Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P04_F_D03
(763 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q802Z1 Cluster: Zinc metallopeptidase, STE24 homolog; n... 180 5e-44
UniRef50_O75844 Cluster: CAAX prenyl protease 1 homolog; n=21; E... 175 7e-43
UniRef50_Q3Y6B8 Cluster: Membrane-associated metalloproteinase; ... 167 3e-40
UniRef50_Q7K172 Cluster: LD04933p; n=5; Diptera|Rep: LD04933p - ... 159 5e-38
UniRef50_UPI0000D55721 Cluster: PREDICTED: similar to CAAX preny... 158 1e-37
UniRef50_UPI00015B42F5 Cluster: PREDICTED: similar to farnesylat... 154 3e-36
UniRef50_Q94FS8 Cluster: CaaX processing zinc-metallo endoprotea... 146 4e-34
UniRef50_UPI0000DB7F0A Cluster: PREDICTED: similar to zinc metal... 141 1e-32
UniRef50_Q967X5 Cluster: Afc1 protein; n=1; Physarum polycephalu... 140 3e-32
UniRef50_Q4P263 Cluster: Putative uncharacterized protein; n=1; ... 129 8e-29
UniRef50_Q9XVE5 Cluster: Putative uncharacterized protein fce-1;... 124 3e-27
UniRef50_Q5KHY1 Cluster: Metalloendopeptidase, putative; n=1; Fi... 118 2e-25
UniRef50_Q54FH7 Cluster: Putative uncharacterized protein; n=1; ... 104 2e-21
UniRef50_Q10071 Cluster: Probable CAAX prenyl protease 1; n=1; S... 103 4e-21
UniRef50_Q4N3R0 Cluster: CAAX prenyl protease 1, putative; n=2; ... 103 6e-21
UniRef50_A7AV05 Cluster: CAAX metallo endopeptidase, putative; n... 101 3e-20
UniRef50_UPI0000D5722B Cluster: PREDICTED: similar to CAAX preny... 91 2e-17
UniRef50_Q2HB93 Cluster: Putative uncharacterized protein; n=1; ... 88 3e-16
UniRef50_A7HM62 Cluster: Ste24 endopeptidase; n=1; Fervidobacter... 85 2e-15
UniRef50_A2FKD2 Cluster: Clan MA, family M48, Ste24 endopeptidas... 85 2e-15
UniRef50_A6LJX8 Cluster: Ste24 endopeptidase; n=1; Thermosipho m... 83 6e-15
UniRef50_P47154 Cluster: CAAX prenyl protease 1; n=11; Eukaryota... 83 6e-15
UniRef50_Q8KCB5 Cluster: CAAX prenyl protease 1, putative; n=11;... 83 7e-15
UniRef50_Q22BD2 Cluster: Peptidase family M48 containing protein... 83 1e-14
UniRef50_Q5CLH9 Cluster: CAAX prenyl protease; n=3; Cryptosporid... 82 1e-14
UniRef50_Q11VA2 Cluster: Zn-dependent protease with chaperone fu... 80 5e-14
UniRef50_A7HAH2 Cluster: Ste24 endopeptidase; n=2; Anaeromyxobac... 78 2e-13
UniRef50_A3LZ17 Cluster: Predicted protein; n=2; Pichia stipitis... 78 3e-13
UniRef50_Q6ANN7 Cluster: Related to CAAX prenyl protease; n=1; D... 77 6e-13
UniRef50_A2E2V6 Cluster: Clan MA, family M48, Ste24 endopeptidas... 76 8e-13
UniRef50_Q1Q610 Cluster: Similar to CAAX prenyl protease 1; n=1;... 75 1e-12
UniRef50_A1AWN1 Cluster: Ste24 endopeptidase; n=2; sulfur-oxidiz... 75 2e-12
UniRef50_UPI0000498A37 Cluster: CAAX prenyl protease; n=1; Entam... 75 3e-12
UniRef50_Q4DXY8 Cluster: CAAX prenyl protease 1, putative; n=8; ... 74 3e-12
UniRef50_Q75D60 Cluster: ABR163Wp; n=1; Eremothecium gossypii|Re... 74 4e-12
UniRef50_Q54M80 Cluster: Putative uncharacterized protein; n=1; ... 73 1e-11
UniRef50_UPI0000E49E55 Cluster: PREDICTED: hypothetical protein,... 72 1e-11
UniRef50_Q4FYW8 Cluster: Metallo-peptidase, Clan M-, Family M48;... 71 2e-11
UniRef50_A7D065 Cluster: Ste24 endopeptidase; n=1; Opitutaceae b... 69 1e-10
UniRef50_Q8IHA2 Cluster: AT22982p; n=3; Sophophora|Rep: AT22982p... 69 2e-10
UniRef50_A6Q3T8 Cluster: Zinc-metallo protease; n=2; Epsilonprot... 67 4e-10
UniRef50_A1ZZ74 Cluster: Caax prenyl protease 1; n=1; Microscill... 67 4e-10
UniRef50_A4CQ25 Cluster: Caax prenyl protease 1; n=3; Flavobacte... 67 5e-10
UniRef50_Q7JV41 Cluster: AT28654p; n=2; Sophophora|Rep: AT28654p... 66 9e-10
UniRef50_A0L612 Cluster: Ste24 endopeptidase precursor; n=2; cel... 64 3e-09
UniRef50_A0LI27 Cluster: Ste24 endopeptidase precursor; n=1; Syn... 64 5e-09
UniRef50_A1WB44 Cluster: Ste24 endopeptidase precursor; n=57; Pr... 63 8e-09
UniRef50_A0E1K7 Cluster: Chromosome undetermined scaffold_73, wh... 63 8e-09
UniRef50_UPI0000E87B29 Cluster: probable transmembrane protease;... 62 1e-08
UniRef50_Q6C243 Cluster: Yarrowia lipolytica chromosome F of str... 62 1e-08
UniRef50_Q4AGI4 Cluster: Ste24 endopeptidase; n=1; Chlorobium ph... 62 1e-08
UniRef50_A7I114 Cluster: Peptidase, M48 family; n=2; Campylobact... 62 2e-08
UniRef50_Q2S4T7 Cluster: Caax prenyl protease 1; n=1; Salinibact... 60 6e-08
UniRef50_A7H4A3 Cluster: Peptidase, M48 family; n=12; Campylobac... 59 1e-07
UniRef50_Q2LYG7 Cluster: Zn-dependent protease with chaperone fu... 58 2e-07
UniRef50_Q30UQ0 Cluster: Ste24 endopeptidase precursor; n=1; Des... 58 3e-07
UniRef50_UPI00006CFC10 Cluster: Peptidase family M48 containing ... 57 4e-07
UniRef50_A6Q7V5 Cluster: Zinc metallopeptidase; n=1; Sulfurovum ... 57 5e-07
UniRef50_Q7VGH2 Cluster: Zinc-metallo protease; n=1; Helicobacte... 56 7e-07
UniRef50_Q1JZV6 Cluster: Ste24 endopeptidase; n=6; Bacteria|Rep:... 56 7e-07
UniRef50_Q60BD9 Cluster: Peptidase, M48 family; n=4; Proteobacte... 56 1e-06
UniRef50_Q18GJ2 Cluster: CAAX prenyl proteinase / zinc metallopr... 54 3e-06
UniRef50_Q7MAI4 Cluster: PUTATIVE ZINC-METALLO PROTEASE; n=1; Wo... 52 2e-05
UniRef50_A0RNE9 Cluster: Peptidase, M48 family; n=2; Campylobact... 52 2e-05
UniRef50_Q0ADS6 Cluster: Ste24 endopeptidase; n=4; Betaproteobac... 51 4e-05
UniRef50_Q74GC8 Cluster: Peptidase, M48 family; n=6; Desulfuromo... 50 8e-05
UniRef50_Q3ZYX3 Cluster: Peptidase, M48 family; n=3; Dehalococco... 41 0.029
UniRef50_Q3A4R8 Cluster: Putative FtsZ-like Zn-dependent proteas... 40 0.089
UniRef50_Q4UFQ7 Cluster: Metallo-protease, putative; n=4; Theile... 39 0.16
UniRef50_Q8SSD6 Cluster: CAAX PRENYL PROTEASE 1; n=1; Encephalit... 39 0.16
UniRef50_Q7NB70 Cluster: Putative uncharacterized protein; n=1; ... 35 1.9
UniRef50_Q1NYZ7 Cluster: Preprotein translocase SecY subunit; n=... 35 1.9
UniRef50_A2ETL9 Cluster: Putative uncharacterized protein; n=1; ... 35 2.5
UniRef50_UPI00004991B2 Cluster: hypothetical protein 173.t00010;... 34 3.3
UniRef50_Q2RJ44 Cluster: Ste24 endopeptidase precursor; n=1; Moo... 34 3.3
UniRef50_Q4CYI1 Cluster: Putative uncharacterized protein; n=5; ... 34 3.3
UniRef50_Q2U6T7 Cluster: Ferric reductase; n=6; Eurotiomycetidae... 34 3.3
UniRef50_UPI00006D0DB9 Cluster: Sodium/calcium exchanger protein... 34 4.4
UniRef50_Q8IK91 Cluster: Putative uncharacterized protein; n=1; ... 34 4.4
UniRef50_Q5ZVH0 Cluster: Serine-type D-Ala-D-Ala carboxypeptidas... 33 5.8
UniRef50_A5K0C4 Cluster: Putative uncharacterized protein; n=1; ... 33 5.8
UniRef50_A0EGC9 Cluster: Chromosome undetermined scaffold_95, wh... 33 5.8
UniRef50_Q97MN0 Cluster: Predicted ABC transporter, permease com... 33 7.7
UniRef50_Q04R76 Cluster: Cation/multidrug efflux pump; n=2; Lept... 33 7.7
>UniRef50_Q802Z1 Cluster: Zinc metallopeptidase, STE24 homolog; n=8;
Coelomata|Rep: Zinc metallopeptidase, STE24 homolog -
Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 468
Score = 180 bits (437), Expect = 5e-44
Identities = 85/221 (38%), Positives = 126/221 (57%)
Frame = +2
Query: 98 EXAILYLILLFTWVEYLWEQYLSLRQLKIYKTNNTIPEDLKEMLNEDLFKKARLYGIDKA 277
E I Y +L F+W Y+WE YL+ RQ KIY+ +P +L ++++ + F+K+RLY +DK+
Sbjct: 11 EDKIFYAVLFFSWTVYVWEAYLAYRQRKIYRATVHVPTELGKIMDSETFEKSRLYQLDKS 70
Query: 278 QFKIVKELYSTILTSVILYNKWIYVAWRKSEQIGAMFNISPDREIIISCIFMTFITLFNF 457
F LYS ++IL I W+ S + A F P+ EI S +F+ TLF+
Sbjct: 71 NFGFWSGLYSEFEGTLILLLGGIPFLWKLSGHLTAHFGFGPEYEISQSLVFLMLATLFSA 130
Query: 458 IVNKPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLGGDM 637
P+++Y FV+EE+HGFN+QT+ FF+KD +K ++ I +P+ S+ +YII +GGD
Sbjct: 131 FTGLPWSLYNTFVIEEKHGFNQQTLGFFLKDALKKFAVTQCILVPVTSLLLYIIKIGGDY 190
Query: 638 FXXXXXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLRT 760
F IAPL DKF PLPDG LR+
Sbjct: 191 FFIYAWLFTFIVSLILVTIYADYIAPLFDKFTPLPDGELRS 231
>UniRef50_O75844 Cluster: CAAX prenyl protease 1 homolog; n=21;
Eumetazoa|Rep: CAAX prenyl protease 1 homolog - Homo
sapiens (Human)
Length = 475
Score = 175 bits (427), Expect = 7e-43
Identities = 85/220 (38%), Positives = 125/220 (56%)
Frame = +2
Query: 98 EXAILYLILLFTWVEYLWEQYLSLRQLKIYKTNNTIPEDLKEMLNEDLFKKARLYGIDKA 277
E I +LLF+W YLWE +L+ RQ +IYKT +P +L ++++ + F+K+RLY +DK+
Sbjct: 16 EKRIFGAVLLFSWTVYLWETFLAQRQRRIYKTTTHVPPELGQIMDSETFEKSRLYQLDKS 75
Query: 278 QFKIVKELYSTILTSVILYNKWIYVAWRKSEQIGAMFNISPDREIIISCIFMTFITLFNF 457
F LYS ++IL I WR S + P+ EI S +F+ TLF+
Sbjct: 76 TFSFWSGLYSETEGTLILLFGGIPYLWRLSGRFCGYAGFGPEYEITQSLVFLLLATLFSA 135
Query: 458 IVNKPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLGGDM 637
+ P+++Y FV+EE+HGFN+QT+ FF+KD IK ++ I LP+ S+ +YII +GGD
Sbjct: 136 LTGLPWSLYNTFVIEEKHGFNQQTLGFFMKDAIKKFVVTQCILLPVSSLLLYIIKIGGDY 195
Query: 638 FXXXXXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLR 757
F IAPL DKF PLP+G L+
Sbjct: 196 FFIYAWLFTLVVSLVLVTIYADYIAPLFDKFTPLPEGKLK 235
>UniRef50_Q3Y6B8 Cluster: Membrane-associated metalloproteinase;
n=2; Platyhelminthes|Rep: Membrane-associated
metalloproteinase - Taenia solium (Pork tapeworm)
Length = 472
Score = 167 bits (406), Expect = 3e-40
Identities = 88/221 (39%), Positives = 125/221 (56%), Gaps = 8/221 (3%)
Frame = +2
Query: 119 ILLFTWVEYLWEQYLSLRQLKIYKTNNTIPEDLKEMLNEDLFKKARLYGIDKAQFKIVKE 298
IL+F WV +LWE Y++LRQLK+ K PE++K ++N+ F K+R Y IDK F IV
Sbjct: 20 ILIFIWVLFLWETYINLRQLKVAKRVTESPEEIKCLMNDVDFDKSRRYAIDKMNFDIVSG 79
Query: 299 LYSTILTSVILYNKWIYVAWRKSEQ--------IGAMFNISPDREIIISCIFMTFITLFN 454
Y+ + S +LY + I AW KS++ F + EI+ S +F ++ LF
Sbjct: 80 FYNILSLSAVLYFQLIAWAWHKSQEHMLFVCSYAPRSFGTTEGSEILFSLLFTVYVALFQ 139
Query: 455 FIVNKPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLGGD 634
F + P++ Y FV+EER+GFNKQT+ FFIKD++KSL + LVI LPIIS+ ++II GG
Sbjct: 140 FFESLPWSYYRHFVIEERYGFNKQTIGFFIKDRLKSLAVGLVIGLPIISMLVWIIKAGGH 199
Query: 635 MFXXXXXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLR 757
F IAP+ D++ PD LR
Sbjct: 200 YFYIYAYGFTFVVSFIIMFIYPEFIAPIFDRYEHFPDCELR 240
>UniRef50_Q7K172 Cluster: LD04933p; n=5; Diptera|Rep: LD04933p -
Drosophila melanogaster (Fruit fly)
Length = 451
Score = 159 bits (387), Expect = 5e-38
Identities = 85/224 (37%), Positives = 119/224 (53%), Gaps = 1/224 (0%)
Frame = +2
Query: 89 NFDEXAILYLILLFTWVEYLWEQYLSLRQLKIYKTNNTIPEDLKEMLNEDLFKKARLYGI 268
+ D +L IL +E E Y+SLRQ+K+Y+T +P +LK + ED F KAR YG+
Sbjct: 3 SLDADTVLLSILFLVVIENALEIYISLRQVKVYQTALKVPAELKSHMGEDTFHKARKYGL 62
Query: 269 DKAQFKIVKELYSTI-LTSVILYNKWIYVAWRKSEQIGAMFNISPDREIIISCIFMTFIT 445
D+ +F I K + + L + LY I V W+ S Q+ EII+SC+F+
Sbjct: 63 DQEKFGIFKAVVMDVALLCMELYIGLIAVLWQLSVQVVDKLQWDSKNEIIVSCVFVLISN 122
Query: 446 LFNFIVNKPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIML 625
+ + PF IY +FVLEE HGFNKQT RFF DQ+K ++ V+ +PI + I+I+
Sbjct: 123 VLSTFKGLPFKIYKIFVLEETHGFNKQTARFFAWDQLKGFLVTQVLMIPITAAIIFIVQR 182
Query: 626 GGDMFXXXXXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLR 757
GGD F IAPL DK+ PL G+LR
Sbjct: 183 GGDNFFIWLWIFTGVISLVLLTLYPIFIAPLFDKYTPLEKGALR 226
>UniRef50_UPI0000D55721 Cluster: PREDICTED: similar to CAAX prenyl
protease 1 homolog (Prenyl protein-specific endoprotease
1) (Farnesylated proteins-converting enzyme 1) (FACE-1)
(Zinc metalloproteinase Ste24 homolog); n=1; Tribolium
castaneum|Rep: PREDICTED: similar to CAAX prenyl
protease 1 homolog (Prenyl protein-specific endoprotease
1) (Farnesylated proteins-converting enzyme 1) (FACE-1)
(Zinc metalloproteinase Ste24 homolog) - Tribolium
castaneum
Length = 430
Score = 158 bits (384), Expect = 1e-37
Identities = 86/226 (38%), Positives = 123/226 (54%)
Frame = +2
Query: 83 IMNFDEXAILYLILLFTWVEYLWEQYLSLRQLKIYKTNNTIPEDLKEMLNEDLFKKARLY 262
++ +E + Y IL F W EYLWE YLS+RQ K +P +L+ + ++ F KARLY
Sbjct: 1 MITLNEVFVKYAILFFLWSEYLWELYLSIRQHKKGHATTEVPPELRNTMTKETFSKARLY 60
Query: 263 GIDKAQFKIVKELYSTILTSVILYNKWIYVAWRKSEQIGAMFNISPDREIIISCIFMTFI 442
+ K++F +VK+ +S I ++VI+Y + W ++ + E++ SC+++ +
Sbjct: 61 MLAKSKFGMVKDTFSVIESTVIIYFGILPKIWDYAQSLNPY-----GGEVLTSCLWLFIL 115
Query: 443 TLFNFIVNKPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIM 622
T IV+ P TIY FVLEE GFNKQT FFI D+IK+ LS V T+ I SV + I
Sbjct: 116 TTILTIVDLPLTIYNTFVLEENFGFNKQTSGFFIWDKIKAYILSQVFTMMISSVIVVTIQ 175
Query: 623 LGGDMFXXXXXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLRT 760
GG F IAPL DK+ PLP+G LRT
Sbjct: 176 SGGAYFFVWLWIVVCLICFIMYAIYPSFIAPLFDKYTPLPEGELRT 221
>UniRef50_UPI00015B42F5 Cluster: PREDICTED: similar to
farnesylated-proteins converting enzyme-1; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to
farnesylated-proteins converting enzyme-1 - Nasonia
vitripennis
Length = 486
Score = 154 bits (373), Expect = 3e-36
Identities = 73/218 (33%), Positives = 125/218 (57%), Gaps = 1/218 (0%)
Frame = +2
Query: 107 ILYLILLFTWVEYLWEQYLSLRQLKIYKTNNTIPEDLKEMLNEDLFKKARLYGIDKAQFK 286
IL +++ +W+ +LWE YL+ RQ ++ + P+ L ++ ED++KKAR Y +DK+ F+
Sbjct: 29 ILTELVVISWIIFLWELYLTFRQRRLVQKLAEPPKVLDGLVEEDVYKKARSYSLDKSTFE 88
Query: 287 IVKELYSTILTSVILYNKWIYVAWRKSEQIGAMFNISPDREIIISCIFMTFITLFNFIV- 463
IV+++YS ++ ++ + Y W + + + P EI ++ +T + +++ I+
Sbjct: 89 IVQDVYSNVINTIFMTCWGFYFVWIWGKYLVEYVGLDPKNEIYVTAGCITVMRIYSTILC 148
Query: 464 NKPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLGGDMFX 643
+ PFT+Y FVLE++H FN QT FFIKDQI +S ++ +P+I ++I+M GGD F
Sbjct: 149 DLPFTVYDTFVLEQKHNFNNQTPLFFIKDQIIKFLVSQILMVPLICGMVWIVMNGGDYFF 208
Query: 644 XXXXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLR 757
IAPL DK+ PLP+G L+
Sbjct: 209 LYLWLFTVGMSLLLMIIYPELIAPLFDKYTPLPEGDLK 246
>UniRef50_Q94FS8 Cluster: CaaX processing zinc-metallo endoprotease;
n=11; Magnoliophyta|Rep: CaaX processing zinc-metallo
endoprotease - Arabidopsis thaliana (Mouse-ear cress)
Length = 424
Score = 146 bits (355), Expect = 4e-34
Identities = 74/210 (35%), Positives = 116/210 (55%)
Frame = +2
Query: 128 FTWVEYLWEQYLSLRQLKIYKTNNTIPEDLKEMLNEDLFKKARLYGIDKAQFKIVKELYS 307
F V Y++E YL LRQL K T+P+ L +++++ F+K+R Y +DK+ F V E +
Sbjct: 12 FMIVMYIFETYLDLRQLTALKLP-TLPKTLVGVISQEKFEKSRAYSLDKSYFHFVHEFVT 70
Query: 308 TILTSVILYNKWIYVAWRKSEQIGAMFNISPDREIIISCIFMTFITLFNFIVNKPFTIYG 487
++ S IL+ + W+ S + + P+ EI+ + F+ + ++ I + PF++Y
Sbjct: 71 ILMDSAILFFGILPWFWKMSGAVLPRLGLDPENEILHTLSFLAGVMTWSQITDLPFSLYS 130
Query: 488 VFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLGGDMFXXXXXXXXX 667
FV+E RHGFNKQT+ FI+D IK FLS+++ PI++ I+I+ GG
Sbjct: 131 TFVIESRHGFNKQTIWMFIRDMIKGTFLSVILGPPIVAAIIFIVQKGGPYLAIYLWAFMF 190
Query: 668 XXXXXXXXXXXXXIAPLXDKFVPLPDGSLR 757
IAPL +KF PLPDG LR
Sbjct: 191 ILSLVMMTIYPVLIAPLFNKFTPLPDGDLR 220
>UniRef50_UPI0000DB7F0A Cluster: PREDICTED: similar to zinc
metalloproteinase, STE24 homolog; n=1; Apis
mellifera|Rep: PREDICTED: similar to zinc
metalloproteinase, STE24 homolog - Apis mellifera
Length = 433
Score = 141 bits (342), Expect = 1e-32
Identities = 71/225 (31%), Positives = 117/225 (52%)
Frame = +2
Query: 86 MNFDEXAILYLILLFTWVEYLWEQYLSLRQLKIYKTNNTIPEDLKEMLNEDLFKKARLYG 265
+ F E ILY IL +W+ +LW+ YL LRQ +P+ L+ ++ +D++ KA Y
Sbjct: 5 VRFIEENILYEILAISWLLFLWKFYLDLRQRVFMMRLTNLPKSLEGLMTKDVYNKAHNYL 64
Query: 266 IDKAQFKIVKELYSTILTSVILYNKWIYVAWRKSEQIGAMFNISPDREIIISCIFMTFIT 445
+D+ +F + +YS + T + L + W S + F + + EI++S I M ++
Sbjct: 65 LDRLKFDSFESIYSELCTMIFLLTLCYHRFWLWSINLVKYFGFNDENEILLSGICMFILS 124
Query: 446 LFNFIVNKPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIML 625
N I+ PF +Y FV+E+ +GFNK+T FF KDQ+ + +I +P++ I+II
Sbjct: 125 TINDIIFLPFKVYFTFVVEQAYGFNKETPLFFAKDQLLKFIVHQIIVVPLLCAVIWIIKS 184
Query: 626 GGDMFXXXXXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLRT 760
GG+ IAP+ DK+ PLP+G L+T
Sbjct: 185 GGEYCFLYLWIFLIVAALFLMIIYPEVIAPIFDKYTPLPNGDLKT 229
>UniRef50_Q967X5 Cluster: Afc1 protein; n=1; Physarum
polycephalum|Rep: Afc1 protein - Physarum polycephalum
(Slime mold)
Length = 419
Score = 140 bits (340), Expect = 3e-32
Identities = 75/216 (34%), Positives = 115/216 (53%), Gaps = 2/216 (0%)
Frame = +2
Query: 116 LILLFTWVEYLWEQYLSLRQLKIYKTNNTIPEDLKE--MLNEDLFKKARLYGIDKAQFKI 289
LIL F YL E YL +RQ YK +PE +K+ ++ ++ F K++ YG+DK+ F
Sbjct: 2 LILGFVTFSYLLETYLDIRQHNNYKVK-VLPEKIKKYNIITQEEFAKSQAYGLDKSNFGF 60
Query: 290 VKELYSTILTSVILYNKWIYVAWRKSEQIGAMFNISPDREIIISCIFMTFITLFNFIVNK 469
+ + + ++L + W S F D E++ SC+F+ + L + I++
Sbjct: 61 FHDFFDFVQNILVLVCGVLPYLWGVSAVPLRKFGYE-DSEVLHSCVFVVLLILLSSIISM 119
Query: 470 PFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLGGDMFXXX 649
PF +Y FV+EERHGFNKQT+ + KD++KS L +VI LPI+S + +I +GG F
Sbjct: 120 PFELYSTFVIEERHGFNKQTLGLYFKDKVKSFLLFIVIGLPILSAVLLLIKMGGPHFWFY 179
Query: 650 XXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLR 757
IAP+ +KF PLP+G LR
Sbjct: 180 LWLFLIAVTLIMVTIYPTLIAPIFNKFEPLPEGDLR 215
>UniRef50_Q4P263 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 497
Score = 129 bits (311), Expect = 8e-29
Identities = 80/224 (35%), Positives = 114/224 (50%), Gaps = 3/224 (1%)
Frame = +2
Query: 95 DEXAILY--LILLFTWVEYLWEQYLSLRQLKIYKTNNTIPEDLKEMLNEDLFKKARLYGI 268
D+ AI + L+L W+ Y +E LSLRQ ++Y T P L ++ D FKK+++YG
Sbjct: 17 DDPAIQWKKLVLALLWLVYAFETLLSLRQYRLYSLE-TPPATLASHVDLDTFKKSQVYGR 75
Query: 269 DKAQFKIVKELYSTILTSVILYNKWIYV-AWRKSEQIGAMFNISPDREIIISCIFMTFIT 445
DKA+F S ++ SV L + IY +W + I F S D EI S ++M +
Sbjct: 76 DKARFGFFSSAVSQLI-SVALVHYDIYAWSWTLAGTILTHFGQS-DSEIPRSIVWMVIMF 133
Query: 446 LFNFIVNKPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIML 625
+ + P T+Y FV+EERHGFNK T+R F+ D +K L VI +P+IS ++II
Sbjct: 134 VIREVPGMPLTLYRNFVIEERHGFNKMTIRTFVTDTLKEWMLGFVIGVPLISALLWIIRW 193
Query: 626 GGDMFXXXXXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLR 757
G F I PL +K PLP G+LR
Sbjct: 194 AGSAFVSYVVVFLFSFQMIAMVLYPTVIQPLFNKLTPLPQGALR 237
>UniRef50_Q9XVE5 Cluster: Putative uncharacterized protein fce-1;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein fce-1 - Caenorhabditis elegans
Length = 442
Score = 124 bits (298), Expect = 3e-27
Identities = 65/222 (29%), Positives = 110/222 (49%)
Frame = +2
Query: 95 DEXAILYLILLFTWVEYLWEQYLSLRQLKIYKTNNTIPEDLKEMLNEDLFKKARLYGIDK 274
D + +L W +LW+QY++ RQ K +K P ++KE++ E+ +KKAR Y ID
Sbjct: 2 DASCLFKALLATNWALFLWDQYITFRQYKAHKNAVKRPNEVKELIGEEDYKKARDYKIDN 61
Query: 275 AQFKIVKELYSTILTSVILYNKWIYVAWRKSEQIGAMFNISPDREIIISCIFMTFITLFN 454
F ++ +L + L + W + A + + +F++ ++
Sbjct: 62 HLFGFFHSWFNQLLLTAQLIGGYYPFLWYAT----ASYPLH-------VAVFLSINSIIE 110
Query: 455 FIVNKPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLGGD 634
I++ P+ +Y F++E+ HGFNKQT+ F+ D+IK + + +T+PI+ +II+ GG
Sbjct: 111 TIIDLPWDLYSTFIIEDAHGFNKQTIGFYFVDKIKKMLVGFALTMPIVYGIEWIIVNGGP 170
Query: 635 MFXXXXXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLRT 760
F IAPL DK+ PLPDG L+T
Sbjct: 171 YFFVYIWLFVSVVVLLLMTIYPTFIAPLFDKYFPLPDGDLKT 212
>UniRef50_Q5KHY1 Cluster: Metalloendopeptidase, putative; n=1;
Filobasidiella neoformans|Rep: Metalloendopeptidase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 460
Score = 118 bits (284), Expect = 2e-25
Identities = 66/216 (30%), Positives = 111/216 (51%)
Frame = +2
Query: 113 YLILLFTWVEYLWEQYLSLRQLKIYKTNNTIPEDLKEMLNEDLFKKARLYGIDKAQFKIV 292
++++L TW++ +E Y+ RQL Y P LK L D F+KA+ Y DK +F+++
Sbjct: 29 FIVVLSTWLQTAFEVYILRRQLPCYD-RPAPPPALKAHLEGDTFRKAQTYSRDKTRFQLL 87
Query: 293 KELYSTILTSVILYNKWIYVAWRKSEQIGAMFNISPDREIIISCIFMTFITLFNFIVNKP 472
+ +++ IL +++ + W + + + + P+ I+ S +++T +TL I P
Sbjct: 88 QLVFNQILGWIMIKSGAYSKLWDVAGRFTNLLGLGPNWIIVRSLVWITILTLSTAIPGLP 147
Query: 473 FTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLGGDMFXXXX 652
++ Y FVLEE+HGFNK T ++ D +KS L ++ LP+++ + II L G F
Sbjct: 148 WSYYQTFVLEEKHGFNKSTRTLWVMDTLKSYLLFALLGLPVLAGFLKIIELSGKSFVPWL 207
Query: 653 XXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLRT 760
I PL +K PLP G LRT
Sbjct: 208 MLFLVCVQLTLQIIYPTFIQPLFNKLAPLPAGELRT 243
>UniRef50_Q54FH7 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 426
Score = 104 bits (250), Expect = 2e-21
Identities = 65/209 (31%), Positives = 96/209 (45%)
Frame = +2
Query: 128 FTWVEYLWEQYLSLRQLKIYKTNNTIPEDLKEMLNEDLFKKARLYGIDKAQFKIVKELYS 307
F +E+ + YL+ RQ K+ K +PE K+ + ++ FKK++ Y K +K +
Sbjct: 11 FFLLEHFYSFYLNFRQSKLLKNLTKVPEYCKDRITQEDFKKSQEYSKAKLDYKTLTSTIQ 70
Query: 308 TILTSVILYNKWIYVAWRKSEQIGAMFNISPDREIIISCIFMTFITLFNFIVNKPFTIYG 487
+ T + Y W S ++ I EII SC F F + I PF+ Y
Sbjct: 71 VLTTLLSFYYPVYPYFWNLSLELAE--KIGYPNEIIRSCFFFAFTVGVSVITEIPFSYYY 128
Query: 488 VFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLGGDMFXXXXXXXXX 667
F+LEE+ G+N+ T FIKD+I S L + LPI+S+AI+II G
Sbjct: 129 QFILEEKFGYNRMTRTLFIKDKIISTLLMIGFGLPILSLAIFIINWSGPQLWFYCWLLLV 188
Query: 668 XXXXXXXXXXXXXIAPLXDKFVPLPDGSL 754
I PL +KF P+ DG L
Sbjct: 189 AITLLSITIYPTFIQPLFNKFTPV-DGEL 216
>UniRef50_Q10071 Cluster: Probable CAAX prenyl protease 1; n=1;
Schizosaccharomyces pombe|Rep: Probable CAAX prenyl
protease 1 - Schizosaccharomyces pombe (Fission yeast)
Length = 474
Score = 103 bits (248), Expect = 4e-21
Identities = 64/217 (29%), Positives = 105/217 (48%), Gaps = 6/217 (2%)
Frame = +2
Query: 128 FTWVEYLWEQYLSLRQLKIYKTNNTIPEDLKEMLNEDLFKKARLYGIDKAQFKIVKELYS 307
F+ +Y W+ YL RQ+ Y P L E ++E ++KA Y DK+ F + ++
Sbjct: 55 FSIGKYAWDLYLRRRQVP-YLLREKPPAILAEHVDEKKYQKALSYARDKSWFSTIVSTFT 113
Query: 308 TILTSVILYNKWIYVAWRKS-----EQIGAMFN-ISPDREIIISCIFMTFITLFNFIVNK 469
+ +I+ + W + +++ A + S I SC+FM +TLF+ ++
Sbjct: 114 LAVDLLIIKYDGLSYLWNITKFPWMDKLAASSSRFSLSTSITHSCVFMFGLTLFSRLIQI 173
Query: 470 PFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLGGDMFXXX 649
PF +Y FV+EE++GFNK T++ F+ D +K L L ++ ++ V + I+ GD F
Sbjct: 174 PFNLYSTFVIEEKYGFNKSTLKIFVIDLLKELSLGGLLMSVVVGVFVKILTKFGDNFIMY 233
Query: 650 XXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLRT 760
I PL KF PL +GSLRT
Sbjct: 234 AWGAYIVFGLILQTIAPSLIMPLFYKFTPLENGSLRT 270
>UniRef50_Q4N3R0 Cluster: CAAX prenyl protease 1, putative; n=2;
Theileria|Rep: CAAX prenyl protease 1, putative -
Theileria parva
Length = 444
Score = 103 bits (246), Expect = 6e-21
Identities = 62/193 (32%), Positives = 96/193 (49%)
Frame = +2
Query: 179 KIYKTNNTIPEDLKEMLNEDLFKKARLYGIDKAQFKIVKELYSTILTSVILYNKWIYVAW 358
+IYK T+ E + E LN D +KK Y DK +F + L+ + +L+ + W
Sbjct: 56 RIYK--KTL-ESVSEYLNSDDYKKTVEYSYDKLKFNVFNSLFHFLFDLFLLFVLFSPKLW 112
Query: 359 RKSEQIGAMFNISPDREIIISCIFMTFITLFNFIVNKPFTIYGVFVLEERHGFNKQTVRF 538
+ S ++ + + E S +F LF+ +V PF +Y FVLEE+HGFNK+T +
Sbjct: 113 KFSGKV-----LKKNNEYTQSLVFCGIKMLFDTMVELPFGLYSDFVLEEKHGFNKKTYKL 167
Query: 539 FIKDQIKSLFLSLVITLPIISVAIYIIMLGGDMFXXXXXXXXXXXXXXXXXXXXXXIAPL 718
F+KD + +L L VI P++ I+++ GG++F IAPL
Sbjct: 168 FVKDLLLTLLLQCVIGGPVLCALIFLVNWGGELFYFYVFGFIVVFNFIMLIVYPELIAPL 227
Query: 719 XDKFVPLPDGSLR 757
+KF PL D LR
Sbjct: 228 FNKFEPLHDEELR 240
>UniRef50_A7AV05 Cluster: CAAX metallo endopeptidase, putative; n=1;
Babesia bovis|Rep: CAAX metallo endopeptidase, putative
- Babesia bovis
Length = 448
Score = 101 bits (241), Expect = 3e-20
Identities = 60/178 (33%), Positives = 91/178 (51%)
Frame = +2
Query: 224 MLNEDLFKKARLYGIDKAQFKIVKELYSTILTSVILYNKWIYVAWRKSEQIGAMFNISPD 403
+L++D K Y DK F+IV ++ TIL V+L+ Y R + G++ +
Sbjct: 73 LLSDDYHKTVE-YARDKLIFQIVTSIFQTILAMVLLF---YYFGPRLWKYAGSL--LKHP 126
Query: 404 REIIISCIFMTFITLFNFIVNKPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVI 583
E S IF + + I+ PF++Y FVLEE+HGFNK+T+R F KD + S L +VI
Sbjct: 127 SETYQSLIFCGIKAVIDTIIEIPFSLYSDFVLEEKHGFNKKTIRLFFKDLLISFGLQIVI 186
Query: 584 TLPIISVAIYIIMLGGDMFXXXXXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLR 757
P++S+ I+++ GG+ F IAPL +KF PL D L+
Sbjct: 187 GAPVLSIVIFLVNWGGEYFYLYVGVFVAVFYLFMMVIYPDFIAPLFNKFEPLNDNELK 244
>UniRef50_UPI0000D5722B Cluster: PREDICTED: similar to CAAX prenyl
protease 1 homolog (Prenyl protein-specific endoprotease
1) (Farnesylated proteins-converting enzyme 1) (FACE-1)
(Zinc metalloproteinase Ste24 homolog); n=1; Tribolium
castaneum|Rep: PREDICTED: similar to CAAX prenyl
protease 1 homolog (Prenyl protein-specific endoprotease
1) (Farnesylated proteins-converting enzyme 1) (FACE-1)
(Zinc metalloproteinase Ste24 homolog) - Tribolium
castaneum
Length = 419
Score = 91.5 bits (217), Expect = 2e-17
Identities = 52/175 (29%), Positives = 92/175 (52%)
Frame = +2
Query: 116 LILLFTWVEYLWEQYLSLRQLKIYKTNNTIPEDLKEMLNEDLFKKARLYGIDKAQFKIVK 295
++++F W++YLW QYL RQ K K +P++L L++ F K+R + + + VK
Sbjct: 9 VLIVFLWIDYLWVQYLRARQHKKTKVTTRVPDEL--ALSQQSFDKSRKQTLQRNRLAFVK 66
Query: 296 ELYSTILTSVILYNKWIYVAWRKSEQIGAMFNISPDREIIISCIFMTFITLFNFIVNKPF 475
+L S I T+ I+ K + W +++ +G + EI SC++ F T F +N PF
Sbjct: 67 DLVSIITTTAIIQYKILPTIWEETDPLGEL------DEITRSCMWYFFYTTFLAFINLPF 120
Query: 476 TIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLGGDMF 640
TIY +LE ++ F I +Q+K+ + + + + S+ I +I G +F
Sbjct: 121 TIYDSIILE-----TSKSPEFVIWNQLKNFVVGQIFAVMLCSLLITLIRNGDQVF 170
>UniRef50_Q2HB93 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 341
Score = 87.8 bits (208), Expect = 3e-16
Identities = 56/173 (32%), Positives = 90/173 (52%), Gaps = 1/173 (0%)
Frame = +2
Query: 116 LILLFTWVEYLWEQYLSLRQLKIYKTNNTIPEDLKEMLNEDLFKKARLYGIDKAQFKIVK 295
LI+ F+ +Y++E L RQ KI + P+ L+ +++++F K++ YG KA+F
Sbjct: 21 LIIGFSVGQYVFEALLGYRQYKILQKTKP-PKVLEHEVSQEVFDKSQAYGRAKAKFTGFN 79
Query: 296 ELYSTILTSVILYNKWIYVAWRKSEQIGAMFNISP-DREIIISCIFMTFITLFNFIVNKP 472
LY + + + W + + F EI S +F+ L N +++ P
Sbjct: 80 GLYGQLQNLAFYHFDVLPKLWSWTGDLLLRFAPKGFTGEISHSIVFILSFILINQVLSLP 139
Query: 473 FTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLGG 631
IY FVLEE+ GFNKQT + F+ D IK+ L+ V+T PI+S + II G
Sbjct: 140 SNIYNTFVLEEKFGFNKQTPKLFVVDMIKTNLLAFVLTPPILSGFLAIIQKTG 192
>UniRef50_A7HM62 Cluster: Ste24 endopeptidase; n=1; Fervidobacterium
nodosum Rt17-B1|Rep: Ste24 endopeptidase -
Fervidobacterium nodosum Rt17-B1
Length = 406
Score = 85.0 bits (201), Expect = 2e-15
Identities = 60/217 (27%), Positives = 108/217 (49%)
Frame = +2
Query: 107 ILYLILLFTWVEYLWEQYLSLRQLKIYKTNNTIPEDLKEMLNEDLFKKARLYGIDKAQFK 286
I LILL + E +WE LSL LK +P+ L ++++ + F+KA+ Y D+ F
Sbjct: 3 IKVLILLVIFKE-IWEVVLSLANLKYSLNTKNVPDILSDIMSAENFEKAKRYLKDRTMFS 61
Query: 287 IVKELYSTILTSVILYNKWIYVAWRKSEQIGAMFNISPDREIIISCIFMTFITLFNFIVN 466
V L + I+T V L + ++ E+I + N++ + + + +F L +F+++
Sbjct: 62 AVSTLVNLIVTLVFLLKGYPFL-----EKI--VSNLTAN-VYLQALLFAGIYGLIDFLID 113
Query: 467 KPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLGGDMFXX 646
PF ++ FV+E+++GFN T++ FI D + S+ L + I PI+ +++ + ++
Sbjct: 114 LPFKLFSTFVIEQKYGFNTTTLKTFIFDSLLSIVLIVTIATPILIGSMW-FLTHFTIWWW 172
Query: 647 XXXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLR 757
IAPL KF L DG L+
Sbjct: 173 QLSILVFLFLLFFSYIQPILIAPLFYKFTELKDGELK 209
>UniRef50_A2FKD2 Cluster: Clan MA, family M48, Ste24
endopeptidase-like metallopeptidase; n=1; Trichomonas
vaginalis G3|Rep: Clan MA, family M48, Ste24
endopeptidase-like metallopeptidase - Trichomonas
vaginalis G3
Length = 407
Score = 84.6 bits (200), Expect = 2e-15
Identities = 51/169 (30%), Positives = 86/169 (50%)
Frame = +2
Query: 125 LFTWVEYLWEQYLSLRQLKIYKTNNTIPEDLKEMLNEDLFKKARLYGIDKAQFKIVKELY 304
L + + YL+LRQ K P+ K+ + ++ F+K + Y DK F +++ +
Sbjct: 8 LLVVLSFFLSTYLTLRQRKTILRATEPPKIFKDKITDEKFQKEKAYQTDKINFALLQSVI 67
Query: 305 STILTSVILYNKWIYVAWRKSEQIGAMFNISPDREIIISCIFMTFITLFNFIVNKPFTIY 484
S L V+ K+I W FN EII S IF+ + I++ PF+ Y
Sbjct: 68 SFFL--VLFKVKFIGTFWN-------FFNYGG--EIIHSLIFLDVFDVIGTIIDLPFSYY 116
Query: 485 GVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLGG 631
FV+EE++GFNK T + ++ D +KS +SL++T ++ + I+I G
Sbjct: 117 STFVIEEKYGFNKSTKKLWVTDILKSQAISLILTDILVPIIIFIFRKAG 165
>UniRef50_A6LJX8 Cluster: Ste24 endopeptidase; n=1; Thermosipho
melanesiensis BI429|Rep: Ste24 endopeptidase -
Thermosipho melanesiensis BI429
Length = 406
Score = 83.4 bits (197), Expect = 6e-15
Identities = 51/215 (23%), Positives = 101/215 (46%)
Frame = +2
Query: 113 YLILLFTWVEYLWEQYLSLRQLKIYKTNNTIPEDLKEMLNEDLFKKARLYGIDKAQFKIV 292
Y+ L+ + +W+ LS+ + T+PE L++ +E+ K + +Y D ++
Sbjct: 4 YIFLIVFLLNTIWDTVLSIWNVNYSSRKTTVPEVLRDRFSEEYLKNSSMYLKDVTMVNVI 63
Query: 293 KELYSTILTSVILYNKWIYVAWRKSEQIGAMFNISPDREIIISCIFMTFITLFNFIVNKP 472
L +T+++ + ++ W + + + I+ D I+ F I + I++ P
Sbjct: 64 LNLINTLISLIFIF--WGFTYFENF-----VLKIT-DSLILQGLFFFGIIWIIYKILSLP 115
Query: 473 FTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLGGDMFXXXX 652
IY FV+E R+GFN T + F+ D +KSL ++ ++ +P+IS ++I+ + +
Sbjct: 116 TEIYRNFVIEARYGFNTMTPKIFVSDFLKSLLVTAILFIPLISFLLWILETDNNWW-WKI 174
Query: 653 XXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLR 757
+APL +KF PL D L+
Sbjct: 175 SIFFVGFQLLMLLIYPLYLAPLFNKFTPLKDEKLK 209
>UniRef50_P47154 Cluster: CAAX prenyl protease 1; n=11;
Eukaryota|Rep: CAAX prenyl protease 1 - Saccharomyces
cerevisiae (Baker's yeast)
Length = 453
Score = 83.4 bits (197), Expect = 6e-15
Identities = 60/216 (27%), Positives = 104/216 (48%), Gaps = 6/216 (2%)
Frame = +2
Query: 128 FTWVEYLWEQYLSLRQLKIYKTNNT-IPEDLKEMLNEDLFKKARLYGIDKAQFKIVKELY 304
F+ ++ +E YL+ RQ + K + T +P L++ ++++ F K+R Y KA+F I ++Y
Sbjct: 22 FSIAQFSFESYLTYRQYQ--KLSETKLPPVLEDEIDDETFHKSRNYSRAKAKFSIFGDVY 79
Query: 305 STILTSVILYNKWIYVAWRKSEQIGAMFNISPDREIIISCI-----FMTFITLFNFIVNK 469
+ V + W + + + + P R ++S + F+ ++ + +V+
Sbjct: 80 NLAQKLVFIKYDLFPKIWHMA--VSLLNAVLPVRFHMVSTVAQSLCFLGLLSSLSTLVDL 137
Query: 470 PFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLGGDMFXXX 649
P + Y FVLEE+ GFNK TV+ +I D IKSL L+ I PI+ + + I F
Sbjct: 138 PLSYYSHFVLEEKFGFNKLTVQLWITDMIKSLTLAYAIGGPILYLFLKIFDKFPTDFLWY 197
Query: 650 XXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLR 757
I P+ +KF PL DG L+
Sbjct: 198 IMVFLFVVQILAMTIIPVFIMPMFNKFTPLEDGELK 233
>UniRef50_Q8KCB5 Cluster: CAAX prenyl protease 1, putative; n=11;
Bacteria|Rep: CAAX prenyl protease 1, putative -
Chlorobium tepidum
Length = 415
Score = 83.0 bits (196), Expect = 7e-15
Identities = 52/213 (24%), Positives = 98/213 (46%)
Frame = +2
Query: 119 ILLFTWVEYLWEQYLSLRQLKIYKTNNTIPEDLKEMLNEDLFKKARLYGIDKAQFKIVKE 298
I+LFT + W L+ L + + T+PE +++ + +++++ Y +F ++
Sbjct: 9 IILFTLIG-TWLIKLAADLLNLRAASPTLPEAFRDVYDPADYRRSQEYLRANTKFSLISS 67
Query: 299 LYSTILTSVILYNKWIYVAWRKSEQIGAMFNISPDREIIISCIFMTFITLFNFIVNKPFT 478
+ L V W + +Q+ + P +I +++ + L + + PF+
Sbjct: 68 TFDLALLLVF----WFAGGFNALDQLIRAWGFDP---VINGVLYIGALLLLQSVADLPFS 120
Query: 479 IYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLGGDMFXXXXXX 658
IY FVLEER GFN+ T + F+ D IK+L L+++I P+++ ++ G +
Sbjct: 121 IYHTFVLEERFGFNQTTPKVFVIDLIKTLLLAVLIGTPVLAAILWFFQSAGPLGWLWAWG 180
Query: 659 XXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLR 757
I P+ +KF PL DG LR
Sbjct: 181 GVTAFSLLLQYVAPTWIMPMFNKFEPLEDGELR 213
>UniRef50_Q22BD2 Cluster: Peptidase family M48 containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Peptidase family
M48 containing protein - Tetrahymena thermophila SB210
Length = 476
Score = 82.6 bits (195), Expect = 1e-14
Identities = 58/226 (25%), Positives = 104/226 (46%), Gaps = 1/226 (0%)
Frame = +2
Query: 83 IMNFDEXAILYLILLFTWVEYLWEQYLSLRQLKIYKTNNTIPEDLKEM-LNEDLFKKARL 259
I ++ ++Y+ + V +L +Q L+ QL Y P+++K++ E F +++
Sbjct: 51 IEQVEKYPLVYIAIGIQIVFHLIDQILNYLQLT-YSQRRDRPKEIKQLGFTEREFVLSQV 109
Query: 260 YGIDKAQFKIVKELYSTILTSVILYNKWIYVAWRKSEQIGAMFNISPDREIIISCIFMTF 439
Y DK F + +S + V L W +I I + E + F+
Sbjct: 110 YSFDKLVFGSISSAFSQGIKIVFLLGYLNPFIWNNVSKILPF--IDKESEFQNAYGFLLL 167
Query: 440 ITLFNFIVNKPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYII 619
+L + ++ PF+ + F LE+R+GFN+ T++ FI D IK+ +S VIT+ ++ + ++
Sbjct: 168 QSLLDQVLEIPFSYFQTFTLEQRYGFNQTTLKIFITDIIKNNIISQVITVVLLFGYLKVV 227
Query: 620 MLGGDMFXXXXXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLR 757
GG F IAPL +K+ LP+G LR
Sbjct: 228 EYGGKYFYFYALIFVLIVIFLMMLIYPNFIAPLFNKYEELPEGDLR 273
>UniRef50_Q5CLH9 Cluster: CAAX prenyl protease; n=3;
Cryptosporidium|Rep: CAAX prenyl protease -
Cryptosporidium hominis
Length = 432
Score = 82.2 bits (194), Expect = 1e-14
Identities = 63/219 (28%), Positives = 99/219 (45%), Gaps = 7/219 (3%)
Frame = +2
Query: 119 ILLFTWVEYLWEQYLSLRQLKIYKTNNTIPE-------DLKEMLNEDLFKKARLYGIDKA 277
I L ++YL Y+ LRQ K Y IP+ D E+ NE+ FKK++ Y K
Sbjct: 13 IFLINLIKYLLYLYVDLRQKKCYDIKE-IPKYILDAYKDCGEVSNEE-FKKSQSYSNSKM 70
Query: 278 QFKIVKELYSTILTSVILYNKWIYVAWRKSEQIGAMFNISPDREIIISCIFMTFITLFNF 457
F ++ + ++ V ++ YV + +I ++ E + S +F + L ++
Sbjct: 71 VFGLISRAVTFVINWVFVF----YVIYPLMWEI--IYTRISSNEYVSSLLFCGVMMLLDY 124
Query: 458 IVNKPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLGGDM 637
++ F +Y FVLEE++GFN T++ FI DQIKS L V +ISV IYI G
Sbjct: 125 PISLAFDLYYTFVLEEKYGFNNSTLKIFIMDQIKSGLLVSVFGTILISVMIYIANNTGKY 184
Query: 638 FXXXXXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSL 754
F I P+ +K P+ + L
Sbjct: 185 FYVYIALVQFGFIFIISIIYPIIIVPIFNKLTPVENQEL 223
>UniRef50_Q11VA2 Cluster: Zn-dependent protease with chaperone
function; n=1; Cytophaga hutchinsonii ATCC 33406|Rep:
Zn-dependent protease with chaperone function -
Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)
Length = 418
Score = 80.2 bits (189), Expect = 5e-14
Identities = 51/223 (22%), Positives = 105/223 (47%)
Frame = +2
Query: 95 DEXAILYLILLFTWVEYLWEQYLSLRQLKIYKTNNTIPEDLKEMLNEDLFKKARLYGIDK 274
D I YLI+ ++L E+ L L I + +P ++ ++ + + +++ Y +K
Sbjct: 2 DAITIKYLIIGILIFDFLVERILDY--LNIKNLSAALPSNVADVYDTAEYNRSQEYQKEK 59
Query: 275 AQFKIVKELYSTILTSVILYNKWIYVAWRKSEQIGAMFNISPDREIIISCIFMTFITLFN 454
+ + + + L ++L ++ + + ++S + +F + + +
Sbjct: 60 EKAEQFQSYFQFALYILLLTQGYLGGLYDYIQASVLQSSLSTYSFYASNLLFFGVLFIAS 119
Query: 455 FIVNKPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLGGD 634
+++ PF+IY FV+EE++GFNK TV+ FI D+IK L++++ II++ +++I
Sbjct: 120 DLISTPFSIYNTFVIEEKYGFNKSTVKLFIMDKIKGYLLAIILGGVIIALLLFLIQTLDT 179
Query: 635 MFXXXXXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLRTA 763
F + PL +K PL DG L+TA
Sbjct: 180 SFWWIFWLIISVLIVTLNMFYTSLLLPLFNKLTPLGDGELKTA 222
>UniRef50_A7HAH2 Cluster: Ste24 endopeptidase; n=2;
Anaeromyxobacter|Rep: Ste24 endopeptidase -
Anaeromyxobacter sp. Fw109-5
Length = 422
Score = 78.2 bits (184), Expect = 2e-13
Identities = 52/217 (23%), Positives = 96/217 (44%)
Frame = +2
Query: 107 ILYLILLFTWVEYLWEQYLSLRQLKIYKTNNTIPEDLKEMLNEDLFKKARLYGIDKAQFK 286
+L + L F ++Y E L L L+ +P L +++ +++R Y + +F
Sbjct: 5 VLPVFLAFFLIQYAIETALLLLNLRHVARARGVPAPLAGRVDDATAERSRAYTLANCRFS 64
Query: 287 IVKELYSTILTSVILYNKWIYVAWRKSEQIGAMFNISPDREIIISCIFMTFITLFNFIVN 466
+ + + LT +L + + + + G R ++ F+ ++L +
Sbjct: 65 LAQGAFFAALTLAVLLSGVLPLLDGALAERGVR---GAHRFVL----FLALVSLAFSVAG 117
Query: 467 KPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLGGDMFXX 646
PF ++ FVLEER GFN+ T R ++ D++KSL L + +P++ + G ++
Sbjct: 118 LPFAVFHTFVLEERFGFNRTTPRLWLTDRLKSLLLQAALGIPLLYATYGFMRFTGALWWV 177
Query: 647 XXXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLR 757
IAPL ++F PLPDG LR
Sbjct: 178 WLFAFYAAVQLVLLWLYPSVIAPLFNRFEPLPDGPLR 214
>UniRef50_A3LZ17 Cluster: Predicted protein; n=2; Pichia
stipitis|Rep: Predicted protein - Pichia stipitis
(Yeast)
Length = 452
Score = 77.8 bits (183), Expect = 3e-13
Identities = 62/222 (27%), Positives = 102/222 (45%), Gaps = 6/222 (2%)
Frame = +2
Query: 110 LYLILLFTWVEYLWEQYLSLRQLKIYKTNNTIPEDLKEMLNEDLFKKARLYGIDKAQFKI 289
L L LL T +Y+++ YL RQ ++ + +IP +K ++ + F+K+ Y I K + +
Sbjct: 20 LVLGLLSTG-KYVFDTYLKYRQYEVLQ-QKSIPASIKAEIDPNDFEKSTDYNIAKLKLSV 77
Query: 290 VKELYS------TILTSVILYNKWIYVAWRKSEQIGAMFNISPDREIIISCIFMTFITLF 451
Y TI T+ I Y+ W S I + I S F T I+L
Sbjct: 78 FNNTYYLFQRLFTIRTN-IFYSLWQTTGLLMSRAIPFLPQFMKGT-ITHSLFFYTTISLI 135
Query: 452 NFIVNKPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLGG 631
+ I++ PF+ Y FV+EE+ GFNKQT+ +++D I L+ VI ++S + + + G
Sbjct: 136 SEIIDLPFSYYREFVVEEKFGFNKQTIGLWLRDHIVGFALNTVIVNGVLSGLLKVFEIYG 195
Query: 632 DMFXXXXXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLR 757
+ F I L K+ PL D +L+
Sbjct: 196 ESF-IVYATGFLFAVSLAFFSLSPFIGRLFHKYTPLQDENLK 236
>UniRef50_Q6ANN7 Cluster: Related to CAAX prenyl protease; n=1;
Desulfotalea psychrophila|Rep: Related to CAAX prenyl
protease - Desulfotalea psychrophila
Length = 412
Score = 76.6 bits (180), Expect = 6e-13
Identities = 53/216 (24%), Positives = 98/216 (45%)
Frame = +2
Query: 110 LYLILLFTWVEYLWEQYLSLRQLKIYKTNNTIPEDLKEMLNEDLFKKARLYGIDKAQFKI 289
L LI++F + E L+L L+ +P+ ++ + D ++ + LY + +
Sbjct: 5 LALIVIFLITTWFLETILTLLNLRNQPAQ--LPKKFADIYSPDKYQDSLLYNKATTRCSL 62
Query: 290 VKELYSTILTSVILYNKWIYVAWRKSEQIGAMFNISPDREIIISCIFMTFITLFNFIVNK 469
+++ ST+L+ L + + +QI EII +F+ + L FI+
Sbjct: 63 LEKTTSTLLSLGFL----LLGGFNALDQIARRGGYG---EIITGLLFIGLLLLVFFIIGL 115
Query: 470 PFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLGGDMFXXX 649
PF +Y FV+EE GFN+ T++ F +D IK+ L++++ P ++ + + G
Sbjct: 116 PFQLYSTFVIEEGFGFNRTTLKTFAEDTIKACLLAIILGGPFLAAIFWFFLKAGPHAWIY 175
Query: 650 XXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLR 757
I PL +KF PL +GSL+
Sbjct: 176 CWLGTTLFSFCLQLLAPTLIMPLFNKFSPLQEGSLK 211
>UniRef50_A2E2V6 Cluster: Clan MA, family M48, Ste24
endopeptidase-like metallopeptidase; n=1; Trichomonas
vaginalis G3|Rep: Clan MA, family M48, Ste24
endopeptidase-like metallopeptidase - Trichomonas
vaginalis G3
Length = 410
Score = 76.2 bits (179), Expect = 8e-13
Identities = 55/206 (26%), Positives = 89/206 (43%)
Frame = +2
Query: 137 VEYLWEQYLSLRQLKIYKTNNTIPEDLKEMLNEDLFKKARLYGIDKAQFKIVKELYSTIL 316
++ +E YL RQ + PE KE +D F AR Y ++K+ FKI++ LY +
Sbjct: 12 IQTQFEAYLHRRQYMKIIGSTEAPEIFKEFYTQDEFSAAREYEMEKSFFKIIQTLYLGFV 71
Query: 317 TSVILYNKWIYVAWRKSEQIGAMFNISPDREIIISCIFMTFITLFNFIVNKPFTIYGVFV 496
++++ I W+ +S E I S IF+ + + P Y FV
Sbjct: 72 --LVIFVMIIAKIWKI---------LSICNEYIRSIIFVIILAILFLGFQIPMKYYNTFV 120
Query: 497 LEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLGGDMFXXXXXXXXXXXX 676
+E++HGFN T+ FI+DQ+ L + +V + ++ + ++I G F
Sbjct: 121 IEQKHGFNNSTLGLFIRDQVTVLGIVIVEFVILVPIFMFIYKKTGKAFIPIGCLIYVLII 180
Query: 677 XXXXXXXXXXIAPLXDKFVPLPDGSL 754
I PL K PL G L
Sbjct: 181 IIHQLIFPTIIYPLFTKLTPLEKGEL 206
>UniRef50_Q1Q610 Cluster: Similar to CAAX prenyl protease 1; n=1;
Candidatus Kuenenia stuttgartiensis|Rep: Similar to CAAX
prenyl protease 1 - Candidatus Kuenenia stuttgartiensis
Length = 421
Score = 75.4 bits (177), Expect = 1e-12
Identities = 50/213 (23%), Positives = 94/213 (44%), Gaps = 2/213 (0%)
Frame = +2
Query: 125 LFTWVEYLWEQYLSLRQLKIYKTNNTIPEDLKEMLNEDLFKKARLYGIDKAQFKIVKELY 304
+F + W YL+L LK K N IP D + ++++L K + Y I+ +F V L+
Sbjct: 13 IFVVIAGYWLDYLNLSHLK--KHGNKIPPDFEGYIDQELLNKTQRYVIENTKFNFVSSLF 70
Query: 305 STILTSVILYNKWI--YVAWRKSEQIGAMFNISPDREIIISCIFMTFITLFNFIVNKPFT 478
+ L+ + Y +W S ++ I+ +F + + ++ PF
Sbjct: 71 HNAILLAFLFGGLLDSYNSWIVSLKMPF---------IVSGLVFFLILLYADTVLMIPFK 121
Query: 479 IYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLGGDMFXXXXXX 658
+Y FV+E ++GF T++ +I D KSL ++ ++ II+ +I+ ++
Sbjct: 122 LYHTFVIENKYGFTTTTMKLWITDLWKSLLITTIMVSFIIATGFFIVQASPGLWWFWIWC 181
Query: 659 XXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLR 757
IAP+ + F P+ D SL+
Sbjct: 182 FFLLFSILMMYIFPYVIAPIFNTFTPVEDESLQ 214
>UniRef50_A1AWN1 Cluster: Ste24 endopeptidase; n=2; sulfur-oxidizing
symbionts|Rep: Ste24 endopeptidase - Ruthia magnifica
subsp. Calyptogena magnifica
Length = 416
Score = 74.9 bits (176), Expect = 2e-12
Identities = 57/230 (24%), Positives = 112/230 (48%), Gaps = 5/230 (2%)
Frame = +2
Query: 86 MNFDEXAILYLILLFTWV-EYLWEQYLSLRQLKIY-KTNNTIPEDLKEMLNEDLFKKARL 259
M F+ +++LI F++V LW L++RQ K+ ++ + IP + ++ + + +KA
Sbjct: 1 MKFNLFTLIFLIATFSYVITLLW---LNVRQSKVVIQSFDKIPNEFRKKITLEEHQKAAK 57
Query: 260 YGIDKAQFKIVKELYSTILTSVILYNKWIYVAWRKSEQIGAMFNI--SPDREIIISCI-F 430
Y Q K+ + I ++ +L + W + + NI + I+ + + F
Sbjct: 58 Y----TQAKLKLNYFEIIFSTAVL------LLWTLGGGLNYLDNIWQAQINNILYTGVGF 107
Query: 431 MTFITLFNFIVNKPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAI 610
+ + + +++ PF+IY FVLE++ FN+ + FI D +K + L L+I LP+I +
Sbjct: 108 VISLMVIGSLIDLPFSIYRTFVLEQKFKFNQTDTKTFIMDLLKGVLLMLIIGLPLIFAIL 167
Query: 611 YIIMLGGDMFXXXXXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLRT 760
Y++ + G+ + IAP+ +KF PL + L+T
Sbjct: 168 YLMSVMGEYWWIYVWLVFTGFLLLIFWLYPIYIAPIFNKFKPLDNVELKT 217
>UniRef50_UPI0000498A37 Cluster: CAAX prenyl protease; n=1;
Entamoeba histolytica HM-1:IMSS|Rep: CAAX prenyl
protease - Entamoeba histolytica HM-1:IMSS
Length = 416
Score = 74.5 bits (175), Expect = 3e-12
Identities = 44/170 (25%), Positives = 88/170 (51%), Gaps = 4/170 (2%)
Frame = +2
Query: 119 ILLFTWVEYLWEQYLSLRQLKIYKTNNTIPEDLKEMLNEDL----FKKARLYGIDKAQFK 286
I++ T + L+E Y RQ K+Y IP D+KE+ + + F+K++ Y ++ ++
Sbjct: 8 IIVLTILTTLFELYKHYRQHKLYYIKE-IPTDVKEVYGDSIEQKEFEKSQNYHLELSKVS 66
Query: 287 IVKELYSTILTSVILYNKWIYVAWRKSEQIGAMFNISPDREIIISCIFMTFITLFNFIVN 466
++ S I+ +L + + + W ++N + + S IF+ + I++
Sbjct: 67 FIRLTISFIINMYVLCSPILRIIW----DFSTIYN-----QFLTSIIFIIIFDFISTIIS 117
Query: 467 KPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYI 616
PF +Y F++ E++G N ++ FIKD IKS L ++ L II++ ++
Sbjct: 118 IPFKLYTTFIIREKYGMNNMSLIVFIKDFIKSFILETILNLIIITLLYFV 167
>UniRef50_Q4DXY8 Cluster: CAAX prenyl protease 1, putative; n=8;
Trypanosoma|Rep: CAAX prenyl protease 1, putative -
Trypanosoma cruzi
Length = 428
Score = 74.1 bits (174), Expect = 3e-12
Identities = 51/203 (25%), Positives = 93/203 (45%), Gaps = 2/203 (0%)
Frame = +2
Query: 149 WEQYLSLRQLKIYKTNNTIPEDLKEMLNEDLFKKARLYGIDKAQFKIVKELYSTILTSVI 328
WE YL RQ + + +PE ++ ++ F+K++ YG DK F I ++ IL++V
Sbjct: 23 WELYLLYRQWRSF-FREELPESHAGIVEDEEFQKSQAYGRDKGAFAICCDVRDLILSNVA 81
Query: 329 LYNKWIYVAWRKSEQIGAMFNISPDREIIISCIFMTFIT-LFNFIVNKPFTIYGVFVLEE 505
+ I + R + + ++ C +T T + + +++ PF Y FV+EE
Sbjct: 82 IL---IRLPARTFDWVAKWLPVAAGS--FTHCCALTAATDVASTLMSLPFDYYKTFVIEE 136
Query: 506 RHGFNKQTVRFFIKDQIKSLFLSLVITLPIIS-VAIYIIMLGGDMFXXXXXXXXXXXXXX 682
+HGFNK + + F KD K L L + + P+ + + + ++ GD F
Sbjct: 137 KHGFNKTSRKEFFKDAAKGLCLRVFLLHPLTTGLILQVVWRFGDRFPLYLFLGATGLAMA 196
Query: 683 XXXXXXXXIAPLXDKFVPLPDGS 751
I PL + + P+ + S
Sbjct: 197 FTFLYPTLIQPLFNTYTPISEDS 219
>UniRef50_Q75D60 Cluster: ABR163Wp; n=1; Eremothecium gossypii|Rep:
ABR163Wp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 453
Score = 73.7 bits (173), Expect = 4e-12
Identities = 54/211 (25%), Positives = 96/211 (45%), Gaps = 3/211 (1%)
Frame = +2
Query: 140 EYLWEQYLSLRQLKIYKTNN-TIPEDLKEMLNEDLFKKARLYGIDKAQFKIVKELYSTIL 316
++ +E YL+ R+ K K N ++P +L+ +++++ +K + Y K ++++V++L L
Sbjct: 29 QFGFETYLATREYK--KLNELSLPSELEGVIDKETMQKTQAYERAKLRYRMVRDLVFLGL 86
Query: 317 TSVILYNKWIYVAWRKSEQIGAMFN--ISPDREIIISCIFMTFITLFNFIVNKPFTIYGV 490
V++ W+ W +G + P I S F+ N+ + Y
Sbjct: 87 NLVMIKYDWLPRMWNLGVAVGQRMPAMLVPVSTISQSLYFLIVYLQLNWWQGLFGSYYYN 146
Query: 491 FVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLGGDMFXXXXXXXXXX 670
FVLEE+ GFNK TV+ ++ DQ+K +S +IT P + +I F
Sbjct: 147 FVLEEKFGFNKSTVKLWLTDQLKVFMISSMITTPAAYALLKVIEKFSTGFVSYVSILMLF 206
Query: 671 XXXXXXXXXXXXIAPLXDKFVPLPDGSLRTA 763
A L +K PL DG L+T+
Sbjct: 207 FYLVLTALQPVFTA-LFNKLTPLEDGELKTS 236
>UniRef50_Q54M80 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 484
Score = 72.5 bits (170), Expect = 1e-11
Identities = 49/185 (26%), Positives = 99/185 (53%), Gaps = 16/185 (8%)
Frame = +2
Query: 113 YLILLFTWVEYLWEQYLSLRQLKIYKTNNTIPEDLK--------EMLN-EDLFKKARLYG 265
Y+ L+ ++ Y+ YL+ RQ+K K N+ IP++ K E LN + L + Y
Sbjct: 5 YICLINVFINYIILLYLNFRQIKTIK-NSKIPKEFKNLSIINKSEFLNLKQLKYNLKFYF 63
Query: 266 IDKAQ------FKIVKELYSTILTSVILYNKWIY-VAWRKSEQIGAMFNISPDREIIISC 424
I K + FK + LYS I S++++ ++Y + W S + ++ N EI+ +
Sbjct: 64 IKKKKKKKKRIFKFISTLYSFI--SLLVFILYLYPLLWNFSNNLSSIDNNPLKDEIVATI 121
Query: 425 IFMTFITLFNFIVNKPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISV 604
+F + + + I+N P + Y FVL + FN + ++ F++D+ ++ ++I +P++++
Sbjct: 122 VFFSIKSFLSLILNFPISYYQTFVLTDE--FNSRNIKLFLQDKALNVIFLVIIYIPLVTL 179
Query: 605 AIYII 619
+I +I
Sbjct: 180 SITVI 184
>UniRef50_UPI0000E49E55 Cluster: PREDICTED: hypothetical protein,
partial; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: hypothetical protein, partial -
Strongylocentrotus purpuratus
Length = 87
Score = 72.1 bits (169), Expect = 1e-11
Identities = 29/72 (40%), Positives = 45/72 (62%)
Frame = +2
Query: 107 ILYLILLFTWVEYLWEQYLSLRQLKIYKTNNTIPEDLKEMLNEDLFKKARLYGIDKAQFK 286
I + I F W+ Y+WE YLS RQ +Y+ +P LK++++ + F+KARLYG+DK+ F
Sbjct: 16 IFWAIFTFMWIVYVWETYLSHRQRNVYRNTKDVPSSLKDVIDNETFEKARLYGLDKSSFG 75
Query: 287 IVKELYSTILTS 322
+Y I +S
Sbjct: 76 FWHGIYEQIESS 87
>UniRef50_Q4FYW8 Cluster: Metallo-peptidase, Clan M-, Family M48;
n=3; Leishmania|Rep: Metallo-peptidase, Clan M-, Family
M48 - Leishmania major strain Friedlin
Length = 427
Score = 71.3 bits (167), Expect = 2e-11
Identities = 47/199 (23%), Positives = 93/199 (46%), Gaps = 1/199 (0%)
Frame = +2
Query: 146 LWEQYLSLRQLKIYKTNNTIPEDLKEMLNEDLFKKARLYGIDKAQFKIVKELYSTILTSV 325
+W+ YL LRQ + +T +P ++ + ++ F KA+ Y +K+ F ++ L +LT++
Sbjct: 21 MWDAYLVLRQRRANQTKE-MPSYFRKDITDEEFAKAKEYESEKSTFSFLQHLKGLVLTNM 79
Query: 326 ILYNKWIYVAWRKSEQIGAMFNISPDREIIISCIFMTFITLFNFIVNKPFTIYGVFVLEE 505
++ + + + Q ++ S + L + +++ PF+ Y F +E+
Sbjct: 80 GIFLRLPALLYYLVAQRASLSTGSFSHNYAAAVAG----ELISVVLDIPFSYYENFHIED 135
Query: 506 RHGFNKQTVRFFIKDQIKSLFLSLVITLPI-ISVAIYIIMLGGDMFXXXXXXXXXXXXXX 682
RHG N+ T F+KD +K+L L + + P+ I + +++ G+ F
Sbjct: 136 RHGLNEMTKTEFVKDIVKTLLLRVTLLYPMQIKLIQFVVQRFGERFPLYLFFGMSVMLVV 195
Query: 683 XXXXXXXXIAPLXDKFVPL 739
I PL +KF PL
Sbjct: 196 FLLAMPTVIQPLFNKFTPL 214
>UniRef50_A7D065 Cluster: Ste24 endopeptidase; n=1; Opitutaceae
bacterium TAV2|Rep: Ste24 endopeptidase - Opitutaceae
bacterium TAV2
Length = 436
Score = 69.3 bits (162), Expect = 1e-10
Identities = 48/225 (21%), Positives = 102/225 (45%), Gaps = 7/225 (3%)
Frame = +2
Query: 107 ILYLILLFTWVEYLWEQYLS-LRQLKIYKTNNTIPEDLKEMLNEDLFKKARLYGIDKAQF 283
+L ++L+ V + + LS L + ++ + + P + +++ + ++K+ Y + K +F
Sbjct: 10 VLPVVLVLIAVRLVAQLVLSALNRAEVRRHAHAAPPAVAAVVDAETYQKSVAYTLVKNRF 69
Query: 284 KIVKELYSTILTSVILYN---KWIY---VAWRKSEQIGAMFNISPDREIIISCIFMTFIT 445
+++ ++ +L V+L + W+Y +AW G + +F+
Sbjct: 70 GVIELIFDAVLLVVVLTSGVLPWLYDLVMAWAPDAGEGG----GGGWNSALGAVFILVAG 125
Query: 446 LFNFIVNKPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIML 625
+ + P + F +E R GFNK T+ +I D++K + L+LVI ++ + ++ +
Sbjct: 126 ILLSLPGLPLDWWDTFRIETRFGFNKSTLGLWIVDKVKGMLLALVIGFLLLWALLALVRV 185
Query: 626 GGDMFXXXXXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLRT 760
G ++ I PL +K PLP+G LRT
Sbjct: 186 AGSLWWVWGFALFFGFQLLMMVLYPRLIVPLFNKLTPLPEGELRT 230
>UniRef50_Q8IHA2 Cluster: AT22982p; n=3; Sophophora|Rep: AT22982p -
Drosophila melanogaster (Fruit fly)
Length = 456
Score = 68.5 bits (160), Expect = 2e-10
Identities = 55/224 (24%), Positives = 98/224 (43%), Gaps = 2/224 (0%)
Frame = +2
Query: 95 DEXAILYLILLFTWVEYLWEQYLSLRQLKI-YKTNNTIPEDLKEMLNEDLFKKARLYGID 271
D AILY+I+ F ++ LW YL LR +++ YKT +P + L ++L+ K R+Y I
Sbjct: 17 DPLAILYIIIAFLVLDNLWGVYLMLRDIQVAYKTQQ-VPNVISPYLPQELYDKMRVYKIH 75
Query: 272 KAQFKIVKELYSTILTSVI-LYNKWIYVAWRKSEQIGAMFNISPDREIIISCIFMTFITL 448
K F IV L S ++ ++ LY + + AW + + E +S IF+ +++
Sbjct: 76 KGWFTIVNTLLSAVILGIMELY--FGFYAWLYGVAGKCALSKWMEHEACVSVIFVLLLSV 133
Query: 449 FNFIVNKPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLG 628
+ ++ + P IY ++ K I + L + +IT ++ +Y+ +
Sbjct: 134 YFWLKSVPAMIYESCCIKSLQPRPKPPWWSRICHFVVDLVVGAMITTLVVVALVYMFIGL 193
Query: 629 GDMFXXXXXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLRT 760
G I P + VPL + +LRT
Sbjct: 194 GPYAPLGLYLQSLILTMIVLLLIPFMIHPFVGQSVPLENSNLRT 237
>UniRef50_A6Q3T8 Cluster: Zinc-metallo protease; n=2;
Epsilonproteobacteria|Rep: Zinc-metallo protease -
Nitratiruptor sp. (strain SB155-2)
Length = 418
Score = 67.3 bits (157), Expect = 4e-10
Identities = 41/122 (33%), Positives = 57/122 (46%)
Frame = +2
Query: 392 ISPDREIIISCIFMTFITLFNFIVNKPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFL 571
I D +I S +++ N++V PF IY FVL+E GFNK T+ FIKDQIK L
Sbjct: 82 IQIDDILIKSVVYIDLFFAINYLVTLPFDIYQKFVLDEEFGFNKSTISLFIKDQIKMALL 141
Query: 572 SLVITLPIISVAIYIIMLGGDMFXXXXXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGS 751
LV ++ + + IML + IAP+ +KF PL D
Sbjct: 142 FLVFASILVYIVGW-IMLHVSNWWIWGFVFIFSVIILINAIYPTLIAPMFNKFTPLQDEE 200
Query: 752 LR 757
L+
Sbjct: 201 LK 202
>UniRef50_A1ZZ74 Cluster: Caax prenyl protease 1; n=1; Microscilla
marina ATCC 23134|Rep: Caax prenyl protease 1 -
Microscilla marina ATCC 23134
Length = 393
Score = 67.3 bits (157), Expect = 4e-10
Identities = 46/187 (24%), Positives = 81/187 (43%)
Frame = +2
Query: 203 IPEDLKEMLNEDLFKKARLYGIDKAQFKIVKELYSTILTSVILYNKWIYVAWRKSEQIGA 382
+P++L+ + + ++++ Y F + S ++T +++ V +E +
Sbjct: 13 LPQELEGLYTNEEYQRSLAYKKAVGHFSLFTGTLSFVVTLMLIVTGGFAVV---AEWVNG 69
Query: 383 MFNISPDREIIISCIFMTFITLFNFIVNKPFTIYGVFVLEERHGFNKQTVRFFIKDQIKS 562
N I + +F + L N ++ PF +Y FV+EER GFNK T + FI D++K
Sbjct: 70 QVN----HPIGQTMVFFAVLMLANNVLTLPFQLYSTFVIEERFGFNKITPKTFIIDKVKG 125
Query: 563 LFLSLVITLPIISVAIYIIMLGGDMFXXXXXXXXXXXXXXXXXXXXXXIAPLXDKFVPLP 742
L V+ + +Y+I F I PL +KF PL
Sbjct: 126 YILGGVLGGALGFAFLYLIAQMQQQFWVYFWVVIAVFMVFMNMFYTSLIMPLFNKFTPLE 185
Query: 743 DGSLRTA 763
+G LRT+
Sbjct: 186 EGELRTS 192
>UniRef50_A4CQ25 Cluster: Caax prenyl protease 1; n=3;
Flavobacteriaceae|Rep: Caax prenyl protease 1 -
Robiginitalea biformata HTCC2501
Length = 415
Score = 66.9 bits (156), Expect = 5e-10
Identities = 54/218 (24%), Positives = 93/218 (42%)
Frame = +2
Query: 104 AILYLILLFTWVEYLWEQYLSLRQLKIYKTNNTIPEDLKEMLNEDLFKKARLYGIDKAQF 283
A+ YLI+ ++YL + L L + N PE++ ++ N + ++K + Y +F
Sbjct: 5 ALYYLIIGILILDYLADTLLEY--LNARRFGNPPPEEVADLYNREAYEKTQSYNRANYRF 62
Query: 284 KIVKELYSTILTSVILYNKWIYVAWRKSEQIGAMFNISPDREIIISCIFMTFITLFNFIV 463
S + T L W + I +IS D I + +F + L ++
Sbjct: 63 GFAASTASLLATLGFLVFGGF--GWLDTLAI----SISQD-PIGQALVFFGLLFLGGELI 115
Query: 464 NKPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLGGDMFX 643
PF+ Y FV+EER GFNKQTV F D++K L++++ ++++ + G F
Sbjct: 116 GLPFSWYRTFVIEERFGFNKQTVALFWADKLKGWALAMILGGGLLALVMVFYRWAGPGFW 175
Query: 644 XXXXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLR 757
PL ++ PL DG L+
Sbjct: 176 IYAWLLIGVFTVLTNLLYSRVFVPLFNRQEPLEDGPLK 213
>UniRef50_Q7JV41 Cluster: AT28654p; n=2; Sophophora|Rep: AT28654p -
Drosophila melanogaster (Fruit fly)
Length = 456
Score = 66.1 bits (154), Expect = 9e-10
Identities = 46/183 (25%), Positives = 90/183 (49%), Gaps = 1/183 (0%)
Frame = +2
Query: 95 DEXAILYLILLFTWVEYLWEQYLSLRQLKIYKTNNTIPEDLKEMLNEDLFKKARLYGIDK 274
D +L ++ L V+ +WE L+ RQ + +PE+L+ ++ +++ +AR+Y + K
Sbjct: 11 DPIIVLVVLCLIVLVDRIWEMILTKRQQLVCLNAIMVPEELRGIIPPEIYHRARIYELHK 70
Query: 275 AQFKIVKELYSTILTSVILYNKWIYVAWRKSEQIGAMFNISPDREIIISCIFMTFITLFN 454
+ +I K L I+T L + W S + + I+ +EI I+ IF+ ++T++
Sbjct: 71 TELQIWKYLIDLIITLCELILGFYPFLWSLSAK--TLQKIT-SQEIWITLIFVFYLTIYI 127
Query: 455 FIVNKPFTIYGVFVLEERHGFN-KQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLGG 631
I P IY +LE R+G + K + S+ LS ++ P+ + ++ + G
Sbjct: 128 CIRFLPVLIYDKCLLELRYGMSGKFPWYLYCCIGAMSILLSQLVLFPLAAAIVFSVKFIG 187
Query: 632 DMF 640
F
Sbjct: 188 YYF 190
>UniRef50_A0L612 Cluster: Ste24 endopeptidase precursor; n=2;
cellular organisms|Rep: Ste24 endopeptidase precursor -
Magnetococcus sp. (strain MC-1)
Length = 410
Score = 64.5 bits (150), Expect = 3e-09
Identities = 31/111 (27%), Positives = 55/111 (49%)
Frame = +2
Query: 425 IFMTFITLFNFIVNKPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISV 604
IF+ + ++ P T+Y F +E R+GFN+ T+ F+KD++K L L+L++ P+++
Sbjct: 104 IFIGTLLATTALLGLPGTLYSTFSIENRYGFNRTTLATFLKDRLKGLLLTLLLGGPLLAA 163
Query: 605 AIYIIMLGGDMFXXXXXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLR 757
+ GD I PL ++F PLP+G+L+
Sbjct: 164 LLLFFQWAGDWGWLYAWGMLTVVSLFIQYVAASWIMPLFNRFDPLPEGALK 214
>UniRef50_A0LI27 Cluster: Ste24 endopeptidase precursor; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: Ste24
endopeptidase precursor - Syntrophobacter fumaroxidans
(strain DSM 10017 / MPOB)
Length = 435
Score = 63.7 bits (148), Expect = 5e-09
Identities = 48/196 (24%), Positives = 91/196 (46%), Gaps = 1/196 (0%)
Frame = +2
Query: 161 LSLRQLKIYKTNNTIPEDLKEMLNEDLFKKARLYGIDKAQFKIVKELYS-TILTSVILYN 337
L+LR +K K + +P + ++E ++ Y +++ V+E+ T+L +VI+
Sbjct: 28 LNLRFMK--KHGSGVPTSFEGFIDEATLARSNAYAAARSRLGTVQEVVGQTVLLAVIVSG 85
Query: 338 KWIYVAWRKSEQIGAMFNISPDREIIISCIFMTFITLFNFIVNKPFTIYGVFVLEERHGF 517
V Q + NI+ +F+ L + + + PF + FV+E+++GF
Sbjct: 86 --FLVGLEGQIQQWKLGNIAG------GLLFLLVPALISAVADLPFDYHETFVIEQKYGF 137
Query: 518 NKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLGGDMFXXXXXXXXXXXXXXXXXXX 697
N+ TVR ++ D +KS ++LV+ + ++S I I+ D +
Sbjct: 138 NRSTVRLWVTDHVKSAAIALVLFVVLVSPLIRIMDTAPDTWWFWGFLVVSAVQVLLVVLY 197
Query: 698 XXXIAPLXDKFVPLPD 745
IAPL +KF P+ D
Sbjct: 198 PLFIAPLFNKFEPVRD 213
>UniRef50_A1WB44 Cluster: Ste24 endopeptidase precursor; n=57;
Proteobacteria|Rep: Ste24 endopeptidase precursor -
Acidovorax sp. (strain JS42)
Length = 437
Score = 62.9 bits (146), Expect = 8e-09
Identities = 48/201 (23%), Positives = 90/201 (44%), Gaps = 1/201 (0%)
Frame = +2
Query: 158 YLSLRQLK-IYKTNNTIPEDLKEMLNEDLFKKARLYGIDKAQFKIVKELYSTILTSVILY 334
+L+ RQ++ + + +P + +KA Y I KA+F +++ + T+V+L
Sbjct: 32 WLATRQIRHVAQHRGAVPTAFAHRIPLAAHQKAADYTIAKARFGLLE---MALATAVVL- 87
Query: 335 NKWIYVAWRKSEQIGAMFNISPDREIIISCIFMTFITLFNFIVNKPFTIYGVFVLEERHG 514
W + + + + ++ + L ++ P +Y FV+E+R G
Sbjct: 88 -GWTLLGGLDALNQALLSWLGGG--MLQQLALLACFVLIGGAIDLPVALYQTFVIEQRFG 144
Query: 515 FNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLGGDMFXXXXXXXXXXXXXXXXXX 694
FN+ T R ++ D +KS L VI LPI ++ ++++ G ++
Sbjct: 145 FNQMTPRLWLADLLKSTLLGAVIGLPIAALILWLMGAAGPLWWLWAWGTWMGFNLLLMVV 204
Query: 695 XXXXIAPLXDKFVPLPDGSLR 757
IAPL +KF PL D SL+
Sbjct: 205 FPLFIAPLFNKFQPLEDESLK 225
>UniRef50_A0E1K7 Cluster: Chromosome undetermined scaffold_73, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_73,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 427
Score = 62.9 bits (146), Expect = 8e-09
Identities = 48/222 (21%), Positives = 100/222 (45%), Gaps = 4/222 (1%)
Frame = +2
Query: 110 LYLILLFTWVEYLWEQYLSLRQLKIYKTNNTIPEDLKEML--NEDLFKKARLYGIDKAQF 283
LY+++ + ++YL EQ+++LRQL +P +++ L + FK+++ + DK F
Sbjct: 16 LYIVVSYIVIKYLLEQFINLRQLDQLSVKQ-MPIHIEQTLGITQKQFKRSQRFYYDKLSF 74
Query: 284 KIVKELYSTILTSVILYNKWIYVAWRKSEQIGAMFNISPDREII--ISCIFMTFITLFNF 457
++ + T + +++ + W E+ F + P+ E ++ IF+ F+ L
Sbjct: 75 EMYTKSIKTAIEIIVILCGVMPFIW---ERTVTFFKMDPNSEFQRGLAYIFVEFLRL--K 129
Query: 458 IVNKPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLGGDM 637
+++ P Y V+E+R+ ++ + D + L +V ++ +Y+ LGGD
Sbjct: 130 LIDVPNNFYNTHVIEKRYDLSQISFALQFSDLVIESALWVVFVPILLYSYLYVAELGGDY 189
Query: 638 FXXXXXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLRTA 763
F I PL ++F L + L+ A
Sbjct: 190 FFIAMQFFVLIMAIVSSLVYPNYIQPLFNEFEELKETQLKQA 231
>UniRef50_UPI0000E87B29 Cluster: probable transmembrane protease;
n=1; Methylophilales bacterium HTCC2181|Rep: probable
transmembrane protease - Methylophilales bacterium
HTCC2181
Length = 413
Score = 62.5 bits (145), Expect = 1e-08
Identities = 50/218 (22%), Positives = 98/218 (44%), Gaps = 1/218 (0%)
Frame = +2
Query: 113 YLILLFTWVEYLWEQYLSLRQLK-IYKTNNTIPEDLKEMLNEDLFKKARLYGIDKAQFKI 289
+ I L + L E +L+ RQ+ + K N +P + + + KKA Y + K QF
Sbjct: 8 FFIFLIIFAASL-EFWLNKRQINHVQKNKNKVPVEFSKTIKLRDHKKAADYTVAKTQFGS 66
Query: 290 VKELYSTILTSVILYNKWIYVAWRKSEQIGAMFNISPDREIIISCIFMTFITLFNFIVNK 469
+ ++++ + Y ++ + +E AM + ++ + +TF+ + IV
Sbjct: 67 ----FGLVVSAFVTY--YLTIGGGINEINAAMIDYDVS-SLLGGSLVVTFLAVILSIVEI 119
Query: 470 PFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLGGDMFXXX 649
P +Y +V+EER GFNK + F+ D + L + ++T I+ ++++II G +
Sbjct: 120 PSNLYSTYVIEERFGFNKTKAKTFMSDVLIDLATTALVTFAIMYISLWIISSLGSSW-WV 178
Query: 650 XXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLRTA 763
+ L +KF PL D L+++
Sbjct: 179 WLWVFLSAVVVIMSALAPALQQLKNKFSPLEDKKLKSS 216
>UniRef50_Q6C243 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 478
Score = 62.5 bits (145), Expect = 1e-08
Identities = 56/223 (25%), Positives = 95/223 (42%), Gaps = 17/223 (7%)
Frame = +2
Query: 140 EYLWEQYLSLRQLKIYKTNNTIPEDLKEMLNEDLFKKARLYGIDKAQFKIVKELYSTI-L 316
+YL E YL+ RQ ++YK +P L+ +++++ ++ Y + K +F V YS +
Sbjct: 53 DYLLESYLNYRQYQVYKRTE-VPASLQGIVSQEKLTESNDYSMAKMRFSFVHSTYSLVNF 111
Query: 317 TSVILYN---------KWIYVAWRKSEQIGAMF-------NISPDREIIISCIFMTFITL 448
+ I +N K + + GA F ++ + + F F L
Sbjct: 112 LATIHFNVIPKIFHVTKMGFTKRIAPKLAGATFFGAKTLHKLALSTPVHTAFAFNVF-GL 170
Query: 449 FNFIVNKPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLG 628
+ ++ PF+ Y FVLE+++GFNK T + F+ D K LS I I + I++
Sbjct: 171 VSSLLELPFSYYKNFVLEKKYGFNKMTPKTFVLDFFKEQALSFTIQGLYIGIFEKILIKF 230
Query: 629 GDMFXXXXXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLR 757
G F I P+ +KF L DG L+
Sbjct: 231 GLSFVPYFTGFVVVLQIVLMYAVPTLIMPMFNKFEKLEDGELK 273
>UniRef50_Q4AGI4 Cluster: Ste24 endopeptidase; n=1; Chlorobium
phaeobacteroides BS1|Rep: Ste24 endopeptidase -
Chlorobium phaeobacteroides BS1
Length = 341
Score = 62.1 bits (144), Expect = 1e-08
Identities = 32/115 (27%), Positives = 54/115 (46%)
Frame = +2
Query: 419 SCIFMTFITLFNFIVNKPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPII 598
S +F + L + I++ PF Y FV+EE++GFNK +++ F+ D++K ++ VI ++
Sbjct: 27 SALFFGVLFLVSDILSIPFQYYHTFVIEEKYGFNKSSLKTFVFDKLKGWVITAVIGGGLL 86
Query: 599 SVAIYIIMLGGDMFXXXXXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLRTA 763
++ G+ F I PL +K PLP G L A
Sbjct: 87 MFLLWAFEATGNWFFLIFMSGLTLFSVTISLFYTKLIVPLFNKLTPLPQGELADA 141
>UniRef50_A7I114 Cluster: Peptidase, M48 family; n=2;
Campylobacter|Rep: Peptidase, M48 family - Campylobacter
hominis (strain ATCC BAA-381 / LMG 19568 / NCTC 13146
/CH001A)
Length = 404
Score = 61.7 bits (143), Expect = 2e-08
Identities = 52/220 (23%), Positives = 95/220 (43%), Gaps = 1/220 (0%)
Frame = +2
Query: 107 ILYLILLFTWVEYLWEQYLSLRQLKIYKTNNTIPEDLKEMLNEDLFKKARLYGIDKAQFK 286
+LYL++ + L+ L++ QL K P +LNE +KKA I +F+
Sbjct: 1 MLYLLIFLYAIYSLYRLILAILQLNFVKAKINEPA---VVLNETDYKKAANVAIINQKFQ 57
Query: 287 IVKELYSTILTSVILYNKWIYVAWRKSEQIGAMFNISPDR-EIIISCIFMTFITLFNFIV 463
I Y + L+ W+ + + +FN+ + E++ + + + I+
Sbjct: 58 IFSYFYEFFIA---LF--WLLTGLKILQNF--IFNLGIFKNELLNETLLVLAFLICGAIL 110
Query: 464 NKPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLGGDMFX 643
+ P IY F +++ GF+ T + FI+D IKS L+L+ +I ++ I G +
Sbjct: 111 SLPLNIYEKFYKDKKLGFSNITPKIFIQDSIKSFVLTLIFGGIVIFALLFCIQNLGKFWW 170
Query: 644 XXXXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLRTA 763
IAP+ +K PL +G L+T+
Sbjct: 171 IYGFMLSFILVLIVSLIYPTLIAPIFNKMSPLQNGELKTS 210
>UniRef50_Q2S4T7 Cluster: Caax prenyl protease 1; n=1; Salinibacter
ruber DSM 13855|Rep: Caax prenyl protease 1 -
Salinibacter ruber (strain DSM 13855)
Length = 418
Score = 60.1 bits (139), Expect = 6e-08
Identities = 47/218 (21%), Positives = 91/218 (41%)
Frame = +2
Query: 104 AILYLILLFTWVEYLWEQYLSLRQLKIYKTNNTIPEDLKEMLNEDLFKKARLYGIDKAQF 283
A++ LL +V L L+LR L+ +P + ++ +E +++A+ Y +F
Sbjct: 6 ALILAALLAEYVLNLGSDLLNLRHLQ-----PELPAEFRDTFDEAEYERAQAYTRTTTRF 60
Query: 284 KIVKELYSTILTSVILYNKWIYVAWRKSEQIGAMFNISPDREIIISCIFMTFITLFNFIV 463
+V + + V W + + + + P I ++ + L ++
Sbjct: 61 GLVSSTFGLAVLLVF----WFAGGFEGLDTVVRGWGFGP---IGTGLCYIGLLVLGRGLL 113
Query: 464 NKPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLGGDMFX 643
PF++Y F +EER GFN+ T R F D +KS+ L + + P+++ ++ G
Sbjct: 114 ALPFSLYSTFGIEERFGFNETTPRTFALDLLKSVALGVALGGPLLAAILWFFQSTGPYGW 173
Query: 644 XXXXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLR 757
+ PL + F PL +G+LR
Sbjct: 174 VYAWAVVTAVMLGLQFFAPRYLMPLFNDFEPLEEGALR 211
>UniRef50_A7H4A3 Cluster: Peptidase, M48 family; n=12;
Campylobacter|Rep: Peptidase, M48 family - Campylobacter
jejuni subsp. doylei 269.97
Length = 395
Score = 59.3 bits (137), Expect = 1e-07
Identities = 48/216 (22%), Positives = 92/216 (42%)
Frame = +2
Query: 107 ILYLILLFTWVEYLWEQYLSLRQLKIYKTNNTIPEDLKEMLNEDLFKKARLYGIDKAQFK 286
++ ++ L+T + W Y +R L+ K ++L+E ++ A I+ +FK
Sbjct: 3 LIAILCLYTAL-LSWISYAQIRFLEREKDKQA------QILSEKDYQNAADIAIENEKFK 55
Query: 287 IVKELYSTILTSVILYNKWIYVAWRKSEQIGAMFNISPDREIIISCIFMTFITLFNFIVN 466
+ Y+ I+ WI + +++ N + + +F+ + I+N
Sbjct: 56 LFSNFYNLIINIA-----WISFGFLYLKELLISNNTRFE-----NTLFLLSFLIITSILN 105
Query: 467 KPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLGGDMFXX 646
P +IY F+ ++ HGF+ TV+ FIKD +KSL L+L+ I+ ++ G +
Sbjct: 106 LPLSIYESFIKDKAHGFSNMTVKLFIKDTVKSLILTLIFGFLILYALLFCYDFFGTFWWI 165
Query: 647 XXXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSL 754
IAP+ +K L D +L
Sbjct: 166 VAFIFAFCIIVITNLIYPTLIAPIFNKMEKLNDENL 201
>UniRef50_Q2LYG7 Cluster: Zn-dependent protease with chaperone
function; n=1; Syntrophus aciditrophicus SB|Rep:
Zn-dependent protease with chaperone function -
Syntrophus aciditrophicus (strain SB)
Length = 453
Score = 58.0 bits (134), Expect = 2e-07
Identities = 43/221 (19%), Positives = 96/221 (43%), Gaps = 1/221 (0%)
Frame = +2
Query: 104 AILYLILLFTWVEYLWEQYLSLRQLK-IYKTNNTIPEDLKEMLNEDLFKKARLYGIDKAQ 280
A+L L+ L+++ L+ ++ + +PE + ++E + Y + ++
Sbjct: 41 ALLVTFLILFLARSLFKEALTRINIRHLQHHGRRVPELFRGEIDEATLSRMTDYTVTTSR 100
Query: 281 FKIVKELYSTILTSVILYNKWIYVAWRKSEQIGAMFNISPDREIIISCIFMTFITLFNFI 460
F + + +LT +L + + W G I+ +F + + L + +
Sbjct: 101 FTSFEGIVDDLLTLTVLLSG--VLPWLTGILSGRQLPF-----ILSGLLFFSVLMLASGV 153
Query: 461 VNKPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLGGDMF 640
+ PF +Y +F +E+R+GF+ T R ++ D +KSL +S+++ + S + +I + +
Sbjct: 154 IAVPFDLYRIFGIEKRYGFSTMTFRLWVMDSLKSLGISVILLGALGSAFLALIQYARESW 213
Query: 641 XXXXXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLRTA 763
IAPL +++ P+ D L+ A
Sbjct: 214 WFWSWLLFAAFQLLMLWLYPVVIAPLFNRYEPIQDQDLKRA 254
>UniRef50_Q30UQ0 Cluster: Ste24 endopeptidase precursor; n=1;
Desulfovibrio desulfuricans G20|Rep: Ste24 endopeptidase
precursor - Desulfovibrio desulfuricans (strain G20)
Length = 427
Score = 57.6 bits (133), Expect = 3e-07
Identities = 31/118 (26%), Positives = 56/118 (47%)
Frame = +2
Query: 410 IIISCIFMTFITLFNFIVNKPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITL 589
I+ +F + + + + PF+++ FV EER GFN+ T F+ D++K+ L V+
Sbjct: 108 IMTGLVFFGLLGVLSSLAGLPFSLWRTFVHEERFGFNRTTPLTFVADRLKAGLLVAVMGG 167
Query: 590 PIISVAIYIIMLGGDMFXXXXXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLRTA 763
P+ + ++++ L G + PL + F PLP G+LR+A
Sbjct: 168 PLAAGVLWLLALYGPEAWLPVWLLVSVFSLLVSFLAPRYLLPLFNTFTPLPQGALRSA 225
>UniRef50_UPI00006CFC10 Cluster: Peptidase family M48 containing
protein; n=1; Tetrahymena thermophila SB210|Rep:
Peptidase family M48 containing protein - Tetrahymena
thermophila SB210
Length = 753
Score = 57.2 bits (132), Expect = 4e-07
Identities = 45/188 (23%), Positives = 81/188 (43%), Gaps = 3/188 (1%)
Frame = +2
Query: 203 IPEDLKEM-LNEDLFKKARLYGIDKAQFKIVKELYSTILTSVILYNKWIYVAWRKSEQIG 379
+P D++ + ++ D +K+A Y A F++ T L + + + W ++
Sbjct: 1 MPSDVRSLGIDPDQYKRAMQY----AAFQMYVYSVKTGLECIFSLTYVMPLVWNGVTKLF 56
Query: 380 AMFNISPDREIIISCIFMTFITLFNFIVNKPFTIYGVFVLEERHGFNKQTVRFFIKDQIK 559
+ I P E +F+ L + ++ P +Y FV+EE++GFNK+T+ F D +
Sbjct: 57 PI--IEPTSEFQRGFMFLLIEALKSKFIDVPIALYETFVIEEKYGFNKKTLFLFFNDLVI 114
Query: 560 SLFLSLVITLPIISVAIYII--MLGGDMFXXXXXXXXXXXXXXXXXXXXXXIAPLXDKFV 733
LS++I I+ IY++ + F IAP +KF
Sbjct: 115 EAGLSVIIIPTILYGYIYVVDKTESNEWFFFNVEIFIILFMLAYITINPNFIAPAFNKFE 174
Query: 734 PLPDGSLR 757
L DG L+
Sbjct: 175 ELEDGELK 182
>UniRef50_A6Q7V5 Cluster: Zinc metallopeptidase; n=1; Sulfurovum sp.
NBC37-1|Rep: Zinc metallopeptidase - Sulfurovum sp.
(strain NBC37-1)
Length = 427
Score = 56.8 bits (131), Expect = 5e-07
Identities = 34/119 (28%), Positives = 61/119 (51%), Gaps = 2/119 (1%)
Frame = +2
Query: 275 AQFKIVKELYSTILTSV--ILYNKWIYVAWRKSEQIGAMFNISPDREIIISCIFMTFITL 448
A + + KE I T V +++ W++ + + ++F + D + S F+
Sbjct: 47 ANYAVAKEKLGIIETFVDYLMFLWWVFAGFA---WLSSLFQV--DGGVTSSVFFLFGFVA 101
Query: 449 FNFIVNKPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIML 625
N++V PF++Y F ++E GFNK T + FI D +KS L +V+ + +V +II L
Sbjct: 102 VNYVVGLPFSLYQTFKIDEDFGFNKMTPKTFIVDALKSAGLFIVLGGAVFAVLAWIISL 160
>UniRef50_Q7VGH2 Cluster: Zinc-metallo protease; n=1; Helicobacter
hepaticus|Rep: Zinc-metallo protease - Helicobacter
hepaticus
Length = 408
Score = 56.4 bits (130), Expect = 7e-07
Identities = 55/217 (25%), Positives = 100/217 (46%)
Frame = +2
Query: 107 ILYLILLFTWVEYLWEQYLSLRQLKIYKTNNTIPEDLKEMLNEDLFKKARLYGIDKAQFK 286
++ + LF L L++ Q++ K P L E +ED + +A Y I +
Sbjct: 5 LIIFVGLFICAYALPSIILAILQIRHIKAELQKPAILLE--SED-YHQAGEYAIASLRLD 61
Query: 287 IVKELYSTILTSVILYNKWIYVAWRKSEQIGAMFNISPDREIIISCIFMTFITLFNFIVN 466
I+ + I + IL+ + + +K I +++P + + + ++F+ L + I+
Sbjct: 62 IINRVLEII--TFILWVSFGFSLLQKQLDIFMPHSLNPIWQSV--ALVLSFM-LISSIIE 116
Query: 467 KPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLGGDMFXX 646
P +IY F L+++ GF+KQT + FI D K LSL++ I+ + I+II ++
Sbjct: 117 LPLSIYKTFGLDKKFGFSKQTPKLFIIDLYKHFLLSLIVGGLIVFLLIFIIEKVV-LWWI 175
Query: 647 XXXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLR 757
IAPL +KF PL D +L+
Sbjct: 176 VGFIVLLSVVILANFVYPTLIAPLFNKFTPLDDENLK 212
>UniRef50_Q1JZV6 Cluster: Ste24 endopeptidase; n=6; Bacteria|Rep:
Ste24 endopeptidase - Desulfuromonas acetoxidans DSM 684
Length = 414
Score = 56.4 bits (130), Expect = 7e-07
Identities = 47/221 (21%), Positives = 95/221 (42%), Gaps = 1/221 (0%)
Frame = +2
Query: 104 AILYLILLFTWV-EYLWEQYLSLRQLKIYKTNNTIPEDLKEMLNEDLFKKARLYGIDKAQ 280
+IL+ I++ V +Y E+ + + L +T P +L+++ + + +++ + Y +
Sbjct: 5 SILFTIIVILLVADYALERVVDV--LNSRWMGHTPPSELQDLYDAEKYRQQQNYQRVTTR 62
Query: 281 FKIVKELYSTILTSVILYNKWIYVAWRKSEQIGAMFNISPDREIIISCIFMTFITLFNFI 460
F +S +L V L +EQ+ II + IF + L +
Sbjct: 63 FGFATSTFSLVLVLVFLGVDGFAWLHGMAEQLSG-------NGIIQALIFFGALWLAQDL 115
Query: 461 VNKPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLGGDMF 640
++ PF +Y FV+E+R GFN + F+ D++K L++++ I++ + +F
Sbjct: 116 LSTPFDLYQTFVIEQRFGFNTMDGKTFVTDKLKGWLLTVILGGAILTGIAWFYYQTKALF 175
Query: 641 XXXXXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLRTA 763
I PL +K L +G L+T+
Sbjct: 176 WLYSWITVTGFSLFFTLFYSNLIVPLFNKQTKLEEGELKTS 216
>UniRef50_Q60BD9 Cluster: Peptidase, M48 family; n=4;
Proteobacteria|Rep: Peptidase, M48 family -
Methylococcus capsulatus
Length = 453
Score = 55.6 bits (128), Expect = 1e-06
Identities = 30/100 (30%), Positives = 47/100 (47%)
Frame = +2
Query: 458 IVNKPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLGGDM 637
++ P +Y F +EER GFN+ T R F D LSLVI P++++ ++++ G
Sbjct: 155 LLELPLNLYQTFRIEERFGFNRTTPRQFAIDLALQTGLSLVIGAPLLALILWVMDSAGAQ 214
Query: 638 FXXXXXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLR 757
+ IAPL +KF PL D +L+
Sbjct: 215 WWIVAWAILMAFSILMSWAFPTLIAPLFNKFTPLADATLK 254
>UniRef50_Q18GJ2 Cluster: CAAX prenyl proteinase / zinc
metalloproteinase; n=1; Haloquadratum walsbyi DSM
16790|Rep: CAAX prenyl proteinase / zinc
metalloproteinase - Haloquadratum walsbyi (strain DSM
16790)
Length = 448
Score = 54.4 bits (125), Expect = 3e-06
Identities = 29/101 (28%), Positives = 47/101 (46%)
Frame = +2
Query: 461 VNKPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLGGDMF 640
++ PF +Y FV+E+R GFN QTV +++D I L + L+ I +++I ++
Sbjct: 119 LSAPFDLYKTFVIEDRFGFNNQTVMLWLRDWIIGLMIGLIAATLIGGTVLWVIEAVPSLW 178
Query: 641 XXXXXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLRTA 763
IAPL + F P+ G+LR A
Sbjct: 179 PVLGWLIVIGVSLATMVIYPRVIAPLFNDFEPIESGALRDA 219
>UniRef50_Q7MAI4 Cluster: PUTATIVE ZINC-METALLO PROTEASE; n=1;
Wolinella succinogenes|Rep: PUTATIVE ZINC-METALLO
PROTEASE - Wolinella succinogenes
Length = 415
Score = 51.6 bits (118), Expect = 2e-05
Identities = 54/219 (24%), Positives = 92/219 (42%), Gaps = 2/219 (0%)
Frame = +2
Query: 107 ILYLILLFTWVEY-LWEQYLSLRQLK-IYKTNNTIPEDLKEMLNEDLFKKARLYGIDKAQ 280
+L + L W+ Y L + LS Q++ I + + P +L E +K+A Y K
Sbjct: 13 VLMIFTLAFWLFYTLPKLLLSWLQIRHIERFSRATPI----ILEEKGYKEAAAYAKSKEG 68
Query: 281 FKIVKELYSTILTSVILYNKWIYVAWRKSEQIGAMFNISPDREIIISCIFMTFITLFNFI 460
+V+ L L + LY ++ + +G + + S +F+ + +
Sbjct: 69 LAMVETLLEGALFGIWLYGGLFWL----EQNLG-----ETEPSWLGSLLFVLGFVILGSL 119
Query: 461 VNKPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLGGDMF 640
P Y +L+ R GF K + FI DQ+KSL L L++ PI+ ++I+ D +
Sbjct: 120 FLLPLEAYKKLILDRRFGFAKGDAKLFILDQLKSLALWLLLGSPILLALLWILKNLEDWW 179
Query: 641 XXXXXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLR 757
IAPL ++F PL D SL+
Sbjct: 180 -LYGWGLVMGILLLANLFYPTLIAPLFNRFTPLEDASLQ 217
>UniRef50_A0RNE9 Cluster: Peptidase, M48 family; n=2;
Campylobacter|Rep: Peptidase, M48 family - Campylobacter
fetus subsp. fetus (strain 82-40)
Length = 399
Score = 51.6 bits (118), Expect = 2e-05
Identities = 48/184 (26%), Positives = 84/184 (45%), Gaps = 4/184 (2%)
Frame = +2
Query: 224 MLNEDLFKKARLYGIDKAQFKIVKELYSTILTSVILYNKWIYVAWRKSEQIGAMF---NI 394
+L+E +K+A I +F I +YS IL +I+++ W GA F I
Sbjct: 37 VLSETDYKQAAKVAIINQKFSISNTVYSAIL--LIIWSIW-----------GASFLQNMI 83
Query: 395 SPDREIIISCIFMTFITLFNFIVNKPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLS 574
+P+ I + + + L + I+ PF +Y FV +++ GF+ T + FI D +KS F+
Sbjct: 84 APNGSIFENTLLVVVFLLTSAILQLPFDVYSSFVKDKKLGFSNITWKIFIVDTLKS-FIM 142
Query: 575 LVITLPIISVAIYIIMLG-GDMFXXXXXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGS 751
+VI ++S I + G+ + IAP+ +K PL +
Sbjct: 143 IVIFGGLVSWLILLCFEWLGNSWWIWAFGLSFAIILLINLIYPTIIAPIFNKVTPLANEE 202
Query: 752 LRTA 763
L++A
Sbjct: 203 LKSA 206
>UniRef50_Q0ADS6 Cluster: Ste24 endopeptidase; n=4;
Betaproteobacteria|Rep: Ste24 endopeptidase -
Nitrosomonas eutropha (strain C71)
Length = 422
Score = 50.8 bits (116), Expect = 4e-05
Identities = 28/100 (28%), Positives = 46/100 (46%)
Frame = +2
Query: 458 IVNKPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLGGDM 637
IV PF Y FV+E+++GFNK T F D +K + ++ P++ ++++ GD
Sbjct: 115 IVAIPFNYYRTFVIEQQYGFNKMTRAMFFTDLVKQTVVVALLGAPLLLSVLWLMEKTGDN 174
Query: 638 FXXXXXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLR 757
+ IAPL +KF PL + L+
Sbjct: 175 WWLYTWLTWIGFNLFLLAVYPNWIAPLFNKFSPLENDLLK 214
>UniRef50_Q74GC8 Cluster: Peptidase, M48 family; n=6;
Desulfuromonadales|Rep: Peptidase, M48 family -
Geobacter sulfurreducens
Length = 414
Score = 49.6 bits (113), Expect = 8e-05
Identities = 36/158 (22%), Positives = 73/158 (46%), Gaps = 1/158 (0%)
Frame = +2
Query: 149 WEQYLSLRQLK-IYKTNNTIPEDLKEMLNEDLFKKARLYGIDKAQFKIVKELYSTILTSV 325
+E L + LK + + T+P+ ++E + A Y +D+++ I + L + L
Sbjct: 15 FEHLLRIMNLKHLRRQGTTVPDGFAGAVDEGSLRTATAYTLDRSRLGIAESLVDSGLLVG 74
Query: 326 ILYNKWIYVAWRKSEQIGAMFNISPDREIIISCIFMTFITLFNFIVNKPFTIYGVFVLEE 505
L+ + + R + + F I+ +F ++L + PF +Y FV+E
Sbjct: 75 FLFAGILPLFDRWVASLTSSF-------ILGGVVFFLLLSLVQSALAIPFGLYETFVIER 127
Query: 506 RHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYII 619
R+GF T + + D +KS +S+ + +IS A ++
Sbjct: 128 RYGFTTITPKLWWSDLLKSTCISMTLATLMISGAFALV 165
>UniRef50_Q3ZYX3 Cluster: Peptidase, M48 family; n=3;
Dehalococcoides|Rep: Peptidase, M48 family -
Dehalococcoides sp. (strain CBDB1)
Length = 392
Score = 41.1 bits (92), Expect = 0.029
Identities = 29/114 (25%), Positives = 50/114 (43%), Gaps = 1/114 (0%)
Frame = +2
Query: 425 IFMTFITLFNFIVNKPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISV 604
I+ + I + PF Y +VL +R+G QT + F D KS ++LV+ + +++
Sbjct: 76 IYFLLLACVYEIFSLPFDYYTGYVLGKRYGVLSQTRQTFFADAAKSFLITLVMGVLLVA- 134
Query: 605 AIYIIM-LGGDMFXXXXXXXXXXXXXXXXXXXXXXIAPLXDKFVPLPDGSLRTA 763
A+Y +M D++ + PL PL DG L+T+
Sbjct: 135 AVYAVMGAWPDIWWLLVWLGFLAVSMGLTFIAPIWLIPLFYPMKPLDDGELKTS 188
>UniRef50_Q3A4R8 Cluster: Putative FtsZ-like Zn-dependent protease;
n=1; Pelobacter carbinolicus DSM 2380|Rep: Putative
FtsZ-like Zn-dependent protease - Pelobacter
carbinolicus (strain DSM 2380 / Gra Bd 1)
Length = 425
Score = 39.5 bits (88), Expect = 0.089
Identities = 35/171 (20%), Positives = 78/171 (45%), Gaps = 3/171 (1%)
Frame = +2
Query: 116 LILLFTWVEYLWEQYLSLRQLKI-YKTNNTIPEDLKEMLNEDLFKKARLYGIDKAQFKIV 292
L+ ++ +V ++ EQ L ++ ++ + IP + +A Y K Q ++
Sbjct: 5 LLSVYLFV-FICEQILEWFNIRYQHRHAHHIPAIFARHYDPSTVHRALAYETRKKQAALI 63
Query: 293 KELYSTILTSVILYNKWI--YVAWRKSEQIGAMFNISPDREIIISCIFMTFITLFNFIVN 466
+ S L + ++ W+ Y AW + +I F I +F + + +++
Sbjct: 64 ETGLSAALFAAFMFGGWLPRYDAW--TSEISETF-------IGQGVLFFLGLLIVQMLLD 114
Query: 467 KPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYII 619
PF+ Y F +E GFN +R ++ D K L LS+++ +++ ++++
Sbjct: 115 LPFSWYRNFRIEAHFGFNTMPLRLWLIDAGKGLVLSVLLYGMLLTGVLWLV 165
>UniRef50_Q4UFQ7 Cluster: Metallo-protease, putative; n=4;
Theileria|Rep: Metallo-protease, putative - Theileria
annulata
Length = 458
Score = 38.7 bits (86), Expect = 0.16
Identities = 26/114 (22%), Positives = 48/114 (42%)
Frame = +2
Query: 215 LKEMLNEDLFKKARLYGIDKAQFKIVKELYSTILTSVILYNKWIYVAWRKSEQIGAMFNI 394
LK L ++K Y DK + ++ EL L+ +N + W S G +
Sbjct: 67 LKPYLTSAAYQKTLEYSRDKLRLEMTFELVHLALSVPFCFNNTLLKFWHLS---GELLRH 123
Query: 395 SPDREIIISCIFMTFITLFNFIVNKPFTIYGVFVLEERHGFNKQTVRFFIKDQI 556
++ ++ F+F+ PF Y + LE++HGF ++ F+K +
Sbjct: 124 KCHYSQVL--VYFALRLGFSFLFRLPFRYYTAYRLEKKHGFKTKSRFVFLKQYL 175
>UniRef50_Q8SSD6 Cluster: CAAX PRENYL PROTEASE 1; n=1;
Encephalitozoon cuniculi|Rep: CAAX PRENYL PROTEASE 1 -
Encephalitozoon cuniculi
Length = 410
Score = 38.7 bits (86), Expect = 0.16
Identities = 42/209 (20%), Positives = 80/209 (38%), Gaps = 1/209 (0%)
Frame = +2
Query: 137 VEYLWEQYLSLRQLKIYKTNNTIPEDLKEMLNEDLFKKARLYGIDKAQFKIVKELYSTIL 316
+ YL+ YL +R+L+ + + + ++ + KK + Y DK I EL ++
Sbjct: 12 MSYLFVVYLKVRELR--QLSKPPSKVYLKLTTLEQVKKTKAYNRDKLIMSIF-ELTLLLM 68
Query: 317 TSVILYNKWIYVAWRKSEQIGAMFNISPDREIIISCIFMTFITLFNFIVNKPFTIYGVFV 496
+ L + + +G+ + +F+ + + P + F
Sbjct: 69 RDLYLIKRGVLENVYTKHFMGSWYG---------DALFLVGYAHLQRLFDLPLGVISTFY 119
Query: 497 LEERHGFNKQTVRFFIKDQIKSLFLSLVITLPIISVAIYII-MLGGDMFXXXXXXXXXXX 673
+E +HGFNK T+ F+ D +K + V+ P V+ II F
Sbjct: 120 IEAKHGFNKTTLSTFLMDFLKMSLIITVLFGPFSYVSTNIIKKYYKTSFYIYLWVFMAVF 179
Query: 674 XXXXXXXXXXXIAPLXDKFVPLPDGSLRT 760
I PL +KF + + +L+T
Sbjct: 180 QIGLVIVYPIAIQPLFNKFEEMEESNLKT 208
>UniRef50_Q7NB70 Cluster: Putative uncharacterized protein; n=1;
Mycoplasma gallisepticum|Rep: Putative uncharacterized
protein - Mycoplasma gallisepticum
Length = 289
Score = 35.1 bits (77), Expect = 1.9
Identities = 22/71 (30%), Positives = 39/71 (54%)
Frame = +2
Query: 410 IIISCIFMTFITLFNFIVNKPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITL 589
II F F T F+ +++ F I+ F L +KQT++ +K+ +SL+ITL
Sbjct: 208 IIYLSSFFEFYT-FDILLSFAFAIFSTFFLLIDQNSDKQTIKTELKNTWLHFLISLIITL 266
Query: 590 PIISVAIYIIM 622
+I++ + II+
Sbjct: 267 -VIAIVLAIIV 276
>UniRef50_Q1NYZ7 Cluster: Preprotein translocase SecY subunit; n=1;
Candidatus Sulcia muelleri str. Hc (Homalodisca
coagulata)|Rep: Preprotein translocase SecY subunit -
Candidatus Sulcia muelleri str. Hc (Homalodisca
coagulata)
Length = 433
Score = 35.1 bits (77), Expect = 1.9
Identities = 28/87 (32%), Positives = 45/87 (51%), Gaps = 1/87 (1%)
Frame = +2
Query: 377 GAMFNISPDREIIISCIFMTFITLFNFIVNKPFTIYGVFVLEERHGFNKQTVRFFIKDQI 556
G +NI III F TF+++ ++ I GV++ + G K T FF+K +
Sbjct: 312 GIWYNILYSILIIIITFFYTFLSIPVNKISDDLKINGVYIPNRKPG--KDTC-FFLKKIV 368
Query: 557 KSLFLSLVITLPIISVAIYI-IMLGGD 634
++L+ + L II++ I I LGGD
Sbjct: 369 SQIYLTGSLLLVIIALLPSIFISLGGD 395
>UniRef50_A2ETL9 Cluster: Putative uncharacterized protein; n=1;
Trichomonas vaginalis G3|Rep: Putative uncharacterized
protein - Trichomonas vaginalis G3
Length = 436
Score = 34.7 bits (76), Expect = 2.5
Identities = 11/47 (23%), Positives = 30/47 (63%)
Frame = +2
Query: 458 IVNKPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPII 598
I + PF+++ +F ++ +HGFNK+ + F+ + + + L++ + ++
Sbjct: 99 ITSFPFSLWQIFYIDSQHGFNKKPLTLFLCEDLLLQLIILIVGIFLV 145
>UniRef50_UPI00004991B2 Cluster: hypothetical protein 173.t00010;
n=1; Entamoeba histolytica HM-1:IMSS|Rep: hypothetical
protein 173.t00010 - Entamoeba histolytica HM-1:IMSS
Length = 471
Score = 34.3 bits (75), Expect = 3.3
Identities = 23/90 (25%), Positives = 47/90 (52%), Gaps = 5/90 (5%)
Frame = +2
Query: 188 KTNNTIPEDLKEM----LNEDLFK-KARLYGIDKAQFKIVKELYSTILTSVILYNKWIYV 352
KT PE+ +E NE + ++ G D+ + KI+KE++ +L ++L NK +
Sbjct: 80 KTKEAPPEETEEFQLKKFNEMIDSTNVQIEGNDEERIKIIKEMFPELLQRILLANK---I 136
Query: 353 AWRKSEQIGAMFNISPDREIIISCIFMTFI 442
++ KS++ G + + RE + S + + +
Sbjct: 137 SFEKSKEGGVLGKFTSLREKVESGLILNVL 166
>UniRef50_Q2RJ44 Cluster: Ste24 endopeptidase precursor; n=1;
Moorella thermoacetica ATCC 39073|Rep: Ste24
endopeptidase precursor - Moorella thermoacetica (strain
ATCC 39073)
Length = 413
Score = 34.3 bits (75), Expect = 3.3
Identities = 24/140 (17%), Positives = 52/140 (37%)
Frame = +2
Query: 341 WIYVAWRKSEQIGAMFNISPDREIIISCIFMTFITLFNFIVNKPFTIYGVFVLEERHGFN 520
W+ + R + ++ R ++ I L + PF YG F+++ + G
Sbjct: 73 WLVYSTRSGAWSERVLRLTGGRYYPALLVYFCLIWLLLKAIGLPFNFYGSFIVQHQWGLA 132
Query: 521 KQTVRFFIKDQIKSLFLSLVITLPIISVAIYIIMLGGDMFXXXXXXXXXXXXXXXXXXXX 700
Q++ + D +K L LV++ + + + +
Sbjct: 133 TQSLASWWSDYLKGSLLDLVLSGAGVLLLFWATGRWPCTWWVAAGLFLSAWLFISTFIWP 192
Query: 701 XXIAPLXDKFVPLPDGSLRT 760
IAP+ ++F P+ G ++T
Sbjct: 193 LIIAPIFNRFQPVTAGPIKT 212
>UniRef50_Q4CYI1 Cluster: Putative uncharacterized protein; n=5;
Trypanosomatidae|Rep: Putative uncharacterized protein -
Trypanosoma cruzi
Length = 759
Score = 34.3 bits (75), Expect = 3.3
Identities = 30/117 (25%), Positives = 54/117 (46%), Gaps = 5/117 (4%)
Frame = +2
Query: 188 KTNNTIPEDLKEMLNEDLFKKA-RLYGIDKAQF---KIVKELYSTILTSVILYNKWIYVA 355
K + + ++ +N+DL + R YG K Q I +E ++ +V L + + VA
Sbjct: 78 KDSRRLDASYQQTVNDDLSGRVLRFYGYTKEQVPESSIERERLRKVVFNVFLEDNTMSVA 137
Query: 356 WRKSEQIGAMFNISPDREIIISCIFMTFITLFNFIVNKPFTIYG-VFVLEERHGFNK 523
+ + G F ++ R I+ T IT +F V +P T YG ++L + F +
Sbjct: 138 EQSPDNSGFAFPLALKRHIV-PMHDGTPITFADFRVGEPITFYGRTYMLYDADKFTR 193
>UniRef50_Q2U6T7 Cluster: Ferric reductase; n=6;
Eurotiomycetidae|Rep: Ferric reductase - Aspergillus
oryzae
Length = 752
Score = 34.3 bits (75), Expect = 3.3
Identities = 24/89 (26%), Positives = 42/89 (47%), Gaps = 2/89 (2%)
Frame = +2
Query: 149 WEQYLSL-RQLKIYKTNNTIPEDLKEMLNEDLFKKARLYGIDKAQFKIVKELYSTILTSV 325
W SL +++ I +T P ++ EM +D + +A YG+ F ++ STI+
Sbjct: 5 WHSIASLVKRIDIPIVASTTPAEIAEM-QQDAWPEAGKYGLGWVYFSVILLAISTIIRFY 63
Query: 326 ILYNKWIYVAWRKSEQIG-AMFNISPDRE 409
L+ I +A K + G + + SP E
Sbjct: 64 HLWGDQIRIALHKEDMAGTSPYVTSPQEE 92
>UniRef50_UPI00006D0DB9 Cluster: Sodium/calcium exchanger protein;
n=1; Tetrahymena thermophila SB210|Rep: Sodium/calcium
exchanger protein - Tetrahymena thermophila SB210
Length = 5392
Score = 33.9 bits (74), Expect = 4.4
Identities = 16/65 (24%), Positives = 34/65 (52%), Gaps = 3/65 (4%)
Frame = +2
Query: 437 FITLFNFIVNKPFTIYGVFVLEERHGFNK--QTVRFFIKD-QIKSLFLSLVITLPIISVA 607
F LFN+++ P + + + +N +F+ + +K LF+++ TLP+ +
Sbjct: 229 FFCLFNYLLFVPILVQRLILQSSSSCYNNLDNDAKFYFTNFNMKQLFITVTDTLPLFPIV 288
Query: 608 IYIIM 622
+YII+
Sbjct: 289 VYIII 293
>UniRef50_Q8IK91 Cluster: Putative uncharacterized protein; n=1;
Plasmodium falciparum 3D7|Rep: Putative uncharacterized
protein - Plasmodium falciparum (isolate 3D7)
Length = 694
Score = 33.9 bits (74), Expect = 4.4
Identities = 23/95 (24%), Positives = 46/95 (48%), Gaps = 8/95 (8%)
Frame = +2
Query: 329 LYNKWIYVAWRKSEQIGAMFNISPDREIIISCIFMTFITLFNFIVNKPFTIYGVF----- 493
+ N+ ++ + K++ I + I D E I CIF+ +I + K IY ++
Sbjct: 189 ILNEIFFLIYLKNKNIILIEKIFWDNEKKIICIFLQYIKYQSMYFKKKIGIYSIYKKNKK 248
Query: 494 ---VLEERHGFNKQTVRFFIKDQIKSLFLSLVITL 589
+LE+ + N ++ + ++ +K LFL + TL
Sbjct: 249 KCKILEKNNKNNSVQIQLYSQNFLKYLFLQIYKTL 283
>UniRef50_Q5ZVH0 Cluster: Serine-type D-Ala-D-Ala carboxypeptidase;
n=3; Legionella pneumophila|Rep: Serine-type D-Ala-D-Ala
carboxypeptidase - Legionella pneumophila subsp.
pneumophila (strain Philadelphia 1 /ATCC 33152 / DSM
7513)
Length = 553
Score = 33.5 bits (73), Expect = 5.8
Identities = 18/64 (28%), Positives = 37/64 (57%), Gaps = 1/64 (1%)
Frame = +2
Query: 80 IIMNFDEXAILYLILLFTWVEYLWE-QYLSLRQLKIYKTNNTIPEDLKEMLNEDLFKKAR 256
++ + + + Y+ LL + ++ Q LS KI N +P+DL +++N+ ++KKA
Sbjct: 5 MMKRYSKRLLTYIYLLMKSIPLVFTMQQLSYSTDKIPIPTNKLPDDLNKVMNKSIYKKA- 63
Query: 257 LYGI 268
L+G+
Sbjct: 64 LWGL 67
>UniRef50_A5K0C4 Cluster: Putative uncharacterized protein; n=1;
Plasmodium vivax|Rep: Putative uncharacterized protein -
Plasmodium vivax
Length = 2371
Score = 33.5 bits (73), Expect = 5.8
Identities = 34/147 (23%), Positives = 58/147 (39%)
Frame = +2
Query: 80 IIMNFDEXAILYLILLFTWVEYLWEQYLSLRQLKIYKTNNTIPEDLKEMLNEDLFKKARL 259
+I + LY L+ +++ L+ + + L IYK K++ L K
Sbjct: 835 LIKKLYDILFLYKKELYLYID-LFNNMCANKDLDIYKKFLFCLNIYKKIKKPILIFKNNS 893
Query: 260 YGIDKAQFKIVKELYSTILTSVILYNKWIYVAWRKSEQIGAMFNISPDREIIISCIFMTF 439
Y ++KI+ +LY T + Y YV W K+ + M I I+ + F
Sbjct: 894 YITTSNEYKIIVKLYVTFCKKMFSYIIETYVIW-KNNSLSQMNKFLSSNLITIN-KQLNF 951
Query: 440 ITLFNFIVNKPFTIYGVFVLEERHGFN 520
+ NF T+Y +E + FN
Sbjct: 952 FYVINFDSTFFKTLYEYAYIESMYDFN 978
>UniRef50_A0EGC9 Cluster: Chromosome undetermined scaffold_95, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_95,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 356
Score = 33.5 bits (73), Expect = 5.8
Identities = 22/99 (22%), Positives = 49/99 (49%), Gaps = 8/99 (8%)
Frame = +2
Query: 155 QYLSLRQLKIYKTNNTIPEDLKEMLNEDLFKKARLY---GI-DKAQFKIVKEL----YST 310
++ L++L I++ N + ++ F+K L G+ D+ F+I+K Y
Sbjct: 208 EFYKLKKLSIFRAQNIEENSMLQLFQGKQFQKINLNQCDGVTDRVLFQIIKNCQQLKYIN 267
Query: 311 ILTSVILYNKWIYVAWRKSEQIGAMFNISPDREIIISCI 427
+ S+ +YN W+ V + ++ Q+ ++ I +++ CI
Sbjct: 268 LSWSIDIYNHWVSVLFEEALQLEEVYLIG-CKQLTDECI 305
>UniRef50_Q97MN0 Cluster: Predicted ABC transporter, permease
component; n=1; Clostridium acetobutylicum|Rep:
Predicted ABC transporter, permease component -
Clostridium acetobutylicum
Length = 451
Score = 33.1 bits (72), Expect = 7.7
Identities = 17/70 (24%), Positives = 38/70 (54%)
Frame = +2
Query: 416 ISCIFMTFITLFNFIVNKPFTIYGVFVLEERHGFNKQTVRFFIKDQIKSLFLSLVITLPI 595
++ I + I++F I+ + T +F G+ + +R +K + + ++ ++ITLP+
Sbjct: 337 VTVIVLIDISIFYKIIMEADTKNHIFNQLALIGYTTEQIREIVKQEFR-IYYGIIITLPL 395
Query: 596 ISVAIYIIML 625
V I+ I+L
Sbjct: 396 FHVIIFFILL 405
>UniRef50_Q04R76 Cluster: Cation/multidrug efflux pump; n=2;
Leptospira borgpetersenii serovar Hardjo-bovis|Rep:
Cation/multidrug efflux pump - Leptospira borgpetersenii
serovar Hardjo-bovis (strain JB197)
Length = 1065
Score = 33.1 bits (72), Expect = 7.7
Identities = 22/71 (30%), Positives = 41/71 (57%), Gaps = 2/71 (2%)
Frame = +2
Query: 263 GIDKAQFKIVKELYSTILTSVILYNKWIYVAWRKSEQIGAMFNISPDREIIISCIF-MTF 439
GI KA ++ KEL++++LTS+ ++ I+ + R+ + I+ ++ S I +TF
Sbjct: 421 GIVKASSRLSKELFASVLTSIAVFFP-IFFSSRELRDLYGGLAITVSASLVTSLIVSLTF 479
Query: 440 I-TLFNFIVNK 469
+ TL FI+ K
Sbjct: 480 LPTLAKFILTK 490
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 677,737,813
Number of Sequences: 1657284
Number of extensions: 12700086
Number of successful extensions: 37022
Number of sequences better than 10.0: 84
Number of HSP's better than 10.0 without gapping: 35067
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 36953
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 63381147830
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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