Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P05_F_K01
(840 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P48735 Cluster: Isocitrate dehydrogenase [NADP], mitoch... 361 2e-98
UniRef50_Q8LPJ5 Cluster: Isocitrate dehydrogenase-like protein; ... 341 1e-92
UniRef50_Q9SRZ6 Cluster: F12P19.10 protein; n=26; cellular organ... 337 2e-91
UniRef50_Q0CXI1 Cluster: Isocitrate dehydrogenase, mitochondrial... 291 2e-77
UniRef50_A2WMU2 Cluster: Putative uncharacterized protein; n=5; ... 289 8e-77
UniRef50_A5ZVX5 Cluster: Putative uncharacterized protein; n=1; ... 267 3e-70
UniRef50_A5N5L9 Cluster: Idh; n=2; Bacteria|Rep: Idh - Clostridi... 260 4e-68
UniRef50_UPI0000F1EC8D Cluster: PREDICTED: similar to Isocitrate... 220 3e-56
UniRef50_A2XVE4 Cluster: Putative uncharacterized protein; n=2; ... 105 4e-34
UniRef50_Q2K7T8 Cluster: NADP-dependent isocitrate dehydrogenase... 114 2e-24
UniRef50_A3K670 Cluster: NADP-dependent isocitrate dehydrogenase... 114 2e-24
UniRef50_Q5DBI8 Cluster: SJCHGC09598 protein; n=1; Schistosoma j... 113 7e-24
UniRef50_A4VDP7 Cluster: Putative uncharacterized protein; n=1; ... 95 3e-18
UniRef50_A3JDN6 Cluster: Isocitrate dehydrogenase; n=5; Gammapro... 92 1e-17
UniRef50_Q00WM7 Cluster: COG0538: Isocitrate dehydrogenases; n=3... 90 6e-17
UniRef50_Q4VCC2 Cluster: Isocitrate dehydrogenase; n=4; Eukaryot... 79 1e-13
UniRef50_Q67N12 Cluster: 3-isopropylmalate dehydrogenase; n=5; B... 51 3e-05
UniRef50_Q40658 Cluster: Isocitrate dehydrogenase; n=1; Oryza sa... 43 0.011
UniRef50_A0KSD7 Cluster: Putative uncharacterized protein; n=2; ... 34 5.1
UniRef50_O17998 Cluster: Putative uncharacterized protein; n=2; ... 33 6.8
UniRef50_Q09277 Cluster: Putative uncharacterized protein F40H6.... 33 6.8
UniRef50_Q0HEG1 Cluster: Conserved hypothetical biogenesis prote... 33 8.9
>UniRef50_P48735 Cluster: Isocitrate dehydrogenase [NADP],
mitochondrial precursor (EC 1.1.1.42) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH); n=493;
cellular organisms|Rep: Isocitrate dehydrogenase [NADP],
mitochondrial precursor (EC 1.1.1.42) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) - Homo
sapiens (Human)
Length = 452
Score = 361 bits (887), Expect = 2e-98
Identities = 165/235 (70%), Positives = 192/235 (81%), Gaps = 1/235 (0%)
Frame = +2
Query: 137 RNYGTAKRVVAAKPVVEMDGDEMTRIMWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQ 316
R + KR+ AKPVVEMDGDEMTRI+W IKE+LI P+V + YFDLGLP+RD TDDQ
Sbjct: 36 RRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQ 95
Query: 317 VTIDSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQ 496
VTIDSA A K++V +KCATITPDE RVEEFKLKKMW SPNGTIRNILGGTVFREPI+C+
Sbjct: 96 VTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICK 155
Query: 497 SIPRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTRDGT-TERRVLYDFKTP 673
+IPR+VPGWTKPI IGRHAHGDQYKA DFV + G ++V+T +DG+ + +Y+F
Sbjct: 156 NIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAG 215
Query: 674 GVAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEXVF 838
GV MGMYNTDESI FAHS FQ A+QKKWPLY+STKNTILK YDGRFKDIF+ +F
Sbjct: 216 GVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIF 270
>UniRef50_Q8LPJ5 Cluster: Isocitrate dehydrogenase-like protein;
n=6; core eudicotyledons|Rep: Isocitrate
dehydrogenase-like protein - Arabidopsis thaliana
(Mouse-ear cress)
Length = 485
Score = 341 bits (838), Expect = 1e-92
Identities = 154/232 (66%), Positives = 187/232 (80%), Gaps = 1/232 (0%)
Frame = +2
Query: 146 GTAKRVVAAKPVVEMDGDEMTRIMWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTI 325
G + R+ P+VEMDGDEMTR++W+ IKE+LI PY+ +D YFDLG+ +RDATDD+VT+
Sbjct: 71 GGSDRIQVQNPIVEMDGDEMTRVIWSMIKEKLILPYLDLDIKYFDLGILNRDATDDKVTV 130
Query: 326 DSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIP 505
+SA A LK+NV IKCATITPDE RV+EF LK MW SPNGTIRNIL GTVFREPI+C +IP
Sbjct: 131 ESAEAALKYNVAIKCATITPDEGRVKEFGLKSMWRSPNGTIRNILDGTVFREPIMCSNIP 190
Query: 506 RVVPGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTRDGTTERRV-LYDFKTPGVA 682
R+VPGW KPI IGRHA GDQY+A D V+ PGK+++V+ DG + +YDFK PGVA
Sbjct: 191 RLVPGWEKPICIGRHAFGDQYRATDTVIKGPGKLKMVFVPEDGNAPVELDVYDFKGPGVA 250
Query: 683 MGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEXVF 838
+ MYN DESIR+FA SS +AL KKWPLYLSTKNTILK+YDGRFKDIF+ V+
Sbjct: 251 LAMYNVDESIRAFAESSMAMALTKKWPLYLSTKNTILKKYDGRFKDIFQEVY 302
>UniRef50_Q9SRZ6 Cluster: F12P19.10 protein; n=26; cellular
organisms|Rep: F12P19.10 protein - Arabidopsis thaliana
(Mouse-ear cress)
Length = 410
Score = 337 bits (829), Expect = 2e-91
Identities = 151/228 (66%), Positives = 184/228 (80%)
Frame = +2
Query: 155 KRVVAAKPVVEMDGDEMTRIMWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSA 334
+++ A P+VEMDGDEMTR++W IK++LI P+V++D YFDLGLPHRDATDD+VTI+SA
Sbjct: 4 EKIKVANPIVEMDGDEMTRVIWKSIKDKLITPFVELDIKYFDLGLPHRDATDDKVTIESA 63
Query: 335 HAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVV 514
A K+NV IKCATITPDE RV EF LK+MW SPNGTIRNIL GTVFREPI+C+++P++V
Sbjct: 64 EATKKYNVAIKCATITPDEGRVTEFGLKQMWRSPNGTIRNILNGTVFREPIICKNVPKLV 123
Query: 515 PGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTRDGTTERRVLYDFKTPGVAMGMY 694
PGWTKPI IGRHA GDQY+A D V+ PGK+ + + +DG TE V GVAM MY
Sbjct: 124 PGWTKPICIGRHAFGDQYRATDAVIKGPGKLTMTFEGKDGKTETEVFTFTGEGGVAMAMY 183
Query: 695 NTDESIRSFAHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEXVF 838
NTDESIR+FA +S A +KKWPLYLSTKNTILK+YDGRFKDIF+ V+
Sbjct: 184 NTDESIRAFADASMNTAYEKKWPLYLSTKNTILKKYDGRFKDIFQEVY 231
>UniRef50_Q0CXI1 Cluster: Isocitrate dehydrogenase, mitochondrial;
n=2; Eurotiomycetidae|Rep: Isocitrate dehydrogenase,
mitochondrial - Aspergillus terreus (strain NIH 2624)
Length = 466
Score = 291 bits (713), Expect = 2e-77
Identities = 133/186 (71%), Positives = 159/186 (85%), Gaps = 1/186 (0%)
Frame = +2
Query: 284 GLPHRDATDDQVTIDSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILG 463
G+ +RD TDD+VT+++A AI K+ VG+KCATITPDE RVEEFKLKKMWLSPNGTIRNILG
Sbjct: 101 GIEYRDQTDDKVTVEAAEAIKKYGVGVKCATITPDEARVEEFKLKKMWLSPNGTIRNILG 160
Query: 464 GTVFREPILCQSIPRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTRDGTTE 643
GTVFREPI+ +IPR+VPGWTKPI+IGRHA GDQY+A D V+P PGK+ELVYT +G E
Sbjct: 161 GTVFREPIVIPAIPRLVPGWTKPIIIGRHAFGDQYRATDRVIPGPGKLELVYTPANGQPE 220
Query: 644 RRVLYDFKT-PGVAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTILKRYDGRFKD 820
+YDF++ GVAM MYNTD+SIR FAHSSF++AL K PLY+STKNTILKRYDGRFKD
Sbjct: 221 SVQVYDFQSGGGVAMSMYNTDDSIRGFAHSSFKMALLKGLPLYMSTKNTILKRYDGRFKD 280
Query: 821 IFEXVF 838
IF+ ++
Sbjct: 281 IFQEIY 286
>UniRef50_A2WMU2 Cluster: Putative uncharacterized protein; n=5;
Eukaryota|Rep: Putative uncharacterized protein - Oryza
sativa subsp. indica (Rice)
Length = 475
Score = 289 bits (708), Expect = 8e-77
Identities = 141/235 (60%), Positives = 171/235 (72%), Gaps = 18/235 (7%)
Frame = +2
Query: 179 VVEMDGDEMTRIMWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAILKHNV 358
V GDEMTR++W IK++LIFP++ +D Y+DLGLP+RDAT D+VTI+SA A LK+NV
Sbjct: 37 VTRNSGDEMTRVIWKWIKDKLIFPFLDLDIKYYDLGLPNRDATGDKVTIESAEATLKYNV 96
Query: 359 GIKCATITP------------------DEQRVEEFKLKKMWLSPNGTIRNILGGTVFREP 484
IKCATITP DE RV+EF L MW SPNGTIRNIL GTVFREP
Sbjct: 97 AIKCATITPVLDTQFKFDFGRTIHEPTDEGRVKEFNLSAMWKSPNGTIRNILNGTVFREP 156
Query: 485 ILCQSIPRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTRDGTTERRVLYDF 664
I+C++IPR+VPGW KPI IGRHA GDQY+A D V+ PGK++LV+ R+ E V
Sbjct: 157 IICKNIPRLVPGWIKPICIGRHAFGDQYRATDTVIKGPGKLKLVFDGREEQIELDVFNFT 216
Query: 665 KTPGVAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFE 829
GVA+ MYNTDESI +FA +S +A QK+WPLYLSTKNTILK+YDGRFKDIF+
Sbjct: 217 GAGGVALSMYNTDESIWAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQ 271
>UniRef50_A5ZVX5 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus obeum ATCC 29174|Rep: Putative
uncharacterized protein - Ruminococcus obeum ATCC 29174
Length = 417
Score = 267 bits (654), Expect = 3e-70
Identities = 121/228 (53%), Positives = 162/228 (71%)
Frame = +2
Query: 155 KRVVAAKPVVEMDGDEMTRIMWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSA 334
+++ P+VEMDGDEMTRI+W IK+ L+ P++ ++ Y+DLGL +R+ TDDQVTID+A
Sbjct: 17 EKIQMTTPLVEMDGDEMTRILWKMIKDELLLPFIDLNTEYYDLGLNYRNETDDQVTIDAA 76
Query: 335 HAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVV 514
A K+ V +KCATITP+ R++E+ LKKM+ SPNGTIR IL GTVFR PI+ + I V
Sbjct: 77 EATKKYGVAVKCATITPNHARMDEYDLKKMYKSPNGTIRAILDGTVFRAPIVVKGIEPCV 136
Query: 515 PGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTRDGTTERRVLYDFKTPGVAMGMY 694
W KPI + RHA+GD YK + + KPGKVELVYT+ DG +R ++ +FK PGVAMGM+
Sbjct: 137 RNWKKPITLARHAYGDIYKNTEMYIDKPGKVELVYTSEDGEEKRSLVQEFKAPGVAMGMH 196
Query: 695 NTDESIRSFAHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEXVF 838
N SI SFA S F AL K ++ K+TI K YD +FK++F+ VF
Sbjct: 197 NMTASIESFARSCFNYALDTKQDVWFGAKDTISKTYDAKFKEVFQTVF 244
>UniRef50_A5N5L9 Cluster: Idh; n=2; Bacteria|Rep: Idh - Clostridium
kluyveri DSM 555
Length = 401
Score = 260 bits (636), Expect = 4e-68
Identities = 119/221 (53%), Positives = 161/221 (72%)
Frame = +2
Query: 176 PVVEMDGDEMTRIMWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAILKHN 355
P+VEMDGDEMTRI+W IKE L+ PY+ + Y+DLGL R+ T+D++TI++A+AI K+
Sbjct: 10 PLVEMDGDEMTRIIWKMIKELLLEPYIDLKTEYYDLGLVKRNETNDEITIEAANAIKKYG 69
Query: 356 VGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGWTKPI 535
VG+KCATITP+ +RV+E+ LK MW SPNGTIR IL GTVFR PI+ SI ++ W KPI
Sbjct: 70 VGVKCATITPNAKRVKEYNLKSMWKSPNGTIRAILDGTVFRTPIIVNSIRPLMRTWEKPI 129
Query: 536 VIGRHAHGDQYKAQDFVVPKPGKVELVYTTRDGTTERRVLYDFKTPGVAMGMYNTDESIR 715
+ RHA+GD Y+ ++ V +PGK+ELV+T+ G R+ L+ F PGV MGM+N D+SI
Sbjct: 130 TVARHAYGDVYRDVEYKVEEPGKMELVFTSEKGEETRQTLHVFNGPGVVMGMHNLDKSIE 189
Query: 716 SFAHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEXVF 838
SFA S F AL L+ ++K+TI K YD RFKDIF+ ++
Sbjct: 190 SFARSCFNYALDMNQNLWFASKDTISKTYDHRFKDIFQEIY 230
>UniRef50_UPI0000F1EC8D Cluster: PREDICTED: similar to Isocitrate
dehydrogenase 1 (NADP+), soluble; n=2; Danio rerio|Rep:
PREDICTED: similar to Isocitrate dehydrogenase 1
(NADP+), soluble - Danio rerio
Length = 206
Score = 220 bits (538), Expect = 3e-56
Identities = 95/134 (70%), Positives = 119/134 (88%)
Frame = +2
Query: 164 VAAKPVVEMDGDEMTRIMWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAI 343
+ A VVEM GDEMTR++W IKE+LIFPY+++D +DLG+ +RDATDD+VT+++A A+
Sbjct: 12 IKAGSVVEMQGDEMTRVIWELIKEKLIFPYLELDLHSYDLGMENRDATDDKVTVEAAEAV 71
Query: 344 LKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGW 523
++NVGIKCATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+VPGW
Sbjct: 72 RRYNVGIKCATITPDEKRVEEFKLKQMWRSPNGTIRNILGGTVFREAIICKNIPRLVPGW 131
Query: 524 TKPIVIGRHAHGDQ 565
KPI+IGRHAHGDQ
Sbjct: 132 IKPIIIGRHAHGDQ 145
>UniRef50_A2XVE4 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. indica (Rice)
Length = 371
Score = 105 bits (252), Expect(2) = 4e-34
Identities = 46/62 (74%), Positives = 54/62 (87%)
Frame = +2
Query: 653 LYDFKTPGVAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEX 832
+Y+FK PGVA+ MYN DESIR+FA SS +AL KKWPLYLSTKNTILK+YDGRFKDIF+
Sbjct: 44 VYNFKGPGVALSMYNVDESIRAFAESSMAMALSKKWPLYLSTKNTILKKYDGRFKDIFQE 103
Query: 833 VF 838
V+
Sbjct: 104 VY 105
Score = 78.2 bits (184), Expect = 2e-13
Identities = 34/45 (75%), Positives = 40/45 (88%)
Frame = +2
Query: 704 ESIRSFAHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEXVF 838
+SIR+FA SS +AL KKWPLYLSTKNTILK+YDGRFKDIF+ V+
Sbjct: 157 QSIRAFAESSMAMALSKKWPLYLSTKNTILKKYDGRFKDIFQEVY 201
Score = 62.9 bits (146), Expect(2) = 4e-34
Identities = 27/40 (67%), Positives = 33/40 (82%), Gaps = 2/40 (5%)
Frame = +2
Query: 422 MWLSPNGTIRNILGGTVFREPILCQSIPRV--VPGWTKPI 535
MW SPNGTIRNIL GTVFREPILC+++PR+ VP +P+
Sbjct: 1 MWRSPNGTIRNILNGTVFREPILCKNVPRILSVPDGAEPV 40
>UniRef50_Q2K7T8 Cluster: NADP-dependent isocitrate dehydrogenase
protein; n=1; Rhizobium etli CFN 42|Rep: NADP-dependent
isocitrate dehydrogenase protein - Rhizobium etli
(strain CFN 42 / ATCC 51251)
Length = 437
Score = 114 bits (275), Expect = 2e-24
Identities = 71/214 (33%), Positives = 111/214 (51%)
Frame = -3
Query: 826 ENVFETTIVTFQNGILRRQV*RPFFL*SYLKTGMGKGPNRFVGIVHAHSNARSFKII*YT 647
E+V E ++ ++G+L RQV RPF + G G+ +RFV +VH H NA + ++
Sbjct: 198 EDVLEAAVIGLEDGVLGRQVDRPFAHQAVHHRGAGEFADRFVEVVHGHGNAGARRVEDLL 257
Query: 646 PLCRTISCSVNKFNLSGFRYNKILRLVLVAVRMTAYHNRFRPTRHNPRDTLTQYRFAEYC 467
+ L+ ++ VLVA +TA +R RP + R+ R AE
Sbjct: 258 LDDGAVFTDELDRQLALAGELEVGCAVLVAESVTADDDRLRPAGNEARNVAADDRLAEDD 317
Query: 466 TAQNVTDRSVRA*PHFLQLELFYSLFIRCDSSAFDAHIML*NGMR*VDGDLIISGVTMRE 287
A+NV+DR+VRA PHFL++E + FIR D A D + +G+ VD L++ GV + +
Sbjct: 318 AAENVSDRAVRALPHFLEIEFLDAGFIRRDRCALDTDAVFLDGVGGVDRHLVVGGVAIFD 377
Query: 286 AQVKVKTIHLNIWKYQSLFDLSPHDACHLITIHL 185
+V + I + I Q + D P DACH I + +
Sbjct: 378 REVVIVDIEVEIRMDQLILDELPDDACHFIAVEI 411
>UniRef50_A3K670 Cluster: NADP-dependent isocitrate dehydrogenase
protein; n=2; Rhodobacteraceae|Rep: NADP-dependent
isocitrate dehydrogenase protein - Sagittula stellata
E-37
Length = 459
Score = 114 bits (275), Expect = 2e-24
Identities = 73/214 (34%), Positives = 107/214 (50%)
Frame = -3
Query: 826 ENVFETTIVTFQNGILRRQV*RPFFL*SYLKTGMGKGPNRFVGIVHAHSNARSFKII*YT 647
E V E +V +NG+L RQV RP + ++ G GK +R V +VHAH + +++
Sbjct: 229 EQVLEPPVVGLENGVLGRQVHRPAQRQTVVQRGAGKVADRLVLVVHAHVDPGIGRVVDLA 288
Query: 646 PLCRTISCSVNKFNLSGFRYNKILRLVLVAVRMTAYHNRFRPTRHNPRDTLTQYRFAEYC 467
+ L+ +I LVLVA + A+H+ P RH R R AE
Sbjct: 289 LDHLAVGAFPFHRQLARRGEVEIRGLVLVAEGVPAHHDGRGPARHEARHVAADDRLAEDD 348
Query: 466 TAQNVTDRSVRA*PHFLQLELFYSLFIRCDSSAFDAHIML*NGMR*VDGDLIISGVTMRE 287
AQ+V DR+V PH L+ E +L +R D AFD L VDGDL+ V + +
Sbjct: 349 AAQDVADRAVGRLPHLLETEFLDTLLVRGDRRAFDRDANLLRLFGGVDGDLVPGPVPLLD 408
Query: 286 AQVKVKTIHLNIWKYQSLFDLSPHDACHLITIHL 185
++ VK + + + + Q D SPHDA HL+ +HL
Sbjct: 409 PEIVVKQVQVEVRQDQLFLDESPHDAGHLVAVHL 442
>UniRef50_Q5DBI8 Cluster: SJCHGC09598 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC09598 protein - Schistosoma
japonicum (Blood fluke)
Length = 129
Score = 113 bits (271), Expect = 7e-24
Identities = 59/87 (67%), Positives = 66/87 (75%)
Frame = -1
Query: 486 IGSRNTVPPKMLRIVPFGLSHIFFNLNSSTLCSSGVIVAHLMPTLCFRMACAESMVT*SS 307
+GSR TVPP++LRIVPFG SHIFF LNS T CSSGV+VAHL+PTL F +A A S+VT S
Sbjct: 1 MGSRKTVPPRILRIVPFGDSHIFFKLNSLTRCSSGVMVAHLIPTLYFLIASAPSIVTWSL 60
Query: 306 VASRCGRPKSK*RQSTLTYGNISLSLI 226
V SR GRPKSK QST GNIS I
Sbjct: 61 VRSRLGRPKSKYLQSTSINGNISCCFI 87
>UniRef50_A4VDP7 Cluster: Putative uncharacterized protein; n=1;
Tetrahymena thermophila SB210|Rep: Putative
uncharacterized protein - Tetrahymena thermophila SB210
Length = 141
Score = 94.7 bits (225), Expect = 3e-18
Identities = 55/91 (60%), Positives = 63/91 (69%)
Frame = -1
Query: 456 MLRIVPFGLSHIFFNLNSSTLCSSGVIVAHLMPTLCFRMACAESMVT*SSVASRCGRPKS 277
MLRIVP G HIF +LNS T SS VIVAHL+PTLC R+A A S VT S VASR +S
Sbjct: 1 MLRIVPLGEGHIFLSLNSLTRASSAVIVAHLIPTLCSRIAQAASKVTQSLVASRFSIERS 60
Query: 276 K*RQSTLTYGNISLSLILAHMMRVISSPSIS 184
+ S GN+SLSLI+ M+RVISSPS S
Sbjct: 61 QYLISAEINGNMSLSLIIFQMIRVISSPSKS 91
>UniRef50_A3JDN6 Cluster: Isocitrate dehydrogenase; n=5;
Gammaproteobacteria|Rep: Isocitrate dehydrogenase -
Marinobacter sp. ELB17
Length = 582
Score = 92.3 bits (219), Expect = 1e-17
Identities = 60/239 (25%), Positives = 114/239 (47%), Gaps = 12/239 (5%)
Frame = +2
Query: 158 RVVAAKPVVEMDGDEMTRIMWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAH 337
++ P+V + GDEM ++ + +I ++ + + ++ + DL HR T+ QV ++
Sbjct: 4 KIQVESPLVILHGDEMAQVAFEEILKKFVTTRLAIELIEIDLSAEHRFLTNGQVIFEAIE 63
Query: 338 AILKHNVGIKCATITPDEQRVEEFKLKKMWL-----------SPNGTIRNILGGTVFREP 484
A+ K+ VG+K A +T + ++++ K L SPNG IR +GG + RE
Sbjct: 64 ALKKYGVGVKNAGMTVNREQLDAMLEKHPELSQSRLDPLATKSPNGAIRKGIGGNITRED 123
Query: 485 ILCQSIPRVVPGW-TKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTRDGTTERRVLYD 661
I Q++ P W + I + +G + + + G V+L++ + G D
Sbjct: 124 IQFQNLRVRKPDWIDRDIDVDTMDNGGIKDSYNELSSSTGVVKLLFVGKSGNPVELHRRD 183
Query: 662 FKTPGVAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEXVF 838
K + N ++++AH FQ A+ +K YL K+T++ YDG + E ++
Sbjct: 184 VKKGDPWLLATNDIADVKAWAHRFFQRAIDEKRDAYLGLKDTVIAGYDGVMRAAIEAIY 242
>UniRef50_Q00WM7 Cluster: COG0538: Isocitrate dehydrogenases; n=3;
Ostreococcus|Rep: COG0538: Isocitrate dehydrogenases -
Ostreococcus tauri
Length = 429
Score = 90.2 bits (214), Expect = 6e-17
Identities = 75/237 (31%), Positives = 111/237 (46%), Gaps = 7/237 (2%)
Frame = +2
Query: 149 TAKRVVAAKPVVEMDGDEMTRIMWAKIKERLIFPYVKVDCLY-FDLGLPHRDATDDQVTI 325
TA + A P+V + G+EMT + I+ R I P V V FDL +RD T+D+V
Sbjct: 21 TASSKITAAPMVYVRGEEMTAYVMDLIRSRWIEPRVDVGGWETFDLRAKNRDDTEDRVLR 80
Query: 326 DSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGG-TVFREPILCQSI 502
D A + K T+TP +V+ L+K W SPNG +R G T+ R+ I I
Sbjct: 81 DVIEAGKRIKAIFKEPTVTPTADQVKRLGLRKSWGSPNGAMRRGWNGITISRDTI---HI 137
Query: 503 PRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTRDG-TTERRVLYDFK---- 667
V G+ KP++ RHA G +Y A V K GK+ +T +G + V+ D +
Sbjct: 138 DGVELGYKKPVLFERHAVGGEYSAGYKNVGK-GKLTTTFTPSEGPDAGKTVVVDEREIVD 196
Query: 668 TPGVAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEXVF 838
+ +N +++ A F L+ K Y+ TK T+ K + F I VF
Sbjct: 197 EEAAVVTYHNPYDNVHDLARFFFGRCLEAKVTPYVVTKKTVFK-WQEPFWQIMRTVF 252
>UniRef50_Q4VCC2 Cluster: Isocitrate dehydrogenase; n=4;
Eukaryota|Rep: Isocitrate dehydrogenase - Saltugilia
latimeri
Length = 158
Score = 79.4 bits (187), Expect = 1e-13
Identities = 35/47 (74%), Positives = 40/47 (85%)
Frame = +2
Query: 698 TDESIRSFAHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEXVF 838
TDESI SFA +S A +KKWPLYLSTKNTILK+YDGRFKDIF+ V+
Sbjct: 1 TDESIYSFAEASMTTAYEKKWPLYLSTKNTILKKYDGRFKDIFQEVY 47
>UniRef50_Q67N12 Cluster: 3-isopropylmalate dehydrogenase; n=5;
Bacteria|Rep: 3-isopropylmalate dehydrogenase -
Symbiobacterium thermophilum
Length = 357
Score = 51.2 bits (117), Expect = 3e-05
Identities = 42/138 (30%), Positives = 70/138 (50%), Gaps = 3/138 (2%)
Frame = +2
Query: 179 VVEMDGDEMTRIMWAKIKERLIFPYV---KVDCLYFDLGLPHRDATDDQVTIDSAHAILK 349
+V ++GD+ + + + RL+ P V + + +DL L +R AT ++V ++A A+ +
Sbjct: 7 IVVLEGDQTGQELLEEAV-RLLSPDVIGLPLHLVRYDLSLENRRATSNRVVYEAAAAMRE 65
Query: 350 HNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGWTK 529
H G+K ATITP E R + SPN +R + GTV + G T
Sbjct: 66 HGYGLKAATITP-EGRGDVG-------SPNAILRREIDGTVILRTGRPLPGVETIGGITA 117
Query: 530 PIVIGRHAHGDQYKAQDF 583
PI + R A D Y+A+++
Sbjct: 118 PIAVVRMATEDAYEAKEW 135
>UniRef50_Q40658 Cluster: Isocitrate dehydrogenase; n=1; Oryza
sativa|Rep: Isocitrate dehydrogenase - Oryza sativa
(Rice)
Length = 61
Score = 42.7 bits (96), Expect = 0.011
Identities = 16/25 (64%), Positives = 21/25 (84%)
Frame = +2
Query: 191 DGDEMTRIMWAKIKERLIFPYVKVD 265
DGDEMTRI W IK++LIFP++ +D
Sbjct: 35 DGDEMTRIFWQSIKDKLIFPFLDLD 59
>UniRef50_A0KSD7 Cluster: Putative uncharacterized protein; n=2;
Proteobacteria|Rep: Putative uncharacterized protein -
Shewanella sp. (strain ANA-3)
Length = 112
Score = 33.9 bits (74), Expect = 5.1
Identities = 15/52 (28%), Positives = 27/52 (51%)
Frame = +2
Query: 377 ITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGWTKP 532
+T ++ VEE +++MW+ G I NI G + +P + I + W +P
Sbjct: 53 VTENDAGVEEVNVERMWVIVKGRIDNIYRGQLDNDPYCTEEIRSGMEVWFQP 104
>UniRef50_O17998 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 312
Score = 33.5 bits (73), Expect = 6.8
Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Frame = +2
Query: 185 EMDGDEMTRIM-WAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAILKHNVG 361
EMD D +T++ W +IK LI ++ L L LP T +TI + + KH +G
Sbjct: 170 EMDCDGLTKLPHWKRIKSLLIEGFIVSAPLEHFLHLPEVTITMQSITIFNLKLLKKHFLG 229
Query: 362 IK 367
+K
Sbjct: 230 LK 231
>UniRef50_Q09277 Cluster: Putative uncharacterized protein F40H6.5;
n=1; Caenorhabditis elegans|Rep: Putative
uncharacterized protein F40H6.5 - Caenorhabditis elegans
Length = 1288
Score = 33.5 bits (73), Expect = 6.8
Identities = 24/80 (30%), Positives = 38/80 (47%), Gaps = 2/80 (2%)
Frame = +2
Query: 41 HEQW*IHEQYRNMANTSTTKILKCVNQFASLTRNYGTA-KRVVAAKPVVEM-DGDEMTRI 214
++QW I N NT+ + KC++ F +NYG KR+V ++E+ D +T
Sbjct: 730 YQQWTIDTVQMNYQNTNLKYLPKCISIF---QKNYGDLNKRMVNFARIMEVGDNITITGH 786
Query: 215 MWAKIKERLIFPYVKVDCLY 274
+W E YV +D Y
Sbjct: 787 IWQNASESTFNLYVGMDPKY 806
>UniRef50_Q0HEG1 Cluster: Conserved hypothetical biogenesis protein
MshI precursor; n=6; Shewanella|Rep: Conserved
hypothetical biogenesis protein MshI precursor -
Shewanella sp. (strain MR-4)
Length = 292
Score = 33.1 bits (72), Expect = 8.9
Identities = 25/103 (24%), Positives = 46/103 (44%), Gaps = 1/103 (0%)
Frame = +2
Query: 44 EQW*IHEQYRNMANTSTTKILKCVNQFA-SLTRNYGTAKRVVAAKPVVEMDGDEMTRIMW 220
EQW +E +N + ++ A + + G + +VA KP V D DE+++ +
Sbjct: 42 EQWVSYELQQNQWQQAFAELANAFPHAALQIVLSSGRYQLLVADKPNV--DSDELSQALL 99
Query: 221 AKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAILK 349
IK+ + P ++ YF+ LP V D A+++
Sbjct: 100 WSIKDMVTIPVPQIHLDYFESPLPSNKLNVAVVDKDKLRAMVQ 142
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 862,874,470
Number of Sequences: 1657284
Number of extensions: 18066780
Number of successful extensions: 43299
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 41898
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 43286
length of database: 575,637,011
effective HSP length: 100
effective length of database: 409,908,611
effective search space used: 73373641369
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -