Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P05_F_F14
(600 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
L76937-1|AAC41981.1| 1432|Homo sapiens protein ( Homo sapiens We... 72 2e-12
AY818673-1|AAX21098.1| 1432|Homo sapiens Werner syndrome helicas... 72 2e-12
AY442327-1|AAR05448.1| 1432|Homo sapiens Werner syndrome protein. 72 2e-12
AF181897-1|AAF06162.1| 1432|Homo sapiens WRN protein. 72 2e-12
AF091214-1|AAC63361.1| 1432|Homo sapiens WRN protein. 72 2e-12
BC001962-1|AAH01962.1| 496|Homo sapiens exonuclease 3'-5' domai... 58 3e-08
AK001600-1|BAA91781.1| 496|Homo sapiens protein ( Homo sapiens ... 58 3e-08
Z26652-1|CAA81393.1| 993|Homo sapiens FLT3 receptor tyrosine ki... 38 0.020
U02687-1|AAA18947.1| 993|Homo sapiens serine/threonine protein ... 38 0.020
BC126350-1|AAI26351.1| 993|Homo sapiens fms-related tyrosine ki... 38 0.020
BC036028-1|AAH36028.1| 596|Homo sapiens FLT3 protein protein. 38 0.020
AL591024-3|CAH70634.1| 996|Homo sapiens fms-related tyrosine ki... 38 0.020
AL445262-1|CAI17231.1| 996|Homo sapiens fms-related tyrosine ki... 38 0.020
AL356915-1|CAI12447.1| 996|Homo sapiens fms-related tyrosine ki... 38 0.020
M74096-1|AAA51565.1| 430|Homo sapiens long chain acyl-CoA dehyd... 29 9.4
BC064549-1|AAH64549.1| 430|Homo sapiens acyl-Coenzyme A dehydro... 29 9.4
BC039063-1|AAH39063.1| 430|Homo sapiens acyl-Coenzyme A dehydro... 29 9.4
AL135785-2|CAD13246.1| 517|Homo sapiens aldehyde dehydrogenase ... 29 9.4
AC006994-2|AAY14881.1| 430|Homo sapiens unknown protein. 29 9.4
>L76937-1|AAC41981.1| 1432|Homo sapiens protein ( Homo sapiens
Werner syndrome gene, complete cds. ).
Length = 1432
Score = 71.7 bits (168), Expect = 2e-12
Identities = 41/126 (32%), Positives = 66/126 (52%), Gaps = 3/126 (2%)
Frame = +1
Query: 205 RKSRFLDAVNAFSYINIKIVTNERN-CDEAVNELRRRCCDYNALGFDCEW--VTDHGKRN 375
RKS F D + + + + + + C ++ D + +GFD EW + + GK
Sbjct: 36 RKSVFEDDLPFLEFTGSIVYSYDASDCSFLSEDISMSLSDGDVVGFDMEWPPLYNRGKLG 95
Query: 376 PVALVQLSSSDGLCCLFRLSSMETIPNSLKDLLEDEKIYKVGVXASDDGKYLFQDYSVKL 555
VAL+QL S+ C LF +SSM P LK LLE++ + K GV D L +D+ +KL
Sbjct: 96 KVALIQLCVSESKCYLFHVSSMSVFPQGLKMLLENKAVKKAGVGIEGDQWKLLRDFDIKL 155
Query: 556 KSTLDV 573
K+ +++
Sbjct: 156 KNFVEL 161
>AY818673-1|AAX21098.1| 1432|Homo sapiens Werner syndrome helicase
protein.
Length = 1432
Score = 71.7 bits (168), Expect = 2e-12
Identities = 41/126 (32%), Positives = 66/126 (52%), Gaps = 3/126 (2%)
Frame = +1
Query: 205 RKSRFLDAVNAFSYINIKIVTNERN-CDEAVNELRRRCCDYNALGFDCEW--VTDHGKRN 375
RKS F D + + + + + + C ++ D + +GFD EW + + GK
Sbjct: 36 RKSVFEDDLPFLEFTGSIVYSYDASDCSFLSEDISMSLSDGDVVGFDMEWPPLYNRGKLG 95
Query: 376 PVALVQLSSSDGLCCLFRLSSMETIPNSLKDLLEDEKIYKVGVXASDDGKYLFQDYSVKL 555
VAL+QL S+ C LF +SSM P LK LLE++ + K GV D L +D+ +KL
Sbjct: 96 KVALIQLCVSESKCYLFHVSSMSVFPQGLKMLLENKAVKKAGVGIEGDQWKLLRDFDIKL 155
Query: 556 KSTLDV 573
K+ +++
Sbjct: 156 KNFVEL 161
>AY442327-1|AAR05448.1| 1432|Homo sapiens Werner syndrome protein.
Length = 1432
Score = 71.7 bits (168), Expect = 2e-12
Identities = 41/126 (32%), Positives = 66/126 (52%), Gaps = 3/126 (2%)
Frame = +1
Query: 205 RKSRFLDAVNAFSYINIKIVTNERN-CDEAVNELRRRCCDYNALGFDCEW--VTDHGKRN 375
RKS F D + + + + + + C ++ D + +GFD EW + + GK
Sbjct: 36 RKSVFEDDLPFLEFTGSIVYSYDASDCSFLSEDISMSLSDGDVVGFDMEWPPLYNRGKLG 95
Query: 376 PVALVQLSSSDGLCCLFRLSSMETIPNSLKDLLEDEKIYKVGVXASDDGKYLFQDYSVKL 555
VAL+QL S+ C LF +SSM P LK LLE++ + K GV D L +D+ +KL
Sbjct: 96 KVALIQLCVSESKCYLFHVSSMSVFPQGLKMLLENKAVKKAGVGIEGDQWKLLRDFDIKL 155
Query: 556 KSTLDV 573
K+ +++
Sbjct: 156 KNFVEL 161
>AF181897-1|AAF06162.1| 1432|Homo sapiens WRN protein.
Length = 1432
Score = 71.7 bits (168), Expect = 2e-12
Identities = 41/126 (32%), Positives = 66/126 (52%), Gaps = 3/126 (2%)
Frame = +1
Query: 205 RKSRFLDAVNAFSYINIKIVTNERN-CDEAVNELRRRCCDYNALGFDCEW--VTDHGKRN 375
RKS F D + + + + + + C ++ D + +GFD EW + + GK
Sbjct: 36 RKSVFEDDLPFLEFTGSIVYSYDASDCSFLSEDISMSLSDGDVVGFDMEWPPLYNRGKLG 95
Query: 376 PVALVQLSSSDGLCCLFRLSSMETIPNSLKDLLEDEKIYKVGVXASDDGKYLFQDYSVKL 555
VAL+QL S+ C LF +SSM P LK LLE++ + K GV D L +D+ +KL
Sbjct: 96 KVALIQLCVSESKCYLFHVSSMSVFPQGLKMLLENKAVKKAGVGIEGDQWKLLRDFDIKL 155
Query: 556 KSTLDV 573
K+ +++
Sbjct: 156 KNFVEL 161
>AF091214-1|AAC63361.1| 1432|Homo sapiens WRN protein.
Length = 1432
Score = 71.7 bits (168), Expect = 2e-12
Identities = 41/126 (32%), Positives = 66/126 (52%), Gaps = 3/126 (2%)
Frame = +1
Query: 205 RKSRFLDAVNAFSYINIKIVTNERN-CDEAVNELRRRCCDYNALGFDCEW--VTDHGKRN 375
RKS F D + + + + + + C ++ D + +GFD EW + + GK
Sbjct: 36 RKSVFEDDLPFLEFTGSIVYSYDASDCSFLSEDISMSLSDGDVVGFDMEWPPLYNRGKLG 95
Query: 376 PVALVQLSSSDGLCCLFRLSSMETIPNSLKDLLEDEKIYKVGVXASDDGKYLFQDYSVKL 555
VAL+QL S+ C LF +SSM P LK LLE++ + K GV D L +D+ +KL
Sbjct: 96 KVALIQLCVSESKCYLFHVSSMSVFPQGLKMLLENKAVKKAGVGIEGDQWKLLRDFDIKL 155
Query: 556 KSTLDV 573
K+ +++
Sbjct: 156 KNFVEL 161
>BC001962-1|AAH01962.1| 496|Homo sapiens exonuclease 3'-5'
domain-like 2 protein.
Length = 496
Score = 57.6 bits (133), Expect = 3e-08
Identities = 29/67 (43%), Positives = 41/67 (61%), Gaps = 4/67 (5%)
Frame = +1
Query: 394 LSSSDGLCCLFRLSSM----ETIPNSLKDLLEDEKIYKVGVXASDDGKYLFQDYSVKLKS 561
++S GLC L RL + +T+P +L D+L D I KVGV S+D L QDY + ++
Sbjct: 1 MASPSGLCVLVRLPKLICGGKTLPRTLLDILADGTILKVGVGCSEDASKLLQDYGLVVRG 60
Query: 562 TLDVRYL 582
LD+RYL
Sbjct: 61 CLDLRYL 67
>AK001600-1|BAA91781.1| 496|Homo sapiens protein ( Homo sapiens
cDNA FLJ10738 fis, clone NT2RP3001427, weakly similar to
WERNER SYNDROME HELICASE HOMOLOG. ).
Length = 496
Score = 57.6 bits (133), Expect = 3e-08
Identities = 29/67 (43%), Positives = 41/67 (61%), Gaps = 4/67 (5%)
Frame = +1
Query: 394 LSSSDGLCCLFRLSSM----ETIPNSLKDLLEDEKIYKVGVXASDDGKYLFQDYSVKLKS 561
++S GLC L RL + +T+P +L D+L D I KVGV S+D L QDY + ++
Sbjct: 1 MASPSGLCVLVRLPKLICGGKTLPRTLLDILADGTILKVGVGCSEDASKLLQDYGLVVRG 60
Query: 562 TLDVRYL 582
LD+RYL
Sbjct: 61 CLDLRYL 67
>Z26652-1|CAA81393.1| 993|Homo sapiens FLT3 receptor tyrosine
kinase precursor protein.
Length = 993
Score = 38.3 bits (85), Expect = 0.020
Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 5/94 (5%)
Frame = +1
Query: 277 NCDEAVNELRRRCCDYNALGFDCEWVTDHGKRNPVALVQ----LSSSDGLCCLFRLSSME 444
N EA+ +CC YN+LG CE + + P +Q ++ G+C LF +
Sbjct: 502 NMSEAIKGFLVKCCAYNSLGTSCETILLNSP-GPFPFIQDNISFYATIGVCLLFIVVLTL 560
Query: 445 TIPNSLKDLLE-DEKIYKVGVXASDDGKYLFQDY 543
I + K + ++ V V S D +Y + D+
Sbjct: 561 LICHKYKKQFRYESQLQMVQVTGSSDNEYFYVDF 594
>U02687-1|AAA18947.1| 993|Homo sapiens serine/threonine protein
kinase protein.
Length = 993
Score = 38.3 bits (85), Expect = 0.020
Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 5/94 (5%)
Frame = +1
Query: 277 NCDEAVNELRRRCCDYNALGFDCEWVTDHGKRNPVALVQ----LSSSDGLCCLFRLSSME 444
N EA+ +CC YN+LG CE + + P +Q ++ G+C LF +
Sbjct: 502 NMSEAIKGFLVKCCAYNSLGTSCETILLNSP-GPFPFIQDNISFYATIGVCLLFIVVLTL 560
Query: 445 TIPNSLKDLLE-DEKIYKVGVXASDDGKYLFQDY 543
I + K + ++ V V S D +Y + D+
Sbjct: 561 LICHKYKKQFRYESQLQMVQVTGSSDNEYFYVDF 594
>BC126350-1|AAI26351.1| 993|Homo sapiens fms-related tyrosine
kinase 3 protein.
Length = 993
Score = 38.3 bits (85), Expect = 0.020
Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 5/94 (5%)
Frame = +1
Query: 277 NCDEAVNELRRRCCDYNALGFDCEWVTDHGKRNPVALVQ----LSSSDGLCCLFRLSSME 444
N EA+ +CC YN+LG CE + + P +Q ++ G+C LF +
Sbjct: 502 NMSEAIKGFLVKCCAYNSLGTSCETILLNSP-GPFPFIQDNISFYATIGVCLLFIVVLTL 560
Query: 445 TIPNSLKDLLE-DEKIYKVGVXASDDGKYLFQDY 543
I + K + ++ V V S D +Y + D+
Sbjct: 561 LICHKYKKQFRYESQLQMVQVTGSSDNEYFYVDF 594
>BC036028-1|AAH36028.1| 596|Homo sapiens FLT3 protein protein.
Length = 596
Score = 38.3 bits (85), Expect = 0.020
Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 5/94 (5%)
Frame = +1
Query: 277 NCDEAVNELRRRCCDYNALGFDCEWVTDHGKRNPVALVQ----LSSSDGLCCLFRLSSME 444
N EA+ +CC YN+LG CE + + P +Q ++ G+C LF +
Sbjct: 502 NMSEAIKGFLVKCCAYNSLGTSCETILLNSP-GPFPFIQDNISFYATIGVCLLFIVVLTL 560
Query: 445 TIPNSLKDLLE-DEKIYKVGVXASDDGKYLFQDY 543
I + K + ++ V V S D +Y + D+
Sbjct: 561 LICHKYKKQFRYESQLQMVQVTGSSDNEYFYVDF 594
>AL591024-3|CAH70634.1| 996|Homo sapiens fms-related tyrosine
kinase 3 protein.
Length = 996
Score = 38.3 bits (85), Expect = 0.020
Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 5/94 (5%)
Frame = +1
Query: 277 NCDEAVNELRRRCCDYNALGFDCEWVTDHGKRNPVALVQ----LSSSDGLCCLFRLSSME 444
N EA+ +CC YN+LG CE + + P +Q ++ G+C LF +
Sbjct: 502 NMSEAIKGFLVKCCAYNSLGTSCETILLNSP-GPFPFIQDNISFYATIGVCLLFIVVLTL 560
Query: 445 TIPNSLKDLLE-DEKIYKVGVXASDDGKYLFQDY 543
I + K + ++ V V S D +Y + D+
Sbjct: 561 LICHKYKKQFRYESQLQMVQVTGSSDNEYFYVDF 594
>AL445262-1|CAI17231.1| 996|Homo sapiens fms-related tyrosine
kinase 3 protein.
Length = 996
Score = 38.3 bits (85), Expect = 0.020
Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 5/94 (5%)
Frame = +1
Query: 277 NCDEAVNELRRRCCDYNALGFDCEWVTDHGKRNPVALVQ----LSSSDGLCCLFRLSSME 444
N EA+ +CC YN+LG CE + + P +Q ++ G+C LF +
Sbjct: 502 NMSEAIKGFLVKCCAYNSLGTSCETILLNSP-GPFPFIQDNISFYATIGVCLLFIVVLTL 560
Query: 445 TIPNSLKDLLE-DEKIYKVGVXASDDGKYLFQDY 543
I + K + ++ V V S D +Y + D+
Sbjct: 561 LICHKYKKQFRYESQLQMVQVTGSSDNEYFYVDF 594
>AL356915-1|CAI12447.1| 996|Homo sapiens fms-related tyrosine
kinase 3 protein.
Length = 996
Score = 38.3 bits (85), Expect = 0.020
Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 5/94 (5%)
Frame = +1
Query: 277 NCDEAVNELRRRCCDYNALGFDCEWVTDHGKRNPVALVQ----LSSSDGLCCLFRLSSME 444
N EA+ +CC YN+LG CE + + P +Q ++ G+C LF +
Sbjct: 502 NMSEAIKGFLVKCCAYNSLGTSCETILLNSP-GPFPFIQDNISFYATIGVCLLFIVVLTL 560
Query: 445 TIPNSLKDLLE-DEKIYKVGVXASDDGKYLFQDY 543
I + K + ++ V V S D +Y + D+
Sbjct: 561 LICHKYKKQFRYESQLQMVQVTGSSDNEYFYVDF 594
>M74096-1|AAA51565.1| 430|Homo sapiens long chain acyl-CoA
dehydrogenase protein.
Length = 430
Score = 29.5 bits (63), Expect = 9.4
Identities = 11/44 (25%), Positives = 24/44 (54%)
Frame = +1
Query: 436 SMETIPNSLKDLLEDEKIYKVGVXASDDGKYLFQDYSVKLKSTL 567
S+ + N +K ++ K++K+G+ A D + F+D + + L
Sbjct: 231 SLFLVENGMKGFIKGRKLHKMGLKAQDTAELFFEDIRLPASALL 274
>BC064549-1|AAH64549.1| 430|Homo sapiens acyl-Coenzyme A
dehydrogenase, long chain protein.
Length = 430
Score = 29.5 bits (63), Expect = 9.4
Identities = 11/44 (25%), Positives = 24/44 (54%)
Frame = +1
Query: 436 SMETIPNSLKDLLEDEKIYKVGVXASDDGKYLFQDYSVKLKSTL 567
S+ + N +K ++ K++K+G+ A D + F+D + + L
Sbjct: 231 SLFLVENGMKGFIKGRKLHKMGLKAQDTAELFFEDIRLPASALL 274
>BC039063-1|AAH39063.1| 430|Homo sapiens acyl-Coenzyme A
dehydrogenase, long chain protein.
Length = 430
Score = 29.5 bits (63), Expect = 9.4
Identities = 11/44 (25%), Positives = 24/44 (54%)
Frame = +1
Query: 436 SMETIPNSLKDLLEDEKIYKVGVXASDDGKYLFQDYSVKLKSTL 567
S+ + N +K ++ K++K+G+ A D + F+D + + L
Sbjct: 231 SLFLVENGMKGFIKGRKLHKMGLKAQDTAELFFEDIRLPASALL 274
>AL135785-2|CAD13246.1| 517|Homo sapiens aldehyde dehydrogenase 1
family, member B1 protein.
Length = 517
Score = 29.5 bits (63), Expect = 9.4
Identities = 14/43 (32%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
Frame = +1
Query: 454 NSLKDLLEDEKIYKVGVXASDDGKYLFQDYSVKLKSTLDV-RY 579
N L DL+E +++Y + D+GK + Y++ L + V RY
Sbjct: 106 NRLADLVERDRVYLASLETLDNGKPFQESYALDLDEVIKVYRY 148
>AC006994-2|AAY14881.1| 430|Homo sapiens unknown protein.
Length = 430
Score = 29.5 bits (63), Expect = 9.4
Identities = 11/44 (25%), Positives = 24/44 (54%)
Frame = +1
Query: 436 SMETIPNSLKDLLEDEKIYKVGVXASDDGKYLFQDYSVKLKSTL 567
S+ + N +K ++ K++K+G+ A D + F+D + + L
Sbjct: 231 SLFLVENGMKGFIKGRKLHKMGLKAQDTAELFFEDIRLPASALL 274
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 74,066,917
Number of Sequences: 237096
Number of extensions: 1353691
Number of successful extensions: 2661
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 2608
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2656
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6297951520
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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