Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P04_F_J22
(718 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q01581 Cluster: Hydroxymethylglutaryl-CoA synthase, cyt... 308 1e-82
UniRef50_A6RGN8 Cluster: Hydroxymethylglutaryl-CoA synthase; n=3... 294 2e-78
UniRef50_Q2UKZ2 Cluster: Hydroxymethylglutaryl-CoA synthase; n=5... 289 5e-77
UniRef50_P54839 Cluster: Hydroxymethylglutaryl-CoA synthase; n=1... 278 9e-74
UniRef50_P54873 Cluster: Hydroxymethylglutaryl-CoA synthase; n=3... 266 4e-70
UniRef50_Q5KJX0 Cluster: Hydroxymethylglutaryl-CoA synthase, put... 254 1e-66
UniRef50_UPI00006CFE45 Cluster: hydroxymethylglutaryl-CoA syntha... 246 4e-64
UniRef50_Q5BWB2 Cluster: SJCHGC04979 protein; n=1; Schistosoma j... 232 7e-60
UniRef50_A0DKI0 Cluster: Chromosome undetermined scaffold_54, wh... 231 1e-59
UniRef50_P54871 Cluster: Hydroxymethylglutaryl-CoA synthase; n=2... 221 1e-56
UniRef50_UPI00005A343B Cluster: PREDICTED: similar to Hydroxymet... 214 2e-54
UniRef50_A2FZ93 Cluster: Hydroxymethylglutaryl-CoA synthase fami... 209 6e-53
UniRef50_Q8SR61 Cluster: 3-HYDROXY-3-METHYLGLUTARYL-CoA SYNTHASE... 161 2e-38
UniRef50_Q1D4I1 Cluster: Hydroxymethylglutaryl-CoA synthase; n=2... 128 1e-28
UniRef50_Q7QQE4 Cluster: GLP_91_15470_16939; n=1; Giardia lambli... 123 5e-27
UniRef50_A0RW92 Cluster: 3-hydroxy-3-methylglutaryl CoA synthase... 109 5e-23
UniRef50_Q5V1G0 Cluster: Hydroxymethylglutaryl-CoA synthase; n=5... 101 2e-20
UniRef50_A0NJ77 Cluster: 3-hydroxy-3-methylglutaryl CoA synthase... 91 3e-17
UniRef50_A5FM54 Cluster: Hydroxymethylglutaryl-CoA synthase; n=2... 87 5e-16
UniRef50_Q88VI4 Cluster: Hydroxymethylglutaryl-CoA synthase; n=4... 85 1e-15
UniRef50_Q9FD82 Cluster: HMG-CoA synthase; n=16; Staphylococcus|... 84 3e-15
UniRef50_A5EUV4 Cluster: Hydroxymethylglutaryl-CoA synthase; n=1... 80 6e-14
UniRef50_Q04AW0 Cluster: 3-hydroxy-3-methylglutaryl CoA synthase... 77 3e-13
UniRef50_A7QFV6 Cluster: Chromosome undetermined scaffold_89, wh... 74 4e-12
UniRef50_Q8L1I3 Cluster: HMG-CoA synthase; n=1; Paracoccus zeaxa... 73 5e-12
UniRef50_A4FIG4 Cluster: Hydroxymethylglutaryl-CoA synthase; n=1... 71 3e-11
UniRef50_Q9FD56 Cluster: HMG-CoA synthase; n=46; Streptococcacea... 68 3e-10
UniRef50_P40830 Cluster: Putative polyketide biosynthesis protei... 62 1e-08
UniRef50_Q767G7 Cluster: HMG-CoA synthase; n=9; Bacteria|Rep: HM... 61 2e-08
UniRef50_A6G7N7 Cluster: Hydroxymethylglutaryl-coenzyme A syntha... 60 7e-08
UniRef50_A6G789 Cluster: Hydroxymethylglutaryl-CoA synthase; n=1... 58 2e-07
UniRef50_Q4QAB9 Cluster: Putative uncharacterized protein; n=5; ... 58 2e-07
UniRef50_UPI000038D51C Cluster: COG3425: 3-hydroxy-3-methylgluta... 53 6e-06
UniRef50_Q1CGN1 Cluster: Hydroxymethylglutaryl-coenzyme A syntha... 50 8e-05
UniRef50_Q6MLJ5 Cluster: 3-oxoacyl-(Acyl-carrier-protein) syntha... 44 0.004
UniRef50_P51196 Cluster: 3-oxoacyl-[acyl-carrier-protein] syntha... 43 0.009
UniRef50_Q81JG0 Cluster: 3-oxoacyl-[acyl-carrier-protein] syntha... 40 0.061
UniRef50_Q1VIJ1 Cluster: 3-hydroxy-3-methylglutaryl-coenzyme A s... 40 0.081
UniRef50_Q97CG9 Cluster: UPF0219 protein TV0132; n=37; cellular ... 39 0.14
UniRef50_A2Z2A6 Cluster: Putative uncharacterized protein; n=2; ... 36 1.00
UniRef50_Q9KET5 Cluster: 3-oxoacyl-[acyl-carrier-protein] syntha... 36 1.3
UniRef50_Q13PK8 Cluster: Putative uncharacterized protein; n=2; ... 35 1.7
UniRef50_A4F133 Cluster: Putative uncharacterized protein; n=1; ... 35 1.7
UniRef50_UPI0000D5795B Cluster: PREDICTED: similar to CG12149-PA... 34 4.0
UniRef50_Q419Z7 Cluster: Beta-ketoacyl-acyl carrier protein synt... 33 5.3
UniRef50_Q6MVD4 Cluster: Related to glucan 1, 4-alpha-glucosidas... 33 5.3
UniRef50_UPI0000E4A4E5 Cluster: PREDICTED: similar to scavenger ... 33 7.0
UniRef50_Q8EY21 Cluster: NADH dehydrogenase; n=4; Leptospira|Rep... 33 7.0
UniRef50_A7LTP0 Cluster: Putative uncharacterized protein; n=1; ... 33 7.0
UniRef50_A4AX52 Cluster: Putative ABC-type transport system, ATP... 33 7.0
UniRef50_A3TWG2 Cluster: Methionine sulfoxide reductase B; n=1; ... 33 7.0
UniRef50_A3J8N4 Cluster: Hydrolase of the alpha/beta superfamily... 33 7.0
UniRef50_Q6K4B4 Cluster: Putative uncharacterized protein OJ1509... 33 7.0
UniRef50_Q6RCQ7 Cluster: SdeD; n=11; Legionella pneumophila|Rep:... 33 9.3
UniRef50_Q0RBP5 Cluster: Putative uncharacterized protein; n=1; ... 33 9.3
UniRef50_A3I6K4 Cluster: Putative uncharacterized protein; n=1; ... 33 9.3
UniRef50_A0Z706 Cluster: Putative uncharacterized protein; n=1; ... 33 9.3
UniRef50_A3BZV3 Cluster: Putative uncharacterized protein; n=1; ... 33 9.3
UniRef50_Q4Y427 Cluster: Putative uncharacterized protein; n=1; ... 33 9.3
>UniRef50_Q01581 Cluster: Hydroxymethylglutaryl-CoA synthase,
cytoplasmic; n=102; Eukaryota|Rep:
Hydroxymethylglutaryl-CoA synthase, cytoplasmic - Homo
sapiens (Human)
Length = 520
Score = 308 bits (755), Expect = 1e-82
Identities = 138/191 (72%), Positives = 166/191 (86%)
Frame = +2
Query: 146 ENVGILAMELYFPSQYVDQTELEKFDEVSTGKYTIGLGQSKMGFCSDREDINSICLTALH 325
++VGI+A+E+YFPSQYVDQ ELEK+D V GKYTIGLGQ+KMGFC+DREDINS+C+T +
Sbjct: 15 KDVGIVALEIYFPSQYVDQAELEKYDGVDAGKYTIGLGQAKMGFCTDREDINSLCMTVVQ 74
Query: 326 RLIDKQKINLHDIGRLEVGTETIIDKSKSVKTFLMTLFAKEGATDIEGIDTTNACYGGTA 505
L+++ ++ IGRLEVGTETIIDKSKSVKT LM LF + G TDIEGIDTTNACYGGTA
Sbjct: 75 NLMERNNLSYDCIGRLEVGTETIIDKSKSVKTNLMQLFEESGNTDIEGIDTTNACYGGTA 134
Query: 506 ALFNAINWVESSSWDGRKAIVVAGDIAVYGKGPARPTGGAGAVAMLIGPDAPLVFDCGVR 685
A+FNA+NW+ESSSWDGR A+VVAGDIAVY G ARPTGG GAVA+LIGP+APL+F+ G+R
Sbjct: 135 AVFNAVNWIESSSWDGRYALVVAGDIAVYATGNARPTGGVGAVALLIGPNAPLIFERGLR 194
Query: 686 ASYMTHAYDFY 718
++M HAYDFY
Sbjct: 195 GTHMQHAYDFY 205
>UniRef50_A6RGN8 Cluster: Hydroxymethylglutaryl-CoA synthase; n=3;
Pezizomycotina|Rep: Hydroxymethylglutaryl-CoA synthase -
Ajellomyces capsulatus NAm1
Length = 475
Score = 294 bits (721), Expect = 2e-78
Identities = 135/196 (68%), Positives = 161/196 (82%)
Frame = +2
Query: 131 MGGKVENVGILAMELYFPSQYVDQTELEKFDEVSTGKYTIGLGQSKMGFCSDREDINSIC 310
M + +N+GI A+E+YFPSQ VDQ ELEKFD VS GKYTIGLGQ+KM FC DREDI S+
Sbjct: 1 MPSRPQNIGIKAIEIYFPSQCVDQAELEKFDGVSQGKYTIGLGQTKMSFCDDREDIYSMS 60
Query: 311 LTALHRLIDKQKINLHDIGRLEVGTETIIDKSKSVKTFLMTLFAKEGATDIEGIDTTNAC 490
LT L L+ K I+ IGRLEVGTETI+DKSKSVK+ LM LFA+ G T++EG+DT NAC
Sbjct: 61 LTTLSSLLRKYSIDPKSIGRLEVGTETILDKSKSVKSVLMQLFAESGNTNVEGVDTVNAC 120
Query: 491 YGGTAALFNAINWVESSSWDGRKAIVVAGDIAVYGKGPARPTGGAGAVAMLIGPDAPLVF 670
YGGT A+FN++NWVESS+WDGR AIVV GDIA+Y KG ARPTGGAG +AMLIGPDAP+VF
Sbjct: 121 YGGTNAIFNSVNWVESSAWDGRDAIVVTGDIALYKKGAARPTGGAGCIAMLIGPDAPIVF 180
Query: 671 DCGVRASYMTHAYDFY 718
+ G+R S++TH YDFY
Sbjct: 181 EPGLRGSHITHEYDFY 196
>UniRef50_Q2UKZ2 Cluster: Hydroxymethylglutaryl-CoA synthase; n=5;
Eukaryota|Rep: Hydroxymethylglutaryl-CoA synthase -
Aspergillus oryzae
Length = 460
Score = 289 bits (709), Expect = 5e-77
Identities = 128/196 (65%), Positives = 159/196 (81%)
Frame = +2
Query: 131 MGGKVENVGILAMELYFPSQYVDQTELEKFDEVSTGKYTIGLGQSKMGFCSDREDINSIC 310
M + +N+G+ A+E+YFP Q V+QTELEKFD VS GKYTIGLGQ+KM FC DREDI S+
Sbjct: 1 MSARPQNIGVKAIEVYFPKQCVEQTELEKFDGVSEGKYTIGLGQTKMSFCDDREDIYSVA 60
Query: 311 LTALHRLIDKQKINLHDIGRLEVGTETIIDKSKSVKTFLMTLFAKEGATDIEGIDTTNAC 490
LT L L K ++ +GRLEVGTET++DKSKSVK+ LM LFA+ G ++EG+D NAC
Sbjct: 61 LTTLSSLFRKYNVDPKSVGRLEVGTETLLDKSKSVKSVLMQLFAESGNFNVEGVDNVNAC 120
Query: 491 YGGTAALFNAINWVESSSWDGRKAIVVAGDIAVYGKGPARPTGGAGAVAMLIGPDAPLVF 670
YGGT A+FN+INW+ESS+WDGR A+VV GDIA+Y +GPARPTGGAG VA+LIGPDAP+VF
Sbjct: 121 YGGTNAVFNSINWLESSAWDGRDAVVVCGDIALYAEGPARPTGGAGCVALLIGPDAPIVF 180
Query: 671 DCGVRASYMTHAYDFY 718
+ G+R SY+TH YDFY
Sbjct: 181 EPGLRGSYVTHTYDFY 196
>UniRef50_P54839 Cluster: Hydroxymethylglutaryl-CoA synthase; n=11;
Ascomycota|Rep: Hydroxymethylglutaryl-CoA synthase -
Saccharomyces cerevisiae (Baker's yeast)
Length = 491
Score = 278 bits (682), Expect = 9e-74
Identities = 134/202 (66%), Positives = 159/202 (78%)
Frame = +2
Query: 113 KQYTVNMGGKVENVGILAMELYFPSQYVDQTELEKFDEVSTGKYTIGLGQSKMGFCSDRE 292
KQ T + +NVGI +++Y P+Q V+Q+ELEKFD VS GKYTIGLGQ+ M F +DRE
Sbjct: 36 KQKTAEQKTRPQNVGIKGIQIYIPTQCVNQSELEKFDGVSQGKYTIGLGQTNMSFVNDRE 95
Query: 293 DINSICLTALHRLIDKQKINLHDIGRLEVGTETIIDKSKSVKTFLMTLFAKEGATDIEGI 472
DI S+ LT L +LI I+ + IGRLEVGTET+IDKSKSVK+ LM LF + TD+EGI
Sbjct: 96 DIYSMSLTVLSKLIKSYNIDTNKIGRLEVGTETLIDKSKSVKSVLMQLFGEN--TDVEGI 153
Query: 473 DTTNACYGGTAALFNAINWVESSSWDGRKAIVVAGDIAVYGKGPARPTGGAGAVAMLIGP 652
DT NACYGGT ALFN++NW+ES++WDGR AIVV GDIA+Y KG ARPTGGAG VAM IGP
Sbjct: 154 DTLNACYGGTNALFNSLNWIESNAWDGRDAIVVCGDIAIYDKGAARPTGGAGTVAMWIGP 213
Query: 653 DAPLVFDCGVRASYMTHAYDFY 718
DAP+VFD VRASYM HAYDFY
Sbjct: 214 DAPIVFD-SVRASYMEHAYDFY 234
>UniRef50_P54873 Cluster: Hydroxymethylglutaryl-CoA synthase; n=31;
Streptophytina|Rep: Hydroxymethylglutaryl-CoA synthase -
Arabidopsis thaliana (Mouse-ear cress)
Length = 461
Score = 266 bits (652), Expect = 4e-70
Identities = 121/191 (63%), Positives = 149/191 (78%)
Frame = +2
Query: 146 ENVGILAMELYFPSQYVDQTELEKFDEVSTGKYTIGLGQSKMGFCSDREDINSICLTALH 325
+NVGILAM++YFP V Q LE D S GKYTIGLGQ + FC++ ED+ S+ A+
Sbjct: 3 KNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQDCLAFCTELEDVISMSFNAVT 62
Query: 326 RLIDKQKINLHDIGRLEVGTETIIDKSKSVKTFLMTLFAKEGATDIEGIDTTNACYGGTA 505
L +K KI+ + IGRLEVG+ET+IDKSKS+KTFLM LF K G TD+EG+D+TNACYGGTA
Sbjct: 63 SLFEKYKIDPNQIGRLEVGSETVIDKSKSIKTFLMQLFEKCGNTDVEGVDSTNACYGGTA 122
Query: 506 ALFNAINWVESSSWDGRKAIVVAGDIAVYGKGPARPTGGAGAVAMLIGPDAPLVFDCGVR 685
AL N +NWVES+SWDGR +V+ D AVY +GPARPTGGA A+AMLIGPDAP+VF+ +R
Sbjct: 123 ALLNCVNWVESNSWDGRYGLVICTDSAVYAEGPARPTGGAAAIAMLIGPDAPIVFESKLR 182
Query: 686 ASYMTHAYDFY 718
AS+M H YDFY
Sbjct: 183 ASHMAHVYDFY 193
>UniRef50_Q5KJX0 Cluster: Hydroxymethylglutaryl-CoA synthase,
putative; n=2; Filobasidiella neoformans|Rep:
Hydroxymethylglutaryl-CoA synthase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 498
Score = 254 bits (623), Expect = 1e-66
Identities = 119/190 (62%), Positives = 143/190 (75%)
Frame = +2
Query: 149 NVGILAMELYFPSQYVDQTELEKFDEVSTGKYTIGLGQSKMGFCSDREDINSICLTALHR 328
NVGI A+E+YFP + + + ELE FD VS GKYT+GLGQ M F D+EDINS+ LT +
Sbjct: 12 NVGIHAIEMYFPKRCISEDELEDFDGVSKGKYTLGLGQKYMAFTDDKEDINSLALTVVSN 71
Query: 329 LIDKQKINLHDIGRLEVGTETIIDKSKSVKTFLMTLFAKEGATDIEGIDTTNACYGGTAA 508
L+ K I+ IGRL+VGTETIIDKSKS KT LM LFA G TDIEGID+ NACYG TAA
Sbjct: 72 LLKKYNIDPRSIGRLDVGTETIIDKSKSTKTLLMDLFAASGNTDIEGIDSKNACYGSTAA 131
Query: 509 LFNAINWVESSSWDGRKAIVVAGDIAVYGKGPARPTGGAGAVAMLIGPDAPLVFDCGVRA 688
LFN +NW++S SWDGR AIV+ GDIA+Y +G ARP GG GA AMLIGPDAPLV + V
Sbjct: 132 LFNTVNWIQSESWDGRNAIVMCGDIAIYKEGGARPVGGMGACAMLIGPDAPLVLE-PVHG 190
Query: 689 SYMTHAYDFY 718
+Y+ + +DFY
Sbjct: 191 TYIANTWDFY 200
>UniRef50_UPI00006CFE45 Cluster: hydroxymethylglutaryl-CoA synthase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
hydroxymethylglutaryl-CoA synthase family protein -
Tetrahymena thermophila SB210
Length = 566
Score = 246 bits (602), Expect = 4e-64
Identities = 117/192 (60%), Positives = 146/192 (76%), Gaps = 1/192 (0%)
Frame = +2
Query: 146 ENVGILAMELYFPSQYVDQTELEKFDEVSTGKYTIGLGQSKMGFCSDREDINSICLTALH 325
+NVGI A+E YFP ++ Q ELE+FD VS GKYTIGLGQ M F ED+NS+ LT +
Sbjct: 4 QNVGIHAIETYFPKTFISQEELEQFDGVSKGKYTIGLGQKCMSFVEPYEDVNSLALTVVQ 63
Query: 326 RLIDKQKINLHDIGRLEVGTETIIDKSKSVKTFLMTLFAKEGATDIEGIDTTNACYGGTA 505
++K KI+ IGRLEVGTET+IDKSKS KT LM LF K G DIEGI T NACYGGTA
Sbjct: 64 NTLEKYKIDPRMIGRLEVGTETLIDKSKSTKTVLMQLFNKYGNHDIEGITTINACYGGTA 123
Query: 506 ALFNAINWVESSSWDGRK-AIVVAGDIAVYGKGPARPTGGAGAVAMLIGPDAPLVFDCGV 682
ALFN + WVESS++DG++ VV D+AVY KGPARPTGGAGA+ M+IGP+AP++ + +
Sbjct: 124 ALFNTLAWVESSAYDGKRLGCVVTVDVAVYKKGPARPTGGAGAICMIIGPNAPIIVE-PI 182
Query: 683 RASYMTHAYDFY 718
R++++ HAYDFY
Sbjct: 183 RSTFIDHAYDFY 194
>UniRef50_Q5BWB2 Cluster: SJCHGC04979 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC04979 protein - Schistosoma
japonicum (Blood fluke)
Length = 247
Score = 232 bits (567), Expect = 7e-60
Identities = 113/176 (64%), Positives = 137/176 (77%)
Frame = +2
Query: 155 GILAMELYFPSQYVDQTELEKFDEVSTGKYTIGLGQSKMGFCSDREDINSICLTALHRLI 334
GI+A+E+YFP YV Q +LE DE GKYT GLGQ+ +GFCS +EDINSICLT + L+
Sbjct: 15 GIIALEVYFPRFYVSQHDLEVADEC-VGKYTQGLGQTSLGFCSMQEDINSICLTVVSNLV 73
Query: 335 DKQKINLHDIGRLEVGTETIIDKSKSVKTFLMTLFAKEGATDIEGIDTTNACYGGTAALF 514
++ I+L IG LEVGTETIIDKSKS KT LM LF G DIEG+D NAC+GGT+ALF
Sbjct: 74 KRENIDLKAIGFLEVGTETIIDKSKSTKTVLMQLFEAAGNFDIEGVDVKNACFGGTSALF 133
Query: 515 NAINWVESSSWDGRKAIVVAGDIAVYGKGPARPTGGAGAVAMLIGPDAPLVFDCGV 682
A+NW+ESS +GR A+VVA DIAVYG+ ARPTGGAGAVA+L+GP+APLV D G+
Sbjct: 134 GALNWLESSYCNGRLALVVAADIAVYGEKSARPTGGAGAVAILLGPNAPLVIDPGL 189
>UniRef50_A0DKI0 Cluster: Chromosome undetermined scaffold_54, whole
genome shotgun sequence; n=11; Eukaryota|Rep: Chromosome
undetermined scaffold_54, whole genome shotgun sequence
- Paramecium tetraurelia
Length = 2056
Score = 231 bits (566), Expect = 1e-59
Identities = 113/193 (58%), Positives = 138/193 (71%)
Frame = +2
Query: 140 KVENVGILAMELYFPSQYVDQTELEKFDEVSTGKYTIGLGQSKMGFCSDREDINSICLTA 319
K NVGI A+E+YFP YV+Q ELE FD VS GKYT+GLGQ M F ED+N++ LT
Sbjct: 2 KAINVGIEAIEIYFPKTYVNQAELELFDNVSQGKYTVGLGQVNMAFVRPFEDVNTMALTV 61
Query: 320 LHRLIDKQKINLHDIGRLEVGTETIIDKSKSVKTFLMTLFAKEGATDIEGIDTTNACYGG 499
+ L++K +IN IGRLEVGTE+++DKSKS KT LM LF T+IEG+ + NACYGG
Sbjct: 62 VTNLLEKNQINPALIGRLEVGTESLLDKSKSTKTTLMRLFGDN--TNIEGVTSINACYGG 119
Query: 500 TAALFNAINWVESSSWDGRKAIVVAGDIAVYGKGPARPTGGAGAVAMLIGPDAPLVFDCG 679
T ALFN INW++S +WDGR +VV DIAVY KG AR TGGAGA+AMLI P+A D
Sbjct: 120 TNALFNTINWMQSEAWDGRYGLVVCTDIAVYAKGSARTTGGAGAIAMLIAPNATFTID-P 178
Query: 680 VRASYMTHAYDFY 718
+R +YM YDFY
Sbjct: 179 IRTTYMKDNYDFY 191
>UniRef50_P54871 Cluster: Hydroxymethylglutaryl-CoA synthase; n=2;
Caenorhabditis|Rep: Hydroxymethylglutaryl-CoA synthase -
Caenorhabditis elegans
Length = 462
Score = 221 bits (540), Expect = 1e-56
Identities = 113/193 (58%), Positives = 139/193 (72%), Gaps = 1/193 (0%)
Frame = +2
Query: 143 VENVGILAMELYFPSQYVDQTELEKFDEVSTGKYTIGLGQSKMGFCSDREDINSICLTAL 322
V +VGI A+ELYFP +VDQ +LEKF+ VS+GKYTIGLGQ +MGFCSD EDI SI LT
Sbjct: 11 VTDVGIGAIELYFPQNFVDQNDLEKFNNVSSGKYTIGLGQQQMGFCSDNEDIVSISLTVT 70
Query: 323 HRLIDKQKINLHDIGRLEVGTETIIDKSKSVKTFLMTLFAKEGATDIEGIDTTNACYGGT 502
+LI+ KI+ IG L VGTET+IDKSKSVKT LM LF G +DIEG+D NAC+GG
Sbjct: 71 RKLIETYKISTDSIGCLVVGTETMIDKSKSVKTALMDLF--PGNSDIEGVDIKNACFGGA 128
Query: 503 AALFNAINWVE-SSSWDGRKAIVVAGDIAVYGKGPARPTGGAGAVAMLIGPDAPLVFDCG 679
AL +AI+WV + D + AIVV DIA+Y +GPAR TGGAGA+A LI PDA + D
Sbjct: 129 QALLHAIDWVTVNHPLDKKNAIVVVADIAIYEEGPARCTGGAGAIAFLICPDASIPIDRQ 188
Query: 680 VRASYMTHAYDFY 718
A +M + +DF+
Sbjct: 189 FSACHMKNTWDFF 201
>UniRef50_UPI00005A343B Cluster: PREDICTED: similar to
Hydroxymethylglutaryl-CoA synthase, mitochondrial
precursor (HMG-CoA synthase) (3-hydroxy-3-methylglutaryl
coenzyme A synthase); n=1; Canis lupus familiaris|Rep:
PREDICTED: similar to Hydroxymethylglutaryl-CoA
synthase, mitochondrial precursor (HMG-CoA synthase)
(3-hydroxy-3-methylglutaryl coenzyme A synthase) - Canis
familiaris
Length = 417
Score = 214 bits (523), Expect = 2e-54
Identities = 104/188 (55%), Positives = 134/188 (71%), Gaps = 4/188 (2%)
Frame = +2
Query: 122 TVNMGGKVENVGILAMELYFPSQYVDQTELEKFDEVSTGKYTIGLGQSKMGFCSDREDIN 301
+V++G + GILA+E+YFP+ Y+DQT+LE ++ V G Y +G GQ+ MGFCS +ED+N
Sbjct: 14 SVSLGYLAKGYGILALEVYFPTHYMDQTDLENYNNVEAGSYAVGFGQTHMGFCSVQEDLN 73
Query: 302 SICLTALHRLIDKQKINLHDIGRLEVGTETIIDKSKSVKTFLMTLFAKEGATDIEGIDTT 481
S+CLT + +L++ + + +G LEVGTE +IDKSK+VKT LM LF G TDIEGI TT
Sbjct: 74 SLCLTVVQQLMECMQFPWNSVGWLEVGTEMVIDKSKAVKTVLMELFQDSGNTDIEGIGTT 133
Query: 482 NACYGGTAALFNAINWVESSSWDGRKAIVVA---GDIAVYGKGP-ARPTGGAGAVAMLIG 649
NACYGGTA+LFNA NWVESSSWDG A+ A I V G A PTGGA AV +L+G
Sbjct: 134 NACYGGTASLFNAANWVESSSWDGGYAVWSAETLQSIPVIVTGDNAHPTGGARAVTVLVG 193
Query: 650 PDAPLVFD 673
P APL +
Sbjct: 194 PMAPLTLE 201
>UniRef50_A2FZ93 Cluster: Hydroxymethylglutaryl-CoA synthase family
protein; n=2; Trichomonas vaginalis G3|Rep:
Hydroxymethylglutaryl-CoA synthase family protein -
Trichomonas vaginalis G3
Length = 433
Score = 209 bits (510), Expect = 6e-53
Identities = 101/200 (50%), Positives = 139/200 (69%), Gaps = 9/200 (4%)
Frame = +2
Query: 146 ENVGILAMELYFPSQYVDQTELEKFD------EVST---GKYTIGLGQSKMGFCSDREDI 298
+N+GI A+++ P YV Q +LE+ + E T GK+T GLGQ+ + FC+D ED
Sbjct: 5 QNIGIKAIQVNIPRSYVTQDDLEETEISILGEESRTKIKGKFTKGLGQTALSFCTDHEDT 64
Query: 299 NSICLTALHRLIDKQKINLHDIGRLEVGTETIIDKSKSVKTFLMTLFAKEGATDIEGIDT 478
SI ++A+ +L+D D GRLE+G+ET ID+SKS+K+F+M LF + + I G+D
Sbjct: 65 ASIAMSAVQKLMDTYGYKPTDFGRLEIGSETAIDRSKSIKSFVMQLFEENHS--IMGVDN 122
Query: 479 TNACYGGTAALFNAINWVESSSWDGRKAIVVAGDIAVYGKGPARPTGGAGAVAMLIGPDA 658
TNACYGGTAA N++ W+ESS WDGR A+VV DIAVY ARPTGG GAVAM++GPDA
Sbjct: 123 TNACYGGTAAFLNSLAWIESSQWDGRLALVVCADIAVYDDRAARPTGGCGAVAMVLGPDA 182
Query: 659 PLVFDCGVRASYMTHAYDFY 718
P+VF+ G +Y TH++DF+
Sbjct: 183 PIVFEKGSLTNYFTHSFDFW 202
>UniRef50_Q8SR61 Cluster: 3-HYDROXY-3-METHYLGLUTARYL-CoA SYNTHASE 2;
n=1; Encephalitozoon cuniculi|Rep:
3-HYDROXY-3-METHYLGLUTARYL-CoA SYNTHASE 2 -
Encephalitozoon cuniculi
Length = 382
Score = 161 bits (391), Expect = 2e-38
Identities = 87/187 (46%), Positives = 114/187 (60%)
Frame = +2
Query: 155 GILAMELYFPSQYVDQTELEKFDEVSTGKYTIGLGQSKMGFCSDREDINSICLTALHRLI 334
GI+ +E PS Y+ Q E+ + K IGLG +MG S RED S+ L A+ RL+
Sbjct: 8 GIIGVEYQLPSLYISQEEVANNIDFEVDKIKIGLGLEQMGVPSRREDAISLALNAVSRLM 67
Query: 335 DKQKINLHDIGRLEVGTETIIDKSKSVKTFLMTLFAKEGATDIEGIDTTNACYGGTAALF 514
+ ++ IGRLEVGTE+ D SKS+K++L LF G T I G D +ACY GT AL
Sbjct: 68 KRYNVDPMAIGRLEVGTESNPDGSKSIKSYLTDLFP--GNTSICGCDNVHACYSGTNALL 125
Query: 515 NAINWVESSSWDGRKAIVVAGDIAVYGKGPARPTGGAGAVAMLIGPDAPLVFDCGVRASY 694
+AI W+ESS WDGR AIVVA D+A+Y +PTGGAGAVA+L+GP+ Y
Sbjct: 126 SAIAWMESSFWDGRLAIVVASDVAMYKDKSCQPTGGAGAVAILLGPNCIYRVVPSSVIHY 185
Query: 695 MTHAYDF 715
T+ +DF
Sbjct: 186 FTNQFDF 192
>UniRef50_Q1D4I1 Cluster: Hydroxymethylglutaryl-CoA synthase; n=2;
Cystobacterineae|Rep: Hydroxymethylglutaryl-CoA synthase
- Myxococcus xanthus (strain DK 1622)
Length = 418
Score = 128 bits (310), Expect = 1e-28
Identities = 81/194 (41%), Positives = 106/194 (54%), Gaps = 3/194 (1%)
Frame = +2
Query: 146 ENVGILAMELYFPSQYVDQTELEKFDEVSTGKYTIGLGQSKMGFCSDREDINSICLTALH 325
+ VGI A+ + PS+YVD +L + V KYT GLG +M ED ++ TA
Sbjct: 3 KRVGIEALAVAVPSRYVDIEDLARARGVDPAKYTAGLGAREMAVTDPGEDTVALAATAAA 62
Query: 326 RLIDKQKINLHDIGRLEVGTETIIDKSKSVKTFLMTLFAKEGATDIEGIDTTNACYGGTA 505
RLI +Q ++ IG L VGTET ID SK V + + L K T + DT +ACYGGTA
Sbjct: 63 RLIRQQDVDPSRIGMLVVGTETGIDHSKPVASHVQGLL-KLPRT-MRTYDTQHACYGGTA 120
Query: 506 ALFNAINWVESSSWDGRKAIVVAGDIAVYGKGPA-RPTGGAGAVAMLIG--PDAPLVFDC 676
L A+ W+ S + G+ A+VV DIA YG A PT G GAVA+L+ PD L D
Sbjct: 121 GLMAAVEWIASGAGAGKVAVVVCSDIARYGLNTAGEPTQGGGAVALLVSEQPDL-LAMDV 179
Query: 677 GVRASYMTHAYDFY 718
G+ YDF+
Sbjct: 180 GLNGVCSMDVYDFW 193
>UniRef50_Q7QQE4 Cluster: GLP_91_15470_16939; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_91_15470_16939 - Giardia lamblia
ATCC 50803
Length = 489
Score = 123 bits (296), Expect = 5e-27
Identities = 79/199 (39%), Positives = 106/199 (53%), Gaps = 10/199 (5%)
Frame = +2
Query: 152 VGILAMELYFPSQYVDQTELEKFDEVSTGKYTIGLGQSKMGFCSDREDINSICLTALHRL 331
V I A+ +Y P V Q E+ ++ K T GLGQ +M D ED S+ L +L L
Sbjct: 18 VRIAAIAVYIPPIVVSQEEVSSLCKIPLEKITKGLGQHQMAVTVDSEDSVSLALNSLQLL 77
Query: 332 IDKQK----INLHDIGRLEVGTETIIDKSKSVKTFLMTLFAKEGATDIEGIDTTNACYGG 499
ID + ++ IGRLEVGTE+ +DK+KS+K+ L + GA G D NAC GG
Sbjct: 78 IDDKATQDILSKVTIGRLEVGTESSVDKAKSIKSVLADML---GAVRTTGADIINACLGG 134
Query: 500 TAALFNAINWVESSSWDGR-----KAIVVAGDIAVYGKGPARPTGGAGAVAMLIGPDAPL 664
AL NA W+ ++ +D AIVV DI++Y + PTGGAGAVA+L+ D P
Sbjct: 135 VLALENAALWLSAAKYDDETNKYPAAIVVTTDISIYNDIASIPTGGAGAVALLLVKDYPS 194
Query: 665 VFDCGVR-ASYMTHAYDFY 718
C SY + DFY
Sbjct: 195 GIVCDASFNSYWENTTDFY 213
>UniRef50_A0RW92 Cluster: 3-hydroxy-3-methylglutaryl CoA synthase;
n=2; Thermoprotei|Rep: 3-hydroxy-3-methylglutaryl CoA
synthase - Cenarchaeum symbiosum
Length = 464
Score = 109 bits (263), Expect = 5e-23
Identities = 66/195 (33%), Positives = 105/195 (53%), Gaps = 7/195 (3%)
Frame = +2
Query: 155 GILAMELYFPSQYVDQTELEKFDEVSTGKYTIGLGQSKMGFCSDREDINSICLTALHRLI 334
GI + +Y P Y+D + V K GLG ++M +D + A R++
Sbjct: 4 GIDDISVYIPKLYLDAGDYALMRGVDATKLRDGLGVNQMAMVDSNQDPACLAANACLRIM 63
Query: 335 DKQKINLHDIGRLEVGTETIIDKSKSVKTFLMTLFAK---EGATD-IEGIDTTNACYGGT 502
K++ DIGRL V TE+ D+SK++ ++++ + + +G+ + G++T AC G+
Sbjct: 64 QSNKLSPDDIGRLYVSTESSFDESKAMNSYVIGMLEQVYGQGSFEHCGGVETKFACVSGS 123
Query: 503 AALFNAINWVESSSWDGRKAIVVAGDIAVYGKGPA-RPTGGAGAVAMLIGPDAP--LVFD 673
AL++ NW+ + +G A+VV DIA Y KG + T GAGA+AML+ D P L FD
Sbjct: 124 YALYDNANWIRAGEAEGMNALVVVSDIAKYDKGSSGEMTQGAGAIAMLLN-DEPRLLAFD 182
Query: 674 CGVRASYMTHAYDFY 718
V A+ + YDFY
Sbjct: 183 PKVTATSIKDEYDFY 197
>UniRef50_Q5V1G0 Cluster: Hydroxymethylglutaryl-CoA synthase; n=5;
Halobacteriaceae|Rep: Hydroxymethylglutaryl-CoA synthase
- Haloarcula marismortui (Halobacterium marismortui)
Length = 445
Score = 101 bits (241), Expect = 2e-20
Identities = 65/177 (36%), Positives = 91/177 (51%), Gaps = 5/177 (2%)
Frame = +2
Query: 152 VGILAMELYFPSQYVDQTE-LEKFDEVSTGKYTIGLGQSKMGFCSDREDINSICLTALHR 328
VGI AME++ +D E GKYT GLG F EDI ++ A HR
Sbjct: 4 VGIDAMEIWTGKLKLDLAETFAPAQGDDPGKYTKGLGLRASSFPDVYEDIVTMGANAAHR 63
Query: 329 LIDKQKINLHDIGRLEVGTETIIDKSKSVKTFLMTLFAK---EGATDIEGIDTTNACYGG 499
L++++ + DIGR++V TE+ D SK V T++ + E + AC G
Sbjct: 64 LMERKGLTPEDIGRIDVATESAFDNSKPVSTYIAGCLEQVYDENFHHANKGERKFACISG 123
Query: 500 TAALFNAINWVESSSWDGRKAIVVAGDIAVYGK-GPARPTGGAGAVAMLIGPDAPLV 667
T +L +A NW+ + GR A+V+A D A+Y + P T GAGAVAML+ D LV
Sbjct: 124 TQSLDDAYNWIRAGRNRGRAALVIATDTALYARDDPGEATQGAGAVAMLVDEDPNLV 180
>UniRef50_A0NJ77 Cluster: 3-hydroxy-3-methylglutaryl CoA synthase;
n=3; Leuconostocaceae|Rep: 3-hydroxy-3-methylglutaryl
CoA synthase - Oenococcus oeni ATCC BAA-1163
Length = 389
Score = 91.1 bits (216), Expect = 3e-17
Identities = 58/167 (34%), Positives = 88/167 (52%), Gaps = 2/167 (1%)
Frame = +2
Query: 152 VGILAMELYFPSQYVDQTELEKFDEVSTGKYTIGLGQSKMGFCSDREDINSICLTALHRL 331
+GI + + P+ Y+D TEL + V KY +G+GQ K +D S+ A L
Sbjct: 3 IGIDQISFFTPNLYLDLTELAEKRGVDPNKYLVGIGQEKQSIVPPTQDSVSMAANAASIL 62
Query: 332 IDKQKIN-LHDIGRLEVGTETIIDKSKSVKTFLMTLFAKEGATDIEGIDTTNACYGGTAA 508
++++ L+ I + +E+ ID SKS +L L + ++ I+ ACYGGT A
Sbjct: 63 LEQKSTEFLNSIDEILFASESGIDNSKSGAVYLQKLLNLK--KNMRAIEIKQACYGGTFA 120
Query: 509 LFNAINWVESSSWDGRKAIVVAGDIAVYG-KGPARPTGGAGAVAMLI 646
L A ++V+ ++ +VVA DIA YG K T GAGAVAML+
Sbjct: 121 LMTAFDYVKLH--PNKRILVVASDIARYGLKSAGEVTQGAGAVAMLV 165
>UniRef50_A5FM54 Cluster: Hydroxymethylglutaryl-CoA synthase; n=2;
Flavobacteriales|Rep: Hydroxymethylglutaryl-CoA synthase
- Flavobacterium johnsoniae UW101
Length = 453
Score = 86.6 bits (205), Expect = 5e-16
Identities = 58/161 (36%), Positives = 86/161 (53%), Gaps = 5/161 (3%)
Frame = +2
Query: 251 GLGQSKMGFCSDREDINSICLTALHRLIDKQKINLHDIGRLEVGTETIIDKSKSVKTFLM 430
GLG KM F +D AL +LI KI+L +I R+ VGTE+ ID SK + ++L+
Sbjct: 36 GLGLLKMTFPDVHQDAVVFGANALTKLIIDNKIDLKEISRIYVGTESSIDSSKPIASYLI 95
Query: 431 TL----FAKEGATDIEGIDTTNACYGGTAALFNAINWVESSSWDGRKAIVVAGDIAVYG- 595
+L F ++ + + +D T AC GG A+ N +++V+ + +KAIVV D A Y
Sbjct: 96 SLMEQKFGEDSLAECDVVDFTFACIGGVDAMQNCLDFVKLN--PAKKAIVVTSDFAKYDL 153
Query: 596 KGPARPTGGAGAVAMLIGPDAPLVFDCGVRASYMTHAYDFY 718
T GAGAVAMLI D ++ A+ +DF+
Sbjct: 154 NSGGEYTQGAGAVAMLITADPKIIAFDDNWATSTKGVFDFF 194
>UniRef50_Q88VI4 Cluster: Hydroxymethylglutaryl-CoA synthase; n=44;
Bacilli|Rep: Hydroxymethylglutaryl-CoA synthase -
Lactobacillus plantarum
Length = 389
Score = 85.4 bits (202), Expect = 1e-15
Identities = 64/191 (33%), Positives = 90/191 (47%), Gaps = 2/191 (1%)
Frame = +2
Query: 152 VGILAMELYFPSQYVDQTELEKFDEVSTGKYTIGLGQSKMGFCSDREDINSICLTALHRL 331
VGI + YVD EL + KY IG+GQSKM +D ++ A +
Sbjct: 3 VGIDKLHFATSHLYVDMAELATARQAEPDKYLIGIGQSKMAVIPPSQDAVTLAANAAAPM 62
Query: 332 IDKQKINLHDIGRLEVGTETIIDKSKSVKTFLMTLFAKEGATDIEGIDTTNACYGGTAAL 511
+ I D+ L VGTE+ ID SK+ ++ L + + I+ ACY TA +
Sbjct: 63 LTATDIAAIDL--LVVGTESGIDNSKASAIYVAKLLGL--SQRVRTIEMKEACYAATAGV 118
Query: 512 FNAINWVESSSWDGRKAIVVAGDIAVYG-KGPARPTGGAGAVAMLIGPDAPLVFDCGVRA 688
A + V +KA+V+ D+A YG P PT G GAVAMLI D P V G +
Sbjct: 119 QLAQDHVRVH--PDKKALVIGSDVARYGLNTPGEPTQGGGAVAMLISAD-PKVLALGTES 175
Query: 689 SYMTH-AYDFY 718
S ++ DF+
Sbjct: 176 SLLSEDVMDFW 186
>UniRef50_Q9FD82 Cluster: HMG-CoA synthase; n=16;
Staphylococcus|Rep: HMG-CoA synthase - Staphylococcus
haemolyticus
Length = 388
Score = 84.2 bits (199), Expect = 3e-15
Identities = 58/191 (30%), Positives = 91/191 (47%), Gaps = 1/191 (0%)
Frame = +2
Query: 149 NVGILAMELYFPSQYVDQTELEKFDEVSTGKYTIGLGQSKMGFCSDREDINSICLTALHR 328
++GI + Y P YVD +L + +V K+ IG+GQ++M +DI S+ A
Sbjct: 2 SIGIDKINFYVPKYYVDMAKLAEARQVDPNKFLIGIGQTQMAVSPVSQDIVSMGANAAKD 61
Query: 329 LIDKQKINLHDIGRLEVGTETIIDKSKSVKTFLMTLFAKEGATDIEGIDTTNACYGGTAA 508
+I + IG + V TE+ ID +K+ + L + + ACY T A
Sbjct: 62 IITDD--DKKHIGMVIVATESAIDNAKAAAVQIHNLLGVQPFA--RCFEMKEACYAATPA 117
Query: 509 LFNAINWVESSSWDGRKAIVVAGDIAVYG-KGPARPTGGAGAVAMLIGPDAPLVFDCGVR 685
+ A +++E K +V+A D A YG + PT GAGAVAMLI + ++
Sbjct: 118 IQLAKDYIEKR--PNEKVLVIASDTARYGIQSGGEPTQGAGAVAMLISNNPSILELNDDA 175
Query: 686 ASYMTHAYDFY 718
+Y YDF+
Sbjct: 176 VAYTEDVYDFW 186
>UniRef50_A5EUV4 Cluster: Hydroxymethylglutaryl-CoA synthase; n=1;
Dichelobacter nodosus VCS1703A|Rep:
Hydroxymethylglutaryl-CoA synthase - Dichelobacter
nodosus (strain VCS1703A)
Length = 384
Score = 79.8 bits (188), Expect = 6e-14
Identities = 60/190 (31%), Positives = 88/190 (46%), Gaps = 1/190 (0%)
Frame = +2
Query: 152 VGILAMELYFPSQYVDQTELEKFDEVSTGKYTIGLGQSKMGFCSDREDINSICLTALHRL 331
VGI + Y P Y++ + L + D V KY GLGQ + EDI ++ A L
Sbjct: 4 VGIDKIGFYIPKYYMELSTLAQRDGVEAKKYHEGLGQMRFAVAPHDEDIVTLASNAAFAL 63
Query: 332 IDKQKINLHDIGRLEVGTETIIDKSKSVKTFLMTLFAKEGATDIEGIDTTNACYGGTAAL 511
ID+ + I + V TET ID+SKS ++ L + ++ ACY TA L
Sbjct: 64 IDED--DRQAIDSVIVATETGIDQSKSAAVYVHRLL--NLSPRCRAVELKQACYSTTAGL 119
Query: 512 FNAINWVESSSWDGRKAIVVAGDIAVYG-KGPARPTGGAGAVAMLIGPDAPLVFDCGVRA 688
A ++V ++ RK +++A DIA Y A T G AVAM+I + G+
Sbjct: 120 QFACSYV--AAHPNRKVLLIASDIARYDLHSAAEVTQGCAAVAMVIAAHPRIAVWHGLSG 177
Query: 689 SYMTHAYDFY 718
Y DF+
Sbjct: 178 IYTEEVMDFW 187
>UniRef50_Q04AW0 Cluster: 3-hydroxy-3-methylglutaryl CoA synthase;
n=4; Lactobacillus delbrueckii|Rep:
3-hydroxy-3-methylglutaryl CoA synthase - Lactobacillus
delbrueckii subsp. bulgaricus (strain ATCC BAA-365)
Length = 387
Score = 77.4 bits (182), Expect = 3e-13
Identities = 55/191 (28%), Positives = 93/191 (48%), Gaps = 1/191 (0%)
Frame = +2
Query: 149 NVGILAMELYFPSQYVDQTELEKFDEVSTGKYTIGLGQSKMGFCSDREDINSICLTALHR 328
++GI + Y P+++VD +L K+ IG+GQ +M +D S+ + A
Sbjct: 2 DIGIDQIGFYTPNKFVDMVDLANARNQDPNKFLIGIGQDRMAVADKTQDAVSMGINATAE 61
Query: 329 LIDKQKINLHDIGRLEVGTETIIDKSKSVKTFLMTLFAKEGATDIEGIDTTNACYGGTAA 508
+D +++L +G L TE+ ID+SKS F+ A I + AC+ TA+
Sbjct: 62 YLD--QVDLEQLGLLIFATESGIDQSKSASLFVKE--ALNLPARIRTFEIKEACFALTAS 117
Query: 509 LFNAINWVESSSWDGRKAIVVAGDIAVYGKGPA-RPTGGAGAVAMLIGPDAPLVFDCGVR 685
L A ++V + A+++ DIA YG A T GAGA++MLI + ++
Sbjct: 118 LQVARDYVRAH--PHHSAMIIGSDIARYGLATAGEVTQGAGAISMLIKENPAIIALEDGH 175
Query: 686 ASYMTHAYDFY 718
S+ + DF+
Sbjct: 176 TSHSENINDFW 186
>UniRef50_A7QFV6 Cluster: Chromosome undetermined scaffold_89, whole
genome shotgun sequence; n=2; Magnoliophyta|Rep:
Chromosome undetermined scaffold_89, whole genome
shotgun sequence - Vitis vinifera (Grape)
Length = 117
Score = 73.7 bits (173), Expect = 4e-12
Identities = 45/101 (44%), Positives = 60/101 (59%), Gaps = 3/101 (2%)
Frame = +2
Query: 146 ENVGILAMELYFPSQYVDQTELEKFDEVSTGKYTIGLGQSKM---GFCSDREDINSICLT 316
+NVGILAM++YFP V Q TG L S + FCS+ ED+ S+ T
Sbjct: 3 KNVGILAMDIYFPPSCVQQV---------TGLSLCFLFLSLIFLPAFCSEVEDVISMSST 53
Query: 317 ALHRLIDKQKINLHDIGRLEVGTETIIDKSKSVKTFLMTLF 439
+ L++K I+ I +LEVG ET+IDKSKS+KTFLM +F
Sbjct: 54 VVTSLLEKYGIDTKQISQLEVGNETVIDKSKSIKTFLMQIF 94
>UniRef50_Q8L1I3 Cluster: HMG-CoA synthase; n=1; Paracoccus
zeaxanthinifaciens|Rep: HMG-CoA synthase - Paracoccus
zeaxanthinifaciens
Length = 388
Score = 73.3 bits (172), Expect = 5e-12
Identities = 59/195 (30%), Positives = 90/195 (46%), Gaps = 2/195 (1%)
Frame = +2
Query: 140 KVENVGILAMELYFPSQYVDQTELEKFDEVSTGKYTIGLGQSKMGFCSDREDINSICLTA 319
K+ GI A+ Y P YV L + K++ G+GQ K+ EDI ++ A
Sbjct: 5 KMTVTGIEAISFYTPQNYVGLDILAAHHGIDPEKFSKGIGQEKIALPGHDEDIVTMAAEA 64
Query: 320 LHRLIDKQKINLHDIGRLEVGTETIIDKSKSVKTFLMTLFAKEGATDIEGIDTTNACYGG 499
+I ++ I + TE+ ID+SK+ +L L + + + ++ ACY
Sbjct: 65 ALPII--ERAGTQGIDTVLFATESGIDQSKAAAIYLRRLL--DLSPNCRCVELKQACYSA 120
Query: 500 TAALFNAINWVESSSWDGRKAIVVAGDIAVYGK-GPARPTGGAGAVAMLIGPDAPLVFDC 676
TAAL A V RK +V+A D+A Y + T GAGAVA+L+ D P V +
Sbjct: 121 TAALQMACAHVARK--PDRKVLVIASDVARYDRESSGEATQGAGAVAILVSAD-PKVAEI 177
Query: 677 GVRASYMTH-AYDFY 718
G + T DF+
Sbjct: 178 GTVSGLFTEDIMDFW 192
>UniRef50_A4FIG4 Cluster: Hydroxymethylglutaryl-CoA synthase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
Hydroxymethylglutaryl-CoA synthase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 407
Score = 70.9 bits (166), Expect = 3e-11
Identities = 58/191 (30%), Positives = 90/191 (47%), Gaps = 2/191 (1%)
Frame = +2
Query: 152 VGILAMELYFPSQYVDQTELEKFDEVSTGKYTIGLGQSKMGFCSDREDINSICLTALHRL 331
VGI A+ Y S Y++ +L + G+ LG + + ED+ ++ TA L
Sbjct: 5 VGIEAVGAYCGSAYLETEDLFAARGLDAGRIG-NLGLRRKSVAAPGEDVVAMAATAARPL 63
Query: 332 IDKQKINLHDIGRLEVGTETIIDKSKSVKTFLMTLFAKEGATDIEGIDTTNACYGGTAAL 511
+D + I L V TE+ +D SK+ T + L + ++ AC+GG AAL
Sbjct: 64 VDAVD-DKASIRTLVVATESPLDLSKAASTHVHQLLGLPRQCRL--LEVKQACHGGAAAL 120
Query: 512 FNAINWVESSSWDGRKAIVVAGDIAVYGKGP-ARPTGGAGAVAMLIGPDAPLV-FDCGVR 685
A + V + G +A+V+A D V +G P GAGAVA+L+GP +V + G
Sbjct: 121 GLAASVVATEP--GSRALVIASDTPVPTRGSYMEPAQGAGAVAVLVGPQPRVVELELGTT 178
Query: 686 ASYMTHAYDFY 718
Y DF+
Sbjct: 179 GCYGYETPDFF 189
>UniRef50_Q9FD56 Cluster: HMG-CoA synthase; n=46;
Streptococcaceae|Rep: HMG-CoA synthase - Streptococcus
pneumoniae
Length = 398
Score = 67.7 bits (158), Expect = 3e-10
Identities = 53/156 (33%), Positives = 81/156 (51%), Gaps = 2/156 (1%)
Frame = +2
Query: 185 SQYVDQTE-LEKFDEVSTGKYTIGLGQSKMGFCSDREDINSICLTALHRLIDKQKINLHD 361
SQYV + + L + + K + GL ++ EDI ++ +A ++ +Q+ +
Sbjct: 21 SQYVLKLQDLAEARGIDPEKLSKGLLLKELSIAPLTEDIVTLAASASDSILTEQE--RQE 78
Query: 362 IGRLEVGTETIIDKSKSVKTFLMTLFAKEGATDIEGIDTTNACYGGTAALFNAINWVESS 541
+ + V TE+ ID+SK+ F+ L + + ACYG TAAL A VE+S
Sbjct: 79 VDMVIVATESGIDQSKAAAVFVHGLLGIQPFA--RSFEIKEACYGATAALHYAKLHVENS 136
Query: 542 SWDGRKAIVVAGDIAVYG-KGPARPTGGAGAVAMLI 646
K +V+A DIA YG + P PT GAG+VAMLI
Sbjct: 137 PES--KVLVIASDIAKYGIETPGEPTQGAGSVAMLI 170
>UniRef50_P40830 Cluster: Putative polyketide biosynthesis protein
pksG; n=31; Bacteria|Rep: Putative polyketide
biosynthesis protein pksG - Bacillus subtilis
Length = 420
Score = 62.1 bits (144), Expect = 1e-08
Identities = 59/196 (30%), Positives = 92/196 (46%), Gaps = 14/196 (7%)
Frame = +2
Query: 149 NVGILAMELYFPSQYVDQTELEKFDEVSTGKYTIGLGQSKMGFCSDREDINSICLTALHR 328
+ GI AM ++ + Y+D EL K+ + T ++ L + K ED + + A
Sbjct: 3 SAGIEAMNVFGGTAYLDVMELAKYRHLDTARFENLLMKEK-AVALPYEDPVTFGVNAAKP 61
Query: 329 LIDKQKINLHD-IGRLEVGTETIIDKSKSVKTFLMTLFAKEGATDIEGIDTTNACYGGTA 505
+ID D I L +E+ ID KS+ T++ + + ACY GTA
Sbjct: 62 IIDALSEAEKDRIELLITCSESGIDFGKSLSTYIHEYLGLNRNCRL--FEVKQACYSGTA 119
Query: 506 ALFNAINWVESSSWDGRKAIVVAGDIA--VYGKGP---------ARPTGGAGAVAMLIGP 652
A+N++ S + G KA+V+A DI+ + +G A P+ GAGAVA+L+G
Sbjct: 120 GFQMAVNFILSQTSPGAKALVIASDISRFLIAEGGDALSEDWSYAEPSAGAGAVAVLVG- 178
Query: 653 DAPLVF--DCGVRASY 694
+ P VF D G Y
Sbjct: 179 ENPEVFQIDPGANGYY 194
>UniRef50_Q767G7 Cluster: HMG-CoA synthase; n=9; Bacteria|Rep:
HMG-CoA synthase - Actinoplanes sp. A40644
Length = 391
Score = 61.3 bits (142), Expect = 2e-08
Identities = 47/162 (29%), Positives = 77/162 (47%), Gaps = 2/162 (1%)
Frame = +2
Query: 188 QYVDQTE-LEKFDEVSTGKYTIGLGQSKMGFCSDREDINSICLTALHRLIDKQKINLHDI 364
QYV E L + KY G+GQ M + EDI ++ A ++ + + I
Sbjct: 18 QYVLTHETLAAENGADVAKYHKGIGQRSMSVPAVDEDIVTMAAAAAAPVVARHGAD--QI 75
Query: 365 GRLEVGTETIIDKSKSVKTFLMTLFAKEGATDIEGIDTTNACYGGTAALFNAINWVESSS 544
+ TE+ ID++K+ ++ +L + ++ ACY GTAAL A+ V
Sbjct: 76 RTVLFATESSIDQAKAAGIYVHSLLGLPAGARV--VELKQACYSGTAALQFALGLVHRDR 133
Query: 545 WDGRKAIVVAGDIAVYGKG-PARPTGGAGAVAMLIGPDAPLV 667
+ +V+A D++ Y +G P T GA AVAML+ + L+
Sbjct: 134 --SEQVLVIASDVSKYERGTPGEATQGAAAVAMLVSAEPALM 173
>UniRef50_A6G7N7 Cluster: Hydroxymethylglutaryl-coenzyme A synthase;
n=1; Plesiocystis pacifica SIR-1|Rep:
Hydroxymethylglutaryl-coenzyme A synthase - Plesiocystis
pacifica SIR-1
Length = 420
Score = 59.7 bits (138), Expect = 7e-08
Identities = 38/107 (35%), Positives = 56/107 (52%), Gaps = 1/107 (0%)
Frame = +2
Query: 344 KINLHDIGRLEVGTETIIDKSKSVKTFLMTLFAKEGATDIEGIDTTNACYGGTAALFNAI 523
+I+ + + VGTE+ +D K + +++ L + + +T +ACYGGT L A
Sbjct: 78 EIDPKQVEMIVVGTESSVDFGKPISSWVQRLSG--ASANCRNFETKHACYGGTGGLMAAA 135
Query: 524 NWVESSSWDGRKAIVVAGDIAVYGKG-PARPTGGAGAVAMLIGPDAP 661
+WV S G+KA+VV D + G P GAGA AMLI D P
Sbjct: 136 HWVASGFNRGKKALVVCADQSRMHLGKPWEFVLGAGATAMLIS-DQP 181
>UniRef50_A6G789 Cluster: Hydroxymethylglutaryl-CoA synthase; n=1;
Plesiocystis pacifica SIR-1|Rep:
Hydroxymethylglutaryl-CoA synthase - Plesiocystis
pacifica SIR-1
Length = 510
Score = 58.4 bits (135), Expect = 2e-07
Identities = 57/199 (28%), Positives = 90/199 (45%), Gaps = 12/199 (6%)
Frame = +2
Query: 155 GILAMELYFPSQYVDQTELEKFDEVSTGKYTIGLGQSKMGFCSDREDINSICLTALHRLI 334
GI A+ +Y P VD ++ K +G+S C+ E++ ++ A +LI
Sbjct: 15 GISAISIYLPRNRVDLERWCEWTGAPWAKVAAVVGRS-FRVCAPDENVYTMAANAALQLI 73
Query: 335 DKQKINLHDIGRLEVGTETIIDKSKS---VKTFLMTLFAKEG----ATDIEGIDTTNACY 493
+ I+ +G +GTE+ D + V+ + G A D E + +AC
Sbjct: 74 EANGIDPRRVGYFALGTESSTDNAAGAVIVRGMVDEALRVRGLPSLARDCEVPEFKHACL 133
Query: 494 GGTAALFNAINWVESSSWDGRKAIVVAGDIAVYGKGPA-RPTGGAGAVAMLIGPDAPLV- 667
GG A+ +A ++ + R AIVV+ DIA Y +G T GAGAVA + + L+
Sbjct: 134 GGVYAMKSAARYLACEGRE-RVAIVVSSDIAAYRRGSTGEQTQGAGAVAFAMEAEPKLLA 192
Query: 668 FD---CGVRASYMTHAYDF 715
D G +SY YDF
Sbjct: 193 LDLDRAGSASSY--RGYDF 209
>UniRef50_Q4QAB9 Cluster: Putative uncharacterized protein; n=5;
Trypanosomatidae|Rep: Putative uncharacterized protein -
Leishmania major
Length = 501
Score = 58.4 bits (135), Expect = 2e-07
Identities = 58/187 (31%), Positives = 85/187 (45%), Gaps = 8/187 (4%)
Frame = +2
Query: 155 GILAMELYFPSQYVDQTELEKFDEVSTGKYTIGLGQSKMGFCSDREDINSICLTALHRLI 334
G+ M +Y P VD + K+ S K + +GQS S E+ ++ A+ RLI
Sbjct: 11 GVSGMAVYAPHCRVDLEQWCKWTGNSWDKVSSVVGQS-FRITSHNENAYTMAANAVLRLI 69
Query: 335 DKQKINLHDIGRLEVGTETIIDKSKS-------VKTFLMTLFAKEGATDIEGIDTTNACY 493
I+ IG L +GTE+ D S V L + + E + +AC
Sbjct: 70 VNNNIDPTKIGFLGLGTESSSDNSAGAIIVKGMVDKGLRAMNMPAMSRHCEVPEFKHACL 129
Query: 494 GGTAALFNAINWVESSSWDGRKAIVVAGDIAVYGKG-PARPTGGAGAVAMLIGPDAPLVF 670
G A+ +A +V + D R AI VA DIA Y G T GAGA AM++ D P +F
Sbjct: 130 AGVYAMESATRFVNADGKD-RMAIAVASDIAEYALGSTGEQTQGAGATAMVLEHD-PKLF 187
Query: 671 DCGVRAS 691
+ ++ S
Sbjct: 188 EVQLQHS 194
>UniRef50_UPI000038D51C Cluster: COG3425: 3-hydroxy-3-methylglutaryl
CoA synthase; n=1; Nostoc punctiforme PCC 73102|Rep:
COG3425: 3-hydroxy-3-methylglutaryl CoA synthase -
Nostoc punctiforme PCC 73102
Length = 408
Score = 53.2 bits (122), Expect = 6e-06
Identities = 48/178 (26%), Positives = 75/178 (42%), Gaps = 1/178 (0%)
Frame = +2
Query: 143 VENVGILAMELYFPSQYVDQTELEKFDEVSTGKYTIGLGQSKMGFCSDREDINSICLTAL 322
++ VGI + LY D EL + + ED ++ + A
Sbjct: 1 MQRVGIEKINLYAGRFCADALELANLQGKDLDYVSKQVKVKTRSVIPAYEDTVTLSVNAA 60
Query: 323 HRLIDKQKINLHDIGRLEVGTETIIDKSKSVKTFLMTLFAKEGATDIEGIDTTNACYGGT 502
RL+ + + DI L V TE+ +D K V T++ + +ACYG T
Sbjct: 61 KRLLSPE--DARDIELLIVATESAVDFGKPVSTWVHRYCNLP--PHCRSFELKHACYGLT 116
Query: 503 AALFNAINWVESSSWDGRKAIVVAGDIA-VYGKGPARPTGGAGAVAMLIGPDAPLVFD 673
AA+ A W++ G+KA+V+ D + + GG A+AMLI D P VF+
Sbjct: 117 AAVKTAAMWLQGGLTPGKKALVIGCDYSRPHLDDRDNFIGGGAAIAMLISTD-PKVFE 173
>UniRef50_Q1CGN1 Cluster: Hydroxymethylglutaryl-coenzyme A synthase;
n=8; Yersinia|Rep: Hydroxymethylglutaryl-coenzyme A
synthase - Yersinia pestis (biovar Antiqua strain
Nepal516)
Length = 412
Score = 49.6 bits (113), Expect = 8e-05
Identities = 42/176 (23%), Positives = 81/176 (46%), Gaps = 2/176 (1%)
Frame = +2
Query: 143 VENVGILAMELYFPSQYVDQTELEKFDEVSTGKYTIGLGQSKMGFCSDREDINSICLTAL 322
+ ++GI + +Y S + +EL + L K ED ++ + +
Sbjct: 1 MNSIGIEKISIYPSSLALKLSELAQARGGDNKYIQESLMVIKRSLVPQWEDAVTLAVNSA 60
Query: 323 HRLIDKQKINLHDIGRLEVGTETIIDKSKSVKTFLMTLFAKEGATDIEGIDTTNACYGGT 502
+++ Q + DIG + TE+ +D+ K++ T+ + + +AC+ G
Sbjct: 61 KDMLNDQ--DRSDIGLFIIATESGLDQEKAISTWAHRYLGLPATCRV--FELKSACHAGA 116
Query: 503 AALFNAINWVESSSWDGRKAIVVAGDIA--VYGKGPARPTGGAGAVAMLIGPDAPL 664
AAL A +W+ S G+K +++ DI+ + G + GAGA+A+LI D P+
Sbjct: 117 AALKMAESWISSGLNRGKKVLLINVDISNNMICHGKMEYSLGAGAIALLIS-DNPV 171
>UniRef50_Q6MLJ5 Cluster: 3-oxoacyl-(Acyl-carrier-protein) synthase
III; n=1; Bdellovibrio bacteriovorus|Rep:
3-oxoacyl-(Acyl-carrier-protein) synthase III -
Bdellovibrio bacteriovorus
Length = 331
Score = 44.0 bits (99), Expect = 0.004
Identities = 28/107 (26%), Positives = 47/107 (43%)
Frame = +2
Query: 176 YFPSQYVDQTELEKFDEVSTGKYTIGLGQSKMGFCSDREDINSICLTALHRLIDKQKINL 355
Y P + + +LEK E + G + S+ + + +C+ A R ++ + +
Sbjct: 15 YLPEKILSNKDLEKMVETNDQWIVERTGIERRHIASEDQATSDLCVIAAKRALEDANLKV 74
Query: 356 HDIGRLEVGTETIIDKSKSVKTFLMTLFAKEGATDIEGIDTTNACYG 496
DI + VGT T + S F+ AK GA +I +D AC G
Sbjct: 75 EDIDMILVGTVTGDHQMPSTACFVQ---AKLGAKNIMAVDLNAACSG 118
>UniRef50_P51196 Cluster: 3-oxoacyl-[acyl-carrier-protein] synthase
3; n=3; Porphyra|Rep: 3-oxoacyl-[acyl-carrier-protein]
synthase 3 - Porphyra purpurea
Length = 326
Score = 42.7 bits (96), Expect = 0.009
Identities = 38/143 (26%), Positives = 57/143 (39%)
Frame = +2
Query: 152 VGILAMELYFPSQYVDQTELEKFDEVSTGKYTIGLGQSKMGFCSDREDINSICLTALHRL 331
V IL+ P+ V+ + E E S + G K + + A +
Sbjct: 3 VHILSTGSSVPNFSVENQQFEDIIETSDHWISTRTGIKKRHLAPSSTSLTKLAAEAANDA 62
Query: 332 IDKQKINLHDIGRLEVGTETIIDKSKSVKTFLMTLFAKEGATDIEGIDTTNACYGGTAAL 511
+ K IN DI + + T T D S L A+ GAT D T AC G AL
Sbjct: 63 LSKASINAEDIDLIILATSTPDDLFGSASQ----LQAEIGATSSTAFDITAACSGFIIAL 118
Query: 512 FNAINWVESSSWDGRKAIVVAGD 580
A ++++ S++ K +VV D
Sbjct: 119 VTASQFIQAGSYN--KVLVVGAD 139
>UniRef50_Q81JG0 Cluster: 3-oxoacyl-[acyl-carrier-protein] synthase
3 protein 1; n=21; Bacteria|Rep:
3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 1 -
Bacillus anthracis
Length = 310
Score = 39.9 bits (89), Expect = 0.061
Identities = 44/195 (22%), Positives = 77/195 (39%), Gaps = 8/195 (4%)
Frame = +2
Query: 149 NVGILAMELYFPSQYVDQTELEKFDEVSTGKYTIGLGQSKMGFCSDREDINSICLTALHR 328
NVGIL + Y P + V +LEK + S G ++ D D + + + A +
Sbjct: 2 NVGILGIGRYVPEKVVTNHDLEKIMDTSDEWIRTRTGIAERRIADDTIDTSYMAVEASKK 61
Query: 329 LIDKQKINLHDIGRLEVGTETIIDKSKSVKTFLMTLFAKEGATDIEGIDTTNACYGGTAA 508
++ I+ DI + V T T ++ + GA +D + AC G
Sbjct: 62 ALEDAGISGEDIDLILVATVT---PDRAFPAVACVIQEAIGAKHAAAMDLSAACAGFMYG 118
Query: 509 LFNAINWVESSSWDGRKAIVVAGD----IAVYGKGPARPTGGAGAVAMLIGP----DAPL 664
+ A ++++ ++ + +VV D I + G GA A+++G L
Sbjct: 119 MITAQQFIQTGTY--KNVLVVGSDKLSKIVDWNDRNTAVLFGDGAGAIVMGAVSEGKGVL 176
Query: 665 VFDCGVRASYMTHAY 709
F+ G S H Y
Sbjct: 177 SFELGADGSGGKHLY 191
>UniRef50_Q1VIJ1 Cluster: 3-hydroxy-3-methylglutaryl-coenzyme A
synthase; n=1; Psychroflexus torquis ATCC 700755|Rep:
3-hydroxy-3-methylglutaryl-coenzyme A synthase -
Psychroflexus torquis ATCC 700755
Length = 89
Score = 39.5 bits (88), Expect = 0.081
Identities = 24/81 (29%), Positives = 36/81 (44%)
Frame = +2
Query: 125 VNMGGKVENVGILAMELYFPSQYVDQTELEKFDEVSTGKYTIGLGQSKMGFCSDREDINS 304
V G VG+ + ++ P Y+D E + E K GLG S M ED +
Sbjct: 9 VTSEGNSITVGVDDLAIHVPRLYLDMREFAELREADYDKLNKGLGLSAMAIPDVHEDTAT 68
Query: 305 ICLTALHRLIDKQKINLHDIG 367
+ A+ RLID+ ++ IG
Sbjct: 69 MGAMAVMRLIDRNGLDPRGIG 89
>UniRef50_Q97CG9 Cluster: UPF0219 protein TV0132; n=37; cellular
organisms|Rep: UPF0219 protein TV0132 - Thermoplasma
volcanium
Length = 351
Score = 38.7 bits (86), Expect = 0.14
Identities = 37/168 (22%), Positives = 68/168 (40%), Gaps = 1/168 (0%)
Frame = +2
Query: 155 GILAMELYFPSQYVDQTELEKFDEVSTGKYTIGLGQSKMGFCSDREDINSICLTALHRLI 334
GI+ Y P + E+ + + + G+ + ED+ +I + A +
Sbjct: 3 GIVTYGSYIPRYRIKPDEIARVWGENPERIKNGIFILSKSVPAPDEDVATISVEAARNAL 62
Query: 335 DKQKINLHDIGRLEVGTETIIDKSKSVKTFLMTLFAKEGATDIEGIDTTNACYGGTAALF 514
++KIN +IG + VG+E+ K T + + + + D AC GTA +
Sbjct: 63 KRKKINPKEIGAIYVGSESHPYAVKPTATIVGSAIGVD--FSLFAADYEFACKAGTAGMQ 120
Query: 515 NAINWVESSSWDGRKAIVVAGDIAVYGKGPA-RPTGGAGAVAMLIGPD 655
N V++ + + + D + G A + AG A +IG D
Sbjct: 121 NVKAMVDAGMI--KYGLAIGADTSQGAPGDALEYSASAGGSAFIIGKD 166
>UniRef50_A2Z2A6 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. indica (Rice)
Length = 980
Score = 35.9 bits (79), Expect = 1.00
Identities = 20/51 (39%), Positives = 27/51 (52%)
Frame = +2
Query: 515 NAINWVESSSWDGRKAIVVAGDIAVYGKGPARPTGGAGAVAMLIGPDAPLV 667
+ + W E ++ GR + VVAG A PA P+GGAG A AP+V
Sbjct: 6 DGVGW-EGATLTGRCSDVVAGAAAGVAAPPAAPSGGAGEAAAAAAEAAPVV 55
>UniRef50_Q9KET5 Cluster: 3-oxoacyl-[acyl-carrier-protein] synthase
3 protein 2; n=16; Bacillales|Rep:
3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 2 -
Bacillus halodurans
Length = 332
Score = 35.5 bits (78), Expect = 1.3
Identities = 37/146 (25%), Positives = 61/146 (41%)
Frame = +2
Query: 143 VENVGILAMELYFPSQYVDQTELEKFDEVSTGKYTIGLGQSKMGFCSDREDINSICLTAL 322
V I A+ Y P + + +LEK + + G + +D E + I A+
Sbjct: 3 VSKARITAIGSYVPERRLTNDDLEKMVDTNDEWIVKRTGIRERRIAADDEFTSDIGYKAV 62
Query: 323 HRLIDKQKINLHDIGRLEVGTETIIDKSKSVKTFLMTLFAKEGATDIEGIDTTNACYGGT 502
LI + + ++ D+ + V T T K+ S + + AK G + ID AC G T
Sbjct: 63 QDLIARYEKSVDDVDMIIVCTFTPDFKTPSAASLIQ---AKLGIQNTGAIDLNAACAGFT 119
Query: 503 AALFNAINWVESSSWDGRKAIVVAGD 580
L A + SS RK +V+ +
Sbjct: 120 YGLHMANGLI--SSGLHRKILVIGAE 143
>UniRef50_Q13PK8 Cluster: Putative uncharacterized protein; n=2;
Burkholderia xenovorans LB400|Rep: Putative
uncharacterized protein - Burkholderia xenovorans
(strain LB400)
Length = 182
Score = 35.1 bits (77), Expect = 1.7
Identities = 20/49 (40%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
Frame = +2
Query: 503 AALFNAINWVESSSWDGRKAIVVAGDIAV-YGKGPARPTGGAGAVAMLI 646
+A F +N+V S++W G AI+V DIA+ Y P TG +V LI
Sbjct: 116 SAHFLHVNYVISAAWAGAFAILVLADIAMAYAPAPLHSTGVIASVIALI 164
>UniRef50_A4F133 Cluster: Putative uncharacterized protein; n=1;
Roseobacter sp. SK209-2-6|Rep: Putative uncharacterized
protein - Roseobacter sp. SK209-2-6
Length = 295
Score = 35.1 bits (77), Expect = 1.7
Identities = 19/67 (28%), Positives = 35/67 (52%), Gaps = 1/67 (1%)
Frame = +2
Query: 179 FPSQYVDQTELEKFDEVST-GKYTIGLGQSKMGFCSDREDINSICLTALHRLIDKQKINL 355
F ++++ ++ FD V+ KY + + + +G C RED+ + ++HR D K L
Sbjct: 105 FHQRFIETATVKNFDPVNRKSKYAL-MDTACVGQCRTREDLLLLTRVSMHRRQDFPKFEL 163
Query: 356 HDIGRLE 376
+GR E
Sbjct: 164 AGVGRQE 170
>UniRef50_UPI0000D5795B Cluster: PREDICTED: similar to CG12149-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG12149-PA - Tribolium castaneum
Length = 1083
Score = 33.9 bits (74), Expect = 4.0
Identities = 28/104 (26%), Positives = 46/104 (44%), Gaps = 2/104 (1%)
Frame = +2
Query: 116 QYTVNMGGK-VENVGILAMELYFPSQYVDQTELEKFDEVST-GKYTIGLGQSKMGFCSDR 289
Q N+ GK EN+ +L ++ +T LE D V T + + K+
Sbjct: 151 QQVANIAGKQTENI-VLYQDMTARDLIQQRTTLENGDTVWTLSPLVLAALEGKIAVLDGI 209
Query: 290 EDINSICLTALHRLIDKQKINLHDIGRLEVGTETIIDKSKSVKT 421
I+ L+ LHRL+ +++ LHD RL + K+K+ T
Sbjct: 210 HRIHPSTLSCLHRLVQNRELQLHDGKRLISHERYQLLKTKTTPT 253
>UniRef50_Q419Z7 Cluster: Beta-ketoacyl-acyl carrier protein
synthase III; n=1; Exiguobacterium sibiricum 255-15|Rep:
Beta-ketoacyl-acyl carrier protein synthase III -
Exiguobacterium sibiricum 255-15
Length = 314
Score = 33.5 bits (73), Expect = 5.3
Identities = 35/172 (20%), Positives = 65/172 (37%), Gaps = 4/172 (2%)
Frame = +2
Query: 149 NVGILAMELYFPSQYVDQTELEKFDEVSTGKYTIGLGQSKMGFCSDREDINSICLTALHR 328
N+GI+ + P + +L + S G D D+ + A +
Sbjct: 2 NIGIVGLGTSLPEHRMTNDDLAATLDTSDEWIRSRTGIGARRIADDAVDVTDLATEAAQK 61
Query: 329 LIDKQKINLHDIGRLEVGTETIIDKSKSVKTFLMTLFAKEGATDIEGIDTTNACYGGTAA 508
+ + DIG + VGT T ++ + + + GA D + AC G A
Sbjct: 62 ALADANLTADDIGLIVVGTAT----GRAFPSTACIVQERIGALGATAFDISAACSGFIFA 117
Query: 509 LFNAINWVESSSWDGRKAIVVAGD----IAVYGKGPARPTGGAGAVAMLIGP 652
L A + + ++ + A+V+ + I + G GA A+++GP
Sbjct: 118 LQTASSMMTATG--SKHALVIGAEKMSSIVDWSDRSTAILFGDGAGAVVLGP 167
>UniRef50_Q6MVD4 Cluster: Related to glucan 1, 4-alpha-glucosidase;
n=2; Neurospora crassa|Rep: Related to glucan 1,
4-alpha-glucosidase - Neurospora crassa
Length = 1625
Score = 33.5 bits (73), Expect = 5.3
Identities = 21/73 (28%), Positives = 31/73 (42%)
Frame = -2
Query: 711 SXACVMYEARTPQSNTRGASGPINIATAPAPPVGLAGPFP*TAMSPATTMAFLPSQDEDS 532
S A V + + T A PI +TAP+ P G AG +P+++ + PS
Sbjct: 1411 STASVSSGSSYSSAETTSAPYPITNSTAPSSPTGTAGSSSSPLFTPSSSSSSGPSASSTG 1470
Query: 531 TQFMALKRAAVPP 493
+ AL V P
Sbjct: 1471 SSSTALTSGTVTP 1483
>UniRef50_UPI0000E4A4E5 Cluster: PREDICTED: similar to scavenger
receptor cysteine-rich protein precursor; n=3;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
scavenger receptor cysteine-rich protein precursor -
Strongylocentrotus purpuratus
Length = 1020
Score = 33.1 bits (72), Expect = 7.0
Identities = 24/75 (32%), Positives = 36/75 (48%), Gaps = 6/75 (8%)
Frame = +2
Query: 278 CSDREDINSICLTALHRL--IDKQKINLHDIGRLEVGT----ETIIDKSKSVKTFLMTLF 439
C+ ED + IC+ RL + K K+ L D G L V E+ D +++ T L
Sbjct: 370 CAHNEDASVICIPKERRLTRLSKNKL-LEDEGELSVPKNPQCESTHDDIETIFTSKTALL 428
Query: 440 AKEGATDIEGIDTTN 484
AK+G+TD + N
Sbjct: 429 AKDGSTDAMSLSVEN 443
>UniRef50_Q8EY21 Cluster: NADH dehydrogenase; n=4; Leptospira|Rep:
NADH dehydrogenase - Leptospira interrogans
Length = 422
Score = 33.1 bits (72), Expect = 7.0
Identities = 16/34 (47%), Positives = 18/34 (52%)
Frame = +2
Query: 548 DGRKAIVVAGDIAVYGKGPARPTGGAGAVAMLIG 649
+G + V GDIA Y KG RP G VAM G
Sbjct: 292 EGHSEVFVIGDIASYSKGLERPLPGVSPVAMQQG 325
>UniRef50_A7LTP0 Cluster: Putative uncharacterized protein; n=1;
Bacteroides ovatus ATCC 8483|Rep: Putative
uncharacterized protein - Bacteroides ovatus ATCC 8483
Length = 594
Score = 33.1 bits (72), Expect = 7.0
Identities = 20/46 (43%), Positives = 28/46 (60%), Gaps = 1/46 (2%)
Frame = +2
Query: 449 GATD-IEGIDTTNACYGGTAALFNAINWVESSSWDGRKAIVVAGDI 583
GAT+ +E I +NAC G +AL A W+ES + ++ IV GDI
Sbjct: 139 GATNQVEVI--SNACISGVSALIVAKRWIESGRY--KRVIVAGGDI 180
>UniRef50_A4AX52 Cluster: Putative ABC-type transport system, ATPase
component; n=4; Gammaproteobacteria|Rep: Putative
ABC-type transport system, ATPase component -
Alteromonas macleodii 'Deep ecotype'
Length = 344
Score = 33.1 bits (72), Expect = 7.0
Identities = 24/70 (34%), Positives = 34/70 (48%), Gaps = 5/70 (7%)
Frame = +2
Query: 461 IEGIDTTNACYGGTAALFNAINWVE----SSSWDGRKAIVVAGDIAVYGKGPARPTGGA- 625
+E +DT ACY A+ F A E S+++D +A + GK P P GA
Sbjct: 205 LEQLDTPEACYSSPASRFVARFMGEASFLSATFDASEADTDKTVVTEIGKVPGTPLQGAN 264
Query: 626 GAVAMLIGPD 655
G V +L+ PD
Sbjct: 265 GNVDLLVRPD 274
>UniRef50_A3TWG2 Cluster: Methionine sulfoxide reductase B; n=1;
Oceanicola batsensis HTCC2597|Rep: Methionine sulfoxide
reductase B - Oceanicola batsensis HTCC2597
Length = 173
Score = 33.1 bits (72), Expect = 7.0
Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 1/68 (1%)
Frame = +2
Query: 368 RLEVGTETIIDKSKSVKTFLMTLFAKEGATDIEGIDTTNACYGGTAALFNAIN-WVESSS 544
R + T T +D S SV L T E ATDIEG+D++ Y T + + W + +
Sbjct: 70 RADSQTVTEVDSSTSVPASLETSRLAE-ATDIEGMDSSREMYIWTMNDVDGVEPWSDEDA 128
Query: 545 WDGRKAIV 568
+ R AIV
Sbjct: 129 TEMRSAIV 136
>UniRef50_A3J8N4 Cluster: Hydrolase of the alpha/beta superfamily
protein; n=1; Marinobacter sp. ELB17|Rep: Hydrolase of
the alpha/beta superfamily protein - Marinobacter sp.
ELB17
Length = 370
Score = 33.1 bits (72), Expect = 7.0
Identities = 17/48 (35%), Positives = 26/48 (54%)
Frame = +2
Query: 518 AINWVESSSWDGRKAIVVAGDIAVYGKGPARPTGGAGAVAMLIGPDAP 661
A+NW+E S + GR+ ++ G + G+ AGA+ LI DAP
Sbjct: 178 AVNWIEQSRYSGRQRMMAEG---LSGQEIEAAEDAAGAINALIQSDAP 222
>UniRef50_Q6K4B4 Cluster: Putative uncharacterized protein
OJ1509_C06.33; n=1; Oryza sativa (japonica
cultivar-group)|Rep: Putative uncharacterized protein
OJ1509_C06.33 - Oryza sativa subsp. japonica (Rice)
Length = 83
Score = 33.1 bits (72), Expect = 7.0
Identities = 18/47 (38%), Positives = 24/47 (51%)
Frame = -2
Query: 681 TPQSNTRGASGPINIATAPAPPVGLAGPFP*TAMSPATTMAFLPSQD 541
+P T GA+ A +PAPP G AG A +PATT P ++
Sbjct: 4 SPWPPTTGAASAAAAAASPAPPEGAAGGAATPAAAPATTSEQRPVKE 50
>UniRef50_Q6RCQ7 Cluster: SdeD; n=11; Legionella pneumophila|Rep:
SdeD - Legionella pneumophila
Length = 397
Score = 32.7 bits (71), Expect = 9.3
Identities = 28/99 (28%), Positives = 45/99 (45%), Gaps = 9/99 (9%)
Frame = +2
Query: 359 DIGRLEVGTETIIDKSKSVKTFLMTLFAKEGATDIEGIDTTNACYGGTAALFNAINWVES 538
D+ R + E + SK V + TL G D G+D + G AA A+ +++S
Sbjct: 207 DLMRCKSPVEVFLGHSKGVSGIVPTLIHLFGKQD--GLDIMHYARGLFAATGEAVPYIDS 264
Query: 539 SSWDG--------RKAIVVAGDIAVYG-KGPARPTGGAG 628
S W ++A+ + GDI V G + ++ T AG
Sbjct: 265 SEWPHLGVDLSRVQRALSIVGDINVPGQEADSKKTAQAG 303
>UniRef50_Q0RBP5 Cluster: Putative uncharacterized protein; n=1;
Frankia alni ACN14a|Rep: Putative uncharacterized
protein - Frankia alni (strain ACN14a)
Length = 727
Score = 32.7 bits (71), Expect = 9.3
Identities = 19/73 (26%), Positives = 30/73 (41%)
Frame = +2
Query: 464 EGIDTTNACYGGTAALFNAINWVESSSWDGRKAIVVAGDIAVYGKGPARPTGGAGAVAML 643
+G T C G AL ++ E S + AG I +GP G AG + +
Sbjct: 247 DGYLTRRRCADGATALDELVDERELPSRAAPGCLPAAGGILAAARGPTSDEGAAGCLPID 306
Query: 644 IGPDAPLVFDCGV 682
GP ++ + G+
Sbjct: 307 CGPAGDVLIESGL 319
>UniRef50_A3I6K4 Cluster: Putative uncharacterized protein; n=1;
Bacillus sp. B14905|Rep: Putative uncharacterized
protein - Bacillus sp. B14905
Length = 439
Score = 32.7 bits (71), Expect = 9.3
Identities = 18/59 (30%), Positives = 31/59 (52%), Gaps = 2/59 (3%)
Frame = +2
Query: 143 VENVGILAMELYFPSQYV-DQT-ELEKFDEVSTGKYTIGLGQSKMGFCSDREDINSICL 313
+ N + +++Y Q+ DQ E++K D V T T+G+ S F DR+ +S+ L
Sbjct: 54 LSNETVTKIQVYGDKQFTEDQVQEIKKIDHVETVLETVGMNASVHSFLGDRDSTSSLIL 112
>UniRef50_A0Z706 Cluster: Putative uncharacterized protein; n=1;
marine gamma proteobacterium HTCC2080|Rep: Putative
uncharacterized protein - marine gamma proteobacterium
HTCC2080
Length = 1325
Score = 32.7 bits (71), Expect = 9.3
Identities = 20/58 (34%), Positives = 25/58 (43%)
Frame = +2
Query: 416 KTFLMTLFAKEGATDIEGIDTTNACYGGTAALFNAINWVESSSWDGRKAIVVAGDIAV 589
+T + T A E AT G DT GGTAA + A + V S + GD V
Sbjct: 187 ETTVFTTAASETATVTLGDDTVTGTVGGTAATYAATDTVADKSSGDSDTFTITGDANV 244
>UniRef50_A3BZV3 Cluster: Putative uncharacterized protein; n=1;
Oryza sativa (japonica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. japonica
(Rice)
Length = 141
Score = 32.7 bits (71), Expect = 9.3
Identities = 17/39 (43%), Positives = 21/39 (53%)
Frame = -2
Query: 681 TPQSNTRGASGPINIATAPAPPVGLAGPFP*TAMSPATT 565
+P T GA+ A +PAPP G AG A +PATT
Sbjct: 4 SPWPPTTGAASAAAAAASPAPPEGAAGGAATPAAAPATT 42
>UniRef50_Q4Y427 Cluster: Putative uncharacterized protein; n=1;
Plasmodium chabaudi|Rep: Putative uncharacterized
protein - Plasmodium chabaudi
Length = 61
Score = 32.7 bits (71), Expect = 9.3
Identities = 15/30 (50%), Positives = 19/30 (63%)
Frame = -1
Query: 217 FF*FSLINVLRREIKFHGEYAYILNFSAHI 128
FF FS I++ R E KF EY Y+ S+HI
Sbjct: 15 FFFFSKISISRLEKKFENEYGYLKFLSSHI 44
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 692,828,066
Number of Sequences: 1657284
Number of extensions: 13753170
Number of successful extensions: 41066
Number of sequences better than 10.0: 59
Number of HSP's better than 10.0 without gapping: 38826
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 40922
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 57851245060
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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