Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P06_F_I19
(727 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AB209722-1|BAD92959.1| 421|Homo sapiens mevalonate kinase varia... 55 2e-07
M88468-1|AAB59362.1| 396|Homo sapiens mevalonate kinase protein. 54 4e-07
BC016140-1|AAH16140.1| 396|Homo sapiens MVK protein protein. 54 4e-07
AF217536-1|AAF82406.1| 113|Homo sapiens truncated mevalonate ki... 54 4e-07
AF217535-1|AAF82407.1| 396|Homo sapiens mevalonate kinase protein. 54 4e-07
Z34278-1|CAA84032.1| 279|Homo sapiens mucin protein. 31 5.6
AJ417790-1|CAD10507.1| 1791|Homo sapiens voltage-gated sodium ch... 30 7.3
AF188679-1|AAF17480.1| 1791|Homo sapiens voltage-gated sodium ch... 30 7.3
AF109737-1|AAF24976.1| 1791|Homo sapiens voltage-gated sodium ch... 30 7.3
>AB209722-1|BAD92959.1| 421|Homo sapiens mevalonate kinase variant
protein.
Length = 421
Score = 55.2 bits (127), Expect = 2e-07
Identities = 29/56 (51%), Positives = 41/56 (73%), Gaps = 1/56 (1%)
Frame = +2
Query: 158 VSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPA-VHIHLPCVDLQ 322
VSAPGKVILHGEH+VV+GK A+AVSL LR+ + ++ PH V ++LP + ++
Sbjct: 33 VSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQ----PHSNGKVDLNLPNIGIK 84
Score = 43.6 bits (98), Expect = 7e-04
Identities = 24/61 (39%), Positives = 38/61 (62%)
Frame = +3
Query: 483 DSLPNNQKNSLRSFLYVFSGIFGSTYLPVKSMDISMGSELTIGAGTGSSASFAVCLAGAL 662
D ++ ++ +FLY++ I + S+DI + SEL GAG GSSA+++VCLA AL
Sbjct: 124 DDCAVTERLAVLAFLYLYLSICRKQRA-LPSLDIVVWSELPPGAGLGSSAAYSVCLAAAL 182
Query: 663 I 665
+
Sbjct: 183 L 183
>M88468-1|AAB59362.1| 396|Homo sapiens mevalonate kinase protein.
Length = 396
Score = 54.4 bits (125), Expect = 4e-07
Identities = 29/56 (51%), Positives = 40/56 (71%), Gaps = 1/56 (1%)
Frame = +2
Query: 158 VSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPA-VHIHLPCVDLQ 322
VSAPGKVILHGEH+VV+GK A+AVSL LR+ + ++ PH V + LP + ++
Sbjct: 8 VSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQ----PHSNGKVDLSLPNIGIK 59
Score = 43.6 bits (98), Expect = 7e-04
Identities = 24/61 (39%), Positives = 38/61 (62%)
Frame = +3
Query: 483 DSLPNNQKNSLRSFLYVFSGIFGSTYLPVKSMDISMGSELTIGAGTGSSASFAVCLAGAL 662
D ++ ++ +FLY++ I + S+DI + SEL GAG GSSA+++VCLA AL
Sbjct: 99 DDCAVTERLAVLAFLYLYLSICRKQRA-LPSLDIVVWSELPPGAGLGSSAAYSVCLAAAL 157
Query: 663 I 665
+
Sbjct: 158 L 158
>BC016140-1|AAH16140.1| 396|Homo sapiens MVK protein protein.
Length = 396
Score = 54.4 bits (125), Expect = 4e-07
Identities = 29/56 (51%), Positives = 40/56 (71%), Gaps = 1/56 (1%)
Frame = +2
Query: 158 VSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPA-VHIHLPCVDLQ 322
VSAPGKVILHGEH+VV+GK A+AVSL LR+ + ++ PH V + LP + ++
Sbjct: 8 VSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQ----PHSNGKVDLSLPNIGIK 59
Score = 43.6 bits (98), Expect = 7e-04
Identities = 24/61 (39%), Positives = 38/61 (62%)
Frame = +3
Query: 483 DSLPNNQKNSLRSFLYVFSGIFGSTYLPVKSMDISMGSELTIGAGTGSSASFAVCLAGAL 662
D ++ ++ +FLY++ I + S+DI + SEL GAG GSSA+++VCLA AL
Sbjct: 99 DDCAVTERLAVLAFLYLYLSICRKQRA-LPSLDIVVWSELPPGAGLGSSAAYSVCLAAAL 157
Query: 663 I 665
+
Sbjct: 158 L 158
>AF217536-1|AAF82406.1| 113|Homo sapiens truncated mevalonate
kinase protein.
Length = 113
Score = 54.4 bits (125), Expect = 4e-07
Identities = 29/56 (51%), Positives = 40/56 (71%), Gaps = 1/56 (1%)
Frame = +2
Query: 158 VSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPA-VHIHLPCVDLQ 322
VSAPGKVILHGEH+VV+GK A+AVSL LR+ + ++ PH V + LP + ++
Sbjct: 4 VSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQ----PHSNGKVDLSLPNIGIK 55
>AF217535-1|AAF82407.1| 396|Homo sapiens mevalonate kinase protein.
Length = 396
Score = 54.4 bits (125), Expect = 4e-07
Identities = 29/56 (51%), Positives = 40/56 (71%), Gaps = 1/56 (1%)
Frame = +2
Query: 158 VSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPA-VHIHLPCVDLQ 322
VSAPGKVILHGEH+VV+GK A+AVSL LR+ + ++ PH V + LP + ++
Sbjct: 8 VSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQ----PHSNGKVDLSLPNIGIK 59
Score = 43.6 bits (98), Expect = 7e-04
Identities = 24/61 (39%), Positives = 38/61 (62%)
Frame = +3
Query: 483 DSLPNNQKNSLRSFLYVFSGIFGSTYLPVKSMDISMGSELTIGAGTGSSASFAVCLAGAL 662
D ++ ++ +FLY++ I + S+DI + SEL GAG GSSA+++VCLA AL
Sbjct: 99 DDCAVTERLAVLAFLYLYLSICRKQRA-LPSLDIVVWSELPPGAGLGSSAAYSVCLAAAL 157
Query: 663 I 665
+
Sbjct: 158 L 158
>Z34278-1|CAA84032.1| 279|Homo sapiens mucin protein.
Length = 279
Score = 30.7 bits (66), Expect = 5.6
Identities = 21/69 (30%), Positives = 27/69 (39%)
Frame = +1
Query: 232 PRPKELHSDKGSKHSTRTSSPHTFAVRGSTGDHSIGADSQKSVPS*TGTRG*PANSLGDY 411
PRP S S ++ TS+P T ST + GA + S T T P
Sbjct: 56 PRPVPTTSTTSSPTTSTTSAPTTSTTSASTTSTTSGAGTTPSPVPTTSTTSAPTTRTTSA 115
Query: 412 PTKSTMTIT 438
P ST + T
Sbjct: 116 PISSTTSAT 124
>AJ417790-1|CAD10507.1| 1791|Homo sapiens voltage-gated sodium channel
protein.
Length = 1791
Score = 30.3 bits (65), Expect = 7.3
Identities = 18/72 (25%), Positives = 26/72 (36%)
Frame = -2
Query: 456 IPPPFASDSHGRFCGVISKRICRLSPGASLGWNRLLTVGSNGMVSCRSTHGKCMWTAGSC 277
+ P D F S +C S GW+ LL+ SC S+ C +
Sbjct: 1522 VNPESGIDDIFNFKTFASSMLCLFQISTSAGWDSLLSPMLRSKESCNSSSENCHLPGIAT 1581
Query: 276 GVFTSFITMELL 241
F S+I + L
Sbjct: 1582 SYFVSYIIISFL 1593
>AF188679-1|AAF17480.1| 1791|Homo sapiens voltage-gated sodium channel
type XI alpha subunit protein.
Length = 1791
Score = 30.3 bits (65), Expect = 7.3
Identities = 18/72 (25%), Positives = 26/72 (36%)
Frame = -2
Query: 456 IPPPFASDSHGRFCGVISKRICRLSPGASLGWNRLLTVGSNGMVSCRSTHGKCMWTAGSC 277
+ P D F S +C S GW+ LL+ SC S+ C +
Sbjct: 1522 VNPESGIDDIFNFKTFASSMLCLFQISTSAGWDSLLSPMLRSKESCNSSSENCHLPGIAT 1581
Query: 276 GVFTSFITMELL 241
F S+I + L
Sbjct: 1582 SYFVSYIIISFL 1593
>AF109737-1|AAF24976.1| 1791|Homo sapiens voltage-gated sodium channel
alpha subunit SCN12A protein.
Length = 1791
Score = 30.3 bits (65), Expect = 7.3
Identities = 18/72 (25%), Positives = 26/72 (36%)
Frame = -2
Query: 456 IPPPFASDSHGRFCGVISKRICRLSPGASLGWNRLLTVGSNGMVSCRSTHGKCMWTAGSC 277
+ P D F S +C S GW+ LL+ SC S+ C +
Sbjct: 1522 VNPESGIDDIFNFKTFASSMLCLFQISTSAGWDSLLSPMLRSKESCNSSSENCHLPGIAT 1581
Query: 276 GVFTSFITMELL 241
F S+I + L
Sbjct: 1582 SYFVSYIIISFL 1593
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 117,529,841
Number of Sequences: 237096
Number of extensions: 2827900
Number of successful extensions: 6880
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 6453
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6880
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8567175942
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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