Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P04_F_O11
(798 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AB209722-1|BAD92959.1| 421|Homo sapiens mevalonate kinase varia... 74 5e-13
M88468-1|AAB59362.1| 396|Homo sapiens mevalonate kinase protein. 73 9e-13
BC016140-1|AAH16140.1| 396|Homo sapiens MVK protein protein. 73 9e-13
AF217535-1|AAF82407.1| 396|Homo sapiens mevalonate kinase protein. 73 9e-13
AF217536-1|AAF82406.1| 113|Homo sapiens truncated mevalonate ki... 54 5e-07
AF060511-1|AAG43129.1| 86|Homo sapiens My016 protein protein. 36 0.17
>AB209722-1|BAD92959.1| 421|Homo sapiens mevalonate kinase variant
protein.
Length = 421
Score = 74.1 bits (174), Expect = 5e-13
Identities = 62/171 (36%), Positives = 96/171 (56%), Gaps = 2/171 (1%)
Frame = +3
Query: 231 VSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPA-VHIHLPCVDLQETIP 407
VSAPGKVILHGEH+VV+GK A+AVSL LR+ + ++ PH V ++LP + ++
Sbjct: 33 VSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQ----PHSNGKVDLNLPNIGIKRAWD 88
Query: 408 LEPTVKSLFHPKLAPG-ITGKFSWRLPHKIDHDYHLRRVEEYLHLIKPNFDSLPNNQKNS 584
+ ++SL L G +T S + +++E L P D ++ +
Sbjct: 89 V-ARLQSLDTSFLEQGDVTTPTS----------EQVEKLKEVAGL--P--DDCAVTERLA 133
Query: 585 LRSFLYVFSGIFGSTYLPVKSMDISMGSELTIGAGTGSSASFAVCLAGALI 737
+ +FLY++ I + S+DI + SEL GAG GSSA+++VCLA AL+
Sbjct: 134 VLAFLYLYLSIC-RKQRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALL 183
>M88468-1|AAB59362.1| 396|Homo sapiens mevalonate kinase protein.
Length = 396
Score = 73.3 bits (172), Expect = 9e-13
Identities = 62/171 (36%), Positives = 95/171 (55%), Gaps = 2/171 (1%)
Frame = +3
Query: 231 VSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPA-VHIHLPCVDLQETIP 407
VSAPGKVILHGEH+VV+GK A+AVSL LR+ + ++ PH V + LP + ++
Sbjct: 8 VSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQ----PHSNGKVDLSLPNIGIKRAWD 63
Query: 408 LEPTVKSLFHPKLAPG-ITGKFSWRLPHKIDHDYHLRRVEEYLHLIKPNFDSLPNNQKNS 584
+ ++SL L G +T S + +++E L P D ++ +
Sbjct: 64 V-ARLQSLDTSFLEQGDVTTPTS----------EQVEKLKEVAGL--P--DDCAVTERLA 108
Query: 585 LRSFLYVFSGIFGSTYLPVKSMDISMGSELTIGAGTGSSASFAVCLAGALI 737
+ +FLY++ I + S+DI + SEL GAG GSSA+++VCLA AL+
Sbjct: 109 VLAFLYLYLSIC-RKQRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALL 158
>BC016140-1|AAH16140.1| 396|Homo sapiens MVK protein protein.
Length = 396
Score = 73.3 bits (172), Expect = 9e-13
Identities = 62/171 (36%), Positives = 95/171 (55%), Gaps = 2/171 (1%)
Frame = +3
Query: 231 VSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPA-VHIHLPCVDLQETIP 407
VSAPGKVILHGEH+VV+GK A+AVSL LR+ + ++ PH V + LP + ++
Sbjct: 8 VSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQ----PHSNGKVDLSLPNIGIKRAWD 63
Query: 408 LEPTVKSLFHPKLAPG-ITGKFSWRLPHKIDHDYHLRRVEEYLHLIKPNFDSLPNNQKNS 584
+ ++SL L G +T S + +++E L P D ++ +
Sbjct: 64 V-ARLQSLDTSFLEQGDVTTPTS----------EQVEKLKEVAGL--P--DDCAVTERLA 108
Query: 585 LRSFLYVFSGIFGSTYLPVKSMDISMGSELTIGAGTGSSASFAVCLAGALI 737
+ +FLY++ I + S+DI + SEL GAG GSSA+++VCLA AL+
Sbjct: 109 VLAFLYLYLSIC-RKQRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALL 158
>AF217535-1|AAF82407.1| 396|Homo sapiens mevalonate kinase protein.
Length = 396
Score = 73.3 bits (172), Expect = 9e-13
Identities = 62/171 (36%), Positives = 95/171 (55%), Gaps = 2/171 (1%)
Frame = +3
Query: 231 VSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPA-VHIHLPCVDLQETIP 407
VSAPGKVILHGEH+VV+GK A+AVSL LR+ + ++ PH V + LP + ++
Sbjct: 8 VSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQ----PHSNGKVDLSLPNIGIKRAWD 63
Query: 408 LEPTVKSLFHPKLAPG-ITGKFSWRLPHKIDHDYHLRRVEEYLHLIKPNFDSLPNNQKNS 584
+ ++SL L G +T S + +++E L P D ++ +
Sbjct: 64 V-ARLQSLDTSFLEQGDVTTPTS----------EQVEKLKEVAGL--P--DDCAVTERLA 108
Query: 585 LRSFLYVFSGIFGSTYLPVKSMDISMGSELTIGAGTGSSASFAVCLAGALI 737
+ +FLY++ I + S+DI + SEL GAG GSSA+++VCLA AL+
Sbjct: 109 VLAFLYLYLSIC-RKQRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALL 158
>AF217536-1|AAF82406.1| 113|Homo sapiens truncated mevalonate
kinase protein.
Length = 113
Score = 54.4 bits (125), Expect = 5e-07
Identities = 29/56 (51%), Positives = 40/56 (71%), Gaps = 1/56 (1%)
Frame = +3
Query: 231 VSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPA-VHIHLPCVDLQ 395
VSAPGKVILHGEH+VV+GK A+AVSL LR+ + ++ PH V + LP + ++
Sbjct: 4 VSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQ----PHSNGKVDLSLPNIGIK 55
>AF060511-1|AAG43129.1| 86|Homo sapiens My016 protein protein.
Length = 86
Score = 35.9 bits (79), Expect = 0.17
Identities = 16/21 (76%), Positives = 16/21 (76%)
Frame = +2
Query: 8 LQEELKTIHAFTQKTLTVDQW 70
L EEL IHAF QKTLT DQW
Sbjct: 60 LAEELPHIHAFEQKTLTPDQW 80
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 127,304,811
Number of Sequences: 237096
Number of extensions: 3048533
Number of successful extensions: 6678
Number of sequences better than 10.0: 6
Number of HSP's better than 10.0 without gapping: 6358
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6678
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9813323168
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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