Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P04_F_E13
(798 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Z75048-1|CAA99340.1| 445|Homo sapiens homogentisate 1,2-dioxyge... 390 e-108
U63008-1|AAB16836.1| 445|Homo sapiens homogentisate dioxygenase... 390 e-108
BC071757-1|AAH71757.1| 445|Homo sapiens homogentisate 1,2-dioxy... 390 e-108
AF045167-1|AAC02698.1| 445|Homo sapiens homogentisate 1,2-dioxy... 390 e-108
AF000573-1|AAC51650.1| 445|Homo sapiens homogentisate 1,2-dioxy... 390 e-108
BC020792-1|AAH20792.1| 329|Homo sapiens homogentisate 1,2-dioxy... 306 6e-83
BC012775-1|AAH12775.3| 268|Homo sapiens chromosome 19 open read... 31 4.8
>Z75048-1|CAA99340.1| 445|Homo sapiens homogentisate
1,2-dioxygenase protein.
Length = 445
Score = 390 bits (959), Expect = e-108
Identities = 176/255 (69%), Positives = 206/255 (80%), Gaps = 3/255 (1%)
Frame = +2
Query: 41 RWLPFDIP--SDESVDFVTGLHTVCGAGDPRSRHGIAIHVYLCNASMDKSAFYSSDGDFL 214
RW PF+IP S + VDFV+GLHT+CGAGD +S +G+AIH++LCN SM+ FY+SDGDFL
Sbjct: 96 RWKPFEIPKASQKKVDFVSGLHTLCGAGDIKSNNGLAIHIFLCNTSMENRCFYNSDGDFL 155
Query: 215 IVPQQGKLKITTEFGLMEVAPNEIAVIQLGMRFAVFVEGPTRGYILEVFDGHFKLPDLGP 394
IVPQ+G L I TEFG M V PNEI VIQ GMRF++ V TRGYILEV+ HF+LPDLGP
Sbjct: 156 IVPQKGNLLIYTEFGKMLVQPNEICVIQRGMRFSIDVFEETRGYILEVYGVHFELPDLGP 215
Query: 395 IGANGLANPRDFLTPVAHYVDEETP-GFQIFNKYQGFLFVAEQNHNPFDVVAWHGNYVPY 571
IGANGLANPRDFL P+A Y D + P G+ + NKYQG LF A+Q+ +PF+VVAWHGNY PY
Sbjct: 216 IGANGLANPRDFLIPIAWYEDRQVPGGYTVINKYQGKLFAAKQDVSPFNVVAWHGNYTPY 275
Query: 572 KYDLNNFMVINAVLYDHCDPSIFTVLTCPSAKPGIAIADFVIFPPXWSVQEHTFRPPYYH 751
KY+L NFMVIN+V +DH DPSIFTVLT S +PG+AIADFVIFPP W V + TFRPPYYH
Sbjct: 276 KYNLKNFMVINSVAFDHADPSIFTVLTAKSVRPGVAIADFVIFPPRWGVADKTFRPPYYH 335
Query: 752 RNCMSEFMGLILGSY 796
RNCMSEFMGLI G Y
Sbjct: 336 RNCMSEFMGLIRGHY 350
>U63008-1|AAB16836.1| 445|Homo sapiens homogentisate dioxygenase
protein.
Length = 445
Score = 390 bits (959), Expect = e-108
Identities = 176/255 (69%), Positives = 206/255 (80%), Gaps = 3/255 (1%)
Frame = +2
Query: 41 RWLPFDIP--SDESVDFVTGLHTVCGAGDPRSRHGIAIHVYLCNASMDKSAFYSSDGDFL 214
RW PF+IP S + VDFV+GLHT+CGAGD +S +G+AIH++LCN SM+ FY+SDGDFL
Sbjct: 96 RWKPFEIPKASQKKVDFVSGLHTLCGAGDIKSNNGLAIHIFLCNTSMENRCFYNSDGDFL 155
Query: 215 IVPQQGKLKITTEFGLMEVAPNEIAVIQLGMRFAVFVEGPTRGYILEVFDGHFKLPDLGP 394
IVPQ+G L I TEFG M V PNEI VIQ GMRF++ V TRGYILEV+ HF+LPDLGP
Sbjct: 156 IVPQKGNLLIYTEFGKMLVQPNEICVIQRGMRFSIDVFEETRGYILEVYGVHFELPDLGP 215
Query: 395 IGANGLANPRDFLTPVAHYVDEETP-GFQIFNKYQGFLFVAEQNHNPFDVVAWHGNYVPY 571
IGANGLANPRDFL P+A Y D + P G+ + NKYQG LF A+Q+ +PF+VVAWHGNY PY
Sbjct: 216 IGANGLANPRDFLIPIAWYEDRQVPGGYTVINKYQGKLFAAKQDVSPFNVVAWHGNYTPY 275
Query: 572 KYDLNNFMVINAVLYDHCDPSIFTVLTCPSAKPGIAIADFVIFPPXWSVQEHTFRPPYYH 751
KY+L NFMVIN+V +DH DPSIFTVLT S +PG+AIADFVIFPP W V + TFRPPYYH
Sbjct: 276 KYNLKNFMVINSVAFDHADPSIFTVLTAKSVRPGVAIADFVIFPPRWGVADKTFRPPYYH 335
Query: 752 RNCMSEFMGLILGSY 796
RNCMSEFMGLI G Y
Sbjct: 336 RNCMSEFMGLIRGHY 350
>BC071757-1|AAH71757.1| 445|Homo sapiens homogentisate
1,2-dioxygenase (homogentisate oxidase) protein.
Length = 445
Score = 390 bits (959), Expect = e-108
Identities = 176/255 (69%), Positives = 206/255 (80%), Gaps = 3/255 (1%)
Frame = +2
Query: 41 RWLPFDIP--SDESVDFVTGLHTVCGAGDPRSRHGIAIHVYLCNASMDKSAFYSSDGDFL 214
RW PF+IP S + VDFV+GLHT+CGAGD +S +G+AIH++LCN SM+ FY+SDGDFL
Sbjct: 96 RWKPFEIPKASQKKVDFVSGLHTLCGAGDIKSNNGLAIHIFLCNTSMENRCFYNSDGDFL 155
Query: 215 IVPQQGKLKITTEFGLMEVAPNEIAVIQLGMRFAVFVEGPTRGYILEVFDGHFKLPDLGP 394
IVPQ+G L I TEFG M V PNEI VIQ GMRF++ V TRGYILEV+ HF+LPDLGP
Sbjct: 156 IVPQKGNLLIYTEFGKMLVQPNEICVIQRGMRFSIDVFEETRGYILEVYGVHFELPDLGP 215
Query: 395 IGANGLANPRDFLTPVAHYVDEETP-GFQIFNKYQGFLFVAEQNHNPFDVVAWHGNYVPY 571
IGANGLANPRDFL P+A Y D + P G+ + NKYQG LF A+Q+ +PF+VVAWHGNY PY
Sbjct: 216 IGANGLANPRDFLIPIAWYEDRQVPGGYTVINKYQGKLFAAKQDVSPFNVVAWHGNYTPY 275
Query: 572 KYDLNNFMVINAVLYDHCDPSIFTVLTCPSAKPGIAIADFVIFPPXWSVQEHTFRPPYYH 751
KY+L NFMVIN+V +DH DPSIFTVLT S +PG+AIADFVIFPP W V + TFRPPYYH
Sbjct: 276 KYNLKNFMVINSVAFDHADPSIFTVLTAKSVRPGVAIADFVIFPPRWGVADKTFRPPYYH 335
Query: 752 RNCMSEFMGLILGSY 796
RNCMSEFMGLI G Y
Sbjct: 336 RNCMSEFMGLIRGHY 350
>AF045167-1|AAC02698.1| 445|Homo sapiens homogentisate
1,2-dioxygenase protein.
Length = 445
Score = 390 bits (959), Expect = e-108
Identities = 176/255 (69%), Positives = 206/255 (80%), Gaps = 3/255 (1%)
Frame = +2
Query: 41 RWLPFDIP--SDESVDFVTGLHTVCGAGDPRSRHGIAIHVYLCNASMDKSAFYSSDGDFL 214
RW PF+IP S + VDFV+GLHT+CGAGD +S +G+AIH++LCN SM+ FY+SDGDFL
Sbjct: 96 RWKPFEIPKASQKKVDFVSGLHTLCGAGDIKSNNGLAIHIFLCNTSMENRCFYNSDGDFL 155
Query: 215 IVPQQGKLKITTEFGLMEVAPNEIAVIQLGMRFAVFVEGPTRGYILEVFDGHFKLPDLGP 394
IVPQ+G L I TEFG M V PNEI VIQ GMRF++ V TRGYILEV+ HF+LPDLGP
Sbjct: 156 IVPQKGNLLIYTEFGKMLVQPNEICVIQRGMRFSIDVFEETRGYILEVYGVHFELPDLGP 215
Query: 395 IGANGLANPRDFLTPVAHYVDEETP-GFQIFNKYQGFLFVAEQNHNPFDVVAWHGNYVPY 571
IGANGLANPRDFL P+A Y D + P G+ + NKYQG LF A+Q+ +PF+VVAWHGNY PY
Sbjct: 216 IGANGLANPRDFLIPIAWYEDRQVPGGYTVINKYQGKLFAAKQDVSPFNVVAWHGNYTPY 275
Query: 572 KYDLNNFMVINAVLYDHCDPSIFTVLTCPSAKPGIAIADFVIFPPXWSVQEHTFRPPYYH 751
KY+L NFMVIN+V +DH DPSIFTVLT S +PG+AIADFVIFPP W V + TFRPPYYH
Sbjct: 276 KYNLKNFMVINSVAFDHADPSIFTVLTAKSVRPGVAIADFVIFPPRWGVADKTFRPPYYH 335
Query: 752 RNCMSEFMGLILGSY 796
RNCMSEFMGLI G Y
Sbjct: 336 RNCMSEFMGLIRGHY 350
>AF000573-1|AAC51650.1| 445|Homo sapiens homogentisate
1,2-dioxygenase protein.
Length = 445
Score = 390 bits (959), Expect = e-108
Identities = 176/255 (69%), Positives = 206/255 (80%), Gaps = 3/255 (1%)
Frame = +2
Query: 41 RWLPFDIP--SDESVDFVTGLHTVCGAGDPRSRHGIAIHVYLCNASMDKSAFYSSDGDFL 214
RW PF+IP S + VDFV+GLHT+CGAGD +S +G+AIH++LCN SM+ FY+SDGDFL
Sbjct: 96 RWKPFEIPKASQKKVDFVSGLHTLCGAGDIKSNNGLAIHIFLCNTSMENRCFYNSDGDFL 155
Query: 215 IVPQQGKLKITTEFGLMEVAPNEIAVIQLGMRFAVFVEGPTRGYILEVFDGHFKLPDLGP 394
IVPQ+G L I TEFG M V PNEI VIQ GMRF++ V TRGYILEV+ HF+LPDLGP
Sbjct: 156 IVPQKGNLLIYTEFGKMLVQPNEICVIQRGMRFSIDVFEETRGYILEVYGVHFELPDLGP 215
Query: 395 IGANGLANPRDFLTPVAHYVDEETP-GFQIFNKYQGFLFVAEQNHNPFDVVAWHGNYVPY 571
IGANGLANPRDFL P+A Y D + P G+ + NKYQG LF A+Q+ +PF+VVAWHGNY PY
Sbjct: 216 IGANGLANPRDFLIPIAWYEDRQVPGGYTVINKYQGKLFAAKQDVSPFNVVAWHGNYTPY 275
Query: 572 KYDLNNFMVINAVLYDHCDPSIFTVLTCPSAKPGIAIADFVIFPPXWSVQEHTFRPPYYH 751
KY+L NFMVIN+V +DH DPSIFTVLT S +PG+AIADFVIFPP W V + TFRPPYYH
Sbjct: 276 KYNLKNFMVINSVAFDHADPSIFTVLTAKSVRPGVAIADFVIFPPRWGVADKTFRPPYYH 335
Query: 752 RNCMSEFMGLILGSY 796
RNCMSEFMGLI G Y
Sbjct: 336 RNCMSEFMGLIRGHY 350
>BC020792-1|AAH20792.1| 329|Homo sapiens homogentisate
1,2-dioxygenase (homogentisate oxidase) protein.
Length = 329
Score = 306 bits (751), Expect = 6e-83
Identities = 140/207 (67%), Positives = 167/207 (80%), Gaps = 3/207 (1%)
Frame = +2
Query: 41 RWLPFDIP--SDESVDFVTGLHTVCGAGDPRSRHGIAIHVYLCNASMDKSAFYSSDGDFL 214
RW PF+IP S + VDFV+GLHT+CGAGD +S +G+AIH++LCN SM+ FY+SDGDFL
Sbjct: 96 RWKPFEIPKASQKKVDFVSGLHTLCGAGDIKSNNGLAIHIFLCNTSMENRCFYNSDGDFL 155
Query: 215 IVPQQGKLKITTEFGLMEVAPNEIAVIQLGMRFAVFVEGPTRGYILEVFDGHFKLPDLGP 394
IVPQ+G L I TEFG M V PNEI VIQ GMRF++ V TRGYILEV+ HF+LPDLGP
Sbjct: 156 IVPQKGNLLIYTEFGKMLVQPNEICVIQRGMRFSIDVFEETRGYILEVYGVHFELPDLGP 215
Query: 395 IGANGLANPRDFLTPVAHYVDEETP-GFQIFNKYQGFLFVAEQNHNPFDVVAWHGNYVPY 571
IGANGLANPRDFL P+A Y D + P G+ + NKYQG LF A+Q+ +PF+VVAWHGNY PY
Sbjct: 216 IGANGLANPRDFLIPIAWYEDRQVPGGYTVINKYQGKLFAAKQDVSPFNVVAWHGNYTPY 275
Query: 572 KYDLNNFMVINAVLYDHCDPSIFTVLT 652
KY+L NFMVIN+V +DH DPSIFTVLT
Sbjct: 276 KYNLKNFMVINSVAFDHADPSIFTVLT 302
>BC012775-1|AAH12775.3| 268|Homo sapiens chromosome 19 open reading
frame 22 protein.
Length = 268
Score = 31.1 bits (67), Expect = 4.8
Identities = 14/36 (38%), Positives = 22/36 (61%)
Frame = -3
Query: 409 SISSDRSKIRQLKMTVENF*YVPPGRTLNKYSESHS 302
S S+D RQ+K++ + ++PPG L+ Y E HS
Sbjct: 233 SASADLEGKRQMKVSNRHLDFLPPGLLLSAYLEQHS 268
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 132,899,527
Number of Sequences: 237096
Number of extensions: 3118933
Number of successful extensions: 5992
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 5545
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5986
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9813323168
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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