Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P05_F_O12
(870 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC075022-1|AAH75022.1| 543|Homo sapiens potassium channel, subf... 44 7e-04
BC075021-1|AAH75021.1| 543|Homo sapiens potassium channel, subf... 44 7e-04
AF385400-1|AAL95706.1| 543|Homo sapiens potassium channel TREK2... 44 7e-04
AF385399-1|AAL95705.1| 543|Homo sapiens potassium channel TREK2... 44 7e-04
AF279890-1|AAG15191.1| 538|Homo sapiens 2P domain potassium cha... 44 7e-04
BC111860-1|AAI11861.1| 322|Homo sapiens KCNK16 protein protein. 41 0.007
AY253147-1|AAP82868.1| 262|Homo sapiens pancreatic potassium ch... 41 0.007
AY253146-1|AAP82867.1| 322|Homo sapiens pancreatic potassium ch... 41 0.007
AL136087-5|CAI19537.1| 309|Homo sapiens potassium channel, subf... 41 0.007
AF358909-1|AAK49532.1| 309|Homo sapiens 2P domain potassium cha... 41 0.007
EF165335-1|ABM47414.1| 426|Homo sapiens K2P2.1 potassium channe... 39 0.027
EF165334-1|ABM47413.1| 426|Homo sapiens K2P2.1 potassium channe... 39 0.027
BC101695-1|AAI01696.1| 411|Homo sapiens potassium channel, subf... 39 0.027
BC101693-1|AAI01694.1| 411|Homo sapiens potassium channel, subf... 39 0.027
BC069462-1|AAH69462.1| 411|Homo sapiens potassium channel, subf... 39 0.027
AY552981-1|AAT49016.1| 228|Homo sapiens tandem-pore-domain pota... 39 0.027
AY552980-1|AAT49015.1| 422|Homo sapiens tandem-pore-domain pota... 39 0.027
AF171068-1|AAF89743.1| 411|Homo sapiens two-pore domain potassi... 39 0.027
AF129399-1|AAD47569.1| 411|Homo sapiens TREK-1 potassium channe... 39 0.027
AF004711-1|AAD01203.1| 426|Homo sapiens two-pore potassium chan... 39 0.027
AY253145-1|AAP82866.1| 294|Homo sapiens pancreatic potassium ch... 38 0.036
AF336342-1|AAK37518.1| 330|Homo sapiens tandem pore domain pota... 38 0.036
AF294350-1|AAK97091.1| 330|Homo sapiens tandem acid-sensitive p... 38 0.036
AF257081-1|AAG33127.1| 330|Homo sapiens two pore potassium chan... 38 0.036
BC004367-1|AAH04367.1| 313|Homo sapiens potassium channel, subf... 36 0.14
AK222545-1|BAD96265.1| 313|Homo sapiens potassium channel, subf... 36 0.14
AJ297404-1|CAC15489.1| 313|Homo sapiens potassium channel, subf... 36 0.14
AF281302-1|AAG10506.1| 313|Homo sapiens 2P domain K+ channel TW... 36 0.14
AF134149-1|AAD22980.1| 313|Homo sapiens 2-pore K+ channel subun... 36 0.14
AF117708-1|AAD24000.1| 313|Homo sapiens tandem pore domain pota... 36 0.14
BC112065-1|AAI12066.1| 374|Homo sapiens potassium channel, subf... 35 0.33
BC112063-1|AAI12064.1| 374|Homo sapiens potassium channel, subf... 35 0.33
BC093874-1|AAH93874.1| 330|Homo sapiens potassium channel, subf... 35 0.33
BC075080-1|AAH75080.1| 374|Homo sapiens potassium channel, subf... 35 0.33
BC075079-1|AAH75079.1| 374|Homo sapiens potassium channel, subf... 35 0.33
AY190605-1|AAO38739.1| 374|Homo sapiens breast cancer amplified... 35 0.33
AL118522-1|CAC14068.1| 330|Homo sapiens potassium channel, subf... 35 0.33
AF294352-1|AAK97093.1| 330|Homo sapiens tandem acid-sensitive p... 35 0.33
AF294351-1|AAK97092.1| 330|Homo sapiens tandem acid-sensitive p... 35 0.33
AF279809-1|AAF85982.1| 374|Homo sapiens 2P domain potassium cha... 35 0.33
AF257080-1|AAG33126.1| 374|Homo sapiens two pore potassium chan... 35 0.33
AF248241-1|AAG31730.1| 374|Homo sapiens 2P domain potassium cha... 35 0.33
AF212829-1|AAF63708.1| 374|Homo sapiens potassium channel TASK3... 35 0.33
AF186379-1|AAD56250.1| 798|Homo sapiens ligand effect modulator... 35 0.33
AF159714-1|AAD51615.1| 798|Homo sapiens PPAR gamma coactivator-... 35 0.33
AF108205-1|AAF19083.1| 798|Homo sapiens PPAR gamma coactivator-... 35 0.33
AF106698-1|AAF18573.1| 798|Homo sapiens PPAR gamma coactivator-... 35 0.33
AF065163-1|AAG29340.1| 394|Homo sapiens Kcnk3 channel protein. 35 0.33
AF006823-1|AAC51777.1| 394|Homo sapiens TWIK-related acid-sensi... 35 0.33
AC092834-1|AAY41058.1| 798|Homo sapiens unknown protein. 35 0.33
AC015977-1|AAY24312.1| 394|Homo sapiens unknown protein. 35 0.33
BC110327-1|AAI10328.1| 455|Homo sapiens KCNK4 protein protein. 33 1.8
BC033577-1|AAH33577.1| 184|Homo sapiens KCNK4 protein protein. 33 1.8
AF259501-1|AAK49390.1| 419|Homo sapiens two pore K+ channel KT4... 33 1.8
AF259500-1|AAK49389.1| 393|Homo sapiens two pore K+ channel KT4... 33 1.8
AF248242-1|AAG31731.1| 393|Homo sapiens 2P domain potassium cha... 33 1.8
AF247042-1|AAF64062.1| 419|Homo sapiens tandem pore domain pota... 33 1.8
BC069573-1|AAH69573.1| 499|Homo sapiens potassium channel, subf... 32 3.1
BC060793-1|AAH60793.1| 499|Homo sapiens potassium channel, subf... 32 3.1
BC012779-1|AAH12779.1| 408|Homo sapiens potassium channel, subf... 32 3.1
AL731557-4|CAI14827.2| 384|Homo sapiens potassium channel, subf... 32 3.1
AL451185-1|CAH70466.1| 499|Homo sapiens potassium channel, subf... 32 3.1
AF287303-1|AAG32314.1| 408|Homo sapiens tandem pore domain pota... 32 3.1
AF084830-1|AAC79458.1| 499|Homo sapiens two pore domain K+ chan... 32 3.1
AB087138-1|BAC78527.1| 384|Homo sapiens TWIK-related individual... 32 3.1
BC038934-1|AAH38934.1| 261|Homo sapiens gap junction protein, b... 31 7.2
AY297110-1|AAP51162.1| 261|Homo sapiens connexin 30 protein. 31 7.2
AL355984-1|CAI14832.1| 261|Homo sapiens gap junction protein, b... 31 7.2
AJ005585-1|CAA06611.1| 261|Homo sapiens protein ( Homo sapiens ... 31 7.2
>BC075022-1|AAH75022.1| 543|Homo sapiens potassium channel,
subfamily K, member 10, isoform 3 protein.
Length = 543
Score = 44.0 bits (99), Expect = 7e-04
Identities = 33/110 (30%), Positives = 53/110 (48%)
Frame = +2
Query: 539 VGVIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAM 718
V + V+VV Y + G +F+A+E E + +ALE+ AE L +V ++ ET +
Sbjct: 78 VAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEK---AEFLRDHVCVSPQEL-ETLI 133
Query: 719 KERITIELIHYXKKIVFAVRHGWDGGRSSRQWSFSSAFLYSXTVITTIGY 868
+ + + V + +S W SAF ++ TVITTIGY
Sbjct: 134 QHALDADNA--------GVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGY 175
>BC075021-1|AAH75021.1| 543|Homo sapiens potassium channel,
subfamily K, member 10, isoform 3 protein.
Length = 543
Score = 44.0 bits (99), Expect = 7e-04
Identities = 33/110 (30%), Positives = 53/110 (48%)
Frame = +2
Query: 539 VGVIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAM 718
V + V+VV Y + G +F+A+E E + +ALE+ AE L +V ++ ET +
Sbjct: 78 VAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEK---AEFLRDHVCVSPQEL-ETLI 133
Query: 719 KERITIELIHYXKKIVFAVRHGWDGGRSSRQWSFSSAFLYSXTVITTIGY 868
+ + + V + +S W SAF ++ TVITTIGY
Sbjct: 134 QHALDADNA--------GVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGY 175
>AF385400-1|AAL95706.1| 543|Homo sapiens potassium channel TREK2
splice variant c protein.
Length = 543
Score = 44.0 bits (99), Expect = 7e-04
Identities = 33/110 (30%), Positives = 53/110 (48%)
Frame = +2
Query: 539 VGVIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAM 718
V + V+VV Y + G +F+A+E E + +ALE+ AE L +V ++ ET +
Sbjct: 78 VAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEK---AEFLRDHVCVSPQEL-ETLI 133
Query: 719 KERITIELIHYXKKIVFAVRHGWDGGRSSRQWSFSSAFLYSXTVITTIGY 868
+ + + V + +S W SAF ++ TVITTIGY
Sbjct: 134 QHALDADNA--------GVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGY 175
>AF385399-1|AAL95705.1| 543|Homo sapiens potassium channel TREK2
splice variant b protein.
Length = 543
Score = 44.0 bits (99), Expect = 7e-04
Identities = 33/110 (30%), Positives = 53/110 (48%)
Frame = +2
Query: 539 VGVIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAM 718
V + V+VV Y + G +F+A+E E + +ALE+ AE L +V ++ ET +
Sbjct: 78 VAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEK---AEFLRDHVCVSPQEL-ETLI 133
Query: 719 KERITIELIHYXKKIVFAVRHGWDGGRSSRQWSFSSAFLYSXTVITTIGY 868
+ + + V + +S W SAF ++ TVITTIGY
Sbjct: 134 QHALDADNA--------GVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGY 175
>AF279890-1|AAG15191.1| 538|Homo sapiens 2P domain potassium
channel TREK2 protein.
Length = 538
Score = 44.0 bits (99), Expect = 7e-04
Identities = 33/110 (30%), Positives = 53/110 (48%)
Frame = +2
Query: 539 VGVIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAM 718
V + V+VV Y + G +F+A+E E + +ALE+ AE L +V ++ ET +
Sbjct: 73 VAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEK---AEFLRDHVCVSPQEL-ETLI 128
Query: 719 KERITIELIHYXKKIVFAVRHGWDGGRSSRQWSFSSAFLYSXTVITTIGY 868
+ + + V + +S W SAF ++ TVITTIGY
Sbjct: 129 QHALDADNA--------GVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGY 170
>BC111860-1|AAI11861.1| 322|Homo sapiens KCNK16 protein protein.
Length = 322
Score = 40.7 bits (91), Expect = 0.007
Identities = 26/108 (24%), Positives = 51/108 (47%)
Frame = +2
Query: 545 VIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAMKE 724
+++ V Y + GA +FQ +E ++E + LE+ EN ++ AM++
Sbjct: 17 LLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENY--------TCLDQWAMEQ 68
Query: 725 RITIELIHYXKKIVFAVRHGWDGGRSSRQWSFSSAFLYSXTVITTIGY 868
+ + + + K + + + W F S+F ++ TV+TTIGY
Sbjct: 69 FVQVIMEAWVKGV-----NPKGNSTNPSNWDFGSSFFFAGTVVTTIGY 111
>AY253147-1|AAP82868.1| 262|Homo sapiens pancreatic potassium
channel TALK-1d protein.
Length = 262
Score = 40.7 bits (91), Expect = 0.007
Identities = 26/108 (24%), Positives = 51/108 (47%)
Frame = +2
Query: 545 VIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAMKE 724
+++ V Y + GA +FQ +E ++E + LE+ EN ++ AM++
Sbjct: 17 LLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENY--------TCLDQWAMEQ 68
Query: 725 RITIELIHYXKKIVFAVRHGWDGGRSSRQWSFSSAFLYSXTVITTIGY 868
+ + + + K + + + W F S+F ++ TV+TTIGY
Sbjct: 69 FVQVIMEAWVKGV-----NPKGNSTNPSNWDFGSSFFFAGTVVTTIGY 111
>AY253146-1|AAP82867.1| 322|Homo sapiens pancreatic potassium
channel TALK-1c protein.
Length = 322
Score = 40.7 bits (91), Expect = 0.007
Identities = 26/108 (24%), Positives = 51/108 (47%)
Frame = +2
Query: 545 VIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAMKE 724
+++ V Y + GA +FQ +E ++E + LE+ EN ++ AM++
Sbjct: 17 LLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENY--------TCLDQWAMEQ 68
Query: 725 RITIELIHYXKKIVFAVRHGWDGGRSSRQWSFSSAFLYSXTVITTIGY 868
+ + + + K + + + W F S+F ++ TV+TTIGY
Sbjct: 69 FVQVIMEAWVKGV-----NPKGNSTNPSNWDFGSSFFFAGTVVTTIGY 111
>AL136087-5|CAI19537.1| 309|Homo sapiens potassium channel,
subfamily K, member 16 protein.
Length = 309
Score = 40.7 bits (91), Expect = 0.007
Identities = 26/108 (24%), Positives = 51/108 (47%)
Frame = +2
Query: 545 VIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAMKE 724
+++ V Y + GA +FQ +E ++E + LE+ EN ++ AM++
Sbjct: 17 LLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENY--------TCLDQWAMEQ 68
Query: 725 RITIELIHYXKKIVFAVRHGWDGGRSSRQWSFSSAFLYSXTVITTIGY 868
+ + + + K + + + W F S+F ++ TV+TTIGY
Sbjct: 69 FVQVIMEAWVKGV-----NPKGNSTNPSNWDFGSSFFFAGTVVTTIGY 111
>AF358909-1|AAK49532.1| 309|Homo sapiens 2P domain potassium
channel Talk-1 protein.
Length = 309
Score = 40.7 bits (91), Expect = 0.007
Identities = 26/108 (24%), Positives = 51/108 (47%)
Frame = +2
Query: 545 VIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAMKE 724
+++ V Y + GA +FQ +E ++E + LE+ EN ++ AM++
Sbjct: 17 LLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENY--------TCLDQWAMEQ 68
Query: 725 RITIELIHYXKKIVFAVRHGWDGGRSSRQWSFSSAFLYSXTVITTIGY 868
+ + + + K + + + W F S+F ++ TV+TTIGY
Sbjct: 69 FVQVIMEAWVKGV-----NPKGNSTNPSNWDFGSSFFFAGTVVTTIGY 111
>EF165335-1|ABM47414.1| 426|Homo sapiens K2P2.1 potassium channel
protein.
Length = 426
Score = 38.7 bits (86), Expect = 0.027
Identities = 33/112 (29%), Positives = 55/112 (49%), Gaps = 4/112 (3%)
Frame = +2
Query: 545 VIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAMKE 724
+ ++VV Y I GA +F+A+E E+ + T + +++ Q + N T + E
Sbjct: 65 IFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQK--------QTFISQHSCVNSTELDE 116
Query: 725 RITIELIHYXKKIVFAVRHGWDG-GRSSRQ---WSFSSAFLYSXTVITTIGY 868
I ++IV A+ G G +S Q W S+F ++ TVITTIG+
Sbjct: 117 LI--------QQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGF 160
>EF165334-1|ABM47413.1| 426|Homo sapiens K2P2.1 potassium channel
protein.
Length = 426
Score = 38.7 bits (86), Expect = 0.027
Identities = 33/112 (29%), Positives = 55/112 (49%), Gaps = 4/112 (3%)
Frame = +2
Query: 545 VIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAMKE 724
+ ++VV Y I GA +F+A+E E+ + T + +++ Q + N T + E
Sbjct: 65 IFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQK--------QTFISQHSCVNSTELDE 116
Query: 725 RITIELIHYXKKIVFAVRHGWDG-GRSSRQ---WSFSSAFLYSXTVITTIGY 868
I ++IV A+ G G +S Q W S+F ++ TVITTIG+
Sbjct: 117 LI--------QQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGF 160
>BC101695-1|AAI01696.1| 411|Homo sapiens potassium channel,
subfamily K, member 2 protein.
Length = 411
Score = 38.7 bits (86), Expect = 0.027
Identities = 33/112 (29%), Positives = 55/112 (49%), Gaps = 4/112 (3%)
Frame = +2
Query: 545 VIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAMKE 724
+ ++VV Y I GA +F+A+E E+ + T + +++ Q + N T + E
Sbjct: 50 IFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQK--------QTFISQHSCVNSTELDE 101
Query: 725 RITIELIHYXKKIVFAVRHGWDG-GRSSRQ---WSFSSAFLYSXTVITTIGY 868
I ++IV A+ G G +S Q W S+F ++ TVITTIG+
Sbjct: 102 LI--------QQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGF 145
>BC101693-1|AAI01694.1| 411|Homo sapiens potassium channel,
subfamily K, member 2 protein.
Length = 411
Score = 38.7 bits (86), Expect = 0.027
Identities = 33/112 (29%), Positives = 55/112 (49%), Gaps = 4/112 (3%)
Frame = +2
Query: 545 VIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAMKE 724
+ ++VV Y I GA +F+A+E E+ + T + +++ Q + N T + E
Sbjct: 50 IFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQK--------QTFISQHSCVNSTELDE 101
Query: 725 RITIELIHYXKKIVFAVRHGWDG-GRSSRQ---WSFSSAFLYSXTVITTIGY 868
I ++IV A+ G G +S Q W S+F ++ TVITTIG+
Sbjct: 102 LI--------QQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGF 145
>BC069462-1|AAH69462.1| 411|Homo sapiens potassium channel,
subfamily K, member 2 protein.
Length = 411
Score = 38.7 bits (86), Expect = 0.027
Identities = 33/112 (29%), Positives = 55/112 (49%), Gaps = 4/112 (3%)
Frame = +2
Query: 545 VIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAMKE 724
+ ++VV Y I GA +F+A+E E+ + T + +++ Q + N T + E
Sbjct: 50 IFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQK--------QTFISQHSCVNSTELDE 101
Query: 725 RITIELIHYXKKIVFAVRHGWDG-GRSSRQ---WSFSSAFLYSXTVITTIGY 868
I ++IV A+ G G +S Q W S+F ++ TVITTIG+
Sbjct: 102 LI--------QQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGF 145
>AY552981-1|AAT49016.1| 228|Homo sapiens tandem-pore-domain
potassium channel TREK-1 splice variant e protein.
Length = 228
Score = 38.7 bits (86), Expect = 0.027
Identities = 33/112 (29%), Positives = 55/112 (49%), Gaps = 4/112 (3%)
Frame = +2
Query: 545 VIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAMKE 724
+ ++VV Y I GA +F+A+E E+ + T + +++ Q + N T + E
Sbjct: 61 IFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQK--------QTFISQHSCVNSTELDE 112
Query: 725 RITIELIHYXKKIVFAVRHGWDG-GRSSRQ---WSFSSAFLYSXTVITTIGY 868
I ++IV A+ G G +S Q W S+F ++ TVITTIG+
Sbjct: 113 LI--------QQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGF 156
>AY552980-1|AAT49015.1| 422|Homo sapiens tandem-pore-domain
potassium channel TREK-1 splice variant c protein.
Length = 422
Score = 38.7 bits (86), Expect = 0.027
Identities = 33/112 (29%), Positives = 55/112 (49%), Gaps = 4/112 (3%)
Frame = +2
Query: 545 VIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAMKE 724
+ ++VV Y I GA +F+A+E E+ + T + +++ Q + N T + E
Sbjct: 61 IFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQK--------QTFISQHSCVNSTELDE 112
Query: 725 RITIELIHYXKKIVFAVRHGWDG-GRSSRQ---WSFSSAFLYSXTVITTIGY 868
I ++IV A+ G G +S Q W S+F ++ TVITTIG+
Sbjct: 113 LI--------QQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGF 156
>AF171068-1|AAF89743.1| 411|Homo sapiens two-pore domain potassium
channel TREK-1 protein.
Length = 411
Score = 38.7 bits (86), Expect = 0.027
Identities = 33/112 (29%), Positives = 55/112 (49%), Gaps = 4/112 (3%)
Frame = +2
Query: 545 VIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAMKE 724
+ ++VV Y I GA +F+A+E E+ + T + +++ Q + N T + E
Sbjct: 50 IFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQK--------QTFISQHSCVNSTELDE 101
Query: 725 RITIELIHYXKKIVFAVRHGWDG-GRSSRQ---WSFSSAFLYSXTVITTIGY 868
I ++IV A+ G G +S Q W S+F ++ TVITTIG+
Sbjct: 102 LI--------QQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGF 145
>AF129399-1|AAD47569.1| 411|Homo sapiens TREK-1 potassium channel
protein.
Length = 411
Score = 38.7 bits (86), Expect = 0.027
Identities = 33/112 (29%), Positives = 55/112 (49%), Gaps = 4/112 (3%)
Frame = +2
Query: 545 VIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAMKE 724
+ ++VV Y I GA +F+A+E E+ + T + +++ Q + N T + E
Sbjct: 50 IFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQK--------QTFISQHSCVNSTELDE 101
Query: 725 RITIELIHYXKKIVFAVRHGWDG-GRSSRQ---WSFSSAFLYSXTVITTIGY 868
I ++IV A+ G G +S Q W S+F ++ TVITTIG+
Sbjct: 102 LI--------QQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGF 145
>AF004711-1|AAD01203.1| 426|Homo sapiens two-pore potassium channel
TPKC1 protein.
Length = 426
Score = 38.7 bits (86), Expect = 0.027
Identities = 33/112 (29%), Positives = 55/112 (49%), Gaps = 4/112 (3%)
Frame = +2
Query: 545 VIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAMKE 724
+ ++VV Y I GA +F+A+E E+ + T + +++ Q + N T + E
Sbjct: 65 IFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQK--------QTFISQHSCVNSTELDE 116
Query: 725 RITIELIHYXKKIVFAVRHGWDG-GRSSRQ---WSFSSAFLYSXTVITTIGY 868
I ++IV A+ G G +S Q W S+F ++ TVITTIG+
Sbjct: 117 LI--------QQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGF 160
>AY253145-1|AAP82866.1| 294|Homo sapiens pancreatic potassium
channel TALK-1b protein.
Length = 294
Score = 38.3 bits (85), Expect = 0.036
Identities = 25/108 (23%), Positives = 50/108 (46%)
Frame = +2
Query: 545 VIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAMKE 724
+++ V Y + GA +FQ +E ++E + E+ EN ++ AM++
Sbjct: 17 LLLAYVCYLLLGATIFQLLERQAEAQSRDQFQSEKLRFLENY--------TCLDQWAMEQ 68
Query: 725 RITIELIHYXKKIVFAVRHGWDGGRSSRQWSFSSAFLYSXTVITTIGY 868
+ + + + K + + + W F S+F ++ TV+TTIGY
Sbjct: 69 FVQVIMEAWVKGV-----NPKGNSTNPSNWDFGSSFFFAGTVVTTIGY 111
>AF336342-1|AAK37518.1| 330|Homo sapiens tandem pore domain
potassium channel TASK-5 protein.
Length = 330
Score = 38.3 bits (85), Expect = 0.036
Identities = 31/109 (28%), Positives = 51/109 (46%)
Frame = +2
Query: 542 GVIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAMK 721
G+++ + Y + GA +F A+E E+E R + +R L + + + E
Sbjct: 10 GLVLCTLCYLLVGAAVFDALESEAESGRQRLLVQKRGA----LRRKFGFSAEDYREL--- 62
Query: 722 ERITIELIHYXKKIVFAVRHGWDGGRSSRQWSFSSAFLYSXTVITTIGY 868
ER+ ++ A H R+ RQW F +F ++ TVITTIGY
Sbjct: 63 ERLALQ----------AEPH-----RAGRQWKFPGSFYFAITVITTIGY 96
>AF294350-1|AAK97091.1| 330|Homo sapiens tandem acid-sensitive
potassium channel TASK5 protein.
Length = 330
Score = 38.3 bits (85), Expect = 0.036
Identities = 31/109 (28%), Positives = 51/109 (46%)
Frame = +2
Query: 542 GVIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAMK 721
G+++ + Y + GA +F A+E E+E R + +R L + + + E
Sbjct: 10 GLVLCTLCYLLVGAAVFDALESEAESGRQRLLVQKRGA----LRRKFGFSAEDYREL--- 62
Query: 722 ERITIELIHYXKKIVFAVRHGWDGGRSSRQWSFSSAFLYSXTVITTIGY 868
ER+ ++ A H R+ RQW F +F ++ TVITTIGY
Sbjct: 63 ERLALQ----------AEPH-----RAGRQWKFPGSFYFAITVITTIGY 96
>AF257081-1|AAG33127.1| 330|Homo sapiens two pore potassium channel
KT3.3 protein.
Length = 330
Score = 38.3 bits (85), Expect = 0.036
Identities = 31/109 (28%), Positives = 51/109 (46%)
Frame = +2
Query: 542 GVIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAMK 721
G+++ + Y + GA +F A+E E+E R + +R L + + + E
Sbjct: 10 GLVLCTLCYLLVGAAVFDALESEAESGRQRLLVQKRGA----LRRKFGFSAEDYREL--- 62
Query: 722 ERITIELIHYXKKIVFAVRHGWDGGRSSRQWSFSSAFLYSXTVITTIGY 868
ER+ ++ A H R+ RQW F +F ++ TVITTIGY
Sbjct: 63 ERLALQ----------AEPH-----RAGRQWKFPGSFYFAITVITTIGY 96
>BC004367-1|AAH04367.1| 313|Homo sapiens potassium channel,
subfamily K, member 6 protein.
Length = 313
Score = 36.3 bits (80), Expect = 0.14
Identities = 29/109 (26%), Positives = 47/109 (43%)
Frame = +2
Query: 542 GVIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAMK 721
G + AY + GA + +EG E + R A+ L ++ +A + A
Sbjct: 9 GALAAYAAYLVLGALLVARLEGPHEARLRAELETLR---AQLLQRSPCVAAPALD--AFV 63
Query: 722 ERITIELIHYXKKIVFAVRHGWDGGRSSRQWSFSSAFLYSXTVITTIGY 868
ER+ ++V A G S W F+SA ++ T+ITT+GY
Sbjct: 64 ERVLAA--GRLGRVVLANASG-SANASDPAWDFASALFFASTLITTVGY 109
>AK222545-1|BAD96265.1| 313|Homo sapiens potassium channel,
subfamily K, member 6 variant protein.
Length = 313
Score = 36.3 bits (80), Expect = 0.14
Identities = 29/109 (26%), Positives = 47/109 (43%)
Frame = +2
Query: 542 GVIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAMK 721
G + AY + GA + +EG E + R A+ L ++ +A + A
Sbjct: 9 GALAAYAAYLVLGALLVARLEGPHEARLRAELETLR---AQLLQRSPCVAAPALD--AFV 63
Query: 722 ERITIELIHYXKKIVFAVRHGWDGGRSSRQWSFSSAFLYSXTVITTIGY 868
ER+ ++V A G S W F+SA ++ T+ITT+GY
Sbjct: 64 ERVLAA--GRLGRVVLANASG-SANASDPAWDFASALFFASTLITTVGY 109
>AJ297404-1|CAC15489.1| 313|Homo sapiens potassium channel,
subfamily K, member 6 (TWIK-2) protein.
Length = 313
Score = 36.3 bits (80), Expect = 0.14
Identities = 29/109 (26%), Positives = 47/109 (43%)
Frame = +2
Query: 542 GVIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAMK 721
G + AY + GA + +EG E + R A+ L ++ +A + A
Sbjct: 9 GALAAYAAYLVLGALLVARLEGPHEARLRAELETLR---AQLLQRSPCVAAPALD--AFV 63
Query: 722 ERITIELIHYXKKIVFAVRHGWDGGRSSRQWSFSSAFLYSXTVITTIGY 868
ER+ ++V A G S W F+SA ++ T+ITT+GY
Sbjct: 64 ERVLAA--GRLGRVVLANASG-SANASDPAWDFASALFFASTLITTVGY 109
>AF281302-1|AAG10506.1| 313|Homo sapiens 2P domain K+ channel
TWIK-2 protein.
Length = 313
Score = 36.3 bits (80), Expect = 0.14
Identities = 29/109 (26%), Positives = 47/109 (43%)
Frame = +2
Query: 542 GVIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAMK 721
G + AY + GA + +EG E + R A+ L ++ +A + A
Sbjct: 9 GALAAYAAYLVLGALLVARLEGPHEARLRAELETLR---AQLLQRSPCVAAPALD--AFV 63
Query: 722 ERITIELIHYXKKIVFAVRHGWDGGRSSRQWSFSSAFLYSXTVITTIGY 868
ER+ ++V A G S W F+SA ++ T+ITT+GY
Sbjct: 64 ERVLAA--GRLGRVVLANASG-SANASDPAWDFASALFFASTLITTVGY 109
>AF134149-1|AAD22980.1| 313|Homo sapiens 2-pore K+ channel subunit
TOSS protein.
Length = 313
Score = 36.3 bits (80), Expect = 0.14
Identities = 29/109 (26%), Positives = 47/109 (43%)
Frame = +2
Query: 542 GVIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAMK 721
G + AY + GA + +EG E + R A+ L ++ +A + A
Sbjct: 9 GALAAYAAYLVLGALLVARLEGPHEARLRAELETLR---AQLLQRSPCVAAPALD--AFV 63
Query: 722 ERITIELIHYXKKIVFAVRHGWDGGRSSRQWSFSSAFLYSXTVITTIGY 868
ER+ ++V A G S W F+SA ++ T+ITT+GY
Sbjct: 64 ERVLAA--GRLGRVVLANASG-SANASDPAWDFASALFFASTLITTVGY 109
>AF117708-1|AAD24000.1| 313|Homo sapiens tandem pore domain
potassium channel TWIK-2 protein.
Length = 313
Score = 36.3 bits (80), Expect = 0.14
Identities = 29/109 (26%), Positives = 47/109 (43%)
Frame = +2
Query: 542 GVIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAMK 721
G + AY + GA + +EG E + R A+ L ++ +A + A
Sbjct: 9 GALAAYAAYLVLGALLVARLEGPHEARLRAELETLR---AQLLQRSPCVAAPALD--AFV 63
Query: 722 ERITIELIHYXKKIVFAVRHGWDGGRSSRQWSFSSAFLYSXTVITTIGY 868
ER+ ++V A G S W F+SA ++ T+ITT+GY
Sbjct: 64 ERVLAA--GRLGRVVLANASG-SANASDPAWDFASALFFASTLITTVGY 109
>BC112065-1|AAI12066.1| 374|Homo sapiens potassium channel,
subfamily K, member 9 protein.
Length = 374
Score = 35.1 bits (77), Expect = 0.33
Identities = 32/110 (29%), Positives = 52/110 (47%)
Frame = +2
Query: 539 VGVIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAM 718
+ +IV Y + GA +F A+E + EM E AE + + N+ +E
Sbjct: 9 LSLIVCTFTYLLVGAAVFDALESDHEMRE------EEKLKAEEI--RIKGKYNISSEDYR 60
Query: 719 KERITIELIHYXKKIVFAVRHGWDGGRSSRQWSFSSAFLYSXTVITTIGY 868
+ +EL+ I+ + H R+ QW F+ +F ++ TVITTIGY
Sbjct: 61 Q----LELV-----ILQSEPH-----RAGVQWKFAGSFYFAITVITTIGY 96
>BC112063-1|AAI12064.1| 374|Homo sapiens potassium channel,
subfamily K, member 9 protein.
Length = 374
Score = 35.1 bits (77), Expect = 0.33
Identities = 32/110 (29%), Positives = 52/110 (47%)
Frame = +2
Query: 539 VGVIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAM 718
+ +IV Y + GA +F A+E + EM E AE + + N+ +E
Sbjct: 9 LSLIVCTFTYLLVGAAVFDALESDHEMRE------EEKLKAEEI--RIKGKYNISSEDYR 60
Query: 719 KERITIELIHYXKKIVFAVRHGWDGGRSSRQWSFSSAFLYSXTVITTIGY 868
+ +EL+ I+ + H R+ QW F+ +F ++ TVITTIGY
Sbjct: 61 Q----LELV-----ILQSEPH-----RAGVQWKFAGSFYFAITVITTIGY 96
>BC093874-1|AAH93874.1| 330|Homo sapiens potassium channel,
subfamily K, member 15 protein.
Length = 330
Score = 35.1 bits (77), Expect = 0.33
Identities = 30/109 (27%), Positives = 50/109 (45%)
Frame = +2
Query: 542 GVIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAMK 721
G+++ + Y + GA +F A+E E+E R + +R L + + + E
Sbjct: 10 GLVLCTLCYLLVGAAVFDALESEAESGRQRLLVQKRGA----LRRKFGFSAEDYREL--- 62
Query: 722 ERITIELIHYXKKIVFAVRHGWDGGRSSRQWSFSSAFLYSXTVITTIGY 868
ER+ ++ A H R+ RQW F +F ++ TVITTI Y
Sbjct: 63 ERLALQ----------AEPH-----RAGRQWKFPGSFYFAITVITTIEY 96
>BC075080-1|AAH75080.1| 374|Homo sapiens potassium channel,
subfamily K, member 9 protein.
Length = 374
Score = 35.1 bits (77), Expect = 0.33
Identities = 32/110 (29%), Positives = 52/110 (47%)
Frame = +2
Query: 539 VGVIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAM 718
+ +IV Y + GA +F A+E + EM E AE + + N+ +E
Sbjct: 9 LSLIVCTFTYLLVGAAVFDALESDHEMRE------EEKLKAEEI--RIKGKYNISSEDYR 60
Query: 719 KERITIELIHYXKKIVFAVRHGWDGGRSSRQWSFSSAFLYSXTVITTIGY 868
+ +EL+ I+ + H R+ QW F+ +F ++ TVITTIGY
Sbjct: 61 Q----LELV-----ILQSEPH-----RAGVQWKFAGSFYFAITVITTIGY 96
>BC075079-1|AAH75079.1| 374|Homo sapiens potassium channel,
subfamily K, member 9 protein.
Length = 374
Score = 35.1 bits (77), Expect = 0.33
Identities = 32/110 (29%), Positives = 52/110 (47%)
Frame = +2
Query: 539 VGVIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAM 718
+ +IV Y + GA +F A+E + EM E AE + + N+ +E
Sbjct: 9 LSLIVCTFTYLLVGAAVFDALESDHEMRE------EEKLKAEEI--RIKGKYNISSEDYR 60
Query: 719 KERITIELIHYXKKIVFAVRHGWDGGRSSRQWSFSSAFLYSXTVITTIGY 868
+ +EL+ I+ + H R+ QW F+ +F ++ TVITTIGY
Sbjct: 61 Q----LELV-----ILQSEPH-----RAGVQWKFAGSFYFAITVITTIGY 96
>AY190605-1|AAO38739.1| 374|Homo sapiens breast cancer amplified
potassium channel protein.
Length = 374
Score = 35.1 bits (77), Expect = 0.33
Identities = 32/110 (29%), Positives = 52/110 (47%)
Frame = +2
Query: 539 VGVIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAM 718
+ +IV Y + GA +F A+E + EM E AE + + N+ +E
Sbjct: 9 LSLIVCTFTYLLVGAAVFDALESDHEMRE------EEKLKAEEI--RIKGKYNISSEDYR 60
Query: 719 KERITIELIHYXKKIVFAVRHGWDGGRSSRQWSFSSAFLYSXTVITTIGY 868
+ +EL+ I+ + H R+ QW F+ +F ++ TVITTIGY
Sbjct: 61 Q----LELV-----ILQSEPH-----RAGVQWKFAGSFYFAITVITTIGY 96
>AL118522-1|CAC14068.1| 330|Homo sapiens potassium channel,
subfamily K, member 15 protein.
Length = 330
Score = 35.1 bits (77), Expect = 0.33
Identities = 30/109 (27%), Positives = 50/109 (45%)
Frame = +2
Query: 542 GVIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAMK 721
G+++ + Y + GA +F A+E E+E R + +R L + + + E
Sbjct: 10 GLVLCTLCYLLVGAAVFDALESEAESGRQRLLVQKRGA----LRRKFGFSAEDYREL--- 62
Query: 722 ERITIELIHYXKKIVFAVRHGWDGGRSSRQWSFSSAFLYSXTVITTIGY 868
ER+ ++ A H R+ RQW F +F ++ TVITTI Y
Sbjct: 63 ERLALQ----------AEPH-----RAGRQWKFPGSFYFAITVITTIEY 96
>AF294352-1|AAK97093.1| 330|Homo sapiens tandem acid-sensitive
potassium channel TASK5 protein.
Length = 330
Score = 35.1 bits (77), Expect = 0.33
Identities = 30/109 (27%), Positives = 50/109 (45%)
Frame = +2
Query: 542 GVIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAMK 721
G+++ + Y + GA +F A+E E+E R + +R L + + + E
Sbjct: 10 GLVLCTLCYLLVGAAVFDALESEAESGRQRLLVQKRGA----LRRKFGFSAEDYREL--- 62
Query: 722 ERITIELIHYXKKIVFAVRHGWDGGRSSRQWSFSSAFLYSXTVITTIGY 868
ER+ ++ A H R+ RQW F +F ++ TVITTI Y
Sbjct: 63 ERLALQ----------AEPH-----RAGRQWKFPGSFYFAITVITTIEY 96
>AF294351-1|AAK97092.1| 330|Homo sapiens tandem acid-sensitive
potassium channel TASK5 protein.
Length = 330
Score = 35.1 bits (77), Expect = 0.33
Identities = 30/109 (27%), Positives = 50/109 (45%)
Frame = +2
Query: 542 GVIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAMK 721
G+++ + Y + GA +F A+E E+E R + +R L + + + E
Sbjct: 10 GLVLCTLCYLLVGAAVFDALESEAESGRQRLLVQKRGA----LRRKFGFSAEDYREL--- 62
Query: 722 ERITIELIHYXKKIVFAVRHGWDGGRSSRQWSFSSAFLYSXTVITTIGY 868
ER+ ++ A H R+ RQW F +F ++ TVITTI Y
Sbjct: 63 ERLALQ----------AEPH-----RAGRQWKFPGSFYFAITVITTIEY 96
>AF279809-1|AAF85982.1| 374|Homo sapiens 2P domain potassium
channel Task-3 protein.
Length = 374
Score = 35.1 bits (77), Expect = 0.33
Identities = 32/110 (29%), Positives = 52/110 (47%)
Frame = +2
Query: 539 VGVIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAM 718
+ +IV Y + GA +F A+E + EM E AE + + N+ +E
Sbjct: 9 LSLIVCTFTYLLVGAAVFDALESDHEMRE------EEKLKAEEI--RIKGKYNISSEDYR 60
Query: 719 KERITIELIHYXKKIVFAVRHGWDGGRSSRQWSFSSAFLYSXTVITTIGY 868
+ +EL+ I+ + H R+ QW F+ +F ++ TVITTIGY
Sbjct: 61 Q----LELV-----ILQSEPH-----RAGVQWKFAGSFYFAITVITTIGY 96
>AF257080-1|AAG33126.1| 374|Homo sapiens two pore potassium channel
KT3.2 protein.
Length = 374
Score = 35.1 bits (77), Expect = 0.33
Identities = 32/110 (29%), Positives = 52/110 (47%)
Frame = +2
Query: 539 VGVIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAM 718
+ +IV Y + GA +F A+E + EM E AE + + N+ +E
Sbjct: 9 LSLIVCTFTYLLVGAAVFDALESDHEMRE------EEKLKAEEI--RIKGKYNISSEDYR 60
Query: 719 KERITIELIHYXKKIVFAVRHGWDGGRSSRQWSFSSAFLYSXTVITTIGY 868
+ +EL+ I+ + H R+ QW F+ +F ++ TVITTIGY
Sbjct: 61 Q----LELV-----ILQSEPH-----RAGVQWKFAGSFYFAITVITTIGY 96
>AF248241-1|AAG31730.1| 374|Homo sapiens 2P domain potassium
channel protein.
Length = 374
Score = 35.1 bits (77), Expect = 0.33
Identities = 32/110 (29%), Positives = 52/110 (47%)
Frame = +2
Query: 539 VGVIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAM 718
+ +IV Y + GA +F A+E + EM E AE + + N+ +E
Sbjct: 9 LSLIVCTFTYLLVGAAVFDALESDHEMRE------EEKLKAEEI--RIKGKYNISSEDYR 60
Query: 719 KERITIELIHYXKKIVFAVRHGWDGGRSSRQWSFSSAFLYSXTVITTIGY 868
+ +EL+ I+ + H R+ QW F+ +F ++ TVITTIGY
Sbjct: 61 Q----LELV-----ILQSEPH-----RAGVQWKFAGSFYFAITVITTIGY 96
>AF212829-1|AAF63708.1| 374|Homo sapiens potassium channel TASK3
protein.
Length = 374
Score = 35.1 bits (77), Expect = 0.33
Identities = 32/110 (29%), Positives = 52/110 (47%)
Frame = +2
Query: 539 VGVIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAM 718
+ +IV Y + GA +F A+E + EM E AE + + N+ +E
Sbjct: 9 LSLIVCTFTYLLVGAAVFDALESDHEMRE------EEKLKAEEI--RIKGKYNISSEDYR 60
Query: 719 KERITIELIHYXKKIVFAVRHGWDGGRSSRQWSFSSAFLYSXTVITTIGY 868
+ +EL+ I+ + H R+ QW F+ +F ++ TVITTIGY
Sbjct: 61 Q----LELV-----ILQSEPH-----RAGVQWKFAGSFYFAITVITTIGY 96
>AF186379-1|AAD56250.1| 798|Homo sapiens ligand effect modulator-6
protein.
Length = 798
Score = 35.1 bits (77), Expect = 0.33
Identities = 29/127 (22%), Positives = 44/127 (34%)
Frame = +1
Query: 421 CERRAAAVVTMRSYAPSKAQARVAY*SLHTRSPVVPLQQCRGHCTRRRLYYSWCVYVPSY 600
C + ++ S P + ++R S H P + R R C Y S
Sbjct: 547 CRDSVSPPKSLFSQRPQRMRSRSRSFSRHRSCSRSPYSRSRSRSPGSRSSSRSCYYYESS 606
Query: 601 RRRERDGKNDTYGVRKEQHS*EPLAERYSSTQLVQRDCYEREDYYRTNTLSXENRVRCAS 780
R R +N VR S RY S + Q + +RE+Y R R +
Sbjct: 607 HYRHRTHRNSPLYVRSRSRSPYSRRPRYDSYEEYQHERLKREEYRREYEKRESERAKQRE 666
Query: 781 RLGRRPI 801
R ++ I
Sbjct: 667 RQRQKAI 673
>AF159714-1|AAD51615.1| 798|Homo sapiens PPAR gamma coactivator-1
protein.
Length = 798
Score = 35.1 bits (77), Expect = 0.33
Identities = 29/127 (22%), Positives = 44/127 (34%)
Frame = +1
Query: 421 CERRAAAVVTMRSYAPSKAQARVAY*SLHTRSPVVPLQQCRGHCTRRRLYYSWCVYVPSY 600
C + ++ S P + ++R S H P + R R C Y S
Sbjct: 547 CRDSVSPPKSLFSQRPQRMRSRSRSFSRHRSCSRSPYSRSRSRSPGSRSSSRSCYYYESS 606
Query: 601 RRRERDGKNDTYGVRKEQHS*EPLAERYSSTQLVQRDCYEREDYYRTNTLSXENRVRCAS 780
R R +N VR S RY S + Q + +RE+Y R R +
Sbjct: 607 HYRHRTHRNSPLYVRSRSRSPYSRRPRYDSYEEYQHERLKREEYRREYEKRESERAKQRE 666
Query: 781 RLGRRPI 801
R ++ I
Sbjct: 667 RQRQKAI 673
>AF108205-1|AAF19083.1| 798|Homo sapiens PPAR gamma coactivator-1
protein.
Length = 798
Score = 35.1 bits (77), Expect = 0.33
Identities = 29/127 (22%), Positives = 44/127 (34%)
Frame = +1
Query: 421 CERRAAAVVTMRSYAPSKAQARVAY*SLHTRSPVVPLQQCRGHCTRRRLYYSWCVYVPSY 600
C + ++ S P + ++R S H P + R R C Y S
Sbjct: 547 CRDSVSPPKSLFSQRPQRMRSRSRSFSRHRSCSRSPYSRSRSRSPGSRSSSRSCYYYESS 606
Query: 601 RRRERDGKNDTYGVRKEQHS*EPLAERYSSTQLVQRDCYEREDYYRTNTLSXENRVRCAS 780
R R +N VR S RY S + Q + +RE+Y R R +
Sbjct: 607 HYRHRTHRNSPLYVRSRSRSPYSRRPRYDSYEEYQHERLKREEYRREYEKRESERAKQRE 666
Query: 781 RLGRRPI 801
R ++ I
Sbjct: 667 RQRQKAI 673
>AF106698-1|AAF18573.1| 798|Homo sapiens PPAR gamma coactivator-1
protein.
Length = 798
Score = 35.1 bits (77), Expect = 0.33
Identities = 29/127 (22%), Positives = 44/127 (34%)
Frame = +1
Query: 421 CERRAAAVVTMRSYAPSKAQARVAY*SLHTRSPVVPLQQCRGHCTRRRLYYSWCVYVPSY 600
C + ++ S P + ++R S H P + R R C Y S
Sbjct: 547 CRDSVSPPKSLFSQRPQRMRSRSRSFSRHRSCSRSPYSRSRSRSPGSRSSSRSCYYYESS 606
Query: 601 RRRERDGKNDTYGVRKEQHS*EPLAERYSSTQLVQRDCYEREDYYRTNTLSXENRVRCAS 780
R R +N VR S RY S + Q + +RE+Y R R +
Sbjct: 607 HYRHRTHRNSPLYVRSRSRSPYSRRPRYDSYEEYQHERLKREEYRREYEKRESERAKQRE 666
Query: 781 RLGRRPI 801
R ++ I
Sbjct: 667 RQRQKAI 673
>AF065163-1|AAG29340.1| 394|Homo sapiens Kcnk3 channel protein.
Length = 394
Score = 35.1 bits (77), Expect = 0.33
Identities = 29/110 (26%), Positives = 49/110 (44%)
Frame = +2
Query: 539 VGVIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAM 718
+ +IV Y + GA +F A+E E E+ + L + + L L+ + E
Sbjct: 9 LALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQ----QELRARYNLSQGGYEEL-- 62
Query: 719 KERITIELIHYXKKIVFAVRHGWDGGRSSRQWSFSSAFLYSXTVITTIGY 868
ER+ + L + ++ QW F+ +F ++ TVITTIGY
Sbjct: 63 -ERVVLRLKPH---------------KAGVQWRFAGSFYFAITVITTIGY 96
>AF006823-1|AAC51777.1| 394|Homo sapiens TWIK-related
acid-sensitive K+ channel protein.
Length = 394
Score = 35.1 bits (77), Expect = 0.33
Identities = 29/110 (26%), Positives = 49/110 (44%)
Frame = +2
Query: 539 VGVIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAM 718
+ +IV Y + GA +F A+E E E+ + L + + L L+ + E
Sbjct: 9 LALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQ----QELRARYNLSQGGYEEL-- 62
Query: 719 KERITIELIHYXKKIVFAVRHGWDGGRSSRQWSFSSAFLYSXTVITTIGY 868
ER+ + L + ++ QW F+ +F ++ TVITTIGY
Sbjct: 63 -ERVVLRLKPH---------------KAGVQWRFAGSFYFAITVITTIGY 96
>AC092834-1|AAY41058.1| 798|Homo sapiens unknown protein.
Length = 798
Score = 35.1 bits (77), Expect = 0.33
Identities = 29/127 (22%), Positives = 44/127 (34%)
Frame = +1
Query: 421 CERRAAAVVTMRSYAPSKAQARVAY*SLHTRSPVVPLQQCRGHCTRRRLYYSWCVYVPSY 600
C + ++ S P + ++R S H P + R R C Y S
Sbjct: 547 CRDSVSPPKSLFSQRPQRMRSRSRSFSRHRSCSRSPYSRSRSRSPGSRSSSRSCYYYESS 606
Query: 601 RRRERDGKNDTYGVRKEQHS*EPLAERYSSTQLVQRDCYEREDYYRTNTLSXENRVRCAS 780
R R +N VR S RY S + Q + +RE+Y R R +
Sbjct: 607 HYRHRTHRNSPLYVRSRSRSPYSRRPRYDSYEEYQHERLKREEYRREYEKRESERAKQRE 666
Query: 781 RLGRRPI 801
R ++ I
Sbjct: 667 RQRQKAI 673
>AC015977-1|AAY24312.1| 394|Homo sapiens unknown protein.
Length = 394
Score = 35.1 bits (77), Expect = 0.33
Identities = 29/110 (26%), Positives = 49/110 (44%)
Frame = +2
Query: 539 VGVIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAM 718
+ +IV Y + GA +F A+E E E+ + L + + L L+ + E
Sbjct: 9 LALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQ----QELRARYNLSQGGYEEL-- 62
Query: 719 KERITIELIHYXKKIVFAVRHGWDGGRSSRQWSFSSAFLYSXTVITTIGY 868
ER+ + L + ++ QW F+ +F ++ TVITTIGY
Sbjct: 63 -ERVVLRLKPH---------------KAGVQWRFAGSFYFAITVITTIGY 96
>BC110327-1|AAI10328.1| 455|Homo sapiens KCNK4 protein protein.
Length = 455
Score = 32.7 bits (71), Expect = 1.8
Identities = 13/23 (56%), Positives = 15/23 (65%)
Frame = +2
Query: 800 SSRQWSFSSAFLYSXTVITTIGY 868
S W SAF +S T+ITTIGY
Sbjct: 146 SHSAWDLGSAFFFSGTIITTIGY 168
>BC033577-1|AAH33577.1| 184|Homo sapiens KCNK4 protein protein.
Length = 184
Score = 32.7 bits (71), Expect = 1.8
Identities = 13/23 (56%), Positives = 15/23 (65%)
Frame = +2
Query: 800 SSRQWSFSSAFLYSXTVITTIGY 868
S W SAF +S T+ITTIGY
Sbjct: 110 SHSAWDLGSAFFFSGTIITTIGY 132
>AF259501-1|AAK49390.1| 419|Homo sapiens two pore K+ channel KT4.1b
protein.
Length = 419
Score = 32.7 bits (71), Expect = 1.8
Identities = 13/23 (56%), Positives = 15/23 (65%)
Frame = +2
Query: 800 SSRQWSFSSAFLYSXTVITTIGY 868
S W SAF +S T+ITTIGY
Sbjct: 110 SHSAWDLGSAFFFSGTIITTIGY 132
>AF259500-1|AAK49389.1| 393|Homo sapiens two pore K+ channel KT4.1a
protein.
Length = 393
Score = 32.7 bits (71), Expect = 1.8
Identities = 13/23 (56%), Positives = 15/23 (65%)
Frame = +2
Query: 800 SSRQWSFSSAFLYSXTVITTIGY 868
S W SAF +S T+ITTIGY
Sbjct: 84 SHSAWDLGSAFFFSGTIITTIGY 106
>AF248242-1|AAG31731.1| 393|Homo sapiens 2P domain potassium
channel protein.
Length = 393
Score = 32.7 bits (71), Expect = 1.8
Identities = 13/23 (56%), Positives = 15/23 (65%)
Frame = +2
Query: 800 SSRQWSFSSAFLYSXTVITTIGY 868
S W SAF +S T+ITTIGY
Sbjct: 84 SHSAWDLGSAFFFSGTIITTIGY 106
>AF247042-1|AAF64062.1| 419|Homo sapiens tandem pore domain
potassium channel TRAAK protein.
Length = 419
Score = 32.7 bits (71), Expect = 1.8
Identities = 13/23 (56%), Positives = 15/23 (65%)
Frame = +2
Query: 800 SSRQWSFSSAFLYSXTVITTIGY 868
S W SAF +S T+ITTIGY
Sbjct: 110 SHSAWDLGSAFFFSGTIITTIGY 132
>BC069573-1|AAH69573.1| 499|Homo sapiens potassium channel,
subfamily K, member 5 protein.
Length = 499
Score = 31.9 bits (69), Expect = 3.1
Identities = 11/26 (42%), Positives = 19/26 (73%)
Frame = +2
Query: 791 GGRSSRQWSFSSAFLYSXTVITTIGY 868
G ++ W++ +A +++ TVITTIGY
Sbjct: 76 GNQTFNNWNWPNAMIFAATVITTIGY 101
>BC060793-1|AAH60793.1| 499|Homo sapiens potassium channel,
subfamily K, member 5 protein.
Length = 499
Score = 31.9 bits (69), Expect = 3.1
Identities = 11/26 (42%), Positives = 19/26 (73%)
Frame = +2
Query: 791 GGRSSRQWSFSSAFLYSXTVITTIGY 868
G ++ W++ +A +++ TVITTIGY
Sbjct: 76 GNQTFNNWNWPNAMIFAATVITTIGY 101
>BC012779-1|AAH12779.1| 408|Homo sapiens potassium channel,
subfamily K, member 13 protein.
Length = 408
Score = 31.9 bits (69), Expect = 3.1
Identities = 30/105 (28%), Positives = 47/105 (44%)
Frame = +2
Query: 554 LVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAMKERIT 733
L+V Y + GA +F A+E +A ER A+ W+ LA ++ +
Sbjct: 26 LIVLYLLGGAAVFSALE----------LAHERQ--AKQRWEE-RLANFSRGHNLSRDELR 72
Query: 734 IELIHYXKKIVFAVRHGWDGGRSSRQWSFSSAFLYSXTVITTIGY 868
L HY + A R G +W F+ AF + TV++TIG+
Sbjct: 73 GFLRHYEE----ATRAGIRVDNVRPRWDFTGAFYFVGTVVSTIGF 113
>AL731557-4|CAI14827.2| 384|Homo sapiens potassium channel,
subfamily K, member 18 protein.
Length = 384
Score = 31.9 bits (69), Expect = 3.1
Identities = 31/117 (26%), Positives = 52/117 (44%)
Frame = +2
Query: 518 LSFLFSNVGVIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALN 697
L LF + + +V Y + GA +F AIE + +A + + E + + LN
Sbjct: 17 LGKLFPGLCFLCFLVTYALVGAVVFSAIEDGQVL-----VAAD-DGEFEKFLEELCRILN 70
Query: 698 LFNETAMKERITIELIHYXKKIVFAVRHGWDGGRSSRQWSFSSAFLYSXTVITTIGY 868
+ET +++R H K V+ W + WSF S+ + TV +T+GY
Sbjct: 71 C-SETVVEDRKQDLQGHLQK-----VKPQWFN--RTTHWSFLSSLFFCCTVFSTVGY 119
>AL451185-1|CAH70466.1| 499|Homo sapiens potassium channel,
subfamily K, member 5 protein.
Length = 499
Score = 31.9 bits (69), Expect = 3.1
Identities = 11/26 (42%), Positives = 19/26 (73%)
Frame = +2
Query: 791 GGRSSRQWSFSSAFLYSXTVITTIGY 868
G ++ W++ +A +++ TVITTIGY
Sbjct: 76 GNQTFNNWNWPNAMIFAATVITTIGY 101
>AF287303-1|AAG32314.1| 408|Homo sapiens tandem pore domain
potassium channel THIK-1 protein.
Length = 408
Score = 31.9 bits (69), Expect = 3.1
Identities = 30/105 (28%), Positives = 47/105 (44%)
Frame = +2
Query: 554 LVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALNLFNETAMKERIT 733
L+V Y + GA +F A+E +A ER A+ W+ LA ++ +
Sbjct: 26 LIVLYLLGGAAVFSALE----------LAHERQ--AKQRWEE-RLANFSRGHNLSRDELR 72
Query: 734 IELIHYXKKIVFAVRHGWDGGRSSRQWSFSSAFLYSXTVITTIGY 868
L HY + A R G +W F+ AF + TV++TIG+
Sbjct: 73 GFLRHYEE----ATRAGIRVDNVRPRWDFTGAFYFVGTVVSTIGF 113
>AF084830-1|AAC79458.1| 499|Homo sapiens two pore domain K+ channel
protein.
Length = 499
Score = 31.9 bits (69), Expect = 3.1
Identities = 11/26 (42%), Positives = 19/26 (73%)
Frame = +2
Query: 791 GGRSSRQWSFSSAFLYSXTVITTIGY 868
G ++ W++ +A +++ TVITTIGY
Sbjct: 76 GNQTFNNWNWPNAMIFAATVITTIGY 101
>AB087138-1|BAC78527.1| 384|Homo sapiens TWIK-related individual K+
channel protein.
Length = 384
Score = 31.9 bits (69), Expect = 3.1
Identities = 31/117 (26%), Positives = 52/117 (44%)
Frame = +2
Query: 518 LSFLFSNVGVIVLVVAYTIAGAFMFQAIEGESEMERMTHMALERNNTAENLWQNVTLALN 697
L LF + + +V Y + GA +F AIE + +A + + E + + LN
Sbjct: 17 LGKLFPGLCFLCFLVTYALVGAVVFSAIEDGQVL-----VAAD-DGEFEKFLEELCRILN 70
Query: 698 LFNETAMKERITIELIHYXKKIVFAVRHGWDGGRSSRQWSFSSAFLYSXTVITTIGY 868
+ET +++R H K V+ W + WSF S+ + TV +T+GY
Sbjct: 71 C-SETVVEDRKQDLQGHLQK-----VKPQWFN--RTTHWSFLSSLFFCCTVFSTVGY 119
>BC038934-1|AAH38934.1| 261|Homo sapiens gap junction protein, beta
6 protein.
Length = 261
Score = 30.7 bits (66), Expect = 7.2
Identities = 11/22 (50%), Positives = 15/22 (68%)
Frame = -3
Query: 106 YDATLFFKFFFSCHFMYVVYFL 41
Y +++FF+ F FMYV YFL
Sbjct: 136 YTSSIFFRIIFEAAFMYVFYFL 157
>AY297110-1|AAP51162.1| 261|Homo sapiens connexin 30 protein.
Length = 261
Score = 30.7 bits (66), Expect = 7.2
Identities = 11/22 (50%), Positives = 15/22 (68%)
Frame = -3
Query: 106 YDATLFFKFFFSCHFMYVVYFL 41
Y +++FF+ F FMYV YFL
Sbjct: 136 YTSSIFFRIIFEAAFMYVFYFL 157
>AL355984-1|CAI14832.1| 261|Homo sapiens gap junction protein, beta
6 protein.
Length = 261
Score = 30.7 bits (66), Expect = 7.2
Identities = 11/22 (50%), Positives = 15/22 (68%)
Frame = -3
Query: 106 YDATLFFKFFFSCHFMYVVYFL 41
Y +++FF+ F FMYV YFL
Sbjct: 136 YTSSIFFRIIFEAAFMYVFYFL 157
>AJ005585-1|CAA06611.1| 261|Homo sapiens protein ( Homo sapiens
Cx30 gene. ).
Length = 261
Score = 30.7 bits (66), Expect = 7.2
Identities = 11/22 (50%), Positives = 15/22 (68%)
Frame = -3
Query: 106 YDATLFFKFFFSCHFMYVVYFL 41
Y +++FF+ F FMYV YFL
Sbjct: 136 YTSSIFFRIIFEAAFMYVFYFL 157
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 108,836,620
Number of Sequences: 237096
Number of extensions: 2097113
Number of successful extensions: 8535
Number of sequences better than 10.0: 69
Number of HSP's better than 10.0 without gapping: 8305
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8529
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11048563978
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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