E T P V + P + L + +
Sbjct: 5 ISAPGKVILFGEHAAVFGKPAIAAAIDLRTYLLV-ETTTSDTPTVTLEFPDIHLNFKVQV 63
Query: 338 E 340
+
Sbjct: 64 D 64
Score = 37.1 bits (82), Expect = 0.44
Identities = 30/91 (32%), Positives = 45/91 (49%)
Frame = +3
Query: 399 SWRLPHKIDHDYHLRRVEEYLHLIKPNFDSLPNNQKNSLRSFLYVFSGIFGSTYLPVKSM 578
+W P +D H+ L L++ L Q+ ++ SFLY++ + + S
Sbjct: 79 NWSTPKTLDK--HIFDSLSSLALLEE--PGLTKVQQAAVVSFLYLYIHLCPPSVCEDSSN 134
Query: 579 DISMGSELTIGAGTGSSASFAVCLAGALIQL 671
+ + S L IGAG GSSAS VCLA L+ L
Sbjct: 135 WV-VRSTLPIGAGLGSSASICVCLAAGLLVL 164
>UniRef50_UPI0000DB6B27 Cluster: PREDICTED: similar to Mevalonate
kinase (MK); n=1; Apis mellifera|Rep: PREDICTED: similar
to Mevalonate kinase (MK) - Apis mellifera
Length = 359
Score = 52.4 bits (120), Expect = 1e-05
Identities = 24/37 (64%), Positives = 30/37 (81%)
Frame = +2
Query: 158 VSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEV 268
VSAPGKVIL GEH+VVYGKTA+A S+ LR+ + E+
Sbjct: 6 VSAPGKVILFGEHAVVYGKTAVAASIDLRTVLNFTEL 42
Score = 48.8 bits (111), Expect = 1e-04
Identities = 24/55 (43%), Positives = 31/55 (56%)
Frame = +3
Query: 501 QKNSLRSFLYVFSGIFGSTYLPVKSMDISMGSELTIGAGTGSSASFAVCLAGALI 665
QK SL +F Y I + +K I + +EL I +G GSSASFAVCLA +
Sbjct: 81 QKLSLEAFFYTLIYIAQKEEMEIKPFQIQLNTELAINSGLGSSASFAVCLAACFV 135
>UniRef50_Q7PWI8 Cluster: ENSANGP00000021364; n=2; Culicidae|Rep:
ENSANGP00000021364 - Anopheles gambiae str. PEST
Length = 402
Score = 51.6 bits (118), Expect = 2e-05
Identities = 24/30 (80%), Positives = 26/30 (86%)
Frame = +2
Query: 158 VSAPGKVILHGEHSVVYGKTAIAVSLGLRS 247
VSAPGKVILHGEHSVVYG AIA S+GL +
Sbjct: 11 VSAPGKVILHGEHSVVYGHPAIAGSIGLHT 40
Score = 40.7 bits (91), Expect = 0.036
Identities = 18/33 (54%), Positives = 25/33 (75%)
Frame = +3
Query: 582 ISMGSELTIGAGTGSSASFAVCLAGALIQLLKL 680
+S+ SE++IGAG GSSAS+ VCLA QL ++
Sbjct: 143 LSLYSEMSIGAGLGSSASYGVCLAAGAYQLSRI 175
>UniRef50_Q0UWF5 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 526
Score = 51.6 bits (118), Expect = 2e-05
Identities = 24/57 (42%), Positives = 39/57 (68%)
Frame = +2
Query: 158 VSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPAVHIHLPCVDLQET 328
VSAPGKVI++GEH+VV+GK AIA ++ LRS + + ++ + V + P + ++ T
Sbjct: 37 VSAPGKVIVYGEHAVVHGKAAIAAAISLRSYLHVSFLSKSNR-TVKLRFPDIQMEHT 92
Score = 41.1 bits (92), Expect = 0.027
Identities = 30/102 (29%), Positives = 54/102 (52%), Gaps = 1/102 (0%)
Frame = +3
Query: 393 KFSWRLPHKIDHDYHLRRVEEYLHLIKPNF-DSLPNNQKNSLRSFLYVFSGIFGSTYLPV 569
K+ + L +D D + ++ ++ + P +S+ S SFLY+F + P
Sbjct: 110 KYYYDLVTSLDPDL-MAAIQPFIDEVSPKAPESVRKIHHASACSFLYLFLSLASRKTPPC 168
Query: 570 KSMDISMGSELTIGAGTGSSASFAVCLAGALIQLLKLKSLRG 695
++ S + IGAG GSSAS +VCL+ A+ L+++++L G
Sbjct: 169 I---YTLRSTIPIGAGLGSSASISVCLSAAM--LMQIRALSG 205
>UniRef50_Q4WP25 Cluster: Mevalonate kinase; n=15;
Pezizomycotina|Rep: Mevalonate kinase - Aspergillus
fumigatus (Sartorya fumigata)
Length = 538
Score = 50.0 bits (114), Expect = 6e-05
Identities = 24/69 (34%), Positives = 44/69 (63%)
Frame = +2
Query: 158 VSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPAVHIHLPCVDLQETIPL 337
VSAPGKVI++GEH+VV+GK A+A ++ LRS +++ + + + + ++ + L T +
Sbjct: 94 VSAPGKVIVYGEHAVVHGKAAMAAAISLRSYLLVTTL-SKSQRTITMNFRDIGLDHTWNI 152
Query: 338 EPTVKSLFH 364
+ +FH
Sbjct: 153 DELPWDVFH 161
Score = 44.0 bits (99), Expect = 0.004
Identities = 33/109 (30%), Positives = 58/109 (53%), Gaps = 1/109 (0%)
Frame = +3
Query: 372 WHQGITGKFSWRLPHKIDHDYHLRRVEEYLHLIKPNF-DSLPNNQKNSLRSFLYVFSGIF 548
+H KF + L +D + + ++ + + P+ + + + S +FLY+F +
Sbjct: 160 FHHPSKKKFYYDLVTSLDPEL-VAAIQPHADAVSPDKPEDVRKIHRRSASAFLYLFLSL- 217
Query: 549 GSTYLPVKSMDISMGSELTIGAGTGSSASFAVCLAGALIQLLKLKSLRG 695
GS+ P ++ S + IGAG GSSAS VCL+ AL LL++++L G
Sbjct: 218 GSSQNP--GAIYTLRSTIPIGAGLGSSASVCVCLSAAL--LLQIRTLAG 262
>UniRef50_Q86AG7 Cluster: Similar to Rattus norvegicus (Rat).
Mevalonate kinase; n=2; Dictyostelium discoideum|Rep:
Similar to Rattus norvegicus (Rat). Mevalonate kinase -
Dictyostelium discoideum (Slime mold)
Length = 390
Score = 49.2 bits (112), Expect = 1e-04
Identities = 24/44 (54%), Positives = 34/44 (77%)
Frame = +2
Query: 122 MLTAVDNLFTVSVSAPGKVILHGEHSVVYGKTAIAVSLGLRSSI 253
M++ DN+ + VSAPGK+IL GEH+VV KTAIA +L LR+++
Sbjct: 1 MISNQDNI--IQVSAPGKIILFGEHAVVLEKTAIASALSLRTTV 42
Score = 37.9 bits (84), Expect = 0.25
Identities = 20/52 (38%), Positives = 32/52 (61%)
Frame = +3
Query: 513 LRSFLYVFSGIFGSTYLPVKSMDISMGSELTIGAGTGSSASFAVCLAGALIQ 668
+ +FL++F + T K+ +I + S+L IGAG GSSASF V + L++
Sbjct: 107 IHTFLFLFCALTKCT----KAYNIKITSDLPIGAGLGSSASFCVSICAGLLK 154
>UniRef50_Q4TG59 Cluster: Chromosome undetermined SCAF3891, whole
genome shotgun sequence; n=2; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF3891,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 173
Score = 48.8 bits (111), Expect = 1e-04
Identities = 29/62 (46%), Positives = 40/62 (64%), Gaps = 7/62 (11%)
Frame = +2
Query: 152 VSVSAPGKVILHGEHSVVYGKT-------AIAVSLGLRSSIVIKEVNTPHEPAVHIHLPC 310
+ VSAPGK ILHGEH+VV+GK A+AVSL LRS + ++ +T V ++LP
Sbjct: 1 IYVSAPGKAILHGEHAVVHGKVTSNKAKMALAVSLNLRSYLRLEATST---GTVGVNLPN 57
Query: 311 VD 316
+D
Sbjct: 58 ID 59
Score = 44.0 bits (99), Expect = 0.004
Identities = 26/64 (40%), Positives = 36/64 (56%)
Frame = +3
Query: 474 PNFDSLPNNQKNSLRSFLYVFSGIFGSTYLPVKSMDISMGSELTIGAGTGSSASFAVCLA 653
PN D+ + + L+ F SG T L + +S+ SEL GAG GSSA++ VCLA
Sbjct: 56 PNIDTFLHWNLSELKQFAPSVSGNEQLT-LGAAQLTVSVWSELPTGAGLGSSAAYTVCLA 114
Query: 654 GALI 665
AL+
Sbjct: 115 AALL 118
>UniRef50_A2SR97 Cluster: Mevalonate kinase; n=4;
Methanomicrobiales|Rep: Mevalonate kinase -
Methanocorpusculum labreanum (strain ATCC 43576 / DSM
4855 / Z)
Length = 290
Score = 47.6 bits (108), Expect = 3e-04
Identities = 22/42 (52%), Positives = 29/42 (69%)
Frame = +2
Query: 161 SAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEP 286
SAPGKVIL GEHSVVYGK AIA+++ R + ++ +P
Sbjct: 5 SAPGKVILFGEHSVVYGKPAIAMAIKPRVQVTVRHSRYYQKP 46
>UniRef50_Q09780 Cluster: Putative mevalonate kinase; n=1;
Schizosaccharomyces pombe|Rep: Putative mevalonate
kinase - Schizosaccharomyces pombe (Fission yeast)
Length = 404
Score = 47.2 bits (107), Expect = 4e-04
Identities = 21/38 (55%), Positives = 28/38 (73%)
Frame = +2
Query: 158 VSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVN 271
VS+PGK IL GEH+VVYG TA+A ++ LRS ++ N
Sbjct: 7 VSSPGKTILFGEHAVVYGATALAAAVSLRSYCKLQTTN 44
Score = 35.1 bits (77), Expect = 1.8
Identities = 19/69 (27%), Positives = 38/69 (55%)
Frame = +3
Query: 459 LHLIKPNFDSLPNNQKNSLRSFLYVFSGIFGSTYLPVKSMDISMGSELTIGAGTGSSASF 638
L L++ + L N + + S + +F S P + +++ S++ +GAG GSSA+
Sbjct: 85 LDLLQGLGELLKNEENGLIHSAMLCTLYLFTSLSSPSQGCTLTISSQVPLGAGLGSSATI 144
Query: 639 AVCLAGALI 665
+V +A +L+
Sbjct: 145 SVVVATSLL 153
>UniRef50_Q8TT37 Cluster: Mevalonate kinase; n=5; Euryarchaeota|Rep:
Mevalonate kinase - Methanosarcina acetivorans
Length = 305
Score = 46.4 bits (105), Expect = 7e-04
Identities = 19/37 (51%), Positives = 29/37 (78%)
Frame = +2
Query: 152 VSVSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIK 262
+S SAPGK+ L GEH+VVYG+TAI ++ LR+ + ++
Sbjct: 6 ISCSAPGKIYLFGEHAVVYGETAIGCAIELRTRVRVE 42
>UniRef50_P07277 Cluster: Mevalonate kinase; n=3;
Saccharomycetales|Rep: Mevalonate kinase - Saccharomyces
cerevisiae (Baker's yeast)
Length = 443
Score = 46.0 bits (104), Expect = 0.001
Identities = 22/40 (55%), Positives = 29/40 (72%), Gaps = 1/40 (2%)
Frame = +2
Query: 161 SAPGKVILHGEHSVVYGKTAIAVSL-GLRSSIVIKEVNTP 277
SAPGKVI+ GEHS VY K A+A S+ LR+ ++I E + P
Sbjct: 8 SAPGKVIIFGEHSAVYNKPAVAASVSALRTYLLISESSAP 47
Score = 33.5 bits (73), Expect = 5.4
Identities = 18/34 (52%), Positives = 23/34 (67%)
Frame = +3
Query: 570 KSMDISMGSELTIGAGTGSSASFAVCLAGALIQL 671
K++ S+ S L IGAG GSSAS +V LA A+ L
Sbjct: 130 KNIKFSLKSTLPIGAGLGSSASISVSLALAMAYL 163
>UniRef50_Q50559 Cluster: Mevalonate kinase; n=2;
Methanothermobacter thermautotrophicus str. Delta H|Rep:
Mevalonate kinase - Methanobacterium thermoautotrophicum
Length = 303
Score = 46.0 bits (104), Expect = 0.001
Identities = 20/42 (47%), Positives = 28/42 (66%)
Frame = +2
Query: 155 SVSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPH 280
S SAP K IL GEH+VVY K AIA ++ R ++ + E ++ H
Sbjct: 4 SASAPAKAILFGEHAVVYSKPAIAAAIDRRVTVTVSESSSTH 45
>UniRef50_Q0LHN3 Cluster: Mevalonate kinase; n=2; Chloroflexi
(class)|Rep: Mevalonate kinase - Herpetosiphon
aurantiacus ATCC 23779
Length = 313
Score = 45.6 bits (103), Expect = 0.001
Identities = 23/54 (42%), Positives = 36/54 (66%), Gaps = 1/54 (1%)
Frame = +2
Query: 161 SAPGKVILHGEHSVVYGKTAIAVSL-GLRSSIVIKEVNTPHEPAVHIHLPCVDL 319
SAPGK+IL GEH+VVYG+ A+A+ + LR+S+ ++ P + +H P + L
Sbjct: 3 SAPGKLILAGEHAVVYGQPALAMPIAALRASVAVEP--APRGAGMTVHAPDLGL 54
>UniRef50_Q7K2V9 Cluster: GH04687p; n=1; Drosophila
melanogaster|Rep: GH04687p - Drosophila melanogaster
(Fruit fly)
Length = 390
Score = 45.6 bits (103), Expect = 0.001
Identities = 27/83 (32%), Positives = 44/83 (53%)
Frame = +2
Query: 158 VSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPAVHIHLPCVDLQETIPL 337
V +PGKVILHGEH+VVY + A+A +GL +++ +++ + + L+ +P
Sbjct: 6 VHSPGKVILHGEHAVVYHRPALAAVVGLGTTLRFRQLEDSQVASFQLEALNCTLEIQLPE 65
Query: 338 EPTVKSLFHPKLAPGDNRQILLE 406
+ F K P D+ LLE
Sbjct: 66 FNGFLAEFRSKY-PSDSTANLLE 87
Score = 33.5 bits (73), Expect = 5.4
Identities = 15/30 (50%), Positives = 20/30 (66%)
Frame = +3
Query: 582 ISMGSELTIGAGTGSSASFAVCLAGALIQL 671
+ + S+LT+GAG GSSASF LA + L
Sbjct: 141 VQVDSQLTVGAGLGSSASFGAALATTFLIL 170
>UniRef50_A0B6E3 Cluster: Mevalonate kinase; n=1; Methanosaeta
thermophila PT|Rep: Mevalonate kinase - Methanosaeta
thermophila (strain DSM 6194 / PT)
(Methanothrixthermophila (strain DSM 6194 / PT))
Length = 321
Score = 45.6 bits (103), Expect = 0.001
Identities = 19/47 (40%), Positives = 33/47 (70%)
Frame = +2
Query: 155 SVSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPAVH 295
+ SAPGKVIL GEH+VV G A+ ++ LR+ ++++++ E ++H
Sbjct: 3 AASAPGKVILFGEHAVVSGAPALGTAIDLRARVLVEDLPGKTEISIH 49
>UniRef50_Q9V187 Cluster: Mevalonate kinase; n=4;
Thermococcaceae|Rep: Mevalonate kinase - Pyrococcus
abyssi
Length = 335
Score = 45.6 bits (103), Expect = 0.001
Identities = 21/34 (61%), Positives = 26/34 (76%)
Frame = +2
Query: 152 VSVSAPGKVILHGEHSVVYGKTAIAVSLGLRSSI 253
V SAP K+IL GEHSVVYGK AIA ++ LR+ +
Sbjct: 5 VLASAPAKIILFGEHSVVYGKPAIASAIDLRTYV 38
Score = 35.5 bits (78), Expect = 1.3
Identities = 16/36 (44%), Positives = 26/36 (72%)
Frame = +3
Query: 576 MDISMGSELTIGAGTGSSASFAVCLAGALIQLLKLK 683
+ +S+ S++ +GAG GSSA+ AV GA+ +LL L+
Sbjct: 102 VSVSITSQIPVGAGLGSSAAVAVATIGAVSKLLDLE 137
>UniRef50_Q58487 Cluster: Mevalonate kinase; n=1; Methanocaldococcus
jannaschii|Rep: Mevalonate kinase - Methanococcus
jannaschii
Length = 312
Score = 44.4 bits (100), Expect = 0.003
Identities = 20/36 (55%), Positives = 27/36 (75%)
Frame = +2
Query: 158 VSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKE 265
+ P KVIL GEH+VVYG AI++++ L S+I IKE
Sbjct: 3 IETPSKVILFGEHAVVYGYRAISMAIDLTSTIEIKE 38
>UniRef50_Q756D2 Cluster: AER335Wp; n=3; Saccharomycetaceae|Rep:
AER335Wp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 428
Score = 44.0 bits (99), Expect = 0.004
Identities = 23/54 (42%), Positives = 31/54 (57%)
Frame = +2
Query: 161 SAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPAVHIHLPCVDLQ 322
SAPGKVI+ GEHS VY K AIA S+ + + E + + AV + P + Q
Sbjct: 19 SAPGKVIIFGEHSAVYNKPAIAASVSSLRTYLFVEADAESD-AVRMEFPDIGFQ 71
Score = 36.7 bits (81), Expect = 0.58
Identities = 22/50 (44%), Positives = 32/50 (64%)
Frame = +3
Query: 522 FLYVFSGIFGSTYLPVKSMDISMGSELTIGAGTGSSASFAVCLAGALIQL 671
FLY+++ + V+ + ++ S L IGAG GSSAS AVCLA A+ +L
Sbjct: 123 FLYIYTCLCRE----VQGVRFTVKSTLPIGAGLGSSASIAVCLALAMGRL 168
>UniRef50_O27995 Cluster: Mevalonate kinase; n=1; Archaeoglobus
fulgidus|Rep: Mevalonate kinase - Archaeoglobus fulgidus
Length = 284
Score = 44.0 bits (99), Expect = 0.004
Identities = 17/35 (48%), Positives = 27/35 (77%)
Frame = +2
Query: 161 SAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKE 265
SAPGK+IL GEH+VVYG+ A+ ++ LR + +++
Sbjct: 4 SAPGKIILFGEHAVVYGRHAVVSAINLRCRVSVRK 38
>UniRef50_UPI000155611C Cluster: PREDICTED: hypothetical protein,
partial; n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
hypothetical protein, partial - Ornithorhynchus anatinus
Length = 269
Score = 43.6 bits (98), Expect = 0.005
Identities = 27/85 (31%), Positives = 46/85 (54%)
Frame = +3
Query: 411 PHKIDHDYHLRRVEEYLHLIKPNFDSLPNNQKNSLRSFLYVFSGIFGSTYLPVKSMDISM 590
P + + +++E+ L DS Q +L +FLY+++ I G T +D+++
Sbjct: 68 PSAVPTPEQMEKLKEFAGLAPGPLDS----QGLALLAFLYLYTAI-GGTDGAWPGVDVTV 122
Query: 591 GSELTIGAGTGSSASFAVCLAGALI 665
SEL G G GSSA+++ CLA L+
Sbjct: 123 WSELPPGGGLGSSAAYSACLAACLL 147
>UniRef50_Q9HQI6 Cluster: Mevalonate kinase; n=5;
Halobacteriaceae|Rep: Mevalonate kinase - Halobacterium
salinarium (Halobacterium halobium)
Length = 330
Score = 43.2 bits (97), Expect = 0.007
Identities = 18/39 (46%), Positives = 27/39 (69%)
Frame = +2
Query: 149 TVSVSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKE 265
T + SAPGKV L GEH+VVYG+ A+ ++ R+ + + E
Sbjct: 2 TTTSSAPGKVYLFGEHAVVYGEPAVPCAIERRAHVTVSE 40
>UniRef50_Q2HTL9 Cluster: Mevalonate and galactokinase; n=5; core
eudicotyledons|Rep: Mevalonate and galactokinase -
Medicago truncatula (Barrel medic)
Length = 388
Score = 42.7 bits (96), Expect = 0.009
Identities = 20/42 (47%), Positives = 30/42 (71%)
Frame = +2
Query: 152 VSVSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTP 277
V APGK+IL GEH+VV+G TA+A S+ L + + ++ +TP
Sbjct: 3 VKARAPGKIILAGEHAVVHGSTAVASSIDLYTYVSLR-FSTP 43
Score = 35.9 bits (79), Expect = 1.0
Identities = 19/53 (35%), Positives = 32/53 (60%)
Frame = +3
Query: 507 NSLRSFLYVFSGIFGSTYLPVKSMDISMGSELTIGAGTGSSASFAVCLAGALI 665
+ + +FL+++S I G K + + S+L +G+G GSSA+F V LA A +
Sbjct: 113 SGVAAFLWLYSSIQG-----FKPATVVINSDLPLGSGLGSSAAFCVALAAAFL 160
>UniRef50_A1RYL2 Cluster: Mevalonate kinase; n=1; Thermofilum
pendens Hrk 5|Rep: Mevalonate kinase - Thermofilum
pendens (strain Hrk 5)
Length = 322
Score = 42.7 bits (96), Expect = 0.009
Identities = 19/38 (50%), Positives = 27/38 (71%)
Frame = +2
Query: 161 SAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNT 274
SAP KVIL GEH VV G+ AIA ++ LR+ + ++ +T
Sbjct: 7 SAPAKVILFGEHFVVEGQPAIAAAISLRAHVTVEPADT 44
>UniRef50_P46086 Cluster: Mevalonate kinase; n=8; Magnoliophyta|Rep:
Mevalonate kinase - Arabidopsis thaliana (Mouse-ear
cress)
Length = 378
Score = 42.7 bits (96), Expect = 0.009
Identities = 17/37 (45%), Positives = 27/37 (72%)
Frame = +2
Query: 152 VSVSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIK 262
V APGK+IL GEH+VV+G TA+A ++ L + + ++
Sbjct: 3 VKARAPGKIILAGEHAVVHGSTAVAAAIDLYTYVTLR 39
>UniRef50_A5UV63 Cluster: Mevalonate kinase; n=3;
Chloroflexaceae|Rep: Mevalonate kinase - Roseiflexus sp.
RS-1
Length = 314
Score = 41.9 bits (94), Expect = 0.016
Identities = 18/25 (72%), Positives = 22/25 (88%)
Frame = +2
Query: 161 SAPGKVILHGEHSVVYGKTAIAVSL 235
SAPGK+IL GEH+VVYG+ AIA+ L
Sbjct: 4 SAPGKIILCGEHAVVYGRPAIAIPL 28
>UniRef50_A2E1U7 Cluster: Mevalonate kinase family protein; n=1;
Trichomonas vaginalis G3|Rep: Mevalonate kinase family
protein - Trichomonas vaginalis G3
Length = 315
Score = 40.7 bits (91), Expect = 0.036
Identities = 18/30 (60%), Positives = 23/30 (76%)
Frame = +2
Query: 155 SVSAPGKVILHGEHSVVYGKTAIAVSLGLR 244
S S PGKVIL GEH+VVYG+ A+A ++ R
Sbjct: 5 SFSFPGKVILFGEHAVVYGEAAVASAISRR 34
>UniRef50_A7DRD8 Cluster: Mevalonate kinase; n=1; Candidatus
Nitrosopumilus maritimus SCM1|Rep: Mevalonate kinase -
Candidatus Nitrosopumilus maritimus SCM1
Length = 313
Score = 40.7 bits (91), Expect = 0.036
Identities = 18/37 (48%), Positives = 26/37 (70%)
Frame = +2
Query: 161 SAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVN 271
SAPGKVIL GEH VVYG AI ++ R ++ ++++
Sbjct: 6 SAPGKVILFGEHFVVYGVKAILCAINKRIAVTAEKID 42
>UniRef50_UPI00015BB033 Cluster: mevalonate kinase; n=1; Ignicoccus
hospitalis KIN4/I|Rep: mevalonate kinase - Ignicoccus
hospitalis KIN4/I
Length = 321
Score = 39.9 bits (89), Expect = 0.063
Identities = 19/29 (65%), Positives = 21/29 (72%)
Frame = +2
Query: 149 TVSVSAPGKVILHGEHSVVYGKTAIAVSL 235
+VS AP KV L GEHSVVYGK AI S+
Sbjct: 2 SVSARAPTKVTLFGEHSVVYGKPAIVFSM 30
>UniRef50_Q2NG06 Cluster: Putative mevalonate kinase; n=1;
Methanosphaera stadtmanae DSM 3091|Rep: Putative
mevalonate kinase - Methanosphaera stadtmanae (strain
DSM 3091)
Length = 322
Score = 39.9 bits (89), Expect = 0.063
Identities = 17/28 (60%), Positives = 22/28 (78%)
Frame = +2
Query: 152 VSVSAPGKVILHGEHSVVYGKTAIAVSL 235
+ APGK+IL GEH+VVY K AIAV++
Sbjct: 3 IKAFAPGKIILFGEHTVVYKKPAIAVAI 30
>UniRef50_A5UN66 Cluster: Mevalonate kinase; n=1; Methanobrevibacter
smithii ATCC 35061|Rep: Mevalonate kinase -
Methanobrevibacter smithii (strain PS / ATCC 35061 / DSM
861)
Length = 320
Score = 39.9 bits (89), Expect = 0.063
Identities = 20/38 (52%), Positives = 25/38 (65%)
Frame = +2
Query: 161 SAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNT 274
SAP K IL GEHSVVY + AIA ++ R+ + I E T
Sbjct: 6 SAPAKTILFGEHSVVYDEPAIAGAVNKRAYVEITESKT 43
>UniRef50_A3H636 Cluster: Mevalonate kinase; n=1; Caldivirga
maquilingensis IC-167|Rep: Mevalonate kinase -
Caldivirga maquilingensis IC-167
Length = 334
Score = 39.9 bits (89), Expect = 0.063
Identities = 17/38 (44%), Positives = 27/38 (71%)
Frame = +2
Query: 152 VSVSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKE 265
V+ +APG V L GEH+VVYG+ AIA+++ + ++E
Sbjct: 6 VTATAPGVVKLFGEHAVVYGRPAIAMAINKGIKVTVEE 43
>UniRef50_Q74JA4 Cluster: Mevalonate kinase; n=7; Lactobacillus|Rep:
Mevalonate kinase - Lactobacillus johnsonii
Length = 305
Score = 39.5 bits (88), Expect = 0.083
Identities = 20/43 (46%), Positives = 28/43 (65%), Gaps = 1/43 (2%)
Frame = +2
Query: 152 VSVSAPGKVILHGEHSVVYGKTAIAVSL-GLRSSIVIKEVNTP 277
+ V A GKVIL GEHSVVYG A+A+ + L + ++E + P
Sbjct: 5 IEVKAHGKVILIGEHSVVYGYDALALPIQALNITTTVEETDGP 47
>UniRef50_Q2BIK0 Cluster: Mevalonate kinase, putative; n=1;
Neptuniibacter caesariensis|Rep: Mevalonate kinase,
putative - Neptuniibacter caesariensis
Length = 327
Score = 39.5 bits (88), Expect = 0.083
Identities = 17/33 (51%), Positives = 24/33 (72%)
Frame = +2
Query: 152 VSVSAPGKVILHGEHSVVYGKTAIAVSLGLRSS 250
+ APGK+IL GEHSVVYG AIA ++ +++
Sbjct: 1 MKAQAPGKLILSGEHSVVYGAPAIATAVAQQAT 33
>UniRef50_Q8TWN9 Cluster: Mevalonate kinase; n=1; Methanopyrus
kandleri|Rep: Mevalonate kinase - Methanopyrus kandleri
Length = 328
Score = 39.1 bits (87), Expect = 0.11
Identities = 18/28 (64%), Positives = 22/28 (78%)
Frame = +2
Query: 152 VSVSAPGKVILHGEHSVVYGKTAIAVSL 235
+SV AP K IL GEH+VVYG A+AV+L
Sbjct: 3 ISVKAPLKAILAGEHAVVYGYPAVAVAL 30
>UniRef50_A2BL67 Cluster: Mevalonate kinase; n=1; Hyperthermus
butylicus DSM 5456|Rep: Mevalonate kinase - Hyperthermus
butylicus (strain DSM 5456 / JCM 9403)
Length = 316
Score = 38.7 bits (86), Expect = 0.14
Identities = 17/29 (58%), Positives = 23/29 (79%)
Frame = +2
Query: 161 SAPGKVILHGEHSVVYGKTAIAVSLGLRS 247
SAP KVI+ GEH VV+G A+A ++GLR+
Sbjct: 6 SAPAKVIVFGEHWVVHGGLALAAAIGLRA 34
>UniRef50_Q9Y946 Cluster: Mevalonate kinase; n=1; Aeropyrum
pernix|Rep: Mevalonate kinase - Aeropyrum pernix
Length = 324
Score = 38.7 bits (86), Expect = 0.14
Identities = 17/34 (50%), Positives = 23/34 (67%)
Frame = +2
Query: 161 SAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIK 262
SAPGKVI+ GEH VV G AI ++G R + ++
Sbjct: 8 SAPGKVIIVGEHFVVRGSLAIVAAIGRRLRVTVR 41
>UniRef50_Q8L1I1 Cluster: Phosphomevalonate kinase; n=1; Paracoccus
zeaxanthinifaciens|Rep: Phosphomevalonate kinase -
Paracoccus zeaxanthinifaciens
Length = 305
Score = 38.3 bits (85), Expect = 0.19
Identities = 16/36 (44%), Positives = 23/36 (63%)
Frame = +2
Query: 152 VSVSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVI 259
+ SAPG V++ GEH+VVYG AI + R+ + I
Sbjct: 5 IRASAPGSVMITGEHAVVYGHRAIVAGIEQRAHVTI 40
>UniRef50_A6G140 Cluster: Hydroxymethylglutaryl-CoA reductase; n=1;
Plesiocystis pacifica SIR-1|Rep:
Hydroxymethylglutaryl-CoA reductase - Plesiocystis
pacifica SIR-1
Length = 810
Score = 38.3 bits (85), Expect = 0.19
Identities = 16/34 (47%), Positives = 26/34 (76%)
Frame = +2
Query: 146 FTVSVSAPGKVILHGEHSVVYGKTAIAVSLGLRS 247
+T +VSAPGK L GE++V+YG +AI ++ +R+
Sbjct: 43 YTGTVSAPGKAFLIGEYAVLYGHSAIVTAVDVRA 76
>UniRef50_Q8L1I2 Cluster: Mevalonate kinase; n=1; Paracoccus
zeaxanthinifaciens|Rep: Mevalonate kinase - Paracoccus
zeaxanthinifaciens
Length = 378
Score = 37.5 bits (83), Expect = 0.33
Identities = 15/24 (62%), Positives = 21/24 (87%)
Frame = +2
Query: 164 APGKVILHGEHSVVYGKTAIAVSL 235
APGK+IL GEHSV+YG A+A+++
Sbjct: 12 APGKLILSGEHSVLYGAPALAMAI 35
>UniRef50_A5EVP5 Cluster: GHMP kinase family protein; n=1;
Dichelobacter nodosus VCS1703A|Rep: GHMP kinase family
protein - Dichelobacter nodosus (strain VCS1703A)
Length = 303
Score = 37.5 bits (83), Expect = 0.33
Identities = 20/60 (33%), Positives = 32/60 (53%)
Frame = +2
Query: 149 TVSVSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPAVHIHLPCVDLQET 328
T+ SA G V++ GEH+VVYG+ AI ++ R + + N + + IH D + T
Sbjct: 2 TIETSASGSVMICGEHAVVYGQPAIVAAIAQRIRVRLTPRN---DDKITIHSALGDYEST 58
>UniRef50_A5EUV5 Cluster: GHMP kinase family protein; n=1;
Dichelobacter nodosus VCS1703A|Rep: GHMP kinase family
protein - Dichelobacter nodosus (strain VCS1703A)
Length = 352
Score = 37.5 bits (83), Expect = 0.33
Identities = 16/24 (66%), Positives = 20/24 (83%)
Frame = +2
Query: 164 APGKVILHGEHSVVYGKTAIAVSL 235
APGK+IL GEH+VVYG AI V++
Sbjct: 8 APGKLILSGEHAVVYGAPAIVVAV 31
>UniRef50_Q6LXL5 Cluster: Mevalonate kinase; n=5; Methanococcus|Rep:
Mevalonate kinase - Methanococcus maripaludis
Length = 317
Score = 37.5 bits (83), Expect = 0.33
Identities = 26/76 (34%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Frame = +2
Query: 155 SVSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPAVHIHLPCVDLQETIP 334
++ P K+IL GEH+VV G AI+++L L+++ I+E + + I L VDL E
Sbjct: 3 TIKTPSKIILFGEHAVVDGYPAISMALDLKTTGEIEE----NFDTISIDL--VDLNEIFE 56
Query: 335 LEP-TVKSLFHPKLAP 379
+ P +K+L +P
Sbjct: 57 ITPELIKNLEISNFSP 72
>UniRef50_Q22LZ8 Cluster: ATPase, AAA family protein; n=1;
Tetrahymena thermophila SB210|Rep: ATPase, AAA family
protein - Tetrahymena thermophila SB210
Length = 741
Score = 37.1 bits (82), Expect = 0.44
Identities = 23/72 (31%), Positives = 40/72 (55%), Gaps = 1/72 (1%)
Frame = +2
Query: 65 LYLA*ALVNFACAYY-IKRTMLTAVDNLFTVSVSAPGKVILHGEHSVVYGKTAIAVSLGL 241
+Y + L+N+ AY I + M+ ++D + T S +++ G S+ GKTAIA + L
Sbjct: 502 VYKSNKLINYGEAYERISKQMIQSIDYVKTSENSLIHSILIEG--SIGTGKTAIAAAFAL 559
Query: 242 RSSIVIKEVNTP 277
+S I ++ TP
Sbjct: 560 KSDITYVKILTP 571
>UniRef50_A0E671 Cluster: Chromosome undetermined scaffold_8, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_8,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 288
Score = 37.1 bits (82), Expect = 0.44
Identities = 16/34 (47%), Positives = 23/34 (67%)
Frame = +2
Query: 158 VSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVI 259
V AP K+I+ GEHSVVYG A+ ++ ++I I
Sbjct: 3 VRAPAKIIISGEHSVVYGHKALCAAINKYTTIKI 36
>UniRef50_Q7QVN5 Cluster: GLP_305_18405_19430; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_305_18405_19430 - Giardia lamblia
ATCC 50803
Length = 341
Score = 36.3 bits (80), Expect = 0.77
Identities = 18/31 (58%), Positives = 21/31 (67%)
Frame = +2
Query: 158 VSAPGKVILHGEHSVVYGKTAIAVSLGLRSS 250
V P K IL GEHSVVYG IA++L L +S
Sbjct: 13 VRTPLKAILSGEHSVVYGHPCIAMALDLYTS 43
>UniRef50_Q38X71 Cluster: Mevalonate kinase; n=1; Lactobacillus
sakei subsp. sakei 23K|Rep: Mevalonate kinase -
Lactobacillus sakei subsp. sakei (strain 23K)
Length = 315
Score = 35.9 bits (79), Expect = 1.0
Identities = 23/81 (28%), Positives = 42/81 (51%), Gaps = 1/81 (1%)
Frame = +2
Query: 173 KVILHGEHSVVYGKTAIAVSL-GLRSSIVIKEVNTPHEPAVHIHLPCVDLQETIPLEPTV 349
K+IL GEH+VVYG+ AIA+ + +++++ + T EP ++ L + I +
Sbjct: 11 KIILIGEHAVVYGQPAIALPIFAVQTTVRVTAQPTLSEPLINSPYYSGLLSQAIGQMQGI 70
Query: 350 KSLFHPKLAPGDNRQILLEIT 412
+ L D++Q E+T
Sbjct: 71 RRLIEQLWQQLDDQQTAFELT 91
>UniRef50_Q03FN7 Cluster: Mevalonate kinase; n=1; Pediococcus
pentosaceus ATCC 25745|Rep: Mevalonate kinase -
Pediococcus pentosaceus (strain ATCC 25745 / 183-1w)
Length = 306
Score = 35.9 bits (79), Expect = 1.0
Identities = 17/38 (44%), Positives = 28/38 (73%), Gaps = 1/38 (2%)
Frame = +2
Query: 161 SAPGKVILHGEHSVVYGKTAIAVSL-GLRSSIVIKEVN 271
S+ K+IL GEHSVVYG+ AIA+ + +++++ I+ N
Sbjct: 7 SSNSKIILIGEHSVVYGQPAIALPIRNVKTTVKIQPTN 44
>UniRef50_A6G138 Cluster: Mevalonate kinase; n=1; Plesiocystis
pacifica SIR-1|Rep: Mevalonate kinase - Plesiocystis
pacifica SIR-1
Length = 320
Score = 35.9 bits (79), Expect = 1.0
Identities = 22/52 (42%), Positives = 28/52 (53%)
Frame = +2
Query: 164 APGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPAVHIHLPCVDL 319
A GK+IL GEHSVVYG A+A L R I+ A+ + +P DL
Sbjct: 11 ACGKIILLGEHSVVYGHPALAAGLS-RGLILRARPLDGRGGAMELSIPAWDL 61
>UniRef50_Q6C026 Cluster: Similarity; n=1; Yarrowia lipolytica|Rep:
Similarity - Yarrowia lipolytica (Candida lipolytica)
Length = 273
Score = 35.9 bits (79), Expect = 1.0
Identities = 27/104 (25%), Positives = 51/104 (49%), Gaps = 6/104 (5%)
Frame = +2
Query: 179 ILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPAVHIHLPCVDLQET-IPLEPTVKS 355
+L G+ ++Y K V + ++ ++ P ++ +H L++T +P+E +K
Sbjct: 110 LLGGKALLLYRKQKNQVLPWVELKRLVHTLDKPVLRSIAVHKELAKLEDTDLPIEYRIKM 169
Query: 356 LFH--PKLAP---GDNRQILLEITPQNRP*LSLAKGGGIPAFDQ 472
+ H P+L P GD ++ I P+ + A GGI +FDQ
Sbjct: 170 IRHWEPQLDPSPLGDRVVEVIRIIPEKEADIMKAVEGGISSFDQ 213
>UniRef50_Q83DT4 Cluster: Phosphomevalonate kinase, putative; n=2;
Coxiella burnetii|Rep: Phosphomevalonate kinase,
putative - Coxiella burnetii
Length = 313
Score = 35.5 bits (78), Expect = 1.3
Identities = 26/88 (29%), Positives = 42/88 (47%), Gaps = 4/88 (4%)
Frame = +2
Query: 164 APGKVILHGEHSVVYGKTAIAVSLGLRSSIVIK----EVNTPHEPAVHIHLPCVDLQETI 331
APG ++L GE++V+ GKTAI ++ SI + E P + L C ++ +
Sbjct: 7 APGSLMLLGEYAVLQGKTAIVAAIDKFISISLSPRHDEKINIDSPLGKLTLDCQSIKLSP 66
Query: 332 PLEPTVKSLFHPKLAPGDNRQILLEITP 415
P E + +L KL G + I + P
Sbjct: 67 PFEFVLAALASKKLPSGCDINIQSTLPP 94
>UniRef50_A6GIJ2 Cluster: Putative uncharacterized protein; n=1;
Plesiocystis pacifica SIR-1|Rep: Putative
uncharacterized protein - Plesiocystis pacifica SIR-1
Length = 88
Score = 35.5 bits (78), Expect = 1.3
Identities = 18/54 (33%), Positives = 29/54 (53%)
Frame = +3
Query: 537 SGIFGSTYLPVKSMDISMGSELTIGAGTGSSASFAVCLAGALIQLLKLKSLRGI 698
+ + G TYL KS + G+ GA TG+ A+ AV L A + +L + + G+
Sbjct: 10 TAVGGGTYLYAKSKQATTGTAAVAGAATGAGAAGAVLLVQAALPILIVAGIIGL 63
>UniRef50_A2U564 Cluster: Mevalonate kinase; n=1; Bacillus coagulans
36D1|Rep: Mevalonate kinase - Bacillus coagulans 36D1
Length = 314
Score = 35.5 bits (78), Expect = 1.3
Identities = 16/27 (59%), Positives = 22/27 (81%)
Frame = +2
Query: 149 TVSVSAPGKVILHGEHSVVYGKTAIAV 229
T + +A GK+IL GEH+VVYG+ AIA+
Sbjct: 8 TATGTAHGKLILAGEHAVVYGQPAIAL 34
>UniRef50_Q9FD69 Cluster: Mevalonate kinase; n=4; Enterococcus|Rep:
Mevalonate kinase - Enterococcus faecalis (Streptococcus
faecalis)
Length = 314
Score = 34.7 bits (76), Expect = 2.4
Identities = 15/21 (71%), Positives = 18/21 (85%)
Frame = +2
Query: 164 APGKVILHGEHSVVYGKTAIA 226
A GK+IL GEH+VVYG+ AIA
Sbjct: 11 ATGKIILMGEHAVVYGEPAIA 31
>UniRef50_Q2BIJ9 Cluster: GHMP kinase; n=1; Neptuniibacter
caesariensis|Rep: GHMP kinase - Neptuniibacter
caesariensis
Length = 309
Score = 34.7 bits (76), Expect = 2.4
Identities = 12/29 (41%), Positives = 22/29 (75%)
Frame = +2
Query: 149 TVSVSAPGKVILHGEHSVVYGKTAIAVSL 235
T+ V PG ++L GEH+V++G+ A+A ++
Sbjct: 3 TIKVKVPGSIMLMGEHAVLFGEKALACAV 31
>UniRef50_Q2GZQ7 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 460
Score = 34.7 bits (76), Expect = 2.4
Identities = 25/73 (34%), Positives = 39/73 (53%), Gaps = 1/73 (1%)
Frame = +2
Query: 149 TVSVSAPGKVILHGEHSVVYGK-TAIAVSLGLRSSIVIKEVNTPHEPAVHIHLPCVDLQE 325
TV VSAPGKV+L G + V+ K T + L R ++ +E++T + +HL + +Q
Sbjct: 12 TVVVSAPGKVLLAGGYIVLDRKHTGLVFGLSARIHVLAQEIHT----SAGVHLREIVVQS 67
Query: 326 TIPLEPTVKSLFH 364
L T K +H
Sbjct: 68 PQFLNATWKYGYH 80
>UniRef50_Q97UL6 Cluster: (Phospho) mevalonate kinase, putative;
n=4; Sulfolobaceae|Rep: (Phospho) mevalonate kinase,
putative - Sulfolobus solfataricus
Length = 323
Score = 34.7 bits (76), Expect = 2.4
Identities = 14/39 (35%), Positives = 26/39 (66%)
Frame = +2
Query: 152 VSVSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEV 268
+ VSAPGK++ G +SVV+G + +++ R S ++E+
Sbjct: 2 IKVSAPGKILWIGSYSVVFGGISHVIAVNKRVSCSLREI 40
>UniRef50_A3HYY0 Cluster: Galactokinase; n=1; Algoriphagus sp.
PR1|Rep: Galactokinase - Algoriphagus sp. PR1
Length = 382
Score = 34.3 bits (75), Expect = 3.1
Identities = 16/49 (32%), Positives = 29/49 (59%), Gaps = 1/49 (2%)
Frame = +3
Query: 564 PVKSMDISMGSELTIGAGTGSSASFAVCLAGALIQLLKLK-SLRGISMH 707
PVK DI G ++ +G+G SSA+ +V + A+ + K S + I+++
Sbjct: 103 PVKGFDIVFGGDIPVGSGLSSSAALSVAIGTAISAVFDFKISKKSIAIY 151
>UniRef50_A3DL21 Cluster: Mevalonate kinase; n=1; Staphylothermus
marinus F1|Rep: Mevalonate kinase - Staphylothermus
marinus (strain ATCC 43588 / DSM 3639 / F1)
Length = 324
Score = 34.3 bits (75), Expect = 3.1
Identities = 17/38 (44%), Positives = 23/38 (60%)
Frame = +2
Query: 161 SAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNT 274
+AP KVIL GEH VV K AI ++ L + I E+ +
Sbjct: 5 AAPAKVILFGEHFVVKDKPAIVTAVNLYAKTCITELES 42
>UniRef50_Q6ALT2 Cluster: Putative uncharacterized protein; n=1;
Desulfotalea psychrophila|Rep: Putative uncharacterized
protein - Desulfotalea psychrophila
Length = 938
Score = 33.9 bits (74), Expect = 4.1
Identities = 14/34 (41%), Positives = 22/34 (64%)
Frame = +2
Query: 350 KSLFHPKLAPGDNRQILLEITPQNRP*LSLAKGG 451
K F +LAPGD +++L++ PQNR + +GG
Sbjct: 897 KDTFKIELAPGDKKELLIKALPQNRTVQMIEQGG 930
>UniRef50_A5VK03 Cluster: Mevalonate kinase; n=2; Lactobacillus
reuteri|Rep: Mevalonate kinase - Lactobacillus reuteri
F275
Length = 316
Score = 33.9 bits (74), Expect = 4.1
Identities = 15/21 (71%), Positives = 18/21 (85%)
Frame = +2
Query: 173 KVILHGEHSVVYGKTAIAVSL 235
K+IL GEHSVVYG+ AIA+ L
Sbjct: 13 KIILMGEHSVVYGQPAIALPL 33
>UniRef50_A4VT18 Cluster: Mevalonate kinase; n=4; Streptococcus|Rep:
Mevalonate kinase - Streptococcus suis (strain 05ZYH33)
Length = 317
Score = 33.9 bits (74), Expect = 4.1
Identities = 15/22 (68%), Positives = 18/22 (81%)
Frame = +2
Query: 164 APGKVILHGEHSVVYGKTAIAV 229
A GK+IL GEH+VVYG AIA+
Sbjct: 13 ANGKIILMGEHAVVYGHPAIAM 34
>UniRef50_Q8F618 Cluster: Putative uncharacterized protein; n=2;
Leptospira interrogans|Rep: Putative uncharacterized
protein - Leptospira interrogans
Length = 77
Score = 33.5 bits (73), Expect = 5.4
Identities = 19/39 (48%), Positives = 25/39 (64%), Gaps = 1/39 (2%)
Frame = +3
Query: 426 HDYHLRRVEEYLHLIKPN-FDSLPNNQKNSLRSFLYVFS 539
+DYHLR +E +L +K N F S + SL+SFLYV S
Sbjct: 2 YDYHLRVLERFLKNLKGNDFCSFYKLFRFSLQSFLYVMS 40
>UniRef50_Q83DT3 Cluster: Mevalonate kinase, putative; n=3; Coxiella
burnetii|Rep: Mevalonate kinase, putative - Coxiella
burnetii
Length = 340
Score = 33.5 bits (73), Expect = 5.4
Identities = 13/23 (56%), Positives = 19/23 (82%)
Frame = +2
Query: 167 PGKVILHGEHSVVYGKTAIAVSL 235
P K+IL GEH+VVYG A++V++
Sbjct: 11 PAKLILSGEHAVVYGHPALSVAI 33
>UniRef50_Q8H912 Cluster: Putative zinc knuckle domain containing
protein; n=3; Oryza sativa (japonica
cultivar-group)|Rep: Putative zinc knuckle domain
containing protein - Oryza sativa subsp. japonica (Rice)
Length = 910
Score = 33.5 bits (73), Expect = 5.4
Identities = 21/56 (37%), Positives = 26/56 (46%), Gaps = 2/56 (3%)
Frame = +1
Query: 199 GRVRKNCDRCQPRPKELHSDKGS--KHSTRTSSPHTFAVRGSTGDHSIGADSQKSV 360
GR R + D CQ R + HS + S S RT SP + RG G G + K V
Sbjct: 575 GRQRAHGDGCQGRSRTRHSSRCSCRCRSRRTRSPSSLTPRGQDGTGDAGGATTKVV 630
>UniRef50_Q60ED2 Cluster: Putative uncharacterized protein
OSJNBa0002D18.17; n=5; Oryza sativa|Rep: Putative
uncharacterized protein OSJNBa0002D18.17 - Oryza sativa
subsp. japonica (Rice)
Length = 911
Score = 33.5 bits (73), Expect = 5.4
Identities = 13/33 (39%), Positives = 20/33 (60%)
Frame = -3
Query: 338 PMEWSPVDPRTANVCGLLVRVECLLPLSLWSSL 240
P+E V + +N CG LVR CL+ + LW ++
Sbjct: 131 PVEPPIVQSKFSNTCGTLVRTHCLINVKLWETV 163
>UniRef50_Q8SQK4 Cluster: MEVALONATE KINASE; n=1; Encephalitozoon
cuniculi|Rep: MEVALONATE KINASE - Encephalitozoon
cuniculi
Length = 276
Score = 33.5 bits (73), Expect = 5.4
Identities = 18/54 (33%), Positives = 29/54 (53%)
Frame = +2
Query: 164 APGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPAVHIHLPCVDLQE 325
+P KVIL GEH V+ G +AV++ + + +K + + + CVDL E
Sbjct: 7 SPLKVILFGEHGVLSGGRCLAVAIDVYGYLAMKSSSINKAIIIDTNGNCVDLIE 60
>UniRef50_UPI0000DB7B87 Cluster: PREDICTED: similar to CG5127-PA
isoform 2; n=1; Apis mellifera|Rep: PREDICTED: similar
to CG5127-PA isoform 2 - Apis mellifera
Length = 554
Score = 33.1 bits (72), Expect = 7.2
Identities = 13/33 (39%), Positives = 20/33 (60%)
Frame = -1
Query: 478 LGLIKCRYSSTLRK**SWSILWGNLQENLPVIP 380
+GL+KCR + L K +WS W N + L ++P
Sbjct: 409 IGLLKCRLENILHKLPNWSSEWNNNAQKLKLLP 441
>UniRef50_Q08UJ8 Cluster: Mevalonate kinase; n=2;
Cystobacterineae|Rep: Mevalonate kinase - Stigmatella
aurantiaca DW4/3-1
Length = 310
Score = 33.1 bits (72), Expect = 7.2
Identities = 15/19 (78%), Positives = 16/19 (84%)
Frame = +2
Query: 170 GKVILHGEHSVVYGKTAIA 226
GKVIL GEHSVVYG A+A
Sbjct: 14 GKVILLGEHSVVYGHPALA 32
>UniRef50_Q031R4 Cluster: Mevalonate kinase; n=3; Lactococcus
lactis|Rep: Mevalonate kinase - Lactococcus lactis
subsp. cremoris (strain SK11)
Length = 310
Score = 33.1 bits (72), Expect = 7.2
Identities = 16/31 (51%), Positives = 22/31 (70%)
Frame = +2
Query: 164 APGKVILHGEHSVVYGKTAIAVSLGLRSSIV 256
A K+IL GEHSVVYG+ AIA+ + + + V
Sbjct: 11 AHSKLILIGEHSVVYGQPAIALPVTILKTTV 41
>UniRef50_A4AD88 Cluster: Galactokinase; n=1; Congregibacter
litoralis KT71|Rep: Galactokinase - Congregibacter
litoralis KT71
Length = 393
Score = 33.1 bits (72), Expect = 7.2
Identities = 18/42 (42%), Positives = 25/42 (59%)
Frame = +3
Query: 567 VKSMDISMGSELTIGAGTGSSASFAVCLAGALIQLLKLKSLR 692
V MD+ +G L +GAG SSAS +C A LI+ + +LR
Sbjct: 124 VPPMDLVIGGNLPLGAGLSSSASLELCFA-TLIETVTGHALR 164
>UniRef50_A1VCN1 Cluster: Small multidrug resistance protein; n=4;
Bacteria|Rep: Small multidrug resistance protein -
Desulfovibrio vulgaris subsp. vulgaris (strain DP4)
Length = 109
Score = 33.1 bits (72), Expect = 7.2
Identities = 17/56 (30%), Positives = 31/56 (55%)
Frame = +3
Query: 522 FLYVFSGIFGSTYLPVKSMDISMGSELTIGAGTGSSASFAVCLAGALIQLLKLKSL 689
FL+ ++G + + VK MD+S+ + G GT + A +C+ G ++K+ SL
Sbjct: 38 FLFYGLALWGLSVV-VKKMDVSIAYAVWSGVGTATVAMIGICIFGERATVVKICSL 92
>UniRef50_Q7XJS3 Cluster: At2g17440 protein; n=3; Brassicaceae|Rep:
At2g17440 protein - Arabidopsis thaliana (Mouse-ear
cress)
Length = 526
Score = 33.1 bits (72), Expect = 7.2
Identities = 15/27 (55%), Positives = 18/27 (66%)
Frame = -1
Query: 667 CINAPARQTAKDAELPVPAPMVSSDPI 587
CI +P TA +PVPAP+VSSD I
Sbjct: 109 CIASPNSTTALPRSVPVPAPVVSSDEI 135
>UniRef50_Q8ZTT2 Cluster: Mevalonate kinase; n=4; Pyrobaculum|Rep:
Mevalonate kinase - Pyrobaculum aerophilum
Length = 314
Score = 33.1 bits (72), Expect = 7.2
Identities = 14/28 (50%), Positives = 19/28 (67%)
Frame = +2
Query: 152 VSVSAPGKVILHGEHSVVYGKTAIAVSL 235
V + P V L GEH+VVYGK AI+ ++
Sbjct: 2 VKIFVPAAVKLFGEHAVVYGKPAISAAI 29
>UniRef50_Q1WU40 Cluster: Mevalonate kinase; n=1; Lactobacillus
salivarius subsp. salivarius UCC118|Rep: Mevalonate
kinase - Lactobacillus salivarius subsp. salivarius
(strain UCC118)
Length = 314
Score = 32.7 bits (71), Expect = 9.5
Identities = 15/25 (60%), Positives = 19/25 (76%)
Frame = +2
Query: 161 SAPGKVILHGEHSVVYGKTAIAVSL 235
S+ K+IL GEH+VVYG AIA+ L
Sbjct: 10 SSHAKIILIGEHAVVYGHPAIALPL 34
>UniRef50_Q9VR26 Cluster: CG3294-PA, isoform A; n=4; Sophophora|Rep:
CG3294-PA, isoform A - Drosophila melanogaster (Fruit
fly)
Length = 446
Score = 32.7 bits (71), Expect = 9.5
Identities = 16/41 (39%), Positives = 17/41 (41%)
Frame = +1
Query: 208 RKNCDRCQPRPKELHSDKGSKHSTRTSSPHTFAVRGSTGDH 330
R DR R K HS GS H R S H +T DH
Sbjct: 400 RSRSDRSSVRSKREHSSSGSSHDDRRSKRHHHHHNSTTPDH 440
>UniRef50_Q8TQ19 Cluster: Putative uncharacterized protein; n=2;
Methanosarcina|Rep: Putative uncharacterized protein -
Methanosarcina acetivorans
Length = 225
Score = 32.7 bits (71), Expect = 9.5
Identities = 19/57 (33%), Positives = 29/57 (50%)
Frame = +3
Query: 468 IKPNFDSLPNNQKNSLRSFLYVFSGIFGSTYLPVKSMDISMGSELTIGAGTGSSASF 638
I+ FD++ R F+ F +G+T + V S+ S L IGAGTG ++F
Sbjct: 4 IQQKFDAISKKYDEQRRKFIPCFDDFYGAT-VSVASVYTENPSILDIGAGTGLLSAF 59
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 797,078,074
Number of Sequences: 1657284
Number of extensions: 17987909
Number of successful extensions: 51382
Number of sequences better than 10.0: 86
Number of HSP's better than 10.0 without gapping: 48965
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 51363
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 59090914597
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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