Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P04_F_I10
(751 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC080593-1|AAH80593.1| 449|Homo sapiens SAMD8 protein protein. 113 8e-25
AL392111-3|CAI40906.1| 478|Homo sapiens sterile alpha motif dom... 113 8e-25
AL392111-6|CAI40909.1| 326|Homo sapiens sterile alpha motif dom... 112 1e-24
AL392111-5|CAI40908.1| 254|Homo sapiens sterile alpha motif dom... 112 1e-24
AK057811-1|BAB71586.1| 326|Homo sapiens protein ( Homo sapiens ... 112 1e-24
BC042899-1|AAH42899.1| 413|Homo sapiens sphingomyelin synthase ... 70 8e-12
AY332650-1|AAQ22363.1| 283|Homo sapiens MOB protein protein. 70 8e-12
AY280959-1|AAP37279.1| 413|Homo sapiens MOB protein protein. 70 8e-12
AB154421-1|BAD16809.1| 413|Homo sapiens sphingomyelin synthase ... 70 8e-12
BC041369-1|AAH41369.1| 365|Homo sapiens sphingomyelin synthase ... 61 5e-09
BC028705-1|AAH28705.1| 365|Homo sapiens MGC26963 protein protein. 61 5e-09
AK001985-1|BAA92020.1| 531|Homo sapiens protein ( Homo sapiens ... 33 1.1
BC013402-1|AAH13402.1| 531|Homo sapiens Paf1, RNA polymerase II... 32 1.9
BC000017-1|AAH00017.1| 531|Homo sapiens Paf1, RNA polymerase II... 32 1.9
AJ401156-1|CAC20564.1| 531|Homo sapiens PD2 protein protein. 32 1.9
AC005239-1|AAC25503.1| 510|Homo sapiens F23149_1 protein. 32 1.9
AK098423-1|BAC05305.1| 485|Homo sapiens protein ( Homo sapiens ... 31 4.4
>BC080593-1|AAH80593.1| 449|Homo sapiens SAMD8 protein protein.
Length = 449
Score = 113 bits (271), Expect = 8e-25
Identities = 68/223 (30%), Positives = 106/223 (47%), Gaps = 4/223 (1%)
Frame = +1
Query: 94 EEYSETMESDILNWGNKEVEELLHKENISSCLIEICKTHDIDGPCLLSFVDRDFHTHPFD 273
EE + + I W K V L E + +C H +DG LL+ + D + P +
Sbjct: 33 EEMAGPNQLCIRRWTTKHVAVWLKDEGFFEYVDILCNKHRLDGITLLTLTEYDLRSPPLE 92
Query: 274 QLKLGERKRFILLVKKLQRHNRSAMMELGLCDDLINPATNINFLGTNLSHLSYDLHNKIP 453
LG+ KR +L V+KLQ+ + + E+G D +P ++ + L + + ++
Sbjct: 93 IKVLGDIKRLMLSVRKLQKIHIDVLEEMGYNSD--SPMGSMTPFISALQSTDWLCNGELS 150
Query: 454 NELSFAGNTECVSSYPPADIK----ASKLRPEVWKTAIALGYXXXXXXXXXXXXXXXHDK 621
++ Y + K +L PE WKT ++ Y H++
Sbjct: 151 HDCDGPITDLNSDQYQYMNGKNKHSVRRLDPEYWKTILSCIYVFIVFGFTSFIMVIVHER 210
Query: 622 VPDMKKYPPLPDLFLDNVPHIPWAFDMCEITGSLLMAIWLIXL 750
VPDM+ YPPLPD+FLD+VP IPWAF M E+ G +L IWL+ L
Sbjct: 211 VPDMQTYPPLPDIFLDSVPRIPWAFAMTEVCGMILCYIWLLVL 253
>AL392111-3|CAI40906.1| 478|Homo sapiens sterile alpha motif domain
containing 8 protein.
Length = 478
Score = 113 bits (271), Expect = 8e-25
Identities = 68/223 (30%), Positives = 106/223 (47%), Gaps = 4/223 (1%)
Frame = +1
Query: 94 EEYSETMESDILNWGNKEVEELLHKENISSCLIEICKTHDIDGPCLLSFVDRDFHTHPFD 273
EE + + I W K V L E + +C H +DG LL+ + D + P +
Sbjct: 62 EEMAGPNQLCIRRWTTKHVAVWLKDEGFFEYVDILCNKHRLDGITLLTLTEYDLRSPPLE 121
Query: 274 QLKLGERKRFILLVKKLQRHNRSAMMELGLCDDLINPATNINFLGTNLSHLSYDLHNKIP 453
LG+ KR +L V+KLQ+ + + E+G D +P ++ + L + + ++
Sbjct: 122 IKVLGDIKRLMLSVRKLQKIHIDVLEEMGYNSD--SPMGSMTPFISALQSTDWLCNGELS 179
Query: 454 NELSFAGNTECVSSYPPADIK----ASKLRPEVWKTAIALGYXXXXXXXXXXXXXXXHDK 621
++ Y + K +L PE WKT ++ Y H++
Sbjct: 180 HDCDGPITDLNSDQYQYMNGKNKHSVRRLDPEYWKTILSCIYVFIVFGFTSFIMVIVHER 239
Query: 622 VPDMKKYPPLPDLFLDNVPHIPWAFDMCEITGSLLMAIWLIXL 750
VPDM+ YPPLPD+FLD+VP IPWAF M E+ G +L IWL+ L
Sbjct: 240 VPDMQTYPPLPDIFLDSVPRIPWAFAMTEVCGMILCYIWLLVL 282
>AL392111-6|CAI40909.1| 326|Homo sapiens sterile alpha motif domain
containing 8 protein.
Length = 326
Score = 112 bits (269), Expect = 1e-24
Identities = 66/213 (30%), Positives = 102/213 (47%), Gaps = 4/213 (1%)
Frame = +1
Query: 124 ILNWGNKEVEELLHKENISSCLIEICKTHDIDGPCLLSFVDRDFHTHPFDQLKLGERKRF 303
I W K V L E + +C H +DG LL+ + D + P + LG+ KR
Sbjct: 9 IRRWTTKHVAVWLKDEGFFEYVDILCNKHRLDGITLLTLTEYDLRSPPLEIKVLGDIKRL 68
Query: 304 ILLVKKLQRHNRSAMMELGLCDDLINPATNINFLGTNLSHLSYDLHNKIPNELSFAGNTE 483
+L V+KLQ+ + + E+G D +P ++ + L + + ++ ++
Sbjct: 69 MLSVRKLQKIHIDVLEEMGYNSD--SPMGSMTPFISALQSTDWLCNGELSHDCDGPITDL 126
Query: 484 CVSSYPPADIK----ASKLRPEVWKTAIALGYXXXXXXXXXXXXXXXHDKVPDMKKYPPL 651
Y + K +L PE WKT ++ Y H++VPDM+ YPPL
Sbjct: 127 NSDQYQYMNGKNKHSVRRLDPEYWKTILSCIYVFIVFGFTSFIMVIVHERVPDMQTYPPL 186
Query: 652 PDLFLDNVPHIPWAFDMCEITGSLLMAIWLIXL 750
PD+FLD+VP IPWAF M E+ G +L IWL+ L
Sbjct: 187 PDIFLDSVPRIPWAFAMTEVCGMILCYIWLLVL 219
>AL392111-5|CAI40908.1| 254|Homo sapiens sterile alpha motif domain
containing 8 protein.
Length = 254
Score = 112 bits (269), Expect = 1e-24
Identities = 66/213 (30%), Positives = 102/213 (47%), Gaps = 4/213 (1%)
Frame = +1
Query: 124 ILNWGNKEVEELLHKENISSCLIEICKTHDIDGPCLLSFVDRDFHTHPFDQLKLGERKRF 303
I W K V L E + +C H +DG LL+ + D + P + LG+ KR
Sbjct: 9 IRRWTTKHVAVWLKDEGFFEYVDILCNKHRLDGITLLTLTEYDLRSPPLEIKVLGDIKRL 68
Query: 304 ILLVKKLQRHNRSAMMELGLCDDLINPATNINFLGTNLSHLSYDLHNKIPNELSFAGNTE 483
+L V+KLQ+ + + E+G D +P ++ + L + + ++ ++
Sbjct: 69 MLSVRKLQKIHIDVLEEMGYNSD--SPMGSMTPFISALQSTDWLCNGELSHDCDGPITDL 126
Query: 484 CVSSYPPADIK----ASKLRPEVWKTAIALGYXXXXXXXXXXXXXXXHDKVPDMKKYPPL 651
Y + K +L PE WKT ++ Y H++VPDM+ YPPL
Sbjct: 127 NSDQYQYMNGKNKHSVRRLDPEYWKTILSCIYVFIVFGFTSFIMVIVHERVPDMQTYPPL 186
Query: 652 PDLFLDNVPHIPWAFDMCEITGSLLMAIWLIXL 750
PD+FLD+VP IPWAF M E+ G +L IWL+ L
Sbjct: 187 PDIFLDSVPRIPWAFAMTEVCGMILCYIWLLVL 219
>AK057811-1|BAB71586.1| 326|Homo sapiens protein ( Homo sapiens
cDNA FLJ25082 fis, clone CBL07772. ).
Length = 326
Score = 112 bits (269), Expect = 1e-24
Identities = 66/213 (30%), Positives = 102/213 (47%), Gaps = 4/213 (1%)
Frame = +1
Query: 124 ILNWGNKEVEELLHKENISSCLIEICKTHDIDGPCLLSFVDRDFHTHPFDQLKLGERKRF 303
I W K V L E + +C H +DG LL+ + D + P + LG+ KR
Sbjct: 9 IRRWTTKHVAVWLKDEGFFEYVDILCNKHRLDGITLLTLTEYDLRSPPLEIKVLGDIKRL 68
Query: 304 ILLVKKLQRHNRSAMMELGLCDDLINPATNINFLGTNLSHLSYDLHNKIPNELSFAGNTE 483
+L V+KLQ+ + + E+G D +P ++ + L + + ++ ++
Sbjct: 69 MLSVRKLQKIHIDVLEEMGYNSD--SPMGSMTPFISALQSTDWLCNGELSHDCDGPITDL 126
Query: 484 CVSSYPPADIK----ASKLRPEVWKTAIALGYXXXXXXXXXXXXXXXHDKVPDMKKYPPL 651
Y + K +L PE WKT ++ Y H++VPDM+ YPPL
Sbjct: 127 NSDQYQYMNGKNKHSVRRLDPEYWKTILSCIYVFIVFGFTSFIMVIVHERVPDMQTYPPL 186
Query: 652 PDLFLDNVPHIPWAFDMCEITGSLLMAIWLIXL 750
PD+FLD+VP IPWAF M E+ G +L IWL+ L
Sbjct: 187 PDIFLDSVPRIPWAFAMTEVCGMILCYIWLLVL 219
>BC042899-1|AAH42899.1| 413|Homo sapiens sphingomyelin synthase 1
protein.
Length = 413
Score = 70.1 bits (164), Expect = 8e-12
Identities = 49/209 (23%), Positives = 92/209 (44%), Gaps = 1/209 (0%)
Frame = +1
Query: 121 DILNWGNKEVEELLHKENISSCLIEICKTHD-IDGPCLLSFVDRDFHTHPFDQLKLGERK 297
+++ W K+V + L + + + E C+ + G L++ DF P ++ +
Sbjct: 3 EVVYWSPKKVADWL----LENAMPEYCEPLEHFTGQDLINLTQEDFKKPPLCRVSSDNGQ 58
Query: 298 RFILLVKKLQRHNRSAMMELGLCDDLINPATNINFLGTNLSHLSYDLHNKIPNELSFAGN 477
R + +++ L+ + + G + +N +I S+ + K PN +
Sbjct: 59 RLLDMIETLKMEHHLEAHKNGHANGHLNIGVDIP-----TPDGSFSIKIK-PNGMPNGYR 112
Query: 478 TECVSSYPPADIKASKLRPEVWKTAIALGYXXXXXXXXXXXXXXXHDKVPDMKKYPPLPD 657
E + P +++ S+ E KT +A Y H++VP + PPLPD
Sbjct: 113 KEMIK-IPMPELERSQYPMEWGKTFLAFLYALSCFVLTTVMISVVHERVPPKEVQPPLPD 171
Query: 658 LFLDNVPHIPWAFDMCEITGSLLMAIWLI 744
F D+ + WAF +CEI G +L+ +WLI
Sbjct: 172 TFFDHFNRVQWAFSICEINGMILVGLWLI 200
>AY332650-1|AAQ22363.1| 283|Homo sapiens MOB protein protein.
Length = 283
Score = 70.1 bits (164), Expect = 8e-12
Identities = 49/209 (23%), Positives = 92/209 (44%), Gaps = 1/209 (0%)
Frame = +1
Query: 121 DILNWGNKEVEELLHKENISSCLIEICKTHD-IDGPCLLSFVDRDFHTHPFDQLKLGERK 297
+++ W K+V + L + + + E C+ + G L++ DF P ++ +
Sbjct: 3 EVVYWSPKKVADWL----LENAMPEYCEPLEHFTGQDLINLTQEDFKKPPLCRVSSDNGQ 58
Query: 298 RFILLVKKLQRHNRSAMMELGLCDDLINPATNINFLGTNLSHLSYDLHNKIPNELSFAGN 477
R + +++ L+ + + G + +N +I S+ + K PN +
Sbjct: 59 RLLDMIETLKMEHHLEAHKNGHANGHLNIGVDIP-----TPDGSFSIKIK-PNGMPNGYR 112
Query: 478 TECVSSYPPADIKASKLRPEVWKTAIALGYXXXXXXXXXXXXXXXHDKVPDMKKYPPLPD 657
E + P +++ S+ E KT +A Y H++VP + PPLPD
Sbjct: 113 KEMIK-IPMPELERSQYPMEWGKTFLAFLYALSCFVLTTVMISVVHERVPPKEVQPPLPD 171
Query: 658 LFLDNVPHIPWAFDMCEITGSLLMAIWLI 744
F D+ + WAF +CEI G +L+ +WLI
Sbjct: 172 TFFDHFNRVQWAFSICEINGMILVGLWLI 200
>AY280959-1|AAP37279.1| 413|Homo sapiens MOB protein protein.
Length = 413
Score = 70.1 bits (164), Expect = 8e-12
Identities = 49/209 (23%), Positives = 92/209 (44%), Gaps = 1/209 (0%)
Frame = +1
Query: 121 DILNWGNKEVEELLHKENISSCLIEICKTHD-IDGPCLLSFVDRDFHTHPFDQLKLGERK 297
+++ W K+V + L + + + E C+ + G L++ DF P ++ +
Sbjct: 3 EVVYWSPKKVADWL----LENAMPEYCEPLEHFTGQDLINLTQEDFKKPPLCRVSSDNGQ 58
Query: 298 RFILLVKKLQRHNRSAMMELGLCDDLINPATNINFLGTNLSHLSYDLHNKIPNELSFAGN 477
R + +++ L+ + + G + +N +I S+ + K PN +
Sbjct: 59 RLLDMIETLKMEHHLEAHKNGHANGHLNIGVDIP-----TPDGSFSIKIK-PNGMPNGYR 112
Query: 478 TECVSSYPPADIKASKLRPEVWKTAIALGYXXXXXXXXXXXXXXXHDKVPDMKKYPPLPD 657
E + P +++ S+ E KT +A Y H++VP + PPLPD
Sbjct: 113 KEMIK-IPMPELERSQYPMEWGKTFLAFLYALSCFVLTTVMISVVHERVPPKEVQPPLPD 171
Query: 658 LFLDNVPHIPWAFDMCEITGSLLMAIWLI 744
F D+ + WAF +CEI G +L+ +WLI
Sbjct: 172 TFFDHFNRVQWAFSICEINGMILVGLWLI 200
>AB154421-1|BAD16809.1| 413|Homo sapiens sphingomyelin synthase
protein.
Length = 413
Score = 70.1 bits (164), Expect = 8e-12
Identities = 49/209 (23%), Positives = 92/209 (44%), Gaps = 1/209 (0%)
Frame = +1
Query: 121 DILNWGNKEVEELLHKENISSCLIEICKTHD-IDGPCLLSFVDRDFHTHPFDQLKLGERK 297
+++ W K+V + L + + + E C+ + G L++ DF P ++ +
Sbjct: 3 EVVYWSPKKVADWL----LENAMPEYCEPLEHFTGQDLINLTQEDFKKPPLCRVSSDNGQ 58
Query: 298 RFILLVKKLQRHNRSAMMELGLCDDLINPATNINFLGTNLSHLSYDLHNKIPNELSFAGN 477
R + +++ L+ + + G + +N +I S+ + K PN +
Sbjct: 59 RLLDMIETLKMEHHLEAHKNGHANGHLNIGVDIP-----TPDGSFSIKIK-PNGMPNGYR 112
Query: 478 TECVSSYPPADIKASKLRPEVWKTAIALGYXXXXXXXXXXXXXXXHDKVPDMKKYPPLPD 657
E + P +++ S+ E KT +A Y H++VP + PPLPD
Sbjct: 113 KEMIK-IPMPELERSQYPMEWGKTFLAFLYALSCFVLTTVMISVVHERVPPKEVQPPLPD 171
Query: 658 LFLDNVPHIPWAFDMCEITGSLLMAIWLI 744
F D+ + WAF +CEI G +L+ +WLI
Sbjct: 172 TFFDHFNRVQWAFSICEINGMILVGLWLI 200
>BC041369-1|AAH41369.1| 365|Homo sapiens sphingomyelin synthase 2
protein.
Length = 365
Score = 60.9 bits (141), Expect = 5e-09
Identities = 26/74 (35%), Positives = 37/74 (50%)
Frame = +1
Query: 520 SKLRPEVWKTAIALGYXXXXXXXXXXXXXXXHDKVPDMKKYPPLPDLFLDNVPHIPWAFD 699
+K E WKT IA Y H++VP + PPLPD F D + + WAF
Sbjct: 70 NKFPLEWWKTGIAFIYAVFNLVLTTVMITVVHERVPPKELSPPLPDKFFDYIDRVKWAFS 129
Query: 700 MCEITGSLLMAIWL 741
+ EI G +L+ +W+
Sbjct: 130 VSEINGIILVGLWI 143
>BC028705-1|AAH28705.1| 365|Homo sapiens MGC26963 protein protein.
Length = 365
Score = 60.9 bits (141), Expect = 5e-09
Identities = 26/74 (35%), Positives = 37/74 (50%)
Frame = +1
Query: 520 SKLRPEVWKTAIALGYXXXXXXXXXXXXXXXHDKVPDMKKYPPLPDLFLDNVPHIPWAFD 699
+K E WKT IA Y H++VP + PPLPD F D + + WAF
Sbjct: 70 NKFPLEWWKTGIAFIYAVFNLVLTTVMITVVHERVPPKELSPPLPDKFFDYIDRVKWAFS 129
Query: 700 MCEITGSLLMAIWL 741
+ EI G +L+ +W+
Sbjct: 130 VSEINGIILVGLWI 143
>AK001985-1|BAA92020.1| 531|Homo sapiens protein ( Homo sapiens
cDNA FLJ11123 fis, clone PLACE1006167. ).
Length = 531
Score = 33.1 bits (72), Expect = 1.1
Identities = 19/49 (38%), Positives = 28/49 (57%)
Frame = +1
Query: 244 DRDFHTHPFDQLKLGERKRFILLVKKLQRHNRSAMMELGLCDDLINPAT 390
D F T+PFDQ ++ + K L +K +H+ +LG+ DLINP T
Sbjct: 45 DPKFITYPFDQNRIVQYKATSL--EKQHKHDLLTEPDLGVTIDLINPDT 91
>BC013402-1|AAH13402.1| 531|Homo sapiens Paf1, RNA polymerase II
associated factor, homolog (S. cerevisiae) protein.
Length = 531
Score = 32.3 bits (70), Expect = 1.9
Identities = 19/49 (38%), Positives = 27/49 (55%)
Frame = +1
Query: 244 DRDFHTHPFDQLKLGERKRFILLVKKLQRHNRSAMMELGLCDDLINPAT 390
D F T+PFDQ + + K L +K +H+ +LG+ DLINP T
Sbjct: 45 DPKFITYPFDQNRFVQYKATSL--EKQHKHDLLTEPDLGVTIDLINPDT 91
>BC000017-1|AAH00017.1| 531|Homo sapiens Paf1, RNA polymerase II
associated factor, homolog (S. cerevisiae) protein.
Length = 531
Score = 32.3 bits (70), Expect = 1.9
Identities = 19/49 (38%), Positives = 27/49 (55%)
Frame = +1
Query: 244 DRDFHTHPFDQLKLGERKRFILLVKKLQRHNRSAMMELGLCDDLINPAT 390
D F T+PFDQ + + K L +K +H+ +LG+ DLINP T
Sbjct: 45 DPKFITYPFDQNRFVQYKATSL--EKQHKHDLLTEPDLGVTIDLINPDT 91
>AJ401156-1|CAC20564.1| 531|Homo sapiens PD2 protein protein.
Length = 531
Score = 32.3 bits (70), Expect = 1.9
Identities = 19/49 (38%), Positives = 27/49 (55%)
Frame = +1
Query: 244 DRDFHTHPFDQLKLGERKRFILLVKKLQRHNRSAMMELGLCDDLINPAT 390
D F T+PFDQ + + K L +K +H+ +LG+ DLINP T
Sbjct: 45 DPKFITYPFDQNRFVQYKATSL--EKQHKHDLLTEPDLGVTIDLINPDT 91
>AC005239-1|AAC25503.1| 510|Homo sapiens F23149_1 protein.
Length = 510
Score = 32.3 bits (70), Expect = 1.9
Identities = 19/49 (38%), Positives = 27/49 (55%)
Frame = +1
Query: 244 DRDFHTHPFDQLKLGERKRFILLVKKLQRHNRSAMMELGLCDDLINPAT 390
D F T+PFDQ + + K L +K +H+ +LG+ DLINP T
Sbjct: 35 DPKFITYPFDQNRFVQYKATSL--EKQHKHDLLTEPDLGVTIDLINPDT 81
>AK098423-1|BAC05305.1| 485|Homo sapiens protein ( Homo sapiens
cDNA FLJ25557 fis, clone JTH02756. ).
Length = 485
Score = 31.1 bits (67), Expect = 4.4
Identities = 18/49 (36%), Positives = 27/49 (55%)
Frame = +1
Query: 244 DRDFHTHPFDQLKLGERKRFILLVKKLQRHNRSAMMELGLCDDLINPAT 390
D F T+PFDQ + + K L ++ +H+ +LG+ DLINP T
Sbjct: 35 DPKFITYPFDQNRFVQYKATSL--ERQHKHDLLTEPDLGVTIDLINPDT 81
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 109,535,361
Number of Sequences: 237096
Number of extensions: 2219786
Number of successful extensions: 4050
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 3873
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4045
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 9015132854
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -