Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P05_F_L07
(833 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9NR45 Cluster: Sialic acid synthase; n=39; Coelomata|R... 265 1e-69
UniRef50_Q9VG74 Cluster: CG5232-PA; n=4; Diptera|Rep: CG5232-PA ... 218 1e-55
UniRef50_Q07IS3 Cluster: N-acetylneuraminate synthase; n=1; Rhod... 161 1e-38
UniRef50_A6D0F9 Cluster: Sialic acid synthase; n=2; Gammaproteob... 152 9e-36
UniRef50_Q9RDX5 Cluster: N-acetylneuraminic acid condensing enzy... 152 1e-35
UniRef50_Q1IMQ8 Cluster: N-acetylneuraminate synthase; n=16; Bac... 151 2e-35
UniRef50_A7DQW3 Cluster: N-acylneuraminate-9-phosphate synthase;... 149 1e-34
UniRef50_Q58465 Cluster: Uncharacterized protein MJ1065; n=1; Me... 148 1e-34
UniRef50_Q74B32 Cluster: Polysaccharide biosynthesis protein, pu... 146 6e-34
UniRef50_A4FX91 Cluster: N-acylneuraminate-9-phosphate synthase;... 145 1e-33
UniRef50_A6L7H8 Cluster: Sialic acid synthase; n=1; Bacteroides ... 144 2e-33
UniRef50_UPI00015B984F Cluster: UPI00015B984F related cluster; n... 140 5e-32
UniRef50_Q3AZQ1 Cluster: N-acylneuraminate-9-phosphate synthase;... 140 5e-32
UniRef50_UPI0000D9DE3E Cluster: PREDICTED: similar to N-acetylne... 139 7e-32
UniRef50_Q04TT0 Cluster: N-acetyl neuraminic (Sialic) acid synth... 138 2e-31
UniRef50_A0NMM3 Cluster: N-acylneuraminate-9-phosphate synthase;... 136 5e-31
UniRef50_Q0M1E8 Cluster: N-acylneuraminate-9-phosphate synthase;... 134 2e-30
UniRef50_Q0FYM0 Cluster: N-acylneuraminate-9-phosphate synthase;... 134 3e-30
UniRef50_Q8A711 Cluster: Sialic acid synthase; n=1; Bacteroides ... 132 8e-30
UniRef50_A5MZ25 Cluster: Predicted polysaccharide biosynthesis p... 128 2e-28
UniRef50_Q3XXA4 Cluster: N-acetylneuraminate synthase; n=1; Ente... 123 6e-27
UniRef50_A2C5V5 Cluster: Sialic acid synthase; n=1; Prochlorococ... 123 6e-27
UniRef50_Q0IDR1 Cluster: N-acetylneuraminic acid condensing enzy... 121 3e-26
UniRef50_Q04TM5 Cluster: N-acetylneuraminic acid (Sialic acid) s... 120 3e-26
UniRef50_Q89HL9 Cluster: Blr5971 protein; n=1; Bradyrhizobium ja... 118 2e-25
UniRef50_Q8DDZ7 Cluster: Sialic acid synthase; n=5; Bacteria|Rep... 115 2e-24
UniRef50_Q893U6 Cluster: N-acetylneuraminate synthase; n=1; Clos... 115 2e-24
UniRef50_A7GGU3 Cluster: NeuB family protein; n=1; Clostridium b... 113 5e-24
UniRef50_A4AP54 Cluster: N-acetylneuraminate synthase; n=3; cell... 113 5e-24
UniRef50_Q8TJL5 Cluster: N-acetylneuraminic acid phosphate synth... 113 7e-24
UniRef50_Q9A4G6 Cluster: NeuB protein, putative; n=17; Bacteria|... 111 2e-23
UniRef50_A3PE56 Cluster: Sialic acid synthase; n=1; Prochlorococ... 110 4e-23
UniRef50_Q4VKA5 Cluster: NeuNAc condensing enzyme; n=54; cellula... 109 1e-22
UniRef50_A3V3D1 Cluster: Polysialic acid capsule biosynthesis pr... 108 1e-22
UniRef50_Q2Y4J1 Cluster: NeuB family member; n=5; cellular organ... 108 1e-22
UniRef50_Q89HJ8 Cluster: Blr5992 protein; n=2; Proteobacteria|Re... 107 3e-22
UniRef50_Q12JI6 Cluster: N-acetylneuraminic acid synthase-like p... 107 3e-22
UniRef50_A4MIF1 Cluster: N-acylneuraminate-9-phosphate synthase;... 107 3e-22
UniRef50_Q1GST3 Cluster: N-acylneuraminate-9-phosphate synthase;... 107 4e-22
UniRef50_Q46675 Cluster: NeuB protein; n=8; Bacteria|Rep: NeuB p... 106 6e-22
UniRef50_UPI0000384B44 Cluster: COG2089: Sialic acid synthase; n... 103 6e-21
UniRef50_Q7MPQ0 Cluster: Sialic acid synthase; n=3; Proteobacter... 103 6e-21
UniRef50_A1WSD6 Cluster: N-acylneuraminate-9-phosphate synthase;... 103 7e-21
UniRef50_Q97H26 Cluster: Sialic acid synthase; n=14; cellular or... 101 2e-20
UniRef50_Q5QWT8 Cluster: Sialic acid synthase; n=14; Bacteria|Re... 101 3e-20
UniRef50_Q93NQ2 Cluster: NnaB; n=7; Bacteria|Rep: NnaB - Escheri... 101 3e-20
UniRef50_Q73P39 Cluster: NeuB family protein; n=1; Treponema den... 100 9e-20
UniRef50_Q0A628 Cluster: N-acylneuraminate-9-phosphate synthase;... 99 2e-19
UniRef50_A4B2T9 Cluster: NeuB:Antifreeze-like protein; n=1; Alte... 98 3e-19
UniRef50_Q7NQV6 Cluster: N-acetylneuraminic acid synthase; n=7; ... 96 1e-18
UniRef50_Q30V22 Cluster: N-acylneuraminate-9-phosphate synthase;... 96 1e-18
UniRef50_A4U183 Cluster: N-acetylneuraminate synthase; n=1; Magn... 96 1e-18
UniRef50_A3Y8V9 Cluster: NeuB family protein; n=1; Marinomonas s... 95 2e-18
UniRef50_Q1PVV9 Cluster: Similarity to N-acetyl neuramic acid sy... 95 3e-18
UniRef50_P39625 Cluster: Spore coat polysaccharide biosynthesis ... 94 3e-18
UniRef50_A1RHT0 Cluster: N-acylneuraminate-9-phosphate synthase;... 93 8e-18
UniRef50_A4BEM9 Cluster: Sialic acid synthase; n=1; Reinekea sp.... 93 1e-17
UniRef50_A4U173 Cluster: NeuB; n=1; Magnetospirillum gryphiswald... 92 2e-17
UniRef50_Q5R082 Cluster: Sialic acid synthase; n=47; Bacteria|Re... 91 4e-17
UniRef50_Q04TP3 Cluster: N-acetylneuraminic acid (Sialic acid) s... 91 4e-17
UniRef50_Q11RF6 Cluster: N-acetylneuraminic acid synthetase; n=2... 89 1e-16
UniRef50_Q18EL3 Cluster: Sialic acid synthase; n=1; Haloquadratu... 89 1e-16
UniRef50_Q7VHQ5 Cluster: Sialic acid synthase; n=6; Helicobacter... 87 4e-16
UniRef50_Q726U8 Cluster: NeuB family protein; n=2; Desulfovibrio... 87 5e-16
UniRef50_Q2IZW6 Cluster: N-acetylneuraminate synthase; n=1; Rhod... 84 5e-15
UniRef50_A0LYV7 Cluster: N-acetylneuraminate synthase; n=1; Gram... 83 6e-15
UniRef50_A6W187 Cluster: N-acylneuraminate-9-phosphate synthase;... 82 1e-14
UniRef50_Q3B0R9 Cluster: N-acylneuraminate-9-phosphate synthase;... 82 2e-14
UniRef50_Q0P8U0 Cluster: Pse synthetase; n=14; Campylobacter|Rep... 81 3e-14
UniRef50_Q0YTS4 Cluster: N-acylneuraminate-9-phosphate synthase;... 81 4e-14
UniRef50_Q0AN71 Cluster: N-acetylneuraminate synthase; n=1; Mari... 80 8e-14
UniRef50_Q2N2P7 Cluster: NeuB; n=7; Proteobacteria|Rep: NeuB - A... 79 1e-13
UniRef50_A2BSE7 Cluster: Sialic acid synthase; n=1; Prochlorococ... 79 1e-13
UniRef50_Q2BI17 Cluster: N-acetylneuraminate synthase; n=4; Bact... 76 1e-12
UniRef50_A7DQU2 Cluster: N-acylneuraminate-9-phosphate synthase;... 73 7e-12
UniRef50_O83573 Cluster: Spore coat polysaccharide biosynthesis ... 67 6e-10
UniRef50_UPI0000E87B4B Cluster: putative N-acetyl neuramic acid ... 64 3e-09
UniRef50_Q2BJD7 Cluster: N-acetylneuraminic acid synthetase; n=1... 64 3e-09
UniRef50_A0LAB4 Cluster: N-acetylneuraminic acid synthase, N-ter... 64 5e-09
UniRef50_Q8EC83 Cluster: Polysaccharide biosynthesis related-pro... 63 7e-09
UniRef50_Q319P5 Cluster: Putative spore coat polysaccharide bios... 55 2e-06
UniRef50_Q2AHF7 Cluster: Antifreeze-like; n=1; Halothermothrix o... 52 2e-05
UniRef50_A5W0I0 Cluster: N-acetylneuraminic acid synthase, N-ter... 51 3e-05
UniRef50_Q9P0B2 Cluster: HSPC269; n=2; Homo sapiens|Rep: HSPC269... 50 1e-04
UniRef50_Q0IDQ4 Cluster: NeuB family protein; n=1; Synechococcus... 47 7e-04
UniRef50_A5IGD9 Cluster: Spore coat polysaccharide biosynthesis ... 47 7e-04
UniRef50_Q7NR94 Cluster: Probable spore coat polysaccharide bios... 42 0.019
UniRef50_UPI0000F219ED Cluster: PREDICTED: hypothetical protein;... 38 0.41
UniRef50_Q8RI47 Cluster: Tetratricopeptide repeat family protein... 34 3.8
UniRef50_Q5A950 Cluster: Sterol 3-beta-glucosyltransferase; n=2;... 34 5.1
UniRef50_Q7VQK1 Cluster: Survival protein SurA; n=1; Candidatus ... 33 6.7
UniRef50_Q54FM7 Cluster: Putative uncharacterized protein; n=1; ... 33 8.8
>UniRef50_Q9NR45 Cluster: Sialic acid synthase; n=39; Coelomata|Rep:
Sialic acid synthase - Homo sapiens (Human)
Length = 359
Score = 265 bits (649), Expect = 1e-69
Identities = 126/254 (49%), Positives = 159/254 (62%), Gaps = 1/254 (0%)
Frame = +1
Query: 64 VEVKITDDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKF 243
+E+++ +GG +PCFIIAE GQNHQGD GA C KFQK+ L KF
Sbjct: 3 LELELCPGRWVGGQHPCFIIAEIGQNHQGDLDVAKRMIRMAKECGADCAKFQKSELEFKF 62
Query: 244 TKKYLERPYDNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFL 423
+K LERPY + +SWGKTYGEHK HLEFS QYREL RYA+EVGI FTAS MD ++ +FL
Sbjct: 63 NRKALERPYTSKHSWGKTYGEHKRHLEFSHDQYRELQRYAEEVGIFFTASGMDEMAVEFL 122
Query: 424 VNLKVPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLL 603
L VPF K+GSGD+NN +L+ A K P++IS+GM +K +Y I+ + FC L
Sbjct: 123 HELNVPFFKVGSGDTNNFPYLEKTAKKGRPMVISSGMQSMDTMKQVYQIVKPLNPNFCFL 182
Query: 604 HCISAYPVPFEDCNLTVLQDYKNTF-DVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLD 780
C SAYP+ ED NL V+ +Y+ F D+P+GYSG E G HITLD
Sbjct: 183 QCTSAYPLQPEDVNLRVISEYQKLFPDIPIGYSGHETGIAISVAAVALGAKVLERHITLD 242
Query: 781 KSMKGTDHVCSLTP 822
K+ KG+DH SL P
Sbjct: 243 KTWKGSDHSASLEP 256
>UniRef50_Q9VG74 Cluster: CG5232-PA; n=4; Diptera|Rep: CG5232-PA -
Drosophila melanogaster (Fruit fly)
Length = 372
Score = 218 bits (533), Expect = 1e-55
Identities = 110/238 (46%), Positives = 143/238 (60%), Gaps = 2/238 (0%)
Frame = +1
Query: 115 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGK 294
+IIAE GQNHQG G CVKFQK+ L KFT+ L+R Y + ++WGK
Sbjct: 16 YIIAEIGQNHQGCVETAKKMIWEAKKAGCHCVKFQKSDLPAKFTRSALDREYISDHAWGK 75
Query: 295 TYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNN 474
TYGEHK +LEFS QY +L + +E+ + FTASAMD S +FL L VPFIKIGSGD+NN
Sbjct: 76 TYGEHKEYLEFSKDQYLQLQAHCKELNVDFTASAMDERSLEFLSALNVPFIKIGSGDANN 135
Query: 475 LLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQ-FCLLHCISAYPVPFEDCNLT 651
LK AA+ +PL+ISTGM V+ I + K+ + L+HC+S+YP +DC+L
Sbjct: 136 FPLLKKAANLNLPLVISTGMQTMQTVERIVQTMRESGKEDYALMHCVSSYPTDPKDCSLQ 195
Query: 652 VLQDYKNTF-DVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTDHVCSLTP 822
++ + F +V +GYSG ELG H TLDKS KG+DH CSL P
Sbjct: 196 LISVLRTRFPNVAIGYSGHELGVIISQAAVLLGARIVERHFTLDKSQKGSDHRCSLEP 253
>UniRef50_Q07IS3 Cluster: N-acetylneuraminate synthase; n=1;
Rhodopseudomonas palustris BisA53|Rep:
N-acetylneuraminate synthase - Rhodopseudomonas
palustris (strain BisA53)
Length = 357
Score = 161 bits (392), Expect = 1e-38
Identities = 85/240 (35%), Positives = 121/240 (50%), Gaps = 1/240 (0%)
Frame = +1
Query: 106 NPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNS 285
NP F+IAE G NHQGD GA VK QK FT + + YD+ N+
Sbjct: 16 NPSFVIAEVGHNHQGDIEKCKAIFKAAKEAGADAVKIQKRDNRALFTAEMYDSHYDSENA 75
Query: 286 WGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGD 465
+ TYG H+ LEF+ QY EL Y +++ ILF ++A D S + L + +P KI SGD
Sbjct: 76 YAHTYGTHRECLEFNREQYLELKEYCKQLDILFFSTAFDEPSAELLEEIDMPGFKIASGD 135
Query: 466 SNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVPFEDCN 645
N LK AS P+I+STG + Y+ I ++ C++ C S YP P E+ N
Sbjct: 136 LVNTPLLKKVASYGKPIIVSTGGGTLADARLAYETIMPINRNLCIMQCTSGYPPPHEELN 195
Query: 646 LTVLQDYKNTF-DVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTDHVCSLTP 822
L V++ ++ F D+ +G+S + G H TL+++ KGTD SL P
Sbjct: 196 LRVIETFRREFPDIVIGFSSHDSGIAMPLVGYMLGARVFEKHFTLNRTWKGTDQAFSLEP 255
>UniRef50_A6D0F9 Cluster: Sialic acid synthase; n=2;
Gammaproteobacteria|Rep: Sialic acid synthase - Vibrio
shilonii AK1
Length = 751
Score = 152 bits (369), Expect = 9e-36
Identities = 86/248 (34%), Positives = 116/248 (46%), Gaps = 1/248 (0%)
Frame = +1
Query: 91 RIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPY 270
+IG P FIIAE G NH G GA CVKFQ + + + +
Sbjct: 123 KIGDQEPSFIIAEIGNNHNGSLELAKELVDLAKAAGADCVKFQMRDMASMYNNEGDDD-- 180
Query: 271 DNPNSWGKTYG-EHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFI 447
D G Y + + D ++ E+F Y ++ IL + D S D L + V
Sbjct: 181 DASQDLGAQYVLDLLKRFQLCDEEFVEIFEYCKQKEILALCTPFDEASADKLEKIGVAGF 240
Query: 448 KIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPV 627
K+ S D N LKY A+KK+PLI+STGM + + + +++ + F LLHC S YP
Sbjct: 241 KVASADLTNHRLLKYLAAKKVPLILSTGMSVEQEIISAVELLEKESASFALLHCNSTYPA 300
Query: 628 PFEDCNLTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTDHV 807
PF+D NLT L+ K+ VGYSG E G H T+DKSM+G DH
Sbjct: 301 PFKDVNLTYLKRLKSLGRTVVGYSGHERGYAIPIASIPLGAKIVEKHFTIDKSMEGNDHK 360
Query: 808 CSLTPSXF 831
SL P F
Sbjct: 361 VSLLPDEF 368
>UniRef50_Q9RDX5 Cluster: N-acetylneuraminic acid condensing enzyme;
n=6; Bacteria|Rep: N-acetylneuraminic acid condensing
enzyme - Legionella pneumophila
Length = 338
Score = 152 bits (368), Expect = 1e-35
Identities = 91/244 (37%), Positives = 121/244 (49%), Gaps = 7/244 (2%)
Frame = +1
Query: 112 CFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERP-YDNPNS- 285
CFIIAEAG NH GD GA VKFQ T + K +E+ Y N+
Sbjct: 3 CFIIAEAGVNHNGDLQLAKELVYAAKESGADAVKFQ-TFKADTLVNKTVEKAEYQKNNAP 61
Query: 286 WGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGD 465
T E LE S+ + L A +GI F ++ D S DFL++L V +KI SG+
Sbjct: 62 ESSTQYEMLKALELSEEDHYLLSELANSLGIEFMSTGFDEQSIDFLISLGVKRLKIPSGE 121
Query: 466 SNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDII-----SSDHKQFCLLHCISAYPVP 630
N+ +L++ ASKK+PLIISTGM D V+ D + +S LLHC S YP
Sbjct: 122 ITNVPYLQHCASKKLPLIISTGMCDLQEVRVAIDTVKPYYGNSLSDYLVLLHCTSNYPAS 181
Query: 631 FEDCNLTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTDHVC 810
++D NL +Q + F +PVGYS LG H T+DKS+ G DH+
Sbjct: 182 YQDVNLKAMQTLADEFQLPVGYSDHTLGILVPTLAVGMGACVIEKHFTMDKSLPGPDHLA 241
Query: 811 SLTP 822
S+ P
Sbjct: 242 SMDP 245
>UniRef50_Q1IMQ8 Cluster: N-acetylneuraminate synthase; n=16;
Bacteria|Rep: N-acetylneuraminate synthase -
Acidobacteria bacterium (strain Ellin345)
Length = 300
Score = 151 bits (367), Expect = 2e-35
Identities = 82/244 (33%), Positives = 120/244 (49%)
Frame = +1
Query: 94 IGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYD 273
+G + PC++IAE G NH GD G VKFQK + +T L +P +
Sbjct: 20 VGKDQPCYVIAEIGINHNGDMDIAKRLISVAVGAGCDAVKFQKRTIDVVYTAAELAKPRE 79
Query: 274 NPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKI 453
NP +G T G+ K LEF +++E+ RY +EV + + ASA D S DF+ VP KI
Sbjct: 80 NP--FGATNGDLKRGLEFGLEEFKEIDRYCREVRMPWFASAWDEASVDFIAQFDVPCFKI 137
Query: 454 GSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVPF 633
S + L++ + P+++STGM + D++ D+ LL S YP +
Sbjct: 138 ASASLTDDNLLRHTRATGKPVMLSTGMSTVEQIDHAVDVLGKDN--LILLQACSTYPAYY 195
Query: 634 EDCNLTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTDHVCS 813
E+ NL + + + VPVGYSG E G HITLD++M G+D S
Sbjct: 196 EELNLKAIHTLMDRYGVPVGYSGHETGLPASIAAAAMGACVLERHITLDRAMWGSDQAAS 255
Query: 814 LTPS 825
L P+
Sbjct: 256 LEPN 259
>UniRef50_A7DQW3 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep:
N-acylneuraminate-9-phosphate synthase - Candidatus
Nitrosopumilus maritimus SCM1
Length = 349
Score = 149 bits (360), Expect = 1e-34
Identities = 85/248 (34%), Positives = 115/248 (46%), Gaps = 1/248 (0%)
Frame = +1
Query: 91 RIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPY 270
RI P +IIAE G NH G+ GA+ VKFQK L + + + L+ P
Sbjct: 14 RISTKEPAYIIAEIGINHNGNITTAKKLIDVAVDAGANAVKFQKRSLNDIYREDVLKDP- 72
Query: 271 DNPNSWG-KTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFI 447
N S G + + + +EF D Y+EL Y +E I F + D+ S +FL +P
Sbjct: 73 -NIESQGLEILLDVLNEVEFDDDAYKELTEYCKEKHITFLCTPWDIPSVEFLEKFDLPAY 131
Query: 448 KIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPV 627
KI S D N + PLI+STGM + ++ + + +F LLHC S YP
Sbjct: 132 KIASADMTNFPLISSLIQTGKPLIVSTGMSNMNEIEKTVSFMKEKNAKFALLHCNSTYPA 191
Query: 628 PFEDCNLTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTDHV 807
P E NL ++ K F V +GYSG E G HITLDK+M+G D
Sbjct: 192 PVETLNLELISLLKEKFQVLIGYSGHEPGIVSTLAAVMLGAIIVERHITLDKTMEGLDQA 251
Query: 808 CSLTPSXF 831
SL P F
Sbjct: 252 ASLEPDEF 259
>UniRef50_Q58465 Cluster: Uncharacterized protein MJ1065; n=1;
Methanocaldococcus jannaschii|Rep: Uncharacterized
protein MJ1065 - Methanococcus jannaschii
Length = 337
Score = 148 bits (359), Expect = 1e-34
Identities = 88/258 (34%), Positives = 124/258 (48%), Gaps = 1/258 (0%)
Frame = +1
Query: 61 MVEVKITDDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEK 240
M ++KI D +G P FIIAE G NH GD GA +KFQ +
Sbjct: 1 MEKIKIGDRY-VGKGEPTFIIAEGGLNHNGDIDIGKELVKEAKKCGADAIKFQSYHTEDF 59
Query: 241 FTKKYLERPYDNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDF 420
+KK Y E LE S+ ++ EL YA+++GI+F ++ +D+ D
Sbjct: 60 ISKK-------------SEYYELFKSLELSEEEFYELKEYAEKIGIMFISTPLDLKYVDI 106
Query: 421 LVNLKVPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDH-KQFC 597
L + VP KI SGD L+ A P+I+STGM D + ++ ++ +
Sbjct: 107 LNKMNVPAFKIASGDLTFYPLLEKVAKTGKPVILSTGMSDIGEIWEAVKVLENNGCRDII 166
Query: 598 LLHCISAYPVPFEDCNLTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITL 777
LLHCIS+YP P+ED NL ++ K+ F++PVGYS LG H TL
Sbjct: 167 LLHCISSYPTPYEDVNLNAIKTLKSIFNIPVGYSDHTLGILAPVVSVALGADVIEKHFTL 226
Query: 778 DKSMKGTDHVCSLTPSXF 831
DK+M+G DH S P F
Sbjct: 227 DKNMEGPDHALSADPEEF 244
>UniRef50_Q74B32 Cluster: Polysaccharide biosynthesis protein,
putative; n=1; Geobacter sulfurreducens|Rep:
Polysaccharide biosynthesis protein, putative -
Geobacter sulfurreducens
Length = 350
Score = 146 bits (354), Expect = 6e-34
Identities = 83/251 (33%), Positives = 122/251 (48%), Gaps = 4/251 (1%)
Frame = +1
Query: 85 DIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLER 264
++ +G NP ++IAE G NH GD GA VKFQ ++ ER
Sbjct: 8 NVPVGAENPPYVIAEIGSNHNGDMNLCRQLIDAAAEAGAHAVKFQSWTENSLIAREEYER 67
Query: 265 --PY-DNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLK 435
Y D +G K++ + + Q+RE Y +E GI F ++ D L +L
Sbjct: 68 NTEYSDKKRHFGSLRDMVKTY-QLTTDQHREAHAYCRERGIAFCSTPFSPEEADLLESLD 126
Query: 436 VPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSD-HKQFCLLHCI 612
VPF KI S D +L FLKY A K+ P+++STGM ++ + + ++ + Q LLHC+
Sbjct: 127 VPFFKIASMDIVHLPFLKYVARKRRPMLLSTGMATLAEIEAAVETVRAEGNDQVVLLHCV 186
Query: 613 SAYPVPFEDCNLTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMK 792
S YP +E +L + + FDVPVG+S +GT H TLD+ M+
Sbjct: 187 SIYPPDYEMIHLRNMATLQQAFDVPVGFSDHTMGTAIPLAAIALGACVIEKHFTLDQDME 246
Query: 793 GTDHVCSLTPS 825
G DH S TP+
Sbjct: 247 GWDHAISATPT 257
>UniRef50_A4FX91 Cluster: N-acylneuraminate-9-phosphate synthase;
n=5; cellular organisms|Rep:
N-acylneuraminate-9-phosphate synthase - Methanococcus
maripaludis
Length = 348
Score = 145 bits (352), Expect = 1e-33
Identities = 84/245 (34%), Positives = 118/245 (48%), Gaps = 3/245 (1%)
Frame = +1
Query: 100 GNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNP 279
G FIIAEAG NH G G VKFQ T+ + Y
Sbjct: 11 GLKNAFIIAEAGVNHNGSLELAKKLIDVAFEAGVDAVKFQTFKTENVVTENAEKAEYQIQ 70
Query: 280 NSWGKTYGEHK--SHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKI 453
N+ ++ +++ LE S+ + L+ Y QE GILF ++ D S DFL +L VP KI
Sbjct: 71 NTGVESESQYEMIKKLELSEKDFERLYNYCQEKGILFLSTPFDFESADFLDDL-VPLFKI 129
Query: 454 GSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVK-TIYDIISSDHKQFCLLHCISAYPVP 630
S D NN+ FLK+ A KK P+IISTGM ++ + + ++ + + LLHC+++YP
Sbjct: 130 SSTDLNNIPFLKHIAKKKKPVIISTGMGTLCEIEEAVTALKNAGNHEIMLLHCVTSYPAK 189
Query: 631 FEDCNLTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTDHVC 810
E NL V+ +N F + VG+S LG H TLD + G DH
Sbjct: 190 DESLNLNVIHTLRNAFKLDVGFSDHSLGIYASIAAVSMGATIIEKHFTLDNELPGPDHKA 249
Query: 811 SLTPS 825
SL P+
Sbjct: 250 SLNPT 254
>UniRef50_A6L7H8 Cluster: Sialic acid synthase; n=1; Bacteroides
vulgatus ATCC 8482|Rep: Sialic acid synthase -
Bacteroides vulgatus (strain ATCC 8482 / DSM 1447 / NCTC
11154)
Length = 334
Score = 144 bits (349), Expect = 2e-33
Identities = 87/243 (35%), Positives = 114/243 (46%), Gaps = 4/243 (1%)
Frame = +1
Query: 106 NPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERP-YDNPN 282
N +IIAEAG NH G GA VKFQ T EK + E Y N
Sbjct: 3 NHVYIIAEAGVNHNGRLDLALQLCNAAKDAGADAVKFQ-TWKTEKIVTRNAELAVYQENN 61
Query: 283 SWGKTYGEHK--SHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIG 456
KT + K LE S + + + E+GI F ++ ++ S DFL N +PFIK+G
Sbjct: 62 ISDKTKSQFKMLKELELSYDNFEVVKNHCDEIGIQFLSTPDEIDSLDFLCNFNLPFIKLG 121
Query: 457 SGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIY-DIISSDHKQFCLLHCISAYPVPF 633
SGD N+ FL+ S+ I +++STGM V+ Y +I + K LLHC + YP P
Sbjct: 122 SGDVTNIPFLRLVGSRHIDVVLSTGMSYLGDVEIAYRTLIEAGAKSVSLLHCTTNYPCPM 181
Query: 634 EDCNLTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTDHVCS 813
+ NL +Q K+ F VGYS +G H TLDK M G DH S
Sbjct: 182 HEVNLRAIQTLKDAFHCSVGYSDHTMGVEVPVAAVAMGAEIIEKHFTLDKEMDGPDHKAS 241
Query: 814 LTP 822
L P
Sbjct: 242 LNP 244
>UniRef50_UPI00015B984F Cluster: UPI00015B984F related cluster; n=1;
unknown|Rep: UPI00015B984F UniRef100 entry - unknown
Length = 361
Score = 140 bits (338), Expect = 5e-32
Identities = 79/245 (32%), Positives = 113/245 (46%), Gaps = 2/245 (0%)
Frame = +1
Query: 94 IGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYD 273
IG + CF+IAEAG NH GD GA +KFQ + + Y
Sbjct: 23 IGNDGRCFVIAEAGVNHNGDVAMAHRLIDVAAAAGADAIKFQTFNAETLVDRSARKAAYQ 82
Query: 274 NPNSWGKTYG-EHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIK 450
N+ ++ E LE YR L +A + GI ++ D S DFL L VP K
Sbjct: 83 VTNTGSESSQFEMLRSLELPAQAYRALQDHAGQAGIALISTPFDEASVDFLATLGVPAYK 142
Query: 451 IGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVK-TIYDIISSDHKQFCLLHCISAYPV 627
+ SGD N L+ A+K P+IISTGM + ++ + + ++ ++ C L C S+YP
Sbjct: 143 VSSGDLTNHFLLEAVAAKGKPVIISTGMANLADIEGALACLRTAGAREVCALQCTSSYPA 202
Query: 628 PFEDCNLTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTDHV 807
P + NL + + F +P+GYS LG H+TLD+S+ G DH
Sbjct: 203 PPDQINLRTIATMRAAFGIPIGYSDHTLGIPVAIAAATLGAAVIEKHVTLDRSLLGPDHS 262
Query: 808 CSLTP 822
SL P
Sbjct: 263 ASLVP 267
>UniRef50_Q3AZQ1 Cluster: N-acylneuraminate-9-phosphate synthase;
n=17; Bacteria|Rep: N-acylneuraminate-9-phosphate
synthase - Synechococcus sp. (strain CC9902)
Length = 762
Score = 140 bits (338), Expect = 5e-32
Identities = 81/248 (32%), Positives = 113/248 (45%), Gaps = 2/248 (0%)
Frame = +1
Query: 94 IGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYD 273
IG +PCF+IAE G NH GD GA C KFQ +G+ ++ + D
Sbjct: 128 IGAEHPCFVIAEIGNNHNGDINTALQLIDAAHAAGADCAKFQMRDMGQLYSNS--GKSSD 185
Query: 274 NPNSWGKTYG-EHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIK 450
+ G Y + + SD + F Y+ G++ + D S L + K
Sbjct: 186 MASDLGTQYTLDLLERFQLSDDELFHCFDYSASKGLVPLCTPWDQTSLQKLNQWGMEGFK 245
Query: 451 IGSGD-SNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPV 627
+ S D +N+ L + AA+ K PLI STGM + +++ + + LLHC S YP
Sbjct: 246 VASADFTNHALITQLAATGK-PLICSTGMASELEIRSGIRHLQKAGANYVLLHCNSTYPT 304
Query: 628 PFEDCNLTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTDHV 807
PF+D NL L+ + D PVGYSG E G HITLD+ M+G DH
Sbjct: 305 PFKDVNLRYLERLRELADAPVGYSGHERGIEIPLAAAALGAVVIEKHITLDRGMEGNDHK 364
Query: 808 CSLTPSXF 831
SL P F
Sbjct: 365 VSLLPDEF 372
>UniRef50_UPI0000D9DE3E Cluster: PREDICTED: similar to
N-acetylneuraminic acid phosphate synthase; n=1; Macaca
mulatta|Rep: PREDICTED: similar to N-acetylneuraminic
acid phosphate synthase - Macaca mulatta
Length = 274
Score = 139 bits (337), Expect = 7e-32
Identities = 65/113 (57%), Positives = 77/113 (68%)
Frame = +1
Query: 64 VEVKITDDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKF 243
+E+++ +GG +PCFIIAE GQNHQGD GA C KFQK+ L KF
Sbjct: 3 LELELCPGRWVGGQHPCFIIAEIGQNHQGDLDVAKRMIRMAKECGADCAKFQKSELEFKF 62
Query: 244 TKKYLERPYDNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMD 402
+K LERPY + +SWGKTYGEHK HLEF+ QYREL RYA+EVGI FTAS MD
Sbjct: 63 NRKALERPYTSKHSWGKTYGEHKRHLEFNHDQYRELQRYAEEVGIFFTASGMD 115
Score = 51.2 bits (117), Expect = 3e-05
Identities = 23/56 (41%), Positives = 30/56 (53%), Gaps = 1/56 (1%)
Frame = +1
Query: 658 QDYKNTF-DVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTDHVCSLTP 822
++Y+ F D+P+GYSG E G HITLDK+ KG+DH SL P
Sbjct: 116 EEYQKLFPDIPIGYSGHETGIAISVAAVALGAKVLERHITLDKTWKGSDHSASLEP 171
>UniRef50_Q04TT0 Cluster: N-acetyl neuraminic (Sialic) acid
synthetase; n=4; Leptospira|Rep: N-acetyl neuraminic
(Sialic) acid synthetase - Leptospira borgpetersenii
serovar Hardjo-bovis (strain JB197)
Length = 332
Score = 138 bits (333), Expect = 2e-31
Identities = 77/250 (30%), Positives = 121/250 (48%), Gaps = 1/250 (0%)
Frame = +1
Query: 76 ITDDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKY 255
I ++ +G +P ++AE G NH D GA VKFQ T+++
Sbjct: 9 IASELYVGSESPPIVVAEIGLNHNNDEEIGKKTIAAAKKAGAQVVKFQSYV-----TEEF 63
Query: 256 LERPYDNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLK 435
++ NP++ K + E S+T +R+ + A++ G+ F ++ + + S L++LK
Sbjct: 64 ID--VHNPDA--KILVDIFKKYELSETMHRKFQKTAEDEGLFFFSTPLCVNSLHLLLSLK 119
Query: 436 VPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHK-QFCLLHCI 612
VP IKI SGD N L A K+P+I+S+G D V + + + CLLHC+
Sbjct: 120 VPAIKIASGDITNKTLLLETAKSKLPVILSSGAADFFEVNRAISFLEKEGTDKLCLLHCV 179
Query: 613 SAYPVPFEDCNLTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMK 792
S YP P E NL V++ +KN + PVG+S +G H TLD+++
Sbjct: 180 SLYPTPPEKANLKVVETFKNLYPFPVGFSDHTIGNIAASIAVSLGACMIEKHFTLDRNLD 239
Query: 793 GTDHVCSLTP 822
G DH S P
Sbjct: 240 GPDHGISANP 249
>UniRef50_A0NMM3 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Stappia aggregata IAM 12614|Rep:
N-acylneuraminate-9-phosphate synthase - Stappia
aggregata IAM 12614
Length = 287
Score = 136 bits (330), Expect = 5e-31
Identities = 81/236 (34%), Positives = 115/236 (48%), Gaps = 2/236 (0%)
Frame = +1
Query: 115 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGK 294
++IAE G NH GD G VKFQK + ++ + L RP +N +G
Sbjct: 8 YVIAEIGINHNGDIDQALEMIRKSKEAGCDAVKFQKRTVDVVYSAEELARPRENV--FGT 65
Query: 295 TYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNN 474
T G+ K LEF Y + + +E+GI + AS D S DFL++ P+IK+ S +
Sbjct: 66 TNGDLKRGLEFGKADYDRIDKLCKELGIDWFASPWDEGSVDFLLDYDTPYIKVASAMVTD 125
Query: 475 LLFLKYAASKKIPLIISTGMVDKTAVKTIYDIIS-SDHKQFCLLHCISAYPVPFEDCNLT 651
FL+Y A PL++STGM D VK+ D+I S + CL HC S YP ++ NL
Sbjct: 126 RDFLEYCARSGRPLLVSTGMSDMAMVKSFVDVIERSGGEIACLYHCTSTYPTRDDEINLR 185
Query: 652 VLQDYKNTF-DVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTDHVCSL 816
+ K F + +G+SG E G H+TLD+S G+D SL
Sbjct: 186 GISTLKEAFPHLKIGFSGHEEGILPSVCAAALGACSIERHVTLDRSDWGSDQKASL 241
>UniRef50_Q0M1E8 Cluster: N-acylneuraminate-9-phosphate synthase;
n=2; Bacteria|Rep: N-acylneuraminate-9-phosphate
synthase - Caulobacter sp. K31
Length = 310
Score = 134 bits (325), Expect = 2e-30
Identities = 76/236 (32%), Positives = 109/236 (46%)
Frame = +1
Query: 115 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGK 294
F+IAE G NH GD G VKFQK + +T + L +P +P WG
Sbjct: 34 FVIAEIGINHNGDLEITKQLIRAARDAGCDAVKFQKRTIDIVYTPEVLAQPRQSP--WGD 91
Query: 295 TYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNN 474
T K LEF +Y + Y +E+G+ + ASA D+ S FL +P+ KI S +
Sbjct: 92 TQRAQKEGLEFGKAEYDVIDAYCRELGLAWFASAWDVPSQTFLAAYDLPYNKIASAMLTH 151
Query: 475 LLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVPFEDCNLTV 654
++ A++ + STGM + T +I+ + F L+H +S YP P D NL
Sbjct: 152 RPLIEAVAAEGKLVFASTGMCTFEQIDTAVEILRAAACPFVLMHTVSTYPTPPADLNLLT 211
Query: 655 LQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTDHVCSLTP 822
+ + + PVGYSG E HITLD++M G+D SL P
Sbjct: 212 IDTLRRRYGAPVGYSGHESSVEPSLVAAMLGAVAIERHITLDRTMYGSDQSASLEP 267
>UniRef50_Q0FYM0 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Fulvimarina pelagi HTCC2506|Rep:
N-acylneuraminate-9-phosphate synthase - Fulvimarina
pelagi HTCC2506
Length = 347
Score = 134 bits (323), Expect = 3e-30
Identities = 82/241 (34%), Positives = 109/241 (45%), Gaps = 2/241 (0%)
Frame = +1
Query: 106 NPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNS 285
N F++AEAG NH G GA +KFQ T + Y N
Sbjct: 13 NWVFVVAEAGVNHNGSIERALDMVEAAARAGADAIKFQTFRAAGLVTANAEKAAYQKRND 72
Query: 286 WGKT-YGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSG 462
T E S LE S++Q+R + + VGI F ++ D S DFL +L V KI SG
Sbjct: 73 GIDTNQAEMLSALELSESQWRTIKDHCSMVGISFLSTPFDEDSADFLESLGVEAFKISSG 132
Query: 463 DSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDII-SSDHKQFCLLHCISAYPVPFED 639
D +L FL++ A K P+IISTGM + ++ D I ++ +LHC+S YP
Sbjct: 133 DLTHLAFLQHVARKGRPMIISTGMANLADIEEAVDAIEAAGSPPLAILHCVSDYPADPAS 192
Query: 640 CNLTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTDHVCSLT 819
NL + F PVG+S LG H TLDKS+ G DH+ SL
Sbjct: 193 SNLMAIPTLAAAFRRPVGWSDHTLGEATSLASIPLASKMIEKHFTLDKSLPGPDHIASLE 252
Query: 820 P 822
P
Sbjct: 253 P 253
>UniRef50_Q8A711 Cluster: Sialic acid synthase; n=1; Bacteroides
thetaiotaomicron|Rep: Sialic acid synthase - Bacteroides
thetaiotaomicron
Length = 346
Score = 132 bits (320), Expect = 8e-30
Identities = 77/250 (30%), Positives = 116/250 (46%), Gaps = 14/250 (5%)
Frame = +1
Query: 115 FIIAEAGQNHQGDXXXXXXXXXXXX-----------XXGASCVKFQKTCLGEKFTKKYLE 261
+II E GQNH G + VK K L E+ +
Sbjct: 5 YIIGEIGQNHNGSVDLAKLIIELISRPVHEDVFGMDFMPMNAVKMTKRDLSEELAVSQMN 64
Query: 262 RPYDNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVP 441
+ YDNPNS+G+TYGEH++ LE D + E+++YA+ +G+ F + L
Sbjct: 65 QIYDNPNSFGRTYGEHRAFLELDDQAHFEIYKYAKSLGLDFIETLCAKGCLSLLKLFTPD 124
Query: 442 FIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAY 621
+K+ S D NL L+ A IP+I+STGM + + D+I+ H +LHC+S Y
Sbjct: 125 RLKVASRDLTNLPLLEALAETHIPIILSTGMAGQRELDNALDVITRYHSNIAILHCVSQY 184
Query: 622 PVPFEDCNL---TVLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMK 792
P + NL T L+ + N F+ +G+S +G H+T+D+ MK
Sbjct: 185 PTHPNNLNLRTITYLKKHYNKFE--IGFSDHTIGISAATAAVAMGAEIIEKHVTIDRHMK 242
Query: 793 GTDHVCSLTP 822
GTD + SL P
Sbjct: 243 GTDQLGSLGP 252
>UniRef50_A5MZ25 Cluster: Predicted polysaccharide biosynthesis
protein; n=1; Clostridium kluyveri DSM 555|Rep:
Predicted polysaccharide biosynthesis protein -
Clostridium kluyveri DSM 555
Length = 335
Score = 128 bits (309), Expect = 2e-28
Identities = 79/255 (30%), Positives = 118/255 (46%), Gaps = 1/255 (0%)
Frame = +1
Query: 61 MVEVKITDDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEK 240
M ++KI + I IG +PCFIIAEAG NH GD GA+ VKFQ +
Sbjct: 1 MNDIKIGNKI-IGNTHPCFIIAEAGSNHNGDIKQAKELVDIAVEAGANAVKFQTFTADKL 59
Query: 241 FTKKYLERPYDNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDF 420
F+K + N K + EF ++E+ Y + GI+F + + D
Sbjct: 60 FSKNH------PANKIVKNF-------EFKLEWHKEMKEYCDKKGIMFITTPFQKDAVDL 106
Query: 421 LVNLKVPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQ-FC 597
L L + KI SGD + L Y ++ P+I+++GM VK ++ I + +
Sbjct: 107 LEKLNIEGYKIASGDMDYYPLLDYISNTGKPIILASGMAYMDEVKEAFNRIKNGKTEDIA 166
Query: 598 LLHCISAYPVPFEDCNLTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITL 777
+LHC+S YP ED NL +Q K F+VPVG+S +G H T+
Sbjct: 167 ILHCVSNYPPKDEDINLKAIQTIKEEFNVPVGFSDHSMGITVPIAAVALGANIIEKHFTI 226
Query: 778 DKSMKGTDHVCSLTP 822
+ ++G DH +L P
Sbjct: 227 SRKLEGMDHFYALEP 241
>UniRef50_Q3XXA4 Cluster: N-acetylneuraminate synthase; n=1;
Enterococcus faecium DO|Rep: N-acetylneuraminate
synthase - Enterococcus faecium DO
Length = 335
Score = 123 bits (296), Expect = 6e-27
Identities = 79/240 (32%), Positives = 101/240 (42%), Gaps = 1/240 (0%)
Frame = +1
Query: 115 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPN-SWG 291
++IAE G NH G GA+ VKFQ + +KK Y N
Sbjct: 7 YVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKTNKLVSKKAPMAKYQKDNLKED 66
Query: 292 KTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSN 471
+ E LE S + + + Y + I F ++ D S DFL + V KIGSGD
Sbjct: 67 SSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFDEESADFLKQIGVQGFKIGSGDLT 126
Query: 472 NLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVPFEDCNLT 651
NL FL+ +P+++STGM D V D +LHC S YP ED NL
Sbjct: 127 NLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFID--SPVTILHCTSNYPASSEDINLL 184
Query: 652 VLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTDHVCSLTPSXF 831
+ K F +PVGYS LG H TLDK + G DH SL P F
Sbjct: 185 AINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKVIEKHFTLDKELPGPDHKASLDPQEF 244
>UniRef50_A2C5V5 Cluster: Sialic acid synthase; n=1; Prochlorococcus
marinus str. MIT 9303|Rep: Sialic acid synthase -
Prochlorococcus marinus (strain MIT 9303)
Length = 335
Score = 123 bits (296), Expect = 6e-27
Identities = 76/245 (31%), Positives = 111/245 (45%), Gaps = 7/245 (2%)
Frame = +1
Query: 118 IIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGKT 297
IIAEAG NH G+ GA +KFQ E + + Y + T
Sbjct: 5 IIAEAGVNHNGEIQNAYRLIDSAKFAGADAIKFQSFSSIELTAENAPKAKYQQMYADRST 64
Query: 298 YGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNL 477
E + LE ++ +++ + Y +++ I F ++A D L+ LKV IK+ SG+ +
Sbjct: 65 QREMLARLELNEMEHQLIADYCEKIEIEFLSTAFGQSQLDLLIKLKVQAIKVASGEITHW 124
Query: 478 LFLKYAASK----KIPLIISTGMVDKTAVKTIYDI-ISSDHK--QFCLLHCISAYPVPFE 636
LK A K + + +STGM + ++ DI I D + +LHC S YP P+
Sbjct: 125 PLLKEMAKKAYENNLDVYLSTGMSEIKEIQDALDIFIKEDISLGKIFILHCTSHYPAPYN 184
Query: 637 DCNLTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTDHVCSL 816
N+ L+ +NTF VGYS G HITLD++MKG DH SL
Sbjct: 185 AVNMKALRTLRNTFQCKVGYSDHTTGILTSVVAVALGAEIIEKHITLDQAMKGPDHKASL 244
Query: 817 TPSXF 831
P F
Sbjct: 245 NPQEF 249
>UniRef50_Q0IDR1 Cluster: N-acetylneuraminic acid condensing enzyme;
n=1; Synechococcus sp. CC9311|Rep: N-acetylneuraminic
acid condensing enzyme - Synechococcus sp. (strain
CC9311)
Length = 347
Score = 121 bits (291), Expect = 3e-26
Identities = 74/244 (30%), Positives = 106/244 (43%), Gaps = 2/244 (0%)
Frame = +1
Query: 91 RIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPY 270
RI +P +I+AE G NH G+ GA VKFQ E + Y
Sbjct: 11 RISSIDPTYIVAEIGVNHNGNISLAHKLIDSAKDAGADAVKFQTYVTDELVIRNTRTAKY 70
Query: 271 DNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIK 450
N+ E S + EL+R+ GI F ++ D VS F+ NLK IK
Sbjct: 71 QKENALFDDQYTMLEKYELSFESFHELYRHCAAAGIDFLSTPFDPVSLRFIANLKPVAIK 130
Query: 451 IGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIIS--SDHKQFCLLHCISAYP 624
SG+ N + L AA ++P+I+STGM + + + D I+ + +L C+S YP
Sbjct: 131 WASGELTNKMLLDQAAKTRLPIILSTGM---SRINDVDDAITWIGRNTPLVVLQCVSNYP 187
Query: 625 VPFEDCNLTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTDH 804
D NL VL +N + PVG+S G H TLD+++ G DH
Sbjct: 188 AAMSDQNLRVLPFLENRYQCPVGFSDHTQGFQCAIAAKGLGMSVLEKHFTLDRNLDGPDH 247
Query: 805 VCSL 816
S+
Sbjct: 248 KASV 251
>UniRef50_Q04TM5 Cluster: N-acetylneuraminic acid (Sialic acid)
synthetase; n=2; Leptospira borgpetersenii serovar
Hardjo-bovis|Rep: N-acetylneuraminic acid (Sialic acid)
synthetase - Leptospira borgpetersenii serovar
Hardjo-bovis (strain JB197)
Length = 282
Score = 120 bits (290), Expect = 3e-26
Identities = 74/246 (30%), Positives = 113/246 (45%)
Frame = +1
Query: 85 DIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLER 264
+I+IGGNNP FIIAEAG NH GD A+ +KFQ E+F +
Sbjct: 9 NIKIGGNNPVFIIAEAGLNHGGDLNLALRMIDEAADAKANAIKFQAYNSEERFGENKEAV 68
Query: 265 PYDNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPF 444
P +GK ++ L +Q+ ILF A+ D+ + + L + V
Sbjct: 69 NLVKPAEFGK-------------KEFLLLKERSQKKNILFFATPFDVPNLNMLKEIGVEI 115
Query: 445 IKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYP 624
+KI S D N+ L+ AA + +I+S G + ++T I F LLHC+S+YP
Sbjct: 116 LKIASCDICNITLLEAAADSGLIVILSRGTASASEIETAVSIFKKKKSPFILLHCVSSYP 175
Query: 625 VPFEDCNLTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTDH 804
+ D NL+ +Q K+ ++ P+GYS G H T+D++++G D
Sbjct: 176 MNEIDANLSAIQTLKSKYEFPIGYSDHSKGIEIPLLAVASGAEIIEKHYTVDRTLQGIDW 235
Query: 805 VCSLTP 822
S P
Sbjct: 236 EISAEP 241
>UniRef50_Q89HL9 Cluster: Blr5971 protein; n=1; Bradyrhizobium
japonicum|Rep: Blr5971 protein - Bradyrhizobium
japonicum
Length = 641
Score = 118 bits (284), Expect = 2e-25
Identities = 73/246 (29%), Positives = 100/246 (40%)
Frame = +1
Query: 94 IGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYD 273
+G PC++IAE G NH GD GA C KFQ L E + L D
Sbjct: 19 LGDGEPCYVIAEVGNNHNGDFDRAIALVDAAVAAGADCAKFQMRKLDEVYRASSLSGK-D 77
Query: 274 NPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKI 453
+ + T + E + Q +++ Y GI + + D S L V K+
Sbjct: 78 DDLAVEYTL-DLLRRFELTTEQQKKIADYCASKGIQYLCTPWDAKSVAVLEGFGVQAYKV 136
Query: 454 GSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVPF 633
S D NL L + LI+STGM +K + + + LLHC S YP
Sbjct: 137 ASADLTNLPLLARLIATGKTLIVSTGMSTTEEIKAAAEFLDERKAGYVLLHCQSTYPAAL 196
Query: 634 EDCNLTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTDHVCS 813
+ +L + + + VGYSG E GT HITLD+ M+G DH S
Sbjct: 197 HNIHLRFMDTLREIHPL-VGYSGHERGTAVSTAAVALGAIVIERHITLDREMEGPDHAAS 255
Query: 814 LTPSXF 831
L P F
Sbjct: 256 LEPEEF 261
>UniRef50_Q8DDZ7 Cluster: Sialic acid synthase; n=5; Bacteria|Rep:
Sialic acid synthase - Vibrio vulnificus
Length = 333
Score = 115 bits (276), Expect = 2e-24
Identities = 89/247 (36%), Positives = 112/247 (45%), Gaps = 8/247 (3%)
Frame = +1
Query: 106 NPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQ--KTCLGEKFTKKYLERPYDNP 279
N FIIAEAG NH GD G VKFQ KT L K E +N
Sbjct: 3 NKTFIIAEAGVNHNGDIRLAKQLIDAAADAGVDAVKFQTWKTELLVTEDAKMAEYQVENT 62
Query: 280 NSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGS 459
+T E LE S + EL Y + GI F ++ + S FL L+ F KIGS
Sbjct: 63 QR-EETQFEMLKRLELSYDDFTELKSYCDDKGITFMSTPDEEQSATFLDGLQAVF-KIGS 120
Query: 460 GDSNNLLFLKYAASKKIPLIISTGM----VDKTAVKTIYDI-ISSDHKQFCLLHCISAYP 624
G+ N FL++ AS P+I+STGM + AV T+ D +S D +LH + YP
Sbjct: 121 GELTNTPFLRHIASFAKPVILSTGMGYLSEVEHAVVTLRDAGLSLD--MITVLHATTDYP 178
Query: 625 VPFEDCNLTVLQDYKNTFD-VPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTD 801
ED NL ++ + F + VGYS LGT H TLDK+M G D
Sbjct: 179 TAPEDVNLLAMKTIEQAFPGIIVGYSDHTLGTEIPVAAVALGAKVIEKHFTLDKTMSGPD 238
Query: 802 HVCSLTP 822
H SL P
Sbjct: 239 HKASLEP 245
>UniRef50_Q893U6 Cluster: N-acetylneuraminate synthase; n=1;
Clostridium tetani|Rep: N-acetylneuraminate synthase -
Clostridium tetani
Length = 351
Score = 115 bits (276), Expect = 2e-24
Identities = 71/253 (28%), Positives = 114/253 (45%), Gaps = 9/253 (3%)
Frame = +1
Query: 91 RIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPY 270
+IG N P +I+AE G NH GD G VKFQ +T K L
Sbjct: 11 KIGENYPAYIVAEIGANHNGDVNLAKRMIEVAAECGVDAVKFQT------YTAKELVSDT 64
Query: 271 DNPNSWG-------KTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVN 429
D +WG +T G+ + ++E+F YA ++G++ ++ + +FL
Sbjct: 65 DRILTWGPCGKQKTETIGKMFDRIALPREAHKEVFEYANKLGLMAFSTPFSIKGVEFLNE 124
Query: 430 LKVPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVD-KTAVKTIYDIISSDHKQFCLLH 606
L+VP K+ + D + L LK K P+++S G A I +I S ++ ++H
Sbjct: 125 LEVPCFKVAASDVDYLDILKEIGKTKKPVMLSLGKCTLGEADLAIETLIESGCEKIVIMH 184
Query: 607 CISAYPVPFEDCNLTVLQDYKNTF-DVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDK 783
C+S YP P + NL V++ K+ + + +G+S +G H TLDK
Sbjct: 185 CVSQYPSPINEMNLKVIEGLKSIYPEFVIGFSDHSMGITADLGAVALGARVIEKHFTLDK 244
Query: 784 SMKGTDHVCSLTP 822
+ G DH S+ P
Sbjct: 245 NTDGPDHWFSMDP 257
>UniRef50_A7GGU3 Cluster: NeuB family protein; n=1; Clostridium
botulinum F str. Langeland|Rep: NeuB family protein -
Clostridium botulinum (strain Langeland / NCTC 10281 /
Type F)
Length = 343
Score = 113 bits (272), Expect = 5e-24
Identities = 78/249 (31%), Positives = 111/249 (44%), Gaps = 2/249 (0%)
Frame = +1
Query: 91 RIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPY 270
++G + FIIAE G NH G+ GA VKFQ + +K Y
Sbjct: 10 KVGEKSSIFIIAEIGVNHNGNIDLAYKLIDLASKAGADAVKFQMF-----YPEKLCSEIY 64
Query: 271 DNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIK 450
K E S ++L Y +G+ F + D S D ++NL IK
Sbjct: 65 R------KDEIEMLKKYVLSFENMKKLRDYTYSLGLEFIVTPFDFKSLDDIINLDCSAIK 118
Query: 451 IGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAV-KTIYDIISSDHKQFCLLHCISAYPV 627
+ SG+ ++ F+K AAS PLIISTG + + V + + I S ++ +LHC+S YP
Sbjct: 119 VASGELTHIPFIKKAASYNKPLIISTGASNLSDVERAVIAIKSVADEKISILHCVSTYPS 178
Query: 628 PFEDCNLTVLQDYKNTF-DVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTDH 804
P E NL L+ + F D +G+S LG HITLDK++KG DH
Sbjct: 179 PDECLNLRALKTLEVAFNDCIIGFSDHSLGYTASNLAVALGASIIEKHITLDKNLKGPDH 238
Query: 805 VCSLTPSXF 831
S + F
Sbjct: 239 KASASQGEF 247
>UniRef50_A4AP54 Cluster: N-acetylneuraminate synthase; n=3;
cellular organisms|Rep: N-acetylneuraminate synthase -
Flavobacteriales bacterium HTCC2170
Length = 351
Score = 113 bits (272), Expect = 5e-24
Identities = 77/259 (29%), Positives = 107/259 (41%), Gaps = 2/259 (0%)
Frame = +1
Query: 61 MVEVKITDDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEK 240
M +KI +D I +PCFIIAEAG NH G G CVKFQ
Sbjct: 1 MKSIKI-EDFLISKESPCFIIAEAGVNHNGKLEMALELVRKAKEIGVDCVKFQTFTAESV 59
Query: 241 FTKKYLERPYD-NPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFD 417
TKK + Y ++ E LE S Y ++ + I F ++ + D
Sbjct: 60 ITKKAPKANYQLEVTDPAESQFEMLKKLELSGDDYIKIIEECNKQNITFLSTPYNEEDAD 119
Query: 418 FLVNLKVPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAV-KTIYDIISSDHKQF 594
FL L V KI SG L FL++ A P+I+S+GM V + + I + + Q
Sbjct: 120 FLNKLGVSAFKIASGQIVELAFLEHVAKFGKPIILSSGMATLAEVYEAVMTIREAGNNQM 179
Query: 595 CLLHCISAYPVPFEDCNLTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHIT 774
+L C + YP ED N+ + N+ D+ GYS H T
Sbjct: 180 AILQCTTNYPSQNEDANIRAMISMGNSLDLIYGYSDHIEENYACFAAVALGAKVIEKHFT 239
Query: 775 LDKSMKGTDHVCSLTPSXF 831
LD+++ G DH SL F
Sbjct: 240 LDRNLPGPDHKASLNVLEF 258
>UniRef50_Q8TJL5 Cluster: N-acetylneuraminic acid phosphate
synthase; n=11; cellular organisms|Rep:
N-acetylneuraminic acid phosphate synthase -
Methanosarcina acetivorans
Length = 286
Score = 113 bits (271), Expect = 7e-24
Identities = 76/244 (31%), Positives = 114/244 (46%), Gaps = 9/244 (3%)
Frame = +1
Query: 118 IIAEAGQNHQGDXXXXXXXXXXXXXX-GASCVKFQKTCLGEKFTKKYLERPYDNP-NSWG 291
+IAE G NH+G+ VKFQK E T + P+ P NS+G
Sbjct: 6 VIAEIGCNHKGEMEIAHEMIKVAAQFCKVDIVKFQKRTPVELLTPEEYNAPHPVPHNSYG 65
Query: 292 KTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSN 471
KTYGEH+ LEF+ Q+++L ++ + G++++ S D+ + +V++ IKI S +
Sbjct: 66 KTYGEHREFLEFNLDQHKQLKKWCDDWGVVYSTSVWDLTAAKEIVSINPELIKIPSACNL 125
Query: 472 NLLFLKYAASKKIPLI-ISTGMV---DKTAVKTIYDIISSDHKQFCLLHCISAYPVPFED 639
L+Y + I +S GM ++ V T ++ K + C S YPVPFED
Sbjct: 126 KFDMLEYLCKEYDGEIHLSFGMTTNEEEEKVVTFFE-DRGRGKDLIIYSCTSGYPVPFED 184
Query: 640 CNLTVLQDYKNTFDVPV---GYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTDHVC 810
L + + F+ V G+SG LG H TLD++ KGTDH
Sbjct: 185 ICLKEILRIRAKFEKRVKGIGFSGHHLGIAADIAALAYGAKYFERHFTLDRTWKGTDHAA 244
Query: 811 SLTP 822
SL P
Sbjct: 245 SLEP 248
>UniRef50_Q9A4G6 Cluster: NeuB protein, putative; n=17;
Bacteria|Rep: NeuB protein, putative - Caulobacter
crescentus (Caulobacter vibrioides)
Length = 356
Score = 111 bits (267), Expect = 2e-23
Identities = 76/253 (30%), Positives = 115/253 (45%), Gaps = 6/253 (2%)
Frame = +1
Query: 91 RIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPY 270
+IG ++ ++I E NH G G +K Q T + T ++RP
Sbjct: 18 KIGADHSPYVICELSGNHNGSLERCLAMVDAAADTGCDAIKIQ-TYTADTITLD-VDRPE 75
Query: 271 DNPNS--W-GKTYGE--HKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLK 435
+ W G+T E ++H F + +F A++ G+ +S D + D L +L
Sbjct: 76 FKIHGGLWDGRTLYELYEEAHTPFE--WHAAIFERARQRGVTIFSSPFDETAVDLLDSLG 133
Query: 436 VPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYD-IISSDHKQFCLLHCI 612
P KI S ++ +L +KYAA+K PLIISTGM + T ++T D +S+ LLHC+
Sbjct: 134 APAFKIASFEAVDLPLIKYAAAKGKPLIISTGMANLTEMQTALDTALSAGAPGVLLLHCV 193
Query: 613 SAYPVPFEDCNLTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMK 792
S+YP F D N+ + D F P+G S GT H TL ++
Sbjct: 194 SSYPATFADANVRTVPDMAARFGCPIGLSDHTPGTAASVAAVSLGACAVEKHFTLARADG 253
Query: 793 GTDHVCSLTPSXF 831
G D SL P+ F
Sbjct: 254 GPDAAFSLEPAEF 266
>UniRef50_A3PE56 Cluster: Sialic acid synthase; n=1; Prochlorococcus
marinus str. MIT 9301|Rep: Sialic acid synthase -
Prochlorococcus marinus (strain MIT 9301)
Length = 341
Score = 110 bits (265), Expect = 4e-23
Identities = 72/246 (29%), Positives = 108/246 (43%), Gaps = 8/246 (3%)
Frame = +1
Query: 118 IIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTK--KYLERPYDNPNSWG 291
+IAEAG NH G GA +KFQ T E L + NS+
Sbjct: 5 VIAEAGVNHNGSLDLALKLVEEAKLSGADSIKFQ-TFKSESLASFSAPLAQYQKKSNSYK 63
Query: 292 KTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSN 471
KS LE +D + +F + E+GI F +S + FL++L + IKI SG+
Sbjct: 64 SQIDMLKS-LELTDKDTKRIFSFCNEIGIEFMSSPFGVDELHFLLDLGMLSIKIPSGEIT 122
Query: 472 NLLFL----KYAASKKIPLIISTGMVDKTAVKTIYDIISSDH--KQFCLLHCISAYPVPF 633
N + K+ + I +++STGM ++ ++ ++ ++HC+S+YP P
Sbjct: 123 NYALISEIGKFISEGNINVLLSTGMSSLGDIEEALSLLRFKETLERITIMHCVSSYPAPN 182
Query: 634 EDCNLTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTDHVCS 813
+D NL VL +N F GYS H+TLDK + G DH S
Sbjct: 183 KDLNLKVLSTLQNCFGCKTGYSDHSENIIAPIISIALGASAIEKHLTLDKDLPGPDHKAS 242
Query: 814 LTPSXF 831
+TP F
Sbjct: 243 ITPKLF 248
>UniRef50_Q4VKA5 Cluster: NeuNAc condensing enzyme; n=54; cellular
organisms|Rep: NeuNAc condensing enzyme - Escherichia
coli
Length = 350
Score = 109 bits (261), Expect = 1e-22
Identities = 78/246 (31%), Positives = 110/246 (44%), Gaps = 10/246 (4%)
Frame = +1
Query: 115 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWG- 291
+I+AE G NH GD G VKFQ T E+ KY + G
Sbjct: 9 YIVAEIGCNHNGDFELAKKMVKEAKSAGVDAVKFQ-TFKAEQLISKYAPKAEYQIKVTGN 67
Query: 292 -KTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDS 468
+T E LE ++ +L YA+E+G+ ++ D S DFL + KI SG+
Sbjct: 68 EETQLEMTRKLELPYDEFIKLEEYAKELGLDVFSTPFDFDSIDFLASRNQKVWKIPSGEL 127
Query: 469 NNLLFLKYAASKKIP---LIISTGM--VDKT--AVKTIYDIISSDHKQFCLLHCISAYPV 627
NL +L+ A I +++STGM VD+ A+K D H+ +LHC + YP
Sbjct: 128 LNLPYLEKIAKLPIEDKKIVLSTGMATVDEINLALKVFIDN-GITHRNITILHCNTEYPT 186
Query: 628 PFEDCNLTVLQDYKNTF-DVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTDH 804
PFED NL + +K F +G+S G H TLDK+ +G DH
Sbjct: 187 PFEDVNLNTISGFKKIFSQYNIGFSDHSPGYFAGIASVPYGITFIEKHFTLDKNFEGPDH 246
Query: 805 VCSLTP 822
S+TP
Sbjct: 247 KASVTP 252
>UniRef50_A3V3D1 Cluster: Polysialic acid capsule biosynthesis
protein SiaC; n=3; Bacteria|Rep: Polysialic acid capsule
biosynthesis protein SiaC - Loktanella vestfoldensis
SKA53
Length = 343
Score = 108 bits (260), Expect = 1e-22
Identities = 69/246 (28%), Positives = 112/246 (45%), Gaps = 1/246 (0%)
Frame = +1
Query: 91 RIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPY 270
+IG +P +IAE G NH GD G VK Q + ++ T++ R
Sbjct: 7 KIGPEHPPLVIAEIGINHGGDLAVAKEMVRLAALSGCEMVKHQTHIIADEMTEE--ARQI 64
Query: 271 DNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIK 450
PN+ + E S + EL RY + +G+++ ++ + DFL +L VP K
Sbjct: 65 FPPNA-DVSIWEVMEACALSLDEEAELKRYTESLGMIWISTPFSRAAADFLQDLDVPAFK 123
Query: 451 IGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVP 630
IGSG+++NL +++ A P+I+STGM +++ I+ + LL C + YP P
Sbjct: 124 IGSGEADNLPLIRHIARMGKPVIMSTGMQSIESIRASVAILDGAGVDYALLECTNLYPSP 183
Query: 631 FEDCNLTVLQDYKNTFD-VPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTDHV 807
E +L + D KN F +G+S +G H T + KG D +
Sbjct: 184 PEIVSLQGVTDLKNAFPRAVIGFSDHSIGPNMALASVALGACILERHYTDSRYRKGPDII 243
Query: 808 CSLTPS 825
S+ P+
Sbjct: 244 NSMDPA 249
>UniRef50_Q2Y4J1 Cluster: NeuB family member; n=5; cellular
organisms|Rep: NeuB family member - uncultured archaeon
Length = 360
Score = 108 bits (260), Expect = 1e-22
Identities = 78/250 (31%), Positives = 114/250 (45%), Gaps = 14/250 (5%)
Frame = +1
Query: 115 FIIAEAGQNH-----QGDXX---XXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPY 270
FI+AEAG N+ +G+ GA +KFQ T E+ KY +
Sbjct: 19 FIVAEAGVNYYDIAKKGNIEPLEAAKLMIEKAADSGADAIKFQ-TYKAERIASKYSPAYW 77
Query: 271 DNPNSWGKT-YGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFI 447
D K+ Y K +F + +Y+EL YA ILF ++ D + DFL L +P
Sbjct: 78 DVTKENTKSQYELFKKFDKFGEDEYKELAGYAANTDILFMSTPFDNEAVDFLDKL-MPVF 136
Query: 448 KIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSD-HKQFCLLHCISAYP 624
KI S D N+ F+ Y A K+ P+ +STG +K + I S+ + + +LHCI YP
Sbjct: 137 KISSSDITNIPFISYVARKRKPIFLSTGASTIEEIKEAVNAIESEGNDKIVILHCILNYP 196
Query: 625 VPFEDCNLTVLQDYKNTF-DVPVGYSGQELGTX---XXXXXXXXXXXXXXXHITLDKSMK 792
+ED NL +++ + F VGYS L H TLDK+++
Sbjct: 197 TKYEDANLGMIKHIQKVFPGYLVGYSDHTLPDSCMLVLTTAVLLGAKVIEKHFTLDKTLQ 256
Query: 793 GTDHVCSLTP 822
G DH S+ P
Sbjct: 257 GNDHYHSMDP 266
>UniRef50_Q89HJ8 Cluster: Blr5992 protein; n=2; Proteobacteria|Rep:
Blr5992 protein - Bradyrhizobium japonicum
Length = 356
Score = 107 bits (258), Expect = 3e-22
Identities = 83/269 (30%), Positives = 107/269 (39%), Gaps = 31/269 (11%)
Frame = +1
Query: 118 IIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQ----KTCLGEKFTKK-YLERPYDNPN 282
IIAEAG NH G GA VKFQ K G K Y +R D
Sbjct: 7 IIAEAGVNHDGSLEKALALVDAAADAGADIVKFQTFNAKALAGGAAKKADYQQRTTDAAE 66
Query: 283 SWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSG 462
S LE + L A E GI F ++ D S FL++LK+P IKIGSG
Sbjct: 67 SQLAML----ERLELPQAAHHTLIERAAERGIEFLSTPFDDASLGFLLSLKLPRIKIGSG 122
Query: 463 DSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDH------------------- 585
D N L AA LI+STGM + ++ +++ +
Sbjct: 123 DLTNAPLLHAAARAGATLILSTGMATLSEIEEALGVLAHGYAQRSDPAGVASFRAAWRDP 182
Query: 586 -------KQFCLLHCISAYPVPFEDCNLTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXX 744
+ LLHC + YP P ED NL + ++ F +PVGYS G
Sbjct: 183 AARATLARHVSLLHCTTEYPCPIEDVNLAAMATMRSAFQLPVGYSDHTDGFEISVAAVAL 242
Query: 745 XXXXXXXHITLDKSMKGTDHVCSLTPSXF 831
H+TLD++ G DH SL P F
Sbjct: 243 GATVIEKHLTLDRNAPGPDHAASLEPGDF 271
>UniRef50_Q12JI6 Cluster: N-acetylneuraminic acid synthase-like
protein; n=1; Shewanella denitrificans OS217|Rep:
N-acetylneuraminic acid synthase-like protein -
Shewanella denitrificans (strain OS217 / ATCC BAA-1090 /
DSM 15013)
Length = 359
Score = 107 bits (258), Expect = 3e-22
Identities = 71/261 (27%), Positives = 110/261 (42%), Gaps = 4/261 (1%)
Frame = +1
Query: 61 MVEVKITDDIR-IGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGE 237
M + IT D R IG +IIAE NH+G G +K Q T
Sbjct: 1 MFKASITIDGRHIGPEYQPYIIAELSGNHKGSLSQALAMIDAAAASGVDAIKIQ-TYTAN 59
Query: 238 KFTKKYLERPYD-NPNSW-GKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVS 411
T ++ + N W G+T + ++ LF +A++ + +S D+ +
Sbjct: 60 TITLQHDGPEFRINGGLWKGRTLFDLYEEAHTPWEWHKSLFEHAKKQNVTLFSSPFDLKA 119
Query: 412 FDFLVNLKVPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISS-DHK 588
+ L + + P KI S + N++ + AA P+++STG+ ++ + +++
Sbjct: 120 IELLESCECPAYKISSFEINDIGLIMAAAKTGKPIVMSTGLATLAEIEEAVEAVANAGGT 179
Query: 589 QFCLLHCISAYPVPFEDCNLTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXH 768
Q LLHCIS YP P EDCNL + D F+ P+G S H
Sbjct: 180 QLALLHCISGYPTPIEDCNLKTVADLCQRFNFPIGLSDHTTDILASVTSVALGASIIEKH 239
Query: 769 ITLDKSMKGTDHVCSLTPSXF 831
TLDK+ G D SL P F
Sbjct: 240 FTLDKTDGGVDAAFSLEPDEF 260
>UniRef50_A4MIF1 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Geobacter bemidjiensis Bem|Rep:
N-acylneuraminate-9-phosphate synthase - Geobacter
bemidjiensis Bem
Length = 338
Score = 107 bits (257), Expect = 3e-22
Identities = 70/240 (29%), Positives = 108/240 (45%), Gaps = 1/240 (0%)
Frame = +1
Query: 109 PCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSW 288
P +IIAE G N G VK Q T E + K +D N+
Sbjct: 10 PIYIIAEIGGNFT-TFEEAKALVDAAASCGVDAVKLQ-TYRAETVSSK--SAIFDMENTG 65
Query: 289 GKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDS 468
+ E E + +R++F Y + G+ + ++ D L L V KIGS D+
Sbjct: 66 IASQFELFQKYEIDEELHRQVFDYIRAKGLDWFSTPSHEADVDLLDRLGVSAYKIGSDDA 125
Query: 469 NNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDII-SSDHKQFCLLHCISAYPVPFEDCN 645
N+ FL+Y A+K P++++TGM V+ D+I + + + LLH +++YP E N
Sbjct: 126 VNIPFLRYVAAKGKPVLLATGMCTMQEVRESVDVILGAGNLELILLHAVTSYPTHPEHVN 185
Query: 646 LTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTDHVCSLTPS 825
L +Q F++PVGYS +GT H T DK+ +G DH+ S P+
Sbjct: 186 LLAMQALAREFNLPVGYSDHTIGTVACLGAAALGAAVLEKHFTTDKNAEGPDHILSADPA 245
>UniRef50_Q1GST3 Cluster: N-acylneuraminate-9-phosphate synthase;
n=2; Alphaproteobacteria|Rep:
N-acylneuraminate-9-phosphate synthase - Sphingopyxis
alaskensis (Sphingomonas alaskensis)
Length = 350
Score = 107 bits (256), Expect = 4e-22
Identities = 74/246 (30%), Positives = 94/246 (38%), Gaps = 9/246 (3%)
Frame = +1
Query: 115 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGK 294
F+IAEAG NH G GA VKFQ E T + Y +
Sbjct: 12 FVIAEAGVNHDGSLDKALRLVDIAVEAGADAVKFQTFRTDEVVTPDAAKAAYQQRQTGAG 71
Query: 295 TYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNN 474
T E LE D + L R+ E GI F ++ + D L+ L + IKI SG+ N
Sbjct: 72 TQYEMIRALELDDAAHERLARHCAERGIEFMSTPFAPWAVDMLLGLGMRRIKIASGEIVN 131
Query: 475 LLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHK---------QFCLLHCISAYPV 627
+ A P+I+STGM + V D I + +LHC S YP
Sbjct: 132 KPLIDKVAGSGRPIILSTGMAEMAEVVRAVDWIRTAQSAAGIAMSPGDLVVLHCTSEYPA 191
Query: 628 PFEDCNLTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTDHV 807
P NL + DVPVGYS LG H T + G DH
Sbjct: 192 PAASVNLRAMDTLAAALDVPVGYSDHSLGIEIAVAAVARGAAVIEKHFTENSRDHGPDHA 251
Query: 808 CSLTPS 825
SL P+
Sbjct: 252 ASLEPA 257
>UniRef50_Q46675 Cluster: NeuB protein; n=8; Bacteria|Rep: NeuB
protein - Escherichia coli
Length = 346
Score = 106 bits (255), Expect = 6e-22
Identities = 76/245 (31%), Positives = 102/245 (41%), Gaps = 9/245 (3%)
Frame = +1
Query: 115 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGK 294
+I+AE G NH G G + VKFQ T +K + + G+
Sbjct: 5 YIVAEIGCNHNGSVDIAREMILKAKEAGVNAVKFQ-TFKADKLISAIAPKAEYQIKNTGE 63
Query: 295 TYG--EHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDS 468
E LE Y L YA + + ++ D S DFL +LK KI SG+
Sbjct: 64 LESQLEMTKKLEMKYDDYLHLMEYAVSLNLDVFSTPFDEDSIDFLASLKQKIWKIPSGEL 123
Query: 469 NNLLFLKYAASKKIP---LIISTGMVDKTAVKTIYDIISSDH---KQFCLLHCISAYPVP 630
NL +L+ A IP +IISTGM +K I ++ +LHC + YP P
Sbjct: 124 LNLPYLEKIAKLPIPDKKIIISTGMATIDEIKQSVSIFINNKVPVGNITILHCNTEYPTP 183
Query: 631 FEDCNLTVLQDYKNTFDV-PVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTDHV 807
FED NL + D K F +G+S G H TLDKSM G DH+
Sbjct: 184 FEDVNLNAINDLKKHFPKNNIGFSDHSSGFYAAIAAVPYGITFIEKHFTLDKSMSGPDHL 243
Query: 808 CSLTP 822
S+ P
Sbjct: 244 ASIEP 248
>UniRef50_UPI0000384B44 Cluster: COG2089: Sialic acid synthase; n=1;
Magnetospirillum magnetotacticum MS-1|Rep: COG2089:
Sialic acid synthase - Magnetospirillum magnetotacticum
MS-1
Length = 346
Score = 103 bits (247), Expect = 6e-21
Identities = 80/243 (32%), Positives = 101/243 (41%), Gaps = 7/243 (2%)
Frame = +1
Query: 115 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGE---KFTKK--YLERPYDNP 279
FIIAEAG NH GD A VKFQ GE +F K YLE +
Sbjct: 14 FIIAEAGVNHDGDIQRAKRLIDVAAEAQADAVKFQTWRPGEITGRFAYKVNYLEATTEQA 73
Query: 280 NSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVN-LKVPFIKIG 456
S Y E L +REL + + GILF ++ S FLV L +P +KIG
Sbjct: 74 ES---RY-ELSCRLALPYPVFRELKSHCEARGILFLSTPDGFDSLAFLVGELDMPIVKIG 129
Query: 457 SGDSNNLLFLKYAASKKIPLIISTGMVDKTAV-KTIYDIISSDHKQFCLLHCISAYPVPF 633
S + + +L+ P I+STG+ V K + + LLHC S YP P
Sbjct: 130 STEVTHPQYLEAIGRTGRPAILSTGLSTLGEVEKAVAALRRGGVGPLALLHCTSEYPAPD 189
Query: 634 EDCNLTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTDHVCS 813
NL + F +PVG S LG H TLD+S+ G DH S
Sbjct: 190 SQMNLRAMTTLGRAFGLPVGLSDHSLGGEAALAAIALGAVIIEKHFTLDRSLPGPDHQAS 249
Query: 814 LTP 822
L P
Sbjct: 250 LDP 252
>UniRef50_Q7MPQ0 Cluster: Sialic acid synthase; n=3;
Proteobacteria|Rep: Sialic acid synthase - Vibrio
vulnificus (strain YJ016)
Length = 357
Score = 103 bits (247), Expect = 6e-21
Identities = 77/264 (29%), Positives = 111/264 (42%), Gaps = 29/264 (10%)
Frame = +1
Query: 118 IIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGK- 294
IIAEAG NH GD GA VKFQ T++ + Y N+ +
Sbjct: 4 IIAEAGVNHNGDEALAFKLVDAAHQAGADIVKFQTFKAKNLVTEQAKQADYQVANTQKQE 63
Query: 295 TYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVN-LKVPFIKIGSGDSN 471
+ S LE S + +L ++ + +GI F ++A D S DFLVN L + +K+ SG+
Sbjct: 64 SQLAMLSRLELSYAAHHQLVKHCESLGIEFLSTAFDSESLDFLVNDLGLTRLKLPSGELT 123
Query: 472 NLLFLKYAASKKIPLIISTGMVDKTAVKTIYDII-----SSDH----------------- 585
N + A LI+STGM ++ +I ++DH
Sbjct: 124 NAPLVLEHARTGCDLIVSTGMATLAEIEMALGVIAFGYTAADHVAPSVLAFQQAYASNEG 183
Query: 586 -----KQFCLLHCISAYPVPFEDCNLTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXX 750
++ +LHC + YP P + NL + FD+P GYS G
Sbjct: 184 QKALKEKVTILHCTTEYPAPMAEINLKAMDTLGKAFDLPAGYSDHSEGITIPIAAVARGA 243
Query: 751 XXXXXHITLDKSMKGTDHVCSLTP 822
H TLDK+M+G DH SL P
Sbjct: 244 VLIEKHFTLDKNMEGPDHKASLEP 267
>UniRef50_A1WSD6 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Verminephrobacter eiseniae EF01-2|Rep:
N-acylneuraminate-9-phosphate synthase -
Verminephrobacter eiseniae (strain EF01-2)
Length = 352
Score = 103 bits (246), Expect = 7e-21
Identities = 65/238 (27%), Positives = 100/238 (42%), Gaps = 3/238 (1%)
Frame = +1
Query: 112 CFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWG 291
C +I E G NH G +K Q+ ++ + Y G
Sbjct: 16 CIVIGEIGVNHNRQQDMLFRLIDEGIAAGLDVIKLQRFKAEQEIAMQAPAADYQKRAGAG 75
Query: 292 KTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVN-LKVPFIKIGSGDS 468
++ + LE D + F Y ++ G+ F +A D S DFL + L +KI S +
Sbjct: 76 ESQLQMARQLELPDAWLTQAFDYCRQRGVGFLCTAFDHGSVDFLADRLGCKTVKIPSPEV 135
Query: 469 NNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDH--KQFCLLHCISAYPVPFEDC 642
+N L++ A + L++STG V D ++++ ++ L+HC+S YP P E
Sbjct: 136 SNKPLLQHMARRFDGLLLSTGASYLGEVANAIDWLAAEAGPRELALMHCLSEYPAPVEQA 195
Query: 643 NLTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTDHVCSL 816
NL + + F VPVGYS G H TLDK++ G DH SL
Sbjct: 196 NLRAMASMRAAFKVPVGYSDHTPGQVAAVVAVGLGAAMIEKHYTLDKNLPGPDHQASL 253
>UniRef50_Q97H26 Cluster: Sialic acid synthase; n=14; cellular
organisms|Rep: Sialic acid synthase - Clostridium
acetobutylicum
Length = 350
Score = 101 bits (243), Expect = 2e-20
Identities = 75/257 (29%), Positives = 116/257 (45%), Gaps = 10/257 (3%)
Frame = +1
Query: 91 RIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFT----KKYL 258
+IG FIIAE NH D GA +K Q T + T +Y
Sbjct: 11 KIGEGQRTFIIAEMSANHNQDFDRAVEIIKAAKRSGADAIKLQ-TYTPDTITFDSDNEYF 69
Query: 259 ERPYDNPNSWGKTYGEHKSHLE-FSDTQYR-ELFRYAQEVGILFTASAMDMVSFDFLVNL 432
+ W T HK + E ++ Q++ +L A+E G++ +S D S DFL +
Sbjct: 70 Q--IKQGTIWDGTT-LHKLYEEAYTPWQWQPKLKEIAEEEGLICFSSPFDNTSVDFLEKM 126
Query: 433 KVPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQ----FCL 600
+VP K+ S + ++ F++Y ASK P+I+STG+ + + IY+ +++ +Q L
Sbjct: 127 EVPAYKVASFELTDIPFIEYIASKGKPVIMSTGIAE---MGEIYEAVAACRRQGNENVIL 183
Query: 601 LHCISAYPVPFEDCNLTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLD 780
L C S+YP P ED NL + + + F+ VG S +G H TL
Sbjct: 184 LKCSSSYPSPLEDINLKTIPNMREAFNCSVGLSDHTMGYSVATAAVALGATVIEKHFTLK 243
Query: 781 KSMKGTDHVCSLTPSXF 831
+S G D S+ P F
Sbjct: 244 RSDGGPDSAFSMEPEEF 260
>UniRef50_Q5QWT8 Cluster: Sialic acid synthase; n=14; Bacteria|Rep:
Sialic acid synthase - Idiomarina loihiensis
Length = 357
Score = 101 bits (241), Expect = 3e-20
Identities = 81/266 (30%), Positives = 113/266 (42%), Gaps = 31/266 (11%)
Frame = +1
Query: 118 IIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGKT 297
IIAEAG NH GD GA VKFQ T+K + Y N G+
Sbjct: 4 IIAEAGVNHNGDAKLARDLVTSAHKAGADIVKFQTFKAKNIVTEKATQANYQKKNL-GRE 62
Query: 298 YGEHK--SHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVN-LKVPFIKIGSGDS 468
+ LE S + EL Y E+GI F ++A D S +FLVN L + +K+ SG+
Sbjct: 63 ESQLAMLQRLELSHELHYELVDYCNELGIEFLSTAFDDESLNFLVNDLGLKRLKLPSGEI 122
Query: 469 NNL-LFLKYAASKKIPLIISTGMVDKTAVKTI-----YDIISSDHKQ------------- 591
N L LK+A + LI+STGM ++++ Y ++ KQ
Sbjct: 123 TNAPLVLKHAQTG-CDLIVSTGMATMAEIESVLGVIAYGYLNPHAKQATRADFETAYASE 181
Query: 592 ---------FCLLHCISAYPVPFEDCNLTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXX 744
+LHC + YP P E+ NL + TF + +GYS G
Sbjct: 182 SGQQILREKVTVLHCTTEYPAPMEEINLNAMNTIGTTFRLQIGYSDHSRGITIPIAAVAK 241
Query: 745 XXXXXXXHITLDKSMKGTDHVCSLTP 822
H TLD++++G DH SL P
Sbjct: 242 GATIIEKHFTLDRNLEGPDHKASLEP 267
>UniRef50_Q93NQ2 Cluster: NnaB; n=7; Bacteria|Rep: NnaB -
Escherichia coli
Length = 346
Score = 101 bits (241), Expect = 3e-20
Identities = 70/245 (28%), Positives = 108/245 (44%), Gaps = 9/245 (3%)
Frame = +1
Query: 115 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGK 294
+I+AE G NH GD G VKFQ T ++ KY + G
Sbjct: 5 YIVAEIGCNHNGDFNLAKKMVEEAKKAGVDAVKFQ-TFKADQLISKYAPKAEYQIKVTGN 63
Query: 295 TYG--EHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDS 468
E LE ++ +L YA+E+G+ ++ D S DFL + KI SG+
Sbjct: 64 QESQLEMTRKLELPYEEFIKLEEYAKELGLDVFSTPFDFESIDFLASRNQKMWKIPSGEL 123
Query: 469 NNLLFLKYAASKKIP---LIISTGMVDKTAVKTIYDIISSDH---KQFCLLHCISAYPVP 630
NL +L+ + I +++STGM +K ++++ + ++ +LHC + YP P
Sbjct: 124 LNLPYLEKISRLPIEGKEIVLSTGMATIEEIKASVNVLTKNGMAPEKITILHCNTEYPTP 183
Query: 631 FEDCNLTVLQDYKNTF-DVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTDHV 807
+ED NL + KN F VG+S G H TL+K+ +G DH
Sbjct: 184 YEDVNLNSIIGLKNEFKGYNVGFSDHSPGYYAAIASVPYGITFIEKHFTLNKNFEGPDHK 243
Query: 808 CSLTP 822
S+TP
Sbjct: 244 ASVTP 248
>UniRef50_Q73P39 Cluster: NeuB family protein; n=1; Treponema
denticola|Rep: NeuB family protein - Treponema denticola
Length = 379
Score = 99.5 bits (237), Expect = 9e-20
Identities = 73/245 (29%), Positives = 105/245 (42%), Gaps = 3/245 (1%)
Frame = +1
Query: 106 NPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNS 285
NP IAE G +H G GA VKFQ E D P
Sbjct: 19 NP-LTIAEIGTSHNGSIQKARNLIDVAAEAGAKAVKFQIVYADEILHPN--TGYVDLPTG 75
Query: 286 WGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGD 465
Y KS LE + Y+EL Y++ +LF+AS S + L LK FIKI S +
Sbjct: 76 KIPLYDRFKS-LELPVSFYKELAEYSRSKKLLFSASPFGFRSAEELAALKPDFIKIASPE 134
Query: 466 SNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQ--FCLLHCISAYPVPFED 639
N + LKY A IP+I+S+G+ ++ + S++K LLHCI++YP P ++
Sbjct: 135 LNYVQLLKYCAGFNIPMILSSGVSILKDIEKAVSFLRSENKDLPLALLHCITSYPAPEKE 194
Query: 640 CNLTVLQDYKNTFDVPVGYSGQELGTXXX-XXXXXXXXXXXXXHITLDKSMKGTDHVCSL 816
N++V+++ F + G S L HI L + +G D +L
Sbjct: 195 YNVSVIKNLSRIFGIACGVSDHSLDPILVPALTLAAGGFIIEKHICLSRKEEGLDDPVAL 254
Query: 817 TPSXF 831
P F
Sbjct: 255 EPDMF 259
>UniRef50_Q0A628 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Alkalilimnicola ehrlichei MLHE-1|Rep:
N-acylneuraminate-9-phosphate synthase - Alkalilimnicola
ehrlichei (strain MLHE-1)
Length = 348
Score = 98.7 bits (235), Expect = 2e-19
Identities = 73/258 (28%), Positives = 108/258 (41%), Gaps = 4/258 (1%)
Frame = +1
Query: 61 MVEVKITDDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEK 240
M E+ I D IG N+P ++IAEAG +H GA +KFQ E
Sbjct: 1 MTELHI-DGRAIGPNHPPYVIAEAGVHHYDSLELARAYVLEARKAGADAIKFQTYTADEL 59
Query: 241 FTKKYLERPYDNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDF 420
T+ Y + + + S T+YR LF YA+E+GI ++ D S D
Sbjct: 60 VTR--WAPLYWTDARFETQHQVFSTKRGLSPTEYRSLFDYARELGITPLSTPFDPASVDL 117
Query: 421 LVNLKVPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCL 600
L L + K+ S D + L+ A K P+++STG V++ +++ S+ L
Sbjct: 118 LDGLGMAAFKVASADITHRPLLQDIAGKGKPVLLSTGAASMAEVRSALEVLESEGVPVAL 177
Query: 601 LHCISAYPVPFEDCNLTVLQDYKNTFDVPV-GYSGQELGTXXXX---XXXXXXXXXXXXH 768
LHC AYP P + NL+ L F V GYS H
Sbjct: 178 LHCSLAYPTPVDQANLSRLGLLAEQFPGRVLGYSDHTPPRDSALPCPASVLLGARVIEKH 237
Query: 769 ITLDKSMKGTDHVCSLTP 822
+L++ + G DH S+ P
Sbjct: 238 FSLNRHLAGDDHYHSVDP 255
>UniRef50_A4B2T9 Cluster: NeuB:Antifreeze-like protein; n=1;
Alteromonas macleodii 'Deep ecotype'|Rep:
NeuB:Antifreeze-like protein - Alteromonas macleodii
'Deep ecotype'
Length = 347
Score = 97.9 bits (233), Expect = 3e-19
Identities = 69/249 (27%), Positives = 105/249 (42%), Gaps = 3/249 (1%)
Frame = +1
Query: 82 DDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLE 261
D I + +IIAE NH GD G S +K Q T + T L+
Sbjct: 4 DQTNINEAHKPYIIAELSANHGGDLSRAKESITKAAEVGVSAIKIQ-TYTPDTMTLDSLQ 62
Query: 262 RPYDNPNS-W-GKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLK 435
+ + W G++ E + + ELF +A+ G+ ++ D + D L +L
Sbjct: 63 DDFIVKDGLWAGRSLYELYTEAYTPYEWHEELFNHAKNCGVTIFSTPFDETAVDLLESLN 122
Query: 436 VPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAV-KTIYDIISSDHKQFCLLHCI 612
P KI S + +L +KY ASK P+++STGM +T + + + + ++ + L HCI
Sbjct: 123 TPAYKIASFEIVDLPLVKYIASKNKPILMSTGMASQTEIEEAVTSVRANGDCELLLFHCI 182
Query: 613 SAYPVPFEDCNLTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMK 792
S+YP ED NL L + F V VG S H LD +
Sbjct: 183 SSYPAVTEDSNLRNLNWLREKFGVEVGLSDHTTNNIAALTAIGMGAVAVEKHFKLDTNDC 242
Query: 793 GTDHVCSLT 819
G D SL+
Sbjct: 243 GPDSSFSLS 251
>UniRef50_Q7NQV6 Cluster: N-acetylneuraminic acid synthase; n=7;
Proteobacteria|Rep: N-acetylneuraminic acid synthase -
Chromobacterium violaceum
Length = 361
Score = 95.9 bits (228), Expect = 1e-18
Identities = 75/267 (28%), Positives = 113/267 (42%), Gaps = 28/267 (10%)
Frame = +1
Query: 106 NPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNS 285
N FIIAEAG NH G GA VKFQ G + + Y +
Sbjct: 2 NHVFIIAEAGVNHNGSLKVALELIDAAKEAGADAVKFQTFKSGAVISMDAPKAEYQKTTT 61
Query: 286 -WGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLV-NLKVPFIKIGS 459
++ + LE S + +L ++ ++ GILF ++ D+ S + LV L VP +K+ S
Sbjct: 62 GTSESQLDMVRKLELSAEDHIQLLQHCEKRGILFLSTPFDVQSAELLVRELGVPQLKVPS 121
Query: 460 GDSNNLLFLKYAASKKIPLIISTGM-------------------VDKTAVKTIY-DIISS 579
G+ N FL A +P+I+STGM + +T +T + + +S
Sbjct: 122 GELTNAPFLLKIAGYGLPVIVSTGMSTLGEAEMALGVLAFGFLGLSETPSETAFRNAFAS 181
Query: 580 D------HKQFCLLHCISAYPVPFEDCNLTVLQDYKNTFDVPVGYSGQELGTXXXXXXXX 741
D ++ +L C + YP PF NL + F +PVG S G
Sbjct: 182 DAGQAVLREKVTILQCTTEYPAPFAQVNLKAMDTLGAAFGLPVGLSDHTPGYAIPIAAVA 241
Query: 742 XXXXXXXXHITLDKSMKGTDHVCSLTP 822
H TLD+++ G DH+ SL P
Sbjct: 242 RGATLIEKHFTLDRNLPGPDHMASLEP 268
>UniRef50_Q30V22 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Desulfovibrio desulfuricans G20|Rep:
N-acylneuraminate-9-phosphate synthase - Desulfovibrio
desulfuricans (strain G20)
Length = 344
Score = 95.9 bits (228), Expect = 1e-18
Identities = 77/249 (30%), Positives = 100/249 (40%), Gaps = 7/249 (2%)
Frame = +1
Query: 94 IGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYD 273
I NP F+IAE G NH+GD GA VK Q G+ + +E P
Sbjct: 5 ISDKNPVFVIAEIGGNHEGDFAYARKLVSLAIESGADAVKLQ-VYAGDALVSR-VESPDR 62
Query: 274 NPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKI 453
N H E S QY L + G+ F ASA D + + V K
Sbjct: 63 N---------RHFKKFELSRGQYEALIDMCRHAGVQFMASAWDRERLGW-IEPHVRIHKA 112
Query: 454 GSGDSNNLLFLKYAASKKIPLIISTGMVD----KTAVKTIYDIISSDHKQ--FCLLHCIS 615
GSGD L+ S PL++STG+ + AV+ I + SS Q LL C S
Sbjct: 113 GSGDLTAYPMLRALVSTGKPLVLSTGLSTMPEVEAAVRYIGSLDSSYITQGKLALLQCSS 172
Query: 616 AYPVPFEDCNLTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKG 795
AYP P D NL V+ + F +PVGYS + H T + K
Sbjct: 173 AYPCPDGDANLNVMHSLRQAFGLPVGYSDHTTDSEAAYAAAVMGAQILELHFTDTREGKS 232
Query: 796 -TDHVCSLT 819
DH+ S+T
Sbjct: 233 FRDHLVSIT 241
>UniRef50_A4U183 Cluster: N-acetylneuraminate synthase; n=1;
Magnetospirillum gryphiswaldense|Rep:
N-acetylneuraminate synthase - Magnetospirillum
gryphiswaldense
Length = 354
Score = 95.9 bits (228), Expect = 1e-18
Identities = 75/260 (28%), Positives = 111/260 (42%), Gaps = 25/260 (9%)
Frame = +1
Query: 118 IIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWG-K 294
IIAEAG NH G GA VKFQ + Y N G +
Sbjct: 5 IIAEAGVNHDGKIDQALRLIDAAAAAGADVVKFQTFKAAALASAVAGRAEYQIRNLGGTE 64
Query: 295 TYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVN-LKVPFIKIGSGDSN 471
+ + LE S+ + L + ++ GI F +S D +S +FL++ L + IK+GSG+
Sbjct: 65 SQLDMLRRLELSEDDHFRLRDHCRQAGIGFLSSPFDRLSLEFLIDRLGLDTIKLGSGELT 124
Query: 472 NLLFLKYAASKKIPLIISTGMVD--KTA--------------VKTIYDIISSDH------ 585
N L A + +I+STGM D +TA T +I ++ H
Sbjct: 125 NGPLLLQAGASGRNIILSTGMADLAETAQAVGVIGCGANGVLAPTESEIQAAAHCPSPDL 184
Query: 586 -KQFCLLHCISAYPVPFEDCNLTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXX 762
++ LLHC + YP P + NL ++ + TF + VG+S G
Sbjct: 185 IRRLTLLHCTTEYPAPMDQVNLRAMETLRQTFGLRVGFSDHTPGITAAVAAAALGASVIE 244
Query: 763 XHITLDKSMKGTDHVCSLTP 822
H+TLD+ + G DH SL P
Sbjct: 245 KHLTLDRGLPGPDHKASLEP 264
>UniRef50_A3Y8V9 Cluster: NeuB family protein; n=1; Marinomonas sp.
MED121|Rep: NeuB family protein - Marinomonas sp. MED121
Length = 347
Score = 95.1 bits (226), Expect = 2e-18
Identities = 66/241 (27%), Positives = 98/241 (40%), Gaps = 5/241 (2%)
Frame = +1
Query: 115 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGK 294
FIIAE NH D G +K Q T + T +
Sbjct: 11 FIIAELSGNHNQDFALAKAMIEAAAKTGVDAIKLQ-TYTADSMTLNVRNEEFMVSAQGSL 69
Query: 295 TYGEHKSHLEF-SDTQY---RELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSG 462
G++ L + T Y + LF YA+ +G++ +S D+ + +FL +L VP KI S
Sbjct: 70 WEGDNLYDLYAKASTPYEWHQPLFDYAKSLGLVAFSSPFDINAVNFLESLDVPIYKIASF 129
Query: 463 DSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIIS-SDHKQFCLLHCISAYPVPFED 639
+ +L ++ A P+I+STGM K+ ++ ++ + LL C S YP ED
Sbjct: 130 ELTDLPLIEAVARTGKPMIMSTGMATKSEIEEAVSLVRLIGDNEITLLKCTSTYPAKIED 189
Query: 640 CNLTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTDHVCSLT 819
NL L D ++F VG S G H LD+S G D S+
Sbjct: 190 SNLITLSDLASSFHCKVGLSDHTQGIAAAVTATALGASVIEKHFVLDRSAGGVDAAFSME 249
Query: 820 P 822
P
Sbjct: 250 P 250
>UniRef50_Q1PVV9 Cluster: Similarity to N-acetyl neuramic acid
synthetase NeuB; n=1; Candidatus Kuenenia
stuttgartiensis|Rep: Similarity to N-acetyl neuramic
acid synthetase NeuB - Candidatus Kuenenia
stuttgartiensis
Length = 277
Score = 94.7 bits (225), Expect = 3e-18
Identities = 65/239 (27%), Positives = 99/239 (41%)
Frame = +1
Query: 103 NNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPN 282
+N ++IAE G NH GD G VKFQ T L EK P ++P
Sbjct: 12 DNKVYVIAEIGLNHGGDMNTAKRLIDSASKTGVDAVKFQ-TYLTEK------RVPKNSP- 63
Query: 283 SWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSG 462
+ E ++EL Y + I F ++ D S DFL ++ K+ S
Sbjct: 64 -----IFDILKKCELPFEVFKELKDYTETYNIEFFSTPFDEESVDFLESVNCALYKVASF 118
Query: 463 DSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVPFEDC 642
D N L A K +I+S GM + + ++ + I+ + + ++HC+SAYP ED
Sbjct: 119 DVVNYKLLSKIADTKKTIIMSVGMANLSEIEGAFKILKNKTDKLAIMHCVSAYPTKEEDA 178
Query: 643 NLTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTDHVCSLT 819
NL+ + K+ FD +G S G H +D+ M D S+T
Sbjct: 179 NLSAIYTLKDKFDCIIGQSDHTAGVTVPLYAIAAGAQIIEKHYKIDEDMNCVDAPVSIT 237
>UniRef50_P39625 Cluster: Spore coat polysaccharide biosynthesis
protein spsE; n=2; Bacillus|Rep: Spore coat
polysaccharide biosynthesis protein spsE - Bacillus
subtilis
Length = 373
Score = 94.3 bits (224), Expect = 3e-18
Identities = 70/248 (28%), Positives = 105/248 (42%), Gaps = 5/248 (2%)
Frame = +1
Query: 94 IGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYD 273
+G + P FIIAEAG NH G GA VKFQ + + Y + P
Sbjct: 11 VGKDAPVFIIAEAGINHDGKLDQAFALIDAAAEAGADAVKFQMF----QADRMYQKDPGL 66
Query: 274 NPNSWGKTYGEHK--SHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFI 447
+ GK +E L Y +E ++F ++ D S D L +
Sbjct: 67 YKTAAGKDVSIFSLVQSMEMPAEWILPLLDYCREKQVIFLSTVCDEGSADLLQSTSPSAF 126
Query: 448 KIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSD-HKQFCLLHCISAYP 624
KI S + N+L LKY A P+I ST + + V + I ++ + Q ++HC++ YP
Sbjct: 127 KIASYEINHLPLLKYVARLNRPMIFSTAGAEISDVHEAWRTIRAEGNNQIAIMHCVAKYP 186
Query: 625 VPFEDCNLTVLQDYKNTF-DVPVGYSG-QELGTXXXXXXXXXXXXXXXXHITLDKSMKGT 798
P E NL+V+ F + +G+S E T H T+DK++ G
Sbjct: 187 APPEYSNLSVIPMLAAAFPEAVIGFSDHSEHPTEAPCAAVRLGAKLIEKHFTIDKNLPGA 246
Query: 799 DHVCSLTP 822
DH +L P
Sbjct: 247 DHSFALNP 254
>UniRef50_A1RHT0 Cluster: N-acylneuraminate-9-phosphate synthase;
n=29; cellular organisms|Rep:
N-acylneuraminate-9-phosphate synthase - Shewanella sp.
(strain W3-18-1)
Length = 349
Score = 93.1 bits (221), Expect = 8e-18
Identities = 68/261 (26%), Positives = 104/261 (39%), Gaps = 5/261 (1%)
Frame = +1
Query: 64 VEVKITDDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKF 243
++V D IG P F+IAE NH GAS +K Q T +
Sbjct: 1 MQVIKVDHCHIGPGQPVFVIAELSGNHGQSLEKAKEMILAAAEAGASAIKLQ-TYTPDTI 59
Query: 244 TKKYLERPY---DNPNSW-GKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVS 411
T + D N W G++ + S ++ LF YA+ +G++ ++ D+ +
Sbjct: 60 TLNVSHGEFFIQDQDNLWKGRSLYDLYSEAMTPWEWHQPLFDYAKSLGLVAFSTPFDLTA 119
Query: 412 FDFLVNLKVPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDH-K 588
++L L VP KI S ++N+ L A P+I+STGM + + ++ +
Sbjct: 120 VEYLEKLNVPCYKIASFENNDHALLAAVAKTGKPVIMSTGMAEIHELAEAVTVLKQHGCR 179
Query: 589 QFCLLHCISAYPVPFEDCNLTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXH 768
LL C S YP D NL+ + FD VG S G H
Sbjct: 180 DLILLKCTSHYPAEPVDANLSTIPHLAQLFDCQVGLSDHTQGIGVSIASVILGGTVIEKH 239
Query: 769 ITLDKSMKGTDHVCSLTPSXF 831
+D++ G D SL P F
Sbjct: 240 FVIDRNEGGVDSEFSLEPREF 260
>UniRef50_A4BEM9 Cluster: Sialic acid synthase; n=1; Reinekea sp.
MED297|Rep: Sialic acid synthase - Reinekea sp. MED297
Length = 354
Score = 92.7 bits (220), Expect = 1e-17
Identities = 77/265 (29%), Positives = 109/265 (41%), Gaps = 24/265 (9%)
Frame = +1
Query: 103 NNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPN 282
N+ F+IAEAG NH GD GA +KFQ T + E +
Sbjct: 3 NDSVFLIAEAGVNHNGDVELAKELIELAAAAGADAIKFQ-TFIPEALVTTTARKAGYQKT 61
Query: 283 SWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSG 462
+ ++ L + EL YA I F ++A + S L L V KI SG
Sbjct: 62 AHEESQLAMLQALALPLPVFDELKAYADSKAIEFMSTAFESESLALLSQLAVRRYKIPSG 121
Query: 463 DSNNLLFLKYAASKKIPLIISTGMVD----KTAVKTIY---------DIISSDHKQFC-- 597
+ NL FL A+ + LI+STGM + A+ +IY IS+ K +
Sbjct: 122 ELTNLPFLIEHAALQQDLILSTGMATLGEIELALASIYWGRVQKDYPPSISALRKAWIER 181
Query: 598 ---------LLHCISAYPVPFEDCNLTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXX 750
LLHC S+YP + N+ + F +PVGYS GT
Sbjct: 182 DPSVALNTTLLHCTSSYPAAPDTVNIRAMTTLAEIFQLPVGYSDHTQGTTASIMAIAKGA 241
Query: 751 XXXXXHITLDKSMKGTDHVCSLTPS 825
H+TLDK++ G DH S++P+
Sbjct: 242 RVIEKHVTLDKTLSGPDHRASMSPA 266
>UniRef50_A4U173 Cluster: NeuB; n=1; Magnetospirillum
gryphiswaldense|Rep: NeuB - Magnetospirillum
gryphiswaldense
Length = 337
Score = 91.9 bits (218), Expect = 2e-17
Identities = 49/171 (28%), Positives = 79/171 (46%), Gaps = 1/171 (0%)
Frame = +1
Query: 322 EFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNLLFLKYAAS 501
E + + EL +E+G+ + ++ + D L K GS D N FL+ A
Sbjct: 77 ELTRDDHVELIDLCRELGVAWMSTPSHVSDLDLLEPFDPIAYKTGSDDLTNTRFLRQIAE 136
Query: 502 KKIPLIISTGMVDKTAVKTIYDIIS-SDHKQFCLLHCISAYPVPFEDCNLTVLQDYKNTF 678
K P+++STGM ++ D+I+ + + + LLHC+ +YP ED NL ++ + F
Sbjct: 137 KGRPMVVSTGMCTLAEIERAVDVITRTGNTELILLHCVVSYPAKAEDANLRAIETLQRAF 196
Query: 679 DVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTDHVCSLTPSXF 831
+PVG S + H TLD ++K DH SL P+ F
Sbjct: 197 GLPVGLSDHTIDEFTSVLATQMGACIIEKHFTLDHALKLPDHQASLDPAAF 247
>UniRef50_Q5R082 Cluster: Sialic acid synthase; n=47; Bacteria|Rep:
Sialic acid synthase - Idiomarina loihiensis
Length = 352
Score = 90.6 bits (215), Expect = 4e-17
Identities = 61/242 (25%), Positives = 97/242 (40%), Gaps = 1/242 (0%)
Frame = +1
Query: 94 IGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYD 273
IG ++ ++AE G NH+G GA +K Q + ++ + +
Sbjct: 18 IGYDHDPVVVAEIGINHEGSLETAYEMVDAAVSAGAEIIKHQTHVVEDEMSA---DAKKV 74
Query: 274 NPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKI 453
P + + E ++ +L Y + G +F ++ + + L + V KI
Sbjct: 75 IPGNADVSIYEIMERCALNEEDETKLKEYVESKGAIFISTPFSRAAAERLERMGVEAYKI 134
Query: 454 GSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVPF 633
GSG+ NN L+ AS K P+I+STGM D ++ DI Q+ LLHC + YP P
Sbjct: 135 GSGECNNYPLLELVASYKKPIILSTGMNDIPSIAKAVDIFRKHGVQYALLHCTNVYPTPD 194
Query: 634 EDCNLTVLQDYKNTF-DVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTDHVC 810
L + ++ F D VG S + H T K G D C
Sbjct: 195 NLIRLGAMNQLQDAFDDAVVGLSDHSIDNLACLGAVAVGASILERHFTDHKQRTGPDINC 254
Query: 811 SL 816
S+
Sbjct: 255 SM 256
>UniRef50_Q04TP3 Cluster: N-acetylneuraminic acid (Sialic acid)
synthetase; n=6; Bacteria|Rep: N-acetylneuraminic acid
(Sialic acid) synthetase - Leptospira borgpetersenii
serovar Hardjo-bovis (strain JB197)
Length = 364
Score = 90.6 bits (215), Expect = 4e-17
Identities = 69/253 (27%), Positives = 115/253 (45%), Gaps = 8/253 (3%)
Frame = +1
Query: 70 VKITDDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQK---TCLGEK 240
+++ + I G +P ++IAE G NH+G GA KFQ L K
Sbjct: 15 IQLGNKIIAGFFDP-YVIAEIGVNHEGSIDIAKRLIDEAKDGGADGAKFQTYKAETLASK 73
Query: 241 FTKKYLERPYDNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDF 420
+ Y +R + S + + ++ S F +Y L ++ Q VGI F ++ D+ + +
Sbjct: 74 NSPSYWDRTQEPTASQFELFKKYDS---FGWKEYEILAKHCQSVGIDFLSTPFDLEAVEH 130
Query: 421 LVNLKVPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVK-TIYDIISSDHKQFC 597
L + ++PFIK+ S D ++ L+ A P+I+STG + + ++ ++ +
Sbjct: 131 LAS-QMPFIKVASADITSVPLLRSVAKYSKPVILSTGSSTIPEIDFAMRELHANGANEII 189
Query: 598 LLHCISAYPVPFEDCNLTVLQDYKNTFDVP-VGYSGQ---ELGTXXXXXXXXXXXXXXXX 765
LLHCI YP E+ NL ++QD + F VGYS +L
Sbjct: 190 LLHCILNYPTKPENANLGMIQDLQRIFPHHWVGYSDHTPPDLEMKSLITATLFGSVVLEK 249
Query: 766 HITLDKSMKGTDH 804
H T DK++ G DH
Sbjct: 250 HFTHDKTLPGNDH 262
>UniRef50_Q11RF6 Cluster: N-acetylneuraminic acid synthetase; n=2;
Flexibacteraceae|Rep: N-acetylneuraminic acid synthetase
- Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB
9469)
Length = 348
Score = 89.0 bits (211), Expect = 1e-16
Identities = 66/247 (26%), Positives = 102/247 (41%), Gaps = 4/247 (1%)
Frame = +1
Query: 94 IGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQK-TCLGEKFTKKYLERPY 270
I N+ F+IAE NH GA +K Q T F E
Sbjct: 9 ISENHKPFVIAEMSGNHNQSLDRALAIVDAAAAAGAHALKLQTYTADTITFNGTSDEFII 68
Query: 271 DNPNSWGKTYGEHKSHLE-FSDTQYRE-LFRYAQEVGILFTASAMDMVSFDFLVNLKVPF 444
+ NS K H+ + + ++ ++ +F A+ G++ +S D + DFL +L VP
Sbjct: 69 KDENSIWKNQNLHQLYQQAYTPWEWHAPIFERAKSHGMIAFSSPFDTTAVDFLESLDVPC 128
Query: 445 IKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDH-KQFCLLHCISAY 621
KI S ++ + + LK A P+I+STG+ ++ ++ + K+ LL C S Y
Sbjct: 129 YKIASFENTDHILLKKVAQTNKPVIMSTGVSTIADIQESVKVLRDNGCKELVLLKCTSTY 188
Query: 622 PVPFEDCNLTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTD 801
P E N+ + FDVPVG S +G H TL ++ G D
Sbjct: 189 PATPESTNIYTIPHMSTLFDVPVGLSDHTMGIGVAIASVALGARIIEKHFTLSRADGGVD 248
Query: 802 HVCSLTP 822
SL P
Sbjct: 249 SSFSLEP 255
>UniRef50_Q18EL3 Cluster: Sialic acid synthase; n=1; Haloquadratum
walsbyi DSM 16790|Rep: Sialic acid synthase -
Haloquadratum walsbyi (strain DSM 16790)
Length = 391
Score = 89.0 bits (211), Expect = 1e-16
Identities = 63/226 (27%), Positives = 97/226 (42%), Gaps = 6/226 (2%)
Frame = +1
Query: 124 AEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGKTYG 303
AE NH G+ GA +K QK + +T++ L Y +P +G TY
Sbjct: 98 AEFTTNHMGNFNVLMRMVEQAVDAGADYIKMQKKDVENFYTEEKLNSNYKSP--YGHTYR 155
Query: 304 EHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNN--- 474
E++ EF T + +++ I + A+ D+ S F++ +P++K+ S +S N
Sbjct: 156 EYRKIFEFDRTDFDRFDEKCEDLDIEWFATPQDIKSLHFVLEYNMPYVKVASTNSRNDEM 215
Query: 475 LLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVPFEDC---N 645
L L+ K L+IS G VK DH L HC+S YPVP E+ N
Sbjct: 216 LTELRDKVPKNTGLVISIGGSTMNEVKDTLSHFP-DHN-IILQHCVSEYPVPPENLGLGN 273
Query: 646 LTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDK 783
+ VL++ + V +GYSG E G H L +
Sbjct: 274 IPVLEEKFGSDRVSIGYSGHETGIGASLAAIDMGAELVERHFCLSR 319
>UniRef50_Q7VHQ5 Cluster: Sialic acid synthase; n=6;
Helicobacter|Rep: Sialic acid synthase - Helicobacter
hepaticus
Length = 349
Score = 87.4 bits (207), Expect = 4e-16
Identities = 68/250 (27%), Positives = 100/250 (40%), Gaps = 12/250 (4%)
Frame = +1
Query: 118 IIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPN---SW 288
IIAE NH GA VK Q +T + L + P+ S
Sbjct: 15 IIAELSANHNQSLEIAKDSIRAIAACGADGVKLQT------YTPECLTLQSNEPHFCISG 68
Query: 289 GKTYGEHKSHLEFSDTQ-----YRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKI 453
G + + + + + Q ++ELF A+E+G+L +S FL +L+ P K+
Sbjct: 69 GTLWDKRNLYELYKEAQTPWEWHKELFSLAKELGLLIFSSPFSPKGVAFLESLQCPIYKV 128
Query: 454 GSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISS-DHKQFCLLHCISAYPVP 630
S + + ++ A K P+IISTG+ +KT +I K LLHCIS YP P
Sbjct: 129 ASFEVMHYELIEAIAKTKKPIIISTGVATHKELKTALEICHKYGCKDITLLHCISEYPAP 188
Query: 631 FEDCNLTVLQDYKNT---FDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTD 801
E NL + T +++ G S LG H LD S+ G D
Sbjct: 189 LESANLLAMPQLAKTYKKYNIKYGLSDHTLGALCPSIATSLGASMIEKHFILDSSLGGVD 248
Query: 802 HVCSLTPSXF 831
S+ F
Sbjct: 249 SAFSMNKDEF 258
>UniRef50_Q726U8 Cluster: NeuB family protein; n=2; Desulfovibrio
vulgaris subsp. vulgaris|Rep: NeuB family protein -
Desulfovibrio vulgaris (strain Hildenborough / ATCC
29579 / NCIMB8303)
Length = 358
Score = 87.0 bits (206), Expect = 5e-16
Identities = 68/241 (28%), Positives = 90/241 (37%), Gaps = 5/241 (2%)
Frame = +1
Query: 118 IIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGKT 297
IIAE G NH GD GA VK Q F L P
Sbjct: 24 IIAEVGLNHGGDADLAWEMIESAWEHGADLVKLQS------FAPGGLLHP-------SLP 70
Query: 298 YGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNL 477
Y + S Q+ LF A+ GI + D + D ++ +K+ S D +N
Sbjct: 71 YAASMEGMMLSLRQHEALFERARRQGIALITTPFDAPTLDLCTRFRIAAVKVASMDLDNT 130
Query: 478 LFLKYAASKKIPLIISTGMVDKTAV-KTIYDIISSDHKQFCLLHCISAYPVPFEDCNLTV 654
L+ A +P+I+S GM D + K + + S LLHCIS YP ED L
Sbjct: 131 AHLRAVARTGLPVILSCGMGDHADIGKALATLRESGATDVTLLHCISDYPARLEDMQLAE 190
Query: 655 LQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSM----KGTDHVCSLTP 822
+ F VPVG S LG H T D ++ DH S+TP
Sbjct: 191 MPRLAARFGVPVGLSDHSLGLEASRMALALGARVIERHFTTDPALMERIPDADHDISITP 250
Query: 823 S 825
+
Sbjct: 251 A 251
>UniRef50_Q2IZW6 Cluster: N-acetylneuraminate synthase; n=1;
Rhodopseudomonas palustris HaA2|Rep: N-acetylneuraminate
synthase - Rhodopseudomonas palustris (strain HaA2)
Length = 332
Score = 83.8 bits (198), Expect = 5e-15
Identities = 67/243 (27%), Positives = 94/243 (38%)
Frame = +1
Query: 103 NNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPN 282
+NP +IIAE G H G GA VKFQ T + E T P
Sbjct: 5 SNP-YIIAEIGSVHDGSFGNACRLLETAAECGADAVKFQ-THIAEAETLPNAPSPSYFSA 62
Query: 283 SWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSG 462
Y + FS Q+R L A+ + F +S + + D L ++ V KI SG
Sbjct: 63 EPRTAYFKRTG---FSPEQWRALAALAKSTKVDFLSSPFSLEAVDLLEDVGVAAYKIPSG 119
Query: 463 DSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVPFEDC 642
+ +N+ L A P+ +S+GM + + + LL C S YP P E
Sbjct: 120 EVSNIPLLSRIAQTGKPVFLSSGMSNWEELDAAVGALRGS--ALTLLQCTSKYPCPPEQV 177
Query: 643 NLTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTDHVCSLTP 822
L + + + +PVGYS LG H T K M G+D S+ P
Sbjct: 178 GLNAMCVMRERYGIPVGYSDHTLGFAAPIAAVALGATVIEKHFTFSKLMYGSDAKNSMEP 237
Query: 823 SXF 831
F
Sbjct: 238 DEF 240
>UniRef50_A0LYV7 Cluster: N-acetylneuraminate synthase; n=1;
Gramella forsetii KT0803|Rep: N-acetylneuraminate
synthase - Gramella forsetii (strain KT0803)
Length = 332
Score = 83.4 bits (197), Expect = 6e-15
Identities = 61/233 (26%), Positives = 91/233 (39%)
Frame = +1
Query: 118 IIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGKT 297
+IAE GQ H+G G VKFQ + E LE + KT
Sbjct: 3 VIAEVGQAHEGSLGMALSYIGALAEAGVDAVKFQ-VHIAEA-ESSILEPFRIKFSEQDKT 60
Query: 298 YGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNL 477
++ +EFS +++ + + ++ + F AS + D L + V KIGSG+ NN
Sbjct: 61 RFDYWKRMEFSTDEWKLIKKTCEDNNVEFLASPFSNAAVDLLEEVGVKRYKIGSGEVNNF 120
Query: 478 LFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVPFEDCNLTVL 657
L L+ A +IIS+GM + + F LL C ++YP + L V+
Sbjct: 121 LLLEKIAKTGKQVIISSGMSSFDELDATVSFLRERKISFSLLQCTTSYPTTPANYGLNVI 180
Query: 658 QDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTDHVCSL 816
Q+ K + V VGYS H + G D SL
Sbjct: 181 QELKQRYKVKVGYSDHSSKIETCIAATAMGAEILEFHAVFSRKSFGPDVSSSL 233
>UniRef50_A6W187 Cluster: N-acylneuraminate-9-phosphate synthase;
n=2; Proteobacteria|Rep: N-acylneuraminate-9-phosphate
synthase - Marinomonas sp. MWYL1
Length = 343
Score = 82.2 bits (194), Expect = 1e-14
Identities = 60/241 (24%), Positives = 93/241 (38%), Gaps = 5/241 (2%)
Frame = +1
Query: 115 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPY---DNPNS 285
FIIAE NH D G +K Q T + T + ++ +
Sbjct: 11 FIIAELSGNHDQDFELAKAMIHAAAEAGVDAIKLQ-TYTPDTMTLDVRHGEFMVSESDSL 69
Query: 286 W-GKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSG 462
W G + ++ LF A+ +G++ +S D+ + FL ++ VP KI S
Sbjct: 70 WRGSNLYDLYKKASTPWEWHKPLFELAESLGLVAFSSPFDLSAVAFLESIDVPLYKIASF 129
Query: 463 DSNNLLFLKYAASKKIPLIISTGMVDKTAV-KTIYDIISSDHKQFCLLHCISAYPVPFED 639
+ ++ ++ A P+I+STGM + + + + I + LL C S YP ED
Sbjct: 130 EMTDIPLIQAVARTGKPIIMSTGMASEEEIAEAVATIRAIGDNPLTLLKCTSTYPSKIED 189
Query: 640 CNLTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTDHVCSLT 819
NL + D PVG S G H LD+S G D S+
Sbjct: 190 SNLVTMADLAAKTGCPVGLSDHTQGLGAAVAATALGATVIEKHFVLDRSAGGVDAEFSME 249
Query: 820 P 822
P
Sbjct: 250 P 250
>UniRef50_Q3B0R9 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Synechococcus sp. CC9902|Rep:
N-acylneuraminate-9-phosphate synthase - Synechococcus
sp. (strain CC9902)
Length = 349
Score = 81.8 bits (193), Expect = 2e-14
Identities = 65/251 (25%), Positives = 100/251 (39%), Gaps = 8/251 (3%)
Frame = +1
Query: 103 NNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQK----TCLGEKFTKKYLERPY 270
+NP + IA+ G NH GA KFQ + + + K+
Sbjct: 7 DNPLYFIADIGANHDSSLKRAKALIKTAAESGADAAKFQNFFAHSIVSDLGFKQLPNSIL 66
Query: 271 DNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIK 450
+ W ++ + S EL Y +E GI + + D+ +FL N V K
Sbjct: 67 SHQAEWTESVFDVYDKASLSLEWTEELHSYCKECGISYMTTPYDISILEFL-NQYVACWK 125
Query: 451 IGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYP-- 624
IGSGD L + + P+ I+TG + T V + + K+ L+ C + Y
Sbjct: 126 IGSGDITWLDLISKVSQLGKPIAIATGASNFTEVCQAVNTVLQHTKKIILMQCNTNYTGC 185
Query: 625 -VPFEDCNLTVLQDYKNTF-DVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGT 798
F+ NL+VL YKN+F + +G S G H T D + KG
Sbjct: 186 LSNFDYLNLSVLTTYKNSFPGITLGISDHTPGHISVLGAITLGAQVIEKHFTDDNNRKGP 245
Query: 799 DHVCSLTPSXF 831
DH S++PS +
Sbjct: 246 DHSFSMSPSAW 256
>UniRef50_Q0P8U0 Cluster: Pse synthetase; n=14; Campylobacter|Rep:
Pse synthetase - Campylobacter jejuni
Length = 343
Score = 81.0 bits (191), Expect = 3e-14
Identities = 67/240 (27%), Positives = 96/240 (40%), Gaps = 6/240 (2%)
Frame = +1
Query: 115 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGK 294
FIIAE NH G GA +K Q T + T L ++ G
Sbjct: 13 FIIAELSANHAGSLEMALKSIKAAKKAGADAIKIQ-TYTPDSLT---LNSDKEDFIIKGG 68
Query: 295 TYGEHKSH--LEFSDTQYR---ELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGS 459
+ + K + E + T Y ++F AQ GIL +S +FL KI S
Sbjct: 69 LWDKRKLYELYESAKTPYEWHSQIFETAQNEGILCFSSPFAKEDVEFLKRFDPIAYKIAS 128
Query: 460 GDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSD-HKQFCLLHCISAYPVPFE 636
++N+ F++ A +K P I+STG+ + + I +I + + L C S YP E
Sbjct: 129 FEANDENFVRLIAKEKKPTIVSTGIATEEELFKICEIFKEEKNPDLVFLKCTSTYPTAIE 188
Query: 637 DCNLTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTDHVCSL 816
D NL + K F+V VG S G H LDKS++ D SL
Sbjct: 189 DMNLKGIVSLKEKFNVEVGLSDHSFGFLAPVMAVALGARVIEKHFMLDKSIESEDSKFSL 248
>UniRef50_Q0YTS4 Cluster: N-acylneuraminate-9-phosphate synthase;
n=5; Bacteria|Rep: N-acylneuraminate-9-phosphate
synthase - Chlorobium ferrooxidans DSM 13031
Length = 354
Score = 80.6 bits (190), Expect = 4e-14
Identities = 60/253 (23%), Positives = 99/253 (39%), Gaps = 7/253 (2%)
Frame = +1
Query: 94 IGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYD 273
+G +P FI+AE NH G GA +K Q T + T + +
Sbjct: 15 LGPGHPAFIVAEMSGNHGGSLEYALEIVHAAKRSGADAIKLQ-TYTADTITLNSDRQDFC 73
Query: 274 NPNSWGKTYGEHKSHLEFSDTQY------RELFRYAQEVGILFTASAMDMVSFDFLVNLK 435
P+ G + +H + + Y +FR A+ + + +S D + + L L
Sbjct: 74 IPS--GTPWADHSTLWSLYNKAYTPWDWHESIFREARSLDLEIFSSPFDESAVELLEQLG 131
Query: 436 VPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVK-TIYDIISSDHKQFCLLHCI 612
KI S + ++ L A P+I+STG+ ++ + + ++ + LL C
Sbjct: 132 ASAYKIASPEITHIPLLDKVARTGKPVILSTGLAALEDIELALATLRAAGSGEIILLKCT 191
Query: 613 SAYPVPFEDCNLTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMK 792
+AYP P E+ NL + D + F V G S G H T+DK+ +
Sbjct: 192 TAYPAPIEEANLRTISDMISRFGVLAGLSDHTTGAISSIVAVSMGASFIEKHFTIDKAKE 251
Query: 793 GTDHVCSLTPSXF 831
D S S F
Sbjct: 252 TVDSFFSADESEF 264
>UniRef50_Q0AN71 Cluster: N-acetylneuraminate synthase; n=1;
Maricaulis maris MCS10|Rep: N-acetylneuraminate synthase
- Maricaulis maris (strain MCS10)
Length = 305
Score = 79.8 bits (188), Expect = 8e-14
Identities = 59/230 (25%), Positives = 92/230 (40%), Gaps = 1/230 (0%)
Frame = +1
Query: 118 IIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGKT 297
+IAE G NH GD GA VKFQ T E ++++ D +
Sbjct: 6 VIAEIGSNHGGDLDQAKRYIEASAKAGADVVKFQ-TLTREGLIARFVKGA-DGTVTENPK 63
Query: 298 YGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNL 477
+ + D + L A + G+ F ++ + + + + +L V KI SGD
Sbjct: 64 FAAF-GNAGLPDDWHAPLMTCAADNGVEFMSTPFSLDAVELMESLGVKRYKIASGDLTFT 122
Query: 478 LFLKYAASKKIPLIISTGMVDKTAVKT-IYDIISSDHKQFCLLHCISAYPVPFEDCNLTV 654
L+ + LI+STG V T + + S LHC ++YP +ED NL+
Sbjct: 123 PLLEALGATGKRLILSTGASYLDEVTTAVTTLTRSGCPHLTALHCAASYPPAWEDLNLSA 182
Query: 655 LQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTDH 804
+ + T +PVG S G H+T D++ G DH
Sbjct: 183 ITTLQKTLGLPVGLSDHSPGAMAPIAAAALGAVVIEKHVTFDRATPGPDH 232
>UniRef50_Q2N2P7 Cluster: NeuB; n=7; Proteobacteria|Rep: NeuB -
Aeromonas hydrophila
Length = 345
Score = 79.4 bits (187), Expect = 1e-13
Identities = 58/194 (29%), Positives = 90/194 (46%), Gaps = 6/194 (3%)
Frame = +1
Query: 94 IGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYD 273
IG ++IAE NH G+ GAS VK Q T + T K +RP
Sbjct: 8 IGPAQAPYVIAELSANHNGNLERALAIMTAAKAAGASAVKLQ-TYRPDTITLKS-DRPEF 65
Query: 274 NPNSWGKTYGEHKSH--LEFSDTQY---RELFRYAQEVGILFTASAMDMVSFDFLVNLKV 438
+ G + H + E++ T + + LF +E+G+ +S D + D L +L
Sbjct: 66 QIH--GGLWDGHSLYDLYEWAHTPWEWHQALFAKGRELGLTVFSSPFDFSAVDLLESLDC 123
Query: 439 PFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDI-ISSDHKQFCLLHCIS 615
P KI S + +L ++YAA PLI+STGM ++ + ++ + Q LLHC+S
Sbjct: 124 PAYKIASFELVDLPLIRYAAQTGKPLIMSTGMANEAEIAAAVEMALKHGSGQLALLHCVS 183
Query: 616 AYPVPFEDCNLTVL 657
YP P + NL +
Sbjct: 184 GYPAPAAEYNLRTI 197
>UniRef50_A2BSE7 Cluster: Sialic acid synthase; n=1; Prochlorococcus
marinus str. AS9601|Rep: Sialic acid synthase -
Prochlorococcus marinus (strain AS9601)
Length = 356
Score = 79.0 bits (186), Expect = 1e-13
Identities = 62/241 (25%), Positives = 101/241 (41%), Gaps = 8/241 (3%)
Frame = +1
Query: 118 IIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQ---KTCLGEKFTKKYLERPYDNPNSW 288
IIAE G NH GD G VKFQ + K +K Y + + S
Sbjct: 23 IIAEIGVNHGGDIDKAIAMIDDVKNNGGDAVKFQTYKANLIARKDSKAYWDTTKEKTMSQ 82
Query: 289 GKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDS 468
+ + ++ +F +++++ Y + +LF ++ D S ++ +N K+ S D
Sbjct: 83 FELFSKYD---KFGLEEFKKIEDYCKRKSVLFMSTPFDSYSANY-INQLSKIHKVASVDI 138
Query: 469 NNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHK-QFCLLHCISAYPVPFEDCN 645
N + + AS +I+STG + +K +I S K LLHC+ YP +D N
Sbjct: 139 TNHILISQLASYGKDIILSTGASNLDEIKAAVSLIESKSKISPALLHCVVNYPTLDKDAN 198
Query: 646 LTVLQDYKNTF-DVPVGYSGQEL---GTXXXXXXXXXXXXXXXXHITLDKSMKGTDHVCS 813
L ++ K +F + +GYS L H T DK ++G DH S
Sbjct: 199 LLRIKKLKESFPENIIGYSDHTLPDKNMIVCTQAYNYGALIIEKHFTYDKKIQGNDHYHS 258
Query: 814 L 816
+
Sbjct: 259 M 259
>UniRef50_Q2BI17 Cluster: N-acetylneuraminate synthase; n=4;
Bacteria|Rep: N-acetylneuraminate synthase -
Neptuniibacter caesariensis
Length = 363
Score = 76.2 bits (179), Expect = 1e-12
Identities = 64/256 (25%), Positives = 96/256 (37%), Gaps = 7/256 (2%)
Frame = +1
Query: 76 ITDDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQK---TCLGEKFT 246
I + I ++P + IA+ NH GD GA KFQ + F
Sbjct: 11 IVNSHSISESDPTYFIADIAANHDGDLEKAKELIWLSAEAGADAAKFQHFKADTIVSDFG 70
Query: 247 KKYLERPYDNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLV 426
K L + ++W K+ E + E EL ++ I F S D D++
Sbjct: 71 FKSLGGQQSHQSTWEKSVYEVYADAEVDLNWTEELVNTCKQAEIDFFTSPYDFDLADYID 130
Query: 427 NLKVPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLH 606
VP KIGSGD L++ A K P ++TG + V + + + L+
Sbjct: 131 QF-VPAHKIGSGDITWHAMLEHIAKKNKPYFLATGASELADVVAAVEACLKINPKLVLMQ 189
Query: 607 CISAYPVPFED---CNLTVLQDYKNTF-DVPVGYSGQELGTXXXXXXXXXXXXXXXXHIT 774
C + Y E+ NL VL+ Y+ F ++ +G S G H T
Sbjct: 190 CNTNYTASLENFAYINLNVLKTYRTLFPELVLGLSDHTPGHSTVLGAVALGARVIEKHFT 249
Query: 775 LDKSMKGTDHVCSLTP 822
D G DH S+ P
Sbjct: 250 DDNQRNGPDHKFSMNP 265
>UniRef50_A7DQU2 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep:
N-acylneuraminate-9-phosphate synthase - Candidatus
Nitrosopumilus maritimus SCM1
Length = 351
Score = 73.3 bits (172), Expect = 7e-12
Identities = 59/243 (24%), Positives = 90/243 (37%), Gaps = 7/243 (2%)
Frame = +1
Query: 115 FIIAEAGQN-----HQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNP 279
F+IAEAG N + D GA VKFQ + Y
Sbjct: 14 FVIAEAGSNWKCGDYSDDLEQAKKLIETAAKAGADAVKFQTYKPETIYVSDAGNSDYLEK 73
Query: 280 NSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGS 459
+ E HL EL +Y E I F ++ + V+ K+ S
Sbjct: 74 YGIKENINEIFEHLSMPYEMIPELKKYCDEKNIQFMSTPFSVQDAKE-VDKFTEIHKVAS 132
Query: 460 GDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSD-HKQFCLLHCISAYPVPFE 636
+ N++ L++ A + P+I+STG + ++I + + L+ C S YP P +
Sbjct: 133 FEINHIRLLEFLAKTQKPIIVSTGASTFKEIDFAINLIRKNGNDNIALMQCTSKYPCPID 192
Query: 637 DCNLTVLQDYKNTFDVPVGYSGQELGTXXX-XXXXXXXXXXXXXHITLDKSMKGTDHVCS 813
NL + + +PVG S L H TLDK++ G DH +
Sbjct: 193 SLNLKTISTMGQKYKIPVGLSDHSLDPIIGPITAISLGAKFIEKHFTLDKNLPGPDHPFA 252
Query: 814 LTP 822
L P
Sbjct: 253 LNP 255
>UniRef50_O83573 Cluster: Spore coat polysaccharide biosynthesis
protein; n=1; Treponema pallidum|Rep: Spore coat
polysaccharide biosynthesis protein - Treponema pallidum
Length = 378
Score = 66.9 bits (156), Expect = 6e-10
Identities = 62/241 (25%), Positives = 93/241 (38%), Gaps = 4/241 (1%)
Frame = +1
Query: 121 IAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGKTY 300
IAE G H G A+ VKFQ E L P+ Y
Sbjct: 18 IAEIGSAHAGSFDRARALIDAAADAAAAAVKFQLIYAHEILHP--LTGAVRLPSGAVSLY 75
Query: 301 GEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNLL 480
+ LE + Y + F +A+ G+L S S + LK F+K+ S + N
Sbjct: 76 -QRFEELEVPLSFYAQCFNHARSRGMLVGISPFGPRSATEALALKPDFLKVASPELNYPT 134
Query: 481 FLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQ---FCLLHCISAYPVPFEDCNLT 651
+ A+ ++PLI+S+G+ ++ KQ LLHCI+AYP P + NL
Sbjct: 135 LISTLAAAELPLILSSGVCLLKEIEGALAQCRQYTKQGSSHALLHCITAYPAPETEYNLA 194
Query: 652 VLQDYKNTFDVPVGYSGQELGTXXX-XXXXXXXXXXXXXHITLDKSMKGTDHVCSLTPSX 828
+L F++ VG S + HI L ++ G D +L P+
Sbjct: 195 LLPALATIFNINVGVSDHSVDPLLVPLLARAHGACIVEKHICLSRTDAGLDDSIALDPAD 254
Query: 829 F 831
F
Sbjct: 255 F 255
>UniRef50_UPI0000E87B4B Cluster: putative N-acetyl neuramic acid
synthetase NeuB; n=1; Methylophilales bacterium
HTCC2181|Rep: putative N-acetyl neuramic acid synthetase
NeuB - Methylophilales bacterium HTCC2181
Length = 615
Score = 64.5 bits (150), Expect = 3e-09
Identities = 60/244 (24%), Positives = 88/244 (36%), Gaps = 1/244 (0%)
Frame = +1
Query: 103 NNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNP- 279
+ P FIIAE G NH GD + +KFQ L + + +
Sbjct: 7 SKPIFIIAEIGINHGGDFSIALELIKAAAQAKVNGIKFQYRNLDNAYADGAKQIGDEMLL 66
Query: 280 NSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGS 459
K Y + L D + E GI F A D+ F ++ F K S
Sbjct: 67 KEITKNYLSPEVILRLVDDAHS----LDIEAGISFFDEA-DIADFGDGIH-HFDFFKSPS 120
Query: 460 GDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVPFED 639
+ NN + P+ +S G + + + ++ D + LHC+S YPV +
Sbjct: 121 VELNNAPLINKMLGFDKPVYVSLGCHHEDQIDDAF--MALDKNNWIALHCVSNYPVSLSN 178
Query: 640 CNLTVLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTDHVCSLT 819
+L L + + P GYS + HIT DK+ G DH S T
Sbjct: 179 AHLGYLSHMREKWQRPYGYSSHDEDWEVCLIAMSMGATVIERHITFDKNADGLDHTTSST 238
Query: 820 PSXF 831
P F
Sbjct: 239 PEEF 242
>UniRef50_Q2BJD7 Cluster: N-acetylneuraminic acid synthetase; n=1;
Neptuniibacter caesariensis|Rep: N-acetylneuraminic acid
synthetase - Neptuniibacter caesariensis
Length = 270
Score = 64.5 bits (150), Expect = 3e-09
Identities = 53/240 (22%), Positives = 93/240 (38%), Gaps = 3/240 (1%)
Frame = +1
Query: 121 IAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGKTY 300
IAE G N GD GA+ KFQ +K +DN G+
Sbjct: 4 IAEIGWNFMGDMKLAEDMIAAAAQSGATTAKFQYWN-----PEKLKAGAWDND---GRRE 55
Query: 301 GEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNLL 480
+K+ L Q +L + + F S + +F+ IKI S + N+
Sbjct: 56 IYNKACLNADKIQ--QLTELCSKHNVKFLLSVFNKEDAEFVSQFSTEAIKIPSHEVANIE 113
Query: 481 FLKYAASKKIPLIISTGMVDKTAVKTIYDIISS---DHKQFCLLHCISAYPVPFEDCNLT 651
++YA S + +S G + +K + +++ S + + +HC+S+YP P E NL
Sbjct: 114 LIRYALSTYKRVFLSLGACTEEELKDVSELVGSIRSNGEDVVAMHCVSSYPCPVEKVNLP 173
Query: 652 VLQDYKNTFDVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKGTDHVCSLTPSXF 831
+ + + F+ +G S H T++ + G D+ ++ P F
Sbjct: 174 RMAELQKLFNGELGLSDHSQSVNVPAYAVAMGATVIEKHFTVNHDLPGRDNKFAVLPEGF 233
>UniRef50_A0LAB4 Cluster: N-acetylneuraminic acid synthase,
N-terminal domain; n=2; Proteobacteria|Rep:
N-acetylneuraminic acid synthase, N-terminal domain -
Magnetococcus sp. (strain MC-1)
Length = 500
Score = 63.7 bits (148), Expect = 5e-09
Identities = 59/242 (24%), Positives = 92/242 (38%), Gaps = 7/242 (2%)
Frame = +1
Query: 115 FIIAEAGQN----HQG-DXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNP 279
+IIAEAG N H D GA VKFQ + + + Y
Sbjct: 161 YIIAEAGSNWRMGHPARDLAMGKALIDAAVVSGADAVKFQTYRPEKVYVANAGQSNYLAE 220
Query: 280 NSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGS 459
+ + + + L + +L Y ++ GI F ++ + F ++ VP KI S
Sbjct: 221 SGIKQDIRDIFADLAMPYSMIEDLAGYCKKAGIQFLSTGFSVEDFQ-AIDPWVPLHKIAS 279
Query: 460 GDSNNLLFLKYAASKKIPLIISTGMVDKTAVK-TIYDIISSDHKQFCLLHCISAYPVPFE 636
+ ++L L AA+ PL++STG + + S + CLL C + YP P
Sbjct: 280 YEISHLRLLDLAANSGKPLLLSTGASRAEDIAWAVERYHSQGGRDLCLLQCTAKYPAPLA 339
Query: 637 DCNLTVLQDYKNTFDVPVGYSGQELGTXXX-XXXXXXXXXXXXXHITLDKSMKGTDHVCS 813
N VL + + V VG S H TL ++ G DH +
Sbjct: 340 TVNSAVLPWLQRRYGVSVGLSDHSRDPITAPVAAVAQGARCIEKHYTLHNALPGPDHSFA 399
Query: 814 LT 819
+T
Sbjct: 400 IT 401
>UniRef50_Q8EC83 Cluster: Polysaccharide biosynthesis
related-protein; n=6; Proteobacteria|Rep: Polysaccharide
biosynthesis related-protein - Shewanella oneidensis
Length = 290
Score = 63.3 bits (147), Expect = 7e-09
Identities = 59/206 (28%), Positives = 87/206 (42%), Gaps = 7/206 (3%)
Frame = +1
Query: 103 NNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPN 282
++P FI AE NH D G VKFQ + E F + L +
Sbjct: 4 HSPLFI-AEVSSNHHRDLQRCIEFIKTAAEIGCDAVKFQLFKIEELFAPEILSK------ 56
Query: 283 SWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSG 462
+ E + +L + E GI F+ + + D + L+ PF+
Sbjct: 57 ---SEMHRKRKEWELPVSFLPQLKQSCDEYGIQFSCTPFYL---DAVAELE-PFVDFYKI 109
Query: 463 DSNNLLF---LKYAASKKIPLIISTGMVD----KTAVKTIYDIISSDHKQFCLLHCISAY 621
S LL+ L P++IS GM A+KT+ + +SD LLHC+SAY
Sbjct: 110 ASYELLWDDLLAACVKTGKPVVISAGMATIEEIDHALKTLKENGASD---ITLLHCVSAY 166
Query: 622 PVPFEDCNLTVLQDYKNTFDVPVGYS 699
P P +CNL VL ++N + V VG+S
Sbjct: 167 PTPEHECNLAVLGSFRNRYQVKVGWS 192
>UniRef50_Q319P5 Cluster: Putative spore coat polysaccharide
biosynthesis protein E; n=1; Prochlorococcus marinus
str. MIT 9312|Rep: Putative spore coat polysaccharide
biosynthesis protein E - Prochlorococcus marinus (strain
MIT 9312)
Length = 521
Score = 55.2 bits (127), Expect = 2e-06
Identities = 33/128 (25%), Positives = 56/128 (43%), Gaps = 2/128 (1%)
Frame = +1
Query: 331 DTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNLLFLKYAASKKI 510
D Q+ ++ ++ G + D S + + KI S L+ A++
Sbjct: 88 DEQWLQILNMVRDKGFKTIVTPFDEASVNKAERFGIEEYKIASCSCTEWSLLREVANQNK 147
Query: 511 PLIISTGMVDKTAVKTIYDIISSDHK-QFCLLHCISAYPVPFEDCNLTVLQDYKNTFDV- 684
P+ ISTG + V IY + +F ++HC YP P +D NL + +K + +
Sbjct: 148 PVTISTGGRNLKEVDDIYSYFAHRIPYKFTIMHCCGIYPAPIKDLNLNTINIFKERYPLA 207
Query: 685 PVGYSGQE 708
+GYSG E
Sbjct: 208 KIGYSGHE 215
>UniRef50_Q2AHF7 Cluster: Antifreeze-like; n=1; Halothermothrix
orenii H 168|Rep: Antifreeze-like - Halothermothrix
orenii H 168
Length = 350
Score = 51.6 bits (118), Expect = 2e-05
Identities = 47/198 (23%), Positives = 82/198 (41%), Gaps = 3/198 (1%)
Frame = +1
Query: 115 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGK 294
+II E NHQGD G VKF E YL+ N + K
Sbjct: 4 YIIGETAYNHQGDIHYLKRMIDDIAEIGLQAVKFHLLLNPES----YLQ----NKHPLIK 55
Query: 295 TYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFL--VNLKVPFIKIGSGDS 468
E F++ ++ E+ Y+++ G+ A D+ S F+ + + I+I +
Sbjct: 56 KIKEWI----FTEKEWDEIINYSKQKGLDMIALCDDLDSLKFIKKYHRDLKGIEIHASSL 111
Query: 469 NNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQ-FCLLHCISAYPVPFEDCN 645
N+ L+ A +I+ G ++ + + K+ L++ +YP + N
Sbjct: 112 NDYFLLEEARDFPNSVILGIGGSTLDEIEYAVNFLKQRGKEDIILMYGFQSYPTDYTQIN 171
Query: 646 LTVLQDYKNTFDVPVGYS 699
L +Q KN F++PVGY+
Sbjct: 172 LAKMQKLKNLFNLPVGYA 189
>UniRef50_A5W0I0 Cluster: N-acetylneuraminic acid synthase,
N-terminal domain; n=1; Pseudomonas putida F1|Rep:
N-acetylneuraminic acid synthase, N-terminal domain -
Pseudomonas putida F1
Length = 369
Score = 51.2 bits (117), Expect = 3e-05
Identities = 29/127 (22%), Positives = 52/127 (40%)
Frame = +1
Query: 298 YGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNL 477
Y + + ++ + + + + A+ D S D V +P IKI S D N+
Sbjct: 74 YVKKTEDTRLTKAEFARMVEEVRNLSCIPMATPFDEASVDLCVEFDMPIIKIASSDMNDW 133
Query: 478 LFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVPFEDCNLTVL 657
++ AS + P IISTG + + I + HC+S YP ++ L +
Sbjct: 134 PLIEKIASTRRPTIISTGGASEKDLDDIVRYFEKRDIPLAINHCVSLYPSEDDELQLDQI 193
Query: 658 QDYKNTF 678
+N +
Sbjct: 194 DYLRNRY 200
>UniRef50_Q9P0B2 Cluster: HSPC269; n=2; Homo sapiens|Rep: HSPC269 -
Homo sapiens (Human)
Length = 120
Score = 49.6 bits (113), Expect = 1e-04
Identities = 23/55 (41%), Positives = 29/55 (52%), Gaps = 1/55 (1%)
Frame = +1
Query: 634 EDCNLTVLQDYKNTF-DVPVGYSGQELGTXXXXXXXXXXXXXXXXHITLDKSMKG 795
ED NL V+ +Y+ F D+P+GYSG E G HITLDK+ KG
Sbjct: 3 EDVNLRVISEYQKLFPDIPIGYSGHETGIAISVAAVALGAKVLERHITLDKTWKG 57
>UniRef50_Q0IDQ4 Cluster: NeuB family protein; n=1; Synechococcus
sp. CC9311|Rep: NeuB family protein - Synechococcus sp.
(strain CC9311)
Length = 353
Score = 46.8 bits (106), Expect = 7e-04
Identities = 35/123 (28%), Positives = 54/123 (43%), Gaps = 2/123 (1%)
Frame = +1
Query: 337 QYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNLLFLKYAASKKIPL 516
Q+RELF + G+ F S + S DF V+ IKI S + N L ++ +A +PL
Sbjct: 96 QHRELFNLIKSYGLNFIVSVYTLESVDFAVSEGAIAIKIASSNINFLPLIEKSARTGLPL 155
Query: 517 IISTGMVDKTAVKTIYDIISSDHKQFCLL--HCISAYPVPFEDCNLTVLQDYKNTFDVPV 690
+I TG + S ++ L+ H +A P P E +L+ + N
Sbjct: 156 LIDTGKSTLCEIFEARHAAYSANQDVKLIFEHSPAAPPAPIERQDLSFMNYLSNLLGEHA 215
Query: 691 GYS 699
G S
Sbjct: 216 GLS 218
>UniRef50_A5IGD9 Cluster: Spore coat polysaccharide biosynthesis
protein E; n=5; Legionella pneumophila|Rep: Spore coat
polysaccharide biosynthesis protein E - Legionella
pneumophila (strain Corby)
Length = 368
Score = 46.8 bits (106), Expect = 7e-04
Identities = 30/121 (24%), Positives = 54/121 (44%), Gaps = 1/121 (0%)
Frame = +1
Query: 340 YRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNLLFLKYAASKKIPLI 519
Y LF + + F S ++ + DF + +K S + ++ +++ A +PLI
Sbjct: 107 YSMLFSLLKNANLPFIVSIYELDTIDFAIKQGACALKTSSSNIVHIPLIRHLAKTGLPLI 166
Query: 520 ISTGMVDKTAV-KTIYDIISSDHKQFCLLHCISAYPVPFEDCNLTVLQDYKNTFDVPVGY 696
I TG T + K + S+ ++ + H +P E NL +L+ F +PVG
Sbjct: 167 IDTGRSSLTDICKAVETAKSAGCEKIIIEHSPDGHPALPEAHNLRMLRTLNQCFSLPVGL 226
Query: 697 S 699
S
Sbjct: 227 S 227
>UniRef50_Q7NR94 Cluster: Probable spore coat polysaccharide
biosynthesis protein E; n=1; Chromobacterium
violaceum|Rep: Probable spore coat polysaccharide
biosynthesis protein E - Chromobacterium violaceum
Length = 495
Score = 41.9 bits (94), Expect = 0.019
Identities = 27/125 (21%), Positives = 52/125 (41%), Gaps = 1/125 (0%)
Frame = +1
Query: 337 QYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNLLFLKYAASKKIPL 516
Q ++L + G + D S D + + IKI S + L+ A P+
Sbjct: 77 QMQKLVAEMKANGFKAICTPFDEESVDLIEAHGIEIIKIASCSFTDWPLLERIARSDKPV 136
Query: 517 IISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVPFEDCNLTVLQDYKNTF-DVPVG 693
+ ST + + + + K ++HC++ YP P + +L ++ + + V +G
Sbjct: 137 VASTAGARREDIDKVVSFMLHRGKDLTIMHCVAEYPTPDDHLHLARIKTLRQQYAGVRIG 196
Query: 694 YSGQE 708
YS E
Sbjct: 197 YSTHE 201
>UniRef50_UPI0000F219ED Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 100
Score = 37.5 bits (83), Expect = 0.41
Identities = 15/36 (41%), Positives = 24/36 (66%)
Frame = +1
Query: 397 MDMVSFDFLVNLKVPFIKIGSGDSNNLLFLKYAASK 504
MD ++ +FL + VPF K+ S D+NN+ +L+ A K
Sbjct: 1 MDEMAVEFLHEINVPFFKVASADTNNIPYLEKTAKK 36
>UniRef50_Q8RI47 Cluster: Tetratricopeptide repeat family protein;
n=1; Fusobacterium nucleatum subsp. nucleatum|Rep:
Tetratricopeptide repeat family protein - Fusobacterium
nucleatum subsp. nucleatum
Length = 628
Score = 34.3 bits (75), Expect = 3.8
Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Frame = +1
Query: 364 QEVGILFTASA-MDMVSFDFLVNLKVPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVD 540
+E+GI +T S D+++ + NL FIK+ SG+ Y K M+D
Sbjct: 548 EEIGIFYTPSGKQDIINNKY--NLPEDFIKLKSGEIKTFFIDWYNNKTKEKFYELFNMID 605
Query: 541 KTAVKTIYDIISSDHK 588
KT++K ++++ K
Sbjct: 606 KTSIKVYLKYLNTEKK 621
>UniRef50_Q5A950 Cluster: Sterol 3-beta-glucosyltransferase; n=2;
Candida albicans|Rep: Sterol 3-beta-glucosyltransferase -
Candida albicans (Yeast)
Length = 1513
Score = 33.9 bits (74), Expect = 5.1
Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 4/68 (5%)
Frame = +1
Query: 214 FQKTCLG--EKFTKKYLERPYDNPNSWGKTYGE--HKSHLEFSDTQYRELFRYAQEVGIL 381
FQK L E+ K RP P WG + +K+ +E+SD++ RE+ +Y + I
Sbjct: 912 FQKVVLSVLERLHSKEGFRP--EPYQWGSNFEVELYKTRMEYSDSENREIQQYDNSIDIK 969
Query: 382 FTASAMDM 405
F ++M
Sbjct: 970 FAEKKIEM 977
>UniRef50_Q7VQK1 Cluster: Survival protein SurA; n=1; Candidatus
Blochmannia floridanus|Rep: Survival protein SurA -
Blochmannia floridanus
Length = 426
Score = 33.5 bits (73), Expect = 6.7
Identities = 21/68 (30%), Positives = 35/68 (51%)
Frame = +1
Query: 463 DSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVPFEDC 642
D N L + S++I IST +++TA K + + HKQF +H I P+P E
Sbjct: 136 DILNKLICNHIISQRIK--ISTHEINQTAQKLSF---INFHKQFKFIHTIIELPIPAETT 190
Query: 643 NLTVLQDY 666
+ +L ++
Sbjct: 191 QINILNNF 198
>UniRef50_Q54FM7 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 888
Score = 33.1 bits (72), Expect = 8.8
Identities = 35/154 (22%), Positives = 66/154 (42%), Gaps = 6/154 (3%)
Frame = +1
Query: 205 CVKFQKTCLGEKFTKKYLERPYDNPNSWGKTY-GEHKSHLEFSDTQYRELFRYAQEVG-- 375
C +F K E F K + Y N NS KT H ++ E ++ ++ ++
Sbjct: 379 CYRFNKDRCLESFLIKQFRKTYSNSNSNSKTVLFSHCNNKEKQIEFINQVIKFKNDLPNP 438
Query: 376 ILFTASAMDMVSFDFLVNLKVPFI---KIGSGDSNNLLFLKYAASKKIPLIISTGMVDKT 546
+LF + S + + ++ F + ++NNLL K + KIP II+ +
Sbjct: 439 LLFFYLVISFDSLELIKMVEKGFTDNNNNNNNNNNNLLEYKETYNNKIPFIITRYIRSIQ 498
Query: 547 AVKTIYDIISSDHKQFCLLHCISAYPVPFEDCNL 648
++ +++ +HK + S+Y F + NL
Sbjct: 499 VMEYLFE----NHKNHFIQTSSSSYISFFINLNL 528
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 808,458,612
Number of Sequences: 1657284
Number of extensions: 15868755
Number of successful extensions: 37526
Number of sequences better than 10.0: 92
Number of HSP's better than 10.0 without gapping: 36135
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 37358
length of database: 575,637,011
effective HSP length: 100
effective length of database: 409,908,611
effective search space used: 72553824147
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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