Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P05_F_M12
(832 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC007441-1|AAH07441.1| 410|Homo sapiens S-phase kinase-associat... 42 0.004
BC001441-1|AAH01441.1| 410|Homo sapiens S-phase kinase-associat... 42 0.004
AY029177-1|AAK31593.1| 424|Homo sapiens F-box protein SKP2 prot... 42 0.004
AB050981-1|BAB87202.1| 442|Homo sapiens SKP2-like protein type ... 42 0.004
AB050980-1|BAB87201.1| 410|Homo sapiens SKP2-like protein type ... 42 0.004
AB050979-1|BAB87200.1| 424|Homo sapiens SKP2-like protein type ... 42 0.004
U33761-1|AAC50242.1| 435|Homo sapiens cyclin A/CDK2-associated ... 32 2.2
AF183187-1|AAG17468.1| 1230|Homo sapiens heart/fetal otoferlin p... 32 2.2
AF183186-1|AAG12992.1| 1307|Homo sapiens brain otoferlin short i... 32 2.2
AF183185-1|AAG12991.1| 1997|Homo sapiens brain otoferlin long is... 32 2.2
AF107403-1|AAD26117.1| 1230|Homo sapiens otoferlin protein. 32 2.2
AC093378-2|AAY15083.1| 1230|Homo sapiens unknown protein. 32 2.2
BC003380-1|AAH03380.1| 268|Homo sapiens acidic (leucine-rich) n... 30 8.9
AY057381-1|AAL25814.1| 266|Homo sapiens lecuine-rich acidic pro... 30 8.9
AL138795-4|CAI22808.1| 268|Homo sapiens acidic (leucine-rich) n... 30 8.9
AL138795-1|CAI22806.1| 220|Homo sapiens acidic (leucine-rich) n... 30 8.9
AK223469-1|BAD97189.1| 266|Homo sapiens acidic (leucine-rich) n... 30 8.9
AK095228-1|BAC04505.1| 218|Homo sapiens protein ( Homo sapiens ... 30 8.9
AK092672-1|BAC03942.1| 268|Homo sapiens mRNA. protein. 30 8.9
>BC007441-1|AAH07441.1| 410|Homo sapiens S-phase kinase-associated
protein 2 (p45) protein.
Length = 410
Score = 41.5 bits (93), Expect = 0.004
Identities = 34/123 (27%), Positives = 68/123 (55%), Gaps = 2/123 (1%)
Frame = +2
Query: 329 IVEQGRHLTSLNLKGVWVKDEHLPLMYQLIKNLTNLTALNIPYIA--NDEVLKYIGEHNK 502
I+ Q L +L+L+G+ + D P++ L KN +NL LN+ + ++ L+ +
Sbjct: 201 ILSQCSKLQNLSLEGLRLSD---PIVNTLAKN-SNLVRLNLSGCSGFSEFALQTLLSSCS 256
Query: 503 VLKLLDVSGETDITEIGIDAMLSGNPQLTQSLTVINIGMYGEENIDHTDVALLIRRLPNL 682
L L++S D TE + ++ +++++T +N+ Y +N+ +D++ L+RR PNL
Sbjct: 257 RLDELNLSWCFDFTEKHVQVAVA---HVSETITQLNLSGY-RKNLQKSDLSTLVRRCPNL 312
Query: 683 TNL 691
+L
Sbjct: 313 VHL 315
>BC001441-1|AAH01441.1| 410|Homo sapiens S-phase kinase-associated
protein 2 (p45) protein.
Length = 410
Score = 41.5 bits (93), Expect = 0.004
Identities = 34/123 (27%), Positives = 68/123 (55%), Gaps = 2/123 (1%)
Frame = +2
Query: 329 IVEQGRHLTSLNLKGVWVKDEHLPLMYQLIKNLTNLTALNIPYIA--NDEVLKYIGEHNK 502
I+ Q L +L+L+G+ + D P++ L KN +NL LN+ + ++ L+ +
Sbjct: 201 ILSQCSKLQNLSLEGLRLSD---PIVNTLAKN-SNLVRLNLSGCSGFSEFALQTLLSSCS 256
Query: 503 VLKLLDVSGETDITEIGIDAMLSGNPQLTQSLTVINIGMYGEENIDHTDVALLIRRLPNL 682
L L++S D TE + ++ +++++T +N+ Y +N+ +D++ L+RR PNL
Sbjct: 257 RLDELNLSWCFDFTEKHVQVAVA---HVSETITQLNLSGY-RKNLQKSDLSTLVRRCPNL 312
Query: 683 TNL 691
+L
Sbjct: 313 VHL 315
>AY029177-1|AAK31593.1| 424|Homo sapiens F-box protein SKP2
protein.
Length = 424
Score = 41.5 bits (93), Expect = 0.004
Identities = 34/123 (27%), Positives = 68/123 (55%), Gaps = 2/123 (1%)
Frame = +2
Query: 329 IVEQGRHLTSLNLKGVWVKDEHLPLMYQLIKNLTNLTALNIPYIA--NDEVLKYIGEHNK 502
I+ Q L +L+L+G+ + D P++ L KN +NL LN+ + ++ L+ +
Sbjct: 201 ILSQCSKLQNLSLEGLRLSD---PIVNTLAKN-SNLVRLNLSGCSGFSEFALQTLLSSCS 256
Query: 503 VLKLLDVSGETDITEIGIDAMLSGNPQLTQSLTVINIGMYGEENIDHTDVALLIRRLPNL 682
L L++S D TE + ++ +++++T +N+ Y +N+ +D++ L+RR PNL
Sbjct: 257 RLDELNLSWCFDFTEKHVQVAVA---HVSETITQLNLSGY-RKNLQKSDLSTLVRRCPNL 312
Query: 683 TNL 691
+L
Sbjct: 313 VHL 315
>AB050981-1|BAB87202.1| 442|Homo sapiens SKP2-like protein type
gamma protein.
Length = 442
Score = 41.5 bits (93), Expect = 0.004
Identities = 34/123 (27%), Positives = 68/123 (55%), Gaps = 2/123 (1%)
Frame = +2
Query: 329 IVEQGRHLTSLNLKGVWVKDEHLPLMYQLIKNLTNLTALNIPYIA--NDEVLKYIGEHNK 502
I+ Q L +L+L+G+ + D P++ L KN +NL LN+ + ++ L+ +
Sbjct: 201 ILSQCSKLQNLSLEGLRLSD---PIVNTLAKN-SNLVRLNLSGCSGFSEFALQTLLSSCS 256
Query: 503 VLKLLDVSGETDITEIGIDAMLSGNPQLTQSLTVINIGMYGEENIDHTDVALLIRRLPNL 682
L L++S D TE + ++ +++++T +N+ Y +N+ +D++ L+RR PNL
Sbjct: 257 RLDELNLSWCFDFTEKHVQVAVA---HVSETITQLNLSGY-RKNLQKSDLSTLVRRCPNL 312
Query: 683 TNL 691
+L
Sbjct: 313 VHL 315
>AB050980-1|BAB87201.1| 410|Homo sapiens SKP2-like protein type
beta protein.
Length = 410
Score = 41.5 bits (93), Expect = 0.004
Identities = 34/123 (27%), Positives = 68/123 (55%), Gaps = 2/123 (1%)
Frame = +2
Query: 329 IVEQGRHLTSLNLKGVWVKDEHLPLMYQLIKNLTNLTALNIPYIA--NDEVLKYIGEHNK 502
I+ Q L +L+L+G+ + D P++ L KN +NL LN+ + ++ L+ +
Sbjct: 201 ILSQCSKLQNLSLEGLRLSD---PIVNTLAKN-SNLVRLNLSGCSGFSEFALQTLLSSCS 256
Query: 503 VLKLLDVSGETDITEIGIDAMLSGNPQLTQSLTVINIGMYGEENIDHTDVALLIRRLPNL 682
L L++S D TE + ++ +++++T +N+ Y +N+ +D++ L+RR PNL
Sbjct: 257 RLDELNLSWCFDFTEKHVQVAVA---HVSETITQLNLSGY-RKNLQKSDLSTLVRRCPNL 312
Query: 683 TNL 691
+L
Sbjct: 313 VHL 315
>AB050979-1|BAB87200.1| 424|Homo sapiens SKP2-like protein type
alpha protein.
Length = 424
Score = 41.5 bits (93), Expect = 0.004
Identities = 34/123 (27%), Positives = 68/123 (55%), Gaps = 2/123 (1%)
Frame = +2
Query: 329 IVEQGRHLTSLNLKGVWVKDEHLPLMYQLIKNLTNLTALNIPYIA--NDEVLKYIGEHNK 502
I+ Q L +L+L+G+ + D P++ L KN +NL LN+ + ++ L+ +
Sbjct: 201 ILSQCSKLQNLSLEGLRLSD---PIVNTLAKN-SNLVRLNLSGCSGFSEFALQTLLSSCS 256
Query: 503 VLKLLDVSGETDITEIGIDAMLSGNPQLTQSLTVINIGMYGEENIDHTDVALLIRRLPNL 682
L L++S D TE + ++ +++++T +N+ Y +N+ +D++ L+RR PNL
Sbjct: 257 RLDELNLSWCFDFTEKHVQVAVA---HVSETITQLNLSGY-RKNLQKSDLSTLVRRCPNL 312
Query: 683 TNL 691
+L
Sbjct: 313 VHL 315
>U33761-1|AAC50242.1| 435|Homo sapiens cyclin A/CDK2-associated p45
protein.
Length = 435
Score = 32.3 bits (70), Expect = 2.2
Identities = 27/100 (27%), Positives = 52/100 (52%), Gaps = 2/100 (2%)
Frame = +2
Query: 398 PLMYQLIKNLTNLTALNIPYIANDEV--LKYIGEHNKVLKLLDVSGETDITEIGIDAMLS 571
P++ L KN +NL LN+P L+ L L++S + TE + ++
Sbjct: 232 PIVNTLAKN-SNLVRLNLPGCPGFPKFPLQTFLSSCPRLDELNLSWCFNFTEKHVQVAVA 290
Query: 572 GNPQLTQSLTVINIGMYGEENIDHTDVALLIRRLPNLTNL 691
+++++T +N+ Y +N+ +D++ L+RR PNL +L
Sbjct: 291 ---HVSETMTQLNLSGY-RKNLQKSDLSTLVRRCPNLVHL 326
>AF183187-1|AAG17468.1| 1230|Homo sapiens heart/fetal otoferlin
protein.
Length = 1230
Score = 32.3 bits (70), Expect = 2.2
Identities = 18/71 (25%), Positives = 35/71 (49%), Gaps = 5/71 (7%)
Frame = +2
Query: 578 PQLTQSLTVINIGMYGEENIDHTDVALLIRRLPNLTNLGSYSFVGKSISH--IYNTD--- 742
P Q L N+ +YGE + D +++ + + ++G F+G++ + + D
Sbjct: 258 PTWDQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAY 317
Query: 743 CPPNFKTKLQY 775
CPP F +L+Y
Sbjct: 318 CPPRFPPQLEY 328
>AF183186-1|AAG12992.1| 1307|Homo sapiens brain otoferlin short
isoform protein.
Length = 1307
Score = 32.3 bits (70), Expect = 2.2
Identities = 18/71 (25%), Positives = 35/71 (49%), Gaps = 5/71 (7%)
Frame = +2
Query: 578 PQLTQSLTVINIGMYGEENIDHTDVALLIRRLPNLTNLGSYSFVGKSISH--IYNTD--- 742
P Q L N+ +YGE + D +++ + + ++G F+G++ + + D
Sbjct: 315 PTWDQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAY 374
Query: 743 CPPNFKTKLQY 775
CPP F +L+Y
Sbjct: 375 CPPRFPPQLEY 385
>AF183185-1|AAG12991.1| 1997|Homo sapiens brain otoferlin long isoform
protein.
Length = 1997
Score = 32.3 bits (70), Expect = 2.2
Identities = 18/71 (25%), Positives = 35/71 (49%), Gaps = 5/71 (7%)
Frame = +2
Query: 578 PQLTQSLTVINIGMYGEENIDHTDVALLIRRLPNLTNLGSYSFVGKSISH--IYNTD--- 742
P Q L N+ +YGE + D +++ + + ++G F+G++ + + D
Sbjct: 1005 PTWDQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAY 1064
Query: 743 CPPNFKTKLQY 775
CPP F +L+Y
Sbjct: 1065 CPPRFPPQLEY 1075
>AF107403-1|AAD26117.1| 1230|Homo sapiens otoferlin protein.
Length = 1230
Score = 32.3 bits (70), Expect = 2.2
Identities = 18/71 (25%), Positives = 35/71 (49%), Gaps = 5/71 (7%)
Frame = +2
Query: 578 PQLTQSLTVINIGMYGEENIDHTDVALLIRRLPNLTNLGSYSFVGKSISH--IYNTD--- 742
P Q L N+ +YGE + D +++ + + ++G F+G++ + + D
Sbjct: 258 PTWDQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAY 317
Query: 743 CPPNFKTKLQY 775
CPP F +L+Y
Sbjct: 318 CPPRFPPQLEY 328
>AC093378-2|AAY15083.1| 1230|Homo sapiens unknown protein.
Length = 1230
Score = 32.3 bits (70), Expect = 2.2
Identities = 18/71 (25%), Positives = 35/71 (49%), Gaps = 5/71 (7%)
Frame = +2
Query: 578 PQLTQSLTVINIGMYGEENIDHTDVALLIRRLPNLTNLGSYSFVGKSISH--IYNTD--- 742
P Q L N+ +YGE + D +++ + + ++G F+G++ + + D
Sbjct: 258 PTWDQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAY 317
Query: 743 CPPNFKTKLQY 775
CPP F +L+Y
Sbjct: 318 CPPRFPPQLEY 328
>BC003380-1|AAH03380.1| 268|Homo sapiens acidic (leucine-rich)
nuclear phosphoprotein 32 family, member E protein.
Length = 268
Score = 30.3 bits (65), Expect = 8.9
Identities = 21/73 (28%), Positives = 35/73 (47%)
Frame = +2
Query: 320 IEIIVEQGRHLTSLNLKGVWVKDEHLPLMYQLIKNLTNLTALNIPYIANDEVLKYIGEHN 499
+E++ E+ +LT LNL G +KD Q +KNL +L N ++ + I E
Sbjct: 80 LEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDLFNCEITNLEDYRESIFELL 139
Query: 500 KVLKLLDVSGETD 538
+ + LD + D
Sbjct: 140 QQITYLDGFDQED 152
>AY057381-1|AAL25814.1| 266|Homo sapiens lecuine-rich acidic
protein-like protein protein.
Length = 266
Score = 30.3 bits (65), Expect = 8.9
Identities = 21/73 (28%), Positives = 35/73 (47%)
Frame = +2
Query: 320 IEIIVEQGRHLTSLNLKGVWVKDEHLPLMYQLIKNLTNLTALNIPYIANDEVLKYIGEHN 499
+E++ E+ +LT LNL G +KD Q +KNL +L N ++ + I E
Sbjct: 80 LEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDLFNCEITNLEDYRESIFELL 139
Query: 500 KVLKLLDVSGETD 538
+ + LD + D
Sbjct: 140 QQITYLDGFDQED 152
>AL138795-4|CAI22808.1| 268|Homo sapiens acidic (leucine-rich)
nuclear phosphoprotein 32 family, member E protein.
Length = 268
Score = 30.3 bits (65), Expect = 8.9
Identities = 21/73 (28%), Positives = 35/73 (47%)
Frame = +2
Query: 320 IEIIVEQGRHLTSLNLKGVWVKDEHLPLMYQLIKNLTNLTALNIPYIANDEVLKYIGEHN 499
+E++ E+ +LT LNL G +KD Q +KNL +L N ++ + I E
Sbjct: 80 LEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDLFNCEITNLEDYRESIFELL 139
Query: 500 KVLKLLDVSGETD 538
+ + LD + D
Sbjct: 140 QQITYLDGFDQED 152
>AL138795-1|CAI22806.1| 220|Homo sapiens acidic (leucine-rich)
nuclear phosphoprotein 32 family, member E protein.
Length = 220
Score = 30.3 bits (65), Expect = 8.9
Identities = 21/73 (28%), Positives = 35/73 (47%)
Frame = +2
Query: 320 IEIIVEQGRHLTSLNLKGVWVKDEHLPLMYQLIKNLTNLTALNIPYIANDEVLKYIGEHN 499
+E++ E+ +LT LNL G +KD Q +KNL +L N ++ + I E
Sbjct: 32 LEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDLFNCEITNLEDYRESIFELL 91
Query: 500 KVLKLLDVSGETD 538
+ + LD + D
Sbjct: 92 QQITYLDGFDQED 104
>AK223469-1|BAD97189.1| 266|Homo sapiens acidic (leucine-rich)
nuclear phosphoprotein 32 family, member E variant
protein.
Length = 266
Score = 30.3 bits (65), Expect = 8.9
Identities = 21/73 (28%), Positives = 35/73 (47%)
Frame = +2
Query: 320 IEIIVEQGRHLTSLNLKGVWVKDEHLPLMYQLIKNLTNLTALNIPYIANDEVLKYIGEHN 499
+E++ E+ +LT LNL G +KD Q +KNL +L N ++ + I E
Sbjct: 80 LEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDLFNCEITNLEDYRESIFELL 139
Query: 500 KVLKLLDVSGETD 538
+ + LD + D
Sbjct: 140 QQITYLDGFDQED 152
>AK095228-1|BAC04505.1| 218|Homo sapiens protein ( Homo sapiens
cDNA FLJ37909 fis, clone CTONG1000022, highly similar to
Mus musculus cerebellar postnatal development protein-1
(Cpd1) ).
Length = 218
Score = 30.3 bits (65), Expect = 8.9
Identities = 21/73 (28%), Positives = 35/73 (47%)
Frame = +2
Query: 320 IEIIVEQGRHLTSLNLKGVWVKDEHLPLMYQLIKNLTNLTALNIPYIANDEVLKYIGEHN 499
+E++ E+ +LT LNL G +KD Q +KNL +L N ++ + I E
Sbjct: 32 LEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDLFNCEITNLEDYRESIFELL 91
Query: 500 KVLKLLDVSGETD 538
+ + LD + D
Sbjct: 92 QQITYLDGFDQED 104
>AK092672-1|BAC03942.1| 268|Homo sapiens mRNA. protein.
Length = 268
Score = 30.3 bits (65), Expect = 8.9
Identities = 21/73 (28%), Positives = 35/73 (47%)
Frame = +2
Query: 320 IEIIVEQGRHLTSLNLKGVWVKDEHLPLMYQLIKNLTNLTALNIPYIANDEVLKYIGEHN 499
+E++ E+ +LT LNL G +KD Q +KNL +L N ++ + I E
Sbjct: 80 LEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDLFNCEITNLEDYRESIFELL 139
Query: 500 KVLKLLDVSGETD 538
+ + LD + D
Sbjct: 140 QQITYLDGFDQED 152
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 100,192,724
Number of Sequences: 237096
Number of extensions: 1905529
Number of successful extensions: 7033
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 6895
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7026
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10426655866
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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