Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P06_F_F02
(796 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M24194-1|AAA59626.1| 317|Homo sapiens MHC B complex protein 12.... 419 e-117
CR541909-1|CAG46707.1| 317|Homo sapiens GNB2L1 protein. 419 e-117
CR456978-1|CAG33259.1| 317|Homo sapiens GNB2L1 protein. 419 e-117
BC032006-1|AAH32006.1| 317|Homo sapiens guanine nucleotide bind... 419 e-117
BC021993-1|AAH21993.1| 317|Homo sapiens guanine nucleotide bind... 419 e-117
BC019362-1|AAH19362.1| 317|Homo sapiens guanine nucleotide bind... 419 e-117
BC019093-1|AAH19093.1| 317|Homo sapiens guanine nucleotide bind... 419 e-117
BC017287-1|AAH17287.1| 317|Homo sapiens guanine nucleotide bind... 419 e-117
BC014788-1|AAH14788.1| 317|Homo sapiens guanine nucleotide bind... 419 e-117
BC014256-1|AAH14256.1| 317|Homo sapiens guanine nucleotide bind... 419 e-117
BC010119-1|AAH10119.1| 317|Homo sapiens guanine nucleotide bind... 419 e-117
BC000366-1|AAH00366.1| 317|Homo sapiens guanine nucleotide bind... 419 e-117
BC000214-1|AAH00214.1| 317|Homo sapiens guanine nucleotide bind... 419 e-117
AY159316-1|AAO21313.1| 347|Homo sapiens lung cancer oncogene 7 ... 419 e-117
AK222488-1|BAD96208.1| 317|Homo sapiens guanine nucleotide bind... 417 e-116
AY336089-1|AAR24619.1| 271|Homo sapiens proliferation-inducing ... 254 2e-67
EF011619-1|ABK41109.1| 478|Homo sapiens CDW9/WDR51B protein. 122 2e-27
BC026080-1|AAH26080.1| 478|Homo sapiens WD repeat domain 51B pr... 122 2e-27
AK074772-1|BAC11198.1| 478|Homo sapiens protein ( Homo sapiens ... 122 2e-27
CR457279-1|CAG33560.1| 330|Homo sapiens WDR5B protein. 112 1e-24
BC043494-1|AAH43494.1| 330|Homo sapiens WD repeat domain 5B pro... 112 1e-24
AK002149-1|BAA92110.1| 330|Homo sapiens protein ( Homo sapiens ... 112 1e-24
BX649632-1|CAI18774.1| 334|Homo sapiens WD repeat domain 5 prot... 108 2e-23
BC001635-1|AAH01635.1| 334|Homo sapiens WD repeat domain 5 prot... 108 2e-23
AK000552-1|BAA91248.1| 334|Homo sapiens protein ( Homo sapiens ... 108 2e-23
AJ011376-1|CAB66159.1| 362|Homo sapiens hypothetical protein pr... 108 2e-23
BC127949-1|AAI27950.1| 314|Homo sapiens WD repeat domain 38 pro... 106 8e-23
U72342-1|AAC51111.1| 410|Homo sapiens platelet activating facto... 105 1e-22
L13386-1|AAA02881.1| 410|Homo sapiens Miller-Dieker lissencepha... 105 1e-22
L13385-1|AAA02880.1| 410|Homo sapiens Miller-Dieker lissencepha... 105 1e-22
BC064638-1|AAH64638.1| 410|Homo sapiens platelet-activating fac... 105 1e-22
AF400434-1|AAK92483.1| 410|Homo sapiens platelet-activating fac... 105 1e-22
AF208837-1|AAL34972.1| 410|Homo sapiens Miller-Dieker lissencep... 105 1e-22
AL354928-6|CAI39637.1| 314|Homo sapiens WD repeat domain 38 pro... 105 2e-22
BC036377-1|AAH36377.1| 415|Homo sapiens WD repeat domain 69 pro... 103 7e-22
AK098821-1|BAC05425.1| 415|Homo sapiens protein ( Homo sapiens ... 103 7e-22
AK097409-1|BAC05039.1| 415|Homo sapiens protein ( Homo sapiens ... 103 7e-22
AC073065-2|AAX93215.1| 415|Homo sapiens unknown protein. 103 7e-22
CR456762-1|CAG33043.1| 655|Homo sapiens KATNB1 protein. 101 2e-21
BT007022-1|AAP35668.1| 655|Homo sapiens katanin p80 (WD40-conta... 101 2e-21
BC001353-1|AAH01353.1| 655|Homo sapiens katanin p80 (WD repeat ... 101 2e-21
AF208838-1|AAL34973.1| 410|Homo sapiens Miller-Dieker lissencep... 100 7e-21
BC012075-1|AAH12075.1| 485|Homo sapiens notchless homolog 1 (Dr... 99 2e-20
BC002884-1|AAH02884.2| 484|Homo sapiens NLE1 protein protein. 99 2e-20
AK001320-1|BAA91621.1| 485|Homo sapiens protein ( Homo sapiens ... 99 2e-20
AB209111-1|BAD92348.1| 487|Homo sapiens Notchless gene homolog ... 99 2e-20
X95525-1|CAA64777.1| 799|Homo sapiens hTAFII100 protein. 98 3e-20
U80191-1|AAC51215.1| 800|Homo sapiens TFIID subunit TAFII100 pr... 98 3e-20
U75309-1|AAC50902.1| 801|Homo sapiens TBP-associated factor pro... 98 3e-20
BC052268-1|AAH52268.2| 800|Homo sapiens TAF5 RNA polymerase II,... 98 3e-20
AL591408-4|CAI16747.1| 800|Homo sapiens TAF5 RNA polymerase II,... 98 3e-20
AK223615-1|BAD97335.1| 803|Homo sapiens Transcription initiatio... 98 3e-20
AF090988-1|AAC69625.1| 357|Homo sapiens U5 snRNP-specific 40 kD... 98 3e-20
EF011621-1|ABK41111.1| 357|Homo sapiens CDW11/WDR57 protein. 97 5e-20
BC001494-1|AAH01494.1| 357|Homo sapiens WD repeat domain 57 (U5... 97 5e-20
AL451070-1|CAH71848.1| 357|Homo sapiens WD repeat domain 57 (U5... 97 5e-20
AF001687-1|AAB87640.1| 521|Homo sapiens U4/U6 snRNP 60 kDa prot... 97 5e-20
AF083383-1|AAC64084.1| 310|Homo sapiens 38kDa splicing factor p... 97 6e-20
L13387-1|AAA02882.1| 288|Homo sapiens Miller-Dieker lissencepha... 97 9e-20
AF052432-1|AAC09328.1| 655|Homo sapiens katanin p80 subunit pro... 97 9e-20
AK127882-1|BAC87175.1| 369|Homo sapiens protein ( Homo sapiens ... 96 1e-19
AK075289-1|BAC11525.1| 407|Homo sapiens protein ( Homo sapiens ... 95 2e-19
BC119693-1|AAI19694.1| 441|Homo sapiens WDR51A protein protein. 95 3e-19
BC119692-1|AAI19693.1| 407|Homo sapiens WD repeat domain 51A pr... 95 3e-19
BC110877-1|AAI10878.1| 359|Homo sapiens WDR51A protein protein. 95 3e-19
BC007417-1|AAH07417.2| 396|Homo sapiens WDR51A protein protein. 95 3e-19
U82756-1|AAC02261.1| 520|Homo sapiens WD splicing factor Hprp4p... 95 3e-19
CR457105-1|CAG33386.1| 521|Homo sapiens PRPF4 protein. 95 3e-19
BC007424-1|AAH07424.1| 521|Homo sapiens PRP4 pre-mRNA processin... 95 3e-19
BC001588-1|AAH01588.1| 522|Homo sapiens PRP4 pre-mRNA processin... 95 3e-19
AY572489-1|AAS78572.1| 521|Homo sapiens 60 kDa U4/U6 snRNP-spec... 95 3e-19
AL449305-8|CAI10969.1| 521|Homo sapiens PRP4 pre-mRNA processin... 95 3e-19
AL449305-7|CAI10968.1| 522|Homo sapiens PRP4 pre-mRNA processin... 95 3e-19
AL121990-7|CAI22015.1| 589|Homo sapiens TAF5-like RNA polymeras... 95 3e-19
AJ009770-1|CAA08816.1| 260|Homo sapiens putative transcription ... 95 3e-19
AF069736-1|AAC39906.1| 589|Homo sapiens PCAF associated factor ... 95 3e-19
AF016369-1|AAC51925.1| 522|Homo sapiens U4/U6 small nuclear rib... 95 3e-19
AB209797-1|BAD93034.1| 537|Homo sapiens PRPF4 protein variant p... 95 3e-19
BC025379-1|AAH25379.1| 571|Homo sapiens SPAG16 protein protein. 90 7e-18
AF490390-1|AAM97147.1| 631|Homo sapiens sperm-associated WD rep... 90 7e-18
AF310672-1|AAM63956.1| 631|Homo sapiens PF20 variant 1a protein. 90 7e-18
AB053276-1|BAB69430.1| 348|Homo sapiens TUWD12 protein. 90 7e-18
AB053266-1|BAB69057.1| 348|Homo sapiens TUWD12 protein. 90 7e-18
BC106004-1|AAI06005.1| 514|Homo sapiens pleiotropic regulator 1... 90 1e-17
BC020786-1|AAH20786.1| 505|Homo sapiens PLRG1 protein protein. 90 1e-17
AF044333-1|AAD09407.1| 514|Homo sapiens pleiotropic regulator 1... 90 1e-17
X70476-1|CAA49900.1| 906|Homo sapiens subunit of coatomer compl... 87 5e-17
BC000326-1|AAH00326.1| 906|Homo sapiens coatomer protein comple... 87 5e-17
BC150255-1|AAI50256.1| 1237|Homo sapiens apoptotic peptidase act... 87 7e-17
BC117246-1|AAI17247.1| 707|Homo sapiens F-box and WD repeat dom... 87 7e-17
BC117244-1|AAI17245.1| 707|Homo sapiens F-box and WD repeat dom... 87 7e-17
BC037320-1|AAH37320.1| 621|Homo sapiens FBXW7 protein protein. 87 7e-17
AY049984-1|AAL07271.1| 707|Homo sapiens F-box protein CDC4 prot... 87 7e-17
AY033553-1|AAK57547.1| 627|Homo sapiens F-box protein FBW7 prot... 87 7e-17
AY008274-1|AAG16640.1| 589|Homo sapiens F-box protein SEL10 pro... 87 7e-17
AK223449-1|BAD97169.1| 627|Homo sapiens F-box protein FBW7 isof... 87 7e-17
AK001933-1|BAA91986.1| 553|Homo sapiens protein ( Homo sapiens ... 87 7e-17
AJ243048-1|CAB55588.1| 1248|Homo sapiens apoptotic protease acti... 87 7e-17
AJ243009-1|CAB55585.1| 1248|Homo sapiens apoptotic protease acti... 87 7e-17
AJ243006-1|CAB55582.1| 1205|Homo sapiens apoptotic protease acti... 87 7e-17
AJ243005-1|CAB55581.1| 1205|Homo sapiens apoptotic protease acti... 87 7e-17
AJ243004-1|CAB55580.1| 1205|Homo sapiens apoptotic protease acti... 87 7e-17
AJ243003-1|CAB55579.1| 1205|Homo sapiens apoptotic protease acti... 87 7e-17
AF411972-1|AAL06291.1| 627|Homo sapiens archipelago beta form p... 87 7e-17
AF411971-1|AAL06290.1| 707|Homo sapiens archipelago alpha form ... 87 7e-17
AF383178-1|AAK60269.1| 561|Homo sapiens F-box protein FBX30 pro... 87 7e-17
AF149794-1|AAD34016.1| 1248|Homo sapiens apoptotic protease acti... 87 7e-17
AF134397-1|AAD38344.1| 1237|Homo sapiens apoptotic protease acti... 87 7e-17
AF013263-1|AAC51678.1| 1194|Homo sapiens apoptotic protease acti... 87 7e-17
AB209725-1|BAD92962.1| 624|Homo sapiens F-box protein FBW7 isof... 87 7e-17
AB007873-1|BAA24843.2| 1237|Homo sapiens KIAA0413 protein. 87 7e-17
AJ243011-1|CAB55587.1| 1205|Homo sapiens protease activating fac... 87 9e-17
AJ243010-1|CAB55586.1| 1205|Homo sapiens apoptotic protease acti... 86 1e-16
BC023662-1|AAH23662.2| 475|Homo sapiens RRP9, small subunit (SS... 86 2e-16
BC010048-1|AAH10048.1| 475|Homo sapiens RRP9, small subunit (SS... 86 2e-16
BC009879-1|AAH09879.1| 475|Homo sapiens RRP9, small subunit (SS... 86 2e-16
BC001113-1|AAH01113.1| 475|Homo sapiens RRP9, small subunit (SS... 86 2e-16
AJ001340-1|CAA04687.1| 475|Homo sapiens U3 snoRNP associated 55... 86 2e-16
AJ243007-1|CAB55583.1| 1205|Homo sapiens apoptotic protease acti... 85 2e-16
AJ243107-1|CAB56462.1| 1171|Homo sapiens apoptotic protease acti... 84 5e-16
AJ243008-1|CAB55584.1| 1205|Homo sapiens apoptotic protease acti... 84 6e-16
EF560718-1|ABQ59028.1| 1205|Homo sapiens APAF1 protein protein. 83 1e-15
Y12781-1|CAA73319.1| 577|Homo sapiens transducin (beta) like 1 ... 80 1e-14
BC052304-1|AAH52304.1| 577|Homo sapiens transducin (beta)-like ... 80 1e-14
BC032708-1|AAH32708.1| 526|Homo sapiens TBL1X protein protein. 80 1e-14
AB209608-1|BAD92845.1| 540|Homo sapiens transducin beta-like 1X... 80 1e-14
BC130473-1|AAI30474.1| 522|Homo sapiens transducin (beta)-like ... 79 1e-14
BC130471-1|AAI30472.1| 522|Homo sapiens transducin (beta)-like ... 79 1e-14
BC113421-1|AAI13422.1| 514|Homo sapiens transducin (beta)-like ... 79 1e-14
AK022956-1|BAB14331.1| 514|Homo sapiens protein ( Homo sapiens ... 79 1e-14
AF332222-1|AAK13474.1| 522|Homo sapiens transducin beta-like 1 ... 79 1e-14
AF332221-1|AAK13473.1| 522|Homo sapiens transducin beta-like 1 ... 79 1e-14
AF332220-1|AAK13472.1| 522|Homo sapiens transducin beta-like 1 ... 79 1e-14
AF314544-1|AAK00301.1| 514|Homo sapiens nuclear receptor co-rep... 79 1e-14
AF268193-1|AAG44736.1| 514|Homo sapiens IRA1 protein. 79 1e-14
AB040882-1|BAA95973.2| 680|Homo sapiens KIAA1449 protein protein. 79 2e-14
Y14153-1|CAA74572.1| 569|Homo sapiens beta-transducin repeats c... 79 2e-14
BC027994-1|AAH27994.1| 605|Homo sapiens beta-transducin repeat ... 79 2e-14
BC026353-1|AAH26353.1| 677|Homo sapiens WD repeat domain 48 pro... 79 2e-14
AL627424-18|CAI41043.1| 569|Homo sapiens beta-transducin repeat... 79 2e-14
AL627424-17|CAI41042.1| 605|Homo sapiens beta-transducin repeat... 79 2e-14
AL445463-3|CAI12964.1| 569|Homo sapiens beta-transducin repeat ... 79 2e-14
AL445463-2|CAI12963.1| 605|Homo sapiens beta-transducin repeat ... 79 2e-14
AL133387-2|CAH70019.1| 569|Homo sapiens beta-transducin repeat ... 79 2e-14
AL133387-1|CAH70020.1| 605|Homo sapiens beta-transducin repeat ... 79 2e-14
AF468833-1|AAL78650.1| 677|Homo sapiens WD repeat endosomal pro... 79 2e-14
AF129530-1|AAF04464.1| 569|Homo sapiens F-box protein Fbw1A pro... 79 2e-14
AF101784-1|AAD08702.1| 605|Homo sapiens b-TRCP variant E3RS-Ika... 79 2e-14
BC031227-1|AAH31227.2| 452|Homo sapiens WDR88 protein protein. 78 3e-14
M36429-1|AAA63264.1| 340|Homo sapiens protein ( Human transduci... 78 4e-14
M16538-1|AAA35922.1| 340|Homo sapiens protein ( Human signal-tr... 78 4e-14
M16514-1|AAA03179.1| 340|Homo sapiens GNB2 protein. 78 4e-14
CR541729-1|CAG46530.1| 340|Homo sapiens GNB2 protein. 78 4e-14
BC107125-1|AAI07126.1| 248|Homo sapiens WDR86 protein protein. 78 4e-14
BC068003-1|AAH68003.1| 340|Homo sapiens guanine nucleotide bind... 78 4e-14
BC047921-1|AAH47921.1| 563|Homo sapiens WDR86 protein protein. 78 4e-14
BC032551-1|AAH32551.1| 795|Homo sapiens phospholipase A2-activa... 78 4e-14
BC012348-1|AAH12348.1| 340|Homo sapiens guanine nucleotide bind... 78 4e-14
BC010073-1|AAH10073.1| 340|Homo sapiens guanine nucleotide bind... 78 4e-14
BC000873-1|AAH00873.1| 340|Homo sapiens guanine nucleotide bind... 78 4e-14
AK002143-1|BAA92105.1| 544|Homo sapiens protein ( Homo sapiens ... 78 4e-14
AF501883-1|AAM15919.1| 340|Homo sapiens guanine nucleotide bind... 78 4e-14
AF300648-1|AAG18442.1| 340|Homo sapiens guanine nucleotide bind... 78 4e-14
AF053356-4|AAC78794.1| 340|Homo sapiens GNB2 protein. 78 4e-14
EF011613-1|ABK41103.1| 513|Homo sapiens CDW3/SMU1 protein. 77 6e-14
BC110654-1|AAI10655.1| 513|Homo sapiens smu-1 suppressor of mec... 77 6e-14
BC002876-1|AAH02876.1| 513|Homo sapiens smu-1 suppressor of mec... 77 6e-14
AL162590-6|CAI15554.1| 513|Homo sapiens smu-1 suppressor of mec... 77 6e-14
AK022782-1|BAB14243.1| 423|Homo sapiens protein ( Homo sapiens ... 77 6e-14
AK022781-1|BAB14242.1| 423|Homo sapiens protein ( Homo sapiens ... 77 6e-14
AK001667-1|BAA91822.1| 513|Homo sapiens protein ( Homo sapiens ... 77 6e-14
AF242546-1|AAF60355.1| 423|Homo sapiens YTM1 protein. 77 6e-14
X04526-2|CAA28207.1| 340|Homo sapiens protein ( Human liver mRN... 77 7e-14
M36430-1|AAA63265.1| 247|Homo sapiens protein ( Human transduci... 77 7e-14
EF011617-1|ABK41107.1| 423|Homo sapiens CDW7/WDR12 protein. 77 7e-14
CR456784-1|CAG33065.1| 340|Homo sapiens GNB1 protein. 77 7e-14
BT007305-1|AAP35969.1| 340|Homo sapiens guanine nucleotide bind... 77 7e-14
BC114618-1|AAI14619.1| 332|Homo sapiens GNB1 protein protein. 77 7e-14
BC035409-1|AAH35409.1| 808|Homo sapiens transducin (beta)-like ... 77 7e-14
BC021110-1|AAH21110.1| 421|Homo sapiens WD repeat and SOCS box-... 77 7e-14
BC014007-1|AAH14007.1| 808|Homo sapiens TBL3 protein protein. 77 7e-14
BC010231-1|AAH10231.1| 808|Homo sapiens transducin (beta)-like ... 77 7e-14
BC008991-1|AAH08991.1| 340|Homo sapiens guanine nucleotide bind... 77 7e-14
BC008082-1|AAH08082.1| 423|Homo sapiens WD repeat domain 12 pro... 77 7e-14
BC007620-1|AAH07620.1| 570|Homo sapiens TBL3 protein protein. 77 7e-14
BC005888-1|AAH05888.1| 340|Homo sapiens guanine nucleotide bind... 77 7e-14
BC004186-1|AAH04186.1| 340|Homo sapiens guanine nucleotide bind... 77 7e-14
AL356133-3|CAH72641.1| 738|Homo sapiens phospholipase A2-activa... 77 7e-14
AL109917-5|CAI95654.1| 340|Homo sapiens guanine nucleotide bind... 77 7e-14
AL031282-2|CAI20029.1| 340|Homo sapiens guanine nucleotide bind... 77 7e-14
AK223544-1|BAD97264.1| 748|Homo sapiens Hypothetical protein DK... 77 7e-14
AK074917-1|BAC11291.1| 421|Homo sapiens protein ( Homo sapiens ... 77 7e-14
AK001743-1|BAA91875.1| 423|Homo sapiens protein ( Homo sapiens ... 77 7e-14
AJ238243-1|CAB42881.1| 738|Homo sapiens phospholipase A2 activa... 77 7e-14
AF501882-1|AAM15918.1| 340|Homo sapiens guanine nucleotide bind... 77 7e-14
AF112205-1|AAF17193.1| 421|Homo sapiens WSB-1 protein protein. 77 7e-14
AF083395-1|AAD03030.1| 738|Homo sapiens phospholipase A2-activa... 77 7e-14
AF072880-1|AAD28808.1| 421|Homo sapiens SOCS box-containing WD ... 77 7e-14
AF069313-1|AAD20954.2| 421|Homo sapiens WSB1 protein protein. 77 7e-14
AC010900-2|AAY24287.1| 423|Homo sapiens unknown protein. 77 7e-14
AB209173-1|BAD92410.1| 832|Homo sapiens transducin beta-like 3 ... 77 7e-14
BC026213-1|AAH26213.1| 529|Homo sapiens F-box and WD repeat dom... 77 1e-13
BC010080-1|AAH10080.1| 305|Homo sapiens WD repeat domain 61 pro... 77 1e-13
AK024754-1|BAB14986.1| 305|Homo sapiens protein ( Homo sapiens ... 77 1e-13
AF309553-1|AAG31639.1| 305|Homo sapiens meiotic recombination p... 77 1e-13
AF176022-1|AAF04528.1| 542|Homo sapiens F-box protein Fbw1b pro... 77 1e-13
AF100786-1|AAP97225.1| 305|Homo sapiens G protein beta subunit-... 77 1e-13
AB033281-1|BAA92331.1| 542|Homo sapiens F-box and WD-repeats pr... 77 1e-13
AB033280-1|BAA92330.1| 529|Homo sapiens F-box and WD-repeats pr... 77 1e-13
AB033279-1|BAA92329.1| 508|Homo sapiens F-box and WD-repeats pr... 77 1e-13
AB014596-1|BAA31671.1| 550|Homo sapiens KIAA0696 protein protein. 77 1e-13
AF145020-1|AAD42075.1| 649|Homo sapiens phospholipase A2 activa... 76 1e-13
CR457333-1|CAG33614.1| 305|Homo sapiens REC14 protein. 76 2e-13
BC013997-1|AAH13997.1| 353|Homo sapiens guanine nucleotide bind... 76 2e-13
AF501885-1|AAM15921.1| 353|Homo sapiens guanine nucleotide bind... 76 2e-13
AF300650-1|AAG18444.1| 395|Homo sapiens guanine nucleotide bind... 76 2e-13
AF017656-1|AAC63826.1| 353|Homo sapiens G protein beta 5 subuni... 76 2e-13
AK001642-1|BAA91803.1| 795|Homo sapiens protein ( Homo sapiens ... 75 3e-13
AK131444-1|BAD18589.1| 472|Homo sapiens protein ( Homo sapiens ... 75 4e-13
AK074217-1|BAB85020.1| 506|Homo sapiens protein ( Homo sapiens ... 74 5e-13
AK222576-1|BAD96296.1| 421|Homo sapiens WD SOCS-box protein 1 i... 74 7e-13
BC015887-1|AAH15887.1| 404|Homo sapiens WD repeat and SOCS box-... 73 1e-12
AF229181-1|AAF71302.1| 404|Homo sapiens CS box-containing WD pr... 73 1e-12
AF163324-1|AAF80478.1| 404|Homo sapiens WSB-2 protein. 73 1e-12
AF106683-1|AAD43036.1| 421|Homo sapiens WSB-1 protein. 73 2e-12
AF070603-1|AAC28655.1| 207|Homo sapiens beta-subunit signal tra... 72 3e-12
BC028364-1|AAH28364.1| 1061|Homo sapiens FBXW10 protein protein. 71 5e-12
AY729024-1|AAU43731.1| 1052|Homo sapiens ubiquitin ligase specif... 71 5e-12
AB209899-1|BAD93136.1| 967|Homo sapiens Hypothetical protein DK... 71 5e-12
Y12050-1|CAA72779.1| 340|Homo sapiens guanine nucleotide-bindin... 71 6e-12
X74262-1|CAA52321.1| 425|Homo sapiens retinoblastoma binding pr... 71 6e-12
X71810-1|CAA50685.1| 410|Homo sapiens IEF SSP 9306 protein. 71 6e-12
U47924-5|AAB51313.1| 340|Homo sapiens G-protein beta-3 chain pr... 71 6e-12
M31328-1|AAA52582.1| 340|Homo sapiens GNB3 protein. 71 6e-12
BT009800-1|AAP88802.1| 340|Homo sapiens guanine nucleotide bind... 71 6e-12
BT007309-1|AAP35973.1| 425|Homo sapiens retinoblastoma binding ... 71 6e-12
BC075836-1|AAH75836.1| 425|Homo sapiens retinoblastoma binding ... 71 6e-12
BC053904-1|AAH53904.1| 425|Homo sapiens retinoblastoma binding ... 71 6e-12
BC015123-1|AAH15123.1| 365|Homo sapiens Similar to retinoblasto... 71 6e-12
BC003092-1|AAH03092.1| 425|Homo sapiens retinoblastoma binding ... 71 6e-12
BC002454-1|AAH02454.1| 340|Homo sapiens guanine nucleotide bind... 71 6e-12
BC000115-1|AAH00115.1| 340|Homo sapiens guanine nucleotide bind... 71 6e-12
AY631872-1|AAT38116.1| 340|Homo sapiens guanine nucleotide bind... 71 6e-12
AK222779-1|BAD96499.1| 424|Homo sapiens retinoblastoma binding ... 71 6e-12
AF501884-1|AAM15920.1| 340|Homo sapiens guanine nucleotide bind... 71 6e-12
AB209283-1|BAD92520.1| 327|Homo sapiens guanine nucleotide-bind... 71 6e-12
X72841-1|CAA51360.1| 425|Homo sapiens IEF 7442 protein. 70 8e-12
U35143-1|AAC50231.1| 425|Homo sapiens retinoblastoma-binding pr... 70 8e-12
CR541701-1|CAG46502.1| 425|Homo sapiens RBBP7 protein. 70 8e-12
BT020045-1|AAV38848.1| 350|Homo sapiens unr-interacting protein... 70 8e-12
BT020044-1|AAV38847.1| 350|Homo sapiens unr-interacting protein... 70 8e-12
BC114501-1|AAI14502.1| 425|Homo sapiens retinoblastoma binding ... 70 8e-12
BC114500-1|AAI14501.1| 425|Homo sapiens retinoblastoma binding ... 70 8e-12
BC062306-1|AAH62306.1| 350|Homo sapiens serine/threonine kinase... 70 8e-12
BC015920-1|AAH15920.1| 297|Homo sapiens GNB3 protein protein. 70 8e-12
BC000162-1|AAH00162.1| 350|Homo sapiens serine/threonine kinase... 70 8e-12
AY049776-1|AAL15433.1| 350|Homo sapiens unr-interacting protein... 70 8e-12
AL929302-6|CAI41284.1| 420|Homo sapiens retinoblastoma binding ... 70 8e-12
AL929302-5|CAI41283.1| 469|Homo sapiens retinoblastoma binding ... 70 8e-12
AJ010025-1|CAB38041.1| 350|Homo sapiens unr-interacting protein... 70 8e-12
AB024327-1|BAA75544.1| 350|Homo sapiens WD-40 repeat protein pr... 70 8e-12
AB013463-1|BAA86955.1| 404|Homo sapiens Fzr2 protein. 70 8e-12
AB013462-1|BAA86954.1| 496|Homo sapiens Fzr1 protein. 70 8e-12
BT007115-1|AAP35779.1| 493|Homo sapiens Fzr1 protein protein. 70 1e-11
BC013413-1|AAH13413.1| 493|Homo sapiens fizzy/cell division cyc... 70 1e-11
AF433157-1|AAL28117.1| 404|Homo sapiens CDC20-like 1b protein. 70 1e-11
AF083810-1|AAD52030.1| 493|Homo sapiens fizzy-related protein p... 70 1e-11
AC005787-1|AAC62835.1| 493|Homo sapiens R33374_1 protein. 70 1e-11
AB033068-1|BAA86556.1| 504|Homo sapiens KIAA1242 protein protein. 70 1e-11
BC005870-1|AAH05870.1| 315|Homo sapiens mitogen-activated prote... 69 1e-11
AF240696-1|AAF82746.1| 275|Homo sapiens WSB1 isoform 2 protein. 69 1e-11
BC012352-1|AAH12352.1| 366|Homo sapiens WDR31 protein protein. 69 2e-11
AL449305-1|CAI10961.1| 367|Homo sapiens WD repeat domain 31 pro... 69 2e-11
AL137066-1|CAH70096.1| 367|Homo sapiens WD repeat domain 31 pro... 69 2e-11
AL031282-15|CAI20051.1| 197|Homo sapiens guanine nucleotide bin... 69 2e-11
AK223195-1|BAD96915.1| 315|Homo sapiens mitogen-activated prote... 69 2e-11
AK093240-1|BAC04106.1| 367|Homo sapiens protein ( Homo sapiens ... 69 2e-11
AB023199-1|BAA76826.2| 502|Homo sapiens KIAA0982 protein protein. 69 2e-11
U24105-1|AAB70879.1| 1224|Homo sapiens coatomer protein protein. 68 3e-11
BC038447-1|AAH38447.1| 1233|Homo sapiens COPA protein protein. 68 3e-11
AL513282-3|CAI12455.1| 1233|Homo sapiens coatomer protein comple... 68 3e-11
AL513282-2|CAI12454.1| 1224|Homo sapiens coatomer protein comple... 68 3e-11
AL445230-2|CAI15004.1| 1233|Homo sapiens coatomer protein comple... 68 3e-11
AL445230-1|CAI15005.1| 1224|Homo sapiens coatomer protein comple... 68 3e-11
AF080397-1|AAF20266.1| 493|Homo sapiens fizzy-related protein h... 68 3e-11
AF127799-1|AAP97249.1| 305|Homo sapiens G protein beta subunit-... 68 5e-11
AL607085-2|CAI15166.1| 494|Homo sapiens WD repeat domain 37 pro... 67 6e-11
EF560734-1|ABQ59044.1| 588|Homo sapiens ATG16L1 protein protein. 65 2e-10
EF079890-1|ABN48555.1| 444|Homo sapiens ATG16 autophagy related... 65 2e-10
EF079889-1|ABN48554.1| 588|Homo sapiens ATG16 autophagy related... 65 2e-10
BC117337-1|AAI17338.1| 523|Homo sapiens ATG16L1 protein protein. 65 2e-10
BC071846-1|AAH71846.1| 475|Homo sapiens ATG16L1 protein protein. 65 2e-10
AY398617-1|AAR32130.1| 607|Homo sapiens APG16L beta protein. 65 2e-10
AK123876-1|BAC85713.1| 428|Homo sapiens protein ( Homo sapiens ... 65 2e-10
AK027854-1|BAB55412.1| 504|Homo sapiens protein ( Homo sapiens ... 65 2e-10
AC013726-3|AAY14860.1| 523|Homo sapiens unknown protein. 65 2e-10
X95263-1|CAA64560.1| 919|Homo sapiens PWP2 protein. 63 1e-09
U56089-1|AAC50905.1| 919|Homo sapiens periodic tryptophan prote... 63 1e-09
U56085-1|AAC50904.1| 919|Homo sapiens periodic tryptophan prote... 63 1e-09
U53346-1|AAB08084.1| 919|Homo sapiens PWP2H protein protein. 63 1e-09
BC014988-1|AAH14988.1| 919|Homo sapiens PWP2 periodic tryptopha... 63 1e-09
BC013309-1|AAH13309.1| 919|Homo sapiens PWP2 periodic tryptopha... 63 1e-09
AP001753-1|BAA95553.1| 919|Homo sapiens periodic tryptophan pro... 63 1e-09
AB209438-1|BAD92675.1| 316|Homo sapiens PWP2 periodic tryptopha... 63 1e-09
AB001517-2|BAA21137.1| 919|Homo sapiens PWP2 protein protein. 63 1e-09
BC018698-1|AAH18698.1| 504|Homo sapiens PRP19/PSO4 pre-mRNA pro... 62 2e-09
BC018665-1|AAH18665.1| 504|Homo sapiens PRP19/PSO4 pre-mRNA pro... 62 2e-09
BC008719-1|AAH08719.1| 504|Homo sapiens PRP19/PSO4 pre-mRNA pro... 62 2e-09
AJ131186-1|CAB51857.1| 504|Homo sapiens nuclear matrix protein ... 62 2e-09
AL121993-4|CAI22739.1| 943|Homo sapiens WD repeat domain 3 prot... 62 2e-09
AF083217-1|AAD45865.1| 943|Homo sapiens WD repeat protein WDR3 ... 62 2e-09
AB209201-1|BAD92438.1| 466|Homo sapiens WD repeat-containing pr... 62 2e-09
U86136-1|AAC51107.1| 2627|Homo sapiens telomerase-associated pro... 62 3e-09
DQ924532-1|ABK76299.1| 1821|Homo sapiens pleckstrin homology dom... 62 3e-09
BC126114-1|AAI26115.1| 579|Homo sapiens cell division cycle 40 ... 62 3e-09
BC126107-1|AAI26108.1| 2627|Homo sapiens telomerase-associated p... 62 3e-09
BC117145-1|AAI17146.1| 579|Homo sapiens cell division cycle 40 ... 62 3e-09
BC021905-1|AAH21905.1| 896|Homo sapiens Unknown (protein for IM... 62 3e-09
AY336091-1|AAR24621.1| 352|Homo sapiens migration-inducing gene... 62 3e-09
AL671518-2|CAI13322.1| 579|Homo sapiens cell division cycle 40 ... 62 3e-09
AL671518-1|CAI13321.1| 539|Homo sapiens cell division cycle 40 ... 62 3e-09
AL450327-2|CAH70884.1| 1821|Homo sapiens protein ( vel protein (... 62 3e-09
AL445068-1|CAI22519.1| 539|Homo sapiens cell division cycle 40 ... 62 3e-09
AL356776-2|CAI14406.1| 1821|Homo sapiens protein ( Human DNA seq... 62 3e-09
AK057039-1|BAB71353.1| 912|Homo sapiens protein ( Homo sapiens ... 62 3e-09
AJ303102-1|CAC83118.1| 1821|Homo sapiens WD repeat domain 11 pro... 62 3e-09
AF061241-1|AAC25166.1| 542|Homo sapiens splicing factor hPRP17 ... 62 3e-09
AF038392-1|AAC39730.1| 579|Homo sapiens pre-mRNA splicing facto... 62 3e-09
AB209669-1|BAD92906.1| 1903|Homo sapiens Telomerase protein comp... 62 3e-09
AB208903-1|BAD92140.1| 501|Homo sapiens pre-mRNA splicing facto... 62 3e-09
BC111490-1|AAI11491.1| 768|Homo sapiens BRWD3 protein protein. 61 4e-09
BC068499-1|AAH68499.1| 351|Homo sapiens THO complex 3 protein. 61 4e-09
BC066325-1|AAH66325.1| 327|Homo sapiens THOC3 protein protein. 61 4e-09
BC006849-1|AAH06849.1| 351|Homo sapiens THO complex 3 protein. 61 4e-09
AY497047-1|AAS45472.1| 1631|Homo sapiens bromodomain and WD repe... 61 4e-09
AY497046-1|AAS45471.1| 1802|Homo sapiens bromodomain and WD repe... 61 4e-09
AY358182-1|AAQ88549.1| 470|Homo sapiens SSGL9393 protein. 61 4e-09
AL669934-1|CAI95405.1| 1802|Homo sapiens bromodomain and WD repe... 61 4e-09
AL590031-1|CAI39936.2| 1802|Homo sapiens bromodomain and WD repe... 61 4e-09
AL512504-2|CAI95143.1| 1802|Homo sapiens bromodomain and WD repe... 61 4e-09
BX679664-5|CAH71325.1| 891|Homo sapiens WD repeat domain 47 pro... 61 5e-09
BX679664-4|CAH71327.1| 919|Homo sapiens WD repeat domain 47 pro... 61 5e-09
BX679664-3|CAH71326.1| 920|Homo sapiens WD repeat domain 47 pro... 61 5e-09
BC039254-1|AAH39254.1| 893|Homo sapiens WDR47 protein protein. 61 5e-09
AL449266-4|CAI14352.1| 891|Homo sapiens WD repeat domain 47 pro... 61 5e-09
AL449266-3|CAI14353.1| 919|Homo sapiens WD repeat domain 47 pro... 61 5e-09
AL449266-2|CAI14351.1| 920|Homo sapiens WD repeat domain 47 pro... 61 5e-09
AL163279-2|CAB90452.1| 2295|Homo sapiens homolog to cAMP respons... 61 5e-09
AK222721-1|BAD96441.1| 579|Homo sapiens pre-mRNA splicing facto... 61 5e-09
AK131383-1|BAD18534.1| 141|Homo sapiens protein ( Homo sapiens ... 61 5e-09
AJ292466-1|CAC44372.1| 2269|Homo sapiens WDR9 protein, form B p... 61 5e-09
AJ292465-1|CAC44371.1| 2320|Homo sapiens WDR9 protein, form A pr... 61 5e-09
AJ238214-1|CAC37033.2| 2269|Homo sapiens hypothetical protein pr... 61 5e-09
AB080587-1|BAD74072.1| 2199|Homo sapiens WD repeat protein WDR9-... 61 5e-09
AB080586-1|BAD74071.1| 2269|Homo sapiens WD repeat protein protein. 61 5e-09
AB020700-1|BAA74916.2| 974|Homo sapiens KIAA0893 protein protein. 61 5e-09
BC110334-1|AAI10335.1| 454|Homo sapiens F-box and WD repeat dom... 60 7e-09
BC018738-1|AAH18738.1| 454|Homo sapiens F-box and WD repeat dom... 60 7e-09
AL161911-3|CAI95114.1| 208|Homo sapiens F-box and WD repeat dom... 60 7e-09
AL161911-2|CAI95113.1| 454|Homo sapiens F-box and WD repeat dom... 60 7e-09
AK022484-1|BAB14051.1| 454|Homo sapiens protein ( Homo sapiens ... 60 7e-09
AF176698-1|AAF13226.1| 422|Homo sapiens F-box protein FBW2 prot... 60 7e-09
AF145024-1|AAP97276.1| 422|Homo sapiens MD6 protein protein. 60 7e-09
AF129531-1|AAF04465.1| 422|Homo sapiens F-box protein Fbw2 prot... 60 7e-09
BC036713-1|AAH36713.1| 542|Homo sapiens ATG16L2 protein protein. 60 9e-09
BC034964-1|AAH34964.1| 920|Homo sapiens WD repeat domain 47 pro... 60 9e-09
AK090597-1|BAC03485.1| 513|Homo sapiens protein ( Homo sapiens ... 60 9e-09
AK074434-1|BAB85082.1| 293|Homo sapiens protein ( Homo sapiens ... 60 9e-09
U84720-1|AAC28126.1| 368|Homo sapiens mRNA export protein protein. 60 1e-08
BC106924-1|AAI06925.1| 368|Homo sapiens RAE1 RNA export 1 homol... 60 1e-08
BC106923-1|AAI06924.1| 368|Homo sapiens RAE1 RNA export 1 homol... 60 1e-08
BC103754-1|AAI03755.1| 368|Homo sapiens RAE1 RNA export 1 homol... 60 1e-08
AY349350-1|AAR04856.1| 368|Homo sapiens RNA export 1-like prote... 60 1e-08
AL135939-7|CAI21524.1| 368|Homo sapiens RAE1 RNA export 1 homol... 60 1e-08
AK093017-1|BAC04021.1| 619|Homo sapiens protein ( Homo sapiens ... 60 1e-08
U63810-1|AAC24948.1| 339|Homo sapiens WD40 protein Ciao 1 protein. 59 2e-08
EF011618-1|ABK41108.1| 339|Homo sapiens CDW8/WDR39 protein. 59 2e-08
CR456802-1|CAG33083.1| 339|Homo sapiens CIAO1 protein. 59 2e-08
BC032812-1|AAH32812.1| 339|Homo sapiens cytosolic iron-sulfur p... 59 2e-08
BC024267-1|AAH24267.1| 594|Homo sapiens TRAF7 protein protein. 59 2e-08
BC001395-1|AAH01395.1| 339|Homo sapiens cytosolic iron-sulfur p... 59 2e-08
AY569455-1|AAS68363.1| 670|Homo sapiens TRAF7 protein. 59 2e-08
AK223257-1|BAD96977.1| 339|Homo sapiens WD40 protein Ciao1 vari... 59 2e-08
AJ005257-1|CAA06444.1| 86|Homo sapiens protein ( Homo sapiens ... 59 2e-08
AC004020-1|AAC23493.1| 339|Homo sapiens Unknown gene product pr... 59 2e-08
U88871-1|AAC51238.1| 323|Homo sapiens HsPex7p protein. 59 2e-08
U76560-1|AAB50556.1| 323|Homo sapiens peroxisome targeting sign... 59 2e-08
CR542076-1|CAG46873.1| 323|Homo sapiens PEX7 protein. 59 2e-08
CR542054-1|CAG46851.1| 323|Homo sapiens PEX7 protein. 59 2e-08
BC006268-1|AAH06268.1| 323|Homo sapiens peroxisomal biogenesis ... 59 2e-08
AL365223-4|CAI15714.1| 323|Homo sapiens peroxisomal biogenesis ... 59 2e-08
AL121933-2|CAI15471.1| 323|Homo sapiens peroxisomal biogenesis ... 59 2e-08
AF180814-1|AAF37350.1| 323|Homo sapiens peroxisomal PTS2 recept... 59 2e-08
U05340-1|AAA19017.1| 499|Homo sapiens p55CDC protein. 58 3e-08
DQ473545-1|ABE96834.1| 499|Homo sapiens CDC20 cell division cyc... 58 3e-08
BT007388-1|AAP36052.1| 499|Homo sapiens CDC20 cell division cyc... 58 3e-08
BC110321-1|AAI10322.1| 499|Homo sapiens cell division cycle 20 ... 58 3e-08
BC031294-1|AAH31294.1| 499|Homo sapiens cell division cycle 20 ... 58 3e-08
BC024257-1|AAH24257.1| 499|Homo sapiens cell division cycle 20 ... 58 3e-08
BC015998-1|AAH15998.1| 499|Homo sapiens cell division cycle 20 ... 58 3e-08
BC013303-1|AAH13303.1| 499|Homo sapiens cell division cycle 20 ... 58 3e-08
BC012827-1|AAH12827.1| 499|Homo sapiens cell division cycle 20 ... 58 3e-08
BC012803-1|AAH12803.1| 499|Homo sapiens cell division cycle 20 ... 58 3e-08
BC010044-1|AAH10044.1| 499|Homo sapiens cell division cycle 20 ... 58 3e-08
BC009426-1|AAH09426.1| 499|Homo sapiens cell division cycle 20 ... 58 3e-08
BC009425-1|AAH09425.1| 499|Homo sapiens cell division cycle 20 ... 58 3e-08
BC006272-1|AAH06272.1| 499|Homo sapiens cell division cycle 20 ... 58 3e-08
BC001088-1|AAH01088.1| 499|Homo sapiens cell division cycle 20 ... 58 3e-08
BC000624-1|AAH00624.1| 499|Homo sapiens CDC20 protein protein. 58 3e-08
AL139289-3|CAB92757.1| 499|Homo sapiens cell division cycle 20 ... 58 3e-08
AF099644-1|AAD16405.1| 499|Homo sapiens cell cycle protein CDC2... 58 3e-08
L02547-1|AAA35691.1| 431|Homo sapiens cleavage stimulation fact... 58 4e-08
BT007138-1|AAP35802.1| 431|Homo sapiens cleavage stimulation fa... 58 4e-08
BC007425-1|AAH07425.1| 431|Homo sapiens cleavage stimulation fa... 58 4e-08
BC001011-1|AAH01011.1| 431|Homo sapiens cleavage stimulation fa... 58 4e-08
AL121914-12|CAI19328.1| 431|Homo sapiens cleavage stimulation f... 58 4e-08
U85943-1|AAC28127.1| 368|Homo sapiens mRNA-associated protein m... 58 5e-08
BC094728-1|AAH94728.1| 731|Homo sapiens ring finger and WD repe... 58 5e-08
AY509921-1|AAS82851.1| 707|Homo sapiens constitutive photomorph... 58 5e-08
AL590723-3|CAI14643.1| 731|Homo sapiens ring finger and WD repe... 58 5e-08
AL590723-2|CAI14642.1| 564|Homo sapiens ring finger and WD repe... 58 5e-08
AL590723-1|CAI14641.1| 491|Homo sapiens ring finger and WD repe... 58 5e-08
AL513329-4|CAH72425.1| 731|Homo sapiens ring finger and WD repe... 58 5e-08
AL513329-2|CAH72423.1| 564|Homo sapiens ring finger and WD repe... 58 5e-08
AL513329-1|CAH72422.1| 491|Homo sapiens ring finger and WD repe... 58 5e-08
AL359265-3|CAH71140.1| 731|Homo sapiens ring finger and WD repe... 58 5e-08
AL359265-2|CAH71139.1| 564|Homo sapiens ring finger and WD repe... 58 5e-08
AL359265-1|CAH71138.1| 491|Homo sapiens ring finger and WD repe... 58 5e-08
AL162736-3|CAH73625.1| 731|Homo sapiens ring finger and WD repe... 58 5e-08
AL162736-2|CAH73624.1| 564|Homo sapiens ring finger and WD repe... 58 5e-08
AL162736-1|CAH73623.1| 491|Homo sapiens ring finger and WD repe... 58 5e-08
AK025789-1|BAB15239.1| 506|Homo sapiens protein ( Homo sapiens ... 58 5e-08
AF527539-1|AAQ08989.1| 731|Homo sapiens putative ubiquitin liga... 58 5e-08
AF508940-1|AAM34692.1| 731|Homo sapiens constitutive photomorph... 58 5e-08
CR456496-1|CAG30382.1| 327|Homo sapiens GNB1L protein. 57 6e-08
BC067132-1|AAH67132.1| 546|Homo sapiens WDR23 protein protein. 57 6e-08
BC012060-1|AAH12060.1| 327|Homo sapiens guanine nucleotide bind... 57 6e-08
AK074296-1|BAB85041.1| 546|Homo sapiens protein ( Homo sapiens ... 57 6e-08
AF492460-1|AAN64030.1| 1322|Homo sapiens WD repeat 17 protein. 57 6e-08
AF301895-1|AAG53933.1| 327|Homo sapiens WDVCF protein. 57 6e-08
AF267858-1|AAG44727.1| 548|Homo sapiens GL014 protein. 57 6e-08
AB209073-1|BAD92310.1| 469|Homo sapiens WD repeat domain 23 iso... 57 6e-08
AB051432-1|BAB33315.1| 386|Homo sapiens KIAA1645 protein protein. 57 6e-08
AB049212-1|BAB68408.1| 327|Homo sapiens G-protein beta subunit ... 57 6e-08
M99439-1|AAA61195.1| 448|Homo sapiens transducin-like enhancer ... 57 8e-08
BC117291-1|AAI17292.1| 925|Homo sapiens coronin 7 protein. 57 8e-08
BC117289-1|AAI17290.1| 925|Homo sapiens coronin 7 protein. 57 8e-08
AL929302-3|CAI41281.1| 175|Homo sapiens retinoblastoma binding ... 57 8e-08
AK025674-1|BAB15211.1| 925|Homo sapiens protein ( Homo sapiens ... 57 8e-08
BC059405-1|AAH59405.2| 805|Homo sapiens TLE4 protein protein. 56 1e-07
BC045650-1|AAH45650.1| 704|Homo sapiens TLE4 protein protein. 56 1e-07
AL445252-3|CAI13644.1| 764|Homo sapiens transducin-like enhance... 56 1e-07
AL358975-3|CAI13734.1| 764|Homo sapiens transducin-like enhance... 56 1e-07
AL353813-5|CAI41315.1| 764|Homo sapiens transducin-like enhance... 56 1e-07
AB033087-1|BAA86575.1| 787|Homo sapiens KIAA1261 protein protein. 56 1e-07
AB010098-1|BAA36341.1| 475|Homo sapiens ClipinC protein. 56 1e-07
M99436-1|AAA61193.1| 743|Homo sapiens transducin-like enhancer ... 56 1e-07
BC047572-1|AAH47572.1| 433|Homo sapiens KIF21A protein protein. 56 1e-07
BC028628-1|AAH28628.1| 375|Homo sapiens WDR71 protein protein. 56 1e-07
BC021541-1|AAH21541.1| 392|Homo sapiens WD repeat domain 71 pro... 56 1e-07
BC006142-1|AAH06142.2| 392|Homo sapiens WD repeat domain 71 pro... 56 1e-07
AY583459-1|AAS90945.1| 764|Homo sapiens transducin-like enhance... 56 1e-07
AY368076-1|AAR04774.1| 1674|Homo sapiens kinesin family member 2... 56 1e-07
AM177179-1|CAJ45483.1| 1621|Homo sapiens kinesin-like protein KI... 56 1e-07
AL121914-11|CAC12718.2| 345|Homo sapiens cleavage stimulation f... 56 1e-07
AK021910-1|BAB13933.1| 392|Homo sapiens protein ( Homo sapiens ... 56 1e-07
AF450487-1|AAP97680.1| 1662|Homo sapiens kinesin-like protein KI... 56 1e-07
AF087895-1|AAP97194.1| 375|Homo sapiens G-16 protein. 56 1e-07
AB051495-1|BAB21799.2| 1657|Homo sapiens KIAA1708 protein. 56 1e-07
X96586-1|CAA65405.1| 917|Homo sapiens FAN protein protein. 56 2e-07
M99438-1|AAA61194.1| 772|Homo sapiens transducin-like enhancer ... 56 2e-07
BC043247-1|AAH43247.1| 767|Homo sapiens TLE3 protein protein. 56 2e-07
BC041831-1|AAH41831.1| 772|Homo sapiens TLE3 protein protein. 56 2e-07
BC026335-1|AAH26335.1| 475|Homo sapiens coronin, actin binding ... 56 2e-07
BC022438-1|AAH22438.1| 328|Homo sapiens BUB3 budding uninhibite... 56 2e-07
BC005138-1|AAH05138.1| 328|Homo sapiens BUB3 budding uninhibite... 56 2e-07
AF081496-1|AAC36307.1| 328|Homo sapiens kinetochore protein BUB... 56 2e-07
AF053304-1|AAC06258.1| 328|Homo sapiens mitotic checkpoint comp... 56 2e-07
AF047473-1|AAC28439.1| 326|Homo sapiens testis mitotic checkpoi... 56 2e-07
AF047472-1|AAC28438.1| 328|Homo sapiens spleen mitotic checkpoi... 56 2e-07
AB046767-1|BAB13373.1| 863|Homo sapiens KIAA1547 protein protein. 56 2e-07
AB023142-1|BAA76769.1| 479|Homo sapiens KIAA0925 protein protein. 56 2e-07
BC025392-1|AAH25392.1| 620|Homo sapiens WD repeat domain 16 pro... 55 3e-07
AK094847-1|BAC04435.1| 630|Homo sapiens protein ( Homo sapiens ... 55 3e-07
AK074435-1|BAB85083.1| 412|Homo sapiens protein ( Homo sapiens ... 55 3e-07
AB065281-1|BAB83743.1| 620|Homo sapiens WDR16 protein. 55 3e-07
BC041124-1|AAH41124.1| 917|Homo sapiens neutral sphingomyelinas... 55 3e-07
BC008858-1|AAH08858.2| 383|Homo sapiens WDR23 protein protein. 55 3e-07
AK222501-1|BAD96221.1| 392|Homo sapiens hypothetical protein FL... 55 3e-07
AK074891-1|BAC11271.1| 242|Homo sapiens protein ( Homo sapiens ... 55 3e-07
AB080593-1|BAD74078.1| 265|Homo sapiens WD repeat protein protein. 55 3e-07
AB080591-1|BAD74076.1| 547|Homo sapiens WD repeat protein protein. 55 3e-07
AB080589-1|BAD74074.1| 466|Homo sapiens WD repeat protein protein. 55 3e-07
AB080588-1|BAD74073.1| 408|Homo sapiens WD repeat protein protein. 55 3e-07
BX537855-1|CAD97863.1| 974|Homo sapiens hypothetical protein pr... 54 4e-07
AK026330-1|BAB15448.1| 173|Homo sapiens protein ( Homo sapiens ... 54 4e-07
AB080592-1|BAD74077.1| 234|Homo sapiens WD repeat protein protein. 54 4e-07
AK024435-1|BAB15725.1| 955|Homo sapiens FLJ00025 protein protein. 54 6e-07
BC017364-1|AAH17364.1| 743|Homo sapiens transducin-like enhance... 54 8e-07
BC010907-1|AAH10907.1| 392|Homo sapiens PAK1 interacting protei... 54 8e-07
>M24194-1|AAA59626.1| 317|Homo sapiens MHC B complex protein 12.3
protein.
Length = 317
Score = 419 bits (1031), Expect = e-117
Identities = 183/228 (80%), Positives = 205/228 (89%)
Frame = +2
Query: 113 MSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLY 292
M+E + LRGTL+GHNGWVTQIAT P++PDMILS+SRDKT+I+WKLTRDE NYGIPQ+ L
Sbjct: 1 MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALR 60
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI 472
GHSHF+SDVV+SSDG +ALSGSWD TLRLWDL G TTRRF HTKDVLSVAFS DNRQI
Sbjct: 61 GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQI 120
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
VSGSRDKTIKLWNTL CKYT+QD+ HS+WVSCVRFSPN +NPIIVSCGWD+ VKVW+L
Sbjct: 121 VSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLA 180
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
NCKLK NH+GH+GYLNTVTVSPDGSLCASGGKD AMLWDLN+GKHL+
Sbjct: 181 NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLY 228
>CR541909-1|CAG46707.1| 317|Homo sapiens GNB2L1 protein.
Length = 317
Score = 419 bits (1031), Expect = e-117
Identities = 183/228 (80%), Positives = 205/228 (89%)
Frame = +2
Query: 113 MSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLY 292
M+E + LRGTL+GHNGWVTQIAT P++PDMILS+SRDKT+I+WKLTRDE NYGIPQ+ L
Sbjct: 1 MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALR 60
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI 472
GHSHF+SDVV+SSDG +ALSGSWD TLRLWDL G TTRRF HTKDVLSVAFS DNRQI
Sbjct: 61 GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQI 120
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
VSGSRDKTIKLWNTL CKYT+QD+ HS+WVSCVRFSPN +NPIIVSCGWD+ VKVW+L
Sbjct: 121 VSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLA 180
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
NCKLK NH+GH+GYLNTVTVSPDGSLCASGGKD AMLWDLN+GKHL+
Sbjct: 181 NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLY 228
>CR456978-1|CAG33259.1| 317|Homo sapiens GNB2L1 protein.
Length = 317
Score = 419 bits (1031), Expect = e-117
Identities = 183/228 (80%), Positives = 205/228 (89%)
Frame = +2
Query: 113 MSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLY 292
M+E + LRGTL+GHNGWVTQIAT P++PDMILS+SRDKT+I+WKLTRDE NYGIPQ+ L
Sbjct: 1 MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALR 60
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI 472
GHSHF+SDVV+SSDG +ALSGSWD TLRLWDL G TTRRF HTKDVLSVAFS DNRQI
Sbjct: 61 GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQI 120
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
VSGSRDKTIKLWNTL CKYT+QD+ HS+WVSCVRFSPN +NPIIVSCGWD+ VKVW+L
Sbjct: 121 VSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLA 180
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
NCKLK NH+GH+GYLNTVTVSPDGSLCASGGKD AMLWDLN+GKHL+
Sbjct: 181 NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLY 228
>BC032006-1|AAH32006.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 419 bits (1031), Expect = e-117
Identities = 183/228 (80%), Positives = 205/228 (89%)
Frame = +2
Query: 113 MSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLY 292
M+E + LRGTL+GHNGWVTQIAT P++PDMILS+SRDKT+I+WKLTRDE NYGIPQ+ L
Sbjct: 1 MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALR 60
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI 472
GHSHF+SDVV+SSDG +ALSGSWD TLRLWDL G TTRRF HTKDVLSVAFS DNRQI
Sbjct: 61 GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQI 120
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
VSGSRDKTIKLWNTL CKYT+QD+ HS+WVSCVRFSPN +NPIIVSCGWD+ VKVW+L
Sbjct: 121 VSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLA 180
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
NCKLK NH+GH+GYLNTVTVSPDGSLCASGGKD AMLWDLN+GKHL+
Sbjct: 181 NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLY 228
>BC021993-1|AAH21993.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 419 bits (1031), Expect = e-117
Identities = 183/228 (80%), Positives = 205/228 (89%)
Frame = +2
Query: 113 MSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLY 292
M+E + LRGTL+GHNGWVTQIAT P++PDMILS+SRDKT+I+WKLTRDE NYGIPQ+ L
Sbjct: 1 MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALR 60
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI 472
GHSHF+SDVV+SSDG +ALSGSWD TLRLWDL G TTRRF HTKDVLSVAFS DNRQI
Sbjct: 61 GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQI 120
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
VSGSRDKTIKLWNTL CKYT+QD+ HS+WVSCVRFSPN +NPIIVSCGWD+ VKVW+L
Sbjct: 121 VSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLA 180
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
NCKLK NH+GH+GYLNTVTVSPDGSLCASGGKD AMLWDLN+GKHL+
Sbjct: 181 NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLY 228
>BC019362-1|AAH19362.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 419 bits (1031), Expect = e-117
Identities = 183/228 (80%), Positives = 205/228 (89%)
Frame = +2
Query: 113 MSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLY 292
M+E + LRGTL+GHNGWVTQIAT P++PDMILS+SRDKT+I+WKLTRDE NYGIPQ+ L
Sbjct: 1 MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALR 60
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI 472
GHSHF+SDVV+SSDG +ALSGSWD TLRLWDL G TTRRF HTKDVLSVAFS DNRQI
Sbjct: 61 GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQI 120
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
VSGSRDKTIKLWNTL CKYT+QD+ HS+WVSCVRFSPN +NPIIVSCGWD+ VKVW+L
Sbjct: 121 VSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLA 180
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
NCKLK NH+GH+GYLNTVTVSPDGSLCASGGKD AMLWDLN+GKHL+
Sbjct: 181 NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLY 228
>BC019093-1|AAH19093.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 419 bits (1031), Expect = e-117
Identities = 183/228 (80%), Positives = 205/228 (89%)
Frame = +2
Query: 113 MSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLY 292
M+E + LRGTL+GHNGWVTQIAT P++PDMILS+SRDKT+I+WKLTRDE NYGIPQ+ L
Sbjct: 1 MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALR 60
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI 472
GHSHF+SDVV+SSDG +ALSGSWD TLRLWDL G TTRRF HTKDVLSVAFS DNRQI
Sbjct: 61 GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQI 120
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
VSGSRDKTIKLWNTL CKYT+QD+ HS+WVSCVRFSPN +NPIIVSCGWD+ VKVW+L
Sbjct: 121 VSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLA 180
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
NCKLK NH+GH+GYLNTVTVSPDGSLCASGGKD AMLWDLN+GKHL+
Sbjct: 181 NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLY 228
>BC017287-1|AAH17287.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 419 bits (1031), Expect = e-117
Identities = 183/228 (80%), Positives = 205/228 (89%)
Frame = +2
Query: 113 MSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLY 292
M+E + LRGTL+GHNGWVTQIAT P++PDMILS+SRDKT+I+WKLTRDE NYGIPQ+ L
Sbjct: 1 MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALR 60
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI 472
GHSHF+SDVV+SSDG +ALSGSWD TLRLWDL G TTRRF HTKDVLSVAFS DNRQI
Sbjct: 61 GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQI 120
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
VSGSRDKTIKLWNTL CKYT+QD+ HS+WVSCVRFSPN +NPIIVSCGWD+ VKVW+L
Sbjct: 121 VSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLA 180
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
NCKLK NH+GH+GYLNTVTVSPDGSLCASGGKD AMLWDLN+GKHL+
Sbjct: 181 NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLY 228
>BC014788-1|AAH14788.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 419 bits (1031), Expect = e-117
Identities = 183/228 (80%), Positives = 205/228 (89%)
Frame = +2
Query: 113 MSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLY 292
M+E + LRGTL+GHNGWVTQIAT P++PDMILS+SRDKT+I+WKLTRDE NYGIPQ+ L
Sbjct: 1 MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALR 60
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI 472
GHSHF+SDVV+SSDG +ALSGSWD TLRLWDL G TTRRF HTKDVLSVAFS DNRQI
Sbjct: 61 GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQI 120
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
VSGSRDKTIKLWNTL CKYT+QD+ HS+WVSCVRFSPN +NPIIVSCGWD+ VKVW+L
Sbjct: 121 VSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLA 180
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
NCKLK NH+GH+GYLNTVTVSPDGSLCASGGKD AMLWDLN+GKHL+
Sbjct: 181 NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLY 228
>BC014256-1|AAH14256.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 419 bits (1031), Expect = e-117
Identities = 183/228 (80%), Positives = 205/228 (89%)
Frame = +2
Query: 113 MSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLY 292
M+E + LRGTL+GHNGWVTQIAT P++PDMILS+SRDKT+I+WKLTRDE NYGIPQ+ L
Sbjct: 1 MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALR 60
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI 472
GHSHF+SDVV+SSDG +ALSGSWD TLRLWDL G TTRRF HTKDVLSVAFS DNRQI
Sbjct: 61 GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQI 120
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
VSGSRDKTIKLWNTL CKYT+QD+ HS+WVSCVRFSPN +NPIIVSCGWD+ VKVW+L
Sbjct: 121 VSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLA 180
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
NCKLK NH+GH+GYLNTVTVSPDGSLCASGGKD AMLWDLN+GKHL+
Sbjct: 181 NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLY 228
>BC010119-1|AAH10119.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 419 bits (1031), Expect = e-117
Identities = 183/228 (80%), Positives = 205/228 (89%)
Frame = +2
Query: 113 MSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLY 292
M+E + LRGTL+GHNGWVTQIAT P++PDMILS+SRDKT+I+WKLTRDE NYGIPQ+ L
Sbjct: 1 MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALR 60
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI 472
GHSHF+SDVV+SSDG +ALSGSWD TLRLWDL G TTRRF HTKDVLSVAFS DNRQI
Sbjct: 61 GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQI 120
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
VSGSRDKTIKLWNTL CKYT+QD+ HS+WVSCVRFSPN +NPIIVSCGWD+ VKVW+L
Sbjct: 121 VSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLA 180
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
NCKLK NH+GH+GYLNTVTVSPDGSLCASGGKD AMLWDLN+GKHL+
Sbjct: 181 NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLY 228
>BC000366-1|AAH00366.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 419 bits (1031), Expect = e-117
Identities = 183/228 (80%), Positives = 205/228 (89%)
Frame = +2
Query: 113 MSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLY 292
M+E + LRGTL+GHNGWVTQIAT P++PDMILS+SRDKT+I+WKLTRDE NYGIPQ+ L
Sbjct: 1 MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALR 60
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI 472
GHSHF+SDVV+SSDG +ALSGSWD TLRLWDL G TTRRF HTKDVLSVAFS DNRQI
Sbjct: 61 GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQI 120
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
VSGSRDKTIKLWNTL CKYT+QD+ HS+WVSCVRFSPN +NPIIVSCGWD+ VKVW+L
Sbjct: 121 VSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLA 180
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
NCKLK NH+GH+GYLNTVTVSPDGSLCASGGKD AMLWDLN+GKHL+
Sbjct: 181 NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLY 228
>BC000214-1|AAH00214.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 419 bits (1031), Expect = e-117
Identities = 183/228 (80%), Positives = 205/228 (89%)
Frame = +2
Query: 113 MSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLY 292
M+E + LRGTL+GHNGWVTQIAT P++PDMILS+SRDKT+I+WKLTRDE NYGIPQ+ L
Sbjct: 1 MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALR 60
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI 472
GHSHF+SDVV+SSDG +ALSGSWD TLRLWDL G TTRRF HTKDVLSVAFS DNRQI
Sbjct: 61 GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQI 120
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
VSGSRDKTIKLWNTL CKYT+QD+ HS+WVSCVRFSPN +NPIIVSCGWD+ VKVW+L
Sbjct: 121 VSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLA 180
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
NCKLK NH+GH+GYLNTVTVSPDGSLCASGGKD AMLWDLN+GKHL+
Sbjct: 181 NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLY 228
>AY159316-1|AAO21313.1| 347|Homo sapiens lung cancer oncogene 7
protein.
Length = 347
Score = 419 bits (1031), Expect = e-117
Identities = 183/228 (80%), Positives = 205/228 (89%)
Frame = +2
Query: 113 MSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLY 292
M+E + LRGTL+GHNGWVTQIAT P++PDMILS+SRDKT+I+WKLTRDE NYGIPQ+ L
Sbjct: 31 MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALR 90
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI 472
GHSHF+SDVV+SSDG +ALSGSWD TLRLWDL G TTRRF HTKDVLSVAFS DNRQI
Sbjct: 91 GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQI 150
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
VSGSRDKTIKLWNTL CKYT+QD+ HS+WVSCVRFSPN +NPIIVSCGWD+ VKVW+L
Sbjct: 151 VSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLA 210
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
NCKLK NH+GH+GYLNTVTVSPDGSLCASGGKD AMLWDLN+GKHL+
Sbjct: 211 NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLY 258
>AK222488-1|BAD96208.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 varia
protein.
Length = 317
Score = 417 bits (1027), Expect = e-116
Identities = 182/228 (79%), Positives = 204/228 (89%)
Frame = +2
Query: 113 MSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLY 292
M+E + LRGTL+GHNGWVTQIAT P++PDMILS+SRDKT+I+WKLTRDE NYGIPQ+ L
Sbjct: 1 MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALR 60
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI 472
GHSHF+SDVV+SSDG +ALSGSWD TLRLWDL G TTRRF HTKDVLSVAFS DNRQI
Sbjct: 61 GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQI 120
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
VSGSRDKTIKLWNTL CKYT+QD+ HS+WVSCVRFSPN +NPIIVSCGWD+ VKVW+L
Sbjct: 121 VSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLA 180
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
NCKLK NH+GH+GYLNTVTVSPDGSLCASGGKD AMLWD N+GKHL+
Sbjct: 181 NCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDFNEGKHLY 228
>AY336089-1|AAR24619.1| 271|Homo sapiens proliferation-inducing
gene 21 protein.
Length = 271
Score = 254 bits (623), Expect = 2e-67
Identities = 111/134 (82%), Positives = 121/134 (90%)
Frame = +2
Query: 395 GKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCV 574
G TTRRF HTKDVLSVAFS DNRQIVSGSRDKTIKLWNTL CKYT+QD+ HS+WVSCV
Sbjct: 49 GTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCV 108
Query: 575 RFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDM 754
RFSPN +NPIIVSCGWD+ VKVW+L NCKLK NH+GH+GYLNTVTVSPDGSLCASGGKD
Sbjct: 109 RFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDG 168
Query: 755 XAMLWDLNDGKHLH 796
AMLWDLN+GKHL+
Sbjct: 169 QAMLWDLNEGKHLY 182
Score = 84.2 bits (199), Expect = 5e-16
Identities = 62/177 (35%), Positives = 90/177 (50%), Gaps = 4/177 (2%)
Frame = +2
Query: 269 GIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWD-LAAGKTTRRFEDHTKDVLSV 445
G +R GH+ + V SSD +SGS DKT++LW+ L K T + E H++ V V
Sbjct: 49 GTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCV 108
Query: 446 AFSVD--NRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCG 619
FS + N IVS DK +K+WN LA CK GH+ +++ V SP+ + S G
Sbjct: 109 RFSPNSSNPIIVSCGWDKLVKVWN-LANCKLKTNHIGHTGYLNTVTVSPD--GSLCASGG 165
Query: 620 WDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS-LCASGGKDMXAMLWDLNDGK 787
D +W L K + L +N + SP+ LCA+ G + +WDL +GK
Sbjct: 166 KDGQAMLWDLNEGK-HLYTLDGGDIINALCFSPNRYWLCAATGPSI--KIWDL-EGK 218
Score = 60.1 bits (139), Expect = 9e-09
Identities = 47/151 (31%), Positives = 71/151 (47%), Gaps = 2/151 (1%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLS--SDGNYALSGSWDKTLR 376
I+S SRDKT+ +W T Y + + HS ++S V S S +S WDK ++
Sbjct: 74 IVSGSRDKTIKLWN-TLGVCKYTVQDE---SHSEWVSCVRFSPNSSNPIIVSCGWDKLVK 129
Query: 377 LWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHS 556
+W+LA K HT + +V S D SG +D LW+ L E K+ DG
Sbjct: 130 VWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWD-LNEGKHLYTLDG-G 187
Query: 557 DWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 649
D ++ + FSPN + ++K+W L
Sbjct: 188 DIINALCFSPNR---YWLCAATGPSIKIWDL 215
>EF011619-1|ABK41109.1| 478|Homo sapiens CDW9/WDR51B protein.
Length = 478
Score = 122 bits (293), Expect = 2e-27
Identities = 69/216 (31%), Positives = 105/216 (48%)
Frame = +2
Query: 146 RGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVL 325
+GH +T + +P + ++S D L++W Y R GH ++ V
Sbjct: 15 KGHKAAITSLDLSPN-GKQLATASWDTFLMLWNFKPHARAY-----RYVGHKDVVTSVQF 68
Query: 326 SSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKL 505
S GN S S D+T+RLW F+ HT V SV FS D + + + S DK+IK+
Sbjct: 69 SPHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKV 128
Query: 506 WNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGH 685
W+ + ++ H+ WV C +FSP+ +IVSC D+T+K+W TN + N
Sbjct: 129 WSMYRQ-RFLYSLYRHTHWVRCAKFSPD--GRLIVSCSEDKTIKIWDTTNKQCVNNFSDS 185
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
G+ N V +P G+ AS G D +WD+ K L
Sbjct: 186 VGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLL 221
Score = 98.7 bits (235), Expect = 2e-20
Identities = 68/222 (30%), Positives = 110/222 (49%), Gaps = 6/222 (2%)
Frame = +2
Query: 149 GHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKR-----LYGHSHFIS 313
GH VT + +P + +++ S+SRD+T+ +W IP KR H+ +
Sbjct: 58 GHKDVVTSVQFSP-HGNLLASASRDRTVRLW----------IPDKRGKFSEFKAHTAPVR 106
Query: 314 DVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDK 493
V S+DG + + S DK++++W + + HT V FS D R IVS S DK
Sbjct: 107 SVDFSADGQFLATASEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDK 166
Query: 494 TIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKI 670
TIK+W+T +C D + + V F+P + I S G D+TVKVW + KL
Sbjct: 167 TIKIWDTTNKQCVNNFSDS--VGFANFVDFNP--SGTCIASAGSDQTVKVWDVRVNKLLQ 222
Query: 671 NHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
++ HSG +N ++ P G+ + D + DL +G+ ++
Sbjct: 223 HYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEGRLIY 264
Score = 98.3 bits (234), Expect = 3e-20
Identities = 59/192 (30%), Positives = 91/192 (47%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLW 382
+ ++S DK++ VW + R Y LY H+H++ S DG +S S DKT+++W
Sbjct: 117 LATASEDKSIKVWSMYRQRFLYS-----LYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIW 171
Query: 383 DLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDW 562
D + F D V F+ I S D+T+K+W+ K HS
Sbjct: 172 DTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVN-KLLQHYQVHSGG 230
Query: 563 VSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASG 742
V+C+ F P+ +++ D T+K+ L +L GH+G + TV+ S G L ASG
Sbjct: 231 VNCISFHPS--GNYLITASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASG 288
Query: 743 GKDMXAMLWDLN 778
G D +LW N
Sbjct: 289 GADTQVLLWRTN 300
Score = 52.0 bits (119), Expect = 2e-06
Identities = 34/121 (28%), Positives = 56/121 (46%), Gaps = 2/121 (1%)
Frame = +2
Query: 158 GWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDE--NNYGIPQKRLYGHSHFISDVVLSS 331
G+ + NP I S+ D+T+ VW + ++ +Y + HS ++ +
Sbjct: 187 GFANFVDFNPS-GTCIASAGSDQTVKVWDVRVNKLLQHYQV-------HSGGVNCISFHP 238
Query: 332 DGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN 511
GNY ++ S D TL++ DL G+ + HT V +V+FS SG D + LW
Sbjct: 239 SGNYLITASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLWR 298
Query: 512 T 514
T
Sbjct: 299 T 299
>BC026080-1|AAH26080.1| 478|Homo sapiens WD repeat domain 51B
protein.
Length = 478
Score = 122 bits (293), Expect = 2e-27
Identities = 69/216 (31%), Positives = 105/216 (48%)
Frame = +2
Query: 146 RGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVL 325
+GH +T + +P + ++S D L++W Y R GH ++ V
Sbjct: 15 KGHKAAITSLDLSPN-GKQLATASWDTFLMLWNFKPHARAY-----RYVGHKDVVTSVQF 68
Query: 326 SSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKL 505
S GN S S D+T+RLW F+ HT V SV FS D + + + S DK+IK+
Sbjct: 69 SPHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKV 128
Query: 506 WNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGH 685
W+ + ++ H+ WV C +FSP+ +IVSC D+T+K+W TN + N
Sbjct: 129 WSMYRQ-RFLYSLYRHTHWVRCAKFSPD--GRLIVSCSEDKTIKIWDTTNKQCVNNFSDS 185
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
G+ N V +P G+ AS G D +WD+ K L
Sbjct: 186 VGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLL 221
Score = 98.7 bits (235), Expect = 2e-20
Identities = 68/222 (30%), Positives = 110/222 (49%), Gaps = 6/222 (2%)
Frame = +2
Query: 149 GHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKR-----LYGHSHFIS 313
GH VT + +P + +++ S+SRD+T+ +W IP KR H+ +
Sbjct: 58 GHKDVVTSVQFSP-HGNLLASASRDRTVRLW----------IPDKRGKFSEFKAHTAPVR 106
Query: 314 DVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDK 493
V S+DG + + S DK++++W + + HT V FS D R IVS S DK
Sbjct: 107 SVDFSADGQFLATASEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDK 166
Query: 494 TIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKI 670
TIK+W+T +C D + + V F+P + I S G D+TVKVW + KL
Sbjct: 167 TIKIWDTTNKQCVNNFSDS--VGFANFVDFNP--SGTCIASAGSDQTVKVWDVRVNKLLQ 222
Query: 671 NHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
++ HSG +N ++ P G+ + D + DL +G+ ++
Sbjct: 223 HYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEGRLIY 264
Score = 98.3 bits (234), Expect = 3e-20
Identities = 59/192 (30%), Positives = 91/192 (47%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLW 382
+ ++S DK++ VW + R Y LY H+H++ S DG +S S DKT+++W
Sbjct: 117 LATASEDKSIKVWSMYRQRFLYS-----LYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIW 171
Query: 383 DLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDW 562
D + F D V F+ I S D+T+K+W+ K HS
Sbjct: 172 DTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVN-KLLQHYQVHSGG 230
Query: 563 VSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASG 742
V+C+ F P+ +++ D T+K+ L +L GH+G + TV+ S G L ASG
Sbjct: 231 VNCISFHPS--GNYLITASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASG 288
Query: 743 GKDMXAMLWDLN 778
G D +LW N
Sbjct: 289 GADTQVLLWRTN 300
Score = 52.0 bits (119), Expect = 2e-06
Identities = 34/121 (28%), Positives = 56/121 (46%), Gaps = 2/121 (1%)
Frame = +2
Query: 158 GWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDE--NNYGIPQKRLYGHSHFISDVVLSS 331
G+ + NP I S+ D+T+ VW + ++ +Y + HS ++ +
Sbjct: 187 GFANFVDFNPS-GTCIASAGSDQTVKVWDVRVNKLLQHYQV-------HSGGVNCISFHP 238
Query: 332 DGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN 511
GNY ++ S D TL++ DL G+ + HT V +V+FS SG D + LW
Sbjct: 239 SGNYLITASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLWR 298
Query: 512 T 514
T
Sbjct: 299 T 299
>AK074772-1|BAC11198.1| 478|Homo sapiens protein ( Homo sapiens
cDNA FLJ90291 fis, clone NT2RP1001031, weakly similar to
VEGETATIBLE INCOMPATIBILITY PROTEIN HET-E-1. ).
Length = 478
Score = 122 bits (293), Expect = 2e-27
Identities = 69/216 (31%), Positives = 105/216 (48%)
Frame = +2
Query: 146 RGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVL 325
+GH +T + +P + ++S D L++W Y R GH ++ V
Sbjct: 15 KGHKAAITSLDLSPN-GKQLATASWDTFLMLWNFKPHARAY-----RYVGHKDVVTSVQF 68
Query: 326 SSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKL 505
S GN S S D+T+RLW F+ HT V SV FS D + + + S DK+IK+
Sbjct: 69 SPHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKV 128
Query: 506 WNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGH 685
W+ + ++ H+ WV C +FSP+ +IVSC D+T+K+W TN + N
Sbjct: 129 WSMYRQ-RFLYSLYRHTHWVRCAKFSPD--GRLIVSCSEDKTIKIWDTTNKQCVNNFSDS 185
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
G+ N V +P G+ AS G D +WD+ K L
Sbjct: 186 VGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLL 221
Score = 98.7 bits (235), Expect = 2e-20
Identities = 68/222 (30%), Positives = 110/222 (49%), Gaps = 6/222 (2%)
Frame = +2
Query: 149 GHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKR-----LYGHSHFIS 313
GH VT + +P + +++ S+SRD+T+ +W IP KR H+ +
Sbjct: 58 GHKDVVTSVQFSP-HGNLLASASRDRTVRLW----------IPDKRGKFSEFKAHTAPVR 106
Query: 314 DVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDK 493
V S+DG + + S DK++++W + + HT V FS D R IVS S DK
Sbjct: 107 SVDFSADGQFLATASEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDK 166
Query: 494 TIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKI 670
TIK+W+T +C D + + V F+P + I S G D+TVKVW + KL
Sbjct: 167 TIKIWDTTNKQCVNNFSDS--VGFANFVDFNP--SGTCIASAGSDQTVKVWDVRVNKLLQ 222
Query: 671 NHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
++ HSG +N ++ P G+ + D + DL +G+ ++
Sbjct: 223 HYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEGRLIY 264
Score = 98.3 bits (234), Expect = 3e-20
Identities = 59/192 (30%), Positives = 91/192 (47%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLW 382
+ ++S DK++ VW + R Y LY H+H++ S DG +S S DKT+++W
Sbjct: 117 LATASEDKSIKVWSMYRQRFLYS-----LYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIW 171
Query: 383 DLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDW 562
D + F D V F+ I S D+T+K+W+ K HS
Sbjct: 172 DTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVN-KLLQHYQVHSGG 230
Query: 563 VSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASG 742
V+C+ F P+ +++ D T+K+ L +L GH+G + TV+ S G L ASG
Sbjct: 231 VNCISFHPS--GNYLITASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASG 288
Query: 743 GKDMXAMLWDLN 778
G D +LW N
Sbjct: 289 GADTQVLLWRTN 300
Score = 52.0 bits (119), Expect = 2e-06
Identities = 34/121 (28%), Positives = 56/121 (46%), Gaps = 2/121 (1%)
Frame = +2
Query: 158 GWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDE--NNYGIPQKRLYGHSHFISDVVLSS 331
G+ + NP I S+ D+T+ VW + ++ +Y + HS ++ +
Sbjct: 187 GFANFVDFNPS-GTCIASAGSDQTVKVWDVRVNKLLQHYQV-------HSGGVNCISFHP 238
Query: 332 DGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN 511
GNY ++ S D TL++ DL G+ + HT V +V+FS SG D + LW
Sbjct: 239 SGNYLITASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLWR 298
Query: 512 T 514
T
Sbjct: 299 T 299
>CR457279-1|CAG33560.1| 330|Homo sapiens WDR5B protein.
Length = 330
Score = 112 bits (270), Expect = 1e-24
Identities = 75/223 (33%), Positives = 117/223 (52%), Gaps = 2/223 (0%)
Frame = +2
Query: 131 LRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFI 310
L+ TL GH V+ + +P + + SSS D+ +I+W + Y +K LYGH+ I
Sbjct: 33 LKCTLVGHTEAVSSVKFSPN-GEWLASSSADRLIIIWGAY--DGKY---EKTLYGHNLEI 86
Query: 311 SDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRD 490
SDV SSD + +S S DKTL+LWD+ +GK + + H+ V F+ + I+SGS D
Sbjct: 87 SDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFD 146
Query: 491 KTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK-L 664
+T+K+W +C T+ HSD VS V F N + +IVS +D ++W + + L
Sbjct: 147 ETVKIWEVKTGKCLKTL--SAHSDPVSAVHF--NCSGSLIVSGSYDGLCRIWDAASGQCL 202
Query: 665 KINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
K + ++ V SP+G + D LWD + G+ L
Sbjct: 203 KTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCL 245
Score = 83.8 bits (198), Expect = 6e-16
Identities = 65/219 (29%), Positives = 104/219 (47%), Gaps = 6/219 (2%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDV 319
TL+GH+ +V NP ++I+S S D+T+ +W++ G K L HS +S V
Sbjct: 120 TLKGHSNYVFCCNFNPP-SNLIISGSFDETVKIWEVKT-----GKCLKTLSAHSDPVSAV 173
Query: 320 VLSSDGNYALSGSWDKTLRLWDLAAGKTTRRF-EDHTKDVLSVAFSVDNRQIVSGSRDKT 496
+ G+ +SGS+D R+WD A+G+ + +D V V FS + + I++ + D T
Sbjct: 174 HFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNT 233
Query: 497 IKLWN-TLAECKYTIQDDGHSDWVSCV--RFSPNHANPIIVSCGWDRTVKVWHLTNCKLK 667
+KLW+ + C T GH + C+ FS IVS D V +W+L ++
Sbjct: 234 LKLWDYSRGRCLKTYT--GHKNEKYCIFANFSVT-GGKWIVSGSEDNLVYIWNLQTKEIV 290
Query: 668 INHLGHSGYLNTVTVSPDGSLCASGG--KDMXAMLWDLN 778
GH+ + + P +L AS D LW N
Sbjct: 291 QKLQGHTDVVISAACHPTENLIASAALENDKTIKLWMSN 329
Score = 35.9 bits (79), Expect = 0.17
Identities = 16/46 (34%), Positives = 25/46 (54%)
Frame = +2
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKH 790
N LK +GH+ +++V SP+G AS D ++W DGK+
Sbjct: 30 NYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKY 75
>BC043494-1|AAH43494.1| 330|Homo sapiens WD repeat domain 5B
protein.
Length = 330
Score = 112 bits (270), Expect = 1e-24
Identities = 75/223 (33%), Positives = 117/223 (52%), Gaps = 2/223 (0%)
Frame = +2
Query: 131 LRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFI 310
L+ TL GH V+ + +P + + SSS D+ +I+W + Y +K LYGH+ I
Sbjct: 33 LKCTLVGHTEAVSSVKFSPN-GEWLASSSADRLIIIWGAY--DGKY---EKTLYGHNLEI 86
Query: 311 SDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRD 490
SDV SSD + +S S DKTL+LWD+ +GK + + H+ V F+ + I+SGS D
Sbjct: 87 SDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFD 146
Query: 491 KTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK-L 664
+T+K+W +C T+ HSD VS V F N + +IVS +D ++W + + L
Sbjct: 147 ETVKIWEVKTGKCLKTL--SAHSDPVSAVHF--NCSGSLIVSGSYDGLCRIWDAASGQCL 202
Query: 665 KINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
K + ++ V SP+G + D LWD + G+ L
Sbjct: 203 KTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCL 245
Score = 83.8 bits (198), Expect = 6e-16
Identities = 65/219 (29%), Positives = 104/219 (47%), Gaps = 6/219 (2%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDV 319
TL+GH+ +V NP ++I+S S D+T+ +W++ G K L HS +S V
Sbjct: 120 TLKGHSNYVFCCNFNPP-SNLIISGSFDETVKIWEVKT-----GKCLKTLSAHSDPVSAV 173
Query: 320 VLSSDGNYALSGSWDKTLRLWDLAAGKTTRRF-EDHTKDVLSVAFSVDNRQIVSGSRDKT 496
+ G+ +SGS+D R+WD A+G+ + +D V V FS + + I++ + D T
Sbjct: 174 HFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNT 233
Query: 497 IKLWN-TLAECKYTIQDDGHSDWVSCV--RFSPNHANPIIVSCGWDRTVKVWHLTNCKLK 667
+KLW+ + C T GH + C+ FS IVS D V +W+L ++
Sbjct: 234 LKLWDYSRGRCLKTYT--GHKNEKYCIFANFSVT-GGKWIVSGSEDNLVYIWNLQTKEIV 290
Query: 668 INHLGHSGYLNTVTVSPDGSLCASGG--KDMXAMLWDLN 778
GH+ + + P +L AS D LW N
Sbjct: 291 QKLQGHTDVVISAACHPTENLIASAALENDKTIKLWMSN 329
Score = 35.9 bits (79), Expect = 0.17
Identities = 16/46 (34%), Positives = 25/46 (54%)
Frame = +2
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKH 790
N LK +GH+ +++V SP+G AS D ++W DGK+
Sbjct: 30 NYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKY 75
>AK002149-1|BAA92110.1| 330|Homo sapiens protein ( Homo sapiens
cDNA FLJ11287 fis, clone PLACE1009596, weakly similar to
VEGETATIBLE INCOMPATIBILITY PROTEIN HET-E-1. ).
Length = 330
Score = 112 bits (270), Expect = 1e-24
Identities = 75/223 (33%), Positives = 117/223 (52%), Gaps = 2/223 (0%)
Frame = +2
Query: 131 LRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFI 310
L+ TL GH V+ + +P + + SSS D+ +I+W + Y +K LYGH+ I
Sbjct: 33 LKCTLVGHTEAVSSVKFSPN-GEWLASSSADRLIIIWGAY--DGKY---EKTLYGHNLEI 86
Query: 311 SDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRD 490
SDV SSD + +S S DKTL+LWD+ +GK + + H+ V F+ + I+SGS D
Sbjct: 87 SDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFD 146
Query: 491 KTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK-L 664
+T+K+W +C T+ HSD VS V F N + +IVS +D ++W + + L
Sbjct: 147 ETVKIWEVKTGKCLKTL--SAHSDPVSAVHF--NCSGSLIVSGSYDGLCRIWDAASGQCL 202
Query: 665 KINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
K + ++ V SP+G + D LWD + G+ L
Sbjct: 203 KTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCL 245
Score = 83.8 bits (198), Expect = 6e-16
Identities = 62/217 (28%), Positives = 101/217 (46%), Gaps = 4/217 (1%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDV 319
TL+GH+ +V NP ++I+S S D+T+ +W++ G K L HS +S V
Sbjct: 120 TLKGHSNYVFCCNFNPP-SNLIISGSFDETVKIWEVKT-----GKCLKTLSAHSDPVSAV 173
Query: 320 VLSSDGNYALSGSWDKTLRLWDLAAGKTTRRF-EDHTKDVLSVAFSVDNRQIVSGSRDKT 496
+ G+ +SGS+D R+WD A+G+ + +D V V FS + + I++ + D T
Sbjct: 174 HFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNT 233
Query: 497 IKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKIN 673
+KLW+ + C T + + FS IVS D V +W+L ++
Sbjct: 234 LKLWDYSRGRCLKTYTGQKNEKYCIFANFSVT-GGKWIVSGSEDNLVYIWNLQTKEIVQK 292
Query: 674 HLGHSGYLNTVTVSPDGSLCASGG--KDMXAMLWDLN 778
GH+ + + P +L AS D LW N
Sbjct: 293 LQGHTDVVISAACHPTENLIASAALENDKTIKLWMSN 329
Score = 35.9 bits (79), Expect = 0.17
Identities = 16/46 (34%), Positives = 25/46 (54%)
Frame = +2
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKH 790
N LK +GH+ +++V SP+G AS D ++W DGK+
Sbjct: 30 NYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKY 75
>BX649632-1|CAI18774.1| 334|Homo sapiens WD repeat domain 5
protein.
Length = 334
Score = 108 bits (260), Expect = 2e-23
Identities = 73/223 (32%), Positives = 114/223 (51%), Gaps = 2/223 (0%)
Frame = +2
Query: 131 LRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFI 310
L+ TL GH V+ + +P + + SSS DK + +W G +K + GH I
Sbjct: 37 LKFTLAGHTKAVSSVKFSPN-GEWLASSSADKLIKIWGAYD-----GKFEKTISGHKLGI 90
Query: 311 SDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRD 490
SDV SSD N +S S DKTL++WD+++GK + + H+ V F+ + IVSGS D
Sbjct: 91 SDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFD 150
Query: 491 KTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK-L 664
+++++W+ +C T+ HSD VS V F N +IVS +D ++W + + L
Sbjct: 151 ESVRIWDVKTGKCLKTL--PAHSDPVSAVHF--NRDGSLIVSSSYDGLCRIWDTASGQCL 206
Query: 665 KINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
K + ++ V SP+G + D LWD + GK L
Sbjct: 207 KTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCL 249
Score = 80.6 bits (190), Expect = 6e-15
Identities = 62/216 (28%), Positives = 104/216 (48%), Gaps = 6/216 (2%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDV 319
TL+GH+ +V NP+ ++I+S S D+++ +W + G K L HS +S V
Sbjct: 124 TLKGHSNYVFCCNFNPQ-SNLIVSGSFDESVRIWDVKT-----GKCLKTLPAHSDPVSAV 177
Query: 320 VLSSDGNYALSGSWDKTLRLWDLAAGKTTRRF-EDHTKDVLSVAFSVDNRQIVSGSRDKT 496
+ DG+ +S S+D R+WD A+G+ + +D V V FS + + I++ + D T
Sbjct: 178 HFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNT 237
Query: 497 IKLWN-TLAECKYTIQDDGHSDWVSCV--RFSPNHANPIIVSCGWDRTVKVWHLTNCKLK 667
+KLW+ + +C T GH + C+ FS IVS D V +W+L ++
Sbjct: 238 LKLWDYSKGKCLKTYT--GHKNEKYCIFANFSVT-GGKWIVSGSEDNLVYIWNLQTKEIV 294
Query: 668 INHLGHSGYLNTVTVSPDGSLCASGG--KDMXAMLW 769
GH+ + + P ++ AS D LW
Sbjct: 295 QKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 330
Score = 62.5 bits (145), Expect = 2e-09
Identities = 54/180 (30%), Positives = 83/180 (46%), Gaps = 5/180 (2%)
Frame = +2
Query: 119 ETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGH 298
+T K TL H+ V+ + N + +I+SSS D +W + G K L
Sbjct: 159 KTGKCLKTLPAHSDPVSAVHFN-RDGSLIVSSSYDGLCRIW-----DTASGQCLKTLIDD 212
Query: 299 SHF-ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDH--TKDVLSVAFSV-DNR 466
+ +S V S +G Y L+ + D TL+LWD + GK + + H K + FSV +
Sbjct: 213 DNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGK 272
Query: 467 QIVSGSRDKTIKLWNTLAECKYTIQD-DGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVW 643
IVSGS D + +WN + K +Q GH+D V P + D+T+K+W
Sbjct: 273 WIVSGSEDNLVYIWN--LQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 330
Score = 44.4 bits (100), Expect = 5e-04
Identities = 34/120 (28%), Positives = 58/120 (48%), Gaps = 5/120 (4%)
Frame = +2
Query: 170 QIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLS---SDGN 340
+ + N KY IL+++ D TL +W ++ G K GH + + + + G
Sbjct: 221 KFSPNGKY---ILAATLDNTLKLWDYSK-----GKCLKTYTGHKNEKYCIFANFSVTGGK 272
Query: 341 YALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGS--RDKTIKLWNT 514
+ +SGS D + +W+L + ++ + HT V+S A I S + DKTIKLW +
Sbjct: 273 WIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKS 332
Score = 33.9 bits (74), Expect = 0.68
Identities = 16/45 (35%), Positives = 22/45 (48%)
Frame = +2
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGK 787
N LK GH+ +++V SP+G AS D +W DGK
Sbjct: 34 NYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGK 78
>BC001635-1|AAH01635.1| 334|Homo sapiens WD repeat domain 5
protein.
Length = 334
Score = 108 bits (260), Expect = 2e-23
Identities = 73/223 (32%), Positives = 114/223 (51%), Gaps = 2/223 (0%)
Frame = +2
Query: 131 LRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFI 310
L+ TL GH V+ + +P + + SSS DK + +W G +K + GH I
Sbjct: 37 LKFTLAGHTKAVSSVKFSPN-GEWLASSSADKLIKIWGAYD-----GKFEKTISGHKLGI 90
Query: 311 SDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRD 490
SDV SSD N +S S DKTL++WD+++GK + + H+ V F+ + IVSGS D
Sbjct: 91 SDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFD 150
Query: 491 KTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK-L 664
+++++W+ +C T+ HSD VS V F N +IVS +D ++W + + L
Sbjct: 151 ESVRIWDVKTGKCLKTL--PAHSDPVSAVHF--NRDGSLIVSSSYDGLCRIWDTASGQCL 206
Query: 665 KINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
K + ++ V SP+G + D LWD + GK L
Sbjct: 207 KTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCL 249
Score = 80.6 bits (190), Expect = 6e-15
Identities = 62/216 (28%), Positives = 104/216 (48%), Gaps = 6/216 (2%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDV 319
TL+GH+ +V NP+ ++I+S S D+++ +W + G K L HS +S V
Sbjct: 124 TLKGHSNYVFCCNFNPQ-SNLIVSGSFDESVRIWDVKT-----GKCLKTLPAHSDPVSAV 177
Query: 320 VLSSDGNYALSGSWDKTLRLWDLAAGKTTRRF-EDHTKDVLSVAFSVDNRQIVSGSRDKT 496
+ DG+ +S S+D R+WD A+G+ + +D V V FS + + I++ + D T
Sbjct: 178 HFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNT 237
Query: 497 IKLWN-TLAECKYTIQDDGHSDWVSCV--RFSPNHANPIIVSCGWDRTVKVWHLTNCKLK 667
+KLW+ + +C T GH + C+ FS IVS D V +W+L ++
Sbjct: 238 LKLWDYSKGKCLKTYT--GHKNEKYCIFANFSVT-GGKWIVSGSEDNLVYIWNLQTKEIV 294
Query: 668 INHLGHSGYLNTVTVSPDGSLCASGG--KDMXAMLW 769
GH+ + + P ++ AS D LW
Sbjct: 295 QKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 330
Score = 62.5 bits (145), Expect = 2e-09
Identities = 54/180 (30%), Positives = 83/180 (46%), Gaps = 5/180 (2%)
Frame = +2
Query: 119 ETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGH 298
+T K TL H+ V+ + N + +I+SSS D +W + G K L
Sbjct: 159 KTGKCLKTLPAHSDPVSAVHFN-RDGSLIVSSSYDGLCRIW-----DTASGQCLKTLIDD 212
Query: 299 SHF-ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDH--TKDVLSVAFSV-DNR 466
+ +S V S +G Y L+ + D TL+LWD + GK + + H K + FSV +
Sbjct: 213 DNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGK 272
Query: 467 QIVSGSRDKTIKLWNTLAECKYTIQD-DGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVW 643
IVSGS D + +WN + K +Q GH+D V P + D+T+K+W
Sbjct: 273 WIVSGSEDNLVYIWN--LQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 330
Score = 44.4 bits (100), Expect = 5e-04
Identities = 34/120 (28%), Positives = 58/120 (48%), Gaps = 5/120 (4%)
Frame = +2
Query: 170 QIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLS---SDGN 340
+ + N KY IL+++ D TL +W ++ G K GH + + + + G
Sbjct: 221 KFSPNGKY---ILAATLDNTLKLWDYSK-----GKCLKTYTGHKNEKYCIFANFSVTGGK 272
Query: 341 YALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGS--RDKTIKLWNT 514
+ +SGS D + +W+L + ++ + HT V+S A I S + DKTIKLW +
Sbjct: 273 WIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKS 332
Score = 33.9 bits (74), Expect = 0.68
Identities = 16/45 (35%), Positives = 22/45 (48%)
Frame = +2
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGK 787
N LK GH+ +++V SP+G AS D +W DGK
Sbjct: 34 NYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGK 78
>AK000552-1|BAA91248.1| 334|Homo sapiens protein ( Homo sapiens
cDNA FLJ20545 fis, clone KAT11476. ).
Length = 334
Score = 108 bits (260), Expect = 2e-23
Identities = 73/223 (32%), Positives = 114/223 (51%), Gaps = 2/223 (0%)
Frame = +2
Query: 131 LRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFI 310
L+ TL GH V+ + +P + + SSS DK + +W G +K + GH I
Sbjct: 37 LKFTLAGHTKAVSSVKFSPN-GEWLASSSADKLIKIWGAYD-----GKFEKTISGHKLGI 90
Query: 311 SDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRD 490
SDV SSD N +S S DKTL++WD+++GK + + H+ V F+ + IVSGS D
Sbjct: 91 SDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFD 150
Query: 491 KTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK-L 664
+++++W+ +C T+ HSD VS V F N +IVS +D ++W + + L
Sbjct: 151 ESVRIWDVKTGKCLKTL--PAHSDPVSAVHF--NRDGSLIVSSSYDGLCRIWDTASGQCL 206
Query: 665 KINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
K + ++ V SP+G + D LWD + GK L
Sbjct: 207 KTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCL 249
Score = 80.6 bits (190), Expect = 6e-15
Identities = 62/216 (28%), Positives = 104/216 (48%), Gaps = 6/216 (2%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDV 319
TL+GH+ +V NP+ ++I+S S D+++ +W + G K L HS +S V
Sbjct: 124 TLKGHSNYVFCCNFNPQ-SNLIVSGSFDESVRIWDVKT-----GKCLKTLPAHSDPVSAV 177
Query: 320 VLSSDGNYALSGSWDKTLRLWDLAAGKTTRRF-EDHTKDVLSVAFSVDNRQIVSGSRDKT 496
+ DG+ +S S+D R+WD A+G+ + +D V V FS + + I++ + D T
Sbjct: 178 HFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNT 237
Query: 497 IKLWN-TLAECKYTIQDDGHSDWVSCV--RFSPNHANPIIVSCGWDRTVKVWHLTNCKLK 667
+KLW+ + +C T GH + C+ FS IVS D V +W+L ++
Sbjct: 238 LKLWDYSKGKCLKTYT--GHKNEKYCIFANFSVT-GGKWIVSGSEDNLVYIWNLQTKEIV 294
Query: 668 INHLGHSGYLNTVTVSPDGSLCASGG--KDMXAMLW 769
GH+ + + P ++ AS D LW
Sbjct: 295 QKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 330
Score = 62.5 bits (145), Expect = 2e-09
Identities = 54/180 (30%), Positives = 83/180 (46%), Gaps = 5/180 (2%)
Frame = +2
Query: 119 ETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGH 298
+T K TL H+ V+ + N + +I+SSS D +W + G K L
Sbjct: 159 KTGKCLKTLPAHSDPVSAVHFN-RDGSLIVSSSYDGLCRIW-----DTASGQCLKTLIDD 212
Query: 299 SHF-ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDH--TKDVLSVAFSV-DNR 466
+ +S V S +G Y L+ + D TL+LWD + GK + + H K + FSV +
Sbjct: 213 DNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGK 272
Query: 467 QIVSGSRDKTIKLWNTLAECKYTIQD-DGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVW 643
IVSGS D + +WN + K +Q GH+D V P + D+T+K+W
Sbjct: 273 WIVSGSEDNLVYIWN--LQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 330
Score = 44.4 bits (100), Expect = 5e-04
Identities = 34/120 (28%), Positives = 58/120 (48%), Gaps = 5/120 (4%)
Frame = +2
Query: 170 QIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLS---SDGN 340
+ + N KY IL+++ D TL +W ++ G K GH + + + + G
Sbjct: 221 KFSPNGKY---ILAATLDNTLKLWDYSK-----GKCLKTYTGHKNEKYCIFANFSVTGGK 272
Query: 341 YALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGS--RDKTIKLWNT 514
+ +SGS D + +W+L + ++ + HT V+S A I S + DKTIKLW +
Sbjct: 273 WIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKS 332
Score = 33.9 bits (74), Expect = 0.68
Identities = 16/45 (35%), Positives = 22/45 (48%)
Frame = +2
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGK 787
N LK GH+ +++V SP+G AS D +W DGK
Sbjct: 34 NYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGK 78
>AJ011376-1|CAB66159.1| 362|Homo sapiens hypothetical protein
protein.
Length = 362
Score = 108 bits (260), Expect = 2e-23
Identities = 73/223 (32%), Positives = 114/223 (51%), Gaps = 2/223 (0%)
Frame = +2
Query: 131 LRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFI 310
L+ TL GH V+ + +P + + SSS DK + +W G +K + GH I
Sbjct: 65 LKFTLAGHTKAVSSVKFSPN-GEWLASSSADKLIKIWGAYD-----GKFEKTISGHKLGI 118
Query: 311 SDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRD 490
SDV SSD N +S S DKTL++WD+++GK + + H+ V F+ + IVSGS D
Sbjct: 119 SDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFD 178
Query: 491 KTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK-L 664
+++++W+ +C T+ HSD VS V F N +IVS +D ++W + + L
Sbjct: 179 ESVRIWDVKTGKCLKTL--PAHSDPVSAVHF--NRDGSLIVSSSYDGLCRIWDTASGQCL 234
Query: 665 KINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
K + ++ V SP+G + D LWD + GK L
Sbjct: 235 KTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCL 277
Score = 80.6 bits (190), Expect = 6e-15
Identities = 62/216 (28%), Positives = 104/216 (48%), Gaps = 6/216 (2%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDV 319
TL+GH+ +V NP+ ++I+S S D+++ +W + G K L HS +S V
Sbjct: 152 TLKGHSNYVFCCNFNPQ-SNLIVSGSFDESVRIWDVKT-----GKCLKTLPAHSDPVSAV 205
Query: 320 VLSSDGNYALSGSWDKTLRLWDLAAGKTTRRF-EDHTKDVLSVAFSVDNRQIVSGSRDKT 496
+ DG+ +S S+D R+WD A+G+ + +D V V FS + + I++ + D T
Sbjct: 206 HFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNT 265
Query: 497 IKLWN-TLAECKYTIQDDGHSDWVSCV--RFSPNHANPIIVSCGWDRTVKVWHLTNCKLK 667
+KLW+ + +C T GH + C+ FS IVS D V +W+L ++
Sbjct: 266 LKLWDYSKGKCLKTYT--GHKNEKYCIFANFSVT-GGKWIVSGSEDNLVYIWNLQTKEIV 322
Query: 668 INHLGHSGYLNTVTVSPDGSLCASGG--KDMXAMLW 769
GH+ + + P ++ AS D LW
Sbjct: 323 QKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 358
Score = 62.5 bits (145), Expect = 2e-09
Identities = 54/180 (30%), Positives = 83/180 (46%), Gaps = 5/180 (2%)
Frame = +2
Query: 119 ETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGH 298
+T K TL H+ V+ + N + +I+SSS D +W + G K L
Sbjct: 187 KTGKCLKTLPAHSDPVSAVHFN-RDGSLIVSSSYDGLCRIW-----DTASGQCLKTLIDD 240
Query: 299 SHF-ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDH--TKDVLSVAFSV-DNR 466
+ +S V S +G Y L+ + D TL+LWD + GK + + H K + FSV +
Sbjct: 241 DNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGK 300
Query: 467 QIVSGSRDKTIKLWNTLAECKYTIQD-DGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVW 643
IVSGS D + +WN + K +Q GH+D V P + D+T+K+W
Sbjct: 301 WIVSGSEDNLVYIWN--LQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 358
Score = 44.4 bits (100), Expect = 5e-04
Identities = 34/120 (28%), Positives = 58/120 (48%), Gaps = 5/120 (4%)
Frame = +2
Query: 170 QIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLS---SDGN 340
+ + N KY IL+++ D TL +W ++ G K GH + + + + G
Sbjct: 249 KFSPNGKY---ILAATLDNTLKLWDYSK-----GKCLKTYTGHKNEKYCIFANFSVTGGK 300
Query: 341 YALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGS--RDKTIKLWNT 514
+ +SGS D + +W+L + ++ + HT V+S A I S + DKTIKLW +
Sbjct: 301 WIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKS 360
Score = 33.9 bits (74), Expect = 0.68
Identities = 16/45 (35%), Positives = 22/45 (48%)
Frame = +2
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGK 787
N LK GH+ +++V SP+G AS D +W DGK
Sbjct: 62 NYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGK 106
>BC127949-1|AAI27950.1| 314|Homo sapiens WD repeat domain 38
protein.
Length = 314
Score = 106 bits (255), Expect = 8e-23
Identities = 66/219 (30%), Positives = 101/219 (46%), Gaps = 2/219 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH G V +P + S+S D T+ +W + R + + L GH + V
Sbjct: 59 LGGHTGPVKFCRFSPD-GHLFASASCDCTVRLWDVARAKC-----LRVLKGHQRSVETVS 112
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
S D SG WDK + LWD+ +G+ R H + S FS + +GS D T++
Sbjct: 113 FSPDSRQLASGGWDKRVMLWDVQSGQMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVR 172
Query: 503 LWNTLAECKYTIQD--DGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINH 676
+W+ +GHS +SC+ +S A+ ++ S WD+T+ +W T L I
Sbjct: 173 IWDLRMVTPAVSHQALEGHSGNISCLCYS---ASGLLASGSWDKTIHIWKPTTSSLLIQL 229
Query: 677 LGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
GH ++ ++ SPD AS G +WD N GK L
Sbjct: 230 KGHVTWVKSIAFSPDELWLASAGYSRMVKVWDCNTGKCL 268
Score = 99.5 bits (237), Expect = 1e-20
Identities = 70/209 (33%), Positives = 100/209 (47%), Gaps = 3/209 (1%)
Frame = +2
Query: 152 HNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSS 331
H G V A +P M+L+ S D + W E G RL GH+ + S
Sbjct: 20 HGGEVNSSAFSPD-GQMLLTGSEDGCVYGW-----ETRSGQLLWRLGGHTGPVKFCRFSP 73
Query: 332 DGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN 511
DG+ S S D T+RLWD+A K R + H + V +V+FS D+RQ+ SG DK + LW+
Sbjct: 74 DGHLFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWD 133
Query: 512 TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL---G 682
+ + GH D + FSP N + + WD TV++W L ++H G
Sbjct: 134 VQSGQMLRLL-VGHRDSIQSSDFSPT-VN-CLATGSWDSTVRIWDLRMVTPAVSHQALEG 190
Query: 683 HSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
HSG ++ + S G L ASG D +W
Sbjct: 191 HSGNISCLCYSASG-LLASGSWDKTIHIW 218
Score = 88.6 bits (210), Expect = 2e-17
Identities = 61/206 (29%), Positives = 90/206 (43%), Gaps = 3/206 (1%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L+GH V ++ +P + S DK +++W + G + L GH I
Sbjct: 101 LKGHQRSVETVSFSPD-SRQLASGGWDKRVMLWDVQS-----GQMLRLLVGHRDSIQSSD 154
Query: 323 LSSDGNYALSGSWDKTLRLWDL---AAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDK 493
S N +GSWD T+R+WDL + + E H+ ++ + +S + SGS DK
Sbjct: 155 FSPTVNCLATGSWDSTVRIWDLRMVTPAVSHQALEGHSGNISCLCYSASGL-LASGSWDK 213
Query: 494 TIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKIN 673
TI +W IQ GH WV + FSP+ + S G+ R VKVW K
Sbjct: 214 TIHIWKPTTS-SLLIQLKGHVTWVKSIAFSPDEL--WLASAGYSRMVKVWDCNTGKCLET 270
Query: 674 HLGHSGYLNTVTVSPDGSLCASGGKD 751
G +T +PDG + SG D
Sbjct: 271 LKGVLDVAHTCAFTPDGKILVSGAAD 296
Score = 72.9 bits (171), Expect = 1e-12
Identities = 45/134 (33%), Positives = 66/134 (49%)
Frame = +2
Query: 392 AGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSC 571
A + + F H +V S AFS D + +++GS D + W T + + + GH+ V
Sbjct: 10 AVRRVKFFGQHGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSG-QLLWRLGGHTGPVKF 68
Query: 572 VRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKD 751
RFSP+ + S D TV++W + K GH + TV+ SPD ASGG D
Sbjct: 69 CRFSPD--GHLFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWD 126
Query: 752 MXAMLWDLNDGKHL 793
MLWD+ G+ L
Sbjct: 127 KRVMLWDVQSGQML 140
Score = 49.6 bits (113), Expect = 1e-05
Identities = 30/118 (25%), Positives = 56/118 (47%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH+G ++ + + ++ S S DKT+ +WK T +L GH ++ +
Sbjct: 188 LEGHSGNISCLCYSAS--GLLASGSWDKTIHIWKPTTSSLLI-----QLKGHVTWVKSIA 240
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKT 496
S D + S + + +++WD GK + + AF+ D + +VSG+ D+T
Sbjct: 241 FSPDELWLASAGYSRMVKVWDCNTGKCLETLKGVLDVAHTCAFTPDGKILVSGAADQT 298
>U72342-1|AAC51111.1| 410|Homo sapiens platelet activating factor
acetylhydrolase, brain isoform, 45 kDa subunit protein.
Length = 410
Score = 105 bits (253), Expect = 1e-22
Identities = 64/196 (32%), Positives = 97/196 (49%), Gaps = 1/196 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH VT++ +P + M+ S+S D T+ VW + G ++ L GH+ + D+
Sbjct: 104 LSGHRSPVTRVIFHPVFSVMV-SASEDATIKVW-----DYETGDFERTLKGHTDSVQDIS 157
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
G S S D T++LWD + R H +V SVA + IVS SRDKTIK
Sbjct: 158 FDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIK 217
Query: 503 LWNTLAECKYTIQD-DGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
+W + Y ++ GH +WV VR PN +I SC D+TV+VW + + K
Sbjct: 218 MWE--VQTGYCVKTFTGHREWVRMVR--PNQDGTLIASCSNDQTVRVWVVATKECKAELR 273
Query: 680 GHSGYLNTVTVSPDGS 727
H + ++ +P+ S
Sbjct: 274 EHEHVVECISWAPESS 289
Score = 84.2 bits (199), Expect = 5e-16
Identities = 53/167 (31%), Positives = 79/167 (47%), Gaps = 2/167 (1%)
Frame = +2
Query: 275 PQK-RLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAF 451
P+K L GH ++ V+ + +S S D T+++WD G R + HT V ++F
Sbjct: 99 PEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISF 158
Query: 452 SVDNRQIVSGSRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR 628
+ + S S D TIKLW+ EC T+ GH VS V PN + IVS D+
Sbjct: 159 DHSGKLLASCSADMTIKLWDFQGFECIRTMH--GHDHNVSSVAIMPNGDH--IVSASRDK 214
Query: 629 TVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
T+K+W + GH ++ V + DG+L AS D +W
Sbjct: 215 TIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVW 261
Score = 82.6 bits (195), Expect = 1e-15
Identities = 61/232 (26%), Positives = 108/232 (46%), Gaps = 21/232 (9%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDV 319
T+ GH+ V+ +A P D I+S+SRDKT+ +W++ + Y + K GH ++ V
Sbjct: 187 TMHGHDHNVSSVAIMPN-GDHIVSASRDKTIKMWEV---QTGYCV--KTFTGHREWVRMV 240
Query: 320 VLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQ---------- 469
+ DG S S D+T+R+W +A + +H V ++++ ++
Sbjct: 241 RPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSE 300
Query: 470 ----------IVSGSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSC 616
++SGSRDKTIK+W+ + C T+ GH +WV V F + I+SC
Sbjct: 301 TKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLV--GHDNWVRGVLF--HSGGKFILSC 356
Query: 617 GWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
D+T++VW N + H ++ ++ +G D +W+
Sbjct: 357 ADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
Score = 61.3 bits (142), Expect = 4e-09
Identities = 34/122 (27%), Positives = 59/122 (48%), Gaps = 1/122 (0%)
Frame = +2
Query: 422 HTKDVLSVAFSVDNRQIVSGSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHAN 598
H V V F +VS S D TIK+W+ + + T++ GH+D V + F +H+
Sbjct: 107 HRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLK--GHTDSVQDISF--DHSG 162
Query: 599 PIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLN 778
++ SC D T+K+W + GH +++V + P+G S +D +W++
Sbjct: 163 KLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQ 222
Query: 779 DG 784
G
Sbjct: 223 TG 224
>L13386-1|AAA02881.1| 410|Homo sapiens Miller-Dieker lissencephaly
protein protein.
Length = 410
Score = 105 bits (253), Expect = 1e-22
Identities = 64/196 (32%), Positives = 97/196 (49%), Gaps = 1/196 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH VT++ +P + M+ S+S D T+ VW + G ++ L GH+ + D+
Sbjct: 104 LSGHRSPVTRVIFHPVFSVMV-SASEDATIKVW-----DYETGDFERTLKGHTDSVQDIS 157
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
G S S D T++LWD + R H +V SVA + IVS SRDKTIK
Sbjct: 158 FDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIK 217
Query: 503 LWNTLAECKYTIQD-DGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
+W + Y ++ GH +WV VR PN +I SC D+TV+VW + + K
Sbjct: 218 MWE--VQTGYCVKTFTGHREWVRMVR--PNQDGTLIASCSNDQTVRVWVVATKECKAELR 273
Query: 680 GHSGYLNTVTVSPDGS 727
H + ++ +P+ S
Sbjct: 274 EHEHVVECISWAPESS 289
Score = 84.2 bits (199), Expect = 5e-16
Identities = 53/167 (31%), Positives = 79/167 (47%), Gaps = 2/167 (1%)
Frame = +2
Query: 275 PQK-RLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAF 451
P+K L GH ++ V+ + +S S D T+++WD G R + HT V ++F
Sbjct: 99 PEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISF 158
Query: 452 SVDNRQIVSGSRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR 628
+ + S S D TIKLW+ EC T+ GH VS V PN + IVS D+
Sbjct: 159 DHSGKLLASCSADMTIKLWDFQGFECIRTMH--GHDHNVSSVAIMPNGDH--IVSASRDK 214
Query: 629 TVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
T+K+W + GH ++ V + DG+L AS D +W
Sbjct: 215 TIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVW 261
Score = 82.6 bits (195), Expect = 1e-15
Identities = 61/232 (26%), Positives = 108/232 (46%), Gaps = 21/232 (9%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDV 319
T+ GH+ V+ +A P D I+S+SRDKT+ +W++ + Y + K GH ++ V
Sbjct: 187 TMHGHDHNVSSVAIMPN-GDHIVSASRDKTIKMWEV---QTGYCV--KTFTGHREWVRMV 240
Query: 320 VLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQ---------- 469
+ DG S S D+T+R+W +A + +H V ++++ ++
Sbjct: 241 RPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSE 300
Query: 470 ----------IVSGSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSC 616
++SGSRDKTIK+W+ + C T+ GH +WV V F + I+SC
Sbjct: 301 TKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLV--GHDNWVRGVLF--HSGGKFILSC 356
Query: 617 GWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
D+T++VW N + H ++ ++ +G D +W+
Sbjct: 357 ADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
Score = 61.3 bits (142), Expect = 4e-09
Identities = 34/122 (27%), Positives = 59/122 (48%), Gaps = 1/122 (0%)
Frame = +2
Query: 422 HTKDVLSVAFSVDNRQIVSGSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHAN 598
H V V F +VS S D TIK+W+ + + T++ GH+D V + F +H+
Sbjct: 107 HRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLK--GHTDSVQDISF--DHSG 162
Query: 599 PIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLN 778
++ SC D T+K+W + GH +++V + P+G S +D +W++
Sbjct: 163 KLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQ 222
Query: 779 DG 784
G
Sbjct: 223 TG 224
>L13385-1|AAA02880.1| 410|Homo sapiens Miller-Dieker lissencephaly
protein protein.
Length = 410
Score = 105 bits (253), Expect = 1e-22
Identities = 64/196 (32%), Positives = 97/196 (49%), Gaps = 1/196 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH VT++ +P + M+ S+S D T+ VW + G ++ L GH+ + D+
Sbjct: 104 LSGHRSPVTRVIFHPVFSVMV-SASEDATIKVW-----DYETGDFERTLKGHTDSVQDIS 157
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
G S S D T++LWD + R H +V SVA + IVS SRDKTIK
Sbjct: 158 FDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIK 217
Query: 503 LWNTLAECKYTIQD-DGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
+W + Y ++ GH +WV VR PN +I SC D+TV+VW + + K
Sbjct: 218 MWE--VQTGYCVKTFTGHREWVRMVR--PNQDGTLIASCSNDQTVRVWVVATKECKAELR 273
Query: 680 GHSGYLNTVTVSPDGS 727
H + ++ +P+ S
Sbjct: 274 EHEHVVECISWAPESS 289
Score = 84.2 bits (199), Expect = 5e-16
Identities = 53/167 (31%), Positives = 79/167 (47%), Gaps = 2/167 (1%)
Frame = +2
Query: 275 PQK-RLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAF 451
P+K L GH ++ V+ + +S S D T+++WD G R + HT V ++F
Sbjct: 99 PEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISF 158
Query: 452 SVDNRQIVSGSRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR 628
+ + S S D TIKLW+ EC T+ GH VS V PN + IVS D+
Sbjct: 159 DHSGKLLASCSADMTIKLWDFQGFECIRTMH--GHDHNVSSVAIMPNGDH--IVSASRDK 214
Query: 629 TVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
T+K+W + GH ++ V + DG+L AS D +W
Sbjct: 215 TIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVW 261
Score = 82.6 bits (195), Expect = 1e-15
Identities = 61/232 (26%), Positives = 108/232 (46%), Gaps = 21/232 (9%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDV 319
T+ GH+ V+ +A P D I+S+SRDKT+ +W++ + Y + K GH ++ V
Sbjct: 187 TMHGHDHNVSSVAIMPN-GDHIVSASRDKTIKMWEV---QTGYCV--KTFTGHREWVRMV 240
Query: 320 VLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQ---------- 469
+ DG S S D+T+R+W +A + +H V ++++ ++
Sbjct: 241 RPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSE 300
Query: 470 ----------IVSGSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSC 616
++SGSRDKTIK+W+ + C T+ GH +WV V F + I+SC
Sbjct: 301 TKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLV--GHDNWVRGVLF--HSGGKFILSC 356
Query: 617 GWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
D+T++VW N + H ++ ++ +G D +W+
Sbjct: 357 ADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
Score = 61.3 bits (142), Expect = 4e-09
Identities = 34/122 (27%), Positives = 59/122 (48%), Gaps = 1/122 (0%)
Frame = +2
Query: 422 HTKDVLSVAFSVDNRQIVSGSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHAN 598
H V V F +VS S D TIK+W+ + + T++ GH+D V + F +H+
Sbjct: 107 HRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLK--GHTDSVQDISF--DHSG 162
Query: 599 PIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLN 778
++ SC D T+K+W + GH +++V + P+G S +D +W++
Sbjct: 163 KLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQ 222
Query: 779 DG 784
G
Sbjct: 223 TG 224
>BC064638-1|AAH64638.1| 410|Homo sapiens platelet-activating factor
acetylhydrolase, isoform Ib, alpha subunit 45kDa
protein.
Length = 410
Score = 105 bits (253), Expect = 1e-22
Identities = 64/196 (32%), Positives = 97/196 (49%), Gaps = 1/196 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH VT++ +P + M+ S+S D T+ VW + G ++ L GH+ + D+
Sbjct: 104 LSGHRSPVTRVIFHPVFSVMV-SASEDATIKVW-----DYETGDFERTLKGHTDSVQDIS 157
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
G S S D T++LWD + R H +V SVA + IVS SRDKTIK
Sbjct: 158 FDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIK 217
Query: 503 LWNTLAECKYTIQD-DGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
+W + Y ++ GH +WV VR PN +I SC D+TV+VW + + K
Sbjct: 218 MWE--VQTGYCVKTFTGHREWVRMVR--PNQDGTLIASCSNDQTVRVWVVATKECKAELR 273
Query: 680 GHSGYLNTVTVSPDGS 727
H + ++ +P+ S
Sbjct: 274 EHEHVVECISWAPESS 289
Score = 84.2 bits (199), Expect = 5e-16
Identities = 53/167 (31%), Positives = 79/167 (47%), Gaps = 2/167 (1%)
Frame = +2
Query: 275 PQK-RLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAF 451
P+K L GH ++ V+ + +S S D T+++WD G R + HT V ++F
Sbjct: 99 PEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISF 158
Query: 452 SVDNRQIVSGSRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR 628
+ + S S D TIKLW+ EC T+ GH VS V PN + IVS D+
Sbjct: 159 DHSGKLLASCSADMTIKLWDFQGFECIRTMH--GHDHNVSSVAIMPNGDH--IVSASRDK 214
Query: 629 TVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
T+K+W + GH ++ V + DG+L AS D +W
Sbjct: 215 TIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVW 261
Score = 82.6 bits (195), Expect = 1e-15
Identities = 61/232 (26%), Positives = 108/232 (46%), Gaps = 21/232 (9%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDV 319
T+ GH+ V+ +A P D I+S+SRDKT+ +W++ + Y + K GH ++ V
Sbjct: 187 TMHGHDHNVSSVAIMPN-GDHIVSASRDKTIKMWEV---QTGYCV--KTFTGHREWVRMV 240
Query: 320 VLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQ---------- 469
+ DG S S D+T+R+W +A + +H V ++++ ++
Sbjct: 241 RPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSE 300
Query: 470 ----------IVSGSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSC 616
++SGSRDKTIK+W+ + C T+ GH +WV V F + I+SC
Sbjct: 301 TKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLV--GHDNWVRGVLF--HSGGKFILSC 356
Query: 617 GWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
D+T++VW N + H ++ ++ +G D +W+
Sbjct: 357 ADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
Score = 61.3 bits (142), Expect = 4e-09
Identities = 34/122 (27%), Positives = 59/122 (48%), Gaps = 1/122 (0%)
Frame = +2
Query: 422 HTKDVLSVAFSVDNRQIVSGSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHAN 598
H V V F +VS S D TIK+W+ + + T++ GH+D V + F +H+
Sbjct: 107 HRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLK--GHTDSVQDISF--DHSG 162
Query: 599 PIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLN 778
++ SC D T+K+W + GH +++V + P+G S +D +W++
Sbjct: 163 KLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQ 222
Query: 779 DG 784
G
Sbjct: 223 TG 224
>AF400434-1|AAK92483.1| 410|Homo sapiens platelet-activating factor
acetyl hydrolase isoform Ib alpha subunit protein.
Length = 410
Score = 105 bits (253), Expect = 1e-22
Identities = 64/196 (32%), Positives = 97/196 (49%), Gaps = 1/196 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH VT++ +P + M+ S+S D T+ VW + G ++ L GH+ + D+
Sbjct: 104 LSGHRSPVTRVIFHPVFSVMV-SASEDATIKVW-----DYETGDFERTLKGHTDSVQDIS 157
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
G S S D T++LWD + R H +V SVA + IVS SRDKTIK
Sbjct: 158 FDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIK 217
Query: 503 LWNTLAECKYTIQD-DGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
+W + Y ++ GH +WV VR PN +I SC D+TV+VW + + K
Sbjct: 218 MWE--VQTGYCVKTFTGHREWVRMVR--PNQDGTLIASCSNDQTVRVWVVATKECKAELR 273
Query: 680 GHSGYLNTVTVSPDGS 727
H + ++ +P+ S
Sbjct: 274 EHEHVVECISWAPESS 289
Score = 84.2 bits (199), Expect = 5e-16
Identities = 53/167 (31%), Positives = 79/167 (47%), Gaps = 2/167 (1%)
Frame = +2
Query: 275 PQK-RLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAF 451
P+K L GH ++ V+ + +S S D T+++WD G R + HT V ++F
Sbjct: 99 PEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISF 158
Query: 452 SVDNRQIVSGSRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR 628
+ + S S D TIKLW+ EC T+ GH VS V PN + IVS D+
Sbjct: 159 DHSGKLLASCSADMTIKLWDFQGFECIRTMH--GHDHNVSSVAIMPNGDH--IVSASRDK 214
Query: 629 TVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
T+K+W + GH ++ V + DG+L AS D +W
Sbjct: 215 TIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVW 261
Score = 82.6 bits (195), Expect = 1e-15
Identities = 61/232 (26%), Positives = 108/232 (46%), Gaps = 21/232 (9%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDV 319
T+ GH+ V+ +A P D I+S+SRDKT+ +W++ + Y + K GH ++ V
Sbjct: 187 TMHGHDHNVSSVAIMPN-GDHIVSASRDKTIKMWEV---QTGYCV--KTFTGHREWVRMV 240
Query: 320 VLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQ---------- 469
+ DG S S D+T+R+W +A + +H V ++++ ++
Sbjct: 241 RPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSE 300
Query: 470 ----------IVSGSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSC 616
++SGSRDKTIK+W+ + C T+ GH +WV V F + I+SC
Sbjct: 301 TKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLV--GHDNWVRGVLF--HSGGKFILSC 356
Query: 617 GWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
D+T++VW N + H ++ ++ +G D +W+
Sbjct: 357 ADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
Score = 61.3 bits (142), Expect = 4e-09
Identities = 34/122 (27%), Positives = 59/122 (48%), Gaps = 1/122 (0%)
Frame = +2
Query: 422 HTKDVLSVAFSVDNRQIVSGSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHAN 598
H V V F +VS S D TIK+W+ + + T++ GH+D V + F +H+
Sbjct: 107 HRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLK--GHTDSVQDISF--DHSG 162
Query: 599 PIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLN 778
++ SC D T+K+W + GH +++V + P+G S +D +W++
Sbjct: 163 KLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQ 222
Query: 779 DG 784
G
Sbjct: 223 TG 224
>AF208837-1|AAL34972.1| 410|Homo sapiens Miller-Dieker
lissencephaly protein protein.
Length = 410
Score = 105 bits (253), Expect = 1e-22
Identities = 64/196 (32%), Positives = 97/196 (49%), Gaps = 1/196 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH VT++ +P + M+ S+S D T+ VW + G ++ L GH+ + D+
Sbjct: 104 LSGHRSPVTRVIFHPVFSVMV-SASEDATIKVW-----DYETGDFERTLKGHTDSVQDIS 157
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
G S S D T++LWD + R H +V SVA + IVS SRDKTIK
Sbjct: 158 FDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIK 217
Query: 503 LWNTLAECKYTIQD-DGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
+W + Y ++ GH +WV VR PN +I SC D+TV+VW + + K
Sbjct: 218 MWE--VQTGYCVKTFTGHREWVRMVR--PNQDGTLIASCSNDQTVRVWVVATKECKAELR 273
Query: 680 GHSGYLNTVTVSPDGS 727
H + ++ +P+ S
Sbjct: 274 EHEHVVECISWAPESS 289
Score = 84.2 bits (199), Expect = 5e-16
Identities = 53/167 (31%), Positives = 79/167 (47%), Gaps = 2/167 (1%)
Frame = +2
Query: 275 PQK-RLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAF 451
P+K L GH ++ V+ + +S S D T+++WD G R + HT V ++F
Sbjct: 99 PEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISF 158
Query: 452 SVDNRQIVSGSRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR 628
+ + S S D TIKLW+ EC T+ GH VS V PN + IVS D+
Sbjct: 159 DHSGKLLASCSADMTIKLWDFQGFECIRTMH--GHDHNVSSVAIMPNGDH--IVSASRDK 214
Query: 629 TVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
T+K+W + GH ++ V + DG+L AS D +W
Sbjct: 215 TIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVW 261
Score = 82.6 bits (195), Expect = 1e-15
Identities = 61/232 (26%), Positives = 108/232 (46%), Gaps = 21/232 (9%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDV 319
T+ GH+ V+ +A P D I+S+SRDKT+ +W++ + Y + K GH ++ V
Sbjct: 187 TMHGHDHNVSSVAIMPN-GDHIVSASRDKTIKMWEV---QTGYCV--KTFTGHREWVRMV 240
Query: 320 VLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQ---------- 469
+ DG S S D+T+R+W +A + +H V ++++ ++
Sbjct: 241 RPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSE 300
Query: 470 ----------IVSGSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSC 616
++SGSRDKTIK+W+ + C T+ GH +WV V F + I+SC
Sbjct: 301 TKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLV--GHDNWVRGVLF--HSGGKFILSC 356
Query: 617 GWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
D+T++VW N + H ++ ++ +G D +W+
Sbjct: 357 ADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
Score = 61.3 bits (142), Expect = 4e-09
Identities = 34/122 (27%), Positives = 59/122 (48%), Gaps = 1/122 (0%)
Frame = +2
Query: 422 HTKDVLSVAFSVDNRQIVSGSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHAN 598
H V V F +VS S D TIK+W+ + + T++ GH+D V + F +H+
Sbjct: 107 HRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLK--GHTDSVQDISF--DHSG 162
Query: 599 PIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLN 778
++ SC D T+K+W + GH +++V + P+G S +D +W++
Sbjct: 163 KLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQ 222
Query: 779 DG 784
G
Sbjct: 223 TG 224
>AL354928-6|CAI39637.1| 314|Homo sapiens WD repeat domain 38
protein.
Length = 314
Score = 105 bits (251), Expect = 2e-22
Identities = 66/219 (30%), Positives = 100/219 (45%), Gaps = 2/219 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH G V +P + S+S D T+ +W + R + + L GH + V
Sbjct: 59 LGGHTGPVKFCRFSPD-GHLFASASCDCTVRLWDVARAKC-----LRVLKGHQRSVETVS 112
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
S D SG WDK + LWD+ +G+ R H + S FS + +GS D T+
Sbjct: 113 FSPDSRQLASGGWDKRVMLWDVQSGQMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVH 172
Query: 503 LWNTLAECKYTIQD--DGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINH 676
+W+ +GHS +SC+ +S A+ ++ S WD+T+ +W T L I
Sbjct: 173 IWDLRMVTPAVSHQALEGHSANISCLCYS---ASGLLASGSWDKTIHIWKPTTSSLLIQL 229
Query: 677 LGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
GH ++ ++ SPD AS G +WD N GK L
Sbjct: 230 KGHVTWVKSIAFSPDELWLASAGYSRMVKVWDCNTGKCL 268
Score = 95.9 bits (228), Expect = 1e-19
Identities = 69/209 (33%), Positives = 98/209 (46%), Gaps = 3/209 (1%)
Frame = +2
Query: 152 HNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSS 331
H G V A +P M+L+ S D + W E G RL GH+ + S
Sbjct: 20 HGGEVNSSAFSPD-GQMLLTGSEDGCVYGW-----ETRSGQLLWRLGGHTGPVKFCRFSP 73
Query: 332 DGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN 511
DG+ S S D T+RLWD+A K R + H + V +V+FS D+RQ+ SG DK + LW+
Sbjct: 74 DGHLFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWD 133
Query: 512 TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL---G 682
+ + GH D + FSP N + + WD TV +W L ++H G
Sbjct: 134 VQSGQMLRLL-VGHRDSIQSSDFSPT-VN-CLATGSWDSTVHIWDLRMVTPAVSHQALEG 190
Query: 683 HSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
HS ++ + S G L ASG D +W
Sbjct: 191 HSANISCLCYSASG-LLASGSWDKTIHIW 218
Score = 87.0 bits (206), Expect = 7e-17
Identities = 60/206 (29%), Positives = 89/206 (43%), Gaps = 3/206 (1%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L+GH V ++ +P + S DK +++W + G + L GH I
Sbjct: 101 LKGHQRSVETVSFSPD-SRQLASGGWDKRVMLWDVQS-----GQMLRLLVGHRDSIQSSD 154
Query: 323 LSSDGNYALSGSWDKTLRLWDL---AAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDK 493
S N +GSWD T+ +WDL + + E H+ ++ + +S + SGS DK
Sbjct: 155 FSPTVNCLATGSWDSTVHIWDLRMVTPAVSHQALEGHSANISCLCYSASGL-LASGSWDK 213
Query: 494 TIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKIN 673
TI +W IQ GH WV + FSP+ + S G+ R VKVW K
Sbjct: 214 TIHIWKPTTS-SLLIQLKGHVTWVKSIAFSPDEL--WLASAGYSRMVKVWDCNTGKCLET 270
Query: 674 HLGHSGYLNTVTVSPDGSLCASGGKD 751
G +T +PDG + SG D
Sbjct: 271 LKGVLDVAHTCAFTPDGKILVSGAAD 296
Score = 72.9 bits (171), Expect = 1e-12
Identities = 45/134 (33%), Positives = 66/134 (49%)
Frame = +2
Query: 392 AGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSC 571
A + + F H +V S AFS D + +++GS D + W T + + + GH+ V
Sbjct: 10 AVRRVKFFGQHGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSG-QLLWRLGGHTGPVKF 68
Query: 572 VRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKD 751
RFSP+ + S D TV++W + K GH + TV+ SPD ASGG D
Sbjct: 69 CRFSPD--GHLFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWD 126
Query: 752 MXAMLWDLNDGKHL 793
MLWD+ G+ L
Sbjct: 127 KRVMLWDVQSGQML 140
Score = 47.2 bits (107), Expect = 7e-05
Identities = 29/118 (24%), Positives = 55/118 (46%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH+ ++ + + ++ S S DKT+ +WK T +L GH ++ +
Sbjct: 188 LEGHSANISCLCYSAS--GLLASGSWDKTIHIWKPTTSSLLI-----QLKGHVTWVKSIA 240
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKT 496
S D + S + + +++WD GK + + AF+ D + +VSG+ D+T
Sbjct: 241 FSPDELWLASAGYSRMVKVWDCNTGKCLETLKGVLDVAHTCAFTPDGKILVSGAADQT 298
>BC036377-1|AAH36377.1| 415|Homo sapiens WD repeat domain 69
protein.
Length = 415
Score = 103 bits (247), Expect = 7e-22
Identities = 64/226 (28%), Positives = 109/226 (48%), Gaps = 1/226 (0%)
Frame = +2
Query: 119 ETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGH 298
ET K T RGH + ++ NP+ ++ + S D T +W + E Y L GH
Sbjct: 165 ETGKCYHTFRGHTAEIVCLSFNPQ-STLVATGSMDTTAKLWDIQNGEEVY-----TLRGH 218
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVS 478
S I + ++ G+ ++GS+D T+ +WD G+ H ++ S +F+ D I++
Sbjct: 219 SAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILT 278
Query: 479 GSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 655
GS DKT KLW+ T +C T+ GH D + F ++ +I + D T +++
Sbjct: 279 GSMDKTCKLWDATNGKCVATL--TGHDDEILDSCF--DYTGKLIATASADGTARIFSAAT 334
Query: 656 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
K GH G ++ ++ +P G+ +G D A +WD G+ L
Sbjct: 335 RKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCL 380
Score = 96.3 bits (229), Expect = 1e-19
Identities = 66/227 (29%), Positives = 110/227 (48%), Gaps = 3/227 (1%)
Frame = +2
Query: 116 SETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
+ T L L+ H +T +A N K ++ S D+T +W E L G
Sbjct: 79 NHTFYLFKVLKAHILPLTNVALN-KSGSCFITGSYDRTCKLWDTASGEE-----LNTLEG 132
Query: 296 HSHFISDVVLSSD-GNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI 472
H + + + ++ G+ +GS+DKT +LW + GK F HT +++ ++F+ + +
Sbjct: 133 HRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLV 192
Query: 473 VSGSRDKTIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 649
+GS D T KLW+ E YT++ GHS + S N + I++ +D TV VW
Sbjct: 193 ATGSMDTTAKLWDIQNGEEVYTLR--GHS--AEIISLSFNTSGDRIITGSFDHTVVVWDA 248
Query: 650 TNCKLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGK 787
+ K+N L GH +++ + + D SL +G D LWD +GK
Sbjct: 249 DTGR-KVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGK 294
Score = 95.5 bits (227), Expect = 2e-19
Identities = 53/187 (28%), Positives = 100/187 (53%), Gaps = 2/187 (1%)
Frame = +2
Query: 242 KLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFED 421
KL ++ N+ K L H +++V L+ G+ ++GS+D+T +LWD A+G+ E
Sbjct: 73 KLGQNSNHTFYLFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEG 132
Query: 422 HTKDVLSVAFSVD-NRQIVSGSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHA 595
H V ++AF+ +I +GS DKT KLW+ +C +T + GH+ + C+ F+P
Sbjct: 133 HRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFR--GHTAEIVCLSFNPQ-- 188
Query: 596 NPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
+ ++ + D T K+W + N + GHS + +++ + G +G D ++WD
Sbjct: 189 STLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDA 248
Query: 776 NDGKHLH 796
+ G+ ++
Sbjct: 249 DTGRKVN 255
Score = 87.0 bits (206), Expect = 7e-17
Identities = 56/210 (26%), Positives = 97/210 (46%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDV 319
TLRGH+ + ++ N D I++ S D T++VW + + G L GH IS
Sbjct: 214 TLRGHSAEIISLSFNTS-GDRIITGSFDHTVVVW-----DADTGRKVNILIGHCAEISSA 267
Query: 320 VLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTI 499
+ D + L+GS DKT +LWD GK H ++L F + I + S D T
Sbjct: 268 SFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTA 327
Query: 500 KLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
++++ A K + +GH +S + F+P N ++ D+T ++W +
Sbjct: 328 RIFSA-ATRKCIAKLEGHEGEISKISFNPQ-GNHLLTGSS-DKTARIWDAQTGQCLQVLE 384
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
GH+ + + + G++ +G KD +W
Sbjct: 385 GHTDEIFSCAFNYKGNIVITGSKDNTCRIW 414
>AK098821-1|BAC05425.1| 415|Homo sapiens protein ( Homo sapiens
cDNA FLJ25955 fis, clone TST03904. ).
Length = 415
Score = 103 bits (247), Expect = 7e-22
Identities = 64/226 (28%), Positives = 109/226 (48%), Gaps = 1/226 (0%)
Frame = +2
Query: 119 ETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGH 298
ET K T RGH + ++ NP+ ++ + S D T +W + E Y L GH
Sbjct: 165 ETGKCYHTFRGHTAEIVCLSFNPQ-STLVATGSMDTTAKLWDIQNGEEVY-----TLRGH 218
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVS 478
S I + ++ G+ ++GS+D T+ +WD G+ H ++ S +F+ D I++
Sbjct: 219 SAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILT 278
Query: 479 GSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 655
GS DKT KLW+ T +C T+ GH D + F ++ +I + D T +++
Sbjct: 279 GSMDKTCKLWDATNGKCVATL--TGHDDEILDSCF--DYTGKLIATASADGTARIFSAAT 334
Query: 656 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
K GH G ++ ++ +P G+ +G D A +WD G+ L
Sbjct: 335 RKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCL 380
Score = 96.3 bits (229), Expect = 1e-19
Identities = 66/227 (29%), Positives = 112/227 (49%), Gaps = 3/227 (1%)
Frame = +2
Query: 116 SETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
+ T L L+ H +T +A N K ++ S D+T +W ++ G L G
Sbjct: 79 NHTFYLFKVLKAHILPLTNVALN-KSGSCFITGSYDRTCKLW-----DSASGEELNTLEG 132
Query: 296 HSHFISDVVLSSD-GNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI 472
H + + + ++ G+ +GS+DKT +LW + GK F HT +++ ++F+ + +
Sbjct: 133 HRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLV 192
Query: 473 VSGSRDKTIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 649
+GS D T KLW+ E YT++ GHS + S N + I++ +D TV VW
Sbjct: 193 ATGSMDTTAKLWDIQNGEEVYTLR--GHS--AEIISLSFNTSGDRIITGSFDHTVVVWDA 248
Query: 650 TNCKLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGK 787
+ K+N L GH +++ + + D SL +G D LWD +GK
Sbjct: 249 DTGR-KVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGK 294
Score = 95.1 bits (226), Expect = 3e-19
Identities = 53/187 (28%), Positives = 100/187 (53%), Gaps = 2/187 (1%)
Frame = +2
Query: 242 KLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFED 421
KL ++ N+ K L H +++V L+ G+ ++GS+D+T +LWD A+G+ E
Sbjct: 73 KLGQNSNHTFYLFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDSASGEELNTLEG 132
Query: 422 HTKDVLSVAFSVD-NRQIVSGSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHA 595
H V ++AF+ +I +GS DKT KLW+ +C +T + GH+ + C+ F+P
Sbjct: 133 HRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFR--GHTAEIVCLSFNPQ-- 188
Query: 596 NPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
+ ++ + D T K+W + N + GHS + +++ + G +G D ++WD
Sbjct: 189 STLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDA 248
Query: 776 NDGKHLH 796
+ G+ ++
Sbjct: 249 DTGRKVN 255
Score = 65.7 bits (153), Expect = 2e-10
Identities = 27/75 (36%), Positives = 44/75 (58%)
Frame = +2
Query: 284 RLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDN 463
+L GH IS + + GN+ L+GS DKT R+WD G+ + E HT ++ S AF+
Sbjct: 340 KLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKG 399
Query: 464 RQIVSGSRDKTIKLW 508
+++GS+ T ++W
Sbjct: 400 NIVITGSKGNTCRIW 414
>AK097409-1|BAC05039.1| 415|Homo sapiens protein ( Homo sapiens
cDNA FLJ40090 fis, clone TESTI2003596, weakly similar to
VEGETATIBLE INCOMPATIBILITY PROTEIN HET-E-1. ).
Length = 415
Score = 103 bits (247), Expect = 7e-22
Identities = 64/226 (28%), Positives = 109/226 (48%), Gaps = 1/226 (0%)
Frame = +2
Query: 119 ETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGH 298
ET K T RGH + ++ NP+ ++ + S D T +W + E Y L GH
Sbjct: 165 ETGKCYHTFRGHTAEIVCLSFNPQ-STLVATGSMDTTAKLWDIQNGEEVY-----TLRGH 218
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVS 478
S I + ++ G+ ++GS+D T+ +WD G+ H ++ S +F+ D I++
Sbjct: 219 SAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILT 278
Query: 479 GSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 655
GS DKT KLW+ T +C T+ GH D + F ++ +I + D T +++
Sbjct: 279 GSMDKTCKLWDATNGKCVATL--TGHDDEILDSCF--DYTGKLIATASADGTARIFSAAT 334
Query: 656 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
K GH G ++ ++ +P G+ +G D A +WD G+ L
Sbjct: 335 RKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCL 380
Score = 96.3 bits (229), Expect = 1e-19
Identities = 66/227 (29%), Positives = 110/227 (48%), Gaps = 3/227 (1%)
Frame = +2
Query: 116 SETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
+ T L L+ H +T +A N K ++ S D+T +W E L G
Sbjct: 79 NHTFYLFKVLKAHILPLTNVALN-KSGSCFITGSYDRTCKLWDTASGEE-----LNTLEG 132
Query: 296 HSHFISDVVLSSD-GNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI 472
H + + + ++ G+ +GS+DKT +LW + GK F HT +++ ++F+ + +
Sbjct: 133 HRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLV 192
Query: 473 VSGSRDKTIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 649
+GS D T KLW+ E YT++ GHS + S N + I++ +D TV VW
Sbjct: 193 ATGSMDTTAKLWDIQNGEEVYTLR--GHS--AEIISLSFNTSGDRIITGSFDHTVVVWDA 248
Query: 650 TNCKLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGK 787
+ K+N L GH +++ + + D SL +G D LWD +GK
Sbjct: 249 DTGR-KVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGK 294
Score = 95.5 bits (227), Expect = 2e-19
Identities = 53/187 (28%), Positives = 100/187 (53%), Gaps = 2/187 (1%)
Frame = +2
Query: 242 KLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFED 421
KL ++ N+ K L H +++V L+ G+ ++GS+D+T +LWD A+G+ E
Sbjct: 73 KLGQNSNHTFYLFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEG 132
Query: 422 HTKDVLSVAFSVD-NRQIVSGSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHA 595
H V ++AF+ +I +GS DKT KLW+ +C +T + GH+ + C+ F+P
Sbjct: 133 HRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFR--GHTAEIVCLSFNPQ-- 188
Query: 596 NPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
+ ++ + D T K+W + N + GHS + +++ + G +G D ++WD
Sbjct: 189 STLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDA 248
Query: 776 NDGKHLH 796
+ G+ ++
Sbjct: 249 DTGRKVN 255
Score = 87.0 bits (206), Expect = 7e-17
Identities = 56/210 (26%), Positives = 97/210 (46%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDV 319
TLRGH+ + ++ N D I++ S D T++VW + + G L GH IS
Sbjct: 214 TLRGHSAEIISLSFNTS-GDRIITGSFDHTVVVW-----DADTGRKVNILIGHCAEISSA 267
Query: 320 VLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTI 499
+ D + L+GS DKT +LWD GK H ++L F + I + S D T
Sbjct: 268 SFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTA 327
Query: 500 KLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
++++ A K + +GH +S + F+P N ++ D+T ++W +
Sbjct: 328 RIFSA-ATRKCIAKLEGHEGEISKISFNPQ-GNHLLTGSS-DKTARIWDAQTGQCLQVLE 384
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
GH+ + + + G++ +G KD +W
Sbjct: 385 GHTDEIFSCAFNYKGNIVITGSKDNTCRIW 414
>AC073065-2|AAX93215.1| 415|Homo sapiens unknown protein.
Length = 415
Score = 103 bits (247), Expect = 7e-22
Identities = 64/226 (28%), Positives = 109/226 (48%), Gaps = 1/226 (0%)
Frame = +2
Query: 119 ETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGH 298
ET K T RGH + ++ NP+ ++ + S D T +W + E Y L GH
Sbjct: 165 ETGKCYHTFRGHTAEIVCLSFNPQ-STLVATGSMDTTAKLWDIQNGEEVY-----TLRGH 218
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVS 478
S I + ++ G+ ++GS+D T+ +WD G+ H ++ S +F+ D I++
Sbjct: 219 SAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILT 278
Query: 479 GSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 655
GS DKT KLW+ T +C T+ GH D + F ++ +I + D T +++
Sbjct: 279 GSMDKTCKLWDATNGKCVATL--TGHDDEILDSCF--DYTGKLIATASADGTARIFSAAT 334
Query: 656 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
K GH G ++ ++ +P G+ +G D A +WD G+ L
Sbjct: 335 RKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCL 380
Score = 96.3 bits (229), Expect = 1e-19
Identities = 66/227 (29%), Positives = 110/227 (48%), Gaps = 3/227 (1%)
Frame = +2
Query: 116 SETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
+ T L L+ H +T +A N K ++ S D+T +W E L G
Sbjct: 79 NHTFYLFKVLKAHILPLTNVALN-KSGSCFITGSYDRTCKLWDTASGEE-----LNTLEG 132
Query: 296 HSHFISDVVLSSD-GNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI 472
H + + + ++ G+ +GS+DKT +LW + GK F HT +++ ++F+ + +
Sbjct: 133 HRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLV 192
Query: 473 VSGSRDKTIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 649
+GS D T KLW+ E YT++ GHS + S N + I++ +D TV VW
Sbjct: 193 ATGSMDTTAKLWDIQNGEEVYTLR--GHS--AEIISLSFNTSGDRIITGSFDHTVVVWDA 248
Query: 650 TNCKLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGK 787
+ K+N L GH +++ + + D SL +G D LWD +GK
Sbjct: 249 DTGR-KVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGK 294
Score = 95.5 bits (227), Expect = 2e-19
Identities = 53/187 (28%), Positives = 100/187 (53%), Gaps = 2/187 (1%)
Frame = +2
Query: 242 KLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFED 421
KL ++ N+ K L H +++V L+ G+ ++GS+D+T +LWD A+G+ E
Sbjct: 73 KLGQNSNHTFYLFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEG 132
Query: 422 HTKDVLSVAFSVD-NRQIVSGSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHA 595
H V ++AF+ +I +GS DKT KLW+ +C +T + GH+ + C+ F+P
Sbjct: 133 HRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFR--GHTAEIVCLSFNPQ-- 188
Query: 596 NPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
+ ++ + D T K+W + N + GHS + +++ + G +G D ++WD
Sbjct: 189 STLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDA 248
Query: 776 NDGKHLH 796
+ G+ ++
Sbjct: 249 DTGRKVN 255
Score = 87.0 bits (206), Expect = 7e-17
Identities = 56/210 (26%), Positives = 97/210 (46%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDV 319
TLRGH+ + ++ N D I++ S D T++VW + + G L GH IS
Sbjct: 214 TLRGHSAEIISLSFNTS-GDRIITGSFDHTVVVW-----DADTGRKVNILIGHCAEISSA 267
Query: 320 VLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTI 499
+ D + L+GS DKT +LWD GK H ++L F + I + S D T
Sbjct: 268 SFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTA 327
Query: 500 KLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
++++ A K + +GH +S + F+P N ++ D+T ++W +
Sbjct: 328 RIFSA-ATRKCIAKLEGHEGEISKISFNPQ-GNHLLTGSS-DKTARIWDAQTGQCLQVLE 384
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
GH+ + + + G++ +G KD +W
Sbjct: 385 GHTDEIFSCAFNYKGNIVITGSKDNTCRIW 414
>CR456762-1|CAG33043.1| 655|Homo sapiens KATNB1 protein.
Length = 655
Score = 101 bits (243), Expect = 2e-21
Identities = 58/164 (35%), Positives = 84/164 (51%), Gaps = 1/164 (0%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNR 466
L GH+ + V L++ ++GS ++R+WDL A K R H ++ S+ F
Sbjct: 59 LTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGE 118
Query: 467 QIVSGSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVW 643
+ SGS+D IKLW+ + C + + GHS V C+RFSP+ + S D TVK+W
Sbjct: 119 FVASGSQDTNIKLWDIRRKGCVFRYR--GHSQAVRCLRFSPD--GKWLASAADDHTVKLW 174
Query: 644 HLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
LT K+ GH+G +N V P+ L ASG D WDL
Sbjct: 175 DLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDL 218
Score = 87.0 bits (206), Expect = 7e-17
Identities = 58/204 (28%), Positives = 96/204 (47%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDV 319
+L GH V + N ++I++ S+ ++ VW L + + L GH I +
Sbjct: 58 SLTGHTSPVESVRLNTP-EELIVAGSQSGSIRVWDLEAAKI-----LRTLMGHKANICSL 111
Query: 320 VLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTI 499
G + SGS D ++LWD+ R+ H++ V + FS D + + S + D T+
Sbjct: 112 DFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTV 171
Query: 500 KLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
KLW+ A K + GH+ V+ V F PN ++ S DRT++ W L ++
Sbjct: 172 KLWDLTAG-KMMSEFPGHTGPVNVVEFHPNEY--LLASGSSDRTIRFWDLEKFQVVSCIE 228
Query: 680 GHSGYLNTVTVSPDGSLCASGGKD 751
G G + +V +PDG SG +D
Sbjct: 229 GEPGPVRSVLFNPDGCCLYSGCQD 252
Score = 77.8 bits (183), Expect = 4e-14
Identities = 49/157 (31%), Positives = 76/157 (48%)
Frame = +2
Query: 119 ETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGH 298
E K+ TL GH + + +P Y + + S S+D + +W + R + R GH
Sbjct: 93 EAAKILRTLMGHKANICSLDFHP-YGEFVASGSQDTNIKLWDIRRKGCVF-----RYRGH 146
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVS 478
S + + S DG + S + D T++LWDL AGK F HT V V F + + S
Sbjct: 147 SQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLAS 206
Query: 479 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPN 589
GS D+TI+ W+ L + + +G V V F+P+
Sbjct: 207 GSSDRTIRFWD-LEKFQVVSCIEGEPGPVRSVLFNPD 242
Score = 71.3 bits (167), Expect = 4e-12
Identities = 46/170 (27%), Positives = 71/170 (41%), Gaps = 1/170 (0%)
Frame = +2
Query: 281 KRLYGHSHFISDVVLS-SDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSV 457
+ + H+ +S +VL + G +G D + LW + HT V SV +
Sbjct: 14 QEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNT 73
Query: 458 DNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVK 637
IV+GS+ +I++W+ L K GH + + F P + S D +K
Sbjct: 74 PEELIVAGSQSGSIRVWD-LEAAKILRTLMGHKANICSLDFHPY--GEFVASGSQDTNIK 130
Query: 638 VWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGK 787
+W + + GHS + + SPDG AS D LWDL GK
Sbjct: 131 LWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGK 180
>BT007022-1|AAP35668.1| 655|Homo sapiens katanin p80
(WD40-containing) subunit B 1 protein.
Length = 655
Score = 101 bits (243), Expect = 2e-21
Identities = 58/164 (35%), Positives = 84/164 (51%), Gaps = 1/164 (0%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNR 466
L GH+ + V L++ ++GS ++R+WDL A K R H ++ S+ F
Sbjct: 59 LTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGE 118
Query: 467 QIVSGSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVW 643
+ SGS+D IKLW+ + C + + GHS V C+RFSP+ + S D TVK+W
Sbjct: 119 FVASGSQDTNIKLWDIRRKGCVFRYR--GHSQAVRCLRFSPD--GKWLASAADDHTVKLW 174
Query: 644 HLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
LT K+ GH+G +N V P+ L ASG D WDL
Sbjct: 175 DLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDL 218
Score = 87.0 bits (206), Expect = 7e-17
Identities = 58/204 (28%), Positives = 96/204 (47%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDV 319
+L GH V + N ++I++ S+ ++ VW L + + L GH I +
Sbjct: 58 SLTGHTSPVESVRLNTP-EELIVAGSQSGSIRVWDLEAAKI-----LRTLMGHKANICSL 111
Query: 320 VLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTI 499
G + SGS D ++LWD+ R+ H++ V + FS D + + S + D T+
Sbjct: 112 DFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTV 171
Query: 500 KLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
KLW+ A K + GH+ V+ V F PN ++ S DRT++ W L ++
Sbjct: 172 KLWDLTAG-KMMSEFPGHTGPVNVVEFHPNEY--LLASGSSDRTIRFWDLEKFQVVSCIE 228
Query: 680 GHSGYLNTVTVSPDGSLCASGGKD 751
G G + +V +PDG SG +D
Sbjct: 229 GEPGPVRSVLFNPDGCCLYSGCQD 252
Score = 77.8 bits (183), Expect = 4e-14
Identities = 49/157 (31%), Positives = 76/157 (48%)
Frame = +2
Query: 119 ETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGH 298
E K+ TL GH + + +P Y + + S S+D + +W + R + R GH
Sbjct: 93 EAAKILRTLMGHKANICSLDFHP-YGEFVASGSQDTNIKLWDIRRKGCVF-----RYRGH 146
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVS 478
S + + S DG + S + D T++LWDL AGK F HT V V F + + S
Sbjct: 147 SQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLAS 206
Query: 479 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPN 589
GS D+TI+ W+ L + + +G V V F+P+
Sbjct: 207 GSSDRTIRFWD-LEKFQVVSCIEGEPGPVRSVLFNPD 242
Score = 71.3 bits (167), Expect = 4e-12
Identities = 46/170 (27%), Positives = 71/170 (41%), Gaps = 1/170 (0%)
Frame = +2
Query: 281 KRLYGHSHFISDVVLS-SDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSV 457
+ + H+ +S +VL + G +G D + LW + HT V SV +
Sbjct: 14 QEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNT 73
Query: 458 DNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVK 637
IV+GS+ +I++W+ L K GH + + F P + S D +K
Sbjct: 74 PEELIVAGSQSGSIRVWD-LEAAKILRTLMGHKANICSLDFHPY--GEFVASGSQDTNIK 130
Query: 638 VWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGK 787
+W + + GHS + + SPDG AS D LWDL GK
Sbjct: 131 LWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGK 180
>BC001353-1|AAH01353.1| 655|Homo sapiens katanin p80 (WD repeat
containing) subunit B 1 protein.
Length = 655
Score = 101 bits (243), Expect = 2e-21
Identities = 58/164 (35%), Positives = 84/164 (51%), Gaps = 1/164 (0%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNR 466
L GH+ + V L++ ++GS ++R+WDL A K R H ++ S+ F
Sbjct: 59 LTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGE 118
Query: 467 QIVSGSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVW 643
+ SGS+D IKLW+ + C + + GHS V C+RFSP+ + S D TVK+W
Sbjct: 119 FVASGSQDTNIKLWDIRRKGCVFRYR--GHSQAVRCLRFSPD--GKWLASAADDHTVKLW 174
Query: 644 HLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
LT K+ GH+G +N V P+ L ASG D WDL
Sbjct: 175 DLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDL 218
Score = 87.0 bits (206), Expect = 7e-17
Identities = 58/204 (28%), Positives = 96/204 (47%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDV 319
+L GH V + N ++I++ S+ ++ VW L + + L GH I +
Sbjct: 58 SLTGHTSPVESVRLNTP-EELIVAGSQSGSIRVWDLEAAKI-----LRTLMGHKANICSL 111
Query: 320 VLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTI 499
G + SGS D ++LWD+ R+ H++ V + FS D + + S + D T+
Sbjct: 112 DFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTV 171
Query: 500 KLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
KLW+ A K + GH+ V+ V F PN ++ S DRT++ W L ++
Sbjct: 172 KLWDLTAG-KMMSEFPGHTGPVNVVEFHPNEY--LLASGSSDRTIRFWDLEKFQVVSCIE 228
Query: 680 GHSGYLNTVTVSPDGSLCASGGKD 751
G G + +V +PDG SG +D
Sbjct: 229 GEPGPVRSVLFNPDGCCLYSGCQD 252
Score = 77.8 bits (183), Expect = 4e-14
Identities = 49/157 (31%), Positives = 76/157 (48%)
Frame = +2
Query: 119 ETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGH 298
E K+ TL GH + + +P Y + + S S+D + +W + R + R GH
Sbjct: 93 EAAKILRTLMGHKANICSLDFHP-YGEFVASGSQDTNIKLWDIRRKGCVF-----RYRGH 146
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVS 478
S + + S DG + S + D T++LWDL AGK F HT V V F + + S
Sbjct: 147 SQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLAS 206
Query: 479 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPN 589
GS D+TI+ W+ L + + +G V V F+P+
Sbjct: 207 GSSDRTIRFWD-LEKFQVVSCIEGEPGPVRSVLFNPD 242
Score = 71.3 bits (167), Expect = 4e-12
Identities = 46/170 (27%), Positives = 71/170 (41%), Gaps = 1/170 (0%)
Frame = +2
Query: 281 KRLYGHSHFISDVVLS-SDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSV 457
+ + H+ +S +VL + G +G D + LW + HT V SV +
Sbjct: 14 QEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNT 73
Query: 458 DNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVK 637
IV+GS+ +I++W+ L K GH + + F P + S D +K
Sbjct: 74 PEELIVAGSQSGSIRVWD-LEAAKILRTLMGHKANICSLDFHPY--GEFVASGSQDTNIK 130
Query: 638 VWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGK 787
+W + + GHS + + SPDG AS D LWDL GK
Sbjct: 131 LWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGK 180
>AF208838-1|AAL34973.1| 410|Homo sapiens Miller-Dieker
lissencephaly protein protein.
Length = 410
Score = 100 bits (239), Expect = 7e-21
Identities = 63/196 (32%), Positives = 96/196 (48%), Gaps = 1/196 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH VT++ +P + M+ S+S D T+ VW + G ++ L GH+ + D+
Sbjct: 104 LSGHRSPVTRVIFHPVFSVMV-SASEDATIKVW-----DYETGDFERTLKGHTDSVQDIS 157
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
G S S D T++L D + R H +V SVA + IVS SRDKTIK
Sbjct: 158 FDHSGKLLASCSADMTIKLRDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIK 217
Query: 503 LWNTLAECKYTIQD-DGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
+W + Y ++ GH +WV VR PN +I SC D+TV+VW + + K
Sbjct: 218 MWEV--QTGYCVKTFTGHREWVRMVR--PNQDGTLIASCSNDQTVRVWVVATKECKAELR 273
Query: 680 GHSGYLNTVTVSPDGS 727
H + ++ +P+ S
Sbjct: 274 EHEHVVECISWAPESS 289
Score = 84.2 bits (199), Expect = 5e-16
Identities = 61/237 (25%), Positives = 108/237 (45%), Gaps = 19/237 (8%)
Frame = +2
Query: 119 ETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGH 298
ET TL+GH V I+ + ++ S S D T+ KL RD + + ++GH
Sbjct: 138 ETGDFERTLKGHTDSVQDISFDHS-GKLLASCSADMTI---KL-RDFQGFECI-RTMHGH 191
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVS 478
H +S V + +G++ +S S DKT+++W++ G + F H + V V + D I S
Sbjct: 192 DHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIAS 251
Query: 479 GSRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHA------------------NP 601
S D+T+++W ECK +++ H V C+ ++P + P
Sbjct: 252 CSNDQTVRVWVVATKECKAELRE--HEHVVECISWAPESSYSSISEATGSETKKSGKPGP 309
Query: 602 IIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
++S D+T+K+W ++ + +GH ++ V G S D +WD
Sbjct: 310 FLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWD 366
Score = 82.6 bits (195), Expect = 1e-15
Identities = 61/232 (26%), Positives = 108/232 (46%), Gaps = 21/232 (9%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDV 319
T+ GH+ V+ +A P D I+S+SRDKT+ +W++ + Y + K GH ++ V
Sbjct: 187 TMHGHDHNVSSVAIMPN-GDHIVSASRDKTIKMWEV---QTGYCV--KTFTGHREWVRMV 240
Query: 320 VLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQ---------- 469
+ DG S S D+T+R+W +A + +H V ++++ ++
Sbjct: 241 RPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSE 300
Query: 470 ----------IVSGSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSC 616
++SGSRDKTIK+W+ + C T+ GH +WV V F + I+SC
Sbjct: 301 TKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLV--GHDNWVRGVLF--HSGGKFILSC 356
Query: 617 GWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
D+T++VW N + H ++ ++ +G D +W+
Sbjct: 357 ADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
Score = 78.6 bits (185), Expect = 2e-14
Identities = 52/167 (31%), Positives = 78/167 (46%), Gaps = 2/167 (1%)
Frame = +2
Query: 275 PQK-RLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAF 451
P+K L GH ++ V+ + +S S D T+++WD G R + HT V ++F
Sbjct: 99 PEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISF 158
Query: 452 SVDNRQIVSGSRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR 628
+ + S S D TIKL + EC T+ GH VS V PN + IVS D+
Sbjct: 159 DHSGKLLASCSADMTIKLRDFQGFECIRTMH--GHDHNVSSVAIMPNGDH--IVSASRDK 214
Query: 629 TVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
T+K+W + GH ++ V + DG+L AS D +W
Sbjct: 215 TIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVW 261
Score = 55.6 bits (128), Expect = 2e-07
Identities = 33/122 (27%), Positives = 58/122 (47%), Gaps = 1/122 (0%)
Frame = +2
Query: 422 HTKDVLSVAFSVDNRQIVSGSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHAN 598
H V V F +VS S D TIK+W+ + + T++ GH+D V + F +H+
Sbjct: 107 HRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLK--GHTDSVQDISF--DHSG 162
Query: 599 PIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLN 778
++ SC D T+K+ + GH +++V + P+G S +D +W++
Sbjct: 163 KLLASCSADMTIKLRDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQ 222
Query: 779 DG 784
G
Sbjct: 223 TG 224
Score = 35.9 bits (79), Expect = 0.17
Identities = 25/82 (30%), Positives = 36/82 (43%)
Frame = +2
Query: 527 KYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTV 706
KY + GH V+ V F P + ++VS D T+KVW + GH+ + +
Sbjct: 101 KYALS--GHRSPVTRVIFHPVFS--VMVSASEDATIKVWDYETGDFERTLKGHTDSVQDI 156
Query: 707 TVSPDGSLCASGGKDMXAMLWD 772
+ G L AS DM L D
Sbjct: 157 SFDHSGKLLASCSADMTIKLRD 178
>BC012075-1|AAH12075.1| 485|Homo sapiens notchless homolog 1
(Drosophila) protein.
Length = 485
Score = 98.7 bits (235), Expect = 2e-20
Identities = 52/150 (34%), Positives = 81/150 (54%)
Frame = +2
Query: 194 PDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTL 373
P+ ++S S D TL +W D+ P R+ GH I+ V+ S D S S+DK++
Sbjct: 341 PERLVSGSDDFTLFLWSPAEDKK----PLTRMTGHQALINQVLFSPDSRIVASASFDKSI 396
Query: 374 RLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGH 553
+LWD GK H V +A+S D+R +VSGS D T+K+W+ A+ K + GH
Sbjct: 397 KLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQ-KLAMDLPGH 455
Query: 554 SDWVSCVRFSPNHANPIIVSCGWDRTVKVW 643
+D V V +SP+ + S G D+ +++W
Sbjct: 456 ADEVYAVDWSPDGQR--VASGGKDKCLRIW 483
Score = 89.4 bits (212), Expect = 1e-17
Identities = 52/169 (30%), Positives = 82/169 (48%), Gaps = 3/169 (1%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNR 466
L GHS + V S G Y SGS D T+R WDL+ + H VLS+++S D +
Sbjct: 110 LEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGK 169
Query: 467 QIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANP---IIVSCGWDRTVK 637
++ SG ++ I LW+ + GHS W++ + + P HANP + S D +V+
Sbjct: 170 KLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVR 229
Query: 638 VWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDG 784
+W T + + GH+ + + DG L S +D +W +DG
Sbjct: 230 IWDTTAGRCERILTGHTQSVTCLRWGGDG-LLYSASQDRTIKVWRAHDG 277
Score = 79.0 bits (186), Expect = 2e-14
Identities = 54/142 (38%), Positives = 73/142 (51%), Gaps = 1/142 (0%)
Frame = +2
Query: 347 LSGSWDKTLRLWDLAAGKTT-RRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAE 523
+SGS D TL LW A K R H + V FS D+R + S S DK+IKLW+
Sbjct: 345 VSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTG 404
Query: 524 CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNT 703
KY GH V + +S + + ++VS D T+KVW + KL ++ GH+ +
Sbjct: 405 -KYLASLRGHVAAVYQIAWSAD--SRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYA 461
Query: 704 VTVSPDGSLCASGGKDMXAMLW 769
V SPDG ASGGKD +W
Sbjct: 462 VDWSPDGQRVASGGKDKCLRIW 483
Score = 73.7 bits (173), Expect = 7e-13
Identities = 52/200 (26%), Positives = 100/200 (50%), Gaps = 4/200 (2%)
Frame = +2
Query: 200 MILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYAL-SGSWDK--- 367
++ S+S+D+T+ VW+ + G+ + L GH H+++ + LS+D YAL +G+++
Sbjct: 259 LLYSASQDRTIKVWRA-----HDGVLCRTLQGHGHWVNTMALSTD--YALRTGAFEPAEA 311
Query: 368 TLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDD 547
++ DL + + ++ ++ ++VSGS D T+ LW+ + K +
Sbjct: 312 SVNPQDLQG--SLQELKERALSRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMT 369
Query: 548 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 727
GH ++ V FSP+ + I+ S +D+++K+W K + GH + + S D
Sbjct: 370 GHQALINQVLFSPD--SRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSR 427
Query: 728 LCASGGKDMXAMLWDLNDGK 787
L SG D +WD+ K
Sbjct: 428 LLVSGSSDSTLKVWDVKAQK 447
Score = 65.3 bits (152), Expect = 2e-10
Identities = 57/223 (25%), Positives = 99/223 (44%), Gaps = 5/223 (2%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPD----MILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHF 307
TL GH+ W+T ++ P + + + SSS+D ++ +W T G ++ L GH+
Sbjct: 194 TLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTTA-----GRCERILTGHTQS 248
Query: 308 ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSR 487
++ + DG S S D+T+++W G R + H V ++A S D + +G+
Sbjct: 249 VTCLRWGGDG-LLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALSTDYA-LRTGAF 306
Query: 488 DKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLK 667
+ N + + ++Q+ +S +VS D T+ +W K
Sbjct: 307 EPAEASVNP-QDLQGSLQELKERA-LSRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKP 364
Query: 668 INHL-GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ + GH +N V SPD + AS D LWD GK+L
Sbjct: 365 LTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYL 407
Score = 62.9 bits (146), Expect = 1e-09
Identities = 45/159 (28%), Positives = 78/159 (49%), Gaps = 7/159 (4%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDV 319
T +GH WV I+ +P + S ++ +++W D + + L GHS +I+ +
Sbjct: 151 TCKGHRHWVLSISWSPD-GKKLASGCKNGQILLW----DPSTGKQVGRTLAGHSKWITGL 205
Query: 320 V-----LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGS 484
+ + Y S S D ++R+WD AG+ R HT+ V + + D + S S
Sbjct: 206 SWEPLHANPECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDG-LLYSAS 264
Query: 485 RDKTIKLWNTL--AECKYTIQDDGHSDWVSCVRFSPNHA 595
+D+TIK+W C+ T+Q GH WV+ + S ++A
Sbjct: 265 QDRTIKVWRAHDGVLCR-TLQ--GHGHWVNTMALSTDYA 300
Score = 56.4 bits (130), Expect = 1e-07
Identities = 38/139 (27%), Positives = 64/139 (46%), Gaps = 6/139 (4%)
Frame = +2
Query: 389 AAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVS 568
A + T E H++ V+SVAFS + + SGS D T++ W+ E + GH WV
Sbjct: 102 AVTRCTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPH-FTCKGHRHWVL 160
Query: 569 CVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL-GHSGYLNTVT-----VSPDGSL 730
+ +SP+ + C + + +W + K L GHS ++ ++ +P+
Sbjct: 161 SISWSPD-GKKLASGCK-NGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRY 218
Query: 731 CASGGKDMXAMLWDLNDGK 787
AS KD +WD G+
Sbjct: 219 VASSSKDGSVRIWDTTAGR 237
Score = 52.4 bits (120), Expect = 2e-06
Identities = 31/97 (31%), Positives = 48/97 (49%)
Frame = +2
Query: 503 LWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLG 682
++ A + T +GHS+ V V FSP + S D TV+ W L+ G
Sbjct: 97 IFRVRAVTRCTSSLEGHSEAVISVAFSPT--GKYLASGSGDTTVRFWDLSTETPHFTCKG 154
Query: 683 HSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
H ++ +++ SPDG ASG K+ +LWD + GK +
Sbjct: 155 HRHWVLSISWSPDGKKLASGCKNGQILLWDPSTGKQV 191
>BC002884-1|AAH02884.2| 484|Homo sapiens NLE1 protein protein.
Length = 484
Score = 98.7 bits (235), Expect = 2e-20
Identities = 52/150 (34%), Positives = 81/150 (54%)
Frame = +2
Query: 194 PDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTL 373
P+ ++S S D TL +W D+ P R+ GH I+ V+ S D S S+DK++
Sbjct: 340 PERLVSGSDDFTLFLWSPAEDKK----PLTRMTGHQALINQVLFSPDSRIVASASFDKSI 395
Query: 374 RLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGH 553
+LWD GK H V +A+S D+R +VSGS D T+K+W+ A+ K + GH
Sbjct: 396 KLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQ-KLAMDLPGH 454
Query: 554 SDWVSCVRFSPNHANPIIVSCGWDRTVKVW 643
+D V V +SP+ + S G D+ +++W
Sbjct: 455 ADEVYAVDWSPDGQR--VASGGKDKCLRIW 482
Score = 89.4 bits (212), Expect = 1e-17
Identities = 52/169 (30%), Positives = 82/169 (48%), Gaps = 3/169 (1%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNR 466
L GHS + V S G Y SGS D T+R WDL+ + H VLS+++S D +
Sbjct: 109 LEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGK 168
Query: 467 QIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANP---IIVSCGWDRTVK 637
++ SG ++ I LW+ + GHS W++ + + P HANP + S D +V+
Sbjct: 169 KLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVR 228
Query: 638 VWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDG 784
+W T + + GH+ + + DG L S +D +W +DG
Sbjct: 229 IWDTTAGRCERILTGHTQSVTCLRWGGDG-LLYSASQDRTIKVWRAHDG 276
Score = 79.0 bits (186), Expect = 2e-14
Identities = 54/142 (38%), Positives = 73/142 (51%), Gaps = 1/142 (0%)
Frame = +2
Query: 347 LSGSWDKTLRLWDLAAGKTT-RRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAE 523
+SGS D TL LW A K R H + V FS D+R + S S DK+IKLW+
Sbjct: 344 VSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTG 403
Query: 524 CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNT 703
KY GH V + +S + + ++VS D T+KVW + KL ++ GH+ +
Sbjct: 404 -KYLASLRGHVAAVYQIAWSAD--SRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYA 460
Query: 704 VTVSPDGSLCASGGKDMXAMLW 769
V SPDG ASGGKD +W
Sbjct: 461 VDWSPDGQRVASGGKDKCLRIW 482
Score = 73.7 bits (173), Expect = 7e-13
Identities = 52/200 (26%), Positives = 100/200 (50%), Gaps = 4/200 (2%)
Frame = +2
Query: 200 MILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYAL-SGSWDK--- 367
++ S+S+D+T+ VW+ + G+ + L GH H+++ + LS+D YAL +G+++
Sbjct: 258 LLYSASQDRTIKVWRA-----HDGVLCRTLQGHGHWVNTMALSTD--YALRTGAFEPAEA 310
Query: 368 TLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDD 547
++ DL + + ++ ++ ++VSGS D T+ LW+ + K +
Sbjct: 311 SVNPQDLQG--SLQELKERALSRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMT 368
Query: 548 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 727
GH ++ V FSP+ + I+ S +D+++K+W K + GH + + S D
Sbjct: 369 GHQALINQVLFSPD--SRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSR 426
Query: 728 LCASGGKDMXAMLWDLNDGK 787
L SG D +WD+ K
Sbjct: 427 LLVSGSSDSTLKVWDVKAQK 446
Score = 65.3 bits (152), Expect = 2e-10
Identities = 57/223 (25%), Positives = 99/223 (44%), Gaps = 5/223 (2%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPD----MILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHF 307
TL GH+ W+T ++ P + + + SSS+D ++ +W T G ++ L GH+
Sbjct: 193 TLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTTA-----GRCERILTGHTQS 247
Query: 308 ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSR 487
++ + DG S S D+T+++W G R + H V ++A S D + +G+
Sbjct: 248 VTCLRWGGDG-LLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALSTDYA-LRTGAF 305
Query: 488 DKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLK 667
+ N + + ++Q+ +S +VS D T+ +W K
Sbjct: 306 EPAEASVNP-QDLQGSLQELKERA-LSRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKP 363
Query: 668 INHL-GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ + GH +N V SPD + AS D LWD GK+L
Sbjct: 364 LTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYL 406
Score = 62.9 bits (146), Expect = 1e-09
Identities = 45/159 (28%), Positives = 78/159 (49%), Gaps = 7/159 (4%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDV 319
T +GH WV I+ +P + S ++ +++W D + + L GHS +I+ +
Sbjct: 150 TCKGHRHWVLSISWSPD-GKKLASGCKNGQILLW----DPSTGKQVGRTLAGHSKWITGL 204
Query: 320 V-----LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGS 484
+ + Y S S D ++R+WD AG+ R HT+ V + + D + S S
Sbjct: 205 SWEPLHANPECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDG-LLYSAS 263
Query: 485 RDKTIKLWNTL--AECKYTIQDDGHSDWVSCVRFSPNHA 595
+D+TIK+W C+ T+Q GH WV+ + S ++A
Sbjct: 264 QDRTIKVWRAHDGVLCR-TLQ--GHGHWVNTMALSTDYA 299
Score = 56.4 bits (130), Expect = 1e-07
Identities = 38/139 (27%), Positives = 64/139 (46%), Gaps = 6/139 (4%)
Frame = +2
Query: 389 AAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVS 568
A + T E H++ V+SVAFS + + SGS D T++ W+ E + GH WV
Sbjct: 101 AVTRCTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPH-FTCKGHRHWVL 159
Query: 569 CVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL-GHSGYLNTVT-----VSPDGSL 730
+ +SP+ + C + + +W + K L GHS ++ ++ +P+
Sbjct: 160 SISWSPD-GKKLASGCK-NGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRY 217
Query: 731 CASGGKDMXAMLWDLNDGK 787
AS KD +WD G+
Sbjct: 218 VASSSKDGSVRIWDTTAGR 236
Score = 52.4 bits (120), Expect = 2e-06
Identities = 31/97 (31%), Positives = 48/97 (49%)
Frame = +2
Query: 503 LWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLG 682
++ A + T +GHS+ V V FSP + S D TV+ W L+ G
Sbjct: 96 IFRVRAVTRCTSSLEGHSEAVISVAFSPT--GKYLASGSGDTTVRFWDLSTETPHFTCKG 153
Query: 683 HSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
H ++ +++ SPDG ASG K+ +LWD + GK +
Sbjct: 154 HRHWVLSISWSPDGKKLASGCKNGQILLWDPSTGKQV 190
>AK001320-1|BAA91621.1| 485|Homo sapiens protein ( Homo sapiens
cDNA FLJ10458 fis, clone NT2RP1001457, highly similar to
Homo sapiens partial mRNA for beta-transducin family
protein. ).
Length = 485
Score = 98.7 bits (235), Expect = 2e-20
Identities = 52/150 (34%), Positives = 81/150 (54%)
Frame = +2
Query: 194 PDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTL 373
P+ ++S S D TL +W D+ P R+ GH I+ V+ S D S S+DK++
Sbjct: 341 PERLVSGSDDFTLFLWSPAEDKK----PLTRMTGHQALINQVLFSPDSRIVASASFDKSI 396
Query: 374 RLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGH 553
+LWD GK H V +A+S D+R +VSGS D T+K+W+ A+ K + GH
Sbjct: 397 KLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQ-KLAMDLPGH 455
Query: 554 SDWVSCVRFSPNHANPIIVSCGWDRTVKVW 643
+D V V +SP+ + S G D+ +++W
Sbjct: 456 ADEVYAVDWSPDGQR--VASGGKDKCLRIW 483
Score = 89.4 bits (212), Expect = 1e-17
Identities = 52/169 (30%), Positives = 82/169 (48%), Gaps = 3/169 (1%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNR 466
L GHS + V S G Y SGS D T+R WDL+ + H VLS+++S D +
Sbjct: 110 LEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGK 169
Query: 467 QIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANP---IIVSCGWDRTVK 637
++ SG ++ I LW+ + GHS W++ + + P HANP + S D +V+
Sbjct: 170 KLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVR 229
Query: 638 VWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDG 784
+W T + + GH+ + + DG L S +D +W +DG
Sbjct: 230 IWDTTAGRCERILTGHTQSVTCLRWGGDG-LLYSASQDRTIKVWRAHDG 277
Score = 79.0 bits (186), Expect = 2e-14
Identities = 54/142 (38%), Positives = 73/142 (51%), Gaps = 1/142 (0%)
Frame = +2
Query: 347 LSGSWDKTLRLWDLAAGKTT-RRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAE 523
+SGS D TL LW A K R H + V FS D+R + S S DK+IKLW+
Sbjct: 345 VSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTG 404
Query: 524 CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNT 703
KY GH V + +S + + ++VS D T+KVW + KL ++ GH+ +
Sbjct: 405 -KYLASLRGHVAAVYQIAWSAD--SRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYA 461
Query: 704 VTVSPDGSLCASGGKDMXAMLW 769
V SPDG ASGGKD +W
Sbjct: 462 VDWSPDGQRVASGGKDKCLRIW 483
Score = 73.7 bits (173), Expect = 7e-13
Identities = 52/200 (26%), Positives = 100/200 (50%), Gaps = 4/200 (2%)
Frame = +2
Query: 200 MILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYAL-SGSWDK--- 367
++ S+S+D+T+ VW+ + G+ + L GH H+++ + LS+D YAL +G+++
Sbjct: 259 LLYSASQDRTIKVWRA-----HDGVLCRTLQGHGHWVNTMALSTD--YALRTGAFEPAEA 311
Query: 368 TLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDD 547
++ DL + + ++ ++ ++VSGS D T+ LW+ + K +
Sbjct: 312 SVNPQDLQG--SLQELKERALSRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMT 369
Query: 548 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 727
GH ++ V FSP+ + I+ S +D+++K+W K + GH + + S D
Sbjct: 370 GHQALINQVLFSPD--SRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSR 427
Query: 728 LCASGGKDMXAMLWDLNDGK 787
L SG D +WD+ K
Sbjct: 428 LLVSGSSDSTLKVWDVKAQK 447
Score = 65.3 bits (152), Expect = 2e-10
Identities = 57/223 (25%), Positives = 99/223 (44%), Gaps = 5/223 (2%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPD----MILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHF 307
TL GH+ W+T ++ P + + + SSS+D ++ +W T G ++ L GH+
Sbjct: 194 TLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTTA-----GRCERILTGHTQS 248
Query: 308 ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSR 487
++ + DG S S D+T+++W G R + H V ++A S D + +G+
Sbjct: 249 VTCLRWGGDG-LLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALSTDYA-LRTGAF 306
Query: 488 DKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLK 667
+ N + + ++Q+ +S +VS D T+ +W K
Sbjct: 307 EPAEASVNP-QDLQGSLQELKERA-LSRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKP 364
Query: 668 INHL-GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ + GH +N V SPD + AS D LWD GK+L
Sbjct: 365 LTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYL 407
Score = 62.9 bits (146), Expect = 1e-09
Identities = 45/159 (28%), Positives = 78/159 (49%), Gaps = 7/159 (4%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDV 319
T +GH WV I+ +P + S ++ +++W D + + L GHS +I+ +
Sbjct: 151 TCKGHRHWVLSISWSPD-GKKLASGCKNGQILLW----DPSTGKQVGRTLAGHSKWITGL 205
Query: 320 V-----LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGS 484
+ + Y S S D ++R+WD AG+ R HT+ V + + D + S S
Sbjct: 206 SWEPLHANPECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDG-LLYSAS 264
Query: 485 RDKTIKLWNTL--AECKYTIQDDGHSDWVSCVRFSPNHA 595
+D+TIK+W C+ T+Q GH WV+ + S ++A
Sbjct: 265 QDRTIKVWRAHDGVLCR-TLQ--GHGHWVNTMALSTDYA 300
Score = 56.4 bits (130), Expect = 1e-07
Identities = 38/139 (27%), Positives = 64/139 (46%), Gaps = 6/139 (4%)
Frame = +2
Query: 389 AAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVS 568
A + T E H++ V+SVAFS + + SGS D T++ W+ E + GH WV
Sbjct: 102 AVTRCTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPH-FTCKGHRHWVL 160
Query: 569 CVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL-GHSGYLNTVT-----VSPDGSL 730
+ +SP+ + C + + +W + K L GHS ++ ++ +P+
Sbjct: 161 SISWSPD-GKKLASGCK-NGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRY 218
Query: 731 CASGGKDMXAMLWDLNDGK 787
AS KD +WD G+
Sbjct: 219 VASSSKDGSVRIWDTTAGR 237
Score = 52.4 bits (120), Expect = 2e-06
Identities = 31/97 (31%), Positives = 48/97 (49%)
Frame = +2
Query: 503 LWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLG 682
++ A + T +GHS+ V V FSP + S D TV+ W L+ G
Sbjct: 97 IFRVRAVTRCTSSLEGHSEAVISVAFSPT--GKYLASGSGDTTVRFWDLSTETPHFTCKG 154
Query: 683 HSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
H ++ +++ SPDG ASG K+ +LWD + GK +
Sbjct: 155 HRHWVLSISWSPDGKKLASGCKNGQILLWDPSTGKQV 191
>AB209111-1|BAD92348.1| 487|Homo sapiens Notchless gene homolog
variant protein.
Length = 487
Score = 98.7 bits (235), Expect = 2e-20
Identities = 52/150 (34%), Positives = 81/150 (54%)
Frame = +2
Query: 194 PDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTL 373
P+ ++S S D TL +W D+ P R+ GH I+ V+ S D S S+DK++
Sbjct: 343 PERLVSGSDDFTLFLWSPAEDKK----PLTRMTGHQALINQVLFSPDSRIVASASFDKSI 398
Query: 374 RLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGH 553
+LWD GK H V +A+S D+R +VSGS D T+K+W+ A+ K + GH
Sbjct: 399 KLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQ-KLAMDLPGH 457
Query: 554 SDWVSCVRFSPNHANPIIVSCGWDRTVKVW 643
+D V V +SP+ + S G D+ +++W
Sbjct: 458 ADEVYAVDWSPDGQR--VASGGKDKCLRIW 485
Score = 89.4 bits (212), Expect = 1e-17
Identities = 52/169 (30%), Positives = 82/169 (48%), Gaps = 3/169 (1%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNR 466
L GHS + V S G Y SGS D T+R WDL+ + H VLS+++S D +
Sbjct: 112 LEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGK 171
Query: 467 QIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANP---IIVSCGWDRTVK 637
++ SG ++ I LW+ + GHS W++ + + P HANP + S D +V+
Sbjct: 172 KLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVR 231
Query: 638 VWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDG 784
+W T + + GH+ + + DG L S +D +W +DG
Sbjct: 232 IWDTTAGRCERILTGHTQSVTCLRWGGDG-LLYSASQDRTIKVWRAHDG 279
Score = 79.0 bits (186), Expect = 2e-14
Identities = 54/142 (38%), Positives = 73/142 (51%), Gaps = 1/142 (0%)
Frame = +2
Query: 347 LSGSWDKTLRLWDLAAGKTT-RRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAE 523
+SGS D TL LW A K R H + V FS D+R + S S DK+IKLW+
Sbjct: 347 VSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTG 406
Query: 524 CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNT 703
KY GH V + +S + + ++VS D T+KVW + KL ++ GH+ +
Sbjct: 407 -KYLASLRGHVAAVYQIAWSAD--SRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYA 463
Query: 704 VTVSPDGSLCASGGKDMXAMLW 769
V SPDG ASGGKD +W
Sbjct: 464 VDWSPDGQRVASGGKDKCLRIW 485
Score = 72.5 bits (170), Expect = 2e-12
Identities = 52/200 (26%), Positives = 99/200 (49%), Gaps = 4/200 (2%)
Frame = +2
Query: 200 MILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYAL-SGSWDK--- 367
++ S+S+D+T+ VW+ + G+ + L GH H+++ + LS+D YAL +G+++
Sbjct: 261 LLYSASQDRTIKVWRA-----HDGVLCRTLQGHGHWVNTMALSTD--YALRTGAFEPAEA 313
Query: 368 TLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDD 547
++ DL + ++ ++ ++VSGS D T+ LW+ + K +
Sbjct: 314 SVNPQDLQG--FLQELKERALSRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMT 371
Query: 548 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 727
GH ++ V FSP+ + I+ S +D+++K+W K + GH + + S D
Sbjct: 372 GHQALINQVLFSPD--SRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSR 429
Query: 728 LCASGGKDMXAMLWDLNDGK 787
L SG D +WD+ K
Sbjct: 430 LLVSGSSDSTLKVWDVKAQK 449
Score = 64.1 bits (149), Expect = 6e-10
Identities = 57/223 (25%), Positives = 98/223 (43%), Gaps = 5/223 (2%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPD----MILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHF 307
TL GH+ W+T ++ P + + + SSS+D ++ +W T G ++ L GH+
Sbjct: 196 TLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTTA-----GRCERILTGHTQS 250
Query: 308 ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSR 487
++ + DG S S D+T+++W G R + H V ++A S D + +G+
Sbjct: 251 VTCLRWGGDG-LLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALSTDYA-LRTGAF 308
Query: 488 DKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLK 667
+ N + + +Q+ +S +VS D T+ +W K
Sbjct: 309 EPAEASVNP-QDLQGFLQELKERA-LSRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKP 366
Query: 668 INHL-GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ + GH +N V SPD + AS D LWD GK+L
Sbjct: 367 LTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYL 409
Score = 62.9 bits (146), Expect = 1e-09
Identities = 45/159 (28%), Positives = 78/159 (49%), Gaps = 7/159 (4%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDV 319
T +GH WV I+ +P + S ++ +++W D + + L GHS +I+ +
Sbjct: 153 TCKGHRHWVLSISWSPD-GKKLASGCKNGQILLW----DPSTGKQVGRTLAGHSKWITGL 207
Query: 320 V-----LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGS 484
+ + Y S S D ++R+WD AG+ R HT+ V + + D + S S
Sbjct: 208 SWEPLHANPECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDG-LLYSAS 266
Query: 485 RDKTIKLWNTL--AECKYTIQDDGHSDWVSCVRFSPNHA 595
+D+TIK+W C+ T+Q GH WV+ + S ++A
Sbjct: 267 QDRTIKVWRAHDGVLCR-TLQ--GHGHWVNTMALSTDYA 302
Score = 56.4 bits (130), Expect = 1e-07
Identities = 38/139 (27%), Positives = 64/139 (46%), Gaps = 6/139 (4%)
Frame = +2
Query: 389 AAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVS 568
A + T E H++ V+SVAFS + + SGS D T++ W+ E + GH WV
Sbjct: 104 AVTRCTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPH-FTCKGHRHWVL 162
Query: 569 CVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL-GHSGYLNTVT-----VSPDGSL 730
+ +SP+ + C + + +W + K L GHS ++ ++ +P+
Sbjct: 163 SISWSPD-GKKLASGCK-NGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRY 220
Query: 731 CASGGKDMXAMLWDLNDGK 787
AS KD +WD G+
Sbjct: 221 VASSSKDGSVRIWDTTAGR 239
Score = 52.4 bits (120), Expect = 2e-06
Identities = 31/97 (31%), Positives = 48/97 (49%)
Frame = +2
Query: 503 LWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLG 682
++ A + T +GHS+ V V FSP + S D TV+ W L+ G
Sbjct: 99 IFRVRAVTRCTSSLEGHSEAVISVAFSPT--GKYLASGSGDTTVRFWDLSTETPHFTCKG 156
Query: 683 HSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
H ++ +++ SPDG ASG K+ +LWD + GK +
Sbjct: 157 HRHWVLSISWSPDGKKLASGCKNGQILLWDPSTGKQV 193
>X95525-1|CAA64777.1| 799|Homo sapiens hTAFII100 protein.
Length = 799
Score = 98.3 bits (234), Expect = 3e-20
Identities = 59/168 (35%), Positives = 80/168 (47%)
Frame = +2
Query: 281 KRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVD 460
K LYGHS + S D NY LS S D T+RLW L ++ H V FS
Sbjct: 537 KILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPY 596
Query: 461 NRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKV 640
VSG D+ +LW T I GH V+C RF PN + + + DRTV++
Sbjct: 597 GYYFVSGGHDRVARLWATDHYQPLRI-FAGHLADVNCTRFHPN--SNYVATGSADRTVRL 653
Query: 641 WHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDG 784
W + N GH G ++++T SP+G A+G D +LWD+ G
Sbjct: 654 WDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHG 701
Score = 87.4 bits (207), Expect = 5e-17
Identities = 62/211 (29%), Positives = 96/211 (45%), Gaps = 1/211 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH+G V + +P + +LSSS D T+ +W L G GH++ + D
Sbjct: 539 LYGHSGPVYGASFSPDR-NYLLSSSEDGTVRLWSLQTFTCLVGYK-----GHNYPVWDTQ 592
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
S G Y +SG D+ RLW + R F H DV F ++ + +GS D+T++
Sbjct: 593 FSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVR 652
Query: 503 LWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
LW+ L C GH + + FSPN + + D V +W + + +
Sbjct: 653 LWDVLNGNCVRIFT--GHKGPIHSLTFSPN--GRFLATGATDGRVLLWDIGHGLMVGELK 708
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
GH+ + ++ S DG + ASG D LWD
Sbjct: 709 GHTDTVCSLRFSRDGEILASGSMDNTVRLWD 739
Score = 58.4 bits (135), Expect = 3e-08
Identities = 32/115 (27%), Positives = 54/115 (46%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLW 382
+ + S D+T+ +W + G + GH I + S +G + +G+ D + LW
Sbjct: 642 VATGSADRTVRLWDVLN-----GNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLW 696
Query: 383 DLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDD 547
D+ G + HT V S+ FS D + SGS D T++LW+ + + DD
Sbjct: 697 DIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAIKAFEDLETDD 751
Score = 42.7 bits (96), Expect = 0.001
Identities = 25/112 (22%), Positives = 50/112 (44%)
Frame = +2
Query: 149 GHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLS 328
GH G + + +P + + + D +++W + +G+ L GH+ + + S
Sbjct: 667 GHKGPIHSLTFSPN-GRFLATGATDGRVLLWDI-----GHGLMVGELKGHTDTVCSLRFS 720
Query: 329 SDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGS 484
DG SGS D T+RLWD +D T + ++++++ G+
Sbjct: 721 RDGEILASGSMDNTVRLWDAIKAFEDLETDDFTTATGHINLPENSQELLLGT 772
>U80191-1|AAC51215.1| 800|Homo sapiens TFIID subunit TAFII100
protein.
Length = 800
Score = 98.3 bits (234), Expect = 3e-20
Identities = 59/168 (35%), Positives = 80/168 (47%)
Frame = +2
Query: 281 KRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVD 460
K LYGHS + S D NY LS S D T+RLW L ++ H V FS
Sbjct: 537 KILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPY 596
Query: 461 NRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKV 640
VSG D+ +LW T I GH V+C RF PN + + + DRTV++
Sbjct: 597 GYYFVSGGHDRVARLWATDHYQPLRI-FAGHLADVNCTRFHPN--SNYVATGSADRTVRL 653
Query: 641 WHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDG 784
W + N GH G ++++T SP+G A+G D +LWD+ G
Sbjct: 654 WDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHG 701
Score = 87.4 bits (207), Expect = 5e-17
Identities = 62/211 (29%), Positives = 96/211 (45%), Gaps = 1/211 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH+G V + +P + +LSSS D T+ +W L G GH++ + D
Sbjct: 539 LYGHSGPVYGASFSPDR-NYLLSSSEDGTVRLWSLQTFTCLVGYK-----GHNYPVWDTQ 592
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
S G Y +SG D+ RLW + R F H DV F ++ + +GS D+T++
Sbjct: 593 FSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVR 652
Query: 503 LWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
LW+ L C GH + + FSPN + + D V +W + + +
Sbjct: 653 LWDVLNGNCVRIFT--GHKGPIHSLTFSPN--GRFLATGATDGRVLLWDIGHGLMVGELK 708
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
GH+ + ++ S DG + ASG D LWD
Sbjct: 709 GHTDTVCSLRFSRDGEILASGSMDNTVRLWD 739
Score = 58.4 bits (135), Expect = 3e-08
Identities = 32/115 (27%), Positives = 54/115 (46%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLW 382
+ + S D+T+ +W + G + GH I + S +G + +G+ D + LW
Sbjct: 642 VATGSADRTVRLWDVLN-----GNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLW 696
Query: 383 DLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDD 547
D+ G + HT V S+ FS D + SGS D T++LW+ + + DD
Sbjct: 697 DIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAIKAFEDLETDD 751
Score = 42.7 bits (96), Expect = 0.001
Identities = 25/112 (22%), Positives = 50/112 (44%)
Frame = +2
Query: 149 GHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLS 328
GH G + + +P + + + D +++W + +G+ L GH+ + + S
Sbjct: 667 GHKGPIHSLTFSPN-GRFLATGATDGRVLLWDI-----GHGLMVGELKGHTDTVCSLRFS 720
Query: 329 SDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGS 484
DG SGS D T+RLWD +D T + ++++++ G+
Sbjct: 721 RDGEILASGSMDNTVRLWDAIKAFEDLETDDFTTATGHINLPENSQELLLGT 772
>U75309-1|AAC50902.1| 801|Homo sapiens TBP-associated factor protein.
Length = 801
Score = 98.3 bits (234), Expect = 3e-20
Identities = 59/168 (35%), Positives = 80/168 (47%)
Frame = +2
Query: 281 KRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVD 460
K LYGHS + S D NY LS S D T+RLW L ++ H V FS
Sbjct: 538 KILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPY 597
Query: 461 NRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKV 640
VSG D+ +LW T I GH V+C RF PN + + + DRTV++
Sbjct: 598 GYYFVSGGHDRVARLWATDHYQPLRI-FAGHLADVNCTRFHPN--SNYVATGSADRTVRL 654
Query: 641 WHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDG 784
W + N GH G ++++T SP+G A+G D +LWD+ G
Sbjct: 655 WDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHG 702
Score = 87.4 bits (207), Expect = 5e-17
Identities = 62/211 (29%), Positives = 96/211 (45%), Gaps = 1/211 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH+G V + +P + +LSSS D T+ +W L G GH++ + D
Sbjct: 540 LYGHSGPVYGASFSPDR-NYLLSSSEDGTVRLWSLQTFTCLVGYK-----GHNYPVWDTQ 593
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
S G Y +SG D+ RLW + R F H DV F ++ + +GS D+T++
Sbjct: 594 FSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVR 653
Query: 503 LWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
LW+ L C GH + + FSPN + + D V +W + + +
Sbjct: 654 LWDVLNGNCVRIFT--GHKGPIHSLTFSPN--GRFLATGATDGRVLLWDIGHGLMVGELK 709
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
GH+ + ++ S DG + ASG D LWD
Sbjct: 710 GHTDTVCSLRFSRDGEILASGSMDNTVRLWD 740
Score = 58.4 bits (135), Expect = 3e-08
Identities = 32/115 (27%), Positives = 54/115 (46%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLW 382
+ + S D+T+ +W + G + GH I + S +G + +G+ D + LW
Sbjct: 643 VATGSADRTVRLWDVLN-----GNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLW 697
Query: 383 DLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDD 547
D+ G + HT V S+ FS D + SGS D T++LW+ + + DD
Sbjct: 698 DIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAIKAFEDLETDD 752
Score = 42.7 bits (96), Expect = 0.001
Identities = 25/112 (22%), Positives = 50/112 (44%)
Frame = +2
Query: 149 GHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLS 328
GH G + + +P + + + D +++W + +G+ L GH+ + + S
Sbjct: 668 GHKGPIHSLTFSPN-GRFLATGATDGRVLLWDI-----GHGLMVGELKGHTDTVCSLRFS 721
Query: 329 SDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGS 484
DG SGS D T+RLWD +D T + ++++++ G+
Sbjct: 722 RDGEILASGSMDNTVRLWDAIKAFEDLETDDFTTATGHINLPENSQELLLGT 773
>BC052268-1|AAH52268.2| 800|Homo sapiens TAF5 RNA polymerase II, TATA
box binding protein (TBP)-associated factor, 100kD
protein.
Length = 800
Score = 98.3 bits (234), Expect = 3e-20
Identities = 59/168 (35%), Positives = 80/168 (47%)
Frame = +2
Query: 281 KRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVD 460
K LYGHS + S D NY LS S D T+RLW L ++ H V FS
Sbjct: 537 KILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPY 596
Query: 461 NRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKV 640
VSG D+ +LW T I GH V+C RF PN + + + DRTV++
Sbjct: 597 GYYFVSGGHDRVARLWATDHYQPLRI-FAGHLADVNCTRFHPN--SNYVATGSADRTVRL 653
Query: 641 WHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDG 784
W + N GH G ++++T SP+G A+G D +LWD+ G
Sbjct: 654 WDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHG 701
Score = 87.4 bits (207), Expect = 5e-17
Identities = 62/211 (29%), Positives = 96/211 (45%), Gaps = 1/211 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH+G V + +P + +LSSS D T+ +W L G GH++ + D
Sbjct: 539 LYGHSGPVYGASFSPDR-NYLLSSSEDGTVRLWSLQTFTCLVGYK-----GHNYPVWDTQ 592
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
S G Y +SG D+ RLW + R F H DV F ++ + +GS D+T++
Sbjct: 593 FSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVR 652
Query: 503 LWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
LW+ L C GH + + FSPN + + D V +W + + +
Sbjct: 653 LWDVLNGNCVRIFT--GHKGPIHSLTFSPN--GRFLATGATDGRVLLWDIGHGLMVGELK 708
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
GH+ + ++ S DG + ASG D LWD
Sbjct: 709 GHTDTVCSLRFSRDGEILASGSMDNTVRLWD 739
Score = 58.4 bits (135), Expect = 3e-08
Identities = 32/115 (27%), Positives = 54/115 (46%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLW 382
+ + S D+T+ +W + G + GH I + S +G + +G+ D + LW
Sbjct: 642 VATGSADRTVRLWDVLN-----GNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLW 696
Query: 383 DLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDD 547
D+ G + HT V S+ FS D + SGS D T++LW+ + + DD
Sbjct: 697 DIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAIKAFEDLETDD 751
Score = 42.7 bits (96), Expect = 0.001
Identities = 25/112 (22%), Positives = 50/112 (44%)
Frame = +2
Query: 149 GHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLS 328
GH G + + +P + + + D +++W + +G+ L GH+ + + S
Sbjct: 667 GHKGPIHSLTFSPN-GRFLATGATDGRVLLWDI-----GHGLMVGELKGHTDTVCSLRFS 720
Query: 329 SDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGS 484
DG SGS D T+RLWD +D T + ++++++ G+
Sbjct: 721 RDGEILASGSMDNTVRLWDAIKAFEDLETDDFTTATGHINLPENSQELLLGT 772
>AL591408-4|CAI16747.1| 800|Homo sapiens TAF5 RNA polymerase II, TATA
box binding protein (TBP)-associated factor, 100kD
protein.
Length = 800
Score = 98.3 bits (234), Expect = 3e-20
Identities = 59/168 (35%), Positives = 80/168 (47%)
Frame = +2
Query: 281 KRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVD 460
K LYGHS + S D NY LS S D T+RLW L ++ H V FS
Sbjct: 537 KILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPY 596
Query: 461 NRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKV 640
VSG D+ +LW T I GH V+C RF PN + + + DRTV++
Sbjct: 597 GYYFVSGGHDRVARLWATDHYQPLRI-FAGHLADVNCTRFHPN--SNYVATGSADRTVRL 653
Query: 641 WHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDG 784
W + N GH G ++++T SP+G A+G D +LWD+ G
Sbjct: 654 WDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHG 701
Score = 87.4 bits (207), Expect = 5e-17
Identities = 62/211 (29%), Positives = 96/211 (45%), Gaps = 1/211 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH+G V + +P + +LSSS D T+ +W L G GH++ + D
Sbjct: 539 LYGHSGPVYGASFSPDR-NYLLSSSEDGTVRLWSLQTFTCLVGYK-----GHNYPVWDTQ 592
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
S G Y +SG D+ RLW + R F H DV F ++ + +GS D+T++
Sbjct: 593 FSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVR 652
Query: 503 LWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
LW+ L C GH + + FSPN + + D V +W + + +
Sbjct: 653 LWDVLNGNCVRIFT--GHKGPIHSLTFSPN--GRFLATGATDGRVLLWDIGHGLMVGELK 708
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
GH+ + ++ S DG + ASG D LWD
Sbjct: 709 GHTDTVCSLRFSRDGEILASGSMDNTVRLWD 739
Score = 58.4 bits (135), Expect = 3e-08
Identities = 32/115 (27%), Positives = 54/115 (46%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLW 382
+ + S D+T+ +W + G + GH I + S +G + +G+ D + LW
Sbjct: 642 VATGSADRTVRLWDVLN-----GNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLW 696
Query: 383 DLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDD 547
D+ G + HT V S+ FS D + SGS D T++LW+ + + DD
Sbjct: 697 DIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAIKAFEDLETDD 751
Score = 42.7 bits (96), Expect = 0.001
Identities = 25/112 (22%), Positives = 50/112 (44%)
Frame = +2
Query: 149 GHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLS 328
GH G + + +P + + + D +++W + +G+ L GH+ + + S
Sbjct: 667 GHKGPIHSLTFSPN-GRFLATGATDGRVLLWDI-----GHGLMVGELKGHTDTVCSLRFS 720
Query: 329 SDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGS 484
DG SGS D T+RLWD +D T + ++++++ G+
Sbjct: 721 RDGEILASGSMDNTVRLWDAIKAFEDLETDDFTTATGHINLPENSQELLLGT 772
>AK223615-1|BAD97335.1| 803|Homo sapiens Transcription initiation
factor TFIID subunit 5 variant protein.
Length = 803
Score = 98.3 bits (234), Expect = 3e-20
Identities = 59/168 (35%), Positives = 80/168 (47%)
Frame = +2
Query: 281 KRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVD 460
K LYGHS + S D NY LS S D T+RLW L ++ H V FS
Sbjct: 540 KILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPY 599
Query: 461 NRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKV 640
VSG D+ +LW T I GH V+C RF PN + + + DRTV++
Sbjct: 600 GYYFVSGGHDRVARLWATDHYQPLRI-FAGHLADVNCTRFHPN--SNYVATGSADRTVRL 656
Query: 641 WHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDG 784
W + N GH G ++++T SP+G A+G D +LWD+ G
Sbjct: 657 WDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHG 704
Score = 87.4 bits (207), Expect = 5e-17
Identities = 62/211 (29%), Positives = 96/211 (45%), Gaps = 1/211 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH+G V + +P + +LSSS D T+ +W L G GH++ + D
Sbjct: 542 LYGHSGPVYGASFSPDR-NYLLSSSEDGTVRLWSLQTFTCLVGYK-----GHNYPVWDTQ 595
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
S G Y +SG D+ RLW + R F H DV F ++ + +GS D+T++
Sbjct: 596 FSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVR 655
Query: 503 LWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
LW+ L C GH + + FSPN + + D V +W + + +
Sbjct: 656 LWDVLNGNCVRIFT--GHKGPIHSLTFSPN--GRFLATGATDGRVLLWDIGHGLMVGELK 711
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
GH+ + ++ S DG + ASG D LWD
Sbjct: 712 GHTDTVCSLRFSRDGEILASGSMDNTVRLWD 742
Score = 58.4 bits (135), Expect = 3e-08
Identities = 32/115 (27%), Positives = 54/115 (46%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLW 382
+ + S D+T+ +W + G + GH I + S +G + +G+ D + LW
Sbjct: 645 VATGSADRTVRLWDVLN-----GNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLW 699
Query: 383 DLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDD 547
D+ G + HT V S+ FS D + SGS D T++LW+ + + DD
Sbjct: 700 DIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAIKAFEDLETDD 754
Score = 42.7 bits (96), Expect = 0.001
Identities = 25/112 (22%), Positives = 50/112 (44%)
Frame = +2
Query: 149 GHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLS 328
GH G + + +P + + + D +++W + +G+ L GH+ + + S
Sbjct: 670 GHKGPIHSLTFSPN-GRFLATGATDGRVLLWDI-----GHGLMVGELKGHTDTVCSLRFS 723
Query: 329 SDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGS 484
DG SGS D T+RLWD +D T + ++++++ G+
Sbjct: 724 RDGEILASGSMDNTVRLWDAIKAFEDLETDDFTTATGHINLPENSQELLLGT 775
>AF090988-1|AAC69625.1| 357|Homo sapiens U5 snRNP-specific 40 kDa
protein protein.
Length = 357
Score = 98.3 bits (234), Expect = 3e-20
Identities = 66/212 (31%), Positives = 105/212 (49%), Gaps = 1/212 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH G V +P + S+ D+ +++W + D +NY L GHS + ++
Sbjct: 62 LSGHEGEVYCCKFHPN-GSTLASAGFDRLILLWNVYGDCDNYAT----LKGHSGAVMELH 116
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV-SGSRDKTI 499
++DG+ S S DKT+ +WD G+ +R + HT V S + + Q+V +GS D T+
Sbjct: 117 YNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARKSPQLVCTGSDDGTV 176
Query: 500 KLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
KLW+ K IQ ++ V V F N + I+S G D +KVW L KL
Sbjct: 177 KLWD--IRKKAAIQTFQNTYQVLAVTF--NDTSDQIISGGIDNDIKVWDLRQNKLTYTMR 232
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
GH+ + +++S +GS S D +WD+
Sbjct: 233 GHADSVTGLSLSSEGSYLLSNAMDNTVRVWDV 264
Score = 93.9 bits (223), Expect = 6e-19
Identities = 71/228 (31%), Positives = 112/228 (49%), Gaps = 9/228 (3%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDV 319
TL+GH+G V ++ N M+ S+S DKT+ VW ++ G KRL GH+ F++
Sbjct: 104 TLKGHSGAVMELHYNTD-GSMLFSASTDKTVAVW-----DSETGERVKRLKGHTSFVNSC 157
Query: 320 VLSSDG-NYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKT 496
+ +GS D T++LWD+ + F++ T VL+V F+ + QI+SG D
Sbjct: 158 YPARKSPQLVCTGSDDGTVKLWDIRKKAAIQTFQN-TYQVLAVTFNDTSDQIISGGIDND 216
Query: 497 IKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT------NC 658
IK+W+ L + K T GH+D V+ + S + ++S D TV+VW + C
Sbjct: 217 IKVWD-LRQNKLTYTMRGHADSVTGLSLSSEGS--YLLSNAMDNTVRVWDVRPFAPKERC 273
Query: 659 KLKINHLGHSGYLNTVTVS--PDGSLCASGGKDMXAMLWDLNDGKHLH 796
H+ N + S PDGS A+G D +WD + L+
Sbjct: 274 VKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILY 321
Score = 76.2 bits (179), Expect = 1e-13
Identities = 50/217 (23%), Positives = 94/217 (43%), Gaps = 5/217 (2%)
Frame = +2
Query: 116 SETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
SET + L+GH +V K P ++ + S D T+ +W + + + +
Sbjct: 138 SETGERVKRLKGHTSFVNSCYPARKSPQLVCTGSDDGTVKLWDIRKKA------AIQTFQ 191
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
+++ + V + + +SG D +++WDL K T H V ++ S + ++
Sbjct: 192 NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLL 251
Query: 476 SGSRDKTIKLWNTLA-----ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKV 640
S + D T+++W+ C Q + H+ + +R S + I + DR V V
Sbjct: 252 SNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYV 311
Query: 641 WHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKD 751
W T+ ++ GH+G +N V PD + S D
Sbjct: 312 WDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSD 348
Score = 50.0 bits (114), Expect = 1e-05
Identities = 35/127 (27%), Positives = 59/127 (46%), Gaps = 3/127 (2%)
Frame = +2
Query: 128 KLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKL---TRDENNYGIPQKRLYGH 298
KL T+RGH VT ++ + + +LS++ D T+ VW + E I Q ++
Sbjct: 226 KLTYTMRGHADSVTGLSLSSE-GSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNF 284
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVS 478
+ S DG+ +GS D+ + +WD + + + H + VAF D I+S
Sbjct: 285 EKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIIS 344
Query: 479 GSRDKTI 499
S DK +
Sbjct: 345 ASSDKRL 351
Score = 49.2 bits (112), Expect = 2e-05
Identities = 25/83 (30%), Positives = 41/83 (49%), Gaps = 1/83 (1%)
Frame = +2
Query: 548 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT-NCKLKINHLGHSGYLNTVTVSPDG 724
GH V C +F PN + + S G+DR + +W++ +C GHSG + + + DG
Sbjct: 64 GHEGEVYCCKFHPNGST--LASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDG 121
Query: 725 SLCASGGKDMXAMLWDLNDGKHL 793
S+ S D +WD G+ +
Sbjct: 122 SMLFSASTDKTVAVWDSETGERV 144
>EF011621-1|ABK41111.1| 357|Homo sapiens CDW11/WDR57 protein.
Length = 357
Score = 97.5 bits (232), Expect = 5e-20
Identities = 66/212 (31%), Positives = 104/212 (49%), Gaps = 1/212 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH G V +P + S+ D+ +++W + D +NY L GHS + ++
Sbjct: 62 LSGHEGEVYCCKFHPN-GSTLASAGFDRLILLWNVYGDCDNYAT----LKGHSGAVMELH 116
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV-SGSRDKTI 499
++DG+ S S DKT+ +WD G+ +R + HT V S + Q+V +GS D T+
Sbjct: 117 YNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTV 176
Query: 500 KLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
KLW+ K IQ ++ V V F N + I+S G D +KVW L KL
Sbjct: 177 KLWD--IRKKAAIQTFQNTYQVLAVTF--NDTSDQIISGGIDNDIKVWDLRQNKLTYTMR 232
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
GH+ + +++S +GS S D +WD+
Sbjct: 233 GHADSVTGLSLSSEGSYLLSNAMDNTVRVWDV 264
Score = 95.9 bits (228), Expect = 1e-19
Identities = 72/228 (31%), Positives = 113/228 (49%), Gaps = 9/228 (3%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDV 319
TL+GH+G V ++ N M+ S+S DKT+ VW ++ G KRL GH+ F++
Sbjct: 104 TLKGHSGAVMELHYNTD-GSMLFSASTDKTVAVW-----DSETGERVKRLKGHTSFVNSC 157
Query: 320 VLSSDG-NYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKT 496
+ G +GS D T++LWD+ + F++ T VL+V F+ + QI+SG D
Sbjct: 158 YPARRGPQLVCTGSDDGTVKLWDIRKKAAIQTFQN-TYQVLAVTFNDTSDQIISGGIDND 216
Query: 497 IKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT------NC 658
IK+W+ L + K T GH+D V+ + S + ++S D TV+VW + C
Sbjct: 217 IKVWD-LRQNKLTYTMRGHADSVTGLSLSSEGS--YLLSNAMDNTVRVWDVRPFAPKERC 273
Query: 659 KLKINHLGHSGYLNTVTVS--PDGSLCASGGKDMXAMLWDLNDGKHLH 796
H+ N + S PDGS A+G D +WD + L+
Sbjct: 274 VKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILY 321
Score = 74.5 bits (175), Expect = 4e-13
Identities = 49/217 (22%), Positives = 94/217 (43%), Gaps = 5/217 (2%)
Frame = +2
Query: 116 SETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
SET + L+GH +V + P ++ + S D T+ +W + + + +
Sbjct: 138 SETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKA------AIQTFQ 191
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
+++ + V + + +SG D +++WDL K T H V ++ S + ++
Sbjct: 192 NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLL 251
Query: 476 SGSRDKTIKLWNT-----LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKV 640
S + D T+++W+ C Q + H+ + +R S + I + DR V V
Sbjct: 252 SNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYV 311
Query: 641 WHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKD 751
W T+ ++ GH+G +N V PD + S D
Sbjct: 312 WDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSD 348
Score = 50.0 bits (114), Expect = 1e-05
Identities = 35/127 (27%), Positives = 59/127 (46%), Gaps = 3/127 (2%)
Frame = +2
Query: 128 KLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKL---TRDENNYGIPQKRLYGH 298
KL T+RGH VT ++ + + +LS++ D T+ VW + E I Q ++
Sbjct: 226 KLTYTMRGHADSVTGLSLSSE-GSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNF 284
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVS 478
+ S DG+ +GS D+ + +WD + + + H + VAF D I+S
Sbjct: 285 EKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIIS 344
Query: 479 GSRDKTI 499
S DK +
Sbjct: 345 ASSDKRL 351
Score = 49.2 bits (112), Expect = 2e-05
Identities = 25/83 (30%), Positives = 41/83 (49%), Gaps = 1/83 (1%)
Frame = +2
Query: 548 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT-NCKLKINHLGHSGYLNTVTVSPDG 724
GH V C +F PN + + S G+DR + +W++ +C GHSG + + + DG
Sbjct: 64 GHEGEVYCCKFHPNGST--LASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDG 121
Query: 725 SLCASGGKDMXAMLWDLNDGKHL 793
S+ S D +WD G+ +
Sbjct: 122 SMLFSASTDKTVAVWDSETGERV 144
>BC001494-1|AAH01494.1| 357|Homo sapiens WD repeat domain 57 (U5
snRNP specific) protein.
Length = 357
Score = 97.5 bits (232), Expect = 5e-20
Identities = 66/212 (31%), Positives = 104/212 (49%), Gaps = 1/212 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH G V +P + S+ D+ +++W + D +NY L GHS + ++
Sbjct: 62 LSGHEGEVYCCKFHPN-GSTLASAGFDRLILLWNVYGDCDNYAT----LKGHSGAVMELH 116
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV-SGSRDKTI 499
++DG+ S S DKT+ +WD G+ +R + HT V S + Q+V +GS D T+
Sbjct: 117 YNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTV 176
Query: 500 KLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
KLW+ K IQ ++ V V F N + I+S G D +KVW L KL
Sbjct: 177 KLWD--IRKKAAIQTFQNTYQVLAVTF--NDTSDQIISGGIDNDIKVWDLRQNKLTYTMR 232
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
GH+ + +++S +GS S D +WD+
Sbjct: 233 GHADSVTGLSLSSEGSYLLSNAMDNTVRVWDV 264
Score = 95.9 bits (228), Expect = 1e-19
Identities = 72/228 (31%), Positives = 113/228 (49%), Gaps = 9/228 (3%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDV 319
TL+GH+G V ++ N M+ S+S DKT+ VW ++ G KRL GH+ F++
Sbjct: 104 TLKGHSGAVMELHYNTD-GSMLFSASTDKTVAVW-----DSETGERVKRLKGHTSFVNSC 157
Query: 320 VLSSDG-NYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKT 496
+ G +GS D T++LWD+ + F++ T VL+V F+ + QI+SG D
Sbjct: 158 YPARRGPQLVCTGSDDGTVKLWDIRKKAAIQTFQN-TYQVLAVTFNDTSDQIISGGIDND 216
Query: 497 IKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT------NC 658
IK+W+ L + K T GH+D V+ + S + ++S D TV+VW + C
Sbjct: 217 IKVWD-LRQNKLTYTMRGHADSVTGLSLSSEGS--YLLSNAMDNTVRVWDVRPFAPKERC 273
Query: 659 KLKINHLGHSGYLNTVTVS--PDGSLCASGGKDMXAMLWDLNDGKHLH 796
H+ N + S PDGS A+G D +WD + L+
Sbjct: 274 VKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILY 321
Score = 74.5 bits (175), Expect = 4e-13
Identities = 49/217 (22%), Positives = 94/217 (43%), Gaps = 5/217 (2%)
Frame = +2
Query: 116 SETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
SET + L+GH +V + P ++ + S D T+ +W + + + +
Sbjct: 138 SETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKA------AIQTFQ 191
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
+++ + V + + +SG D +++WDL K T H V ++ S + ++
Sbjct: 192 NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLL 251
Query: 476 SGSRDKTIKLWNT-----LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKV 640
S + D T+++W+ C Q + H+ + +R S + I + DR V V
Sbjct: 252 SNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYV 311
Query: 641 WHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKD 751
W T+ ++ GH+G +N V PD + S D
Sbjct: 312 WDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSD 348
Score = 50.0 bits (114), Expect = 1e-05
Identities = 35/127 (27%), Positives = 59/127 (46%), Gaps = 3/127 (2%)
Frame = +2
Query: 128 KLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKL---TRDENNYGIPQKRLYGH 298
KL T+RGH VT ++ + + +LS++ D T+ VW + E I Q ++
Sbjct: 226 KLTYTMRGHADSVTGLSLSSE-GSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNF 284
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVS 478
+ S DG+ +GS D+ + +WD + + + H + VAF D I+S
Sbjct: 285 EKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIIS 344
Query: 479 GSRDKTI 499
S DK +
Sbjct: 345 ASSDKRL 351
Score = 49.2 bits (112), Expect = 2e-05
Identities = 25/83 (30%), Positives = 41/83 (49%), Gaps = 1/83 (1%)
Frame = +2
Query: 548 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT-NCKLKINHLGHSGYLNTVTVSPDG 724
GH V C +F PN + + S G+DR + +W++ +C GHSG + + + DG
Sbjct: 64 GHEGEVYCCKFHPNGST--LASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDG 121
Query: 725 SLCASGGKDMXAMLWDLNDGKHL 793
S+ S D +WD G+ +
Sbjct: 122 SMLFSASTDKTVAVWDSETGERV 144
>AL451070-1|CAH71848.1| 357|Homo sapiens WD repeat domain 57 (U5
snRNP specific) protein.
Length = 357
Score = 97.5 bits (232), Expect = 5e-20
Identities = 66/212 (31%), Positives = 104/212 (49%), Gaps = 1/212 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH G V +P + S+ D+ +++W + D +NY L GHS + ++
Sbjct: 62 LSGHEGEVYCCKFHPN-GSTLASAGFDRLILLWNVYGDCDNYAT----LKGHSGAVMELH 116
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV-SGSRDKTI 499
++DG+ S S DKT+ +WD G+ +R + HT V S + Q+V +GS D T+
Sbjct: 117 YNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTV 176
Query: 500 KLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
KLW+ K IQ ++ V V F N + I+S G D +KVW L KL
Sbjct: 177 KLWD--IRKKAAIQTFQNTYQVLAVTF--NDTSDQIISGGIDNDIKVWDLRQNKLTYTMR 232
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
GH+ + +++S +GS S D +WD+
Sbjct: 233 GHADSVTGLSLSSEGSYLLSNAMDNTVRVWDV 264
Score = 95.9 bits (228), Expect = 1e-19
Identities = 72/228 (31%), Positives = 113/228 (49%), Gaps = 9/228 (3%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDV 319
TL+GH+G V ++ N M+ S+S DKT+ VW ++ G KRL GH+ F++
Sbjct: 104 TLKGHSGAVMELHYNTD-GSMLFSASTDKTVAVW-----DSETGERVKRLKGHTSFVNSC 157
Query: 320 VLSSDG-NYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKT 496
+ G +GS D T++LWD+ + F++ T VL+V F+ + QI+SG D
Sbjct: 158 YPARRGPQLVCTGSDDGTVKLWDIRKKAAIQTFQN-TYQVLAVTFNDTSDQIISGGIDND 216
Query: 497 IKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT------NC 658
IK+W+ L + K T GH+D V+ + S + ++S D TV+VW + C
Sbjct: 217 IKVWD-LRQNKLTYTMRGHADSVTGLSLSSEGS--YLLSNAMDNTVRVWDVRPFAPKERC 273
Query: 659 KLKINHLGHSGYLNTVTVS--PDGSLCASGGKDMXAMLWDLNDGKHLH 796
H+ N + S PDGS A+G D +WD + L+
Sbjct: 274 VKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILY 321
Score = 74.5 bits (175), Expect = 4e-13
Identities = 49/217 (22%), Positives = 94/217 (43%), Gaps = 5/217 (2%)
Frame = +2
Query: 116 SETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
SET + L+GH +V + P ++ + S D T+ +W + + + +
Sbjct: 138 SETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKA------AIQTFQ 191
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
+++ + V + + +SG D +++WDL K T H V ++ S + ++
Sbjct: 192 NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLL 251
Query: 476 SGSRDKTIKLWNT-----LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKV 640
S + D T+++W+ C Q + H+ + +R S + I + DR V V
Sbjct: 252 SNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYV 311
Query: 641 WHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKD 751
W T+ ++ GH+G +N V PD + S D
Sbjct: 312 WDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSD 348
Score = 50.0 bits (114), Expect = 1e-05
Identities = 35/127 (27%), Positives = 59/127 (46%), Gaps = 3/127 (2%)
Frame = +2
Query: 128 KLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKL---TRDENNYGIPQKRLYGH 298
KL T+RGH VT ++ + + +LS++ D T+ VW + E I Q ++
Sbjct: 226 KLTYTMRGHADSVTGLSLSSE-GSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNF 284
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVS 478
+ S DG+ +GS D+ + +WD + + + H + VAF D I+S
Sbjct: 285 EKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIIS 344
Query: 479 GSRDKTI 499
S DK +
Sbjct: 345 ASSDKRL 351
Score = 49.2 bits (112), Expect = 2e-05
Identities = 25/83 (30%), Positives = 41/83 (49%), Gaps = 1/83 (1%)
Frame = +2
Query: 548 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT-NCKLKINHLGHSGYLNTVTVSPDG 724
GH V C +F PN + + S G+DR + +W++ +C GHSG + + + DG
Sbjct: 64 GHEGEVYCCKFHPNGST--LASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDG 121
Query: 725 SLCASGGKDMXAMLWDLNDGKHL 793
S+ S D +WD G+ +
Sbjct: 122 SMLFSASTDKTVAVWDSETGERV 144
>AF001687-1|AAB87640.1| 521|Homo sapiens U4/U6 snRNP 60 kDa protein
protein.
Length = 521
Score = 97.5 bits (232), Expect = 5e-20
Identities = 63/212 (29%), Positives = 100/212 (47%), Gaps = 1/212 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
+ GH V ++ +P + ++ D++ +W L E + Q+ GHS + D+
Sbjct: 318 IEGHTVRVARVMWHPS-GRFLGTTCYDRSWRLWDLEAQEEI--LHQE---GHSMGVYDIA 371
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
DG+ A +G D R+WDL G+ EDH K++ + FS + I +GS D T K
Sbjct: 372 FHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEDHLKEIYGINFSPNGYHIATGSGDNTCK 431
Query: 503 LWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
+W+ C YTI H + V+ V+F P H N +++ +D T K+W
Sbjct: 432 VWDLRQRRCVYTIPP--HQNLVTGVKFEPIHGN-FLLTGAYDNTAKIWTHPGWSPLKTLA 488
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
GH G + + +S DG L A+ D LW L
Sbjct: 489 GHEGKVMGLDISSDGQLIATYSYDRTFKLWML 520
Score = 73.3 bits (172), Expect = 9e-13
Identities = 61/219 (27%), Positives = 96/219 (43%), Gaps = 9/219 (4%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYP------DMILSS-SRDKTLIVWKLTRDENNYGIPQKRLYGH 298
TLRGHN V I +PK D+ L+S + D ++ +W L DE P + GH
Sbjct: 267 TLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDE-----PVADIEGH 321
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVS 478
+ ++ V+ G + + +D++ RLWDL A + E H+ V +AF D +
Sbjct: 322 TVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGT 381
Query: 479 GSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 655
G D ++W+ C ++D H + + FSPN + I + D T KVW L
Sbjct: 382 GGLDAFGRVWDLRTGRCIMFLED--HLKEIYGINFSPNGYH--IATGSGDNTCKVWDLRQ 437
Query: 656 CKLKINHLGHSGYLNTVTVSP-DGSLCASGGKDMXAMLW 769
+ H + V P G+ +G D A +W
Sbjct: 438 RRCVYTIPPHQNLVTGVKFEPIHGNFLLTGAYDNTAKIW 476
Score = 54.0 bits (124), Expect = 6e-07
Identities = 42/173 (24%), Positives = 76/173 (43%), Gaps = 8/173 (4%)
Frame = +2
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAF------S 454
G IS S + + W +LW + H +V ++ F S
Sbjct: 228 GDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVS 287
Query: 455 VDNRQI--VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR 628
+D + + S + D ++KLW+ L + +GH+ V+ V + P+ + +C +DR
Sbjct: 288 LDPKDVNLASCAADGSVKLWS-LDSDEPVADIEGHTVRVARVMWHPS-GRFLGTTC-YDR 344
Query: 629 TVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGK 787
+ ++W L + ++ GHS + + DGSL +GG D +WDL G+
Sbjct: 345 SWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGR 397
>AF083383-1|AAC64084.1| 310|Homo sapiens 38kDa splicing factor
protein.
Length = 310
Score = 97.1 bits (231), Expect = 6e-20
Identities = 65/212 (30%), Positives = 104/212 (49%), Gaps = 1/212 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH G V +P + S+ D+ +++W + D +NY L GHS + ++
Sbjct: 3 LSGHEGEVYCCKFHPN-GSTLASAGFDRLILLWNVYGDCDNYAT----LKGHSGAVMELH 57
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV-SGSRDKTI 499
++DG+ S S DKT+ +WD G+ +R + HT V S + Q+V +GS D T+
Sbjct: 58 YNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTV 117
Query: 500 KLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
KLW+ K +Q ++ V V F N + I+S G D +KVW L KL
Sbjct: 118 KLWD--IRKKAAVQTFQNTYQVLAVTF--NDTSDQIISGGIDNDIKVWDLRQNKLTYTMR 173
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
GH+ + +++S +GS S D +WD+
Sbjct: 174 GHADSVTGLSLSSEGSYLLSNAMDNTVRVWDV 205
Score = 95.5 bits (227), Expect = 2e-19
Identities = 71/220 (32%), Positives = 110/220 (50%), Gaps = 9/220 (4%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDV 319
TL+GH+G V ++ N M+ S+S DKT+ VW ++ G KRL GH+ F++
Sbjct: 45 TLKGHSGAVMELHYNTD-GSMLFSASTDKTVAVW-----DSETGERVKRLKGHTSFVNSC 98
Query: 320 VLSSDG-NYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKT 496
+ G +GS D T++LWD+ + F++ T VL+V F+ + QI+SG D
Sbjct: 99 YPARRGPQLVCTGSDDGTVKLWDIRKKAAVQTFQN-TYQVLAVTFNDTSDQIISGGIDND 157
Query: 497 IKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT------NC 658
IK+W+ L + K T GH+D V+ + S + ++S D TV+VW + C
Sbjct: 158 IKVWD-LRQNKLTYTMRGHADSVTGLSLSSEGS--YLLSNAMDNTVRVWDVRPFAPKERC 214
Query: 659 KLKINHLGHSGYLNTVTVS--PDGSLCASGGKDMXAMLWD 772
H+ N + S PDGS A+G D +WD
Sbjct: 215 VKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWD 254
Score = 58.8 bits (136), Expect = 2e-08
Identities = 40/185 (21%), Positives = 80/185 (43%), Gaps = 5/185 (2%)
Frame = +2
Query: 116 SETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
SET + L+GH +V + P ++ + S D T+ +W + + + +
Sbjct: 79 SETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKA------AVQTFQ 132
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
+++ + V + + +SG D +++WDL K T H V ++ S + ++
Sbjct: 133 NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLL 192
Query: 476 SGSRDKTIKLWNT-----LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKV 640
S + D T+++W+ C Q + H+ + +R S + I + DR V V
Sbjct: 193 SNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYV 252
Query: 641 WHLTN 655
W T+
Sbjct: 253 WDTTS 257
Score = 54.0 bits (124), Expect = 6e-07
Identities = 42/170 (24%), Positives = 74/170 (43%), Gaps = 3/170 (1%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAG-KTTRRFEDHTKDVLSVAFSVDN 463
L GH + +G+ S +D+ + LW++ + H+ V+ + ++ D
Sbjct: 3 LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDG 62
Query: 464 RQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWV-SCVRFSPNHANPIIVSCGWDR-TVK 637
+ S S DKT+ +W++ + + GH+ +V SC P P +V G D TVK
Sbjct: 63 SMLFSASTDKTVAVWDSETGERVK-RLKGHTSFVNSCY---PARRGPQLVCTGSDDGTVK 118
Query: 638 VWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGK 787
+W + K + ++ + VT + SGG D +WDL K
Sbjct: 119 LWDIRK-KAAVQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNK 167
Score = 49.2 bits (112), Expect = 2e-05
Identities = 25/83 (30%), Positives = 41/83 (49%), Gaps = 1/83 (1%)
Frame = +2
Query: 548 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT-NCKLKINHLGHSGYLNTVTVSPDG 724
GH V C +F PN + + S G+DR + +W++ +C GHSG + + + DG
Sbjct: 5 GHEGEVYCCKFHPNGST--LASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDG 62
Query: 725 SLCASGGKDMXAMLWDLNDGKHL 793
S+ S D +WD G+ +
Sbjct: 63 SMLFSASTDKTVAVWDSETGERV 85
Score = 34.3 bits (75), Expect = 0.51
Identities = 25/95 (26%), Positives = 46/95 (48%), Gaps = 3/95 (3%)
Frame = +2
Query: 128 KLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKL---TRDENNYGIPQKRLYGH 298
KL T+RGH VT ++ + + +LS++ D T+ VW + E I Q ++
Sbjct: 167 KLTYTMRGHADSVTGLSLSSE-GSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNF 225
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKT 403
+ S DG+ +GS D+ + +WD + ++
Sbjct: 226 EKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRS 260
>L13387-1|AAA02882.1| 288|Homo sapiens Miller-Dieker lissencephaly
protein protein.
Length = 288
Score = 96.7 bits (230), Expect = 9e-20
Identities = 57/176 (32%), Positives = 87/176 (49%), Gaps = 1/176 (0%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLW 382
++S+S D T+ VW + G ++ L GH+ + D+ G S S D T++LW
Sbjct: 1 MVSASEDATIKVW-----DYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLW 55
Query: 383 DLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQD-DGHSD 559
D + R H +V SVA + IVS SRDKTIK+W + Y ++ GH +
Sbjct: 56 DFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWE--VQTGYCVKTFTGHRE 113
Query: 560 WVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 727
WV VR PN +I SC D+TV+VW + + K H + ++ +P+ S
Sbjct: 114 WVRMVR--PNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESS 167
Score = 81.4 bits (192), Expect = 3e-15
Identities = 61/232 (26%), Positives = 107/232 (46%), Gaps = 21/232 (9%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDV 319
T+ GH+ V+ +A P D I+S+SRDKT+ +W++ + Y + K GH ++ V
Sbjct: 65 TMHGHDHNVSSVAIMPN-GDHIVSASRDKTIKMWEV---QTGYCV--KTFTGHREWVRMV 118
Query: 320 VLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQ---------- 469
+ DG S S D+T+R+W +A + +H V ++++ ++
Sbjct: 119 RPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSE 178
Query: 470 ----------IVSGSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSC 616
++SGSRDKTIK+W+ + C T GH +WV V F + I+SC
Sbjct: 179 TKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTXV--GHDNWVRGVLF--HSGGKFILSC 234
Query: 617 GWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
D+T++VW N + H ++ ++ +G D +W+
Sbjct: 235 ADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 286
Score = 79.4 bits (187), Expect = 1e-14
Identities = 47/142 (33%), Positives = 68/142 (47%), Gaps = 1/142 (0%)
Frame = +2
Query: 347 LSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLA-E 523
+S S D T+++WD G R + HT V ++F + + S S D TIKLW+ E
Sbjct: 2 VSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFE 61
Query: 524 CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNT 703
C T+ GH VS V PN + IVS D+T+K+W + GH ++
Sbjct: 62 CIRTMH--GHDHNVSSVAIMPNGDH--IVSASRDKTIKMWEVQTGYCVKTFTGHREWVRM 117
Query: 704 VTVSPDGSLCASGGKDMXAMLW 769
V + DG+L AS D +W
Sbjct: 118 VRPNQDGTLIASCSNDQTVRVW 139
Score = 59.3 bits (137), Expect = 2e-08
Identities = 30/106 (28%), Positives = 55/106 (51%), Gaps = 1/106 (0%)
Frame = +2
Query: 470 IVSGSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWH 646
+VS S D TIK+W+ + + T++ GH+D V + F +H+ ++ SC D T+K+W
Sbjct: 1 MVSASEDATIKVWDYETGDFERTLK--GHTDSVQDISF--DHSGKLLASCSADMTIKLWD 56
Query: 647 LTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDG 784
+ GH +++V + P+G S +D +W++ G
Sbjct: 57 FQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTG 102
>AF052432-1|AAC09328.1| 655|Homo sapiens katanin p80 subunit
protein.
Length = 655
Score = 96.7 bits (230), Expect = 9e-20
Identities = 57/164 (34%), Positives = 83/164 (50%), Gaps = 1/164 (0%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNR 466
L GH+ + V L++ ++GS ++R+WDL A K R ++ S+ F
Sbjct: 59 LTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGLKANICSLDFHPYGE 118
Query: 467 QIVSGSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVW 643
+ SGS+D IKLW+ + C + + GHS V C+RFSP+ + S D TVK+W
Sbjct: 119 FVASGSQDTNIKLWDIRRKGCVFRYR--GHSQAVRCLRFSPD--GKWLASAADDHTVKLW 174
Query: 644 HLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
LT K+ GH+G +N V P+ L ASG D WDL
Sbjct: 175 DLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDGTIRFWDL 218
Score = 81.0 bits (191), Expect = 5e-15
Identities = 56/204 (27%), Positives = 94/204 (46%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDV 319
+L GH V + N ++I++ S+ ++ VW L + + L G I +
Sbjct: 58 SLTGHTSPVESVRLNTP-EELIVAGSQSGSIRVWDLEAAKI-----LRTLMGLKANICSL 111
Query: 320 VLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTI 499
G + SGS D ++LWD+ R+ H++ V + FS D + + S + D T+
Sbjct: 112 DFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTV 171
Query: 500 KLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
KLW+ A K + GH+ V+ V F PN ++ S D T++ W L ++
Sbjct: 172 KLWDLTAG-KMMSEFPGHTGPVNVVEFHPNEY--LLASGSSDGTIRFWDLEKFQVVSRIE 228
Query: 680 GHSGYLNTVTVSPDGSLCASGGKD 751
G G + +V +PDG SG +D
Sbjct: 229 GEPGPVRSVLFNPDGCCLYSGCQD 252
Score = 73.3 bits (172), Expect = 9e-13
Identities = 48/157 (30%), Positives = 75/157 (47%)
Frame = +2
Query: 119 ETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGH 298
E K+ TL G + + +P Y + + S S+D + +W + R + R GH
Sbjct: 93 EAAKILRTLMGLKANICSLDFHP-YGEFVASGSQDTNIKLWDIRRKGCVF-----RYRGH 146
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVS 478
S + + S DG + S + D T++LWDL AGK F HT V V F + + S
Sbjct: 147 SQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLAS 206
Query: 479 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPN 589
GS D TI+ W+ L + + + +G V V F+P+
Sbjct: 207 GSSDGTIRFWD-LEKFQVVSRIEGEPGPVRSVLFNPD 242
Score = 66.9 bits (156), Expect = 8e-11
Identities = 45/170 (26%), Positives = 70/170 (41%), Gaps = 1/170 (0%)
Frame = +2
Query: 281 KRLYGHSHFISDVVLS-SDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSV 457
+ + H+ +S +VL + G +G D + LW + HT V SV +
Sbjct: 14 QEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNT 73
Query: 458 DNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVK 637
IV+GS+ +I++W+ L K G + + F P + S D +K
Sbjct: 74 PEELIVAGSQSGSIRVWD-LEAAKILRTLMGLKANICSLDFHPY--GEFVASGSQDTNIK 130
Query: 638 VWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGK 787
+W + + GHS + + SPDG AS D LWDL GK
Sbjct: 131 LWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGK 180
>AK127882-1|BAC87175.1| 369|Homo sapiens protein ( Homo sapiens
cDNA FLJ45988 fis, clone PUAEN2006639, weakly similar
to Vegetatible incompatibility protein HET-E-1. ).
Length = 369
Score = 96.3 bits (229), Expect = 1e-19
Identities = 66/227 (29%), Positives = 112/227 (49%), Gaps = 3/227 (1%)
Frame = +2
Query: 116 SETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
+ T L L+ H +T +A N K ++ S D+T +W ++ G L G
Sbjct: 79 NHTFYLFKVLKAHILPLTNVALN-KSGSCFITGSYDRTCKLW-----DSASGEELNTLEG 132
Query: 296 HSHFISDVVLSSD-GNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI 472
H + + + ++ G+ +GS+DKT +LW + GK F HT +++ ++F+ + +
Sbjct: 133 HRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLV 192
Query: 473 VSGSRDKTIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 649
+GS D T KLW+ E YT++ GHS + S N + I++ +D TV VW
Sbjct: 193 ATGSMDTTAKLWDIQNGEEVYTLR--GHS--AEIISLSFNTSGDRIITGSFDHTVVVWDA 248
Query: 650 TNCKLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGK 787
+ K+N L GH +++ + + D SL +G D LWD +GK
Sbjct: 249 DTGR-KVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGK 294
Score = 95.1 bits (226), Expect = 3e-19
Identities = 53/187 (28%), Positives = 100/187 (53%), Gaps = 2/187 (1%)
Frame = +2
Query: 242 KLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFED 421
KL ++ N+ K L H +++V L+ G+ ++GS+D+T +LWD A+G+ E
Sbjct: 73 KLGQNSNHTFYLFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDSASGEELNTLEG 132
Query: 422 HTKDVLSVAFSVD-NRQIVSGSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHA 595
H V ++AF+ +I +GS DKT KLW+ +C +T + GH+ + C+ F+P
Sbjct: 133 HRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFR--GHTAEIVCLSFNPQ-- 188
Query: 596 NPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
+ ++ + D T K+W + N + GHS + +++ + G +G D ++WD
Sbjct: 189 STLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDA 248
Query: 776 NDGKHLH 796
+ G+ ++
Sbjct: 249 DTGRKVN 255
Score = 85.4 bits (202), Expect = 2e-16
Identities = 58/204 (28%), Positives = 89/204 (43%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDV 319
TL GH V IA N Y D I + S DKT +W + G GH+ I +
Sbjct: 129 TLEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVET-----GKCYHTFRGHTAEIVCL 183
Query: 320 VLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTI 499
+ +GS D T +LWD+ G+ H+ +++S++F+ +I++GS D T+
Sbjct: 184 SFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTV 243
Query: 500 KLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
+W+ K I GH +S F N +I++ D+T K+W TN K
Sbjct: 244 VVWDADTGRKVNILI-GHCAEISSASF--NWDCSLILTGSMDKTCKLWDATNGKCVATLT 300
Query: 680 GHSGYLNTVTVSPDGSLCASGGKD 751
GH + G L A+ D
Sbjct: 301 GHDDEILDSCFDYTGKLIATASAD 324
Score = 77.4 bits (182), Expect = 6e-14
Identities = 49/158 (31%), Positives = 80/158 (50%), Gaps = 3/158 (1%)
Frame = +2
Query: 119 ETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGH 298
ET K T RGH + ++ NP+ ++ + S D T +W + E Y L GH
Sbjct: 165 ETGKCYHTFRGHTAEIVCLSFNPQ-STLVATGSMDTTAKLWDIQNGEEVY-----TLRGH 218
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVS 478
S I + ++ G+ ++GS+D T+ +WD G+ H ++ S +F+ D I++
Sbjct: 219 SAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILT 278
Query: 479 GSRDKTIKLWN-TLAECKYTIQDDGHSDWV--SCVRFS 583
GS DKT KLW+ T +C T+ GH D + SC ++
Sbjct: 279 GSMDKTCKLWDATNGKCVATL--TGHDDEILDSCFDYT 314
Score = 63.3 bits (147), Expect = 1e-09
Identities = 38/122 (31%), Positives = 57/122 (46%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDV 319
TLRGH+ + ++ N D I++ S D T++VW + + G L GH IS
Sbjct: 214 TLRGHSAEIISLSFNTS-GDRIITGSFDHTVVVW-----DADTGRKVNILIGHCAEISSA 267
Query: 320 VLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTI 499
+ D + L+GS DKT +LWD GK H ++L F + I + S D +
Sbjct: 268 SFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADDGV 327
Query: 500 KL 505
L
Sbjct: 328 SL 329
>AK075289-1|BAC11525.1| 407|Homo sapiens protein ( Homo sapiens
cDNA FLJ90808 fis, clone Y79AA1000777, weakly similar to
VEGETATIBLE INCOMPATIBILITY PROTEIN HET-E-1. ).
Length = 407
Score = 95.5 bits (227), Expect = 2e-19
Identities = 66/217 (30%), Positives = 102/217 (47%), Gaps = 1/217 (0%)
Frame = +2
Query: 149 GHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLS 328
GH VT + +P ++ S SRDKT+ +W N H+ + V
Sbjct: 59 GHKDAVTCVNFSPS-GHLLASGSRDKTVRIWV-----PNVKGESTVFRAHTATVRSVHFC 112
Query: 329 SDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLW 508
SDG ++ S DKT+++W K H V FS D R IVS S DKT+KLW
Sbjct: 113 SDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLW 172
Query: 509 NTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGH 685
+ + EC ++ + H +V+ V F P+ I + G D TVKVW + +L ++ H
Sbjct: 173 DKSSRECVHSYCE--HGGFVTYVDFHPS--GTCIAAAGMDNTVKVWDVRTYRLLQHYQLH 228
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
S +N ++ P G+ + D + DL +G+ L+
Sbjct: 229 SAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLY 265
Score = 80.6 bits (190), Expect = 6e-15
Identities = 50/173 (28%), Positives = 75/173 (43%)
Frame = +2
Query: 278 QKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSV 457
++ GH ++ V S + SGS D L +W + RF H V V FS
Sbjct: 12 ERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSP 71
Query: 458 DNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVK 637
+ SGSRDKT+++W + + T+ H+ V V F + + V+ D+TVK
Sbjct: 72 SGHLLASGSRDKTVRIWVPNVKGESTV-FRAHTATVRSVHFCSDGQS--FVTASDDKTVK 128
Query: 638 VWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
VW K + H ++ SPDG L S D LWD + + +H
Sbjct: 129 VWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVH 181
Score = 80.2 bits (189), Expect = 8e-15
Identities = 54/191 (28%), Positives = 88/191 (46%)
Frame = +2
Query: 206 LSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWD 385
+++S DKT+ VW R + + + Q H +++ S DG +S S DKT++LWD
Sbjct: 119 VTASDDKTVKVWATHRQKFLFSLSQ-----HINWVRCAKFSPDGRLIVSASDDKTVKLWD 173
Query: 386 LAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWV 565
++ + + +H V V F I + D T+K+W+ + + HS V
Sbjct: 174 KSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWD-VRTYRLLQHYQLHSAAV 232
Query: 566 SCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGG 745
+ + F P + +++ D T+K+ L +L GH G TV S G ASGG
Sbjct: 233 NGLSFHP--SGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGG 290
Query: 746 KDMXAMLWDLN 778
D M+W N
Sbjct: 291 SDEQVMVWKSN 301
Score = 54.8 bits (126), Expect = 3e-07
Identities = 34/121 (28%), Positives = 54/121 (44%)
Frame = +2
Query: 152 HNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSS 331
H G+VT + +P I ++ D T+ VW D Y + Q HS ++ +
Sbjct: 186 HGGFVTYVDFHPS-GTCIAAAGMDNTVKVW----DVRTYRLLQHYQL-HSAAVNGLSFHP 239
Query: 332 DGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN 511
GNY ++ S D TL++ DL G+ H +VAFS SG D+ + +W
Sbjct: 240 SGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWK 299
Query: 512 T 514
+
Sbjct: 300 S 300
>BC119693-1|AAI19694.1| 441|Homo sapiens WDR51A protein protein.
Length = 441
Score = 95.1 bits (226), Expect = 3e-19
Identities = 66/217 (30%), Positives = 102/217 (47%), Gaps = 1/217 (0%)
Frame = +2
Query: 149 GHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLS 328
GH VT + +P ++ S SRDKT+ +W N H+ + V
Sbjct: 93 GHKDAVTCVNFSPS-GHLLASGSRDKTVRIWV-----PNVKGESTVFRAHTATVRSVHFC 146
Query: 329 SDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLW 508
SDG ++ S DKT+++W K H V FS D R IVS S DKT+KLW
Sbjct: 147 SDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLW 206
Query: 509 NTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGH 685
+ + EC ++ + H +V+ V F P+ I + G D TVKVW + +L ++ H
Sbjct: 207 DKSSRECVHSYCE--HGGFVTYVDFHPS--GTCIAAAGMDNTVKVWDVRTHRLLQHYQLH 262
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
S +N ++ P G+ + D + DL +G+ L+
Sbjct: 263 SAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLY 299
Score = 80.6 bits (190), Expect = 6e-15
Identities = 50/173 (28%), Positives = 75/173 (43%)
Frame = +2
Query: 278 QKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSV 457
++ GH ++ V S + SGS D L +W + RF H V V FS
Sbjct: 46 ERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSP 105
Query: 458 DNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVK 637
+ SGSRDKT+++W + + T+ H+ V V F + + V+ D+TVK
Sbjct: 106 SGHLLASGSRDKTVRIWVPNVKGESTV-FRAHTATVRSVHFCSDGQS--FVTASDDKTVK 162
Query: 638 VWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
VW K + H ++ SPDG L S D LWD + + +H
Sbjct: 163 VWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVH 215
Score = 80.6 bits (190), Expect = 6e-15
Identities = 54/191 (28%), Positives = 87/191 (45%)
Frame = +2
Query: 206 LSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWD 385
+++S DKT+ VW R + + + Q H +++ S DG +S S DKT++LWD
Sbjct: 153 VTASDDKTVKVWATHRQKFLFSLSQ-----HINWVRCAKFSPDGRLIVSASDDKTVKLWD 207
Query: 386 LAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWV 565
++ + + +H V V F I + D T+K+W+ + HS V
Sbjct: 208 KSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTH-RLLQHYQLHSAAV 266
Query: 566 SCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGG 745
+ + F P + +++ D T+K+ L +L GH G TV S G ASGG
Sbjct: 267 NGLSFHP--SGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGG 324
Query: 746 KDMXAMLWDLN 778
D M+W N
Sbjct: 325 SDEQVMVWKSN 335
Score = 52.8 bits (121), Expect = 1e-06
Identities = 33/121 (27%), Positives = 54/121 (44%)
Frame = +2
Query: 152 HNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSS 331
H G+VT + +P I ++ D T+ VW D + + Q HS ++ +
Sbjct: 220 HGGFVTYVDFHPS-GTCIAAAGMDNTVKVW----DVRTHRLLQHYQL-HSAAVNGLSFHP 273
Query: 332 DGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN 511
GNY ++ S D TL++ DL G+ H +VAFS SG D+ + +W
Sbjct: 274 SGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWK 333
Query: 512 T 514
+
Sbjct: 334 S 334
>BC119692-1|AAI19693.1| 407|Homo sapiens WD repeat domain 51A
protein.
Length = 407
Score = 95.1 bits (226), Expect = 3e-19
Identities = 66/217 (30%), Positives = 102/217 (47%), Gaps = 1/217 (0%)
Frame = +2
Query: 149 GHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLS 328
GH VT + +P ++ S SRDKT+ +W N H+ + V
Sbjct: 59 GHKDAVTCVNFSPS-GHLLASGSRDKTVRIWV-----PNVKGESTVFRAHTATVRSVHFC 112
Query: 329 SDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLW 508
SDG ++ S DKT+++W K H V FS D R IVS S DKT+KLW
Sbjct: 113 SDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLW 172
Query: 509 NTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGH 685
+ + EC ++ + H +V+ V F P+ I + G D TVKVW + +L ++ H
Sbjct: 173 DKSSRECVHSYCE--HGGFVTYVDFHPS--GTCIAAAGMDNTVKVWDVRTHRLLQHYQLH 228
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
S +N ++ P G+ + D + DL +G+ L+
Sbjct: 229 SAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLY 265
Score = 80.6 bits (190), Expect = 6e-15
Identities = 50/173 (28%), Positives = 75/173 (43%)
Frame = +2
Query: 278 QKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSV 457
++ GH ++ V S + SGS D L +W + RF H V V FS
Sbjct: 12 ERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSP 71
Query: 458 DNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVK 637
+ SGSRDKT+++W + + T+ H+ V V F + + V+ D+TVK
Sbjct: 72 SGHLLASGSRDKTVRIWVPNVKGESTV-FRAHTATVRSVHFCSDGQS--FVTASDDKTVK 128
Query: 638 VWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
VW K + H ++ SPDG L S D LWD + + +H
Sbjct: 129 VWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVH 181
Score = 80.6 bits (190), Expect = 6e-15
Identities = 54/191 (28%), Positives = 87/191 (45%)
Frame = +2
Query: 206 LSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWD 385
+++S DKT+ VW R + + + Q H +++ S DG +S S DKT++LWD
Sbjct: 119 VTASDDKTVKVWATHRQKFLFSLSQ-----HINWVRCAKFSPDGRLIVSASDDKTVKLWD 173
Query: 386 LAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWV 565
++ + + +H V V F I + D T+K+W+ + HS V
Sbjct: 174 KSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTH-RLLQHYQLHSAAV 232
Query: 566 SCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGG 745
+ + F P + +++ D T+K+ L +L GH G TV S G ASGG
Sbjct: 233 NGLSFHP--SGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGG 290
Query: 746 KDMXAMLWDLN 778
D M+W N
Sbjct: 291 SDEQVMVWKSN 301
Score = 52.8 bits (121), Expect = 1e-06
Identities = 33/121 (27%), Positives = 54/121 (44%)
Frame = +2
Query: 152 HNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSS 331
H G+VT + +P I ++ D T+ VW D + + Q HS ++ +
Sbjct: 186 HGGFVTYVDFHPS-GTCIAAAGMDNTVKVW----DVRTHRLLQHYQL-HSAAVNGLSFHP 239
Query: 332 DGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN 511
GNY ++ S D TL++ DL G+ H +VAFS SG D+ + +W
Sbjct: 240 SGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWK 299
Query: 512 T 514
+
Sbjct: 300 S 300
>BC110877-1|AAI10878.1| 359|Homo sapiens WDR51A protein protein.
Length = 359
Score = 95.1 bits (226), Expect = 3e-19
Identities = 66/217 (30%), Positives = 102/217 (47%), Gaps = 1/217 (0%)
Frame = +2
Query: 149 GHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLS 328
GH VT + +P ++ S SRDKT+ +W N H+ + V
Sbjct: 59 GHKDAVTCVNFSPS-GHLLASGSRDKTVRIWV-----PNVKGESTVFRAHTATVRSVHFC 112
Query: 329 SDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLW 508
SDG ++ S DKT+++W K H V FS D R IVS S DKT+KLW
Sbjct: 113 SDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLW 172
Query: 509 NTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGH 685
+ + EC ++ + H +V+ V F P+ I + G D TVKVW + +L ++ H
Sbjct: 173 DKSSRECVHSYCE--HGGFVTYVDFHPS--GTCIAAAGMDNTVKVWDVRTHRLLQHYQLH 228
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
S +N ++ P G+ + D + DL +G+ L+
Sbjct: 229 SAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLY 265
Score = 80.6 bits (190), Expect = 6e-15
Identities = 50/173 (28%), Positives = 75/173 (43%)
Frame = +2
Query: 278 QKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSV 457
++ GH ++ V S + SGS D L +W + RF H V V FS
Sbjct: 12 ERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSP 71
Query: 458 DNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVK 637
+ SGSRDKT+++W + + T+ H+ V V F + + V+ D+TVK
Sbjct: 72 SGHLLASGSRDKTVRIWVPNVKGESTV-FRAHTATVRSVHFCSDGQS--FVTASDDKTVK 128
Query: 638 VWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
VW K + H ++ SPDG L S D LWD + + +H
Sbjct: 129 VWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVH 181
Score = 80.6 bits (190), Expect = 6e-15
Identities = 54/191 (28%), Positives = 87/191 (45%)
Frame = +2
Query: 206 LSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWD 385
+++S DKT+ VW R + + + Q H +++ S DG +S S DKT++LWD
Sbjct: 119 VTASDDKTVKVWATHRQKFLFSLSQ-----HINWVRCAKFSPDGRLIVSASDDKTVKLWD 173
Query: 386 LAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWV 565
++ + + +H V V F I + D T+K+W+ + HS V
Sbjct: 174 KSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTH-RLLQHYQLHSAAV 232
Query: 566 SCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGG 745
+ + F P + +++ D T+K+ L +L GH G TV S G ASGG
Sbjct: 233 NGLSFHP--SGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGG 290
Query: 746 KDMXAMLWDLN 778
D M+W N
Sbjct: 291 SDEQVMVWKSN 301
Score = 52.8 bits (121), Expect = 1e-06
Identities = 33/121 (27%), Positives = 54/121 (44%)
Frame = +2
Query: 152 HNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSS 331
H G+VT + +P I ++ D T+ VW D + + Q HS ++ +
Sbjct: 186 HGGFVTYVDFHPS-GTCIAAAGMDNTVKVW----DVRTHRLLQHYQL-HSAAVNGLSFHP 239
Query: 332 DGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN 511
GNY ++ S D TL++ DL G+ H +VAFS SG D+ + +W
Sbjct: 240 SGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWK 299
Query: 512 T 514
+
Sbjct: 300 S 300
>BC007417-1|AAH07417.2| 396|Homo sapiens WDR51A protein protein.
Length = 396
Score = 95.1 bits (226), Expect = 3e-19
Identities = 66/217 (30%), Positives = 102/217 (47%), Gaps = 1/217 (0%)
Frame = +2
Query: 149 GHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLS 328
GH VT + +P ++ S SRDKT+ +W N H+ + V
Sbjct: 48 GHKDAVTCVNFSPS-GHLLASGSRDKTVRIWV-----PNVKGESTVFRAHTATVRSVHFC 101
Query: 329 SDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLW 508
SDG ++ S DKT+++W K H V FS D R IVS S DKT+KLW
Sbjct: 102 SDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLW 161
Query: 509 NTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGH 685
+ + EC ++ + H +V+ V F P+ I + G D TVKVW + +L ++ H
Sbjct: 162 DKSSRECVHSYCE--HGGFVTYVDFHPS--GTCIAAAGMDNTVKVWDVRTHRLLQHYQLH 217
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
S +N ++ P G+ + D + DL +G+ L+
Sbjct: 218 SAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLY 254
Score = 80.6 bits (190), Expect = 6e-15
Identities = 50/173 (28%), Positives = 75/173 (43%)
Frame = +2
Query: 278 QKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSV 457
++ GH ++ V S + SGS D L +W + RF H V V FS
Sbjct: 1 ERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSP 60
Query: 458 DNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVK 637
+ SGSRDKT+++W + + T+ H+ V V F + + V+ D+TVK
Sbjct: 61 SGHLLASGSRDKTVRIWVPNVKGESTV-FRAHTATVRSVHFCSDGQS--FVTASDDKTVK 117
Query: 638 VWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
VW K + H ++ SPDG L S D LWD + + +H
Sbjct: 118 VWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVH 170
Score = 80.6 bits (190), Expect = 6e-15
Identities = 54/191 (28%), Positives = 87/191 (45%)
Frame = +2
Query: 206 LSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWD 385
+++S DKT+ VW R + + + Q H +++ S DG +S S DKT++LWD
Sbjct: 108 VTASDDKTVKVWATHRQKFLFSLSQ-----HINWVRCAKFSPDGRLIVSASDDKTVKLWD 162
Query: 386 LAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWV 565
++ + + +H V V F I + D T+K+W+ + HS V
Sbjct: 163 KSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTH-RLLQHYQLHSAAV 221
Query: 566 SCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGG 745
+ + F P + +++ D T+K+ L +L GH G TV S G ASGG
Sbjct: 222 NGLSFHP--SGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGG 279
Query: 746 KDMXAMLWDLN 778
D M+W N
Sbjct: 280 SDEQVMVWKSN 290
Score = 52.8 bits (121), Expect = 1e-06
Identities = 33/121 (27%), Positives = 54/121 (44%)
Frame = +2
Query: 152 HNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSS 331
H G+VT + +P I ++ D T+ VW D + + Q HS ++ +
Sbjct: 175 HGGFVTYVDFHPS-GTCIAAAGMDNTVKVW----DVRTHRLLQHYQL-HSAAVNGLSFHP 228
Query: 332 DGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN 511
GNY ++ S D TL++ DL G+ H +VAFS SG D+ + +W
Sbjct: 229 SGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWK 288
Query: 512 T 514
+
Sbjct: 289 S 289
>U82756-1|AAC02261.1| 520|Homo sapiens WD splicing factor Hprp4p
protein.
Length = 520
Score = 94.7 bits (225), Expect = 3e-19
Identities = 61/210 (29%), Positives = 98/210 (46%), Gaps = 1/210 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
+ GH V ++ +P + ++ D++ +W L E + Q+ GHS + D+
Sbjct: 317 IEGHTVRVARVMWHPS-GRFLGTTCYDRSWRLWDLEAQEEI--LHQE---GHSMGVYDIA 370
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
DG+ A +G D R+WDL G+ E H K++ + FS + I +GS D T K
Sbjct: 371 FHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCK 430
Query: 503 LWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
+W+ C YTI H + V+ V+F P H N +++ +D T K+W
Sbjct: 431 VWDLRQRRCVYTI--PAHQNLVTGVKFEPIHGN-FLLTGAYDNTAKIWTHPGWSPLKTLA 487
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
GH G + + +S DG L A+ D LW
Sbjct: 488 GHEGKVMGLDISSDGQLIATCSYDRTFKLW 517
Score = 73.7 bits (173), Expect = 7e-13
Identities = 60/218 (27%), Positives = 97/218 (44%), Gaps = 8/218 (3%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYP------DMILSS-SRDKTLIVWKLTRDENNYGIPQKRLYGH 298
TLRGHN Q+ + PK D+ L+S + D ++ +W L DE P + GH
Sbjct: 266 TLRGHNTKKEQLHSIPKSTVSLDPKDVNLASCAADGSVKLWSLDSDE-----PVADIEGH 320
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVS 478
+ ++ V+ G + + +D++ RLWDL A + E H+ V +AF D +
Sbjct: 321 TVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGT 380
Query: 479 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 658
G D ++W+ L + + +GH + + FSPN + I + D T KVW L
Sbjct: 381 GGLDAFGRVWD-LRTGRCIMFLEGHLKEIYGINFSPNGYH--IATGSGDNTCKVWDLRQR 437
Query: 659 KLKINHLGHSGYLNTVTVSP-DGSLCASGGKDMXAMLW 769
+ H + V P G+ +G D A +W
Sbjct: 438 RCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIW 475
Score = 53.2 bits (122), Expect = 1e-06
Identities = 41/173 (23%), Positives = 77/173 (44%), Gaps = 8/173 (4%)
Frame = +2
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLA--------AGKTTRRFEDHTKDVLSVA 448
G IS S + + W +LW + G T++ + H+ +V+
Sbjct: 227 GDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTKKEQLHSIPKSTVS 286
Query: 449 FSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR 628
+ + S + D ++KLW+ L + +GH+ V+ V + P+ + +C +DR
Sbjct: 287 LDPKDVNLASCAADGSVKLWS-LDSDEPVADIEGHTVRVARVMWHPS-GRFLGTTC-YDR 343
Query: 629 TVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGK 787
+ ++W L + ++ GHS + + DGSL +GG D +WDL G+
Sbjct: 344 SWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGR 396
Score = 51.2 bits (117), Expect = 4e-06
Identities = 35/138 (25%), Positives = 64/138 (46%)
Frame = +2
Query: 362 DKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQ 541
D +++LW L + + E HT V V + R + + D++ +LW+ A+ + +
Sbjct: 300 DGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQ-EEILH 358
Query: 542 DDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPD 721
+GHS V + F + + + + G D +VW L + + GH + + SP+
Sbjct: 359 QEGHSMGVYDIAFHQDGS--LAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPN 416
Query: 722 GSLCASGGKDMXAMLWDL 775
G A+G D +WDL
Sbjct: 417 GYHIATGSGDNTCKVWDL 434
>CR457105-1|CAG33386.1| 521|Homo sapiens PRPF4 protein.
Length = 521
Score = 94.7 bits (225), Expect = 3e-19
Identities = 61/210 (29%), Positives = 98/210 (46%), Gaps = 1/210 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
+ GH V ++ +P + ++ D++ +W L E + Q+ GHS + D+
Sbjct: 318 IEGHTVRVARVMWHPS-GRFLGTTCYDRSWRLWDLEAQEEI--LHQE---GHSMGVYDIA 371
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
DG+ A +G D R+WDL G+ E H K++ + FS + I +GS D T K
Sbjct: 372 FHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCK 431
Query: 503 LWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
+W+ C YTI H + V+ V+F P H N +++ +D T K+W
Sbjct: 432 VWDLRQRRCVYTI--PAHQNLVTGVKFEPIHGN-FLLTGAYDNTAKIWTHPGWSPLKTLA 488
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
GH G + + +S DG L A+ D LW
Sbjct: 489 GHEGKVMGLDISSDGQLIATCSYDRTFKLW 518
Score = 74.9 bits (176), Expect = 3e-13
Identities = 61/218 (27%), Positives = 97/218 (44%), Gaps = 8/218 (3%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYP------DMILSS-SRDKTLIVWKLTRDENNYGIPQKRLYGH 298
TLRGHN V I +PK D+ L+S + D ++ +W L DE P + GH
Sbjct: 267 TLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDE-----PVADIEGH 321
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVS 478
+ ++ V+ G + + +D++ RLWDL A + E H+ V +AF D +
Sbjct: 322 TVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGT 381
Query: 479 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 658
G D ++W+ L + + +GH + + FSPN + I + D T KVW L
Sbjct: 382 GGLDAFGRVWD-LRTGRCIMFLEGHLKEIYGINFSPNGYH--IATGSGDNTCKVWDLRQR 438
Query: 659 KLKINHLGHSGYLNTVTVSP-DGSLCASGGKDMXAMLW 769
+ H + V P G+ +G D A +W
Sbjct: 439 RCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIW 476
Score = 54.0 bits (124), Expect = 6e-07
Identities = 42/173 (24%), Positives = 76/173 (43%), Gaps = 8/173 (4%)
Frame = +2
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAF------S 454
G IS S + + W +LW + H +V ++ F S
Sbjct: 228 GDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVS 287
Query: 455 VDNRQI--VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR 628
+D + + S + D ++KLW+ L + +GH+ V+ V + P+ + +C +DR
Sbjct: 288 LDPKDVNLASCAADGSVKLWS-LDSDEPVADIEGHTVRVARVMWHPS-GRFLGTTC-YDR 344
Query: 629 TVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGK 787
+ ++W L + ++ GHS + + DGSL +GG D +WDL G+
Sbjct: 345 SWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGR 397
Score = 51.2 bits (117), Expect = 4e-06
Identities = 35/138 (25%), Positives = 64/138 (46%)
Frame = +2
Query: 362 DKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQ 541
D +++LW L + + E HT V V + R + + D++ +LW+ A+ + +
Sbjct: 301 DGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQ-EEILH 359
Query: 542 DDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPD 721
+GHS V + F + + + + G D +VW L + + GH + + SP+
Sbjct: 360 QEGHSMGVYDIAFHQDGS--LAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPN 417
Query: 722 GSLCASGGKDMXAMLWDL 775
G A+G D +WDL
Sbjct: 418 GYHIATGSGDNTCKVWDL 435
>BC007424-1|AAH07424.1| 521|Homo sapiens PRP4 pre-mRNA processing
factor 4 homolog (yeast) protein.
Length = 521
Score = 94.7 bits (225), Expect = 3e-19
Identities = 61/210 (29%), Positives = 98/210 (46%), Gaps = 1/210 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
+ GH V ++ +P + ++ D++ +W L E + Q+ GHS + D+
Sbjct: 318 IEGHTVRVARVMWHPS-GRFLGTTCYDRSWRLWDLEAQEEI--LHQE---GHSMGVYDIA 371
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
DG+ A +G D R+WDL G+ E H K++ + FS + I +GS D T K
Sbjct: 372 FHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCK 431
Query: 503 LWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
+W+ C YTI H + V+ V+F P H N +++ +D T K+W
Sbjct: 432 VWDLRQRRCVYTI--PAHQNLVTGVKFEPIHGN-FLLTGAYDNTAKIWTHPGWSPLKTLA 488
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
GH G + + +S DG L A+ D LW
Sbjct: 489 GHEGKVMGLDISSDGQLIATCSYDRTFKLW 518
Score = 74.9 bits (176), Expect = 3e-13
Identities = 61/218 (27%), Positives = 97/218 (44%), Gaps = 8/218 (3%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYP------DMILSS-SRDKTLIVWKLTRDENNYGIPQKRLYGH 298
TLRGHN V I +PK D+ L+S + D ++ +W L DE P + GH
Sbjct: 267 TLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDE-----PVADIEGH 321
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVS 478
+ ++ V+ G + + +D++ RLWDL A + E H+ V +AF D +
Sbjct: 322 TVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGT 381
Query: 479 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 658
G D ++W+ L + + +GH + + FSPN + I + D T KVW L
Sbjct: 382 GGLDAFGRVWD-LRTGRCIMFLEGHLKEIYGINFSPNGYH--IATGSGDNTCKVWDLRQR 438
Query: 659 KLKINHLGHSGYLNTVTVSP-DGSLCASGGKDMXAMLW 769
+ H + V P G+ +G D A +W
Sbjct: 439 RCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIW 476
Score = 54.0 bits (124), Expect = 6e-07
Identities = 42/173 (24%), Positives = 76/173 (43%), Gaps = 8/173 (4%)
Frame = +2
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAF------S 454
G IS S + + W +LW + H +V ++ F S
Sbjct: 228 GDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVS 287
Query: 455 VDNRQI--VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR 628
+D + + S + D ++KLW+ L + +GH+ V+ V + P+ + +C +DR
Sbjct: 288 LDPKDVNLASCAADGSVKLWS-LDSDEPVADIEGHTVRVARVMWHPS-GRFLGTTC-YDR 344
Query: 629 TVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGK 787
+ ++W L + ++ GHS + + DGSL +GG D +WDL G+
Sbjct: 345 SWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGR 397
Score = 51.2 bits (117), Expect = 4e-06
Identities = 35/138 (25%), Positives = 64/138 (46%)
Frame = +2
Query: 362 DKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQ 541
D +++LW L + + E HT V V + R + + D++ +LW+ A+ + +
Sbjct: 301 DGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQ-EEILH 359
Query: 542 DDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPD 721
+GHS V + F + + + + G D +VW L + + GH + + SP+
Sbjct: 360 QEGHSMGVYDIAFHQDGS--LAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPN 417
Query: 722 GSLCASGGKDMXAMLWDL 775
G A+G D +WDL
Sbjct: 418 GYHIATGSGDNTCKVWDL 435
>BC001588-1|AAH01588.1| 522|Homo sapiens PRP4 pre-mRNA processing
factor 4 homolog (yeast) protein.
Length = 522
Score = 94.7 bits (225), Expect = 3e-19
Identities = 61/210 (29%), Positives = 98/210 (46%), Gaps = 1/210 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
+ GH V ++ +P + ++ D++ +W L E + Q+ GHS + D+
Sbjct: 319 IEGHTVRVARVMWHPS-GRFLGTTCYDRSWRLWDLEAQEEI--LHQE---GHSMGVYDIA 372
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
DG+ A +G D R+WDL G+ E H K++ + FS + I +GS D T K
Sbjct: 373 FHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCK 432
Query: 503 LWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
+W+ C YTI H + V+ V+F P H N +++ +D T K+W
Sbjct: 433 VWDLRQRRCVYTI--PAHQNLVTGVKFEPIHGN-FLLTGAYDNTAKIWTHPGWSPLKTLA 489
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
GH G + + +S DG L A+ D LW
Sbjct: 490 GHEGKVMGLDISSDGQLIATCSYDRTFKLW 519
Score = 74.9 bits (176), Expect = 3e-13
Identities = 61/218 (27%), Positives = 97/218 (44%), Gaps = 8/218 (3%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYP------DMILSS-SRDKTLIVWKLTRDENNYGIPQKRLYGH 298
TLRGHN V I +PK D+ L+S + D ++ +W L DE P + GH
Sbjct: 268 TLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDE-----PVADIEGH 322
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVS 478
+ ++ V+ G + + +D++ RLWDL A + E H+ V +AF D +
Sbjct: 323 TVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGT 382
Query: 479 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 658
G D ++W+ L + + +GH + + FSPN + I + D T KVW L
Sbjct: 383 GGLDAFGRVWD-LRTGRCIMFLEGHLKEIYGINFSPNGYH--IATGSGDNTCKVWDLRQR 439
Query: 659 KLKINHLGHSGYLNTVTVSP-DGSLCASGGKDMXAMLW 769
+ H + V P G+ +G D A +W
Sbjct: 440 RCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIW 477
Score = 54.0 bits (124), Expect = 6e-07
Identities = 42/173 (24%), Positives = 76/173 (43%), Gaps = 8/173 (4%)
Frame = +2
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAF------S 454
G IS S + + W +LW + H +V ++ F S
Sbjct: 229 GDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVS 288
Query: 455 VDNRQI--VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR 628
+D + + S + D ++KLW+ L + +GH+ V+ V + P+ + +C +DR
Sbjct: 289 LDPKDVNLASCAADGSVKLWS-LDSDEPVADIEGHTVRVARVMWHPS-GRFLGTTC-YDR 345
Query: 629 TVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGK 787
+ ++W L + ++ GHS + + DGSL +GG D +WDL G+
Sbjct: 346 SWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGR 398
Score = 51.2 bits (117), Expect = 4e-06
Identities = 35/138 (25%), Positives = 64/138 (46%)
Frame = +2
Query: 362 DKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQ 541
D +++LW L + + E HT V V + R + + D++ +LW+ A+ + +
Sbjct: 302 DGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQ-EEILH 360
Query: 542 DDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPD 721
+GHS V + F + + + + G D +VW L + + GH + + SP+
Sbjct: 361 QEGHSMGVYDIAFHQDGS--LAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPN 418
Query: 722 GSLCASGGKDMXAMLWDL 775
G A+G D +WDL
Sbjct: 419 GYHIATGSGDNTCKVWDL 436
>AY572489-1|AAS78572.1| 521|Homo sapiens 60 kDa U4/U6
snRNP-specific spliceosomal protein protein.
Length = 521
Score = 94.7 bits (225), Expect = 3e-19
Identities = 61/210 (29%), Positives = 98/210 (46%), Gaps = 1/210 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
+ GH V ++ +P + ++ D++ +W L E + Q+ GHS + D+
Sbjct: 318 IEGHTVRVARVMWHPS-GRFLGTTCYDRSWRLWDLEAQEEI--LHQE---GHSMGVYDIA 371
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
DG+ A +G D R+WDL G+ E H K++ + FS + I +GS D T K
Sbjct: 372 FHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCK 431
Query: 503 LWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
+W+ C YTI H + V+ V+F P H N +++ +D T K+W
Sbjct: 432 VWDLRQRRCVYTI--PAHQNLVTGVKFEPIHGN-FLLTGAYDNTAKIWTHPGWSPLKTLA 488
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
GH G + + +S DG L A+ D LW
Sbjct: 489 GHEGKVMGLDISSDGQLIATCSYDRTFKLW 518
Score = 74.9 bits (176), Expect = 3e-13
Identities = 61/218 (27%), Positives = 97/218 (44%), Gaps = 8/218 (3%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYP------DMILSS-SRDKTLIVWKLTRDENNYGIPQKRLYGH 298
TLRGHN V I +PK D+ L+S + D ++ +W L DE P + GH
Sbjct: 267 TLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDE-----PVADIEGH 321
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVS 478
+ ++ V+ G + + +D++ RLWDL A + E H+ V +AF D +
Sbjct: 322 TVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGT 381
Query: 479 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 658
G D ++W+ L + + +GH + + FSPN + I + D T KVW L
Sbjct: 382 GGLDAFGRVWD-LRTGRCIMFLEGHLKEIYGINFSPNGYH--IATGSGDNTCKVWDLRQR 438
Query: 659 KLKINHLGHSGYLNTVTVSP-DGSLCASGGKDMXAMLW 769
+ H + V P G+ +G D A +W
Sbjct: 439 RCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIW 476
Score = 54.0 bits (124), Expect = 6e-07
Identities = 42/173 (24%), Positives = 76/173 (43%), Gaps = 8/173 (4%)
Frame = +2
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAF------S 454
G IS S + + W +LW + H +V ++ F S
Sbjct: 228 GDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVS 287
Query: 455 VDNRQI--VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR 628
+D + + S + D ++KLW+ L + +GH+ V+ V + P+ + +C +DR
Sbjct: 288 LDPKDVNLASCAADGSVKLWS-LDSDEPVADIEGHTVRVARVMWHPS-GRFLGTTC-YDR 344
Query: 629 TVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGK 787
+ ++W L + ++ GHS + + DGSL +GG D +WDL G+
Sbjct: 345 SWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGR 397
Score = 51.2 bits (117), Expect = 4e-06
Identities = 35/138 (25%), Positives = 64/138 (46%)
Frame = +2
Query: 362 DKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQ 541
D +++LW L + + E HT V V + R + + D++ +LW+ A+ + +
Sbjct: 301 DGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQ-EEILH 359
Query: 542 DDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPD 721
+GHS V + F + + + + G D +VW L + + GH + + SP+
Sbjct: 360 QEGHSMGVYDIAFHQDGS--LAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPN 417
Query: 722 GSLCASGGKDMXAMLWDL 775
G A+G D +WDL
Sbjct: 418 GYHIATGSGDNTCKVWDL 435
>AL449305-8|CAI10969.1| 521|Homo sapiens PRP4 pre-mRNA processing
factor 4 homolog (yeast) protein.
Length = 521
Score = 94.7 bits (225), Expect = 3e-19
Identities = 61/210 (29%), Positives = 98/210 (46%), Gaps = 1/210 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
+ GH V ++ +P + ++ D++ +W L E + Q+ GHS + D+
Sbjct: 318 IEGHTVRVARVMWHPS-GRFLGTTCYDRSWRLWDLEAQEEI--LHQE---GHSMGVYDIA 371
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
DG+ A +G D R+WDL G+ E H K++ + FS + I +GS D T K
Sbjct: 372 FHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCK 431
Query: 503 LWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
+W+ C YTI H + V+ V+F P H N +++ +D T K+W
Sbjct: 432 VWDLRQRRCVYTI--PAHQNLVTGVKFEPIHGN-FLLTGAYDNTAKIWTHPGWSPLKTLA 488
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
GH G + + +S DG L A+ D LW
Sbjct: 489 GHEGKVMGLDISSDGQLIATCSYDRTFKLW 518
Score = 74.9 bits (176), Expect = 3e-13
Identities = 61/218 (27%), Positives = 97/218 (44%), Gaps = 8/218 (3%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYP------DMILSS-SRDKTLIVWKLTRDENNYGIPQKRLYGH 298
TLRGHN V I +PK D+ L+S + D ++ +W L DE P + GH
Sbjct: 267 TLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDE-----PVADIEGH 321
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVS 478
+ ++ V+ G + + +D++ RLWDL A + E H+ V +AF D +
Sbjct: 322 TVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGT 381
Query: 479 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 658
G D ++W+ L + + +GH + + FSPN + I + D T KVW L
Sbjct: 382 GGLDAFGRVWD-LRTGRCIMFLEGHLKEIYGINFSPNGYH--IATGSGDNTCKVWDLRQR 438
Query: 659 KLKINHLGHSGYLNTVTVSP-DGSLCASGGKDMXAMLW 769
+ H + V P G+ +G D A +W
Sbjct: 439 RCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIW 476
Score = 54.0 bits (124), Expect = 6e-07
Identities = 42/173 (24%), Positives = 76/173 (43%), Gaps = 8/173 (4%)
Frame = +2
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAF------S 454
G IS S + + W +LW + H +V ++ F S
Sbjct: 228 GDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVS 287
Query: 455 VDNRQI--VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR 628
+D + + S + D ++KLW+ L + +GH+ V+ V + P+ + +C +DR
Sbjct: 288 LDPKDVNLASCAADGSVKLWS-LDSDEPVADIEGHTVRVARVMWHPS-GRFLGTTC-YDR 344
Query: 629 TVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGK 787
+ ++W L + ++ GHS + + DGSL +GG D +WDL G+
Sbjct: 345 SWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGR 397
Score = 51.2 bits (117), Expect = 4e-06
Identities = 35/138 (25%), Positives = 64/138 (46%)
Frame = +2
Query: 362 DKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQ 541
D +++LW L + + E HT V V + R + + D++ +LW+ A+ + +
Sbjct: 301 DGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQ-EEILH 359
Query: 542 DDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPD 721
+GHS V + F + + + + G D +VW L + + GH + + SP+
Sbjct: 360 QEGHSMGVYDIAFHQDGS--LAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPN 417
Query: 722 GSLCASGGKDMXAMLWDL 775
G A+G D +WDL
Sbjct: 418 GYHIATGSGDNTCKVWDL 435
>AL449305-7|CAI10968.1| 522|Homo sapiens PRP4 pre-mRNA processing
factor 4 homolog (yeast) protein.
Length = 522
Score = 94.7 bits (225), Expect = 3e-19
Identities = 61/210 (29%), Positives = 98/210 (46%), Gaps = 1/210 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
+ GH V ++ +P + ++ D++ +W L E + Q+ GHS + D+
Sbjct: 319 IEGHTVRVARVMWHPS-GRFLGTTCYDRSWRLWDLEAQEEI--LHQE---GHSMGVYDIA 372
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
DG+ A +G D R+WDL G+ E H K++ + FS + I +GS D T K
Sbjct: 373 FHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCK 432
Query: 503 LWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
+W+ C YTI H + V+ V+F P H N +++ +D T K+W
Sbjct: 433 VWDLRQRRCVYTI--PAHQNLVTGVKFEPIHGN-FLLTGAYDNTAKIWTHPGWSPLKTLA 489
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
GH G + + +S DG L A+ D LW
Sbjct: 490 GHEGKVMGLDISSDGQLIATCSYDRTFKLW 519
Score = 74.9 bits (176), Expect = 3e-13
Identities = 61/218 (27%), Positives = 97/218 (44%), Gaps = 8/218 (3%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYP------DMILSS-SRDKTLIVWKLTRDENNYGIPQKRLYGH 298
TLRGHN V I +PK D+ L+S + D ++ +W L DE P + GH
Sbjct: 268 TLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDE-----PVADIEGH 322
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVS 478
+ ++ V+ G + + +D++ RLWDL A + E H+ V +AF D +
Sbjct: 323 TVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGT 382
Query: 479 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 658
G D ++W+ L + + +GH + + FSPN + I + D T KVW L
Sbjct: 383 GGLDAFGRVWD-LRTGRCIMFLEGHLKEIYGINFSPNGYH--IATGSGDNTCKVWDLRQR 439
Query: 659 KLKINHLGHSGYLNTVTVSP-DGSLCASGGKDMXAMLW 769
+ H + V P G+ +G D A +W
Sbjct: 440 RCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIW 477
Score = 54.0 bits (124), Expect = 6e-07
Identities = 42/173 (24%), Positives = 76/173 (43%), Gaps = 8/173 (4%)
Frame = +2
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAF------S 454
G IS S + + W +LW + H +V ++ F S
Sbjct: 229 GDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVS 288
Query: 455 VDNRQI--VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR 628
+D + + S + D ++KLW+ L + +GH+ V+ V + P+ + +C +DR
Sbjct: 289 LDPKDVNLASCAADGSVKLWS-LDSDEPVADIEGHTVRVARVMWHPS-GRFLGTTC-YDR 345
Query: 629 TVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGK 787
+ ++W L + ++ GHS + + DGSL +GG D +WDL G+
Sbjct: 346 SWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGR 398
Score = 51.2 bits (117), Expect = 4e-06
Identities = 35/138 (25%), Positives = 64/138 (46%)
Frame = +2
Query: 362 DKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQ 541
D +++LW L + + E HT V V + R + + D++ +LW+ A+ + +
Sbjct: 302 DGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQ-EEILH 360
Query: 542 DDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPD 721
+GHS V + F + + + + G D +VW L + + GH + + SP+
Sbjct: 361 QEGHSMGVYDIAFHQDGS--LAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPN 418
Query: 722 GSLCASGGKDMXAMLWDL 775
G A+G D +WDL
Sbjct: 419 GYHIATGSGDNTCKVWDL 436
>AL121990-7|CAI22015.1| 589|Homo sapiens TAF5-like RNA polymerase
II, p300/CBP-associated factor (PCAF)-associated facto
protein.
Length = 589
Score = 94.7 bits (225), Expect = 3e-19
Identities = 61/194 (31%), Positives = 92/194 (47%), Gaps = 1/194 (0%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLY-GHSHFISDVVLSSDGNYALSGSWDKTLRL 379
+LS S D ++ W L N LY GH++ + D+ +S Y SGS D+T RL
Sbjct: 357 LLSCSEDMSIRYWDLGSFTNTV------LYQGHAYPVWDLDISPYSLYFASGSHDRTARL 410
Query: 380 WDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSD 559
W R + H DV V F ++ + +GS DKT++LW+ + GH
Sbjct: 411 WSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFT-GHRG 469
Query: 560 WVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCAS 739
V + FSPN + S G D+ +K+W L + L GH+ + ++T SPD L AS
Sbjct: 470 PVLSLAFSPN--GKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSGLIAS 527
Query: 740 GGKDMXAMLWDLND 781
D +WD+ +
Sbjct: 528 ASMDNSVRVWDIRN 541
Score = 89.0 bits (211), Expect = 2e-17
Identities = 54/170 (31%), Positives = 84/170 (49%)
Frame = +2
Query: 146 RGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVL 325
+GH V + +P Y S S D+T +W R P + GH + V
Sbjct: 381 QGHAYPVWDLDISP-YSLYFASGSHDRTARLWSFDRT-----YPLRIYAGHLADVDCVKF 434
Query: 326 SSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKL 505
+ NY +GS DKT+RLW G + R F H VLS+AFS + + + S D+ +KL
Sbjct: 435 HPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKL 494
Query: 506 WNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 655
W+ + Y + GH+D ++ + FSP+ + +I S D +V+VW + N
Sbjct: 495 WDLASGTLYK-ELRGHTDNITSLTFSPD--SGLIASASMDNSVRVWDIRN 541
Score = 86.6 bits (205), Expect = 9e-17
Identities = 54/177 (30%), Positives = 82/177 (46%)
Frame = +2
Query: 254 DENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKD 433
+++N G K L GH + +D + LS S D ++R WDL + T ++ H
Sbjct: 327 EDDNAGTEMKILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYP 386
Query: 434 VLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVS 613
V + S + SGS D+T +LW+ I GH V CV+F PN + + +
Sbjct: 387 VWDLDISPYSLYFASGSHDRTARLWSFDRTYPLRIY-AGHLADVDCVKFHPN--SNYLAT 443
Query: 614 CGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDG 784
D+TV++W GH G + ++ SP+G AS G+D LWDL G
Sbjct: 444 GSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASG 500
>AJ009770-1|CAA08816.1| 260|Homo sapiens putative transcription
factor protein.
Length = 260
Score = 94.7 bits (225), Expect = 3e-19
Identities = 61/194 (31%), Positives = 92/194 (47%), Gaps = 1/194 (0%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLY-GHSHFISDVVLSSDGNYALSGSWDKTLRL 379
+LS S D ++ W L N LY GH++ + D+ +S Y SGS D+T RL
Sbjct: 28 LLSCSEDMSIRYWDLGSFTNTV------LYQGHAYPVWDLDISPYSLYFASGSHDRTARL 81
Query: 380 WDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSD 559
W R + H DV V F ++ + +GS DKT++LW+ + GH
Sbjct: 82 WSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFT-GHRG 140
Query: 560 WVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCAS 739
V + FSPN + S G D+ +K+W L + L GH+ + ++T SPD L AS
Sbjct: 141 PVLSLAFSPN--GKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSGLIAS 198
Query: 740 GGKDMXAMLWDLND 781
D +WD+ +
Sbjct: 199 ASMDNSVRVWDIRN 212
Score = 89.0 bits (211), Expect = 2e-17
Identities = 54/170 (31%), Positives = 84/170 (49%)
Frame = +2
Query: 146 RGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVL 325
+GH V + +P Y S S D+T +W R P + GH + V
Sbjct: 52 QGHAYPVWDLDISP-YSLYFASGSHDRTARLWSFDRT-----YPLRIYAGHLADVDCVKF 105
Query: 326 SSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKL 505
+ NY +GS DKT+RLW G + R F H VLS+AFS + + + S D+ +KL
Sbjct: 106 HPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKL 165
Query: 506 WNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 655
W+ + Y + GH+D ++ + FSP+ + +I S D +V+VW + N
Sbjct: 166 WDLASGTLYK-ELRGHTDNITSLTFSPD--SGLIASASMDNSVRVWDIRN 212
Score = 84.6 bits (200), Expect = 4e-16
Identities = 54/174 (31%), Positives = 79/174 (45%)
Frame = +2
Query: 263 NYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLS 442
N G K L GH + +D + LS S D ++R WDL + T ++ H V
Sbjct: 1 NAGTEMKILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWD 60
Query: 443 VAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGW 622
+ S + SGS D+T +LW+ I GH V CV+F PN + + +
Sbjct: 61 LDISPYSLYFASGSHDRTARLWSFDRTYPLRIY-AGHLADVDCVKFHPN--SNYLATGST 117
Query: 623 DRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDG 784
D+TV++W GH G + ++ SP+G AS G+D LWDL G
Sbjct: 118 DKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASG 171
>AF069736-1|AAC39906.1| 589|Homo sapiens PCAF associated factor 65
beta protein.
Length = 589
Score = 94.7 bits (225), Expect = 3e-19
Identities = 61/194 (31%), Positives = 92/194 (47%), Gaps = 1/194 (0%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLY-GHSHFISDVVLSSDGNYALSGSWDKTLRL 379
+LS S D ++ W L N LY GH++ + D+ +S Y SGS D+T RL
Sbjct: 357 LLSCSEDMSIRYWDLGSFTNTV------LYQGHAYPVWDLDISPYSLYFASGSHDRTARL 410
Query: 380 WDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSD 559
W R + H DV V F ++ + +GS DKT++LW+ + GH
Sbjct: 411 WSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFT-GHRG 469
Query: 560 WVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCAS 739
V + FSPN + S G D+ +K+W L + L GH+ + ++T SPD L AS
Sbjct: 470 PVLSLAFSPN--GKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSGLIAS 527
Query: 740 GGKDMXAMLWDLND 781
D +WD+ +
Sbjct: 528 ASMDNSVRVWDIRN 541
Score = 89.0 bits (211), Expect = 2e-17
Identities = 54/170 (31%), Positives = 84/170 (49%)
Frame = +2
Query: 146 RGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVL 325
+GH V + +P Y S S D+T +W R P + GH + V
Sbjct: 381 QGHAYPVWDLDISP-YSLYFASGSHDRTARLWSFDRT-----YPLRIYAGHLADVDCVKF 434
Query: 326 SSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKL 505
+ NY +GS DKT+RLW G + R F H VLS+AFS + + + S D+ +KL
Sbjct: 435 HPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKL 494
Query: 506 WNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 655
W+ + Y + GH+D ++ + FSP+ + +I S D +V+VW + N
Sbjct: 495 WDLASGTLYK-ELRGHTDNITSLTFSPD--SGLIASASMDNSVRVWDIRN 541
Score = 86.6 bits (205), Expect = 9e-17
Identities = 54/177 (30%), Positives = 82/177 (46%)
Frame = +2
Query: 254 DENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKD 433
+++N G K L GH + +D + LS S D ++R WDL + T ++ H
Sbjct: 327 EDDNAGTEMKILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYP 386
Query: 434 VLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVS 613
V + S + SGS D+T +LW+ I GH V CV+F PN + + +
Sbjct: 387 VWDLDISPYSLYFASGSHDRTARLWSFDRTYPLRIY-AGHLADVDCVKFHPN--SNYLAT 443
Query: 614 CGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDG 784
D+TV++W GH G + ++ SP+G AS G+D LWDL G
Sbjct: 444 GSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASG 500
>AF016369-1|AAC51925.1| 522|Homo sapiens U4/U6 small nuclear
ribonucleoprotein hPrp4 protein.
Length = 522
Score = 94.7 bits (225), Expect = 3e-19
Identities = 61/210 (29%), Positives = 98/210 (46%), Gaps = 1/210 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
+ GH V ++ +P + ++ D++ +W L E + Q+ GHS + D+
Sbjct: 319 IEGHTVRVARVMWHPS-GRFLGTTCYDRSWRLWDLEAQEEI--LHQE---GHSMGVYDIA 372
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
DG+ A +G D R+WDL G+ E H K++ + FS + I +GS D T K
Sbjct: 373 FHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCK 432
Query: 503 LWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
+W+ C YTI H + V+ V+F P H N +++ +D T K+W
Sbjct: 433 VWDLRQRRCVYTI--PAHQNLVTGVKFEPIHGN-FLLTGAYDNTAKIWTHPGWSPLKTLA 489
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
GH G + + +S DG L A+ D LW
Sbjct: 490 GHEGKVMGLDISSDGQLIATCSYDRTFKLW 519
Score = 74.9 bits (176), Expect = 3e-13
Identities = 61/218 (27%), Positives = 97/218 (44%), Gaps = 8/218 (3%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYP------DMILSS-SRDKTLIVWKLTRDENNYGIPQKRLYGH 298
TLRGHN V I +PK D+ L+S + D ++ +W L DE P + GH
Sbjct: 268 TLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDE-----PVADIEGH 322
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVS 478
+ ++ V+ G + + +D++ RLWDL A + E H+ V +AF D +
Sbjct: 323 TVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGT 382
Query: 479 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 658
G D ++W+ L + + +GH + + FSPN + I + D T KVW L
Sbjct: 383 GGLDAFGRVWD-LRTGRCIMFLEGHLKEIYGINFSPNGYH--IATGSGDNTCKVWDLRQR 439
Query: 659 KLKINHLGHSGYLNTVTVSP-DGSLCASGGKDMXAMLW 769
+ H + V P G+ +G D A +W
Sbjct: 440 RCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIW 477
Score = 54.0 bits (124), Expect = 6e-07
Identities = 42/173 (24%), Positives = 76/173 (43%), Gaps = 8/173 (4%)
Frame = +2
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAF------S 454
G IS S + + W +LW + H +V ++ F S
Sbjct: 229 GDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVS 288
Query: 455 VDNRQI--VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR 628
+D + + S + D ++KLW+ L + +GH+ V+ V + P+ + +C +DR
Sbjct: 289 LDPKDVNLASCAADGSVKLWS-LDSDEPVADIEGHTVRVARVMWHPS-GRFLGTTC-YDR 345
Query: 629 TVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGK 787
+ ++W L + ++ GHS + + DGSL +GG D +WDL G+
Sbjct: 346 SWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGR 398
Score = 51.2 bits (117), Expect = 4e-06
Identities = 35/138 (25%), Positives = 64/138 (46%)
Frame = +2
Query: 362 DKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQ 541
D +++LW L + + E HT V V + R + + D++ +LW+ A+ + +
Sbjct: 302 DGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQ-EEILH 360
Query: 542 DDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPD 721
+GHS V + F + + + + G D +VW L + + GH + + SP+
Sbjct: 361 QEGHSMGVYDIAFHQDGS--LAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPN 418
Query: 722 GSLCASGGKDMXAMLWDL 775
G A+G D +WDL
Sbjct: 419 GYHIATGSGDNTCKVWDL 436
>AB209797-1|BAD93034.1| 537|Homo sapiens PRPF4 protein variant
protein.
Length = 537
Score = 94.7 bits (225), Expect = 3e-19
Identities = 61/210 (29%), Positives = 98/210 (46%), Gaps = 1/210 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
+ GH V ++ +P + ++ D++ +W L E + Q+ GHS + D+
Sbjct: 334 IEGHTVRVARVMWHPS-GRFLGTTCYDRSWRLWDLEAQEEI--LHQE---GHSMGVYDIA 387
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
DG+ A +G D R+WDL G+ E H K++ + FS + I +GS D T K
Sbjct: 388 FHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCK 447
Query: 503 LWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
+W+ C YTI H + V+ V+F P H N +++ +D T K+W
Sbjct: 448 VWDLRQRRCVYTI--PAHQNLVTGVKFEPIHGN-FLLTGAYDNTAKIWTHPGWSPLKTLA 504
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
GH G + + +S DG L A+ D LW
Sbjct: 505 GHEGKVMGLDISSDGQLIATCSYDRTFKLW 534
Score = 74.9 bits (176), Expect = 3e-13
Identities = 61/218 (27%), Positives = 97/218 (44%), Gaps = 8/218 (3%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYP------DMILSS-SRDKTLIVWKLTRDENNYGIPQKRLYGH 298
TLRGHN V I +PK D+ L+S + D ++ +W L DE P + GH
Sbjct: 283 TLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDE-----PVADIEGH 337
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVS 478
+ ++ V+ G + + +D++ RLWDL A + E H+ V +AF D +
Sbjct: 338 TVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGT 397
Query: 479 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 658
G D ++W+ L + + +GH + + FSPN + I + D T KVW L
Sbjct: 398 GGLDAFGRVWD-LRTGRCIMFLEGHLKEIYGINFSPNGYH--IATGSGDNTCKVWDLRQR 454
Query: 659 KLKINHLGHSGYLNTVTVSP-DGSLCASGGKDMXAMLW 769
+ H + V P G+ +G D A +W
Sbjct: 455 RCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIW 492
Score = 54.0 bits (124), Expect = 6e-07
Identities = 42/173 (24%), Positives = 76/173 (43%), Gaps = 8/173 (4%)
Frame = +2
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAF------S 454
G IS S + + W +LW + H +V ++ F S
Sbjct: 244 GDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVS 303
Query: 455 VDNRQI--VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR 628
+D + + S + D ++KLW+ L + +GH+ V+ V + P+ + +C +DR
Sbjct: 304 LDPKDVNLASCAADGSVKLWS-LDSDEPVADIEGHTVRVARVMWHPS-GRFLGTTC-YDR 360
Query: 629 TVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGK 787
+ ++W L + ++ GHS + + DGSL +GG D +WDL G+
Sbjct: 361 SWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGR 413
Score = 51.2 bits (117), Expect = 4e-06
Identities = 35/138 (25%), Positives = 64/138 (46%)
Frame = +2
Query: 362 DKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQ 541
D +++LW L + + E HT V V + R + + D++ +LW+ A+ + +
Sbjct: 317 DGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQ-EEILH 375
Query: 542 DDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPD 721
+GHS V + F + + + + G D +VW L + + GH + + SP+
Sbjct: 376 QEGHSMGVYDIAFHQDGS--LAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPN 433
Query: 722 GSLCASGGKDMXAMLWDL 775
G A+G D +WDL
Sbjct: 434 GYHIATGSGDNTCKVWDL 451
>BC025379-1|AAH25379.1| 571|Homo sapiens SPAG16 protein protein.
Length = 571
Score = 90.2 bits (214), Expect = 7e-18
Identities = 62/220 (28%), Positives = 107/220 (48%), Gaps = 5/220 (2%)
Frame = +2
Query: 128 KLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRL----YG 295
KL+ R H V+ ++ +P + D+++S D+ +WK+ G+P+ + +G
Sbjct: 283 KLKNIFRLHELPVSCVSMHP-HKDILVSCGEDR---LWKVL------GLPKCNVLLTGFG 332
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H+ ++SD G+ + S D T++LWDL G FE H++ V S + +
Sbjct: 333 HTDWLSDCCFHPSGDKLATSSGDTTVKLWDLCKGDCILTFEGHSRAVWSCTWHSCGNFVA 392
Query: 476 SGSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
S S DKT K+W+ +E C+ T+ GH+D V+ + F P +N ++ S D+T+ +W
Sbjct: 393 SSSLDKTSKIWDVNSERCRCTLY--GHTDSVNSIEFFP-FSNTLLTSSA-DKTLSIWDAR 448
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ + GH +N P G + AS LWD
Sbjct: 449 TGICEQSLYGHMHSINDAIFDPRGHMIASCDACGVTKLWD 488
Score = 58.0 bits (134), Expect = 4e-08
Identities = 51/210 (24%), Positives = 79/210 (37%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDV 319
T GH+ V T + + SSS DKT +W + + LYGH+ ++ +
Sbjct: 371 TFEGHSRAVWS-CTWHSCGNFVASSSLDKTSKIWDVNSERCRC-----TLYGHTDSVNSI 424
Query: 320 VLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTI 499
N L+ S DKTL +WD G + H + F I S
Sbjct: 425 EFFPFSNTLLTSSADKTLSIWDARTGICEQSLYGHMHSINDAIFDPRGHMIASCDACGVT 484
Query: 500 KLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
KLW+ D G S V F + + ++ + + + L + ++ +
Sbjct: 485 KLWDFRKLLPIVSIDIGPSPGNE-VNF--DSSGRVLAQASGNGVIHLLDLKSGEIH-KLM 540
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
GH +TV S DG + SGG D W
Sbjct: 541 GHENEAHTVVFSHDGEILFSGGSDGTVRTW 570
Score = 53.2 bits (122), Expect = 1e-06
Identities = 28/74 (37%), Positives = 36/74 (48%)
Frame = +2
Query: 563 VSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASG 742
VSCV P+ I+VSCG DR KV L C + + GH+ +L+ P G A+
Sbjct: 295 VSCVSMHPH--KDILVSCGEDRLWKVLGLPKCNVLLTGFGHTDWLSDCCFHPSGDKLATS 352
Query: 743 GKDMXAMLWDLNDG 784
D LWDL G
Sbjct: 353 SGDTTVKLWDLCKG 366
Score = 51.2 bits (117), Expect = 4e-06
Identities = 43/215 (20%), Positives = 83/215 (38%), Gaps = 2/215 (0%)
Frame = +2
Query: 146 RGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG-HSHFISDVV 322
R N T++ N K + + + L V K + + K ++ H +S V
Sbjct: 240 REQNKCKTKMKGNTKDSEFPIDMQPNPNLNVSKESLSPAKFDYKLKNIFRLHELPVSCVS 299
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
+ + +S D+ ++ L HT + F ++ + S D T+K
Sbjct: 300 MHPHKDILVSCGEDRLWKVLGLPKCNVLLTGFGHTDWLSDCCFHPSGDKLATSSGDTTVK 359
Query: 503 LWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
LW+ +C T + + W SC S + + S D+T K+W + + + +
Sbjct: 360 LWDLCKGDCILTFEGHSRAVW-SCTWHSCGN---FVASSSLDKTSKIWDVNSERCRCTLY 415
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDG 784
GH+ +N++ P + + D +WD G
Sbjct: 416 GHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTG 450
>AF490390-1|AAM97147.1| 631|Homo sapiens sperm-associated WD repeat
protein protein.
Length = 631
Score = 90.2 bits (214), Expect = 7e-18
Identities = 62/220 (28%), Positives = 106/220 (48%), Gaps = 5/220 (2%)
Frame = +2
Query: 128 KLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRL----YG 295
KL+ R H V+ ++ P + D+++S D+ +WK+ G+P+ + +G
Sbjct: 343 KLKNIFRLHELPVSCVSMQP-HKDILVSCGEDR---LWKVL------GLPKCNVLLTGFG 392
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H+ ++SD G+ + S D T++LWDL G FE H++ V S + +
Sbjct: 393 HTDWLSDCCFHPSGDKLATSSGDTTVKLWDLCTGDCILTFEGHSRAVWSCTWHSCGNFVA 452
Query: 476 SGSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
S S DKT K+W+ +E C+ T+ GH+D V+ + F P +N ++ S D+T+ +W
Sbjct: 453 SSSLDKTSKIWDVNSERCRCTLY--GHTDSVNSIEFFP-FSNTLLTSSA-DKTLSIWDAR 508
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ + GH +N P G + AS LWD
Sbjct: 509 TGICEQSLYGHMHSINDAIFDPRGHMIASCDACGVTKLWD 548
Score = 58.0 bits (134), Expect = 4e-08
Identities = 51/210 (24%), Positives = 79/210 (37%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDV 319
T GH+ V T + + SSS DKT +W + + LYGH+ ++ +
Sbjct: 431 TFEGHSRAVWS-CTWHSCGNFVASSSLDKTSKIWDVNSERCRC-----TLYGHTDSVNSI 484
Query: 320 VLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTI 499
N L+ S DKTL +WD G + H + F I S
Sbjct: 485 EFFPFSNTLLTSSADKTLSIWDARTGICEQSLYGHMHSINDAIFDPRGHMIASCDACGVT 544
Query: 500 KLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
KLW+ D G S V F + + ++ + + + L + ++ +
Sbjct: 545 KLWDFRKLLPIVSIDIGPSPGNE-VNF--DSSGRVLAQASGNGVIHLLDLKSGEIH-KLM 600
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
GH +TV S DG + SGG D W
Sbjct: 601 GHENEAHTVVFSHDGEILFSGGSDGTVRTW 630
Score = 53.6 bits (123), Expect = 8e-07
Identities = 28/74 (37%), Positives = 36/74 (48%)
Frame = +2
Query: 563 VSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASG 742
VSCV P+ I+VSCG DR KV L C + + GH+ +L+ P G A+
Sbjct: 355 VSCVSMQPH--KDILVSCGEDRLWKVLGLPKCNVLLTGFGHTDWLSDCCFHPSGDKLATS 412
Query: 743 GKDMXAMLWDLNDG 784
D LWDL G
Sbjct: 413 SGDTTVKLWDLCTG 426
Score = 51.6 bits (118), Expect = 3e-06
Identities = 43/215 (20%), Positives = 83/215 (38%), Gaps = 2/215 (0%)
Frame = +2
Query: 146 RGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG-HSHFISDVV 322
R N T++ N K + + + L V K + + K ++ H +S V
Sbjct: 300 REQNKCKTKMKGNTKDSEFPIDMQPNPNLNVSKESLSPAKFDYKLKNIFRLHELPVSCVS 359
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
+ + +S D+ ++ L HT + F ++ + S D T+K
Sbjct: 360 MQPHKDILVSCGEDRLWKVLGLPKCNVLLTGFGHTDWLSDCCFHPSGDKLATSSGDTTVK 419
Query: 503 LWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
LW+ +C T + + W SC S + + S D+T K+W + + + +
Sbjct: 420 LWDLCTGDCILTFEGHSRAVW-SCTWHSCGN---FVASSSLDKTSKIWDVNSERCRCTLY 475
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDG 784
GH+ +N++ P + + D +WD G
Sbjct: 476 GHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTG 510
>AF310672-1|AAM63956.1| 631|Homo sapiens PF20 variant 1a protein.
Length = 631
Score = 90.2 bits (214), Expect = 7e-18
Identities = 62/220 (28%), Positives = 106/220 (48%), Gaps = 5/220 (2%)
Frame = +2
Query: 128 KLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRL----YG 295
KL+ R H V+ ++ P + D+++S D+ +WK+ G+P+ + +G
Sbjct: 343 KLKNIFRLHELPVSCVSMQP-HKDILVSCGEDR---LWKVL------GLPKCNVLLTGFG 392
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H+ ++SD G+ + S D T++LWDL G FE H++ V S + +
Sbjct: 393 HTDWLSDCCFHPSGDKLATSSGDTTVKLWDLCTGDCILTFEGHSRAVWSCTWHSCGNFVA 452
Query: 476 SGSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
S S DKT K+W+ +E C+ T+ GH+D V+ + F P +N ++ S D+T+ +W
Sbjct: 453 SSSLDKTSKIWDVNSERCRCTLY--GHTDSVNSIEFFP-FSNTLLTSSA-DKTLSIWDAR 508
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ + GH +N P G + AS LWD
Sbjct: 509 TGICEQSLYGHMHSINDAIFDPRGHMIASCDACGVTKLWD 548
Score = 58.0 bits (134), Expect = 4e-08
Identities = 51/210 (24%), Positives = 79/210 (37%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDV 319
T GH+ V T + + SSS DKT +W + + LYGH+ ++ +
Sbjct: 431 TFEGHSRAVWS-CTWHSCGNFVASSSLDKTSKIWDVNSERCRC-----TLYGHTDSVNSI 484
Query: 320 VLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTI 499
N L+ S DKTL +WD G + H + F I S
Sbjct: 485 EFFPFSNTLLTSSADKTLSIWDARTGICEQSLYGHMHSINDAIFDPRGHMIASCDACGVT 544
Query: 500 KLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
KLW+ D G S V F + + ++ + + + L + ++ +
Sbjct: 545 KLWDFRKLLPIVSIDIGPSPGNE-VNF--DSSGRVLAQASGNGVIHLLDLKSGEIH-KLM 600
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
GH +TV S DG + SGG D W
Sbjct: 601 GHENEAHTVVFSHDGEILFSGGSDGTVRTW 630
Score = 53.6 bits (123), Expect = 8e-07
Identities = 28/74 (37%), Positives = 36/74 (48%)
Frame = +2
Query: 563 VSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASG 742
VSCV P+ I+VSCG DR KV L C + + GH+ +L+ P G A+
Sbjct: 355 VSCVSMQPH--KDILVSCGEDRLWKVLGLPKCNVLLTGFGHTDWLSDCCFHPSGDKLATS 412
Query: 743 GKDMXAMLWDLNDG 784
D LWDL G
Sbjct: 413 SGDTTVKLWDLCTG 426
Score = 51.6 bits (118), Expect = 3e-06
Identities = 43/215 (20%), Positives = 83/215 (38%), Gaps = 2/215 (0%)
Frame = +2
Query: 146 RGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG-HSHFISDVV 322
R N T++ N K + + + L V K + + K ++ H +S V
Sbjct: 300 REQNKCKTKMKGNTKDSEFPIDMQPNPNLNVSKESLSPAKFDYKLKNIFRLHELPVSCVS 359
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
+ + +S D+ ++ L HT + F ++ + S D T+K
Sbjct: 360 MQPHKDILVSCGEDRLWKVLGLPKCNVLLTGFGHTDWLSDCCFHPSGDKLATSSGDTTVK 419
Query: 503 LWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
LW+ +C T + + W SC S + + S D+T K+W + + + +
Sbjct: 420 LWDLCTGDCILTFEGHSRAVW-SCTWHSCGN---FVASSSLDKTSKIWDVNSERCRCTLY 475
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDG 784
GH+ +N++ P + + D +WD G
Sbjct: 476 GHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTG 510
>AB053276-1|BAB69430.1| 348|Homo sapiens TUWD12 protein.
Length = 348
Score = 90.2 bits (214), Expect = 7e-18
Identities = 52/164 (31%), Positives = 78/164 (47%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNR 466
LY H+H++ S DG +S S DKT+++WD + F D V F+
Sbjct: 10 LYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGT 69
Query: 467 QIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWH 646
I S D+T+K+W+ K HS V+C+ F P + +++ D T+K+
Sbjct: 70 CIASAGSDQTVKVWDVRVN-KLLQHYQVHSGGVNCISFHP--SGNYLITASSDGTLKILD 126
Query: 647 LTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLN 778
L +L GH+G + TV+ S G L ASGG D +LW N
Sbjct: 127 LLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLWRTN 170
Score = 70.1 bits (164), Expect = 8e-12
Identities = 44/126 (34%), Positives = 65/126 (51%), Gaps = 1/126 (0%)
Frame = +2
Query: 422 HTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHAN 598
HT V FS D R IVS S DKTIK+W+T +C D + + V F+P+
Sbjct: 13 HTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDS--VGFANFVDFNPS--G 68
Query: 599 PIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLN 778
I S G D+TVKVW + KL ++ HSG +N ++ P G+ + D + DL
Sbjct: 69 TCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLL 128
Query: 779 DGKHLH 796
+G+ ++
Sbjct: 129 EGRLIY 134
Score = 60.9 bits (141), Expect = 5e-09
Identities = 46/171 (26%), Positives = 79/171 (46%), Gaps = 3/171 (1%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDE--NNYGIPQKRLYGHSHFIS 313
+L H WV +P +I+S S DKT+ +W T + NN+ G ++F+
Sbjct: 9 SLYRHTHWVRCAKFSPD-GRLIVSCSEDKTIKIWDTTNKQCVNNF----SDSVGFANFVD 63
Query: 314 DVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDK 493
+ G S D+T+++WD+ K + ++ H+ V ++F +++ S D
Sbjct: 64 ---FNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDG 120
Query: 494 TIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVW 643
T+K+ + L YT+Q GH+ V V FS + S G D V +W
Sbjct: 121 TLKILDLLEGRLIYTLQ--GHTGPVFTVSFS--KGGELFASGGADTQVLLW 167
>AB053266-1|BAB69057.1| 348|Homo sapiens TUWD12 protein.
Length = 348
Score = 90.2 bits (214), Expect = 7e-18
Identities = 52/164 (31%), Positives = 78/164 (47%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNR 466
LY H+H++ S DG +S S DKT+++WD + F D V F+
Sbjct: 10 LYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGT 69
Query: 467 QIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWH 646
I S D+T+K+W+ K HS V+C+ F P + +++ D T+K+
Sbjct: 70 CIASAGSDQTVKVWDVRVN-KLLQHYQVHSGGVNCISFHP--SGNYLITASSDGTLKILD 126
Query: 647 LTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLN 778
L +L GH+G + TV+ S G L ASGG D +LW N
Sbjct: 127 LLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLWRTN 170
Score = 70.1 bits (164), Expect = 8e-12
Identities = 44/126 (34%), Positives = 65/126 (51%), Gaps = 1/126 (0%)
Frame = +2
Query: 422 HTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHAN 598
HT V FS D R IVS S DKTIK+W+T +C D + + V F+P+
Sbjct: 13 HTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDS--VGFANFVDFNPS--G 68
Query: 599 PIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLN 778
I S G D+TVKVW + KL ++ HSG +N ++ P G+ + D + DL
Sbjct: 69 TCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLL 128
Query: 779 DGKHLH 796
+G+ ++
Sbjct: 129 EGRLIY 134
Score = 60.9 bits (141), Expect = 5e-09
Identities = 46/171 (26%), Positives = 79/171 (46%), Gaps = 3/171 (1%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDE--NNYGIPQKRLYGHSHFIS 313
+L H WV +P +I+S S DKT+ +W T + NN+ G ++F+
Sbjct: 9 SLYRHTHWVRCAKFSPD-GRLIVSCSEDKTIKIWDTTNKQCVNNF----SDSVGFANFVD 63
Query: 314 DVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDK 493
+ G S D+T+++WD+ K + ++ H+ V ++F +++ S D
Sbjct: 64 ---FNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDG 120
Query: 494 TIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVW 643
T+K+ + L YT+Q GH+ V V FS + S G D V +W
Sbjct: 121 TLKILDLLEGRLIYTLQ--GHTGPVFTVSFS--KGGELFASGGADTQVLLW 167
>BC106004-1|AAI06005.1| 514|Homo sapiens pleiotropic regulator 1
(PRL1 homolog, Arabidopsis) protein.
Length = 514
Score = 89.8 bits (213), Expect = 1e-17
Identities = 62/223 (27%), Positives = 98/223 (43%), Gaps = 1/223 (0%)
Frame = +2
Query: 128 KLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHF 307
KL + GH GWV IA P ++ S D+T+ +W L G + L GH
Sbjct: 195 KLYRVISGHLGWVRCIAVEPGN-QWFVTGSADRTIKIWDLAS-----GKLKLSLTGHIST 248
Query: 308 ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSR 487
+ V++S+ Y S DK ++ WDL K R + H V + +V+ SR
Sbjct: 249 VRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSR 308
Query: 488 DKTIKLWNTLAECK-YTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKL 664
D T ++W+ + +T+ GH++ V+ VR A P I++ D T+++W L K
Sbjct: 309 DSTARIWDVRTKASVHTL--SGHTNAVATVRCQA--AEPQIITGSHDTTIRLWDLVAGKT 364
Query: 665 KINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
++ H + V + P ASG D W DG +
Sbjct: 365 RVTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQ-WKFPDGSFI 406
Score = 83.4 bits (197), Expect = 8e-16
Identities = 61/219 (27%), Positives = 93/219 (42%)
Frame = +2
Query: 128 KLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHF 307
KL+ +L GH V + + + P + S DK + W L Y + +GH
Sbjct: 237 KLKLSLTGHISTVRGVIVSTRSP-YLFSCGEDKQVKCWDL-----EYNKVIRHYHGHLSA 290
Query: 308 ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSR 487
+ + L + ++ S D T R+WD+ + HT V +V QI++GS
Sbjct: 291 VYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSH 350
Query: 488 DKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLK 667
D TI+LW+ +A K + H V V P H + G +K W +
Sbjct: 351 DTTIRLWDLVAG-KTRVTLTNHKKSVRAVVLHPRHYT---FASGSPDNIKQWKFPDGSFI 406
Query: 668 INHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDG 784
N GH+ +NT+TV+ DG L SG + LWD G
Sbjct: 407 QNLSGHNAIINTLTVNSDGVL-VSGADNGTMHLWDWRTG 444
Score = 62.5 bits (145), Expect = 2e-09
Identities = 40/133 (30%), Positives = 62/133 (46%)
Frame = +2
Query: 398 KTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVR 577
K R H V +A N+ V+GS D+TIK+W+ LA K + GH V V
Sbjct: 195 KLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWD-LASGKLKLSLTGHISTVRGVI 253
Query: 578 FSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMX 757
S +P + SCG D+ VK W L K+ ++ GH + + + P + + +D
Sbjct: 254 VSTR--SPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDST 311
Query: 758 AMLWDLNDGKHLH 796
A +WD+ +H
Sbjct: 312 ARIWDVRTKASVH 324
Score = 60.1 bits (139), Expect = 9e-09
Identities = 44/175 (25%), Positives = 85/175 (48%), Gaps = 2/175 (1%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYP--DMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGH 298
L+ +R ++G ++ + +P D++++ SRD T +W + + + L GH
Sbjct: 275 LEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVH-----TLSGH 329
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVS 478
++ ++ V + ++GS D T+RLWDL AGKT +H K V +V + S
Sbjct: 330 TNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPRHYTFAS 389
Query: 479 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVW 643
GS D IK W + + GH+ ++ + +++ ++VS + T+ +W
Sbjct: 390 GSPD-NIKQWK-FPDGSFIQNLSGHNAIINTLTV---NSDGVLVSGADNGTMHLW 439
>BC020786-1|AAH20786.1| 505|Homo sapiens PLRG1 protein protein.
Length = 505
Score = 89.8 bits (213), Expect = 1e-17
Identities = 62/223 (27%), Positives = 98/223 (43%), Gaps = 1/223 (0%)
Frame = +2
Query: 128 KLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHF 307
KL + GH GWV IA P ++ S D+T+ +W L G + L GH
Sbjct: 186 KLYRVISGHLGWVRCIAVEPGN-QWFVTGSADRTIKIWDLAS-----GKLKLSLTGHIST 239
Query: 308 ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSR 487
+ V++S+ Y S DK ++ WDL K R + H V + +V+ SR
Sbjct: 240 VRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSR 299
Query: 488 DKTIKLWNTLAECK-YTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKL 664
D T ++W+ + +T+ GH++ V+ VR A P I++ D T+++W L K
Sbjct: 300 DSTARIWDVRTKASVHTL--SGHTNAVATVRCQA--AEPQIITGSHDTTIRLWDLVAGKT 355
Query: 665 KINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
++ H + V + P ASG D W DG +
Sbjct: 356 RVTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQ-WKFPDGSFI 397
Score = 83.4 bits (197), Expect = 8e-16
Identities = 61/219 (27%), Positives = 93/219 (42%)
Frame = +2
Query: 128 KLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHF 307
KL+ +L GH V + + + P + S DK + W L Y + +GH
Sbjct: 228 KLKLSLTGHISTVRGVIVSTRSP-YLFSCGEDKQVKCWDL-----EYNKVIRHYHGHLSA 281
Query: 308 ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSR 487
+ + L + ++ S D T R+WD+ + HT V +V QI++GS
Sbjct: 282 VYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSH 341
Query: 488 DKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLK 667
D TI+LW+ +A K + H V V P H + G +K W +
Sbjct: 342 DTTIRLWDLVAG-KTRVTLTNHKKSVRAVVLHPRHYT---FASGSPDNIKQWKFPDGSFI 397
Query: 668 INHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDG 784
N GH+ +NT+TV+ DG L SG + LWD G
Sbjct: 398 QNLSGHNAIINTLTVNSDGVL-VSGADNGTMHLWDWRTG 435
Score = 62.5 bits (145), Expect = 2e-09
Identities = 40/133 (30%), Positives = 62/133 (46%)
Frame = +2
Query: 398 KTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVR 577
K R H V +A N+ V+GS D+TIK+W+ LA K + GH V V
Sbjct: 186 KLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWD-LASGKLKLSLTGHISTVRGVI 244
Query: 578 FSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMX 757
S +P + SCG D+ VK W L K+ ++ GH + + + P + + +D
Sbjct: 245 VSTR--SPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDST 302
Query: 758 AMLWDLNDGKHLH 796
A +WD+ +H
Sbjct: 303 ARIWDVRTKASVH 315
Score = 60.1 bits (139), Expect = 9e-09
Identities = 44/175 (25%), Positives = 85/175 (48%), Gaps = 2/175 (1%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYP--DMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGH 298
L+ +R ++G ++ + +P D++++ SRD T +W + + + L GH
Sbjct: 266 LEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVH-----TLSGH 320
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVS 478
++ ++ V + ++GS D T+RLWDL AGKT +H K V +V + S
Sbjct: 321 TNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPRHYTFAS 380
Query: 479 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVW 643
GS D IK W + + GH+ ++ + +++ ++VS + T+ +W
Sbjct: 381 GSPD-NIKQWK-FPDGSFIQNLSGHNAIINTLTV---NSDGVLVSGADNGTMHLW 430
>AF044333-1|AAD09407.1| 514|Homo sapiens pleiotropic regulator 1
protein.
Length = 514
Score = 89.8 bits (213), Expect = 1e-17
Identities = 62/223 (27%), Positives = 98/223 (43%), Gaps = 1/223 (0%)
Frame = +2
Query: 128 KLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHF 307
KL + GH GWV IA P ++ S D+T+ +W L G + L GH
Sbjct: 195 KLYRVISGHLGWVRCIAVEPGN-QWFVTGSADRTIKIWDLAS-----GKLKLSLTGHIST 248
Query: 308 ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSR 487
+ V++S+ Y S DK ++ WDL K R + H V + +V+ SR
Sbjct: 249 VRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSR 308
Query: 488 DKTIKLWNTLAECK-YTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKL 664
D T ++W+ + +T+ GH++ V+ VR A P I++ D T+++W L K
Sbjct: 309 DSTARIWDVRTKASVHTL--SGHTNAVATVRCQA--AEPQIITGSHDTTIRLWDLVAGKT 364
Query: 665 KINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
++ H + V + P ASG D W DG +
Sbjct: 365 RVTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQ-WKFPDGSFI 406
Score = 83.4 bits (197), Expect = 8e-16
Identities = 61/219 (27%), Positives = 93/219 (42%)
Frame = +2
Query: 128 KLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHF 307
KL+ +L GH V + + + P + S DK + W L Y + +GH
Sbjct: 237 KLKLSLTGHISTVRGVIVSTRSP-YLFSCGEDKQVKCWDL-----EYNKVIRHYHGHLSA 290
Query: 308 ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSR 487
+ + L + ++ S D T R+WD+ + HT V +V QI++GS
Sbjct: 291 VYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSH 350
Query: 488 DKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLK 667
D TI+LW+ +A K + H V V P H + G +K W +
Sbjct: 351 DTTIRLWDLVAG-KTRVTLTNHKKSVRAVVLHPRHYT---FASGSPDNIKQWKFPDGSFI 406
Query: 668 INHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDG 784
N GH+ +NT+TV+ DG L SG + LWD G
Sbjct: 407 QNLSGHNAIINTLTVNSDGVL-VSGADNGTMHLWDWRTG 444
Score = 62.5 bits (145), Expect = 2e-09
Identities = 40/133 (30%), Positives = 62/133 (46%)
Frame = +2
Query: 398 KTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVR 577
K R H V +A N+ V+GS D+TIK+W+ LA K + GH V V
Sbjct: 195 KLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWD-LASGKLKLSLTGHISTVRGVI 253
Query: 578 FSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMX 757
S +P + SCG D+ VK W L K+ ++ GH + + + P + + +D
Sbjct: 254 VSTR--SPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDST 311
Query: 758 AMLWDLNDGKHLH 796
A +WD+ +H
Sbjct: 312 ARIWDVRTKASVH 324
Score = 60.1 bits (139), Expect = 9e-09
Identities = 44/175 (25%), Positives = 85/175 (48%), Gaps = 2/175 (1%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYP--DMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGH 298
L+ +R ++G ++ + +P D++++ SRD T +W + + + L GH
Sbjct: 275 LEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVH-----TLSGH 329
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVS 478
++ ++ V + ++GS D T+RLWDL AGKT +H K V +V + S
Sbjct: 330 TNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPRHYTFAS 389
Query: 479 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVW 643
GS D IK W + + GH+ ++ + +++ ++VS + T+ +W
Sbjct: 390 GSPD-NIKQWK-FPDGSFIQNLSGHNAIINTLTV---NSDGVLVSGADNGTMHLW 439
>X70476-1|CAA49900.1| 906|Homo sapiens subunit of coatomer complex
protein.
Length = 906
Score = 87.4 bits (207), Expect = 5e-17
Identities = 54/186 (29%), Positives = 95/186 (51%), Gaps = 4/186 (2%)
Frame = +2
Query: 122 TLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHS 301
TL+ H+ ++ IA +P P IL+SS D + +W + + Q GH+
Sbjct: 88 TLERVHMFEAHSDYIRCIAVHPTQP-FILTSSDDMLIKLWDW---DKKWSCSQV-FEGHT 142
Query: 302 HFISDVVLS-SDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAF--SVDNRQI 472
H++ +V++ D N S S D+T+++W L + E H K V + + D +
Sbjct: 143 HYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYL 202
Query: 473 VSGSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 649
+SG+ D+ +K+W+ + C T++ GH+ VSC F P PII++ D TV++WH
Sbjct: 203 ISGADDRLVKIWDYQNKTCVQTLE--GHAQNVSCASFHPEL--PIIITGSEDGTVRIWHS 258
Query: 650 TNCKLK 667
+ +L+
Sbjct: 259 STYRLE 264
Score = 74.5 bits (175), Expect = 4e-13
Identities = 43/160 (26%), Positives = 73/160 (45%), Gaps = 2/160 (1%)
Frame = +2
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDL-AAGKTTRRFEDHTKDVLSVAFSV-DNRQ 469
HS +I + + + L+ S D ++LWD ++ FE HT V+ + + DN Q
Sbjct: 98 HSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQ 157
Query: 470 IVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 649
S S D+TIK+W L +GH V+C+ + P ++S DR VK+W
Sbjct: 158 FASASLDRTIKVWQ-LGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDY 216
Query: 650 TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
N GH+ ++ + P+ + +G +D +W
Sbjct: 217 QNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIW 256
>BC000326-1|AAH00326.1| 906|Homo sapiens coatomer protein complex,
subunit beta 2 (beta prime) protein.
Length = 906
Score = 87.4 bits (207), Expect = 5e-17
Identities = 54/186 (29%), Positives = 95/186 (51%), Gaps = 4/186 (2%)
Frame = +2
Query: 122 TLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHS 301
TL+ H+ ++ IA +P P IL+SS D + +W + + Q GH+
Sbjct: 88 TLERVHMFEAHSDYIRCIAVHPTQP-FILTSSDDMLIKLWDW---DKKWSCSQV-FEGHT 142
Query: 302 HFISDVVLS-SDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAF--SVDNRQI 472
H++ +V++ D N S S D+T+++W L + E H K V + + D +
Sbjct: 143 HYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYL 202
Query: 473 VSGSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 649
+SG+ D+ +K+W+ + C T++ GH+ VSC F P PII++ D TV++WH
Sbjct: 203 ISGADDRLVKIWDYQNKTCVQTLE--GHAQNVSCASFHPEL--PIIITGSEDGTVRIWHS 258
Query: 650 TNCKLK 667
+ +L+
Sbjct: 259 STYRLE 264
Score = 74.5 bits (175), Expect = 4e-13
Identities = 43/160 (26%), Positives = 73/160 (45%), Gaps = 2/160 (1%)
Frame = +2
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDL-AAGKTTRRFEDHTKDVLSVAFSV-DNRQ 469
HS +I + + + L+ S D ++LWD ++ FE HT V+ + + DN Q
Sbjct: 98 HSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQ 157
Query: 470 IVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 649
S S D+TIK+W L +GH V+C+ + P ++S DR VK+W
Sbjct: 158 FASASLDRTIKVWQ-LGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDY 216
Query: 650 TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
N GH+ ++ + P+ + +G +D +W
Sbjct: 217 QNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIW 256
>BC150255-1|AAI50256.1| 1237|Homo sapiens apoptotic peptidase
activating factor 1 protein.
Length = 1237
Score = 87.0 bits (206), Expect = 7e-17
Identities = 50/160 (31%), Positives = 79/160 (49%), Gaps = 1/160 (0%)
Frame = +2
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H+ + S DG S DKTL+++ G+ + H +VL AFS D+R I
Sbjct: 603 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 662
Query: 476 SGSRDKTIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
+ S DK +K+WN++ E +T D HS+ V+C F+ + + ++ + D +K+W L
Sbjct: 663 TCSVDKKVKIWNSMTGELVHTY--DEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN 720
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ + GH+ +N SPD L AS D LWD
Sbjct: 721 QKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWD 760
Score = 66.5 bits (155), Expect = 1e-10
Identities = 57/205 (27%), Positives = 96/205 (46%), Gaps = 10/205 (4%)
Frame = +2
Query: 161 WVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGN 340
W Q + K ++SSS D + VW D+ + L GH + D L +
Sbjct: 996 WHIQFTADEK---TLISSSDDAEIQVWNWQLDKCIF------LRGHQETVKDFRLLKNSR 1046
Query: 341 YALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN-TL 517
LS S+D T+++W++ G + F H VLS S D + S S DKT K+W+ L
Sbjct: 1047 L-LSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDL 1105
Query: 518 AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR-TVKVWHLTNCKL-----KINHL 679
+ ++ GH+ V C FS + +++ G D +++W+++N +L ++
Sbjct: 1106 LLPLHELR--GHNGCVRCSAFS---VDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEE 1160
Query: 680 G---HSGYLNTVTVSPDGSLCASGG 745
G H G++ + SPDG + S G
Sbjct: 1161 GAATHGGWVTDLCFSPDGKMLISAG 1185
Score = 58.0 bits (134), Expect = 4e-08
Identities = 39/158 (24%), Positives = 71/158 (44%), Gaps = 1/158 (0%)
Frame = +2
Query: 308 ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSR 487
+S LS Y G + + + +L + + H K V + F+ D + ++S S
Sbjct: 953 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 1012
Query: 488 DKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKL 664
D I++WN L +C + GH + V R N ++S +D TVKVW++
Sbjct: 1013 DAEIQVWNWQLDKCIFL---RGHQETVKDFRLLKNSR---LLSWSFDGTVKVWNIITGNK 1066
Query: 665 KINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLN 778
+ + + H G + + +S D + +S D A +W +
Sbjct: 1067 EKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFD 1104
Score = 57.6 bits (133), Expect = 5e-08
Identities = 39/121 (32%), Positives = 57/121 (47%), Gaps = 2/121 (1%)
Frame = +2
Query: 422 HTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANP 601
HT V FS D ++I S DKT++++ K ++ H D V C FS + +
Sbjct: 603 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKL-LEIKAHEDEVLCCAFSTD--DR 659
Query: 602 IIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTV--TVSPDGSLCASGGKDMXAMLWDL 775
I +C D+ VK+W+ +L + HS +N T S L A+G D LWDL
Sbjct: 660 FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDL 719
Query: 776 N 778
N
Sbjct: 720 N 720
Score = 53.2 bits (122), Expect = 1e-06
Identities = 51/212 (24%), Positives = 90/212 (42%), Gaps = 14/212 (6%)
Frame = +2
Query: 179 TNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGS 358
TN + ++ + S D L +W L + E + ++GH++ ++ S D S S
Sbjct: 697 TNSSHHLLLATGSSDCFLKLWDLNQKEC-----RNTMFGHTNSVNHCRFSPDDKLLASCS 751
Query: 359 WDKTLRLWDLAAGKTTR---------RFEDHTKD----VLSVAFSVDNRQIVSGSRDKTI 499
D TL+LWD + + ED +D V ++S D +I+ +++K I
Sbjct: 752 ADGTLKLWDATSANERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNK-I 810
Query: 500 KLWNTLAECKYTIQDDGHSDWVSCVRFSP-NHANPIIVSCGWDRTVKVWHLTNCKLKINH 676
L++ GH + FSP NH + +S V++W+ + +
Sbjct: 811 FLFDIHTSGLLGEIHTGHHSTIQYCDFSPQNHLAVVALS---QYCVELWNTDSRSKVADC 867
Query: 677 LGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
GH +++ V SPDGS + D LW+
Sbjct: 868 RGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWE 899
Score = 52.0 bits (119), Expect = 2e-06
Identities = 44/179 (24%), Positives = 80/179 (44%), Gaps = 1/179 (0%)
Frame = +2
Query: 263 NYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLS 442
N I Q R + H + + ++D +S S D +++W+ K H + V
Sbjct: 981 NNRIFQSR-FQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIF-LRGHQETVKD 1038
Query: 443 VAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGW 622
+ N +++S S D T+K+WN + K +SC +H S
Sbjct: 1039 FRL-LKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSC---DISHDATKFSSTSA 1094
Query: 623 DRTVKVWHLTNCKLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
D+T K+W + L ++ L GH+G + S D +L A+G + +W++++G+ LH
Sbjct: 1095 DKTAKIWSF-DLLLPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLH 1152
Score = 37.1 bits (82), Expect = 0.073
Identities = 22/79 (27%), Positives = 31/79 (39%)
Frame = +2
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI 472
GH I S + A+ + LW+ + H V V FS D
Sbjct: 827 GHHSTIQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSF 886
Query: 473 VSGSRDKTIKLWNTLAECK 529
++ S D+TI+LW T CK
Sbjct: 887 LTSSDDQTIRLWETKKVCK 905
>BC117246-1|AAI17247.1| 707|Homo sapiens F-box and WD repeat domain
containing 7 protein.
Length = 707
Score = 87.0 bits (206), Expect = 7e-17
Identities = 68/227 (29%), Positives = 107/227 (47%), Gaps = 3/227 (1%)
Frame = +2
Query: 122 TLKLRGTLRGHNG--WVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
T K TL GH G W +Q+ N +I+S S D+TL VW E + LYG
Sbjct: 410 TGKCLRTLVGHTGGVWSSQMRDN-----IIISGSTDRTLKVWNAETGECIH-----TLYG 459
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H+ + + L +SGS D TLR+WD+ G+ H V V + D R++V
Sbjct: 460 HTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQY--DGRRVV 515
Query: 476 SGSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
SG+ D +K+W+ E C +T+Q GH++ V ++F H +VS D +++VW +
Sbjct: 516 SGAYDFMVKVWDPETETCLHTLQ--GHTNRVYSLQFDGIH----VVSGSLDTSIRVWDVE 569
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
GH + + + ++ SG D +WD+ G+ L
Sbjct: 570 TGNCIHTLTGHQSLTSGMELK--DNILVSGNADSTVKIWDIKTGQCL 614
Score = 76.6 bits (180), Expect = 1e-13
Identities = 57/173 (32%), Positives = 77/173 (44%), Gaps = 1/173 (0%)
Frame = +2
Query: 281 KRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVD 460
K L GH + L GN +SGS D TL++W GK R HT V S D
Sbjct: 374 KVLKGHDDHVI-TCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMR-D 431
Query: 461 NRQIVSGSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVK 637
N I+SGS D+T+K+WN EC +T+ GH+ V C+ +VS D T++
Sbjct: 432 N-IIISGSTDRTLKVWNAETGECIHTLY--GHTSTVRCMHLHEKR----VVSGSRDATLR 484
Query: 638 VWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
VW + + +GH + V DG SG D +WD LH
Sbjct: 485 VWDIETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDPETETCLH 535
Score = 72.5 bits (170), Expect = 2e-12
Identities = 63/228 (27%), Positives = 102/228 (44%), Gaps = 2/228 (0%)
Frame = +2
Query: 116 SETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
+ET + TL GH V + + K ++S SRD TL VW + + + L G
Sbjct: 448 AETGECIHTLYGHTSTVRCMHLHEK---RVVSGSRDATLRVWDIETGQCLHV-----LMG 499
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H + V DG +SG++D +++WD + HT V S+ F D +V
Sbjct: 500 HVAAVRCV--QYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVV 555
Query: 476 SGSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
SGS D +I++W+ C +T+ GH S + N I+VS D TVK+W +
Sbjct: 556 SGSLDTSIRVWDVETGNCIHTL--TGHQSLTSGMELKDN----ILVSGNADSTVKIWDIK 609
Query: 653 NCKLKINHLGHSGYLNTVT-VSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ G + + + VT + + + + D LWDL G+ +
Sbjct: 610 TGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFI 657
Score = 65.7 bits (153), Expect = 2e-10
Identities = 44/162 (27%), Positives = 79/162 (48%), Gaps = 7/162 (4%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNR 466
L GH++ + L DG + +SGS D ++R+WD+ G H L+ + +
Sbjct: 537 LQGHTNRVYS--LQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS--LTSGMELKDN 592
Query: 467 QIVSGSRDKTIKLWN-TLAECKYTIQ-DDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKV 640
+VSG+ D T+K+W+ +C T+Q + H V+C++F+ N +++ D TVK+
Sbjct: 593 ILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKN----FVITSSDDGTVKL 648
Query: 641 WHLTNCKLKINHL-----GHSGYLNTVTVSPDGSLCASGGKD 751
W L + N + G G + + S +CA G ++
Sbjct: 649 WDLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRN 690
>BC117244-1|AAI17245.1| 707|Homo sapiens F-box and WD repeat domain
containing 7 protein.
Length = 707
Score = 87.0 bits (206), Expect = 7e-17
Identities = 68/227 (29%), Positives = 107/227 (47%), Gaps = 3/227 (1%)
Frame = +2
Query: 122 TLKLRGTLRGHNG--WVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
T K TL GH G W +Q+ N +I+S S D+TL VW E + LYG
Sbjct: 410 TGKCLRTLVGHTGGVWSSQMRDN-----IIISGSTDRTLKVWNAETGECIH-----TLYG 459
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H+ + + L +SGS D TLR+WD+ G+ H V V + D R++V
Sbjct: 460 HTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQY--DGRRVV 515
Query: 476 SGSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
SG+ D +K+W+ E C +T+Q GH++ V ++F H +VS D +++VW +
Sbjct: 516 SGAYDFMVKVWDPETETCLHTLQ--GHTNRVYSLQFDGIH----VVSGSLDTSIRVWDVE 569
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
GH + + + ++ SG D +WD+ G+ L
Sbjct: 570 TGNCIHTLTGHQSLTSGMELK--DNILVSGNADSTVKIWDIKTGQCL 614
Score = 76.6 bits (180), Expect = 1e-13
Identities = 57/173 (32%), Positives = 77/173 (44%), Gaps = 1/173 (0%)
Frame = +2
Query: 281 KRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVD 460
K L GH + L GN +SGS D TL++W GK R HT V S D
Sbjct: 374 KVLKGHDDHVI-TCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMR-D 431
Query: 461 NRQIVSGSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVK 637
N I+SGS D+T+K+WN EC +T+ GH+ V C+ +VS D T++
Sbjct: 432 N-IIISGSTDRTLKVWNAETGECIHTLY--GHTSTVRCMHLHEKR----VVSGSRDATLR 484
Query: 638 VWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
VW + + +GH + V DG SG D +WD LH
Sbjct: 485 VWDIETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDPETETCLH 535
Score = 72.5 bits (170), Expect = 2e-12
Identities = 63/228 (27%), Positives = 102/228 (44%), Gaps = 2/228 (0%)
Frame = +2
Query: 116 SETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
+ET + TL GH V + + K ++S SRD TL VW + + + L G
Sbjct: 448 AETGECIHTLYGHTSTVRCMHLHEK---RVVSGSRDATLRVWDIETGQCLHV-----LMG 499
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H + V DG +SG++D +++WD + HT V S+ F D +V
Sbjct: 500 HVAAVRCV--QYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVV 555
Query: 476 SGSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
SGS D +I++W+ C +T+ GH S + N I+VS D TVK+W +
Sbjct: 556 SGSLDTSIRVWDVETGNCIHTL--TGHQSLTSGMELKDN----ILVSGNADSTVKIWDIK 609
Query: 653 NCKLKINHLGHSGYLNTVT-VSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ G + + + VT + + + + D LWDL G+ +
Sbjct: 610 TGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFI 657
Score = 65.7 bits (153), Expect = 2e-10
Identities = 44/162 (27%), Positives = 79/162 (48%), Gaps = 7/162 (4%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNR 466
L GH++ + L DG + +SGS D ++R+WD+ G H L+ + +
Sbjct: 537 LQGHTNRVYS--LQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS--LTSGMELKDN 592
Query: 467 QIVSGSRDKTIKLWN-TLAECKYTIQ-DDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKV 640
+VSG+ D T+K+W+ +C T+Q + H V+C++F+ N +++ D TVK+
Sbjct: 593 ILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKN----FVITSSDDGTVKL 648
Query: 641 WHLTNCKLKINHL-----GHSGYLNTVTVSPDGSLCASGGKD 751
W L + N + G G + + S +CA G ++
Sbjct: 649 WDLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRN 690
>BC037320-1|AAH37320.1| 621|Homo sapiens FBXW7 protein protein.
Length = 621
Score = 87.0 bits (206), Expect = 7e-17
Identities = 68/227 (29%), Positives = 107/227 (47%), Gaps = 3/227 (1%)
Frame = +2
Query: 122 TLKLRGTLRGHNG--WVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
T K TL GH G W +Q+ N +I+S S D+TL VW E + LYG
Sbjct: 324 TGKCLRTLVGHTGGVWSSQMRDN-----IIISGSTDRTLKVWNAETGECIH-----TLYG 373
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H+ + + L +SGS D TLR+WD+ G+ H V V + D R++V
Sbjct: 374 HTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVRY--DGRRVV 429
Query: 476 SGSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
SG+ D +K+W+ E C +T+Q GH++ V ++F H +VS D +++VW +
Sbjct: 430 SGAYDFMVKVWDPETETCLHTLQ--GHTNRVYSLQFDGIH----VVSGSLDTSIRVWDVE 483
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
GH + + + ++ SG D +WD+ G+ L
Sbjct: 484 TGNCIHTLTGHQSLTSGMELK--DNILVSGNADSTVKIWDIKTGQCL 528
Score = 76.6 bits (180), Expect = 1e-13
Identities = 57/173 (32%), Positives = 77/173 (44%), Gaps = 1/173 (0%)
Frame = +2
Query: 281 KRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVD 460
K L GH + L GN +SGS D TL++W GK R HT V S D
Sbjct: 288 KVLNGHDDHVI-TCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMR-D 345
Query: 461 NRQIVSGSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVK 637
N I+SGS D+T+K+WN EC +T+ GH+ V C+ +VS D T++
Sbjct: 346 N-IIISGSTDRTLKVWNAETGECIHTLY--GHTSTVRCMHLHEKR----VVSGSRDATLR 398
Query: 638 VWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
VW + + +GH + V DG SG D +WD LH
Sbjct: 399 VWDIETGQCLHVLMGHVAAVRCVRY--DGRRVVSGAYDFMVKVWDPETETCLH 449
Score = 72.1 bits (169), Expect = 2e-12
Identities = 63/228 (27%), Positives = 102/228 (44%), Gaps = 2/228 (0%)
Frame = +2
Query: 116 SETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
+ET + TL GH V + + K ++S SRD TL VW + + + L G
Sbjct: 362 AETGECIHTLYGHTSTVRCMHLHEK---RVVSGSRDATLRVWDIETGQCLHV-----LMG 413
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H + V DG +SG++D +++WD + HT V S+ F D +V
Sbjct: 414 HVAAVRCV--RYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVV 469
Query: 476 SGSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
SGS D +I++W+ C +T+ GH S + N I+VS D TVK+W +
Sbjct: 470 SGSLDTSIRVWDVETGNCIHTL--TGHQSLTSGMELKDN----ILVSGNADSTVKIWDIK 523
Query: 653 NCKLKINHLGHSGYLNTVT-VSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ G + + + VT + + + + D LWDL G+ +
Sbjct: 524 TGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFI 571
Score = 65.7 bits (153), Expect = 2e-10
Identities = 44/162 (27%), Positives = 79/162 (48%), Gaps = 7/162 (4%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNR 466
L GH++ + L DG + +SGS D ++R+WD+ G H L+ + +
Sbjct: 451 LQGHTNRVYS--LQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS--LTSGMELKDN 506
Query: 467 QIVSGSRDKTIKLWN-TLAECKYTIQ-DDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKV 640
+VSG+ D T+K+W+ +C T+Q + H V+C++F+ N +++ D TVK+
Sbjct: 507 ILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKN----FVITSSDDGTVKL 562
Query: 641 WHLTNCKLKINHL-----GHSGYLNTVTVSPDGSLCASGGKD 751
W L + N + G G + + S +CA G ++
Sbjct: 563 WDLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRN 604
>AY049984-1|AAL07271.1| 707|Homo sapiens F-box protein CDC4 protein.
Length = 707
Score = 87.0 bits (206), Expect = 7e-17
Identities = 68/227 (29%), Positives = 107/227 (47%), Gaps = 3/227 (1%)
Frame = +2
Query: 122 TLKLRGTLRGHNG--WVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
T K TL GH G W +Q+ N +I+S S D+TL VW E + LYG
Sbjct: 410 TGKCLRTLVGHTGGVWSSQMRDN-----IIISGSTDRTLKVWNAETGECIH-----TLYG 459
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H+ + + L +SGS D TLR+WD+ G+ H V V + D R++V
Sbjct: 460 HTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQY--DGRRVV 515
Query: 476 SGSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
SG+ D +K+W+ E C +T+Q GH++ V ++F H +VS D +++VW +
Sbjct: 516 SGAYDFMVKVWDPETETCLHTLQ--GHTNRVYSLQFDGIH----VVSGSLDTSIRVWDVE 569
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
GH + + + ++ SG D +WD+ G+ L
Sbjct: 570 TGNCIHTLTGHQSLTSGMELK--DNILVSGNADSTVKIWDIKTGQCL 614
Score = 76.6 bits (180), Expect = 1e-13
Identities = 57/173 (32%), Positives = 77/173 (44%), Gaps = 1/173 (0%)
Frame = +2
Query: 281 KRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVD 460
K L GH + L GN +SGS D TL++W GK R HT V S D
Sbjct: 374 KVLKGHDDHVI-TCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMR-D 431
Query: 461 NRQIVSGSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVK 637
N I+SGS D+T+K+WN EC +T+ GH+ V C+ +VS D T++
Sbjct: 432 N-IIISGSTDRTLKVWNAETGECIHTLY--GHTSTVRCMHLHEKR----VVSGSRDATLR 484
Query: 638 VWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
VW + + +GH + V DG SG D +WD LH
Sbjct: 485 VWDIETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDPETETCLH 535
Score = 72.5 bits (170), Expect = 2e-12
Identities = 63/228 (27%), Positives = 102/228 (44%), Gaps = 2/228 (0%)
Frame = +2
Query: 116 SETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
+ET + TL GH V + + K ++S SRD TL VW + + + L G
Sbjct: 448 AETGECIHTLYGHTSTVRCMHLHEK---RVVSGSRDATLRVWDIETGQCLHV-----LMG 499
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H + V DG +SG++D +++WD + HT V S+ F D +V
Sbjct: 500 HVAAVRCV--QYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVV 555
Query: 476 SGSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
SGS D +I++W+ C +T+ GH S + N I+VS D TVK+W +
Sbjct: 556 SGSLDTSIRVWDVETGNCIHTL--TGHQSLTSGMELKDN----ILVSGNADSTVKIWDIK 609
Query: 653 NCKLKINHLGHSGYLNTVT-VSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ G + + + VT + + + + D LWDL G+ +
Sbjct: 610 TGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFI 657
Score = 65.7 bits (153), Expect = 2e-10
Identities = 44/162 (27%), Positives = 79/162 (48%), Gaps = 7/162 (4%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNR 466
L GH++ + L DG + +SGS D ++R+WD+ G H L+ + +
Sbjct: 537 LQGHTNRVYS--LQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS--LTSGMELKDN 592
Query: 467 QIVSGSRDKTIKLWN-TLAECKYTIQ-DDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKV 640
+VSG+ D T+K+W+ +C T+Q + H V+C++F+ N +++ D TVK+
Sbjct: 593 ILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKN----FVITSSDDGTVKL 648
Query: 641 WHLTNCKLKINHL-----GHSGYLNTVTVSPDGSLCASGGKD 751
W L + N + G G + + S +CA G ++
Sbjct: 649 WDLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRN 690
>AY033553-1|AAK57547.1| 627|Homo sapiens F-box protein FBW7
protein.
Length = 627
Score = 87.0 bits (206), Expect = 7e-17
Identities = 68/227 (29%), Positives = 107/227 (47%), Gaps = 3/227 (1%)
Frame = +2
Query: 122 TLKLRGTLRGHNG--WVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
T K TL GH G W +Q+ N +I+S S D+TL VW E + LYG
Sbjct: 330 TGKCLRTLVGHTGGVWSSQMRDN-----IIISGSTDRTLKVWNAETGECIH-----TLYG 379
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H+ + + L +SGS D TLR+WD+ G+ H V V + D R++V
Sbjct: 380 HTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQY--DGRRVV 435
Query: 476 SGSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
SG+ D +K+W+ E C +T+Q GH++ V ++F H +VS D +++VW +
Sbjct: 436 SGAYDFMVKVWDPETETCLHTLQ--GHTNRVYSLQFDGIH----VVSGSLDTSIRVWDVE 489
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
GH + + + ++ SG D +WD+ G+ L
Sbjct: 490 TGNCIHTLTGHQSLTSGMELK--DNILVSGNADSTVKIWDIKTGQCL 534
Score = 76.6 bits (180), Expect = 1e-13
Identities = 57/173 (32%), Positives = 77/173 (44%), Gaps = 1/173 (0%)
Frame = +2
Query: 281 KRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVD 460
K L GH + L GN +SGS D TL++W GK R HT V S D
Sbjct: 294 KVLKGHDDHVI-TCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMR-D 351
Query: 461 NRQIVSGSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVK 637
N I+SGS D+T+K+WN EC +T+ GH+ V C+ +VS D T++
Sbjct: 352 N-IIISGSTDRTLKVWNAETGECIHTLY--GHTSTVRCMHLHEKR----VVSGSRDATLR 404
Query: 638 VWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
VW + + +GH + V DG SG D +WD LH
Sbjct: 405 VWDIETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDPETETCLH 455
Score = 72.5 bits (170), Expect = 2e-12
Identities = 63/228 (27%), Positives = 102/228 (44%), Gaps = 2/228 (0%)
Frame = +2
Query: 116 SETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
+ET + TL GH V + + K ++S SRD TL VW + + + L G
Sbjct: 368 AETGECIHTLYGHTSTVRCMHLHEK---RVVSGSRDATLRVWDIETGQCLHV-----LMG 419
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H + V DG +SG++D +++WD + HT V S+ F D +V
Sbjct: 420 HVAAVRCV--QYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVV 475
Query: 476 SGSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
SGS D +I++W+ C +T+ GH S + N I+VS D TVK+W +
Sbjct: 476 SGSLDTSIRVWDVETGNCIHTL--TGHQSLTSGMELKDN----ILVSGNADSTVKIWDIK 529
Query: 653 NCKLKINHLGHSGYLNTVT-VSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ G + + + VT + + + + D LWDL G+ +
Sbjct: 530 TGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFI 577
Score = 65.7 bits (153), Expect = 2e-10
Identities = 44/162 (27%), Positives = 79/162 (48%), Gaps = 7/162 (4%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNR 466
L GH++ + L DG + +SGS D ++R+WD+ G H L+ + +
Sbjct: 457 LQGHTNRVYS--LQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS--LTSGMELKDN 512
Query: 467 QIVSGSRDKTIKLWN-TLAECKYTIQ-DDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKV 640
+VSG+ D T+K+W+ +C T+Q + H V+C++F+ N +++ D TVK+
Sbjct: 513 ILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKN----FVITSSDDGTVKL 568
Query: 641 WHLTNCKLKINHL-----GHSGYLNTVTVSPDGSLCASGGKD 751
W L + N + G G + + S +CA G ++
Sbjct: 569 WDLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRN 610
>AY008274-1|AAG16640.1| 589|Homo sapiens F-box protein SEL10
protein.
Length = 589
Score = 87.0 bits (206), Expect = 7e-17
Identities = 68/227 (29%), Positives = 107/227 (47%), Gaps = 3/227 (1%)
Frame = +2
Query: 122 TLKLRGTLRGHNG--WVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
T K TL GH G W +Q+ N +I+S S D+TL VW E + LYG
Sbjct: 292 TGKCLRTLVGHTGGVWSSQMRDN-----IIISGSTDRTLKVWNAETGECIH-----TLYG 341
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H+ + + L +SGS D TLR+WD+ G+ H V V + D R++V
Sbjct: 342 HTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQY--DGRRVV 397
Query: 476 SGSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
SG+ D +K+W+ E C +T+Q GH++ V ++F H +VS D +++VW +
Sbjct: 398 SGAYDFMVKVWDPETETCLHTLQ--GHTNRVYSLQFDGIH----VVSGSLDTSIRVWDVE 451
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
GH + + + ++ SG D +WD+ G+ L
Sbjct: 452 TGNCIHTLTGHQSLTSGMELK--DNILVSGNADSTVKIWDIKTGQCL 496
Score = 76.6 bits (180), Expect = 1e-13
Identities = 57/173 (32%), Positives = 77/173 (44%), Gaps = 1/173 (0%)
Frame = +2
Query: 281 KRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVD 460
K L GH + L GN +SGS D TL++W GK R HT V S D
Sbjct: 256 KVLKGHDDHVI-TCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMR-D 313
Query: 461 NRQIVSGSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVK 637
N I+SGS D+T+K+WN EC +T+ GH+ V C+ +VS D T++
Sbjct: 314 N-IIISGSTDRTLKVWNAETGECIHTLY--GHTSTVRCMHLHEKR----VVSGSRDATLR 366
Query: 638 VWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
VW + + +GH + V DG SG D +WD LH
Sbjct: 367 VWDIETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDPETETCLH 417
Score = 72.5 bits (170), Expect = 2e-12
Identities = 63/228 (27%), Positives = 102/228 (44%), Gaps = 2/228 (0%)
Frame = +2
Query: 116 SETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
+ET + TL GH V + + K ++S SRD TL VW + + + L G
Sbjct: 330 AETGECIHTLYGHTSTVRCMHLHEK---RVVSGSRDATLRVWDIETGQCLHV-----LMG 381
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H + V DG +SG++D +++WD + HT V S+ F D +V
Sbjct: 382 HVAAVRCV--QYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVV 437
Query: 476 SGSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
SGS D +I++W+ C +T+ GH S + N I+VS D TVK+W +
Sbjct: 438 SGSLDTSIRVWDVETGNCIHTL--TGHQSLTSGMELKDN----ILVSGNADSTVKIWDIK 491
Query: 653 NCKLKINHLGHSGYLNTVT-VSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ G + + + VT + + + + D LWDL G+ +
Sbjct: 492 TGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFI 539
Score = 65.7 bits (153), Expect = 2e-10
Identities = 44/162 (27%), Positives = 79/162 (48%), Gaps = 7/162 (4%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNR 466
L GH++ + L DG + +SGS D ++R+WD+ G H L+ + +
Sbjct: 419 LQGHTNRVYS--LQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS--LTSGMELKDN 474
Query: 467 QIVSGSRDKTIKLWN-TLAECKYTIQ-DDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKV 640
+VSG+ D T+K+W+ +C T+Q + H V+C++F+ N +++ D TVK+
Sbjct: 475 ILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKN----FVITSSDDGTVKL 530
Query: 641 WHLTNCKLKINHL-----GHSGYLNTVTVSPDGSLCASGGKD 751
W L + N + G G + + S +CA G ++
Sbjct: 531 WDLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRN 572
>AK223449-1|BAD97169.1| 627|Homo sapiens F-box protein FBW7 isoform
2 variant protein.
Length = 627
Score = 87.0 bits (206), Expect = 7e-17
Identities = 68/227 (29%), Positives = 107/227 (47%), Gaps = 3/227 (1%)
Frame = +2
Query: 122 TLKLRGTLRGHNG--WVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
T K TL GH G W +Q+ N +I+S S D+TL VW E + LYG
Sbjct: 330 TGKCLRTLVGHTGGVWSSQMRDN-----IIISGSTDRTLKVWNAETGECIH-----TLYG 379
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H+ + + L +SGS D TLR+WD+ G+ H V V + D R++V
Sbjct: 380 HTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQY--DGRRVV 435
Query: 476 SGSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
SG+ D +K+W+ E C +T+Q GH++ V ++F H +VS D +++VW +
Sbjct: 436 SGAYDFMVKVWDPETETCLHTLQ--GHTNRVYSLQFDGIH----VVSGSLDTSIRVWDVE 489
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
GH + + + ++ SG D +WD+ G+ L
Sbjct: 490 TGNCIHTLTGHQSLTSGMELK--DNILVSGNADSTVKIWDIKTGQCL 534
Score = 76.6 bits (180), Expect = 1e-13
Identities = 57/173 (32%), Positives = 77/173 (44%), Gaps = 1/173 (0%)
Frame = +2
Query: 281 KRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVD 460
K L GH + L GN +SGS D TL++W GK R HT V S D
Sbjct: 294 KVLKGHDDHVI-TCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMR-D 351
Query: 461 NRQIVSGSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVK 637
N I+SGS D+T+K+WN EC +T+ GH+ V C+ +VS D T++
Sbjct: 352 N-IIISGSTDRTLKVWNAETGECIHTLY--GHTSTVRCMHLHEKR----VVSGSRDATLR 404
Query: 638 VWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
VW + + +GH + V DG SG D +WD LH
Sbjct: 405 VWDIETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDPETETCLH 455
Score = 72.5 bits (170), Expect = 2e-12
Identities = 63/228 (27%), Positives = 102/228 (44%), Gaps = 2/228 (0%)
Frame = +2
Query: 116 SETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
+ET + TL GH V + + K ++S SRD TL VW + + + L G
Sbjct: 368 AETGECIHTLYGHTSTVRCMHLHEK---RVVSGSRDATLRVWDIETGQCLHV-----LMG 419
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H + V DG +SG++D +++WD + HT V S+ F D +V
Sbjct: 420 HVAAVRCV--QYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVV 475
Query: 476 SGSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
SGS D +I++W+ C +T+ GH S + N I+VS D TVK+W +
Sbjct: 476 SGSLDTSIRVWDVETGNCIHTL--TGHQSLTSGMELKDN----ILVSGNADSTVKIWDIK 529
Query: 653 NCKLKINHLGHSGYLNTVT-VSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ G + + + VT + + + + D LWDL G+ +
Sbjct: 530 TGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFI 577
Score = 65.7 bits (153), Expect = 2e-10
Identities = 44/162 (27%), Positives = 79/162 (48%), Gaps = 7/162 (4%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNR 466
L GH++ + L DG + +SGS D ++R+WD+ G H L+ + +
Sbjct: 457 LQGHTNRVYS--LQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS--LTSGMELKDN 512
Query: 467 QIVSGSRDKTIKLWN-TLAECKYTIQ-DDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKV 640
+VSG+ D T+K+W+ +C T+Q + H V+C++F+ N +++ D TVK+
Sbjct: 513 ILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKN----FVITSSDDGTVKL 568
Query: 641 WHLTNCKLKINHL-----GHSGYLNTVTVSPDGSLCASGGKD 751
W L + N + G G + + S +CA G ++
Sbjct: 569 WDLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRN 610
>AK001933-1|BAA91986.1| 553|Homo sapiens protein ( Homo sapiens
cDNA FLJ11071 fis, clone PLACE1004937, moderately
similar to SEL-10 PROTEIN. ).
Length = 553
Score = 87.0 bits (206), Expect = 7e-17
Identities = 68/227 (29%), Positives = 107/227 (47%), Gaps = 3/227 (1%)
Frame = +2
Query: 122 TLKLRGTLRGHNG--WVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
T K TL GH G W +Q+ N +I+S S D+TL VW E + LYG
Sbjct: 256 TGKCLRTLVGHTGGVWSSQMRDN-----IIISGSTDRTLKVWNAETGECIH-----TLYG 305
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H+ + + L +SGS D TLR+WD+ G+ H V V + D R++V
Sbjct: 306 HTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQY--DGRRVV 361
Query: 476 SGSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
SG+ D +K+W+ E C +T+Q GH++ V ++F H +VS D +++VW +
Sbjct: 362 SGAYDFMVKVWDPETETCLHTLQ--GHTNRVYSLQFDGIH----VVSGSLDTSIRVWDVE 415
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
GH + + + ++ SG D +WD+ G+ L
Sbjct: 416 TGNCIHTLTGHQSLTSGMELK--DNILVSGNADSTVKIWDIKTGQCL 460
Score = 76.6 bits (180), Expect = 1e-13
Identities = 57/173 (32%), Positives = 77/173 (44%), Gaps = 1/173 (0%)
Frame = +2
Query: 281 KRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVD 460
K L GH + L GN +SGS D TL++W GK R HT V S D
Sbjct: 220 KVLKGHDDHVI-TCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMR-D 277
Query: 461 NRQIVSGSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVK 637
N I+SGS D+T+K+WN EC +T+ GH+ V C+ +VS D T++
Sbjct: 278 N-IIISGSTDRTLKVWNAETGECIHTLY--GHTSTVRCMHLHEKR----VVSGSRDATLR 330
Query: 638 VWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
VW + + +GH + V DG SG D +WD LH
Sbjct: 331 VWDIETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDPETETCLH 381
Score = 72.5 bits (170), Expect = 2e-12
Identities = 63/228 (27%), Positives = 102/228 (44%), Gaps = 2/228 (0%)
Frame = +2
Query: 116 SETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
+ET + TL GH V + + K ++S SRD TL VW + + + L G
Sbjct: 294 AETGECIHTLYGHTSTVRCMHLHEK---RVVSGSRDATLRVWDIETGQCLHV-----LMG 345
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H + V DG +SG++D +++WD + HT V S+ F D +V
Sbjct: 346 HVAAVRCV--QYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVV 401
Query: 476 SGSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
SGS D +I++W+ C +T+ GH S + N I+VS D TVK+W +
Sbjct: 402 SGSLDTSIRVWDVETGNCIHTL--TGHQSLTSGMELKDN----ILVSGNADSTVKIWDIK 455
Query: 653 NCKLKINHLGHSGYLNTVT-VSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ G + + + VT + + + + D LWDL G+ +
Sbjct: 456 TGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFI 503
Score = 65.7 bits (153), Expect = 2e-10
Identities = 44/162 (27%), Positives = 79/162 (48%), Gaps = 7/162 (4%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNR 466
L GH++ + L DG + +SGS D ++R+WD+ G H L+ + +
Sbjct: 383 LQGHTNRVYS--LQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS--LTSGMELKDN 438
Query: 467 QIVSGSRDKTIKLWN-TLAECKYTIQ-DDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKV 640
+VSG+ D T+K+W+ +C T+Q + H V+C++F+ N +++ D TVK+
Sbjct: 439 ILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKN----FVITSSDDGTVKL 494
Query: 641 WHLTNCKLKINHL-----GHSGYLNTVTVSPDGSLCASGGKD 751
W L + N + G G + + S +CA G ++
Sbjct: 495 WDLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRN 536
>AJ243048-1|CAB55588.1| 1248|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1248
Score = 87.0 bits (206), Expect = 7e-17
Identities = 50/160 (31%), Positives = 79/160 (49%), Gaps = 1/160 (0%)
Frame = +2
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H+ + S DG S DKTL+++ G+ + H +VL AFS D+R I
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 673
Query: 476 SGSRDKTIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
+ S DK +K+WN++ E +T D HS+ V+C F+ + + ++ + D +K+W L
Sbjct: 674 TCSVDKKVKIWNSMTGELVHTY--DEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN 731
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ + GH+ +N SPD L AS D LWD
Sbjct: 732 QKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWD 771
Score = 66.5 bits (155), Expect = 1e-10
Identities = 57/205 (27%), Positives = 96/205 (46%), Gaps = 10/205 (4%)
Frame = +2
Query: 161 WVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGN 340
W Q + K ++SSS D + VW D+ + L GH + D L +
Sbjct: 1007 WHIQFTADEK---TLISSSDDAEIQVWNWQLDKCIF------LRGHQETVKDFRLLKNSR 1057
Query: 341 YALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN-TL 517
LS S+D T+++W++ G + F H VLS S D + S S DKT K+W+ L
Sbjct: 1058 L-LSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDL 1116
Query: 518 AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR-TVKVWHLTNCKL-----KINHL 679
+ ++ GH+ V C FS + +++ G D +++W+++N +L ++
Sbjct: 1117 LLPLHELR--GHNGCVRCSAFS---VDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEE 1171
Query: 680 G---HSGYLNTVTVSPDGSLCASGG 745
G H G++ + SPDG + S G
Sbjct: 1172 GAATHGGWVTDLCFSPDGKMLISAG 1196
Score = 58.0 bits (134), Expect = 4e-08
Identities = 39/158 (24%), Positives = 71/158 (44%), Gaps = 1/158 (0%)
Frame = +2
Query: 308 ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSR 487
+S LS Y G + + + +L + + H K V + F+ D + ++S S
Sbjct: 964 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 1023
Query: 488 DKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKL 664
D I++WN L +C + GH + V R N ++S +D TVKVW++
Sbjct: 1024 DAEIQVWNWQLDKCIFL---RGHQETVKDFRLLKNSR---LLSWSFDGTVKVWNIITGNK 1077
Query: 665 KINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLN 778
+ + + H G + + +S D + +S D A +W +
Sbjct: 1078 EKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFD 1115
Score = 57.6 bits (133), Expect = 5e-08
Identities = 39/121 (32%), Positives = 57/121 (47%), Gaps = 2/121 (1%)
Frame = +2
Query: 422 HTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANP 601
HT V FS D ++I S DKT++++ K ++ H D V C FS + +
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKL-LEIKAHEDEVLCCAFSTD--DR 670
Query: 602 IIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTV--TVSPDGSLCASGGKDMXAMLWDL 775
I +C D+ VK+W+ +L + HS +N T S L A+G D LWDL
Sbjct: 671 FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDL 730
Query: 776 N 778
N
Sbjct: 731 N 731
Score = 53.2 bits (122), Expect = 1e-06
Identities = 51/212 (24%), Positives = 90/212 (42%), Gaps = 14/212 (6%)
Frame = +2
Query: 179 TNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGS 358
TN + ++ + S D L +W L + E + ++GH++ ++ S D S S
Sbjct: 708 TNSSHHLLLATGSSDCFLKLWDLNQKEC-----RNTMFGHTNSVNHCRFSPDDKLLASCS 762
Query: 359 WDKTLRLWDLAAGKTTR---------RFEDHTKD----VLSVAFSVDNRQIVSGSRDKTI 499
D TL+LWD + + ED +D V ++S D +I+ +++K I
Sbjct: 763 ADGTLKLWDATSANERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNK-I 821
Query: 500 KLWNTLAECKYTIQDDGHSDWVSCVRFSP-NHANPIIVSCGWDRTVKVWHLTNCKLKINH 676
L++ GH + FSP NH + +S V++W+ + +
Sbjct: 822 FLFDIHTSGLLGEIHTGHHSTIQYCDFSPQNHLAVVALS---QYCVELWNTDSRSKVADC 878
Query: 677 LGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
GH +++ V SPDGS + D LW+
Sbjct: 879 RGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWE 910
Score = 52.0 bits (119), Expect = 2e-06
Identities = 44/179 (24%), Positives = 80/179 (44%), Gaps = 1/179 (0%)
Frame = +2
Query: 263 NYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLS 442
N I Q R + H + + ++D +S S D +++W+ K H + V
Sbjct: 992 NNRIFQSR-FQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIF-LRGHQETVKD 1049
Query: 443 VAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGW 622
+ N +++S S D T+K+WN + K +SC +H S
Sbjct: 1050 FRL-LKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSC---DISHDATKFSSTSA 1105
Query: 623 DRTVKVWHLTNCKLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
D+T K+W + L ++ L GH+G + S D +L A+G + +W++++G+ LH
Sbjct: 1106 DKTAKIWSF-DLLLPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLH 1163
Score = 37.1 bits (82), Expect = 0.073
Identities = 22/79 (27%), Positives = 31/79 (39%)
Frame = +2
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI 472
GH I S + A+ + LW+ + H V V FS D
Sbjct: 838 GHHSTIQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSF 897
Query: 473 VSGSRDKTIKLWNTLAECK 529
++ S D+TI+LW T CK
Sbjct: 898 LTSSDDQTIRLWETKKVCK 916
>AJ243009-1|CAB55585.1| 1248|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1248
Score = 87.0 bits (206), Expect = 7e-17
Identities = 50/160 (31%), Positives = 79/160 (49%), Gaps = 1/160 (0%)
Frame = +2
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H+ + S DG S DKTL+++ G+ + H +VL AFS D+R I
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 673
Query: 476 SGSRDKTIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
+ S DK +K+WN++ E +T D HS+ V+C F+ + + ++ + D +K+W L
Sbjct: 674 TCSVDKKVKIWNSMTGELVHTY--DEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN 731
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ + GH+ +N SPD L AS D LWD
Sbjct: 732 QKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWD 771
Score = 66.5 bits (155), Expect = 1e-10
Identities = 57/205 (27%), Positives = 96/205 (46%), Gaps = 10/205 (4%)
Frame = +2
Query: 161 WVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGN 340
W Q + K ++SSS D + VW D+ + L GH + D L +
Sbjct: 1007 WHIQFTADEK---TLISSSDDAEIQVWNWQLDKCIF------LRGHQETVKDFRLLKNSR 1057
Query: 341 YALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN-TL 517
LS S+D T+++W++ G + F H VLS S D + S S DKT K+W+ L
Sbjct: 1058 L-LSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDL 1116
Query: 518 AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR-TVKVWHLTNCKL-----KINHL 679
+ ++ GH+ V C FS + +++ G D +++W+++N +L ++
Sbjct: 1117 LLPLHELR--GHNGCVRCSAFS---VDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEE 1171
Query: 680 G---HSGYLNTVTVSPDGSLCASGG 745
G H G++ + SPDG + S G
Sbjct: 1172 GAATHGGWVTDLCFSPDGKMLISAG 1196
Score = 58.0 bits (134), Expect = 4e-08
Identities = 39/158 (24%), Positives = 71/158 (44%), Gaps = 1/158 (0%)
Frame = +2
Query: 308 ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSR 487
+S LS Y G + + + +L + + H K V + F+ D + ++S S
Sbjct: 964 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 1023
Query: 488 DKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKL 664
D I++WN L +C + GH + V R N ++S +D TVKVW++
Sbjct: 1024 DAEIQVWNWQLDKCIFL---RGHQETVKDFRLLKNSR---LLSWSFDGTVKVWNIITGNK 1077
Query: 665 KINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLN 778
+ + + H G + + +S D + +S D A +W +
Sbjct: 1078 EKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFD 1115
Score = 57.6 bits (133), Expect = 5e-08
Identities = 39/121 (32%), Positives = 57/121 (47%), Gaps = 2/121 (1%)
Frame = +2
Query: 422 HTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANP 601
HT V FS D ++I S DKT++++ K ++ H D V C FS + +
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKL-LEIKAHEDEVLCCAFSTD--DR 670
Query: 602 IIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTV--TVSPDGSLCASGGKDMXAMLWDL 775
I +C D+ VK+W+ +L + HS +N T S L A+G D LWDL
Sbjct: 671 FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDL 730
Query: 776 N 778
N
Sbjct: 731 N 731
Score = 52.0 bits (119), Expect = 2e-06
Identities = 51/212 (24%), Positives = 89/212 (41%), Gaps = 14/212 (6%)
Frame = +2
Query: 179 TNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGS 358
TN + ++ + S D L +W L + E + ++GH++ ++ S D S S
Sbjct: 708 TNSSHHLLLATGSSDCFLKLWDLNQKEC-----RNTMFGHTNSVNHCRFSPDDKLLASCS 762
Query: 359 WDKTLRLWDLAAGKTTR---------RFEDHTKD----VLSVAFSVDNRQIVSGSRDKTI 499
D TL+LWD + + ED +D V ++S D +I+ +++K I
Sbjct: 763 ADGTLKLWDATSANERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNK-I 821
Query: 500 KLWNTLAECKYTIQDDGHSDWVSCVRFSP-NHANPIIVSCGWDRTVKVWHLTNCKLKINH 676
L+ GH + FSP NH + +S V++W+ + +
Sbjct: 822 FLFAIHTSGLLGEIHTGHHSTIQYCDFSPQNHLAVVALS---QYCVELWNTDSRSKVADC 878
Query: 677 LGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
GH +++ V SPDGS + D LW+
Sbjct: 879 RGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWE 910
Score = 52.0 bits (119), Expect = 2e-06
Identities = 44/179 (24%), Positives = 80/179 (44%), Gaps = 1/179 (0%)
Frame = +2
Query: 263 NYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLS 442
N I Q R + H + + ++D +S S D +++W+ K H + V
Sbjct: 992 NNRIFQSR-FQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIF-LRGHQETVKD 1049
Query: 443 VAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGW 622
+ N +++S S D T+K+WN + K +SC +H S
Sbjct: 1050 FRL-LKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSC---DISHDATKFSSTSA 1105
Query: 623 DRTVKVWHLTNCKLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
D+T K+W + L ++ L GH+G + S D +L A+G + +W++++G+ LH
Sbjct: 1106 DKTAKIWSF-DLLLPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLH 1163
Score = 37.1 bits (82), Expect = 0.073
Identities = 22/79 (27%), Positives = 31/79 (39%)
Frame = +2
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI 472
GH I S + A+ + LW+ + H V V FS D
Sbjct: 838 GHHSTIQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSF 897
Query: 473 VSGSRDKTIKLWNTLAECK 529
++ S D+TI+LW T CK
Sbjct: 898 LTSSDDQTIRLWETKKVCK 916
>AJ243006-1|CAB55582.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 87.0 bits (206), Expect = 7e-17
Identities = 50/160 (31%), Positives = 79/160 (49%), Gaps = 1/160 (0%)
Frame = +2
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H+ + S DG S DKTL+++ G+ + H +VL AFS D+R I
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 673
Query: 476 SGSRDKTIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
+ S DK +K+WN++ E +T D HS+ V+C F+ + + ++ + D +K+W L
Sbjct: 674 TCSVDKKVKIWNSMTGELVHTY--DEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN 731
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ + GH+ +N SPD L AS D LWD
Sbjct: 732 QKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWD 771
Score = 65.7 bits (153), Expect = 2e-10
Identities = 57/205 (27%), Positives = 96/205 (46%), Gaps = 10/205 (4%)
Frame = +2
Query: 161 WVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGN 340
W Q + K ++SSS D + VW D+ + L GH + D L +
Sbjct: 964 WRIQFTADEK---TLISSSDDAEIQVWNWQLDKCIF------LRGHQETVKDFRLLKNPR 1014
Query: 341 YALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN-TL 517
LS S+D T+++W++ G + F H VLS S D + S S DKT K+W+ L
Sbjct: 1015 L-LSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDL 1073
Query: 518 AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR-TVKVWHLTNCKL-----KINHL 679
+ ++ GH+ V C FS + +++ G D +++W+++N +L ++
Sbjct: 1074 LLPLHELR--GHNGCVRCSAFS---VDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEE 1128
Query: 680 G---HSGYLNTVTVSPDGSLCASGG 745
G H G++ + SPDG + S G
Sbjct: 1129 GAATHGGWVTDLCFSPDGKMLISAG 1153
Score = 60.5 bits (140), Expect = 7e-09
Identities = 40/158 (25%), Positives = 72/158 (45%), Gaps = 1/158 (0%)
Frame = +2
Query: 308 ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSR 487
+S LS Y G + + + +L + + H K V + F+ D + ++S S
Sbjct: 921 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWRIQFTADEKTLISSSD 980
Query: 488 DKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKL 664
D I++WN L +C + GH + V R N P ++S +D TVKVW++
Sbjct: 981 DAEIQVWNWQLDKCIFL---RGHQETVKDFRLLKN---PRLLSWSFDGTVKVWNIITGNK 1034
Query: 665 KINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLN 778
+ + + H G + + +S D + +S D A +W +
Sbjct: 1035 EKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFD 1072
Score = 57.6 bits (133), Expect = 5e-08
Identities = 39/121 (32%), Positives = 57/121 (47%), Gaps = 2/121 (1%)
Frame = +2
Query: 422 HTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANP 601
HT V FS D ++I S DKT++++ K ++ H D V C FS + +
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKL-LEIKAHEDEVLCCAFSTD--DR 670
Query: 602 IIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTV--TVSPDGSLCASGGKDMXAMLWDL 775
I +C D+ VK+W+ +L + HS +N T S L A+G D LWDL
Sbjct: 671 FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDL 730
Query: 776 N 778
N
Sbjct: 731 N 731
Score = 54.4 bits (125), Expect = 4e-07
Identities = 51/204 (25%), Positives = 88/204 (43%), Gaps = 14/204 (6%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYAL--SGSWDKTLR 376
I + S DK + +W E + + HS ++ ++ ++ L +GS D L+
Sbjct: 672 IATCSVDKKVKIWNSMTGELVHTYDE-----HSEQVNCCHFTNSSHHLLLATGSSDCFLK 726
Query: 377 LWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN-TLAECKYTIQ---- 541
LWDL + HT V FS D++ + S S D T+KLW+ T A + +I
Sbjct: 727 LWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQF 786
Query: 542 ----DDGHSDW---VSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLN 700
+D D V C +S + A ++ + + +W+ + + GH +++
Sbjct: 787 FLNLEDPQEDMEVIVKCCSWSADGARIMVAA---KNKIFLWNTDSRSKVADCRGHLSWVH 843
Query: 701 TVTVSPDGSLCASGGKDMXAMLWD 772
V SPDGS + D LW+
Sbjct: 844 GVMFSPDGSSFLTSSDDQTIRLWE 867
Score = 51.2 bits (117), Expect = 4e-06
Identities = 44/179 (24%), Positives = 80/179 (44%), Gaps = 1/179 (0%)
Frame = +2
Query: 263 NYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLS 442
N I Q R + H + + ++D +S S D +++W+ K H + V
Sbjct: 949 NNRIFQSR-FQHKKTVWRIQFTADEKTLISSSDDAEIQVWNWQLDKCIF-LRGHQETVKD 1006
Query: 443 VAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGW 622
+ N +++S S D T+K+WN + K +SC +H S
Sbjct: 1007 FRL-LKNPRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSC---DISHDATKFSSTSA 1062
Query: 623 DRTVKVWHLTNCKLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
D+T K+W + L ++ L GH+G + S D +L A+G + +W++++G+ LH
Sbjct: 1063 DKTAKIWSF-DLLLPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLH 1120
Score = 43.2 bits (97), Expect = 0.001
Identities = 37/140 (26%), Positives = 58/140 (41%), Gaps = 8/140 (5%)
Frame = +2
Query: 134 RGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFIS 313
R T+ GH V +P ++ S S D TL +W T I K+ + +
Sbjct: 736 RNTMFGHTNSVNHCRFSPD-DKLLASCSADGTLKLWDATSANERKSINVKQFFLNLEDPQ 794
Query: 314 D---VVL-----SSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQ 469
+ V++ S+DG + + +K LW+ + H V V FS D
Sbjct: 795 EDMEVIVKCCSWSADGARIMVAAKNKIF-LWNTDSRSKVADCRGHLSWVHGVMFSPDGSS 853
Query: 470 IVSGSRDKTIKLWNTLAECK 529
++ S D+TI+LW T CK
Sbjct: 854 FLTSSDDQTIRLWETKKVCK 873
>AJ243005-1|CAB55581.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 87.0 bits (206), Expect = 7e-17
Identities = 50/160 (31%), Positives = 79/160 (49%), Gaps = 1/160 (0%)
Frame = +2
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H+ + S DG S DKTL+++ G+ + H +VL AFS D+R I
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 673
Query: 476 SGSRDKTIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
+ S DK +K+WN++ E +T D HS+ V+C F+ + + ++ + D +K+W L
Sbjct: 674 TCSVDKKVKIWNSMTGELVHTY--DEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN 731
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ + GH+ +N SPD L AS D LWD
Sbjct: 732 QKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWD 771
Score = 66.5 bits (155), Expect = 1e-10
Identities = 57/205 (27%), Positives = 96/205 (46%), Gaps = 10/205 (4%)
Frame = +2
Query: 161 WVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGN 340
W Q + K ++SSS D + VW D+ + L GH + D L +
Sbjct: 964 WHIQFTADEK---TLISSSDDAEIQVWNWQLDKCIF------LRGHQETVKDFRLLKNSR 1014
Query: 341 YALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN-TL 517
LS S+D T+++W++ G + F H VLS S D + S S DKT K+W+ L
Sbjct: 1015 L-LSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDL 1073
Query: 518 AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR-TVKVWHLTNCKL-----KINHL 679
+ ++ GH+ V C FS + +++ G D +++W+++N +L ++
Sbjct: 1074 LLPLHELR--GHNGCVRCSAFS---VDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEE 1128
Query: 680 G---HSGYLNTVTVSPDGSLCASGG 745
G H G++ + SPDG + S G
Sbjct: 1129 GAATHGGWVTDLCFSPDGKMLISAG 1153
Score = 58.0 bits (134), Expect = 4e-08
Identities = 39/158 (24%), Positives = 71/158 (44%), Gaps = 1/158 (0%)
Frame = +2
Query: 308 ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSR 487
+S LS Y G + + + +L + + H K V + F+ D + ++S S
Sbjct: 921 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 980
Query: 488 DKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKL 664
D I++WN L +C + GH + V R N ++S +D TVKVW++
Sbjct: 981 DAEIQVWNWQLDKCIFL---RGHQETVKDFRLLKNSR---LLSWSFDGTVKVWNIITGNK 1034
Query: 665 KINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLN 778
+ + + H G + + +S D + +S D A +W +
Sbjct: 1035 EKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFD 1072
Score = 57.6 bits (133), Expect = 5e-08
Identities = 39/121 (32%), Positives = 57/121 (47%), Gaps = 2/121 (1%)
Frame = +2
Query: 422 HTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANP 601
HT V FS D ++I S DKT++++ K ++ H D V C FS + +
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKL-LEIKAHEDEVLCCAFSTD--DR 670
Query: 602 IIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTV--TVSPDGSLCASGGKDMXAMLWDL 775
I +C D+ VK+W+ +L + HS +N T S L A+G D LWDL
Sbjct: 671 FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDL 730
Query: 776 N 778
N
Sbjct: 731 N 731
Score = 55.2 bits (127), Expect = 3e-07
Identities = 53/205 (25%), Positives = 91/205 (44%), Gaps = 15/205 (7%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYAL--SGSWDKTLR 376
I + S DK + +W E + + HS ++ ++ ++ L +GS D L+
Sbjct: 672 IATCSVDKKVKIWNSMTGELVHTYDE-----HSEQVNCCHFTNSSHHLLLATGSSDCFLK 726
Query: 377 LWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN-TLAECKYTIQ---- 541
LWDL + HT V FS D++ + S S D T+KLW+ T A + +I
Sbjct: 727 LWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQF 786
Query: 542 ----DDGHSDW---VSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL-GHSGYL 697
+D D V C +S + A ++ + + +W+ T+ + K+ GH ++
Sbjct: 787 FLNLEDPQGDMEVIVKCCSWSADGARIMVAA---KNKIFLWN-TDSRSKVTDCRGHLSWV 842
Query: 698 NTVTVSPDGSLCASGGKDMXAMLWD 772
+ V SPDGS + D LW+
Sbjct: 843 HGVMFSPDGSSFLTSSDDQTIRLWE 867
Score = 52.0 bits (119), Expect = 2e-06
Identities = 44/179 (24%), Positives = 80/179 (44%), Gaps = 1/179 (0%)
Frame = +2
Query: 263 NYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLS 442
N I Q R + H + + ++D +S S D +++W+ K H + V
Sbjct: 949 NNRIFQSR-FQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIF-LRGHQETVKD 1006
Query: 443 VAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGW 622
+ N +++S S D T+K+WN + K +SC +H S
Sbjct: 1007 FRL-LKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSC---DISHDATKFSSTSA 1062
Query: 623 DRTVKVWHLTNCKLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
D+T K+W + L ++ L GH+G + S D +L A+G + +W++++G+ LH
Sbjct: 1063 DKTAKIWSF-DLLLPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLH 1120
Score = 43.6 bits (98), Expect = 8e-04
Identities = 38/140 (27%), Positives = 55/140 (39%), Gaps = 8/140 (5%)
Frame = +2
Query: 134 RGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLY------- 292
R T+ GH V +P ++ S S D TL +W T I K+ +
Sbjct: 736 RNTMFGHTNSVNHCRFSPD-DKLLASCSADGTLKLWDATSANERKSINVKQFFLNLEDPQ 794
Query: 293 GHSHFISDVVL-SSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQ 469
G I S+DG + + +K LW+ + H V V FS D
Sbjct: 795 GDMEVIVKCCSWSADGARIMVAAKNKIF-LWNTDSRSKVTDCRGHLSWVHGVMFSPDGSS 853
Query: 470 IVSGSRDKTIKLWNTLAECK 529
++ S D+TI+LW T CK
Sbjct: 854 FLTSSDDQTIRLWETKKVCK 873
>AJ243004-1|CAB55580.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 87.0 bits (206), Expect = 7e-17
Identities = 50/160 (31%), Positives = 79/160 (49%), Gaps = 1/160 (0%)
Frame = +2
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H+ + S DG S DKTL+++ G+ + H +VL AFS D+R I
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 673
Query: 476 SGSRDKTIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
+ S DK +K+WN++ E +T D HS+ V+C F+ + + ++ + D +K+W L
Sbjct: 674 TCSVDKKVKIWNSMTGELVHTY--DEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN 731
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ + GH+ +N SPD L AS D LWD
Sbjct: 732 QKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWD 771
Score = 66.5 bits (155), Expect = 1e-10
Identities = 57/205 (27%), Positives = 96/205 (46%), Gaps = 10/205 (4%)
Frame = +2
Query: 161 WVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGN 340
W Q + K ++SSS D + VW D+ + L GH + D L +
Sbjct: 964 WHIQFTADEK---TLISSSDDAEIQVWNWQLDKCIF------LRGHQETVKDFRLLKNSR 1014
Query: 341 YALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN-TL 517
LS S+D T+++W++ G + F H VLS S D + S S DKT K+W+ L
Sbjct: 1015 L-LSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDL 1073
Query: 518 AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR-TVKVWHLTNCKL-----KINHL 679
+ ++ GH+ V C FS + +++ G D +++W+++N +L ++
Sbjct: 1074 LLPLHELR--GHNGCVRCSAFS---VDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEE 1128
Query: 680 G---HSGYLNTVTVSPDGSLCASGG 745
G H G++ + SPDG + S G
Sbjct: 1129 GAATHGGWVTDLCFSPDGKMLISAG 1153
Score = 58.0 bits (134), Expect = 4e-08
Identities = 39/158 (24%), Positives = 71/158 (44%), Gaps = 1/158 (0%)
Frame = +2
Query: 308 ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSR 487
+S LS Y G + + + +L + + H K V + F+ D + ++S S
Sbjct: 921 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 980
Query: 488 DKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKL 664
D I++WN L +C + GH + V R N ++S +D TVKVW++
Sbjct: 981 DAEIQVWNWQLDKCIFL---RGHQETVKDFRLLKNSR---LLSWSFDGTVKVWNIITGNK 1034
Query: 665 KINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLN 778
+ + + H G + + +S D + +S D A +W +
Sbjct: 1035 EKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFD 1072
Score = 57.6 bits (133), Expect = 5e-08
Identities = 39/121 (32%), Positives = 57/121 (47%), Gaps = 2/121 (1%)
Frame = +2
Query: 422 HTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANP 601
HT V FS D ++I S DKT++++ K ++ H D V C FS + +
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKL-LEIKAHEDEVLCCAFSTD--DR 670
Query: 602 IIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTV--TVSPDGSLCASGGKDMXAMLWDL 775
I +C D+ VK+W+ +L + HS +N T S L A+G D LWDL
Sbjct: 671 FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDL 730
Query: 776 N 778
N
Sbjct: 731 N 731
Score = 54.4 bits (125), Expect = 4e-07
Identities = 51/204 (25%), Positives = 88/204 (43%), Gaps = 14/204 (6%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYAL--SGSWDKTLR 376
I + S DK + +W E + + HS ++ ++ ++ L +GS D L+
Sbjct: 672 IATCSVDKKVKIWNSMTGELVHTYDE-----HSEQVNCCHFTNSSHHLLLATGSSDCFLK 726
Query: 377 LWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN-TLAECKYTIQ---- 541
LWDL + HT V FS D++ + S S D T+KLW+ T A + +I
Sbjct: 727 LWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQF 786
Query: 542 ----DDGHSDW---VSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLN 700
+D D V C +S + A ++ + + +W+ + + GH +++
Sbjct: 787 FLNLEDPQEDMEVIVKCCSWSADGARIMVAA---KNKIFLWNTDSRSKVADCRGHLSWVH 843
Query: 701 TVTVSPDGSLCASGGKDMXAMLWD 772
V SPDGS + D LW+
Sbjct: 844 GVMFSPDGSSFLTSSDDQTIRLWE 867
Score = 52.0 bits (119), Expect = 2e-06
Identities = 44/179 (24%), Positives = 80/179 (44%), Gaps = 1/179 (0%)
Frame = +2
Query: 263 NYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLS 442
N I Q R + H + + ++D +S S D +++W+ K H + V
Sbjct: 949 NNRIFQSR-FQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIF-LRGHQETVKD 1006
Query: 443 VAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGW 622
+ N +++S S D T+K+WN + K +SC +H S
Sbjct: 1007 FRL-LKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSC---DISHDATKFSSTSA 1062
Query: 623 DRTVKVWHLTNCKLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
D+T K+W + L ++ L GH+G + S D +L A+G + +W++++G+ LH
Sbjct: 1063 DKTAKIWSF-DLLLPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLH 1120
Score = 43.2 bits (97), Expect = 0.001
Identities = 37/140 (26%), Positives = 58/140 (41%), Gaps = 8/140 (5%)
Frame = +2
Query: 134 RGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFIS 313
R T+ GH V +P ++ S S D TL +W T I K+ + +
Sbjct: 736 RNTMFGHTNSVNHCRFSPD-DKLLASCSADGTLKLWDATSANERKSINVKQFFLNLEDPQ 794
Query: 314 D---VVL-----SSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQ 469
+ V++ S+DG + + +K LW+ + H V V FS D
Sbjct: 795 EDMEVIVKCCSWSADGARIMVAAKNKIF-LWNTDSRSKVADCRGHLSWVHGVMFSPDGSS 853
Query: 470 IVSGSRDKTIKLWNTLAECK 529
++ S D+TI+LW T CK
Sbjct: 854 FLTSSDDQTIRLWETKKVCK 873
>AJ243003-1|CAB55579.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 87.0 bits (206), Expect = 7e-17
Identities = 50/160 (31%), Positives = 79/160 (49%), Gaps = 1/160 (0%)
Frame = +2
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H+ + S DG S DKTL+++ G+ + H +VL AFS D+R I
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 673
Query: 476 SGSRDKTIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
+ S DK +K+WN++ E +T D HS+ V+C F+ + + ++ + D +K+W L
Sbjct: 674 TCSVDKKVKIWNSMTGELVHTY--DEHSEQVNCCHFANSSHHLLLATGSSDCFLKLWDLN 731
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ + GH+ +N SPD L AS D LWD
Sbjct: 732 QKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWD 771
Score = 66.5 bits (155), Expect = 1e-10
Identities = 57/205 (27%), Positives = 96/205 (46%), Gaps = 10/205 (4%)
Frame = +2
Query: 161 WVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGN 340
W Q + K ++SSS D + VW D+ + L GH + D L +
Sbjct: 964 WHIQFTADEK---TLISSSDDAEIQVWNWQLDKCIF------LRGHQETVKDFRLLKNSR 1014
Query: 341 YALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN-TL 517
LS S+D T+++W++ G + F H VLS S D + S S DKT K+W+ L
Sbjct: 1015 L-LSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDL 1073
Query: 518 AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR-TVKVWHLTNCKL-----KINHL 679
+ ++ GH+ V C FS + +++ G D +++W+++N +L ++
Sbjct: 1074 LLPLHELR--GHNGCVRCSAFS---VDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEE 1128
Query: 680 G---HSGYLNTVTVSPDGSLCASGG 745
G H G++ + SPDG + S G
Sbjct: 1129 GAATHGGWVTDLCFSPDGKMLISAG 1153
Score = 58.0 bits (134), Expect = 4e-08
Identities = 39/158 (24%), Positives = 71/158 (44%), Gaps = 1/158 (0%)
Frame = +2
Query: 308 ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSR 487
+S LS Y G + + + +L + + H K V + F+ D + ++S S
Sbjct: 921 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 980
Query: 488 DKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKL 664
D I++WN L +C + GH + V R N ++S +D TVKVW++
Sbjct: 981 DAEIQVWNWQLDKCIFL---RGHQETVKDFRLLKNSR---LLSWSFDGTVKVWNIITGNK 1034
Query: 665 KINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLN 778
+ + + H G + + +S D + +S D A +W +
Sbjct: 1035 EKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFD 1072
Score = 55.6 bits (128), Expect = 2e-07
Identities = 37/121 (30%), Positives = 56/121 (46%), Gaps = 2/121 (1%)
Frame = +2
Query: 422 HTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANP 601
HT V FS D ++I S DKT++++ K ++ H D V C FS + +
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKL-LEIKAHEDEVLCCAFSTD--DR 670
Query: 602 IIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS--LCASGGKDMXAMLWDL 775
I +C D+ VK+W+ +L + HS +N + L A+G D LWDL
Sbjct: 671 FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFANSSHHLLLATGSSDCFLKLWDL 730
Query: 776 N 778
N
Sbjct: 731 N 731
Score = 54.4 bits (125), Expect = 4e-07
Identities = 51/204 (25%), Positives = 88/204 (43%), Gaps = 14/204 (6%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYAL--SGSWDKTLR 376
I + S DK + +W E + + HS ++ ++ ++ L +GS D L+
Sbjct: 672 IATCSVDKKVKIWNSMTGELVHTYDE-----HSEQVNCCHFANSSHHLLLATGSSDCFLK 726
Query: 377 LWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN-TLAECKYTIQ---- 541
LWDL + HT V FS D++ + S S D T+KLW+ T A + +I
Sbjct: 727 LWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQF 786
Query: 542 ----DDGHSDW---VSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLN 700
+D D V C +S + A ++ + + +W+ + + GH +++
Sbjct: 787 FLNLEDPQEDMEVIVKCCSWSADGARIMVAA---KNKIFLWNTDSRSKVADCRGHLSWVH 843
Query: 701 TVTVSPDGSLCASGGKDMXAMLWD 772
V SPDGS + D LW+
Sbjct: 844 GVMFSPDGSSFLTSSDDQTIRLWE 867
Score = 52.0 bits (119), Expect = 2e-06
Identities = 44/179 (24%), Positives = 80/179 (44%), Gaps = 1/179 (0%)
Frame = +2
Query: 263 NYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLS 442
N I Q R + H + + ++D +S S D +++W+ K H + V
Sbjct: 949 NNRIFQSR-FQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIF-LRGHQETVKD 1006
Query: 443 VAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGW 622
+ N +++S S D T+K+WN + K +SC +H S
Sbjct: 1007 FRL-LKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSC---DISHDATKFSSTSA 1062
Query: 623 DRTVKVWHLTNCKLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
D+T K+W + L ++ L GH+G + S D +L A+G + +W++++G+ LH
Sbjct: 1063 DKTAKIWSF-DLLLPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLH 1120
Score = 43.2 bits (97), Expect = 0.001
Identities = 37/140 (26%), Positives = 58/140 (41%), Gaps = 8/140 (5%)
Frame = +2
Query: 134 RGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFIS 313
R T+ GH V +P ++ S S D TL +W T I K+ + +
Sbjct: 736 RNTMFGHTNSVNHCRFSPD-DKLLASCSADGTLKLWDATSANERKSINVKQFFLNLEDPQ 794
Query: 314 D---VVL-----SSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQ 469
+ V++ S+DG + + +K LW+ + H V V FS D
Sbjct: 795 EDMEVIVKCCSWSADGARIMVAAKNKIF-LWNTDSRSKVADCRGHLSWVHGVMFSPDGSS 853
Query: 470 IVSGSRDKTIKLWNTLAECK 529
++ S D+TI+LW T CK
Sbjct: 854 FLTSSDDQTIRLWETKKVCK 873
>AF411972-1|AAL06291.1| 627|Homo sapiens archipelago beta form
protein.
Length = 627
Score = 87.0 bits (206), Expect = 7e-17
Identities = 68/227 (29%), Positives = 107/227 (47%), Gaps = 3/227 (1%)
Frame = +2
Query: 122 TLKLRGTLRGHNG--WVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
T K TL GH G W +Q+ N +I+S S D+TL VW E + LYG
Sbjct: 330 TGKCLRTLVGHTGGVWSSQMRDN-----IIISGSTDRTLKVWNAETGECIH-----TLYG 379
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H+ + + L +SGS D TLR+WD+ G+ H V V + D R++V
Sbjct: 380 HTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQY--DGRRVV 435
Query: 476 SGSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
SG+ D +K+W+ E C +T+Q GH++ V ++F H +VS D +++VW +
Sbjct: 436 SGAYDFMVKVWDPETETCLHTLQ--GHTNRVYSLQFDGIH----VVSGSLDTSIRVWDVE 489
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
GH + + + ++ SG D +WD+ G+ L
Sbjct: 490 TGNCIHTLTGHQSLTSGMELK--DNILVSGNADSTVKIWDIKTGQCL 534
Score = 76.6 bits (180), Expect = 1e-13
Identities = 57/173 (32%), Positives = 77/173 (44%), Gaps = 1/173 (0%)
Frame = +2
Query: 281 KRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVD 460
K L GH + L GN +SGS D TL++W GK R HT V S D
Sbjct: 294 KVLKGHDDHVI-TCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMR-D 351
Query: 461 NRQIVSGSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVK 637
N I+SGS D+T+K+WN EC +T+ GH+ V C+ +VS D T++
Sbjct: 352 N-IIISGSTDRTLKVWNAETGECIHTLY--GHTSTVRCMHLHEKR----VVSGSRDATLR 404
Query: 638 VWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
VW + + +GH + V DG SG D +WD LH
Sbjct: 405 VWDIETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDPETETCLH 455
Score = 72.5 bits (170), Expect = 2e-12
Identities = 63/228 (27%), Positives = 102/228 (44%), Gaps = 2/228 (0%)
Frame = +2
Query: 116 SETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
+ET + TL GH V + + K ++S SRD TL VW + + + L G
Sbjct: 368 AETGECIHTLYGHTSTVRCMHLHEK---RVVSGSRDATLRVWDIETGQCLHV-----LMG 419
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H + V DG +SG++D +++WD + HT V S+ F D +V
Sbjct: 420 HVAAVRCV--QYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVV 475
Query: 476 SGSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
SGS D +I++W+ C +T+ GH S + N I+VS D TVK+W +
Sbjct: 476 SGSLDTSIRVWDVETGNCIHTL--TGHQSLTSGMELKDN----ILVSGNADSTVKIWDIK 529
Query: 653 NCKLKINHLGHSGYLNTVT-VSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ G + + + VT + + + + D LWDL G+ +
Sbjct: 530 TGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFI 577
Score = 65.7 bits (153), Expect = 2e-10
Identities = 44/162 (27%), Positives = 79/162 (48%), Gaps = 7/162 (4%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNR 466
L GH++ + L DG + +SGS D ++R+WD+ G H L+ + +
Sbjct: 457 LQGHTNRVYS--LQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS--LTSGMELKDN 512
Query: 467 QIVSGSRDKTIKLWN-TLAECKYTIQ-DDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKV 640
+VSG+ D T+K+W+ +C T+Q + H V+C++F+ N +++ D TVK+
Sbjct: 513 ILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKN----FVITSSDDGTVKL 568
Query: 641 WHLTNCKLKINHL-----GHSGYLNTVTVSPDGSLCASGGKD 751
W L + N + G G + + S +CA G ++
Sbjct: 569 WDLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRN 610
>AF411971-1|AAL06290.1| 707|Homo sapiens archipelago alpha form
protein.
Length = 707
Score = 87.0 bits (206), Expect = 7e-17
Identities = 68/227 (29%), Positives = 107/227 (47%), Gaps = 3/227 (1%)
Frame = +2
Query: 122 TLKLRGTLRGHNG--WVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
T K TL GH G W +Q+ N +I+S S D+TL VW E + LYG
Sbjct: 410 TGKCLRTLVGHTGGVWSSQMRDN-----IIISGSTDRTLKVWNAETGECIH-----TLYG 459
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H+ + + L +SGS D TLR+WD+ G+ H V V + D R++V
Sbjct: 460 HTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQY--DGRRVV 515
Query: 476 SGSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
SG+ D +K+W+ E C +T+Q GH++ V ++F H +VS D +++VW +
Sbjct: 516 SGAYDFMVKVWDPETETCLHTLQ--GHTNRVYSLQFDGIH----VVSGSLDTSIRVWDVE 569
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
GH + + + ++ SG D +WD+ G+ L
Sbjct: 570 TGNCIHTLTGHQSLTSGMELK--DNILVSGNADSTVKIWDIKTGQCL 614
Score = 76.6 bits (180), Expect = 1e-13
Identities = 57/173 (32%), Positives = 77/173 (44%), Gaps = 1/173 (0%)
Frame = +2
Query: 281 KRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVD 460
K L GH + L GN +SGS D TL++W GK R HT V S D
Sbjct: 374 KVLKGHDDHVI-TCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMR-D 431
Query: 461 NRQIVSGSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVK 637
N I+SGS D+T+K+WN EC +T+ GH+ V C+ +VS D T++
Sbjct: 432 N-IIISGSTDRTLKVWNAETGECIHTLY--GHTSTVRCMHLHEKR----VVSGSRDATLR 484
Query: 638 VWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
VW + + +GH + V DG SG D +WD LH
Sbjct: 485 VWDIETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDPETETCLH 535
Score = 72.5 bits (170), Expect = 2e-12
Identities = 63/228 (27%), Positives = 102/228 (44%), Gaps = 2/228 (0%)
Frame = +2
Query: 116 SETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
+ET + TL GH V + + K ++S SRD TL VW + + + L G
Sbjct: 448 AETGECIHTLYGHTSTVRCMHLHEK---RVVSGSRDATLRVWDIETGQCLHV-----LMG 499
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H + V DG +SG++D +++WD + HT V S+ F D +V
Sbjct: 500 HVAAVRCV--QYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVV 555
Query: 476 SGSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
SGS D +I++W+ C +T+ GH S + N I+VS D TVK+W +
Sbjct: 556 SGSLDTSIRVWDVETGNCIHTL--TGHQSLTSGMELKDN----ILVSGNADSTVKIWDIK 609
Query: 653 NCKLKINHLGHSGYLNTVT-VSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ G + + + VT + + + + D LWDL G+ +
Sbjct: 610 TGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFI 657
Score = 65.7 bits (153), Expect = 2e-10
Identities = 44/162 (27%), Positives = 79/162 (48%), Gaps = 7/162 (4%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNR 466
L GH++ + L DG + +SGS D ++R+WD+ G H L+ + +
Sbjct: 537 LQGHTNRVYS--LQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS--LTSGMELKDN 592
Query: 467 QIVSGSRDKTIKLWN-TLAECKYTIQ-DDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKV 640
+VSG+ D T+K+W+ +C T+Q + H V+C++F+ N +++ D TVK+
Sbjct: 593 ILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKN----FVITSSDDGTVKL 648
Query: 641 WHLTNCKLKINHL-----GHSGYLNTVTVSPDGSLCASGGKD 751
W L + N + G G + + S +CA G ++
Sbjct: 649 WDLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRN 690
>AF383178-1|AAK60269.1| 561|Homo sapiens F-box protein FBX30
protein.
Length = 561
Score = 87.0 bits (206), Expect = 7e-17
Identities = 68/227 (29%), Positives = 107/227 (47%), Gaps = 3/227 (1%)
Frame = +2
Query: 122 TLKLRGTLRGHNG--WVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
T K TL GH G W +Q+ N +I+S S D+TL VW E + LYG
Sbjct: 264 TGKCLRTLVGHTGGVWSSQMRDN-----IIISGSTDRTLKVWNAETGECIH-----TLYG 313
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H+ + + L +SGS D TLR+WD+ G+ H V V + D R++V
Sbjct: 314 HTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQY--DGRRVV 369
Query: 476 SGSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
SG+ D +K+W+ E C +T+Q GH++ V ++F H +VS D +++VW +
Sbjct: 370 SGAYDFMVKVWDPETETCLHTLQ--GHTNRVYSLQFDGIH----VVSGSLDTSIRVWDVE 423
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
GH + + + ++ SG D +WD+ G+ L
Sbjct: 424 TGNCIHTLTGHQSLTSGMELK--DNILVSGNADSTVKIWDIKTGQCL 468
Score = 76.6 bits (180), Expect = 1e-13
Identities = 57/173 (32%), Positives = 77/173 (44%), Gaps = 1/173 (0%)
Frame = +2
Query: 281 KRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVD 460
K L GH + L GN +SGS D TL++W GK R HT V S D
Sbjct: 228 KVLKGHDDHVI-TCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMR-D 285
Query: 461 NRQIVSGSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVK 637
N I+SGS D+T+K+WN EC +T+ GH+ V C+ +VS D T++
Sbjct: 286 N-IIISGSTDRTLKVWNAETGECIHTLY--GHTSTVRCMHLHEKR----VVSGSRDATLR 338
Query: 638 VWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
VW + + +GH + V DG SG D +WD LH
Sbjct: 339 VWDIETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDPETETCLH 389
Score = 72.5 bits (170), Expect = 2e-12
Identities = 63/228 (27%), Positives = 102/228 (44%), Gaps = 2/228 (0%)
Frame = +2
Query: 116 SETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
+ET + TL GH V + + K ++S SRD TL VW + + + L G
Sbjct: 302 AETGECIHTLYGHTSTVRCMHLHEK---RVVSGSRDATLRVWDIETGQCLHV-----LMG 353
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H + V DG +SG++D +++WD + HT V S+ F D +V
Sbjct: 354 HVAAVRCV--QYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVV 409
Query: 476 SGSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
SGS D +I++W+ C +T+ GH S + N I+VS D TVK+W +
Sbjct: 410 SGSLDTSIRVWDVETGNCIHTL--TGHQSLTSGMELKDN----ILVSGNADSTVKIWDIK 463
Query: 653 NCKLKINHLGHSGYLNTVT-VSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ G + + + VT + + + + D LWDL G+ +
Sbjct: 464 TGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFI 511
Score = 65.7 bits (153), Expect = 2e-10
Identities = 44/162 (27%), Positives = 79/162 (48%), Gaps = 7/162 (4%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNR 466
L GH++ + L DG + +SGS D ++R+WD+ G H L+ + +
Sbjct: 391 LQGHTNRVYS--LQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS--LTSGMELKDN 446
Query: 467 QIVSGSRDKTIKLWN-TLAECKYTIQ-DDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKV 640
+VSG+ D T+K+W+ +C T+Q + H V+C++F+ N +++ D TVK+
Sbjct: 447 ILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKN----FVITSSDDGTVKL 502
Query: 641 WHLTNCKLKINHL-----GHSGYLNTVTVSPDGSLCASGGKD 751
W L + N + G G + + S +CA G ++
Sbjct: 503 WDLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRN 544
>AF149794-1|AAD34016.1| 1248|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1248
Score = 87.0 bits (206), Expect = 7e-17
Identities = 50/160 (31%), Positives = 79/160 (49%), Gaps = 1/160 (0%)
Frame = +2
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H+ + S DG S DKTL+++ G+ + H +VL AFS D+R I
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 673
Query: 476 SGSRDKTIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
+ S DK +K+WN++ E +T D HS+ V+C F+ + + ++ + D +K+W L
Sbjct: 674 TCSVDKKVKIWNSMTGELVHTY--DEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN 731
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ + GH+ +N SPD L AS D LWD
Sbjct: 732 QKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWD 771
Score = 66.5 bits (155), Expect = 1e-10
Identities = 57/205 (27%), Positives = 96/205 (46%), Gaps = 10/205 (4%)
Frame = +2
Query: 161 WVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGN 340
W Q + K ++SSS D + VW D+ + L GH + D L +
Sbjct: 1007 WHIQFTADEK---TLISSSDDAEIQVWNWQLDKCIF------LRGHQETVKDFRLLKNSR 1057
Query: 341 YALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN-TL 517
LS S+D T+++W++ G + F H VLS S D + S S DKT K+W+ L
Sbjct: 1058 L-LSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDL 1116
Query: 518 AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR-TVKVWHLTNCKL-----KINHL 679
+ ++ GH+ V C FS + +++ G D +++W+++N +L ++
Sbjct: 1117 LLPLHELR--GHNGCVRCSAFS---VDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEE 1171
Query: 680 G---HSGYLNTVTVSPDGSLCASGG 745
G H G++ + SPDG + S G
Sbjct: 1172 GAATHGGWVTDLCFSPDGKMLISAG 1196
Score = 58.0 bits (134), Expect = 4e-08
Identities = 39/158 (24%), Positives = 71/158 (44%), Gaps = 1/158 (0%)
Frame = +2
Query: 308 ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSR 487
+S LS Y G + + + +L + + H K V + F+ D + ++S S
Sbjct: 964 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 1023
Query: 488 DKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKL 664
D I++WN L +C + GH + V R N ++S +D TVKVW++
Sbjct: 1024 DAEIQVWNWQLDKCIFL---RGHQETVKDFRLLKNSR---LLSWSFDGTVKVWNIITGNK 1077
Query: 665 KINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLN 778
+ + + H G + + +S D + +S D A +W +
Sbjct: 1078 EKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFD 1115
Score = 57.6 bits (133), Expect = 5e-08
Identities = 39/121 (32%), Positives = 57/121 (47%), Gaps = 2/121 (1%)
Frame = +2
Query: 422 HTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANP 601
HT V FS D ++I S DKT++++ K ++ H D V C FS + +
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKL-LEIKAHEDEVLCCAFSTD--DR 670
Query: 602 IIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTV--TVSPDGSLCASGGKDMXAMLWDL 775
I +C D+ VK+W+ +L + HS +N T S L A+G D LWDL
Sbjct: 671 FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDL 730
Query: 776 N 778
N
Sbjct: 731 N 731
Score = 53.2 bits (122), Expect = 1e-06
Identities = 51/212 (24%), Positives = 90/212 (42%), Gaps = 14/212 (6%)
Frame = +2
Query: 179 TNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGS 358
TN + ++ + S D L +W L + E + ++GH++ ++ S D S S
Sbjct: 708 TNSSHHLLLATGSSDCFLKLWDLNQKEC-----RNTMFGHTNSVNHCRFSPDDKLLASCS 762
Query: 359 WDKTLRLWDLAAGKTTR---------RFEDHTKD----VLSVAFSVDNRQIVSGSRDKTI 499
D TL+LWD + + ED +D V ++S D +I+ +++K I
Sbjct: 763 ADGTLKLWDATSANERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNK-I 821
Query: 500 KLWNTLAECKYTIQDDGHSDWVSCVRFSP-NHANPIIVSCGWDRTVKVWHLTNCKLKINH 676
L++ GH + FSP NH + +S V++W+ + +
Sbjct: 822 FLFDIHTSGLLGEIHTGHHSTIQYCDFSPQNHLAVVALS---QYCVELWNTDSRSKVADC 878
Query: 677 LGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
GH +++ V SPDGS + D LW+
Sbjct: 879 RGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWE 910
Score = 52.0 bits (119), Expect = 2e-06
Identities = 44/179 (24%), Positives = 80/179 (44%), Gaps = 1/179 (0%)
Frame = +2
Query: 263 NYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLS 442
N I Q R + H + + ++D +S S D +++W+ K H + V
Sbjct: 992 NNRIFQSR-FQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIF-LRGHQETVKD 1049
Query: 443 VAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGW 622
+ N +++S S D T+K+WN + K +SC +H S
Sbjct: 1050 FRL-LKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSC---DISHDATKFSSTSA 1105
Query: 623 DRTVKVWHLTNCKLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
D+T K+W + L ++ L GH+G + S D +L A+G + +W++++G+ LH
Sbjct: 1106 DKTAKIWSF-DLLLPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLH 1163
Score = 37.1 bits (82), Expect = 0.073
Identities = 22/79 (27%), Positives = 31/79 (39%)
Frame = +2
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI 472
GH I S + A+ + LW+ + H V V FS D
Sbjct: 838 GHHSTIQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSF 897
Query: 473 VSGSRDKTIKLWNTLAECK 529
++ S D+TI+LW T CK
Sbjct: 898 LTSSDDQTIRLWETKKVCK 916
>AF134397-1|AAD38344.1| 1237|Homo sapiens apoptotic protease
activating factor-1 long isoform APAF-1L protein.
Length = 1237
Score = 87.0 bits (206), Expect = 7e-17
Identities = 50/160 (31%), Positives = 79/160 (49%), Gaps = 1/160 (0%)
Frame = +2
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H+ + S DG S DKTL+++ G+ + H +VL AFS D+R I
Sbjct: 603 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 662
Query: 476 SGSRDKTIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
+ S DK +K+WN++ E +T D HS+ V+C F+ + + ++ + D +K+W L
Sbjct: 663 TCSVDKKVKIWNSMTGELVHTY--DEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN 720
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ + GH+ +N SPD L AS D LWD
Sbjct: 721 QKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWD 760
Score = 66.5 bits (155), Expect = 1e-10
Identities = 57/205 (27%), Positives = 96/205 (46%), Gaps = 10/205 (4%)
Frame = +2
Query: 161 WVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGN 340
W Q + K ++SSS D + VW D+ + L GH + D L +
Sbjct: 996 WHIQFTADEK---TLISSSDDAEIQVWNWQLDKCIF------LRGHQETVKDFRLLKNSR 1046
Query: 341 YALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN-TL 517
LS S+D T+++W++ G + F H VLS S D + S S DKT K+W+ L
Sbjct: 1047 L-LSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDL 1105
Query: 518 AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR-TVKVWHLTNCKL-----KINHL 679
+ ++ GH+ V C FS + +++ G D +++W+++N +L ++
Sbjct: 1106 LLPLHELR--GHNGCVRCSAFS---VDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEE 1160
Query: 680 G---HSGYLNTVTVSPDGSLCASGG 745
G H G++ + SPDG + S G
Sbjct: 1161 GAATHGGWVTDLCFSPDGKMLISAG 1185
Score = 58.0 bits (134), Expect = 4e-08
Identities = 39/158 (24%), Positives = 71/158 (44%), Gaps = 1/158 (0%)
Frame = +2
Query: 308 ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSR 487
+S LS Y G + + + +L + + H K V + F+ D + ++S S
Sbjct: 953 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 1012
Query: 488 DKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKL 664
D I++WN L +C + GH + V R N ++S +D TVKVW++
Sbjct: 1013 DAEIQVWNWQLDKCIFL---RGHQETVKDFRLLKNSR---LLSWSFDGTVKVWNIITGNK 1066
Query: 665 KINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLN 778
+ + + H G + + +S D + +S D A +W +
Sbjct: 1067 EKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFD 1104
Score = 57.6 bits (133), Expect = 5e-08
Identities = 39/121 (32%), Positives = 57/121 (47%), Gaps = 2/121 (1%)
Frame = +2
Query: 422 HTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANP 601
HT V FS D ++I S DKT++++ K ++ H D V C FS + +
Sbjct: 603 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKL-LEIKAHEDEVLCCAFSTD--DR 659
Query: 602 IIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTV--TVSPDGSLCASGGKDMXAMLWDL 775
I +C D+ VK+W+ +L + HS +N T S L A+G D LWDL
Sbjct: 660 FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDL 719
Query: 776 N 778
N
Sbjct: 720 N 720
Score = 53.2 bits (122), Expect = 1e-06
Identities = 51/212 (24%), Positives = 90/212 (42%), Gaps = 14/212 (6%)
Frame = +2
Query: 179 TNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGS 358
TN + ++ + S D L +W L + E + ++GH++ ++ S D S S
Sbjct: 697 TNSSHHLLLATGSSDCFLKLWDLNQKEC-----RNTMFGHTNSVNHCRFSPDDKLLASCS 751
Query: 359 WDKTLRLWDLAAGKTTR---------RFEDHTKD----VLSVAFSVDNRQIVSGSRDKTI 499
D TL+LWD + + ED +D V ++S D +I+ +++K I
Sbjct: 752 ADGTLKLWDATSANERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNK-I 810
Query: 500 KLWNTLAECKYTIQDDGHSDWVSCVRFSP-NHANPIIVSCGWDRTVKVWHLTNCKLKINH 676
L++ GH + FSP NH + +S V++W+ + +
Sbjct: 811 FLFDIHTSGLLGEIHTGHHSTIQYCDFSPQNHLAVVALS---QYCVELWNTDSRSKVADC 867
Query: 677 LGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
GH +++ V SPDGS + D LW+
Sbjct: 868 RGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWE 899
Score = 52.0 bits (119), Expect = 2e-06
Identities = 44/179 (24%), Positives = 80/179 (44%), Gaps = 1/179 (0%)
Frame = +2
Query: 263 NYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLS 442
N I Q R + H + + ++D +S S D +++W+ K H + V
Sbjct: 981 NNRIFQSR-FQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIF-LRGHQETVKD 1038
Query: 443 VAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGW 622
+ N +++S S D T+K+WN + K +SC +H S
Sbjct: 1039 FRL-LKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSC---DISHDATKFSSTSA 1094
Query: 623 DRTVKVWHLTNCKLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
D+T K+W + L ++ L GH+G + S D +L A+G + +W++++G+ LH
Sbjct: 1095 DKTAKIWSF-DLLLPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLH 1152
Score = 37.1 bits (82), Expect = 0.073
Identities = 22/79 (27%), Positives = 31/79 (39%)
Frame = +2
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI 472
GH I S + A+ + LW+ + H V V FS D
Sbjct: 827 GHHSTIQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSF 886
Query: 473 VSGSRDKTIKLWNTLAECK 529
++ S D+TI+LW T CK
Sbjct: 887 LTSSDDQTIRLWETKKVCK 905
>AF013263-1|AAC51678.1| 1194|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1194
Score = 87.0 bits (206), Expect = 7e-17
Identities = 50/160 (31%), Positives = 79/160 (49%), Gaps = 1/160 (0%)
Frame = +2
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H+ + S DG S DKTL+++ G+ + H +VL AFS D+R I
Sbjct: 603 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 662
Query: 476 SGSRDKTIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
+ S DK +K+WN++ E +T D HS+ V+C F+ + + ++ + D +K+W L
Sbjct: 663 TCSVDKKVKIWNSMTGELVHTY--DEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN 720
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ + GH+ +N SPD L AS D LWD
Sbjct: 721 QKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWD 760
Score = 66.5 bits (155), Expect = 1e-10
Identities = 57/205 (27%), Positives = 96/205 (46%), Gaps = 10/205 (4%)
Frame = +2
Query: 161 WVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGN 340
W Q + K ++SSS D + VW D+ + L GH + D L +
Sbjct: 953 WHIQFTADEK---TLISSSDDAEIQVWNWQLDKCIF------LRGHQETVKDFRLLKNSR 1003
Query: 341 YALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN-TL 517
LS S+D T+++W++ G + F H VLS S D + S S DKT K+W+ L
Sbjct: 1004 L-LSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDL 1062
Query: 518 AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR-TVKVWHLTNCKL-----KINHL 679
+ ++ GH+ V C FS + +++ G D +++W+++N +L ++
Sbjct: 1063 LLPLHELR--GHNGCVRCSAFS---VDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEE 1117
Query: 680 G---HSGYLNTVTVSPDGSLCASGG 745
G H G++ + SPDG + S G
Sbjct: 1118 GAATHGGWVTDLCFSPDGKMLISAG 1142
Score = 58.0 bits (134), Expect = 4e-08
Identities = 39/158 (24%), Positives = 71/158 (44%), Gaps = 1/158 (0%)
Frame = +2
Query: 308 ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSR 487
+S LS Y G + + + +L + + H K V + F+ D + ++S S
Sbjct: 910 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 969
Query: 488 DKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKL 664
D I++WN L +C + GH + V R N ++S +D TVKVW++
Sbjct: 970 DAEIQVWNWQLDKCIFL---RGHQETVKDFRLLKNSR---LLSWSFDGTVKVWNIITGNK 1023
Query: 665 KINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLN 778
+ + + H G + + +S D + +S D A +W +
Sbjct: 1024 EKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFD 1061
Score = 57.6 bits (133), Expect = 5e-08
Identities = 39/121 (32%), Positives = 57/121 (47%), Gaps = 2/121 (1%)
Frame = +2
Query: 422 HTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANP 601
HT V FS D ++I S DKT++++ K ++ H D V C FS + +
Sbjct: 603 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKL-LEIKAHEDEVLCCAFSTD--DR 659
Query: 602 IIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTV--TVSPDGSLCASGGKDMXAMLWDL 775
I +C D+ VK+W+ +L + HS +N T S L A+G D LWDL
Sbjct: 660 FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDL 719
Query: 776 N 778
N
Sbjct: 720 N 720
Score = 54.4 bits (125), Expect = 4e-07
Identities = 51/204 (25%), Positives = 88/204 (43%), Gaps = 14/204 (6%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYAL--SGSWDKTLR 376
I + S DK + +W E + + HS ++ ++ ++ L +GS D L+
Sbjct: 661 IATCSVDKKVKIWNSMTGELVHTYDE-----HSEQVNCCHFTNSSHHLLLATGSSDCFLK 715
Query: 377 LWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN-TLAECKYTIQ---- 541
LWDL + HT V FS D++ + S S D T+KLW+ T A + +I
Sbjct: 716 LWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQF 775
Query: 542 ----DDGHSDW---VSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLN 700
+D D V C +S + A ++ + + +W+ + + GH +++
Sbjct: 776 FLNLEDPQEDMEVIVKCCSWSADGARIMVAA---KNKIFLWNTDSRSKVADCRGHLSWVH 832
Query: 701 TVTVSPDGSLCASGGKDMXAMLWD 772
V SPDGS + D LW+
Sbjct: 833 GVMFSPDGSSFLTSSDDQTIRLWE 856
Score = 52.0 bits (119), Expect = 2e-06
Identities = 44/179 (24%), Positives = 80/179 (44%), Gaps = 1/179 (0%)
Frame = +2
Query: 263 NYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLS 442
N I Q R + H + + ++D +S S D +++W+ K H + V
Sbjct: 938 NNRIFQSR-FQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIF-LRGHQETVKD 995
Query: 443 VAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGW 622
+ N +++S S D T+K+WN + K +SC +H S
Sbjct: 996 FRL-LKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSC---DISHDATKFSSTSA 1051
Query: 623 DRTVKVWHLTNCKLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
D+T K+W + L ++ L GH+G + S D +L A+G + +W++++G+ LH
Sbjct: 1052 DKTAKIWSF-DLLLPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLH 1109
Score = 43.2 bits (97), Expect = 0.001
Identities = 37/140 (26%), Positives = 58/140 (41%), Gaps = 8/140 (5%)
Frame = +2
Query: 134 RGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFIS 313
R T+ GH V +P ++ S S D TL +W T I K+ + +
Sbjct: 725 RNTMFGHTNSVNHCRFSPD-DKLLASCSADGTLKLWDATSANERKSINVKQFFLNLEDPQ 783
Query: 314 D---VVL-----SSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQ 469
+ V++ S+DG + + +K LW+ + H V V FS D
Sbjct: 784 EDMEVIVKCCSWSADGARIMVAAKNKIF-LWNTDSRSKVADCRGHLSWVHGVMFSPDGSS 842
Query: 470 IVSGSRDKTIKLWNTLAECK 529
++ S D+TI+LW T CK
Sbjct: 843 FLTSSDDQTIRLWETKKVCK 862
>AB209725-1|BAD92962.1| 624|Homo sapiens F-box protein FBW7 isoform
2 variant protein.
Length = 624
Score = 87.0 bits (206), Expect = 7e-17
Identities = 68/227 (29%), Positives = 107/227 (47%), Gaps = 3/227 (1%)
Frame = +2
Query: 122 TLKLRGTLRGHNG--WVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
T K TL GH G W +Q+ N +I+S S D+TL VW E + LYG
Sbjct: 327 TGKCLRTLVGHTGGVWSSQMRDN-----IIISGSTDRTLKVWNAETGECIH-----TLYG 376
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H+ + + L +SGS D TLR+WD+ G+ H V V + D R++V
Sbjct: 377 HTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQY--DGRRVV 432
Query: 476 SGSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
SG+ D +K+W+ E C +T+Q GH++ V ++F H +VS D +++VW +
Sbjct: 433 SGAYDFMVKVWDPETETCLHTLQ--GHTNRVYSLQFDGIH----VVSGSLDTSIRVWDVE 486
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
GH + + + ++ SG D +WD+ G+ L
Sbjct: 487 TGNCIHTLTGHQSLTSGMELK--DNILVSGNADSTVKIWDIKTGQCL 531
Score = 76.6 bits (180), Expect = 1e-13
Identities = 57/173 (32%), Positives = 77/173 (44%), Gaps = 1/173 (0%)
Frame = +2
Query: 281 KRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVD 460
K L GH + L GN +SGS D TL++W GK R HT V S D
Sbjct: 291 KVLKGHDDHVI-TCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMR-D 348
Query: 461 NRQIVSGSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVK 637
N I+SGS D+T+K+WN EC +T+ GH+ V C+ +VS D T++
Sbjct: 349 N-IIISGSTDRTLKVWNAETGECIHTLY--GHTSTVRCMHLHEKR----VVSGSRDATLR 401
Query: 638 VWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
VW + + +GH + V DG SG D +WD LH
Sbjct: 402 VWDIETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDPETETCLH 452
Score = 72.5 bits (170), Expect = 2e-12
Identities = 63/228 (27%), Positives = 102/228 (44%), Gaps = 2/228 (0%)
Frame = +2
Query: 116 SETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
+ET + TL GH V + + K ++S SRD TL VW + + + L G
Sbjct: 365 AETGECIHTLYGHTSTVRCMHLHEK---RVVSGSRDATLRVWDIETGQCLHV-----LMG 416
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H + V DG +SG++D +++WD + HT V S+ F D +V
Sbjct: 417 HVAAVRCV--QYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVV 472
Query: 476 SGSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
SGS D +I++W+ C +T+ GH S + N I+VS D TVK+W +
Sbjct: 473 SGSLDTSIRVWDVETGNCIHTL--TGHQSLTSGMELKDN----ILVSGNADSTVKIWDIK 526
Query: 653 NCKLKINHLGHSGYLNTVT-VSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ G + + + VT + + + + D LWDL G+ +
Sbjct: 527 TGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFI 574
Score = 65.7 bits (153), Expect = 2e-10
Identities = 44/162 (27%), Positives = 79/162 (48%), Gaps = 7/162 (4%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNR 466
L GH++ + L DG + +SGS D ++R+WD+ G H L+ + +
Sbjct: 454 LQGHTNRVYS--LQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS--LTSGMELKDN 509
Query: 467 QIVSGSRDKTIKLWN-TLAECKYTIQ-DDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKV 640
+VSG+ D T+K+W+ +C T+Q + H V+C++F+ N +++ D TVK+
Sbjct: 510 ILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKN----FVITSSDDGTVKL 565
Query: 641 WHLTNCKLKINHL-----GHSGYLNTVTVSPDGSLCASGGKD 751
W L + N + G G + + S +CA G ++
Sbjct: 566 WDLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRN 607
>AB007873-1|BAA24843.2| 1237|Homo sapiens KIAA0413 protein.
Length = 1237
Score = 87.0 bits (206), Expect = 7e-17
Identities = 50/160 (31%), Positives = 79/160 (49%), Gaps = 1/160 (0%)
Frame = +2
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H+ + S DG S DKTL+++ G+ + H +VL AFS D+R I
Sbjct: 603 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 662
Query: 476 SGSRDKTIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
+ S DK +K+WN++ E +T D HS+ V+C F+ + + ++ + D +K+W L
Sbjct: 663 TCSVDKKVKIWNSMTGELVHTY--DEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN 720
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ + GH+ +N SPD L AS D LWD
Sbjct: 721 QKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWD 760
Score = 66.5 bits (155), Expect = 1e-10
Identities = 57/205 (27%), Positives = 96/205 (46%), Gaps = 10/205 (4%)
Frame = +2
Query: 161 WVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGN 340
W Q + K ++SSS D + VW D+ + L GH + D L +
Sbjct: 996 WHIQFTADEK---TLISSSDDAEIQVWNWQLDKCIF------LRGHQETVKDFRLLKNSR 1046
Query: 341 YALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN-TL 517
LS S+D T+++W++ G + F H VLS S D + S S DKT K+W+ L
Sbjct: 1047 L-LSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDL 1105
Query: 518 AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR-TVKVWHLTNCKL-----KINHL 679
+ ++ GH+ V C FS + +++ G D +++W+++N +L ++
Sbjct: 1106 LLPLHELR--GHNGCVRCSAFS---VDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEE 1160
Query: 680 G---HSGYLNTVTVSPDGSLCASGG 745
G H G++ + SPDG + S G
Sbjct: 1161 GAATHGGWVTDLCFSPDGKMLISAG 1185
Score = 58.0 bits (134), Expect = 4e-08
Identities = 39/158 (24%), Positives = 71/158 (44%), Gaps = 1/158 (0%)
Frame = +2
Query: 308 ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSR 487
+S LS Y G + + + +L + + H K V + F+ D + ++S S
Sbjct: 953 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 1012
Query: 488 DKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKL 664
D I++WN L +C + GH + V R N ++S +D TVKVW++
Sbjct: 1013 DAEIQVWNWQLDKCIFL---RGHQETVKDFRLLKNSR---LLSWSFDGTVKVWNIITGNK 1066
Query: 665 KINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLN 778
+ + + H G + + +S D + +S D A +W +
Sbjct: 1067 EKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFD 1104
Score = 57.6 bits (133), Expect = 5e-08
Identities = 39/121 (32%), Positives = 57/121 (47%), Gaps = 2/121 (1%)
Frame = +2
Query: 422 HTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANP 601
HT V FS D ++I S DKT++++ K ++ H D V C FS + +
Sbjct: 603 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKL-LEIKAHEDEVLCCAFSTD--DR 659
Query: 602 IIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTV--TVSPDGSLCASGGKDMXAMLWDL 775
I +C D+ VK+W+ +L + HS +N T S L A+G D LWDL
Sbjct: 660 FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDL 719
Query: 776 N 778
N
Sbjct: 720 N 720
Score = 53.2 bits (122), Expect = 1e-06
Identities = 51/212 (24%), Positives = 90/212 (42%), Gaps = 14/212 (6%)
Frame = +2
Query: 179 TNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGS 358
TN + ++ + S D L +W L + E + ++GH++ ++ S D S S
Sbjct: 697 TNSSHHLLLATGSSDCFLKLWDLNQKEC-----RNTMFGHTNSVNHCRFSPDDKLLASCS 751
Query: 359 WDKTLRLWDLAAGKTTR---------RFEDHTKD----VLSVAFSVDNRQIVSGSRDKTI 499
D TL+LWD + + ED +D V ++S D +I+ +++K I
Sbjct: 752 ADGTLKLWDATSANERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNK-I 810
Query: 500 KLWNTLAECKYTIQDDGHSDWVSCVRFSP-NHANPIIVSCGWDRTVKVWHLTNCKLKINH 676
L++ GH + FSP NH + +S V++W+ + +
Sbjct: 811 FLFDIHTSGLLGEIHTGHHSTIQYCDFSPQNHLAVVALS---QYCVELWNTDSRSKVADC 867
Query: 677 LGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
GH +++ V SPDGS + D LW+
Sbjct: 868 RGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWE 899
Score = 52.0 bits (119), Expect = 2e-06
Identities = 44/179 (24%), Positives = 80/179 (44%), Gaps = 1/179 (0%)
Frame = +2
Query: 263 NYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLS 442
N I Q R + H + + ++D +S S D +++W+ K H + V
Sbjct: 981 NNRIFQSR-FQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIF-LRGHQETVKD 1038
Query: 443 VAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGW 622
+ N +++S S D T+K+WN + K +SC +H S
Sbjct: 1039 FRL-LKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSC---DISHDATKFSSTSA 1094
Query: 623 DRTVKVWHLTNCKLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
D+T K+W + L ++ L GH+G + S D +L A+G + +W++++G+ LH
Sbjct: 1095 DKTAKIWSF-DLLLPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLH 1152
Score = 37.1 bits (82), Expect = 0.073
Identities = 22/79 (27%), Positives = 31/79 (39%)
Frame = +2
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI 472
GH I S + A+ + LW+ + H V V FS D
Sbjct: 827 GHHSTIQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSF 886
Query: 473 VSGSRDKTIKLWNTLAECK 529
++ S D+TI+LW T CK
Sbjct: 887 LTSSDDQTIRLWETKKVCK 905
>AJ243011-1|CAB55587.1| 1205|Homo sapiens protease activating factor-1
protein.
Length = 1205
Score = 86.6 bits (205), Expect = 9e-17
Identities = 50/160 (31%), Positives = 79/160 (49%), Gaps = 1/160 (0%)
Frame = +2
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H+ + S DG S DKTL+++ G+ + H +VL AFS D+R I
Sbjct: 614 HTDAVYRACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 673
Query: 476 SGSRDKTIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
+ S DK +K+WN++ E +T D HS+ V+C F+ + + ++ + D +K+W L
Sbjct: 674 TCSVDKKVKIWNSMTGELVHTY--DEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN 731
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ + GH+ +N SPD L AS D LWD
Sbjct: 732 QKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWD 771
Score = 66.5 bits (155), Expect = 1e-10
Identities = 57/205 (27%), Positives = 96/205 (46%), Gaps = 10/205 (4%)
Frame = +2
Query: 161 WVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGN 340
W Q + K ++SSS D + VW D+ + L GH + D L +
Sbjct: 964 WHIQFTADEK---TLISSSDDAEIQVWNWQLDKCIF------LRGHQETVKDFRLLKNSR 1014
Query: 341 YALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN-TL 517
LS S+D T+++W++ G + F H VLS S D + S S DKT K+W+ L
Sbjct: 1015 L-LSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDL 1073
Query: 518 AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR-TVKVWHLTNCKL-----KINHL 679
+ ++ GH+ V C FS + +++ G D +++W+++N +L ++
Sbjct: 1074 LLPLHELR--GHNGCVRCSAFS---VDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEE 1128
Query: 680 G---HSGYLNTVTVSPDGSLCASGG 745
G H G++ + SPDG + S G
Sbjct: 1129 GAATHGGWVTDLCFSPDGKMLISAG 1153
Score = 58.0 bits (134), Expect = 4e-08
Identities = 39/158 (24%), Positives = 71/158 (44%), Gaps = 1/158 (0%)
Frame = +2
Query: 308 ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSR 487
+S LS Y G + + + +L + + H K V + F+ D + ++S S
Sbjct: 921 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 980
Query: 488 DKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKL 664
D I++WN L +C + GH + V R N ++S +D TVKVW++
Sbjct: 981 DAEIQVWNWQLDKCIFL---RGHQETVKDFRLLKNSR---LLSWSFDGTVKVWNIITGNK 1034
Query: 665 KINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLN 778
+ + + H G + + +S D + +S D A +W +
Sbjct: 1035 EKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFD 1072
Score = 57.6 bits (133), Expect = 5e-08
Identities = 39/121 (32%), Positives = 57/121 (47%), Gaps = 2/121 (1%)
Frame = +2
Query: 422 HTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANP 601
HT V FS D ++I S DKT++++ K ++ H D V C FS + +
Sbjct: 614 HTDAVYRACFSEDGQRIASCGADKTLQVFKAETGEKL-LEIKAHEDEVLCCAFSTD--DR 670
Query: 602 IIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTV--TVSPDGSLCASGGKDMXAMLWDL 775
I +C D+ VK+W+ +L + HS +N T S L A+G D LWDL
Sbjct: 671 FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDL 730
Query: 776 N 778
N
Sbjct: 731 N 731
Score = 54.4 bits (125), Expect = 4e-07
Identities = 53/205 (25%), Positives = 91/205 (44%), Gaps = 15/205 (7%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYAL--SGSWDKTLR 376
I + S DK + +W E + + HS ++ ++ ++ L +GS D L+
Sbjct: 672 IATCSVDKKVKIWNSMTGELVHTYDE-----HSEQVNCCHFTNSSHHLLLATGSSDCFLK 726
Query: 377 LWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN-TLAECKYTIQ---- 541
LWDL + HT V FS D++ + S S D T+KLW+ T A + +I
Sbjct: 727 LWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQF 786
Query: 542 ----DDGHSDW---VSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL-GHSGYL 697
+D D V C +S + A ++ + + +W+ T+ + K+ GH ++
Sbjct: 787 FLNLEDPQEDMGVIVKCCSWSADGARIMVAA---KNKIFLWN-TDLRSKVADCRGHLSWV 842
Query: 698 NTVTVSPDGSLCASGGKDMXAMLWD 772
+ V SPDGS + D LW+
Sbjct: 843 HGVMFSPDGSSFLTSSDDQTIRLWE 867
Score = 52.0 bits (119), Expect = 2e-06
Identities = 44/179 (24%), Positives = 80/179 (44%), Gaps = 1/179 (0%)
Frame = +2
Query: 263 NYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLS 442
N I Q R + H + + ++D +S S D +++W+ K H + V
Sbjct: 949 NNRIFQSR-FQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIF-LRGHQETVKD 1006
Query: 443 VAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGW 622
+ N +++S S D T+K+WN + K +SC +H S
Sbjct: 1007 FRL-LKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSC---DISHDATKFSSTSA 1062
Query: 623 DRTVKVWHLTNCKLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
D+T K+W + L ++ L GH+G + S D +L A+G + +W++++G+ LH
Sbjct: 1063 DKTAKIWSF-DLLLPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLH 1120
Score = 42.3 bits (95), Expect = 0.002
Identities = 37/140 (26%), Positives = 57/140 (40%), Gaps = 8/140 (5%)
Frame = +2
Query: 134 RGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFIS 313
R T+ GH V +P ++ S S D TL +W T I K+ + +
Sbjct: 736 RNTMFGHTNSVNHCRFSPD-DKLLASCSADGTLKLWDATSANERKSINVKQFFLNLEDPQ 794
Query: 314 D---VVL-----SSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQ 469
+ V++ S+DG + + +K LW+ H V V FS D
Sbjct: 795 EDMGVIVKCCSWSADGARIMVAAKNKIF-LWNTDLRSKVADCRGHLSWVHGVMFSPDGSS 853
Query: 470 IVSGSRDKTIKLWNTLAECK 529
++ S D+TI+LW T CK
Sbjct: 854 FLTSSDDQTIRLWETKKVCK 873
>AJ243010-1|CAB55586.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 86.2 bits (204), Expect = 1e-16
Identities = 50/160 (31%), Positives = 78/160 (48%), Gaps = 1/160 (0%)
Frame = +2
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H+ + S DG S DKTL+++ G+ + H +VL AFS D+R I
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 673
Query: 476 SGSRDKTIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
+ S DK +K+WN++ E +T D HS+ V+C F+ + + ++ + D +K+W L
Sbjct: 674 TCSVDKKVKIWNSMTGELVHTY--DEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN 731
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ + GH+ N SPD L AS D LWD
Sbjct: 732 QKECRNTMFGHTNSANHCRFSPDDKLLASCSADGTLKLWD 771
Score = 66.5 bits (155), Expect = 1e-10
Identities = 57/205 (27%), Positives = 96/205 (46%), Gaps = 10/205 (4%)
Frame = +2
Query: 161 WVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGN 340
W Q + K ++SSS D + VW D+ + L GH + D L +
Sbjct: 964 WHIQFTADEK---TLISSSDDAEIQVWNWQLDKCIF------LRGHQETVKDFRLLKNSR 1014
Query: 341 YALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN-TL 517
LS S+D T+++W++ G + F H VLS S D + S S DKT K+W+ L
Sbjct: 1015 L-LSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDL 1073
Query: 518 AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR-TVKVWHLTNCKL-----KINHL 679
+ ++ GH+ V C FS + +++ G D +++W+++N +L ++
Sbjct: 1074 LLPLHELR--GHNGCVRCSAFS---VDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEE 1128
Query: 680 G---HSGYLNTVTVSPDGSLCASGG 745
G H G++ + SPDG + S G
Sbjct: 1129 GAATHGGWVTDLCFSPDGKMLISAG 1153
Score = 58.0 bits (134), Expect = 4e-08
Identities = 39/158 (24%), Positives = 71/158 (44%), Gaps = 1/158 (0%)
Frame = +2
Query: 308 ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSR 487
+S LS Y G + + + +L + + H K V + F+ D + ++S S
Sbjct: 921 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 980
Query: 488 DKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKL 664
D I++WN L +C + GH + V R N ++S +D TVKVW++
Sbjct: 981 DAEIQVWNWQLDKCIFL---RGHQETVKDFRLLKNSR---LLSWSFDGTVKVWNIITGNK 1034
Query: 665 KINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLN 778
+ + + H G + + +S D + +S D A +W +
Sbjct: 1035 EKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFD 1072
Score = 57.6 bits (133), Expect = 5e-08
Identities = 39/121 (32%), Positives = 57/121 (47%), Gaps = 2/121 (1%)
Frame = +2
Query: 422 HTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANP 601
HT V FS D ++I S DKT++++ K ++ H D V C FS + +
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKL-LEIKAHEDEVLCCAFSTD--DR 670
Query: 602 IIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTV--TVSPDGSLCASGGKDMXAMLWDL 775
I +C D+ VK+W+ +L + HS +N T S L A+G D LWDL
Sbjct: 671 FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDL 730
Query: 776 N 778
N
Sbjct: 731 N 731
Score = 52.8 bits (121), Expect = 1e-06
Identities = 50/204 (24%), Positives = 87/204 (42%), Gaps = 14/204 (6%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYAL--SGSWDKTLR 376
I + S DK + +W E + + HS ++ ++ ++ L +GS D L+
Sbjct: 672 IATCSVDKKVKIWNSMTGELVHTYDE-----HSEQVNCCHFTNSSHHLLLATGSSDCFLK 726
Query: 377 LWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN-TLAECKYTIQ---- 541
LWDL + HT FS D++ + S S D T+KLW+ T A + +I
Sbjct: 727 LWDLNQKECRNTMFGHTNSANHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQF 786
Query: 542 ----DDGHSDW---VSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLN 700
+D D V C +S + A ++ + + +W+ + + GH +++
Sbjct: 787 FLNLEDPQEDMEVIVKCCSWSADGARIMVAA---KNKIFLWNTDSRSKVADCRGHLSWVH 843
Query: 701 TVTVSPDGSLCASGGKDMXAMLWD 772
V SPDGS + D LW+
Sbjct: 844 GVMFSPDGSSFLTSSDDQTIRLWE 867
Score = 52.0 bits (119), Expect = 2e-06
Identities = 44/179 (24%), Positives = 80/179 (44%), Gaps = 1/179 (0%)
Frame = +2
Query: 263 NYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLS 442
N I Q R + H + + ++D +S S D +++W+ K H + V
Sbjct: 949 NNRIFQSR-FQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIF-LRGHQETVKD 1006
Query: 443 VAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGW 622
+ N +++S S D T+K+WN + K +SC +H S
Sbjct: 1007 FRL-LKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSC---DISHDATKFSSTSA 1062
Query: 623 DRTVKVWHLTNCKLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
D+T K+W + L ++ L GH+G + S D +L A+G + +W++++G+ LH
Sbjct: 1063 DKTAKIWSF-DLLLPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLH 1120
Score = 41.5 bits (93), Expect = 0.003
Identities = 36/140 (25%), Positives = 57/140 (40%), Gaps = 8/140 (5%)
Frame = +2
Query: 134 RGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFIS 313
R T+ GH +P ++ S S D TL +W T I K+ + +
Sbjct: 736 RNTMFGHTNSANHCRFSPD-DKLLASCSADGTLKLWDATSANERKSINVKQFFLNLEDPQ 794
Query: 314 D---VVL-----SSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQ 469
+ V++ S+DG + + +K LW+ + H V V FS D
Sbjct: 795 EDMEVIVKCCSWSADGARIMVAAKNKIF-LWNTDSRSKVADCRGHLSWVHGVMFSPDGSS 853
Query: 470 IVSGSRDKTIKLWNTLAECK 529
++ S D+TI+LW T CK
Sbjct: 854 FLTSSDDQTIRLWETKKVCK 873
>BC023662-1|AAH23662.2| 475|Homo sapiens RRP9, small subunit (SSU)
processome component, homolog (yeast) protein.
Length = 475
Score = 85.8 bits (203), Expect = 2e-16
Identities = 60/223 (26%), Positives = 103/223 (46%), Gaps = 6/223 (2%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLY------GHSH 304
LRGH +T + P I S+++D ++I W + + IP+ + GHS
Sbjct: 142 LRGHQLSITCLVVTPD-DSAIFSAAKDCSIIKWSVESGRKLHVIPRAKKGAEGKPPGHSS 200
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGS 484
+ + +SSDG Y SG K + +W+ + + F H V +AF Q+ S S
Sbjct: 201 HVLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTHQLYSTS 260
Query: 485 RDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKL 664
D+++K+WN +AE Y GH D V+ + + + G D TV+VW + +
Sbjct: 261 HDRSVKVWN-VAENSYVETLFGHQDAVAALDALSREC--CVTAGGRDGTVRVWKIPE-ES 316
Query: 665 KINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
++ GH G ++ + + + + SG D LW L+ + L
Sbjct: 317 QLVFYGHQGSIDCIHLINEEHM-VSGADDGSVALWGLSKKRPL 358
Score = 42.7 bits (96), Expect = 0.001
Identities = 32/138 (23%), Positives = 64/138 (46%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDV 319
T GH V+ +A + + S+S D+++ VW + EN+Y + L+GH ++ +
Sbjct: 236 TFTGHRDAVSGLAFR-RGTHQLYSTSHDRSVKVWNVA--ENSY---VETLFGHQDAVAAL 289
Query: 320 VLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTI 499
S +G D T+R+W + ++ F H + + ++ +VSG+ D ++
Sbjct: 290 DALSRECCVTAGGRDGTVRVWKIPE-ESQLVFYGHQGSIDCIHL-INEEHMVSGADDGSV 347
Query: 500 KLWNTLAECKYTIQDDGH 553
LW + +Q + H
Sbjct: 348 ALWGLSKKRPLALQREAH 365
Score = 33.9 bits (74), Expect = 0.68
Identities = 12/39 (30%), Positives = 22/39 (56%)
Frame = +2
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
GHS ++ + +S DG ASG + ++W+ +HL+
Sbjct: 197 GHSSHVLCMAISSDGKYLASGDRSKLILIWEAQSCQHLY 235
Score = 32.3 bits (70), Expect = 2.1
Identities = 13/39 (33%), Positives = 19/39 (48%)
Frame = +2
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
GH + + V+PD S S KD + W + G+ LH
Sbjct: 144 GHQLSITCLVVTPDDSAIFSAAKDCSIIKWSVESGRKLH 182
>BC010048-1|AAH10048.1| 475|Homo sapiens RRP9, small subunit (SSU)
processome component, homolog (yeast) protein.
Length = 475
Score = 85.8 bits (203), Expect = 2e-16
Identities = 60/223 (26%), Positives = 103/223 (46%), Gaps = 6/223 (2%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLY------GHSH 304
LRGH +T + P I S+++D ++I W + + IP+ + GHS
Sbjct: 142 LRGHQLSITCLVVTPD-DSAIFSAAKDCSIIKWSVESGRKLHVIPRAKKGAEGKPPGHSS 200
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGS 484
+ + +SSDG Y SG K + +W+ + + F H V +AF Q+ S S
Sbjct: 201 HVLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTHQLYSTS 260
Query: 485 RDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKL 664
D+++K+WN +AE Y GH D V+ + + + G D TV+VW + +
Sbjct: 261 HDRSVKVWN-VAENSYVETLFGHQDAVAALDALSREC--CVTAGGRDGTVRVWKIPE-ES 316
Query: 665 KINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
++ GH G ++ + + + + SG D LW L+ + L
Sbjct: 317 QLVFYGHQGSIDCIHLINEEHM-VSGADDGSVALWGLSKKRPL 358
Score = 42.7 bits (96), Expect = 0.001
Identities = 32/138 (23%), Positives = 64/138 (46%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDV 319
T GH V+ +A + + S+S D+++ VW + EN+Y + L+GH ++ +
Sbjct: 236 TFTGHRDAVSGLAFR-RGTHQLYSTSHDRSVKVWNVA--ENSY---VETLFGHQDAVAAL 289
Query: 320 VLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTI 499
S +G D T+R+W + ++ F H + + ++ +VSG+ D ++
Sbjct: 290 DALSRECCVTAGGRDGTVRVWKIPE-ESQLVFYGHQGSIDCIHL-INEEHMVSGADDGSV 347
Query: 500 KLWNTLAECKYTIQDDGH 553
LW + +Q + H
Sbjct: 348 ALWGLSKKRPLALQREAH 365
Score = 33.9 bits (74), Expect = 0.68
Identities = 12/39 (30%), Positives = 22/39 (56%)
Frame = +2
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
GHS ++ + +S DG ASG + ++W+ +HL+
Sbjct: 197 GHSSHVLCMAISSDGKYLASGDRSKLILIWEAQSCQHLY 235
Score = 32.3 bits (70), Expect = 2.1
Identities = 13/39 (33%), Positives = 19/39 (48%)
Frame = +2
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
GH + + V+PD S S KD + W + G+ LH
Sbjct: 144 GHQLSITCLVVTPDDSAIFSAAKDCSIIKWSVESGRKLH 182
>BC009879-1|AAH09879.1| 475|Homo sapiens RRP9, small subunit (SSU)
processome component, homolog (yeast) protein.
Length = 475
Score = 85.8 bits (203), Expect = 2e-16
Identities = 60/223 (26%), Positives = 103/223 (46%), Gaps = 6/223 (2%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLY------GHSH 304
LRGH +T + P I S+++D ++I W + + IP+ + GHS
Sbjct: 142 LRGHQLSITCLVVTPD-DSAIFSAAKDCSIIKWSVESGRKLHVIPRAKKGAEGKPPGHSS 200
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGS 484
+ + +SSDG Y SG K + +W+ + + F H V +AF Q+ S S
Sbjct: 201 HVLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTHQLYSTS 260
Query: 485 RDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKL 664
D+++K+WN +AE Y GH D V+ + + + G D TV+VW + +
Sbjct: 261 HDRSVKVWN-VAENSYVETLFGHQDAVAALDALSREC--CVTAGGRDGTVRVWKIPE-ES 316
Query: 665 KINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
++ GH G ++ + + + + SG D LW L+ + L
Sbjct: 317 QLVFYGHQGSIDCIHLINEEHM-VSGADDGSVALWGLSKKRPL 358
Score = 42.7 bits (96), Expect = 0.001
Identities = 32/138 (23%), Positives = 64/138 (46%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDV 319
T GH V+ +A + + S+S D+++ VW + EN+Y + L+GH ++ +
Sbjct: 236 TFTGHRDAVSGLAFR-RGTHQLYSTSHDRSVKVWNVA--ENSY---VETLFGHQDAVAAL 289
Query: 320 VLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTI 499
S +G D T+R+W + ++ F H + + ++ +VSG+ D ++
Sbjct: 290 DALSRECCVTAGGRDGTVRVWKIPE-ESQLVFYGHQGSIDCIHL-INEEHMVSGADDGSV 347
Query: 500 KLWNTLAECKYTIQDDGH 553
LW + +Q + H
Sbjct: 348 ALWGLSKKRPLALQREAH 365
Score = 33.9 bits (74), Expect = 0.68
Identities = 12/39 (30%), Positives = 22/39 (56%)
Frame = +2
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
GHS ++ + +S DG ASG + ++W+ +HL+
Sbjct: 197 GHSSHVLCMAISSDGKYLASGDRSKLILIWEAQSCQHLY 235
Score = 32.3 bits (70), Expect = 2.1
Identities = 13/39 (33%), Positives = 19/39 (48%)
Frame = +2
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
GH + + V+PD S S KD + W + G+ LH
Sbjct: 144 GHQLSITCLVVTPDDSAIFSAAKDCSIIKWSVESGRKLH 182
>BC001113-1|AAH01113.1| 475|Homo sapiens RRP9, small subunit (SSU)
processome component, homolog (yeast) protein.
Length = 475
Score = 85.8 bits (203), Expect = 2e-16
Identities = 60/223 (26%), Positives = 103/223 (46%), Gaps = 6/223 (2%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLY------GHSH 304
LRGH +T + P I S+++D ++I W + + IP+ + GHS
Sbjct: 142 LRGHQLSITCLVVTPD-DSAIFSAAKDCSIIKWSVESGRKLHVIPRAKKGAEGKPPGHSS 200
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGS 484
+ + +SSDG Y SG K + +W+ + + F H V +AF Q+ S S
Sbjct: 201 HVLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTHQLYSTS 260
Query: 485 RDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKL 664
D+++K+WN +AE Y GH D V+ + + + G D TV+VW + +
Sbjct: 261 HDRSVKVWN-VAENSYVETLFGHQDAVAALDALSREC--CVTAGGRDGTVRVWKIPE-ES 316
Query: 665 KINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
++ GH G ++ + + + + SG D LW L+ + L
Sbjct: 317 QLVFYGHQGSIDCIHLINEEHM-VSGADDGSVALWGLSKKRPL 358
Score = 42.7 bits (96), Expect = 0.001
Identities = 32/138 (23%), Positives = 64/138 (46%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDV 319
T GH V+ +A + + S+S D+++ VW + EN+Y + L+GH ++ +
Sbjct: 236 TFTGHRDAVSGLAFR-RGTHQLYSTSHDRSVKVWNVA--ENSY---VETLFGHQDAVAAL 289
Query: 320 VLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTI 499
S +G D T+R+W + ++ F H + + ++ +VSG+ D ++
Sbjct: 290 DALSRECCVTAGGRDGTVRVWKIPE-ESQLVFYGHQGSIDCIHL-INEEHMVSGADDGSV 347
Query: 500 KLWNTLAECKYTIQDDGH 553
LW + +Q + H
Sbjct: 348 ALWGLSKKRPLALQREAH 365
Score = 33.9 bits (74), Expect = 0.68
Identities = 12/39 (30%), Positives = 22/39 (56%)
Frame = +2
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
GHS ++ + +S DG ASG + ++W+ +HL+
Sbjct: 197 GHSSHVLCMAISSDGKYLASGDRSKLILIWEAQSCQHLY 235
Score = 32.3 bits (70), Expect = 2.1
Identities = 13/39 (33%), Positives = 19/39 (48%)
Frame = +2
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
GH + + V+PD S S KD + W + G+ LH
Sbjct: 144 GHQLSITCLVVTPDDSAIFSAAKDCSIIKWSVESGRKLH 182
>AJ001340-1|CAA04687.1| 475|Homo sapiens U3 snoRNP associated 55
kDa protein protein.
Length = 475
Score = 85.8 bits (203), Expect = 2e-16
Identities = 60/223 (26%), Positives = 103/223 (46%), Gaps = 6/223 (2%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLY------GHSH 304
LRGH +T + P I S+++D ++I W + + IP+ + GHS
Sbjct: 142 LRGHQLSITCLVVTPD-DSAIFSAAKDCSIIKWSVESGRKLHVIPRAKKGAEGKPPGHSS 200
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGS 484
+ + +SSDG Y SG K + +W+ + + F H V +AF Q+ S S
Sbjct: 201 HVLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTHQLYSTS 260
Query: 485 RDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKL 664
D+++K+WN +AE Y GH D V+ + + + G D TV+VW + +
Sbjct: 261 HDRSVKVWN-VAENSYVETLFGHQDAVAALDALSREC--CVTAGGRDGTVRVWKIPE-ES 316
Query: 665 KINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
++ GH G ++ + + + + SG D LW L+ + L
Sbjct: 317 QLVFYGHQGSIDCIHLINEEHM-VSGADDGSVALWGLSKKRPL 358
Score = 42.7 bits (96), Expect = 0.001
Identities = 32/138 (23%), Positives = 64/138 (46%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDV 319
T GH V+ +A + + S+S D+++ VW + EN+Y + L+GH ++ +
Sbjct: 236 TFTGHRDAVSGLAFR-RGTHQLYSTSHDRSVKVWNVA--ENSY---VETLFGHQDAVAAL 289
Query: 320 VLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTI 499
S +G D T+R+W + ++ F H + + ++ +VSG+ D ++
Sbjct: 290 DALSRECCVTAGGRDGTVRVWKIPE-ESQLVFYGHQGSIDCIHL-INEEHMVSGADDGSV 347
Query: 500 KLWNTLAECKYTIQDDGH 553
LW + +Q + H
Sbjct: 348 ALWGLSKKRPLALQREAH 365
Score = 33.9 bits (74), Expect = 0.68
Identities = 12/39 (30%), Positives = 22/39 (56%)
Frame = +2
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
GHS ++ + +S DG ASG + ++W+ +HL+
Sbjct: 197 GHSSHVLCMAISSDGKYLASGDRSKLILIWEAQSCQHLY 235
Score = 32.3 bits (70), Expect = 2.1
Identities = 13/39 (33%), Positives = 19/39 (48%)
Frame = +2
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
GH + + V+PD S S KD + W + G+ LH
Sbjct: 144 GHQLSITCLVVTPDDSAIFSAAKDCSIIKWSVESGRKLH 182
>AJ243007-1|CAB55583.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 85.4 bits (202), Expect = 2e-16
Identities = 49/160 (30%), Positives = 78/160 (48%), Gaps = 1/160 (0%)
Frame = +2
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H+ + S DG S DKT +++ G+ + H +VL AFS D+R I
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTFQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 673
Query: 476 SGSRDKTIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
+ S DK +K+WN++ E +T D HS+ V+C F+ + + ++ + D +K+W L
Sbjct: 674 TCSVDKKVKIWNSMTGELVHTY--DEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN 731
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ + GH+ +N SPD L AS D LWD
Sbjct: 732 QKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWD 771
Score = 66.5 bits (155), Expect = 1e-10
Identities = 57/205 (27%), Positives = 96/205 (46%), Gaps = 10/205 (4%)
Frame = +2
Query: 161 WVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGN 340
W Q + K ++SSS D + VW D+ + L GH + D L +
Sbjct: 964 WHIQFTADEK---TLISSSDDAEIQVWNWQLDKCIF------LRGHQETVKDFRLLKNSR 1014
Query: 341 YALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN-TL 517
LS S+D T+++W++ G + F H VLS S D + S S DKT K+W+ L
Sbjct: 1015 L-LSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDL 1073
Query: 518 AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR-TVKVWHLTNCKL-----KINHL 679
+ ++ GH+ V C FS + +++ G D +++W+++N +L ++
Sbjct: 1074 LLPLHELR--GHNGCVRCSAFS---VDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEE 1128
Query: 680 G---HSGYLNTVTVSPDGSLCASGG 745
G H G++ + SPDG + S G
Sbjct: 1129 GAATHGGWVTDLCFSPDGKMLISAG 1153
Score = 58.0 bits (134), Expect = 4e-08
Identities = 39/158 (24%), Positives = 71/158 (44%), Gaps = 1/158 (0%)
Frame = +2
Query: 308 ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSR 487
+S LS Y G + + + +L + + H K V + F+ D + ++S S
Sbjct: 921 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 980
Query: 488 DKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKL 664
D I++WN L +C + GH + V R N ++S +D TVKVW++
Sbjct: 981 DAEIQVWNWQLDKCIFL---RGHQETVKDFRLLKNSR---LLSWSFDGTVKVWNIITGNK 1034
Query: 665 KINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLN 778
+ + + H G + + +S D + +S D A +W +
Sbjct: 1035 EKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFD 1072
Score = 56.8 bits (131), Expect = 8e-08
Identities = 39/121 (32%), Positives = 56/121 (46%), Gaps = 2/121 (1%)
Frame = +2
Query: 422 HTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANP 601
HT V FS D ++I S DKT +++ K ++ H D V C FS + +
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTFQVFKAETGEKL-LEIKAHEDEVLCCAFSTD--DR 670
Query: 602 IIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTV--TVSPDGSLCASGGKDMXAMLWDL 775
I +C D+ VK+W+ +L + HS +N T S L A+G D LWDL
Sbjct: 671 FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDL 730
Query: 776 N 778
N
Sbjct: 731 N 731
Score = 54.4 bits (125), Expect = 4e-07
Identities = 51/204 (25%), Positives = 88/204 (43%), Gaps = 14/204 (6%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYAL--SGSWDKTLR 376
I + S DK + +W E + + HS ++ ++ ++ L +GS D L+
Sbjct: 672 IATCSVDKKVKIWNSMTGELVHTYDE-----HSEQVNCCHFTNSSHHLLLATGSSDCFLK 726
Query: 377 LWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN-TLAECKYTIQ---- 541
LWDL + HT V FS D++ + S S D T+KLW+ T A + +I
Sbjct: 727 LWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQF 786
Query: 542 ----DDGHSDW---VSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLN 700
+D D V C +S + A ++ + + +W+ + + GH +++
Sbjct: 787 FLNLEDPQEDMEVIVKCCSWSADGARIMVAA---KNKIFLWNTDSRSKVADCRGHLSWVH 843
Query: 701 TVTVSPDGSLCASGGKDMXAMLWD 772
V SPDGS + D LW+
Sbjct: 844 GVMFSPDGSSFLTSSDDQTIRLWE 867
Score = 52.0 bits (119), Expect = 2e-06
Identities = 44/179 (24%), Positives = 80/179 (44%), Gaps = 1/179 (0%)
Frame = +2
Query: 263 NYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLS 442
N I Q R + H + + ++D +S S D +++W+ K H + V
Sbjct: 949 NNRIFQSR-FQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIF-LRGHQETVKD 1006
Query: 443 VAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGW 622
+ N +++S S D T+K+WN + K +SC +H S
Sbjct: 1007 FRL-LKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSC---DISHDATKFSSTSA 1062
Query: 623 DRTVKVWHLTNCKLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
D+T K+W + L ++ L GH+G + S D +L A+G + +W++++G+ LH
Sbjct: 1063 DKTAKIWSF-DLLLPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLH 1120
Score = 43.2 bits (97), Expect = 0.001
Identities = 37/140 (26%), Positives = 58/140 (41%), Gaps = 8/140 (5%)
Frame = +2
Query: 134 RGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFIS 313
R T+ GH V +P ++ S S D TL +W T I K+ + +
Sbjct: 736 RNTMFGHTNSVNHCRFSPD-DKLLASCSADGTLKLWDATSANERKSINVKQFFLNLEDPQ 794
Query: 314 D---VVL-----SSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQ 469
+ V++ S+DG + + +K LW+ + H V V FS D
Sbjct: 795 EDMEVIVKCCSWSADGARIMVAAKNKIF-LWNTDSRSKVADCRGHLSWVHGVMFSPDGSS 853
Query: 470 IVSGSRDKTIKLWNTLAECK 529
++ S D+TI+LW T CK
Sbjct: 854 FLTSSDDQTIRLWETKKVCK 873
>AJ243107-1|CAB56462.1| 1171|Homo sapiens apoptotic protease
activating factor-1 protein.
Length = 1171
Score = 84.2 bits (199), Expect = 5e-16
Identities = 49/160 (30%), Positives = 78/160 (48%), Gaps = 1/160 (0%)
Frame = +2
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H+ + S DG S DKTL+++ G+ + H +VL AFS D+R I
Sbjct: 622 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 681
Query: 476 SGSRDKTIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
+ S DK +K+WN++ E +T D HS+ V+C F+ + + ++ + D +K+W L
Sbjct: 682 TCSVDKKVKIWNSMTGELVHTY--DEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN 739
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ + GH+ +N SPD AS D LWD
Sbjct: 740 QKECRNTMFGHTNSVNHCRFSPDDKPLASCSADGTLKLWD 779
Score = 65.7 bits (153), Expect = 2e-10
Identities = 42/164 (25%), Positives = 78/164 (47%), Gaps = 1/164 (0%)
Frame = +2
Query: 308 ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSR 487
+S LS Y G + + + +L + + H K V + F+ D + ++S S
Sbjct: 929 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 988
Query: 488 DKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKL 664
D I++WN L +C + GH + V R N ++S +D TVKVW++
Sbjct: 989 DAEIQVWNWQLDKCIFL---RGHQETVKDFRLLKNSR---LLSWSFDGTVKVWNIITGNK 1042
Query: 665 KINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
+ + + H G + + +S D + +S D A +W++++G+ LH
Sbjct: 1043 EKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWNVSNGELLH 1086
Score = 64.1 bits (149), Expect = 6e-10
Identities = 54/194 (27%), Positives = 86/194 (44%), Gaps = 7/194 (3%)
Frame = +2
Query: 161 WVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGN 340
W Q + K ++SSS D + VW D+ + L GH + D L +
Sbjct: 972 WHIQFTADEK---TLISSSDDAEIQVWNWQLDKCIF------LRGHQETVKDFRLLKNSR 1022
Query: 341 YALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNT-- 514
LS S+D T+++W++ G + F H VLS S D + S S DKT K+WN
Sbjct: 1023 L-LSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWNVSN 1081
Query: 515 --LAECKYTIQDDG---HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
L + ++G H WV+ + FSP+ +++S G +K W++ +
Sbjct: 1082 GELLHLCAPLSEEGAATHGGWVTDLCFSPD--GKMLISAG--GYIKWWNVVTGESSQTFY 1137
Query: 680 GHSGYLNTVTVSPD 721
+ L + VSPD
Sbjct: 1138 TNGTNLKKIHVSPD 1151
Score = 57.6 bits (133), Expect = 5e-08
Identities = 39/121 (32%), Positives = 57/121 (47%), Gaps = 2/121 (1%)
Frame = +2
Query: 422 HTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANP 601
HT V FS D ++I S DKT++++ K ++ H D V C FS + +
Sbjct: 622 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKL-LEIKAHEDEVLCCAFSTD--DR 678
Query: 602 IIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTV--TVSPDGSLCASGGKDMXAMLWDL 775
I +C D+ VK+W+ +L + HS +N T S L A+G D LWDL
Sbjct: 679 FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDL 738
Query: 776 N 778
N
Sbjct: 739 N 739
Score = 54.8 bits (126), Expect = 3e-07
Identities = 51/204 (25%), Positives = 88/204 (43%), Gaps = 14/204 (6%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYAL--SGSWDKTLR 376
I + S DK + +W E + + HS ++ ++ ++ L +GS D L+
Sbjct: 680 IATCSVDKKVKIWNSMTGELVHTYDE-----HSEQVNCCHFTNSSHHLLLATGSSDCFLK 734
Query: 377 LWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN-TLAECKYTIQ---- 541
LWDL + HT V FS D++ + S S D T+KLW+ T A + +I
Sbjct: 735 LWDLNQKECRNTMFGHTNSVNHCRFSPDDKPLASCSADGTLKLWDATSANERKSINVKQF 794
Query: 542 ----DDGHSDW---VSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLN 700
+D D V C +S + A ++ + + +W+ + + GH +++
Sbjct: 795 FLNLEDPQEDMEVIVKCCSWSADGARIMVAA---KNKIFLWNTDSRSKVADCRGHLSWVH 851
Query: 701 TVTVSPDGSLCASGGKDMXAMLWD 772
V SPDGS + D LW+
Sbjct: 852 GVMFSPDGSSFLTSSDDQTIRLWE 875
Score = 44.0 bits (99), Expect = 6e-04
Identities = 41/169 (24%), Positives = 73/169 (43%), Gaps = 8/169 (4%)
Frame = +2
Query: 263 NYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLS 442
N I Q R + H + + ++D +S S D +++W+ K H + V
Sbjct: 957 NNRIFQSR-FQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIF-LRGHQETVKD 1014
Query: 443 VAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGW 622
+ N +++S S D T+K+WN + K +SC +H S
Sbjct: 1015 FRL-LKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSC---DISHDATKFSSTSA 1070
Query: 623 DRTVKVWHLTNCKL-----KINHLG---HSGYLNTVTVSPDGSLCASGG 745
D+T K+W+++N +L ++ G H G++ + SPDG + S G
Sbjct: 1071 DKTAKIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAG 1119
Score = 41.5 bits (93), Expect = 0.003
Identities = 37/140 (26%), Positives = 57/140 (40%), Gaps = 8/140 (5%)
Frame = +2
Query: 134 RGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFIS 313
R T+ GH V +P + S S D TL +W T I K+ + +
Sbjct: 744 RNTMFGHTNSVNHCRFSPD-DKPLASCSADGTLKLWDATSANERKSINVKQFFLNLEDPQ 802
Query: 314 D---VVL-----SSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQ 469
+ V++ S+DG + + +K LW+ + H V V FS D
Sbjct: 803 EDMEVIVKCCSWSADGARIMVAAKNKIF-LWNTDSRSKVADCRGHLSWVHGVMFSPDGSS 861
Query: 470 IVSGSRDKTIKLWNTLAECK 529
++ S D+TI+LW T CK
Sbjct: 862 FLTSSDDQTIRLWETKKVCK 881
>AJ243008-1|CAB55584.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 83.8 bits (198), Expect = 6e-16
Identities = 49/160 (30%), Positives = 78/160 (48%), Gaps = 1/160 (0%)
Frame = +2
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H+ + S DG S DKTL+++ G+ + H +VL AFS D+R I
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 673
Query: 476 SGSRDKTIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
+ S DK +K+WN++ E +T D HS+ V+C F+ + + ++ + D +K+W L
Sbjct: 674 TCSVDKKVKIWNSMTGELVHTY--DEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN 731
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ + G + +N SPD L AS D LWD
Sbjct: 732 QKECRNTMFGRTNSVNHCRFSPDDKLLASCSADGTLKLWD 771
Score = 66.5 bits (155), Expect = 1e-10
Identities = 57/205 (27%), Positives = 96/205 (46%), Gaps = 10/205 (4%)
Frame = +2
Query: 161 WVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGN 340
W Q + K ++SSS D + VW D+ + L GH + D L +
Sbjct: 964 WHIQFTADEK---TLISSSDDAEIQVWNWQLDKCIF------LRGHQETVKDFRLLKNSR 1014
Query: 341 YALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN-TL 517
LS S+D T+++W++ G + F H VLS S D + S S DKT K+W+ L
Sbjct: 1015 L-LSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDL 1073
Query: 518 AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR-TVKVWHLTNCKL-----KINHL 679
+ ++ GH+ V C FS + +++ G D +++W+++N +L ++
Sbjct: 1074 LLPLHELR--GHNGCVRCSAFS---VDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEE 1128
Query: 680 G---HSGYLNTVTVSPDGSLCASGG 745
G H G++ + SPDG + S G
Sbjct: 1129 GAATHGGWVTDLCFSPDGKMLISAG 1153
Score = 58.0 bits (134), Expect = 4e-08
Identities = 39/158 (24%), Positives = 71/158 (44%), Gaps = 1/158 (0%)
Frame = +2
Query: 308 ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSR 487
+S LS Y G + + + +L + + H K V + F+ D + ++S S
Sbjct: 921 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 980
Query: 488 DKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKL 664
D I++WN L +C + GH + V R N ++S +D TVKVW++
Sbjct: 981 DAEIQVWNWQLDKCIFL---RGHQETVKDFRLLKNSR---LLSWSFDGTVKVWNIITGNK 1034
Query: 665 KINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLN 778
+ + + H G + + +S D + +S D A +W +
Sbjct: 1035 EKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFD 1072
Score = 57.6 bits (133), Expect = 5e-08
Identities = 39/121 (32%), Positives = 57/121 (47%), Gaps = 2/121 (1%)
Frame = +2
Query: 422 HTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANP 601
HT V FS D ++I S DKT++++ K ++ H D V C FS + +
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKL-LEIKAHEDEVLCCAFSTD--DR 670
Query: 602 IIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTV--TVSPDGSLCASGGKDMXAMLWDL 775
I +C D+ VK+W+ +L + HS +N T S L A+G D LWDL
Sbjct: 671 FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDL 730
Query: 776 N 778
N
Sbjct: 731 N 731
Score = 52.0 bits (119), Expect = 2e-06
Identities = 44/179 (24%), Positives = 80/179 (44%), Gaps = 1/179 (0%)
Frame = +2
Query: 263 NYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLS 442
N I Q R + H + + ++D +S S D +++W+ K H + V
Sbjct: 949 NNRIFQSR-FQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIF-LRGHQETVKD 1006
Query: 443 VAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGW 622
+ N +++S S D T+K+WN + K +SC +H S
Sbjct: 1007 FRL-LKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSC---DISHDATKFSSTSA 1062
Query: 623 DRTVKVWHLTNCKLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
D+T K+W + L ++ L GH+G + S D +L A+G + +W++++G+ LH
Sbjct: 1063 DKTAKIWSF-DLLLPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLH 1120
Score = 51.2 bits (117), Expect = 4e-06
Identities = 50/204 (24%), Positives = 87/204 (42%), Gaps = 14/204 (6%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYAL--SGSWDKTLR 376
I + S DK + +W E + + HS ++ ++ ++ L +GS D L+
Sbjct: 672 IATCSVDKKVKIWNSMTGELVHTYDE-----HSEQVNCCHFTNSSHHLLLATGSSDCFLK 726
Query: 377 LWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN-TLAECKYTIQ---- 541
LWDL + T V FS D++ + S S D T+KLW+ T A + +I
Sbjct: 727 LWDLNQKECRNTMFGRTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQF 786
Query: 542 ----DDGHSDW---VSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLN 700
+D D V C +S + A ++ + + +W+ + + GH +++
Sbjct: 787 FLNLEDPQEDMEVIVKCCSWSADGARIMVAA---KNKIFLWNTDSRSKVADCRGHLSWVH 843
Query: 701 TVTVSPDGSLCASGGKDMXAMLWD 772
V SPDGS + D LW+
Sbjct: 844 GVMFSPDGSSFLTSSDDQTIRLWE 867
Score = 39.9 bits (89), Expect = 0.010
Identities = 36/140 (25%), Positives = 57/140 (40%), Gaps = 8/140 (5%)
Frame = +2
Query: 134 RGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFIS 313
R T+ G V +P ++ S S D TL +W T I K+ + +
Sbjct: 736 RNTMFGRTNSVNHCRFSPD-DKLLASCSADGTLKLWDATSANERKSINVKQFFLNLEDPQ 794
Query: 314 D---VVL-----SSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQ 469
+ V++ S+DG + + +K LW+ + H V V FS D
Sbjct: 795 EDMEVIVKCCSWSADGARIMVAAKNKIF-LWNTDSRSKVADCRGHLSWVHGVMFSPDGSS 853
Query: 470 IVSGSRDKTIKLWNTLAECK 529
++ S D+TI+LW T CK
Sbjct: 854 FLTSSDDQTIRLWETKKVCK 873
>EF560718-1|ABQ59028.1| 1205|Homo sapiens APAF1 protein protein.
Length = 1205
Score = 83.0 bits (196), Expect = 1e-15
Identities = 49/160 (30%), Positives = 77/160 (48%), Gaps = 1/160 (0%)
Frame = +2
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H+ + S D S DKTL+++ G + H +VL AFS D+R I
Sbjct: 614 HTDAVYHACFSEDDQRIASCGADKTLQVFKAETGGKLLEIKAHEDEVLCCAFSTDDRFIA 673
Query: 476 SGSRDKTIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
+ S DK +K+WN++ E +T D HS+ V+C F+ + + ++ + D +K+W L
Sbjct: 674 TCSVDKKVKIWNSMTGELVHTY--DEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN 731
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ + GH+ +N SPD L AS D LWD
Sbjct: 732 QKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWD 771
Score = 66.5 bits (155), Expect = 1e-10
Identities = 57/205 (27%), Positives = 96/205 (46%), Gaps = 10/205 (4%)
Frame = +2
Query: 161 WVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGN 340
W Q + K ++SSS D + VW D+ + L GH + D L +
Sbjct: 964 WHIQFTADEK---TLISSSDDAEIQVWNWQLDKCIF------LRGHQETVKDFRLLKNSR 1014
Query: 341 YALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN-TL 517
LS S+D T+++W++ G + F H VLS S D + S S DKT K+W+ L
Sbjct: 1015 L-LSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDL 1073
Query: 518 AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR-TVKVWHLTNCKL-----KINHL 679
+ ++ GH+ V C FS + +++ G D +++W+++N +L ++
Sbjct: 1074 LLPLHELR--GHNGCVRCSAFS---VDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEE 1128
Query: 680 G---HSGYLNTVTVSPDGSLCASGG 745
G H G++ + SPDG + S G
Sbjct: 1129 GAATHGGWVTDLCFSPDGKMLISAG 1153
Score = 58.4 bits (135), Expect = 3e-08
Identities = 39/121 (32%), Positives = 58/121 (47%), Gaps = 2/121 (1%)
Frame = +2
Query: 422 HTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANP 601
HT V FS D+++I S DKT++++ K ++ H D V C FS + +
Sbjct: 614 HTDAVYHACFSEDDQRIASCGADKTLQVFKAETGGKL-LEIKAHEDEVLCCAFSTD--DR 670
Query: 602 IIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTV--TVSPDGSLCASGGKDMXAMLWDL 775
I +C D+ VK+W+ +L + HS +N T S L A+G D LWDL
Sbjct: 671 FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDL 730
Query: 776 N 778
N
Sbjct: 731 N 731
Score = 58.0 bits (134), Expect = 4e-08
Identities = 39/158 (24%), Positives = 71/158 (44%), Gaps = 1/158 (0%)
Frame = +2
Query: 308 ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSR 487
+S LS Y G + + + +L + + H K V + F+ D + ++S S
Sbjct: 921 VSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSD 980
Query: 488 DKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKL 664
D I++WN L +C + GH + V R N ++S +D TVKVW++
Sbjct: 981 DAEIQVWNWQLDKCIFL---RGHQETVKDFRLLKNSR---LLSWSFDGTVKVWNIITGNK 1034
Query: 665 KINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLN 778
+ + + H G + + +S D + +S D A +W +
Sbjct: 1035 EKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFD 1072
Score = 54.4 bits (125), Expect = 4e-07
Identities = 51/204 (25%), Positives = 88/204 (43%), Gaps = 14/204 (6%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYAL--SGSWDKTLR 376
I + S DK + +W E + + HS ++ ++ ++ L +GS D L+
Sbjct: 672 IATCSVDKKVKIWNSMTGELVHTYDE-----HSEQVNCCHFTNSSHHLLLATGSSDCFLK 726
Query: 377 LWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN-TLAECKYTIQ---- 541
LWDL + HT V FS D++ + S S D T+KLW+ T A + +I
Sbjct: 727 LWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQF 786
Query: 542 ----DDGHSDW---VSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLN 700
+D D V C +S + A ++ + + +W+ + + GH +++
Sbjct: 787 FLNLEDPQEDMEVIVKCCSWSADGARIMVAA---KNKIFLWNTDSRSKVADCRGHLSWVH 843
Query: 701 TVTVSPDGSLCASGGKDMXAMLWD 772
V SPDGS + D LW+
Sbjct: 844 GVMFSPDGSSFLTSSDDQTIRLWE 867
Score = 52.0 bits (119), Expect = 2e-06
Identities = 44/179 (24%), Positives = 80/179 (44%), Gaps = 1/179 (0%)
Frame = +2
Query: 263 NYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLS 442
N I Q R + H + + ++D +S S D +++W+ K H + V
Sbjct: 949 NNRIFQSR-FQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIF-LRGHQETVKD 1006
Query: 443 VAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGW 622
+ N +++S S D T+K+WN + K +SC +H S
Sbjct: 1007 FRL-LKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSC---DISHDATKFSSTSA 1062
Query: 623 DRTVKVWHLTNCKLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
D+T K+W + L ++ L GH+G + S D +L A+G + +W++++G+ LH
Sbjct: 1063 DKTAKIWSF-DLLLPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLH 1120
Score = 43.2 bits (97), Expect = 0.001
Identities = 37/140 (26%), Positives = 58/140 (41%), Gaps = 8/140 (5%)
Frame = +2
Query: 134 RGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFIS 313
R T+ GH V +P ++ S S D TL +W T I K+ + +
Sbjct: 736 RNTMFGHTNSVNHCRFSPD-DKLLASCSADGTLKLWDATSANERKSINVKQFFLNLEDPQ 794
Query: 314 D---VVL-----SSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQ 469
+ V++ S+DG + + +K LW+ + H V V FS D
Sbjct: 795 EDMEVIVKCCSWSADGARIMVAAKNKIF-LWNTDSRSKVADCRGHLSWVHGVMFSPDGSS 853
Query: 470 IVSGSRDKTIKLWNTLAECK 529
++ S D+TI+LW T CK
Sbjct: 854 FLTSSDDQTIRLWETKKVCK 873
>Y12781-1|CAA73319.1| 577|Homo sapiens transducin (beta) like 1
protein protein.
Length = 577
Score = 79.8 bits (188), Expect = 1e-14
Identities = 62/235 (26%), Positives = 104/235 (44%), Gaps = 8/235 (3%)
Frame = +2
Query: 116 SETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
+E L TL H G + + N K + ILS+ DKT I+W E P
Sbjct: 316 TEDGNLASTLGQHKGPIFALKWNRK-GNYILSAGVDKTTIIWDAHTGEAKQQFPF----- 369
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
HS DV ++ +A S S D + + L + + F+ HT +V ++ + +
Sbjct: 370 HSAPALDVDWQNNTTFA-SCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLA 428
Query: 476 SGSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPN-------HANPIIVSCGWDRT 631
S S D T+K+W+ E C + +Q H+ + +++SP ++N ++ S +D T
Sbjct: 429 SCSDDMTLKIWSMKQEVCIHDLQ--AHNKEIYTIKWSPTGPATSNPNSNIMLASASFDST 486
Query: 632 VKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
V++W + H + +V SPDG ASG D +W+ G +H
Sbjct: 487 VRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGNLVH 541
Score = 51.2 bits (117), Expect = 4e-06
Identities = 41/177 (23%), Positives = 74/177 (41%), Gaps = 10/177 (5%)
Frame = +2
Query: 275 PQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFS 454
P K GH++ ++ + G S S D TL++W + + H K++ ++ +S
Sbjct: 404 PVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWS 463
Query: 455 V---------DNRQIVSGSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPI 604
N + S S D T++LW+ C +T+ H + V V FSP+
Sbjct: 464 PTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTK--HQEPVYSVAFSPD--GKY 519
Query: 605 IVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
+ S +D+ V +W+ + L ++ G G V + G + D + DL
Sbjct: 520 LASGSFDKCVHIWNTQSGNLVHSYRGTGGIFE-VCWNARGDKVGASASDGSVCVLDL 575
Score = 48.0 bits (109), Expect = 4e-05
Identities = 27/107 (25%), Positives = 50/107 (46%)
Frame = +2
Query: 179 TNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGS 358
+NP M+ S+S D T+ +W + R G+ L H + V S DG Y SGS
Sbjct: 470 SNPNSNIMLASASFDSTVRLWDIER-----GVCTHTLTKHQEPVYSVAFSPDGKYLASGS 524
Query: 359 WDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTI 499
+DK + +W+ +G + T + V ++ ++ + + D ++
Sbjct: 525 FDKCVHIWNTQSGNLVHSYRG-TGGIFEVCWNARGDKVGASASDGSV 570
Score = 33.5 bits (73), Expect = 0.90
Identities = 29/134 (21%), Positives = 55/134 (41%), Gaps = 12/134 (8%)
Frame = +2
Query: 422 HTKDVLSVAFSVDNRQIVSGSRDKTIKLWN---------TLAECKYTIQDDGHS--DWVS 568
H +V A++ + + SGS D T ++WN T ++ I++ GH
Sbjct: 231 HESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKD 290
Query: 569 CVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLG-HSGYLNTVTVSPDGSLCASGG 745
N ++ + +D ++W T + LG H G + + + G+ S G
Sbjct: 291 VTSLDWNTNGTLLATGSYDGFARIW--TEDGNLASTLGQHKGPIFALKWNRKGNYILSAG 348
Query: 746 KDMXAMLWDLNDGK 787
D ++WD + G+
Sbjct: 349 VDKTTIIWDAHTGE 362
Score = 32.7 bits (71), Expect = 1.6
Identities = 31/133 (23%), Positives = 55/133 (41%), Gaps = 14/133 (10%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDL---AAGKTTRRFEDH----------- 424
L GH + + + SGS D T R+W+L + G +T+ H
Sbjct: 228 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 287
Query: 425 TKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPI 604
KDV S+ ++ + + +GS D ++W T+ H + +++ N
Sbjct: 288 NKDVTSLDWNTNGTLLATGSYDGFARIWTEDGNLASTLGQ--HKGPIFALKW--NRKGNY 343
Query: 605 IVSCGWDRTVKVW 643
I+S G D+T +W
Sbjct: 344 ILSAGVDKTTIIW 356
>BC052304-1|AAH52304.1| 577|Homo sapiens transducin (beta)-like
1X-linked protein.
Length = 577
Score = 79.8 bits (188), Expect = 1e-14
Identities = 62/235 (26%), Positives = 104/235 (44%), Gaps = 8/235 (3%)
Frame = +2
Query: 116 SETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
+E L TL H G + + N K + ILS+ DKT I+W E P
Sbjct: 316 TEDGNLASTLGQHKGPIFALKWNRK-GNYILSAGVDKTTIIWDAHTGEAKQQFPF----- 369
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
HS DV ++ +A S S D + + L + + F+ HT +V ++ + +
Sbjct: 370 HSAPALDVDWQNNTTFA-SCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLA 428
Query: 476 SGSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPN-------HANPIIVSCGWDRT 631
S S D T+K+W+ E C + +Q H+ + +++SP ++N ++ S +D T
Sbjct: 429 SCSDDMTLKIWSMKQEVCIHDLQ--AHNKEIYTIKWSPTGPATSNPNSNIMLASASFDST 486
Query: 632 VKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
V++W + H + +V SPDG ASG D +W+ G +H
Sbjct: 487 VRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGNLVH 541
Score = 51.2 bits (117), Expect = 4e-06
Identities = 41/177 (23%), Positives = 74/177 (41%), Gaps = 10/177 (5%)
Frame = +2
Query: 275 PQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFS 454
P K GH++ ++ + G S S D TL++W + + H K++ ++ +S
Sbjct: 404 PVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWS 463
Query: 455 V---------DNRQIVSGSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPI 604
N + S S D T++LW+ C +T+ H + V V FSP+
Sbjct: 464 PTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTK--HQEPVYSVAFSPD--GKY 519
Query: 605 IVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
+ S +D+ V +W+ + L ++ G G V + G + D + DL
Sbjct: 520 LASGSFDKCVHIWNTQSGNLVHSYRGTGGIFE-VCWNARGDKVGASASDGSVCVLDL 575
Score = 48.0 bits (109), Expect = 4e-05
Identities = 27/107 (25%), Positives = 50/107 (46%)
Frame = +2
Query: 179 TNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGS 358
+NP M+ S+S D T+ +W + R G+ L H + V S DG Y SGS
Sbjct: 470 SNPNSNIMLASASFDSTVRLWDIER-----GVCTHTLTKHQEPVYSVAFSPDGKYLASGS 524
Query: 359 WDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTI 499
+DK + +W+ +G + T + V ++ ++ + + D ++
Sbjct: 525 FDKCVHIWNTQSGNLVHSYRG-TGGIFEVCWNARGDKVGASASDGSV 570
Score = 33.5 bits (73), Expect = 0.90
Identities = 29/134 (21%), Positives = 55/134 (41%), Gaps = 12/134 (8%)
Frame = +2
Query: 422 HTKDVLSVAFSVDNRQIVSGSRDKTIKLWN---------TLAECKYTIQDDGHS--DWVS 568
H +V A++ + + SGS D T ++WN T ++ I++ GH
Sbjct: 231 HESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKD 290
Query: 569 CVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLG-HSGYLNTVTVSPDGSLCASGG 745
N ++ + +D ++W T + LG H G + + + G+ S G
Sbjct: 291 VTSLDWNTNGTLLATGSYDGFARIW--TEDGNLASTLGQHKGPIFALKWNRKGNYILSAG 348
Query: 746 KDMXAMLWDLNDGK 787
D ++WD + G+
Sbjct: 349 VDKTTIIWDAHTGE 362
Score = 32.7 bits (71), Expect = 1.6
Identities = 31/133 (23%), Positives = 55/133 (41%), Gaps = 14/133 (10%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDL---AAGKTTRRFEDH----------- 424
L GH + + + SGS D T R+W+L + G +T+ H
Sbjct: 228 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 287
Query: 425 TKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPI 604
KDV S+ ++ + + +GS D ++W T+ H + +++ N
Sbjct: 288 NKDVTSLDWNTNGTLLATGSYDGFARIWTEDGNLASTLGQ--HKGPIFALKW--NRKGNY 343
Query: 605 IVSCGWDRTVKVW 643
I+S G D+T +W
Sbjct: 344 ILSAGVDKTTIIW 356
>BC032708-1|AAH32708.1| 526|Homo sapiens TBL1X protein protein.
Length = 526
Score = 79.8 bits (188), Expect = 1e-14
Identities = 62/235 (26%), Positives = 104/235 (44%), Gaps = 8/235 (3%)
Frame = +2
Query: 116 SETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
+E L TL H G + + N K + ILS+ DKT I+W E P
Sbjct: 265 TEDGNLASTLGQHKGPIFALKWNRK-GNYILSAGVDKTTIIWDAHTGEAKQQFPF----- 318
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
HS DV ++ +A S S D + + L + + F+ HT +V ++ + +
Sbjct: 319 HSAPALDVDWQNNTTFA-SCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLA 377
Query: 476 SGSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPN-------HANPIIVSCGWDRT 631
S S D T+K+W+ E C + +Q H+ + +++SP ++N ++ S +D T
Sbjct: 378 SCSDDMTLKIWSMKQEVCIHDLQ--AHNKEIYTIKWSPTGPATSNPNSNIMLASASFDST 435
Query: 632 VKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
V++W + H + +V SPDG ASG D +W+ G +H
Sbjct: 436 VRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGNLVH 490
Score = 51.2 bits (117), Expect = 4e-06
Identities = 41/177 (23%), Positives = 74/177 (41%), Gaps = 10/177 (5%)
Frame = +2
Query: 275 PQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFS 454
P K GH++ ++ + G S S D TL++W + + H K++ ++ +S
Sbjct: 353 PVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWS 412
Query: 455 V---------DNRQIVSGSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPI 604
N + S S D T++LW+ C +T+ H + V V FSP+
Sbjct: 413 PTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTK--HQEPVYSVAFSPD--GKY 468
Query: 605 IVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
+ S +D+ V +W+ + L ++ G G V + G + D + DL
Sbjct: 469 LASGSFDKCVHIWNTQSGNLVHSYRGTGGIFE-VCWNARGDKVGASASDGSVCVLDL 524
Score = 48.0 bits (109), Expect = 4e-05
Identities = 27/107 (25%), Positives = 50/107 (46%)
Frame = +2
Query: 179 TNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGS 358
+NP M+ S+S D T+ +W + R G+ L H + V S DG Y SGS
Sbjct: 419 SNPNSNIMLASASFDSTVRLWDIER-----GVCTHTLTKHQEPVYSVAFSPDGKYLASGS 473
Query: 359 WDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTI 499
+DK + +W+ +G + T + V ++ ++ + + D ++
Sbjct: 474 FDKCVHIWNTQSGNLVHSYRG-TGGIFEVCWNARGDKVGASASDGSV 519
Score = 33.5 bits (73), Expect = 0.90
Identities = 29/134 (21%), Positives = 55/134 (41%), Gaps = 12/134 (8%)
Frame = +2
Query: 422 HTKDVLSVAFSVDNRQIVSGSRDKTIKLWN---------TLAECKYTIQDDGHS--DWVS 568
H +V A++ + + SGS D T ++WN T ++ I++ GH
Sbjct: 180 HESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKD 239
Query: 569 CVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLG-HSGYLNTVTVSPDGSLCASGG 745
N ++ + +D ++W T + LG H G + + + G+ S G
Sbjct: 240 VTSLDWNTNGTLLATGSYDGFARIW--TEDGNLASTLGQHKGPIFALKWNRKGNYILSAG 297
Query: 746 KDMXAMLWDLNDGK 787
D ++WD + G+
Sbjct: 298 VDKTTIIWDAHTGE 311
Score = 32.7 bits (71), Expect = 1.6
Identities = 31/133 (23%), Positives = 55/133 (41%), Gaps = 14/133 (10%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDL---AAGKTTRRFEDH----------- 424
L GH + + + SGS D T R+W+L + G +T+ H
Sbjct: 177 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 236
Query: 425 TKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPI 604
KDV S+ ++ + + +GS D ++W T+ H + +++ N
Sbjct: 237 NKDVTSLDWNTNGTLLATGSYDGFARIWTEDGNLASTLGQ--HKGPIFALKW--NRKGNY 292
Query: 605 IVSCGWDRTVKVW 643
I+S G D+T +W
Sbjct: 293 ILSAGVDKTTIIW 305
>AB209608-1|BAD92845.1| 540|Homo sapiens transducin beta-like 1X
variant protein.
Length = 540
Score = 79.8 bits (188), Expect = 1e-14
Identities = 62/235 (26%), Positives = 104/235 (44%), Gaps = 8/235 (3%)
Frame = +2
Query: 116 SETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
+E L TL H G + + N K + ILS+ DKT I+W E P
Sbjct: 279 TEDGNLASTLGQHKGPIFALKWNRK-GNYILSAGVDKTTIIWDAHTGEAKQQFPF----- 332
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
HS DV ++ +A S S D + + L + + F+ HT +V ++ + +
Sbjct: 333 HSAPALDVDWQNNTTFA-SCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLA 391
Query: 476 SGSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPN-------HANPIIVSCGWDRT 631
S S D T+K+W+ E C + +Q H+ + +++SP ++N ++ S +D T
Sbjct: 392 SCSDDMTLKIWSMKQEVCIHDLQ--AHNKEIYTIKWSPTGPATSNPNSNIMLASASFDST 449
Query: 632 VKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
V++W + H + +V SPDG ASG D +W+ G +H
Sbjct: 450 VRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGNLVH 504
Score = 51.2 bits (117), Expect = 4e-06
Identities = 41/177 (23%), Positives = 74/177 (41%), Gaps = 10/177 (5%)
Frame = +2
Query: 275 PQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFS 454
P K GH++ ++ + G S S D TL++W + + H K++ ++ +S
Sbjct: 367 PVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWS 426
Query: 455 V---------DNRQIVSGSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPI 604
N + S S D T++LW+ C +T+ H + V V FSP+
Sbjct: 427 PTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTK--HQEPVYSVAFSPD--GKY 482
Query: 605 IVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
+ S +D+ V +W+ + L ++ G G V + G + D + DL
Sbjct: 483 LASGSFDKCVHIWNTQSGNLVHSYRGTGGIFE-VCWNARGDKVGASASDGSVCVLDL 538
Score = 48.0 bits (109), Expect = 4e-05
Identities = 27/107 (25%), Positives = 50/107 (46%)
Frame = +2
Query: 179 TNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGS 358
+NP M+ S+S D T+ +W + R G+ L H + V S DG Y SGS
Sbjct: 433 SNPNSNIMLASASFDSTVRLWDIER-----GVCTHTLTKHQEPVYSVAFSPDGKYLASGS 487
Query: 359 WDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTI 499
+DK + +W+ +G + T + V ++ ++ + + D ++
Sbjct: 488 FDKCVHIWNTQSGNLVHSYRG-TGGIFEVCWNARGDKVGASASDGSV 533
Score = 33.5 bits (73), Expect = 0.90
Identities = 29/134 (21%), Positives = 55/134 (41%), Gaps = 12/134 (8%)
Frame = +2
Query: 422 HTKDVLSVAFSVDNRQIVSGSRDKTIKLWN---------TLAECKYTIQDDGHS--DWVS 568
H +V A++ + + SGS D T ++WN T ++ I++ GH
Sbjct: 194 HESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKD 253
Query: 569 CVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLG-HSGYLNTVTVSPDGSLCASGG 745
N ++ + +D ++W T + LG H G + + + G+ S G
Sbjct: 254 VTSLDWNTNGTLLATGSYDGFARIW--TEDGNLASTLGQHKGPIFALKWNRKGNYILSAG 311
Query: 746 KDMXAMLWDLNDGK 787
D ++WD + G+
Sbjct: 312 VDKTTIIWDAHTGE 325
Score = 32.7 bits (71), Expect = 1.6
Identities = 31/133 (23%), Positives = 55/133 (41%), Gaps = 14/133 (10%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDL---AAGKTTRRFEDH----------- 424
L GH + + + SGS D T R+W+L + G +T+ H
Sbjct: 191 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 250
Query: 425 TKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPI 604
KDV S+ ++ + + +GS D ++W T+ H + +++ N
Sbjct: 251 NKDVTSLDWNTNGTLLATGSYDGFARIWTEDGNLASTLGQ--HKGPIFALKW--NRKGNY 306
Query: 605 IVSCGWDRTVKVW 643
I+S G D+T +W
Sbjct: 307 ILSAGVDKTTIIW 319
>BC130473-1|AAI30474.1| 522|Homo sapiens transducin (beta)-like
1Y-linked protein.
Length = 522
Score = 79.4 bits (187), Expect = 1e-14
Identities = 62/235 (26%), Positives = 104/235 (44%), Gaps = 8/235 (3%)
Frame = +2
Query: 116 SETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
+E L TL H G + + N K + +LS+ DKT I+W E P
Sbjct: 263 TENGNLASTLGQHKGPIFALKWNKK-GNYVLSAGVDKTTIIWDAHTGEAKQQFPF----- 316
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
HS DV ++ +A S S D + + L + F+ HT +V ++ + +
Sbjct: 317 HSAPALDVDWQNNMTFA-SCSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGMLLA 375
Query: 476 SGSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNH---ANP----IIVSCGWDRT 631
S S D T+K+W+ + C + +Q HS + +++SP +NP ++ S +D T
Sbjct: 376 SCSDDMTLKIWSMKQDACVHDLQ--AHSKEIYTIKWSPTGPATSNPNSSIMLASASFDST 433
Query: 632 VKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
V++W + + H + +V SPDG ASG D +W+ G +H
Sbjct: 434 VRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVH 488
Score = 47.2 bits (107), Expect = 7e-05
Identities = 26/107 (24%), Positives = 51/107 (47%)
Frame = +2
Query: 179 TNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGS 358
+NP M+ S+S D T+ +W + + G+ L H + V S DG Y SGS
Sbjct: 417 SNPNSSIMLASASFDSTVRLWDVEQ-----GVCTHTLMKHQEPVYSVAFSPDGKYLASGS 471
Query: 359 WDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTI 499
+DK + +W+ +G ++ T + V ++ ++ + + D ++
Sbjct: 472 FDKYVHIWNTQSGSLVHSYQG-TGGIFEVCWNARGDKVGASASDGSV 517
Score = 34.7 bits (76), Expect = 0.39
Identities = 28/133 (21%), Positives = 52/133 (39%), Gaps = 11/133 (8%)
Frame = +2
Query: 422 HTKDVLSVAFSVDNRQIVSGSRDKTIKLWN---------TLAECKYTIQDDGHS--DWVS 568
H +V A++ + + SGS D T ++WN T ++ I++ GH
Sbjct: 178 HESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKD 237
Query: 569 CVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGK 748
N ++ +D ++W N L H G + + + G+ S G
Sbjct: 238 VTSLDWNSDGTLLAMGSYDGFARIW-TENGNLASTLGQHKGPIFALKWNKKGNYVLSAGV 296
Query: 749 DMXAMLWDLNDGK 787
D ++WD + G+
Sbjct: 297 DKTTIIWDAHTGE 309
Score = 32.7 bits (71), Expect = 1.6
Identities = 31/133 (23%), Positives = 54/133 (40%), Gaps = 14/133 (10%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDL---AAGKTTRRFEDH----------- 424
L GH + + + SGS D T R+W+L + G +T+ H
Sbjct: 175 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 234
Query: 425 TKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPI 604
KDV S+ ++ D + GS D ++W T+ H + +++ N
Sbjct: 235 NKDVTSLDWNSDGTLLAMGSYDGFARIWTENGNLASTLGQ--HKGPIFALKW--NKKGNY 290
Query: 605 IVSCGWDRTVKVW 643
++S G D+T +W
Sbjct: 291 VLSAGVDKTTIIW 303
>BC130471-1|AAI30472.1| 522|Homo sapiens transducin (beta)-like
1Y-linked protein.
Length = 522
Score = 79.4 bits (187), Expect = 1e-14
Identities = 62/235 (26%), Positives = 104/235 (44%), Gaps = 8/235 (3%)
Frame = +2
Query: 116 SETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
+E L TL H G + + N K + +LS+ DKT I+W E P
Sbjct: 263 TENGNLASTLGQHKGPIFALKWNKK-GNYVLSAGVDKTTIIWDAHTGEAKQQFPF----- 316
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
HS DV ++ +A S S D + + L + F+ HT +V ++ + +
Sbjct: 317 HSAPALDVDWQNNMTFA-SCSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGMLLA 375
Query: 476 SGSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNH---ANP----IIVSCGWDRT 631
S S D T+K+W+ + C + +Q HS + +++SP +NP ++ S +D T
Sbjct: 376 SCSDDMTLKIWSMKQDACVHDLQ--AHSKEIYTIKWSPTGPATSNPNSSIMLASASFDST 433
Query: 632 VKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
V++W + + H + +V SPDG ASG D +W+ G +H
Sbjct: 434 VRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVH 488
Score = 47.2 bits (107), Expect = 7e-05
Identities = 26/107 (24%), Positives = 51/107 (47%)
Frame = +2
Query: 179 TNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGS 358
+NP M+ S+S D T+ +W + + G+ L H + V S DG Y SGS
Sbjct: 417 SNPNSSIMLASASFDSTVRLWDVEQ-----GVCTHTLMKHQEPVYSVAFSPDGKYLASGS 471
Query: 359 WDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTI 499
+DK + +W+ +G ++ T + V ++ ++ + + D ++
Sbjct: 472 FDKYVHIWNTQSGSLVHSYQG-TGGIFEVCWNARGDKVGASASDGSV 517
Score = 34.7 bits (76), Expect = 0.39
Identities = 28/133 (21%), Positives = 52/133 (39%), Gaps = 11/133 (8%)
Frame = +2
Query: 422 HTKDVLSVAFSVDNRQIVSGSRDKTIKLWN---------TLAECKYTIQDDGHS--DWVS 568
H +V A++ + + SGS D T ++WN T ++ I++ GH
Sbjct: 178 HESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKD 237
Query: 569 CVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGK 748
N ++ +D ++W N L H G + + + G+ S G
Sbjct: 238 VTSLDWNSDGTLLAMGSYDGFARIW-TENGNLASTLGQHKGPIFALKWNKKGNYVLSAGV 296
Query: 749 DMXAMLWDLNDGK 787
D ++WD + G+
Sbjct: 297 DKTTIIWDAHTGE 309
Score = 32.7 bits (71), Expect = 1.6
Identities = 31/133 (23%), Positives = 54/133 (40%), Gaps = 14/133 (10%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDL---AAGKTTRRFEDH----------- 424
L GH + + + SGS D T R+W+L + G +T+ H
Sbjct: 175 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 234
Query: 425 TKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPI 604
KDV S+ ++ D + GS D ++W T+ H + +++ N
Sbjct: 235 NKDVTSLDWNSDGTLLAMGSYDGFARIWTENGNLASTLGQ--HKGPIFALKW--NKKGNY 290
Query: 605 IVSCGWDRTVKVW 643
++S G D+T +W
Sbjct: 291 VLSAGVDKTTIIW 303
>BC113421-1|AAI13422.1| 514|Homo sapiens transducin (beta)-like
1X-linked receptor 1 protein.
Length = 514
Score = 79.4 bits (187), Expect = 1e-14
Identities = 62/230 (26%), Positives = 102/230 (44%), Gaps = 8/230 (3%)
Frame = +2
Query: 131 LRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFI 310
L TL H G + + N K + ILS+ DKT I+W E P HS
Sbjct: 258 LASTLGQHKGPIFALKWNKK-GNFILSAGVDKTTIIWDAHTGEAKQQFPF-----HSAPA 311
Query: 311 SDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRD 490
DV S+ +A S S D + + L + + F+ HT +V ++ + + S S D
Sbjct: 312 LDVDWQSNNTFA-SCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDD 370
Query: 491 KTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPN-------HANPIIVSCGWDRTVKVWH 646
T+K+W+ + C + +Q H+ + +++SP +AN ++ S +D TV++W
Sbjct: 371 MTLKIWSMKQDNCVHDLQ--AHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWD 428
Query: 647 LTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
+ H + +V SPDG ASG D +W+ G +H
Sbjct: 429 VDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVH 478
Score = 60.1 bits (139), Expect = 9e-09
Identities = 57/229 (24%), Positives = 91/229 (39%), Gaps = 11/229 (4%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRL----------Y 292
LRGH V A NP D++ S S D T +W L+ + + G Q L
Sbjct: 165 LRGHESEVFICAWNP-VSDLLASGSGDSTARIWNLSENSTS-GSTQLVLRHCIREGGQDV 222
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI 472
+ ++ + +S+G +GS+D R+W G H + ++ ++ I
Sbjct: 223 PSNKDVTSLDWNSEGTLLATGSYDGFARIWT-KDGNLASTLGQHKGPIFALKWNKKGNFI 281
Query: 473 VSGSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 649
+S DKT +W+ E K Q HS V + N+ SC D + V L
Sbjct: 282 LSAGVDKTTIIWDAHTGEAKQ--QFPFHSAPALDVDWQSNNT---FASCSTDMCIHVCKL 336
Query: 650 TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
+ GH+ +N + P G+L AS DM +W + +H
Sbjct: 337 GQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVH 385
Score = 55.6 bits (128), Expect = 2e-07
Identities = 49/199 (24%), Positives = 83/199 (41%), Gaps = 10/199 (5%)
Frame = +2
Query: 209 SSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDL 388
S S D + V KL +D P K GH++ ++ + GN S S D TL++W +
Sbjct: 324 SCSTDMCIHVCKLGQDR-----PIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSM 378
Query: 389 AAGKTTRRFEDHTKDVLSVAFSVD---------NRQIVSGSRDKTIKLWNT-LAECKYTI 538
+ H K++ ++ +S N + S S D T++LW+ C +T+
Sbjct: 379 KQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTL 438
Query: 539 QDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSP 718
H + V V FSP+ + S +D+ V +W+ L ++ G G V +
Sbjct: 439 TK--HQEPVYSVAFSPD--GRYLASGSFDKCVHIWNTQTGALVHSYRGTGGIFE-VCWNA 493
Query: 719 DGSLCASGGKDMXAMLWDL 775
G + D + DL
Sbjct: 494 AGDKVGASASDGSVCVLDL 512
>AK022956-1|BAB14331.1| 514|Homo sapiens protein ( Homo sapiens
cDNA FLJ12894 fis, clone NT2RP2004170, moderately
similar to Homo sapiens mRNA for transducin (beta) like
1 protein. ).
Length = 514
Score = 79.4 bits (187), Expect = 1e-14
Identities = 62/230 (26%), Positives = 102/230 (44%), Gaps = 8/230 (3%)
Frame = +2
Query: 131 LRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFI 310
L TL H G + + N K + ILS+ DKT I+W E P HS
Sbjct: 258 LASTLGQHKGPIFALKWNKK-GNFILSAGVDKTTIIWDAHTGEAKQQFPF-----HSAPA 311
Query: 311 SDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRD 490
DV S+ +A S S D + + L + + F+ HT +V ++ + + S S D
Sbjct: 312 LDVDWQSNNTFA-SCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDD 370
Query: 491 KTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPN-------HANPIIVSCGWDRTVKVWH 646
T+K+W+ + C + +Q H+ + +++SP +AN ++ S +D TV++W
Sbjct: 371 MTLKIWSMKQDNCVHDLQ--AHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWD 428
Query: 647 LTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
+ H + +V SPDG ASG D +W+ G +H
Sbjct: 429 VDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVH 478
Score = 60.1 bits (139), Expect = 9e-09
Identities = 57/229 (24%), Positives = 91/229 (39%), Gaps = 11/229 (4%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRL----------Y 292
LRGH V A NP D++ S S D T +W L+ + + G Q L
Sbjct: 165 LRGHESEVFICAWNP-VSDLLASGSGDSTARIWNLSENSTS-GSTQLVLRHCIREGGQDV 222
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI 472
+ ++ + +S+G +GS+D R+W G H + ++ ++ I
Sbjct: 223 PSNKDVTSLDWNSEGTLLATGSYDGFARIWT-KDGNLASTLGQHKGPIFALKWNKKGNFI 281
Query: 473 VSGSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 649
+S DKT +W+ E K Q HS V + N+ SC D + V L
Sbjct: 282 LSAGVDKTTIIWDAHTGEAKQ--QFPFHSAPALDVDWQSNNT---FASCSTDMCIHVCKL 336
Query: 650 TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
+ GH+ +N + P G+L AS DM +W + +H
Sbjct: 337 GQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVH 385
Score = 55.6 bits (128), Expect = 2e-07
Identities = 49/199 (24%), Positives = 83/199 (41%), Gaps = 10/199 (5%)
Frame = +2
Query: 209 SSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDL 388
S S D + V KL +D P K GH++ ++ + GN S S D TL++W +
Sbjct: 324 SCSTDMCIHVCKLGQDR-----PIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSM 378
Query: 389 AAGKTTRRFEDHTKDVLSVAFSVD---------NRQIVSGSRDKTIKLWNT-LAECKYTI 538
+ H K++ ++ +S N + S S D T++LW+ C +T+
Sbjct: 379 KQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTL 438
Query: 539 QDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSP 718
H + V V FSP+ + S +D+ V +W+ L ++ G G V +
Sbjct: 439 TK--HQEPVYSVAFSPD--GRYLASGSFDKCVHIWNTQTGALVHSYRGTGGIFE-VCWNA 493
Query: 719 DGSLCASGGKDMXAMLWDL 775
G + D + DL
Sbjct: 494 AGDKVGASASDGSVCVLDL 512
>AF332222-1|AAK13474.1| 522|Homo sapiens transducin beta-like 1
protein.
Length = 522
Score = 79.4 bits (187), Expect = 1e-14
Identities = 62/235 (26%), Positives = 104/235 (44%), Gaps = 8/235 (3%)
Frame = +2
Query: 116 SETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
+E L TL H G + + N K + +LS+ DKT I+W E P
Sbjct: 263 TENGNLASTLGQHKGPIFALKWNKK-GNYVLSAGVDKTTIIWDAHTGEAKQQFPF----- 316
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
HS DV ++ +A S S D + + L + F+ HT +V ++ + +
Sbjct: 317 HSAPALDVDWQNNMTFA-SCSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGMLLA 375
Query: 476 SGSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNH---ANP----IIVSCGWDRT 631
S S D T+K+W+ + C + +Q HS + +++SP +NP ++ S +D T
Sbjct: 376 SCSDDMTLKIWSMKQDACVHDLQ--AHSKEIYTIKWSPTGPATSNPNSSIMLASASFDST 433
Query: 632 VKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
V++W + + H + +V SPDG ASG D +W+ G +H
Sbjct: 434 VRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVH 488
Score = 47.2 bits (107), Expect = 7e-05
Identities = 26/107 (24%), Positives = 51/107 (47%)
Frame = +2
Query: 179 TNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGS 358
+NP M+ S+S D T+ +W + + G+ L H + V S DG Y SGS
Sbjct: 417 SNPNSSIMLASASFDSTVRLWDVEQ-----GVCTHTLMKHQEPVYSVAFSPDGKYLASGS 471
Query: 359 WDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTI 499
+DK + +W+ +G ++ T + V ++ ++ + + D ++
Sbjct: 472 FDKYVHIWNTQSGSLVHSYQG-TGGIFEVCWNARGDKVGASASDGSV 517
Score = 34.7 bits (76), Expect = 0.39
Identities = 28/133 (21%), Positives = 52/133 (39%), Gaps = 11/133 (8%)
Frame = +2
Query: 422 HTKDVLSVAFSVDNRQIVSGSRDKTIKLWN---------TLAECKYTIQDDGHS--DWVS 568
H +V A++ + + SGS D T ++WN T ++ I++ GH
Sbjct: 178 HESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKD 237
Query: 569 CVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGK 748
N ++ +D ++W N L H G + + + G+ S G
Sbjct: 238 VTSLDWNSDGTLLAMGSYDGFARIW-TENGNLASTLGQHKGPIFALKWNKKGNYVLSAGV 296
Query: 749 DMXAMLWDLNDGK 787
D ++WD + G+
Sbjct: 297 DKTTIIWDAHTGE 309
Score = 32.7 bits (71), Expect = 1.6
Identities = 31/133 (23%), Positives = 54/133 (40%), Gaps = 14/133 (10%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDL---AAGKTTRRFEDH----------- 424
L GH + + + SGS D T R+W+L + G +T+ H
Sbjct: 175 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 234
Query: 425 TKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPI 604
KDV S+ ++ D + GS D ++W T+ H + +++ N
Sbjct: 235 NKDVTSLDWNSDGTLLAMGSYDGFARIWTENGNLASTLGQ--HKGPIFALKW--NKKGNY 290
Query: 605 IVSCGWDRTVKVW 643
++S G D+T +W
Sbjct: 291 VLSAGVDKTTIIW 303
>AF332221-1|AAK13473.1| 522|Homo sapiens transducin beta-like 1
protein.
Length = 522
Score = 79.4 bits (187), Expect = 1e-14
Identities = 62/235 (26%), Positives = 104/235 (44%), Gaps = 8/235 (3%)
Frame = +2
Query: 116 SETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
+E L TL H G + + N K + +LS+ DKT I+W E P
Sbjct: 263 TENGNLASTLGQHKGPIFALKWNKK-GNYVLSAGVDKTTIIWDAHTGEAKQQFPF----- 316
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
HS DV ++ +A S S D + + L + F+ HT +V ++ + +
Sbjct: 317 HSAPALDVDWQNNMTFA-SCSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGMLLA 375
Query: 476 SGSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNH---ANP----IIVSCGWDRT 631
S S D T+K+W+ + C + +Q HS + +++SP +NP ++ S +D T
Sbjct: 376 SCSDDMTLKIWSMKQDACVHDLQ--AHSKEIYTIKWSPTGPATSNPNSSIMLASASFDST 433
Query: 632 VKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
V++W + + H + +V SPDG ASG D +W+ G +H
Sbjct: 434 VRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVH 488
Score = 47.2 bits (107), Expect = 7e-05
Identities = 26/107 (24%), Positives = 51/107 (47%)
Frame = +2
Query: 179 TNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGS 358
+NP M+ S+S D T+ +W + + G+ L H + V S DG Y SGS
Sbjct: 417 SNPNSSIMLASASFDSTVRLWDVEQ-----GVCTHTLMKHQEPVYSVAFSPDGKYLASGS 471
Query: 359 WDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTI 499
+DK + +W+ +G ++ T + V ++ ++ + + D ++
Sbjct: 472 FDKYVHIWNTQSGSLVHSYQG-TGGIFEVCWNARGDKVGASASDGSV 517
Score = 34.7 bits (76), Expect = 0.39
Identities = 28/133 (21%), Positives = 52/133 (39%), Gaps = 11/133 (8%)
Frame = +2
Query: 422 HTKDVLSVAFSVDNRQIVSGSRDKTIKLWN---------TLAECKYTIQDDGHS--DWVS 568
H +V A++ + + SGS D T ++WN T ++ I++ GH
Sbjct: 178 HESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKD 237
Query: 569 CVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGK 748
N ++ +D ++W N L H G + + + G+ S G
Sbjct: 238 VTSLDWNSDGTLLAMGSYDGFARIW-TENGNLASTLGQHKGPIFALKWNKKGNYVLSAGV 296
Query: 749 DMXAMLWDLNDGK 787
D ++WD + G+
Sbjct: 297 DKTTIIWDAHTGE 309
Score = 32.7 bits (71), Expect = 1.6
Identities = 31/133 (23%), Positives = 54/133 (40%), Gaps = 14/133 (10%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDL---AAGKTTRRFEDH----------- 424
L GH + + + SGS D T R+W+L + G +T+ H
Sbjct: 175 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 234
Query: 425 TKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPI 604
KDV S+ ++ D + GS D ++W T+ H + +++ N
Sbjct: 235 NKDVTSLDWNSDGTLLAMGSYDGFARIWTENGNLASTLGQ--HKGPIFALKW--NKKGNY 290
Query: 605 IVSCGWDRTVKVW 643
++S G D+T +W
Sbjct: 291 VLSAGVDKTTIIW 303
>AF332220-1|AAK13472.1| 522|Homo sapiens transducin beta-like 1
protein.
Length = 522
Score = 79.4 bits (187), Expect = 1e-14
Identities = 62/235 (26%), Positives = 104/235 (44%), Gaps = 8/235 (3%)
Frame = +2
Query: 116 SETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYG 295
+E L TL H G + + N K + +LS+ DKT I+W E P
Sbjct: 263 TENGNLASTLGQHKGPIFALKWNKK-GNYVLSAGVDKTTIIWDAHTGEAKQQFPF----- 316
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
HS DV ++ +A S S D + + L + F+ HT +V ++ + +
Sbjct: 317 HSAPALDVDWQNNMTFA-SCSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGMLLA 375
Query: 476 SGSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNH---ANP----IIVSCGWDRT 631
S S D T+K+W+ + C + +Q HS + +++SP +NP ++ S +D T
Sbjct: 376 SCSDDMTLKIWSMKQDACVHDLQ--AHSKEIYTIKWSPTGPATSNPNSSIMLASASFDST 433
Query: 632 VKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
V++W + + H + +V SPDG ASG D +W+ G +H
Sbjct: 434 VRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVH 488
Score = 47.2 bits (107), Expect = 7e-05
Identities = 26/107 (24%), Positives = 51/107 (47%)
Frame = +2
Query: 179 TNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGS 358
+NP M+ S+S D T+ +W + + G+ L H + V S DG Y SGS
Sbjct: 417 SNPNSSIMLASASFDSTVRLWDVEQ-----GVCTHTLMKHQEPVYSVAFSPDGKYLASGS 471
Query: 359 WDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTI 499
+DK + +W+ +G ++ T + V ++ ++ + + D ++
Sbjct: 472 FDKYVHIWNTQSGSLVHSYQG-TGGIFEVCWNARGDKVGASASDGSV 517
Score = 34.7 bits (76), Expect = 0.39
Identities = 28/133 (21%), Positives = 52/133 (39%), Gaps = 11/133 (8%)
Frame = +2
Query: 422 HTKDVLSVAFSVDNRQIVSGSRDKTIKLWN---------TLAECKYTIQDDGHS--DWVS 568
H +V A++ + + SGS D T ++WN T ++ I++ GH
Sbjct: 178 HESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKD 237
Query: 569 CVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGK 748
N ++ +D ++W N L H G + + + G+ S G
Sbjct: 238 VTSLDWNSDGTLLAMGSYDGFARIW-TENGNLASTLGQHKGPIFALKWNKKGNYVLSAGV 296
Query: 749 DMXAMLWDLNDGK 787
D ++WD + G+
Sbjct: 297 DKTTIIWDAHTGE 309
Score = 32.7 bits (71), Expect = 1.6
Identities = 31/133 (23%), Positives = 54/133 (40%), Gaps = 14/133 (10%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDL---AAGKTTRRFEDH----------- 424
L GH + + + SGS D T R+W+L + G +T+ H
Sbjct: 175 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 234
Query: 425 TKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPI 604
KDV S+ ++ D + GS D ++W T+ H + +++ N
Sbjct: 235 NKDVTSLDWNSDGTLLAMGSYDGFARIWTENGNLASTLGQ--HKGPIFALKW--NKKGNY 290
Query: 605 IVSCGWDRTVKVW 643
++S G D+T +W
Sbjct: 291 VLSAGVDKTTIIW 303
>AF314544-1|AAK00301.1| 514|Homo sapiens nuclear receptor
co-repressor/HDAC3 complex subunit TBLR1 protein.
Length = 514
Score = 79.4 bits (187), Expect = 1e-14
Identities = 62/230 (26%), Positives = 102/230 (44%), Gaps = 8/230 (3%)
Frame = +2
Query: 131 LRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFI 310
L TL H G + + N K + ILS+ DKT I+W E P HS
Sbjct: 258 LASTLGQHKGPIFALKWNKK-GNFILSAGVDKTTIIWDAHTGEAKQQFPF-----HSAPA 311
Query: 311 SDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRD 490
DV S+ +A S S D + + L + + F+ HT +V ++ + + S S D
Sbjct: 312 LDVDWQSNNTFA-SCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDD 370
Query: 491 KTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPN-------HANPIIVSCGWDRTVKVWH 646
T+K+W+ + C + +Q H+ + +++SP +AN ++ S +D TV++W
Sbjct: 371 MTLKIWSMKQDNCVHDLQ--AHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWD 428
Query: 647 LTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
+ H + +V SPDG ASG D +W+ G +H
Sbjct: 429 VDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVH 478
Score = 60.1 bits (139), Expect = 9e-09
Identities = 57/229 (24%), Positives = 91/229 (39%), Gaps = 11/229 (4%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRL----------Y 292
LRGH V A NP D++ S S D T +W L+ + + G Q L
Sbjct: 165 LRGHESEVFICAWNP-VSDLLASGSGDSTARIWNLSENSTS-GSTQLVLRHCIREGGQDV 222
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI 472
+ ++ + +S+G +GS+D R+W G H + ++ ++ I
Sbjct: 223 PSNKDVTSLDWNSEGTLLATGSYDGFARIWT-KDGNLASTLGQHKGPIFALKWNKKGNFI 281
Query: 473 VSGSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 649
+S DKT +W+ E K Q HS V + N+ SC D + V L
Sbjct: 282 LSAGVDKTTIIWDAHTGEAKQ--QFPFHSAPALDVDWQSNNT---FASCSTDMCIHVCKL 336
Query: 650 TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
+ GH+ +N + P G+L AS DM +W + +H
Sbjct: 337 GQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVH 385
Score = 55.6 bits (128), Expect = 2e-07
Identities = 49/199 (24%), Positives = 83/199 (41%), Gaps = 10/199 (5%)
Frame = +2
Query: 209 SSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDL 388
S S D + V KL +D P K GH++ ++ + GN S S D TL++W +
Sbjct: 324 SCSTDMCIHVCKLGQDR-----PIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSM 378
Query: 389 AAGKTTRRFEDHTKDVLSVAFSVD---------NRQIVSGSRDKTIKLWNT-LAECKYTI 538
+ H K++ ++ +S N + S S D T++LW+ C +T+
Sbjct: 379 KQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTL 438
Query: 539 QDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSP 718
H + V V FSP+ + S +D+ V +W+ L ++ G G V +
Sbjct: 439 TK--HQEPVYSVAFSPD--GRYLASGSFDKCVHIWNTQTGALVHSYRGTGGIFE-VCWNA 493
Query: 719 DGSLCASGGKDMXAMLWDL 775
G + D + DL
Sbjct: 494 AGDKVGASASDGSVCVLDL 512
>AF268193-1|AAG44736.1| 514|Homo sapiens IRA1 protein.
Length = 514
Score = 79.4 bits (187), Expect = 1e-14
Identities = 62/230 (26%), Positives = 102/230 (44%), Gaps = 8/230 (3%)
Frame = +2
Query: 131 LRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFI 310
L TL H G + + N K + ILS+ DKT I+W E P HS
Sbjct: 258 LASTLGQHKGPIFALKWNKK-GNFILSAGVDKTTIIWDAHTGEAKQQFPF-----HSAPA 311
Query: 311 SDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRD 490
DV S+ +A S S D + + L + + F+ HT +V ++ + + S S D
Sbjct: 312 LDVDWQSNNTFA-SCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDD 370
Query: 491 KTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPN-------HANPIIVSCGWDRTVKVWH 646
T+K+W+ + C + +Q H+ + +++SP +AN ++ S +D TV++W
Sbjct: 371 MTLKIWSMKQDNCVHDLQQ--HNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWD 428
Query: 647 LTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
+ H + +V SPDG ASG D +W+ G +H
Sbjct: 429 VDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVH 478
Score = 60.1 bits (139), Expect = 9e-09
Identities = 57/229 (24%), Positives = 91/229 (39%), Gaps = 11/229 (4%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRL----------Y 292
LRGH V A NP D++ S S D T +W L+ + + G Q L
Sbjct: 165 LRGHESEVFICAWNP-VSDLLASGSGDSTARIWNLSENSTS-GSTQLVLRHCIREGGQDV 222
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI 472
+ ++ + +S+G +GS+D R+W G H + ++ ++ I
Sbjct: 223 PSNKDVTSLDWNSEGTLLATGSYDGFARIWT-KDGNLASTLGQHKGPIFALKWNKKGNFI 281
Query: 473 VSGSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 649
+S DKT +W+ E K Q HS V + N+ SC D + V L
Sbjct: 282 LSAGVDKTTIIWDAHTGEAKQ--QFPFHSAPALDVDWQSNNT---FASCSTDMCIHVCKL 336
Query: 650 TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
+ GH+ +N + P G+L AS DM +W + +H
Sbjct: 337 GQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVH 385
Score = 56.4 bits (130), Expect = 1e-07
Identities = 49/199 (24%), Positives = 83/199 (41%), Gaps = 10/199 (5%)
Frame = +2
Query: 209 SSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDL 388
S S D + V KL +D P K GH++ ++ + GN S S D TL++W +
Sbjct: 324 SCSTDMCIHVCKLGQDR-----PIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSM 378
Query: 389 AAGKTTRRFEDHTKDVLSVAFSVD---------NRQIVSGSRDKTIKLWNT-LAECKYTI 538
+ H K++ ++ +S N + S S D T++LW+ C +T+
Sbjct: 379 KQDNCVHDLQQHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTL 438
Query: 539 QDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSP 718
H + V V FSP+ + S +D+ V +W+ L ++ G G V +
Sbjct: 439 TK--HQEPVYSVAFSPD--GRYLASGSFDKCVHIWNTQTGALVHSYRGTGGIFE-VCWNA 493
Query: 719 DGSLCASGGKDMXAMLWDL 775
G + D + DL
Sbjct: 494 AGDKVGASASDGSVCVLDL 512
>AB040882-1|BAA95973.2| 680|Homo sapiens KIAA1449 protein protein.
Length = 680
Score = 79.0 bits (186), Expect = 2e-14
Identities = 58/248 (23%), Positives = 109/248 (43%), Gaps = 8/248 (3%)
Frame = +2
Query: 56 TCYRT*RFRESSLFKPFSKMSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLI 235
TC R+++ + ++S ++ NG V + +P + + ++ RD +
Sbjct: 1 TCKMAAHHRQNTAGRRKVQVSYVIRDEVEKYNRNG-VNALQLDPAL-NRLFTAGRDSIIR 58
Query: 236 VWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRF 415
+W + + + + I + H+ +++D+VL +G +S S D T+++W+ G
Sbjct: 59 IWSVNQHKQDPYIAS--MEHHTDWVNDIVLCCNGKTLISASSDTTVKVWNAHKGFCMSTL 116
Query: 416 EDHTKDVLSVAFSVDNRQIVSGSRDKTIKLW--NTLA------ECKYTIQDDGHSDWVSC 571
H V ++A++ D + S D+ I LW NTL T G+ D S
Sbjct: 117 RTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKD--SI 174
Query: 572 VRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKD 751
+ N IIVS ++ ++VW C + GH+ + + ++ DG+ C SG D
Sbjct: 175 YSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSD 234
Query: 752 MXAMLWDL 775
LW L
Sbjct: 235 GTIRLWSL 242
Score = 66.1 bits (154), Expect = 1e-10
Identities = 49/184 (26%), Positives = 85/184 (46%), Gaps = 7/184 (3%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTR----DENNYGIPQKRLYGHSHF 307
TLR H +V +A K +++ S+ D+ + +W + +N + L G+
Sbjct: 115 TLRTHKDYVKALAY-AKDKELVASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDS 173
Query: 308 ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSR 487
I + ++ G +SGS +K LR+WD + + HT +V ++ + D Q +SGS
Sbjct: 174 IYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSS 233
Query: 488 DKTIKLWNTLAE---CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 658
D TI+LW+ + Y + D+G W V N A + S G DR + L N
Sbjct: 234 DGTIRLWSLGQQRCIATYRVHDEG--VWALQV----NDAFTHVYSGGRDRKIYCTDLRNP 287
Query: 659 KLKI 670
+++
Sbjct: 288 DIRV 291
Score = 53.6 bits (123), Expect = 8e-07
Identities = 33/108 (30%), Positives = 48/108 (44%), Gaps = 2/108 (1%)
Frame = +2
Query: 461 NRQIVSGSRDKTIKLW--NTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTV 634
NR +G RD I++W N + Y + H+DWV+ + N ++S D TV
Sbjct: 46 NRLFTAG-RDSIIRIWSVNQHKQDPYIASMEHHTDWVNDIVLCCN--GKTLISASSDTTV 102
Query: 635 KVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLN 778
KVW+ H Y+ + + D L AS G D LWD+N
Sbjct: 103 KVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVN 150
>Y14153-1|CAA74572.1| 569|Homo sapiens beta-transducin repeats
containing protein protein.
Length = 569
Score = 78.6 bits (185), Expect = 2e-14
Identities = 59/202 (29%), Positives = 96/202 (47%), Gaps = 3/202 (1%)
Frame = +2
Query: 188 KYPDM-ILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWD 364
+Y D I+S RD T+ +W D+N ++ L GH+ + + L D ++GS D
Sbjct: 274 QYDDQKIVSGLRDNTIKIW----DKNTLEC-KRILTGHTGSV--LCLQYDERVIITGSSD 326
Query: 365 KTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQD 544
T+R+WD+ G+ H + VL + F+ N +V+ S+D++I +W+ + T++
Sbjct: 327 STVRVWDVNTGEMLNTLIHHCEAVLHLRFN--NGMMVTCSKDRSIAVWDMASPTDITLRR 384
Query: 545 D--GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSP 718
GH V+ V F + IVS DRT+KVW+ + C+ GH +
Sbjct: 385 VLVGHRAAVNVVDFDDKY----IVSASGDRTIKVWNTSTCEFVRTLNGHK--RGIACLQY 438
Query: 719 DGSLCASGGKDMXAMLWDLNDG 784
L SG D LWD+ G
Sbjct: 439 RDRLVVSGSSDNTIRLWDIECG 460
Score = 68.9 bits (161), Expect = 2e-11
Identities = 58/186 (31%), Positives = 84/186 (45%), Gaps = 9/186 (4%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSH 304
+ LR L GH V + + KY I+S+S D+T+ VW + E + L GH
Sbjct: 380 ITLRRVLVGHRAAVNVVDFDDKY---IVSASGDRTIKVWNTSTCEF-----VRTLNGHKR 431
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGS 484
I+ L +SGS D T+RLWD+ G R E H + V + F DN++IVSG+
Sbjct: 432 GIA--CLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGA 487
Query: 485 RDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPI---------IVSCGWDRTVK 637
D IK+W+ +A D C+R H+ + IVS D T+
Sbjct: 488 YDGKIKVWDLVAAL-----DPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTIL 542
Query: 638 VWHLTN 655
+W N
Sbjct: 543 IWDFLN 548
Score = 60.9 bits (141), Expect = 5e-09
Identities = 45/154 (29%), Positives = 75/154 (48%), Gaps = 4/154 (2%)
Frame = +2
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
L D +SG D T+++WD + R HT VL + + D R I++GS D T++
Sbjct: 273 LQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQY--DERVIITGSSDSTVR 330
Query: 503 LWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL---TNCKLKI 670
+W+ E T+ H + V +RF+ N ++V+C DR++ VW + T+ L+
Sbjct: 331 VWDVNTGEMLNTLIH--HCEAVLHLRFN----NGMMVTCSKDRSIAVWDMASPTDITLRR 384
Query: 671 NHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+GH +N V + ASG D +W+
Sbjct: 385 VLVGHRAAVNVVDFDDKYIVSASG--DRTIKVWN 416
>BC027994-1|AAH27994.1| 605|Homo sapiens beta-transducin repeat
containing protein.
Length = 605
Score = 78.6 bits (185), Expect = 2e-14
Identities = 59/202 (29%), Positives = 96/202 (47%), Gaps = 3/202 (1%)
Frame = +2
Query: 188 KYPDM-ILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWD 364
+Y D I+S RD T+ +W D+N ++ L GH+ + + L D ++GS D
Sbjct: 310 QYDDQKIVSGLRDNTIKIW----DKNTLEC-KRILTGHTGSV--LCLQYDERVIITGSSD 362
Query: 365 KTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQD 544
T+R+WD+ G+ H + VL + F+ N +V+ S+D++I +W+ + T++
Sbjct: 363 STVRVWDVNTGEMLNTLIHHCEAVLHLRFN--NGMMVTCSKDRSIAVWDMASPTDITLRR 420
Query: 545 D--GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSP 718
GH V+ V F + IVS DRT+KVW+ + C+ GH +
Sbjct: 421 VLVGHRAAVNVVDFDDKY----IVSASGDRTIKVWNTSTCEFVRTLNGHK--RGIACLQY 474
Query: 719 DGSLCASGGKDMXAMLWDLNDG 784
L SG D LWD+ G
Sbjct: 475 RDRLVVSGSSDNTIRLWDIECG 496
Score = 68.9 bits (161), Expect = 2e-11
Identities = 58/186 (31%), Positives = 84/186 (45%), Gaps = 9/186 (4%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSH 304
+ LR L GH V + + KY I+S+S D+T+ VW + E + L GH
Sbjct: 416 ITLRRVLVGHRAAVNVVDFDDKY---IVSASGDRTIKVWNTSTCEF-----VRTLNGHKR 467
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGS 484
I+ L +SGS D T+RLWD+ G R E H + V + F DN++IVSG+
Sbjct: 468 GIA--CLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGA 523
Query: 485 RDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPI---------IVSCGWDRTVK 637
D IK+W+ +A D C+R H+ + IVS D T+
Sbjct: 524 YDGKIKVWDLVAAL-----DPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTIL 578
Query: 638 VWHLTN 655
+W N
Sbjct: 579 IWDFLN 584
Score = 60.9 bits (141), Expect = 5e-09
Identities = 45/154 (29%), Positives = 75/154 (48%), Gaps = 4/154 (2%)
Frame = +2
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
L D +SG D T+++WD + R HT VL + + D R I++GS D T++
Sbjct: 309 LQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQY--DERVIITGSSDSTVR 366
Query: 503 LWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL---TNCKLKI 670
+W+ E T+ H + V +RF+ N ++V+C DR++ VW + T+ L+
Sbjct: 367 VWDVNTGEMLNTLIH--HCEAVLHLRFN----NGMMVTCSKDRSIAVWDMASPTDITLRR 420
Query: 671 NHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+GH +N V + ASG D +W+
Sbjct: 421 VLVGHRAAVNVVDFDDKYIVSASG--DRTIKVWN 452
>BC026353-1|AAH26353.1| 677|Homo sapiens WD repeat domain 48
protein.
Length = 677
Score = 78.6 bits (185), Expect = 2e-14
Identities = 50/199 (25%), Positives = 90/199 (45%), Gaps = 8/199 (4%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLW 382
+ ++ RD + +W + + + + I + H+ +++D+VL +G +S S D T+++W
Sbjct: 45 LFTAGRDSIIRIWSVNQHKQDPYIAS--MEHHTDWVNDIVLCCNGKTLISASSDTTVKVW 102
Query: 383 DLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLW--NTLA------ECKYTI 538
+ G H V ++A++ D + S D+ I LW NTL T
Sbjct: 103 NAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVTTS 162
Query: 539 QDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSP 718
G+ D S + N IIVS ++ ++VW C + GH+ + + ++
Sbjct: 163 SLSGNKD--SIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNR 220
Query: 719 DGSLCASGGKDMXAMLWDL 775
DG+ C SG D LW L
Sbjct: 221 DGTQCLSGSSDGTIRLWSL 239
Score = 66.1 bits (154), Expect = 1e-10
Identities = 49/184 (26%), Positives = 85/184 (46%), Gaps = 7/184 (3%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTR----DENNYGIPQKRLYGHSHF 307
TLR H +V +A K +++ S+ D+ + +W + +N + L G+
Sbjct: 112 TLRTHKDYVKALAY-AKDKELVASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDS 170
Query: 308 ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSR 487
I + ++ G +SGS +K LR+WD + + HT +V ++ + D Q +SGS
Sbjct: 171 IYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSS 230
Query: 488 DKTIKLWNTLAE---CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 658
D TI+LW+ + Y + D+G W V N A + S G DR + L N
Sbjct: 231 DGTIRLWSLGQQRCIATYRVHDEG--VWALQV----NDAFTHVYSGGRDRKIYCTDLRNP 284
Query: 659 KLKI 670
+++
Sbjct: 285 DIRV 288
Score = 53.6 bits (123), Expect = 8e-07
Identities = 33/108 (30%), Positives = 48/108 (44%), Gaps = 2/108 (1%)
Frame = +2
Query: 461 NRQIVSGSRDKTIKLW--NTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTV 634
NR +G RD I++W N + Y + H+DWV+ + N ++S D TV
Sbjct: 43 NRLFTAG-RDSIIRIWSVNQHKQDPYIASMEHHTDWVNDIVLCCN--GKTLISASSDTTV 99
Query: 635 KVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLN 778
KVW+ H Y+ + + D L AS G D LWD+N
Sbjct: 100 KVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVN 147
>AL627424-18|CAI41043.1| 569|Homo sapiens beta-transducin repeat
containing protein.
Length = 569
Score = 78.6 bits (185), Expect = 2e-14
Identities = 59/202 (29%), Positives = 96/202 (47%), Gaps = 3/202 (1%)
Frame = +2
Query: 188 KYPDM-ILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWD 364
+Y D I+S RD T+ +W D+N ++ L GH+ + + L D ++GS D
Sbjct: 274 QYDDQKIVSGLRDNTIKIW----DKNTLEC-KRILTGHTGSV--LCLQYDERVIITGSSD 326
Query: 365 KTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQD 544
T+R+WD+ G+ H + VL + F+ N +V+ S+D++I +W+ + T++
Sbjct: 327 STVRVWDVNTGEMLNTLIHHCEAVLHLRFN--NGMMVTCSKDRSIAVWDMASPTDITLRR 384
Query: 545 D--GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSP 718
GH V+ V F + IVS DRT+KVW+ + C+ GH +
Sbjct: 385 VLVGHRAAVNVVDFDDKY----IVSASGDRTIKVWNTSTCEFVRTLNGHK--RGIACLQY 438
Query: 719 DGSLCASGGKDMXAMLWDLNDG 784
L SG D LWD+ G
Sbjct: 439 RDRLVVSGSSDNTIRLWDIECG 460
Score = 68.9 bits (161), Expect = 2e-11
Identities = 58/186 (31%), Positives = 84/186 (45%), Gaps = 9/186 (4%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSH 304
+ LR L GH V + + KY I+S+S D+T+ VW + E + L GH
Sbjct: 380 ITLRRVLVGHRAAVNVVDFDDKY---IVSASGDRTIKVWNTSTCEF-----VRTLNGHKR 431
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGS 484
I+ L +SGS D T+RLWD+ G R E H + V + F DN++IVSG+
Sbjct: 432 GIA--CLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGA 487
Query: 485 RDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPI---------IVSCGWDRTVK 637
D IK+W+ +A D C+R H+ + IVS D T+
Sbjct: 488 YDGKIKVWDLVAAL-----DPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTIL 542
Query: 638 VWHLTN 655
+W N
Sbjct: 543 IWDFLN 548
Score = 60.9 bits (141), Expect = 5e-09
Identities = 45/154 (29%), Positives = 75/154 (48%), Gaps = 4/154 (2%)
Frame = +2
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
L D +SG D T+++WD + R HT VL + + D R I++GS D T++
Sbjct: 273 LQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQY--DERVIITGSSDSTVR 330
Query: 503 LWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL---TNCKLKI 670
+W+ E T+ H + V +RF+ N ++V+C DR++ VW + T+ L+
Sbjct: 331 VWDVNTGEMLNTLIH--HCEAVLHLRFN----NGMMVTCSKDRSIAVWDMASPTDITLRR 384
Query: 671 NHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+GH +N V + ASG D +W+
Sbjct: 385 VLVGHRAAVNVVDFDDKYIVSASG--DRTIKVWN 416
>AL627424-17|CAI41042.1| 605|Homo sapiens beta-transducin repeat
containing protein.
Length = 605
Score = 78.6 bits (185), Expect = 2e-14
Identities = 59/202 (29%), Positives = 96/202 (47%), Gaps = 3/202 (1%)
Frame = +2
Query: 188 KYPDM-ILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWD 364
+Y D I+S RD T+ +W D+N ++ L GH+ + + L D ++GS D
Sbjct: 310 QYDDQKIVSGLRDNTIKIW----DKNTLEC-KRILTGHTGSV--LCLQYDERVIITGSSD 362
Query: 365 KTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQD 544
T+R+WD+ G+ H + VL + F+ N +V+ S+D++I +W+ + T++
Sbjct: 363 STVRVWDVNTGEMLNTLIHHCEAVLHLRFN--NGMMVTCSKDRSIAVWDMASPTDITLRR 420
Query: 545 D--GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSP 718
GH V+ V F + IVS DRT+KVW+ + C+ GH +
Sbjct: 421 VLVGHRAAVNVVDFDDKY----IVSASGDRTIKVWNTSTCEFVRTLNGHK--RGIACLQY 474
Query: 719 DGSLCASGGKDMXAMLWDLNDG 784
L SG D LWD+ G
Sbjct: 475 RDRLVVSGSSDNTIRLWDIECG 496
Score = 68.9 bits (161), Expect = 2e-11
Identities = 58/186 (31%), Positives = 84/186 (45%), Gaps = 9/186 (4%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSH 304
+ LR L GH V + + KY I+S+S D+T+ VW + E + L GH
Sbjct: 416 ITLRRVLVGHRAAVNVVDFDDKY---IVSASGDRTIKVWNTSTCEF-----VRTLNGHKR 467
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGS 484
I+ L +SGS D T+RLWD+ G R E H + V + F DN++IVSG+
Sbjct: 468 GIA--CLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGA 523
Query: 485 RDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPI---------IVSCGWDRTVK 637
D IK+W+ +A D C+R H+ + IVS D T+
Sbjct: 524 YDGKIKVWDLVAAL-----DPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTIL 578
Query: 638 VWHLTN 655
+W N
Sbjct: 579 IWDFLN 584
Score = 60.9 bits (141), Expect = 5e-09
Identities = 45/154 (29%), Positives = 75/154 (48%), Gaps = 4/154 (2%)
Frame = +2
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
L D +SG D T+++WD + R HT VL + + D R I++GS D T++
Sbjct: 309 LQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQY--DERVIITGSSDSTVR 366
Query: 503 LWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL---TNCKLKI 670
+W+ E T+ H + V +RF+ N ++V+C DR++ VW + T+ L+
Sbjct: 367 VWDVNTGEMLNTLIH--HCEAVLHLRFN----NGMMVTCSKDRSIAVWDMASPTDITLRR 420
Query: 671 NHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+GH +N V + ASG D +W+
Sbjct: 421 VLVGHRAAVNVVDFDDKYIVSASG--DRTIKVWN 452
>AL445463-3|CAI12964.1| 569|Homo sapiens beta-transducin repeat
containing protein.
Length = 569
Score = 78.6 bits (185), Expect = 2e-14
Identities = 59/202 (29%), Positives = 96/202 (47%), Gaps = 3/202 (1%)
Frame = +2
Query: 188 KYPDM-ILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWD 364
+Y D I+S RD T+ +W D+N ++ L GH+ + + L D ++GS D
Sbjct: 274 QYDDQKIVSGLRDNTIKIW----DKNTLEC-KRILTGHTGSV--LCLQYDERVIITGSSD 326
Query: 365 KTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQD 544
T+R+WD+ G+ H + VL + F+ N +V+ S+D++I +W+ + T++
Sbjct: 327 STVRVWDVNTGEMLNTLIHHCEAVLHLRFN--NGMMVTCSKDRSIAVWDMASPTDITLRR 384
Query: 545 D--GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSP 718
GH V+ V F + IVS DRT+KVW+ + C+ GH +
Sbjct: 385 VLVGHRAAVNVVDFDDKY----IVSASGDRTIKVWNTSTCEFVRTLNGHK--RGIACLQY 438
Query: 719 DGSLCASGGKDMXAMLWDLNDG 784
L SG D LWD+ G
Sbjct: 439 RDRLVVSGSSDNTIRLWDIECG 460
Score = 68.9 bits (161), Expect = 2e-11
Identities = 58/186 (31%), Positives = 84/186 (45%), Gaps = 9/186 (4%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSH 304
+ LR L GH V + + KY I+S+S D+T+ VW + E + L GH
Sbjct: 380 ITLRRVLVGHRAAVNVVDFDDKY---IVSASGDRTIKVWNTSTCEF-----VRTLNGHKR 431
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGS 484
I+ L +SGS D T+RLWD+ G R E H + V + F DN++IVSG+
Sbjct: 432 GIA--CLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGA 487
Query: 485 RDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPI---------IVSCGWDRTVK 637
D IK+W+ +A D C+R H+ + IVS D T+
Sbjct: 488 YDGKIKVWDLVAAL-----DPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTIL 542
Query: 638 VWHLTN 655
+W N
Sbjct: 543 IWDFLN 548
Score = 60.9 bits (141), Expect = 5e-09
Identities = 45/154 (29%), Positives = 75/154 (48%), Gaps = 4/154 (2%)
Frame = +2
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
L D +SG D T+++WD + R HT VL + + D R I++GS D T++
Sbjct: 273 LQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQY--DERVIITGSSDSTVR 330
Query: 503 LWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL---TNCKLKI 670
+W+ E T+ H + V +RF+ N ++V+C DR++ VW + T+ L+
Sbjct: 331 VWDVNTGEMLNTLIH--HCEAVLHLRFN----NGMMVTCSKDRSIAVWDMASPTDITLRR 384
Query: 671 NHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+GH +N V + ASG D +W+
Sbjct: 385 VLVGHRAAVNVVDFDDKYIVSASG--DRTIKVWN 416
>AL445463-2|CAI12963.1| 605|Homo sapiens beta-transducin repeat
containing protein.
Length = 605
Score = 78.6 bits (185), Expect = 2e-14
Identities = 59/202 (29%), Positives = 96/202 (47%), Gaps = 3/202 (1%)
Frame = +2
Query: 188 KYPDM-ILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWD 364
+Y D I+S RD T+ +W D+N ++ L GH+ + + L D ++GS D
Sbjct: 310 QYDDQKIVSGLRDNTIKIW----DKNTLEC-KRILTGHTGSV--LCLQYDERVIITGSSD 362
Query: 365 KTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQD 544
T+R+WD+ G+ H + VL + F+ N +V+ S+D++I +W+ + T++
Sbjct: 363 STVRVWDVNTGEMLNTLIHHCEAVLHLRFN--NGMMVTCSKDRSIAVWDMASPTDITLRR 420
Query: 545 D--GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSP 718
GH V+ V F + IVS DRT+KVW+ + C+ GH +
Sbjct: 421 VLVGHRAAVNVVDFDDKY----IVSASGDRTIKVWNTSTCEFVRTLNGHK--RGIACLQY 474
Query: 719 DGSLCASGGKDMXAMLWDLNDG 784
L SG D LWD+ G
Sbjct: 475 RDRLVVSGSSDNTIRLWDIECG 496
Score = 68.9 bits (161), Expect = 2e-11
Identities = 58/186 (31%), Positives = 84/186 (45%), Gaps = 9/186 (4%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSH 304
+ LR L GH V + + KY I+S+S D+T+ VW + E + L GH
Sbjct: 416 ITLRRVLVGHRAAVNVVDFDDKY---IVSASGDRTIKVWNTSTCEF-----VRTLNGHKR 467
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGS 484
I+ L +SGS D T+RLWD+ G R E H + V + F DN++IVSG+
Sbjct: 468 GIA--CLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGA 523
Query: 485 RDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPI---------IVSCGWDRTVK 637
D IK+W+ +A D C+R H+ + IVS D T+
Sbjct: 524 YDGKIKVWDLVAAL-----DPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTIL 578
Query: 638 VWHLTN 655
+W N
Sbjct: 579 IWDFLN 584
Score = 60.9 bits (141), Expect = 5e-09
Identities = 45/154 (29%), Positives = 75/154 (48%), Gaps = 4/154 (2%)
Frame = +2
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
L D +SG D T+++WD + R HT VL + + D R I++GS D T++
Sbjct: 309 LQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQY--DERVIITGSSDSTVR 366
Query: 503 LWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL---TNCKLKI 670
+W+ E T+ H + V +RF+ N ++V+C DR++ VW + T+ L+
Sbjct: 367 VWDVNTGEMLNTLIH--HCEAVLHLRFN----NGMMVTCSKDRSIAVWDMASPTDITLRR 420
Query: 671 NHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+GH +N V + ASG D +W+
Sbjct: 421 VLVGHRAAVNVVDFDDKYIVSASG--DRTIKVWN 452
>AL133387-2|CAH70019.1| 569|Homo sapiens beta-transducin repeat
containing protein.
Length = 569
Score = 78.6 bits (185), Expect = 2e-14
Identities = 59/202 (29%), Positives = 96/202 (47%), Gaps = 3/202 (1%)
Frame = +2
Query: 188 KYPDM-ILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWD 364
+Y D I+S RD T+ +W D+N ++ L GH+ + + L D ++GS D
Sbjct: 274 QYDDQKIVSGLRDNTIKIW----DKNTLEC-KRILTGHTGSV--LCLQYDERVIITGSSD 326
Query: 365 KTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQD 544
T+R+WD+ G+ H + VL + F+ N +V+ S+D++I +W+ + T++
Sbjct: 327 STVRVWDVNTGEMLNTLIHHCEAVLHLRFN--NGMMVTCSKDRSIAVWDMASPTDITLRR 384
Query: 545 D--GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSP 718
GH V+ V F + IVS DRT+KVW+ + C+ GH +
Sbjct: 385 VLVGHRAAVNVVDFDDKY----IVSASGDRTIKVWNTSTCEFVRTLNGHK--RGIACLQY 438
Query: 719 DGSLCASGGKDMXAMLWDLNDG 784
L SG D LWD+ G
Sbjct: 439 RDRLVVSGSSDNTIRLWDIECG 460
Score = 68.9 bits (161), Expect = 2e-11
Identities = 58/186 (31%), Positives = 84/186 (45%), Gaps = 9/186 (4%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSH 304
+ LR L GH V + + KY I+S+S D+T+ VW + E + L GH
Sbjct: 380 ITLRRVLVGHRAAVNVVDFDDKY---IVSASGDRTIKVWNTSTCEF-----VRTLNGHKR 431
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGS 484
I+ L +SGS D T+RLWD+ G R E H + V + F DN++IVSG+
Sbjct: 432 GIA--CLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGA 487
Query: 485 RDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPI---------IVSCGWDRTVK 637
D IK+W+ +A D C+R H+ + IVS D T+
Sbjct: 488 YDGKIKVWDLVAAL-----DPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTIL 542
Query: 638 VWHLTN 655
+W N
Sbjct: 543 IWDFLN 548
Score = 60.9 bits (141), Expect = 5e-09
Identities = 45/154 (29%), Positives = 75/154 (48%), Gaps = 4/154 (2%)
Frame = +2
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
L D +SG D T+++WD + R HT VL + + D R I++GS D T++
Sbjct: 273 LQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQY--DERVIITGSSDSTVR 330
Query: 503 LWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL---TNCKLKI 670
+W+ E T+ H + V +RF+ N ++V+C DR++ VW + T+ L+
Sbjct: 331 VWDVNTGEMLNTLIH--HCEAVLHLRFN----NGMMVTCSKDRSIAVWDMASPTDITLRR 384
Query: 671 NHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+GH +N V + ASG D +W+
Sbjct: 385 VLVGHRAAVNVVDFDDKYIVSASG--DRTIKVWN 416
>AL133387-1|CAH70020.1| 605|Homo sapiens beta-transducin repeat
containing protein.
Length = 605
Score = 78.6 bits (185), Expect = 2e-14
Identities = 59/202 (29%), Positives = 96/202 (47%), Gaps = 3/202 (1%)
Frame = +2
Query: 188 KYPDM-ILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWD 364
+Y D I+S RD T+ +W D+N ++ L GH+ + + L D ++GS D
Sbjct: 310 QYDDQKIVSGLRDNTIKIW----DKNTLEC-KRILTGHTGSV--LCLQYDERVIITGSSD 362
Query: 365 KTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQD 544
T+R+WD+ G+ H + VL + F+ N +V+ S+D++I +W+ + T++
Sbjct: 363 STVRVWDVNTGEMLNTLIHHCEAVLHLRFN--NGMMVTCSKDRSIAVWDMASPTDITLRR 420
Query: 545 D--GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSP 718
GH V+ V F + IVS DRT+KVW+ + C+ GH +
Sbjct: 421 VLVGHRAAVNVVDFDDKY----IVSASGDRTIKVWNTSTCEFVRTLNGHK--RGIACLQY 474
Query: 719 DGSLCASGGKDMXAMLWDLNDG 784
L SG D LWD+ G
Sbjct: 475 RDRLVVSGSSDNTIRLWDIECG 496
Score = 68.9 bits (161), Expect = 2e-11
Identities = 58/186 (31%), Positives = 84/186 (45%), Gaps = 9/186 (4%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSH 304
+ LR L GH V + + KY I+S+S D+T+ VW + E + L GH
Sbjct: 416 ITLRRVLVGHRAAVNVVDFDDKY---IVSASGDRTIKVWNTSTCEF-----VRTLNGHKR 467
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGS 484
I+ L +SGS D T+RLWD+ G R E H + V + F DN++IVSG+
Sbjct: 468 GIA--CLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGA 523
Query: 485 RDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPI---------IVSCGWDRTVK 637
D IK+W+ +A D C+R H+ + IVS D T+
Sbjct: 524 YDGKIKVWDLVAAL-----DPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTIL 578
Query: 638 VWHLTN 655
+W N
Sbjct: 579 IWDFLN 584
Score = 60.9 bits (141), Expect = 5e-09
Identities = 45/154 (29%), Positives = 75/154 (48%), Gaps = 4/154 (2%)
Frame = +2
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
L D +SG D T+++WD + R HT VL + + D R I++GS D T++
Sbjct: 309 LQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQY--DERVIITGSSDSTVR 366
Query: 503 LWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL---TNCKLKI 670
+W+ E T+ H + V +RF+ N ++V+C DR++ VW + T+ L+
Sbjct: 367 VWDVNTGEMLNTLIH--HCEAVLHLRFN----NGMMVTCSKDRSIAVWDMASPTDITLRR 420
Query: 671 NHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+GH +N V + ASG D +W+
Sbjct: 421 VLVGHRAAVNVVDFDDKYIVSASG--DRTIKVWN 452
>AF468833-1|AAL78650.1| 677|Homo sapiens WD repeat endosomal
protein protein.
Length = 677
Score = 78.6 bits (185), Expect = 2e-14
Identities = 50/199 (25%), Positives = 90/199 (45%), Gaps = 8/199 (4%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLW 382
+ ++ RD + +W + + + + I + H+ +++D+VL +G +S S D T+++W
Sbjct: 45 LFTAGRDSIIRIWSVNQHKQDPYIAS--MEHHTDWVNDIVLCCNGKTLISASSDTTVKVW 102
Query: 383 DLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLW--NTLA------ECKYTI 538
+ G H V ++A++ D + S D+ I LW NTL T
Sbjct: 103 NAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVTTS 162
Query: 539 QDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSP 718
G+ D S + N IIVS ++ ++VW C + GH+ + + ++
Sbjct: 163 SLSGNKD--SIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNR 220
Query: 719 DGSLCASGGKDMXAMLWDL 775
DG+ C SG D LW L
Sbjct: 221 DGTQCLSGSSDGTIRLWSL 239
Score = 66.1 bits (154), Expect = 1e-10
Identities = 49/184 (26%), Positives = 85/184 (46%), Gaps = 7/184 (3%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTR----DENNYGIPQKRLYGHSHF 307
TLR H +V +A K +++ S+ D+ + +W + +N + L G+
Sbjct: 112 TLRTHKDYVKALAY-AKDKELVASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDS 170
Query: 308 ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSR 487
I + ++ G +SGS +K LR+WD + + HT +V ++ + D Q +SGS
Sbjct: 171 IYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSS 230
Query: 488 DKTIKLWNTLAE---CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 658
D TI+LW+ + Y + D+G W V N A + S G DR + L N
Sbjct: 231 DGTIRLWSLGQQRCIATYRVHDEG--VWALQV----NDAFTHVYSGGRDRKIYCTDLRNP 284
Query: 659 KLKI 670
+++
Sbjct: 285 DIRV 288
Score = 53.6 bits (123), Expect = 8e-07
Identities = 33/108 (30%), Positives = 48/108 (44%), Gaps = 2/108 (1%)
Frame = +2
Query: 461 NRQIVSGSRDKTIKLW--NTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTV 634
NR +G RD I++W N + Y + H+DWV+ + N ++S D TV
Sbjct: 43 NRLFTAG-RDSIIRIWSVNQHKQDPYIASMEHHTDWVNDIVLCCN--GKTLISASSDTTV 99
Query: 635 KVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLN 778
KVW+ H Y+ + + D L AS G D LWD+N
Sbjct: 100 KVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVN 147
>AF129530-1|AAF04464.1| 569|Homo sapiens F-box protein Fbw1A
protein.
Length = 569
Score = 78.6 bits (185), Expect = 2e-14
Identities = 59/202 (29%), Positives = 96/202 (47%), Gaps = 3/202 (1%)
Frame = +2
Query: 188 KYPDM-ILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWD 364
+Y D I+S RD T+ +W D+N ++ L GH+ + + L D ++GS D
Sbjct: 274 QYDDQKIVSGLRDNTIKIW----DKNTLEC-KRILTGHTGSV--LCLQYDERVIITGSSD 326
Query: 365 KTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQD 544
T+R+WD+ G+ H + VL + F+ N +V+ S+D++I +W+ + T++
Sbjct: 327 STVRVWDVNTGEMLNTLIHHCEAVLHLRFN--NGMMVTCSKDRSIAVWDMASPTDITLRR 384
Query: 545 D--GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSP 718
GH V+ V F + IVS DRT+KVW+ + C+ GH +
Sbjct: 385 VLVGHRAAVNVVDFDDKY----IVSASGDRTIKVWNTSTCEFVRTLNGHK--RGIACLQY 438
Query: 719 DGSLCASGGKDMXAMLWDLNDG 784
L SG D LWD+ G
Sbjct: 439 RDRLVVSGSSDNTIRLWDIECG 460
Score = 68.9 bits (161), Expect = 2e-11
Identities = 58/186 (31%), Positives = 84/186 (45%), Gaps = 9/186 (4%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSH 304
+ LR L GH V + + KY I+S+S D+T+ VW + E + L GH
Sbjct: 380 ITLRRVLVGHRAAVNVVDFDDKY---IVSASGDRTIKVWNTSTCEF-----VRTLNGHKR 431
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGS 484
I+ L +SGS D T+RLWD+ G R E H + V + F DN++IVSG+
Sbjct: 432 GIA--CLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGA 487
Query: 485 RDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPI---------IVSCGWDRTVK 637
D IK+W+ +A D C+R H+ + IVS D T+
Sbjct: 488 YDGKIKVWDLVAAL-----DPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTIL 542
Query: 638 VWHLTN 655
+W N
Sbjct: 543 IWDFLN 548
Score = 60.9 bits (141), Expect = 5e-09
Identities = 45/154 (29%), Positives = 75/154 (48%), Gaps = 4/154 (2%)
Frame = +2
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
L D +SG D T+++WD + R HT VL + + D R I++GS D T++
Sbjct: 273 LQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQY--DERVIITGSSDSTVR 330
Query: 503 LWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL---TNCKLKI 670
+W+ E T+ H + V +RF+ N ++V+C DR++ VW + T+ L+
Sbjct: 331 VWDVNTGEMLNTLIH--HCEAVLHLRFN----NGMMVTCSKDRSIAVWDMASPTDITLRR 384
Query: 671 NHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+GH +N V + ASG D +W+
Sbjct: 385 VLVGHRAAVNVVDFDDKYIVSASG--DRTIKVWN 416
>AF101784-1|AAD08702.1| 605|Homo sapiens b-TRCP variant
E3RS-IkappaB protein.
Length = 605
Score = 78.6 bits (185), Expect = 2e-14
Identities = 59/202 (29%), Positives = 96/202 (47%), Gaps = 3/202 (1%)
Frame = +2
Query: 188 KYPDM-ILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWD 364
+Y D I+S RD T+ +W D+N ++ L GH+ + + L D ++GS D
Sbjct: 310 QYDDQKIVSGLRDNTIKIW----DKNTLEC-KRILTGHTGSV--LCLQYDERVIITGSSD 362
Query: 365 KTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQD 544
T+R+WD+ G+ H + VL + F+ N +V+ S+D++I +W+ + T++
Sbjct: 363 STVRVWDVNTGEMLNTLIHHCEAVLHLRFN--NGMMVTCSKDRSIAVWDMASPTDITLRR 420
Query: 545 D--GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSP 718
GH V+ V F + IVS DRT+KVW+ + C+ GH +
Sbjct: 421 VLVGHRAAVNVVDFDDKY----IVSASGDRTIKVWNTSTCEFVRTLNGHK--RGIACLQY 474
Query: 719 DGSLCASGGKDMXAMLWDLNDG 784
L SG D LWD+ G
Sbjct: 475 RDRLVVSGSSDNTIRLWDIECG 496
Score = 68.9 bits (161), Expect = 2e-11
Identities = 58/186 (31%), Positives = 84/186 (45%), Gaps = 9/186 (4%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSH 304
+ LR L GH V + + KY I+S+S D+T+ VW + E + L GH
Sbjct: 416 ITLRRVLVGHRAAVNVVDFDDKY---IVSASGDRTIKVWNTSTCEF-----VRTLNGHKR 467
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGS 484
I+ L +SGS D T+RLWD+ G R E H + V + F DN++IVSG+
Sbjct: 468 GIA--CLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGA 523
Query: 485 RDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPI---------IVSCGWDRTVK 637
D IK+W+ +A D C+R H+ + IVS D T+
Sbjct: 524 YDGKIKVWDLVAAL-----DPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTIL 578
Query: 638 VWHLTN 655
+W N
Sbjct: 579 IWDFLN 584
Score = 60.9 bits (141), Expect = 5e-09
Identities = 45/154 (29%), Positives = 75/154 (48%), Gaps = 4/154 (2%)
Frame = +2
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
L D +SG D T+++WD + R HT VL + + D R I++GS D T++
Sbjct: 309 LQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQY--DERVIITGSSDSTVR 366
Query: 503 LWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL---TNCKLKI 670
+W+ E T+ H + V +RF+ N ++V+C DR++ VW + T+ L+
Sbjct: 367 VWDVNTGEMLNTLIH--HCEAVLHLRFN----NGMMVTCSKDRSIAVWDMASPTDITLRR 420
Query: 671 NHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+GH +N V + ASG D +W+
Sbjct: 421 VLVGHRAAVNVVDFDDKYIVSASG--DRTIKVWN 452
>BC031227-1|AAH31227.2| 452|Homo sapiens WDR88 protein protein.
Length = 452
Score = 78.2 bits (184), Expect = 3e-14
Identities = 53/204 (25%), Positives = 96/204 (47%), Gaps = 10/204 (4%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSG-SWDKTLRL 379
++++S DKT+ W L + + + + FI S DG Y +SG D + +
Sbjct: 186 VIAASYDKTVRAWDLETGKLLWKVR------YDTFIVSCKFSPDGKYVVSGFDVDHGICI 239
Query: 380 WDLAAGKTTRRFEDH-TKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHS 556
D T +DH T+ + S F D++++ S S D+ IK+W+ ++ HS
Sbjct: 240 MDAENITTVSVIKDHHTRSITSCCFDPDSQRVASVSLDRCIKIWDVTSQATLLTITKAHS 299
Query: 557 DWVS--CVRFSPNHANPIIVSCGWDRTVKVWHL-----TNCKLKINHL-GHSGYLNTVTV 712
+ +S C FS + + + WD+ +K+W++ NC + + GH G +++
Sbjct: 300 NAISNCCFTFSGH----FLCTSSWDKNLKIWNVHTGEFRNCGACVTLMQGHEGSVSSCHF 355
Query: 713 SPDGSLCASGGKDMXAMLWDLNDG 784
+ D S SGG D +WD+ +G
Sbjct: 356 ARDSSFLISGGFDRTVAIWDVAEG 379
Score = 71.7 bits (168), Expect = 3e-12
Identities = 34/104 (32%), Positives = 59/104 (56%), Gaps = 1/104 (0%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKL-TRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRL 379
+ +SS DK L +W + T + N G + GH +S + D ++ +SG +D+T+ +
Sbjct: 314 LCTSSWDKNLKIWNVHTGEFRNCGACVTLMQGHEGSVSSCHFARDSSFLISGGFDRTVAI 373
Query: 380 WDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN 511
WD+A G + H V+ VA S + + I+S S+D+T++LWN
Sbjct: 374 WDVAEGYRKLSLKGHNDWVMDVAISNNKKWILSASKDRTMRLWN 417
Score = 68.1 bits (159), Expect = 3e-11
Identities = 40/168 (23%), Positives = 76/168 (45%), Gaps = 6/168 (3%)
Frame = +2
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRF-EDHTKDVLSVAFSVDNRQI 472
H+ I+ D S S D+ +++WD+ + T + H+ + + F+ +
Sbjct: 255 HTRSITSCCFDPDSQRVASVSLDRCIKIWDVTSQATLLTITKAHSNAISNCCFTFSGHFL 314
Query: 473 VSGSRDKTIKLWNT----LAECKYTIQ-DDGHSDWVSCVRFSPNHANPIIVSCGWDRTVK 637
+ S DK +K+WN C + GH VS F+ + + ++S G+DRTV
Sbjct: 315 CTSSWDKNLKIWNVHTGEFRNCGACVTLMQGHEGSVSSCHFARDSS--FLISGGFDRTVA 372
Query: 638 VWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLND 781
+W + K++ GH+ ++ V +S + S KD LW++ +
Sbjct: 373 IWDVAEGYRKLSLKGHNDWVMDVAISNNKKWILSASKDRTMRLWNIEE 420
Score = 66.9 bits (156), Expect = 8e-11
Identities = 48/170 (28%), Positives = 78/170 (45%), Gaps = 2/170 (1%)
Frame = +2
Query: 272 IPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTK-DVLSVA 448
IP K L GH H +S D LSGS+D T++LWD G R FE K V+ +
Sbjct: 119 IPFKILSGHEHAVSTCHFCVDDTKLLSGSYDCTVKLWDPVDGSVVRDFEHRPKAPVVECS 178
Query: 449 FSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR 628
+ D+ ++++ S DKT++ W+ L K + + VSC +FSP+ ++ D
Sbjct: 179 ITGDSSRVIAASYDKTVRAWD-LETGKLLWKVRYDTFIVSC-KFSPD-GKYVVSGFDVDH 235
Query: 629 TVKVWHLTN-CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
+ + N + + H+ + + PD AS D +WD+
Sbjct: 236 GICIMDAENITTVSVIKDHHTRSITSCCFDPDSQRVASVSLDRCIKIWDV 285
Score = 45.6 bits (103), Expect = 2e-04
Identities = 23/82 (28%), Positives = 45/82 (54%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
++GH G V+ + ++S D+T+ +W + G + L GH+ ++ DV
Sbjct: 343 MQGHEGSVSSCHF-ARDSSFLISGGFDRTVAIWDVAE-----GYRKLSLKGHNDWVMDVA 396
Query: 323 LSSDGNYALSGSWDKTLRLWDL 388
+S++ + LS S D+T+RLW++
Sbjct: 397 ISNNKKWILSASKDRTMRLWNI 418
Score = 35.9 bits (79), Expect = 0.17
Identities = 19/53 (35%), Positives = 30/53 (56%), Gaps = 1/53 (1%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTR-DENNYGIPQKRLYG 295
+L+GHN WV +A + ILS+S+D+T+ +W + DE I K+ G
Sbjct: 384 SLKGHNDWVMDVAIS-NNKKWILSASKDRTMRLWNIEEIDEIPLVIKYKKAVG 435
>M36429-1|AAA63264.1| 340|Homo sapiens protein ( Human transducin
beta-2 subunit mRNA, complete cds. ).
Length = 340
Score = 77.8 bits (183), Expect = 4e-14
Identities = 59/213 (27%), Positives = 95/213 (44%), Gaps = 3/213 (1%)
Frame = +2
Query: 155 NGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSD 334
+ WV A P + + D ++ L E N + + L GH+ ++S D
Sbjct: 97 SSWVMTCAYAPS-GNFVACGGLDNICSIYSLKTREGNVRV-SRELPGHTGYLSCCRFLDD 154
Query: 335 GNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNT 514
N ++ S D T LWD+ G+ T F H+ DV+S++ + D R VSG+ D +IKLW+
Sbjct: 155 -NQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDV 213
Query: 515 L-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK--LKINHLGH 685
+ C+ T GH ++ V F PN + D T +++ L + L +H
Sbjct: 214 RDSMCRQTF--IGHESDINAVAFFPN--GYAFTTGSDDATCRLFDLRADQELLMYSHDNI 269
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDG 784
+ +V S G L +G D +WD G
Sbjct: 270 ICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKG 302
Score = 75.4 bits (177), Expect = 2e-13
Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 4/227 (1%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSH 304
++ R TLRGH + + +++S+S+D LI+W + IP + S
Sbjct: 45 MRTRRTLRGHLAKIYAMHWGTD-SRLLVSASQDGKLIIWDSYTTNKVHAIPLR-----SS 98
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAG----KTTRRFEDHTKDVLSVAFSVDNRQI 472
++ + GN+ G D ++ L + +R HT LS +D+ QI
Sbjct: 99 WVMTCAYAPSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHT-GYLSCCRFLDDNQI 157
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
++ S D T LW+ + + T+ GHS V + +P+ + +C D ++K+W +
Sbjct: 158 ITSSGDTTCALWD-IETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGAC--DASIKLWDVR 214
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ + +GH +N V P+G +G D L+DL + L
Sbjct: 215 DSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQEL 261
Score = 68.1 bits (159), Expect = 3e-11
Identities = 50/211 (23%), Positives = 94/211 (44%), Gaps = 1/211 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH G+++ + I++SS D T +W + + G GHS + +
Sbjct: 139 LPGHTGYLS--CCRFLDDNQIITSSGDTTCALWDIETGQQTVGFA-----GHSGDVMSLS 191
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
L+ DG +SG+ D +++LWD+ + F H D+ +VAF + +GS D T +
Sbjct: 192 LAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCR 251
Query: 503 LWNTLAECKYTIQD-DGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
L++ A+ + + D ++ V FS + ++++ D +W
Sbjct: 252 LFDLRADQELLMYSHDNIICGITSVAFS--RSGRLLLAGYDDFNCNIWDAMKGDRAGVLA 309
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
GH ++ + V+ DG A+G D +W+
Sbjct: 310 GHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>M16538-1|AAA35922.1| 340|Homo sapiens protein ( Human
signal-transducing guanine nucleotide-binding regulatory
(G) protein beta subunit mRNA, complete cds. ).
Length = 340
Score = 77.8 bits (183), Expect = 4e-14
Identities = 56/227 (24%), Positives = 100/227 (44%), Gaps = 4/227 (1%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSH 304
++ R TLRGH + + +++S+S+D LI+W + IP + S
Sbjct: 45 MRTRRTLRGHLAKIYAMHWGTD-SRLLVSASQDGKLIIWDSYTTNKVHAIPLR-----SS 98
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAG----KTTRRFEDHTKDVLSVAFSVDNRQI 472
++ + GN+ G D ++ L + +R HT LS +D+ QI
Sbjct: 99 WVMTCAYAXSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHT-GYLSCCRFLDDNQI 157
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
++ S D T LW+ + + T+ GHS V + +PN + +C D ++K+W +
Sbjct: 158 ITSSGDTTCALWD-IETGQQTVGFAGHSGDVMSLSLAPNGRTFVSGAC--DASIKLWDVR 214
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ + +GH +N V P+G +G D L+DL + L
Sbjct: 215 DSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQEL 261
Score = 72.9 bits (171), Expect = 1e-12
Identities = 54/191 (28%), Positives = 88/191 (46%), Gaps = 3/191 (1%)
Frame = +2
Query: 221 DKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGK 400
D ++ L E N + + L GH+ ++S D N ++ S D T LWD+ G+
Sbjct: 118 DNICSIYSLKTREGNVRV-SRELPGHTGYLSCCRFLDD-NQIITSSGDTTCALWDIETGQ 175
Query: 401 TTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTL-AECKYTIQDDGHSDWVSCVR 577
T F H+ DV+S++ + + R VSG+ D +IKLW+ + C+ T GH ++ V
Sbjct: 176 QTVGFAGHSGDVMSLSLAPNGRTFVSGACDASIKLWDVRDSMCRQTF--IGHESDINAVA 233
Query: 578 FSPNHANPIIVSCGWDRTVKVWHLTNCK--LKINHLGHSGYLNTVTVSPDGSLCASGGKD 751
F PN + D T +++ L + L +H + +V S G L +G D
Sbjct: 234 FFPN--GYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDD 291
Query: 752 MXAMLWDLNDG 784
+WD G
Sbjct: 292 FNCNIWDAMKG 302
Score = 66.1 bits (154), Expect = 1e-10
Identities = 49/211 (23%), Positives = 94/211 (44%), Gaps = 1/211 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH G+++ + I++SS D T +W + + G GHS + +
Sbjct: 139 LPGHTGYLS--CCRFLDDNQIITSSGDTTCALWDIETGQQTVGFA-----GHSGDVMSLS 191
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
L+ +G +SG+ D +++LWD+ + F H D+ +VAF + +GS D T +
Sbjct: 192 LAPNGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCR 251
Query: 503 LWNTLAECKYTIQD-DGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
L++ A+ + + D ++ V FS + ++++ D +W
Sbjct: 252 LFDLRADQELLMYSHDNIICGITSVAFS--RSGRLLLAGYDDFNCNIWDAMKGDRAGVLA 309
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
GH ++ + V+ DG A+G D +W+
Sbjct: 310 GHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>M16514-1|AAA03179.1| 340|Homo sapiens GNB2 protein.
Length = 340
Score = 77.8 bits (183), Expect = 4e-14
Identities = 59/213 (27%), Positives = 95/213 (44%), Gaps = 3/213 (1%)
Frame = +2
Query: 155 NGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSD 334
+ WV A P + + D ++ L E N + + L GH+ ++S D
Sbjct: 97 SSWVMTCAYAPS-GNFVACGGLDNICSIYSLKTREGNVRV-SRELPGHTGYLSCCRFLDD 154
Query: 335 GNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNT 514
N ++ S D T LWD+ G+ T F H+ DV+S++ + D R VSG+ D +IKLW+
Sbjct: 155 -NQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDV 213
Query: 515 L-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK--LKINHLGH 685
+ C+ T GH ++ V F PN + D T +++ L + L +H
Sbjct: 214 RDSMCRQTF--IGHESDINAVAFFPN--GYAFTTGSDDATCRLFDLRADQELLMYSHDNI 269
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDG 784
+ +V S G L +G D +WD G
Sbjct: 270 ICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKG 302
Score = 75.4 bits (177), Expect = 2e-13
Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 4/227 (1%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSH 304
++ R TLRGH + + +++S+S+D LI+W + IP + S
Sbjct: 45 MRTRRTLRGHLAKIYAMHWGTD-SRLLVSASQDGKLIIWDSYTTNKVHAIPLR-----SS 98
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAG----KTTRRFEDHTKDVLSVAFSVDNRQI 472
++ + GN+ G D ++ L + +R HT LS +D+ QI
Sbjct: 99 WVMTCAYAPSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHT-GYLSCCRFLDDNQI 157
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
++ S D T LW+ + + T+ GHS V + +P+ + +C D ++K+W +
Sbjct: 158 ITSSGDTTCALWD-IETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGAC--DASIKLWDVR 214
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ + +GH +N V P+G +G D L+DL + L
Sbjct: 215 DSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQEL 261
Score = 68.1 bits (159), Expect = 3e-11
Identities = 50/211 (23%), Positives = 94/211 (44%), Gaps = 1/211 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH G+++ + I++SS D T +W + + G GHS + +
Sbjct: 139 LPGHTGYLS--CCRFLDDNQIITSSGDTTCALWDIETGQQTVGFA-----GHSGDVMSLS 191
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
L+ DG +SG+ D +++LWD+ + F H D+ +VAF + +GS D T +
Sbjct: 192 LAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCR 251
Query: 503 LWNTLAECKYTIQD-DGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
L++ A+ + + D ++ V FS + ++++ D +W
Sbjct: 252 LFDLRADQELLMYSHDNIICGITSVAFS--RSGRLLLAGYDDFNCNIWDAMKGDRAGVLA 309
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
GH ++ + V+ DG A+G D +W+
Sbjct: 310 GHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>CR541729-1|CAG46530.1| 340|Homo sapiens GNB2 protein.
Length = 340
Score = 77.8 bits (183), Expect = 4e-14
Identities = 59/213 (27%), Positives = 95/213 (44%), Gaps = 3/213 (1%)
Frame = +2
Query: 155 NGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSD 334
+ WV A P + + D ++ L E N + + L GH+ ++S D
Sbjct: 97 SSWVMTCAYAPS-GNFVACGGLDNICSIYSLKTREGNVRV-SRELPGHTGYLSCCRFLDD 154
Query: 335 GNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNT 514
N ++ S D T LWD+ G+ T F H+ DV+S++ + D R VSG+ D +IKLW+
Sbjct: 155 -NQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDV 213
Query: 515 L-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK--LKINHLGH 685
+ C+ T GH ++ V F PN + D T +++ L + L +H
Sbjct: 214 RDSMCRQTF--IGHESDINAVAFFPN--GYAFTTGSDDATCRLFDLRADQELLMYSHDNI 269
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDG 784
+ +V S G L +G D +WD G
Sbjct: 270 ICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKG 302
Score = 75.4 bits (177), Expect = 2e-13
Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 4/227 (1%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSH 304
++ R TLRGH + + +++S+S+D LI+W + IP + S
Sbjct: 45 MRTRRTLRGHLAKIYAMHWGTD-SRLLVSASQDGKLIIWDSYTTNKVHAIPLR-----SS 98
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAG----KTTRRFEDHTKDVLSVAFSVDNRQI 472
++ + GN+ G D ++ L + +R HT LS +D+ QI
Sbjct: 99 WVMTCAYAPSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHT-GYLSCCRFLDDNQI 157
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
++ S D T LW+ + + T+ GHS V + +P+ + +C D ++K+W +
Sbjct: 158 ITSSGDTTCALWD-IETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGAC--DASIKLWDVR 214
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ + +GH +N V P+G +G D L+DL + L
Sbjct: 215 DSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQEL 261
Score = 68.1 bits (159), Expect = 3e-11
Identities = 50/211 (23%), Positives = 94/211 (44%), Gaps = 1/211 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH G+++ + I++SS D T +W + + G GHS + +
Sbjct: 139 LPGHTGYLS--CCRFLDDNQIITSSGDTTCALWDIETGQQTVGFA-----GHSGDVMSLS 191
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
L+ DG +SG+ D +++LWD+ + F H D+ +VAF + +GS D T +
Sbjct: 192 LAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCR 251
Query: 503 LWNTLAECKYTIQD-DGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
L++ A+ + + D ++ V FS + ++++ D +W
Sbjct: 252 LFDLRADQELLMYSHDNIICGITSVAFS--RSGRLLLAGYDDFNCNIWDAMKGDRAGVLA 309
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
GH ++ + V+ DG A+G D +W+
Sbjct: 310 GHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>BC107125-1|AAI07126.1| 248|Homo sapiens WDR86 protein protein.
Length = 248
Score = 77.8 bits (183), Expect = 4e-14
Identities = 54/193 (27%), Positives = 92/193 (47%), Gaps = 1/193 (0%)
Frame = +2
Query: 200 MILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRL 379
++++ S D T VW++ G + L GH+ + +VL + G+ A +GS D T+R
Sbjct: 37 LLVTGSTDGTAKVWQVAS-----GCCHQTLRGHTGAVLCLVLDTPGHTAFTGSTDATIRA 91
Query: 380 WDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLW-NTLAECKYTIQDDGHS 556
WD+ +G+ R F +H V + + NR + SGS D+T+K W EC T H
Sbjct: 92 WDILSGEQLRVFREHRGSV--ICLELVNRLVYSGSADRTVKCWLADTGECVRTF--TAHR 147
Query: 557 DWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCA 736
VS +++ HA + G D + + + +L+ GH+ +N + V G +
Sbjct: 148 RNVSALKY---HAGTLFTGSG-DACARAFDAQSGELRRVFRGHTFIINCIQV--HGQVLY 201
Query: 737 SGGKDMXAMLWDL 775
+ D LWD+
Sbjct: 202 TASHDGALRLWDV 214
Score = 50.8 bits (116), Expect = 6e-06
Identities = 30/103 (29%), Positives = 48/103 (46%)
Frame = +2
Query: 335 GNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNT 514
G ++GS D T ++W +A+G + HT VL + +GS D TI+ W+
Sbjct: 35 GGLLVTGSTDGTAKVWQVASGCCHQTLRGHTGAVLCLVLDTPGHTAFTGSTDATIRAWDI 94
Query: 515 LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVW 643
L+ + + + H V C+ N ++ S DRTVK W
Sbjct: 95 LSGEQLRVFRE-HRGSVICLEL----VNRLVYSGSADRTVKCW 132
Score = 33.9 bits (74), Expect = 0.68
Identities = 17/67 (25%), Positives = 29/67 (43%)
Frame = +2
Query: 593 ANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
A ++V+ D T KVW + + GH+G + + + G +G D WD
Sbjct: 34 AGGLLVTGSTDGTAKVWQVASGCCHQTLRGHTGAVLCLVLDTPGHTAFTGSTDATIRAWD 93
Query: 773 LNDGKHL 793
+ G+ L
Sbjct: 94 ILSGEQL 100
>BC068003-1|AAH68003.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2 protein.
Length = 340
Score = 77.8 bits (183), Expect = 4e-14
Identities = 59/213 (27%), Positives = 95/213 (44%), Gaps = 3/213 (1%)
Frame = +2
Query: 155 NGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSD 334
+ WV A P + + D ++ L E N + + L GH+ ++S D
Sbjct: 97 SSWVMTCAYAPS-GNFVACGGLDNICSIYSLKTREGNVRV-SRELPGHTGYLSCCRFLDD 154
Query: 335 GNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNT 514
N ++ S D T LWD+ G+ T F H+ DV+S++ + D R VSG+ D +IKLW+
Sbjct: 155 -NQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDV 213
Query: 515 L-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK--LKINHLGH 685
+ C+ T GH ++ V F PN + D T +++ L + L +H
Sbjct: 214 RDSMCRQTF--IGHESDINAVAFFPN--GYAFTTGSDDATCRLFDLRADQELLMYSHDNI 269
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDG 784
+ +V S G L +G D +WD G
Sbjct: 270 ICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKG 302
Score = 75.4 bits (177), Expect = 2e-13
Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 4/227 (1%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSH 304
++ R TLRGH + + +++S+S+D LI+W + IP + S
Sbjct: 45 MRTRRTLRGHLAKIYAMHWGTD-SRLLVSASQDGKLIIWDSYTTNKVHAIPLR-----SS 98
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAG----KTTRRFEDHTKDVLSVAFSVDNRQI 472
++ + GN+ G D ++ L + +R HT LS +D+ QI
Sbjct: 99 WVMTCAYAPSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHT-GYLSCCRFLDDNQI 157
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
++ S D T LW+ + + T+ GHS V + +P+ + +C D ++K+W +
Sbjct: 158 ITSSGDTTCALWD-IETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGAC--DASIKLWDVR 214
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ + +GH +N V P+G +G D L+DL + L
Sbjct: 215 DSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQEL 261
Score = 68.1 bits (159), Expect = 3e-11
Identities = 50/211 (23%), Positives = 94/211 (44%), Gaps = 1/211 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH G+++ + I++SS D T +W + + G GHS + +
Sbjct: 139 LPGHTGYLS--CCRFLDDNQIITSSGDTTCALWDIETGQQTVGFA-----GHSGDVMSLS 191
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
L+ DG +SG+ D +++LWD+ + F H D+ +VAF + +GS D T +
Sbjct: 192 LAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCR 251
Query: 503 LWNTLAECKYTIQD-DGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
L++ A+ + + D ++ V FS + ++++ D +W
Sbjct: 252 LFDLRADQELLMYSHDNIICGITSVAFS--RSGRLLLAGYDDFNCNIWDAMKGDRAGVLA 309
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
GH ++ + V+ DG A+G D +W+
Sbjct: 310 GHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>BC047921-1|AAH47921.1| 563|Homo sapiens WDR86 protein protein.
Length = 563
Score = 77.8 bits (183), Expect = 4e-14
Identities = 54/193 (27%), Positives = 92/193 (47%), Gaps = 1/193 (0%)
Frame = +2
Query: 200 MILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRL 379
++++ S D T VW++ G + L GH+ + +VL + G+ A +GS D T+R
Sbjct: 352 LLVTGSTDGTAKVWQVAS-----GCCHQTLRGHTGAVLCLVLDTPGHTAFTGSTDATIRA 406
Query: 380 WDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLW-NTLAECKYTIQDDGHS 556
WD+ +G+ R F +H V + + NR + SGS D+T+K W EC T H
Sbjct: 407 WDILSGEQLRVFREHRGSV--ICLELVNRLVYSGSADRTVKCWLADTGECVRTF--TAHR 462
Query: 557 DWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCA 736
VS +++ HA + G D + + + +L+ GH+ +N + V G +
Sbjct: 463 RNVSALKY---HAGTLFTGSG-DACARAFDAQSGELRRVFRGHTFIINCIQV--HGQVLY 516
Query: 737 SGGKDMXAMLWDL 775
+ D LWD+
Sbjct: 517 TASHDGALRLWDV 529
Score = 59.3 bits (137), Expect = 2e-08
Identities = 45/182 (24%), Positives = 82/182 (45%), Gaps = 12/182 (6%)
Frame = +2
Query: 284 RLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDN 463
RL GH +++ L + + S D T+R WD+ G+ + + HT V + V N
Sbjct: 239 RLGGHESYVTFCQLEDEAAFTCSA--DCTIRRWDVLTGQCLQVYRGHTSIVNRIL--VAN 294
Query: 464 RQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFS-----PNH-------ANPII 607
Q+ S S D+T ++W+ + + + + + GH + V + +S P+ A ++
Sbjct: 295 NQLFSSSYDRTARVWS-VDKGQMSREFRGHRNCVLTLAYSAPWDLPSTPCAEEAAAGGLL 353
Query: 608 VSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGK 787
V+ D T KVW + + GH+G + + + G +G D WD+ G+
Sbjct: 354 VTGSTDGTAKVWQVASGCCHQTLRGHTGAVLCLVLDTPGHTAFTGSTDATIRAWDILSGE 413
Query: 788 HL 793
L
Sbjct: 414 QL 415
Score = 52.8 bits (121), Expect = 1e-06
Identities = 46/180 (25%), Positives = 75/180 (41%), Gaps = 14/180 (7%)
Frame = +2
Query: 146 RGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVL 325
RGH V +I + + SSS D+T VW + + G + GH + + +
Sbjct: 281 RGHTSIVNRILVAN---NQLFSSSYDRTARVWSVDK-----GQMSREFRGHRNCVLTLAY 332
Query: 326 SSD--------------GNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDN 463
S+ G ++GS D T ++W +A+G + HT VL +
Sbjct: 333 SAPWDLPSTPCAEEAAAGGLLVTGSTDGTAKVWQVASGCCHQTLRGHTGAVLCLVLDTPG 392
Query: 464 RQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVW 643
+GS D TI+ W+ L+ + + + H V C+ N ++ S DRTVK W
Sbjct: 393 HTAFTGSTDATIRAWDILSGEQLRVFRE-HRGSVICLEL----VNRLVYSGSADRTVKCW 447
Score = 35.1 bits (77), Expect = 0.29
Identities = 14/35 (40%), Positives = 21/35 (60%)
Frame = +2
Query: 683 HSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGK 787
H G +N +++SPDG +G +D A LW DG+
Sbjct: 86 HRGGINWLSLSPDGQRLLTGSEDGTARLWSTADGQ 120
Score = 31.5 bits (68), Expect = 3.6
Identities = 13/40 (32%), Positives = 23/40 (57%)
Frame = +2
Query: 395 GKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNT 514
G R DH + ++ S D +++++GS D T +LW+T
Sbjct: 77 GSALRVCADHRGGINWLSLSPDGQRLLTGSEDGTARLWST 116
Score = 31.5 bits (68), Expect = 3.6
Identities = 19/57 (33%), Positives = 26/57 (45%)
Frame = +2
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNR 466
H I+ + LS DG L+GS D T RLW A G+ + L F+ +R
Sbjct: 86 HRGGINWLSLSPDGQRLLTGSEDGTARLWSTADGQCCALLQGRPSHSLPDLFAAAHR 142
>BC032551-1|AAH32551.1| 795|Homo sapiens phospholipase
A2-activating protein protein.
Length = 795
Score = 77.8 bits (183), Expect = 4e-14
Identities = 61/236 (25%), Positives = 107/236 (45%), Gaps = 4/236 (1%)
Frame = +2
Query: 74 RFRESSLFKPFSKMSETLKLRGTLRGHNGWVTQIATNPK---YPD-MILSSSRDKTLIVW 241
R R + L+ P S ++ + GH+ +V+ + P YP +I + D + ++
Sbjct: 39 RDRTTRLWAPDSPNRSFTEMH-CMSGHSNFVSCVCIIPSSDIYPHGLIATGGNDHNICIF 97
Query: 242 KLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFED 421
L +P L GH + + + G LSGSWD T ++W K +
Sbjct: 98 SLDSP-----MPLYILKGHKNTVCSLSSGKFGTL-LSGSWDTTAKVW--LNDKCMMTLQG 149
Query: 422 HTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANP 601
HT V +V + +++GS DKT+KLW C+ T GH D CVR +
Sbjct: 150 HTAAVWAVKILPEQGLMLTGSADKTVKLWKA-GRCERTF--SGHED---CVRGLAILSET 203
Query: 602 IIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
+SC D +++ W +T L++ + GH+ Y+ +++V P+ + +D +W
Sbjct: 204 EFLSCANDASIRRWQITGECLEV-YYGHTNYIYSISVFPNCRDFVTTAEDRSLRIW 258
Score = 55.2 bits (127), Expect = 3e-07
Identities = 54/185 (29%), Positives = 87/185 (47%), Gaps = 7/185 (3%)
Frame = +2
Query: 128 KLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKR-LYGHSH 304
+L +LRGH V + P +S SRD+T +W D N + + GHS+
Sbjct: 9 RLSCSLRGHELDVRGLVCCAYPPGAFVSVSRDRTTRLW--APDSPNRSFTEMHCMSGHSN 66
Query: 305 FISDVVL--SSD----GNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNR 466
F+S V + SSD G A G+ D + ++ L + + H V S++ S
Sbjct: 67 FVSCVCIIPSSDIYPHGLIATGGN-DHNICIFSLDSPMPLYILKGHKNTVCSLS-SGKFG 124
Query: 467 QIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWH 646
++SGS D T K+W +C T+Q GH+ V V+ P ++++ D+TVK+W
Sbjct: 125 TLLSGSWDTTAKVWLN-DKCMMTLQ--GHTAAVWAVKILPEQG--LMLTGSADKTVKLWK 179
Query: 647 LTNCK 661
C+
Sbjct: 180 AGRCE 184
>BC012348-1|AAH12348.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2 protein.
Length = 340
Score = 77.8 bits (183), Expect = 4e-14
Identities = 59/213 (27%), Positives = 95/213 (44%), Gaps = 3/213 (1%)
Frame = +2
Query: 155 NGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSD 334
+ WV A P + + D ++ L E N + + L GH+ ++S D
Sbjct: 97 SSWVMTCAYAPS-GNFVACGGLDNICSIYSLKTREGNVRV-SRELPGHTGYLSCCRFLDD 154
Query: 335 GNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNT 514
N ++ S D T LWD+ G+ T F H+ DV+S++ + D R VSG+ D +IKLW+
Sbjct: 155 -NQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDV 213
Query: 515 L-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK--LKINHLGH 685
+ C+ T GH ++ V F PN + D T +++ L + L +H
Sbjct: 214 RDSMCRQTF--IGHESDINAVAFFPN--GYAFTTGSDDATCRLFDLRADQELLMYSHDNI 269
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDG 784
+ +V S G L +G D +WD G
Sbjct: 270 ICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKG 302
Score = 75.4 bits (177), Expect = 2e-13
Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 4/227 (1%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSH 304
++ R TLRGH + + +++S+S+D LI+W + IP + S
Sbjct: 45 MRTRRTLRGHLAKIYAMHWGTD-SRLLVSASQDGKLIIWDSYTTNKVHAIPLR-----SS 98
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAG----KTTRRFEDHTKDVLSVAFSVDNRQI 472
++ + GN+ G D ++ L + +R HT LS +D+ QI
Sbjct: 99 WVMTCAYAPSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHT-GYLSCCRFLDDNQI 157
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
++ S D T LW+ + + T+ GHS V + +P+ + +C D ++K+W +
Sbjct: 158 ITSSGDTTCALWD-IETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGAC--DASIKLWDVR 214
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ + +GH +N V P+G +G D L+DL + L
Sbjct: 215 DSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQEL 261
Score = 68.1 bits (159), Expect = 3e-11
Identities = 50/211 (23%), Positives = 94/211 (44%), Gaps = 1/211 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH G+++ + I++SS D T +W + + G GHS + +
Sbjct: 139 LPGHTGYLS--CCRFLDDNQIITSSGDTTCALWDIETGQQTVGFA-----GHSGDVMSLS 191
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
L+ DG +SG+ D +++LWD+ + F H D+ +VAF + +GS D T +
Sbjct: 192 LAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCR 251
Query: 503 LWNTLAECKYTIQD-DGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
L++ A+ + + D ++ V FS + ++++ D +W
Sbjct: 252 LFDLRADQELLMYSHDNIICGITSVAFS--RSGRLLLAGYDDFNCNIWDAMKGDRAGVLA 309
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
GH ++ + V+ DG A+G D +W+
Sbjct: 310 GHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>BC010073-1|AAH10073.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2 protein.
Length = 340
Score = 77.8 bits (183), Expect = 4e-14
Identities = 59/213 (27%), Positives = 95/213 (44%), Gaps = 3/213 (1%)
Frame = +2
Query: 155 NGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSD 334
+ WV A P + + D ++ L E N + + L GH+ ++S D
Sbjct: 97 SSWVMTCAYAPS-GNFVACGGLDNICSIYSLKTREGNVRV-SRELPGHTGYLSCCRFLDD 154
Query: 335 GNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNT 514
N ++ S D T LWD+ G+ T F H+ DV+S++ + D R VSG+ D +IKLW+
Sbjct: 155 -NQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDV 213
Query: 515 L-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK--LKINHLGH 685
+ C+ T GH ++ V F PN + D T +++ L + L +H
Sbjct: 214 RDSMCRQTF--IGHESDINAVAFFPN--GYAFTTGSDDATCRLFDLRADQELLMYSHDNI 269
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDG 784
+ +V S G L +G D +WD G
Sbjct: 270 ICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKG 302
Score = 75.4 bits (177), Expect = 2e-13
Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 4/227 (1%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSH 304
++ R TLRGH + + +++S+S+D LI+W + IP + S
Sbjct: 45 MRTRRTLRGHLAKIYAMHWGTD-SRLLVSASQDGKLIIWDSYTTNKVHAIPLR-----SS 98
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAG----KTTRRFEDHTKDVLSVAFSVDNRQI 472
++ + GN+ G D ++ L + +R HT LS +D+ QI
Sbjct: 99 WVMTCAYAPSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHT-GYLSCCRFLDDNQI 157
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
++ S D T LW+ + + T+ GHS V + +P+ + +C D ++K+W +
Sbjct: 158 ITSSGDTTCALWD-IETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGAC--DASIKLWDVR 214
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ + +GH +N V P+G +G D L+DL + L
Sbjct: 215 DSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQEL 261
Score = 68.1 bits (159), Expect = 3e-11
Identities = 50/211 (23%), Positives = 94/211 (44%), Gaps = 1/211 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH G+++ + I++SS D T +W + + G GHS + +
Sbjct: 139 LPGHTGYLS--CCRFLDDNQIITSSGDTTCALWDIETGQQTVGFA-----GHSGDVMSLS 191
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
L+ DG +SG+ D +++LWD+ + F H D+ +VAF + +GS D T +
Sbjct: 192 LAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCR 251
Query: 503 LWNTLAECKYTIQD-DGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
L++ A+ + + D ++ V FS + ++++ D +W
Sbjct: 252 LFDLRADQELLMYSHDNIICGITSVAFS--RSGRLLLAGYDDFNCNIWDAMKGDRAGVLA 309
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
GH ++ + V+ DG A+G D +W+
Sbjct: 310 GHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>BC000873-1|AAH00873.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 4 protein.
Length = 340
Score = 77.8 bits (183), Expect = 4e-14
Identities = 62/228 (27%), Positives = 102/228 (44%), Gaps = 5/228 (2%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYPDMIL-SSSRDKTLIVWKLTRDENNYGIPQKRLYGHS 301
++ R TLRGH + A + Y +L S+S+D LI+W + IP + S
Sbjct: 45 MRTRRTLRGHLAKI--YAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLR-----S 97
Query: 302 HFISDVVLSSDGNYALSGSWDKTLRLWDLAAG----KTTRRFEDHTKDVLSVAFSVDNRQ 469
++ + GNY G D +++L + +R HT LS +D+ Q
Sbjct: 98 SWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELPGHT-GYLSCCRFLDDSQ 156
Query: 470 IVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 649
IV+ S D T LW+ + + T GHS V + SP+ + +C D + K+W +
Sbjct: 157 IVTSSGDTTCALWD-IETAQQTTTFTGHSGDVMSLSLSPDMRTFVSGAC--DASSKLWDI 213
Query: 650 TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ + + GH +N V+ P+G A+G D L+DL + L
Sbjct: 214 RDGMCRQSFTGHVSDINAVSFFPNGYAFATGSDDATCRLFDLRADQEL 261
Score = 68.9 bits (161), Expect = 2e-11
Identities = 57/213 (26%), Positives = 90/213 (42%), Gaps = 3/213 (1%)
Frame = +2
Query: 155 NGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSD 334
+ WV A P + + D ++ L E N + + L GH+ ++S D
Sbjct: 97 SSWVMTCAYAPS-GNYVACGGLDNICSIYNLKTREGNVRV-SRELPGHTGYLSCCRFLDD 154
Query: 335 GNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNT 514
S S D T LWD+ + T F H+ DV+S++ S D R VSG+ D + KLW+
Sbjct: 155 SQIVTS-SGDTTCALWDIETAQQTTTFTGHSGDVMSLSLSPDMRTFVSGACDASSKLWDI 213
Query: 515 L-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK--LKINHLGH 685
C+ + GH ++ V F PN + D T +++ L + L +H
Sbjct: 214 RDGMCRQSF--TGHVSDINAVSFFPN--GYAFATGSDDATCRLFDLRADQELLLYSHDNI 269
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDG 784
+ +V S G L +G D +WD G
Sbjct: 270 ICGITSVAFSKSGRLLLAGYDDFNCNVWDTLKG 302
Score = 62.9 bits (146), Expect = 1e-09
Identities = 51/212 (24%), Positives = 91/212 (42%), Gaps = 2/212 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH G+++ I++SS D T +W + + GHS + +
Sbjct: 139 LPGHTGYLS--CCRFLDDSQIVTSSGDTTCALWDIETAQQT-----TTFTGHSGDVMSLS 191
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
LS D +SG+ D + +LWD+ G + F H D+ +V+F + +GS D T +
Sbjct: 192 LSPDMRTFVSGACDASSKLWDIRDGMCRQSFTGHVSDINAVSFFPNGYAFATGSDDATCR 251
Query: 503 LWNTLAECKYTIQD-DGHSDWVSCVRFSPNHANPIIVSCGWDR-TVKVWHLTNCKLKINH 676
L++ A+ + + D ++ V FS + ++ G+D VW
Sbjct: 252 LFDLRADQELLLYSHDNIICGITSVAFSKSGR---LLLAGYDDFNCNVWDTLKGDRAGVL 308
Query: 677 LGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
GH ++ + V+ DG A+G D +W+
Sbjct: 309 AGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN 340
>AK002143-1|BAA92105.1| 544|Homo sapiens protein ( Homo sapiens
cDNA FLJ11281 fis, clone PLACE1009468, highly similar to
PHOSPHOLIPASE A-2-ACTIVATING PROTEIN. ).
Length = 544
Score = 77.8 bits (183), Expect = 4e-14
Identities = 61/236 (25%), Positives = 107/236 (45%), Gaps = 4/236 (1%)
Frame = +2
Query: 74 RFRESSLFKPFSKMSETLKLRGTLRGHNGWVTQIATNPK---YPD-MILSSSRDKTLIVW 241
R R + L+ P S ++ + GH+ +V+ + P YP +I + D + ++
Sbjct: 39 RDRTTRLWAPDSPNRSFTEMH-CMSGHSNFVSCVCIIPSSDIYPHGLIATGGNDHNICIF 97
Query: 242 KLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFED 421
L +P L GH + + + G LSGSWD T ++W K +
Sbjct: 98 SLDSP-----MPLYILKGHKNTVCSLSSGKFGTL-LSGSWDTTAKVW--LNDKCMMTLQG 149
Query: 422 HTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANP 601
HT V +V + +++GS DKT+KLW C+ T GH D CVR +
Sbjct: 150 HTAAVWAVKILPEQGLMLTGSADKTVKLWKA-GRCERTF--SGHED---CVRGLAILSET 203
Query: 602 IIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
+SC D +++ W +T L++ + GH+ Y+ +++V P+ + +D +W
Sbjct: 204 EFLSCANDASIRRWQITGECLEV-YYGHTNYIYSISVFPNCRDFVTTAEDRSLRIW 258
Score = 55.2 bits (127), Expect = 3e-07
Identities = 54/185 (29%), Positives = 87/185 (47%), Gaps = 7/185 (3%)
Frame = +2
Query: 128 KLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKR-LYGHSH 304
+L +LRGH V + P +S SRD+T +W D N + + GHS+
Sbjct: 9 RLSCSLRGHELDVRGLVCCAYPPGAFVSVSRDRTTRLW--APDSPNRSFTEMHCMSGHSN 66
Query: 305 FISDVVL--SSD----GNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNR 466
F+S V + SSD G A G+ D + ++ L + + H V S++ S
Sbjct: 67 FVSCVCIIPSSDIYPHGLIATGGN-DHNICIFSLDSPMPLYILKGHKNTVCSLS-SGKFG 124
Query: 467 QIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWH 646
++SGS D T K+W +C T+Q GH+ V V+ P ++++ D+TVK+W
Sbjct: 125 TLLSGSWDTTAKVWLN-DKCMMTLQ--GHTAAVWAVKILPEQG--LMLTGSADKTVKLWK 179
Query: 647 LTNCK 661
C+
Sbjct: 180 AGRCE 184
>AF501883-1|AAM15919.1| 340|Homo sapiens guanine nucleotide binding
protein beta 2 protein.
Length = 340
Score = 77.8 bits (183), Expect = 4e-14
Identities = 59/213 (27%), Positives = 95/213 (44%), Gaps = 3/213 (1%)
Frame = +2
Query: 155 NGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSD 334
+ WV A P + + D ++ L E N + + L GH+ ++S D
Sbjct: 97 SSWVMTCAYAPS-GNFVACGGLDNICSIYSLKTREGNVRV-SRELPGHTGYLSCCRFLDD 154
Query: 335 GNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNT 514
N ++ S D T LWD+ G+ T F H+ DV+S++ + D R VSG+ D +IKLW+
Sbjct: 155 -NQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDV 213
Query: 515 L-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK--LKINHLGH 685
+ C+ T GH ++ V F PN + D T +++ L + L +H
Sbjct: 214 RDSMCRQTF--IGHESDINAVAFFPN--GYAFTTGSDDATCRLFDLRADQELLMYSHDNI 269
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDG 784
+ +V S G L +G D +WD G
Sbjct: 270 ICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKG 302
Score = 75.4 bits (177), Expect = 2e-13
Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 4/227 (1%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSH 304
++ R TLRGH + + +++S+S+D LI+W + IP + S
Sbjct: 45 MRTRRTLRGHLAKIYAMHWGTD-SRLLVSASQDGKLIIWDSYTTNKVHAIPLR-----SS 98
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAG----KTTRRFEDHTKDVLSVAFSVDNRQI 472
++ + GN+ G D ++ L + +R HT LS +D+ QI
Sbjct: 99 WVMTCAYAPSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHT-GYLSCCRFLDDNQI 157
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
++ S D T LW+ + + T+ GHS V + +P+ + +C D ++K+W +
Sbjct: 158 ITSSGDTTCALWD-IETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGAC--DASIKLWDVR 214
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ + +GH +N V P+G +G D L+DL + L
Sbjct: 215 DSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQEL 261
Score = 68.1 bits (159), Expect = 3e-11
Identities = 50/211 (23%), Positives = 94/211 (44%), Gaps = 1/211 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH G+++ + I++SS D T +W + + G GHS + +
Sbjct: 139 LPGHTGYLS--CCRFLDDNQIITSSGDTTCALWDIETGQQTVGFA-----GHSGDVMSLS 191
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
L+ DG +SG+ D +++LWD+ + F H D+ +VAF + +GS D T +
Sbjct: 192 LAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCR 251
Query: 503 LWNTLAECKYTIQD-DGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
L++ A+ + + D ++ V FS + ++++ D +W
Sbjct: 252 LFDLRADQELLMYSHDNIICGITSVAFS--RSGRLLLAGYDDFNCNIWDAMKGDRAGVLA 309
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
GH ++ + V+ DG A+G D +W+
Sbjct: 310 GHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>AF300648-1|AAG18442.1| 340|Homo sapiens guanine nucleotide binding
protein beta subunit 4 protein.
Length = 340
Score = 77.8 bits (183), Expect = 4e-14
Identities = 62/228 (27%), Positives = 102/228 (44%), Gaps = 5/228 (2%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYPDMIL-SSSRDKTLIVWKLTRDENNYGIPQKRLYGHS 301
++ R TLRGH + A + Y +L S+S+D LI+W + IP + S
Sbjct: 45 MRTRRTLRGHLAKI--YAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLR-----S 97
Query: 302 HFISDVVLSSDGNYALSGSWDKTLRLWDLAAG----KTTRRFEDHTKDVLSVAFSVDNRQ 469
++ + GNY G D +++L + +R HT LS +D+ Q
Sbjct: 98 SWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELPGHT-GYLSCCRFLDDSQ 156
Query: 470 IVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 649
IV+ S D T LW+ + + T GHS V + SP+ + +C D + K+W +
Sbjct: 157 IVTSSGDTTCALWD-IETAQQTTTFTGHSGDVMSLSLSPDMRTFVSGAC--DASSKLWDI 213
Query: 650 TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ + + GH +N V+ P+G A+G D L+DL + L
Sbjct: 214 RDGMCRQSFTGHVSDINAVSFFPNGYAFATGSDDATCRLFDLRADQEL 261
Score = 68.9 bits (161), Expect = 2e-11
Identities = 57/213 (26%), Positives = 90/213 (42%), Gaps = 3/213 (1%)
Frame = +2
Query: 155 NGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSD 334
+ WV A P + + D ++ L E N + + L GH+ ++S D
Sbjct: 97 SSWVMTCAYAPS-GNYVACGGLDNICSIYNLKTREGNVRV-SRELPGHTGYLSCCRFLDD 154
Query: 335 GNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNT 514
S S D T LWD+ + T F H+ DV+S++ S D R VSG+ D + KLW+
Sbjct: 155 SQIVTS-SGDTTCALWDIETAQQTTTFTGHSGDVMSLSLSPDMRTFVSGACDASSKLWDI 213
Query: 515 L-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK--LKINHLGH 685
C+ + GH ++ V F PN + D T +++ L + L +H
Sbjct: 214 RDGMCRQSF--TGHVSDINAVSFFPN--GYAFATGSDDATCRLFDLRADQELLLYSHDNI 269
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDG 784
+ +V S G L +G D +WD G
Sbjct: 270 ICGITSVAFSKSGRLLLAGYDDFNCNVWDTLKG 302
Score = 62.9 bits (146), Expect = 1e-09
Identities = 51/212 (24%), Positives = 91/212 (42%), Gaps = 2/212 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH G+++ I++SS D T +W + + GHS + +
Sbjct: 139 LPGHTGYLS--CCRFLDDSQIVTSSGDTTCALWDIETAQQT-----TTFTGHSGDVMSLS 191
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
LS D +SG+ D + +LWD+ G + F H D+ +V+F + +GS D T +
Sbjct: 192 LSPDMRTFVSGACDASSKLWDIRDGMCRQSFTGHVSDINAVSFFPNGYAFATGSDDATCR 251
Query: 503 LWNTLAECKYTIQD-DGHSDWVSCVRFSPNHANPIIVSCGWDR-TVKVWHLTNCKLKINH 676
L++ A+ + + D ++ V FS + ++ G+D VW
Sbjct: 252 LFDLRADQELLLYSHDNIICGITSVAFSKSGR---LLLAGYDDFNCNVWDTLKGDRAGVL 308
Query: 677 LGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
GH ++ + V+ DG A+G D +W+
Sbjct: 309 AGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN 340
>AF053356-4|AAC78794.1| 340|Homo sapiens GNB2 protein.
Length = 340
Score = 77.8 bits (183), Expect = 4e-14
Identities = 59/213 (27%), Positives = 95/213 (44%), Gaps = 3/213 (1%)
Frame = +2
Query: 155 NGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSD 334
+ WV A P + + D ++ L E N + + L GH+ ++S D
Sbjct: 97 SSWVMTCAYAPS-GNFVACGGLDNICSIYSLKTREGNVRV-SRELPGHTGYLSCCRFLDD 154
Query: 335 GNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNT 514
N ++ S D T LWD+ G+ T F H+ DV+S++ + D R VSG+ D +IKLW+
Sbjct: 155 -NQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDV 213
Query: 515 L-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK--LKINHLGH 685
+ C+ T GH ++ V F PN + D T +++ L + L +H
Sbjct: 214 RDSMCRQTF--IGHESDINAVAFFPN--GYAFTTGSDDATCRLFDLRADQELLMYSHDNI 269
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDG 784
+ +V S G L +G D +WD G
Sbjct: 270 ICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKG 302
Score = 75.4 bits (177), Expect = 2e-13
Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 4/227 (1%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSH 304
++ R TLRGH + + +++S+S+D LI+W + IP + S
Sbjct: 45 MRTRRTLRGHLAKIYAMHWGTD-SRLLVSASQDGKLIIWDSYTTNKVHAIPLR-----SS 98
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAG----KTTRRFEDHTKDVLSVAFSVDNRQI 472
++ + GN+ G D ++ L + +R HT LS +D+ QI
Sbjct: 99 WVMTCAYAPSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHT-GYLSCCRFLDDNQI 157
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
++ S D T LW+ + + T+ GHS V + +P+ + +C D ++K+W +
Sbjct: 158 ITSSGDTTCALWD-IETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGAC--DASIKLWDVR 214
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ + +GH +N V P+G +G D L+DL + L
Sbjct: 215 DSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQEL 261
Score = 68.1 bits (159), Expect = 3e-11
Identities = 50/211 (23%), Positives = 94/211 (44%), Gaps = 1/211 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH G+++ + I++SS D T +W + + G GHS + +
Sbjct: 139 LPGHTGYLS--CCRFLDDNQIITSSGDTTCALWDIETGQQTVGFA-----GHSGDVMSLS 191
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
L+ DG +SG+ D +++LWD+ + F H D+ +VAF + +GS D T +
Sbjct: 192 LAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCR 251
Query: 503 LWNTLAECKYTIQD-DGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
L++ A+ + + D ++ V FS + ++++ D +W
Sbjct: 252 LFDLRADQELLMYSHDNIICGITSVAFS--RSGRLLLAGYDDFNCNIWDAMKGDRAGVLA 309
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
GH ++ + V+ DG A+G D +W+
Sbjct: 310 GHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>EF011613-1|ABK41103.1| 513|Homo sapiens CDW3/SMU1 protein.
Length = 513
Score = 77.4 bits (182), Expect = 6e-14
Identities = 44/170 (25%), Positives = 79/170 (46%), Gaps = 8/170 (4%)
Frame = +2
Query: 290 YGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKD--------VLSV 445
+G + S DG Y ++GS D + +W+ GK + + +D VL +
Sbjct: 211 FGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCM 270
Query: 446 AFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWD 625
FS D + +G++D IK+W + + HS V+C+ FS + + I+S +D
Sbjct: 271 CFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQ--ILSASFD 328
Query: 626 RTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
+T+++ L + K GHS ++N T + DG S D +W++
Sbjct: 329 QTIRIHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNM 378
Score = 68.1 bits (159), Expect = 3e-11
Identities = 52/204 (25%), Positives = 90/204 (44%), Gaps = 7/204 (3%)
Frame = +2
Query: 197 DMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLR 376
+M+ + ++D + VWK+ + ++ HS ++ + S D + LS S+D+T+R
Sbjct: 277 EMLATGAQDGKIKVWKIQSGQ----CLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIR 332
Query: 377 LWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN-TLAECKYTIQDDGH 553
+ L +GKT + F H+ V F+ D I+S S D T+K+WN EC T + G
Sbjct: 333 IHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFKSLGS 392
Query: 554 SD----WVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLG--HSGYLNTVTVS 715
+ V+ V P + +V C TV + ++ ++ G G +S
Sbjct: 393 TAGTDITVNSVILLPKNPEHFVV-CNRSNTVVIMNMQGQIVRSFSSGKREGGDFVCCALS 451
Query: 716 PDGSLCASGGKDMXAMLWDLNDGK 787
P G G+D + GK
Sbjct: 452 PRGEWIYCVGEDFVLYCFSTVTGK 475
Score = 42.7 bits (96), Expect = 0.001
Identities = 34/134 (25%), Positives = 53/134 (39%)
Frame = +2
Query: 107 SKMSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKR 286
++ S T K G+ G + V + PK P+ + +R T+++ + KR
Sbjct: 381 TECSNTFKSLGSTAGTDITVNSVILLPKNPEHFVVCNRSNTVVIMNMQGQIVRSFSSGKR 440
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNR 466
G F+ LS G + D L + GK R H KDV+ +A
Sbjct: 441 EGGD--FVC-CALSPRGEWIYCVGEDFVLYCFSTVTGKLERTLTVHEKDVIGIAHHPHQN 497
Query: 467 QIVSGSRDKTIKLW 508
I + S D +KLW
Sbjct: 498 LIATYSEDGLLKLW 511
>BC110654-1|AAI10655.1| 513|Homo sapiens smu-1 suppressor of mec-8
and unc-52 homolog (C. elegans) protein.
Length = 513
Score = 77.4 bits (182), Expect = 6e-14
Identities = 44/170 (25%), Positives = 79/170 (46%), Gaps = 8/170 (4%)
Frame = +2
Query: 290 YGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKD--------VLSV 445
+G + S DG Y ++GS D + +W+ GK + + +D VL +
Sbjct: 211 FGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCM 270
Query: 446 AFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWD 625
FS D + +G++D IK+W + + HS V+C+ FS + + I+S +D
Sbjct: 271 CFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQ--ILSASFD 328
Query: 626 RTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
+T+++ L + K GHS ++N T + DG S D +W++
Sbjct: 329 QTIRIHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNM 378
Score = 68.1 bits (159), Expect = 3e-11
Identities = 52/204 (25%), Positives = 90/204 (44%), Gaps = 7/204 (3%)
Frame = +2
Query: 197 DMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLR 376
+M+ + ++D + VWK+ + ++ HS ++ + S D + LS S+D+T+R
Sbjct: 277 EMLATGAQDGKIKVWKIQSGQ----CLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIR 332
Query: 377 LWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN-TLAECKYTIQDDGH 553
+ L +GKT + F H+ V F+ D I+S S D T+K+WN EC T + G
Sbjct: 333 IHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFKSLGS 392
Query: 554 SD----WVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLG--HSGYLNTVTVS 715
+ V+ V P + +V C TV + ++ ++ G G +S
Sbjct: 393 TAGTDITVNSVILLPKNPEHFVV-CNRSNTVVIMNMQGQIVRSFSSGKREGGDFVCCALS 451
Query: 716 PDGSLCASGGKDMXAMLWDLNDGK 787
P G G+D + GK
Sbjct: 452 PRGEWIYCVGEDFVLYCFSTVTGK 475
Score = 43.2 bits (97), Expect = 0.001
Identities = 34/134 (25%), Positives = 53/134 (39%)
Frame = +2
Query: 107 SKMSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKR 286
++ S T K G+ G + V + PK P+ + +R T+++ + KR
Sbjct: 381 TECSNTFKSLGSTAGTDITVNSVILLPKNPEHFVVCNRSNTVVIMNMQGQIVRSFSSGKR 440
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNR 466
G F+ LS G + D L + GK R H KDV+ +A
Sbjct: 441 EGGD--FVC-CALSPRGEWIYCVGEDFVLYCFSTVTGKLERTLTVHEKDVIGIAHHPHQN 497
Query: 467 QIVSGSRDKTIKLW 508
I + S D +KLW
Sbjct: 498 LIATYSEDALLKLW 511
>BC002876-1|AAH02876.1| 513|Homo sapiens smu-1 suppressor of mec-8
and unc-52 homolog (C. elegans) protein.
Length = 513
Score = 77.4 bits (182), Expect = 6e-14
Identities = 44/170 (25%), Positives = 79/170 (46%), Gaps = 8/170 (4%)
Frame = +2
Query: 290 YGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKD--------VLSV 445
+G + S DG Y ++GS D + +W+ GK + + +D VL +
Sbjct: 211 FGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCM 270
Query: 446 AFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWD 625
FS D + +G++D IK+W + + HS V+C+ FS + + I+S +D
Sbjct: 271 CFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQ--ILSASFD 328
Query: 626 RTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
+T+++ L + K GHS ++N T + DG S D +W++
Sbjct: 329 QTIRIHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNM 378
Score = 68.1 bits (159), Expect = 3e-11
Identities = 52/204 (25%), Positives = 90/204 (44%), Gaps = 7/204 (3%)
Frame = +2
Query: 197 DMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLR 376
+M+ + ++D + VWK+ + ++ HS ++ + S D + LS S+D+T+R
Sbjct: 277 EMLATGAQDGKIKVWKIQSGQ----CLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIR 332
Query: 377 LWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN-TLAECKYTIQDDGH 553
+ L +GKT + F H+ V F+ D I+S S D T+K+WN EC T + G
Sbjct: 333 IHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFKSLGS 392
Query: 554 SD----WVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLG--HSGYLNTVTVS 715
+ V+ V P + +V C TV + ++ ++ G G +S
Sbjct: 393 TAGTDITVNSVILLPKNPEHFVV-CNRSNTVVIMNMQGQIVRSFSSGKREGGDFVCCALS 451
Query: 716 PDGSLCASGGKDMXAMLWDLNDGK 787
P G G+D + GK
Sbjct: 452 PRGEWIYCVGEDFVLYCFSTVTGK 475
Score = 42.7 bits (96), Expect = 0.001
Identities = 34/134 (25%), Positives = 53/134 (39%)
Frame = +2
Query: 107 SKMSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKR 286
++ S T K G+ G + V + PK P+ + +R T+++ + KR
Sbjct: 381 TECSNTFKSLGSTAGTDITVNSVILLPKNPEHFVVCNRSNTVVIMNMQGQIVRSFSSGKR 440
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNR 466
G F+ LS G + D L + GK R H KDV+ +A
Sbjct: 441 EGGD--FVC-CALSPRGEWIYCVGEDFVLYCFSTVTGKLERTLTVHEKDVIGIAHHPHQN 497
Query: 467 QIVSGSRDKTIKLW 508
I + S D +KLW
Sbjct: 498 LIATYSEDGLLKLW 511
>AL162590-6|CAI15554.1| 513|Homo sapiens smu-1 suppressor of mec-8
and unc-52 homolog (C. elegans) protein.
Length = 513
Score = 77.4 bits (182), Expect = 6e-14
Identities = 44/170 (25%), Positives = 79/170 (46%), Gaps = 8/170 (4%)
Frame = +2
Query: 290 YGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKD--------VLSV 445
+G + S DG Y ++GS D + +W+ GK + + +D VL +
Sbjct: 211 FGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCM 270
Query: 446 AFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWD 625
FS D + +G++D IK+W + + HS V+C+ FS + + I+S +D
Sbjct: 271 CFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQ--ILSASFD 328
Query: 626 RTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
+T+++ L + K GHS ++N T + DG S D +W++
Sbjct: 329 QTIRIHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNM 378
Score = 68.1 bits (159), Expect = 3e-11
Identities = 52/204 (25%), Positives = 90/204 (44%), Gaps = 7/204 (3%)
Frame = +2
Query: 197 DMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLR 376
+M+ + ++D + VWK+ + ++ HS ++ + S D + LS S+D+T+R
Sbjct: 277 EMLATGAQDGKIKVWKIQSGQ----CLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIR 332
Query: 377 LWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN-TLAECKYTIQDDGH 553
+ L +GKT + F H+ V F+ D I+S S D T+K+WN EC T + G
Sbjct: 333 IHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFKSLGS 392
Query: 554 SD----WVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLG--HSGYLNTVTVS 715
+ V+ V P + +V C TV + ++ ++ G G +S
Sbjct: 393 TAGTDITVNSVILLPKNPEHFVV-CNRSNTVVIMNMQGQIVRSFSSGKREGGDFVCCALS 451
Query: 716 PDGSLCASGGKDMXAMLWDLNDGK 787
P G G+D + GK
Sbjct: 452 PRGEWIYCVGEDFVLYCFSTVTGK 475
Score = 42.7 bits (96), Expect = 0.001
Identities = 34/134 (25%), Positives = 53/134 (39%)
Frame = +2
Query: 107 SKMSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKR 286
++ S T K G+ G + V + PK P+ + +R T+++ + KR
Sbjct: 381 TECSNTFKSLGSTAGTDITVNSVILLPKNPEHFVVCNRSNTVVIMNMQGQIVRSFSSGKR 440
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNR 466
G F+ LS G + D L + GK R H KDV+ +A
Sbjct: 441 EGGD--FVC-CALSPRGEWIYCVGEDFVLYCFSTVTGKLERTLTVHEKDVIGIAHHPHQN 497
Query: 467 QIVSGSRDKTIKLW 508
I + S D +KLW
Sbjct: 498 LIATYSEDGLLKLW 511
>AK022782-1|BAB14243.1| 423|Homo sapiens protein ( Homo sapiens
cDNA FLJ12720 fis, clone NT2RP1001302, weakly similar to
MICROTUBULE-ASSOCIATED PROTEIN YTM1. ).
Length = 423
Score = 77.4 bits (182), Expect = 6e-14
Identities = 52/162 (32%), Positives = 80/162 (49%), Gaps = 3/162 (1%)
Frame = +2
Query: 275 PQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFS 454
P L GH +S V L SD S SWD T+R+WD+ +G + K +++S
Sbjct: 249 PIVTLSGHMEAVSSV-LWSDAEEICSASWDHTIRVWDVGSGSLKSTLTGN-KVFNCISYS 306
Query: 455 VDNRQIVSGSRDKTIKLWN--TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR 628
+++ SGS D+ I+LW+ T ++ H+ WV+ V++SP H +I S D
Sbjct: 307 PLCKRLASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLI-SGSLDN 365
Query: 629 TVKVWHLTNCKLKINHL-GHSGYLNTVTVSPDGSLCASGGKD 751
VK+W +CK + L H + +V + D L SGG D
Sbjct: 366 IVKLWDTRSCKAPLYDLAAHEDKVLSVDWT-DTGLLLSGGAD 406
Score = 67.3 bits (157), Expect = 6e-11
Identities = 64/232 (27%), Positives = 97/232 (41%), Gaps = 9/232 (3%)
Frame = +2
Query: 104 FSKMSETLKLRG----TLRGHNGWVTQIATNPK--YPDMILSSSRDKTLIVWKLTRDENN 265
+ K S L G T+ GH V +A K ++LS+S D+T+++W+ + N
Sbjct: 119 YDKTSRIWSLEGKSIMTIVGHTDVVKDVAWVKKDSLSCLLLSASMDQTILLWEWNVERNK 178
Query: 266 YGIPQKRLY---GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDV 436
K L+ GH+ + + + G SGSWDK L++W E+ T
Sbjct: 179 V----KALHCCRGHAGSVDSIAVDGSGTKFCSGSWDKMLKIWSTVPTDEEDEMEEST--- 231
Query: 437 LSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSC 616
NR + KT +L T + GH + VS V +S I S
Sbjct: 232 --------NR---PRKKQKTEQLGLTRTP---IVTLSGHMEAVSSVLWSDAEE---ICSA 274
Query: 617 GWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
WD T++VW + + LK G+ + N ++ SP ASG D LWD
Sbjct: 275 SWDHTIRVWDVGSGSLKSTLTGNKVF-NCISYSPLCKRLASGSTDRHIRLWD 325
Score = 48.0 bits (109), Expect = 4e-05
Identities = 30/105 (28%), Positives = 56/105 (53%), Gaps = 5/105 (4%)
Frame = +2
Query: 470 IVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRF-SPNHANPIIVSCGWDRTVKVW- 643
I++GS DKT ++W+ + TI GH+D V V + + + +++S D+T+ +W
Sbjct: 114 ILTGSYDKTSRIWSLEGKSIMTIV--GHTDVVKDVAWVKKDSLSCLLLSASMDQTILLWE 171
Query: 644 -HLTNCKLKINHL--GHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
++ K+K H GH+G ++++ V G+ SG D +W
Sbjct: 172 WNVERNKVKALHCCRGHAGSVDSIAVDGSGTKFCSGSWDKMLKIW 216
Score = 46.8 bits (106), Expect = 9e-05
Identities = 36/129 (27%), Positives = 57/129 (44%), Gaps = 7/129 (5%)
Frame = +2
Query: 152 HNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSS 331
H+ W++ I ++ IL+ S DKT +W L G + GH+ + DV
Sbjct: 100 HDDWISSIKGAEEW---ILTGSYDKTSRIWSLE------GKSIMTIVGHTDVVKDVAWVK 150
Query: 332 DGNYA---LSGSWDKTLRLWDLAAG----KTTRRFEDHTKDVLSVAFSVDNRQIVSGSRD 490
+ + LS S D+T+ LW+ K H V S+A + SGS D
Sbjct: 151 KDSLSCLLLSASMDQTILLWEWNVERNKVKALHCCRGHAGSVDSIAVDGSGTKFCSGSWD 210
Query: 491 KTIKLWNTL 517
K +K+W+T+
Sbjct: 211 KMLKIWSTV 219
Score = 35.9 bits (79), Expect = 0.17
Identities = 27/98 (27%), Positives = 41/98 (41%)
Frame = +2
Query: 80 RESSLFKPFSKMSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDE 259
R L+ P +K + L +L H GWVT + +P + ++S S D + +W D
Sbjct: 319 RHIRLWDPRTKDGSLVSL--SLTSHTGWVTSVKWSPTHEQQLISGSLDNIVKLW----DT 372
Query: 260 NNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTL 373
+ P L H + V + G LSG D L
Sbjct: 373 RSCKAPLYDLAAHEDKVLSVDWTDTG-LLLSGGADNKL 409
>AK022781-1|BAB14242.1| 423|Homo sapiens protein ( Homo sapiens
cDNA FLJ12719 fis, clone NT2RP1001294, weakly similar to
MICROTUBULE-ASSOCIATED PROTEIN YTM1. ).
Length = 423
Score = 77.4 bits (182), Expect = 6e-14
Identities = 52/162 (32%), Positives = 80/162 (49%), Gaps = 3/162 (1%)
Frame = +2
Query: 275 PQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFS 454
P L GH +S V L SD S SWD T+R+WD+ +G + K +++S
Sbjct: 249 PIVTLSGHMEAVSSV-LWSDAEEICSASWDHTIRVWDVGSGSLKSTLTGN-KVFNCISYS 306
Query: 455 VDNRQIVSGSRDKTIKLWN--TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR 628
+++ SGS D+ I+LW+ T ++ H+ WV+ V++SP H +I S D
Sbjct: 307 PLCKRLASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLI-SGSLDN 365
Query: 629 TVKVWHLTNCKLKINHL-GHSGYLNTVTVSPDGSLCASGGKD 751
VK+W +CK + L H + +V + D L SGG D
Sbjct: 366 IVKLWDTRSCKAPLYDLAAHEDKVLSVDWT-DTGLLLSGGAD 406
Score = 67.3 bits (157), Expect = 6e-11
Identities = 64/232 (27%), Positives = 97/232 (41%), Gaps = 9/232 (3%)
Frame = +2
Query: 104 FSKMSETLKLRG----TLRGHNGWVTQIATNPK--YPDMILSSSRDKTLIVWKLTRDENN 265
+ K S L G T+ GH V +A K ++LS+S D+T+++W+ + N
Sbjct: 119 YDKTSRIWSLEGKSIMTIVGHTDVVKDVAWVKKDSLSCLLLSASMDQTILLWEWNVERNK 178
Query: 266 YGIPQKRLY---GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDV 436
K L+ GH+ + + + G SGSWDK L++W E+ T
Sbjct: 179 V----KALHCCRGHAGSVDSIAVDGSGTKFCSGSWDKMLKIWSTVPTDEEDEMEEST--- 231
Query: 437 LSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSC 616
NR + KT +L T + GH + VS V +S I S
Sbjct: 232 --------NR---PRKKQKTEQLGLTRTP---IVTLSGHMEAVSSVLWSDAEE---ICSA 274
Query: 617 GWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
WD T++VW + + LK G+ + N ++ SP ASG D LWD
Sbjct: 275 SWDHTIRVWDVGSGSLKSTLTGNKVF-NCISYSPLCKRLASGSTDRHIRLWD 325
Score = 48.0 bits (109), Expect = 4e-05
Identities = 30/105 (28%), Positives = 56/105 (53%), Gaps = 5/105 (4%)
Frame = +2
Query: 470 IVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRF-SPNHANPIIVSCGWDRTVKVW- 643
I++GS DKT ++W+ + TI GH+D V V + + + +++S D+T+ +W
Sbjct: 114 ILTGSYDKTSRIWSLEGKSIMTIV--GHTDVVKDVAWVKKDSLSCLLLSASMDQTILLWE 171
Query: 644 -HLTNCKLKINHL--GHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
++ K+K H GH+G ++++ V G+ SG D +W
Sbjct: 172 WNVERNKVKALHCCRGHAGSVDSIAVDGSGTKFCSGSWDKMLKIW 216
Score = 46.8 bits (106), Expect = 9e-05
Identities = 36/129 (27%), Positives = 57/129 (44%), Gaps = 7/129 (5%)
Frame = +2
Query: 152 HNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSS 331
H+ W++ I ++ IL+ S DKT +W L G + GH+ + DV
Sbjct: 100 HDDWISSIKGAEEW---ILTGSYDKTSRIWSLE------GKSIMTIVGHTDVVKDVAWVK 150
Query: 332 DGNYA---LSGSWDKTLRLWDLAAG----KTTRRFEDHTKDVLSVAFSVDNRQIVSGSRD 490
+ + LS S D+T+ LW+ K H V S+A + SGS D
Sbjct: 151 KDSLSCLLLSASMDQTILLWEWNVERNKVKALHCCRGHAGSVDSIAVDGSGTKFCSGSWD 210
Query: 491 KTIKLWNTL 517
K +K+W+T+
Sbjct: 211 KMLKIWSTV 219
Score = 35.9 bits (79), Expect = 0.17
Identities = 27/98 (27%), Positives = 41/98 (41%)
Frame = +2
Query: 80 RESSLFKPFSKMSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDE 259
R L+ P +K + L +L H GWVT + +P + ++S S D + +W D
Sbjct: 319 RHIRLWDPRTKDGSLVSL--SLTSHTGWVTSVKWSPTHEQQLISGSLDNIVKLW----DT 372
Query: 260 NNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTL 373
+ P L H + V + G LSG D L
Sbjct: 373 RSCKAPLYDLAAHEDKVLSVDWTDTG-LLLSGGADNKL 409
>AK001667-1|BAA91822.1| 513|Homo sapiens protein ( Homo sapiens
cDNA FLJ10805 fis, clone NT2RP4000839, weakly similar to
VEGETATIBLE INCOMPATIBILITY PROTEIN HET-E-1. ).
Length = 513
Score = 77.4 bits (182), Expect = 6e-14
Identities = 44/170 (25%), Positives = 79/170 (46%), Gaps = 8/170 (4%)
Frame = +2
Query: 290 YGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKD--------VLSV 445
+G + S DG Y ++GS D + +W+ GK + + +D VL +
Sbjct: 211 FGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCM 270
Query: 446 AFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWD 625
FS D + +G++D IK+W + + HS V+C+ FS + + I+S +D
Sbjct: 271 CFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQ--ILSASFD 328
Query: 626 RTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
+T+++ L + K GHS ++N T + DG S D +W++
Sbjct: 329 QTIRIHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNM 378
Score = 68.1 bits (159), Expect = 3e-11
Identities = 52/204 (25%), Positives = 90/204 (44%), Gaps = 7/204 (3%)
Frame = +2
Query: 197 DMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLR 376
+M+ + ++D + VWK+ + ++ HS ++ + S D + LS S+D+T+R
Sbjct: 277 EMLATGAQDGKIKVWKIQSGQ----CLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIR 332
Query: 377 LWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN-TLAECKYTIQDDGH 553
+ L +GKT + F H+ V F+ D I+S S D T+K+WN EC T + G
Sbjct: 333 IHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFKSLGS 392
Query: 554 SD----WVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLG--HSGYLNTVTVS 715
+ V+ V P + +V C TV + ++ ++ G G +S
Sbjct: 393 TAGTDITVNSVILLPKNPEHFVV-CNRSNTVVIMNMQGQIVRSFSSGKREGGDFVCCALS 451
Query: 716 PDGSLCASGGKDMXAMLWDLNDGK 787
P G G+D + GK
Sbjct: 452 PRGEWIYCVGEDFVLYCFSTVTGK 475
Score = 43.2 bits (97), Expect = 0.001
Identities = 34/134 (25%), Positives = 53/134 (39%)
Frame = +2
Query: 107 SKMSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKR 286
++ S T K G+ G + V + PK P+ + +R T+++ + KR
Sbjct: 381 TECSNTFKSLGSTAGTDITVNSVILLPKNPEHFVVCNRSNTVVIMNMQGQIVRSFSSGKR 440
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNR 466
G F+ LS G + D L + GK R H KDV+ +A
Sbjct: 441 EGGD--FVC-CALSPRGEWIYCVGEDFVLYCFSTVTGKLERTLTVHEKDVIGIAHHPHQN 497
Query: 467 QIVSGSRDKTIKLW 508
I + S D +KLW
Sbjct: 498 PIATYSEDGLLKLW 511
>AF242546-1|AAF60355.1| 423|Homo sapiens YTM1 protein.
Length = 423
Score = 77.4 bits (182), Expect = 6e-14
Identities = 52/162 (32%), Positives = 80/162 (49%), Gaps = 3/162 (1%)
Frame = +2
Query: 275 PQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFS 454
P L GH +S V L SD S SWD T+R+WD+ +G + K +++S
Sbjct: 249 PIVTLSGHMEAVSSV-LWSDAEEICSASWDHTIRVWDVESGSLKSTLTGN-KVFNCISYS 306
Query: 455 VDNRQIVSGSRDKTIKLWN--TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR 628
+++ SGS D+ I+LW+ T ++ H+ WV+ V++SP H +I S D
Sbjct: 307 PLCKRLASGSTDRHIRLWDPRTKDGSMVSLSLTSHTGWVTSVKWSPTHEQQLI-SGSLDN 365
Query: 629 TVKVWHLTNCKLKINHL-GHSGYLNTVTVSPDGSLCASGGKD 751
VK+W +CK + L H + +V + D L SGG D
Sbjct: 366 IVKLWDTRSCKAPLYDLAAHEDKVLSVDWT-DTGLLLSGGAD 406
Score = 67.7 bits (158), Expect = 5e-11
Identities = 64/232 (27%), Positives = 97/232 (41%), Gaps = 9/232 (3%)
Frame = +2
Query: 104 FSKMSETLKLRG----TLRGHNGWVTQIATNPK--YPDMILSSSRDKTLIVWKLTRDENN 265
+ K S L G T+ GH V +A K ++LS+S D+T+++W+ + N
Sbjct: 119 YDKTSRIWSLEGKSIMTIVGHTDVVKDVAWVKKDSLSCLLLSASMDQTILLWEWNVERNK 178
Query: 266 YGIPQKRLY---GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDV 436
K L+ GH+ + + + G SGSWDK L++W E+ T
Sbjct: 179 V----KALHCCRGHAGSVDSIAVDGSGTKFCSGSWDKMLKIWSTVPTDEEDEMEEST--- 231
Query: 437 LSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSC 616
NR + KT +L T + GH + VS V +S I S
Sbjct: 232 --------NR---PRKKQKTEQLGLTRTP---IVTLSGHMEAVSSVLWSDAEE---ICSA 274
Query: 617 GWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
WD T++VW + + LK G+ + N ++ SP ASG D LWD
Sbjct: 275 SWDHTIRVWDVESGSLKSTLTGNKVF-NCISYSPLCKRLASGSTDRHIRLWD 325
Score = 48.0 bits (109), Expect = 4e-05
Identities = 30/105 (28%), Positives = 56/105 (53%), Gaps = 5/105 (4%)
Frame = +2
Query: 470 IVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRF-SPNHANPIIVSCGWDRTVKVW- 643
I++GS DKT ++W+ + TI GH+D V V + + + +++S D+T+ +W
Sbjct: 114 ILTGSYDKTSRIWSLEGKSIMTIV--GHTDVVKDVAWVKKDSLSCLLLSASMDQTILLWE 171
Query: 644 -HLTNCKLKINHL--GHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
++ K+K H GH+G ++++ V G+ SG D +W
Sbjct: 172 WNVERNKVKALHCCRGHAGSVDSIAVDGSGTKFCSGSWDKMLKIW 216
Score = 46.8 bits (106), Expect = 9e-05
Identities = 36/129 (27%), Positives = 57/129 (44%), Gaps = 7/129 (5%)
Frame = +2
Query: 152 HNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSS 331
H+ W++ I ++ IL+ S DKT +W L G + GH+ + DV
Sbjct: 100 HDDWISSIKGAEEW---ILTGSYDKTSRIWSLE------GKSIMTIVGHTDVVKDVAWVK 150
Query: 332 DGNYA---LSGSWDKTLRLWDLAAG----KTTRRFEDHTKDVLSVAFSVDNRQIVSGSRD 490
+ + LS S D+T+ LW+ K H V S+A + SGS D
Sbjct: 151 KDSLSCLLLSASMDQTILLWEWNVERNKVKALHCCRGHAGSVDSIAVDGSGTKFCSGSWD 210
Query: 491 KTIKLWNTL 517
K +K+W+T+
Sbjct: 211 KMLKIWSTV 219
Score = 35.9 bits (79), Expect = 0.17
Identities = 27/98 (27%), Positives = 41/98 (41%)
Frame = +2
Query: 80 RESSLFKPFSKMSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDE 259
R L+ P +K + L +L H GWVT + +P + ++S S D + +W D
Sbjct: 319 RHIRLWDPRTKDGSMVSL--SLTSHTGWVTSVKWSPTHEQQLISGSLDNIVKLW----DT 372
Query: 260 NNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTL 373
+ P L H + V + G LSG D L
Sbjct: 373 RSCKAPLYDLAAHEDKVLSVDWTDTG-LLLSGGADNKL 409
>X04526-2|CAA28207.1| 340|Homo sapiens protein ( Human liver mRNA
for beta-subunit signal transducing proteins Gs/Gi
(beta-G). ).
Length = 340
Score = 77.0 bits (181), Expect = 7e-14
Identities = 57/209 (27%), Positives = 93/209 (44%), Gaps = 3/209 (1%)
Frame = +2
Query: 155 NGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSD 334
+ WV A P + + D ++ L E N + + L GH+ ++S D
Sbjct: 97 SSWVMTCAYAPS-GNYVACGGLDNICSIYNLKTREGNVRV-SRELAGHTGYLSCCRFLDD 154
Query: 335 GNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNT 514
N ++ S D T LWD+ G+ T F HT DV+S++ + D R VSG+ D + KLW+
Sbjct: 155 -NQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDV 213
Query: 515 L-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK--LKINHLGH 685
C+ T GH ++ + F PN N D T +++ L + + +H
Sbjct: 214 REGMCRQTF--TGHESDINAICFFPN-GNAFATGSD-DATCRLFDLRADQELMTYSHDNI 269
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ +V+ S G L +G D +WD
Sbjct: 270 ICGITSVSFSKSGRLLLAGYDDFNCNVWD 298
Score = 74.9 bits (176), Expect = 3e-13
Identities = 57/227 (25%), Positives = 99/227 (43%), Gaps = 4/227 (1%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSH 304
++ R TLRGH + + +++S+S+D LI+W + IP + S
Sbjct: 45 MRTRRTLRGHLAKIYAMHWGTD-SRLLVSASQDGKLIIWDSYTTNKVHAIPLR-----SS 98
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAG----KTTRRFEDHTKDVLSVAFSVDNRQI 472
++ + GNY G D +++L + +R HT LS +D+ QI
Sbjct: 99 WVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHT-GYLSCCRFLDDNQI 157
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
V+ S D T LW+ + + T GH+ V + +P+ + VS D + K+W +
Sbjct: 158 VTSSGDTTCALWD-IETGQQTTTFTGHTGDVMSLSLAPD--TRLFVSGACDASAKLWDVR 214
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ GH +N + P+G+ A+G D L+DL + L
Sbjct: 215 EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQEL 261
Score = 64.9 bits (151), Expect = 3e-10
Identities = 49/212 (23%), Positives = 91/212 (42%), Gaps = 2/212 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH G+++ + I++SS D T +W + + GH+ + +
Sbjct: 139 LAGHTGYLS--CCRFLDDNQIVTSSGDTTCALWDIETGQQT-----TTFTGHTGDVMSLS 191
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
L+ D +SG+ D + +LWD+ G + F H D+ ++ F + +GS D T +
Sbjct: 192 LAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCR 251
Query: 503 LWNTLAECKY-TIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR-TVKVWHLTNCKLKINH 676
L++ A+ + T D ++ V FS + ++ G+D VW
Sbjct: 252 LFDLRADQELMTYSHDNIICGITSVSFSKSGR---LLLAGYDDFNCNVWDALKADRAGVL 308
Query: 677 LGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
GH ++ + V+ DG A+G D +W+
Sbjct: 309 AGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>M36430-1|AAA63265.1| 247|Homo sapiens protein ( Human transducin
beta-1 subunit mRNA, 3' end. ).
Length = 247
Score = 77.0 bits (181), Expect = 7e-14
Identities = 57/209 (27%), Positives = 93/209 (44%), Gaps = 3/209 (1%)
Frame = +2
Query: 155 NGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSD 334
+ WV A P + + D ++ L E N + + L GH+ ++S D
Sbjct: 4 SSWVMTCAYAPS-GNYVACGGLDNICSIYNLKTREGNVRV-SRELAGHTGYLSCCRFLDD 61
Query: 335 GNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNT 514
N ++ S D T LWD+ G+ T F HT DV+S++ + D R VSG+ D + KLW+
Sbjct: 62 -NQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDV 120
Query: 515 L-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK--LKINHLGH 685
C+ T GH ++ + F PN N D T +++ L + + +H
Sbjct: 121 REGMCRQTF--TGHESDINAICFFPN-GNAFATGSD-DATCRLFDLRADQELMTYSHDNI 176
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ +V+ S G L +G D +WD
Sbjct: 177 ICGITSVSFSKSGRLLLAGYDDFNCNVWD 205
Score = 64.9 bits (151), Expect = 3e-10
Identities = 49/212 (23%), Positives = 91/212 (42%), Gaps = 2/212 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH G+++ + I++SS D T +W + + GH+ + +
Sbjct: 46 LAGHTGYLS--CCRFLDDNQIVTSSGDTTCALWDIETGQQT-----TTFTGHTGDVMSLS 98
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
L+ D +SG+ D + +LWD+ G + F H D+ ++ F + +GS D T +
Sbjct: 99 LAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCR 158
Query: 503 LWNTLAECKY-TIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR-TVKVWHLTNCKLKINH 676
L++ A+ + T D ++ V FS + ++ G+D VW
Sbjct: 159 LFDLRADQELMTYSHDNIICGITSVSFSKSGR---LLLAGYDDFNCNVWDALKADRAGVL 215
Query: 677 LGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
GH ++ + V+ DG A+G D +W+
Sbjct: 216 AGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 247
Score = 61.7 bits (143), Expect = 3e-09
Identities = 43/169 (25%), Positives = 73/169 (43%), Gaps = 4/169 (2%)
Frame = +2
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAG----KTTRRFEDHTKDVLSVAFSVDNR 466
S ++ + GNY G D +++L + +R HT LS +D+
Sbjct: 4 SSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHT-GYLSCCRFLDDN 62
Query: 467 QIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWH 646
QIV+ S D T LW+ + + T GH+ V + +P+ + VS D + K+W
Sbjct: 63 QIVTSSGDTTCALWD-IETGQQTTTFTGHTGDVMSLSLAPD--TRLFVSGACDASAKLWD 119
Query: 647 LTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ + GH +N + P+G+ A+G D L+DL + L
Sbjct: 120 VREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQEL 168
>EF011617-1|ABK41107.1| 423|Homo sapiens CDW7/WDR12 protein.
Length = 423
Score = 77.0 bits (181), Expect = 7e-14
Identities = 52/162 (32%), Positives = 80/162 (49%), Gaps = 3/162 (1%)
Frame = +2
Query: 275 PQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFS 454
P L GH +S V L SD S SWD T+R+WD+ +G + K +++S
Sbjct: 249 PIVTLSGHMEAVSSV-LWSDAEEICSASWDHTIRVWDVESGSLKSTLTGN-KVFNCISYS 306
Query: 455 VDNRQIVSGSRDKTIKLWN--TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR 628
+++ SGS D+ I+LW+ T ++ H+ WV+ V++SP H +I S D
Sbjct: 307 PLCKRLASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLI-SGSLDN 365
Query: 629 TVKVWHLTNCKLKINHL-GHSGYLNTVTVSPDGSLCASGGKD 751
VK+W +CK + L H + +V + D L SGG D
Sbjct: 366 IVKLWDTRSCKAPLYDLAAHEDKVLSVDWT-DTGLLLSGGAD 406
Score = 67.7 bits (158), Expect = 5e-11
Identities = 64/232 (27%), Positives = 97/232 (41%), Gaps = 9/232 (3%)
Frame = +2
Query: 104 FSKMSETLKLRG----TLRGHNGWVTQIATNPK--YPDMILSSSRDKTLIVWKLTRDENN 265
+ K S L G T+ GH V +A K ++LS+S D+T+++W+ + N
Sbjct: 119 YDKTSRIWSLEGKSIMTIVGHTDVVKDVAWVKKDSLSCLLLSASMDQTILLWEWNVERNK 178
Query: 266 YGIPQKRLY---GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDV 436
K L+ GH+ + + + G SGSWDK L++W E+ T
Sbjct: 179 V----KALHCCRGHAGSVDSIAVDGSGTKFCSGSWDKMLKIWSTVPTDEEDEMEEST--- 231
Query: 437 LSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSC 616
NR + KT +L T + GH + VS V +S I S
Sbjct: 232 --------NR---PRKKQKTEQLGLTRTP---IVTLSGHMEAVSSVLWSDAEE---ICSA 274
Query: 617 GWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
WD T++VW + + LK G+ + N ++ SP ASG D LWD
Sbjct: 275 SWDHTIRVWDVESGSLKSTLTGNKVF-NCISYSPLCKRLASGSTDRHIRLWD 325
Score = 48.0 bits (109), Expect = 4e-05
Identities = 30/105 (28%), Positives = 56/105 (53%), Gaps = 5/105 (4%)
Frame = +2
Query: 470 IVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRF-SPNHANPIIVSCGWDRTVKVW- 643
I++GS DKT ++W+ + TI GH+D V V + + + +++S D+T+ +W
Sbjct: 114 ILTGSYDKTSRIWSLEGKSIMTIV--GHTDVVKDVAWVKKDSLSCLLLSASMDQTILLWE 171
Query: 644 -HLTNCKLKINHL--GHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
++ K+K H GH+G ++++ V G+ SG D +W
Sbjct: 172 WNVERNKVKALHCCRGHAGSVDSIAVDGSGTKFCSGSWDKMLKIW 216
Score = 46.8 bits (106), Expect = 9e-05
Identities = 36/129 (27%), Positives = 57/129 (44%), Gaps = 7/129 (5%)
Frame = +2
Query: 152 HNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSS 331
H+ W++ I ++ IL+ S DKT +W L G + GH+ + DV
Sbjct: 100 HDDWISSIKGAEEW---ILTGSYDKTSRIWSLE------GKSIMTIVGHTDVVKDVAWVK 150
Query: 332 DGNYA---LSGSWDKTLRLWDLAAG----KTTRRFEDHTKDVLSVAFSVDNRQIVSGSRD 490
+ + LS S D+T+ LW+ K H V S+A + SGS D
Sbjct: 151 KDSLSCLLLSASMDQTILLWEWNVERNKVKALHCCRGHAGSVDSIAVDGSGTKFCSGSWD 210
Query: 491 KTIKLWNTL 517
K +K+W+T+
Sbjct: 211 KMLKIWSTV 219
Score = 35.9 bits (79), Expect = 0.17
Identities = 27/98 (27%), Positives = 41/98 (41%)
Frame = +2
Query: 80 RESSLFKPFSKMSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDE 259
R L+ P +K + L +L H GWVT + +P + ++S S D + +W D
Sbjct: 319 RHIRLWDPRTKDGSLVSL--SLTSHTGWVTSVKWSPTHEQQLISGSLDNIVKLW----DT 372
Query: 260 NNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTL 373
+ P L H + V + G LSG D L
Sbjct: 373 RSCKAPLYDLAAHEDKVLSVDWTDTG-LLLSGGADNKL 409
>CR456784-1|CAG33065.1| 340|Homo sapiens GNB1 protein.
Length = 340
Score = 77.0 bits (181), Expect = 7e-14
Identities = 57/209 (27%), Positives = 93/209 (44%), Gaps = 3/209 (1%)
Frame = +2
Query: 155 NGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSD 334
+ WV A P + + D ++ L E N + + L GH+ ++S D
Sbjct: 97 SSWVMTCAYAPS-GNYVACGGLDNICSIYNLKTREGNVRV-SRELAGHTGYLSCCRFLDD 154
Query: 335 GNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNT 514
N ++ S D T LWD+ G+ T F HT DV+S++ + D R VSG+ D + KLW+
Sbjct: 155 -NQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDV 213
Query: 515 L-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK--LKINHLGH 685
C+ T GH ++ + F PN N D T +++ L + + +H
Sbjct: 214 REGMCRQTF--TGHESDINAICFFPN-GNAFATGSD-DATCRLFDLRADQELMTYSHDNI 269
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ +V+ S G L +G D +WD
Sbjct: 270 ICGITSVSFSKSGRLLLAGYDDFNCNVWD 298
Score = 74.9 bits (176), Expect = 3e-13
Identities = 57/227 (25%), Positives = 99/227 (43%), Gaps = 4/227 (1%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSH 304
++ R TLRGH + + +++S+S+D LI+W + IP + S
Sbjct: 45 MRTRRTLRGHLAKIYAMHWGTD-SRLLVSASQDGKLIIWDSYTTNKVHAIPLR-----SS 98
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAG----KTTRRFEDHTKDVLSVAFSVDNRQI 472
++ + GNY G D +++L + +R HT LS +D+ QI
Sbjct: 99 WVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHT-GYLSCCRFLDDNQI 157
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
V+ S D T LW+ + + T GH+ V + +P+ + VS D + K+W +
Sbjct: 158 VTSSGDTTCALWD-IETGQQTTTFTGHTGDVMSLSLAPD--TRLFVSGACDASAKLWDVR 214
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ GH +N + P+G+ A+G D L+DL + L
Sbjct: 215 EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQEL 261
Score = 64.9 bits (151), Expect = 3e-10
Identities = 49/212 (23%), Positives = 91/212 (42%), Gaps = 2/212 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH G+++ + I++SS D T +W + + GH+ + +
Sbjct: 139 LAGHTGYLS--CCRFLDDNQIVTSSGDTTCALWDIETGQQT-----TTFTGHTGDVMSLS 191
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
L+ D +SG+ D + +LWD+ G + F H D+ ++ F + +GS D T +
Sbjct: 192 LAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCR 251
Query: 503 LWNTLAECKY-TIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR-TVKVWHLTNCKLKINH 676
L++ A+ + T D ++ V FS + ++ G+D VW
Sbjct: 252 LFDLRADQELMTYSHDNIICGITSVSFSKSGR---LLLAGYDDFNCNVWDALKADRAGVL 308
Query: 677 LGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
GH ++ + V+ DG A+G D +W+
Sbjct: 309 AGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>BT007305-1|AAP35969.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 340
Score = 77.0 bits (181), Expect = 7e-14
Identities = 57/209 (27%), Positives = 93/209 (44%), Gaps = 3/209 (1%)
Frame = +2
Query: 155 NGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSD 334
+ WV A P + + D ++ L E N + + L GH+ ++S D
Sbjct: 97 SSWVMTCAYAPS-GNYVACGGLDNICSIYNLKTREGNVRV-SRELAGHTGYLSCCRFLDD 154
Query: 335 GNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNT 514
N ++ S D T LWD+ G+ T F HT DV+S++ + D R VSG+ D + KLW+
Sbjct: 155 -NQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDV 213
Query: 515 L-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK--LKINHLGH 685
C+ T GH ++ + F PN N D T +++ L + + +H
Sbjct: 214 REGMCRQTF--TGHESDINAICFFPN-GNAFATGSD-DATCRLFDLRADQELMTYSHDNI 269
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ +V+ S G L +G D +WD
Sbjct: 270 ICGITSVSFSKSGRLLLAGYDDFNCNVWD 298
Score = 74.9 bits (176), Expect = 3e-13
Identities = 57/227 (25%), Positives = 99/227 (43%), Gaps = 4/227 (1%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSH 304
++ R TLRGH + + +++S+S+D LI+W + IP + S
Sbjct: 45 MRTRRTLRGHLAKIYAMHWGTD-SRLLVSASQDGKLIIWDSYTTNKVHAIPLR-----SS 98
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAG----KTTRRFEDHTKDVLSVAFSVDNRQI 472
++ + GNY G D +++L + +R HT LS +D+ QI
Sbjct: 99 WVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHT-GYLSCCRFLDDNQI 157
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
V+ S D T LW+ + + T GH+ V + +P+ + VS D + K+W +
Sbjct: 158 VTSSGDTTCALWD-IETGQQTTTFTGHTGDVMSLSLAPD--TRLFVSGACDASAKLWDVR 214
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ GH +N + P+G+ A+G D L+DL + L
Sbjct: 215 EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQEL 261
Score = 64.9 bits (151), Expect = 3e-10
Identities = 49/212 (23%), Positives = 91/212 (42%), Gaps = 2/212 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH G+++ + I++SS D T +W + + GH+ + +
Sbjct: 139 LAGHTGYLS--CCRFLDDNQIVTSSGDTTCALWDIETGQQT-----TTFTGHTGDVMSLS 191
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
L+ D +SG+ D + +LWD+ G + F H D+ ++ F + +GS D T +
Sbjct: 192 LAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCR 251
Query: 503 LWNTLAECKY-TIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR-TVKVWHLTNCKLKINH 676
L++ A+ + T D ++ V FS + ++ G+D VW
Sbjct: 252 LFDLRADQELMTYSHDNIICGITSVSFSKSGR---LLLAGYDDFNCNVWDALKADRAGVL 308
Query: 677 LGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
GH ++ + V+ DG A+G D +W+
Sbjct: 309 AGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>BC114618-1|AAI14619.1| 332|Homo sapiens GNB1 protein protein.
Length = 332
Score = 77.0 bits (181), Expect = 7e-14
Identities = 57/209 (27%), Positives = 93/209 (44%), Gaps = 3/209 (1%)
Frame = +2
Query: 155 NGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSD 334
+ WV A P + + D ++ L E N + + L GH+ ++S D
Sbjct: 97 SSWVMTCAYAPS-GNYVACGGLDNICSIYNLKTREGNVRV-SRELAGHTGYLSCCRFLDD 154
Query: 335 GNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNT 514
N ++ S D T LWD+ G+ T F HT DV+S++ + D R VSG+ D + KLW+
Sbjct: 155 -NQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDV 213
Query: 515 L-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK--LKINHLGH 685
C+ T GH ++ + F PN N D T +++ L + + +H
Sbjct: 214 REGMCRQTF--TGHESDINAICFFPN-GNAFATGSD-DATCRLFDLRADQELMTYSHDNI 269
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ +V+ S G L +G D +WD
Sbjct: 270 ICGITSVSFSKSGRLLLAGYDDFNCNVWD 298
Score = 74.9 bits (176), Expect = 3e-13
Identities = 57/227 (25%), Positives = 99/227 (43%), Gaps = 4/227 (1%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSH 304
++ R TLRGH + + +++S+S+D LI+W + IP + S
Sbjct: 45 MRTRRTLRGHLAKIYAMHWGTD-SRLLVSASQDGKLIIWDSYTTNKVHAIPLR-----SS 98
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAG----KTTRRFEDHTKDVLSVAFSVDNRQI 472
++ + GNY G D +++L + +R HT LS +D+ QI
Sbjct: 99 WVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHT-GYLSCCRFLDDNQI 157
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
V+ S D T LW+ + + T GH+ V + +P+ + VS D + K+W +
Sbjct: 158 VTSSGDTTCALWD-IETGQQTTTFTGHTGDVMSLSLAPD--TRLFVSGACDASAKLWDVR 214
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ GH +N + P+G+ A+G D L+DL + L
Sbjct: 215 EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQEL 261
>BC035409-1|AAH35409.1| 808|Homo sapiens transducin (beta)-like 3
protein.
Length = 808
Score = 77.0 bits (181), Expect = 7e-14
Identities = 55/214 (25%), Positives = 101/214 (47%), Gaps = 18/214 (8%)
Frame = +2
Query: 200 MILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSS-DGNYALSGSWDKTLR 376
+ S ++D+++ +W++ + + Q GH+H + V S ++ ++GS D T++
Sbjct: 390 LFASCAKDQSVRIWRMNKAGQVMCVAQGS--GHTHSVGTVCCSRLKESFLVTGSQDCTVK 447
Query: 377 LWDLAAG-----------------KTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKL 505
LW L +TT+R H KD+ SVA + +++ + +GS+D+T KL
Sbjct: 448 LWPLPKALLSKNTAPDNGPILLQAQTTQRC--HDKDINSVAIAPNDKLLATGSQDRTAKL 505
Query: 506 WNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGH 685
W L +C+ GH + CV+FSP + ++ + D T+K+W L + GH
Sbjct: 506 W-ALPQCQLLGVFSGHRRGLWCVQFSP--MDQVLATASADGTIKLWALQDFSCLKTFEGH 562
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGK 787
+ V G+ S G D LW + + +
Sbjct: 563 DASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNE 596
Score = 57.6 bits (133), Expect = 5e-08
Identities = 38/152 (25%), Positives = 63/152 (41%), Gaps = 1/152 (0%)
Frame = +2
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFED-HTKDVLSVAFSVDNRQIVSGSRDKTI 499
LS D ++ S L W G TR + HT V ++AF + + +G D +
Sbjct: 74 LSPDNEVLVTASRALLLAQWAWQEGSVTRLSKAIHTAPVATMAFDPTSTLLATGGCDGAV 133
Query: 500 KLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
++W+ + T G V V F P+ ++ S D ++VW L +
Sbjct: 134 RVWDIVRHYG-THHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWSLQDRSCLAVLT 192
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
H + ++ S DG S G+D ++WDL
Sbjct: 193 AHYSAVTSLAFSADGHTMLSSGRDKICIIWDL 224
Score = 55.2 bits (127), Expect = 3e-07
Identities = 51/183 (27%), Positives = 82/183 (44%), Gaps = 18/183 (9%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDL-AAGKT--TRRFEDHTKDVLSVAFS- 454
L+GH+ + + + G S + D+++R+W + AG+ + HT V +V S
Sbjct: 372 LHGHTDIVLALDVFRKGWLFASCAKDQSVRIWRMNKAGQVMCVAQGSGHTHSVGTVCCSR 431
Query: 455 VDNRQIVSGSRDKTIKLWNTLAEC--KYTIQDDG------------HSDWVSCVRFSPNH 592
+ +V+GS+D T+KLW K T D+G H ++ V +PN
Sbjct: 432 LKESFLVTGSQDCTVKLWPLPKALLSKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPN- 490
Query: 593 ANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ ++ + DRT K+W L C+L GH L V SP + A+ D LW
Sbjct: 491 -DKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLATASADGTIKLWA 549
Query: 773 LND 781
L D
Sbjct: 550 LQD 552
Score = 54.0 bits (124), Expect = 6e-07
Identities = 52/217 (23%), Positives = 88/217 (40%), Gaps = 10/217 (4%)
Frame = +2
Query: 149 GHNGWVTQIATNPKYPDMILSSSRDKTLIVWKL--------TRDENNYGIPQKRLYGHSH 304
GH V + + +++ S+D T+ +W L T +N + Q + H
Sbjct: 419 GHTHSVGTVCCSRLKESFLVTGSQDCTVKLWPLPKALLSKNTAPDNGPILLQAQTTQRCH 478
Query: 305 F--ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVS 478
I+ V ++ + +GS D+T +LW L + F H + + V FS ++ + +
Sbjct: 479 DKDINSVAIAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLAT 538
Query: 479 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 658
S D TIKLW L + +GH V V F ++S G D VK+W + N
Sbjct: 539 ASADGTIKLW-ALQDFSCLKTFEGHDASVLKVAFVSRGTQ--LLSSGSDGLVKLWTIKNN 595
Query: 659 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
+ H + + S +G D +LW
Sbjct: 596 ECVRTLDAHEDKVWGLHCSRLDDHALTGASDSRVILW 632
Score = 53.2 bits (122), Expect = 1e-06
Identities = 54/220 (24%), Positives = 95/220 (43%), Gaps = 8/220 (3%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIP-----QKRLYGHSHF 307
L H VT +A + M LSS RDK I+W L + +P + +
Sbjct: 191 LTAHYSAVTSLAFSADGHTM-LSSGRDKICIIWDLQSCQATRTVPVFESVEAAVLLPEEP 249
Query: 308 ISDVVLSSDGNYALSGSWDKTLRLWDLAAGK---TTRRFEDHTKDVLSVAFSVDNRQIVS 478
+S + + S G Y L+ TLR+W+ A+G+ T + +++ + +++
Sbjct: 250 VSQLGVKSPGLYFLTAGDQGTLRVWEAASGQCVYTQAQPPGPGQELTHCTLAHTAGVVLT 309
Query: 479 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 658
+ D + L+ + Q G+S+ V VRF + ++V+ +KV+ L
Sbjct: 310 ATADHNLLLYEA-RSLRLQKQFAGYSEEVLDVRFLGPEDSHVVVASN-SPCLKVFELQTS 367
Query: 659 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLN 778
+I H GH+ + + V G L AS KD +W +N
Sbjct: 368 ACQILH-GHTDIVLALDVFRKGWLFASCAKDQSVRIWRMN 406
Score = 41.5 bits (93), Expect = 0.003
Identities = 30/134 (22%), Positives = 56/134 (41%)
Frame = +2
Query: 128 KLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHF 307
+L G GH + + +P ++ ++S D T+ +W L ++ K GH
Sbjct: 512 QLLGVFSGHRRGLWCVQFSPM-DQVLATASADGTIKLWAL----QDFSC-LKTFEGHDAS 565
Query: 308 ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSR 487
+ V S G LS D ++LW + + R + H V + S + ++G+
Sbjct: 566 VLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAHEDKVWGLHCSRLDDHALTGAS 625
Query: 488 DKTIKLWNTLAECK 529
D + LW + E +
Sbjct: 626 DSRVILWKDVTEAE 639
Score = 40.7 bits (91), Expect = 0.006
Identities = 28/89 (31%), Positives = 45/89 (50%), Gaps = 1/89 (1%)
Frame = +2
Query: 146 RGHNGWVTQIATNPKYPDMIL-SSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
RG G V +A +P ++L SS+ D + VW L +D + + L H ++ +
Sbjct: 148 RGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWSL-QDRSCLAV----LTAHYSAVTSLA 202
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTR 409
S+DG+ LS DK +WDL + + TR
Sbjct: 203 FSADGHTMLSSGRDKICIIWDLQSCQATR 231
Score = 37.9 bits (84), Expect = 0.042
Identities = 28/124 (22%), Positives = 53/124 (42%), Gaps = 2/124 (1%)
Frame = +2
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H+ ++ + +G D +R+WD+ T F V VAF D +++
Sbjct: 108 HTAPVATMAFDPTSTLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLL 167
Query: 476 --SGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 649
S + D I++W +L + H V+ + FS + ++S G D+ +W L
Sbjct: 168 LFSSATDAAIRVW-SLQDRSCLAVLTAHYSAVTSLAFSAD--GHTMLSSGRDKICIIWDL 224
Query: 650 TNCK 661
+C+
Sbjct: 225 QSCQ 228
>BC021110-1|AAH21110.1| 421|Homo sapiens WD repeat and SOCS
box-containing 1 protein.
Length = 421
Score = 77.0 bits (181), Expect = 7e-14
Identities = 42/139 (30%), Positives = 70/139 (50%), Gaps = 1/139 (0%)
Frame = +2
Query: 371 LRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI-VSGSRDKTIKLWNTLAECKYTIQDD 547
+++WD+ GK DHT+ V + F+ D I VS SRDKT+++W+ +
Sbjct: 152 IKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKVLR 211
Query: 548 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 727
GH +WV FSP+ + ++ S G + V +W++ + GH + SPDG+
Sbjct: 212 GHQNWVYSCAFSPDSS--MLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVACDFSPDGA 269
Query: 728 LCASGGKDMXAMLWDLNDG 784
L A+ D +WD ++G
Sbjct: 270 LLATASYDTRVYIWDPHNG 288
Score = 67.7 bits (158), Expect = 5e-11
Identities = 64/229 (27%), Positives = 99/229 (43%), Gaps = 13/229 (5%)
Frame = +2
Query: 122 TLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHS 301
T KL L H V + P +++S+SRDKTL VW L +D+ N K L GH
Sbjct: 159 TGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDL-KDDGNM---MKVLRGHQ 214
Query: 302 HFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSG 481
+++ S D + S K + LW++ R+ E H DV++ FS D + +
Sbjct: 215 NWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVACDFSPDGALLATA 274
Query: 482 SRDKTIKLW-----NTLAECKY------TIQDDGHSD-WVSCVRFSPNHANPIIVSCGWD 625
S D + +W + L E + I G +D WV V FS H + S D
Sbjct: 275 SYDTRVYIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSFS--HDGLHVASLADD 332
Query: 626 RTVKVWHL-TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
+ V+ W + + +++ L + S DGS+ A+G D W
Sbjct: 333 KMVRFWRIDEDYPVQVAPLSNG---LCCAFSTDGSVLAAGTHDGSVYFW 378
>BC014007-1|AAH14007.1| 808|Homo sapiens TBL3 protein protein.
Length = 808
Score = 77.0 bits (181), Expect = 7e-14
Identities = 55/214 (25%), Positives = 101/214 (47%), Gaps = 18/214 (8%)
Frame = +2
Query: 200 MILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSS-DGNYALSGSWDKTLR 376
+ S ++D+++ +W++ + + Q GH+H + V S ++ ++GS D T++
Sbjct: 390 LFASCAKDQSVRIWRMNKAGQVMCVAQGS--GHTHSVGTVCCSRLKESFLVTGSQDCTVK 447
Query: 377 LWDLAAG-----------------KTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKL 505
LW L +TT+R H KD+ SVA + +++ + +GS+D+T KL
Sbjct: 448 LWPLPKALLSKNTAPDNGPILLQAQTTQRC--HDKDINSVAIAPNDKLLATGSQDRTAKL 505
Query: 506 WNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGH 685
W L +C+ GH + CV+FSP + ++ + D T+K+W L + GH
Sbjct: 506 W-ALPQCQLLGVFSGHRRGLWCVQFSP--MDQVLATASADGTIKLWALQDFSCLKTFEGH 562
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGK 787
+ V G+ S G D LW + + +
Sbjct: 563 DASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNE 596
Score = 58.8 bits (136), Expect = 2e-08
Identities = 38/152 (25%), Positives = 64/152 (42%), Gaps = 1/152 (0%)
Frame = +2
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFED-HTKDVLSVAFSVDNRQIVSGSRDKTI 499
LS D ++ S L W G TR ++ HT V ++AF + + +G D +
Sbjct: 74 LSPDNEVLVTASRALLLAQWAWQEGSVTRLWKAIHTAPVATMAFDPTSTLLATGGCDGAV 133
Query: 500 KLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
++W+ + T G V V F P+ ++ S D ++VW L +
Sbjct: 134 RVWDIVRHYG-THHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWSLQDRSCLAVLT 192
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
H + ++ S DG S G+D ++WDL
Sbjct: 193 AHYSAVTSLAFSADGHTMLSSGRDKICIIWDL 224
Score = 55.2 bits (127), Expect = 3e-07
Identities = 51/183 (27%), Positives = 82/183 (44%), Gaps = 18/183 (9%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDL-AAGKT--TRRFEDHTKDVLSVAFS- 454
L+GH+ + + + G S + D+++R+W + AG+ + HT V +V S
Sbjct: 372 LHGHTDIVLALDVFRKGWLFASCAKDQSVRIWRMNKAGQVMCVAQGSGHTHSVGTVCCSR 431
Query: 455 VDNRQIVSGSRDKTIKLWNTLAEC--KYTIQDDG------------HSDWVSCVRFSPNH 592
+ +V+GS+D T+KLW K T D+G H ++ V +PN
Sbjct: 432 LKESFLVTGSQDCTVKLWPLPKALLSKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPN- 490
Query: 593 ANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ ++ + DRT K+W L C+L GH L V SP + A+ D LW
Sbjct: 491 -DKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLATASADGTIKLWA 549
Query: 773 LND 781
L D
Sbjct: 550 LQD 552
Score = 54.0 bits (124), Expect = 6e-07
Identities = 52/217 (23%), Positives = 88/217 (40%), Gaps = 10/217 (4%)
Frame = +2
Query: 149 GHNGWVTQIATNPKYPDMILSSSRDKTLIVWKL--------TRDENNYGIPQKRLYGHSH 304
GH V + + +++ S+D T+ +W L T +N + Q + H
Sbjct: 419 GHTHSVGTVCCSRLKESFLVTGSQDCTVKLWPLPKALLSKNTAPDNGPILLQAQTTQRCH 478
Query: 305 F--ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVS 478
I+ V ++ + +GS D+T +LW L + F H + + V FS ++ + +
Sbjct: 479 DKDINSVAIAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLAT 538
Query: 479 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 658
S D TIKLW L + +GH V V F ++S G D VK+W + N
Sbjct: 539 ASADGTIKLW-ALQDFSCLKTFEGHDASVLKVAFVSRGTQ--LLSSGSDGLVKLWTIKNN 595
Query: 659 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
+ H + + S +G D +LW
Sbjct: 596 ECVRTLDAHEDKVWGLHCSRLDDHALTGASDSRVILW 632
Score = 53.2 bits (122), Expect = 1e-06
Identities = 54/220 (24%), Positives = 95/220 (43%), Gaps = 8/220 (3%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIP-----QKRLYGHSHF 307
L H VT +A + M LSS RDK I+W L + +P + +
Sbjct: 191 LTAHYSAVTSLAFSADGHTM-LSSGRDKICIIWDLQSCQATRTVPVFESVEAAVLLPEEP 249
Query: 308 ISDVVLSSDGNYALSGSWDKTLRLWDLAAGK---TTRRFEDHTKDVLSVAFSVDNRQIVS 478
+S + + S G Y L+ TLR+W+ A+G+ T + +++ + +++
Sbjct: 250 VSQLGVKSPGLYFLTAGDQGTLRVWEAASGQCVYTQAQPPGPGQELTHCTLAHTAGVVLT 309
Query: 479 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 658
+ D + L+ + Q G+S+ V VRF + ++V+ +KV+ L
Sbjct: 310 ATADHNLLLYEA-RSLRLQKQFAGYSEEVLDVRFLGPEDSHVVVASN-SPCLKVFELQTS 367
Query: 659 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLN 778
+I H GH+ + + V G L AS KD +W +N
Sbjct: 368 ACQILH-GHTDIVLALDVFRKGWLFASCAKDQSVRIWRMN 406
Score = 41.5 bits (93), Expect = 0.003
Identities = 30/134 (22%), Positives = 56/134 (41%)
Frame = +2
Query: 128 KLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHF 307
+L G GH + + +P ++ ++S D T+ +W L ++ K GH
Sbjct: 512 QLLGVFSGHRRGLWCVQFSPM-DQVLATASADGTIKLWAL----QDFSC-LKTFEGHDAS 565
Query: 308 ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSR 487
+ V S G LS D ++LW + + R + H V + S + ++G+
Sbjct: 566 VLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAHEDKVWGLHCSRLDDHALTGAS 625
Query: 488 DKTIKLWNTLAECK 529
D + LW + E +
Sbjct: 626 DSRVILWKDVTEAE 639
Score = 40.7 bits (91), Expect = 0.006
Identities = 28/89 (31%), Positives = 45/89 (50%), Gaps = 1/89 (1%)
Frame = +2
Query: 146 RGHNGWVTQIATNPKYPDMIL-SSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
RG G V +A +P ++L SS+ D + VW L +D + + L H ++ +
Sbjct: 148 RGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWSL-QDRSCLAV----LTAHYSAVTSLA 202
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTR 409
S+DG+ LS DK +WDL + + TR
Sbjct: 203 FSADGHTMLSSGRDKICIIWDLQSCQATR 231
Score = 37.9 bits (84), Expect = 0.042
Identities = 28/124 (22%), Positives = 53/124 (42%), Gaps = 2/124 (1%)
Frame = +2
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H+ ++ + +G D +R+WD+ T F V VAF D +++
Sbjct: 108 HTAPVATMAFDPTSTLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLL 167
Query: 476 --SGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 649
S + D I++W +L + H V+ + FS + ++S G D+ +W L
Sbjct: 168 LFSSATDAAIRVW-SLQDRSCLAVLTAHYSAVTSLAFSAD--GHTMLSSGRDKICIIWDL 224
Query: 650 TNCK 661
+C+
Sbjct: 225 QSCQ 228
>BC010231-1|AAH10231.1| 808|Homo sapiens transducin (beta)-like 3
protein.
Length = 808
Score = 77.0 bits (181), Expect = 7e-14
Identities = 55/214 (25%), Positives = 101/214 (47%), Gaps = 18/214 (8%)
Frame = +2
Query: 200 MILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSS-DGNYALSGSWDKTLR 376
+ S ++D+++ +W++ + + Q GH+H + V S ++ ++GS D T++
Sbjct: 390 LFASCAKDQSVRIWRMNKAGQVMCVAQGS--GHTHSVGTVCCSRLKESFLVTGSQDCTVK 447
Query: 377 LWDLAAG-----------------KTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKL 505
LW L +TT+R H KD+ SVA + +++ + +GS+D+T KL
Sbjct: 448 LWPLPKALLSKNTAPDNGPILLQAQTTQRC--HDKDINSVAIAPNDKLLATGSQDRTAKL 505
Query: 506 WNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGH 685
W L +C+ GH + CV+FSP + ++ + D T+K+W L + GH
Sbjct: 506 W-ALPQCQLLGVFSGHRRGLWCVQFSP--MDQVLATASADGTIKLWALQDFSCLKTFEGH 562
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGK 787
+ V G+ S G D LW + + +
Sbjct: 563 DASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNE 596
Score = 58.8 bits (136), Expect = 2e-08
Identities = 38/152 (25%), Positives = 64/152 (42%), Gaps = 1/152 (0%)
Frame = +2
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFED-HTKDVLSVAFSVDNRQIVSGSRDKTI 499
LS D ++ S L W G TR ++ HT V ++AF + + +G D +
Sbjct: 74 LSPDNEVLVTASRALLLAQWAWQEGSVTRLWKAIHTAPVATMAFDPTSTLLATGGCDGAV 133
Query: 500 KLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
++W+ + T G V V F P+ ++ S D ++VW L +
Sbjct: 134 RVWDIVRHYG-THHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWSLQDRSCLAVLT 192
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
H + ++ S DG S G+D ++WDL
Sbjct: 193 AHYSAVTSLAFSADGHTMLSSGRDKICIIWDL 224
Score = 55.2 bits (127), Expect = 3e-07
Identities = 51/183 (27%), Positives = 82/183 (44%), Gaps = 18/183 (9%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDL-AAGKT--TRRFEDHTKDVLSVAFS- 454
L+GH+ + + + G S + D+++R+W + AG+ + HT V +V S
Sbjct: 372 LHGHTDIVLALDVFRKGWLFASCAKDQSVRIWRMNKAGQVMCVAQGSGHTHSVGTVCCSR 431
Query: 455 VDNRQIVSGSRDKTIKLWNTLAEC--KYTIQDDG------------HSDWVSCVRFSPNH 592
+ +V+GS+D T+KLW K T D+G H ++ V +PN
Sbjct: 432 LKESFLVTGSQDCTVKLWPLPKALLSKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPN- 490
Query: 593 ANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ ++ + DRT K+W L C+L GH L V SP + A+ D LW
Sbjct: 491 -DKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLATASADGTIKLWA 549
Query: 773 LND 781
L D
Sbjct: 550 LQD 552
Score = 54.0 bits (124), Expect = 6e-07
Identities = 52/217 (23%), Positives = 88/217 (40%), Gaps = 10/217 (4%)
Frame = +2
Query: 149 GHNGWVTQIATNPKYPDMILSSSRDKTLIVWKL--------TRDENNYGIPQKRLYGHSH 304
GH V + + +++ S+D T+ +W L T +N + Q + H
Sbjct: 419 GHTHSVGTVCCSRLKESFLVTGSQDCTVKLWPLPKALLSKNTAPDNGPILLQAQTTQRCH 478
Query: 305 F--ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVS 478
I+ V ++ + +GS D+T +LW L + F H + + V FS ++ + +
Sbjct: 479 DKDINSVAIAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLAT 538
Query: 479 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 658
S D TIKLW L + +GH V V F ++S G D VK+W + N
Sbjct: 539 ASADGTIKLW-ALQDFSCLKTFEGHDASVLKVAFVSRGTQ--LLSSGSDGLVKLWTIKNN 595
Query: 659 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
+ H + + S +G D +LW
Sbjct: 596 ECVRTLDAHEDKVWGLHCSRLDDHALTGASDSRVILW 632
Score = 53.2 bits (122), Expect = 1e-06
Identities = 54/220 (24%), Positives = 95/220 (43%), Gaps = 8/220 (3%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIP-----QKRLYGHSHF 307
L H VT +A + M LSS RDK I+W L + +P + +
Sbjct: 191 LTAHYSAVTSLAFSADGHTM-LSSGRDKICIIWDLQSCQATRTVPVFESVEAAVLLPEEP 249
Query: 308 ISDVVLSSDGNYALSGSWDKTLRLWDLAAGK---TTRRFEDHTKDVLSVAFSVDNRQIVS 478
+S + + S G Y L+ TLR+W+ A+G+ T + +++ + +++
Sbjct: 250 VSQLGVKSPGLYFLTAGDQGTLRVWEAASGQCVYTQAQPPGPGQELTHCTLAHTAGVVLT 309
Query: 479 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 658
+ D + L+ + Q G+S+ V VRF + ++V+ +KV+ L
Sbjct: 310 ATADHNLLLYEA-RSLRLQKQFAGYSEEVLDVRFLGPEDSHVVVASN-SPCLKVFELQTS 367
Query: 659 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLN 778
+I H GH+ + + V G L AS KD +W +N
Sbjct: 368 ACQILH-GHTDIVLALDVFRKGWLFASCAKDQSVRIWRMN 406
Score = 41.5 bits (93), Expect = 0.003
Identities = 30/134 (22%), Positives = 56/134 (41%)
Frame = +2
Query: 128 KLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHF 307
+L G GH + + +P ++ ++S D T+ +W L ++ K GH
Sbjct: 512 QLLGVFSGHRRGLWCVQFSPM-DQVLATASADGTIKLWAL----QDFSC-LKTFEGHDAS 565
Query: 308 ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSR 487
+ V S G LS D ++LW + + R + H V + S + ++G+
Sbjct: 566 VLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAHEDKVWGLHCSRLDDHALTGAS 625
Query: 488 DKTIKLWNTLAECK 529
D + LW + E +
Sbjct: 626 DSRVILWKDVTEAE 639
Score = 40.7 bits (91), Expect = 0.006
Identities = 28/89 (31%), Positives = 45/89 (50%), Gaps = 1/89 (1%)
Frame = +2
Query: 146 RGHNGWVTQIATNPKYPDMIL-SSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
RG G V +A +P ++L SS+ D + VW L +D + + L H ++ +
Sbjct: 148 RGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWSL-QDRSCLAV----LTAHYSAVTSLA 202
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTR 409
S+DG+ LS DK +WDL + + TR
Sbjct: 203 FSADGHTMLSSGRDKICIIWDLQSCQATR 231
Score = 37.9 bits (84), Expect = 0.042
Identities = 28/124 (22%), Positives = 53/124 (42%), Gaps = 2/124 (1%)
Frame = +2
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H+ ++ + +G D +R+WD+ T F V VAF D +++
Sbjct: 108 HTAPVATMAFDPTSTLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLL 167
Query: 476 --SGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 649
S + D I++W +L + H V+ + FS + ++S G D+ +W L
Sbjct: 168 LFSSATDAAIRVW-SLQDRSCLAVLTAHYSAVTSLAFSAD--GHTMLSSGRDKICIIWDL 224
Query: 650 TNCK 661
+C+
Sbjct: 225 QSCQ 228
>BC008991-1|AAH08991.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 340
Score = 77.0 bits (181), Expect = 7e-14
Identities = 57/209 (27%), Positives = 93/209 (44%), Gaps = 3/209 (1%)
Frame = +2
Query: 155 NGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSD 334
+ WV A P + + D ++ L E N + + L GH+ ++S D
Sbjct: 97 SSWVMTCAYAPS-GNYVACGGLDNICSIYNLKTREGNVRV-SRELAGHTGYLSCCRFLDD 154
Query: 335 GNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNT 514
N ++ S D T LWD+ G+ T F HT DV+S++ + D R VSG+ D + KLW+
Sbjct: 155 -NQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDV 213
Query: 515 L-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK--LKINHLGH 685
C+ T GH ++ + F PN N D T +++ L + + +H
Sbjct: 214 REGMCRQTF--TGHESDINAICFFPN-GNAFATGSD-DATCRLFDLRADQELMTYSHDNI 269
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ +V+ S G L +G D +WD
Sbjct: 270 ICGITSVSFSKSGRLLLAGYDDFNCNVWD 298
Score = 74.9 bits (176), Expect = 3e-13
Identities = 57/227 (25%), Positives = 99/227 (43%), Gaps = 4/227 (1%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSH 304
++ R TLRGH + + +++S+S+D LI+W + IP + S
Sbjct: 45 MRTRRTLRGHLAKIYAMHWGTD-SRLLVSASQDGKLIIWDSYTTNKVHAIPLR-----SS 98
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAG----KTTRRFEDHTKDVLSVAFSVDNRQI 472
++ + GNY G D +++L + +R HT LS +D+ QI
Sbjct: 99 WVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHT-GYLSCCRFLDDNQI 157
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
V+ S D T LW+ + + T GH+ V + +P+ + VS D + K+W +
Sbjct: 158 VTSSGDTTCALWD-IETGQQTTTFTGHTGDVMSLSLAPD--TRLFVSGACDASAKLWDVR 214
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ GH +N + P+G+ A+G D L+DL + L
Sbjct: 215 EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQEL 261
Score = 64.9 bits (151), Expect = 3e-10
Identities = 49/212 (23%), Positives = 91/212 (42%), Gaps = 2/212 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH G+++ + I++SS D T +W + + GH+ + +
Sbjct: 139 LAGHTGYLS--CCRFLDDNQIVTSSGDTTCALWDIETGQQT-----TTFTGHTGDVMSLS 191
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
L+ D +SG+ D + +LWD+ G + F H D+ ++ F + +GS D T +
Sbjct: 192 LAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCR 251
Query: 503 LWNTLAECKY-TIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR-TVKVWHLTNCKLKINH 676
L++ A+ + T D ++ V FS + ++ G+D VW
Sbjct: 252 LFDLRADQELMTYSHDNIICGITSVSFSKSGR---LLLAGYDDFNCNVWDALKADRAGVL 308
Query: 677 LGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
GH ++ + V+ DG A+G D +W+
Sbjct: 309 AGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>BC008082-1|AAH08082.1| 423|Homo sapiens WD repeat domain 12
protein.
Length = 423
Score = 77.0 bits (181), Expect = 7e-14
Identities = 52/162 (32%), Positives = 80/162 (49%), Gaps = 3/162 (1%)
Frame = +2
Query: 275 PQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFS 454
P L GH +S V L SD S SWD T+R+WD+ +G + K +++S
Sbjct: 249 PIVTLSGHMEAVSSV-LWSDAEEICSASWDHTIRVWDVESGSLKSTLTGN-KVFNCISYS 306
Query: 455 VDNRQIVSGSRDKTIKLWN--TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR 628
+++ SGS D+ I+LW+ T ++ H+ WV+ V++SP H +I S D
Sbjct: 307 PLCKRLASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLI-SGSLDN 365
Query: 629 TVKVWHLTNCKLKINHL-GHSGYLNTVTVSPDGSLCASGGKD 751
VK+W +CK + L H + +V + D L SGG D
Sbjct: 366 IVKLWDTRSCKAPLYDLAAHEDKVLSVDWT-DTGLLLSGGAD 406
Score = 67.7 bits (158), Expect = 5e-11
Identities = 64/232 (27%), Positives = 97/232 (41%), Gaps = 9/232 (3%)
Frame = +2
Query: 104 FSKMSETLKLRG----TLRGHNGWVTQIATNPK--YPDMILSSSRDKTLIVWKLTRDENN 265
+ K S L G T+ GH V +A K ++LS+S D+T+++W+ + N
Sbjct: 119 YDKTSRIWSLEGKSIMTIVGHTDVVKDVAWVKKDSLSCLLLSASMDQTILLWEWNVERNK 178
Query: 266 YGIPQKRLY---GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDV 436
K L+ GH+ + + + G SGSWDK L++W E+ T
Sbjct: 179 V----KALHCCRGHAGSVDSIAVDGSGTKFCSGSWDKMLKIWSTVPTDEEDEMEEST--- 231
Query: 437 LSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSC 616
NR + KT +L T + GH + VS V +S I S
Sbjct: 232 --------NR---PRKKQKTEQLGLTRTP---IVTLSGHMEAVSSVLWSDAEE---ICSA 274
Query: 617 GWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
WD T++VW + + LK G+ + N ++ SP ASG D LWD
Sbjct: 275 SWDHTIRVWDVESGSLKSTLTGNKVF-NCISYSPLCKRLASGSTDRHIRLWD 325
Score = 48.0 bits (109), Expect = 4e-05
Identities = 30/105 (28%), Positives = 56/105 (53%), Gaps = 5/105 (4%)
Frame = +2
Query: 470 IVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRF-SPNHANPIIVSCGWDRTVKVW- 643
I++GS DKT ++W+ + TI GH+D V V + + + +++S D+T+ +W
Sbjct: 114 ILTGSYDKTSRIWSLEGKSIMTIV--GHTDVVKDVAWVKKDSLSCLLLSASMDQTILLWE 171
Query: 644 -HLTNCKLKINHL--GHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
++ K+K H GH+G ++++ V G+ SG D +W
Sbjct: 172 WNVERNKVKALHCCRGHAGSVDSIAVDGSGTKFCSGSWDKMLKIW 216
Score = 46.8 bits (106), Expect = 9e-05
Identities = 36/129 (27%), Positives = 57/129 (44%), Gaps = 7/129 (5%)
Frame = +2
Query: 152 HNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSS 331
H+ W++ I ++ IL+ S DKT +W L G + GH+ + DV
Sbjct: 100 HDDWISSIKGAEEW---ILTGSYDKTSRIWSLE------GKSIMTIVGHTDVVKDVAWVK 150
Query: 332 DGNYA---LSGSWDKTLRLWDLAAG----KTTRRFEDHTKDVLSVAFSVDNRQIVSGSRD 490
+ + LS S D+T+ LW+ K H V S+A + SGS D
Sbjct: 151 KDSLSCLLLSASMDQTILLWEWNVERNKVKALHCCRGHAGSVDSIAVDGSGTKFCSGSWD 210
Query: 491 KTIKLWNTL 517
K +K+W+T+
Sbjct: 211 KMLKIWSTV 219
Score = 35.9 bits (79), Expect = 0.17
Identities = 27/98 (27%), Positives = 41/98 (41%)
Frame = +2
Query: 80 RESSLFKPFSKMSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDE 259
R L+ P +K + L +L H GWVT + +P + ++S S D + +W D
Sbjct: 319 RHIRLWDPRTKDGSLVSL--SLTSHTGWVTSVKWSPTHEQQLISGSLDNIVKLW----DT 372
Query: 260 NNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTL 373
+ P L H + V + G LSG D L
Sbjct: 373 RSCKAPLYDLAAHEDKVLSVDWTDTG-LLLSGGADNKL 409
>BC007620-1|AAH07620.1| 570|Homo sapiens TBL3 protein protein.
Length = 570
Score = 77.0 bits (181), Expect = 7e-14
Identities = 55/214 (25%), Positives = 101/214 (47%), Gaps = 18/214 (8%)
Frame = +2
Query: 200 MILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSS-DGNYALSGSWDKTLR 376
+ S ++D+++ +W++ + + Q GH+H + V S ++ ++GS D T++
Sbjct: 152 LFASCAKDQSVRIWRMNKAGQVMCVAQGS--GHTHSVGTVCCSRLKESFLVTGSQDCTVK 209
Query: 377 LWDLAAG-----------------KTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKL 505
LW L +TT+R H KD+ SVA + +++ + +GS+D+T KL
Sbjct: 210 LWPLPKALLSKNTAPDNGPILLQAQTTQRC--HDKDINSVAIAPNDKLLATGSQDRTAKL 267
Query: 506 WNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGH 685
W L +C+ GH + CV+FSP + ++ + D T+K+W L + GH
Sbjct: 268 W-ALPQCQLLGVFSGHRRGLWCVQFSP--MDQVLATASADGTIKLWALQDFSCLKTFEGH 324
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGK 787
+ V G+ S G D LW + + +
Sbjct: 325 DASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNE 358
Score = 55.2 bits (127), Expect = 3e-07
Identities = 51/183 (27%), Positives = 82/183 (44%), Gaps = 18/183 (9%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDL-AAGKT--TRRFEDHTKDVLSVAFS- 454
L+GH+ + + + G S + D+++R+W + AG+ + HT V +V S
Sbjct: 134 LHGHTDIVLALDVFRKGWLFASCAKDQSVRIWRMNKAGQVMCVAQGSGHTHSVGTVCCSR 193
Query: 455 VDNRQIVSGSRDKTIKLWNTLAEC--KYTIQDDG------------HSDWVSCVRFSPNH 592
+ +V+GS+D T+KLW K T D+G H ++ V +PN
Sbjct: 194 LKESFLVTGSQDCTVKLWPLPKALLSKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPN- 252
Query: 593 ANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ ++ + DRT K+W L C+L GH L V SP + A+ D LW
Sbjct: 253 -DKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLATASADGTIKLWA 311
Query: 773 LND 781
L D
Sbjct: 312 LQD 314
Score = 54.0 bits (124), Expect = 6e-07
Identities = 52/217 (23%), Positives = 88/217 (40%), Gaps = 10/217 (4%)
Frame = +2
Query: 149 GHNGWVTQIATNPKYPDMILSSSRDKTLIVWKL--------TRDENNYGIPQKRLYGHSH 304
GH V + + +++ S+D T+ +W L T +N + Q + H
Sbjct: 181 GHTHSVGTVCCSRLKESFLVTGSQDCTVKLWPLPKALLSKNTAPDNGPILLQAQTTQRCH 240
Query: 305 F--ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVS 478
I+ V ++ + +GS D+T +LW L + F H + + V FS ++ + +
Sbjct: 241 DKDINSVAIAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLAT 300
Query: 479 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 658
S D TIKLW L + +GH V V F ++S G D VK+W + N
Sbjct: 301 ASADGTIKLW-ALQDFSCLKTFEGHDASVLKVAFVSRGTQ--LLSSGSDGLVKLWTIKNN 357
Query: 659 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
+ H + + S +G D +LW
Sbjct: 358 ECVRTLDAHEDKVWGLHCSRLDDHALTGASDSRVILW 394
Score = 43.2 bits (97), Expect = 0.001
Identities = 38/160 (23%), Positives = 72/160 (45%), Gaps = 3/160 (1%)
Frame = +2
Query: 308 ISDVVLSSDGNYALSGSWDKTLRLWDLAAGK---TTRRFEDHTKDVLSVAFSVDNRQIVS 478
+S + + S G Y L+ TLR+W+ A+G+ T + +++ + +++
Sbjct: 12 VSQLGVKSPGLYFLTAGDQGTLRVWEAASGQCVYTQAQPPGPGQELTHCTLAHTAGVVLT 71
Query: 479 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 658
+ D + L+ + Q G+S+ V VRF + ++V+ +KV+ L
Sbjct: 72 ATADHNLLLYEA-RSLRLQKQFAGYSEEVLDVRFLGPEDSHVVVASN-SPCLKVFELQTS 129
Query: 659 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLN 778
+I H GH+ + + V G L AS KD +W +N
Sbjct: 130 ACQILH-GHTDIVLALDVFRKGWLFASCAKDQSVRIWRMN 168
Score = 41.5 bits (93), Expect = 0.003
Identities = 30/134 (22%), Positives = 56/134 (41%)
Frame = +2
Query: 128 KLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHF 307
+L G GH + + +P ++ ++S D T+ +W L ++ K GH
Sbjct: 274 QLLGVFSGHRRGLWCVQFSPM-DQVLATASADGTIKLWAL----QDFSC-LKTFEGHDAS 327
Query: 308 ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSR 487
+ V S G LS D ++LW + + R + H V + S + ++G+
Sbjct: 328 VLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAHEDKVWGLHCSRLDDHALTGAS 387
Query: 488 DKTIKLWNTLAECK 529
D + LW + E +
Sbjct: 388 DSRVILWKDVTEAE 401
>BC005888-1|AAH05888.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 340
Score = 77.0 bits (181), Expect = 7e-14
Identities = 57/209 (27%), Positives = 93/209 (44%), Gaps = 3/209 (1%)
Frame = +2
Query: 155 NGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSD 334
+ WV A P + + D ++ L E N + + L GH+ ++S D
Sbjct: 97 SSWVMTCAYAPS-GNYVACGGLDNICSIYNLKTREGNVRV-SRELAGHTGYLSCCRFLDD 154
Query: 335 GNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNT 514
N ++ S D T LWD+ G+ T F HT DV+S++ + D R VSG+ D + KLW+
Sbjct: 155 -NQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDV 213
Query: 515 L-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK--LKINHLGH 685
C+ T GH ++ + F PN N D T +++ L + + +H
Sbjct: 214 REGMCRQTF--TGHESDINAICFFPN-GNAFATGSD-DATCRLFDLRADQELMTYSHDNI 269
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ +V+ S G L +G D +WD
Sbjct: 270 ICGITSVSFSKSGRLLLAGYDDFNCNVWD 298
Score = 74.9 bits (176), Expect = 3e-13
Identities = 57/227 (25%), Positives = 99/227 (43%), Gaps = 4/227 (1%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSH 304
++ R TLRGH + + +++S+S+D LI+W + IP + S
Sbjct: 45 MRTRRTLRGHLAKIYAMHWGTD-SRLLVSASQDGKLIIWDSYTTNKVHAIPLR-----SS 98
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAG----KTTRRFEDHTKDVLSVAFSVDNRQI 472
++ + GNY G D +++L + +R HT LS +D+ QI
Sbjct: 99 WVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHT-GYLSCCRFLDDNQI 157
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
V+ S D T LW+ + + T GH+ V + +P+ + VS D + K+W +
Sbjct: 158 VTSSGDTTCALWD-IETGQQTTTFTGHTGDVMSLSLAPD--TRLFVSGACDASAKLWDVR 214
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ GH +N + P+G+ A+G D L+DL + L
Sbjct: 215 EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQEL 261
Score = 64.9 bits (151), Expect = 3e-10
Identities = 49/212 (23%), Positives = 91/212 (42%), Gaps = 2/212 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH G+++ + I++SS D T +W + + GH+ + +
Sbjct: 139 LAGHTGYLS--CCRFLDDNQIVTSSGDTTCALWDIETGQQT-----TTFTGHTGDVMSLS 191
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
L+ D +SG+ D + +LWD+ G + F H D+ ++ F + +GS D T +
Sbjct: 192 LAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCR 251
Query: 503 LWNTLAECKY-TIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR-TVKVWHLTNCKLKINH 676
L++ A+ + T D ++ V FS + ++ G+D VW
Sbjct: 252 LFDLRADQELMTYSHDNIICGITSVSFSKSGR---LLLAGYDDFNCNVWDALKADRAGVL 308
Query: 677 LGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
GH ++ + V+ DG A+G D +W+
Sbjct: 309 AGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>BC004186-1|AAH04186.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 340
Score = 77.0 bits (181), Expect = 7e-14
Identities = 57/209 (27%), Positives = 93/209 (44%), Gaps = 3/209 (1%)
Frame = +2
Query: 155 NGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSD 334
+ WV A P + + D ++ L E N + + L GH+ ++S D
Sbjct: 97 SSWVMTCAYAPS-GNYVACGGLDNICSIYNLKTREGNVRV-SRELAGHTGYLSCCRFLDD 154
Query: 335 GNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNT 514
N ++ S D T LWD+ G+ T F HT DV+S++ + D R VSG+ D + KLW+
Sbjct: 155 -NQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDV 213
Query: 515 L-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK--LKINHLGH 685
C+ T GH ++ + F PN N D T +++ L + + +H
Sbjct: 214 REGMCRQTF--TGHESDINAICFFPN-GNAFATGSD-DATCRLFDLRADQELMTYSHDNI 269
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ +V+ S G L +G D +WD
Sbjct: 270 ICGITSVSFSKSGRLLLAGYDDFNCNVWD 298
Score = 74.9 bits (176), Expect = 3e-13
Identities = 57/227 (25%), Positives = 99/227 (43%), Gaps = 4/227 (1%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSH 304
++ R TLRGH + + +++S+S+D LI+W + IP + S
Sbjct: 45 MRTRRTLRGHLAKIYAMHWGTD-SRLLVSASQDGKLIIWDSYTTNKVHAIPLR-----SS 98
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAG----KTTRRFEDHTKDVLSVAFSVDNRQI 472
++ + GNY G D +++L + +R HT LS +D+ QI
Sbjct: 99 WVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHT-GYLSCCRFLDDNQI 157
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
V+ S D T LW+ + + T GH+ V + +P+ + VS D + K+W +
Sbjct: 158 VTSSGDTTCALWD-IETGQQTTTFTGHTGDVMSLSLAPD--TRLFVSGACDASAKLWDVR 214
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ GH +N + P+G+ A+G D L+DL + L
Sbjct: 215 EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQEL 261
Score = 64.9 bits (151), Expect = 3e-10
Identities = 49/212 (23%), Positives = 91/212 (42%), Gaps = 2/212 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH G+++ + I++SS D T +W + + GH+ + +
Sbjct: 139 LAGHTGYLS--CCRFLDDNQIVTSSGDTTCALWDIETGQQT-----TTFTGHTGDVMSLS 191
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
L+ D +SG+ D + +LWD+ G + F H D+ ++ F + +GS D T +
Sbjct: 192 LAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCR 251
Query: 503 LWNTLAECKY-TIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR-TVKVWHLTNCKLKINH 676
L++ A+ + T D ++ V FS + ++ G+D VW
Sbjct: 252 LFDLRADQELMTYSHDNIICGITSVSFSKSGR---LLLAGYDDFNCNVWDALKADRAGVL 308
Query: 677 LGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
GH ++ + V+ DG A+G D +W+
Sbjct: 309 AGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>AL356133-3|CAH72641.1| 738|Homo sapiens phospholipase
A2-activating protein protein.
Length = 738
Score = 77.0 bits (181), Expect = 7e-14
Identities = 56/213 (26%), Positives = 98/213 (46%), Gaps = 4/213 (1%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPK---YPD-MILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFI 310
+ GH+ +V+ + P YP +I + D + ++ L +P L GH + +
Sbjct: 4 MSGHSNFVSCVCIIPSSDIYPHGLIATGGNDHNICIFSLDSP-----MPLYILKGHKNTV 58
Query: 311 SDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRD 490
+ G LSGSWD T ++W K + HT V +V + +++GS D
Sbjct: 59 CSLSSGKFGTL-LSGSWDTTAKVW--LNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSAD 115
Query: 491 KTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKI 670
KT+KLW C+ T GH D CVR + +SC D +++ W +T L++
Sbjct: 116 KTVKLWKA-GRCERTF--SGHED---CVRGLAILSETEFLSCANDASIRRWQITGECLEV 169
Query: 671 NHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
+ GH+ Y+ +++V P+ + +D +W
Sbjct: 170 -YYGHTNYIYSISVFPNCRDFVTTAEDRSLRIW 201
>AL109917-5|CAI95654.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 340
Score = 77.0 bits (181), Expect = 7e-14
Identities = 57/209 (27%), Positives = 93/209 (44%), Gaps = 3/209 (1%)
Frame = +2
Query: 155 NGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSD 334
+ WV A P + + D ++ L E N + + L GH+ ++S D
Sbjct: 97 SSWVMTCAYAPS-GNYVACGGLDNICSIYNLKTREGNVRV-SRELAGHTGYLSCCRFLDD 154
Query: 335 GNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNT 514
N ++ S D T LWD+ G+ T F HT DV+S++ + D R VSG+ D + KLW+
Sbjct: 155 -NQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDV 213
Query: 515 L-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK--LKINHLGH 685
C+ T GH ++ + F PN N D T +++ L + + +H
Sbjct: 214 REGMCRQTF--TGHESDINAICFFPN-GNAFATGSD-DATCRLFDLRADQELMTYSHDNI 269
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ +V+ S G L +G D +WD
Sbjct: 270 ICGITSVSFSKSGRLLLAGYDDFNCNVWD 298
Score = 74.9 bits (176), Expect = 3e-13
Identities = 57/227 (25%), Positives = 99/227 (43%), Gaps = 4/227 (1%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSH 304
++ R TLRGH + + +++S+S+D LI+W + IP + S
Sbjct: 45 MRTRRTLRGHLAKIYAMHWGTD-SRLLVSASQDGKLIIWDSYTTNKVHAIPLR-----SS 98
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAG----KTTRRFEDHTKDVLSVAFSVDNRQI 472
++ + GNY G D +++L + +R HT LS +D+ QI
Sbjct: 99 WVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHT-GYLSCCRFLDDNQI 157
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
V+ S D T LW+ + + T GH+ V + +P+ + VS D + K+W +
Sbjct: 158 VTSSGDTTCALWD-IETGQQTTTFTGHTGDVMSLSLAPD--TRLFVSGACDASAKLWDVR 214
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ GH +N + P+G+ A+G D L+DL + L
Sbjct: 215 EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQEL 261
Score = 64.9 bits (151), Expect = 3e-10
Identities = 49/212 (23%), Positives = 91/212 (42%), Gaps = 2/212 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH G+++ + I++SS D T +W + + GH+ + +
Sbjct: 139 LAGHTGYLS--CCRFLDDNQIVTSSGDTTCALWDIETGQQT-----TTFTGHTGDVMSLS 191
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
L+ D +SG+ D + +LWD+ G + F H D+ ++ F + +GS D T +
Sbjct: 192 LAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCR 251
Query: 503 LWNTLAECKY-TIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR-TVKVWHLTNCKLKINH 676
L++ A+ + T D ++ V FS + ++ G+D VW
Sbjct: 252 LFDLRADQELMTYSHDNIICGITSVSFSKSGR---LLLAGYDDFNCNVWDALKADRAGVL 308
Query: 677 LGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
GH ++ + V+ DG A+G D +W+
Sbjct: 309 AGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>AL031282-2|CAI20029.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 340
Score = 77.0 bits (181), Expect = 7e-14
Identities = 57/209 (27%), Positives = 93/209 (44%), Gaps = 3/209 (1%)
Frame = +2
Query: 155 NGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSD 334
+ WV A P + + D ++ L E N + + L GH+ ++S D
Sbjct: 97 SSWVMTCAYAPS-GNYVACGGLDNICSIYNLKTREGNVRV-SRELAGHTGYLSCCRFLDD 154
Query: 335 GNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNT 514
N ++ S D T LWD+ G+ T F HT DV+S++ + D R VSG+ D + KLW+
Sbjct: 155 -NQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDV 213
Query: 515 L-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK--LKINHLGH 685
C+ T GH ++ + F PN N D T +++ L + + +H
Sbjct: 214 REGMCRQTF--TGHESDINAICFFPN-GNAFATGSD-DATCRLFDLRADQELMTYSHDNI 269
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ +V+ S G L +G D +WD
Sbjct: 270 ICGITSVSFSKSGRLLLAGYDDFNCNVWD 298
Score = 74.9 bits (176), Expect = 3e-13
Identities = 57/227 (25%), Positives = 99/227 (43%), Gaps = 4/227 (1%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSH 304
++ R TLRGH + + +++S+S+D LI+W + IP + S
Sbjct: 45 MRTRRTLRGHLAKIYAMHWGTD-SRLLVSASQDGKLIIWDSYTTNKVHAIPLR-----SS 98
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAG----KTTRRFEDHTKDVLSVAFSVDNRQI 472
++ + GNY G D +++L + +R HT LS +D+ QI
Sbjct: 99 WVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHT-GYLSCCRFLDDNQI 157
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
V+ S D T LW+ + + T GH+ V + +P+ + VS D + K+W +
Sbjct: 158 VTSSGDTTCALWD-IETGQQTTTFTGHTGDVMSLSLAPD--TRLFVSGACDASAKLWDVR 214
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ GH +N + P+G+ A+G D L+DL + L
Sbjct: 215 EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQEL 261
Score = 64.9 bits (151), Expect = 3e-10
Identities = 49/212 (23%), Positives = 91/212 (42%), Gaps = 2/212 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH G+++ + I++SS D T +W + + GH+ + +
Sbjct: 139 LAGHTGYLS--CCRFLDDNQIVTSSGDTTCALWDIETGQQT-----TTFTGHTGDVMSLS 191
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
L+ D +SG+ D + +LWD+ G + F H D+ ++ F + +GS D T +
Sbjct: 192 LAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCR 251
Query: 503 LWNTLAECKY-TIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR-TVKVWHLTNCKLKINH 676
L++ A+ + T D ++ V FS + ++ G+D VW
Sbjct: 252 LFDLRADQELMTYSHDNIICGITSVSFSKSGR---LLLAGYDDFNCNVWDALKADRAGVL 308
Query: 677 LGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
GH ++ + V+ DG A+G D +W+
Sbjct: 309 AGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>AK223544-1|BAD97264.1| 748|Homo sapiens Hypothetical protein
DKFZp434J1217 (PLAA protein) (OTTHUMP00000045176)
variant protein.
Length = 748
Score = 77.0 bits (181), Expect = 7e-14
Identities = 56/213 (26%), Positives = 98/213 (46%), Gaps = 4/213 (1%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPK---YPD-MILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFI 310
+ GH+ +V+ + P YP +I + D + ++ L +P L GH + +
Sbjct: 14 MSGHSNFVSCVCIIPSSDIYPHGLIATGGNDHNICIFSLDSP-----MPLYILKGHKNTV 68
Query: 311 SDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRD 490
+ G LSGSWD T ++W K + HT V +V + +++GS D
Sbjct: 69 CSLSSGKFGTL-LSGSWDTTAKVW--LNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSAD 125
Query: 491 KTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKI 670
KT+KLW C+ T GH D CVR + +SC D +++ W +T L++
Sbjct: 126 KTVKLWKA-GRCERTF--SGHED---CVRGLAILSETEFLSCANDASIRRWQITGECLEV 179
Query: 671 NHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
+ GH+ Y+ +++V P+ + +D +W
Sbjct: 180 -YYGHTNYIYSISVFPNCRDFVTTAEDRSLRIW 211
>AK074917-1|BAC11291.1| 421|Homo sapiens protein ( Homo sapiens
cDNA FLJ90436 fis, clone NT2RP3000820, weakly similar to
PUTATIVE SERINE/THREONINE-PROTEIN KINASE PKWA (EC
2.7.1.-). ).
Length = 421
Score = 77.0 bits (181), Expect = 7e-14
Identities = 42/139 (30%), Positives = 70/139 (50%), Gaps = 1/139 (0%)
Frame = +2
Query: 371 LRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI-VSGSRDKTIKLWNTLAECKYTIQDD 547
+++WD+ GK DHT+ V + F+ D I VS SRDKT+++W+ +
Sbjct: 152 IKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKVLR 211
Query: 548 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 727
GH +WV FSP+ + ++ S G + V +W++ + GH + SPDG+
Sbjct: 212 GHQNWVYSCAFSPDSS--MLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVACDFSPDGA 269
Query: 728 LCASGGKDMXAMLWDLNDG 784
L A+ D +WD ++G
Sbjct: 270 LLATASYDTRVYIWDPHNG 288
Score = 67.7 bits (158), Expect = 5e-11
Identities = 64/229 (27%), Positives = 99/229 (43%), Gaps = 13/229 (5%)
Frame = +2
Query: 122 TLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHS 301
T KL L H V + P +++S+SRDKTL VW L +D+ N K L GH
Sbjct: 159 TGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDL-KDDGNM---MKVLRGHQ 214
Query: 302 HFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSG 481
+++ S D + S K + LW++ R+ E H DV++ FS D + +
Sbjct: 215 NWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVACDFSPDGALLATA 274
Query: 482 SRDKTIKLW-----NTLAECKY------TIQDDGHSD-WVSCVRFSPNHANPIIVSCGWD 625
S D + +W + L E + I G +D WV V FS H + S D
Sbjct: 275 SYDTRVYIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSFS--HDGLHVASLADD 332
Query: 626 RTVKVWHL-TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
+ V+ W + + +++ L + S DGS+ A+G D W
Sbjct: 333 KMVRFWRIDEDYPVQVAPLSNG---LCCAFSTDGSVLAAGTHDGSVYFW 378
>AK001743-1|BAA91875.1| 423|Homo sapiens protein ( Homo sapiens
cDNA FLJ10881 fis, clone NT2RP4001927, weakly similar to
MICROTUBULE-ASSOCIATED PROTEIN YTM1. ).
Length = 423
Score = 77.0 bits (181), Expect = 7e-14
Identities = 52/162 (32%), Positives = 80/162 (49%), Gaps = 3/162 (1%)
Frame = +2
Query: 275 PQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFS 454
P L GH +S V L SD S SWD T+R+WD+ +G + K +++S
Sbjct: 249 PIVTLSGHMEAVSSV-LWSDAEEICSASWDHTIRVWDVESGSLKSTLTGN-KVFNCISYS 306
Query: 455 VDNRQIVSGSRDKTIKLWN--TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR 628
+++ SGS D+ I+LW+ T ++ H+ WV+ V++SP H +I S D
Sbjct: 307 PLCKRLASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLI-SGSLDN 365
Query: 629 TVKVWHLTNCKLKINHL-GHSGYLNTVTVSPDGSLCASGGKD 751
VK+W +CK + L H + +V + D L SGG D
Sbjct: 366 IVKLWDTRSCKAPLYDLAAHEDKVLSVDWT-DTGLLLSGGAD 406
Score = 67.7 bits (158), Expect = 5e-11
Identities = 64/232 (27%), Positives = 97/232 (41%), Gaps = 9/232 (3%)
Frame = +2
Query: 104 FSKMSETLKLRG----TLRGHNGWVTQIATNPK--YPDMILSSSRDKTLIVWKLTRDENN 265
+ K S L G T+ GH V +A K ++LS+S D+T+++W+ + N
Sbjct: 119 YDKTSRIWSLEGKSIMTIVGHTDVVKDVAWVKKDSLSCLLLSASMDQTILLWEWNVERNK 178
Query: 266 YGIPQKRLY---GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDV 436
K L+ GH+ + + + G SGSWDK L++W E+ T
Sbjct: 179 V----KALHCCRGHAGSVDSIAVDGSGTKFCSGSWDKMLKIWSTVPTDEEDEMEEST--- 231
Query: 437 LSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSC 616
NR + KT +L T + GH + VS V +S I S
Sbjct: 232 --------NR---PRKKQKTEQLGLTRTP---IVTLSGHMEAVSSVLWSDAEE---ICSA 274
Query: 617 GWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
WD T++VW + + LK G+ + N ++ SP ASG D LWD
Sbjct: 275 SWDHTIRVWDVESGSLKSTLTGNKVF-NCISYSPLCKRLASGSTDRHIRLWD 325
Score = 48.0 bits (109), Expect = 4e-05
Identities = 30/105 (28%), Positives = 56/105 (53%), Gaps = 5/105 (4%)
Frame = +2
Query: 470 IVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRF-SPNHANPIIVSCGWDRTVKVW- 643
I++GS DKT ++W+ + TI GH+D V V + + + +++S D+T+ +W
Sbjct: 114 ILTGSYDKTSRIWSLEGKSIMTIV--GHTDVVKDVAWVKKDSLSCLLLSASMDQTILLWE 171
Query: 644 -HLTNCKLKINHL--GHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
++ K+K H GH+G ++++ V G+ SG D +W
Sbjct: 172 WNVERNKVKALHCCRGHAGSVDSIAVDGSGTKFCSGSWDKMLKIW 216
Score = 46.8 bits (106), Expect = 9e-05
Identities = 36/129 (27%), Positives = 57/129 (44%), Gaps = 7/129 (5%)
Frame = +2
Query: 152 HNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSS 331
H+ W++ I ++ IL+ S DKT +W L G + GH+ + DV
Sbjct: 100 HDDWISSIKGAEEW---ILTGSYDKTSRIWSLE------GKSIMTIVGHTDVVKDVAWVK 150
Query: 332 DGNYA---LSGSWDKTLRLWDLAAG----KTTRRFEDHTKDVLSVAFSVDNRQIVSGSRD 490
+ + LS S D+T+ LW+ K H V S+A + SGS D
Sbjct: 151 KDSLSCLLLSASMDQTILLWEWNVERNKVKALHCCRGHAGSVDSIAVDGSGTKFCSGSWD 210
Query: 491 KTIKLWNTL 517
K +K+W+T+
Sbjct: 211 KMLKIWSTV 219
Score = 35.9 bits (79), Expect = 0.17
Identities = 27/98 (27%), Positives = 41/98 (41%)
Frame = +2
Query: 80 RESSLFKPFSKMSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDE 259
R L+ P +K + L +L H GWVT + +P + ++S S D + +W D
Sbjct: 319 RHIRLWDPRTKDGSLVSL--SLTSHTGWVTSVKWSPTHEQQLISGSLDNIVKLW----DT 372
Query: 260 NNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTL 373
+ P L H + V + G LSG D L
Sbjct: 373 RSCKAPLYDLAAHEDKVLSVDWTDTG-LLLSGGADNKL 409
>AJ238243-1|CAB42881.1| 738|Homo sapiens phospholipase A2
activating protein protein.
Length = 738
Score = 77.0 bits (181), Expect = 7e-14
Identities = 56/213 (26%), Positives = 98/213 (46%), Gaps = 4/213 (1%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPK---YPD-MILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFI 310
+ GH+ +V+ + P YP +I + D + ++ L +P L GH + +
Sbjct: 4 MSGHSNFVSCVCIIPSSDIYPHGLIATGGNDHNICIFSLDSP-----MPLYILKGHKNTV 58
Query: 311 SDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRD 490
+ G LSGSWD T ++W K + HT V +V + +++GS D
Sbjct: 59 CSLSSGKFGTL-LSGSWDTTAKVW--LNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSAD 115
Query: 491 KTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKI 670
KT+KLW C+ T GH D CVR + +SC D +++ W +T L++
Sbjct: 116 KTVKLWKA-GRCERTF--SGHED---CVRGLAILSETEFLSCANDASIRRWQITGECLEV 169
Query: 671 NHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
+ GH+ Y+ +++V P+ + +D +W
Sbjct: 170 -YYGHTNYIYSISVFPNCRDFVTTAEDRSLRIW 201
>AF501882-1|AAM15918.1| 340|Homo sapiens guanine nucleotide binding
protein beta 1 protein.
Length = 340
Score = 77.0 bits (181), Expect = 7e-14
Identities = 57/209 (27%), Positives = 93/209 (44%), Gaps = 3/209 (1%)
Frame = +2
Query: 155 NGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSD 334
+ WV A P + + D ++ L E N + + L GH+ ++S D
Sbjct: 97 SSWVMTCAYAPS-GNYVACGGLDNICSIYNLKTREGNVRV-SRELAGHTGYLSCCRFLDD 154
Query: 335 GNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNT 514
N ++ S D T LWD+ G+ T F HT DV+S++ + D R VSG+ D + KLW+
Sbjct: 155 -NQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDV 213
Query: 515 L-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK--LKINHLGH 685
C+ T GH ++ + F PN N D T +++ L + + +H
Sbjct: 214 REGMCRQTF--TGHESDINAICFFPN-GNAFATGSD-DATCRLFDLRADQELMTYSHDNI 269
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ +V+ S G L +G D +WD
Sbjct: 270 ICGITSVSFSKSGRLLLAGYDDFNCNVWD 298
Score = 74.9 bits (176), Expect = 3e-13
Identities = 57/227 (25%), Positives = 99/227 (43%), Gaps = 4/227 (1%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSH 304
++ R TLRGH + + +++S+S+D LI+W + IP + S
Sbjct: 45 MRTRRTLRGHLAKIYAMHWGTD-SRLLVSASQDGKLIIWDSYTTNKVHAIPLR-----SS 98
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAG----KTTRRFEDHTKDVLSVAFSVDNRQI 472
++ + GNY G D +++L + +R HT LS +D+ QI
Sbjct: 99 WVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHT-GYLSCCRFLDDNQI 157
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
V+ S D T LW+ + + T GH+ V + +P+ + VS D + K+W +
Sbjct: 158 VTSSGDTTCALWD-IETGQQTTTFTGHTGDVMSLSLAPD--TRLFVSGACDASAKLWDVR 214
Query: 653 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ GH +N + P+G+ A+G D L+DL + L
Sbjct: 215 EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQEL 261
Score = 64.9 bits (151), Expect = 3e-10
Identities = 49/212 (23%), Positives = 91/212 (42%), Gaps = 2/212 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH G+++ + I++SS D T +W + + GH+ + +
Sbjct: 139 LAGHTGYLS--CCRFLDDNQIVTSSGDTTCALWDIETGQQT-----TTFTGHTGDVMSLS 191
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
L+ D +SG+ D + +LWD+ G + F H D+ ++ F + +GS D T +
Sbjct: 192 LAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCR 251
Query: 503 LWNTLAECKY-TIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR-TVKVWHLTNCKLKINH 676
L++ A+ + T D ++ V FS + ++ G+D VW
Sbjct: 252 LFDLRADQELMTYSHDNIICGITSVSFSKSGR---LLLAGYDDFNCNVWDALKADRAGVL 308
Query: 677 LGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
GH ++ + V+ DG A+G D +W+
Sbjct: 309 AGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>AF112205-1|AAF17193.1| 421|Homo sapiens WSB-1 protein protein.
Length = 421
Score = 77.0 bits (181), Expect = 7e-14
Identities = 42/139 (30%), Positives = 70/139 (50%), Gaps = 1/139 (0%)
Frame = +2
Query: 371 LRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI-VSGSRDKTIKLWNTLAECKYTIQDD 547
+++WD+ GK DHT+ V + F+ D I VS SRDKT+++W+ +
Sbjct: 152 IKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKVLR 211
Query: 548 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 727
GH +WV FSP+ + ++ S G + V +W++ + GH + SPDG+
Sbjct: 212 GHQNWVYSCAFSPDSS--MLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVACDFSPDGA 269
Query: 728 LCASGGKDMXAMLWDLNDG 784
L A+ D +WD ++G
Sbjct: 270 LLATASYDTRVYIWDPHNG 288
Score = 67.7 bits (158), Expect = 5e-11
Identities = 64/229 (27%), Positives = 99/229 (43%), Gaps = 13/229 (5%)
Frame = +2
Query: 122 TLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHS 301
T KL L H V + P +++S+SRDKTL VW L +D+ N K L GH
Sbjct: 159 TGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDL-KDDGNM---MKVLRGHQ 214
Query: 302 HFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSG 481
+++ S D + S K + LW++ R+ E H DV++ FS D + +
Sbjct: 215 NWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVACDFSPDGALLATA 274
Query: 482 SRDKTIKLW-----NTLAECKY------TIQDDGHSD-WVSCVRFSPNHANPIIVSCGWD 625
S D + +W + L E + I G +D WV V FS H + S D
Sbjct: 275 SYDTRVYIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSFS--HDGLHVASLADD 332
Query: 626 RTVKVWHL-TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
+ V+ W + + +++ L + S DGS+ A+G D W
Sbjct: 333 KMVRFWRIDEDYPVQVAPLSNG---LCCAFSTDGSVLAAGTHDGSVYFW 378
>AF083395-1|AAD03030.1| 738|Homo sapiens phospholipase
A2-activating protein protein.
Length = 738
Score = 77.0 bits (181), Expect = 7e-14
Identities = 56/213 (26%), Positives = 98/213 (46%), Gaps = 4/213 (1%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPK---YPD-MILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFI 310
+ GH+ +V+ + P YP +I + D + ++ L +P L GH + +
Sbjct: 4 MSGHSNFVSCVCIIPSSDIYPHGLIATGGNDHNICIFSLDSP-----MPLYILKGHKNTV 58
Query: 311 SDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRD 490
+ G LSGSWD T ++W K + HT V +V + +++GS D
Sbjct: 59 CSLSSGKFGTL-LSGSWDTTAKVW--LNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSAD 115
Query: 491 KTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKI 670
KT+KLW C+ T GH D CVR + +SC D +++ W +T L++
Sbjct: 116 KTVKLWKA-GRCERTF--SGHED---CVRGLAILSETEFLSCANDASIRRWQITGECLEV 169
Query: 671 NHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
+ GH+ Y+ +++V P+ + +D +W
Sbjct: 170 -YYGHTNYIYSISVFPNCRDFVTTAEDRSLRIW 201
>AF072880-1|AAD28808.1| 421|Homo sapiens SOCS box-containing WD
protein SWiP-1 protein.
Length = 421
Score = 77.0 bits (181), Expect = 7e-14
Identities = 42/139 (30%), Positives = 70/139 (50%), Gaps = 1/139 (0%)
Frame = +2
Query: 371 LRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI-VSGSRDKTIKLWNTLAECKYTIQDD 547
+++WD+ GK DHT+ V + F+ D I VS SRDKT+++W+ +
Sbjct: 152 IKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKVLR 211
Query: 548 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 727
GH +WV FSP+ + ++ S G + V +W++ + GH + SPDG+
Sbjct: 212 GHQNWVYSCAFSPDSS--MLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVACDFSPDGA 269
Query: 728 LCASGGKDMXAMLWDLNDG 784
L A+ D +WD ++G
Sbjct: 270 LLATASYDTRVYIWDPHNG 288
Score = 67.7 bits (158), Expect = 5e-11
Identities = 64/229 (27%), Positives = 99/229 (43%), Gaps = 13/229 (5%)
Frame = +2
Query: 122 TLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHS 301
T KL L H V + P +++S+SRDKTL VW L +D+ N K L GH
Sbjct: 159 TGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDL-KDDGNM---MKVLRGHQ 214
Query: 302 HFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSG 481
+++ S D + S K + LW++ R+ E H DV++ FS D + +
Sbjct: 215 NWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVACDFSPDGALLATA 274
Query: 482 SRDKTIKLW-----NTLAECKY------TIQDDGHSD-WVSCVRFSPNHANPIIVSCGWD 625
S D + +W + L E + I G +D WV V FS H + S D
Sbjct: 275 SYDTRVYIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSFS--HDGLHVASLADD 332
Query: 626 RTVKVWHL-TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
+ V+ W + + +++ L + S DGS+ A+G D W
Sbjct: 333 KMVRFWRIDEDYPVQVAPLSNG---LCCAFSTDGSVLAAGTHDGSVYFW 378
>AF069313-1|AAD20954.2| 421|Homo sapiens WSB1 protein protein.
Length = 421
Score = 77.0 bits (181), Expect = 7e-14
Identities = 42/139 (30%), Positives = 70/139 (50%), Gaps = 1/139 (0%)
Frame = +2
Query: 371 LRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI-VSGSRDKTIKLWNTLAECKYTIQDD 547
+++WD+ GK DHT+ V + F+ D I VS SRDKT+++W+ +
Sbjct: 152 IKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKVLR 211
Query: 548 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 727
GH +WV FSP+ + ++ S G + V +W++ + GH + SPDG+
Sbjct: 212 GHQNWVYSCAFSPDSS--MLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVACDFSPDGA 269
Query: 728 LCASGGKDMXAMLWDLNDG 784
L A+ D +WD ++G
Sbjct: 270 LLATASYDTRVYIWDPHNG 288
Score = 67.7 bits (158), Expect = 5e-11
Identities = 64/229 (27%), Positives = 99/229 (43%), Gaps = 13/229 (5%)
Frame = +2
Query: 122 TLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHS 301
T KL L H V + P +++S+SRDKTL VW L +D+ N K L GH
Sbjct: 159 TGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDL-KDDGNM---MKVLRGHQ 214
Query: 302 HFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSG 481
+++ S D + S K + LW++ R+ E H DV++ FS D + +
Sbjct: 215 NWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVACDFSPDGALLATA 274
Query: 482 SRDKTIKLW-----NTLAECKY------TIQDDGHSD-WVSCVRFSPNHANPIIVSCGWD 625
S D + +W + L E + I G +D WV V FS H + S D
Sbjct: 275 SYDTRVYIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSFS--HDGLHVASLADD 332
Query: 626 RTVKVWHL-TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
+ V+ W + + +++ L + S DGS+ A+G D W
Sbjct: 333 KMVRFWRIDEDYPVQVAPLSNG---LCCAFSTDGSVLAAGTHDGSVYFW 378
>AC010900-2|AAY24287.1| 423|Homo sapiens unknown protein.
Length = 423
Score = 77.0 bits (181), Expect = 7e-14
Identities = 52/162 (32%), Positives = 80/162 (49%), Gaps = 3/162 (1%)
Frame = +2
Query: 275 PQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFS 454
P L GH +S V L SD S SWD T+R+WD+ +G + K +++S
Sbjct: 249 PIVTLSGHMEAVSSV-LWSDAEEICSASWDHTIRVWDVESGSLKSTLTGN-KVFNCISYS 306
Query: 455 VDNRQIVSGSRDKTIKLWN--TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR 628
+++ SGS D+ I+LW+ T ++ H+ WV+ V++SP H +I S D
Sbjct: 307 PLCKRLASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLI-SGSLDN 365
Query: 629 TVKVWHLTNCKLKINHL-GHSGYLNTVTVSPDGSLCASGGKD 751
VK+W +CK + L H + +V + D L SGG D
Sbjct: 366 IVKLWDTRSCKAPLYDLAAHEDKVLSVDWT-DTGLLLSGGAD 406
Score = 67.7 bits (158), Expect = 5e-11
Identities = 64/232 (27%), Positives = 97/232 (41%), Gaps = 9/232 (3%)
Frame = +2
Query: 104 FSKMSETLKLRG----TLRGHNGWVTQIATNPK--YPDMILSSSRDKTLIVWKLTRDENN 265
+ K S L G T+ GH V +A K ++LS+S D+T+++W+ + N
Sbjct: 119 YDKTSRIWSLEGKSIMTIVGHTDVVKDVAWVKKDSLSCLLLSASMDQTILLWEWNVERNK 178
Query: 266 YGIPQKRLY---GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDV 436
K L+ GH+ + + + G SGSWDK L++W E+ T
Sbjct: 179 V----KALHCCRGHAGSVDSIAVDGSGTKFCSGSWDKMLKIWSTVPTDEEDEMEEST--- 231
Query: 437 LSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSC 616
NR + KT +L T + GH + VS V +S I S
Sbjct: 232 --------NR---PRKKQKTEQLGLTRTP---IVTLSGHMEAVSSVLWSDAEE---ICSA 274
Query: 617 GWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
WD T++VW + + LK G+ + N ++ SP ASG D LWD
Sbjct: 275 SWDHTIRVWDVESGSLKSTLTGNKVF-NCISYSPLCKRLASGSTDRHIRLWD 325
Score = 48.0 bits (109), Expect = 4e-05
Identities = 30/105 (28%), Positives = 56/105 (53%), Gaps = 5/105 (4%)
Frame = +2
Query: 470 IVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRF-SPNHANPIIVSCGWDRTVKVW- 643
I++GS DKT ++W+ + TI GH+D V V + + + +++S D+T+ +W
Sbjct: 114 ILTGSYDKTSRIWSLEGKSIMTIV--GHTDVVKDVAWVKKDSLSCLLLSASMDQTILLWE 171
Query: 644 -HLTNCKLKINHL--GHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
++ K+K H GH+G ++++ V G+ SG D +W
Sbjct: 172 WNVERNKVKALHCCRGHAGSVDSIAVDGSGTKFCSGSWDKMLKIW 216
Score = 46.8 bits (106), Expect = 9e-05
Identities = 36/129 (27%), Positives = 57/129 (44%), Gaps = 7/129 (5%)
Frame = +2
Query: 152 HNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSS 331
H+ W++ I ++ IL+ S DKT +W L G + GH+ + DV
Sbjct: 100 HDDWISSIKGAEEW---ILTGSYDKTSRIWSLE------GKSIMTIVGHTDVVKDVAWVK 150
Query: 332 DGNYA---LSGSWDKTLRLWDLAAG----KTTRRFEDHTKDVLSVAFSVDNRQIVSGSRD 490
+ + LS S D+T+ LW+ K H V S+A + SGS D
Sbjct: 151 KDSLSCLLLSASMDQTILLWEWNVERNKVKALHCCRGHAGSVDSIAVDGSGTKFCSGSWD 210
Query: 491 KTIKLWNTL 517
K +K+W+T+
Sbjct: 211 KMLKIWSTV 219
Score = 35.9 bits (79), Expect = 0.17
Identities = 27/98 (27%), Positives = 41/98 (41%)
Frame = +2
Query: 80 RESSLFKPFSKMSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDE 259
R L+ P +K + L +L H GWVT + +P + ++S S D + +W D
Sbjct: 319 RHIRLWDPRTKDGSLVSL--SLTSHTGWVTSVKWSPTHEQQLISGSLDNIVKLW----DT 372
Query: 260 NNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTL 373
+ P L H + V + G LSG D L
Sbjct: 373 RSCKAPLYDLAAHEDKVLSVDWTDTG-LLLSGGADNKL 409
>AB209173-1|BAD92410.1| 832|Homo sapiens transducin beta-like 3
variant protein.
Length = 832
Score = 77.0 bits (181), Expect = 7e-14
Identities = 55/214 (25%), Positives = 101/214 (47%), Gaps = 18/214 (8%)
Frame = +2
Query: 200 MILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSS-DGNYALSGSWDKTLR 376
+ S ++D+++ +W++ + + Q GH+H + V S ++ ++GS D T++
Sbjct: 414 LFASCAKDQSVRIWRMNKAGQVMCVAQGS--GHTHSVGTVCCSRLKESFLVTGSQDCTVK 471
Query: 377 LWDLAAG-----------------KTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKL 505
LW L +TT+R H KD+ SVA + +++ + +GS+D+T KL
Sbjct: 472 LWPLPKALLPKNTAPDNGPILLQAQTTQRC--HDKDINSVAIAPNDKLLATGSQDRTAKL 529
Query: 506 WNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGH 685
W L +C+ GH + CV+FSP + ++ + D T+K+W L + GH
Sbjct: 530 W-ALPQCQLLGVFSGHRRGLWCVQFSP--MDQVLATASADGTIKLWALQDFSCLKTFEGH 586
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGK 787
+ V G+ S G D LW + + +
Sbjct: 587 DASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNE 620
Score = 58.8 bits (136), Expect = 2e-08
Identities = 38/152 (25%), Positives = 64/152 (42%), Gaps = 1/152 (0%)
Frame = +2
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFED-HTKDVLSVAFSVDNRQIVSGSRDKTI 499
LS D ++ S L W G TR ++ HT V ++AF + + +G D +
Sbjct: 98 LSPDNEVLVTASRALLLAQWAWQEGSVTRLWKAIHTAPVATMAFDPTSTLLATGGCDGAV 157
Query: 500 KLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 679
++W+ + T G V V F P+ ++ S D ++VW L +
Sbjct: 158 RVWDIVRHYG-THHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWSLQDRSCLAVLT 216
Query: 680 GHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
H + ++ S DG S G+D ++WDL
Sbjct: 217 AHYSAVTSLAFSADGHTMLSSGRDKICIIWDL 248
Score = 55.2 bits (127), Expect = 3e-07
Identities = 51/183 (27%), Positives = 82/183 (44%), Gaps = 18/183 (9%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDL-AAGKT--TRRFEDHTKDVLSVAFS- 454
L+GH+ + + + G S + D+++R+W + AG+ + HT V +V S
Sbjct: 396 LHGHTDIVLALDVFRKGWLFASCAKDQSVRIWRMNKAGQVMCVAQGSGHTHSVGTVCCSR 455
Query: 455 VDNRQIVSGSRDKTIKLWNTLAEC--KYTIQDDG------------HSDWVSCVRFSPNH 592
+ +V+GS+D T+KLW K T D+G H ++ V +PN
Sbjct: 456 LKESFLVTGSQDCTVKLWPLPKALLPKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPN- 514
Query: 593 ANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ ++ + DRT K+W L C+L GH L V SP + A+ D LW
Sbjct: 515 -DKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLATASADGTIKLWA 573
Query: 773 LND 781
L D
Sbjct: 574 LQD 576
Score = 54.0 bits (124), Expect = 6e-07
Identities = 52/217 (23%), Positives = 88/217 (40%), Gaps = 10/217 (4%)
Frame = +2
Query: 149 GHNGWVTQIATNPKYPDMILSSSRDKTLIVWKL--------TRDENNYGIPQKRLYGHSH 304
GH V + + +++ S+D T+ +W L T +N + Q + H
Sbjct: 443 GHTHSVGTVCCSRLKESFLVTGSQDCTVKLWPLPKALLPKNTAPDNGPILLQAQTTQRCH 502
Query: 305 F--ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVS 478
I+ V ++ + +GS D+T +LW L + F H + + V FS ++ + +
Sbjct: 503 DKDINSVAIAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLAT 562
Query: 479 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 658
S D TIKLW L + +GH V V F ++S G D VK+W + N
Sbjct: 563 ASADGTIKLW-ALQDFSCLKTFEGHDASVLKVAFVSRGTQ--LLSSGSDGLVKLWTIKNN 619
Query: 659 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
+ H + + S +G D +LW
Sbjct: 620 ECVRTLDAHEDKVWGLHCSRLDDHALTGASDSRVILW 656
Score = 53.6 bits (123), Expect = 8e-07
Identities = 54/220 (24%), Positives = 95/220 (43%), Gaps = 8/220 (3%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIP-----QKRLYGHSHF 307
L H VT +A + M LSS RDK I+W L + +P + +
Sbjct: 215 LTAHYSAVTSLAFSADGHTM-LSSGRDKICIIWDLQSCQATRTVPVFESVEAAVLLPEEP 273
Query: 308 ISDVVLSSDGNYALSGSWDKTLRLWDLAAGK---TTRRFEDHTKDVLSVAFSVDNRQIVS 478
+S + + S G Y L+ TLR+W+ A+G+ T + +++ + +++
Sbjct: 274 VSQLGVKSPGLYFLTAGDQGTLRVWEAASGQCVYTQAQPPGPGRELTHCTLAHTAGVVLT 333
Query: 479 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 658
+ D + L+ + Q G+S+ V VRF + ++V+ +KV+ L
Sbjct: 334 ATADHNLLLYEA-RSLRLQKQFAGYSEEVLDVRFLGPEDSHVVVASN-SPCLKVFELQTS 391
Query: 659 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLN 778
+I H GH+ + + V G L AS KD +W +N
Sbjct: 392 ACQILH-GHTDIVLALDVFRKGWLFASCAKDQSVRIWRMN 430
Score = 41.5 bits (93), Expect = 0.003
Identities = 30/134 (22%), Positives = 56/134 (41%)
Frame = +2
Query: 128 KLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHF 307
+L G GH + + +P ++ ++S D T+ +W L ++ K GH
Sbjct: 536 QLLGVFSGHRRGLWCVQFSPM-DQVLATASADGTIKLWAL----QDFSC-LKTFEGHDAS 589
Query: 308 ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSR 487
+ V S G LS D ++LW + + R + H V + S + ++G+
Sbjct: 590 VLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAHEDKVWGLHCSRLDDHALTGAS 649
Query: 488 DKTIKLWNTLAECK 529
D + LW + E +
Sbjct: 650 DSRVILWKDVTEAE 663
Score = 40.7 bits (91), Expect = 0.006
Identities = 28/89 (31%), Positives = 45/89 (50%), Gaps = 1/89 (1%)
Frame = +2
Query: 146 RGHNGWVTQIATNPKYPDMIL-SSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
RG G V +A +P ++L SS+ D + VW L +D + + L H ++ +
Sbjct: 172 RGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWSL-QDRSCLAV----LTAHYSAVTSLA 226
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTR 409
S+DG+ LS DK +WDL + + TR
Sbjct: 227 FSADGHTMLSSGRDKICIIWDLQSCQATR 255
Score = 37.9 bits (84), Expect = 0.042
Identities = 28/124 (22%), Positives = 53/124 (42%), Gaps = 2/124 (1%)
Frame = +2
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIV 475
H+ ++ + +G D +R+WD+ T F V VAF D +++
Sbjct: 132 HTAPVATMAFDPTSTLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLL 191
Query: 476 --SGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 649
S + D I++W +L + H V+ + FS + ++S G D+ +W L
Sbjct: 192 LFSSATDAAIRVW-SLQDRSCLAVLTAHYSAVTSLAFSAD--GHTMLSSGRDKICIIWDL 248
Query: 650 TNCK 661
+C+
Sbjct: 249 QSCQ 252
>BC026213-1|AAH26213.1| 529|Homo sapiens F-box and WD repeat domain
containing 11 protein.
Length = 529
Score = 76.6 bits (180), Expect = 1e-13
Identities = 58/198 (29%), Positives = 91/198 (45%), Gaps = 2/198 (1%)
Frame = +2
Query: 197 DMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLR 376
+ I+S RD ++ +W T E K L GH+ + + L D ++GS D T+R
Sbjct: 238 EKIISGLRDNSIKIWDKTSLEC-----LKVLTGHTGSV--LCLQYDERVIVTGSSDSTVR 290
Query: 377 LWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDD--G 550
+WD+ G+ H + VL + FS N +V+ S+D++I +W+ + T++ G
Sbjct: 291 VWDVNTGEVLNTLIHHNEAVLHLRFS--NGLMVTCSKDRSIAVWDMASATDITLRRVLVG 348
Query: 551 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSL 730
H V+ V F + IVS DRT+KVW + C+ GH + L
Sbjct: 349 HRAAVNVVDFDDKY----IVSASGDRTIKVWSTSTCEFVRTLNGHK--RGIACLQYRDRL 402
Query: 731 CASGGKDMXAMLWDLNDG 784
SG D LWD+ G
Sbjct: 403 VVSGSSDNTIRLWDIECG 420
Score = 73.7 bits (173), Expect = 7e-13
Identities = 46/152 (30%), Positives = 82/152 (53%), Gaps = 2/152 (1%)
Frame = +2
Query: 200 MILSSSRDKTLIVWKLTRDENNYGIPQKR-LYGHSHFISDVVLSSDGNYALSGSWDKTLR 376
++++ S+D+++ VW + + I +R L GH ++ V+ D Y +S S D+T++
Sbjct: 319 LMVTCSKDRSIAVWDMASATD---ITLRRVLVGHRAAVN--VVDFDDKYIVSASGDRTIK 373
Query: 377 LWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQD-DGH 553
+W + + R H + + + + +R +VSGS D TI+LW+ EC ++ +GH
Sbjct: 374 VWSTSTCEFVRTLNGHKRGIACLQYR--DRLVVSGSSDNTIRLWDI--ECGACLRVLEGH 429
Query: 554 SDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 649
+ V C+RF N IVS +D +KVW L
Sbjct: 430 EELVRCIRFD----NKRIVSGAYDGKIKVWDL 457
Score = 66.9 bits (156), Expect = 8e-11
Identities = 47/132 (35%), Positives = 67/132 (50%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSH 304
+ LR L GH V + + KY I+S+S D+T+ VW + E + L GH
Sbjct: 340 ITLRRVLVGHRAAVNVVDFDDKY---IVSASGDRTIKVWSTSTCEF-----VRTLNGHKR 391
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGS 484
I+ L +SGS D T+RLWD+ G R E H + V + F DN++IVSG+
Sbjct: 392 GIA--CLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGA 447
Query: 485 RDKTIKLWNTLA 520
D IK+W+ A
Sbjct: 448 YDGKIKVWDLQA 459
Score = 62.1 bits (144), Expect = 2e-09
Identities = 45/153 (29%), Positives = 76/153 (49%), Gaps = 4/153 (2%)
Frame = +2
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
L D +SG D ++++WD + + + HT VL + + D R IV+GS D T++
Sbjct: 233 LQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQY--DERVIVTGSSDSTVR 290
Query: 503 LWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL---TNCKLKI 670
+W+ E T+ H++ V +RFS N ++V+C DR++ VW + T+ L+
Sbjct: 291 VWDVNTGEVLNTLIH--HNEAVLHLRFS----NGLMVTCSKDRSIAVWDMASATDITLRR 344
Query: 671 NHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
+GH +N V + ASG D +W
Sbjct: 345 VLVGHRAAVNVVDFDDKYIVSASG--DRTIKVW 375
Score = 46.0 bits (104), Expect = 2e-04
Identities = 31/107 (28%), Positives = 54/107 (50%), Gaps = 1/107 (0%)
Frame = +2
Query: 458 DNRQIVSGSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTV 634
D+ +I+SG RD +IK+W+ T EC + GH+ V C+++ +IV+ D TV
Sbjct: 236 DDEKIISGLRDNSIKIWDKTSLECLKVL--TGHTGSVLCLQYDER----VIVTGSSDSTV 289
Query: 635 KVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
+VW + ++ +N L H + + L + KD +WD+
Sbjct: 290 RVWDVNTGEV-LNTLIHHNEA-VLHLRFSNGLMVTCSKDRSIAVWDM 334
Score = 43.2 bits (97), Expect = 0.001
Identities = 38/144 (26%), Positives = 64/144 (44%), Gaps = 10/144 (6%)
Frame = +2
Query: 116 SETLKLRGTLRGHNGWVTQIATNPKYPD-MILSSSRDKTLIVWKLTRDENNYGIPQKRLY 292
+ T + TL GH + + +Y D +++S S D T+ +W + G + L
Sbjct: 377 TSTCEFVRTLNGHKRGIACL----QYRDRLVVSGSSDNTIRLWDI-----ECGACLRVLE 427
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRR---------FEDHTKDVLSV 445
GH + + D +SG++D +++WDL A R +H+ V +
Sbjct: 428 GHEELVR--CIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRL 485
Query: 446 AFSVDNRQIVSGSRDKTIKLWNTL 517
F D QI+S S D TI +W+ L
Sbjct: 486 QF--DEFQIISSSHDDTILIWDFL 507
>BC010080-1|AAH10080.1| 305|Homo sapiens WD repeat domain 61
protein.
Length = 305
Score = 76.6 bits (180), Expect = 1e-13
Identities = 48/157 (30%), Positives = 75/157 (47%), Gaps = 1/157 (0%)
Frame = +2
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGS 484
FI + S DG Y SG+ D + ++D+A GK E H + S+ FS D++ +V+ S
Sbjct: 150 FILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTAS 209
Query: 485 RDKTIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 661
D IK+++ A T+ GH+ WV V F P+ + VS D++VKVW +
Sbjct: 210 DDGYIKIYDVQHANLAGTL--SGHASWVLNVAFCPDDTH--FVSSSSDKSVKVWDVGTRT 265
Query: 662 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
H + V + +GS S G D ++D
Sbjct: 266 CVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIYD 302
Score = 71.7 bits (168), Expect = 3e-12
Identities = 57/235 (24%), Positives = 106/235 (45%)
Frame = +2
Query: 92 LFKPFSKMSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYG 271
L K + E L L+ +L GH V + + P + SSS D + +W L EN
Sbjct: 43 LVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLP-IAASSSLDAHIRLWDL---ENGKQ 98
Query: 272 IPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAF 451
I K + + S D Y +G+ + ++ + +GK + K +LS+A+
Sbjct: 99 I--KSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAY 156
Query: 452 SVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRT 631
S D + + SG+ D I +++ +A K +GH+ + + FSP+ + ++V+ D
Sbjct: 157 SPDGKYLASGAIDGIINIFD-IATGKLLHTLEGHAMPIRSLTFSPD--SQLLVTASDDGY 213
Query: 632 VKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
+K++ + + L GH+ ++ V PD + S D +WD+ +H
Sbjct: 214 IKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVH 268
Score = 65.3 bits (152), Expect = 2e-10
Identities = 53/207 (25%), Positives = 94/207 (45%), Gaps = 2/207 (0%)
Frame = +2
Query: 161 WVTQIATNPKY-PDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDG 337
W TN K + +++ S D + VWK RDE Q L GH + V +S
Sbjct: 20 WSVAWGTNKKENSETVVTGSLDDLVKVWKW-RDERLD--LQWSLEGHQLGVVSVDISHTL 76
Query: 338 NYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTL 517
A S S D +RLWDL GK + + D ++AFS D++ + +G+ + ++
Sbjct: 77 PIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVE 136
Query: 518 AECK-YTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGY 694
+ K Y++ D ++ + +SP+ + S D + ++ + KL GH+
Sbjct: 137 SGKKEYSL--DTRGKFILSIAYSPD--GKYLASGAIDGIINIFDIATGKLLHTLEGHAMP 192
Query: 695 LNTVTVSPDGSLCASGGKDMXAMLWDL 775
+ ++T SPD L + D ++D+
Sbjct: 193 IRSLTFSPDSQLLVTASDDGYIKIYDV 219
Score = 57.6 bits (133), Expect = 5e-08
Identities = 36/120 (30%), Positives = 60/120 (50%), Gaps = 1/120 (0%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNR 466
L GH+ I + S D ++ S D ++++D+ H VL+VAF D+
Sbjct: 186 LEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDT 245
Query: 467 QIVSGSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVW 643
VS S DK++K+W+ C +T D H D V V+++ N + IVS G D+ + ++
Sbjct: 246 HFVSSSSDKSVKVWDVGTRTCVHTFFD--HQDQVWGVKYNGNGSK--IVSVGDDQEIHIY 301
Score = 49.6 bits (113), Expect = 1e-05
Identities = 33/130 (25%), Positives = 65/130 (50%)
Frame = +2
Query: 122 TLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHS 301
T KL TL GH + + +P +++++S D + ++ + + N G L GH+
Sbjct: 179 TGKLLHTLEGHAMPIRSLTFSPD-SQLLVTASDDGYIKIYDV-QHANLAGT----LSGHA 232
Query: 302 HFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSG 481
++ +V D + +S S DK++++WD+ F DH V V ++ + +IVS
Sbjct: 233 SWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSV 292
Query: 482 SRDKTIKLWN 511
D+ I +++
Sbjct: 293 GDDQEIHIYD 302
>AK024754-1|BAB14986.1| 305|Homo sapiens protein ( Homo sapiens
cDNA: FLJ21101 fis, clone CAS04682. ).
Length = 305
Score = 76.6 bits (180), Expect = 1e-13
Identities = 48/157 (30%), Positives = 75/157 (47%), Gaps = 1/157 (0%)
Frame = +2
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGS 484
FI + S DG Y SG+ D + ++D+A GK E H + S+ FS D++ +V+ S
Sbjct: 150 FILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTAS 209
Query: 485 RDKTIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 661
D IK+++ A T+ GH+ WV V F P+ + VS D++VKVW +
Sbjct: 210 DDGYIKIYDVQHANLAGTL--SGHASWVLNVAFCPDDTH--FVSSSSDKSVKVWDVGTRT 265
Query: 662 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
H + V + +GS S G D ++D
Sbjct: 266 CVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIYD 302
Score = 71.7 bits (168), Expect = 3e-12
Identities = 57/235 (24%), Positives = 106/235 (45%)
Frame = +2
Query: 92 LFKPFSKMSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYG 271
L K + E L L+ +L GH V + + P + SSS D + +W L EN
Sbjct: 43 LVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLP-IAASSSLDAHIRLWDL---ENGKQ 98
Query: 272 IPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAF 451
I K + + S D Y +G+ + ++ + +GK + K +LS+A+
Sbjct: 99 I--KSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAY 156
Query: 452 SVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRT 631
S D + + SG+ D I +++ +A K +GH+ + + FSP+ + ++V+ D
Sbjct: 157 SPDGKYLASGAIDGIINIFD-IATGKLLHTLEGHAMPIRSLTFSPD--SQLLVTASDDGY 213
Query: 632 VKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
+K++ + + L GH+ ++ V PD + S D +WD+ +H
Sbjct: 214 IKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVH 268
Score = 65.3 bits (152), Expect = 2e-10
Identities = 53/207 (25%), Positives = 94/207 (45%), Gaps = 2/207 (0%)
Frame = +2
Query: 161 WVTQIATNPKY-PDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDG 337
W TN K + +++ S D + VWK RDE Q L GH + V +S
Sbjct: 20 WSVAWGTNKKENSETVVTGSLDDLVKVWKW-RDERLD--LQWSLEGHQLGVVSVDISHTL 76
Query: 338 NYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTL 517
A S S D +RLWDL GK + + D ++AFS D++ + +G+ + ++
Sbjct: 77 PIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVE 136
Query: 518 AECK-YTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGY 694
+ K Y++ D ++ + +SP+ + S D + ++ + KL GH+
Sbjct: 137 SGKKEYSL--DTRGKFILSIAYSPD--GKYLASGAIDGIINIFDIATGKLLHTLEGHAMP 192
Query: 695 LNTVTVSPDGSLCASGGKDMXAMLWDL 775
+ ++T SPD L + D ++D+
Sbjct: 193 IRSLTFSPDSQLLVTASDDGYIKIYDV 219
Score = 57.6 bits (133), Expect = 5e-08
Identities = 36/120 (30%), Positives = 60/120 (50%), Gaps = 1/120 (0%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNR 466
L GH+ I + S D ++ S D ++++D+ H VL+VAF D+
Sbjct: 186 LEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDT 245
Query: 467 QIVSGSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVW 643
VS S DK++K+W+ C +T D H D V V+++ N + IVS G D+ + ++
Sbjct: 246 HFVSSSSDKSVKVWDVGTRTCVHTFFD--HQDQVWGVKYNGNGSK--IVSVGDDQEIHIY 301
Score = 49.6 bits (113), Expect = 1e-05
Identities = 33/130 (25%), Positives = 65/130 (50%)
Frame = +2
Query: 122 TLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHS 301
T KL TL GH + + +P +++++S D + ++ + + N G L GH+
Sbjct: 179 TGKLLHTLEGHAMPIRSLTFSPD-SQLLVTASDDGYIKIYDV-QHANLAGT----LSGHA 232
Query: 302 HFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSG 481
++ +V D + +S S DK++++WD+ F DH V V ++ + +IVS
Sbjct: 233 SWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSV 292
Query: 482 SRDKTIKLWN 511
D+ I +++
Sbjct: 293 GDDQEIHIYD 302
>AF309553-1|AAG31639.1| 305|Homo sapiens meiotic recombination
protein REC14 protein.
Length = 305
Score = 76.6 bits (180), Expect = 1e-13
Identities = 48/157 (30%), Positives = 75/157 (47%), Gaps = 1/157 (0%)
Frame = +2
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGS 484
FI + S DG Y SG+ D + ++D+A GK E H + S+ FS D++ +V+ S
Sbjct: 150 FILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTAS 209
Query: 485 RDKTIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 661
D IK+++ A T+ GH+ WV V F P+ + VS D++VKVW +
Sbjct: 210 DDGYIKIYDVQHANLAGTL--SGHASWVLNVAFCPDDTH--FVSSSSDKSVKVWDVGTRT 265
Query: 662 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
H + V + +GS S G D ++D
Sbjct: 266 CVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIYD 302
Score = 71.7 bits (168), Expect = 3e-12
Identities = 57/235 (24%), Positives = 106/235 (45%)
Frame = +2
Query: 92 LFKPFSKMSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYG 271
L K + E L L+ +L GH V + + P + SSS D + +W L EN
Sbjct: 43 LVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLP-IAASSSLDAHIRLWDL---ENGKQ 98
Query: 272 IPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAF 451
I K + + S D Y +G+ + ++ + +GK + K +LS+A+
Sbjct: 99 I--KSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAY 156
Query: 452 SVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRT 631
S D + + SG+ D I +++ +A K +GH+ + + FSP+ + ++V+ D
Sbjct: 157 SPDGKYLASGAIDGIINIFD-IATGKLLHTLEGHAMPIRSLTFSPD--SQLLVTASDDGY 213
Query: 632 VKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
+K++ + + L GH+ ++ V PD + S D +WD+ +H
Sbjct: 214 IKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVH 268
Score = 65.3 bits (152), Expect = 2e-10
Identities = 53/207 (25%), Positives = 94/207 (45%), Gaps = 2/207 (0%)
Frame = +2
Query: 161 WVTQIATNPKY-PDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDG 337
W TN K + +++ S D + VWK RDE Q L GH + V +S
Sbjct: 20 WSVAWGTNKKENSETVVTGSLDDLVKVWKW-RDERLD--LQWSLEGHQLGVVSVDISHTL 76
Query: 338 NYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTL 517
A S S D +RLWDL GK + + D ++AFS D++ + +G+ + ++
Sbjct: 77 PIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVE 136
Query: 518 AECK-YTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGY 694
+ K Y++ D ++ + +SP+ + S D + ++ + KL GH+
Sbjct: 137 SGKKEYSL--DTRGKFILSIAYSPD--GKYLASGAIDGIINIFDIATGKLLHTLEGHAMP 192
Query: 695 LNTVTVSPDGSLCASGGKDMXAMLWDL 775
+ ++T SPD L + D ++D+
Sbjct: 193 IRSLTFSPDSQLLVTASDDGYIKIYDV 219
Score = 57.6 bits (133), Expect = 5e-08
Identities = 36/120 (30%), Positives = 60/120 (50%), Gaps = 1/120 (0%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNR 466
L GH+ I + S D ++ S D ++++D+ H VL+VAF D+
Sbjct: 186 LEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDT 245
Query: 467 QIVSGSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVW 643
VS S DK++K+W+ C +T D H D V V+++ N + IVS G D+ + ++
Sbjct: 246 HFVSSSSDKSVKVWDVGTRTCVHTFFD--HQDQVWGVKYNGNGSK--IVSVGDDQEIHIY 301
Score = 49.6 bits (113), Expect = 1e-05
Identities = 33/130 (25%), Positives = 65/130 (50%)
Frame = +2
Query: 122 TLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHS 301
T KL TL GH + + +P +++++S D + ++ + + N G L GH+
Sbjct: 179 TGKLLHTLEGHAMPIRSLTFSPD-SQLLVTASDDGYIKIYDV-QHANLAGT----LSGHA 232
Query: 302 HFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSG 481
++ +V D + +S S DK++++WD+ F DH V V ++ + +IVS
Sbjct: 233 SWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSV 292
Query: 482 SRDKTIKLWN 511
D+ I +++
Sbjct: 293 GDDQEIHIYD 302
>AF176022-1|AAF04528.1| 542|Homo sapiens F-box protein Fbw1b
protein.
Length = 542
Score = 76.6 bits (180), Expect = 1e-13
Identities = 58/198 (29%), Positives = 91/198 (45%), Gaps = 2/198 (1%)
Frame = +2
Query: 197 DMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLR 376
+ I+S RD ++ +W T E K L GH+ + + L D ++GS D T+R
Sbjct: 251 EKIISGLRDNSIKIWDKTSLEC-----LKVLTGHTGSV--LCLQYDERVIVTGSSDSTVR 303
Query: 377 LWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDD--G 550
+WD+ G+ H + VL + FS N +V+ S+D++I +W+ + T++ G
Sbjct: 304 VWDVNTGEVLNTLIHHNEAVLHLRFS--NGLMVTCSKDRSIAVWDMASATDITLRRVLVG 361
Query: 551 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSL 730
H V+ V F + IVS DRT+KVW + C+ GH + L
Sbjct: 362 HRAAVNVVDFDDKY----IVSASGDRTIKVWSTSTCEFVRTLNGHK--RGIACLQYRDRL 415
Query: 731 CASGGKDMXAMLWDLNDG 784
SG D LWD+ G
Sbjct: 416 VVSGSSDNTIRLWDIECG 433
Score = 73.7 bits (173), Expect = 7e-13
Identities = 46/152 (30%), Positives = 82/152 (53%), Gaps = 2/152 (1%)
Frame = +2
Query: 200 MILSSSRDKTLIVWKLTRDENNYGIPQKR-LYGHSHFISDVVLSSDGNYALSGSWDKTLR 376
++++ S+D+++ VW + + I +R L GH ++ V+ D Y +S S D+T++
Sbjct: 332 LMVTCSKDRSIAVWDMASATD---ITLRRVLVGHRAAVN--VVDFDDKYIVSASGDRTIK 386
Query: 377 LWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQD-DGH 553
+W + + R H + + + + +R +VSGS D TI+LW+ EC ++ +GH
Sbjct: 387 VWSTSTCEFVRTLNGHKRGIACLQYR--DRLVVSGSSDNTIRLWDI--ECGACLRVLEGH 442
Query: 554 SDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 649
+ V C+RF N IVS +D +KVW L
Sbjct: 443 EELVRCIRFD----NKRIVSGAYDGKIKVWDL 470
Score = 66.9 bits (156), Expect = 8e-11
Identities = 47/132 (35%), Positives = 67/132 (50%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSH 304
+ LR L GH V + + KY I+S+S D+T+ VW + E + L GH
Sbjct: 353 ITLRRVLVGHRAAVNVVDFDDKY---IVSASGDRTIKVWSTSTCEF-----VRTLNGHKR 404
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGS 484
I+ L +SGS D T+RLWD+ G R E H + V + F DN++IVSG+
Sbjct: 405 GIA--CLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGA 460
Query: 485 RDKTIKLWNTLA 520
D IK+W+ A
Sbjct: 461 YDGKIKVWDLQA 472
Score = 62.1 bits (144), Expect = 2e-09
Identities = 45/153 (29%), Positives = 76/153 (49%), Gaps = 4/153 (2%)
Frame = +2
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
L D +SG D ++++WD + + + HT VL + + D R IV+GS D T++
Sbjct: 246 LQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQY--DERVIVTGSSDSTVR 303
Query: 503 LWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL---TNCKLKI 670
+W+ E T+ H++ V +RFS N ++V+C DR++ VW + T+ L+
Sbjct: 304 VWDVNTGEVLNTLIH--HNEAVLHLRFS----NGLMVTCSKDRSIAVWDMASATDITLRR 357
Query: 671 NHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
+GH +N V + ASG D +W
Sbjct: 358 VLVGHRAAVNVVDFDDKYIVSASG--DRTIKVW 388
Score = 46.0 bits (104), Expect = 2e-04
Identities = 31/107 (28%), Positives = 54/107 (50%), Gaps = 1/107 (0%)
Frame = +2
Query: 458 DNRQIVSGSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTV 634
D+ +I+SG RD +IK+W+ T EC + GH+ V C+++ +IV+ D TV
Sbjct: 249 DDEKIISGLRDNSIKIWDKTSLECLKVL--TGHTGSVLCLQYDER----VIVTGSSDSTV 302
Query: 635 KVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
+VW + ++ +N L H + + L + KD +WD+
Sbjct: 303 RVWDVNTGEV-LNTLIHHNEA-VLHLRFSNGLMVTCSKDRSIAVWDM 347
Score = 43.2 bits (97), Expect = 0.001
Identities = 38/144 (26%), Positives = 64/144 (44%), Gaps = 10/144 (6%)
Frame = +2
Query: 116 SETLKLRGTLRGHNGWVTQIATNPKYPD-MILSSSRDKTLIVWKLTRDENNYGIPQKRLY 292
+ T + TL GH + + +Y D +++S S D T+ +W + G + L
Sbjct: 390 TSTCEFVRTLNGHKRGIACL----QYRDRLVVSGSSDNTIRLWDI-----ECGACLRVLE 440
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRR---------FEDHTKDVLSV 445
GH + + D +SG++D +++WDL A R +H+ V +
Sbjct: 441 GHEELVR--CIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRL 498
Query: 446 AFSVDNRQIVSGSRDKTIKLWNTL 517
F D QI+S S D TI +W+ L
Sbjct: 499 QF--DEFQIISSSHDDTILIWDFL 520
>AF100786-1|AAP97225.1| 305|Homo sapiens G protein beta
subunit-like protein protein.
Length = 305
Score = 76.6 bits (180), Expect = 1e-13
Identities = 48/157 (30%), Positives = 75/157 (47%), Gaps = 1/157 (0%)
Frame = +2
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGS 484
FI + S DG Y SG+ D + ++D+A GK E H + S+ FS D++ +V+ S
Sbjct: 150 FILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTAS 209
Query: 485 RDKTIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 661
D IK+++ A T+ GH+ WV V F P+ + VS D++VKVW +
Sbjct: 210 DDGYIKIYDVQHANLAGTL--SGHASWVLNVAFCPDDTH--FVSSSSDKSVKVWDVGTRT 265
Query: 662 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
H + V + +GS S G D ++D
Sbjct: 266 CVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIYD 302
Score = 71.7 bits (168), Expect = 3e-12
Identities = 57/235 (24%), Positives = 106/235 (45%)
Frame = +2
Query: 92 LFKPFSKMSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYG 271
L K + E L L+ +L GH V + + P + SSS D + +W L EN
Sbjct: 43 LVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLP-IAASSSLDAHIRLWDL---ENGKQ 98
Query: 272 IPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAF 451
I K + + S D Y +G+ + ++ + +GK + K +LS+A+
Sbjct: 99 I--KSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAY 156
Query: 452 SVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRT 631
S D + + SG+ D I +++ +A K +GH+ + + FSP+ + ++V+ D
Sbjct: 157 SPDGKYLASGAIDGIINIFD-IATGKLLHTLEGHAMPIRSLTFSPD--SQLLVTASDDGY 213
Query: 632 VKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
+K++ + + L GH+ ++ V PD + S D +WD+ +H
Sbjct: 214 IKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVH 268
Score = 65.3 bits (152), Expect = 2e-10
Identities = 53/207 (25%), Positives = 94/207 (45%), Gaps = 2/207 (0%)
Frame = +2
Query: 161 WVTQIATNPKY-PDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDG 337
W TN K + +++ S D + VWK RDE Q L GH + V +S
Sbjct: 20 WSVAWGTNKKENSETVVTGSLDDLVKVWKW-RDERLD--LQWSLEGHQLGVVSVDISHTL 76
Query: 338 NYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTL 517
A S S D +RLWDL GK + + D ++AFS D++ + +G+ + ++
Sbjct: 77 PIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVE 136
Query: 518 AECK-YTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGY 694
+ K Y++ D ++ + +SP+ + S D + ++ + KL GH+
Sbjct: 137 SGKKEYSL--DTRGKFILSIAYSPD--GKYLASGAIDGIINIFDIATGKLLHTLEGHAMP 192
Query: 695 LNTVTVSPDGSLCASGGKDMXAMLWDL 775
+ ++T SPD L + D ++D+
Sbjct: 193 IRSLTFSPDSQLLVTASDDGYIKIYDV 219
Score = 57.6 bits (133), Expect = 5e-08
Identities = 36/120 (30%), Positives = 60/120 (50%), Gaps = 1/120 (0%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNR 466
L GH+ I + S D ++ S D ++++D+ H VL+VAF D+
Sbjct: 186 LEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDT 245
Query: 467 QIVSGSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVW 643
VS S DK++K+W+ C +T D H D V V+++ N + IVS G D+ + ++
Sbjct: 246 HFVSSSSDKSVKVWDVGTRTCVHTFFD--HQDQVWGVKYNGNGSK--IVSVGDDQEIHIY 301
Score = 49.6 bits (113), Expect = 1e-05
Identities = 33/130 (25%), Positives = 65/130 (50%)
Frame = +2
Query: 122 TLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHS 301
T KL TL GH + + +P +++++S D + ++ + + N G L GH+
Sbjct: 179 TGKLLHTLEGHAMPIRSLTFSPD-SQLLVTASDDGYIKIYDV-QHANLAGT----LSGHA 232
Query: 302 HFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSG 481
++ +V D + +S S DK++++WD+ F DH V V ++ + +IVS
Sbjct: 233 SWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSV 292
Query: 482 SRDKTIKLWN 511
D+ I +++
Sbjct: 293 GDDQEIHIYD 302
>AB033281-1|BAA92331.1| 542|Homo sapiens F-box and WD-repeats
protein beta-TRCP2 isoform C protein.
Length = 542
Score = 76.6 bits (180), Expect = 1e-13
Identities = 58/198 (29%), Positives = 91/198 (45%), Gaps = 2/198 (1%)
Frame = +2
Query: 197 DMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLR 376
+ I+S RD ++ +W T E K L GH+ + + L D ++GS D T+R
Sbjct: 251 EKIISGLRDNSIKIWDKTSLEC-----LKVLTGHTGSV--LCLQYDERVIVTGSSDSTVR 303
Query: 377 LWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDD--G 550
+WD+ G+ H + VL + FS N +V+ S+D++I +W+ + T++ G
Sbjct: 304 VWDVNTGEVLNTLIHHNEAVLHLRFS--NGLMVTCSKDRSIAVWDMASATDITLRRVLVG 361
Query: 551 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSL 730
H V+ V F + IVS DRT+KVW + C+ GH + L
Sbjct: 362 HRAAVNVVDFDDKY----IVSASGDRTIKVWSTSTCEFVRTLNGHK--RGIACLQYRDRL 415
Query: 731 CASGGKDMXAMLWDLNDG 784
SG D LWD+ G
Sbjct: 416 VVSGSSDNTIRLWDIECG 433
Score = 73.7 bits (173), Expect = 7e-13
Identities = 46/152 (30%), Positives = 82/152 (53%), Gaps = 2/152 (1%)
Frame = +2
Query: 200 MILSSSRDKTLIVWKLTRDENNYGIPQKR-LYGHSHFISDVVLSSDGNYALSGSWDKTLR 376
++++ S+D+++ VW + + I +R L GH ++ V+ D Y +S S D+T++
Sbjct: 332 LMVTCSKDRSIAVWDMASATD---ITLRRVLVGHRAAVN--VVDFDDKYIVSASGDRTIK 386
Query: 377 LWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQD-DGH 553
+W + + R H + + + + +R +VSGS D TI+LW+ EC ++ +GH
Sbjct: 387 VWSTSTCEFVRTLNGHKRGIACLQYR--DRLVVSGSSDNTIRLWDI--ECGACLRVLEGH 442
Query: 554 SDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 649
+ V C+RF N IVS +D +KVW L
Sbjct: 443 EELVRCIRFD----NKRIVSGAYDGKIKVWDL 470
Score = 66.9 bits (156), Expect = 8e-11
Identities = 47/132 (35%), Positives = 67/132 (50%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSH 304
+ LR L GH V + + KY I+S+S D+T+ VW + E + L GH
Sbjct: 353 ITLRRVLVGHRAAVNVVDFDDKY---IVSASGDRTIKVWSTSTCEF-----VRTLNGHKR 404
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGS 484
I+ L +SGS D T+RLWD+ G R E H + V + F DN++IVSG+
Sbjct: 405 GIA--CLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGA 460
Query: 485 RDKTIKLWNTLA 520
D IK+W+ A
Sbjct: 461 YDGKIKVWDLQA 472
Score = 62.1 bits (144), Expect = 2e-09
Identities = 45/153 (29%), Positives = 76/153 (49%), Gaps = 4/153 (2%)
Frame = +2
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
L D +SG D ++++WD + + + HT VL + + D R IV+GS D T++
Sbjct: 246 LQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQY--DERVIVTGSSDSTVR 303
Query: 503 LWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL---TNCKLKI 670
+W+ E T+ H++ V +RFS N ++V+C DR++ VW + T+ L+
Sbjct: 304 VWDVNTGEVLNTLIH--HNEAVLHLRFS----NGLMVTCSKDRSIAVWDMASATDITLRR 357
Query: 671 NHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
+GH +N V + ASG D +W
Sbjct: 358 VLVGHRAAVNVVDFDDKYIVSASG--DRTIKVW 388
Score = 46.0 bits (104), Expect = 2e-04
Identities = 31/107 (28%), Positives = 54/107 (50%), Gaps = 1/107 (0%)
Frame = +2
Query: 458 DNRQIVSGSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTV 634
D+ +I+SG RD +IK+W+ T EC + GH+ V C+++ +IV+ D TV
Sbjct: 249 DDEKIISGLRDNSIKIWDKTSLECLKVL--TGHTGSVLCLQYDER----VIVTGSSDSTV 302
Query: 635 KVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
+VW + ++ +N L H + + L + KD +WD+
Sbjct: 303 RVWDVNTGEV-LNTLIHHNEA-VLHLRFSNGLMVTCSKDRSIAVWDM 347
Score = 43.2 bits (97), Expect = 0.001
Identities = 38/144 (26%), Positives = 64/144 (44%), Gaps = 10/144 (6%)
Frame = +2
Query: 116 SETLKLRGTLRGHNGWVTQIATNPKYPD-MILSSSRDKTLIVWKLTRDENNYGIPQKRLY 292
+ T + TL GH + + +Y D +++S S D T+ +W + G + L
Sbjct: 390 TSTCEFVRTLNGHKRGIACL----QYRDRLVVSGSSDNTIRLWDI-----ECGACLRVLE 440
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRR---------FEDHTKDVLSV 445
GH + + D +SG++D +++WDL A R +H+ V +
Sbjct: 441 GHEELVR--CIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRL 498
Query: 446 AFSVDNRQIVSGSRDKTIKLWNTL 517
F D QI+S S D TI +W+ L
Sbjct: 499 QF--DEFQIISSSHDDTILIWDFL 520
>AB033280-1|BAA92330.1| 529|Homo sapiens F-box and WD-repeats
protein beta-TRCP2 isoform B protein.
Length = 529
Score = 76.6 bits (180), Expect = 1e-13
Identities = 58/198 (29%), Positives = 91/198 (45%), Gaps = 2/198 (1%)
Frame = +2
Query: 197 DMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLR 376
+ I+S RD ++ +W T E K L GH+ + + L D ++GS D T+R
Sbjct: 238 EKIISGLRDNSIKIWDKTSLEC-----LKVLTGHTGSV--LCLQYDERVIVTGSSDSTVR 290
Query: 377 LWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDD--G 550
+WD+ G+ H + VL + FS N +V+ S+D++I +W+ + T++ G
Sbjct: 291 VWDVNTGEVLNTLIHHNEAVLHLRFS--NGLMVTCSKDRSIAVWDMASATDITLRRVLVG 348
Query: 551 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSL 730
H V+ V F + IVS DRT+KVW + C+ GH + L
Sbjct: 349 HRAAVNVVDFDDKY----IVSASGDRTIKVWSTSTCEFVRTLNGHK--RGIACLQYRDRL 402
Query: 731 CASGGKDMXAMLWDLNDG 784
SG D LWD+ G
Sbjct: 403 VVSGSSDNTIRLWDIECG 420
Score = 73.7 bits (173), Expect = 7e-13
Identities = 46/152 (30%), Positives = 82/152 (53%), Gaps = 2/152 (1%)
Frame = +2
Query: 200 MILSSSRDKTLIVWKLTRDENNYGIPQKR-LYGHSHFISDVVLSSDGNYALSGSWDKTLR 376
++++ S+D+++ VW + + I +R L GH ++ V+ D Y +S S D+T++
Sbjct: 319 LMVTCSKDRSIAVWDMASATD---ITLRRVLVGHRAAVN--VVDFDDKYIVSASGDRTIK 373
Query: 377 LWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQD-DGH 553
+W + + R H + + + + +R +VSGS D TI+LW+ EC ++ +GH
Sbjct: 374 VWSTSTCEFVRTLNGHKRGIACLQYR--DRLVVSGSSDNTIRLWDI--ECGACLRVLEGH 429
Query: 554 SDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 649
+ V C+RF N IVS +D +KVW L
Sbjct: 430 EELVRCIRFD----NKRIVSGAYDGKIKVWDL 457
Score = 66.9 bits (156), Expect = 8e-11
Identities = 47/132 (35%), Positives = 67/132 (50%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSH 304
+ LR L GH V + + KY I+S+S D+T+ VW + E + L GH
Sbjct: 340 ITLRRVLVGHRAAVNVVDFDDKY---IVSASGDRTIKVWSTSTCEF-----VRTLNGHKR 391
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGS 484
I+ L +SGS D T+RLWD+ G R E H + V + F DN++IVSG+
Sbjct: 392 GIA--CLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGA 447
Query: 485 RDKTIKLWNTLA 520
D IK+W+ A
Sbjct: 448 YDGKIKVWDLQA 459
Score = 62.1 bits (144), Expect = 2e-09
Identities = 45/153 (29%), Positives = 76/153 (49%), Gaps = 4/153 (2%)
Frame = +2
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
L D +SG D ++++WD + + + HT VL + + D R IV+GS D T++
Sbjct: 233 LQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQY--DERVIVTGSSDSTVR 290
Query: 503 LWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL---TNCKLKI 670
+W+ E T+ H++ V +RFS N ++V+C DR++ VW + T+ L+
Sbjct: 291 VWDVNTGEVLNTLIH--HNEAVLHLRFS----NGLMVTCSKDRSIAVWDMASATDITLRR 344
Query: 671 NHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
+GH +N V + ASG D +W
Sbjct: 345 VLVGHRAAVNVVDFDDKYIVSASG--DRTIKVW 375
Score = 46.0 bits (104), Expect = 2e-04
Identities = 31/107 (28%), Positives = 54/107 (50%), Gaps = 1/107 (0%)
Frame = +2
Query: 458 DNRQIVSGSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTV 634
D+ +I+SG RD +IK+W+ T EC + GH+ V C+++ +IV+ D TV
Sbjct: 236 DDEKIISGLRDNSIKIWDKTSLECLKVL--TGHTGSVLCLQYDER----VIVTGSSDSTV 289
Query: 635 KVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
+VW + ++ +N L H + + L + KD +WD+
Sbjct: 290 RVWDVNTGEV-LNTLIHHNEA-VLHLRFSNGLMVTCSKDRSIAVWDM 334
Score = 43.2 bits (97), Expect = 0.001
Identities = 38/144 (26%), Positives = 64/144 (44%), Gaps = 10/144 (6%)
Frame = +2
Query: 116 SETLKLRGTLRGHNGWVTQIATNPKYPD-MILSSSRDKTLIVWKLTRDENNYGIPQKRLY 292
+ T + TL GH + + +Y D +++S S D T+ +W + G + L
Sbjct: 377 TSTCEFVRTLNGHKRGIACL----QYRDRLVVSGSSDNTIRLWDI-----ECGACLRVLE 427
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRR---------FEDHTKDVLSV 445
GH + + D +SG++D +++WDL A R +H+ V +
Sbjct: 428 GHEELVR--CIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRL 485
Query: 446 AFSVDNRQIVSGSRDKTIKLWNTL 517
F D QI+S S D TI +W+ L
Sbjct: 486 QF--DEFQIISSSHDDTILIWDFL 507
>AB033279-1|BAA92329.1| 508|Homo sapiens F-box and WD-repeats
protein beta-TRCP2 isoform A protein.
Length = 508
Score = 76.6 bits (180), Expect = 1e-13
Identities = 58/198 (29%), Positives = 91/198 (45%), Gaps = 2/198 (1%)
Frame = +2
Query: 197 DMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLR 376
+ I+S RD ++ +W T E K L GH+ + + L D ++GS D T+R
Sbjct: 217 EKIISGLRDNSIKIWDKTSLEC-----LKVLTGHTGSV--LCLQYDERVIVTGSSDSTVR 269
Query: 377 LWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDD--G 550
+WD+ G+ H + VL + FS N +V+ S+D++I +W+ + T++ G
Sbjct: 270 VWDVNTGEVLNTLIHHNEAVLHLRFS--NGLMVTCSKDRSIAVWDMASATDITLRRVLVG 327
Query: 551 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSL 730
H V+ V F + IVS DRT+KVW + C+ GH + L
Sbjct: 328 HRAAVNVVDFDDKY----IVSASGDRTIKVWSTSTCEFVRTLNGHK--RGIACLQYRDRL 381
Query: 731 CASGGKDMXAMLWDLNDG 784
SG D LWD+ G
Sbjct: 382 VVSGSSDNTIRLWDIECG 399
Score = 73.7 bits (173), Expect = 7e-13
Identities = 46/152 (30%), Positives = 82/152 (53%), Gaps = 2/152 (1%)
Frame = +2
Query: 200 MILSSSRDKTLIVWKLTRDENNYGIPQKR-LYGHSHFISDVVLSSDGNYALSGSWDKTLR 376
++++ S+D+++ VW + + I +R L GH ++ V+ D Y +S S D+T++
Sbjct: 298 LMVTCSKDRSIAVWDMASATD---ITLRRVLVGHRAAVN--VVDFDDKYIVSASGDRTIK 352
Query: 377 LWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQD-DGH 553
+W + + R H + + + + +R +VSGS D TI+LW+ EC ++ +GH
Sbjct: 353 VWSTSTCEFVRTLNGHKRGIACLQYR--DRLVVSGSSDNTIRLWDI--ECGACLRVLEGH 408
Query: 554 SDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 649
+ V C+RF N IVS +D +KVW L
Sbjct: 409 EELVRCIRFD----NKRIVSGAYDGKIKVWDL 436
Score = 66.9 bits (156), Expect = 8e-11
Identities = 47/132 (35%), Positives = 67/132 (50%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSH 304
+ LR L GH V + + KY I+S+S D+T+ VW + E + L GH
Sbjct: 319 ITLRRVLVGHRAAVNVVDFDDKY---IVSASGDRTIKVWSTSTCEF-----VRTLNGHKR 370
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGS 484
I+ L +SGS D T+RLWD+ G R E H + V + F DN++IVSG+
Sbjct: 371 GIA--CLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGA 426
Query: 485 RDKTIKLWNTLA 520
D IK+W+ A
Sbjct: 427 YDGKIKVWDLQA 438
Score = 62.1 bits (144), Expect = 2e-09
Identities = 45/153 (29%), Positives = 76/153 (49%), Gaps = 4/153 (2%)
Frame = +2
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
L D +SG D ++++WD + + + HT VL + + D R IV+GS D T++
Sbjct: 212 LQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQY--DERVIVTGSSDSTVR 269
Query: 503 LWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL---TNCKLKI 670
+W+ E T+ H++ V +RFS N ++V+C DR++ VW + T+ L+
Sbjct: 270 VWDVNTGEVLNTLIH--HNEAVLHLRFS----NGLMVTCSKDRSIAVWDMASATDITLRR 323
Query: 671 NHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
+GH +N V + ASG D +W
Sbjct: 324 VLVGHRAAVNVVDFDDKYIVSASG--DRTIKVW 354
Score = 46.0 bits (104), Expect = 2e-04
Identities = 31/107 (28%), Positives = 54/107 (50%), Gaps = 1/107 (0%)
Frame = +2
Query: 458 DNRQIVSGSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTV 634
D+ +I+SG RD +IK+W+ T EC + GH+ V C+++ +IV+ D TV
Sbjct: 215 DDEKIISGLRDNSIKIWDKTSLECLKVL--TGHTGSVLCLQYDER----VIVTGSSDSTV 268
Query: 635 KVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
+VW + ++ +N L H + + L + KD +WD+
Sbjct: 269 RVWDVNTGEV-LNTLIHHNEA-VLHLRFSNGLMVTCSKDRSIAVWDM 313
Score = 43.2 bits (97), Expect = 0.001
Identities = 38/144 (26%), Positives = 64/144 (44%), Gaps = 10/144 (6%)
Frame = +2
Query: 116 SETLKLRGTLRGHNGWVTQIATNPKYPD-MILSSSRDKTLIVWKLTRDENNYGIPQKRLY 292
+ T + TL GH + + +Y D +++S S D T+ +W + G + L
Sbjct: 356 TSTCEFVRTLNGHKRGIACL----QYRDRLVVSGSSDNTIRLWDI-----ECGACLRVLE 406
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRR---------FEDHTKDVLSV 445
GH + + D +SG++D +++WDL A R +H+ V +
Sbjct: 407 GHEELVR--CIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRL 464
Query: 446 AFSVDNRQIVSGSRDKTIKLWNTL 517
F D QI+S S D TI +W+ L
Sbjct: 465 QF--DEFQIISSSHDDTILIWDFL 486
>AB014596-1|BAA31671.1| 550|Homo sapiens KIAA0696 protein protein.
Length = 550
Score = 76.6 bits (180), Expect = 1e-13
Identities = 58/198 (29%), Positives = 91/198 (45%), Gaps = 2/198 (1%)
Frame = +2
Query: 197 DMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLR 376
+ I+S RD ++ +W T E K L GH+ + + L D ++GS D T+R
Sbjct: 259 EKIISGLRDNSIKIWDKTSLEC-----LKVLTGHTGSV--LCLQYDERVIVTGSSDSTVR 311
Query: 377 LWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDD--G 550
+WD+ G+ H + VL + FS N +V+ S+D++I +W+ + T++ G
Sbjct: 312 VWDVNTGEVLNTLIHHNEAVLHLRFS--NGLMVTCSKDRSIAVWDMASATDITLRRVLVG 369
Query: 551 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSL 730
H V+ V F + IVS DRT+KVW + C+ GH + L
Sbjct: 370 HRAAVNVVDFDDKY----IVSASGDRTIKVWSTSTCEFVRTLNGHK--RGIACLQYRDRL 423
Query: 731 CASGGKDMXAMLWDLNDG 784
SG D LWD+ G
Sbjct: 424 VVSGSSDNTIRLWDIECG 441
Score = 73.7 bits (173), Expect = 7e-13
Identities = 46/152 (30%), Positives = 82/152 (53%), Gaps = 2/152 (1%)
Frame = +2
Query: 200 MILSSSRDKTLIVWKLTRDENNYGIPQKR-LYGHSHFISDVVLSSDGNYALSGSWDKTLR 376
++++ S+D+++ VW + + I +R L GH ++ V+ D Y +S S D+T++
Sbjct: 340 LMVTCSKDRSIAVWDMASATD---ITLRRVLVGHRAAVN--VVDFDDKYIVSASGDRTIK 394
Query: 377 LWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQD-DGH 553
+W + + R H + + + + +R +VSGS D TI+LW+ EC ++ +GH
Sbjct: 395 VWSTSTCEFVRTLNGHKRGIACLQYR--DRLVVSGSSDNTIRLWDI--ECGACLRVLEGH 450
Query: 554 SDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 649
+ V C+RF N IVS +D +KVW L
Sbjct: 451 EELVRCIRFD----NKRIVSGAYDGKIKVWDL 478
Score = 66.9 bits (156), Expect = 8e-11
Identities = 47/132 (35%), Positives = 67/132 (50%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSH 304
+ LR L GH V + + KY I+S+S D+T+ VW + E + L GH
Sbjct: 361 ITLRRVLVGHRAAVNVVDFDDKY---IVSASGDRTIKVWSTSTCEF-----VRTLNGHKR 412
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGS 484
I+ L +SGS D T+RLWD+ G R E H + V + F DN++IVSG+
Sbjct: 413 GIA--CLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGA 468
Query: 485 RDKTIKLWNTLA 520
D IK+W+ A
Sbjct: 469 YDGKIKVWDLQA 480
Score = 62.1 bits (144), Expect = 2e-09
Identities = 45/153 (29%), Positives = 76/153 (49%), Gaps = 4/153 (2%)
Frame = +2
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
L D +SG D ++++WD + + + HT VL + + D R IV+GS D T++
Sbjct: 254 LQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQY--DERVIVTGSSDSTVR 311
Query: 503 LWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL---TNCKLKI 670
+W+ E T+ H++ V +RFS N ++V+C DR++ VW + T+ L+
Sbjct: 312 VWDVNTGEVLNTLIH--HNEAVLHLRFS----NGLMVTCSKDRSIAVWDMASATDITLRR 365
Query: 671 NHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
+GH +N V + ASG D +W
Sbjct: 366 VLVGHRAAVNVVDFDDKYIVSASG--DRTIKVW 396
Score = 46.0 bits (104), Expect = 2e-04
Identities = 31/107 (28%), Positives = 54/107 (50%), Gaps = 1/107 (0%)
Frame = +2
Query: 458 DNRQIVSGSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTV 634
D+ +I+SG RD +IK+W+ T EC + GH+ V C+++ +IV+ D TV
Sbjct: 257 DDEKIISGLRDNSIKIWDKTSLECLKVL--TGHTGSVLCLQYDER----VIVTGSSDSTV 310
Query: 635 KVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
+VW + ++ +N L H + + L + KD +WD+
Sbjct: 311 RVWDVNTGEV-LNTLIHHNEA-VLHLRFSNGLMVTCSKDRSIAVWDM 355
Score = 43.2 bits (97), Expect = 0.001
Identities = 38/144 (26%), Positives = 64/144 (44%), Gaps = 10/144 (6%)
Frame = +2
Query: 116 SETLKLRGTLRGHNGWVTQIATNPKYPD-MILSSSRDKTLIVWKLTRDENNYGIPQKRLY 292
+ T + TL GH + + +Y D +++S S D T+ +W + G + L
Sbjct: 398 TSTCEFVRTLNGHKRGIACL----QYRDRLVVSGSSDNTIRLWDI-----ECGACLRVLE 448
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRR---------FEDHTKDVLSV 445
GH + + D +SG++D +++WDL A R +H+ V +
Sbjct: 449 GHEELVR--CIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRL 506
Query: 446 AFSVDNRQIVSGSRDKTIKLWNTL 517
F D QI+S S D TI +W+ L
Sbjct: 507 QF--DEFQIISSSHDDTILIWDFL 528
>AF145020-1|AAD42075.1| 649|Homo sapiens phospholipase A2
activating protein protein.
Length = 649
Score = 76.2 bits (179), Expect = 1e-13
Identities = 56/213 (26%), Positives = 97/213 (45%), Gaps = 4/213 (1%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPK---YPD-MILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFI 310
+ GH+ +V+ + P YP +I + D + + L +P L GH + +
Sbjct: 4 MSGHSNFVSCVCIIPSSDIYPHGLIFTGGNDHNICILSLDSP-----MPLYILKGHKNTV 58
Query: 311 SDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRD 490
+ G LSGSWD T ++W K + HT V +V + +++GS D
Sbjct: 59 CSLSSGKFGTL-LSGSWDTTAKVW--LNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSAD 115
Query: 491 KTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKI 670
KT+KLW C+ T GH D CVR + +SC D +++ W +T L++
Sbjct: 116 KTVKLWKA-GRCERTF--SGHED---CVRGLAILSETEFLSCANDASIRRWQITGECLEV 169
Query: 671 NHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
+ GH+ Y+ +++V P+ + +D +W
Sbjct: 170 -YYGHTNYIYSISVFPNCRDFVTTAEDRSLRIW 201
>CR457333-1|CAG33614.1| 305|Homo sapiens REC14 protein.
Length = 305
Score = 75.8 bits (178), Expect = 2e-13
Identities = 48/157 (30%), Positives = 74/157 (47%), Gaps = 1/157 (0%)
Frame = +2
Query: 305 FISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGS 484
FI + S DG Y SG+ D + ++D+A GK E H + S+ FS D++ +V+ S
Sbjct: 150 FILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTAS 209
Query: 485 RDKTIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 661
D IK+++ A T+ GH+ WV V F P+ + VS D+ VKVW +
Sbjct: 210 DDGYIKIYDVQHANLAGTL--GGHASWVLNVAFCPDDTH--FVSSSSDKNVKVWDVGTRT 265
Query: 662 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
H + V + +GS S G D ++D
Sbjct: 266 CVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIYD 302
Score = 70.5 bits (165), Expect = 6e-12
Identities = 57/235 (24%), Positives = 106/235 (45%)
Frame = +2
Query: 92 LFKPFSKMSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYG 271
L K + E L L+ +L GH V + + P + SSS D + +W L EN
Sbjct: 43 LVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLP-IAASSSLDAHIRLWDL---ENGKQ 98
Query: 272 IPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAF 451
I K + + S D Y +G+ + ++ + +GK + K +LS+A+
Sbjct: 99 I--KSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAY 156
Query: 452 SVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRT 631
S D + + SG+ D I +++ +A K +GH+ + + FSP+ + ++V+ D
Sbjct: 157 SPDGKYLASGAIDGIINIFD-IATGKLLHTLEGHAMPIRSLTFSPD--SQLLVTASDDGY 213
Query: 632 VKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
+K++ + + L GH+ ++ V PD + S D +WD+ +H
Sbjct: 214 IKIYDVQHANLAGTLGGHASWVLNVAFCPDDTHFVSSSSDKNVKVWDVGTRTCVH 268
Score = 65.3 bits (152), Expect = 2e-10
Identities = 53/207 (25%), Positives = 94/207 (45%), Gaps = 2/207 (0%)
Frame = +2
Query: 161 WVTQIATNPKY-PDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDG 337
W TN K + +++ S D + VWK RDE Q L GH + V +S
Sbjct: 20 WSVAWGTNKKENSETVVTGSLDDLVKVWKW-RDERLD--LQWSLEGHQLGVVSVDISHTL 76
Query: 338 NYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTL 517
A S S D +RLWDL GK + + D ++AFS D++ + +G+ + ++
Sbjct: 77 PIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVE 136
Query: 518 AECK-YTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGY 694
+ K Y++ D ++ + +SP+ + S D + ++ + KL GH+
Sbjct: 137 SGKKEYSL--DTRGKFILSIAYSPD--GKYLASGAIDGIINIFDIATGKLLHTLEGHAMP 192
Query: 695 LNTVTVSPDGSLCASGGKDMXAMLWDL 775
+ ++T SPD L + D ++D+
Sbjct: 193 IRSLTFSPDSQLLVTASDDGYIKIYDV 219
Score = 56.4 bits (130), Expect = 1e-07
Identities = 36/120 (30%), Positives = 59/120 (49%), Gaps = 1/120 (0%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNR 466
L GH+ I + S D ++ S D ++++D+ H VL+VAF D+
Sbjct: 186 LEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLGGHASWVLNVAFCPDDT 245
Query: 467 QIVSGSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVW 643
VS S DK +K+W+ C +T D H D V V+++ N + IVS G D+ + ++
Sbjct: 246 HFVSSSSDKNVKVWDVGTRTCVHTFFD--HQDQVWGVKYNGNGSK--IVSVGDDQEIHIY 301
Score = 48.8 bits (111), Expect = 2e-05
Identities = 33/130 (25%), Positives = 64/130 (49%)
Frame = +2
Query: 122 TLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHS 301
T KL TL GH + + +P +++++S D + ++ + + N G L GH+
Sbjct: 179 TGKLLHTLEGHAMPIRSLTFSPD-SQLLVTASDDGYIKIYDV-QHANLAGT----LGGHA 232
Query: 302 HFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSG 481
++ +V D + +S S DK +++WD+ F DH V V ++ + +IVS
Sbjct: 233 SWVLNVAFCPDDTHFVSSSSDKNVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSV 292
Query: 482 SRDKTIKLWN 511
D+ I +++
Sbjct: 293 GDDQEIHIYD 302
>BC013997-1|AAH13997.1| 353|Homo sapiens guanine nucleotide binding
protein (G protein), beta 5 protein.
Length = 353
Score = 75.8 bits (178), Expect = 2e-13
Identities = 54/191 (28%), Positives = 87/191 (45%), Gaps = 2/191 (1%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLW 382
IL++S D T +W + E+ + +G D+ S GN +SG DK +W
Sbjct: 168 ILTASGDGTCALWDV---ESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVW 224
Query: 383 DLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTI-QDDGHSD 559
D+ +G+ + FE H D+ SV + SGS D T +L++ A+ + I +
Sbjct: 225 DMRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIF 284
Query: 560 WVSCVRFSPNHANPIIVSCGW-DRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCA 736
S V FS + ++ G+ D T+ VW + GH ++T+ VSPDG+
Sbjct: 285 GASSVDFS---LSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFC 341
Query: 737 SGGKDMXAMLW 769
SG D +W
Sbjct: 342 SGSWDHTLRVW 352
Score = 64.5 bits (150), Expect = 4e-10
Identities = 59/220 (26%), Positives = 94/220 (42%), Gaps = 3/220 (1%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWK--LTRDENNYGIPQKRLYGH 298
+K R TL+GH V + K I+SSS+D +IVW T E+ +P +
Sbjct: 53 MKTRRTLKGHGNKVLCMDWC-KDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMAC 111
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVS 478
++ S ++ G + T + A K + HT + + +F+ + QI++
Sbjct: 112 AYAPSGCAIACGGLDNKCSVYPLTFDKNENMAAK-KKSVAMHTNYLSACSFTNSDMQILT 170
Query: 479 GSRDKTIKLWNTLAECKYTIQD-DGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 655
S D T LW+ E +Q GH V C+ +P+ VS G D+ VW + +
Sbjct: 171 ASGDGTCALWD--VESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRS 228
Query: 656 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
+ H +N+V P G ASG D L+DL
Sbjct: 229 GQCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDL 268
Score = 58.0 bits (134), Expect = 4e-08
Identities = 55/217 (25%), Positives = 91/217 (41%), Gaps = 6/217 (2%)
Frame = +2
Query: 161 WVTQIATNPKYPDMILSSSRDKTLIVWKLTRDEN-NYGIPQKRLYGHSHFISDVVLSSDG 337
WV A P I D V+ LT D+N N +K + H++++S ++
Sbjct: 107 WVMACAYAPS-GCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSD 165
Query: 338 NYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDV--LSVAFSVDNRQIVSGSRDKTIKLWN 511
L+ S D T LWD+ +G+ + F H DV L +A S VSG DK +W+
Sbjct: 166 MQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWD 225
Query: 512 TLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHS 688
+ +C + H ++ VR+ P + S D T +++ L + + S
Sbjct: 226 MRSGQCVQAFET--HESDINSVRYYP--SGDAFASGSDDATCRLYDLRADREVAIYSKES 281
Query: 689 GYL--NTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
++V S G L +G D +WD+ G +
Sbjct: 282 IIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRV 318
Score = 40.7 bits (91), Expect = 0.006
Identities = 35/138 (25%), Positives = 56/138 (40%), Gaps = 6/138 (4%)
Frame = +2
Query: 398 KTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVR 577
KT R + H VL + + D R+IVS S+D + +W++ K WV
Sbjct: 54 KTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAV-TMPCTWVMACA 112
Query: 578 FSPNHANPIIVSCGWDRTVKVWHLT-----NCKLKINHLG-HSGYLNTVTVSPDGSLCAS 739
++P+ I G D V+ LT N K + H+ YL+ + + +
Sbjct: 113 YAPSGC--AIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILT 170
Query: 740 GGKDMXAMLWDLNDGKHL 793
D LWD+ G+ L
Sbjct: 171 ASGDGTCALWDVESGQLL 188
>AF501885-1|AAM15921.1| 353|Homo sapiens guanine nucleotide binding
protein beta 5 protein.
Length = 353
Score = 75.8 bits (178), Expect = 2e-13
Identities = 54/191 (28%), Positives = 87/191 (45%), Gaps = 2/191 (1%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLW 382
IL++S D T +W + E+ + +G D+ S GN +SG DK +W
Sbjct: 168 ILTASGDGTCALWDV---ESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVW 224
Query: 383 DLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTI-QDDGHSD 559
D+ +G+ + FE H D+ SV + SGS D T +L++ A+ + I +
Sbjct: 225 DMRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIF 284
Query: 560 WVSCVRFSPNHANPIIVSCGW-DRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCA 736
S V FS + ++ G+ D T+ VW + GH ++T+ VSPDG+
Sbjct: 285 GASSVDFS---LSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFC 341
Query: 737 SGGKDMXAMLW 769
SG D +W
Sbjct: 342 SGSWDHTLRVW 352
Score = 64.5 bits (150), Expect = 4e-10
Identities = 59/220 (26%), Positives = 94/220 (42%), Gaps = 3/220 (1%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWK--LTRDENNYGIPQKRLYGH 298
+K R TL+GH V + K I+SSS+D +IVW T E+ +P +
Sbjct: 53 MKTRRTLKGHGNKVLCMDWC-KDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMAC 111
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVS 478
++ S ++ G + T + A K + HT + + +F+ + QI++
Sbjct: 112 AYAPSGCAIACGGLDNKCSVYPLTFDKNENMAAK-KKSVAMHTNYLSACSFTNSDMQILT 170
Query: 479 GSRDKTIKLWNTLAECKYTIQD-DGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 655
S D T LW+ E +Q GH V C+ +P+ VS G D+ VW + +
Sbjct: 171 ASGDGTCALWD--VESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRS 228
Query: 656 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
+ H +N+V P G ASG D L+DL
Sbjct: 229 GQCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDL 268
Score = 58.0 bits (134), Expect = 4e-08
Identities = 55/217 (25%), Positives = 91/217 (41%), Gaps = 6/217 (2%)
Frame = +2
Query: 161 WVTQIATNPKYPDMILSSSRDKTLIVWKLTRDEN-NYGIPQKRLYGHSHFISDVVLSSDG 337
WV A P I D V+ LT D+N N +K + H++++S ++
Sbjct: 107 WVMACAYAPS-GCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSD 165
Query: 338 NYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDV--LSVAFSVDNRQIVSGSRDKTIKLWN 511
L+ S D T LWD+ +G+ + F H DV L +A S VSG DK +W+
Sbjct: 166 MQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWD 225
Query: 512 TLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHS 688
+ +C + H ++ VR+ P + S D T +++ L + + S
Sbjct: 226 MRSGQCVQAFET--HESDINSVRYYP--SGDAFASGSDDATCRLYDLRADREVAIYSKES 281
Query: 689 GYL--NTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
++V S G L +G D +WD+ G +
Sbjct: 282 IIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRV 318
Score = 40.7 bits (91), Expect = 0.006
Identities = 35/138 (25%), Positives = 56/138 (40%), Gaps = 6/138 (4%)
Frame = +2
Query: 398 KTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVR 577
KT R + H VL + + D R+IVS S+D + +W++ K WV
Sbjct: 54 KTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAV-TMPCTWVMACA 112
Query: 578 FSPNHANPIIVSCGWDRTVKVWHLT-----NCKLKINHLG-HSGYLNTVTVSPDGSLCAS 739
++P+ I G D V+ LT N K + H+ YL+ + + +
Sbjct: 113 YAPSGC--AIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILT 170
Query: 740 GGKDMXAMLWDLNDGKHL 793
D LWD+ G+ L
Sbjct: 171 ASGDGTCALWDVESGQLL 188
>AF300650-1|AAG18444.1| 395|Homo sapiens guanine nucleotide binding
protein beta subunit 5L protein.
Length = 395
Score = 75.8 bits (178), Expect = 2e-13
Identities = 54/191 (28%), Positives = 87/191 (45%), Gaps = 2/191 (1%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLW 382
IL++S D T +W + E+ + +G D+ S GN +SG DK +W
Sbjct: 210 ILTASGDGTCALWDV---ESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVW 266
Query: 383 DLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTI-QDDGHSD 559
D+ +G+ + FE H D+ SV + SGS D T +L++ A+ + I +
Sbjct: 267 DMRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIF 326
Query: 560 WVSCVRFSPNHANPIIVSCGW-DRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCA 736
S V FS + ++ G+ D T+ VW + GH ++T+ VSPDG+
Sbjct: 327 GASSVDFS---LSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFC 383
Query: 737 SGGKDMXAMLW 769
SG D +W
Sbjct: 384 SGSWDHTLRVW 394
Score = 64.5 bits (150), Expect = 4e-10
Identities = 59/220 (26%), Positives = 94/220 (42%), Gaps = 3/220 (1%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWK--LTRDENNYGIPQKRLYGH 298
+K R TL+GH V + K I+SSS+D +IVW T E+ +P +
Sbjct: 95 MKTRRTLKGHGNKVLCMDWC-KDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMAC 153
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVS 478
++ S ++ G + T + A K + HT + + +F+ + QI++
Sbjct: 154 AYAPSGCAIACGGLDNKCSVYPLTFDKNENMAAK-KKSVAMHTNYLSACSFTNSDMQILT 212
Query: 479 GSRDKTIKLWNTLAECKYTIQD-DGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 655
S D T LW+ E +Q GH V C+ +P+ VS G D+ VW + +
Sbjct: 213 ASGDGTCALWD--VESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRS 270
Query: 656 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
+ H +N+V P G ASG D L+DL
Sbjct: 271 GQCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDL 310
Score = 58.0 bits (134), Expect = 4e-08
Identities = 55/217 (25%), Positives = 91/217 (41%), Gaps = 6/217 (2%)
Frame = +2
Query: 161 WVTQIATNPKYPDMILSSSRDKTLIVWKLTRDEN-NYGIPQKRLYGHSHFISDVVLSSDG 337
WV A P I D V+ LT D+N N +K + H++++S ++
Sbjct: 149 WVMACAYAPS-GCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSD 207
Query: 338 NYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDV--LSVAFSVDNRQIVSGSRDKTIKLWN 511
L+ S D T LWD+ +G+ + F H DV L +A S VSG DK +W+
Sbjct: 208 MQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWD 267
Query: 512 TLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHS 688
+ +C + H ++ VR+ P + S D T +++ L + + S
Sbjct: 268 MRSGQCVQAFET--HESDINSVRYYP--SGDAFASGSDDATCRLYDLRADREVAIYSKES 323
Query: 689 GYL--NTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
++V S G L +G D +WD+ G +
Sbjct: 324 IIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRV 360
Score = 40.7 bits (91), Expect = 0.006
Identities = 35/138 (25%), Positives = 56/138 (40%), Gaps = 6/138 (4%)
Frame = +2
Query: 398 KTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVR 577
KT R + H VL + + D R+IVS S+D + +W++ K WV
Sbjct: 96 KTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAV-TMPCTWVMACA 154
Query: 578 FSPNHANPIIVSCGWDRTVKVWHLT-----NCKLKINHLG-HSGYLNTVTVSPDGSLCAS 739
++P+ I G D V+ LT N K + H+ YL+ + + +
Sbjct: 155 YAPSGC--AIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILT 212
Query: 740 GGKDMXAMLWDLNDGKHL 793
D LWD+ G+ L
Sbjct: 213 ASGDGTCALWDVESGQLL 230
>AF017656-1|AAC63826.1| 353|Homo sapiens G protein beta 5 subunit
protein.
Length = 353
Score = 75.8 bits (178), Expect = 2e-13
Identities = 54/191 (28%), Positives = 87/191 (45%), Gaps = 2/191 (1%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLW 382
IL++S D T +W + E+ + +G D+ S GN +SG DK +W
Sbjct: 168 ILTASGDGTCALWDV---ESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVW 224
Query: 383 DLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTI-QDDGHSD 559
D+ +G+ + FE H D+ SV + SGS D T +L++ A+ + I +
Sbjct: 225 DMRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIF 284
Query: 560 WVSCVRFSPNHANPIIVSCGW-DRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCA 736
S V FS + ++ G+ D T+ VW + GH ++T+ VSPDG+
Sbjct: 285 GASSVDFS---LSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFC 341
Query: 737 SGGKDMXAMLW 769
SG D +W
Sbjct: 342 SGSWDHTLRVW 352
Score = 64.5 bits (150), Expect = 4e-10
Identities = 59/220 (26%), Positives = 94/220 (42%), Gaps = 3/220 (1%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWK--LTRDENNYGIPQKRLYGH 298
+K R TL+GH V + K I+SSS+D +IVW T E+ +P +
Sbjct: 53 MKTRRTLKGHGNKVLCMDWC-KDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMAC 111
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVS 478
++ S ++ G + T + A K + HT + + +F+ + QI++
Sbjct: 112 AYAPSGCAIACGGLDNKCSVYPLTFDKNENMAAK-KKSVAMHTNYLSACSFTNSDMQILT 170
Query: 479 GSRDKTIKLWNTLAECKYTIQD-DGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 655
S D T LW+ E +Q GH V C+ +P+ VS G D+ VW + +
Sbjct: 171 ASGDGTCALWD--VESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRS 228
Query: 656 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
+ H +N+V P G ASG D L+DL
Sbjct: 229 GQCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDL 268
Score = 58.0 bits (134), Expect = 4e-08
Identities = 55/217 (25%), Positives = 91/217 (41%), Gaps = 6/217 (2%)
Frame = +2
Query: 161 WVTQIATNPKYPDMILSSSRDKTLIVWKLTRDEN-NYGIPQKRLYGHSHFISDVVLSSDG 337
WV A P I D V+ LT D+N N +K + H++++S ++
Sbjct: 107 WVMACAYAPS-GCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSD 165
Query: 338 NYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDV--LSVAFSVDNRQIVSGSRDKTIKLWN 511
L+ S D T LWD+ +G+ + F H DV L +A S VSG DK +W+
Sbjct: 166 MQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWD 225
Query: 512 TLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHS 688
+ +C + H ++ VR+ P + S D T +++ L + + S
Sbjct: 226 MRSGQCVQAFET--HESDINSVRYYP--SGDAFASGSDDATCRLYDLRADREVAIYSKES 281
Query: 689 GYL--NTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
++V S G L +G D +WD+ G +
Sbjct: 282 IIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRV 318
Score = 40.7 bits (91), Expect = 0.006
Identities = 35/138 (25%), Positives = 56/138 (40%), Gaps = 6/138 (4%)
Frame = +2
Query: 398 KTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVR 577
KT R + H VL + + D R+IVS S+D + +W++ K WV
Sbjct: 54 KTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAV-TMPCTWVMACA 112
Query: 578 FSPNHANPIIVSCGWDRTVKVWHLT-----NCKLKINHLG-HSGYLNTVTVSPDGSLCAS 739
++P+ I G D V+ LT N K + H+ YL+ + + +
Sbjct: 113 YAPSGC--AIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILT 170
Query: 740 GGKDMXAMLWDLNDGKHL 793
D LWD+ G+ L
Sbjct: 171 ASGDGTCALWDVESGQLL 188
>AK001642-1|BAA91803.1| 795|Homo sapiens protein ( Homo sapiens
cDNA FLJ10780 fis, clone NT2RP4000376, highly similar to
Homo sapiens mRNA for phospholipase A2 activating
protein. ).
Length = 795
Score = 74.9 bits (176), Expect = 3e-13
Identities = 60/236 (25%), Positives = 106/236 (44%), Gaps = 4/236 (1%)
Frame = +2
Query: 74 RFRESSLFKPFSKMSETLKLRGTLRGHNGWVTQIATNPK---YPD-MILSSSRDKTLIVW 241
R R + L+ P S ++ + GH+ +V+ + P YP +I + D + ++
Sbjct: 39 RDRTTRLWAPDSPNRSFTEMH-CMSGHSNFVSCVCIIPSSDIYPHGLIATGGNDHNICIF 97
Query: 242 KLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFED 421
L +P L GH + + + G LSGSWD T ++W K +
Sbjct: 98 SLDSP-----MPLYILKGHKNTVCSLSSGKFGTL-LSGSWDTTAKVW--LNDKCMMTLQG 149
Query: 422 HTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANP 601
HT V +V + +++GS KT+KLW C+ T GH D CVR +
Sbjct: 150 HTAAVWAVKILPEQGLMLTGSAGKTVKLWKA-GRCERTF--SGHED---CVRGLAILSET 203
Query: 602 IIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
+SC D +++ W +T L++ + GH+ Y+ +++V P+ + +D +W
Sbjct: 204 EFLSCANDASIRRWQITGECLEV-YYGHTNYIYSISVFPNCRDFVTTAEDRSLRIW 258
Score = 54.4 bits (125), Expect = 4e-07
Identities = 55/185 (29%), Positives = 85/185 (45%), Gaps = 7/185 (3%)
Frame = +2
Query: 128 KLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKR-LYGHSH 304
+L +LRGH V + P +S SRD+T +W D N + + GHS+
Sbjct: 9 RLSCSLRGHELDVRGLVCCAYPPGAFVSVSRDRTTRLW--APDSPNRSFTEMHCMSGHSN 66
Query: 305 FISDVVL--SSD----GNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNR 466
F+S V + SSD G A G+ D + ++ L + + H V S++ S
Sbjct: 67 FVSCVCIIPSSDIYPHGLIATGGN-DHNICIFSLDSPMPLYILKGHKNTVCSLS-SGKFG 124
Query: 467 QIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWH 646
++SGS D T K+W +C T+Q GH+ V V+ P + S G +TVK+W
Sbjct: 125 TLLSGSWDTTAKVWLN-DKCMMTLQ--GHTAAVWAVKILPEQGLMLTGSAG--KTVKLWK 179
Query: 647 LTNCK 661
C+
Sbjct: 180 AGRCE 184
>AK131444-1|BAD18589.1| 472|Homo sapiens protein ( Homo sapiens
cDNA FLJ16579 fis, clone TESTI2049956, weakly similar
to Vegetatible incompatibility protein HET-E-1. ).
Length = 472
Score = 74.5 bits (175), Expect = 4e-13
Identities = 51/204 (25%), Positives = 94/204 (46%), Gaps = 10/204 (4%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSG-SWDKTLRL 379
++++S DKT+ W L + + + + FI S DG Y +SG D + +
Sbjct: 160 VIAASYDKTVRAWDLETGKLLWKVR------YDTFIVSCKFSPDGKYVVSGFDVDHGICI 213
Query: 380 WDLAAGKTTRRFEDH-TKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHS 556
D T +DH T+ + S F D++++ S S D+ IK+W+ ++ HS
Sbjct: 214 MDAENITTVSVIKDHHTRSITSCCFDPDSQRVASVSLDRCIKIWDVTSQATLLTITKAHS 273
Query: 557 DWVS--CVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL------GHSGYLNTVTV 712
+ +S C FS + + + WD+ +K+W++ + + GH G +++
Sbjct: 274 NAISNCCFTFSGH----FLCTSSWDKNLKIWNVHTGEFRNRGACVTLMQGHEGSVSSCHF 329
Query: 713 SPDGSLCASGGKDMXAMLWDLNDG 784
+ D S SGG D +WD+ +G
Sbjct: 330 ARDSSFLISGGFDRTVAIWDVAEG 353
Score = 71.7 bits (168), Expect = 3e-12
Identities = 34/104 (32%), Positives = 59/104 (56%), Gaps = 1/104 (0%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKL-TRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRL 379
+ +SS DK L +W + T + N G + GH +S + D ++ +SG +D+T+ +
Sbjct: 288 LCTSSWDKNLKIWNVHTGEFRNRGACVTLMQGHEGSVSSCHFARDSSFLISGGFDRTVAI 347
Query: 380 WDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN 511
WD+A G + H V+ VA S + + I+S S+D+T++LWN
Sbjct: 348 WDVAEGYRKLSLKGHNDWVMDVAISNNKKWILSASKDRTMRLWN 391
Score = 66.9 bits (156), Expect = 8e-11
Identities = 48/170 (28%), Positives = 78/170 (45%), Gaps = 2/170 (1%)
Frame = +2
Query: 272 IPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTK-DVLSVA 448
IP K L GH H +S D LSGS+D T++LWD G R FE K V+ +
Sbjct: 93 IPFKILSGHEHAVSTCHFCVDDTKLLSGSYDCTVKLWDPVDGSVVRDFEHRPKAPVVECS 152
Query: 449 FSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR 628
+ D+ ++++ S DKT++ W+ L K + + VSC +FSP+ ++ D
Sbjct: 153 ITGDSSRVIAASYDKTVRAWD-LETGKLLWKVRYDTFIVSC-KFSPD-GKYVVSGFDVDH 209
Query: 629 TVKVWHLTN-CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
+ + N + + H+ + + PD AS D +WD+
Sbjct: 210 GICIMDAENITTVSVIKDHHTRSITSCCFDPDSQRVASVSLDRCIKIWDV 259
Score = 66.9 bits (156), Expect = 8e-11
Identities = 41/170 (24%), Positives = 77/170 (45%), Gaps = 8/170 (4%)
Frame = +2
Query: 296 HSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRF-EDHTKDVLSVAFSVDNRQI 472
H+ I+ D S S D+ +++WD+ + T + H+ + + F+ +
Sbjct: 229 HTRSITSCCFDPDSQRVASVSLDRCIKIWDVTSQATLLTITKAHSNAISNCCFTFSGHFL 288
Query: 473 VSGSRDKTIKLWNT-------LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRT 631
+ S DK +K+WN C +Q GH VS F+ + + ++S G+DRT
Sbjct: 289 CTSSWDKNLKIWNVHTGEFRNRGACVTLMQ--GHEGSVSSCHFARDSS--FLISGGFDRT 344
Query: 632 VKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLND 781
V +W + K++ GH+ ++ V +S + S KD LW++ +
Sbjct: 345 VAIWDVAEGYRKLSLKGHNDWVMDVAISNNKKWILSASKDRTMRLWNIEE 394
Score = 45.6 bits (103), Expect = 2e-04
Identities = 23/82 (28%), Positives = 45/82 (54%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
++GH G V+ + ++S D+T+ +W + G + L GH+ ++ DV
Sbjct: 317 MQGHEGSVSSCHF-ARDSSFLISGGFDRTVAIWDVAE-----GYRKLSLKGHNDWVMDVA 370
Query: 323 LSSDGNYALSGSWDKTLRLWDL 388
+S++ + LS S D+T+RLW++
Sbjct: 371 ISNNKKWILSASKDRTMRLWNI 392
Score = 35.9 bits (79), Expect = 0.17
Identities = 19/53 (35%), Positives = 30/53 (56%), Gaps = 1/53 (1%)
Frame = +2
Query: 140 TLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTR-DENNYGIPQKRLYG 295
+L+GHN WV +A + ILS+S+D+T+ +W + DE I K+ G
Sbjct: 358 SLKGHNDWVMDVAIS-NNKKWILSASKDRTMRLWNIEEIDEIPLVIKYKKAVG 409
>AK074217-1|BAB85020.1| 506|Homo sapiens protein ( Homo sapiens
cDNA FLJ23637 fis, clone CAS09287. ).
Length = 506
Score = 74.1 bits (174), Expect = 5e-13
Identities = 47/155 (30%), Positives = 79/155 (50%), Gaps = 1/155 (0%)
Frame = +2
Query: 332 DGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWN 511
DG ++GS D ++L+D++ R+FE HTK V +V + D +VSG+ D T+KLW+
Sbjct: 91 DGRLLVAGSEDGGVQLFDISGRAPLRQFEGHTKAVHTVDSTADKYHVVSGADDYTVKLWD 150
Query: 512 TLAECKYTIQDDGHSDWVSCVRFSPNHANP-IIVSCGWDRTVKVWHLTNCKLKINHLGHS 688
+ K + HSD+V C + NP + ++ +D TVK++ + + + H
Sbjct: 151 -IPNSKEILTFKEHSDYVRC--GCASKLNPDLFITGSYDHTVKMFDARTSE-SVLSVEHG 206
Query: 689 GYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ +V + P G L S G +WD+ G L
Sbjct: 207 QPVESVLLFPSGGLLVSAG-GRYVKVWDMLKGGQL 240
Score = 60.1 bits (139), Expect = 9e-09
Identities = 45/176 (25%), Positives = 82/176 (46%), Gaps = 2/176 (1%)
Frame = +2
Query: 275 PQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDV-LSVAF 451
P ++ GH+ + V ++D + +SG+ D T++LWD+ K F++H+ V A
Sbjct: 114 PLRQFEGHTKAVHTVDSTADKYHVVSGADDYTVKLWDIPNSKEILTFKEHSDYVRCGCAS 173
Query: 452 SVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRT 631
++ ++GS D T+K+++ A ++ H V V P + ++VS G R
Sbjct: 174 KLNPDLFITGSYDHTVKMFD--ARTSESVLSVEHGQPVESVLLFP--SGGLLVSAG-GRY 228
Query: 632 VKVWH-LTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHLH 796
VKVW L +L ++ H + + +S G SG D ++ K +H
Sbjct: 229 VKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVH 284
Score = 39.1 bits (87), Expect = 0.018
Identities = 22/81 (27%), Positives = 42/81 (51%)
Frame = +2
Query: 287 LYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNR 466
L H ++ + LSS G LSGS D+ ++++ + K F D+ +LS+A + ++
Sbjct: 244 LKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSF-DYAASILSLALAHEDE 302
Query: 467 QIVSGSRDKTIKLWNTLAECK 529
IV G + + + + +E K
Sbjct: 303 TIVVGMTNGILSVKHRKSEAK 323
>AK222576-1|BAD96296.1| 421|Homo sapiens WD SOCS-box protein 1
isoform 1 variant protein.
Length = 421
Score = 73.7 bits (173), Expect = 7e-13
Identities = 41/139 (29%), Positives = 69/139 (49%), Gaps = 1/139 (0%)
Frame = +2
Query: 371 LRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI-VSGSRDKTIKLWNTLAECKYTIQDD 547
+++WD+ GK DHT+ V + F+ D I VS SRDKT+++W+ +
Sbjct: 152 IKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKVLR 211
Query: 548 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 727
GH +WV FSP+ + ++ S G + V +W++ + G + SPDG+
Sbjct: 212 GHQNWVYSCAFSPD--SSMLCSVGASKAVFLWNMDKYTMIRKLEGRHHDVVACDFSPDGA 269
Query: 728 LCASGGKDMXAMLWDLNDG 784
L A+ D +WD ++G
Sbjct: 270 LLATASYDTRVYIWDPHNG 288
Score = 64.5 bits (150), Expect = 4e-10
Identities = 63/229 (27%), Positives = 98/229 (42%), Gaps = 13/229 (5%)
Frame = +2
Query: 122 TLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHS 301
T KL L H V + P +++S+SRDKTL VW L +D+ N K L GH
Sbjct: 159 TGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDL-KDDGNM---MKVLRGHQ 214
Query: 302 HFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSG 481
+++ S D + S K + LW++ R+ E DV++ FS D + +
Sbjct: 215 NWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEGRHHDVVACDFSPDGALLATA 274
Query: 482 SRDKTIKLW-----NTLAECKY------TIQDDGHSD-WVSCVRFSPNHANPIIVSCGWD 625
S D + +W + L E + I G +D WV V FS H + S D
Sbjct: 275 SYDTRVYIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSFS--HDGLHVASLADD 332
Query: 626 RTVKVWHL-TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
+ V+ W + + +++ L + S DGS+ A+G D W
Sbjct: 333 KMVRFWRIDEDYPVQVAPLSNG---LCCAFSTDGSVLAAGTHDGSVYFW 378
>BC015887-1|AAH15887.1| 404|Homo sapiens WD repeat and SOCS
box-containing 2 protein.
Length = 404
Score = 72.9 bits (171), Expect = 1e-12
Identities = 60/220 (27%), Positives = 98/220 (44%), Gaps = 11/220 (5%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH V ++ P +++S+SRDKTL +W L N +G + L GH ++
Sbjct: 149 LSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDL----NKHGKQIQVLSGHLQWVYCCS 204
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
+S D + S + +K++ LW + + R+ E H V+S FS D+ +V+ S D +
Sbjct: 205 ISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCDFSPDSALLVTASYDTNVI 264
Query: 503 LWN-----TLAECKYTIQD------DGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 649
+W+ L +T D D H + V FSP + + DR +++W L
Sbjct: 265 MWDPYTGERLRSLHHTQVDPAMDDSDVHISSLRSVCFSPE--GLYLATVADDRLLRIWAL 322
Query: 650 TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
K I + L T P G + A+G +D W
Sbjct: 323 -ELKTPIAFAPMTNGL-CCTFFPHGGVIATGTRDGHVQFW 360
Score = 68.1 bits (159), Expect = 3e-11
Identities = 39/149 (26%), Positives = 69/149 (46%), Gaps = 1/149 (0%)
Frame = +2
Query: 350 SGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI-VSGSRDKTIKLWNTLAEC 526
+G D +++W++ G H V ++F+ I VS SRDKT+++W+
Sbjct: 128 TGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNKHG 187
Query: 527 KYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTV 706
K GH WV C SP+ + ++ S +++V +W + + L GH + +
Sbjct: 188 KQIQVLSGHLQWVYCCSISPDCS--MLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSC 245
Query: 707 TVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
SPD +L + D ++WD G+ L
Sbjct: 246 DFSPDSALLVTASYDTNVIMWDPYTGERL 274
Score = 61.7 bits (143), Expect = 3e-09
Identities = 59/218 (27%), Positives = 102/218 (46%), Gaps = 20/218 (9%)
Frame = +2
Query: 182 NPKYPD---MILSSS-RDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYAL 349
+P+ PD ++L++ D + +W++ G+ L GH + D+ + G+ L
Sbjct: 115 HPQVPDVSCLVLATGLNDGQIKIWEVQT-----GLLLLNLSGHQDVVRDLSFTPSGSLIL 169
Query: 350 -SGSWDKTLRLWDLAA-GKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAE 523
S S DKTLR+WDL GK + H + V + S D + S + +K++ LW+ +
Sbjct: 170 VSASRDKTLRIWDLNKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRS- 228
Query: 524 CKYTI--QDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWH-LTNCKLK-INHLG--- 682
YT+ + +GH V FSP+ A ++V+ +D V +W T +L+ ++H
Sbjct: 229 --YTLIRKLEGHQSSVVSCDFSPDSA--LLVTASYDTNVIMWDPYTGERLRSLHHTQVDP 284
Query: 683 -------HSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
H L +V SP+G A+ D +W L
Sbjct: 285 AMDDSDVHISSLRSVCFSPEGLYLATVADDRLLRIWAL 322
>AF229181-1|AAF71302.1| 404|Homo sapiens CS box-containing WD
protein protein.
Length = 404
Score = 72.9 bits (171), Expect = 1e-12
Identities = 60/220 (27%), Positives = 98/220 (44%), Gaps = 11/220 (5%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH V ++ P +++S+SRDKTL +W L N +G + L GH ++
Sbjct: 149 LSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDL----NKHGKQIQVLSGHLQWVYCCS 204
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
+S D + S + +K++ LW + + R+ E H V+S FS D+ +V+ S D +
Sbjct: 205 ISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCDFSPDSALLVTASYDTNVI 264
Query: 503 LWN-----TLAECKYTIQD------DGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 649
+W+ L +T D D H + V FSP + + DR +++W L
Sbjct: 265 MWDPYTGERLRSLHHTQVDPAMDDSDVHISSLRSVCFSPE--GLYLATVADDRLLRIWAL 322
Query: 650 TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
K I + L T P G + A+G +D W
Sbjct: 323 -ELKTPIAFAPMTNGL-CCTFFPHGGVIATGTRDGHVQFW 360
Score = 68.1 bits (159), Expect = 3e-11
Identities = 39/149 (26%), Positives = 69/149 (46%), Gaps = 1/149 (0%)
Frame = +2
Query: 350 SGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI-VSGSRDKTIKLWNTLAEC 526
+G D +++W++ G H V ++F+ I VS SRDKT+++W+
Sbjct: 128 TGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNKHG 187
Query: 527 KYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTV 706
K GH WV C SP+ + ++ S +++V +W + + L GH + +
Sbjct: 188 KQIQVLSGHLQWVYCCSISPDCS--MLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSC 245
Query: 707 TVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
SPD +L + D ++WD G+ L
Sbjct: 246 DFSPDSALLVTASYDTNVIMWDPYTGERL 274
Score = 61.7 bits (143), Expect = 3e-09
Identities = 59/218 (27%), Positives = 102/218 (46%), Gaps = 20/218 (9%)
Frame = +2
Query: 182 NPKYPD---MILSSS-RDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYAL 349
+P+ PD ++L++ D + +W++ G+ L GH + D+ + G+ L
Sbjct: 115 HPQVPDVSCLVLATGLNDGQIKIWEVQT-----GLLLLNLSGHQDVVRDLSFTPSGSLIL 169
Query: 350 -SGSWDKTLRLWDLAA-GKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAE 523
S S DKTLR+WDL GK + H + V + S D + S + +K++ LW+ +
Sbjct: 170 VSASRDKTLRIWDLNKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRS- 228
Query: 524 CKYTI--QDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWH-LTNCKLK-INHLG--- 682
YT+ + +GH V FSP+ A ++V+ +D V +W T +L+ ++H
Sbjct: 229 --YTLIRKLEGHQSSVVSCDFSPDSA--LLVTASYDTNVIMWDPYTGERLRSLHHTQVDP 284
Query: 683 -------HSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
H L +V SP+G A+ D +W L
Sbjct: 285 AMDDSDVHISSLRSVCFSPEGLYLATVADDRLLRIWAL 322
>AF163324-1|AAF80478.1| 404|Homo sapiens WSB-2 protein.
Length = 404
Score = 72.9 bits (171), Expect = 1e-12
Identities = 60/220 (27%), Positives = 98/220 (44%), Gaps = 11/220 (5%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH V ++ P +++S+SRDKTL +W L N +G + L GH ++
Sbjct: 149 LSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDL----NKHGKQIQVLSGHLQWVYCCS 204
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
+S D + S + +K++ LW + + R+ E H V+S FS D+ +V+ S D +
Sbjct: 205 ISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCDFSPDSALLVTASYDTNVI 264
Query: 503 LWN-----TLAECKYTIQD------DGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 649
+W+ L +T D D H + V FSP + + DR +++W L
Sbjct: 265 MWDPYTGERLRSLHHTQVDPAMDDSDVHISSLRSVCFSPE--GLYLATVADDRLLRIWAL 322
Query: 650 TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
K I + L T P G + A+G +D W
Sbjct: 323 -ELKTPIAFAPMTNGL-CCTFFPHGGVIATGTRDGHVQFW 360
Score = 68.1 bits (159), Expect = 3e-11
Identities = 39/149 (26%), Positives = 69/149 (46%), Gaps = 1/149 (0%)
Frame = +2
Query: 350 SGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI-VSGSRDKTIKLWNTLAEC 526
+G D +++W++ G H V ++F+ I VS SRDKT+++W+
Sbjct: 128 TGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNKHG 187
Query: 527 KYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTV 706
K GH WV C SP+ + ++ S +++V +W + + L GH + +
Sbjct: 188 KQIQVLSGHLQWVYCCSISPDCS--MLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSC 245
Query: 707 TVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
SPD +L + D ++WD G+ L
Sbjct: 246 DFSPDSALLVTASYDTNVIMWDPYTGERL 274
Score = 61.7 bits (143), Expect = 3e-09
Identities = 59/218 (27%), Positives = 102/218 (46%), Gaps = 20/218 (9%)
Frame = +2
Query: 182 NPKYPD---MILSSS-RDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYAL 349
+P+ PD ++L++ D + +W++ G+ L GH + D+ + G+ L
Sbjct: 115 HPQVPDVSCLVLATGLNDGQIKIWEVQT-----GLLLLNLSGHQDVVRDLSFTPSGSLIL 169
Query: 350 -SGSWDKTLRLWDLAA-GKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAE 523
S S DKTLR+WDL GK + H + V + S D + S + +K++ LW+ +
Sbjct: 170 VSASRDKTLRIWDLNKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRS- 228
Query: 524 CKYTI--QDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWH-LTNCKLK-INHLG--- 682
YT+ + +GH V FSP+ A ++V+ +D V +W T +L+ ++H
Sbjct: 229 --YTLIRKLEGHQSSVVSCDFSPDSA--LLVTASYDTNVIMWDPYTGERLRSLHHTQVDP 284
Query: 683 -------HSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
H L +V SP+G A+ D +W L
Sbjct: 285 AMDDSDVHISSLRSVCFSPEGLYLATVADDRLLRIWAL 322
>AF106683-1|AAD43036.1| 421|Homo sapiens WSB-1 protein.
Length = 421
Score = 72.5 bits (170), Expect = 2e-12
Identities = 40/139 (28%), Positives = 68/139 (48%), Gaps = 1/139 (0%)
Frame = +2
Query: 371 LRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI-VSGSRDKTIKLWNTLAECKYTIQDD 547
+++WD+ GK DHT+ V + + D I VS SRDKT+++W+ +
Sbjct: 152 IKIWDVYTGKLLLNLVDHTEVVRDLTLAPDGSLILVSASRDKTLRVWDLKDDGNMMKVLR 211
Query: 548 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 727
GH +WV FSP+ + ++ G + V +W++ + GH + SPDG+
Sbjct: 212 GHQNWVYSCAFSPDSS--MLCPVGASKAVFLWNMDKYTMIRKLEGHHHDVVACDFSPDGA 269
Query: 728 LCASGGKDMXAMLWDLNDG 784
L A+ D +WD ++G
Sbjct: 270 LLATASYDTRVYIWDPHNG 288
Score = 66.1 bits (154), Expect = 1e-10
Identities = 63/229 (27%), Positives = 98/229 (42%), Gaps = 13/229 (5%)
Frame = +2
Query: 122 TLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHS 301
T KL L H V + P +++S+SRDKTL VW L +D+ N K L GH
Sbjct: 159 TGKLLLNLVDHTEVVRDLTLAPDGSLILVSASRDKTLRVWDL-KDDGNM---MKVLRGHQ 214
Query: 302 HFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSG 481
+++ S D + K + LW++ R+ E H DV++ FS D + +
Sbjct: 215 NWVYSCAFSPDSSMLCPVGASKAVFLWNMDKYTMIRKLEGHHHDVVACDFSPDGALLATA 274
Query: 482 SRDKTIKLW-----NTLAECKY------TIQDDGHSD-WVSCVRFSPNHANPIIVSCGWD 625
S D + +W + L E + I G +D WV V FS H + S D
Sbjct: 275 SYDTRVYIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSFS--HDGLHVASLADD 332
Query: 626 RTVKVWHL-TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLW 769
+ V+ W + + +++ L + S DGS+ A+G D W
Sbjct: 333 KMVRFWRIDEDYPVQVAPLSNG---LCCAFSTDGSVLAAGTHDGSVYFW 378
>AF070603-1|AAC28655.1| 207|Homo sapiens beta-subunit signal
transducing proteins GS/GI protein.
Length = 207
Score = 71.7 bits (168), Expect = 3e-12
Identities = 49/167 (29%), Positives = 79/167 (47%), Gaps = 3/167 (1%)
Frame = +2
Query: 281 KRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVD 460
+ L GH+ ++S D N ++ S D T LWD+ G+ T F HT DV+S++ + D
Sbjct: 4 RELAGHTGYLSCCRFLDD-NQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPD 62
Query: 461 NRQIVSGSRDKTIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVK 637
R VSG+ D + KLW+ C+ T GH ++ + F PN N D T +
Sbjct: 63 TRLFVSGACDASAKLWDVREGMCRQTF--TGHESDINAICFFPN-GNAFATGSD-DATCR 118
Query: 638 VWHLTNCK--LKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
++ L + + +H + +V+ S G L +G D +WD
Sbjct: 119 LFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWD 165
Score = 64.9 bits (151), Expect = 3e-10
Identities = 49/212 (23%), Positives = 91/212 (42%), Gaps = 2/212 (0%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVV 322
L GH G+++ + I++SS D T +W + + GH+ + +
Sbjct: 6 LAGHTGYLS--CCRFLDDNQIVTSSGDTTCALWDIETGQQT-----TTFTGHTGDVMSLS 58
Query: 323 LSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIK 502
L+ D +SG+ D + +LWD+ G + F H D+ ++ F + +GS D T +
Sbjct: 59 LAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCR 118
Query: 503 LWNTLAECKY-TIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR-TVKVWHLTNCKLKINH 676
L++ A+ + T D ++ V FS + ++ G+D VW
Sbjct: 119 LFDLRADQELMTYSHDNIICGITSVSFSKSGR---LLLAGYDDFNCNVWDALKADRAGVL 175
Query: 677 LGHSGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
GH ++ + V+ DG A+G D +W+
Sbjct: 176 AGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 207
Score = 58.8 bits (136), Expect = 2e-08
Identities = 45/178 (25%), Positives = 83/178 (46%), Gaps = 2/178 (1%)
Frame = +2
Query: 119 ETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGH 298
ET + T GH G V ++ P + +S + D + +W + G+ ++ GH
Sbjct: 39 ETGQQTTTFTGHTGDVMSLSLAPD-TRLFVSGACDASAKLWDVRE-----GMCRQTFTGH 92
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGK--TTRRFEDHTKDVLSVAFSVDNRQI 472
I+ + +GN +GS D T RL+DL A + T ++ + SV+FS R +
Sbjct: 93 ESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLL 152
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWH 646
++G D +W+ L + + GH + VSC+ + + + + WD +K+W+
Sbjct: 153 LAGYDDFNCNVWDALKADRAGVL-AGHDNRVSCLGVTDD--GMAVATGSWDSFLKIWN 207
Score = 55.2 bits (127), Expect = 3e-07
Identities = 36/132 (27%), Positives = 60/132 (45%)
Frame = +2
Query: 398 KTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVR 577
+ +R HT LS +D+ QIV+ S D T LW+ + + T GH+ V +
Sbjct: 1 RVSRELAGHT-GYLSCCRFLDDNQIVTSSGDTTCALWD-IETGQQTTTFTGHTGDVMSLS 58
Query: 578 FSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMX 757
+P+ + VS D + K+W + + GH +N + P+G+ A+G D
Sbjct: 59 LAPD--TRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDAT 116
Query: 758 AMLWDLNDGKHL 793
L+DL + L
Sbjct: 117 CRLFDLRADQEL 128
>BC028364-1|AAH28364.1| 1061|Homo sapiens FBXW10 protein protein.
Length = 1061
Score = 70.9 bits (166), Expect = 5e-12
Identities = 48/162 (29%), Positives = 75/162 (46%), Gaps = 1/162 (0%)
Frame = +2
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI 472
GH+ + + L + N+ LSGS+D ++R WDL +G TR F H + + ++
Sbjct: 480 GHAGSVRALFLCEEENFLLSGSYDLSIRYWDLKSGVCTRIFGGHQGTI--TCMDLCKNRL 537
Query: 473 VSGSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 649
VSG RD +K+W+ +C T + H D + R + + I+ SC VKVWH+
Sbjct: 538 VSGGRDCQVKVWDVDTGKCLKTFR---HKDPILATRINDTY---IVSSCE-RGLVKVWHI 590
Query: 650 TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
+L GH G + + D SG D M W +
Sbjct: 591 AMAQLVKTLSGHEGAVKCLFF--DQWHLLSGSTDGLVMAWSM 630
Score = 35.9 bits (79), Expect = 0.17
Identities = 30/115 (26%), Positives = 50/115 (43%), Gaps = 1/115 (0%)
Frame = +2
Query: 320 VLSSDGNYALSGSWDKTLRLWDLAAGKTTR-RFEDHTKDVLSVAFSVDNRQIVSGSRDKT 496
V+ G ++ S ++ + L D+ K F H V ++ + ++SGS D +
Sbjct: 446 VIHYSGGDLIAVSSNRKIHLLDIIQVKAIPVEFRGHAGSVRALFLCEEENFLLSGSYDLS 505
Query: 497 IKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 661
I+ W+ L T GH ++C+ N +VS G D VKVW + K
Sbjct: 506 IRYWD-LKSGVCTRIFGGHQGTITCMDLCKNR----LVSGGRDCQVKVWDVDTGK 555
Score = 32.7 bits (71), Expect = 1.6
Identities = 24/108 (22%), Positives = 51/108 (47%)
Frame = +2
Query: 470 IVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 649
+++ S ++ I L + + ++ GH+ V + F N ++S +D +++ W L
Sbjct: 454 LIAVSSNRKIHLLDIIQVKAIPVEFRGHAGSVRAL-FLCEEEN-FLLSGSYDLSIRYWDL 511
Query: 650 TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ GH G + + + + + SGG+D +WD++ GK L
Sbjct: 512 KSGVCTRIFGGHQGTITCMDLCKNRLV--SGGRDCQVKVWDVDTGKCL 557
>AY729024-1|AAU43731.1| 1052|Homo sapiens ubiquitin ligase
specificity factor protein.
Length = 1052
Score = 70.9 bits (166), Expect = 5e-12
Identities = 48/162 (29%), Positives = 75/162 (46%), Gaps = 1/162 (0%)
Frame = +2
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI 472
GH+ + + L + N+ LSGS+D ++R WDL +G TR F H + + ++
Sbjct: 451 GHAGSVRALFLCEEENFLLSGSYDLSIRYWDLKSGVCTRIFGGHQGTI--TCMDLCKNRL 508
Query: 473 VSGSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 649
VSG RD +K+W+ +C T + H D + R + + I+ SC VKVWH+
Sbjct: 509 VSGGRDCQVKVWDVDTGKCLKTFR---HKDPILATRINDTY---IVSSCE-RGLVKVWHI 561
Query: 650 TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
+L GH G + + D SG D M W +
Sbjct: 562 AMAQLVKTLSGHEGAVKCLFF--DQWHLLSGSTDGLVMAWSM 601
Score = 35.9 bits (79), Expect = 0.17
Identities = 30/115 (26%), Positives = 50/115 (43%), Gaps = 1/115 (0%)
Frame = +2
Query: 320 VLSSDGNYALSGSWDKTLRLWDLAAGKTTR-RFEDHTKDVLSVAFSVDNRQIVSGSRDKT 496
V+ G ++ S ++ + L D+ K F H V ++ + ++SGS D +
Sbjct: 417 VIHYSGGDLIAVSSNRKIHLLDIIQVKAIPVEFRGHAGSVRALFLCEEENFLLSGSYDLS 476
Query: 497 IKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 661
I+ W+ L T GH ++C+ N +VS G D VKVW + K
Sbjct: 477 IRYWD-LKSGVCTRIFGGHQGTITCMDLCKNR----LVSGGRDCQVKVWDVDTGK 526
Score = 32.7 bits (71), Expect = 1.6
Identities = 24/108 (22%), Positives = 51/108 (47%)
Frame = +2
Query: 470 IVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 649
+++ S ++ I L + + ++ GH+ V + F N ++S +D +++ W L
Sbjct: 425 LIAVSSNRKIHLLDIIQVKAIPVEFRGHAGSVRAL-FLCEEEN-FLLSGSYDLSIRYWDL 482
Query: 650 TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ GH G + + + + + SGG+D +WD++ GK L
Sbjct: 483 KSGVCTRIFGGHQGTITCMDLCKNRLV--SGGRDCQVKVWDVDTGKCL 528
>AB209899-1|BAD93136.1| 967|Homo sapiens Hypothetical protein
DKFZp434O1826 variant protein.
Length = 967
Score = 70.9 bits (166), Expect = 5e-12
Identities = 48/162 (29%), Positives = 75/162 (46%), Gaps = 1/162 (0%)
Frame = +2
Query: 293 GHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQI 472
GH+ + + L + N+ LSGS+D ++R WDL +G TR F H + + ++
Sbjct: 775 GHAGSVRALFLCEEENFLLSGSYDLSIRYWDLKSGVCTRIFGGHQGTI--TCMDLCKNRL 832
Query: 473 VSGSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 649
VSG RD +K+W+ +C T + H D + R + + I+ SC VKVWH+
Sbjct: 833 VSGGRDCQVKVWDVDTGKCLKTFR---HKDPILATRINDTY---IVSSCE-RGLVKVWHI 885
Query: 650 TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDL 775
+L GH G + + D SG D M W +
Sbjct: 886 AMAQLVKTLSGHEGAVKCLFF--DQWHLLSGSTDGLVMAWSM 925
Score = 35.9 bits (79), Expect = 0.17
Identities = 30/115 (26%), Positives = 50/115 (43%), Gaps = 1/115 (0%)
Frame = +2
Query: 320 VLSSDGNYALSGSWDKTLRLWDLAAGKTTR-RFEDHTKDVLSVAFSVDNRQIVSGSRDKT 496
V+ G ++ S ++ + L D+ K F H V ++ + ++SGS D +
Sbjct: 741 VIHYSGGDLIAVSSNRKIHLLDIIQVKAIPVEFRGHAGSVRALFLCEEENFLLSGSYDLS 800
Query: 497 IKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 661
I+ W+ L T GH ++C+ N +VS G D VKVW + K
Sbjct: 801 IRYWD-LKSGVCTRIFGGHQGTITCMDLCKNR----LVSGGRDCQVKVWDVDTGK 850
Score = 32.7 bits (71), Expect = 1.6
Identities = 24/108 (22%), Positives = 51/108 (47%)
Frame = +2
Query: 470 IVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 649
+++ S ++ I L + + ++ GH+ V + F N ++S +D +++ W L
Sbjct: 749 LIAVSSNRKIHLLDIIQVKAIPVEFRGHAGSVRAL-FLCEEEN-FLLSGSYDLSIRYWDL 806
Query: 650 TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ GH G + + + + + SGG+D +WD++ GK L
Sbjct: 807 KSGVCTRIFGGHQGTITCMDLCKNRLV--SGGRDCQVKVWDVDTGKCL 852
>Y12050-1|CAA72779.1| 340|Homo sapiens guanine nucleotide-binding
protein beta3 subunit protein.
Length = 340
Score = 70.5 bits (165), Expect = 6e-12
Identities = 58/229 (25%), Positives = 100/229 (43%), Gaps = 6/229 (2%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQI--ATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGH 298
++ R TLRGH + + AT+ K +++S+S+D LIVW + IP +
Sbjct: 45 MRTRRTLRGHLAKIYAMHWATDSK---LLVSASQDGKLIVWDSYTTNKVHAIPLR----- 96
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAG----KTTRRFEDHTKDVLSVAFSVDNR 466
S ++ + GN+ G D +++L + K +R HT LS +D+
Sbjct: 97 SSWVMTCAYAPSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHT-GYLSCCRFLDDN 155
Query: 467 QIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWH 646
IV+ S D T LW+ + T+ GH+ + SP+ + +S D + K+W
Sbjct: 156 NIVTSSGDTTCALWDIETGQQKTVFV-GHTGDCMSLAVSPDFN--LFISGACDASAKLWD 212
Query: 647 LTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ + GH +N + P+G +G D L+DL + L
Sbjct: 213 VREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQEL 261
Score = 66.5 bits (155), Expect = 1e-10
Identities = 54/209 (25%), Positives = 88/209 (42%), Gaps = 3/209 (1%)
Frame = +2
Query: 155 NGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSD 334
+ WV A P + + D ++ L E N + + L H+ ++S D
Sbjct: 97 SSWVMTCAYAPS-GNFVACGGLDNMCSIYNLKSREGNVKV-SRELSAHTGYLSCCRFLDD 154
Query: 335 GNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNT 514
N S S D T LWD+ G+ F HT D +S+A S D +SG+ D + KLW+
Sbjct: 155 NNIVTS-SGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDV 213
Query: 515 L-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK--LKINHLGH 685
C+ T GH ++ + F PN I + D + +++ L + + +H
Sbjct: 214 REGTCRQTF--TGHESDINAICFFPN--GEAICTGSDDASCRLFDLRADQELICFSHESI 269
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ +V S G L +G D +WD
Sbjct: 270 ICGITSVAFSLSGRLLFAGYDDFNCNVWD 298
Score = 60.9 bits (141), Expect = 5e-09
Identities = 46/193 (23%), Positives = 88/193 (45%), Gaps = 3/193 (1%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLY-GHSHFISDVVLSSDGNYALSGSWDKTLRL 379
I++SS D T +W + + QK ++ GH+ + +S D N +SG+ D + +L
Sbjct: 157 IVTSSGDTTCALWDIETGQ------QKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKL 210
Query: 380 WDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYT-IQDDGHS 556
WD+ G + F H D+ ++ F + I +GS D + +L++ A+ + +
Sbjct: 211 WDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESII 270
Query: 557 DWVSCVRFSPNHANPIIVSCGWDR-TVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLC 733
++ V FS + ++ G+D VW + GH ++ + V+ DG
Sbjct: 271 CGITSVAFSLSGR---LLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAV 327
Query: 734 ASGGKDMXAMLWD 772
A+G D +W+
Sbjct: 328 ATGSWDSFLKIWN 340
Score = 60.5 bits (140), Expect = 7e-09
Identities = 47/179 (26%), Positives = 86/179 (48%), Gaps = 3/179 (1%)
Frame = +2
Query: 119 ETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGH 298
ET + + GH G +A +P + ++ +S + D + +W + G ++ GH
Sbjct: 172 ETGQQKTVFVGHTGDCMSLAVSPDF-NLFISGACDASAKLWDVRE-----GTCRQTFTGH 225
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRF--EDHTKDVLSVAFSVDNRQI 472
I+ + +G +GS D + RL+DL A + F E + SVAFS+ R +
Sbjct: 226 ESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRLL 285
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCG-WDRTVKVWH 646
+G D +W+++ + I GH + VSC+ + A+ + V+ G WD +K+W+
Sbjct: 286 FAGYDDFNCNVWDSMKSERVGIL-SGHDNRVSCLGVT---ADGMAVATGSWDSFLKIWN 340
>X74262-1|CAA52321.1| 425|Homo sapiens retinoblastoma binding
protein protein.
Length = 425
Score = 70.5 bits (165), Expect = 6e-12
Identities = 66/250 (26%), Positives = 118/250 (47%), Gaps = 18/250 (7%)
Frame = +2
Query: 83 ESSLFKPFSKMSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTR--- 253
E F F +S +++ + H G V + P+ P +I + + ++V+ T+
Sbjct: 101 EKGEFGGFGSVSGKIEIEIKIN-HEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPS 159
Query: 254 --DENNYGIPQKRLYGHSHFISDVVLSSD-GNYALSGSWDKTLRLWDLAA----GKTTRR 412
D + P RL GH + + + + LS S D T+ LWD++A GK
Sbjct: 160 KPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDA 219
Query: 413 ---FEDHTKDVLSVAFSVDNRQIV-SGSRDKTIKLWNTLAE--CKYTIQDDGHSDWVSCV 574
F HT V V++ + + + S + D+ + +W+T + K + D H+ V+C+
Sbjct: 220 KTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCL 279
Query: 575 RFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL-GHSGYLNTVTVSP-DGSLCASGGK 748
F+P ++ I+ + D+TV +W L N KLK++ H + V SP + ++ AS G
Sbjct: 280 SFNP-YSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGT 338
Query: 749 DMXAMLWDLN 778
D +WDL+
Sbjct: 339 DRRLNVWDLS 348
>X71810-1|CAA50685.1| 410|Homo sapiens IEF SSP 9306 protein.
Length = 410
Score = 70.5 bits (165), Expect = 6e-12
Identities = 66/250 (26%), Positives = 118/250 (47%), Gaps = 18/250 (7%)
Frame = +2
Query: 83 ESSLFKPFSKMSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTR--- 253
E F F +S +++ + H G V + P+ P +I + + ++V+ T+
Sbjct: 101 EKGEFGGFGSVSGKIEIEIKIN-HEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPS 159
Query: 254 --DENNYGIPQKRLYGHSHFISDVVLSSD-GNYALSGSWDKTLRLWDLAA----GKTTRR 412
D + P RL GH + + + + LS S D T+ LWD++A GK
Sbjct: 160 KPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDA 219
Query: 413 ---FEDHTKDVLSVAFSVDNRQIV-SGSRDKTIKLWNTLAE--CKYTIQDDGHSDWVSCV 574
F HT V V++ + + + S + D+ + +W+T + K + D H+ V+C+
Sbjct: 220 KTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCL 279
Query: 575 RFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL-GHSGYLNTVTVSP-DGSLCASGGK 748
F+P ++ I+ + D+TV +W L N KLK++ H + V SP + ++ AS G
Sbjct: 280 SFNP-YSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGT 338
Query: 749 DMXAMLWDLN 778
D +WDL+
Sbjct: 339 DRRLNVWDLS 348
>U47924-5|AAB51313.1| 340|Homo sapiens G-protein beta-3 chain
protein.
Length = 340
Score = 70.5 bits (165), Expect = 6e-12
Identities = 58/229 (25%), Positives = 100/229 (43%), Gaps = 6/229 (2%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQI--ATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGH 298
++ R TLRGH + + AT+ K +++S+S+D LIVW + IP +
Sbjct: 45 MRTRRTLRGHLAKIYAMHWATDSK---LLVSASQDGKLIVWDSYTTNKVHAIPLR----- 96
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAG----KTTRRFEDHTKDVLSVAFSVDNR 466
S ++ + GN+ G D +++L + K +R HT LS +D+
Sbjct: 97 SSWVMTCAYAPSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHT-GYLSCCRFLDDN 155
Query: 467 QIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWH 646
IV+ S D T LW+ + T+ GH+ + SP+ + +S D + K+W
Sbjct: 156 NIVTSSGDTTCALWDIETGQQKTVFV-GHTGDCMSLAVSPDFN--LFISGACDASAKLWD 212
Query: 647 LTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ + GH +N + P+G +G D L+DL + L
Sbjct: 213 VREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQEL 261
Score = 66.5 bits (155), Expect = 1e-10
Identities = 54/209 (25%), Positives = 88/209 (42%), Gaps = 3/209 (1%)
Frame = +2
Query: 155 NGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSD 334
+ WV A P + + D ++ L E N + + L H+ ++S D
Sbjct: 97 SSWVMTCAYAPS-GNFVACGGLDNMCSIYNLKSREGNVKV-SRELSAHTGYLSCCRFLDD 154
Query: 335 GNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNT 514
N S S D T LWD+ G+ F HT D +S+A S D +SG+ D + KLW+
Sbjct: 155 NNIVTS-SGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDV 213
Query: 515 L-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK--LKINHLGH 685
C+ T GH ++ + F PN I + D + +++ L + + +H
Sbjct: 214 REGTCRQTF--TGHESDINAICFFPN--GEAICTGSDDASCRLFDLRADQELICFSHESI 269
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ +V S G L +G D +WD
Sbjct: 270 ICGITSVAFSLSGRLLFAGYDDFNCNVWD 298
Score = 60.9 bits (141), Expect = 5e-09
Identities = 46/193 (23%), Positives = 88/193 (45%), Gaps = 3/193 (1%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLY-GHSHFISDVVLSSDGNYALSGSWDKTLRL 379
I++SS D T +W + + QK ++ GH+ + +S D N +SG+ D + +L
Sbjct: 157 IVTSSGDTTCALWDIETGQ------QKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKL 210
Query: 380 WDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYT-IQDDGHS 556
WD+ G + F H D+ ++ F + I +GS D + +L++ A+ + +
Sbjct: 211 WDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESII 270
Query: 557 DWVSCVRFSPNHANPIIVSCGWDR-TVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLC 733
++ V FS + ++ G+D VW + GH ++ + V+ DG
Sbjct: 271 CGITSVAFSLSGR---LLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAV 327
Query: 734 ASGGKDMXAMLWD 772
A+G D +W+
Sbjct: 328 ATGSWDSFLKIWN 340
Score = 60.5 bits (140), Expect = 7e-09
Identities = 47/179 (26%), Positives = 86/179 (48%), Gaps = 3/179 (1%)
Frame = +2
Query: 119 ETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGH 298
ET + + GH G +A +P + ++ +S + D + +W + G ++ GH
Sbjct: 172 ETGQQKTVFVGHTGDCMSLAVSPDF-NLFISGACDASAKLWDVRE-----GTCRQTFTGH 225
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRF--EDHTKDVLSVAFSVDNRQI 472
I+ + +G +GS D + RL+DL A + F E + SVAFS+ R +
Sbjct: 226 ESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRLL 285
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCG-WDRTVKVWH 646
+G D +W+++ + I GH + VSC+ + A+ + V+ G WD +K+W+
Sbjct: 286 FAGYDDFNCNVWDSMKSERVGIL-SGHDNRVSCLGVT---ADGMAVATGSWDSFLKIWN 340
>M31328-1|AAA52582.1| 340|Homo sapiens GNB3 protein.
Length = 340
Score = 70.5 bits (165), Expect = 6e-12
Identities = 58/229 (25%), Positives = 100/229 (43%), Gaps = 6/229 (2%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQI--ATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGH 298
++ R TLRGH + + AT+ K +++S+S+D LIVW + IP +
Sbjct: 45 MRTRRTLRGHLAKIYAMHWATDSK---LLVSASQDGKLIVWDSYTTNKVHAIPLR----- 96
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAG----KTTRRFEDHTKDVLSVAFSVDNR 466
S ++ + GN+ G D +++L + K +R HT LS +D+
Sbjct: 97 SSWVMTCAYAPSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHT-GYLSCCRFLDDN 155
Query: 467 QIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWH 646
IV+ S D T LW+ + T+ GH+ + SP+ + +S D + K+W
Sbjct: 156 NIVTSSGDTTCALWDIETGQQKTVFV-GHTGDCMSLAVSPDFN--LFISGACDASAKLWD 212
Query: 647 LTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ + GH +N + P+G +G D L+DL + L
Sbjct: 213 VREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQEL 261
Score = 66.5 bits (155), Expect = 1e-10
Identities = 54/209 (25%), Positives = 88/209 (42%), Gaps = 3/209 (1%)
Frame = +2
Query: 155 NGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSD 334
+ WV A P + + D ++ L E N + + L H+ ++S D
Sbjct: 97 SSWVMTCAYAPS-GNFVACGGLDNMCSIYNLKSREGNVKV-SRELSAHTGYLSCCRFLDD 154
Query: 335 GNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNT 514
N S S D T LWD+ G+ F HT D +S+A S D +SG+ D + KLW+
Sbjct: 155 NNIVTS-SGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDV 213
Query: 515 L-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK--LKINHLGH 685
C+ T GH ++ + F PN I + D + +++ L + + +H
Sbjct: 214 REGTCRQTF--TGHESDINAICFFPN--GEAICTGSDDASCRLFDLRADQELICFSHESI 269
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ +V S G L +G D +WD
Sbjct: 270 ICGITSVAFSLSGRLLFAGYDDFNCNVWD 298
Score = 60.9 bits (141), Expect = 5e-09
Identities = 46/193 (23%), Positives = 88/193 (45%), Gaps = 3/193 (1%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLY-GHSHFISDVVLSSDGNYALSGSWDKTLRL 379
I++SS D T +W + + QK ++ GH+ + +S D N +SG+ D + +L
Sbjct: 157 IVTSSGDTTCALWDIETGQ------QKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKL 210
Query: 380 WDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYT-IQDDGHS 556
WD+ G + F H D+ ++ F + I +GS D + +L++ A+ + +
Sbjct: 211 WDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESII 270
Query: 557 DWVSCVRFSPNHANPIIVSCGWDR-TVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLC 733
++ V FS + ++ G+D VW + GH ++ + V+ DG
Sbjct: 271 CGITSVAFSLSGR---LLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAV 327
Query: 734 ASGGKDMXAMLWD 772
A+G D +W+
Sbjct: 328 ATGSWDSFLKIWN 340
Score = 60.5 bits (140), Expect = 7e-09
Identities = 47/179 (26%), Positives = 86/179 (48%), Gaps = 3/179 (1%)
Frame = +2
Query: 119 ETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGH 298
ET + + GH G +A +P + ++ +S + D + +W + G ++ GH
Sbjct: 172 ETGQQKTVFVGHTGDCMSLAVSPDF-NLFISGACDASAKLWDVRE-----GTCRQTFTGH 225
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRF--EDHTKDVLSVAFSVDNRQI 472
I+ + +G +GS D + RL+DL A + F E + SVAFS+ R +
Sbjct: 226 ESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRLL 285
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCG-WDRTVKVWH 646
+G D +W+++ + I GH + VSC+ + A+ + V+ G WD +K+W+
Sbjct: 286 FAGYDDFNCNVWDSMKSERVGIL-SGHDNRVSCLGVT---ADGMAVATGSWDSFLKIWN 340
>BT009800-1|AAP88802.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 3 protein.
Length = 340
Score = 70.5 bits (165), Expect = 6e-12
Identities = 58/229 (25%), Positives = 100/229 (43%), Gaps = 6/229 (2%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQI--ATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGH 298
++ R TLRGH + + AT+ K +++S+S+D LIVW + IP +
Sbjct: 45 MRTRRTLRGHLAKIYAMHWATDSK---LLVSASQDGKLIVWDSYTTNKVHAIPLR----- 96
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAG----KTTRRFEDHTKDVLSVAFSVDNR 466
S ++ + GN+ G D +++L + K +R HT LS +D+
Sbjct: 97 SSWVMTCAYAPSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHT-GYLSCCRFLDDN 155
Query: 467 QIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWH 646
IV+ S D T LW+ + T+ GH+ + SP+ + +S D + K+W
Sbjct: 156 NIVTSSGDTTCALWDIETGQQKTVFV-GHTGDCMSLAVSPDFN--LFISGACDASAKLWD 212
Query: 647 LTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ + GH +N + P+G +G D L+DL + L
Sbjct: 213 VREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQEL 261
Score = 66.9 bits (156), Expect = 8e-11
Identities = 54/209 (25%), Positives = 88/209 (42%), Gaps = 3/209 (1%)
Frame = +2
Query: 155 NGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSD 334
+ WV A P + + D ++ L E N + + L H+ ++S D
Sbjct: 97 SSWVMTCAYAPS-GNFVACGGLDNMCSIYNLKSREGNVKV-SRELSAHTGYLSCCRFLDD 154
Query: 335 GNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNT 514
N S S D T LWD+ G+ F HT D +S+A S D +SG+ D + KLW+
Sbjct: 155 NNIVTS-SGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDV 213
Query: 515 L-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK--LKINHLGH 685
C+ T GH ++ + F PN I + D + +++ L + + +H
Sbjct: 214 REGTCRQTF--TGHESDINAICFFPN--GEAICTGSDDASCRLFDLRADQELICFSHESI 269
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ +V S G L +G D +WD
Sbjct: 270 ICSITSVAFSLSGRLLFAGYDDFNCNVWD 298
Score = 61.3 bits (142), Expect = 4e-09
Identities = 44/192 (22%), Positives = 85/192 (44%), Gaps = 2/192 (1%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLY-GHSHFISDVVLSSDGNYALSGSWDKTLRL 379
I++SS D T +W + + QK ++ GH+ + +S D N +SG+ D + +L
Sbjct: 157 IVTSSGDTTCALWDIETGQ------QKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKL 210
Query: 380 WDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSD 559
WD+ G + F H D+ ++ F + I +GS D + +L++ A+ + H
Sbjct: 211 WDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFS--HES 268
Query: 560 WVSCVRFSPNHANPIIVSCGWDR-TVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCA 736
+ + + ++ G+D VW + GH ++ + V+ DG A
Sbjct: 269 IICSITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVA 328
Query: 737 SGGKDMXAMLWD 772
+G D +W+
Sbjct: 329 TGSWDSFLKIWN 340
Score = 60.9 bits (141), Expect = 5e-09
Identities = 47/179 (26%), Positives = 86/179 (48%), Gaps = 3/179 (1%)
Frame = +2
Query: 119 ETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGH 298
ET + + GH G +A +P + ++ +S + D + +W + G ++ GH
Sbjct: 172 ETGQQKTVFVGHTGDCMSLAVSPDF-NLFISGACDASAKLWDVRE-----GTCRQTFTGH 225
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRF--EDHTKDVLSVAFSVDNRQI 472
I+ + +G +GS D + RL+DL A + F E + SVAFS+ R +
Sbjct: 226 ESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICSITSVAFSLSGRLL 285
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCG-WDRTVKVWH 646
+G D +W+++ + I GH + VSC+ + A+ + V+ G WD +K+W+
Sbjct: 286 FAGYDDFNCNVWDSMKSERVGIL-SGHDNRVSCLGVT---ADGMAVATGSWDSFLKIWN 340
>BT007309-1|AAP35973.1| 425|Homo sapiens retinoblastoma binding
protein 4 protein.
Length = 425
Score = 70.5 bits (165), Expect = 6e-12
Identities = 66/250 (26%), Positives = 118/250 (47%), Gaps = 18/250 (7%)
Frame = +2
Query: 83 ESSLFKPFSKMSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTR--- 253
E F F +S +++ + H G V + P+ P +I + + ++V+ T+
Sbjct: 101 EKGEFGGFGSVSGKIEIEIKIN-HEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPS 159
Query: 254 --DENNYGIPQKRLYGHSHFISDVVLSSD-GNYALSGSWDKTLRLWDLAA----GKTTRR 412
D + P RL GH + + + + LS S D T+ LWD++A GK
Sbjct: 160 KPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDA 219
Query: 413 ---FEDHTKDVLSVAFSVDNRQIV-SGSRDKTIKLWNTLAE--CKYTIQDDGHSDWVSCV 574
F HT V V++ + + + S + D+ + +W+T + K + D H+ V+C+
Sbjct: 220 KTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCL 279
Query: 575 RFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL-GHSGYLNTVTVSP-DGSLCASGGK 748
F+P ++ I+ + D+TV +W L N KLK++ H + V SP + ++ AS G
Sbjct: 280 SFNP-YSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGT 338
Query: 749 DMXAMLWDLN 778
D +WDL+
Sbjct: 339 DRRLNVWDLS 348
>BC075836-1|AAH75836.1| 425|Homo sapiens retinoblastoma binding
protein 4 protein.
Length = 425
Score = 70.5 bits (165), Expect = 6e-12
Identities = 66/250 (26%), Positives = 118/250 (47%), Gaps = 18/250 (7%)
Frame = +2
Query: 83 ESSLFKPFSKMSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTR--- 253
E F F +S +++ + H G V + P+ P +I + + ++V+ T+
Sbjct: 101 EKGEFGGFGSVSGKIEIEIKIN-HEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPS 159
Query: 254 --DENNYGIPQKRLYGHSHFISDVVLSSD-GNYALSGSWDKTLRLWDLAA----GKTTRR 412
D + P RL GH + + + + LS S D T+ LWD++A GK
Sbjct: 160 KPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDA 219
Query: 413 ---FEDHTKDVLSVAFSVDNRQIV-SGSRDKTIKLWNTLAE--CKYTIQDDGHSDWVSCV 574
F HT V V++ + + + S + D+ + +W+T + K + D H+ V+C+
Sbjct: 220 KTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCL 279
Query: 575 RFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL-GHSGYLNTVTVSP-DGSLCASGGK 748
F+P ++ I+ + D+TV +W L N KLK++ H + V SP + ++ AS G
Sbjct: 280 SFNP-YSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGT 338
Query: 749 DMXAMLWDLN 778
D +WDL+
Sbjct: 339 DRRLNVWDLS 348
>BC053904-1|AAH53904.1| 425|Homo sapiens retinoblastoma binding
protein 4 protein.
Length = 425
Score = 70.5 bits (165), Expect = 6e-12
Identities = 66/250 (26%), Positives = 118/250 (47%), Gaps = 18/250 (7%)
Frame = +2
Query: 83 ESSLFKPFSKMSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTR--- 253
E F F +S +++ + H G V + P+ P +I + + ++V+ T+
Sbjct: 101 EKGEFGGFGSVSGKIEIEIKIN-HEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPS 159
Query: 254 --DENNYGIPQKRLYGHSHFISDVVLSSD-GNYALSGSWDKTLRLWDLAA----GKTTRR 412
D + P RL GH + + + + LS S D T+ LWD++A GK
Sbjct: 160 KPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDA 219
Query: 413 ---FEDHTKDVLSVAFSVDNRQIV-SGSRDKTIKLWNTLAE--CKYTIQDDGHSDWVSCV 574
F HT V V++ + + + S + D+ + +W+T + K + D H+ V+C+
Sbjct: 220 KTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCL 279
Query: 575 RFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL-GHSGYLNTVTVSP-DGSLCASGGK 748
F+P ++ I+ + D+TV +W L N KLK++ H + V SP + ++ AS G
Sbjct: 280 SFNP-YSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGT 338
Query: 749 DMXAMLWDLN 778
D +WDL+
Sbjct: 339 DRRLNVWDLS 348
>BC015123-1|AAH15123.1| 365|Homo sapiens Similar to
retinoblastoma-binding protein 4 protein.
Length = 365
Score = 70.5 bits (165), Expect = 6e-12
Identities = 66/250 (26%), Positives = 118/250 (47%), Gaps = 18/250 (7%)
Frame = +2
Query: 83 ESSLFKPFSKMSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTR--- 253
E F F +S +++ + H G V + P+ P +I + + ++V+ T+
Sbjct: 41 EKGEFGGFGSVSGKIEIEIKIN-HEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPS 99
Query: 254 --DENNYGIPQKRLYGHSHFISDVVLSSD-GNYALSGSWDKTLRLWDLAA----GKTTRR 412
D + P RL GH + + + + LS S D T+ LWD++A GK
Sbjct: 100 KPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDA 159
Query: 413 ---FEDHTKDVLSVAFSVDNRQIV-SGSRDKTIKLWNTLAE--CKYTIQDDGHSDWVSCV 574
F HT V V++ + + + S + D+ + +W+T + K + D H+ V+C+
Sbjct: 160 KTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCL 219
Query: 575 RFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL-GHSGYLNTVTVSP-DGSLCASGGK 748
F+P ++ I+ + D+TV +W L N KLK++ H + V SP + ++ AS G
Sbjct: 220 SFNP-YSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGT 278
Query: 749 DMXAMLWDLN 778
D +WDL+
Sbjct: 279 DRRLNVWDLS 288
>BC003092-1|AAH03092.1| 425|Homo sapiens retinoblastoma binding
protein 4 protein.
Length = 425
Score = 70.5 bits (165), Expect = 6e-12
Identities = 66/250 (26%), Positives = 118/250 (47%), Gaps = 18/250 (7%)
Frame = +2
Query: 83 ESSLFKPFSKMSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTR--- 253
E F F +S +++ + H G V + P+ P +I + + ++V+ T+
Sbjct: 101 EKGEFGGFGSVSGKIEIEIKIN-HEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPS 159
Query: 254 --DENNYGIPQKRLYGHSHFISDVVLSSD-GNYALSGSWDKTLRLWDLAA----GKTTRR 412
D + P RL GH + + + + LS S D T+ LWD++A GK
Sbjct: 160 KPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDA 219
Query: 413 ---FEDHTKDVLSVAFSVDNRQIV-SGSRDKTIKLWNTLAE--CKYTIQDDGHSDWVSCV 574
F HT V V++ + + + S + D+ + +W+T + K + D H+ V+C+
Sbjct: 220 KTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCL 279
Query: 575 RFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL-GHSGYLNTVTVSP-DGSLCASGGK 748
F+P ++ I+ + D+TV +W L N KLK++ H + V SP + ++ AS G
Sbjct: 280 SFNP-YSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGT 338
Query: 749 DMXAMLWDLN 778
D +WDL+
Sbjct: 339 DRRLNVWDLS 348
>BC002454-1|AAH02454.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 3 protein.
Length = 340
Score = 70.5 bits (165), Expect = 6e-12
Identities = 58/229 (25%), Positives = 100/229 (43%), Gaps = 6/229 (2%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQI--ATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGH 298
++ R TLRGH + + AT+ K +++S+S+D LIVW + IP +
Sbjct: 45 MRTRRTLRGHLAKIYAMHWATDSK---LLVSASQDGKLIVWDSYTTNKVHAIPLR----- 96
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAG----KTTRRFEDHTKDVLSVAFSVDNR 466
S ++ + GN+ G D +++L + K +R HT LS +D+
Sbjct: 97 SSWVMTCAYAPSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHT-GYLSCCRFLDDN 155
Query: 467 QIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWH 646
IV+ S D T LW+ + T+ GH+ + SP+ + +S D + K+W
Sbjct: 156 NIVTSSGDTTCALWDIETGQQKTVFV-GHTGDCMSLAVSPDFN--LFISGACDASAKLWD 212
Query: 647 LTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ + GH +N + P+G +G D L+DL + L
Sbjct: 213 VREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQEL 261
Score = 66.9 bits (156), Expect = 8e-11
Identities = 54/209 (25%), Positives = 88/209 (42%), Gaps = 3/209 (1%)
Frame = +2
Query: 155 NGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSD 334
+ WV A P + + D ++ L E N + + L H+ ++S D
Sbjct: 97 SSWVMTCAYAPS-GNFVACGGLDNMCSIYNLKSREGNVKV-SRELSAHTGYLSCCRFLDD 154
Query: 335 GNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNT 514
N S S D T LWD+ G+ F HT D +S+A S D +SG+ D + KLW+
Sbjct: 155 NNIVTS-SGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDV 213
Query: 515 L-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK--LKINHLGH 685
C+ T GH ++ + F PN I + D + +++ L + + +H
Sbjct: 214 REGTCRQTF--TGHESDINAICFFPN--GEAICTGSDDASCRLFDLRADQELICFSHESI 269
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ +V S G L +G D +WD
Sbjct: 270 ICSITSVAFSLSGRLLFAGYDDFNCNVWD 298
Score = 61.3 bits (142), Expect = 4e-09
Identities = 44/192 (22%), Positives = 85/192 (44%), Gaps = 2/192 (1%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLY-GHSHFISDVVLSSDGNYALSGSWDKTLRL 379
I++SS D T +W + + QK ++ GH+ + +S D N +SG+ D + +L
Sbjct: 157 IVTSSGDTTCALWDIETGQ------QKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKL 210
Query: 380 WDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSD 559
WD+ G + F H D+ ++ F + I +GS D + +L++ A+ + H
Sbjct: 211 WDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFS--HES 268
Query: 560 WVSCVRFSPNHANPIIVSCGWDR-TVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCA 736
+ + + ++ G+D VW + GH ++ + V+ DG A
Sbjct: 269 IICSITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVA 328
Query: 737 SGGKDMXAMLWD 772
+G D +W+
Sbjct: 329 TGSWDSFLKIWN 340
Score = 60.9 bits (141), Expect = 5e-09
Identities = 47/179 (26%), Positives = 86/179 (48%), Gaps = 3/179 (1%)
Frame = +2
Query: 119 ETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGH 298
ET + + GH G +A +P + ++ +S + D + +W + G ++ GH
Sbjct: 172 ETGQQKTVFVGHTGDCMSLAVSPDF-NLFISGACDASAKLWDVRE-----GTCRQTFTGH 225
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRF--EDHTKDVLSVAFSVDNRQI 472
I+ + +G +GS D + RL+DL A + F E + SVAFS+ R +
Sbjct: 226 ESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICSITSVAFSLSGRLL 285
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCG-WDRTVKVWH 646
+G D +W+++ + I GH + VSC+ + A+ + V+ G WD +K+W+
Sbjct: 286 FAGYDDFNCNVWDSMKSERVGIL-SGHDNRVSCLGVT---ADGMAVATGSWDSFLKIWN 340
>BC000115-1|AAH00115.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 3 protein.
Length = 340
Score = 70.5 bits (165), Expect = 6e-12
Identities = 58/229 (25%), Positives = 100/229 (43%), Gaps = 6/229 (2%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQI--ATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGH 298
++ R TLRGH + + AT+ K +++S+S+D LIVW + IP +
Sbjct: 45 MRTRRTLRGHLAKIYAMHWATDSK---LLVSASQDGKLIVWDSYTTNKVHAIPLR----- 96
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAG----KTTRRFEDHTKDVLSVAFSVDNR 466
S ++ + GN+ G D +++L + K +R HT LS +D+
Sbjct: 97 SSWVMTCAYAPSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHT-GYLSCCRFLDDN 155
Query: 467 QIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWH 646
IV+ S D T LW+ + T+ GH+ + SP+ + +S D + K+W
Sbjct: 156 NIVTSSGDTTCALWDIETGQQKTVFV-GHTGDCMSLAVSPDFN--LFISGACDASAKLWD 212
Query: 647 LTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ + GH +N + P+G +G D L+DL + L
Sbjct: 213 VREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQEL 261
Score = 66.9 bits (156), Expect = 8e-11
Identities = 54/209 (25%), Positives = 88/209 (42%), Gaps = 3/209 (1%)
Frame = +2
Query: 155 NGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSD 334
+ WV A P + + D ++ L E N + + L H+ ++S D
Sbjct: 97 SSWVMTCAYAPS-GNFVACGGLDNMCSIYNLKSREGNVKV-SRELSAHTGYLSCCRFLDD 154
Query: 335 GNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNT 514
N S S D T LWD+ G+ F HT D +S+A S D +SG+ D + KLW+
Sbjct: 155 NNIVTS-SGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDV 213
Query: 515 L-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK--LKINHLGH 685
C+ T GH ++ + F PN I + D + +++ L + + +H
Sbjct: 214 REGTCRQTF--TGHESDINAICFFPN--GEAICTGSDDASCRLFDLRADQELICFSHESI 269
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ +V S G L +G D +WD
Sbjct: 270 ICSITSVAFSLSGRLLFAGYDDFNCNVWD 298
Score = 61.3 bits (142), Expect = 4e-09
Identities = 44/192 (22%), Positives = 85/192 (44%), Gaps = 2/192 (1%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLY-GHSHFISDVVLSSDGNYALSGSWDKTLRL 379
I++SS D T +W + + QK ++ GH+ + +S D N +SG+ D + +L
Sbjct: 157 IVTSSGDTTCALWDIETGQ------QKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKL 210
Query: 380 WDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSD 559
WD+ G + F H D+ ++ F + I +GS D + +L++ A+ + H
Sbjct: 211 WDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFS--HES 268
Query: 560 WVSCVRFSPNHANPIIVSCGWDR-TVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCA 736
+ + + ++ G+D VW + GH ++ + V+ DG A
Sbjct: 269 IICSITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVA 328
Query: 737 SGGKDMXAMLWD 772
+G D +W+
Sbjct: 329 TGSWDSFLKIWN 340
Score = 60.9 bits (141), Expect = 5e-09
Identities = 47/179 (26%), Positives = 86/179 (48%), Gaps = 3/179 (1%)
Frame = +2
Query: 119 ETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGH 298
ET + + GH G +A +P + ++ +S + D + +W + G ++ GH
Sbjct: 172 ETGQQKTVFVGHTGDCMSLAVSPDF-NLFISGACDASAKLWDVRE-----GTCRQTFTGH 225
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRF--EDHTKDVLSVAFSVDNRQI 472
I+ + +G +GS D + RL+DL A + F E + SVAFS+ R +
Sbjct: 226 ESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICSITSVAFSLSGRLL 285
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCG-WDRTVKVWH 646
+G D +W+++ + I GH + VSC+ + A+ + V+ G WD +K+W+
Sbjct: 286 FAGYDDFNCNVWDSMKSERVGIL-SGHDNRVSCLGVT---ADGMAVATGSWDSFLKIWN 340
>AY631872-1|AAT38116.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 3 protein.
Length = 340
Score = 70.5 bits (165), Expect = 6e-12
Identities = 58/229 (25%), Positives = 100/229 (43%), Gaps = 6/229 (2%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQI--ATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGH 298
++ R TLRGH + + AT+ K +++S+S+D LIVW + IP +
Sbjct: 45 MRTRRTLRGHLAKIYAMHWATDSK---LLVSASQDGKLIVWDSYTTNKVHAIPLR----- 96
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAG----KTTRRFEDHTKDVLSVAFSVDNR 466
S ++ + GN+ G D +++L + K +R HT LS +D+
Sbjct: 97 SSWVMTCAYAPSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHT-GYLSCCRFLDDN 155
Query: 467 QIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWH 646
IV+ S D T LW+ + T+ GH+ + SP+ + +S D + K+W
Sbjct: 156 NIVTSSGDTTCALWDIETGQQKTVFV-GHTGDCMSLAVSPDFN--LFISGACDASAKLWD 212
Query: 647 LTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ + GH +N + P+G +G D L+DL + L
Sbjct: 213 VREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQEL 261
Score = 66.5 bits (155), Expect = 1e-10
Identities = 54/209 (25%), Positives = 88/209 (42%), Gaps = 3/209 (1%)
Frame = +2
Query: 155 NGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSD 334
+ WV A P + + D ++ L E N + + L H+ ++S D
Sbjct: 97 SSWVMTCAYAPS-GNFVACGGLDNMCSIYNLKSREGNVKV-SRELSAHTGYLSCCRFLDD 154
Query: 335 GNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNT 514
N S S D T LWD+ G+ F HT D +S+A S D +SG+ D + KLW+
Sbjct: 155 NNIVTS-SGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDV 213
Query: 515 L-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK--LKINHLGH 685
C+ T GH ++ + F PN I + D + +++ L + + +H
Sbjct: 214 REGTCRQTF--TGHESDINAICFFPN--GEAICTGSDDASCRLFDLRADQELICFSHESI 269
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ +V S G L +G D +WD
Sbjct: 270 ICGITSVAFSLSGRLLFAGYDDFNCNVWD 298
Score = 60.9 bits (141), Expect = 5e-09
Identities = 46/193 (23%), Positives = 88/193 (45%), Gaps = 3/193 (1%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLY-GHSHFISDVVLSSDGNYALSGSWDKTLRL 379
I++SS D T +W + + QK ++ GH+ + +S D N +SG+ D + +L
Sbjct: 157 IVTSSGDTTCALWDIETGQ------QKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKL 210
Query: 380 WDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYT-IQDDGHS 556
WD+ G + F H D+ ++ F + I +GS D + +L++ A+ + +
Sbjct: 211 WDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESII 270
Query: 557 DWVSCVRFSPNHANPIIVSCGWDR-TVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLC 733
++ V FS + ++ G+D VW + GH ++ + V+ DG
Sbjct: 271 CGITSVAFSLSGR---LLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAV 327
Query: 734 ASGGKDMXAMLWD 772
A+G D +W+
Sbjct: 328 ATGSWDSFLKIWN 340
Score = 60.5 bits (140), Expect = 7e-09
Identities = 47/179 (26%), Positives = 86/179 (48%), Gaps = 3/179 (1%)
Frame = +2
Query: 119 ETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGH 298
ET + + GH G +A +P + ++ +S + D + +W + G ++ GH
Sbjct: 172 ETGQQKTVFVGHTGDCMSLAVSPDF-NLFISGACDASAKLWDVRE-----GTCRQTFTGH 225
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRF--EDHTKDVLSVAFSVDNRQI 472
I+ + +G +GS D + RL+DL A + F E + SVAFS+ R +
Sbjct: 226 ESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRLL 285
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCG-WDRTVKVWH 646
+G D +W+++ + I GH + VSC+ + A+ + V+ G WD +K+W+
Sbjct: 286 FAGYDDFNCNVWDSMKSERVGIL-SGHDNRVSCLGVT---ADGMAVATGSWDSFLKIWN 340
>AK222779-1|BAD96499.1| 424|Homo sapiens retinoblastoma binding
protein 4 variant protein.
Length = 424
Score = 70.5 bits (165), Expect = 6e-12
Identities = 66/250 (26%), Positives = 118/250 (47%), Gaps = 18/250 (7%)
Frame = +2
Query: 83 ESSLFKPFSKMSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTR--- 253
E F F +S +++ + H G V + P+ P +I + + ++V+ T+
Sbjct: 100 EKGEFGGFGSVSGKIEIEIKIN-HEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPS 158
Query: 254 --DENNYGIPQKRLYGHSHFISDVVLSSD-GNYALSGSWDKTLRLWDLAA----GKTTRR 412
D + P RL GH + + + + LS S D T+ LWD++A GK
Sbjct: 159 KPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDA 218
Query: 413 ---FEDHTKDVLSVAFSVDNRQIV-SGSRDKTIKLWNTLAE--CKYTIQDDGHSDWVSCV 574
F HT V V++ + + + S + D+ + +W+T + K + D H+ V+C+
Sbjct: 219 KTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCL 278
Query: 575 RFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL-GHSGYLNTVTVSP-DGSLCASGGK 748
F+P ++ I+ + D+TV +W L N KLK++ H + V SP + ++ AS G
Sbjct: 279 SFNP-YSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGT 337
Query: 749 DMXAMLWDLN 778
D +WDL+
Sbjct: 338 DRRLNVWDLS 347
>AF501884-1|AAM15920.1| 340|Homo sapiens guanine nucleotide binding
protein beta 3 protein.
Length = 340
Score = 70.5 bits (165), Expect = 6e-12
Identities = 58/229 (25%), Positives = 100/229 (43%), Gaps = 6/229 (2%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQI--ATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGH 298
++ R TLRGH + + AT+ K +++S+S+D LIVW + IP +
Sbjct: 45 MRTRRTLRGHLAKIYAMHWATDSK---LLVSASQDGKLIVWDSYTTNKVHAIPLR----- 96
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAG----KTTRRFEDHTKDVLSVAFSVDNR 466
S ++ + GN+ G D +++L + K +R HT LS +D+
Sbjct: 97 SSWVMTCAYAPSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHT-GYLSCCRFLDDN 155
Query: 467 QIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWH 646
IV+ S D T LW+ + T+ GH+ + SP+ + +S D + K+W
Sbjct: 156 NIVTSSGDTTCALWDIETGQQKTVFV-GHTGDCMSLAVSPDFN--LFISGACDASAKLWD 212
Query: 647 LTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ + GH +N + P+G +G D L+DL + L
Sbjct: 213 VREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQEL 261
Score = 66.5 bits (155), Expect = 1e-10
Identities = 54/209 (25%), Positives = 88/209 (42%), Gaps = 3/209 (1%)
Frame = +2
Query: 155 NGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSD 334
+ WV A P + + D ++ L E N + + L H+ ++S D
Sbjct: 97 SSWVMTCAYAPS-GNFVACGGLDNMCSIYNLKSREGNVKV-SRELSAHTGYLSCCRFLDD 154
Query: 335 GNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNT 514
N S S D T LWD+ G+ F HT D +S+A S D +SG+ D + KLW+
Sbjct: 155 NNIVTS-SGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDV 213
Query: 515 L-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK--LKINHLGH 685
C+ T GH ++ + F PN I + D + +++ L + + +H
Sbjct: 214 REGTCRQTF--TGHESDINAICFFPN--GEAICTGSDDASCRLFDLRADQELICFSHESI 269
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ +V S G L +G D +WD
Sbjct: 270 ICGITSVAFSLSGRLLFAGYDDFNCNVWD 298
Score = 60.9 bits (141), Expect = 5e-09
Identities = 46/193 (23%), Positives = 88/193 (45%), Gaps = 3/193 (1%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLY-GHSHFISDVVLSSDGNYALSGSWDKTLRL 379
I++SS D T +W + + QK ++ GH+ + +S D N +SG+ D + +L
Sbjct: 157 IVTSSGDTTCALWDIETGQ------QKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKL 210
Query: 380 WDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYT-IQDDGHS 556
WD+ G + F H D+ ++ F + I +GS D + +L++ A+ + +
Sbjct: 211 WDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESII 270
Query: 557 DWVSCVRFSPNHANPIIVSCGWDR-TVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLC 733
++ V FS + ++ G+D VW + GH ++ + V+ DG
Sbjct: 271 CGITSVAFSLSGR---LLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAV 327
Query: 734 ASGGKDMXAMLWD 772
A+G D +W+
Sbjct: 328 ATGSWDSFLKIWN 340
Score = 60.5 bits (140), Expect = 7e-09
Identities = 47/179 (26%), Positives = 86/179 (48%), Gaps = 3/179 (1%)
Frame = +2
Query: 119 ETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGH 298
ET + + GH G +A +P + ++ +S + D + +W + G ++ GH
Sbjct: 172 ETGQQKTVFVGHTGDCMSLAVSPDF-NLFISGACDASAKLWDVRE-----GTCRQTFTGH 225
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRF--EDHTKDVLSVAFSVDNRQI 472
I+ + +G +GS D + RL+DL A + F E + SVAFS+ R +
Sbjct: 226 ESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRLL 285
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCG-WDRTVKVWH 646
+G D +W+++ + I GH + VSC+ + A+ + V+ G WD +K+W+
Sbjct: 286 FAGYDDFNCNVWDSMKSERVGIL-SGHDNRVSCLGVT---ADGMAVATGSWDSFLKIWN 340
>AB209283-1|BAD92520.1| 327|Homo sapiens guanine nucleotide-binding
protein, beta-3 subunit variant protein.
Length = 327
Score = 70.5 bits (165), Expect = 6e-12
Identities = 58/229 (25%), Positives = 100/229 (43%), Gaps = 6/229 (2%)
Frame = +2
Query: 125 LKLRGTLRGHNGWVTQI--ATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGH 298
++ R TLRGH + + AT+ K +++S+S+D LIVW + IP +
Sbjct: 32 MRTRRTLRGHLAKIYAMHWATDSK---LLVSASQDGKLIVWDSYTTNKVHAIPLR----- 83
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAG----KTTRRFEDHTKDVLSVAFSVDNR 466
S ++ + GN+ G D +++L + K +R HT LS +D+
Sbjct: 84 SSWVMTCAYAPSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHT-GYLSCCRFLDDN 142
Query: 467 QIVSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWH 646
IV+ S D T LW+ + T+ GH+ + SP+ + +S D + K+W
Sbjct: 143 NIVTSSGDTTCALWDIETGQQKTVFV-GHTGDCMSLAVSPDFN--LFISGACDASAKLWD 199
Query: 647 LTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
+ + GH +N + P+G +G D L+DL + L
Sbjct: 200 VREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQEL 248
Score = 66.5 bits (155), Expect = 1e-10
Identities = 54/209 (25%), Positives = 88/209 (42%), Gaps = 3/209 (1%)
Frame = +2
Query: 155 NGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSD 334
+ WV A P + + D ++ L E N + + L H+ ++S D
Sbjct: 84 SSWVMTCAYAPS-GNFVACGGLDNMCSIYNLKSREGNVKV-SRELSAHTGYLSCCRFLDD 141
Query: 335 GNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNT 514
N S S D T LWD+ G+ F HT D +S+A S D +SG+ D + KLW+
Sbjct: 142 NNIVTS-SGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDV 200
Query: 515 L-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK--LKINHLGH 685
C+ T GH ++ + F PN I + D + +++ L + + +H
Sbjct: 201 REGTCRQTF--TGHESDINAICFFPN--GEAICTGSDDASCRLFDLRADQELICFSHESI 256
Query: 686 SGYLNTVTVSPDGSLCASGGKDMXAMLWD 772
+ +V S G L +G D +WD
Sbjct: 257 ICGITSVAFSLSGRLLFAGYDDFNCNVWD 285
Score = 60.9 bits (141), Expect = 5e-09
Identities = 46/193 (23%), Positives = 88/193 (45%), Gaps = 3/193 (1%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLY-GHSHFISDVVLSSDGNYALSGSWDKTLRL 379
I++SS D T +W + + QK ++ GH+ + +S D N +SG+ D + +L
Sbjct: 144 IVTSSGDTTCALWDIETGQ------QKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKL 197
Query: 380 WDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYT-IQDDGHS 556
WD+ G + F H D+ ++ F + I +GS D + +L++ A+ + +
Sbjct: 198 WDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESII 257
Query: 557 DWVSCVRFSPNHANPIIVSCGWDR-TVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLC 733
++ V FS + ++ G+D VW + GH ++ + V+ DG
Sbjct: 258 CGITSVAFSLSGR---LLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAV 314
Query: 734 ASGGKDMXAMLWD 772
A+G D +W+
Sbjct: 315 ATGSWDSFLKIWN 327
Score = 60.5 bits (140), Expect = 7e-09
Identities = 47/179 (26%), Positives = 86/179 (48%), Gaps = 3/179 (1%)
Frame = +2
Query: 119 ETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRLYGH 298
ET + + GH G +A +P + ++ +S + D + +W + G ++ GH
Sbjct: 159 ETGQQKTVFVGHTGDCMSLAVSPDF-NLFISGACDASAKLWDVRE-----GTCRQTFTGH 212
Query: 299 SHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRF--EDHTKDVLSVAFSVDNRQI 472
I+ + +G +GS D + RL+DL A + F E + SVAFS+ R +
Sbjct: 213 ESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRLL 272
Query: 473 VSGSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCG-WDRTVKVWH 646
+G D +W+++ + I GH + VSC+ + A+ + V+ G WD +K+W+
Sbjct: 273 FAGYDDFNCNVWDSMKSERVGIL-SGHDNRVSCLGVT---ADGMAVATGSWDSFLKIWN 327
>X72841-1|CAA51360.1| 425|Homo sapiens IEF 7442 protein.
Length = 425
Score = 70.1 bits (164), Expect = 8e-12
Identities = 62/227 (27%), Positives = 109/227 (48%), Gaps = 18/227 (7%)
Frame = +2
Query: 152 HNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTR-----DENNYGIPQKRLYGHSHFISD 316
H G V + P+ P +I + + ++V+ T+ D + P RL GH
Sbjct: 122 HEGEVNRARYMPQNPHIIATKTPSSDVLVFDYTKHPAKPDPSGECNPDLRLRGHQKEGYG 181
Query: 317 VVLSSD-GNYALSGSWDKTLRLWDLAAGKTTRRFED-------HTKDVLSVAFSVDNRQI 472
+ +S+ + LS S D T+ LWD+ AG + D H+ V VA+ + + +
Sbjct: 182 LSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESL 241
Query: 473 V-SGSRDKTIKLWNTLAEC--KYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVW 643
S + D+ + +W+T + K + D H+ V+C+ F+P ++ I+ + D+TV +W
Sbjct: 242 FGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNP-YSEFILATGSADKTVALW 300
Query: 644 HLTNCKLKINHL-GHSGYLNTVTVSP-DGSLCASGGKDMXAMLWDLN 778
L N KLK++ H + V SP + ++ AS G D +WDL+
Sbjct: 301 DLRNLKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLS 347
Score = 65.3 bits (152), Expect = 2e-10
Identities = 52/179 (29%), Positives = 89/179 (49%), Gaps = 9/179 (5%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTR-DENNYGIPQKRLY-GHSHFISD 316
LRGH ++ N +LS+S D T+ +W + + + K ++ GHS + D
Sbjct: 172 LRGHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVED 231
Query: 317 VV--LSSDGNYALSGSWDKTLRLWDLAAGKTTR---RFEDHTKDVLSVAFSVDNRQIV-S 478
V L + + S + D+ L +WD + T++ + HT +V ++F+ + I+ +
Sbjct: 232 VAWHLLHESLFG-SVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILAT 290
Query: 479 GSRDKTIKLWNTLAECKYTIQD-DGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
GS DKT+ LW+ L K + + H D + V +SP H I+ S G DR + VW L+
Sbjct: 291 GSADKTVALWD-LRNLKLKLHTFESHKDEIFQVHWSP-HNETILASSGTDRRLNVWDLS 347
Score = 49.6 bits (113), Expect = 1e-05
Identities = 35/137 (25%), Positives = 65/137 (47%), Gaps = 3/137 (2%)
Frame = +2
Query: 110 KMSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRL 289
K + + + GH+ V +A + + + S + D+ L++W TR N P +
Sbjct: 211 KEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWD-TR-SNTTSKPSHLV 268
Query: 290 YGHSHFISDVVLSSDGNYAL-SGSWDKTLRLWDLAAGK-TTRRFEDHTKDVLSVAFSVDN 463
H+ ++ + + + L +GS DKT+ LWDL K FE H ++ V +S N
Sbjct: 269 DAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHWSPHN 328
Query: 464 RQIVSGS-RDKTIKLWN 511
I++ S D+ + +W+
Sbjct: 329 ETILASSGTDRRLNVWD 345
Score = 31.1 bits (67), Expect = 4.8
Identities = 27/97 (27%), Positives = 43/97 (44%), Gaps = 2/97 (2%)
Frame = +2
Query: 107 SKMSETLKLRGTLRGHNGWVTQIATNPKYPDMILSS-SRDKTLIVWKLTRDENNYGIPQK 283
++ + T K + H V ++ NP Y + IL++ S DKT+ +W D N +
Sbjct: 256 TRSNTTSKPSHLVDAHTAEVNCLSFNP-YSEFILATGSADKTVALW----DLRNLKLKLH 310
Query: 284 RLYGHSHFISDVVLSSDGNYALSGS-WDKTLRLWDLA 391
H I V S L+ S D+ L +WDL+
Sbjct: 311 TFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLS 347
>U35143-1|AAC50231.1| 425|Homo sapiens retinoblastoma-binding
protein RbAp46 protein.
Length = 425
Score = 70.1 bits (164), Expect = 8e-12
Identities = 62/227 (27%), Positives = 109/227 (48%), Gaps = 18/227 (7%)
Frame = +2
Query: 152 HNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTR-----DENNYGIPQKRLYGHSHFISD 316
H G V + P+ P +I + + ++V+ T+ D + P RL GH
Sbjct: 122 HEGEVNRARYMPQNPHIIATKTPSSDVLVFDYTKHPAKPDPSGECNPDLRLRGHQKEGYG 181
Query: 317 VVLSSD-GNYALSGSWDKTLRLWDLAAGKTTRRFED-------HTKDVLSVAFSVDNRQI 472
+ +S+ + LS S D T+ LWD+ AG + D H+ V VA+ + + +
Sbjct: 182 LSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESL 241
Query: 473 V-SGSRDKTIKLWNTLAEC--KYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVW 643
S + D+ + +W+T + K + D H+ V+C+ F+P ++ I+ + D+TV +W
Sbjct: 242 FGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNP-YSEFILATGSADKTVALW 300
Query: 644 HLTNCKLKINHL-GHSGYLNTVTVSP-DGSLCASGGKDMXAMLWDLN 778
L N KLK++ H + V SP + ++ AS G D +WDL+
Sbjct: 301 DLRNLKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLS 347
Score = 65.3 bits (152), Expect = 2e-10
Identities = 52/179 (29%), Positives = 89/179 (49%), Gaps = 9/179 (5%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTR-DENNYGIPQKRLY-GHSHFISD 316
LRGH ++ N +LS+S D T+ +W + + + K ++ GHS + D
Sbjct: 172 LRGHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVED 231
Query: 317 VV--LSSDGNYALSGSWDKTLRLWDLAAGKTTR---RFEDHTKDVLSVAFSVDNRQIV-S 478
V L + + S + D+ L +WD + T++ + HT +V ++F+ + I+ +
Sbjct: 232 VAWHLLHESLFG-SVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILAT 290
Query: 479 GSRDKTIKLWNTLAECKYTIQD-DGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
GS DKT+ LW+ L K + + H D + V +SP H I+ S G DR + VW L+
Sbjct: 291 GSADKTVALWD-LRNLKLKLHTFESHKDEIFQVHWSP-HNETILASSGTDRRLNVWDLS 347
Score = 49.6 bits (113), Expect = 1e-05
Identities = 35/137 (25%), Positives = 65/137 (47%), Gaps = 3/137 (2%)
Frame = +2
Query: 110 KMSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRL 289
K + + + GH+ V +A + + + S + D+ L++W TR N P +
Sbjct: 211 KEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWD-TR-SNTTSKPSHLV 268
Query: 290 YGHSHFISDVVLSSDGNYAL-SGSWDKTLRLWDLAAGK-TTRRFEDHTKDVLSVAFSVDN 463
H+ ++ + + + L +GS DKT+ LWDL K FE H ++ V +S N
Sbjct: 269 DAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHWSPHN 328
Query: 464 RQIVSGS-RDKTIKLWN 511
I++ S D+ + +W+
Sbjct: 329 ETILASSGTDRRLNVWD 345
Score = 31.1 bits (67), Expect = 4.8
Identities = 27/97 (27%), Positives = 43/97 (44%), Gaps = 2/97 (2%)
Frame = +2
Query: 107 SKMSETLKLRGTLRGHNGWVTQIATNPKYPDMILSS-SRDKTLIVWKLTRDENNYGIPQK 283
++ + T K + H V ++ NP Y + IL++ S DKT+ +W D N +
Sbjct: 256 TRSNTTSKPSHLVDAHTAEVNCLSFNP-YSEFILATGSADKTVALW----DLRNLKLKLH 310
Query: 284 RLYGHSHFISDVVLSSDGNYALSGS-WDKTLRLWDLA 391
H I V S L+ S D+ L +WDL+
Sbjct: 311 TFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLS 347
>CR541701-1|CAG46502.1| 425|Homo sapiens RBBP7 protein.
Length = 425
Score = 70.1 bits (164), Expect = 8e-12
Identities = 62/227 (27%), Positives = 109/227 (48%), Gaps = 18/227 (7%)
Frame = +2
Query: 152 HNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTR-----DENNYGIPQKRLYGHSHFISD 316
H G V + P+ P +I + + ++V+ T+ D + P RL GH
Sbjct: 122 HEGEVNRARYMPQNPHIIATKTPSSDVLVFDYTKHPAKPDPSGECNPDLRLRGHQKEGYG 181
Query: 317 VVLSSD-GNYALSGSWDKTLRLWDLAAGKTTRRFED-------HTKDVLSVAFSVDNRQI 472
+ +S+ + LS S D T+ LWD+ AG + D H+ V VA+ + + +
Sbjct: 182 LSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESL 241
Query: 473 V-SGSRDKTIKLWNTLAEC--KYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVW 643
S + D+ + +W+T + K + D H+ V+C+ F+P ++ I+ + D+TV +W
Sbjct: 242 FGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNP-YSEFILATGSADKTVALW 300
Query: 644 HLTNCKLKINHL-GHSGYLNTVTVSP-DGSLCASGGKDMXAMLWDLN 778
L N KLK++ H + V SP + ++ AS G D +WDL+
Sbjct: 301 DLRNLKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLS 347
Score = 65.3 bits (152), Expect = 2e-10
Identities = 52/179 (29%), Positives = 89/179 (49%), Gaps = 9/179 (5%)
Frame = +2
Query: 143 LRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTR-DENNYGIPQKRLY-GHSHFISD 316
LRGH ++ N +LS+S D T+ +W + + + K ++ GHS + D
Sbjct: 172 LRGHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVED 231
Query: 317 VV--LSSDGNYALSGSWDKTLRLWDLAAGKTTR---RFEDHTKDVLSVAFSVDNRQIV-S 478
V L + + S + D+ L +WD + T++ + HT +V ++F+ + I+ +
Sbjct: 232 VAWHLLHESLFG-SVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILAT 290
Query: 479 GSRDKTIKLWNTLAECKYTIQD-DGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 652
GS DKT+ LW+ L K + + H D + V +SP H I+ S G DR + VW L+
Sbjct: 291 GSADKTVALWD-LRNLKLKLHTFESHKDEIFQVHWSP-HNETILASSGTDRRLNVWDLS 347
Score = 49.6 bits (113), Expect = 1e-05
Identities = 35/137 (25%), Positives = 65/137 (47%), Gaps = 3/137 (2%)
Frame = +2
Query: 110 KMSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIPQKRL 289
K + + + GH+ V +A + + + S + D+ L++W TR N P +
Sbjct: 211 KEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWD-TR-SNTTSKPSHLV 268
Query: 290 YGHSHFISDVVLSSDGNYAL-SGSWDKTLRLWDLAAGK-TTRRFEDHTKDVLSVAFSVDN 463
H+ ++ + + + L +GS DKT+ LWDL K FE H ++ V +S N
Sbjct: 269 DAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHWSPHN 328
Query: 464 RQIVSGS-RDKTIKLWN 511
I++ S D+ + +W+
Sbjct: 329 ETILASSGTDRRLNVWD 345
Score = 31.1 bits (67), Expect = 4.8
Identities = 27/97 (27%), Positives = 43/97 (44%), Gaps = 2/97 (2%)
Frame = +2
Query: 107 SKMSETLKLRGTLRGHNGWVTQIATNPKYPDMILSS-SRDKTLIVWKLTRDENNYGIPQK 283
++ + T K + H V ++ NP Y + IL++ S DKT+ +W D N +
Sbjct: 256 TRSNTTSKPSHLVDAHTAEVNCLSFNP-YSEFILATGSADKTVALW----DLRNLKLKLH 310
Query: 284 RLYGHSHFISDVVLSSDGNYALSGS-WDKTLRLWDLA 391
H I V S L+ S D+ L +WDL+
Sbjct: 311 TFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLS 347
>BT020045-1|AAV38848.1| 350|Homo sapiens unr-interacting protein
protein.
Length = 350
Score = 70.1 bits (164), Expect = 8e-12
Identities = 58/235 (24%), Positives = 101/235 (42%), Gaps = 3/235 (1%)
Frame = +2
Query: 98 KPFSKMSETLKLRGTLRGHNGWVTQIATNPKYPDMILSSSRDKTLIVWKLTRDENNYGIP 277
KP + +T GT GH G V N K +++ D T VW +
Sbjct: 40 KPMLRQGDTGDWIGTFLGHKGAVWGATLN-KDATKAATAAADFTAKVWDAVSGD------ 92
Query: 278 QKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKT-TRRFEDHTKDVLSVAFS 454
+ H H + V + D NY L+G DK LR++DL + + HT + +
Sbjct: 93 ELMTLAHKHIVKTVDFTQDSNYLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWC 152
Query: 455 VDNRQIVSGSRDKTIKLWN--TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDR 628
+++QI+S DKT++LW+ T+ E K + VS + + P ++++ G R
Sbjct: 153 SEDKQILSAD-DKTVRLWDHATMTEVKSL----NFNMSVSSMEYIP-EGEILVITYG--R 204
Query: 629 TVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMXAMLWDLNDGKHL 793
++ +H I +N+ ++ P+ +GG+D +D N G+ L
Sbjct: 205 SI-AFHSAVSLDPIKSFEAPATINSASLHPEKEFLVAGGEDFKLYKYDYNSGEEL 258
Score = 47.6 bits (108), Expect = 5e-05
Identities = 48/195 (24%), Positives = 86/195 (44%)
Frame = +2
Query: 203 ILSSSRDKTLIVWKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLW 382
+L+ +DK L ++ L + E K + GH+ I + S+ LS DKT+RLW
Sbjct: 115 LLTGGQDKLLRIYDLNKPEAE----PKEISGHTSGIKKALWCSEDKQILSAD-DKTVRLW 169
Query: 383 DLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLAECKYTIQDDGHSDW 562
D A T + + V S+ + + +I+ + ++I + ++ I+
Sbjct: 170 DHAT-MTEVKSLNFNMSVSSMEY-IPEGEILVITYGRSIAFHSAVS--LDPIKSFEAPAT 225
Query: 563 VSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASG 742
++ P +V+ G D + + + + ++ GH G ++ V SPDG L ASG
Sbjct: 226 INSASLHPE--KEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASG 283
Query: 743 GKDMXAMLWDLNDGK 787
+D LW GK
Sbjct: 284 SEDGTLRLWQTVVGK 298
Score = 41.1 bits (92), Expect = 0.004
Identities = 21/75 (28%), Positives = 35/75 (46%)
Frame = +2
Query: 308 ISDVVLSSDGNYALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSVDNRQIVSGSR 487
I+ L + + ++G D L +D +G+ ++ H + V FS D SGS
Sbjct: 226 INSASLHPEKEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGSE 285
Query: 488 DKTIKLWNTLAECKY 532
D T++LW T+ Y
Sbjct: 286 DGTLRLWQTVVGKTY 300
Score = 38.3 bits (85), Expect = 0.032
Identities = 23/55 (41%), Positives = 27/55 (49%)
Frame = +2
Query: 239 WKLTRDENNYGIPQKRLYGHSHFISDVVLSSDGNYALSGSWDKTLRLWDLAAGKT 403
+KL + + N G + GH I V S DG SGS D TLRLW GKT
Sbjct: 245 FKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLRLWQTVVGKT 299
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 128,867,336
Number of Sequences: 237096
Number of extensions: 2887185
Number of successful extensions: 14563
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 6654
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 10614
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9757565650
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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