Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P05_pT_A05
(535 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X57778-1|CAA40924.1| 359|Homo sapiens E-1 beta subunit of the p... 184 2e-46
M54788-1|AAA60053.1| 359|Homo sapiens pyruvate dehydrogenase E1... 184 2e-46
M34479-1|AAA36428.1| 359|Homo sapiens pyruvate dehydrogenase be... 184 2e-46
M34056-1|AAA60054.1| 335|Homo sapiens PDHB protein. 184 2e-46
M34055-1|AAA60233.1| 359|Homo sapiens PDHB protein. 184 2e-46
CR541911-1|CAG46709.1| 359|Homo sapiens PDHB protein. 184 2e-46
BC001924-1|AAH01924.1| 359|Homo sapiens pyruvate dehydrogenase ... 184 2e-46
BC000439-1|AAH00439.1| 359|Homo sapiens pyruvate dehydrogenase ... 184 2e-46
J03576-1|AAA88097.1| 359|Homo sapiens pyruvate dehydrogenase be... 183 3e-46
D90086-1|BAA14123.1| 359|Homo sapiens pyruvate dehydrogenase be... 183 3e-46
U50708-1|AAB16763.1| 392|Homo sapiens branched chain alpha-keto... 84 3e-16
M55575-1|AAA51812.1| 392|Homo sapiens branched chain alpha-keto... 84 3e-16
D90391-1|BAA14389.1| 392|Homo sapiens E-1-beta subunit of branc... 84 3e-16
BT020063-1|AAV38866.1| 392|Homo sapiens branched chain keto aci... 84 3e-16
BC040139-1|AAH40139.1| 392|Homo sapiens branched chain keto aci... 84 3e-16
AL391595-1|CAI15049.1| 392|Homo sapiens branched chain keto aci... 84 3e-16
AL049696-1|CAC36881.2| 392|Homo sapiens branched chain keto aci... 84 3e-16
X52446-1|CAA36685.1| 373|Homo sapiens protein ( Human mRNA for ... 83 8e-16
Z49258-4|CAH69900.1| 540|Homo sapiens transketolase-like 1 prot... 57 5e-08
Z49258-1|CAH69899.1| 596|Homo sapiens transketolase-like 1 prot... 57 5e-08
BC025382-1|AAH25382.2| 596|Homo sapiens transketolase-like 1 pr... 57 5e-08
CR533560-1|CAG38591.1| 626|Homo sapiens DKFZP434L1717 protein. 56 1e-07
BC142943-1|AAI42944.1| 626|Homo sapiens transketolase-like 2 pr... 56 1e-07
BC125101-1|AAI25102.1| 626|Homo sapiens transketolase-like 2 pr... 56 1e-07
BC028707-1|AAH28707.4| 626|Homo sapiens transketolase-like 2 pr... 56 1e-07
AK057537-1|BAB71524.1| 320|Homo sapiens protein ( Homo sapiens ... 56 1e-07
AK057325-1|BAB71427.1| 626|Homo sapiens protein ( Homo sapiens ... 56 1e-07
Z49258-5|CAI39236.1| 146|Homo sapiens transketolase-like 1 prot... 54 2e-07
X91817-1|CAA62925.1| 557|Homo sapiens transketolase protein. 54 2e-07
AB209241-1|BAD92478.1| 164|Homo sapiens Hypothetical protein DK... 50 4e-06
X67688-1|CAA47919.1| 623|Homo sapiens transketolase protein. 42 0.001
U55017-1|AAA98961.1| 623|Homo sapiens transketolase protein. 42 0.001
BC024026-1|AAH24026.2| 536|Homo sapiens TKT protein protein. 42 0.001
BC009970-1|AAH09970.1| 623|Homo sapiens transketolase (Wernicke... 42 0.001
BC008615-1|AAH08615.1| 395|Homo sapiens Similar to transketolas... 42 0.001
BC002433-1|AAH02433.1| 457|Homo sapiens TKT protein protein. 42 0.001
AK223614-1|BAD97334.1| 623|Homo sapiens transketolase variant p... 42 0.001
L12711-1|AAA61222.1| 623|Homo sapiens transketolase protein. 42 0.002
U51015-1|AAB09779.1| 46|Homo sapiens branched chain alpha-keto... 31 2.6
Y08266-1|CAA69592.1| 191|Homo sapiens DAN15 protein. 29 7.8
>X57778-1|CAA40924.1| 359|Homo sapiens E-1 beta subunit of the
pyruvate dehydrogenase complex protein.
Length = 359
Score = 184 bits (447), Expect = 2e-46
Identities = 84/137 (61%), Positives = 104/137 (75%)
Frame = -1
Query: 535 IXYGIPFPMSDEAQSKDFVLPIGKXKVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIE 356
+ YG+PF EAQSKDF++PIGK K+ER+G HIT V R L+AA L+ +G+E
Sbjct: 204 LMYGVPFEFPPEAQSKDFLIPIGKAKIERQGTHITVVSHSRPVGHCLEAAAVLS-KEGVE 262
Query: 355 CEVVNLRTIRPMDFDTIARSIAKTHHLITVEQGWPQSGIGAEICARVMESPSFFELDAPV 176
CEV+N+RTIRPMD +TI S+ KT+HL+TVE GWPQ G+GAEICAR+ME P+F LDAP
Sbjct: 263 CEVINMRTIRPMDMETIEASVMKTNHLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPA 322
Query: 175 WRVCGADVPMPYARTLE 125
RV GADVPMPYA+ LE
Sbjct: 323 VRVTGADVPMPYAKILE 339
>M54788-1|AAA60053.1| 359|Homo sapiens pyruvate dehydrogenase
E1-beta subunit protein.
Length = 359
Score = 184 bits (447), Expect = 2e-46
Identities = 84/137 (61%), Positives = 104/137 (75%)
Frame = -1
Query: 535 IXYGIPFPMSDEAQSKDFVLPIGKXKVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIE 356
+ YG+PF EAQSKDF++PIGK K+ER+G HIT V R L+AA L+ +G+E
Sbjct: 204 LMYGVPFEFPPEAQSKDFLIPIGKAKIERQGTHITVVSHSRPVGHCLEAAAVLS-KEGVE 262
Query: 355 CEVVNLRTIRPMDFDTIARSIAKTHHLITVEQGWPQSGIGAEICARVMESPSFFELDAPV 176
CEV+N+RTIRPMD +TI S+ KT+HL+TVE GWPQ G+GAEICAR+ME P+F LDAP
Sbjct: 263 CEVINMRTIRPMDMETIEASVMKTNHLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPA 322
Query: 175 WRVCGADVPMPYARTLE 125
RV GADVPMPYA+ LE
Sbjct: 323 VRVTGADVPMPYAKILE 339
>M34479-1|AAA36428.1| 359|Homo sapiens pyruvate dehydrogenase
beta-subunit protein.
Length = 359
Score = 184 bits (447), Expect = 2e-46
Identities = 84/137 (61%), Positives = 104/137 (75%)
Frame = -1
Query: 535 IXYGIPFPMSDEAQSKDFVLPIGKXKVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIE 356
+ YG+PF EAQSKDF++PIGK K+ER+G HIT V R L+AA L+ +G+E
Sbjct: 204 LMYGVPFEFPPEAQSKDFLIPIGKAKIERQGTHITVVSHSRPVGHCLEAAAVLS-KEGVE 262
Query: 355 CEVVNLRTIRPMDFDTIARSIAKTHHLITVEQGWPQSGIGAEICARVMESPSFFELDAPV 176
CEV+N+RTIRPMD +TI S+ KT+HL+TVE GWPQ G+GAEICAR+ME P+F LDAP
Sbjct: 263 CEVINMRTIRPMDMETIEASVMKTNHLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPA 322
Query: 175 WRVCGADVPMPYARTLE 125
RV GADVPMPYA+ LE
Sbjct: 323 VRVTGADVPMPYAKILE 339
>M34056-1|AAA60054.1| 335|Homo sapiens PDHB protein.
Length = 335
Score = 184 bits (447), Expect = 2e-46
Identities = 84/137 (61%), Positives = 104/137 (75%)
Frame = -1
Query: 535 IXYGIPFPMSDEAQSKDFVLPIGKXKVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIE 356
+ YG+PF EAQSKDF++PIGK K+ER+G HIT V R L+AA L+ +G+E
Sbjct: 180 LMYGVPFEFPPEAQSKDFLIPIGKAKIERQGTHITVVSHSRPVGHCLEAAAVLS-KEGVE 238
Query: 355 CEVVNLRTIRPMDFDTIARSIAKTHHLITVEQGWPQSGIGAEICARVMESPSFFELDAPV 176
CEV+N+RTIRPMD +TI S+ KT+HL+TVE GWPQ G+GAEICAR+ME P+F LDAP
Sbjct: 239 CEVINMRTIRPMDMETIEASVMKTNHLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPA 298
Query: 175 WRVCGADVPMPYARTLE 125
RV GADVPMPYA+ LE
Sbjct: 299 VRVTGADVPMPYAKILE 315
>M34055-1|AAA60233.1| 359|Homo sapiens PDHB protein.
Length = 359
Score = 184 bits (447), Expect = 2e-46
Identities = 84/137 (61%), Positives = 104/137 (75%)
Frame = -1
Query: 535 IXYGIPFPMSDEAQSKDFVLPIGKXKVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIE 356
+ YG+PF EAQSKDF++PIGK K+ER+G HIT V R L+AA L+ +G+E
Sbjct: 204 LMYGVPFEFPPEAQSKDFLIPIGKAKIERQGTHITVVSHSRPVGHCLEAAAVLS-KEGVE 262
Query: 355 CEVVNLRTIRPMDFDTIARSIAKTHHLITVEQGWPQSGIGAEICARVMESPSFFELDAPV 176
CEV+N+RTIRPMD +TI S+ KT+HL+TVE GWPQ G+GAEICAR+ME P+F LDAP
Sbjct: 263 CEVINMRTIRPMDMETIEASVMKTNHLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPA 322
Query: 175 WRVCGADVPMPYARTLE 125
RV GADVPMPYA+ LE
Sbjct: 323 VRVTGADVPMPYAKILE 339
>CR541911-1|CAG46709.1| 359|Homo sapiens PDHB protein.
Length = 359
Score = 184 bits (447), Expect = 2e-46
Identities = 84/137 (61%), Positives = 104/137 (75%)
Frame = -1
Query: 535 IXYGIPFPMSDEAQSKDFVLPIGKXKVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIE 356
+ YG+PF EAQSKDF++PIGK K+ER+G HIT V R L+AA L+ +G+E
Sbjct: 204 LMYGVPFEFPPEAQSKDFLIPIGKAKIERQGTHITVVSHSRPVGHCLEAAAVLS-KEGVE 262
Query: 355 CEVVNLRTIRPMDFDTIARSIAKTHHLITVEQGWPQSGIGAEICARVMESPSFFELDAPV 176
CEV+N+RTIRPMD +TI S+ KT+HL+TVE GWPQ G+GAEICAR+ME P+F LDAP
Sbjct: 263 CEVINMRTIRPMDMETIEASVMKTNHLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPA 322
Query: 175 WRVCGADVPMPYARTLE 125
RV GADVPMPYA+ LE
Sbjct: 323 VRVTGADVPMPYAKILE 339
>BC001924-1|AAH01924.1| 359|Homo sapiens pyruvate dehydrogenase
(lipoamide) beta protein.
Length = 359
Score = 184 bits (447), Expect = 2e-46
Identities = 84/137 (61%), Positives = 104/137 (75%)
Frame = -1
Query: 535 IXYGIPFPMSDEAQSKDFVLPIGKXKVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIE 356
+ YG+PF EAQSKDF++PIGK K+ER+G HIT V R L+AA L+ +G+E
Sbjct: 204 LMYGVPFEFPPEAQSKDFLIPIGKAKIERQGTHITVVSHSRPVGHCLEAAAVLS-KEGVE 262
Query: 355 CEVVNLRTIRPMDFDTIARSIAKTHHLITVEQGWPQSGIGAEICARVMESPSFFELDAPV 176
CEV+N+RTIRPMD +TI S+ KT+HL+TVE GWPQ G+GAEICAR+ME P+F LDAP
Sbjct: 263 CEVINMRTIRPMDMETIEASVMKTNHLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPA 322
Query: 175 WRVCGADVPMPYARTLE 125
RV GADVPMPYA+ LE
Sbjct: 323 VRVTGADVPMPYAKILE 339
>BC000439-1|AAH00439.1| 359|Homo sapiens pyruvate dehydrogenase
(lipoamide) beta protein.
Length = 359
Score = 184 bits (447), Expect = 2e-46
Identities = 84/137 (61%), Positives = 104/137 (75%)
Frame = -1
Query: 535 IXYGIPFPMSDEAQSKDFVLPIGKXKVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIE 356
+ YG+PF EAQSKDF++PIGK K+ER+G HIT V R L+AA L+ +G+E
Sbjct: 204 LMYGVPFEFPPEAQSKDFLIPIGKAKIERQGTHITVVSHSRPVGHCLEAAAVLS-KEGVE 262
Query: 355 CEVVNLRTIRPMDFDTIARSIAKTHHLITVEQGWPQSGIGAEICARVMESPSFFELDAPV 176
CEV+N+RTIRPMD +TI S+ KT+HL+TVE GWPQ G+GAEICAR+ME P+F LDAP
Sbjct: 263 CEVINMRTIRPMDMETIEASVMKTNHLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPA 322
Query: 175 WRVCGADVPMPYARTLE 125
RV GADVPMPYA+ LE
Sbjct: 323 VRVTGADVPMPYAKILE 339
>J03576-1|AAA88097.1| 359|Homo sapiens pyruvate dehydrogenase beta
subunit protein.
Length = 359
Score = 183 bits (446), Expect = 3e-46
Identities = 84/137 (61%), Positives = 104/137 (75%)
Frame = -1
Query: 535 IXYGIPFPMSDEAQSKDFVLPIGKXKVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIE 356
+ YG+PF EAQSKDF++PIGK K+ER+G HIT V R L+AA L+ +G+E
Sbjct: 204 LMYGVPFEFLPEAQSKDFLIPIGKAKIERQGTHITVVSHSRPVGHCLEAAAVLS-KEGVE 262
Query: 355 CEVVNLRTIRPMDFDTIARSIAKTHHLITVEQGWPQSGIGAEICARVMESPSFFELDAPV 176
CEV+N+RTIRPMD +TI S+ KT+HL+TVE GWPQ G+GAEICAR+ME P+F LDAP
Sbjct: 263 CEVINMRTIRPMDMETIEASVMKTNHLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPA 322
Query: 175 WRVCGADVPMPYARTLE 125
RV GADVPMPYA+ LE
Sbjct: 323 VRVTGADVPMPYAKILE 339
>D90086-1|BAA14123.1| 359|Homo sapiens pyruvate dehydrogenase beta
subunit protein.
Length = 359
Score = 183 bits (446), Expect = 3e-46
Identities = 84/137 (61%), Positives = 104/137 (75%)
Frame = -1
Query: 535 IXYGIPFPMSDEAQSKDFVLPIGKXKVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIE 356
+ YG+PF EAQSKDF++PIGK K+ER+G HIT V R L+AA L+ +G+E
Sbjct: 204 LMYGVPFEFLPEAQSKDFLIPIGKAKIERQGTHITVVSHSRPVGHCLEAAAVLS-KEGVE 262
Query: 355 CEVVNLRTIRPMDFDTIARSIAKTHHLITVEQGWPQSGIGAEICARVMESPSFFELDAPV 176
CEV+N+RTIRPMD +TI S+ KT+HL+TVE GWPQ G+GAEICAR+ME P+F LDAP
Sbjct: 263 CEVINMRTIRPMDMETIEASVMKTNHLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPA 322
Query: 175 WRVCGADVPMPYARTLE 125
RV GADVPMPYA+ LE
Sbjct: 323 VRVTGADVPMPYAKILE 339
>U50708-1|AAB16763.1| 392|Homo sapiens branched chain
alpha-ketoacid dehydrogenase E1 beta subunit protein.
Length = 392
Score = 84.2 bits (199), Expect = 3e-16
Identities = 42/123 (34%), Positives = 65/123 (52%)
Frame = -1
Query: 508 SDEAQSKDFVLPIGKXKVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTI 329
++E + + +P+ + +V +EG +T V G + A G+ CEV++LRTI
Sbjct: 248 AEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCEVIDLRTI 307
Query: 328 RPMDFDTIARSIAKTHHLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRVCGADVP 149
P D DTI +S+ KT L+ + G +EI + V E F L+AP+ RVCG D P
Sbjct: 308 IPWDVDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQEE-CFLNLEAPISRVCGYDTP 366
Query: 148 MPY 140
P+
Sbjct: 367 FPH 369
>M55575-1|AAA51812.1| 392|Homo sapiens branched chain alpha-keto
acid dehydrogenase E1-beta subunit protein.
Length = 392
Score = 84.2 bits (199), Expect = 3e-16
Identities = 42/123 (34%), Positives = 65/123 (52%)
Frame = -1
Query: 508 SDEAQSKDFVLPIGKXKVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTI 329
++E + + +P+ + +V +EG +T V G + A G+ CEV++LRTI
Sbjct: 248 AEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCEVIDLRTI 307
Query: 328 RPMDFDTIARSIAKTHHLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRVCGADVP 149
P D DTI +S+ KT L+ + G +EI + V E F L+AP+ RVCG D P
Sbjct: 308 IPWDVDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQEE-CFLNLEAPISRVCGYDTP 366
Query: 148 MPY 140
P+
Sbjct: 367 FPH 369
>D90391-1|BAA14389.1| 392|Homo sapiens E-1-beta subunit of branched
chain alpha-keto acid dehydrogenase protein.
Length = 392
Score = 84.2 bits (199), Expect = 3e-16
Identities = 42/123 (34%), Positives = 65/123 (52%)
Frame = -1
Query: 508 SDEAQSKDFVLPIGKXKVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTI 329
++E + + +P+ + +V +EG +T V G + A G+ CEV++LRTI
Sbjct: 248 AEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCEVIDLRTI 307
Query: 328 RPMDFDTIARSIAKTHHLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRVCGADVP 149
P D DTI +S+ KT L+ + G +EI + V E F L+AP+ RVCG D P
Sbjct: 308 IPWDVDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQEE-CFLNLEAPISRVCGYDTP 366
Query: 148 MPY 140
P+
Sbjct: 367 FPH 369
>BT020063-1|AAV38866.1| 392|Homo sapiens branched chain keto acid
dehydrogenase E1, beta polypeptide (maple syrup urine
protein.
Length = 392
Score = 84.2 bits (199), Expect = 3e-16
Identities = 42/123 (34%), Positives = 65/123 (52%)
Frame = -1
Query: 508 SDEAQSKDFVLPIGKXKVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTI 329
++E + + +P+ + +V +EG +T V G + A G+ CEV++LRTI
Sbjct: 248 AEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCEVIDLRTI 307
Query: 328 RPMDFDTIARSIAKTHHLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRVCGADVP 149
P D DTI +S+ KT L+ + G +EI + V E F L+AP+ RVCG D P
Sbjct: 308 IPWDVDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQEE-CFLNLEAPISRVCGYDTP 366
Query: 148 MPY 140
P+
Sbjct: 367 FPH 369
>BC040139-1|AAH40139.1| 392|Homo sapiens branched chain keto acid
dehydrogenase E1, beta polypeptide (maple syrup urine
protein.
Length = 392
Score = 84.2 bits (199), Expect = 3e-16
Identities = 42/123 (34%), Positives = 65/123 (52%)
Frame = -1
Query: 508 SDEAQSKDFVLPIGKXKVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTI 329
++E + + +P+ + +V +EG +T V G + A G+ CEV++LRTI
Sbjct: 248 AEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCEVIDLRTI 307
Query: 328 RPMDFDTIARSIAKTHHLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRVCGADVP 149
P D DTI +S+ KT L+ + G +EI + V E F L+AP+ RVCG D P
Sbjct: 308 IPWDVDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQEE-CFLNLEAPISRVCGYDTP 366
Query: 148 MPY 140
P+
Sbjct: 367 FPH 369
>AL391595-1|CAI15049.1| 392|Homo sapiens branched chain keto acid
dehydrogenase E1, beta polypeptide (maple syrup urine
protein.
Length = 392
Score = 84.2 bits (199), Expect = 3e-16
Identities = 42/123 (34%), Positives = 65/123 (52%)
Frame = -1
Query: 508 SDEAQSKDFVLPIGKXKVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTI 329
++E + + +P+ + +V +EG +T V G + A G+ CEV++LRTI
Sbjct: 248 AEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCEVIDLRTI 307
Query: 328 RPMDFDTIARSIAKTHHLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRVCGADVP 149
P D DTI +S+ KT L+ + G +EI + V E F L+AP+ RVCG D P
Sbjct: 308 IPWDVDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQEE-CFLNLEAPISRVCGYDTP 366
Query: 148 MPY 140
P+
Sbjct: 367 FPH 369
>AL049696-1|CAC36881.2| 392|Homo sapiens branched chain keto acid
dehydrogenase E1, beta polypeptide (maple syrup urine
protein.
Length = 392
Score = 84.2 bits (199), Expect = 3e-16
Identities = 42/123 (34%), Positives = 65/123 (52%)
Frame = -1
Query: 508 SDEAQSKDFVLPIGKXKVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTI 329
++E + + +P+ + +V +EG +T V G + A G+ CEV++LRTI
Sbjct: 248 AEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCEVIDLRTI 307
Query: 328 RPMDFDTIARSIAKTHHLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRVCGADVP 149
P D DTI +S+ KT L+ + G +EI + V E F L+AP+ RVCG D P
Sbjct: 308 IPWDVDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQEE-CFLNLEAPISRVCGYDTP 366
Query: 148 MPY 140
P+
Sbjct: 367 FPH 369
>X52446-1|CAA36685.1| 373|Homo sapiens protein ( Human mRNA for
E1b-beta subunit of the branched-chain complex. ).
Length = 373
Score = 82.6 bits (195), Expect = 8e-16
Identities = 41/123 (33%), Positives = 65/123 (52%)
Frame = -1
Query: 508 SDEAQSKDFVLPIGKXKVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTI 329
++E + + +P+ + +V +EG +T V G + A G+ CEV++LRTI
Sbjct: 229 AEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCEVIDLRTI 288
Query: 328 RPMDFDTIARSIAKTHHLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRVCGADVP 149
P D DTI +S+ K+ L+ + G +EI + V E F L+AP+ RVCG D P
Sbjct: 289 IPWDVDTICKSVIKSGRLLISHEAPLTGGFASEISSTVQEE-CFLNLEAPISRVCGYDTP 347
Query: 148 MPY 140
P+
Sbjct: 348 FPH 350
>Z49258-4|CAH69900.1| 540|Homo sapiens transketolase-like 1
protein.
Length = 540
Score = 56.8 bits (131), Expect = 5e-08
Identities = 37/93 (39%), Positives = 51/93 (54%), Gaps = 3/93 (3%)
Frame = -1
Query: 472 IGKXKVERE--GRHITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIAR 299
IG+ KV R +T + AG AL AA++L+ + I V++L TI+P+D TI
Sbjct: 407 IGQAKVLRHCVSDKVTVIGAGITVYEALAAADELS-KQDIFIRVIDLFTIKPLDVATIVS 465
Query: 298 SIAKTH-HLITVEQGWPQSGIGAEICARVMESP 203
S T +ITVE +PQ GIG +CA V P
Sbjct: 466 SAKATEGRIITVEDHYPQGGIGEAVCAAVSMDP 498
>Z49258-1|CAH69899.1| 596|Homo sapiens transketolase-like 1
protein.
Length = 596
Score = 56.8 bits (131), Expect = 5e-08
Identities = 37/93 (39%), Positives = 51/93 (54%), Gaps = 3/93 (3%)
Frame = -1
Query: 472 IGKXKVERE--GRHITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIAR 299
IG+ KV R +T + AG AL AA++L+ + I V++L TI+P+D TI
Sbjct: 463 IGQAKVLRHCVSDKVTVIGAGITVYEALAAADELS-KQDIFIRVIDLFTIKPLDVATIVS 521
Query: 298 SIAKTH-HLITVEQGWPQSGIGAEICARVMESP 203
S T +ITVE +PQ GIG +CA V P
Sbjct: 522 SAKATEGRIITVEDHYPQGGIGEAVCAAVSMDP 554
>BC025382-1|AAH25382.2| 596|Homo sapiens transketolase-like 1
protein.
Length = 596
Score = 56.8 bits (131), Expect = 5e-08
Identities = 37/93 (39%), Positives = 51/93 (54%), Gaps = 3/93 (3%)
Frame = -1
Query: 472 IGKXKVERE--GRHITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIAR 299
IG+ KV R +T + AG AL AA++L+ + I V++L TI+P+D TI
Sbjct: 463 IGQAKVLRHCVSDKVTVIGAGITVYEALAAADELS-KQDIFIRVIDLFTIKPLDVATIVS 521
Query: 298 SIAKTH-HLITVEQGWPQSGIGAEICARVMESP 203
S T +ITVE +PQ GIG +CA V P
Sbjct: 522 SAKATEGRIITVEDHYPQGGIGEAVCAAVSMDP 554
>CR533560-1|CAG38591.1| 626|Homo sapiens DKFZP434L1717 protein.
Length = 626
Score = 55.6 bits (128), Expect = 1e-07
Identities = 36/93 (38%), Positives = 52/93 (55%), Gaps = 3/93 (3%)
Frame = -1
Query: 472 IGKXKVEREGRH--ITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIAR 299
IG+ KV R G + +T + AG AL+AA+ L+ +GI V++ TI+P+D TI
Sbjct: 493 IGQAKVVRHGVNDKVTVIGAGVTLHEALEAADHLS-QQGISVRVIDPFTIKPLDAATIIS 551
Query: 298 SIAKTH-HLITVEQGWPQSGIGAEICARVMESP 203
S T +ITVE + + GIG +CA V P
Sbjct: 552 SAKATGGRVITVEDHYREGGIGEAVCAAVSREP 584
>BC142943-1|AAI42944.1| 626|Homo sapiens transketolase-like 2
protein.
Length = 626
Score = 55.6 bits (128), Expect = 1e-07
Identities = 36/93 (38%), Positives = 52/93 (55%), Gaps = 3/93 (3%)
Frame = -1
Query: 472 IGKXKVEREGRH--ITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIAR 299
IG+ KV R G + +T + AG AL+AA+ L+ +GI V++ TI+P+D TI
Sbjct: 493 IGQAKVVRHGVNDKVTVIGAGVTLHEALEAADHLS-QQGISVRVIDPFTIKPLDAATIIS 551
Query: 298 SIAKTH-HLITVEQGWPQSGIGAEICARVMESP 203
S T +ITVE + + GIG +CA V P
Sbjct: 552 SAKATGGRVITVEDHYREGGIGEAVCAAVSREP 584
>BC125101-1|AAI25102.1| 626|Homo sapiens transketolase-like 2
protein.
Length = 626
Score = 55.6 bits (128), Expect = 1e-07
Identities = 36/93 (38%), Positives = 52/93 (55%), Gaps = 3/93 (3%)
Frame = -1
Query: 472 IGKXKVEREGRH--ITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIAR 299
IG+ KV R G + +T + AG AL+AA+ L+ +GI V++ TI+P+D TI
Sbjct: 493 IGQAKVVRHGVNDKVTVIGAGVTLHEALEAADHLS-QQGISVRVIDPFTIKPLDAATIIS 551
Query: 298 SIAKTH-HLITVEQGWPQSGIGAEICARVMESP 203
S T +ITVE + + GIG +CA V P
Sbjct: 552 SAKATGGRVITVEDHYREGGIGEAVCAAVSREP 584
>BC028707-1|AAH28707.4| 626|Homo sapiens transketolase-like 2
protein.
Length = 626
Score = 55.6 bits (128), Expect = 1e-07
Identities = 36/93 (38%), Positives = 52/93 (55%), Gaps = 3/93 (3%)
Frame = -1
Query: 472 IGKXKVEREGRH--ITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIAR 299
IG+ KV R G + +T + AG AL+AA+ L+ +GI V++ TI+P+D TI
Sbjct: 493 IGQAKVVRHGVNDKVTVIGAGVTLHEALEAADHLS-QQGISVRVIDPFTIKPLDAATIIS 551
Query: 298 SIAKTH-HLITVEQGWPQSGIGAEICARVMESP 203
S T +ITVE + + GIG +CA V P
Sbjct: 552 SAKATGGRVITVEDHYREGGIGEAVCAAVSREP 584
>AK057537-1|BAB71524.1| 320|Homo sapiens protein ( Homo sapiens
cDNA FLJ32975 fis, clone TESTI2013832, moderately
similar to Xenopus laevis transketolase mRNA. ).
Length = 320
Score = 55.6 bits (128), Expect = 1e-07
Identities = 36/93 (38%), Positives = 52/93 (55%), Gaps = 3/93 (3%)
Frame = -1
Query: 472 IGKXKVEREGRH--ITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIAR 299
IG+ KV R G + +T + AG AL+AA+ L+ +GI V++ TI+P+D TI
Sbjct: 187 IGQAKVVRHGVNDKVTVIGAGVTLHEALEAADHLS-QQGISVRVIDPFTIKPLDAATIIS 245
Query: 298 SIAKTH-HLITVEQGWPQSGIGAEICARVMESP 203
S T +ITVE + + GIG +CA V P
Sbjct: 246 SAKATGGRVITVEDHYREGGIGEAVCAAVSREP 278
>AK057325-1|BAB71427.1| 626|Homo sapiens protein ( Homo sapiens
cDNA FLJ32763 fis, clone TESTI2001827, moderately
similar to TRANSKETOLASE (EC 2.2.1.1). ).
Length = 626
Score = 55.6 bits (128), Expect = 1e-07
Identities = 36/93 (38%), Positives = 52/93 (55%), Gaps = 3/93 (3%)
Frame = -1
Query: 472 IGKXKVEREGRH--ITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIAR 299
IG+ KV R G + +T + AG AL+AA+ L+ +GI V++ TI+P+D TI
Sbjct: 493 IGQAKVVRHGVNDKVTVIGAGVTLHEALEAADHLS-QQGISVRVIDPFTIKPLDAATIIS 551
Query: 298 SIAKTH-HLITVEQGWPQSGIGAEICARVMESP 203
S T +ITVE + + GIG +CA V P
Sbjct: 552 SAKATGGRVITVEDHYREGGIGEAVCAAVSREP 584
>Z49258-5|CAI39236.1| 146|Homo sapiens transketolase-like 1
protein.
Length = 146
Score = 54.4 bits (125), Expect = 2e-07
Identities = 32/79 (40%), Positives = 45/79 (56%), Gaps = 1/79 (1%)
Frame = -1
Query: 436 ITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIARSIAKTH-HLITVEQ 260
+T + AG AL AA++L+ + I V++L TI+P+D TI S T +ITVE
Sbjct: 27 VTVIGAGITVYEALAAADELS-KQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVED 85
Query: 259 GWPQSGIGAEICARVMESP 203
+PQ GIG +CA V P
Sbjct: 86 HYPQGGIGEAVCAAVSMDP 104
>X91817-1|CAA62925.1| 557|Homo sapiens transketolase protein.
Length = 557
Score = 54.4 bits (125), Expect = 2e-07
Identities = 32/79 (40%), Positives = 45/79 (56%), Gaps = 1/79 (1%)
Frame = -1
Query: 436 ITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIARSIAKTH-HLITVEQ 260
+T + AG AL AA++L+ + I V++L TI+P+D TI S T +ITVE
Sbjct: 438 VTVIGAGITVYEALAAADELS-KQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVED 496
Query: 259 GWPQSGIGAEICARVMESP 203
+PQ GIG +CA V P
Sbjct: 497 HYPQGGIGEAVCAAVSMDP 515
>AB209241-1|BAD92478.1| 164|Homo sapiens Hypothetical protein
DKFZp564K0164 variant protein.
Length = 164
Score = 50.4 bits (115), Expect = 4e-06
Identities = 19/32 (59%), Positives = 26/32 (81%)
Frame = -1
Query: 535 IXYGIPFPMSDEAQSKDFVLPIGKXKVEREGR 440
+ YG+PF EAQSKDF++PIGK K+ER+G+
Sbjct: 124 LMYGVPFEFPPEAQSKDFLIPIGKAKIERQGK 155
>X67688-1|CAA47919.1| 623|Homo sapiens transketolase protein.
Length = 623
Score = 41.9 bits (94), Expect = 0.001
Identities = 33/110 (30%), Positives = 52/110 (47%), Gaps = 1/110 (0%)
Frame = -1
Query: 493 SKDFVLPIGKXKVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDF 314
++DF + K ++ + +T + AG AL AAE L K I V++ TI+P+D
Sbjct: 484 NEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEK-INIRVLDPFTIKPLDR 542
Query: 313 DTIARSIAKTH-HLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRV 167
I S T ++TVE + + GIG + + V+ P V RV
Sbjct: 543 KLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRV 592
>U55017-1|AAA98961.1| 623|Homo sapiens transketolase protein.
Length = 623
Score = 41.9 bits (94), Expect = 0.001
Identities = 33/110 (30%), Positives = 52/110 (47%), Gaps = 1/110 (0%)
Frame = -1
Query: 493 SKDFVLPIGKXKVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDF 314
++DF + K ++ + +T + AG AL AAE L K I V++ TI+P+D
Sbjct: 484 NEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEK-INIRVLDPFTIKPLDR 542
Query: 313 DTIARSIAKTH-HLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRV 167
I S T ++TVE + + GIG + + V+ P V RV
Sbjct: 543 KLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRV 592
>BC024026-1|AAH24026.2| 536|Homo sapiens TKT protein protein.
Length = 536
Score = 41.9 bits (94), Expect = 0.001
Identities = 33/110 (30%), Positives = 52/110 (47%), Gaps = 1/110 (0%)
Frame = -1
Query: 493 SKDFVLPIGKXKVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDF 314
++DF + K ++ + +T + AG AL AAE L K I V++ TI+P+D
Sbjct: 397 NEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEK-INIRVLDPFTIKPLDR 455
Query: 313 DTIARSIAKTH-HLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRV 167
I S T ++TVE + + GIG + + V+ P V RV
Sbjct: 456 KLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRV 505
>BC009970-1|AAH09970.1| 623|Homo sapiens transketolase
(Wernicke-Korsakoff syndrome) protein.
Length = 623
Score = 41.9 bits (94), Expect = 0.001
Identities = 33/110 (30%), Positives = 52/110 (47%), Gaps = 1/110 (0%)
Frame = -1
Query: 493 SKDFVLPIGKXKVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDF 314
++DF + K ++ + +T + AG AL AAE L K I V++ TI+P+D
Sbjct: 484 NEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEK-INIRVLDPFTIKPLDR 542
Query: 313 DTIARSIAKTH-HLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRV 167
I S T ++TVE + + GIG + + V+ P V RV
Sbjct: 543 KLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRV 592
>BC008615-1|AAH08615.1| 395|Homo sapiens Similar to transketolase
(Wernicke-Korsakoff syndrome) protein.
Length = 395
Score = 41.9 bits (94), Expect = 0.001
Identities = 33/110 (30%), Positives = 52/110 (47%), Gaps = 1/110 (0%)
Frame = -1
Query: 493 SKDFVLPIGKXKVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDF 314
++DF + K ++ + +T + AG AL AAE L K I V++ TI+P+D
Sbjct: 256 NEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEK-INIRVLDPFTIKPLDR 314
Query: 313 DTIARSIAKTH-HLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRV 167
I S T ++TVE + + GIG + + V+ P V RV
Sbjct: 315 KLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRV 364
>BC002433-1|AAH02433.1| 457|Homo sapiens TKT protein protein.
Length = 457
Score = 41.9 bits (94), Expect = 0.001
Identities = 33/110 (30%), Positives = 52/110 (47%), Gaps = 1/110 (0%)
Frame = -1
Query: 493 SKDFVLPIGKXKVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDF 314
++DF + K ++ + +T + AG AL AAE L K I V++ TI+P+D
Sbjct: 318 NEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEK-INIRVLDPFTIKPLDR 376
Query: 313 DTIARSIAKTH-HLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRV 167
I S T ++TVE + + GIG + + V+ P V RV
Sbjct: 377 KLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRV 426
>AK223614-1|BAD97334.1| 623|Homo sapiens transketolase variant
protein.
Length = 623
Score = 41.9 bits (94), Expect = 0.001
Identities = 33/110 (30%), Positives = 52/110 (47%), Gaps = 1/110 (0%)
Frame = -1
Query: 493 SKDFVLPIGKXKVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDF 314
++DF + K ++ + +T + AG AL AAE L K I V++ TI+P+D
Sbjct: 484 NEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEK-INIRVLDPFTIKPLDR 542
Query: 313 DTIARSIAKTH-HLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRV 167
I S T ++TVE + + GIG + + V+ P V RV
Sbjct: 543 KLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRV 592
>L12711-1|AAA61222.1| 623|Homo sapiens transketolase protein.
Length = 623
Score = 41.5 bits (93), Expect = 0.002
Identities = 30/98 (30%), Positives = 49/98 (50%), Gaps = 1/98 (1%)
Frame = -1
Query: 493 SKDFVLPIGKXKVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDF 314
++DF + K ++ + +T + AG AL AAE L K I V++ TI+P+D
Sbjct: 484 NEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEK-INIRVLDPFTIKPLDR 542
Query: 313 DTIARSIAKTH-HLITVEQGWPQSGIGAEICARVMESP 203
I S T ++TVE + + GIG + + V+ P
Sbjct: 543 KLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEP 580
>U51015-1|AAB09779.1| 46|Homo sapiens branched chain
alpha-ketoacid dehydrogenase E1-beta subunit protein.
Length = 46
Score = 31.1 bits (67), Expect = 2.6
Identities = 11/20 (55%), Positives = 14/20 (70%)
Frame = -1
Query: 199 FFELDAPVWRVCGADVPMPY 140
F L+AP+ RVCG D P P+
Sbjct: 4 FLNLEAPISRVCGYDTPFPH 23
>Y08266-1|CAA69592.1| 191|Homo sapiens DAN15 protein.
Length = 191
Score = 29.5 bits (63), Expect = 7.8
Identities = 14/40 (35%), Positives = 20/40 (50%), Gaps = 2/40 (5%)
Frame = -3
Query: 290 QNTSSHYCRTRMAAIWNRRRDLRPRHGVAVVLR--ARCAG 177
Q +SH+ + ++ RR RPRHG A R +C G
Sbjct: 121 QQQTSHFQQQQLGRRGRRRASARPRHGAAATWRRQGQCCG 160
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 68,919,319
Number of Sequences: 237096
Number of extensions: 1255424
Number of successful extensions: 3305
Number of sequences better than 10.0: 40
Number of HSP's better than 10.0 without gapping: 3218
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3279
length of database: 76,859,062
effective HSP length: 85
effective length of database: 56,705,902
effective search space used: 5216942984
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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