Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P04_F_E19
(724 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BT006881-1|AAP35527.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 243 4e-64
BC001470-1|AAH01470.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 243 4e-64
AF515625-1|AAM54026.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 243 4e-64
AF515624-1|AAO15991.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 243 4e-64
AF515623-1|AAN59786.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 243 4e-64
AF113123-1|AAF14864.1| 244|Homo sapiens carbonyl reductase prot... 243 4e-64
AB013846-1|BAB64299.1| 244|Homo sapiens kidney dicarbonyl reduc... 243 4e-64
AF139841-1|AAP97273.1| 244|Homo sapiens carbonyl reductase II p... 241 1e-63
BC003018-1|AAH03018.1| 243|Homo sapiens Unknown (protein for IM... 241 2e-63
DQ344810-1|ABD75823.1| 278|Homo sapiens NADP(H)-dependent retin... 100 5e-21
BC003019-1|AAH03019.1| 278|Homo sapiens dehydrogenase/reductase... 100 5e-21
AY358638-1|AAQ89001.1| 278|Homo sapiens SCAD-SRL protein. 100 5e-21
AB045131-1|BAB18775.1| 260|Homo sapiens NADPH-dependent retinol... 100 5e-21
AF064256-1|AAQ13444.1| 278|Homo sapiens Hep27-like protein prot... 99 8e-21
AF044127-1|AAD02292.1| 260|Homo sapiens peroxisomal short-chain... 99 8e-21
AK001870-1|BAA91953.1| 278|Homo sapiens protein ( Homo sapiens ... 99 1e-20
BT007239-1|AAP35903.1| 261|Homo sapiens hydroxysteroid (17-beta... 89 1e-17
BC008185-1|AAH08185.1| 261|Homo sapiens hydroxysteroid (17-beta... 89 1e-17
AL844527-12|CAI41840.1| 261|Homo sapiens hydroxysteroid (17-bet... 89 1e-17
AL713971-6|CAI17657.1| 261|Homo sapiens hydroxysteroid (17-beta... 89 1e-17
AL662824-24|CAI17616.1| 261|Homo sapiens hydroxysteroid (17-bet... 89 1e-17
AL645940-10|CAI18068.1| 261|Homo sapiens hydroxysteroid (17-bet... 89 1e-17
AL031228-10|CAC38444.1| 261|Homo sapiens hydroxysteroid (17-bet... 89 1e-17
AY358841-1|AAQ89200.1| 245|Homo sapiens GRLD6308 protein. 87 5e-17
D82061-1|BAA11529.1| 259|Homo sapiens a member of the short-cha... 87 6e-17
BC095414-1|AAH95414.1| 245|Homo sapiens 3-hydroxybutyrate dehyd... 87 6e-17
BC001953-1|AAH01953.1| 245|Homo sapiens 3-hydroxybutyrate dehyd... 87 6e-17
AF164790-1|AAF80754.1| 245|Homo sapiens oxidoreductase UCPA pro... 87 6e-17
AF126781-1|AAF06940.1| 270|Homo sapiens retinal short-chain deh... 85 2e-16
BC006294-1|AAH06294.1| 270|Homo sapiens hydroxysteroid (17-beta... 85 2e-16
BC006283-1|AAH06283.1| 270|Homo sapiens hydroxysteroid (17-beta... 85 2e-16
AY358430-1|AAQ88796.1| 270|Homo sapiens ATGT502 protein. 85 2e-16
U78302-1|AAB88724.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 81 5e-15
L26050-1|AAA67551.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 81 5e-15
BC105082-1|AAI05083.1| 335|Homo sapiens 2,4-dienoyl CoA reducta... 81 5e-15
BC105080-1|AAI05081.1| 335|Homo sapiens 2,4-dienoyl CoA reducta... 81 5e-15
AC004612-1|AAC14671.1| 335|Homo sapiens 2,4-dienoyl-CoA reducta... 81 5e-15
U49352-1|AAB09423.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 80 9e-15
U31875-1|AAA82048.1| 280|Homo sapiens Hep27 protein protein. 79 2e-14
BC007339-1|AAH07339.2| 271|Homo sapiens DHRS2 protein protein. 79 2e-14
AF244132-1|AAG33703.1| 280|Homo sapiens short-chain alcohol deh... 79 2e-14
AK222857-1|BAD96577.1| 280|Homo sapiens dehydrogenase/reductase... 78 3e-14
DQ325464-1|ABC61320.1| 244|Homo sapiens NADP(H)-dependent retin... 77 5e-14
BC033650-1|AAH33650.1| 237|Homo sapiens carbonyl reductase 4 pr... 75 3e-13
BC021973-1|AAH21973.1| 237|Homo sapiens carbonyl reductase 4 pr... 75 3e-13
BC002786-1|AAH02786.1| 300|Homo sapiens dehydrogenase/reductase... 74 5e-13
X63657-1|CAA45197.1| 332|Homo sapiens FVT1 protein. 73 1e-12
BT006782-1|AAP35428.1| 332|Homo sapiens follicular lymphoma var... 73 1e-12
BC008797-1|AAH08797.1| 332|Homo sapiens follicular lymphoma var... 73 1e-12
BC000663-1|AAH00663.2| 230|Homo sapiens dehydrogenase/reductase... 70 1e-11
BC011968-1|AAH11968.1| 244|Homo sapiens DECR2 protein protein. 69 2e-11
BC010740-1|AAH10740.1| 292|Homo sapiens 2,4-dienoyl CoA reducta... 69 2e-11
AL023881-5|CAB92744.1| 292|Homo sapiens 2,4-dienoyl CoA reducta... 69 2e-11
AL023881-4|CAI95592.1| 280|Homo sapiens 2,4-dienoyl CoA reducta... 69 2e-11
AJ293009-1|CAC05664.1| 292|Homo sapiens peroxisomal 2,4-dienoyl... 69 2e-11
AE006463-11|AAK61231.1| 292|Homo sapiens 2-4-dienoyl-Coenzyme A... 69 2e-11
BC012043-1|AAH12043.1| 312|Homo sapiens hydroxysteroid (17-beta... 66 9e-11
AK222881-1|BAD96601.1| 312|Homo sapiens steroid dehydrogenase h... 66 9e-11
U05659-1|AAC50066.1| 310|Homo sapiens 17beta-hydroxysteroid deh... 63 1e-09
CR541894-1|CAG46692.1| 310|Homo sapiens HSD17B3 protein. 63 1e-09
BC034281-1|AAH34281.1| 310|Homo sapiens hydroxysteroid (17-beta... 63 1e-09
AY341031-1|AAP88937.1| 310|Homo sapiens hydroxysteroid (17-beta... 63 1e-09
AL160269-3|CAH71615.1| 310|Homo sapiens hydroxysteroid (17-beta... 63 1e-09
BC002529-1|AAH02529.1| 303|Homo sapiens peroxisomal trans-2-eno... 62 2e-09
AF232009-1|AAF69798.1| 303|Homo sapiens peroxisomal trans 2-eno... 62 2e-09
AF212234-1|AAK14920.1| 322|Homo sapiens HPDHase protein. 62 2e-09
AC010686-2|AAY14657.1| 303|Homo sapiens unknown protein. 62 2e-09
BC104218-1|AAI04219.1| 330|Homo sapiens hydroxysteroid dehydrog... 62 3e-09
AY028377-1|AAK16927.1| 309|Homo sapiens steroid dehydrogenase-l... 62 3e-09
AK074878-1|BAC11262.1| 330|Homo sapiens protein ( Homo sapiens ... 62 3e-09
AF237684-1|AAK15047.1| 309|Homo sapiens steroid dehydrogenase-l... 62 3e-09
BC002731-1|AAH02731.2| 260|Homo sapiens short-chain dehydrogena... 61 3e-09
AY358712-1|AAQ89074.1| 260|Homo sapiens ARPG836 protein. 61 3e-09
DQ088988-1|AAZ85982.1| 118|Homo sapiens DHRS4L2 isoform 2 protein. 60 6e-09
BC106917-1|AAI06918.1| 330|Homo sapiens hydroxysteroid dehydrog... 60 6e-09
BC104219-1|AAI04220.1| 330|Homo sapiens hydroxysteroid dehydrog... 60 6e-09
BC018084-1|AAH18084.2| 330|Homo sapiens hydroxysteroid dehydrog... 60 1e-08
AJ250303-1|CAB89810.1| 303|Homo sapiens peroxisomal 2-enoyl-CoA... 59 2e-08
AB083038-1|BAB91014.1| 309|Homo sapiens retinal short chain deh... 58 2e-08
BC064525-1|AAH64525.1| 309|Homo sapiens epidermal retinal dehyd... 58 3e-08
BC037219-1|AAH37219.2| 309|Homo sapiens epidermal retinal dehyd... 58 3e-08
Z97054-8|CAI42653.1| 261|Homo sapiens hydroxysteroid (17-beta) ... 57 7e-08
U96132-1|AAC51812.1| 261|Homo sapiens amyloid beta-peptide bind... 57 7e-08
U73514-1|AAB68958.1| 261|Homo sapiens short-chain alcohol dehyd... 57 7e-08
CR457124-1|CAG33405.1| 325|Homo sapiens DKFZp566O084 protein. 57 7e-08
CR456723-1|CAG33004.1| 261|Homo sapiens HADH2 protein. 57 7e-08
BC009679-1|AAH09679.1| 325|Homo sapiens dehydrogenase/reductase... 57 7e-08
BC004126-1|AAH04126.1| 325|Homo sapiens dehydrogenase/reductase... 57 7e-08
BC000372-1|AAH00372.1| 261|Homo sapiens hydroxysteroid (17-beta... 57 7e-08
AY358498-1|AAQ88862.1| 310|Homo sapiens DFIT212 protein. 57 7e-08
AY092415-1|AAM18189.1| 196|Homo sapiens endoplasmic reticulum-a... 57 7e-08
AF151851-1|AAD34088.1| 291|Homo sapiens CGI-93 protein protein. 57 7e-08
AF069134-1|AAC39900.1| 261|Homo sapiens putative short-chain ty... 57 7e-08
AF037438-1|AAC16419.1| 261|Homo sapiens 17beta-hydroxysteroid d... 57 7e-08
AF035555-1|AAC15902.1| 261|Homo sapiens 17beta-hydroxysteroid d... 57 7e-08
CR457356-1|CAG33637.1| 181|Homo sapiens MGC4172 protein. 56 1e-07
AK057667-1|BAB71545.1| 231|Homo sapiens protein ( Homo sapiens ... 56 1e-07
AK026196-1|BAB15390.1| 181|Homo sapiens protein ( Homo sapiens ... 56 1e-07
BT019371-1|AAV38178.1| 260|Homo sapiens hydroxysteroid (17-beta... 56 2e-07
L76465-1|AAA89175.1| 266|Homo sapiens NAD+-dependent 15-hydroxy... 55 2e-07
J05594-1|AAA89174.1| 266|Homo sapiens NAD+-dependent 15-hydroxy... 55 2e-07
AF229845-1|AAF63160.1| 311|Homo sapiens photoreceptor outer seg... 55 2e-07
DQ903072-1|ABI75347.1| 266|Homo sapiens hydroxyprostaglandin de... 54 4e-07
CR457309-1|CAG33590.1| 173|Homo sapiens DHRS6 protein. 54 4e-07
BC037277-1|AAH37277.1| 173|Homo sapiens BDH2 protein protein. 54 4e-07
BC018986-1|AAH18986.1| 266|Homo sapiens hydroxyprostaglandin de... 54 4e-07
AK023323-1|BAB14526.1| 173|Homo sapiens protein ( Homo sapiens ... 54 4e-07
AK027882-1|BAB55429.1| 177|Homo sapiens protein ( Homo sapiens ... 52 2e-06
AY186250-1|AAO72314.1| 264|Homo sapiens 17-beta hydroxysteroid ... 49 1e-05
BC036001-1|AAH36001.1| 300|Homo sapiens hydroxysteroid (17-beta... 49 2e-05
BC021673-1|AAH21673.1| 300|Homo sapiens hydroxysteroid (17-beta... 49 2e-05
BC016367-1|AAH16367.1| 300|Homo sapiens hydroxysteroid (17-beta... 49 2e-05
BC014327-1|AAH14327.1| 300|Homo sapiens hydroxysteroid (17-beta... 49 2e-05
AY358553-1|AAQ88917.1| 300|Homo sapiens KFLL207 protein. 49 2e-05
AK075348-1|BAC11560.1| 300|Homo sapiens protein ( Homo sapiens ... 49 2e-05
AF273056-1|AAM44459.1| 300|Homo sapiens CTCL tumor antigen HD-C... 49 2e-05
AF126780-1|AAF06939.1| 300|Homo sapiens retinal short-chain deh... 49 2e-05
AY358473-1|AAQ88837.1| 331|Homo sapiens RDH13 protein. 48 3e-05
AK075392-1|BAC11591.1| 331|Homo sapiens protein ( Homo sapiens ... 48 3e-05
BC112305-1|AAI12306.1| 300|Homo sapiens hydroxysteroid (17-beta... 48 4e-05
BC112303-1|AAI12304.1| 300|Homo sapiens hydroxysteroid (17-beta... 48 4e-05
AY358575-1|AAQ88938.1| 300|Homo sapiens NIIL497 protein. 48 4e-05
AY268355-1|AAP42289.1| 300|Homo sapiens short-chain dehydrogena... 48 4e-05
AY186249-1|AAO72313.1| 300|Homo sapiens 17-beta hydroxysteroid ... 48 4e-05
AB073347-1|BAD38632.1| 300|Homo sapiens putative protein produc... 48 4e-05
L40802-1|AAC41917.1| 387|Homo sapiens 17-hydroxysteroid dehydro... 47 8e-05
L11708-1|AAA03562.1| 387|Homo sapiens 17 beta hydroxysteroid de... 47 8e-05
BC059170-1|AAH59170.1| 387|Homo sapiens hydroxysteroid (17-beta... 47 8e-05
BC009581-1|AAH09581.1| 387|Homo sapiens hydroxysteroid (17-beta... 47 8e-05
AY325910-1|AAP78485.1| 387|Homo sapiens hydroxysteroid (17-beta... 47 8e-05
AK223001-1|BAD96721.1| 387|Homo sapiens hydroxysteroid (17-beta... 47 8e-05
X13440-1|CAA31792.1| 328|Homo sapiens protein ( Human mRNA for ... 46 1e-04
U34879-1|AAD05019.1| 328|Homo sapiens 17-beta-hydroxysteroid de... 46 1e-04
M84472-1|AAB16942.1| 328|Homo sapiens 17-beta-hydroxysteroid de... 46 1e-04
M36263-1|AAA35600.1| 328|Homo sapiens protein ( Human placental... 46 1e-04
M27138-1|AAB16941.1| 328|Homo sapiens protein ( Human estradiol... 46 1e-04
BC111935-1|AAI11936.1| 328|Homo sapiens hydroxysteroid (17-beta... 46 1e-04
BC104752-1|AAI04753.1| 328|Homo sapiens hydroxysteroid (17-beta... 46 1e-04
Z97054-7|CAI42652.1| 252|Homo sapiens hydroxysteroid (17-beta) ... 46 2e-04
BC008708-1|AAH08708.1| 252|Homo sapiens hydroxysteroid (17-beta... 46 2e-04
BC014057-1|AAH14057.1| 313|Homo sapiens DHRS1 protein protein. 45 3e-04
BC008650-1|AAH08650.1| 300|Homo sapiens HSD17B11 protein protein. 45 3e-04
X82460-1|CAA57843.1| 178|Homo sapiens 15-hydroxy prostaglandin ... 44 4e-04
CR457145-1|CAG33426.1| 157|Homo sapiens PECR protein. 44 4e-04
AK027337-1|BAB55045.1| 179|Homo sapiens protein ( Homo sapiens ... 44 6e-04
BC015943-1|AAH15943.1| 313|Homo sapiens DHRS1 protein protein. 43 0.001
AK058159-1|BAB71694.1| 313|Homo sapiens protein ( Homo sapiens ... 43 0.001
AF418205-1|AAN32660.1| 313|Homo sapiens dehydrogenase/reductase... 43 0.001
U27317-1|AAB48544.1| 405|Homo sapiens 11 beta-hydroxysteroid de... 41 0.004
U26726-1|AAC50356.1| 405|Homo sapiens 11-beta-hydroxysteroid de... 41 0.004
U14631-1|AAA91969.1| 405|Homo sapiens 11 beta-hydroxysteroid de... 41 0.004
EF694683-1|ABS29267.1| 405|Homo sapiens hydroxysteroid (11-beta... 41 0.004
BC064536-1|AAH64536.1| 405|Homo sapiens hydroxysteroid (11-beta... 41 0.004
BC036780-1|AAH36780.1| 405|Homo sapiens hydroxysteroid (11-beta... 41 0.004
BC009881-1|AAH09881.1| 260|Homo sapiens retinol dehydrogenase 1... 41 0.005
BC019317-1|AAH19317.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 40 0.007
BC011964-1|AAH11964.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 40 0.007
BC005844-1|AAH05844.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 40 0.007
AK024022-1|BAB14782.1| 219|Homo sapiens protein ( Homo sapiens ... 40 0.007
M93107-1|AAA58352.1| 343|Homo sapiens (R)-3-hydroxybutyrate deh... 40 0.009
M29037-1|AAB17014.1| 214|Homo sapiens 17 beta-hydroxysteroid de... 40 0.012
BC067131-1|AAH67131.1| 341|Homo sapiens retinol dehydrogenase 1... 40 0.012
AY358270-1|AAQ88637.1| 341|Homo sapiens RDH10 protein. 40 0.012
AF456765-1|AAN64747.1| 341|Homo sapiens retinol dehydrogenase 1... 40 0.012
EF462915-1|ABO43035.1| 277|Homo sapiens carbonyl reductase 3 pr... 39 0.016
CR541709-1|CAG46510.1| 277|Homo sapiens CBR3 protein. 39 0.016
BC002812-1|AAH02812.1| 277|Homo sapiens carbonyl reductase 3 pr... 39 0.016
BC002730-1|AAH02730.1| 302|Homo sapiens dehydrogenase/reductase... 39 0.016
AP001725-1|BAA95547.1| 277|Homo sapiens carbonyl reductase (NAD... 39 0.016
AP000689-1|BAA89425.1| 277|Homo sapiens carbonyl reductase 3 pr... 39 0.016
AL645761-2|CAI15000.1| 147|Homo sapiens dehydrogenase/reductase... 39 0.016
AL645761-1|CAI14999.1| 302|Homo sapiens dehydrogenase/reductase... 39 0.016
AL513016-1|CAH74172.1| 302|Homo sapiens dehydrogenase/reductase... 39 0.016
AK223429-1|BAD97149.1| 277|Homo sapiens carbonyl reductase 3 va... 39 0.016
AK222593-1|BAD96313.1| 302|Homo sapiens dehydrogenase/reductase... 39 0.016
AF179237-1|AAD55402.1| 302|Homo sapiens short-chain dehydrogena... 39 0.016
AF061741-1|AAC63263.1| 302|Homo sapiens retinal short-chain deh... 39 0.016
AB124847-1|BAE45939.1| 277|Homo sapiens carbonyl reductase 3 pr... 39 0.016
AB041012-1|BAD74062.1| 277|Homo sapiens NADPH-dependent carbony... 39 0.016
AB004854-1|BAA33500.1| 277|Homo sapiens carbonyl reductase 3 pr... 39 0.016
AB003151-2|BAA34207.1| 277|Homo sapiens carbonyl reductase 3 pr... 39 0.016
M76665-1|AAC31757.1| 292|Homo sapiens 11-beta-hydroxysteroid de... 39 0.021
BC012593-1|AAH12593.1| 292|Homo sapiens hydroxysteroid (11-beta... 39 0.021
AY044084-1|AAK83653.1| 292|Homo sapiens 11-beta hydroxysteroid ... 39 0.021
AL031316-4|CAI20063.1| 292|Homo sapiens hydroxysteroid (11-beta... 39 0.021
AL022398-8|CAA18541.2| 292|Homo sapiens hydroxysteroid (11-beta... 39 0.021
M76231-1|AAA60314.1| 261|Homo sapiens sepiapterin reductase pro... 38 0.028
BC017310-1|AAH17310.1| 261|Homo sapiens sepiapterin reductase (... 38 0.028
AK222942-1|BAD96662.1| 261|Homo sapiens sepiapterin reductase (... 38 0.028
M62420-1|AAA17881.1| 277|Homo sapiens carbonyl reductase protein. 38 0.036
J04056-1|AAA52070.1| 277|Homo sapiens carbonyl reductase protein. 38 0.036
EF141836-1|ABK97430.1| 277|Homo sapiens carbonyl reductase 1 pr... 38 0.036
CR541708-1|CAG46509.1| 277|Homo sapiens CBR1 protein. 38 0.036
BT019843-1|AAV38646.1| 277|Homo sapiens carbonyl reductase 1 pr... 38 0.036
BC015640-1|AAH15640.1| 277|Homo sapiens carbonyl reductase 1 pr... 38 0.036
BC002511-1|AAH02511.1| 277|Homo sapiens carbonyl reductase 1 pr... 38 0.036
AP001724-1|BAA95508.1| 277|Homo sapiens carbonyl reductase (NAP... 38 0.036
AP000688-1|BAA89424.1| 277|Homo sapiens carbonyl reductase 1 pr... 38 0.036
AB124848-1|BAE45940.1| 277|Homo sapiens carbonyl reductase 1 pr... 38 0.036
AB003151-1|BAA33498.1| 277|Homo sapiens carbonyl reductase prot... 38 0.036
AC092630-1|AAY15035.1| 198|Homo sapiens unknown protein. 38 0.048
AB017547-1|BAA34534.1| 198|Homo sapiens sepiapterin reductase p... 38 0.048
AY313894-1|AAP83166.1| 315|Homo sapiens short-chain dehydrogena... 36 0.15
AY268352-1|AAP42286.1| 286|Homo sapiens short-chain dehydrogena... 36 0.15
U63296-1|AAB53034.1| 143|Homo sapiens 15-hydroxyprostaglandin d... 33 0.78
AF069291-3|AAC62233.1| 188|Homo sapiens 2,4-dienoyl-CoA reducta... 33 1.0
U29344-1|AAA73576.1| 2509|Homo sapiens fatty acid synthase protein. 30 7.3
U26644-1|AAC50259.1| 2504|Homo sapiens fas protein. 30 7.3
BC063242-1|AAH63242.1| 2511|Homo sapiens fatty acid synthase pro... 30 7.3
BC014631-1|AAH14631.1| 774|Homo sapiens FASN protein protein. 30 7.3
AY451392-1|AAS09886.1| 2511|Homo sapiens fatty acid synthase pro... 30 7.3
AB209988-1|BAE06070.1| 2548|Homo sapiens FASN variant protein pr... 30 7.3
>BT006881-1|AAP35527.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 243 bits (595), Expect = 4e-64
Identities = 115/227 (50%), Positives = 161/227 (70%)
Frame = +1
Query: 43 MEISFKGKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVD 222
ME+ G+ +LVT L GA +VA+SRT++ L+SL E P I+ V VD
Sbjct: 1 MELFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEPVCVD 60
Query: 223 IGDWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVAR 402
+GDWE T + + S+G D LVNNAAVA+ +PFL+ + FD++F+VN++AV+ +SQ+VAR
Sbjct: 61 LGDWEATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVAR 120
Query: 403 KMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPT 582
+I GAIVN+SSQ S+ A+ +H++Y ++K ALD LT+ MALELGP+ IRVNA+NPT
Sbjct: 121 GLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPT 180
Query: 583 VIMTEMAKVGWSDPIKANEMLSKIPLGRFGEISEVXNAVVFLLSERS 723
V+MT M + WSDP KA ML++IPLG+F E+ V NA++FLLS+RS
Sbjct: 181 VVMTSMGQATWSDPHKAKTMLNRIPLGKFAEVEHVVNAILFLLSDRS 227
>BC001470-1|AAH01470.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 243 bits (595), Expect = 4e-64
Identities = 115/227 (50%), Positives = 161/227 (70%)
Frame = +1
Query: 43 MEISFKGKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVD 222
ME+ G+ +LVT L GA +VA+SRT++ L+SL E P I+ V VD
Sbjct: 1 MELFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEPVCVD 60
Query: 223 IGDWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVAR 402
+GDWE T + + S+G D LVNNAAVA+ +PFL+ + FD++F+VN++AV+ +SQ+VAR
Sbjct: 61 LGDWEATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVAR 120
Query: 403 KMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPT 582
+I GAIVN+SSQ S+ A+ +H++Y ++K ALD LT+ MALELGP+ IRVNA+NPT
Sbjct: 121 GLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPT 180
Query: 583 VIMTEMAKVGWSDPIKANEMLSKIPLGRFGEISEVXNAVVFLLSERS 723
V+MT M + WSDP KA ML++IPLG+F E+ V NA++FLLS+RS
Sbjct: 181 VVMTSMGQATWSDPHKAKTMLNRIPLGKFAEVEHVVNAILFLLSDRS 227
>AF515625-1|AAM54026.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 243 bits (595), Expect = 4e-64
Identities = 115/227 (50%), Positives = 161/227 (70%)
Frame = +1
Query: 43 MEISFKGKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVD 222
ME+ G+ +LVT L GA +VA+SRT++ L+SL E P I+ V VD
Sbjct: 1 MELFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEPVCVD 60
Query: 223 IGDWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVAR 402
+GDWE T + + S+G D LVNNAAVA+ +PFL+ + FD++F+VN++AV+ +SQ+VAR
Sbjct: 61 LGDWEATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVAR 120
Query: 403 KMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPT 582
+I GAIVN+SSQ S+ A+ +H++Y ++K ALD LT+ MALELGP+ IRVNA+NPT
Sbjct: 121 GLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPT 180
Query: 583 VIMTEMAKVGWSDPIKANEMLSKIPLGRFGEISEVXNAVVFLLSERS 723
V+MT M + WSDP KA ML++IPLG+F E+ V NA++FLLS+RS
Sbjct: 181 VVMTSMGQATWSDPHKAKTMLNRIPLGKFAEVEHVVNAILFLLSDRS 227
>AF515624-1|AAO15991.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 243 bits (595), Expect = 4e-64
Identities = 115/227 (50%), Positives = 161/227 (70%)
Frame = +1
Query: 43 MEISFKGKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVD 222
ME+ G+ +LVT L GA +VA+SRT++ L+SL E P I+ V VD
Sbjct: 1 MELFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEPVCVD 60
Query: 223 IGDWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVAR 402
+GDWE T + + S+G D LVNNAAVA+ +PFL+ + FD++F+VN++AV+ +SQ+VAR
Sbjct: 61 LGDWEATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVAR 120
Query: 403 KMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPT 582
+I GAIVN+SSQ S+ A+ +H++Y ++K ALD LT+ MALELGP+ IRVNA+NPT
Sbjct: 121 GLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPT 180
Query: 583 VIMTEMAKVGWSDPIKANEMLSKIPLGRFGEISEVXNAVVFLLSERS 723
V+MT M + WSDP KA ML++IPLG+F E+ V NA++FLLS+RS
Sbjct: 181 VVMTSMGQATWSDPHKAKTMLNRIPLGKFAEVEHVVNAILFLLSDRS 227
>AF515623-1|AAN59786.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 243 bits (595), Expect = 4e-64
Identities = 115/227 (50%), Positives = 161/227 (70%)
Frame = +1
Query: 43 MEISFKGKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVD 222
ME+ G+ +LVT L GA +VA+SRT++ L+SL E P I+ V VD
Sbjct: 1 MELFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEPVCVD 60
Query: 223 IGDWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVAR 402
+GDWE T + + S+G D LVNNAAVA+ +PFL+ + FD++F+VN++AV+ +SQ+VAR
Sbjct: 61 LGDWEATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVAR 120
Query: 403 KMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPT 582
+I GAIVN+SSQ S+ A+ +H++Y ++K ALD LT+ MALELGP+ IRVNA+NPT
Sbjct: 121 GLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPT 180
Query: 583 VIMTEMAKVGWSDPIKANEMLSKIPLGRFGEISEVXNAVVFLLSERS 723
V+MT M + WSDP KA ML++IPLG+F E+ V NA++FLLS+RS
Sbjct: 181 VVMTSMGQATWSDPHKAKTMLNRIPLGKFAEVEHVVNAILFLLSDRS 227
>AF113123-1|AAF14864.1| 244|Homo sapiens carbonyl reductase
protein.
Length = 244
Score = 243 bits (595), Expect = 4e-64
Identities = 115/227 (50%), Positives = 161/227 (70%)
Frame = +1
Query: 43 MEISFKGKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVD 222
ME+ G+ +LVT L GA +VA+SRT++ L+SL E P I+ V VD
Sbjct: 1 MELFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEPVCVD 60
Query: 223 IGDWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVAR 402
+GDWE T + + S+G D LVNNAAVA+ +PFL+ + FD++F+VN++AV+ +SQ+VAR
Sbjct: 61 LGDWEATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVAR 120
Query: 403 KMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPT 582
+I GAIVN+SSQ S+ A+ +H++Y ++K ALD LT+ MALELGP+ IRVNA+NPT
Sbjct: 121 GLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPT 180
Query: 583 VIMTEMAKVGWSDPIKANEMLSKIPLGRFGEISEVXNAVVFLLSERS 723
V+MT M + WSDP KA ML++IPLG+F E+ V NA++FLLS+RS
Sbjct: 181 VVMTSMGQATWSDPHKAKTMLNRIPLGKFAEVEHVVNAILFLLSDRS 227
>AB013846-1|BAB64299.1| 244|Homo sapiens kidney dicarbonyl
reductase protein.
Length = 244
Score = 243 bits (595), Expect = 4e-64
Identities = 115/227 (50%), Positives = 161/227 (70%)
Frame = +1
Query: 43 MEISFKGKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVD 222
ME+ G+ +LVT L GA +VA+SRT++ L+SL E P I+ V VD
Sbjct: 1 MELFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEPVCVD 60
Query: 223 IGDWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVAR 402
+GDWE T + + S+G D LVNNAAVA+ +PFL+ + FD++F+VN++AV+ +SQ+VAR
Sbjct: 61 LGDWEATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVAR 120
Query: 403 KMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPT 582
+I GAIVN+SSQ S+ A+ +H++Y ++K ALD LT+ MALELGP+ IRVNA+NPT
Sbjct: 121 GLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPT 180
Query: 583 VIMTEMAKVGWSDPIKANEMLSKIPLGRFGEISEVXNAVVFLLSERS 723
V+MT M + WSDP KA ML++IPLG+F E+ V NA++FLLS+RS
Sbjct: 181 VVMTSMGQATWSDPHKAKTMLNRIPLGKFAEVEHVVNAILFLLSDRS 227
>AF139841-1|AAP97273.1| 244|Homo sapiens carbonyl reductase II
protein.
Length = 244
Score = 241 bits (591), Expect = 1e-63
Identities = 114/227 (50%), Positives = 160/227 (70%)
Frame = +1
Query: 43 MEISFKGKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVD 222
ME+ G+ +LVT L GA +VA+SRT++ L+SL E P I+ V VD
Sbjct: 1 MELFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEPVCVD 60
Query: 223 IGDWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVAR 402
+GDWE T + + S+G D LVNNAAVA+ +PFL+ + FD++F+VN++AV+ +SQ+ AR
Sbjct: 61 LGDWEATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIAAR 120
Query: 403 KMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPT 582
+I GAIVN+SSQ S+ A+ +H++Y ++K ALD LT+ MALELGP+ IRVNA+NPT
Sbjct: 121 GLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPT 180
Query: 583 VIMTEMAKVGWSDPIKANEMLSKIPLGRFGEISEVXNAVVFLLSERS 723
V+MT M + WSDP KA ML++IPLG+F E+ V NA++FLLS+RS
Sbjct: 181 VVMTSMGQATWSDPHKAKTMLNRIPLGKFAEVEHVVNAILFLLSDRS 227
>BC003018-1|AAH03018.1| 243|Homo sapiens Unknown (protein for
IMAGE:2822726) protein.
Length = 243
Score = 241 bits (590), Expect = 2e-63
Identities = 114/226 (50%), Positives = 160/226 (70%)
Frame = +1
Query: 46 EISFKGKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDI 225
E+ G+ +LVT L GA +VA+SRT++ L+SL E P I+ V VD+
Sbjct: 1 ELFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEPVCVDL 60
Query: 226 GDWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARK 405
GDWE T + + S+G D LVNNAAVA+ +PFL+ + FD++F+VN++AV+ +SQ+VAR
Sbjct: 61 GDWEATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARG 120
Query: 406 MIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTV 585
+I GAIVN+SSQ S+ A+ +H++Y ++K ALD LT+ MALELGP+ IRVNA+NPTV
Sbjct: 121 LIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTV 180
Query: 586 IMTEMAKVGWSDPIKANEMLSKIPLGRFGEISEVXNAVVFLLSERS 723
+MT M + WSDP KA ML++IPLG+F E+ V NA++FLLS+RS
Sbjct: 181 VMTSMGQATWSDPHKAKTMLNRIPLGKFAEVEHVVNAILFLLSDRS 226
>DQ344810-1|ABD75823.1| 278|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase short isoform protein.
Length = 278
Score = 100 bits (240), Expect = 5e-21
Identities = 72/227 (31%), Positives = 113/227 (49%), Gaps = 9/227 (3%)
Frame = +1
Query: 64 KXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLE----SLQSEYPSIDIVDVDIGD 231
K LVT L + GA++V SR + +++ +LQ E S+ +G
Sbjct: 33 KVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGK 92
Query: 232 WEKTRKVVESL----GHFDALVNNAAV-AVCEPFLDCSPSNFDKTFDVNVKAVLNISQVV 396
E ++V + G D LV+NAAV +D + +DKT D+NVKA +++ V
Sbjct: 93 AEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTKAV 152
Query: 397 ARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAIN 576
+M E + G++V +SS A+ + + Y+ SK AL LT+ +A+EL P IRVN +
Sbjct: 153 VPEM-EKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLA 211
Query: 577 PTVIMTEMAKVGWSDPIKANEMLSKIPLGRFGEISEVXNAVVFLLSE 717
P +I T +++ W D K M + + R GE + V FL SE
Sbjct: 212 PGLIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSE 258
>BC003019-1|AAH03019.1| 278|Homo sapiens dehydrogenase/reductase
(SDR family) member 4 protein.
Length = 278
Score = 100 bits (240), Expect = 5e-21
Identities = 72/227 (31%), Positives = 113/227 (49%), Gaps = 9/227 (3%)
Frame = +1
Query: 64 KXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLE----SLQSEYPSIDIVDVDIGD 231
K LVT L + GA++V SR + +++ +LQ E S+ +G
Sbjct: 33 KVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGK 92
Query: 232 WEKTRKVVESL----GHFDALVNNAAV-AVCEPFLDCSPSNFDKTFDVNVKAVLNISQVV 396
E ++V + G D LV+NAAV +D + +DKT D+NVKA +++ V
Sbjct: 93 AEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTKAV 152
Query: 397 ARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAIN 576
+M E + G++V +SS A+ + + Y+ SK AL LT+ +A+EL P IRVN +
Sbjct: 153 VPEM-EKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLA 211
Query: 577 PTVIMTEMAKVGWSDPIKANEMLSKIPLGRFGEISEVXNAVVFLLSE 717
P +I T +++ W D K M + + R GE + V FL SE
Sbjct: 212 PGLIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSE 258
>AY358638-1|AAQ89001.1| 278|Homo sapiens SCAD-SRL protein.
Length = 278
Score = 100 bits (240), Expect = 5e-21
Identities = 72/227 (31%), Positives = 113/227 (49%), Gaps = 9/227 (3%)
Frame = +1
Query: 64 KXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLE----SLQSEYPSIDIVDVDIGD 231
K LVT L + GA++V SR + +++ +LQ E S+ +G
Sbjct: 33 KVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGK 92
Query: 232 WEKTRKVVESL----GHFDALVNNAAV-AVCEPFLDCSPSNFDKTFDVNVKAVLNISQVV 396
E ++V + G D LV+NAAV +D + +DKT D+NVKA +++ V
Sbjct: 93 AEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTKAV 152
Query: 397 ARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAIN 576
+M E + G++V +SS A+ + + Y+ SK AL LT+ +A+EL P IRVN +
Sbjct: 153 VPEM-EKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLA 211
Query: 577 PTVIMTEMAKVGWSDPIKANEMLSKIPLGRFGEISEVXNAVVFLLSE 717
P +I T +++ W D K M + + R GE + V FL SE
Sbjct: 212 PGLIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSE 258
>AB045131-1|BAB18775.1| 260|Homo sapiens NADPH-dependent retinol
dehydrogenase/reductase protein.
Length = 260
Score = 100 bits (240), Expect = 5e-21
Identities = 72/227 (31%), Positives = 113/227 (49%), Gaps = 9/227 (3%)
Frame = +1
Query: 64 KXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLE----SLQSEYPSIDIVDVDIGD 231
K LVT L + GA++V SR + +++ +LQ E S+ +G
Sbjct: 15 KVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGK 74
Query: 232 WEKTRKVVESL----GHFDALVNNAAV-AVCEPFLDCSPSNFDKTFDVNVKAVLNISQVV 396
E ++V + G D LV+NAAV +D + +DKT D+NVKA +++ V
Sbjct: 75 AEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTKAV 134
Query: 397 ARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAIN 576
+M E + G++V +SS A+ + + Y+ SK AL LT+ +A+EL P IRVN +
Sbjct: 135 VPEM-EKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLA 193
Query: 577 PTVIMTEMAKVGWSDPIKANEMLSKIPLGRFGEISEVXNAVVFLLSE 717
P +I T +++ W D K M + + R GE + V FL SE
Sbjct: 194 PGLIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSE 240
>AF064256-1|AAQ13444.1| 278|Homo sapiens Hep27-like protein
protein.
Length = 278
Score = 99 bits (238), Expect = 8e-21
Identities = 72/227 (31%), Positives = 113/227 (49%), Gaps = 9/227 (3%)
Frame = +1
Query: 64 KXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLE----SLQSEYPSIDIVDVDIGD 231
K LVT L + GA++V SR + +++ +LQ E S+ +G
Sbjct: 33 KVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCMVGK 92
Query: 232 WEKTRKVVESL----GHFDALVNNAAV-AVCEPFLDCSPSNFDKTFDVNVKAVLNISQVV 396
E ++V + G D LV+NAAV +D + +DKT D+NVKA +++ V
Sbjct: 93 AEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTKAV 152
Query: 397 ARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAIN 576
+M E + G++V +SS A+ + + Y+ SK AL LT+ +A+EL P IRVN +
Sbjct: 153 VPEM-EKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLA 211
Query: 577 PTVIMTEMAKVGWSDPIKANEMLSKIPLGRFGEISEVXNAVVFLLSE 717
P +I T +++ W D K M + + R GE + V FL SE
Sbjct: 212 PGLIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSE 258
>AF044127-1|AAD02292.1| 260|Homo sapiens peroxisomal short-chain
alcohol dehydrogenase protein.
Length = 260
Score = 99 bits (238), Expect = 8e-21
Identities = 72/227 (31%), Positives = 112/227 (49%), Gaps = 9/227 (3%)
Frame = +1
Query: 64 KXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLE----SLQSEYPSIDIVDVDIGD 231
K LVT L + GA++V SR + +++ +LQ E S+ +G
Sbjct: 15 KVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGK 74
Query: 232 WEKTRKVVESL----GHFDALVNNAAV-AVCEPFLDCSPSNFDKTFDVNVKAVLNISQVV 396
E ++V G D LV+NAAV +D + +DKT D+NVKA +++ V
Sbjct: 75 AEDRERLVAMAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVKAPALMTKAV 134
Query: 397 ARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAIN 576
+M E + G++V +SS A+ + + Y+ SK AL LT+ +A+EL P IRVN +
Sbjct: 135 VPEM-EKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLA 193
Query: 577 PTVIMTEMAKVGWSDPIKANEMLSKIPLGRFGEISEVXNAVVFLLSE 717
P +I T +++ W D K M + + R GE + V FL SE
Sbjct: 194 PGLIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSE 240
>AK001870-1|BAA91953.1| 278|Homo sapiens protein ( Homo sapiens
cDNA FLJ11008 fis, clone PLACE1003100, moderately
similar to HEP27 PROTEIN. ).
Length = 278
Score = 99.1 bits (236), Expect = 1e-20
Identities = 71/227 (31%), Positives = 112/227 (49%), Gaps = 9/227 (3%)
Frame = +1
Query: 64 KXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLE----SLQSEYPSIDIVDVDIGD 231
K L T L + GA++V SR + +++ +LQ E S+ +G
Sbjct: 33 KVALATASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGK 92
Query: 232 WEKTRKVVESL----GHFDALVNNAAV-AVCEPFLDCSPSNFDKTFDVNVKAVLNISQVV 396
E ++V + G D LV+NAAV +D + +DKT D+NVKA +++ V
Sbjct: 93 AEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTKAV 152
Query: 397 ARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAIN 576
+M E + G++V +SS A+ + + Y+ SK AL LT+ +A+EL P IRVN +
Sbjct: 153 VPEM-EKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLA 211
Query: 577 PTVIMTEMAKVGWSDPIKANEMLSKIPLGRFGEISEVXNAVVFLLSE 717
P +I T +++ W D K M + + R GE + V FL SE
Sbjct: 212 PGLIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSE 258
>BT007239-1|AAP35903.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 89.4 bits (212), Expect = 1e-17
Identities = 56/149 (37%), Positives = 79/149 (53%), Gaps = 1/149 (0%)
Frame = +1
Query: 280 LVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQAS 459
+V+ A + E L S ++DK VN+K ++Q A+ ++ N G+I+NISS
Sbjct: 100 VVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVG 159
Query: 460 KAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMA-KVGWSDPIKAN 636
K T Y+ASKA + LT+ A ELG +GIR N++ P I T M KV K
Sbjct: 160 KVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKIT 219
Query: 637 EMLSKIPLGRFGEISEVXNAVVFLLSERS 723
EM IP+G G+ +V + V FL SE S
Sbjct: 220 EM---IPMGHLGDPEDVADVVAFLASEDS 245
>BC008185-1|AAH08185.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 89.4 bits (212), Expect = 1e-17
Identities = 56/149 (37%), Positives = 79/149 (53%), Gaps = 1/149 (0%)
Frame = +1
Query: 280 LVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQAS 459
+V+ A + E L S ++DK VN+K ++Q A+ ++ N G+I+NISS
Sbjct: 100 VVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVG 159
Query: 460 KAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMA-KVGWSDPIKAN 636
K T Y+ASKA + LT+ A ELG +GIR N++ P I T M KV K
Sbjct: 160 KVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKIT 219
Query: 637 EMLSKIPLGRFGEISEVXNAVVFLLSERS 723
EM IP+G G+ +V + V FL SE S
Sbjct: 220 EM---IPMGHLGDPEDVADVVAFLASEDS 245
>AL844527-12|CAI41840.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 89.4 bits (212), Expect = 1e-17
Identities = 56/149 (37%), Positives = 79/149 (53%), Gaps = 1/149 (0%)
Frame = +1
Query: 280 LVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQAS 459
+V+ A + E L S ++DK VN+K ++Q A+ ++ N G+I+NISS
Sbjct: 100 VVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVG 159
Query: 460 KAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMA-KVGWSDPIKAN 636
K T Y+ASKA + LT+ A ELG +GIR N++ P I T M KV K
Sbjct: 160 KVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKIT 219
Query: 637 EMLSKIPLGRFGEISEVXNAVVFLLSERS 723
EM IP+G G+ +V + V FL SE S
Sbjct: 220 EM---IPMGHLGDPEDVADVVAFLASEDS 245
>AL713971-6|CAI17657.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 89.4 bits (212), Expect = 1e-17
Identities = 56/149 (37%), Positives = 79/149 (53%), Gaps = 1/149 (0%)
Frame = +1
Query: 280 LVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQAS 459
+V+ A + E L S ++DK VN+K ++Q A+ ++ N G+I+NISS
Sbjct: 100 VVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVG 159
Query: 460 KAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMA-KVGWSDPIKAN 636
K T Y+ASKA + LT+ A ELG +GIR N++ P I T M KV K
Sbjct: 160 KVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKIT 219
Query: 637 EMLSKIPLGRFGEISEVXNAVVFLLSERS 723
EM IP+G G+ +V + V FL SE S
Sbjct: 220 EM---IPMGHLGDPEDVADVVAFLASEDS 245
>AL662824-24|CAI17616.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 89.4 bits (212), Expect = 1e-17
Identities = 56/149 (37%), Positives = 79/149 (53%), Gaps = 1/149 (0%)
Frame = +1
Query: 280 LVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQAS 459
+V+ A + E L S ++DK VN+K ++Q A+ ++ N G+I+NISS
Sbjct: 100 VVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVG 159
Query: 460 KAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMA-KVGWSDPIKAN 636
K T Y+ASKA + LT+ A ELG +GIR N++ P I T M KV K
Sbjct: 160 KVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKIT 219
Query: 637 EMLSKIPLGRFGEISEVXNAVVFLLSERS 723
EM IP+G G+ +V + V FL SE S
Sbjct: 220 EM---IPMGHLGDPEDVADVVAFLASEDS 245
>AL645940-10|CAI18068.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 89.4 bits (212), Expect = 1e-17
Identities = 56/149 (37%), Positives = 79/149 (53%), Gaps = 1/149 (0%)
Frame = +1
Query: 280 LVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQAS 459
+V+ A + E L S ++DK VN+K ++Q A+ ++ N G+I+NISS
Sbjct: 100 VVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVG 159
Query: 460 KAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMA-KVGWSDPIKAN 636
K T Y+ASKA + LT+ A ELG +GIR N++ P I T M KV K
Sbjct: 160 KVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKIT 219
Query: 637 EMLSKIPLGRFGEISEVXNAVVFLLSERS 723
EM IP+G G+ +V + V FL SE S
Sbjct: 220 EM---IPMGHLGDPEDVADVVAFLASEDS 245
>AL031228-10|CAC38444.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 89.4 bits (212), Expect = 1e-17
Identities = 56/149 (37%), Positives = 79/149 (53%), Gaps = 1/149 (0%)
Frame = +1
Query: 280 LVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQAS 459
+V+ A + E L S ++DK VN+K ++Q A+ ++ N G+I+NISS
Sbjct: 100 VVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVG 159
Query: 460 KAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMA-KVGWSDPIKAN 636
K T Y+ASKA + LT+ A ELG +GIR N++ P I T M KV K
Sbjct: 160 KVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKIT 219
Query: 637 EMLSKIPLGRFGEISEVXNAVVFLLSERS 723
EM IP+G G+ +V + V FL SE S
Sbjct: 220 EM---IPMGHLGDPEDVADVVAFLASEDS 245
>AY358841-1|AAQ89200.1| 245|Homo sapiens GRLD6308 protein.
Length = 245
Score = 87.4 bits (207), Expect = 5e-17
Identities = 60/226 (26%), Positives = 105/226 (46%), Gaps = 5/226 (2%)
Frame = +1
Query: 61 GKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDIGDWEK 240
GK I++T R GA ++A S L+ L+ +YP I +D+ ++
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELE-KYPGIQTRVLDVTKKKQ 64
Query: 241 TRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENK 420
+ + D L N A LDC ++D + ++NV+++ + + KM+ K
Sbjct: 65 IDQFASEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQK 124
Query: 421 THGAIVNISSQASKA-ALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMT- 594
+ G I+N+SS AS + + +YS +KAA+ LT+++A + GIR N + P + T
Sbjct: 125 S-GNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSLAADFIQQGIRCNCVCPGTVDTP 183
Query: 595 ---EMAKVGWSDPIKANEMLSKIPLGRFGEISEVXNAVVFLLSERS 723
E + + N+ L + GRF E+ V+L S+ S
Sbjct: 184 SLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDES 229
>D82061-1|BAA11529.1| 259|Homo sapiens a member of the short-chain
alcohol dehydrogenase family protein.
Length = 259
Score = 87.0 bits (206), Expect = 6e-17
Identities = 53/149 (35%), Positives = 80/149 (53%), Gaps = 1/149 (0%)
Frame = +1
Query: 280 LVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQAS 459
+V+ A + E L S ++DK VN+K ++Q A+ ++ N G+I+NISS
Sbjct: 98 VVSCAGITQDEFLLHMSRDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVG 157
Query: 460 KAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMAKVGWSDPIKANE 639
K T Y+ASKA + LT+ A ELG +GI N++ P I T M K P K +
Sbjct: 158 KVGNVGQTNYAASKAGVIGLTQTAARELGRHGIPCNSVLPGFIATPMTK---KVPKKVVD 214
Query: 640 MLSK-IPLGRFGEISEVXNAVVFLLSERS 723
+++ IP+G G+ +V + V FL SE S
Sbjct: 215 KITEMIPMGHLGDPEDVADVVAFLASEDS 243
>BC095414-1|AAH95414.1| 245|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 2 protein.
Length = 245
Score = 87.0 bits (206), Expect = 6e-17
Identities = 60/226 (26%), Positives = 105/226 (46%), Gaps = 5/226 (2%)
Frame = +1
Query: 61 GKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDIGDWEK 240
GK I++T R GA ++A S L+ L+ +YP I +D+ ++
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELE-KYPGIQTRVLDVTKKKQ 64
Query: 241 TRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENK 420
+ + D L N A LDC ++D + ++NV+++ + + KM+ K
Sbjct: 65 IDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQK 124
Query: 421 THGAIVNISSQASKA-ALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMT- 594
+ G I+N+SS AS + + +YS +KAA+ LT+++A + GIR N + P + T
Sbjct: 125 S-GNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTP 183
Query: 595 ---EMAKVGWSDPIKANEMLSKIPLGRFGEISEVXNAVVFLLSERS 723
E + + N+ L + GRF E+ V+L S+ S
Sbjct: 184 SLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDES 229
>BC001953-1|AAH01953.1| 245|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 2 protein.
Length = 245
Score = 87.0 bits (206), Expect = 6e-17
Identities = 60/226 (26%), Positives = 105/226 (46%), Gaps = 5/226 (2%)
Frame = +1
Query: 61 GKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDIGDWEK 240
GK I++T R GA ++A S L+ L+ +YP I +D+ ++
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELE-KYPGIQTRVLDVTKKKQ 64
Query: 241 TRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENK 420
+ + D L N A LDC ++D + ++NV+++ + + KM+ K
Sbjct: 65 IDQFASEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQK 124
Query: 421 THGAIVNISSQASKA-ALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMT- 594
+ G I+N+SS AS + + +YS +KAA+ LT+++A + GIR N + P + T
Sbjct: 125 S-GNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTP 183
Query: 595 ---EMAKVGWSDPIKANEMLSKIPLGRFGEISEVXNAVVFLLSERS 723
E + + N+ L + GRF E+ V+L S+ S
Sbjct: 184 SLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDES 229
>AF164790-1|AAF80754.1| 245|Homo sapiens oxidoreductase UCPA
protein.
Length = 245
Score = 87.0 bits (206), Expect = 6e-17
Identities = 60/226 (26%), Positives = 105/226 (46%), Gaps = 5/226 (2%)
Frame = +1
Query: 61 GKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDIGDWEK 240
GK I++T R GA ++A S L+ L+ +YP I +D+ ++
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELE-KYPGIQTRVLDVTKKKQ 64
Query: 241 TRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENK 420
+ + D L N A LDC ++D + ++NV+++ + + KM+ K
Sbjct: 65 IDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQK 124
Query: 421 THGAIVNISSQASKA-ALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMT- 594
+ G I+N+SS AS + + +YS +KAA+ LT+++A + GIR N + P + T
Sbjct: 125 S-GNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTP 183
Query: 595 ---EMAKVGWSDPIKANEMLSKIPLGRFGEISEVXNAVVFLLSERS 723
E + + N+ L + GRF E+ V+L S+ S
Sbjct: 184 SLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDES 229
>AF126781-1|AAF06940.1| 270|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR3 protein.
Length = 270
Score = 85.4 bits (202), Expect = 2e-16
Identities = 65/230 (28%), Positives = 105/230 (45%), Gaps = 9/230 (3%)
Frame = +1
Query: 55 FKGKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIV--DVDIG 228
+ GK ++VT +GA +V + S +L+ E P + DV
Sbjct: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQE 66
Query: 229 DWEKT--RKVVESLGHFDALVNNAAV-AVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVA 399
D KT + + G D +VNNA + + S F + ++N+ ++++
Sbjct: 67 DDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLAL 126
Query: 400 RKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINP 579
+ K+ G ++NISS Y A+K A+ A+T+A+AL+ PYG+RVN I+P
Sbjct: 127 PYL--RKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISP 184
Query: 580 ----TVIMTEMAKVGWSDPIKANEMLSKIPLGRFGEISEVXNAVVFLLSE 717
T + E+A + E + PLGR G+ +EV A VFL SE
Sbjct: 185 GNIWTPLWEELAALMPDPRASIREGMLAQPLGRMGQPAEVGAAAVFLASE 234
>BC006294-1|AAH06294.1| 270|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 14 protein.
Length = 270
Score = 85.0 bits (201), Expect = 2e-16
Identities = 65/230 (28%), Positives = 105/230 (45%), Gaps = 9/230 (3%)
Frame = +1
Query: 55 FKGKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIV--DVDIG 228
+ GK ++VT +GA +V + S +L+ E P + DV
Sbjct: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQE 66
Query: 229 DWEKT--RKVVESLGHFDALVNNAAV-AVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVA 399
D KT + + G D +VNNA + + S F + ++N+ ++++
Sbjct: 67 DDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLAL 126
Query: 400 RKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINP 579
+ K+ G ++NISS Y A+K A+ A+T+A+AL+ PYG+RVN I+P
Sbjct: 127 PYL--RKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISP 184
Query: 580 ----TVIMTEMAKVGWSDPIKANEMLSKIPLGRFGEISEVXNAVVFLLSE 717
T + E+A + E + PLGR G+ +EV A VFL SE
Sbjct: 185 GNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE 234
>BC006283-1|AAH06283.1| 270|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 14 protein.
Length = 270
Score = 85.0 bits (201), Expect = 2e-16
Identities = 65/230 (28%), Positives = 105/230 (45%), Gaps = 9/230 (3%)
Frame = +1
Query: 55 FKGKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIV--DVDIG 228
+ GK ++VT +GA +V + S +L+ E P + DV
Sbjct: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQE 66
Query: 229 DWEKT--RKVVESLGHFDALVNNAAV-AVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVA 399
D KT + + G D +VNNA + + S F + ++N+ ++++
Sbjct: 67 DDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLAL 126
Query: 400 RKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINP 579
+ K+ G ++NISS Y A+K A+ A+T+A+AL+ PYG+RVN I+P
Sbjct: 127 PYL--RKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISP 184
Query: 580 ----TVIMTEMAKVGWSDPIKANEMLSKIPLGRFGEISEVXNAVVFLLSE 717
T + E+A + E + PLGR G+ +EV A VFL SE
Sbjct: 185 GNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE 234
>AY358430-1|AAQ88796.1| 270|Homo sapiens ATGT502 protein.
Length = 270
Score = 85.0 bits (201), Expect = 2e-16
Identities = 65/230 (28%), Positives = 105/230 (45%), Gaps = 9/230 (3%)
Frame = +1
Query: 55 FKGKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIV--DVDIG 228
+ GK ++VT +GA +V + S +L+ E P + DV
Sbjct: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQE 66
Query: 229 DWEKT--RKVVESLGHFDALVNNAAV-AVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVA 399
D KT + + G D +VNNA + + S F + ++N+ ++++
Sbjct: 67 DDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLAL 126
Query: 400 RKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINP 579
+ K+ G ++NISS Y A+K A+ A+T+A+AL+ PYG+RVN I+P
Sbjct: 127 PYL--RKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISP 184
Query: 580 ----TVIMTEMAKVGWSDPIKANEMLSKIPLGRFGEISEVXNAVVFLLSE 717
T + E+A + E + PLGR G+ +EV A VFL SE
Sbjct: 185 GNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE 234
>U78302-1|AAB88724.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 80.6 bits (190), Expect = 5e-15
Identities = 59/233 (25%), Positives = 107/233 (45%), Gaps = 11/233 (4%)
Frame = +1
Query: 52 SFKGKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPS-----IDIVD 216
SF+GK +T L GA V SR L++ + S + +
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQ 115
Query: 217 VDIGDWEKTRKVVESL----GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNI 384
D+ D + + V L GH + ++NNAA P SP+ + D+ + +
Sbjct: 116 CDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAFV 175
Query: 385 SQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRV 564
+ + +++I+ + A ++I++ ++ +++KA ++A+++++A E G YG+R
Sbjct: 176 TLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRF 235
Query: 565 NAINPTVIMTEMAKVGWSDPIKA--NEMLSKIPLGRFGEISEVXNAVVFLLSE 717
N I P I T+ A DP EM+ +IP GR G + E+ N FL S+
Sbjct: 236 NVIQPGPIKTKGA-FSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFLCSD 287
>L26050-1|AAA67551.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 80.6 bits (190), Expect = 5e-15
Identities = 59/233 (25%), Positives = 107/233 (45%), Gaps = 11/233 (4%)
Frame = +1
Query: 52 SFKGKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPS-----IDIVD 216
SF+GK +T L GA V SR L++ + S + +
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQ 115
Query: 217 VDIGDWEKTRKVVESL----GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNI 384
D+ D + + V L GH + ++NNAA P SP+ + D+ + +
Sbjct: 116 CDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAFV 175
Query: 385 SQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRV 564
+ + +++I+ + A ++I++ ++ +++KA ++A+++++A E G YG+R
Sbjct: 176 TLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRF 235
Query: 565 NAINPTVIMTEMAKVGWSDPIKA--NEMLSKIPLGRFGEISEVXNAVVFLLSE 717
N I P I T+ A DP EM+ +IP GR G + E+ N FL S+
Sbjct: 236 NVIQPGPIKTKGA-FSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFLCSD 287
>BC105082-1|AAI05083.1| 335|Homo sapiens 2,4-dienoyl CoA reductase
1, mitochondrial protein.
Length = 335
Score = 80.6 bits (190), Expect = 5e-15
Identities = 59/233 (25%), Positives = 107/233 (45%), Gaps = 11/233 (4%)
Frame = +1
Query: 52 SFKGKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPS-----IDIVD 216
SF+GK +T L GA V SR L++ + S + +
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQ 115
Query: 217 VDIGDWEKTRKVVESL----GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNI 384
D+ D + + V L GH + ++NNAA P SP+ + D+ + +
Sbjct: 116 CDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAFV 175
Query: 385 SQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRV 564
+ + +++I+ + A ++I++ ++ +++KA ++A+++++A E G YG+R
Sbjct: 176 TLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRF 235
Query: 565 NAINPTVIMTEMAKVGWSDPIKA--NEMLSKIPLGRFGEISEVXNAVVFLLSE 717
N I P I T+ A DP EM+ +IP GR G + E+ N FL S+
Sbjct: 236 NVIQPGPIKTKGA-FSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFLCSD 287
>BC105080-1|AAI05081.1| 335|Homo sapiens 2,4-dienoyl CoA reductase
1, mitochondrial protein.
Length = 335
Score = 80.6 bits (190), Expect = 5e-15
Identities = 59/233 (25%), Positives = 107/233 (45%), Gaps = 11/233 (4%)
Frame = +1
Query: 52 SFKGKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPS-----IDIVD 216
SF+GK +T L GA V SR L++ + S + +
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQ 115
Query: 217 VDIGDWEKTRKVVESL----GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNI 384
D+ D + + V L GH + ++NNAA P SP+ + D+ + +
Sbjct: 116 CDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAFV 175
Query: 385 SQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRV 564
+ + +++I+ + A ++I++ ++ +++KA ++A+++++A E G YG+R
Sbjct: 176 TLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRF 235
Query: 565 NAINPTVIMTEMAKVGWSDPIKA--NEMLSKIPLGRFGEISEVXNAVVFLLSE 717
N I P I T+ A DP EM+ +IP GR G + E+ N FL S+
Sbjct: 236 NVIQPGPIKTKGA-FSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFLCSD 287
>AC004612-1|AAC14671.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
precursor protein.
Length = 335
Score = 80.6 bits (190), Expect = 5e-15
Identities = 59/233 (25%), Positives = 107/233 (45%), Gaps = 11/233 (4%)
Frame = +1
Query: 52 SFKGKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPS-----IDIVD 216
SF+GK +T L GA V SR L++ + S + +
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQ 115
Query: 217 VDIGDWEKTRKVVESL----GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNI 384
D+ D + + V L GH + ++NNAA P SP+ + D+ + +
Sbjct: 116 CDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAFV 175
Query: 385 SQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRV 564
+ + +++I+ + A ++I++ ++ +++KA ++A+++++A E G YG+R
Sbjct: 176 TLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRF 235
Query: 565 NAINPTVIMTEMAKVGWSDPIKA--NEMLSKIPLGRFGEISEVXNAVVFLLSE 717
N I P I T+ A DP EM+ +IP GR G + E+ N FL S+
Sbjct: 236 NVIQPGPIKTKGA-FSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFLCSD 287
>U49352-1|AAB09423.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 79.8 bits (188), Expect = 9e-15
Identities = 59/232 (25%), Positives = 106/232 (45%), Gaps = 11/232 (4%)
Frame = +1
Query: 52 SFKGKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPS-----IDIVD 216
SF+GK +T L GA V SR L++ + S + +
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQ 115
Query: 217 VDIGDWEKTRKVVESL----GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNI 384
D+ D + + V L GH + ++NNAA P SP+ + D+ + +
Sbjct: 116 CDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAFV 175
Query: 385 SQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRV 564
+ + +++I+ + A ++I++ ++ +++KA ++A+++++A E G YG+R
Sbjct: 176 TLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRF 235
Query: 565 NAINPTVIMTEMAKVGWSDPIKA--NEMLSKIPLGRFGEISEVXNAVVFLLS 714
N I P I T+ A DP EM+ +IP GR G + E+ N FL S
Sbjct: 236 NVIQPGPIKTKGA-FSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFLCS 286
>U31875-1|AAA82048.1| 280|Homo sapiens Hep27 protein protein.
Length = 280
Score = 79.0 bits (186), Expect = 2e-14
Identities = 71/224 (31%), Positives = 106/224 (47%), Gaps = 10/224 (4%)
Frame = +1
Query: 73 LVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLE----SLQSEYPSIDIVDVDIGDWEK 240
+VT L R GA++V SR + +++ LQ E S+ + +G E
Sbjct: 40 VVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVGKAED 99
Query: 241 TRKVV----ESLGHFDALVNNAAV-AVCEPFLDCSPSNFDKTFDVNVKA-VLNISQVVAR 402
++V E G D LV +A V + L S +DK VNVK+ L +SQ++
Sbjct: 100 REQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLLSQLLP- 158
Query: 403 KMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPT 582
+EN+ GA++ +SS A+ + +Y+ SK AL LTR +ALEL P IRVN + P
Sbjct: 159 -YMENR-RGAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIRVNCVVPG 216
Query: 583 VIMTEMAKVGWSDPIKANEMLSKIPLGRFGEISEVXNAVVFLLS 714
+I T+ +KV + L R GE + V FL S
Sbjct: 217 IIKTDFSKVFHGNESLWKNFKEHHQLQRIGESEDCAGIVSFLCS 260
>BC007339-1|AAH07339.2| 271|Homo sapiens DHRS2 protein protein.
Length = 271
Score = 79.0 bits (186), Expect = 2e-14
Identities = 71/224 (31%), Positives = 106/224 (47%), Gaps = 10/224 (4%)
Frame = +1
Query: 73 LVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLE----SLQSEYPSIDIVDVDIGDWEK 240
+VT L R GA++V SR + +++ LQ E S+ + +G E
Sbjct: 31 VVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVGKAED 90
Query: 241 TRKVV----ESLGHFDALVNNAAV-AVCEPFLDCSPSNFDKTFDVNVKA-VLNISQVVAR 402
++V E G D LV +A V + L S +DK VNVK+ L +SQ++
Sbjct: 91 REQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLLSQLLP- 149
Query: 403 KMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPT 582
+EN+ GA++ +SS A+ + +Y+ SK AL LTR +ALEL P IRVN + P
Sbjct: 150 -YMENR-RGAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIRVNCVVPG 207
Query: 583 VIMTEMAKVGWSDPIKANEMLSKIPLGRFGEISEVXNAVVFLLS 714
+I T+ +KV + L R GE + V FL S
Sbjct: 208 IIKTDFSKVFHGNESLWKNFKEHHQLQRIGESEDCAGIVSFLCS 251
>AF244132-1|AAG33703.1| 280|Homo sapiens short-chain alcohol
dehydrogenase protein.
Length = 280
Score = 79.0 bits (186), Expect = 2e-14
Identities = 71/224 (31%), Positives = 106/224 (47%), Gaps = 10/224 (4%)
Frame = +1
Query: 73 LVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLE----SLQSEYPSIDIVDVDIGDWEK 240
+VT L R GA++V SR + +++ LQ E S+ + +G E
Sbjct: 40 VVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVGKAED 99
Query: 241 TRKVV----ESLGHFDALVNNAAV-AVCEPFLDCSPSNFDKTFDVNVKA-VLNISQVVAR 402
++V E G D LV +A V + L S +DK VNVK+ L +SQ++
Sbjct: 100 REQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLLSQLLP- 158
Query: 403 KMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPT 582
+EN+ GA++ +SS A+ + +Y+ SK AL LTR +ALEL P IRVN + P
Sbjct: 159 -YMENR-RGAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIRVNCVVPG 216
Query: 583 VIMTEMAKVGWSDPIKANEMLSKIPLGRFGEISEVXNAVVFLLS 714
+I T+ +KV + L R GE + V FL S
Sbjct: 217 IIKTDFSKVFHGNESLWKNFKEHHQLQRIGESEDCAGIVSFLCS 260
>AK222857-1|BAD96577.1| 280|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 isoform 2 variant protein.
Length = 280
Score = 78.2 bits (184), Expect = 3e-14
Identities = 70/223 (31%), Positives = 102/223 (45%), Gaps = 9/223 (4%)
Frame = +1
Query: 73 LVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLE----SLQSEYPSIDIVDVDIGDWEK 240
+VT L R GA++V SR + +++ LQ E S+ + +G E
Sbjct: 40 VVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVGKAED 99
Query: 241 TRKVV----ESLGHFDALVNNAAV-AVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARK 405
++V E G D LV +A V + L S +DK VNVK+ + +
Sbjct: 100 REQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPAPLLSQLLPY 159
Query: 406 MIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTV 585
M EN+ GA++ +SS A+ + +YS SK AL LTR +ALEL P IRVN + P +
Sbjct: 160 M-ENR-RGAVILVSSVAAYNPVVALGVYSVSKTALLGLTRTLALELAPKDIRVNCVVPGI 217
Query: 586 IMTEMAKVGWSDPIKANEMLSKIPLGRFGEISEVXNAVVFLLS 714
I T+ +KV + L R GE + V FL S
Sbjct: 218 IKTDFSKVFHGNESLWKNFKEHHQLQRIGESEDCAGIVSFLCS 260
>DQ325464-1|ABC61320.1| 244|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase B1 isoform protein.
Length = 244
Score = 77.4 bits (182), Expect = 5e-14
Identities = 44/123 (35%), Positives = 68/123 (55%)
Frame = +1
Query: 349 TFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRA 528
T D+NVKA +++ V +M E + G++V +SS A+ + + Y+ SK AL LT+
Sbjct: 103 TLDINVKAPALMTKAVVPEM-EKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKT 161
Query: 529 MALELGPYGIRVNAINPTVIMTEMAKVGWSDPIKANEMLSKIPLGRFGEISEVXNAVVFL 708
+A+EL P IRVN + P +I T +++ W D K M + + R GE + V FL
Sbjct: 162 LAIELAPRNIRVNCLAPGLIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFL 221
Query: 709 LSE 717
SE
Sbjct: 222 CSE 224
>BC033650-1|AAH33650.1| 237|Homo sapiens carbonyl reductase 4
protein.
Length = 237
Score = 74.9 bits (176), Expect = 3e-13
Identities = 53/162 (32%), Positives = 78/162 (48%), Gaps = 1/162 (0%)
Frame = +1
Query: 229 DWEKTRKVVES-LGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARK 405
D + T + +E LG + LVN A + + + N+ + + R
Sbjct: 62 DVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRT 121
Query: 406 MIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTV 585
MI+ + G+IVN+ S ++YSASK L +RA+A E+ IRVN + P
Sbjct: 122 MIQQQG-GSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGF 180
Query: 586 IMTEMAKVGWSDPIKANEMLSKIPLGRFGEISEVXNAVVFLL 711
+ T+M K +K + IPLGRFGE EV +AVVFLL
Sbjct: 181 VHTDMTK-----DLKEEHLKKNIPLGRFGETIEVAHAVVFLL 217
>BC021973-1|AAH21973.1| 237|Homo sapiens carbonyl reductase 4
protein.
Length = 237
Score = 74.9 bits (176), Expect = 3e-13
Identities = 53/162 (32%), Positives = 78/162 (48%), Gaps = 1/162 (0%)
Frame = +1
Query: 229 DWEKTRKVVES-LGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARK 405
D + T + +E LG + LVN A + + + N+ + + R
Sbjct: 62 DVQNTFEEMEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRT 121
Query: 406 MIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTV 585
MI+ + G+IVN+ S ++YSASK L +RA+A E+ IRVN + P
Sbjct: 122 MIQQQG-GSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGF 180
Query: 586 IMTEMAKVGWSDPIKANEMLSKIPLGRFGEISEVXNAVVFLL 711
+ T+M K +K + IPLGRFGE EV +AVVFLL
Sbjct: 181 VHTDMTK-----DLKEEHLKKNIPLGRFGETIEVAHAVVFLL 217
>BC002786-1|AAH02786.1| 300|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 protein.
Length = 300
Score = 74.1 bits (174), Expect = 5e-13
Identities = 63/189 (33%), Positives = 96/189 (50%), Gaps = 10/189 (5%)
Frame = +1
Query: 73 LVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLE----SLQSEYPSIDIVDVDIGDWEK 240
+VT L R GA++V SR + +++ LQ E S+ + +G E
Sbjct: 40 VVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVGKAED 99
Query: 241 TRKVV----ESLGHFDALVNNAAV-AVCEPFLDCSPSNFDKTFDVNVKA-VLNISQVVAR 402
++V E G D LV +A V + L S +DK VNVK+ L +SQ++
Sbjct: 100 REQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLLSQLLP- 158
Query: 403 KMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPT 582
+EN+ GA++ +SS A+ + +Y+ SK AL LTR +ALEL P IRVN + P
Sbjct: 159 -YMENR-RGAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIRVNCVVPG 216
Query: 583 VIMTEMAKV 609
+I T+ +KV
Sbjct: 217 IIKTDFSKV 225
>X63657-1|CAA45197.1| 332|Homo sapiens FVT1 protein.
Length = 332
Score = 72.9 bits (171), Expect = 1e-12
Identities = 56/190 (29%), Positives = 84/190 (44%), Gaps = 13/190 (6%)
Frame = +1
Query: 49 ISFKGKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVD---- 216
++ G ++VT E ++ GA I ++R L + E I D
Sbjct: 28 LALPGAHVVVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKEIEMHSINDKQVV 87
Query: 217 ----VDIG-DWEKTRKVV----ESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVK 369
VD+ D+ + V+ E LG D LVN A +AV F D S F++ +N
Sbjct: 88 LCISVDVSQDYNQVENVIKQAQEKLGPVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYL 147
Query: 370 AVLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGP 549
+ S+ V M E + G IV +SSQA + L T YSASK A+ L A+ +E+ P
Sbjct: 148 GSVYPSRAVITTMKERRV-GRIVFVSSQAGQLGLFGFTAYSASKFAIRGLAEALQMEVKP 206
Query: 550 YGIRVNAINP 579
Y + + P
Sbjct: 207 YNVYITVAYP 216
>BT006782-1|AAP35428.1| 332|Homo sapiens follicular lymphoma
variant translocation 1 protein.
Length = 332
Score = 72.9 bits (171), Expect = 1e-12
Identities = 56/190 (29%), Positives = 84/190 (44%), Gaps = 13/190 (6%)
Frame = +1
Query: 49 ISFKGKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVD---- 216
++ G ++VT E ++ GA I ++R L + E I D
Sbjct: 28 LALPGAHVVVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKEIEMHSINDKQVV 87
Query: 217 ----VDIG-DWEKTRKVV----ESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVK 369
VD+ D+ + V+ E LG D LVN A +AV F D S F++ +N
Sbjct: 88 LCISVDVSQDYNQVENVIKQAQEKLGPVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYL 147
Query: 370 AVLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGP 549
+ S+ V M E + G IV +SSQA + L T YSASK A+ L A+ +E+ P
Sbjct: 148 GSVYPSRAVITTMKERRV-GRIVFVSSQAGQLGLFGFTAYSASKFAIRGLAEALQMEVKP 206
Query: 550 YGIRVNAINP 579
Y + + P
Sbjct: 207 YNVYITVAYP 216
>BC008797-1|AAH08797.1| 332|Homo sapiens follicular lymphoma
variant translocation 1 protein.
Length = 332
Score = 72.9 bits (171), Expect = 1e-12
Identities = 56/190 (29%), Positives = 84/190 (44%), Gaps = 13/190 (6%)
Frame = +1
Query: 49 ISFKGKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVD---- 216
++ G ++VT E ++ GA I ++R L + E I D
Sbjct: 28 LALPGAHVVVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKEIEMHSINDKQVV 87
Query: 217 ----VDIG-DWEKTRKVV----ESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVK 369
VD+ D+ + V+ E LG D LVN A +AV F D S F++ +N
Sbjct: 88 LCISVDVSQDYNQVENVIKQAQEKLGPVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYL 147
Query: 370 AVLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGP 549
+ S+ V M E + G IV +SSQA + L T YSASK A+ L A+ +E+ P
Sbjct: 148 GSVYPSRAVITTMKERRV-GRIVFVSSQAGQLGLFGFTAYSASKFAIRGLAEALQMEVKP 206
Query: 550 YGIRVNAINP 579
Y + + P
Sbjct: 207 YNVYITVAYP 216
>BC000663-1|AAH00663.2| 230|Homo sapiens dehydrogenase/reductase
(SDR family) member 4 like 2 protein.
Length = 230
Score = 69.7 bits (163), Expect = 1e-11
Identities = 58/194 (29%), Positives = 95/194 (48%), Gaps = 9/194 (4%)
Frame = +1
Query: 64 KXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLE----SLQSEYPSIDIVDVDIGD 231
K LVT L + A++V SR + +++ +LQ E S+ +G
Sbjct: 31 KVALVTASTDGIGFAIARRLAQDRAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGK 90
Query: 232 WEKTRKVVESL----GHFDALVNNAAV-AVCEPFLDCSPSNFDKTFDVNVKAVLNISQVV 396
E ++V G D LV+NAAV +D + +DKT D+NVKA +++ V
Sbjct: 91 AEDRERLVAMAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVKAPALMTKAV 150
Query: 397 ARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAIN 576
+M E + G++V +SS A+ + + Y+ SK AL L +A+EL P IRVN ++
Sbjct: 151 VPEM-EKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLNNTLAIELAPRNIRVNCLH 209
Query: 577 PTVIMTEMAKVGWS 618
+ ++ +A G S
Sbjct: 210 --LDLSRLASAGCS 221
>BC011968-1|AAH11968.1| 244|Homo sapiens DECR2 protein protein.
Length = 244
Score = 68.9 bits (161), Expect = 2e-11
Identities = 46/157 (29%), Positives = 77/157 (49%), Gaps = 1/157 (0%)
Frame = +1
Query: 247 KVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTH 426
+ ++ G D L+N AA P S + F D++ N+S+V+ K +
Sbjct: 51 QALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVLYEKFFRDHG- 109
Query: 427 GAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIM-TEMA 603
G IVNI++ ++KAA+DA+TR +A+E GP IRVN++ P I TE
Sbjct: 110 GVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGL 169
Query: 604 KVGWSDPIKANEMLSKIPLGRFGEISEVXNAVVFLLS 714
+ + ++ PL R G +E+ ++V++L S
Sbjct: 170 RRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLAS 206
>BC010740-1|AAH10740.1| 292|Homo sapiens 2,4-dienoyl CoA reductase
2, peroxisomal protein.
Length = 292
Score = 68.9 bits (161), Expect = 2e-11
Identities = 46/157 (29%), Positives = 77/157 (49%), Gaps = 1/157 (0%)
Frame = +1
Query: 247 KVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTH 426
+ ++ G D L+N AA P S + F D++ N+S+V+ K +
Sbjct: 99 QALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVLYEKFFRDHG- 157
Query: 427 GAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIM-TEMA 603
G IVNI++ ++KAA+DA+TR +A+E GP IRVN++ P I TE
Sbjct: 158 GVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGL 217
Query: 604 KVGWSDPIKANEMLSKIPLGRFGEISEVXNAVVFLLS 714
+ + ++ PL R G +E+ ++V++L S
Sbjct: 218 RRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLAS 254
>AL023881-5|CAB92744.1| 292|Homo sapiens 2,4-dienoyl CoA reductase
2, peroxisomal protein.
Length = 292
Score = 68.9 bits (161), Expect = 2e-11
Identities = 46/157 (29%), Positives = 77/157 (49%), Gaps = 1/157 (0%)
Frame = +1
Query: 247 KVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTH 426
+ ++ G D L+N AA P S + F D++ N+S+V+ K +
Sbjct: 99 QALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVLYEKFFRDHG- 157
Query: 427 GAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIM-TEMA 603
G IVNI++ ++KAA+DA+TR +A+E GP IRVN++ P I TE
Sbjct: 158 GVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGL 217
Query: 604 KVGWSDPIKANEMLSKIPLGRFGEISEVXNAVVFLLS 714
+ + ++ PL R G +E+ ++V++L S
Sbjct: 218 RRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLAS 254
>AL023881-4|CAI95592.1| 280|Homo sapiens 2,4-dienoyl CoA reductase
2, peroxisomal protein.
Length = 280
Score = 68.9 bits (161), Expect = 2e-11
Identities = 46/157 (29%), Positives = 77/157 (49%), Gaps = 1/157 (0%)
Frame = +1
Query: 247 KVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTH 426
+ ++ G D L+N AA P S + F D++ N+S+V+ K +
Sbjct: 87 QALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVLYEKFFRDHG- 145
Query: 427 GAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIM-TEMA 603
G IVNI++ ++KAA+DA+TR +A+E GP IRVN++ P I TE
Sbjct: 146 GVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGL 205
Query: 604 KVGWSDPIKANEMLSKIPLGRFGEISEVXNAVVFLLS 714
+ + ++ PL R G +E+ ++V++L S
Sbjct: 206 RRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLAS 242
>AJ293009-1|CAC05664.1| 292|Homo sapiens peroxisomal
2,4-dienoyl-CoA reductase protein.
Length = 292
Score = 68.9 bits (161), Expect = 2e-11
Identities = 46/157 (29%), Positives = 77/157 (49%), Gaps = 1/157 (0%)
Frame = +1
Query: 247 KVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTH 426
+ ++ G D L+N AA P S + F D++ N+S+V+ K +
Sbjct: 99 QALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVLYEKFFRDHG- 157
Query: 427 GAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIM-TEMA 603
G IVNI++ ++KAA+DA+TR +A+E GP IRVN++ P I TE
Sbjct: 158 GVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGL 217
Query: 604 KVGWSDPIKANEMLSKIPLGRFGEISEVXNAVVFLLS 714
+ + ++ PL R G +E+ ++V++L S
Sbjct: 218 RRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLAS 254
>AE006463-11|AAK61231.1| 292|Homo sapiens 2-4-dienoyl-Coenzyme A
reductase 2 peroxisomal like protein.
Length = 292
Score = 68.9 bits (161), Expect = 2e-11
Identities = 46/157 (29%), Positives = 77/157 (49%), Gaps = 1/157 (0%)
Frame = +1
Query: 247 KVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTH 426
+ ++ G D L+N AA P S + F D++ N+S+V+ K +
Sbjct: 99 QALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVLYEKFFRDHG- 157
Query: 427 GAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIM-TEMA 603
G IVNI++ ++KAA+DA+TR +A+E GP IRVN++ P I TE
Sbjct: 158 GVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGL 217
Query: 604 KVGWSDPIKANEMLSKIPLGRFGEISEVXNAVVFLLS 714
+ + ++ PL R G +E+ ++V++L S
Sbjct: 218 RRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLAS 254
>BC012043-1|AAH12043.1| 312|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 12 protein.
Length = 312
Score = 66.5 bits (155), Expect = 9e-11
Identities = 55/197 (27%), Positives = 95/197 (48%), Gaps = 14/197 (7%)
Frame = +1
Query: 61 GKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYP----------SIDI 210
G+ +VT EL + G +V +SR++ L+ + SE ++D
Sbjct: 50 GEWAVVTGSTDGIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKFKVETRTIAVDF 109
Query: 211 VDVDIGDWEKTRKVVESLGHFDALVNNAAVAVCEP--FLDCSPSN--FDKTFDVNVKAVL 378
DI D KT +G LVNN ++ P FLD + K ++N+ +V
Sbjct: 110 ASEDIYDKIKTGLAGLEIG---ILVNNVGMSYEYPEYFLDVPDLDNVIKKMININILSVC 166
Query: 379 NISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGI 558
++Q+V M+E ++ GAI+NISS + + TIYSA+K +D ++ + E G+
Sbjct: 167 KMTQLVLPGMVE-RSKGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCLHEEYRSKGV 225
Query: 559 RVNAINPTVIMTEMAKV 609
V ++ P + T++AK+
Sbjct: 226 FVQSVLPYFVATKLAKI 242
>AK222881-1|BAD96601.1| 312|Homo sapiens steroid dehydrogenase
homolog protein.
Length = 312
Score = 66.5 bits (155), Expect = 9e-11
Identities = 55/197 (27%), Positives = 95/197 (48%), Gaps = 14/197 (7%)
Frame = +1
Query: 61 GKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYP----------SIDI 210
G+ +VT EL + G +V +SR++ L+ + SE ++D
Sbjct: 50 GEWAVVTGSTDGIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKFKVETRTIAVDF 109
Query: 211 VDVDIGDWEKTRKVVESLGHFDALVNNAAVAVCEP--FLDCSPSN--FDKTFDVNVKAVL 378
DI D KT +G LVNN ++ P FLD + K ++N+ +V
Sbjct: 110 ASEDIYDKIKTGLAGLEIG---ILVNNVGMSYEYPEYFLDVPDLDNVIKKMININILSVC 166
Query: 379 NISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGI 558
++Q+V M+E ++ GAI+NISS + + TIYSA+K +D ++ + E G+
Sbjct: 167 KMTQLVLPGMVE-RSKGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCLHEEYRSKGV 225
Query: 559 RVNAINPTVIMTEMAKV 609
V ++ P + T++AK+
Sbjct: 226 FVQSVLPYFVATKLAKI 242
>U05659-1|AAC50066.1| 310|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 3 protein.
Length = 310
Score = 62.9 bits (146), Expect = 1e-09
Identities = 49/192 (25%), Positives = 90/192 (46%), Gaps = 10/192 (5%)
Frame = +1
Query: 61 GKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYP-----SIDIVDVDI 225
G+ ++T EL + G N+V +SRT LE++ +E S+ I+ D
Sbjct: 48 GQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKIIQADF 107
Query: 226 GDWEKTRKVVESLGHFDA--LVNNAAVA---VCEPFLDCSPSNFDKTFDVNVKAVLNISQ 390
+ + E L + LVNN + + FL+ +P N+ +V+ ++Q
Sbjct: 108 TKDDIYEHIKEKLAGLEIGILVNNVGMLPNLLPSHFLN-APDEIQSLIHCNITSVVKMTQ 166
Query: 391 VVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNA 570
++ + M E++ G I+NISS + +++YSASKA + A ++A+ E + +
Sbjct: 167 LILKHM-ESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKALQEEYKAKEVIIQV 225
Query: 571 INPTVIMTEMAK 606
+ P + T M K
Sbjct: 226 LTPYAVSTAMTK 237
>CR541894-1|CAG46692.1| 310|Homo sapiens HSD17B3 protein.
Length = 310
Score = 62.9 bits (146), Expect = 1e-09
Identities = 49/192 (25%), Positives = 90/192 (46%), Gaps = 10/192 (5%)
Frame = +1
Query: 61 GKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYP-----SIDIVDVDI 225
G+ ++T EL + G N+V +SRT LE++ +E S+ I+ D
Sbjct: 48 GQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKIIQADF 107
Query: 226 GDWEKTRKVVESLGHFDA--LVNNAAVA---VCEPFLDCSPSNFDKTFDVNVKAVLNISQ 390
+ + E L + LVNN + + FL+ +P N+ +V+ ++Q
Sbjct: 108 TKDDIYEHIKEKLAGLEIGILVNNVGMLPNLLPSHFLN-APDEIQSLIHCNITSVVKMTQ 166
Query: 391 VVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNA 570
++ + M E++ G I+NISS + +++YSASKA + A ++A+ E + +
Sbjct: 167 LILKHM-ESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKALQEEYKAKEVIIQV 225
Query: 571 INPTVIMTEMAK 606
+ P + T M K
Sbjct: 226 LTPYAVSTAMTK 237
>BC034281-1|AAH34281.1| 310|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 3 protein.
Length = 310
Score = 62.9 bits (146), Expect = 1e-09
Identities = 49/192 (25%), Positives = 90/192 (46%), Gaps = 10/192 (5%)
Frame = +1
Query: 61 GKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYP-----SIDIVDVDI 225
G+ ++T EL + G N+V +SRT LE++ +E S+ I+ D
Sbjct: 48 GQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKIIQADF 107
Query: 226 GDWEKTRKVVESLGHFDA--LVNNAAVA---VCEPFLDCSPSNFDKTFDVNVKAVLNISQ 390
+ + E L + LVNN + + FL+ +P N+ +V+ ++Q
Sbjct: 108 TKDDIYEHIKEKLAGLEIGILVNNVGMLPNLLPSHFLN-APDEIQSLIHCNITSVVKMTQ 166
Query: 391 VVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNA 570
++ + M E++ G I+NISS + +++YSASKA + A ++A+ E + +
Sbjct: 167 LILKHM-ESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKALQEEYKAKEVIIQV 225
Query: 571 INPTVIMTEMAK 606
+ P + T M K
Sbjct: 226 LTPYAVSTAMTK 237
>AY341031-1|AAP88937.1| 310|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 3 protein.
Length = 310
Score = 62.9 bits (146), Expect = 1e-09
Identities = 49/192 (25%), Positives = 90/192 (46%), Gaps = 10/192 (5%)
Frame = +1
Query: 61 GKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYP-----SIDIVDVDI 225
G+ ++T EL + G N+V +SRT LE++ +E S+ I+ D
Sbjct: 48 GQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKIIQADF 107
Query: 226 GDWEKTRKVVESLGHFDA--LVNNAAVA---VCEPFLDCSPSNFDKTFDVNVKAVLNISQ 390
+ + E L + LVNN + + FL+ +P N+ +V+ ++Q
Sbjct: 108 TKDDIYEHIKEKLAGLEIGILVNNVGMLPNLLPSHFLN-APDEIQSLIHCNITSVVKMTQ 166
Query: 391 VVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNA 570
++ + M E++ G I+NISS + +++YSASKA + A ++A+ E + +
Sbjct: 167 LILKHM-ESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKALQEEYKAKEVIIQV 225
Query: 571 INPTVIMTEMAK 606
+ P + T M K
Sbjct: 226 LTPYAVSTAMTK 237
>AL160269-3|CAH71615.1| 310|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 3 protein.
Length = 310
Score = 62.9 bits (146), Expect = 1e-09
Identities = 49/192 (25%), Positives = 90/192 (46%), Gaps = 10/192 (5%)
Frame = +1
Query: 61 GKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYP-----SIDIVDVDI 225
G+ ++T EL + G N+V +SRT LE++ +E S+ I+ D
Sbjct: 48 GQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKIIQADF 107
Query: 226 GDWEKTRKVVESLGHFDA--LVNNAAVA---VCEPFLDCSPSNFDKTFDVNVKAVLNISQ 390
+ + E L + LVNN + + FL+ +P N+ +V+ ++Q
Sbjct: 108 TKDDIYEHIKEKLAGLEIGILVNNVGMLPNLLPSHFLN-APDEIQSLIHCNITSVVKMTQ 166
Query: 391 VVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNA 570
++ + M E++ G I+NISS + +++YSASKA + A ++A+ E + +
Sbjct: 167 LILKHM-ESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKALQEEYKAKEVIIQV 225
Query: 571 INPTVIMTEMAK 606
+ P + T M K
Sbjct: 226 LTPYAVSTAMTK 237
>BC002529-1|AAH02529.1| 303|Homo sapiens peroxisomal
trans-2-enoyl-CoA reductase protein.
Length = 303
Score = 62.1 bits (144), Expect = 2e-09
Identities = 64/235 (27%), Positives = 101/235 (42%), Gaps = 16/235 (6%)
Frame = +1
Query: 58 KGKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLES----LQSEYPS-----IDI 210
+G+ +VT EL G+N+V SR L+S LQ+ P +
Sbjct: 17 QGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIP 76
Query: 211 VDVDIGDWEKTRKVVES----LGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVL 378
+ +I + E+ +V+S G + LVNN P S + + N+
Sbjct: 77 IQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTF 136
Query: 379 NISQVVARKMIENKTHG-AIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYG 555
+ + V + K HG +IVNI +KA A++A + LT+++ALE G
Sbjct: 137 YMCKAVYSSWM--KEHGGSIVNIIVP-TKAGFPLAVHSGAARAGVYNLTKSLALEWACSG 193
Query: 556 IRVNAINPTVIMTEMAKVGWSDPIKA--NEMLSKIPLGRFGEISEVXNAVVFLLS 714
IR+N + P VI ++ A + ++ KIP R G EV + V FLLS
Sbjct: 194 IRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLS 248
>AF232009-1|AAF69798.1| 303|Homo sapiens peroxisomal trans 2-enoyl
CoA reductase protein.
Length = 303
Score = 62.1 bits (144), Expect = 2e-09
Identities = 64/235 (27%), Positives = 101/235 (42%), Gaps = 16/235 (6%)
Frame = +1
Query: 58 KGKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLES----LQSEYPS-----IDI 210
+G+ +VT EL G+N+V SR L+S LQ+ P +
Sbjct: 17 QGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIP 76
Query: 211 VDVDIGDWEKTRKVVES----LGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVL 378
+ +I + E+ +V+S G + LVNN P S + + N+
Sbjct: 77 IQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTF 136
Query: 379 NISQVVARKMIENKTHG-AIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYG 555
+ + V + K HG +IVNI +KA A++A + LT+++ALE G
Sbjct: 137 YMCKAVYSSWM--KEHGGSIVNIIVP-TKAGFPLAVHSGAARAGVYNLTKSLALEWACSG 193
Query: 556 IRVNAINPTVIMTEMAKVGWSDPIKA--NEMLSKIPLGRFGEISEVXNAVVFLLS 714
IR+N + P VI ++ A + ++ KIP R G EV + V FLLS
Sbjct: 194 IRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLS 248
>AF212234-1|AAK14920.1| 322|Homo sapiens HPDHase protein.
Length = 322
Score = 62.1 bits (144), Expect = 2e-09
Identities = 64/235 (27%), Positives = 101/235 (42%), Gaps = 16/235 (6%)
Frame = +1
Query: 58 KGKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLES----LQSEYPS-----IDI 210
+G+ +VT EL G+N+V SR L+S LQ+ P +
Sbjct: 36 QGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIP 95
Query: 211 VDVDIGDWEKTRKVVES----LGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVL 378
+ +I + E+ +V+S G + LVNN P S + + N+
Sbjct: 96 IQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTF 155
Query: 379 NISQVVARKMIENKTHG-AIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYG 555
+ + V + K HG +IVNI +KA A++A + LT+++ALE G
Sbjct: 156 YMCKAVYSSWM--KEHGGSIVNIIVP-TKAGFPLAVHSGAARAGVYNLTKSLALEWACSG 212
Query: 556 IRVNAINPTVIMTEMAKVGWSDPIKA--NEMLSKIPLGRFGEISEVXNAVVFLLS 714
IR+N + P VI ++ A + ++ KIP R G EV + V FLLS
Sbjct: 213 IRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLS 267
>AC010686-2|AAY14657.1| 303|Homo sapiens unknown protein.
Length = 303
Score = 62.1 bits (144), Expect = 2e-09
Identities = 64/235 (27%), Positives = 101/235 (42%), Gaps = 16/235 (6%)
Frame = +1
Query: 58 KGKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLES----LQSEYPS-----IDI 210
+G+ +VT EL G+N+V SR L+S LQ+ P +
Sbjct: 17 QGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIP 76
Query: 211 VDVDIGDWEKTRKVVES----LGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVL 378
+ +I + E+ +V+S G + LVNN P S + + N+
Sbjct: 77 IQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTF 136
Query: 379 NISQVVARKMIENKTHG-AIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYG 555
+ + V + K HG +IVNI +KA A++A + LT+++ALE G
Sbjct: 137 YMCKAVYSSWM--KEHGGSIVNIIVP-TKAGFPLAVHSGAARAGVYNLTKSLALEWACSG 193
Query: 556 IRVNAINPTVIMTEMAKVGWSDPIKA--NEMLSKIPLGRFGEISEVXNAVVFLLS 714
IR+N + P VI ++ A + ++ KIP R G EV + V FLLS
Sbjct: 194 IRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLS 248
>BC104218-1|AAI04219.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 61.7 bits (143), Expect = 3e-09
Identities = 57/190 (30%), Positives = 81/190 (42%), Gaps = 10/190 (5%)
Frame = +1
Query: 61 GKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDI--GDW 234
G+ +V+ EL G NI+ +SR L+ + + V+ DI D+
Sbjct: 67 GRWAVVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADF 126
Query: 235 EKTRKVV----ESLGHFDA--LVNNAAVAVCEP--FLDCSPSNFDKTFDVNVKAVLNISQ 390
R++ E+L D LVNN V P F S +VN+ A +
Sbjct: 127 SSGREIYLPIREALKDKDVGILVNNVGVFYPYPQYFTQLSEDKLWDIINVNIAAASLMVH 186
Query: 391 VVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNA 570
VV M+E K GAIV ISS + +SASKA LD +RA+ E GI V +
Sbjct: 187 VVLPGMVERKK-GAIVTISSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQS 245
Query: 571 INPTVIMTEM 600
+ P + T M
Sbjct: 246 LIPFYVATSM 255
>AY028377-1|AAK16927.1| 309|Homo sapiens steroid dehydrogenase-like
protein protein.
Length = 309
Score = 61.7 bits (143), Expect = 3e-09
Identities = 57/190 (30%), Positives = 81/190 (42%), Gaps = 10/190 (5%)
Frame = +1
Query: 61 GKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDI--GDW 234
G+ +V+ EL G NI+ +SR L+ + + V+ DI D+
Sbjct: 46 GRWAVVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADF 105
Query: 235 EKTRKVV----ESLGHFDA--LVNNAAVAVCEP--FLDCSPSNFDKTFDVNVKAVLNISQ 390
R++ E+L D LVNN V P F S +VN+ A +
Sbjct: 106 SSGREIYLPIREALKDKDVGILVNNVGVFYPYPQYFTQLSEDKLWDIINVNIAAASLMVH 165
Query: 391 VVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNA 570
VV M+E K GAIV ISS + +SASKA LD +RA+ E GI V +
Sbjct: 166 VVLPGMVERKK-GAIVTISSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQS 224
Query: 571 INPTVIMTEM 600
+ P + T M
Sbjct: 225 LIPFYVATSM 234
>AK074878-1|BAC11262.1| 330|Homo sapiens protein ( Homo sapiens
cDNA FLJ90397 fis, clone NT2RP2005878, moderately
similar to PUTATIVE STEROID DEHYDROGENASE KIK-I (EC
1.1.1.-). ).
Length = 330
Score = 61.7 bits (143), Expect = 3e-09
Identities = 57/190 (30%), Positives = 81/190 (42%), Gaps = 10/190 (5%)
Frame = +1
Query: 61 GKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDI--GDW 234
G+ +V+ EL G NI+ +SR L+ + + V+ DI D+
Sbjct: 67 GRWAVVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADF 126
Query: 235 EKTRKVV----ESLGHFDA--LVNNAAVAVCEP--FLDCSPSNFDKTFDVNVKAVLNISQ 390
R++ E+L D LVNN V P F S +VN+ A +
Sbjct: 127 SSGREIYLPIREALKDKDVGILVNNVGVFYPYPQYFTQLSEDKLWDIINVNIAAASLMVH 186
Query: 391 VVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNA 570
VV M+E K GAIV ISS + +SASKA LD +RA+ E GI V +
Sbjct: 187 VVLPGMVERKK-GAIVTISSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQS 245
Query: 571 INPTVIMTEM 600
+ P + T M
Sbjct: 246 LIPFYVATSM 255
>AF237684-1|AAK15047.1| 309|Homo sapiens steroid dehydrogenase-like
protein protein.
Length = 309
Score = 61.7 bits (143), Expect = 3e-09
Identities = 57/190 (30%), Positives = 81/190 (42%), Gaps = 10/190 (5%)
Frame = +1
Query: 61 GKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDI--GDW 234
G+ +V+ EL G NI+ +SR L+ + + V+ DI D+
Sbjct: 46 GRWAVVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADF 105
Query: 235 EKTRKVV----ESLGHFDA--LVNNAAVAVCEP--FLDCSPSNFDKTFDVNVKAVLNISQ 390
R++ E+L D LVNN V P F S +VN+ A +
Sbjct: 106 SSGREIYLPIREALKDKDVGILVNNVGVFYPYPQYFTQLSEDKLWDIINVNIAAASLMVH 165
Query: 391 VVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNA 570
VV M+E K GAIV ISS + +SASKA LD +RA+ E GI V +
Sbjct: 166 VVLPGMVERKK-GAIVTISSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQS 224
Query: 571 INPTVIMTEM 600
+ P + T M
Sbjct: 225 LIPFYVATSM 234
>BC002731-1|AAH02731.2| 260|Homo sapiens short-chain
dehydrogenase/reductase protein.
Length = 260
Score = 61.3 bits (142), Expect = 3e-09
Identities = 65/236 (27%), Positives = 107/236 (45%), Gaps = 16/236 (6%)
Frame = +1
Query: 55 FKGKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSE-----YPSIDI-VD 216
++ + LVT L + G +V +RT ++E L +E YP I
Sbjct: 9 WRDRLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNIEELAAECKSAGYPGTLIPYR 68
Query: 217 VDIGDWEKTRKVVESL----GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNI 384
D+ + E + ++ D +NNA +A + L S S + F+VNV A+
Sbjct: 69 CDLSNEEDILSMFSAIRSQHSGVDICINNAGLARPDTLLSGSTSGWKDMFNVNVLALSIC 128
Query: 385 SQVVARKMIE-NKTHGAIVNISSQASKAALKDHT--IYSASKAALDALTRAMALEL--GP 549
++ + M E N G I+NI+S + L YSA+K A+ ALT + EL
Sbjct: 129 TREAYQSMKERNVDDGHIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREAQ 188
Query: 550 YGIRVNAINPTVIMTEMA-KVGWSDPIKANEMLSKIPLGRFGEISEVXNAVVFLLS 714
IR I+P V+ T+ A K+ DP KA ++ + +++E AV+++LS
Sbjct: 189 THIRATCISPGVVETQFAFKLHDKDPEKAAATYEQMKCLKPEDVAE---AVIYVLS 241
>AY358712-1|AAQ89074.1| 260|Homo sapiens ARPG836 protein.
Length = 260
Score = 61.3 bits (142), Expect = 3e-09
Identities = 65/236 (27%), Positives = 107/236 (45%), Gaps = 16/236 (6%)
Frame = +1
Query: 55 FKGKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSE-----YPSIDI-VD 216
++ + LVT L + G +V +RT ++E L +E YP I
Sbjct: 9 WRDRLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNIEELAAECKSAGYPGTLIPYR 68
Query: 217 VDIGDWEKTRKVVESL----GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNI 384
D+ + E + ++ D +NNA +A + L S S + F+VNV A+
Sbjct: 69 CDLSNEEDILSMFSAIRSQHSGVDICINNAGLARPDTLLSGSTSGWKDMFNVNVLALSIC 128
Query: 385 SQVVARKMIE-NKTHGAIVNISSQASKAALKDHT--IYSASKAALDALTRAMALEL--GP 549
++ + M E N G I+NI+S + L YSA+K A+ ALT + EL
Sbjct: 129 TREAYQSMKERNVDDGHIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREAQ 188
Query: 550 YGIRVNAINPTVIMTEMA-KVGWSDPIKANEMLSKIPLGRFGEISEVXNAVVFLLS 714
IR I+P V+ T+ A K+ DP KA ++ + +++E AV+++LS
Sbjct: 189 THIRATCISPGVVETQFAFKLHDKDPEKAAATYEQMKCLKPEDVAE---AVIYVLS 241
>DQ088988-1|AAZ85982.1| 118|Homo sapiens DHRS4L2 isoform 2 protein.
Length = 118
Score = 60.5 bits (140), Expect = 6e-09
Identities = 34/99 (34%), Positives = 58/99 (58%)
Frame = +1
Query: 319 LDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSAS 498
+D + +DKT D+NVKA +++ V +M E + G++V +SS A+ + + Y+ S
Sbjct: 3 MDVTEEVWDKTLDINVKAPALMTKAVVPEM-EKRGGGSVVIVSSIAAFSPSPGFSPYNVS 61
Query: 499 KAALDALTRAMALELGPYGIRVNAINPTVIMTEMAKVGW 615
K AL L +A+EL P IRVN ++ + ++ +A GW
Sbjct: 62 KTALLGLNNTLAIELAPRNIRVNCLH--LDLSRLASAGW 98
>BC106917-1|AAI06918.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 60.5 bits (140), Expect = 6e-09
Identities = 56/190 (29%), Positives = 81/190 (42%), Gaps = 10/190 (5%)
Frame = +1
Query: 61 GKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDI--GDW 234
G+ +V+ EL G NI+ +SR L+ + + V+ DI D+
Sbjct: 67 GRWAVVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADF 126
Query: 235 EKTRKVV----ESLGHFDA--LVNNAAVAVCEP--FLDCSPSNFDKTFDVNVKAVLNISQ 390
R++ E+L D LVNN V P F S +VN+ A +
Sbjct: 127 SSGREIYLPIREALKDKDVGILVNNVGVFYPYPQYFTQLSEDKLWDIINVNIAAASLMVH 186
Query: 391 VVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNA 570
VV M+E K GAIV ISS + +SAS+A LD +RA+ E GI V +
Sbjct: 187 VVLPGMVERKK-GAIVTISSGSCCKPTPQLAAFSASRAYLDHFSRALQYEYASKGIFVQS 245
Query: 571 INPTVIMTEM 600
+ P + T M
Sbjct: 246 LIPFYVATSM 255
>BC104219-1|AAI04220.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 60.5 bits (140), Expect = 6e-09
Identities = 56/190 (29%), Positives = 81/190 (42%), Gaps = 10/190 (5%)
Frame = +1
Query: 61 GKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDI--GDW 234
G+ +V+ EL G NI+ +SR L+ + + V+ DI D+
Sbjct: 67 GRWAVVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADF 126
Query: 235 EKTRKVV----ESLGHFDA--LVNNAAVAVCEP--FLDCSPSNFDKTFDVNVKAVLNISQ 390
R++ E+L D LVNN V P F S +VN+ A +
Sbjct: 127 SSGREIYLPIREALKDKDVGILVNNVGVFYPYPQYFTQLSEDKLWDIINVNIAAASLMVH 186
Query: 391 VVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNA 570
VV M+E K GAIV ISS + +SAS+A LD +RA+ E GI V +
Sbjct: 187 VVLPGMVERKK-GAIVTISSGSCCKPTPQLAAFSASRAYLDHFSRALQYEYASKGIFVQS 245
Query: 571 INPTVIMTEM 600
+ P + T M
Sbjct: 246 LIPFYVATSM 255
>BC018084-1|AAH18084.2| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 59.7 bits (138), Expect = 1e-08
Identities = 56/190 (29%), Positives = 80/190 (42%), Gaps = 10/190 (5%)
Frame = +1
Query: 61 GKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDI--GDW 234
G+ +V+ EL G NI+ +SR L+ + + V+ DI D+
Sbjct: 67 GRWAVVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADF 126
Query: 235 EKTRKVV----ESLGHFDA--LVNNAAVAVCEP--FLDCSPSNFDKTFDVNVKAVLNISQ 390
R++ E+L D LVNN V P F S +VN+ A +
Sbjct: 127 SSGREIYLPIREALKDKDVGILVNNVGVFYPYPQYFTQLSEDKLWDIINVNIAAASLMVH 186
Query: 391 VVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNA 570
VV M+E K GAIV ISS + +SASKA LD +RA+ E GI V +
Sbjct: 187 VVLPGMVERKK-GAIVTISSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQS 245
Query: 571 INPTVIMTEM 600
+ P + M
Sbjct: 246 LIPFYVAASM 255
>AJ250303-1|CAB89810.1| 303|Homo sapiens peroxisomal 2-enoyl-CoA
reductase protein.
Length = 303
Score = 58.8 bits (136), Expect = 2e-08
Identities = 64/235 (27%), Positives = 99/235 (42%), Gaps = 16/235 (6%)
Frame = +1
Query: 58 KGKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLES----LQSEYPS-----IDI 210
+G+ VT EL G+N+V SR L+S LQ+ P +
Sbjct: 17 QGQVAFVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIP 76
Query: 211 VDVDIGDWEKTRKVVES----LGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVL 378
+ +I + E+ +V+S G + LVNN P S + N+
Sbjct: 77 IQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLRTNLTGSF 136
Query: 379 NISQVVARKMIENKTHG-AIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYG 555
+ + V + K HG +IVNI +KA A++A + LT+++ALE G
Sbjct: 137 YMCKAVYSSWM--KEHGGSIVNIIVP-TKAGFPLAVHSGAARAGVYNLTKSLALEWACSG 193
Query: 556 IRVNAINPTVIMTEMAKVGWSDPIKA--NEMLSKIPLGRFGEISEVXNAVVFLLS 714
IR+N + P VI ++ A + ++ KIP R G EV + V FLLS
Sbjct: 194 IRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLS 248
>AB083038-1|BAB91014.1| 309|Homo sapiens retinal short chain
dehydrogenase reductase protein.
Length = 309
Score = 58.4 bits (135), Expect = 2e-08
Identities = 41/128 (32%), Positives = 59/128 (46%), Gaps = 3/128 (2%)
Frame = +1
Query: 226 GDWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARK 405
G + +V + +G L+NNA + + FLDC +K+FDVN KA L +
Sbjct: 104 GVYRVADQVKKEIGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLWTYKAFLPA 163
Query: 406 MIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALEL---GPYGIRVNAIN 576
MI N HG +V ISS A + + Y ASK A ++ +E GI+ +
Sbjct: 164 MIAN-DHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQKGIKTTIVC 222
Query: 577 PTVIMTEM 600
P I T M
Sbjct: 223 PFFIKTGM 230
>BC064525-1|AAH64525.1| 309|Homo sapiens epidermal retinal
dehydrogenase 2 protein.
Length = 309
Score = 58.0 bits (134), Expect = 3e-08
Identities = 41/128 (32%), Positives = 59/128 (46%), Gaps = 3/128 (2%)
Frame = +1
Query: 226 GDWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARK 405
G + +V + +G L+NNA + + FLDC +K+FDVN KA L +
Sbjct: 104 GVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLWTYKAFLPA 163
Query: 406 MIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALEL---GPYGIRVNAIN 576
MI N HG +V ISS A + + Y ASK A ++ +E GI+ +
Sbjct: 164 MIAN-DHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQKGIKTTIVC 222
Query: 577 PTVIMTEM 600
P I T M
Sbjct: 223 PFFIKTGM 230
>BC037219-1|AAH37219.2| 309|Homo sapiens epidermal retinal
dehydrogenase 2 protein.
Length = 309
Score = 58.0 bits (134), Expect = 3e-08
Identities = 41/128 (32%), Positives = 59/128 (46%), Gaps = 3/128 (2%)
Frame = +1
Query: 226 GDWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARK 405
G + +V + +G L+NNA + + FLDC +K+FDVN KA L +
Sbjct: 104 GVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLWTYKAFLPA 163
Query: 406 MIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALEL---GPYGIRVNAIN 576
MI N HG +V ISS A + + Y ASK A ++ +E GI+ +
Sbjct: 164 MIAN-DHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQKGIKTTIVC 222
Query: 577 PTVIMTEM 600
P I T M
Sbjct: 223 PFFIKTGM 230
>Z97054-8|CAI42653.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 261
Score = 56.8 bits (131), Expect = 7e-08
Identities = 47/158 (29%), Positives = 73/158 (46%), Gaps = 13/158 (8%)
Frame = +1
Query: 265 GHFDALVNNAAVAVCEPFLDCSPS------NFDKTFDVNVKAVLNISQVVARKMIENKT- 423
G D VN A +AV + +F + DVN+ N+ ++VA +M +N+
Sbjct: 83 GRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPD 142
Query: 424 ----HGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIM 591
G I+N +S A+ YSASK + +T +A +L P GIRV I P +
Sbjct: 143 QGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFG 202
Query: 592 TEMAKVGWSDPIK-ANEMLSKIPL-GRFGEISEVXNAV 699
T + S P K N + S++P R G+ +E + V
Sbjct: 203 TPLLT---SLPEKVCNFLASQVPFPSRLGDPAEYAHLV 237
>U96132-1|AAC51812.1| 261|Homo sapiens amyloid beta-peptide binding
protein protein.
Length = 261
Score = 56.8 bits (131), Expect = 7e-08
Identities = 47/158 (29%), Positives = 73/158 (46%), Gaps = 13/158 (8%)
Frame = +1
Query: 265 GHFDALVNNAAVAVCEPFLDCSPS------NFDKTFDVNVKAVLNISQVVARKMIENKT- 423
G D VN A +AV + +F + DVN+ N+ ++VA +M +N+
Sbjct: 83 GRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPD 142
Query: 424 ----HGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIM 591
G I+N +S A+ YSASK + +T +A +L P GIRV I P +
Sbjct: 143 QGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFG 202
Query: 592 TEMAKVGWSDPIK-ANEMLSKIPL-GRFGEISEVXNAV 699
T + S P K N + S++P R G+ +E + V
Sbjct: 203 TPLLT---SLPEKVCNFLASQVPFPSRLGDPAEYAHLV 237
>U73514-1|AAB68958.1| 261|Homo sapiens short-chain alcohol
dehydrogenase protein.
Length = 261
Score = 56.8 bits (131), Expect = 7e-08
Identities = 47/158 (29%), Positives = 73/158 (46%), Gaps = 13/158 (8%)
Frame = +1
Query: 265 GHFDALVNNAAVAVCEPFLDCSPS------NFDKTFDVNVKAVLNISQVVARKMIENKT- 423
G D VN A +AV + +F + DVN+ N+ ++VA +M +N+
Sbjct: 83 GRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPD 142
Query: 424 ----HGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIM 591
G I+N +S A+ YSASK + +T +A +L P GIRV I P +
Sbjct: 143 QGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFG 202
Query: 592 TEMAKVGWSDPIK-ANEMLSKIPL-GRFGEISEVXNAV 699
T + S P K N + S++P R G+ +E + V
Sbjct: 203 TPLLT---SLPEKVCNFLASQVPFPSRLGDPAEYAHLV 237
>CR457124-1|CAG33405.1| 325|Homo sapiens DKFZp566O084 protein.
Length = 325
Score = 56.8 bits (131), Expect = 7e-08
Identities = 40/150 (26%), Positives = 71/150 (47%), Gaps = 2/150 (1%)
Frame = +1
Query: 160 TRSHLESLQSEYPSIDIVDV-DIGDW-EKTRKVVESLGHFDALVNNAAVAVCEPFLDCSP 333
T SH +Q+ P + D+ D G ++++ G+ D LVNNA ++ +D +
Sbjct: 97 TASHATKVQTHKPYLVTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTV 156
Query: 334 SNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALD 513
+ + N + +++ + MI+ + G IV ISS K ++ + Y+ASK A
Sbjct: 157 DVDKRVMETNYFGPVALTKALLPSMIKRR-QGHIVAISSIQGKMSIPFRSAYAASKHATQ 215
Query: 514 ALTRAMALELGPYGIRVNAINPTVIMTEMA 603
A + E+ Y I V I+P I T ++
Sbjct: 216 AFFDCLRAEMEQYEIEVTVISPGYIHTNLS 245
>CR456723-1|CAG33004.1| 261|Homo sapiens HADH2 protein.
Length = 261
Score = 56.8 bits (131), Expect = 7e-08
Identities = 47/158 (29%), Positives = 73/158 (46%), Gaps = 13/158 (8%)
Frame = +1
Query: 265 GHFDALVNNAAVAVCEPFLDCSPS------NFDKTFDVNVKAVLNISQVVARKMIENKT- 423
G D VN A +AV + +F + DVN+ N+ ++VA +M +N+
Sbjct: 83 GRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPD 142
Query: 424 ----HGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIM 591
G I+N +S A+ YSASK + +T +A +L P GIRV I P +
Sbjct: 143 QGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFG 202
Query: 592 TEMAKVGWSDPIK-ANEMLSKIPL-GRFGEISEVXNAV 699
T + S P K N + S++P R G+ +E + V
Sbjct: 203 TPLLT---SLPEKVCNFLASQVPFPSRLGDPAEYAHLV 237
>BC009679-1|AAH09679.1| 325|Homo sapiens dehydrogenase/reductase
(SDR family) member 7B protein.
Length = 325
Score = 56.8 bits (131), Expect = 7e-08
Identities = 40/150 (26%), Positives = 71/150 (47%), Gaps = 2/150 (1%)
Frame = +1
Query: 160 TRSHLESLQSEYPSIDIVDV-DIGDW-EKTRKVVESLGHFDALVNNAAVAVCEPFLDCSP 333
T SH +Q+ P + D+ D G ++++ G+ D LVNNA ++ +D +
Sbjct: 97 TASHATKVQTHKPYLVTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTV 156
Query: 334 SNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALD 513
+ + N + +++ + MI+ + G IV ISS K ++ + Y+ASK A
Sbjct: 157 DVDKRVMETNYFGPVALTKALLPSMIKRR-QGHIVAISSIQGKMSIPFRSAYAASKHATQ 215
Query: 514 ALTRAMALELGPYGIRVNAINPTVIMTEMA 603
A + E+ Y I V I+P I T ++
Sbjct: 216 AFFDCLRAEMEQYEIEVTVISPGYIHTNLS 245
>BC004126-1|AAH04126.1| 325|Homo sapiens dehydrogenase/reductase
(SDR family) member 7B protein.
Length = 325
Score = 56.8 bits (131), Expect = 7e-08
Identities = 40/150 (26%), Positives = 71/150 (47%), Gaps = 2/150 (1%)
Frame = +1
Query: 160 TRSHLESLQSEYPSIDIVDV-DIGDW-EKTRKVVESLGHFDALVNNAAVAVCEPFLDCSP 333
T SH +Q+ P + D+ D G ++++ G+ D LVNNA ++ +D +
Sbjct: 97 TASHATKVQTHKPYLVTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTV 156
Query: 334 SNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALD 513
+ + N + +++ + MI+ + G IV ISS K ++ + Y+ASK A
Sbjct: 157 DVDKRVMETNYFGPVALTKALLPSMIKRR-QGHIVAISSIQGKMSIPFRSAYAASKHATQ 215
Query: 514 ALTRAMALELGPYGIRVNAINPTVIMTEMA 603
A + E+ Y I V I+P I T ++
Sbjct: 216 AFFDCLRAEMEQYEIEVTVISPGYIHTNLS 245
>BC000372-1|AAH00372.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 261
Score = 56.8 bits (131), Expect = 7e-08
Identities = 47/158 (29%), Positives = 73/158 (46%), Gaps = 13/158 (8%)
Frame = +1
Query: 265 GHFDALVNNAAVAVCEPFLDCSPS------NFDKTFDVNVKAVLNISQVVARKMIENKT- 423
G D VN A +AV + +F + DVN+ N+ ++VA +M +N+
Sbjct: 83 GRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPD 142
Query: 424 ----HGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIM 591
G I+N +S A+ YSASK + +T +A +L P GIRV I P +
Sbjct: 143 QGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFG 202
Query: 592 TEMAKVGWSDPIK-ANEMLSKIPL-GRFGEISEVXNAV 699
T + S P K N + S++P R G+ +E + V
Sbjct: 203 TPLLT---SLPEKVCNFLASQVPFPSRLGDPAEYAHLV 237
>AY358498-1|AAQ88862.1| 310|Homo sapiens DFIT212 protein.
Length = 310
Score = 56.8 bits (131), Expect = 7e-08
Identities = 40/150 (26%), Positives = 71/150 (47%), Gaps = 2/150 (1%)
Frame = +1
Query: 160 TRSHLESLQSEYPSIDIVDV-DIGDW-EKTRKVVESLGHFDALVNNAAVAVCEPFLDCSP 333
T SH +Q+ P + D+ D G ++++ G+ D LVNNA ++ +D +
Sbjct: 82 TASHATKVQTHKPYLVTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTV 141
Query: 334 SNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALD 513
+ + N + +++ + MI+ + G IV ISS K ++ + Y+ASK A
Sbjct: 142 DVDKRVMETNYFGPVALTKALLPSMIKRR-QGHIVAISSIQGKMSIPFRSAYAASKHATQ 200
Query: 514 ALTRAMALELGPYGIRVNAINPTVIMTEMA 603
A + E+ Y I V I+P I T ++
Sbjct: 201 AFFDCLRAEMEQYEIEVTVISPGYIHTNLS 230
>AY092415-1|AAM18189.1| 196|Homo sapiens endoplasmic
reticulum-associated amyloid beta peptide-binding
protein protein.
Length = 196
Score = 56.8 bits (131), Expect = 7e-08
Identities = 47/158 (29%), Positives = 73/158 (46%), Gaps = 13/158 (8%)
Frame = +1
Query: 265 GHFDALVNNAAVAVCEPFLDCSPS------NFDKTFDVNVKAVLNISQVVARKMIENKT- 423
G D VN A +AV + +F + DVN+ N+ ++VA +M +N+
Sbjct: 33 GRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPD 92
Query: 424 ----HGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIM 591
G I+N +S A+ YSASK + +T +A +L P GIRV I P +
Sbjct: 93 QGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFG 152
Query: 592 TEMAKVGWSDPIK-ANEMLSKIPL-GRFGEISEVXNAV 699
T + S P K N + S++P R G+ +E + V
Sbjct: 153 TPLLT---SLPEKVCNFLASQVPFPSRLGDPAEYAHLV 187
>AF151851-1|AAD34088.1| 291|Homo sapiens CGI-93 protein protein.
Length = 291
Score = 56.8 bits (131), Expect = 7e-08
Identities = 40/150 (26%), Positives = 71/150 (47%), Gaps = 2/150 (1%)
Frame = +1
Query: 160 TRSHLESLQSEYPSIDIVDV-DIGDW-EKTRKVVESLGHFDALVNNAAVAVCEPFLDCSP 333
T SH +Q+ P + D+ D G ++++ G+ D LVNNA ++ +D +
Sbjct: 102 TASHATKVQTHKPYLVTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTV 161
Query: 334 SNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALD 513
+ + N + +++ + MI+ + G IV ISS K ++ + Y+ASK A
Sbjct: 162 DVDKRVMETNYFGPVALTKALLPSMIKRR-QGHIVAISSIQGKMSIPFRSAYAASKHATQ 220
Query: 514 ALTRAMALELGPYGIRVNAINPTVIMTEMA 603
A + E+ Y I V I+P I T ++
Sbjct: 221 AFFDCLRAEMEQYEIEVTVISPGYIHTNLS 250
>AF069134-1|AAC39900.1| 261|Homo sapiens putative short-chain type
dehydrogenase/reductase protein.
Length = 261
Score = 56.8 bits (131), Expect = 7e-08
Identities = 47/158 (29%), Positives = 73/158 (46%), Gaps = 13/158 (8%)
Frame = +1
Query: 265 GHFDALVNNAAVAVCEPFLDCSPS------NFDKTFDVNVKAVLNISQVVARKMIENKT- 423
G D VN A +AV + +F + DVN+ N+ ++VA +M +N+
Sbjct: 83 GRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPD 142
Query: 424 ----HGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIM 591
G I+N +S A+ YSASK + +T +A +L P GIRV I P +
Sbjct: 143 QGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFG 202
Query: 592 TEMAKVGWSDPIK-ANEMLSKIPL-GRFGEISEVXNAV 699
T + S P K N + S++P R G+ +E + V
Sbjct: 203 TPLLT---SLPEKVCNFLASQVPFPSRLGDPAEYAHLV 237
>AF037438-1|AAC16419.1| 261|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 10/short chain L-3-hydroxyacyl-CoA
deh protein.
Length = 261
Score = 56.8 bits (131), Expect = 7e-08
Identities = 47/158 (29%), Positives = 73/158 (46%), Gaps = 13/158 (8%)
Frame = +1
Query: 265 GHFDALVNNAAVAVCEPFLDCSPS------NFDKTFDVNVKAVLNISQVVARKMIENKT- 423
G D VN A +AV + +F + DVN+ N+ ++VA +M +N+
Sbjct: 83 GRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPD 142
Query: 424 ----HGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIM 591
G I+N +S A+ YSASK + +T +A +L P GIRV I P +
Sbjct: 143 QGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFG 202
Query: 592 TEMAKVGWSDPIK-ANEMLSKIPL-GRFGEISEVXNAV 699
T + S P K N + S++P R G+ +E + V
Sbjct: 203 TPLLT---SLPEKVCNFLASQVPFPSRLGDPAEYAHLV 237
>AF035555-1|AAC15902.1| 261|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 10/short chain L-3-hydroxyacyl-CoA
deh protein.
Length = 261
Score = 56.8 bits (131), Expect = 7e-08
Identities = 47/158 (29%), Positives = 73/158 (46%), Gaps = 13/158 (8%)
Frame = +1
Query: 265 GHFDALVNNAAVAVCEPFLDCSPS------NFDKTFDVNVKAVLNISQVVARKMIENKT- 423
G D VN A +AV + +F + DVN+ N+ ++VA +M +N+
Sbjct: 83 GRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPD 142
Query: 424 ----HGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIM 591
G I+N +S A+ YSASK + +T +A +L P GIRV I P +
Sbjct: 143 QGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFG 202
Query: 592 TEMAKVGWSDPIK-ANEMLSKIPL-GRFGEISEVXNAV 699
T + S P K N + S++P R G+ +E + V
Sbjct: 203 TPLLT---SLPEKVCNFLASQVPFPSRLGDPAEYAHLV 237
>CR457356-1|CAG33637.1| 181|Homo sapiens MGC4172 protein.
Length = 181
Score = 56.0 bits (129), Expect = 1e-07
Identities = 49/153 (32%), Positives = 77/153 (50%), Gaps = 6/153 (3%)
Frame = +1
Query: 274 DALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIE-NKTHGAIVNISS 450
D +NNA +A + L S S + F+VNV A+ ++ + M E N G I+NI+S
Sbjct: 13 DICINNAGLARPDTLLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNVDDGHIININS 72
Query: 451 QASKAALKDHT--IYSASKAALDALTRAMALEL--GPYGIRVNAINPTVIMTEMA-KVGW 615
+ L YSA+K A+ ALT + EL IR I+P V+ T+ A K+
Sbjct: 73 MSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREAQTHIRATCISPGVVETQFAFKLHD 132
Query: 616 SDPIKANEMLSKIPLGRFGEISEVXNAVVFLLS 714
DP KA ++ + +++E AV+++LS
Sbjct: 133 KDPEKAAATYEQMKCLKPEDVAE---AVIYVLS 162
>AK057667-1|BAB71545.1| 231|Homo sapiens protein ( Homo sapiens
cDNA FLJ33105 fis, clone TRACH2000926, weakly similar to
PROBABLE OXIDOREDUCTASE EPHD (EC 1.-.-.-). ).
Length = 231
Score = 56.0 bits (129), Expect = 1e-07
Identities = 35/105 (33%), Positives = 51/105 (48%)
Frame = +1
Query: 226 GDWEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARK 405
G + +V + +G L+NNA + + FLDC +K+FDVN KA L +
Sbjct: 104 GVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLWTYKAFLPA 163
Query: 406 MIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALE 540
MI N HG +V ISS A + + Y ASK A ++ +E
Sbjct: 164 MIAN-DHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVE 207
>AK026196-1|BAB15390.1| 181|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22543 fis, clone HSI00212. ).
Length = 181
Score = 56.0 bits (129), Expect = 1e-07
Identities = 49/153 (32%), Positives = 77/153 (50%), Gaps = 6/153 (3%)
Frame = +1
Query: 274 DALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIE-NKTHGAIVNISS 450
D +NNA +A + L S S + F+VNV A+ ++ + M E N G I+NI+S
Sbjct: 13 DICINNAGLARPDTLLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNVDDGHIININS 72
Query: 451 QASKAALKDHT--IYSASKAALDALTRAMALEL--GPYGIRVNAINPTVIMTEMA-KVGW 615
+ L YSA+K A+ ALT + EL IR I+P V+ T+ A K+
Sbjct: 73 MSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREAQTHIRATCISPGVVETQFAFKLHD 132
Query: 616 SDPIKANEMLSKIPLGRFGEISEVXNAVVFLLS 714
DP KA ++ + +++E AV+++LS
Sbjct: 133 KDPEKAAATYEQMKCLKPEDVAE---AVIYVLS 162
>BT019371-1|AAV38178.1| 260|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 3 protein.
Length = 260
Score = 55.6 bits (128), Expect = 2e-07
Identities = 45/170 (26%), Positives = 82/170 (48%), Gaps = 10/170 (5%)
Frame = +1
Query: 61 GKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYP-----SIDIVDVDI 225
G+ ++T EL + G N+V +SRT LE++ +E S+ I+ D
Sbjct: 48 GQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKIIQADF 107
Query: 226 GDWEKTRKVVESLGHFDA--LVNNAAVA---VCEPFLDCSPSNFDKTFDVNVKAVLNISQ 390
+ + E L + LVNN + + FL+ +P N+ +V+ ++Q
Sbjct: 108 TKDDIYEHIKEKLAGLEIGILVNNVGMLPNLLPSHFLN-APDEIQSLIHCNITSVVKMTQ 166
Query: 391 VVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALE 540
++ + M E++ G I+NISS + +++YSASKA + A ++A+ E
Sbjct: 167 LILKHM-ESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKALQEE 215
>L76465-1|AAA89175.1| 266|Homo sapiens NAD+-dependent
15-hydroxyprostaglandin dehydrogenase protein.
Length = 266
Score = 55.2 bits (127), Expect = 2e-07
Identities = 45/161 (27%), Positives = 73/161 (45%), Gaps = 4/161 (2%)
Frame = +1
Query: 124 WRAGANIVALSRTRSHLESLQSEYPSIDIVDVDIGDWEKTRKVVESLGHFDALVNNAAVA 303
W A + + E ++ + D+ D + RKVV+ G D LVNNA V
Sbjct: 37 WNLEAGVQCKAALHEQFEPQKTLFIQCDVADQQQLR-DTFRKVVDHFGRLDILVNNAGVN 95
Query: 304 VCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENK--THGAIVNISSQASKAALKD 477
+ N++KT +N+ +V++ + + M + G I+N+SS A +
Sbjct: 96 --------NEKNWEKTLQINLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQ 147
Query: 478 HTIYSASKAALDALTR--AMALELGPYGIRVNAINPTVIMT 594
+Y ASK + TR A+A L G+R+NAI P + T
Sbjct: 148 QPVYCASKHGIVGFTRSAALAANLMNSGVRLNAICPGFVNT 188
>J05594-1|AAA89174.1| 266|Homo sapiens NAD+-dependent
15-hydroxyprostaglandin dehydrogenase protein.
Length = 266
Score = 55.2 bits (127), Expect = 2e-07
Identities = 45/161 (27%), Positives = 73/161 (45%), Gaps = 4/161 (2%)
Frame = +1
Query: 124 WRAGANIVALSRTRSHLESLQSEYPSIDIVDVDIGDWEKTRKVVESLGHFDALVNNAAVA 303
W A + + E ++ + D+ D + RKVV+ G D LVNNA V
Sbjct: 37 WNLEAGVQCKAALHEQFEPQKTLFIQCDVADQQQLR-DTFRKVVDHFGRLDILVNNAGVN 95
Query: 304 VCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENK--THGAIVNISSQASKAALKD 477
+ N++KT +N+ +V++ + + M + G I+N+SS A +
Sbjct: 96 --------NEKNWEKTLQINLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQ 147
Query: 478 HTIYSASKAALDALTR--AMALELGPYGIRVNAINPTVIMT 594
+Y ASK + TR A+A L G+R+NAI P + T
Sbjct: 148 QPVYCASKHGIVGFTRSAALAANLMNSGVRLNAICPGFVNT 188
>AF229845-1|AAF63160.1| 311|Homo sapiens photoreceptor outer
segment all-trans retinol dehydrogenase protein.
Length = 311
Score = 55.2 bits (127), Expect = 2e-07
Identities = 34/134 (25%), Positives = 65/134 (48%), Gaps = 1/134 (0%)
Frame = +1
Query: 199 SIDIVDVDIGDWEKTRKVVESL-GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAV 375
++ + +D+ E + + + G D LVNNA + + P S + FD N
Sbjct: 59 TLTVAQLDVCSDESVAQCLSCIQGEVDVLVNNAGMGLVGPLEGLSLAAMQNVFDTNFFGA 118
Query: 376 LNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYG 555
+ + + V M + + G IV ISS + + +Y+ASK AL+ ++A++L +
Sbjct: 119 VRLVKAVLPGM-KRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQLLQFN 177
Query: 556 IRVNAINPTVIMTE 597
I ++ + P ++TE
Sbjct: 178 IFISLVEPGPVVTE 191
>DQ903072-1|ABI75347.1| 266|Homo sapiens hydroxyprostaglandin
dehydrogenase 15-(NAD) protein.
Length = 266
Score = 54.4 bits (125), Expect = 4e-07
Identities = 40/121 (33%), Positives = 61/121 (50%), Gaps = 4/121 (3%)
Frame = +1
Query: 244 RKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENK- 420
RKVV+ G D LVNNA V + N++KT +N+ +V++ + + M +
Sbjct: 76 RKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVISGTYLGLDYMSKQNG 127
Query: 421 -THGAIVNISSQASKAALKDHTIYSASKAALDALTR--AMALELGPYGIRVNAINPTVIM 591
G I+N+SS A + +Y ASK + TR A+A L G+R+NAI P +
Sbjct: 128 GEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAICPGFVN 187
Query: 592 T 594
T
Sbjct: 188 T 188
>CR457309-1|CAG33590.1| 173|Homo sapiens DHRS6 protein.
Length = 173
Score = 54.4 bits (125), Expect = 4e-07
Identities = 35/133 (26%), Positives = 62/133 (46%)
Frame = +1
Query: 61 GKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDIGDWEK 240
GK I++T R GA ++A S L+ L+ +YP I +D+ ++
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELE-KYPGIQTRVLDVTKKKQ 64
Query: 241 TRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENK 420
+ + D L N A LDC ++D + ++NV+++ + + KM+ K
Sbjct: 65 IDQFASEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQK 124
Query: 421 THGAIVNISSQAS 459
+ G I+N+SS AS
Sbjct: 125 S-GNIINMSSVAS 136
>BC037277-1|AAH37277.1| 173|Homo sapiens BDH2 protein protein.
Length = 173
Score = 54.4 bits (125), Expect = 4e-07
Identities = 35/133 (26%), Positives = 62/133 (46%)
Frame = +1
Query: 61 GKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDIGDWEK 240
GK I++T R GA ++A S L+ L+ +YP I +D+ ++
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELE-KYPGIQTRVLDVTKKKQ 64
Query: 241 TRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENK 420
+ + D L N A LDC ++D + ++NV+++ + + KM+ K
Sbjct: 65 IDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQK 124
Query: 421 THGAIVNISSQAS 459
+ G I+N+SS AS
Sbjct: 125 S-GNIINMSSVAS 136
>BC018986-1|AAH18986.1| 266|Homo sapiens hydroxyprostaglandin
dehydrogenase 15-(NAD) protein.
Length = 266
Score = 54.4 bits (125), Expect = 4e-07
Identities = 40/121 (33%), Positives = 61/121 (50%), Gaps = 4/121 (3%)
Frame = +1
Query: 244 RKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENK- 420
RKVV+ G D LVNNA V + N++KT +N+ +V++ + + M +
Sbjct: 76 RKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVISGTYLGLDYMSKQNG 127
Query: 421 -THGAIVNISSQASKAALKDHTIYSASKAALDALTR--AMALELGPYGIRVNAINPTVIM 591
G I+N+SS A + +Y ASK + TR A+A L G+R+NAI P +
Sbjct: 128 GEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAICPGFVN 187
Query: 592 T 594
T
Sbjct: 188 T 188
>AK023323-1|BAB14526.1| 173|Homo sapiens protein ( Homo sapiens
cDNA FLJ13261 fis, clone OVARC1000885, weakly similar to
OXIDOREDUCTASE UCPA (EC 1.-.-.-). ).
Length = 173
Score = 54.4 bits (125), Expect = 4e-07
Identities = 35/133 (26%), Positives = 62/133 (46%)
Frame = +1
Query: 61 GKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSIDIVDVDIGDWEK 240
GK I++T R GA ++A S L+ L+ +YP I +D+ ++
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELE-KYPGIQTRVLDVTKKKQ 64
Query: 241 TRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENK 420
+ + D L N A LDC ++D + ++NV+++ + + KM+ K
Sbjct: 65 IDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQK 124
Query: 421 THGAIVNISSQAS 459
+ G I+N+SS AS
Sbjct: 125 S-GNIINMSSVAS 136
>AK027882-1|BAB55429.1| 177|Homo sapiens protein ( Homo sapiens
cDNA FLJ14976 fis, clone THYRO1001406, highly similar to
PUTATIVE STEROID DEHYDROGENASE KIK-I (EC 1.1.1.-). ).
Length = 177
Score = 52.4 bits (120), Expect = 2e-06
Identities = 28/88 (31%), Positives = 53/88 (60%)
Frame = +1
Query: 346 KTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTR 525
K ++N+ +V ++Q+V M+E ++ GAI+NISS + + TIYSA+K +D ++
Sbjct: 21 KMININILSVCKMTQLVLPGMVE-RSKGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQ 79
Query: 526 AMALELGPYGIRVNAINPTVIMTEMAKV 609
+ E G+ V ++ P + T++AK+
Sbjct: 80 CLHEEYRSKGVFVQSVLPYFVATKLAKI 107
>AY186250-1|AAO72314.1| 264|Homo sapiens 17-beta hydroxysteroid
dehydrogenase isoform 1 protein.
Length = 264
Score = 49.2 bits (112), Expect = 1e-05
Identities = 35/128 (27%), Positives = 55/128 (42%), Gaps = 3/128 (2%)
Frame = +1
Query: 232 WEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMI 411
W+ KV + +G +VNNA L KTF+VN+ I++ + M+
Sbjct: 66 WD-INKVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWITKALLPSMM 124
Query: 412 ENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALE---LGPYGIRVNAINPT 582
E + HG IV ++S + Y +SK A R + E LG GI+ + + P
Sbjct: 125 E-RNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGIKTSCLCPV 183
Query: 583 VIMTEMAK 606
+ T K
Sbjct: 184 FVNTGFTK 191
>BC036001-1|AAH36001.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 48.8 bits (111), Expect = 2e-05
Identities = 34/128 (26%), Positives = 53/128 (41%), Gaps = 3/128 (2%)
Frame = +1
Query: 232 WEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMI 411
+ +KV +G LVNNA V +KTF+VNV A ++ M
Sbjct: 101 YSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMT 160
Query: 412 ENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPY---GIRVNAINPT 582
+N HG IV ++S A ++ Y +SK A + + EL G++ + P
Sbjct: 161 KN-NHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPN 219
Query: 583 VIMTEMAK 606
+ T K
Sbjct: 220 FVNTGFIK 227
>BC021673-1|AAH21673.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 48.8 bits (111), Expect = 2e-05
Identities = 34/128 (26%), Positives = 53/128 (41%), Gaps = 3/128 (2%)
Frame = +1
Query: 232 WEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMI 411
+ +KV +G LVNNA V +KTF+VNV A ++ M
Sbjct: 101 YSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMT 160
Query: 412 ENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPY---GIRVNAINPT 582
+N HG IV ++S A ++ Y +SK A + + EL G++ + P
Sbjct: 161 KN-NHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPN 219
Query: 583 VIMTEMAK 606
+ T K
Sbjct: 220 FVNTGFIK 227
>BC016367-1|AAH16367.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 48.8 bits (111), Expect = 2e-05
Identities = 34/128 (26%), Positives = 53/128 (41%), Gaps = 3/128 (2%)
Frame = +1
Query: 232 WEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMI 411
+ +KV +G LVNNA V +KTF+VNV A ++ M
Sbjct: 101 YSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMT 160
Query: 412 ENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPY---GIRVNAINPT 582
+N HG IV ++S A ++ Y +SK A + + EL G++ + P
Sbjct: 161 KN-NHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPN 219
Query: 583 VIMTEMAK 606
+ T K
Sbjct: 220 FVNTGFIK 227
>BC014327-1|AAH14327.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 48.8 bits (111), Expect = 2e-05
Identities = 34/128 (26%), Positives = 53/128 (41%), Gaps = 3/128 (2%)
Frame = +1
Query: 232 WEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMI 411
+ +KV +G LVNNA V +KTF+VNV A ++ M
Sbjct: 101 YSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMT 160
Query: 412 ENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPY---GIRVNAINPT 582
+N HG IV ++S A ++ Y +SK A + + EL G++ + P
Sbjct: 161 KN-NHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPN 219
Query: 583 VIMTEMAK 606
+ T K
Sbjct: 220 FVNTGFIK 227
>AY358553-1|AAQ88917.1| 300|Homo sapiens KFLL207 protein.
Length = 300
Score = 48.8 bits (111), Expect = 2e-05
Identities = 34/128 (26%), Positives = 53/128 (41%), Gaps = 3/128 (2%)
Frame = +1
Query: 232 WEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMI 411
+ +KV +G LVNNA V +KTF+VNV A ++ M
Sbjct: 101 YSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMT 160
Query: 412 ENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPY---GIRVNAINPT 582
+N HG IV ++S A ++ Y +SK A + + EL G++ + P
Sbjct: 161 KN-NHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPN 219
Query: 583 VIMTEMAK 606
+ T K
Sbjct: 220 FVNTGFIK 227
>AK075348-1|BAC11560.1| 300|Homo sapiens protein ( Homo sapiens
cDNA PSEC0029 fis, clone NT2RP1000544, highly similar to
Retinal short-chain dehydrogenase/reductase 2. ).
Length = 300
Score = 48.8 bits (111), Expect = 2e-05
Identities = 34/128 (26%), Positives = 53/128 (41%), Gaps = 3/128 (2%)
Frame = +1
Query: 232 WEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMI 411
+ +KV +G LVNNA V +KTF+VNV A ++ M
Sbjct: 101 YSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMT 160
Query: 412 ENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPY---GIRVNAINPT 582
+N HG IV ++S A ++ Y +SK A + + EL G++ + P
Sbjct: 161 KN-NHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPN 219
Query: 583 VIMTEMAK 606
+ T K
Sbjct: 220 FVNTGFIK 227
>AF273056-1|AAM44459.1| 300|Homo sapiens CTCL tumor antigen
HD-CL-03 protein.
Length = 300
Score = 48.8 bits (111), Expect = 2e-05
Identities = 34/128 (26%), Positives = 53/128 (41%), Gaps = 3/128 (2%)
Frame = +1
Query: 232 WEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMI 411
+ +KV +G LVNNA V +KTF+VNV A ++ M
Sbjct: 101 YSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMT 160
Query: 412 ENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPY---GIRVNAINPT 582
+N HG IV ++S A ++ Y +SK A + + EL G++ + P
Sbjct: 161 KN-NHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPN 219
Query: 583 VIMTEMAK 606
+ T K
Sbjct: 220 FVNTGFIK 227
>AF126780-1|AAF06939.1| 300|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR2 protein.
Length = 300
Score = 48.8 bits (111), Expect = 2e-05
Identities = 34/128 (26%), Positives = 53/128 (41%), Gaps = 3/128 (2%)
Frame = +1
Query: 232 WEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMI 411
+ +KV +G LVNNA V +KTF+VNV A ++ M
Sbjct: 101 YSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMT 160
Query: 412 ENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPY---GIRVNAINPT 582
+N HG IV ++S A ++ Y +SK A + + EL G++ + P
Sbjct: 161 KN-NHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPN 219
Query: 583 VIMTEMAK 606
+ T K
Sbjct: 220 FVNTGFIK 227
>AY358473-1|AAQ88837.1| 331|Homo sapiens RDH13 protein.
Length = 331
Score = 48.4 bits (110), Expect = 3e-05
Identities = 49/205 (23%), Positives = 82/205 (40%), Gaps = 23/205 (11%)
Frame = +1
Query: 61 GKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPS------IDIVDVD 222
GK ++VT EL R G NI+ R E+ + ++ +D
Sbjct: 38 GKTVIVTGANTGIGKQTALELARRGGNIILACRDMEKCEAAAKDIRGETLNHHVNARHLD 97
Query: 223 IGDWEKTR----KVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQ 390
+ + R K++E D L+NNA V C + + F+ F VN ++
Sbjct: 98 LASLKSIREFAAKIIEEEERVDILINNAGVMRCPHWT--TEDGFEMQFGVNHLGHFLLTN 155
Query: 391 VVARKMIENKTHGAIVNISSQASKAALKDH-------------TIYSASKAALDALTRAM 531
++ K+ + I+N+SS A A D Y SK A+ T+ +
Sbjct: 156 LLLDKL-KASAPSRIINLSSLAHVAGHIDFDDLNWQTRKYNTKAAYCQSKLAIVLFTKEL 214
Query: 532 ALELGPYGIRVNAINPTVIMTEMAK 606
+ L G+ VNA++P V TE+ +
Sbjct: 215 SRRLQGSGVTVNALHPGVARTELGR 239
>AK075392-1|BAC11591.1| 331|Homo sapiens protein ( Homo sapiens
cDNA PSEC0082 fis, clone NT2RP2004966, highly similar to
Retinol dehydrogenase 13 (EC 1.1.1.-). ).
Length = 331
Score = 48.4 bits (110), Expect = 3e-05
Identities = 49/205 (23%), Positives = 82/205 (40%), Gaps = 23/205 (11%)
Frame = +1
Query: 61 GKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPS------IDIVDVD 222
GK ++VT EL R G NI+ R E+ + ++ +D
Sbjct: 38 GKTVIVTGANTGIGKQTALELARRGGNIILACRDMEKCEAAAKDIRGETLNHHVNARHLD 97
Query: 223 IGDWEKTR----KVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQ 390
+ + R K++E D L+NNA V C + + F+ F VN ++
Sbjct: 98 LASLKSIRVFAAKIIEEEERVDILINNAGVMRCPHWT--TEDGFEMQFGVNHLGHFLLTN 155
Query: 391 VVARKMIENKTHGAIVNISSQASKAALKDH-------------TIYSASKAALDALTRAM 531
++ K+ + I+N+SS A A D Y SK A+ T+ +
Sbjct: 156 LLLDKL-KASAPSRIINLSSLAHVAGHIDFDDLNWQTRKYNTKAAYCQSKLAIVLFTKEL 214
Query: 532 ALELGPYGIRVNAINPTVIMTEMAK 606
+ L G+ VNA++P V TE+ +
Sbjct: 215 SRRLQGSGVTVNALHPGVARTELGR 239
>BC112305-1|AAI12306.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 13 protein.
Length = 300
Score = 47.6 bits (108), Expect = 4e-05
Identities = 33/128 (25%), Positives = 54/128 (42%), Gaps = 3/128 (2%)
Frame = +1
Query: 232 WEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMI 411
+ +V + +G +VNNA L KTF+VN+ I++ + M+
Sbjct: 101 YRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWITKALLPSMM 160
Query: 412 ENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALE---LGPYGIRVNAINPT 582
E + HG IV ++S + Y +SK A R + E LG GI+ + + P
Sbjct: 161 E-RNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGIKTSCLCPV 219
Query: 583 VIMTEMAK 606
+ T K
Sbjct: 220 FVNTGFTK 227
>BC112303-1|AAI12304.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 13 protein.
Length = 300
Score = 47.6 bits (108), Expect = 4e-05
Identities = 33/128 (25%), Positives = 54/128 (42%), Gaps = 3/128 (2%)
Frame = +1
Query: 232 WEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMI 411
+ +V + +G +VNNA L KTF+VN+ I++ + M+
Sbjct: 101 YRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWITKALLPSMM 160
Query: 412 ENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALE---LGPYGIRVNAINPT 582
E + HG IV ++S + Y +SK A R + E LG GI+ + + P
Sbjct: 161 E-RNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGIKTSCLCPV 219
Query: 583 VIMTEMAK 606
+ T K
Sbjct: 220 FVNTGFTK 227
>AY358575-1|AAQ88938.1| 300|Homo sapiens NIIL497 protein.
Length = 300
Score = 47.6 bits (108), Expect = 4e-05
Identities = 33/128 (25%), Positives = 54/128 (42%), Gaps = 3/128 (2%)
Frame = +1
Query: 232 WEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMI 411
+ +V + +G +VNNA L KTF+VN+ I++ + M+
Sbjct: 101 YRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWITKALLPSMM 160
Query: 412 ENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALE---LGPYGIRVNAINPT 582
E + HG IV ++S + Y +SK A R + E LG GI+ + + P
Sbjct: 161 E-RNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGIKTSCLCPV 219
Query: 583 VIMTEMAK 606
+ T K
Sbjct: 220 FVNTGFTK 227
>AY268355-1|AAP42289.1| 300|Homo sapiens short-chain
dehydrogenase/reductase 9 protein.
Length = 300
Score = 47.6 bits (108), Expect = 4e-05
Identities = 33/128 (25%), Positives = 54/128 (42%), Gaps = 3/128 (2%)
Frame = +1
Query: 232 WEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMI 411
+ +V + +G +VNNA L KTF+VN+ I++ + M+
Sbjct: 101 YRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWITKALLPSMM 160
Query: 412 ENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALE---LGPYGIRVNAINPT 582
E + HG IV ++S + Y +SK A R + E LG GI+ + + P
Sbjct: 161 E-RNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGIKTSCLCPV 219
Query: 583 VIMTEMAK 606
+ T K
Sbjct: 220 FVNTGFTK 227
>AY186249-1|AAO72313.1| 300|Homo sapiens 17-beta hydroxysteroid
dehydrogenase protein.
Length = 300
Score = 47.6 bits (108), Expect = 4e-05
Identities = 33/128 (25%), Positives = 54/128 (42%), Gaps = 3/128 (2%)
Frame = +1
Query: 232 WEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMI 411
+ +V + +G +VNNA L KTF+VN+ I++ + M+
Sbjct: 101 YRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWITKALLPSMM 160
Query: 412 ENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALE---LGPYGIRVNAINPT 582
E + HG IV ++S + Y +SK A R + E LG GI+ + + P
Sbjct: 161 E-RNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGIKTSCLCPV 219
Query: 583 VIMTEMAK 606
+ T K
Sbjct: 220 FVNTGFTK 227
>AB073347-1|BAD38632.1| 300|Homo sapiens putative protein product
of HMFN0376 protein.
Length = 300
Score = 47.6 bits (108), Expect = 4e-05
Identities = 33/128 (25%), Positives = 54/128 (42%), Gaps = 3/128 (2%)
Frame = +1
Query: 232 WEKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMI 411
+ +V + +G +VNNA L KTF+VN+ I++ + M+
Sbjct: 101 YRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWITKALLPSMM 160
Query: 412 ENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALE---LGPYGIRVNAINPT 582
E + HG IV ++S + Y +SK A R + E LG GI+ + + P
Sbjct: 161 E-RNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGIKTSCLCPV 219
Query: 583 VIMTEMAK 606
+ T K
Sbjct: 220 FVNTGFTK 227
>L40802-1|AAC41917.1| 387|Homo sapiens 17-hydroxysteroid
dehydrogenase protein.
Length = 387
Score = 46.8 bits (106), Expect = 8e-05
Identities = 26/68 (38%), Positives = 39/68 (57%)
Frame = +1
Query: 418 KTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTE 597
K+ G +VN+SS A ++ Y +SKAA+ + M LEL +GI+V +I P +T
Sbjct: 209 KSKGRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTN 268
Query: 598 MAKVGWSD 621
+A G SD
Sbjct: 269 IA--GTSD 274
>L11708-1|AAA03562.1| 387|Homo sapiens 17 beta hydroxysteroid
dehydrogenase type 2 protein.
Length = 387
Score = 46.8 bits (106), Expect = 8e-05
Identities = 26/68 (38%), Positives = 39/68 (57%)
Frame = +1
Query: 418 KTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTE 597
K+ G +VN+SS A ++ Y +SKAA+ + M LEL +GI+V +I P +T
Sbjct: 209 KSKGRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTN 268
Query: 598 MAKVGWSD 621
+A G SD
Sbjct: 269 IA--GTSD 274
>BC059170-1|AAH59170.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 46.8 bits (106), Expect = 8e-05
Identities = 26/68 (38%), Positives = 39/68 (57%)
Frame = +1
Query: 418 KTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTE 597
K+ G +VN+SS A ++ Y +SKAA+ + M LEL +GI+V +I P +T
Sbjct: 209 KSKGRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTN 268
Query: 598 MAKVGWSD 621
+A G SD
Sbjct: 269 IA--GTSD 274
>BC009581-1|AAH09581.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 46.8 bits (106), Expect = 8e-05
Identities = 26/68 (38%), Positives = 39/68 (57%)
Frame = +1
Query: 418 KTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTE 597
K+ G +VN+SS A ++ Y +SKAA+ + M LEL +GI+V +I P +T
Sbjct: 209 KSKGRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTN 268
Query: 598 MAKVGWSD 621
+A G SD
Sbjct: 269 IA--GTSD 274
>AY325910-1|AAP78485.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 46.8 bits (106), Expect = 8e-05
Identities = 26/68 (38%), Positives = 39/68 (57%)
Frame = +1
Query: 418 KTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTE 597
K+ G +VN+SS A ++ Y +SKAA+ + M LEL +GI+V +I P +T
Sbjct: 209 KSKGRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTN 268
Query: 598 MAKVGWSD 621
+A G SD
Sbjct: 269 IA--GTSD 274
>AK223001-1|BAD96721.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 variant protein.
Length = 387
Score = 46.8 bits (106), Expect = 8e-05
Identities = 26/68 (38%), Positives = 39/68 (57%)
Frame = +1
Query: 418 KTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTE 597
K+ G +VN+SS A ++ Y +SKAA+ + M LEL +GI+V +I P +T
Sbjct: 209 KSKGRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTN 268
Query: 598 MAKVGWSD 621
+A G SD
Sbjct: 269 IA--GTSD 274
>X13440-1|CAA31792.1| 328|Homo sapiens protein ( Human mRNA for
17-beta-hydroxysteroid dehydrogenase (17-HSD) (EC
1.1.1.62). ).
Length = 328
Score = 46.4 bits (105), Expect = 1e-04
Identities = 32/127 (25%), Positives = 57/127 (44%), Gaps = 2/127 (1%)
Frame = +1
Query: 199 SIDIVDVDIGDWEKTRKVVESL--GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKA 372
S++ + +D+ D + E + G D LV NA + + P DVNV
Sbjct: 59 SLETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118
Query: 373 VLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPY 552
+ + Q M + + G ++ S L + +Y ASK AL+ L ++A+ L P+
Sbjct: 119 TVRMLQAFLPDM-KRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177
Query: 553 GIRVNAI 573
G+ ++ I
Sbjct: 178 GVHLSLI 184
>U34879-1|AAD05019.1| 328|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase protein.
Length = 328
Score = 46.4 bits (105), Expect = 1e-04
Identities = 32/127 (25%), Positives = 57/127 (44%), Gaps = 2/127 (1%)
Frame = +1
Query: 199 SIDIVDVDIGDWEKTRKVVESL--GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKA 372
S++ + +D+ D + E + G D LV NA + + P DVNV
Sbjct: 59 SLETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118
Query: 373 VLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPY 552
+ + Q M + + G ++ S L + +Y ASK AL+ L ++A+ L P+
Sbjct: 119 TVRMLQAFLPDM-KRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177
Query: 553 GIRVNAI 573
G+ ++ I
Sbjct: 178 GVHLSLI 184
>M84472-1|AAB16942.1| 328|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase protein.
Length = 328
Score = 46.4 bits (105), Expect = 1e-04
Identities = 32/127 (25%), Positives = 57/127 (44%), Gaps = 2/127 (1%)
Frame = +1
Query: 199 SIDIVDVDIGDWEKTRKVVESL--GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKA 372
S++ + +D+ D + E + G D LV NA + + P DVNV
Sbjct: 59 SLETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118
Query: 373 VLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPY 552
+ + Q M + + G ++ S L + +Y ASK AL+ L ++A+ L P+
Sbjct: 119 TVRMLQAFLPDM-KRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177
Query: 553 GIRVNAI 573
G+ ++ I
Sbjct: 178 GVHLSLI 184
>M36263-1|AAA35600.1| 328|Homo sapiens protein ( Human placental
17-beta-hydroxysteroid dehydrogenase mRNA, complete cds.
).
Length = 328
Score = 46.4 bits (105), Expect = 1e-04
Identities = 32/127 (25%), Positives = 57/127 (44%), Gaps = 2/127 (1%)
Frame = +1
Query: 199 SIDIVDVDIGDWEKTRKVVESL--GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKA 372
S++ + +D+ D + E + G D LV NA + + P DVNV
Sbjct: 59 SLETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118
Query: 373 VLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPY 552
+ + Q M + + G ++ S L + +Y ASK AL+ L ++A+ L P+
Sbjct: 119 TVRMLQAFLPDM-KRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177
Query: 553 GIRVNAI 573
G+ ++ I
Sbjct: 178 GVHLSLI 184
>M27138-1|AAB16941.1| 328|Homo sapiens protein ( Human estradiol 17
beta-dehydrogenase gene, complete cds. ).
Length = 328
Score = 46.4 bits (105), Expect = 1e-04
Identities = 32/127 (25%), Positives = 57/127 (44%), Gaps = 2/127 (1%)
Frame = +1
Query: 199 SIDIVDVDIGDWEKTRKVVESL--GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKA 372
S++ + +D+ D + E + G D LV NA + + P DVNV
Sbjct: 59 SLETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118
Query: 373 VLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPY 552
+ + Q M + + G ++ S L + +Y ASK AL+ L ++A+ L P+
Sbjct: 119 TVRMLQAFLPDM-KRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177
Query: 553 GIRVNAI 573
G+ ++ I
Sbjct: 178 GVHLSLI 184
>BC111935-1|AAI11936.1| 328|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 1 protein.
Length = 328
Score = 46.4 bits (105), Expect = 1e-04
Identities = 32/127 (25%), Positives = 57/127 (44%), Gaps = 2/127 (1%)
Frame = +1
Query: 199 SIDIVDVDIGDWEKTRKVVESL--GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKA 372
S++ + +D+ D + E + G D LV NA + + P DVNV
Sbjct: 59 SLETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118
Query: 373 VLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPY 552
+ + Q M + + G ++ S L + +Y ASK AL+ L ++A+ L P+
Sbjct: 119 TVRMLQAFLPDM-KRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177
Query: 553 GIRVNAI 573
G+ ++ I
Sbjct: 178 GVHLSLI 184
>BC104752-1|AAI04753.1| 328|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 1 protein.
Length = 328
Score = 46.4 bits (105), Expect = 1e-04
Identities = 32/127 (25%), Positives = 57/127 (44%), Gaps = 2/127 (1%)
Frame = +1
Query: 199 SIDIVDVDIGDWEKTRKVVESL--GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKA 372
S++ + +D+ D + E + G D LV NA + + P DVNV
Sbjct: 59 SLETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118
Query: 373 VLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPY 552
+ + Q M + + G ++ S L + +Y ASK AL+ L ++A+ L P+
Sbjct: 119 TVRMLQAFLPDM-KRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177
Query: 553 GIRVNAI 573
G+ ++ I
Sbjct: 178 GVHLSLI 184
>Z97054-7|CAI42652.1| 252|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 252
Score = 45.6 bits (103), Expect = 2e-04
Identities = 31/109 (28%), Positives = 50/109 (45%), Gaps = 11/109 (10%)
Frame = +1
Query: 265 GHFDALVNNAAVAVCEPFLDCSPS------NFDKTFDVNVKAVLNISQVVARKMIENKT- 423
G D VN A +AV + +F + DVN+ N+ ++VA +M +N+
Sbjct: 83 GRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPD 142
Query: 424 ----HGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGI 558
G I+N +S A+ YSASK + +T +A +L P G+
Sbjct: 143 QGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGL 191
>BC008708-1|AAH08708.1| 252|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 252
Score = 45.6 bits (103), Expect = 2e-04
Identities = 31/109 (28%), Positives = 50/109 (45%), Gaps = 11/109 (10%)
Frame = +1
Query: 265 GHFDALVNNAAVAVCEPFLDCSPS------NFDKTFDVNVKAVLNISQVVARKMIENKT- 423
G D VN A +AV + +F + DVN+ N+ ++VA +M +N+
Sbjct: 83 GRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPD 142
Query: 424 ----HGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGI 558
G I+N +S A+ YSASK + +T +A +L P G+
Sbjct: 143 QGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGL 191
>BC014057-1|AAH14057.1| 313|Homo sapiens DHRS1 protein protein.
Length = 313
Score = 44.8 bits (101), Expect = 3e-04
Identities = 54/204 (26%), Positives = 81/204 (39%), Gaps = 16/204 (7%)
Frame = +1
Query: 43 MEISFKGKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSI--DIVD 216
M G+ +VT +L +AGA + R L + E S+ V
Sbjct: 1 MAAPMNGQVCVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRVVAQEAQSLGGQCVP 60
Query: 217 V--DIGDWEKTRKVVESL-----GHFDALVNNAAVAVC-------EPFLDCSPSNFDKTF 354
V D + R + E + G D LVNNA V + F + S +D
Sbjct: 61 VVCDSSQESEVRSLFEQVDREQQGRLDVLVNNAYAGVQTILNTRNKAFWETPASMWDDIN 120
Query: 355 DVNVKAVLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMA 534
+V ++ S AR M+ G IV ISS S + + +Y KAA D L A
Sbjct: 121 NVGLRGHYFCSVYGARLMVP-AGQGLIVVISSPGSLQYMFN-VLYGVGKAACDKLAADCA 178
Query: 535 LELGPYGIRVNAINPTVIMTEMAK 606
EL +G+ ++ P ++ TE+ K
Sbjct: 179 HELRRHGVSCVSLWPGIVQTELLK 202
>BC008650-1|AAH08650.1| 300|Homo sapiens HSD17B11 protein protein.
Length = 300
Score = 44.8 bits (101), Expect = 3e-04
Identities = 32/118 (27%), Positives = 49/118 (41%), Gaps = 3/118 (2%)
Frame = +1
Query: 262 LGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVN 441
+G LVNNA V +KTF+VNV A ++ M +N HG IV
Sbjct: 111 IGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKN-NHGHIVT 169
Query: 442 ISSQASKAALKDHTIYSASKAALDALTRAMALELGPY---GIRVNAINPTVIMTEMAK 606
++S A ++ Y +SK A + + EL G++ + P + T K
Sbjct: 170 VASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNTGFIK 227
>X82460-1|CAA57843.1| 178|Homo sapiens 15-hydroxy prostaglandin
dehydrogenase protein.
Length = 178
Score = 44.4 bits (100), Expect = 4e-04
Identities = 31/99 (31%), Positives = 49/99 (49%), Gaps = 2/99 (2%)
Frame = +1
Query: 244 RKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENK- 420
RKVV+ G D LVNNA V + N++KT +N+ +V++ + + M +
Sbjct: 76 RKVVDHFGRLDILVNNAGVN--------NKKNWEKTLQINLVSVISGTYLGLDYMSKQNG 127
Query: 421 -THGAIVNISSQASKAALKDHTIYSASKAALDALTRAMA 534
G I+N+SS A + +Y ASK + TR+ A
Sbjct: 128 GEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAA 166
>CR457145-1|CAG33426.1| 157|Homo sapiens PECR protein.
Length = 157
Score = 44.4 bits (100), Expect = 4e-04
Identities = 35/101 (34%), Positives = 51/101 (50%), Gaps = 3/101 (2%)
Frame = +1
Query: 418 KTHG-AIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMT 594
K HG +IVNI +KA A++A + LT+++ALE GIR+N + P VI +
Sbjct: 2 KEHGGSIVNIIVP-TKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYS 60
Query: 595 EMAKVGWSDPIKA--NEMLSKIPLGRFGEISEVXNAVVFLL 711
+ A + ++ KIP R G EV + V FLL
Sbjct: 61 QTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLL 101
>AK027337-1|BAB55045.1| 179|Homo sapiens protein ( Homo sapiens
cDNA FLJ14431 fis, clone HEMBA1006521, weakly similar to
3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE (EC
1.1.1.100). ).
Length = 179
Score = 44.0 bits (99), Expect = 6e-04
Identities = 33/118 (27%), Positives = 53/118 (44%), Gaps = 1/118 (0%)
Frame = +1
Query: 229 DWEKTRKVVES-LGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARK 405
D + T + +E LG + LVN A + + + N+ + + R
Sbjct: 62 DVQNTFEEMEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRT 121
Query: 406 MIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINP 579
MI+ + G+IVN+ S ++YSASK L +RA+A E+ IRVN + P
Sbjct: 122 MIQQQG-GSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAP 178
>BC015943-1|AAH15943.1| 313|Homo sapiens DHRS1 protein protein.
Length = 313
Score = 43.2 bits (97), Expect = 0.001
Identities = 54/204 (26%), Positives = 80/204 (39%), Gaps = 16/204 (7%)
Frame = +1
Query: 43 MEISFKGKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSI--DIVD 216
M G+ +VT +L +AGA + R L + E S+ V
Sbjct: 1 MAAPMNGQACVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRVVAQEAQSLGGQCVP 60
Query: 217 V--DIGDWEKTRKVVESL-----GHFDALVNNAAVAVC-------EPFLDCSPSNFDKTF 354
V D + R + E + G D LVNNA V + F + S +D
Sbjct: 61 VVCDSSQESEVRSLFEQVDREQQGRLDVLVNNAYAGVQTILNTRNKAFWETPASMWDDIN 120
Query: 355 DVNVKAVLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMA 534
+V ++ S AR M+ G IV ISS S + + Y KAA D L A
Sbjct: 121 NVGLRGHYFCSVYGARLMVP-AGQGLIVVISSPGSLQYMFN-VPYGVGKAACDKLAADCA 178
Query: 535 LELGPYGIRVNAINPTVIMTEMAK 606
EL +G+ ++ P ++ TE+ K
Sbjct: 179 HELRRHGVSCVSLWPGIVQTELLK 202
>AK058159-1|BAB71694.1| 313|Homo sapiens protein ( Homo sapiens
cDNA FLJ25430 fis, clone TST06262. ).
Length = 313
Score = 42.7 bits (96), Expect = 0.001
Identities = 54/204 (26%), Positives = 80/204 (39%), Gaps = 16/204 (7%)
Frame = +1
Query: 43 MEISFKGKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSI--DIVD 216
M G+ +VT +L +AGA + R L + E S+ V
Sbjct: 1 MAAPMNGQVCVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRVVAQEAQSLGGQCVP 60
Query: 217 V--DIGDWEKTRKVVESL-----GHFDALVNNAAVAVC-------EPFLDCSPSNFDKTF 354
V D + R + E + G D LVNNA V + F + S +D
Sbjct: 61 VVCDSSQESEVRSLFEQVDREQQGRLDVLVNNAYAGVQTILNTRNKAFWETPASMWDDIN 120
Query: 355 DVNVKAVLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMA 534
+V ++ S AR M+ G IV ISS S + + Y KAA D L A
Sbjct: 121 NVGLRGHYFCSVYGARLMVP-AGQGLIVVISSPGSLQYMFN-VPYGVGKAACDKLAADCA 178
Query: 535 LELGPYGIRVNAINPTVIMTEMAK 606
EL +G+ ++ P ++ TE+ K
Sbjct: 179 HELRRHGVSCVSLWPGIVQTELLK 202
>AF418205-1|AAN32660.1| 313|Homo sapiens dehydrogenase/reductase
SDR family member 1 protein.
Length = 313
Score = 42.7 bits (96), Expect = 0.001
Identities = 54/204 (26%), Positives = 80/204 (39%), Gaps = 16/204 (7%)
Frame = +1
Query: 43 MEISFKGKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPSI--DIVD 216
M G+ +VT +L +AGA + R L + E S+ V
Sbjct: 1 MAAPMNGQVCVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRVVAQEAQSLGGQCVP 60
Query: 217 V--DIGDWEKTRKVVESL-----GHFDALVNNAAVAVC-------EPFLDCSPSNFDKTF 354
V D + R + E + G D LVNNA V + F + S +D
Sbjct: 61 VVCDSSQESEVRSLFEQVDREQQGRLDVLVNNAYAGVQTILNTRNKAFWETPASMWDDIN 120
Query: 355 DVNVKAVLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMA 534
+V ++ S AR M+ G IV ISS S + + Y KAA D L A
Sbjct: 121 NVGLRGHYFCSVYGARLMVP-AGQGLIVVISSPGSLQYMFN-VPYGVGKAACDKLAADCA 178
Query: 535 LELGPYGIRVNAINPTVIMTEMAK 606
EL +G+ ++ P ++ TE+ K
Sbjct: 179 HELRRHGVSCVSLWPGIVQTELLK 202
>U27317-1|AAB48544.1| 405|Homo sapiens 11 beta-hydroxysteroid
dehydrogenase 2 protein.
Length = 405
Score = 41.1 bits (92), Expect = 0.004
Identities = 31/110 (28%), Positives = 48/110 (43%), Gaps = 1/110 (0%)
Frame = +1
Query: 280 LVNNAAVAVCEPFLDCSP-SNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQA 456
LVNNA + SP + F +VN L +++ + + + G IV + S A
Sbjct: 164 LVNNAGHNEVVADAELSPVATFRSCMEVNFFGALELTKGLLPLL--RSSRGRIVTVGSPA 221
Query: 457 SKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMAK 606
Y SKAA+ L + EL P+G++V+ I P TE +
Sbjct: 222 GDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVKVSIIQPGCFKTESVR 271
>U26726-1|AAC50356.1| 405|Homo sapiens 11-beta-hydroxysteroid
dehydrogenase type 2 protein.
Length = 405
Score = 41.1 bits (92), Expect = 0.004
Identities = 31/110 (28%), Positives = 48/110 (43%), Gaps = 1/110 (0%)
Frame = +1
Query: 280 LVNNAAVAVCEPFLDCSP-SNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQA 456
LVNNA + SP + F +VN L +++ + + + G IV + S A
Sbjct: 164 LVNNAGHNEVVADAELSPVATFRSCMEVNFFGALELTKGLLPLL--RSSRGRIVTVGSPA 221
Query: 457 SKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMAK 606
Y SKAA+ L + EL P+G++V+ I P TE +
Sbjct: 222 GDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVKVSIIQPGCFKTESVR 271
>U14631-1|AAA91969.1| 405|Homo sapiens 11 beta-hydroxysteroid
dehydrogenase type II protein.
Length = 405
Score = 41.1 bits (92), Expect = 0.004
Identities = 31/110 (28%), Positives = 48/110 (43%), Gaps = 1/110 (0%)
Frame = +1
Query: 280 LVNNAAVAVCEPFLDCSP-SNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQA 456
LVNNA + SP + F +VN L +++ + + + G IV + S A
Sbjct: 164 LVNNAGHNEVVADAELSPVATFRSCMEVNFFGALELTKGLLPLL--RSSRGRIVTVGSPA 221
Query: 457 SKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMAK 606
Y SKAA+ L + EL P+G++V+ I P TE +
Sbjct: 222 GDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVKVSIIQPGCFKTESVR 271
>EF694683-1|ABS29267.1| 405|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 2 protein.
Length = 405
Score = 41.1 bits (92), Expect = 0.004
Identities = 31/110 (28%), Positives = 48/110 (43%), Gaps = 1/110 (0%)
Frame = +1
Query: 280 LVNNAAVAVCEPFLDCSP-SNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQA 456
LVNNA + SP + F +VN L +++ + + + G IV + S A
Sbjct: 164 LVNNAGHNEVVADAELSPVATFRSCMEVNFFGALELTKGLLPLL--RSSRGRIVTVGSPA 221
Query: 457 SKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMAK 606
Y SKAA+ L + EL P+G++V+ I P TE +
Sbjct: 222 GDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVKVSIIQPGCFKTESVR 271
>BC064536-1|AAH64536.1| 405|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 2 protein.
Length = 405
Score = 41.1 bits (92), Expect = 0.004
Identities = 31/110 (28%), Positives = 48/110 (43%), Gaps = 1/110 (0%)
Frame = +1
Query: 280 LVNNAAVAVCEPFLDCSP-SNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQA 456
LVNNA + SP + F +VN L +++ + + + G IV + S A
Sbjct: 164 LVNNAGHNEVVADAELSPVATFRSCMEVNFFGALELTKGLLPLL--RSSRGRIVTVGSPA 221
Query: 457 SKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMAK 606
Y SKAA+ L + EL P+G++V+ I P TE +
Sbjct: 222 GDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVKVSIIQPGCFKTESVR 271
>BC036780-1|AAH36780.1| 405|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 2 protein.
Length = 405
Score = 41.1 bits (92), Expect = 0.004
Identities = 31/110 (28%), Positives = 48/110 (43%), Gaps = 1/110 (0%)
Frame = +1
Query: 280 LVNNAAVAVCEPFLDCSP-SNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQA 456
LVNNA + SP + F +VN L +++ + + + G IV + S A
Sbjct: 164 LVNNAGHNEVVADAELSPVATFRSCMEVNFFGALELTKGLLPLL--RSSRGRIVTVGSPA 221
Query: 457 SKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMAK 606
Y SKAA+ L + EL P+G++V+ I P TE +
Sbjct: 222 GDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVKVSIIQPGCFKTESVR 271
>BC009881-1|AAH09881.1| 260|Homo sapiens retinol dehydrogenase 13
(all-trans/9-cis) protein.
Length = 260
Score = 40.7 bits (91), Expect = 0.005
Identities = 36/137 (26%), Positives = 59/137 (43%), Gaps = 13/137 (9%)
Frame = +1
Query: 235 EKTRKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIE 414
E K++E D L+NNA V C + + F+ F VN ++ ++ K+ +
Sbjct: 35 EFAAKIIEEEERVDILINNAGVMRCPHWT--TEDGFEMQFGVNHLGHFLLTNLLLDKL-K 91
Query: 415 NKTHGAIVNISSQASKAALKDH-------------TIYSASKAALDALTRAMALELGPYG 555
I+N+SS A A D Y SK A+ T+ ++ L G
Sbjct: 92 ASAPSRIINLSSLAHVAGHIDFDDLNWQTRKYNTKAAYCQSKLAIVLFTKELSRRLQGSG 151
Query: 556 IRVNAINPTVIMTEMAK 606
+ VNA++P V TE+ +
Sbjct: 152 VTVNALHPGVARTELGR 168
>BC019317-1|AAH19317.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 40.3 bits (90), Expect = 0.007
Identities = 35/144 (24%), Positives = 68/144 (47%), Gaps = 8/144 (5%)
Frame = +1
Query: 172 LESLQSEYPSIDIVDVDIGDWEKTRKVVE----SLGHFD----ALVNNAAVAVCEPFLDC 327
L+SL S+ + V +++ E+ KVVE SL + LVNNA ++
Sbjct: 99 LDSLNSD--RLRTVQLNVCSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFT 156
Query: 328 SPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAA 507
S + + +VN+ + +++ + + G +VNISS + A + Y +K
Sbjct: 157 SLETYKQVAEVNLWGTVRMTKSFLPLI--RRAKGRVVNISSMLGRMANPARSPYCITKFG 214
Query: 508 LDALTRAMALELGPYGIRVNAINP 579
++A + + E+ P G++V+ + P
Sbjct: 215 VEAFSDCLRYEMYPLGVKVSVVEP 238
>BC011964-1|AAH11964.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 40.3 bits (90), Expect = 0.007
Identities = 35/144 (24%), Positives = 68/144 (47%), Gaps = 8/144 (5%)
Frame = +1
Query: 172 LESLQSEYPSIDIVDVDIGDWEKTRKVVE----SLGHFD----ALVNNAAVAVCEPFLDC 327
L+SL S+ + V +++ E+ KVVE SL + LVNNA ++
Sbjct: 99 LDSLNSD--RLRTVQLNVCSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFT 156
Query: 328 SPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAA 507
S + + +VN+ + +++ + + G +VNISS + A + Y +K
Sbjct: 157 SLETYKQVAEVNLWGTVRMTKSFLPLI--RRAKGRVVNISSMLGRMANPARSPYCITKFG 214
Query: 508 LDALTRAMALELGPYGIRVNAINP 579
++A + + E+ P G++V+ + P
Sbjct: 215 VEAFSDCLRYEMYPLGVKVSVVEP 238
>BC005844-1|AAH05844.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 40.3 bits (90), Expect = 0.007
Identities = 35/144 (24%), Positives = 68/144 (47%), Gaps = 8/144 (5%)
Frame = +1
Query: 172 LESLQSEYPSIDIVDVDIGDWEKTRKVVE----SLGHFD----ALVNNAAVAVCEPFLDC 327
L+SL S+ + V +++ E+ KVVE SL + LVNNA ++
Sbjct: 99 LDSLNSD--RLRTVQLNVCSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFT 156
Query: 328 SPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAA 507
S + + +VN+ + +++ + + G +VNISS + A + Y +K
Sbjct: 157 SLETYKQVAEVNLWGTVRMTKSFLPLI--RRAKGRVVNISSMLGRMANPARSPYCITKFG 214
Query: 508 LDALTRAMALELGPYGIRVNAINP 579
++A + + E+ P G++V+ + P
Sbjct: 215 VEAFSDCLRYEMYPLGVKVSVVEP 238
>AK024022-1|BAB14782.1| 219|Homo sapiens protein ( Homo sapiens
cDNA FLJ13960 fis, clone Y79AA1001233, weakly similar to
ESTRADIOL 17 BETA-DEHYDROGENASE 1 (EC 1.1.1.62). ).
Length = 219
Score = 40.3 bits (90), Expect = 0.007
Identities = 25/95 (26%), Positives = 46/95 (48%)
Frame = +1
Query: 313 PFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQASKAALKDHTIYS 492
P S + FD N + + + V M + + G IV ISS + + +Y+
Sbjct: 6 PLEGLSLAAMQNVFDTNFFGAVRLVKAVLPGM-KRRRQGHIVVISSVMGLQGVIFNDVYA 64
Query: 493 ASKAALDALTRAMALELGPYGIRVNAINPTVIMTE 597
ASK AL+ ++A++L + I ++ + P ++TE
Sbjct: 65 ASKFALEGFFESLAIQLLQFNIFISLVEPGPVVTE 99
>M93107-1|AAA58352.1| 343|Homo sapiens (R)-3-hydroxybutyrate
dehydrogenase protein.
Length = 343
Score = 39.9 bits (89), Expect = 0.009
Identities = 23/100 (23%), Positives = 48/100 (48%)
Frame = +1
Query: 280 LVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNISSQAS 459
LVNNA ++ S + + +VN+ + +++ + + G +VNISS
Sbjct: 141 LVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTKSFLPLI--RRAKGRVVNISSMLG 198
Query: 460 KAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINP 579
+ A + Y +K ++A + + E+ P G++V+ + P
Sbjct: 199 RMANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEP 238
>M29037-1|AAB17014.1| 214|Homo sapiens 17 beta-hydroxysteroid
dehydrogenase protein.
Length = 214
Score = 39.5 bits (88), Expect = 0.012
Identities = 28/103 (27%), Positives = 48/103 (46%)
Frame = +1
Query: 265 GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTHGAIVNI 444
G D LV N + + P + + ++ DVNV + + Q M + G ++
Sbjct: 83 GRVDVLVCNTGLGLLGPLGEDAVAS---VLDVNVVGTVRVLQDFLPDM-KRPGSGRVLVT 138
Query: 445 SSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAI 573
S L + +Y ASK AL+ L ++A+ L P+G+ V+ I
Sbjct: 139 GSMGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHVSLI 181
>BC067131-1|AAH67131.1| 341|Homo sapiens retinol dehydrogenase 10
(all-trans) protein.
Length = 341
Score = 39.5 bits (88), Expect = 0.012
Identities = 32/121 (26%), Positives = 52/121 (42%), Gaps = 3/121 (2%)
Frame = +1
Query: 247 KVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTH 426
+V + +G LVNNA V L+C ++T VN A ++ M+E H
Sbjct: 131 RVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFWTTKAFLPTMLE-INH 189
Query: 427 GAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPY---GIRVNAINPTVIMTE 597
G IV ++S + Y ASK + +++ EL GI+ + P ++ T
Sbjct: 190 GHIVTVASSLGLFSTAGVEDYCASKFGVVGFHESLSHELKAAEKDGIKTTLVCPYLVDTG 249
Query: 598 M 600
M
Sbjct: 250 M 250
>AY358270-1|AAQ88637.1| 341|Homo sapiens RDH10 protein.
Length = 341
Score = 39.5 bits (88), Expect = 0.012
Identities = 32/121 (26%), Positives = 52/121 (42%), Gaps = 3/121 (2%)
Frame = +1
Query: 247 KVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTH 426
+V + +G LVNNA V L+C ++T VN A ++ M+E H
Sbjct: 131 RVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFWTTKAFLPTMLE-INH 189
Query: 427 GAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPY---GIRVNAINPTVIMTE 597
G IV ++S + Y ASK + +++ EL GI+ + P ++ T
Sbjct: 190 GHIVTVASSLGLFSTAGVEDYCASKFGVVGFHESLSHELKAAEKDGIKTTLVCPYLVDTG 249
Query: 598 M 600
M
Sbjct: 250 M 250
>AF456765-1|AAN64747.1| 341|Homo sapiens retinol dehydrogenase 10
protein.
Length = 341
Score = 39.5 bits (88), Expect = 0.012
Identities = 32/121 (26%), Positives = 52/121 (42%), Gaps = 3/121 (2%)
Frame = +1
Query: 247 KVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENKTH 426
+V + +G LVNNA V L+C ++T VN A ++ M+E H
Sbjct: 131 RVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFWTTKAFLPTMLE-INH 189
Query: 427 GAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPY---GIRVNAINPTVIMTE 597
G IV ++S + Y ASK + +++ EL GI+ + P ++ T
Sbjct: 190 GHIVTVASSLGLFSTAGVEDYCASKFGVVGFHESLSHELKAAEKDGIKTTLVCPYLVDTG 249
Query: 598 M 600
M
Sbjct: 250 M 250
>EF462915-1|ABO43035.1| 277|Homo sapiens carbonyl reductase 3
protein.
Length = 277
Score = 39.1 bits (87), Expect = 0.016
Identities = 32/105 (30%), Positives = 54/105 (51%), Gaps = 5/105 (4%)
Frame = +1
Query: 151 LSRTRSHLESLQSEYPSIDIVDVDIGDWEKTRKVVESL----GHFDALVNNAAVAVCEPF 318
++R ++ ++ LQ+E S +DI D + R + + L G + LVNNAAVA F
Sbjct: 40 VARGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLNVLVNNAAVA----F 95
Query: 319 LDCSPSNFDKTFDVNVKAVLNISQVVARKMIE-NKTHGAIVNISS 450
P FD ++ +K ++ + +++ K HG +VNISS
Sbjct: 96 KSDDPMPFDIKAEMTLKTNFFATRNMCNELLPIMKPHGRVVNISS 140
>CR541709-1|CAG46510.1| 277|Homo sapiens CBR3 protein.
Length = 277
Score = 39.1 bits (87), Expect = 0.016
Identities = 32/105 (30%), Positives = 54/105 (51%), Gaps = 5/105 (4%)
Frame = +1
Query: 151 LSRTRSHLESLQSEYPSIDIVDVDIGDWEKTRKVVESL----GHFDALVNNAAVAVCEPF 318
++R ++ ++ LQ+E S +DI D + R + + L G + LVNNAAVA F
Sbjct: 40 VARGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLNVLVNNAAVA----F 95
Query: 319 LDCSPSNFDKTFDVNVKAVLNISQVVARKMIE-NKTHGAIVNISS 450
P FD ++ +K ++ + +++ K HG +VNISS
Sbjct: 96 KSDDPMPFDIKAEMTLKTNFFATRNMCNELLPIMKPHGRVVNISS 140
>BC002812-1|AAH02812.1| 277|Homo sapiens carbonyl reductase 3
protein.
Length = 277
Score = 39.1 bits (87), Expect = 0.016
Identities = 32/105 (30%), Positives = 54/105 (51%), Gaps = 5/105 (4%)
Frame = +1
Query: 151 LSRTRSHLESLQSEYPSIDIVDVDIGDWEKTRKVVESL----GHFDALVNNAAVAVCEPF 318
++R ++ ++ LQ+E S +DI D + R + + L G + LVNNAAVA F
Sbjct: 40 VARGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLNVLVNNAAVA----F 95
Query: 319 LDCSPSNFDKTFDVNVKAVLNISQVVARKMIE-NKTHGAIVNISS 450
P FD ++ +K ++ + +++ K HG +VNISS
Sbjct: 96 KSDDPMPFDIKAEMTLKTNFFATRNMCNELLPIMKPHGRVVNISS 140
>BC002730-1|AAH02730.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 39.1 bits (87), Expect = 0.016
Identities = 37/132 (28%), Positives = 61/132 (46%), Gaps = 5/132 (3%)
Frame = +1
Query: 220 DIGDWEK---TRKVV-ESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNIS 387
D+G+ E+ T K V E +G LVNNAAV + +D K+ +N +
Sbjct: 96 DVGNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTT 155
Query: 388 QVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALE-LGPYGIRV 564
+ +M+E + +G IV ++S + +A+ Y SKA+ A ++ L L G+
Sbjct: 156 KAFLPRMLELQ-NGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSA 214
Query: 565 NAINPTVIMTEM 600
+ P TEM
Sbjct: 215 TTVLPFHTSTEM 226
>AP001725-1|BAA95547.1| 277|Homo sapiens carbonyl reductase (NADPH)
3, EC 1.1.1.284. protein.
Length = 277
Score = 39.1 bits (87), Expect = 0.016
Identities = 32/105 (30%), Positives = 54/105 (51%), Gaps = 5/105 (4%)
Frame = +1
Query: 151 LSRTRSHLESLQSEYPSIDIVDVDIGDWEKTRKVVESL----GHFDALVNNAAVAVCEPF 318
++R ++ ++ LQ+E S +DI D + R + + L G + LVNNAAVA F
Sbjct: 40 VARGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLNVLVNNAAVA----F 95
Query: 319 LDCSPSNFDKTFDVNVKAVLNISQVVARKMIE-NKTHGAIVNISS 450
P FD ++ +K ++ + +++ K HG +VNISS
Sbjct: 96 KSDDPMPFDIKAEMTLKTNFFATRNMCNELLPIMKPHGRVVNISS 140
>AP000689-1|BAA89425.1| 277|Homo sapiens carbonyl reductase 3
protein.
Length = 277
Score = 39.1 bits (87), Expect = 0.016
Identities = 32/105 (30%), Positives = 54/105 (51%), Gaps = 5/105 (4%)
Frame = +1
Query: 151 LSRTRSHLESLQSEYPSIDIVDVDIGDWEKTRKVVESL----GHFDALVNNAAVAVCEPF 318
++R ++ ++ LQ+E S +DI D + R + + L G + LVNNAAVA F
Sbjct: 40 VARGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLNVLVNNAAVA----F 95
Query: 319 LDCSPSNFDKTFDVNVKAVLNISQVVARKMIE-NKTHGAIVNISS 450
P FD ++ +K ++ + +++ K HG +VNISS
Sbjct: 96 KSDDPMPFDIKAEMTLKTNFFATRNMCNELLPIMKPHGRVVNISS 140
>AL645761-2|CAI15000.1| 147|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 147
Score = 39.1 bits (87), Expect = 0.016
Identities = 37/132 (28%), Positives = 61/132 (46%), Gaps = 5/132 (3%)
Frame = +1
Query: 220 DIGDWEK---TRKVV-ESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNIS 387
D+G+ E+ T K V E +G LVNNAAV + +D K+ +N +
Sbjct: 11 DVGNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTT 70
Query: 388 QVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALE-LGPYGIRV 564
+ +M+E + +G IV ++S + +A+ Y SKA+ A ++ L L G+
Sbjct: 71 KAFLPRMLELQ-NGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSA 129
Query: 565 NAINPTVIMTEM 600
+ P TEM
Sbjct: 130 TTVLPFHTSTEM 141
>AL645761-1|CAI14999.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 39.1 bits (87), Expect = 0.016
Identities = 37/132 (28%), Positives = 61/132 (46%), Gaps = 5/132 (3%)
Frame = +1
Query: 220 DIGDWEK---TRKVV-ESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNIS 387
D+G+ E+ T K V E +G LVNNAAV + +D K+ +N +
Sbjct: 96 DVGNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTT 155
Query: 388 QVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALE-LGPYGIRV 564
+ +M+E + +G IV ++S + +A+ Y SKA+ A ++ L L G+
Sbjct: 156 KAFLPRMLELQ-NGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSA 214
Query: 565 NAINPTVIMTEM 600
+ P TEM
Sbjct: 215 TTVLPFHTSTEM 226
>AL513016-1|CAH74172.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 39.1 bits (87), Expect = 0.016
Identities = 37/132 (28%), Positives = 61/132 (46%), Gaps = 5/132 (3%)
Frame = +1
Query: 220 DIGDWEK---TRKVV-ESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNIS 387
D+G+ E+ T K V E +G LVNNAAV + +D K+ +N +
Sbjct: 96 DVGNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTT 155
Query: 388 QVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALE-LGPYGIRV 564
+ +M+E + +G IV ++S + +A+ Y SKA+ A ++ L L G+
Sbjct: 156 KAFLPRMLELQ-NGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSA 214
Query: 565 NAINPTVIMTEM 600
+ P TEM
Sbjct: 215 TTVLPFHTSTEM 226
>AK223429-1|BAD97149.1| 277|Homo sapiens carbonyl reductase 3
variant protein.
Length = 277
Score = 39.1 bits (87), Expect = 0.016
Identities = 32/105 (30%), Positives = 54/105 (51%), Gaps = 5/105 (4%)
Frame = +1
Query: 151 LSRTRSHLESLQSEYPSIDIVDVDIGDWEKTRKVVESL----GHFDALVNNAAVAVCEPF 318
++R ++ ++ LQ+E S +DI D + R + + L G + LVNNAAVA F
Sbjct: 40 VARGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLNVLVNNAAVA----F 95
Query: 319 LDCSPSNFDKTFDVNVKAVLNISQVVARKMIE-NKTHGAIVNISS 450
P FD ++ +K ++ + +++ K HG +VNISS
Sbjct: 96 KSDDPMPFDIKAEMTLKTNFFATRNMCNELLPIMKPHGRVVNISS 140
>AK222593-1|BAD96313.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 variant protein.
Length = 302
Score = 39.1 bits (87), Expect = 0.016
Identities = 37/132 (28%), Positives = 61/132 (46%), Gaps = 5/132 (3%)
Frame = +1
Query: 220 DIGDWEK---TRKVV-ESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNIS 387
D+G+ E+ T K V E +G LVNNAAV + +D K+ +N +
Sbjct: 96 DVGNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTT 155
Query: 388 QVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALE-LGPYGIRV 564
+ +M+E + +G IV ++S + +A+ Y SKA+ A ++ L L G+
Sbjct: 156 KAFLPRMLELQ-NGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSA 214
Query: 565 NAINPTVIMTEM 600
+ P TEM
Sbjct: 215 TTVLPFHTSTEM 226
>AF179237-1|AAD55402.1| 302|Homo sapiens short-chain
dehydrogenase/reductase 1 protein.
Length = 302
Score = 39.1 bits (87), Expect = 0.016
Identities = 37/132 (28%), Positives = 61/132 (46%), Gaps = 5/132 (3%)
Frame = +1
Query: 220 DIGDWEK---TRKVV-ESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNIS 387
D+G+ E+ T K V E +G LVNNAAV + +D K+ +N +
Sbjct: 96 DVGNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTT 155
Query: 388 QVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALE-LGPYGIRV 564
+ +M+E + +G IV ++S + +A+ Y SKA+ A ++ L L G+
Sbjct: 156 KAFLPRMLELQ-NGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSA 214
Query: 565 NAINPTVIMTEM 600
+ P TEM
Sbjct: 215 TTVLPFHTSTEM 226
>AF061741-1|AAC63263.1| 302|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR1 protein.
Length = 302
Score = 39.1 bits (87), Expect = 0.016
Identities = 37/132 (28%), Positives = 61/132 (46%), Gaps = 5/132 (3%)
Frame = +1
Query: 220 DIGDWEK---TRKVV-ESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNIS 387
D+G+ E+ T K V E +G LVNNAAV + +D K+ +N +
Sbjct: 96 DVGNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTT 155
Query: 388 QVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALE-LGPYGIRV 564
+ +M+E + +G IV ++S + +A+ Y SKA+ A ++ L L G+
Sbjct: 156 KAFLPRMLELQ-NGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSA 214
Query: 565 NAINPTVIMTEM 600
+ P TEM
Sbjct: 215 TTVLPFHTSTEM 226
>AB124847-1|BAE45939.1| 277|Homo sapiens carbonyl reductase 3
protein.
Length = 277
Score = 39.1 bits (87), Expect = 0.016
Identities = 32/105 (30%), Positives = 54/105 (51%), Gaps = 5/105 (4%)
Frame = +1
Query: 151 LSRTRSHLESLQSEYPSIDIVDVDIGDWEKTRKVVESL----GHFDALVNNAAVAVCEPF 318
++R ++ ++ LQ+E S +DI D + R + + L G + LVNNAAVA F
Sbjct: 40 VARGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLNVLVNNAAVA----F 95
Query: 319 LDCSPSNFDKTFDVNVKAVLNISQVVARKMIE-NKTHGAIVNISS 450
P FD ++ +K ++ + +++ K HG +VNISS
Sbjct: 96 KSDDPMPFDIKAEMTLKTNFFATRNMCNELLPIMKPHGRVVNISS 140
>AB041012-1|BAD74062.1| 277|Homo sapiens NADPH-dependent carbonyl
reductase 3 protein.
Length = 277
Score = 39.1 bits (87), Expect = 0.016
Identities = 32/105 (30%), Positives = 54/105 (51%), Gaps = 5/105 (4%)
Frame = +1
Query: 151 LSRTRSHLESLQSEYPSIDIVDVDIGDWEKTRKVVESL----GHFDALVNNAAVAVCEPF 318
++R ++ ++ LQ+E S +DI D + R + + L G + LVNNAAVA F
Sbjct: 40 VARGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLNVLVNNAAVA----F 95
Query: 319 LDCSPSNFDKTFDVNVKAVLNISQVVARKMIE-NKTHGAIVNISS 450
P FD ++ +K ++ + +++ K HG +VNISS
Sbjct: 96 KSDDPMPFDIKAEMTLKTNFFATRNMCNELLPIMKPHGRVVNISS 140
>AB004854-1|BAA33500.1| 277|Homo sapiens carbonyl reductase 3
protein.
Length = 277
Score = 39.1 bits (87), Expect = 0.016
Identities = 32/105 (30%), Positives = 54/105 (51%), Gaps = 5/105 (4%)
Frame = +1
Query: 151 LSRTRSHLESLQSEYPSIDIVDVDIGDWEKTRKVVESL----GHFDALVNNAAVAVCEPF 318
++R ++ ++ LQ+E S +DI D + R + + L G + LVNNAAVA F
Sbjct: 40 VARGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLNVLVNNAAVA----F 95
Query: 319 LDCSPSNFDKTFDVNVKAVLNISQVVARKMIE-NKTHGAIVNISS 450
P FD ++ +K ++ + +++ K HG +VNISS
Sbjct: 96 KSDDPMPFDIKAEMTLKTNFFATRNMCNELLPIMKPHGRVVNISS 140
>AB003151-2|BAA34207.1| 277|Homo sapiens carbonyl reductase 3
protein.
Length = 277
Score = 39.1 bits (87), Expect = 0.016
Identities = 32/105 (30%), Positives = 54/105 (51%), Gaps = 5/105 (4%)
Frame = +1
Query: 151 LSRTRSHLESLQSEYPSIDIVDVDIGDWEKTRKVVESL----GHFDALVNNAAVAVCEPF 318
++R ++ ++ LQ+E S +DI D + R + + L G + LVNNAAVA F
Sbjct: 40 VARGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLNVLVNNAAVA----F 95
Query: 319 LDCSPSNFDKTFDVNVKAVLNISQVVARKMIE-NKTHGAIVNISS 450
P FD ++ +K ++ + +++ K HG +VNISS
Sbjct: 96 KSDDPMPFDIKAEMTLKTNFFATRNMCNELLPIMKPHGRVVNISS 140
>M76665-1|AAC31757.1| 292|Homo sapiens 11-beta-hydroxysteroid
dehydrogenase protein.
Length = 292
Score = 38.7 bits (86), Expect = 0.021
Identities = 42/179 (23%), Positives = 76/179 (42%), Gaps = 9/179 (5%)
Frame = +1
Query: 58 KGKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEY-----PSIDIVDVD 222
+GK ++VT L + GA++V +R++ L+ + S S +
Sbjct: 33 QGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGT 92
Query: 223 IGDWEKTRKVVES----LGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQ 390
+ D + V +G D L+ N + K+ +VN + + ++
Sbjct: 93 MEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLT- 151
Query: 391 VVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVN 567
V A M++ +++G+IV +SS A K A YSASK ALD ++ E + V+
Sbjct: 152 VAALPMLK-QSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVS 209
>BC012593-1|AAH12593.1| 292|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 1 protein.
Length = 292
Score = 38.7 bits (86), Expect = 0.021
Identities = 42/179 (23%), Positives = 76/179 (42%), Gaps = 9/179 (5%)
Frame = +1
Query: 58 KGKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEY-----PSIDIVDVD 222
+GK ++VT L + GA++V +R++ L+ + S S +
Sbjct: 33 QGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGT 92
Query: 223 IGDWEKTRKVVES----LGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQ 390
+ D + V +G D L+ N + K+ +VN + + ++
Sbjct: 93 MEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLT- 151
Query: 391 VVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVN 567
V A M++ +++G+IV +SS A K A YSASK ALD ++ E + V+
Sbjct: 152 VAALPMLK-QSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVS 209
>AY044084-1|AAK83653.1| 292|Homo sapiens 11-beta hydroxysteroid
dehydrogenase type 1 protein.
Length = 292
Score = 38.7 bits (86), Expect = 0.021
Identities = 42/179 (23%), Positives = 76/179 (42%), Gaps = 9/179 (5%)
Frame = +1
Query: 58 KGKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEY-----PSIDIVDVD 222
+GK ++VT L + GA++V +R++ L+ + S S +
Sbjct: 33 QGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGT 92
Query: 223 IGDWEKTRKVVES----LGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQ 390
+ D + V +G D L+ N + K+ +VN + + ++
Sbjct: 93 MEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLT- 151
Query: 391 VVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVN 567
V A M++ +++G+IV +SS A K A YSASK ALD ++ E + V+
Sbjct: 152 VAALPMLK-QSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVS 209
>AL031316-4|CAI20063.1| 292|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 1 protein.
Length = 292
Score = 38.7 bits (86), Expect = 0.021
Identities = 42/179 (23%), Positives = 76/179 (42%), Gaps = 9/179 (5%)
Frame = +1
Query: 58 KGKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEY-----PSIDIVDVD 222
+GK ++VT L + GA++V +R++ L+ + S S +
Sbjct: 33 QGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGT 92
Query: 223 IGDWEKTRKVVES----LGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQ 390
+ D + V +G D L+ N + K+ +VN + + ++
Sbjct: 93 MEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLT- 151
Query: 391 VVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVN 567
V A M++ +++G+IV +SS A K A YSASK ALD ++ E + V+
Sbjct: 152 VAALPMLK-QSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVS 209
>AL022398-8|CAA18541.2| 292|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 1 protein.
Length = 292
Score = 38.7 bits (86), Expect = 0.021
Identities = 42/179 (23%), Positives = 76/179 (42%), Gaps = 9/179 (5%)
Frame = +1
Query: 58 KGKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEY-----PSIDIVDVD 222
+GK ++VT L + GA++V +R++ L+ + S S +
Sbjct: 33 QGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGT 92
Query: 223 IGDWEKTRKVVES----LGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQ 390
+ D + V +G D L+ N + K+ +VN + + ++
Sbjct: 93 MEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLT- 151
Query: 391 VVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVN 567
V A M++ +++G+IV +SS A K A YSASK ALD ++ E + V+
Sbjct: 152 VAALPMLK-QSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVS 209
>M76231-1|AAA60314.1| 261|Homo sapiens sepiapterin reductase
protein.
Length = 261
Score = 38.3 bits (85), Expect = 0.028
Identities = 33/114 (28%), Positives = 58/114 (50%), Gaps = 4/114 (3%)
Frame = +1
Query: 280 LVNNAAVA--VCEPFLDCSPSN-FDKTFDVNVKAVLNISQVVARKMIENK-THGAIVNIS 447
L+NNA V + F+D S S + + +N+ ++L ++ V + ++ + +VNIS
Sbjct: 97 LINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNIS 156
Query: 448 SQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMAKV 609
S + K +Y A KAA D L + +ALE +RV P + T+M ++
Sbjct: 157 SLCALQPFKGWALYCAGKAARDMLFQVLALE--EPNVRVLNYAPGPLDTDMQQL 208
>BC017310-1|AAH17310.1| 261|Homo sapiens sepiapterin reductase
(7,8-dihydrobiopterin:NADP+ oxidoreductase) protein.
Length = 261
Score = 38.3 bits (85), Expect = 0.028
Identities = 33/114 (28%), Positives = 58/114 (50%), Gaps = 4/114 (3%)
Frame = +1
Query: 280 LVNNAAVA--VCEPFLDCSPSN-FDKTFDVNVKAVLNISQVVARKMIENK-THGAIVNIS 447
L+NNA V + F+D S S + + +N+ ++L ++ V + ++ + +VNIS
Sbjct: 97 LINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNIS 156
Query: 448 SQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMAKV 609
S + K +Y A KAA D L + +ALE +RV P + T+M ++
Sbjct: 157 SLCALQPFKGWALYCAGKAARDMLFQVLALE--EPNVRVLNYAPGPLDTDMQQL 208
>AK222942-1|BAD96662.1| 261|Homo sapiens sepiapterin reductase
(7,8-dihydrobiopterin:NADP+ oxidoreductase) variant
protein.
Length = 261
Score = 38.3 bits (85), Expect = 0.028
Identities = 33/114 (28%), Positives = 58/114 (50%), Gaps = 4/114 (3%)
Frame = +1
Query: 280 LVNNAAVA--VCEPFLDCSPSN-FDKTFDVNVKAVLNISQVVARKMIENK-THGAIVNIS 447
L+NNA V + F+D S S + + +N+ ++L ++ V + ++ + +VNIS
Sbjct: 97 LINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNIS 156
Query: 448 SQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRVNAINPTVIMTEMAKV 609
S + K +Y A KAA D L + +ALE +RV P + T+M ++
Sbjct: 157 SLCALQPFKGWALYCAGKAARDMLFQVLALE--EPNVRVLNYAPGPLDTDMQQL 208
>M62420-1|AAA17881.1| 277|Homo sapiens carbonyl reductase protein.
Length = 277
Score = 37.9 bits (84), Expect = 0.036
Identities = 34/113 (30%), Positives = 56/113 (49%), Gaps = 5/113 (4%)
Frame = +1
Query: 151 LSRTRSHLESLQSEYPSIDIVDVDIGDWEKTRKVVESL----GHFDALVNNAAVAVCEPF 318
++R ++ ++ LQ+E S +DI D + R + + L G D LVNNA +A F
Sbjct: 40 VTRGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLDVLVNNAGIA----F 95
Query: 319 LDCSPSNFDKTFDVNVKAVLNISQVVARKMIEN-KTHGAIVNISSQASKAALK 474
P+ F +V +K ++ V +++ K G +VN+SS S ALK
Sbjct: 96 KVADPTPFHIQAEVTMKTNFFGTRDVCTELLPLIKPQGRVVNVSSIMSVRALK 148
>J04056-1|AAA52070.1| 277|Homo sapiens carbonyl reductase protein.
Length = 277
Score = 37.9 bits (84), Expect = 0.036
Identities = 34/113 (30%), Positives = 56/113 (49%), Gaps = 5/113 (4%)
Frame = +1
Query: 151 LSRTRSHLESLQSEYPSIDIVDVDIGDWEKTRKVVESL----GHFDALVNNAAVAVCEPF 318
++R ++ ++ LQ+E S +DI D + R + + L G D LVNNA +A F
Sbjct: 40 VTRGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLDVLVNNAGIA----F 95
Query: 319 LDCSPSNFDKTFDVNVKAVLNISQVVARKMIEN-KTHGAIVNISSQASKAALK 474
P+ F +V +K ++ V +++ K G +VN+SS S ALK
Sbjct: 96 KVADPTPFHIQAEVTMKTNFFGTRDVCTELLPLIKPQGRVVNVSSIMSVRALK 148
>EF141836-1|ABK97430.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 37.9 bits (84), Expect = 0.036
Identities = 34/113 (30%), Positives = 56/113 (49%), Gaps = 5/113 (4%)
Frame = +1
Query: 151 LSRTRSHLESLQSEYPSIDIVDVDIGDWEKTRKVVESL----GHFDALVNNAAVAVCEPF 318
++R ++ ++ LQ+E S +DI D + R + + L G D LVNNA +A F
Sbjct: 40 VTRGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLDVLVNNAGIA----F 95
Query: 319 LDCSPSNFDKTFDVNVKAVLNISQVVARKMIEN-KTHGAIVNISSQASKAALK 474
P+ F +V +K ++ V +++ K G +VN+SS S ALK
Sbjct: 96 KVADPTPFHIQAEVTMKTNFFGTRDVCTELLPLIKPQGRVVNVSSIMSVRALK 148
>CR541708-1|CAG46509.1| 277|Homo sapiens CBR1 protein.
Length = 277
Score = 37.9 bits (84), Expect = 0.036
Identities = 34/113 (30%), Positives = 56/113 (49%), Gaps = 5/113 (4%)
Frame = +1
Query: 151 LSRTRSHLESLQSEYPSIDIVDVDIGDWEKTRKVVESL----GHFDALVNNAAVAVCEPF 318
++R ++ ++ LQ+E S +DI D + R + + L G D LVNNA +A F
Sbjct: 40 VTRGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLDVLVNNAGIA----F 95
Query: 319 LDCSPSNFDKTFDVNVKAVLNISQVVARKMIEN-KTHGAIVNISSQASKAALK 474
P+ F +V +K ++ V +++ K G +VN+SS S ALK
Sbjct: 96 KVADPTPFHIQAEVTMKTNFFGTRDVCTELLPLIKPQGRVVNVSSIMSVRALK 148
>BT019843-1|AAV38646.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 37.9 bits (84), Expect = 0.036
Identities = 34/113 (30%), Positives = 56/113 (49%), Gaps = 5/113 (4%)
Frame = +1
Query: 151 LSRTRSHLESLQSEYPSIDIVDVDIGDWEKTRKVVESL----GHFDALVNNAAVAVCEPF 318
++R ++ ++ LQ+E S +DI D + R + + L G D LVNNA +A F
Sbjct: 40 VTRGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLDVLVNNAGIA----F 95
Query: 319 LDCSPSNFDKTFDVNVKAVLNISQVVARKMIEN-KTHGAIVNISSQASKAALK 474
P+ F +V +K ++ V +++ K G +VN+SS S ALK
Sbjct: 96 KVADPTPFHIQAEVTMKTNFFGTRDVCTELLPLIKPQGRVVNVSSIMSVRALK 148
>BC015640-1|AAH15640.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 37.9 bits (84), Expect = 0.036
Identities = 34/113 (30%), Positives = 56/113 (49%), Gaps = 5/113 (4%)
Frame = +1
Query: 151 LSRTRSHLESLQSEYPSIDIVDVDIGDWEKTRKVVESL----GHFDALVNNAAVAVCEPF 318
++R ++ ++ LQ+E S +DI D + R + + L G D LVNNA +A F
Sbjct: 40 VTRGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLDVLVNNAGIA----F 95
Query: 319 LDCSPSNFDKTFDVNVKAVLNISQVVARKMIEN-KTHGAIVNISSQASKAALK 474
P+ F +V +K ++ V +++ K G +VN+SS S ALK
Sbjct: 96 KVADPTPFHIQAEVTMKTNFFGTRDVCTELLPLIKPQGRVVNVSSIMSVRALK 148
>BC002511-1|AAH02511.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 37.9 bits (84), Expect = 0.036
Identities = 34/113 (30%), Positives = 56/113 (49%), Gaps = 5/113 (4%)
Frame = +1
Query: 151 LSRTRSHLESLQSEYPSIDIVDVDIGDWEKTRKVVESL----GHFDALVNNAAVAVCEPF 318
++R ++ ++ LQ+E S +DI D + R + + L G D LVNNA +A F
Sbjct: 40 VTRGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLDVLVNNAGIA----F 95
Query: 319 LDCSPSNFDKTFDVNVKAVLNISQVVARKMIEN-KTHGAIVNISSQASKAALK 474
P+ F +V +K ++ V +++ K G +VN+SS S ALK
Sbjct: 96 KVADPTPFHIQAEVTMKTNFFGTRDVCTELLPLIKPQGRVVNVSSIMSVRALK 148
>AP001724-1|BAA95508.1| 277|Homo sapiens carbonyl reductase
(NAPDH)1, EC 1.1.1.184 protein.
Length = 277
Score = 37.9 bits (84), Expect = 0.036
Identities = 34/113 (30%), Positives = 56/113 (49%), Gaps = 5/113 (4%)
Frame = +1
Query: 151 LSRTRSHLESLQSEYPSIDIVDVDIGDWEKTRKVVESL----GHFDALVNNAAVAVCEPF 318
++R ++ ++ LQ+E S +DI D + R + + L G D LVNNA +A F
Sbjct: 40 VTRGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLDVLVNNAGIA----F 95
Query: 319 LDCSPSNFDKTFDVNVKAVLNISQVVARKMIEN-KTHGAIVNISSQASKAALK 474
P+ F +V +K ++ V +++ K G +VN+SS S ALK
Sbjct: 96 KVADPTPFHIQAEVTMKTNFFGTRDVCTELLPLIKPQGRVVNVSSIMSVRALK 148
>AP000688-1|BAA89424.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 37.9 bits (84), Expect = 0.036
Identities = 34/113 (30%), Positives = 56/113 (49%), Gaps = 5/113 (4%)
Frame = +1
Query: 151 LSRTRSHLESLQSEYPSIDIVDVDIGDWEKTRKVVESL----GHFDALVNNAAVAVCEPF 318
++R ++ ++ LQ+E S +DI D + R + + L G D LVNNA +A F
Sbjct: 40 VTRGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLDVLVNNAGIA----F 95
Query: 319 LDCSPSNFDKTFDVNVKAVLNISQVVARKMIEN-KTHGAIVNISSQASKAALK 474
P+ F +V +K ++ V +++ K G +VN+SS S ALK
Sbjct: 96 KVADPTPFHIQAEVTMKTNFFGTRDVCTELLPLIKPQGRVVNVSSIMSVRALK 148
>AB124848-1|BAE45940.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 37.9 bits (84), Expect = 0.036
Identities = 34/113 (30%), Positives = 56/113 (49%), Gaps = 5/113 (4%)
Frame = +1
Query: 151 LSRTRSHLESLQSEYPSIDIVDVDIGDWEKTRKVVESL----GHFDALVNNAAVAVCEPF 318
++R ++ ++ LQ+E S +DI D + R + + L G D LVNNA +A F
Sbjct: 40 VTRGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLDVLVNNAGIA----F 95
Query: 319 LDCSPSNFDKTFDVNVKAVLNISQVVARKMIEN-KTHGAIVNISSQASKAALK 474
P+ F +V +K ++ V +++ K G +VN+SS S ALK
Sbjct: 96 KVADPTPFHIQAEVTMKTNFFGTRDVCTELLPLIKPQGRVVNVSSIMSVRALK 148
>AB003151-1|BAA33498.1| 277|Homo sapiens carbonyl reductase
protein.
Length = 277
Score = 37.9 bits (84), Expect = 0.036
Identities = 34/113 (30%), Positives = 56/113 (49%), Gaps = 5/113 (4%)
Frame = +1
Query: 151 LSRTRSHLESLQSEYPSIDIVDVDIGDWEKTRKVVESL----GHFDALVNNAAVAVCEPF 318
++R ++ ++ LQ+E S +DI D + R + + L G D LVNNA +A F
Sbjct: 40 VTRGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLDVLVNNAGIA----F 95
Query: 319 LDCSPSNFDKTFDVNVKAVLNISQVVARKMIEN-KTHGAIVNISSQASKAALK 474
P+ F +V +K ++ V +++ K G +VN+SS S ALK
Sbjct: 96 KVADPTPFHIQAEVTMKTNFFGTRDVCTELLPLIKPQGRVVNVSSIMSVRALK 148
>AC092630-1|AAY15035.1| 198|Homo sapiens unknown protein.
Length = 198
Score = 37.5 bits (83), Expect = 0.048
Identities = 28/91 (30%), Positives = 48/91 (52%), Gaps = 4/91 (4%)
Frame = +1
Query: 280 LVNNAAVA--VCEPFLDCSPSN-FDKTFDVNVKAVLNISQVVARKMIENK-THGAIVNIS 447
L+NNA V + F+D S S + + +N+ ++L ++ V + ++ + +VNIS
Sbjct: 97 LINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNIS 156
Query: 448 SQASKAALKDHTIYSASKAALDALTRAMALE 540
S + K +Y A KAA D L + +ALE
Sbjct: 157 SLCALQPFKGWALYCAGKAARDMLFQVLALE 187
>AB017547-1|BAA34534.1| 198|Homo sapiens sepiapterin reductase
protein.
Length = 198
Score = 37.5 bits (83), Expect = 0.048
Identities = 28/91 (30%), Positives = 48/91 (52%), Gaps = 4/91 (4%)
Frame = +1
Query: 280 LVNNAAVA--VCEPFLDCSPSN-FDKTFDVNVKAVLNISQVVARKMIENK-THGAIVNIS 447
L+NNA V + F+D S S + + +N+ ++L ++ V + ++ + +VNIS
Sbjct: 97 LINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNIS 156
Query: 448 SQASKAALKDHTIYSASKAALDALTRAMALE 540
S + K +Y A KAA D L + +ALE
Sbjct: 157 SLCALQPFKGWALYCAGKAARDMLFQVLALE 187
>AY313894-1|AAP83166.1| 315|Homo sapiens short-chain
dehydrogenase/reductase 10e protein.
Length = 315
Score = 35.9 bits (79), Expect = 0.15
Identities = 40/180 (22%), Positives = 69/180 (38%), Gaps = 9/180 (5%)
Frame = +1
Query: 52 SFKGKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEY-----PSIDIVD 216
S +G +L+T R G+++V + T + L+ + P + +
Sbjct: 26 SLQGARVLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIA 85
Query: 217 VDIGDWEKTRKVVE----SLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNI 384
D+ E VV+ LG D LV N SP VN + + +
Sbjct: 86 ADMASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQL 145
Query: 385 SQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRV 564
+ + ++K G++V +SS + T YSA+K ALD ++ EL + V
Sbjct: 146 TSRALPSLTDSK--GSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 203
>AY268352-1|AAP42286.1| 286|Homo sapiens short-chain
dehydrogenase/reductase 10b protein.
Length = 286
Score = 35.9 bits (79), Expect = 0.15
Identities = 40/180 (22%), Positives = 69/180 (38%), Gaps = 9/180 (5%)
Frame = +1
Query: 52 SFKGKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEY-----PSIDIVD 216
S +G +L+T R G+++V + T + L+ + P + +
Sbjct: 26 SLQGARVLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIA 85
Query: 217 VDIGDWEKTRKVVE----SLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNI 384
D+ E VV+ LG D LV N SP VN + + +
Sbjct: 86 ADMASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQL 145
Query: 385 SQVVARKMIENKTHGAIVNISSQASKAALKDHTIYSASKAALDALTRAMALELGPYGIRV 564
+ + ++K G++V +SS + T YSA+K ALD ++ EL + V
Sbjct: 146 TSRALPSLTDSK--GSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 203
>U63296-1|AAB53034.1| 143|Homo sapiens 15-hydroxyprostaglandin
dehydrogenase protein.
Length = 143
Score = 33.5 bits (73), Expect = 0.78
Identities = 24/74 (32%), Positives = 39/74 (52%), Gaps = 2/74 (2%)
Frame = +1
Query: 244 RKVVESLGHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNISQVVARKMIENK- 420
RKVV+ G D LVNNA V + N++KT +N+ +V++ + + M +
Sbjct: 76 RKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVISGTYLGLDYMSKQNG 127
Query: 421 -THGAIVNISSQAS 459
G I+N+SS A+
Sbjct: 128 GEGGIIINMSSLAA 141
>AF069291-3|AAC62233.1| 188|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 188
Score = 33.1 bits (72), Expect = 1.0
Identities = 28/130 (21%), Positives = 52/130 (40%), Gaps = 9/130 (6%)
Frame = +1
Query: 52 SFKGKXILVTXXXXXXXXXXXXELWRAGANIVALSRTRSHLESLQSEYPS-----IDIVD 216
SF+GK +T L GA V SR L++ + S + +
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQ 115
Query: 217 VDIGDWEKTRKVVESL----GHFDALVNNAAVAVCEPFLDCSPSNFDKTFDVNVKAVLNI 384
D+ D + + V L GH + ++NNAA P SP+ + D+ + +
Sbjct: 116 CDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAFV 175
Query: 385 SQVVARKMIE 414
+ + +++I+
Sbjct: 176 TLEIGKQLIK 185
>U29344-1|AAA73576.1| 2509|Homo sapiens fatty acid synthase protein.
Length = 2509
Score = 30.3 bits (65), Expect = 7.3
Identities = 16/53 (30%), Positives = 26/53 (49%)
Frame = +1
Query: 145 VALSRTRSHLESLQSEYPSIDIVDVDIGDWEKTRKVVESLGHFDALVNNAAVA 303
++ + T H ++L++ + DV G W+ +LG D LV N AVA
Sbjct: 1268 LSYTATDRHPQALEAAQAELQQHDVAQGQWDPADPAPSALGSADLLVCNCAVA 1320
>U26644-1|AAC50259.1| 2504|Homo sapiens fas protein.
Length = 2504
Score = 30.3 bits (65), Expect = 7.3
Identities = 16/53 (30%), Positives = 26/53 (49%)
Frame = +1
Query: 145 VALSRTRSHLESLQSEYPSIDIVDVDIGDWEKTRKVVESLGHFDALVNNAAVA 303
++ + T H ++L++ + DV G W+ +LG D LV N AVA
Sbjct: 1266 LSYTATDRHPQALEAAQAELQQHDVAQGQWDPADPAPSALGSADLLVCNCAVA 1318
>BC063242-1|AAH63242.1| 2511|Homo sapiens fatty acid synthase protein.
Length = 2511
Score = 30.3 bits (65), Expect = 7.3
Identities = 16/53 (30%), Positives = 26/53 (49%)
Frame = +1
Query: 145 VALSRTRSHLESLQSEYPSIDIVDVDIGDWEKTRKVVESLGHFDALVNNAAVA 303
++ + T H ++L++ + DV G W+ +LG D LV N AVA
Sbjct: 1268 LSYTATDRHPQALEAAQAELQQHDVAQGQWDPADPAPSALGSADLLVCNCAVA 1320
>BC014631-1|AAH14631.1| 774|Homo sapiens FASN protein protein.
Length = 774
Score = 30.3 bits (65), Expect = 7.3
Identities = 16/53 (30%), Positives = 26/53 (49%)
Frame = +1
Query: 145 VALSRTRSHLESLQSEYPSIDIVDVDIGDWEKTRKVVESLGHFDALVNNAAVA 303
++ + T H ++L++ + DV G W+ +LG D LV N AVA
Sbjct: 174 LSYTATDRHPQALEAAQAELQQHDVAQGQWDPADPAPSALGSADLLVCNCAVA 226
>AY451392-1|AAS09886.1| 2511|Homo sapiens fatty acid synthase protein.
Length = 2511
Score = 30.3 bits (65), Expect = 7.3
Identities = 16/53 (30%), Positives = 26/53 (49%)
Frame = +1
Query: 145 VALSRTRSHLESLQSEYPSIDIVDVDIGDWEKTRKVVESLGHFDALVNNAAVA 303
++ + T H ++L++ + DV G W+ +LG D LV N AVA
Sbjct: 1268 LSYTATDRHPQALEAAQAELQQHDVAQGQWDPADPAPSALGSADLLVCNCAVA 1320
>AB209988-1|BAE06070.1| 2548|Homo sapiens FASN variant protein
protein.
Length = 2548
Score = 30.3 bits (65), Expect = 7.3
Identities = 16/53 (30%), Positives = 26/53 (49%)
Frame = +1
Query: 145 VALSRTRSHLESLQSEYPSIDIVDVDIGDWEKTRKVVESLGHFDALVNNAAVA 303
++ + T H ++L++ + DV G W+ +LG D LV N AVA
Sbjct: 1305 LSYTATDRHPQALEAAQAELQQHDVAQGQWDPADPAPSALGSADLLVCNCAVA 1357
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 90,285,716
Number of Sequences: 237096
Number of extensions: 1590665
Number of successful extensions: 4300
Number of sequences better than 10.0: 212
Number of HSP's better than 10.0 without gapping: 4053
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4228
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8511181328
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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