Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P03_F_O19
(750 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Z46376-1|CAA86511.1| 917|Homo sapiens Human hexokinase II cDNA ... 214 3e-55
Z46354-1|CAA86476.2| 916|Homo sapiens hexokinase II protein. 214 3e-55
BC064369-1|AAH64369.1| 917|Homo sapiens hexokinase 2 protein. 214 3e-55
BC021116-1|AAH21116.1| 917|Homo sapiens hexokinase 2 protein. 214 3e-55
AY623118-1|AAT38114.1| 917|Homo sapiens hexokinase 2 protein. 214 3e-55
AF148513-1|AAD30174.1| 917|Homo sapiens hexokinase II protein. 214 3e-55
AC019069-1|AAX93084.1| 344|Homo sapiens unknown protein. 214 3e-55
BC110505-1|AAI10506.2| 917|Homo sapiens hexokinase domain conta... 201 2e-51
BC110504-1|AAI10505.1| 917|Homo sapiens hexokinase domain conta... 201 2e-51
BC012337-1|AAH12337.1| 677|Homo sapiens HKDC1 protein protein. 201 2e-51
AL596223-3|CAH71500.1| 917|Homo sapiens hexokinase domain conta... 201 2e-51
AK026414-1|BAB15478.1| 325|Homo sapiens protein ( Homo sapiens ... 201 2e-51
AC104135-1|AAY24209.1| 573|Homo sapiens unknown protein. 196 5e-50
M90299-1|AAA52562.1| 465|Homo sapiens glucokinase protein. 195 1e-49
M88011-1|AAA51824.1| 465|Homo sapiens glucokinase protein. 195 1e-49
EU008605-1|ABS31137.1| 465|Homo sapiens glucokinase protein. 195 1e-49
BT007062-1|AAP35711.1| 465|Homo sapiens glucokinase (hexokinase... 195 1e-49
BC001890-1|AAH01890.1| 465|Homo sapiens glucokinase (hexokinase... 195 1e-49
AF041022-1|AAB97680.1| 465|Homo sapiens glucokinase protein. 195 1e-49
AF041022-3|AAB97682.1| 464|Homo sapiens glucokinase protein. 194 2e-49
AF041022-2|AAB97681.1| 466|Homo sapiens glucokinase protein. 194 2e-49
M69051-1|AAB59563.1| 464|Homo sapiens glucokinase protein. 194 4e-49
BC021278-1|AAH21278.1| 427|Homo sapiens HKDC1 protein protein. 193 5e-49
X66957-1|CAA47379.1| 631|Homo sapiens hexokinase type 1 protein. 189 8e-48
M75126-1|AAA52646.1| 917|Homo sapiens hexokinase 1 protein. 189 8e-48
BC008730-1|AAH08730.1| 917|Homo sapiens hexokinase 1 protein. 189 8e-48
AL596223-9|CAH71506.1| 917|Homo sapiens hexokinase 1 protein. 189 8e-48
AF016365-4|AAC15862.1| 917|Homo sapiens hexokinase I protein. 189 8e-48
AF016365-3|AAC15863.1| 916|Homo sapiens hexokinase IR protein. 189 8e-48
AF016365-2|AAF82320.1| 905|Homo sapiens hexokinase 1 isoform td... 189 8e-48
AF016365-1|AAF82319.1| 921|Homo sapiens hexokinase 1 isoform ta... 189 8e-48
AB209526-1|BAD92763.1| 949|Homo sapiens hexokinase 1 isoform HK... 189 8e-48
AL596223-8|CAH71505.1| 291|Homo sapiens hexokinase 1 protein. 186 7e-47
U51333-1|AAC50732.1| 923|Homo sapiens hexokinase III protein. 178 2e-44
BC028129-1|AAH28129.1| 923|Homo sapiens hexokinase 3 (white cel... 178 2e-44
AB208951-1|BAD92188.1| 960|Homo sapiens Hexokinase 3 variant pr... 178 2e-44
U42303-1|AAC50422.1| 566|Homo sapiens ATP:D-hexose 6-phosphotra... 167 3e-41
AL596223-5|CAH71502.1| 139|Homo sapiens hexokinase 1 protein. 98 3e-20
AL596223-7|CAH71504.1| 114|Homo sapiens hexokinase 1 protein. 80 7e-15
AF073786-1|AAC25424.1| 114|Homo sapiens testis-specific hexokin... 80 7e-15
DQ871602-1|ABI49509.1| 127|Homo sapiens HK2 protein. 79 2e-14
D25412-1|BAA04999.1| 126|Homo sapiens type 2 hexokinase protein. 72 2e-12
BX538078-1|CAD98002.1| 160|Homo sapiens hypothetical protein pr... 38 0.039
BC121179-1|AAI21180.1| 722|Homo sapiens glucosamine (UDP-N-acet... 30 7.7
AY531128-1|AAS59259.1| 722|Homo sapiens UDP-N-acetylglucosamine... 30 7.7
AY531127-1|AAS59258.1| 722|Homo sapiens UDP-N-acetylglucosamine... 30 7.7
AY531126-1|AAS59257.1| 722|Homo sapiens UDP-N-acetylglucosamine... 30 7.7
AM697709-1|CAM91425.1| 681|Homo sapiens UDP-N-acetylglucosamine... 30 7.7
AM697708-1|CAM91424.1| 753|Homo sapiens UDP-N-acetylglucosamine... 30 7.7
AL158830-7|CAD13389.1| 722|Homo sapiens glucosamine (UDP-N-acet... 30 7.7
AJ238764-1|CAB42607.1| 722|Homo sapiens UDP-N-acetylglucosamine... 30 7.7
AF317635-1|AAG31661.1| 722|Homo sapiens UDP-N-acetylglucosamine... 30 7.7
AF155663-1|AAD38197.1| 722|Homo sapiens UDP-N-acetylglucosamine... 30 7.7
AF051852-1|AAD32251.1| 722|Homo sapiens UDP-N-acetylglucosamine... 30 7.7
>Z46376-1|CAA86511.1| 917|Homo sapiens Human hexokinase II cDNA
protein.
Length = 917
Score = 214 bits (522), Expect = 3e-55
Identities = 101/210 (48%), Positives = 142/210 (67%), Gaps = 3/210 (1%)
Frame = +1
Query: 130 DNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKE 309
D +Q++ + ++++D+ + EI R +++KGL H A VK T+++ P+G E
Sbjct: 17 DQVQKVDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDGTE 76
Query: 310 RGKFLALDLGGTNFRVLIINLGENHF---DMQSKIYAIPKHIMTGTGIALFDHIAECLAN 480
G+FLALDLGGTNFRVL + + +N +M+++IYAIP+ IM G+G LFDHIAECLAN
Sbjct: 77 HGEFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMRGSGTQLFDHIAECLAN 136
Query: 481 FMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARR 660
FM + + +++L LGFTFSFP Q L + L WTKGF SGV G DVV ++ AI RR
Sbjct: 137 FMDKLQIKDKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEGRDVVALIRKAIQRR 196
Query: 661 GDVQIDICAILNDTTGTLMSCAWKNHNCXI 750
GD IDI A++NDT GT+M+C + +HNC I
Sbjct: 197 GDFDIDIVAVVNDTVGTMMTCGYDDHNCEI 226
Score = 196 bits (479), Expect = 5e-50
Identities = 93/212 (43%), Positives = 142/212 (66%), Gaps = 3/212 (1%)
Frame = +1
Query: 124 VVDNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNG 303
+ D + ++ E L+++ Q+ E+ R+ ++++GLS+ H A VK TY+ P+G
Sbjct: 463 LADQHRARQKTLEHLQLSHDQLLEVKRRMKVEMERGLSKETHASAPVKMLPTYVCATPDG 522
Query: 304 KERGKFLALDLGGTNFRVLIINLGENHF---DMQSKIYAIPKHIMTGTGIALFDHIAECL 474
E+G FLALDLGGTNFRVL++ + + +M +KIYAIP+ +M GTG LFDHI +C+
Sbjct: 523 TEKGDFLALDLGGTNFRVLLVRVRNGKWGGVEMHNKIYAIPQEVMHGTGDELFDHIVQCI 582
Query: 475 ANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIA 654
A+F++ G+ L LGFTFSFP +Q L + +L +WTKGF SG GEDVV LK+AI
Sbjct: 583 ADFLEYMGMKGVSLPLGFTFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIH 642
Query: 655 RRGDVQIDICAILNDTTGTLMSCAWKNHNCXI 750
RR + +D+ A++NDT GT+M+C +++ +C +
Sbjct: 643 RREEFDLDVVAVVNDTVGTMMTCGFEDPHCEV 674
>Z46354-1|CAA86476.2| 916|Homo sapiens hexokinase II protein.
Length = 916
Score = 214 bits (522), Expect = 3e-55
Identities = 101/210 (48%), Positives = 142/210 (67%), Gaps = 3/210 (1%)
Frame = +1
Query: 130 DNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKE 309
D +Q++ + ++++D+ + EI R +++KGL H A VK T+++ P+G E
Sbjct: 17 DQVQKVDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDGTE 76
Query: 310 RGKFLALDLGGTNFRVLIINLGENHF---DMQSKIYAIPKHIMTGTGIALFDHIAECLAN 480
G+FLALDLGGTNFRVL + + +N +M+++IYAIP+ IM G+G LFDHIAECLAN
Sbjct: 77 HGEFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMRGSGTQLFDHIAECLAN 136
Query: 481 FMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARR 660
FM + + +++L LGFTFSFP Q L + L WTKGF SGV G DVV ++ AI RR
Sbjct: 137 FMDKLHIKDKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEGRDVVALIRKAIQRR 196
Query: 661 GDVQIDICAILNDTTGTLMSCAWKNHNCXI 750
GD IDI A++NDT GT+M+C + +HNC I
Sbjct: 197 GDFDIDIVAVVNDTVGTMMTCGYDDHNCEI 226
Score = 196 bits (479), Expect = 5e-50
Identities = 93/212 (43%), Positives = 142/212 (66%), Gaps = 3/212 (1%)
Frame = +1
Query: 124 VVDNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNG 303
+ D + ++ E L+++ Q+ E+ R+ ++++GLS+ H A VK TY+ P+G
Sbjct: 463 LADQHRARQKTLEHLQLSHDQLLEVKRRMKVEMERGLSKETHASAPVKMLPTYVCATPDG 522
Query: 304 KERGKFLALDLGGTNFRVLIINLGENHF---DMQSKIYAIPKHIMTGTGIALFDHIAECL 474
E+G FLALDLGGTNFRVL++ + + +M +KIYAIP+ +M GTG LFDHI +C+
Sbjct: 523 TEKGDFLALDLGGTNFRVLLVRVRNGKWGGVEMHNKIYAIPQEVMHGTGDELFDHIVQCI 582
Query: 475 ANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIA 654
A+F++ G+ L LGFTFSFP +Q L + +L +WTKGF SG GEDVV LK+AI
Sbjct: 583 ADFLEYMGMKGVSLPLGFTFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIH 642
Query: 655 RRGDVQIDICAILNDTTGTLMSCAWKNHNCXI 750
RR + +D+ A++NDT GT+M+C +++ +C +
Sbjct: 643 RREEFDLDVVAVVNDTVGTMMTCGFEDPHCEV 674
>BC064369-1|AAH64369.1| 917|Homo sapiens hexokinase 2 protein.
Length = 917
Score = 214 bits (522), Expect = 3e-55
Identities = 101/210 (48%), Positives = 142/210 (67%), Gaps = 3/210 (1%)
Frame = +1
Query: 130 DNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKE 309
D +Q++ + ++++D+ + EI R +++KGL H A VK T+++ P+G E
Sbjct: 17 DQVQKVDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDGTE 76
Query: 310 RGKFLALDLGGTNFRVLIINLGENHF---DMQSKIYAIPKHIMTGTGIALFDHIAECLAN 480
G+FLALDLGGTNFRVL + + +N +M+++IYAIP+ IM G+G LFDHIAECLAN
Sbjct: 77 HGEFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMRGSGTQLFDHIAECLAN 136
Query: 481 FMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARR 660
FM + + +++L LGFTFSFP Q L + L WTKGF SGV G DVV ++ AI RR
Sbjct: 137 FMDKLQIKDKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEGRDVVALIRKAIQRR 196
Query: 661 GDVQIDICAILNDTTGTLMSCAWKNHNCXI 750
GD IDI A++NDT GT+M+C + +HNC I
Sbjct: 197 GDFDIDIVAVVNDTVGTMMTCGYDDHNCEI 226
Score = 196 bits (479), Expect = 5e-50
Identities = 93/212 (43%), Positives = 142/212 (66%), Gaps = 3/212 (1%)
Frame = +1
Query: 124 VVDNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNG 303
+ D + ++ E L+++ Q+ E+ R+ ++++GLS+ H A VK TY+ P+G
Sbjct: 463 LADQHRARQKTLEHLQLSHDQLLEVKRRMKVEMERGLSKETHASAPVKMLPTYVCATPDG 522
Query: 304 KERGKFLALDLGGTNFRVLIINLGENHF---DMQSKIYAIPKHIMTGTGIALFDHIAECL 474
E+G FLALDLGGTNFRVL++ + + +M +KIYAIP+ +M GTG LFDHI +C+
Sbjct: 523 TEKGDFLALDLGGTNFRVLLVRVRNGKWGGVEMHNKIYAIPQEVMHGTGDELFDHIVQCI 582
Query: 475 ANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIA 654
A+F++ G+ L LGFTFSFP +Q L + +L +WTKGF SG GEDVV LK+AI
Sbjct: 583 ADFLEYMGMKGVSLPLGFTFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIH 642
Query: 655 RRGDVQIDICAILNDTTGTLMSCAWKNHNCXI 750
RR + +D+ A++NDT GT+M+C +++ +C +
Sbjct: 643 RREEFDLDVVAVVNDTVGTMMTCGFEDPHCEV 674
>BC021116-1|AAH21116.1| 917|Homo sapiens hexokinase 2 protein.
Length = 917
Score = 214 bits (522), Expect = 3e-55
Identities = 101/210 (48%), Positives = 142/210 (67%), Gaps = 3/210 (1%)
Frame = +1
Query: 130 DNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKE 309
D +Q++ + ++++D+ + EI R +++KGL H A VK T+++ P+G E
Sbjct: 17 DQVQKVDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDGTE 76
Query: 310 RGKFLALDLGGTNFRVLIINLGENHF---DMQSKIYAIPKHIMTGTGIALFDHIAECLAN 480
G+FLALDLGGTNFRVL + + +N +M+++IYAIP+ IM G+G LFDHIAECLAN
Sbjct: 77 HGEFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMRGSGTQLFDHIAECLAN 136
Query: 481 FMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARR 660
FM + + +++L LGFTFSFP Q L + L WTKGF SGV G DVV ++ AI RR
Sbjct: 137 FMDKLQIKDKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEGRDVVALIRKAIQRR 196
Query: 661 GDVQIDICAILNDTTGTLMSCAWKNHNCXI 750
GD IDI A++NDT GT+M+C + +HNC I
Sbjct: 197 GDFDIDIVAVVNDTVGTMMTCGYDDHNCEI 226
Score = 196 bits (479), Expect = 5e-50
Identities = 93/212 (43%), Positives = 142/212 (66%), Gaps = 3/212 (1%)
Frame = +1
Query: 124 VVDNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNG 303
+ D + ++ E L+++ Q+ E+ R+ ++++GLS+ H A VK TY+ P+G
Sbjct: 463 LADQHRARQKTLEHLQLSHDQLLEVKRRMKVEMERGLSKETHASAPVKMLPTYVCATPDG 522
Query: 304 KERGKFLALDLGGTNFRVLIINLGENHF---DMQSKIYAIPKHIMTGTGIALFDHIAECL 474
E+G FLALDLGGTNFRVL++ + + +M +KIYAIP+ +M GTG LFDHI +C+
Sbjct: 523 TEKGDFLALDLGGTNFRVLLVRVRNGKWGGVEMHNKIYAIPQEVMHGTGDELFDHIVQCI 582
Query: 475 ANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIA 654
A+F++ G+ L LGFTFSFP +Q L + +L +WTKGF SG GEDVV LK+AI
Sbjct: 583 ADFLEYMGMKGVSLPLGFTFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIH 642
Query: 655 RRGDVQIDICAILNDTTGTLMSCAWKNHNCXI 750
RR + +D+ A++NDT GT+M+C +++ +C +
Sbjct: 643 RREEFDLDVVAVVNDTVGTMMTCGFEDPHCEV 674
>AY623118-1|AAT38114.1| 917|Homo sapiens hexokinase 2 protein.
Length = 917
Score = 214 bits (522), Expect = 3e-55
Identities = 101/210 (48%), Positives = 142/210 (67%), Gaps = 3/210 (1%)
Frame = +1
Query: 130 DNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKE 309
D +Q++ + ++++D+ + EI R +++KGL H A VK T+++ P+G E
Sbjct: 17 DQVQKVDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDGTE 76
Query: 310 RGKFLALDLGGTNFRVLIINLGENHF---DMQSKIYAIPKHIMTGTGIALFDHIAECLAN 480
G+FLALDLGGTNFRVL + + +N +M+++IYAIP+ IM G+G LFDHIAECLAN
Sbjct: 77 HGEFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMRGSGTQLFDHIAECLAN 136
Query: 481 FMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARR 660
FM + + +++L LGFTFSFP Q L + L WTKGF SGV G DVV ++ AI RR
Sbjct: 137 FMDKLQIKDKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEGRDVVALIRKAIQRR 196
Query: 661 GDVQIDICAILNDTTGTLMSCAWKNHNCXI 750
GD IDI A++NDT GT+M+C + +HNC I
Sbjct: 197 GDFDIDIVAVVNDTVGTMMTCGYDDHNCEI 226
Score = 196 bits (479), Expect = 5e-50
Identities = 93/212 (43%), Positives = 142/212 (66%), Gaps = 3/212 (1%)
Frame = +1
Query: 124 VVDNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNG 303
+ D + ++ E L+++ Q+ E+ R+ ++++GLS+ H A VK TY+ P+G
Sbjct: 463 LADQHRARQKTLEHLQLSHDQLLEVKRRMKVEMERGLSKETHASAPVKMLPTYVCATPDG 522
Query: 304 KERGKFLALDLGGTNFRVLIINLGENHF---DMQSKIYAIPKHIMTGTGIALFDHIAECL 474
E+G FLALDLGGTNFRVL++ + + +M +KIYAIP+ +M GTG LFDHI +C+
Sbjct: 523 TEKGDFLALDLGGTNFRVLLVRVRNGKWGGVEMHNKIYAIPQEVMHGTGDELFDHIVQCI 582
Query: 475 ANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIA 654
A+F++ G+ L LGFTFSFP +Q L + +L +WTKGF SG GEDVV LK+AI
Sbjct: 583 ADFLEYMGMKGVSLPLGFTFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIH 642
Query: 655 RRGDVQIDICAILNDTTGTLMSCAWKNHNCXI 750
RR + +D+ A++NDT GT+M+C +++ +C +
Sbjct: 643 RREEFDLDVVAVVNDTVGTMMTCGFEDPHCEV 674
>AF148513-1|AAD30174.1| 917|Homo sapiens hexokinase II protein.
Length = 917
Score = 214 bits (522), Expect = 3e-55
Identities = 101/210 (48%), Positives = 142/210 (67%), Gaps = 3/210 (1%)
Frame = +1
Query: 130 DNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKE 309
D +Q++ + ++++D+ + EI R +++KGL H A VK T+++ P+G E
Sbjct: 17 DQVQKVDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDGTE 76
Query: 310 RGKFLALDLGGTNFRVLIINLGENHF---DMQSKIYAIPKHIMTGTGIALFDHIAECLAN 480
G+FLALDLGGTNFRVL + + +N +M+++IYAIP+ IM G+G LFDHIAECLAN
Sbjct: 77 HGEFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMRGSGTQLFDHIAECLAN 136
Query: 481 FMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARR 660
FM + + +++L LGFTFSFP Q L + L WTKGF SGV G DVV ++ AI RR
Sbjct: 137 FMDKLQIKDKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEGRDVVALIRKAIQRR 196
Query: 661 GDVQIDICAILNDTTGTLMSCAWKNHNCXI 750
GD IDI A++NDT GT+M+C + +HNC I
Sbjct: 197 GDFDIDIVAVVNDTVGTMMTCGYDDHNCEI 226
Score = 196 bits (479), Expect = 5e-50
Identities = 93/212 (43%), Positives = 142/212 (66%), Gaps = 3/212 (1%)
Frame = +1
Query: 124 VVDNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNG 303
+ D + ++ E L+++ Q+ E+ R+ ++++GLS+ H A VK TY+ P+G
Sbjct: 463 LADQHRARQKTLEHLQLSHDQLLEVKRRMKVEMERGLSKETHASAPVKMLPTYVCATPDG 522
Query: 304 KERGKFLALDLGGTNFRVLIINLGENHF---DMQSKIYAIPKHIMTGTGIALFDHIAECL 474
E+G FLALDLGGTNFRVL++ + + +M +KIYAIP+ +M GTG LFDHI +C+
Sbjct: 523 TEKGDFLALDLGGTNFRVLLVRVRNGKWGGVEMHNKIYAIPQEVMHGTGDELFDHIVQCI 582
Query: 475 ANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIA 654
A+F++ G+ L LGFTFSFP +Q L + +L +WTKGF SG GEDVV LK+AI
Sbjct: 583 ADFLEYMGMKGVSLPLGFTFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIH 642
Query: 655 RRGDVQIDICAILNDTTGTLMSCAWKNHNCXI 750
RR + +D+ A++NDT GT+M+C +++ +C +
Sbjct: 643 RREEFDLDVVAVVNDTVGTMMTCGFEDPHCEV 674
>AC019069-1|AAX93084.1| 344|Homo sapiens unknown protein.
Length = 344
Score = 214 bits (522), Expect = 3e-55
Identities = 101/210 (48%), Positives = 142/210 (67%), Gaps = 3/210 (1%)
Frame = +1
Query: 130 DNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKE 309
D +Q++ + ++++D+ + EI R +++KGL H A VK T+++ P+G E
Sbjct: 17 DQVQKVDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDGTE 76
Query: 310 RGKFLALDLGGTNFRVLIINLGENHF---DMQSKIYAIPKHIMTGTGIALFDHIAECLAN 480
G+FLALDLGGTNFRVL + + +N +M+++IYAIP+ IM G+G LFDHIAECLAN
Sbjct: 77 HGEFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMRGSGTQLFDHIAECLAN 136
Query: 481 FMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARR 660
FM + + +++L LGFTFSFP Q L + L WTKGF SGV G DVV ++ AI RR
Sbjct: 137 FMDKLQIKDKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEGRDVVALIRKAIQRR 196
Query: 661 GDVQIDICAILNDTTGTLMSCAWKNHNCXI 750
GD IDI A++NDT GT+M+C + +HNC I
Sbjct: 197 GDFDIDIVAVVNDTVGTMMTCGYDDHNCEI 226
>BC110505-1|AAI10506.2| 917|Homo sapiens hexokinase domain containing
1 protein.
Length = 917
Score = 201 bits (491), Expect = 2e-51
Identities = 93/198 (46%), Positives = 134/198 (67%), Gaps = 2/198 (1%)
Frame = +1
Query: 163 VLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKERGKFLALDLGG 342
+ ++T +Q+ ++ ++ +L+ GL + H ATV+ TY+ LP+G E+GKFLALDLGG
Sbjct: 476 LFQLTREQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGG 535
Query: 343 TNFRVLIINL--GENHFDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERL 516
TNFRVL++ + G M +KI+AIP IM GTG LFDHI +C+A+F+ G+ L
Sbjct: 536 TNFRVLLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASL 595
Query: 517 ALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARRGDVQIDICAILN 696
LGFTFSFP +Q+ + KG L WTKGF + GEDVV L++AI RR + +DI A++N
Sbjct: 596 PLGFTFSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVN 655
Query: 697 DTTGTLMSCAWKNHNCXI 750
DT GT+M+C +++ NC I
Sbjct: 656 DTVGTMMTCGYEDPNCEI 673
Score = 178 bits (434), Expect = 2e-44
Identities = 83/210 (39%), Positives = 133/210 (63%), Gaps = 3/210 (1%)
Frame = +1
Query: 130 DNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKE 309
D ++++ ++++D + +IM R +++KGL++ + A VK T+++ +P+G E
Sbjct: 17 DQIKKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAIPDGSE 76
Query: 310 RGKFLALDLGGTNFRVLIINL---GENHFDMQSKIYAIPKHIMTGTGIALFDHIAECLAN 480
G+FL+LDLGG+ FRVL + + G+ H M+S+ Y P I+ G G LF+++A+CLA+
Sbjct: 77 NGEFLSLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIRGNGTELFEYVADCLAD 136
Query: 481 FMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARR 660
FMK + ++L LG TFSFP +Q L +GVL WTK F GV DVV L A+ R
Sbjct: 137 FMKTKDLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGVQDTDVVSRLTKAMRRH 196
Query: 661 GDVQIDICAILNDTTGTLMSCAWKNHNCXI 750
D+ +DI A++NDT GT+M+CA+ + C +
Sbjct: 197 KDMDVDILALVNDTVGTMMTCAYDDPYCEV 226
>BC110504-1|AAI10505.1| 917|Homo sapiens hexokinase domain containing
1 protein.
Length = 917
Score = 201 bits (491), Expect = 2e-51
Identities = 93/198 (46%), Positives = 134/198 (67%), Gaps = 2/198 (1%)
Frame = +1
Query: 163 VLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKERGKFLALDLGG 342
+ ++T +Q+ ++ ++ +L+ GL + H ATV+ TY+ LP+G E+GKFLALDLGG
Sbjct: 476 LFQLTREQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGG 535
Query: 343 TNFRVLIINL--GENHFDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERL 516
TNFRVL++ + G M +KI+AIP IM GTG LFDHI +C+A+F+ G+ L
Sbjct: 536 TNFRVLLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASL 595
Query: 517 ALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARRGDVQIDICAILN 696
LGFTFSFP +Q+ + KG L WTKGF + GEDVV L++AI RR + +DI A++N
Sbjct: 596 PLGFTFSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVN 655
Query: 697 DTTGTLMSCAWKNHNCXI 750
DT GT+M+C +++ NC I
Sbjct: 656 DTVGTMMTCGYEDPNCEI 673
Score = 178 bits (434), Expect = 2e-44
Identities = 83/210 (39%), Positives = 133/210 (63%), Gaps = 3/210 (1%)
Frame = +1
Query: 130 DNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKE 309
D ++++ ++++D + +IM R +++KGL++ + A VK T+++ +P+G E
Sbjct: 17 DQIKKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAIPDGSE 76
Query: 310 RGKFLALDLGGTNFRVLIINL---GENHFDMQSKIYAIPKHIMTGTGIALFDHIAECLAN 480
G+FL+LDLGG+ FRVL + + G+ H M+S+ Y P I+ G G LF+++A+CLA+
Sbjct: 77 NGEFLSLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIRGNGTELFEYVADCLAD 136
Query: 481 FMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARR 660
FMK + ++L LG TFSFP +Q L +GVL WTK F GV DVV L A+ R
Sbjct: 137 FMKTKDLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGVQDTDVVSRLTKAMRRH 196
Query: 661 GDVQIDICAILNDTTGTLMSCAWKNHNCXI 750
D+ +DI A++NDT GT+M+CA+ + C +
Sbjct: 197 KDMDVDILALVNDTVGTMMTCAYDDPYCEV 226
>BC012337-1|AAH12337.1| 677|Homo sapiens HKDC1 protein protein.
Length = 677
Score = 201 bits (491), Expect = 2e-51
Identities = 93/198 (46%), Positives = 134/198 (67%), Gaps = 2/198 (1%)
Frame = +1
Query: 163 VLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKERGKFLALDLGG 342
+ ++T +Q+ ++ ++ +L+ GL + H ATV+ TY+ LP+G E+GKFLALDLGG
Sbjct: 236 LFQLTREQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGG 295
Query: 343 TNFRVLIINL--GENHFDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERL 516
TNFRVL++ + G M +KI+AIP IM GTG LFDHI +C+A+F+ G+ L
Sbjct: 296 TNFRVLLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASL 355
Query: 517 ALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARRGDVQIDICAILN 696
LGFTFSFP +Q+ + KG L WTKGF + GEDVV L++AI RR + +DI A++N
Sbjct: 356 PLGFTFSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVN 415
Query: 697 DTTGTLMSCAWKNHNCXI 750
DT GT+M+C +++ NC I
Sbjct: 416 DTVGTMMTCGYEDPNCEI 433
>AL596223-3|CAH71500.1| 917|Homo sapiens hexokinase domain containing
1 protein.
Length = 917
Score = 201 bits (491), Expect = 2e-51
Identities = 93/198 (46%), Positives = 134/198 (67%), Gaps = 2/198 (1%)
Frame = +1
Query: 163 VLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKERGKFLALDLGG 342
+ ++T +Q+ ++ ++ +L+ GL + H ATV+ TY+ LP+G E+GKFLALDLGG
Sbjct: 476 LFQLTREQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGG 535
Query: 343 TNFRVLIINL--GENHFDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERL 516
TNFRVL++ + G M +KI+AIP IM GTG LFDHI +C+A+F+ G+ L
Sbjct: 536 TNFRVLLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASL 595
Query: 517 ALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARRGDVQIDICAILN 696
LGFTFSFP +Q+ + KG L WTKGF + GEDVV L++AI RR + +DI A++N
Sbjct: 596 PLGFTFSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVN 655
Query: 697 DTTGTLMSCAWKNHNCXI 750
DT GT+M+C +++ NC I
Sbjct: 656 DTVGTMMTCGYEDPNCEI 673
Score = 178 bits (434), Expect = 2e-44
Identities = 83/210 (39%), Positives = 133/210 (63%), Gaps = 3/210 (1%)
Frame = +1
Query: 130 DNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKE 309
D ++++ ++++D + +IM R +++KGL++ + A VK T+++ +P+G E
Sbjct: 17 DQIKKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAIPDGSE 76
Query: 310 RGKFLALDLGGTNFRVLIINL---GENHFDMQSKIYAIPKHIMTGTGIALFDHIAECLAN 480
G+FL+LDLGG+ FRVL + + G+ H M+S+ Y P I+ G G LF+++A+CLA+
Sbjct: 77 NGEFLSLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIRGNGTELFEYVADCLAD 136
Query: 481 FMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARR 660
FMK + ++L LG TFSFP +Q L +GVL WTK F GV DVV L A+ R
Sbjct: 137 FMKTKDLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGVQDTDVVSRLTKAMRRH 196
Query: 661 GDVQIDICAILNDTTGTLMSCAWKNHNCXI 750
D+ +DI A++NDT GT+M+CA+ + C +
Sbjct: 197 KDMDVDILALVNDTVGTMMTCAYDDPYCEV 226
>AK026414-1|BAB15478.1| 325|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22761 fis, clone KAIA0893. ).
Length = 325
Score = 201 bits (491), Expect = 2e-51
Identities = 93/198 (46%), Positives = 134/198 (67%), Gaps = 2/198 (1%)
Frame = +1
Query: 163 VLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKERGKFLALDLGG 342
+ ++T +Q+ ++ ++ +L+ GL + H ATV+ TY+ LP+G E+GKFLALDLGG
Sbjct: 65 LFQLTREQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGG 124
Query: 343 TNFRVLIINL--GENHFDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERL 516
TNFRVL++ + G M +KI+AIP IM GTG LFDHI +C+A+F+ G+ L
Sbjct: 125 TNFRVLLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASL 184
Query: 517 ALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARRGDVQIDICAILN 696
LGFTFSFP +Q+ + KG L WTKGF + GEDVV L++AI RR + +DI A++N
Sbjct: 185 PLGFTFSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVN 244
Query: 697 DTTGTLMSCAWKNHNCXI 750
DT GT+M+C +++ NC I
Sbjct: 245 DTVGTMMTCGYEDPNCEI 262
>AC104135-1|AAY24209.1| 573|Homo sapiens unknown protein.
Length = 573
Score = 196 bits (479), Expect = 5e-50
Identities = 93/212 (43%), Positives = 142/212 (66%), Gaps = 3/212 (1%)
Frame = +1
Query: 124 VVDNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNG 303
+ D + ++ E L+++ Q+ E+ R+ ++++GLS+ H A VK TY+ P+G
Sbjct: 119 LADQHRARQKTLEHLQLSHDQLLEVKRRMKVEMERGLSKETHASAPVKMLPTYVCATPDG 178
Query: 304 KERGKFLALDLGGTNFRVLIINLGENHF---DMQSKIYAIPKHIMTGTGIALFDHIAECL 474
E+G FLALDLGGTNFRVL++ + + +M +KIYAIP+ +M GTG LFDHI +C+
Sbjct: 179 TEKGDFLALDLGGTNFRVLLVRVRNGKWGGVEMHNKIYAIPQEVMHGTGDELFDHIVQCI 238
Query: 475 ANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIA 654
A+F++ G+ L LGFTFSFP +Q L + +L +WTKGF SG GEDVV LK+AI
Sbjct: 239 ADFLEYMGMKGVSLPLGFTFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIH 298
Query: 655 RRGDVQIDICAILNDTTGTLMSCAWKNHNCXI 750
RR + +D+ A++NDT GT+M+C +++ +C +
Sbjct: 299 RREEFDLDVVAVVNDTVGTMMTCGFEDPHCEV 330
>M90299-1|AAA52562.1| 465|Homo sapiens glucokinase protein.
Length = 465
Score = 195 bits (476), Expect = 1e-49
Identities = 85/209 (40%), Positives = 144/209 (68%), Gaps = 5/209 (2%)
Frame = +1
Query: 139 QRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKERGK 318
+++ + ++ ++ +K++M R+ ++ +GL H++A+VK TY++ P G E G
Sbjct: 14 EKVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGD 73
Query: 319 FLALDLGGTNFRVLIINLGENH---FDMQSK--IYAIPKHIMTGTGIALFDHIAECLANF 483
FL+LDLGGTNFRV+++ +GE + +++K +Y+IP+ MTGT LFD+I+EC+++F
Sbjct: 74 FLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDF 133
Query: 484 MKEHGVYEERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARRG 663
+ +H + ++L LGFTFSFP++ + KG+L WTKGF SG G +VV L+DAI RRG
Sbjct: 134 LDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRG 193
Query: 664 DVQIDICAILNDTTGTLMSCAWKNHNCXI 750
D ++D+ A++NDT T++SC +++H C +
Sbjct: 194 DFEMDVVAMVNDTVATMISCYYEDHQCEV 222
>M88011-1|AAA51824.1| 465|Homo sapiens glucokinase protein.
Length = 465
Score = 195 bits (476), Expect = 1e-49
Identities = 85/209 (40%), Positives = 144/209 (68%), Gaps = 5/209 (2%)
Frame = +1
Query: 139 QRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKERGK 318
+++ + ++ ++ +K++M R+ ++ +GL H++A+VK TY++ P G E G
Sbjct: 14 EKVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGD 73
Query: 319 FLALDLGGTNFRVLIINLGENH---FDMQSK--IYAIPKHIMTGTGIALFDHIAECLANF 483
FL+LDLGGTNFRV+++ +GE + +++K +Y+IP+ MTGT LFD+I+EC+++F
Sbjct: 74 FLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDF 133
Query: 484 MKEHGVYEERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARRG 663
+ +H + ++L LGFTFSFP++ + KG+L WTKGF SG G +VV L+DAI RRG
Sbjct: 134 LDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRG 193
Query: 664 DVQIDICAILNDTTGTLMSCAWKNHNCXI 750
D ++D+ A++NDT T++SC +++H C +
Sbjct: 194 DFEMDVVAMVNDTVATMISCYYEDHQCEV 222
>EU008605-1|ABS31137.1| 465|Homo sapiens glucokinase protein.
Length = 465
Score = 195 bits (476), Expect = 1e-49
Identities = 85/209 (40%), Positives = 144/209 (68%), Gaps = 5/209 (2%)
Frame = +1
Query: 139 QRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKERGK 318
+++ + ++ ++ +K++M R+ ++ +GL H++A+VK TY++ P G E G
Sbjct: 14 EKVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGD 73
Query: 319 FLALDLGGTNFRVLIINLGENH---FDMQSK--IYAIPKHIMTGTGIALFDHIAECLANF 483
FL+LDLGGTNFRV+++ +GE + +++K +Y+IP+ MTGT LFD+I+EC+++F
Sbjct: 74 FLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDF 133
Query: 484 MKEHGVYEERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARRG 663
+ +H + ++L LGFTFSFP++ + KG+L WTKGF SG G +VV L+DAI RRG
Sbjct: 134 LDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRG 193
Query: 664 DVQIDICAILNDTTGTLMSCAWKNHNCXI 750
D ++D+ A++NDT T++SC +++H C +
Sbjct: 194 DFEMDVVAMVNDTVATMISCYYEDHQCEV 222
>BT007062-1|AAP35711.1| 465|Homo sapiens glucokinase (hexokinase 4,
maturity onset diabetes of the young 2) protein.
Length = 465
Score = 195 bits (476), Expect = 1e-49
Identities = 85/209 (40%), Positives = 144/209 (68%), Gaps = 5/209 (2%)
Frame = +1
Query: 139 QRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKERGK 318
+++ + ++ ++ +K++M R+ ++ +GL H++A+VK TY++ P G E G
Sbjct: 14 EKVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGD 73
Query: 319 FLALDLGGTNFRVLIINLGENH---FDMQSK--IYAIPKHIMTGTGIALFDHIAECLANF 483
FL+LDLGGTNFRV+++ +GE + +++K +Y+IP+ MTGT LFD+I+EC+++F
Sbjct: 74 FLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDF 133
Query: 484 MKEHGVYEERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARRG 663
+ +H + ++L LGFTFSFP++ + KG+L WTKGF SG G +VV L+DAI RRG
Sbjct: 134 LDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRG 193
Query: 664 DVQIDICAILNDTTGTLMSCAWKNHNCXI 750
D ++D+ A++NDT T++SC +++H C +
Sbjct: 194 DFEMDVVAMVNDTVATMISCYYEDHQCEV 222
>BC001890-1|AAH01890.1| 465|Homo sapiens glucokinase (hexokinase 4,
maturity onset diabetes of the young 2) protein.
Length = 465
Score = 195 bits (476), Expect = 1e-49
Identities = 85/209 (40%), Positives = 144/209 (68%), Gaps = 5/209 (2%)
Frame = +1
Query: 139 QRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKERGK 318
+++ + ++ ++ +K++M R+ ++ +GL H++A+VK TY++ P G E G
Sbjct: 14 EKVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGD 73
Query: 319 FLALDLGGTNFRVLIINLGENH---FDMQSK--IYAIPKHIMTGTGIALFDHIAECLANF 483
FL+LDLGGTNFRV+++ +GE + +++K +Y+IP+ MTGT LFD+I+EC+++F
Sbjct: 74 FLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDF 133
Query: 484 MKEHGVYEERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARRG 663
+ +H + ++L LGFTFSFP++ + KG+L WTKGF SG G +VV L+DAI RRG
Sbjct: 134 LDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRG 193
Query: 664 DVQIDICAILNDTTGTLMSCAWKNHNCXI 750
D ++D+ A++NDT T++SC +++H C +
Sbjct: 194 DFEMDVVAMVNDTVATMISCYYEDHQCEV 222
>AF041022-1|AAB97680.1| 465|Homo sapiens glucokinase protein.
Length = 465
Score = 195 bits (476), Expect = 1e-49
Identities = 85/209 (40%), Positives = 144/209 (68%), Gaps = 5/209 (2%)
Frame = +1
Query: 139 QRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKERGK 318
+++ + ++ ++ +K++M R+ ++ +GL H++A+VK TY++ P G E G
Sbjct: 14 EKVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGD 73
Query: 319 FLALDLGGTNFRVLIINLGENH---FDMQSK--IYAIPKHIMTGTGIALFDHIAECLANF 483
FL+LDLGGTNFRV+++ +GE + +++K +Y+IP+ MTGT LFD+I+EC+++F
Sbjct: 74 FLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDF 133
Query: 484 MKEHGVYEERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARRG 663
+ +H + ++L LGFTFSFP++ + KG+L WTKGF SG G +VV L+DAI RRG
Sbjct: 134 LDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRG 193
Query: 664 DVQIDICAILNDTTGTLMSCAWKNHNCXI 750
D ++D+ A++NDT T++SC +++H C +
Sbjct: 194 DFEMDVVAMVNDTVATMISCYYEDHQCEV 222
>AF041022-3|AAB97682.1| 464|Homo sapiens glucokinase protein.
Length = 464
Score = 194 bits (474), Expect = 2e-49
Identities = 85/199 (42%), Positives = 140/199 (70%), Gaps = 5/199 (2%)
Frame = +1
Query: 169 KMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKERGKFLALDLGGTN 348
++ ++ +K++M R+ ++ +GL H++A+VK TY++ P G E G FL+LDLGGTN
Sbjct: 23 QLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDFLSLDLGGTN 82
Query: 349 FRVLIINLGENH---FDMQSK--IYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEER 513
FRV+++ +GE + +++K +Y+IP+ MTGT LFD+I+EC+++F+ +H + ++
Sbjct: 83 FRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFLDKHQMKHKK 142
Query: 514 LALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARRGDVQIDICAIL 693
L LGFTFSFP++ + KG+L WTKGF SG G +VV L+DAI RRGD ++D+ A++
Sbjct: 143 LPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRGDFEMDVVAMV 202
Query: 694 NDTTGTLMSCAWKNHNCXI 750
NDT T++SC +++H C +
Sbjct: 203 NDTVATMISCYYEDHQCEV 221
>AF041022-2|AAB97681.1| 466|Homo sapiens glucokinase protein.
Length = 466
Score = 194 bits (474), Expect = 2e-49
Identities = 85/199 (42%), Positives = 140/199 (70%), Gaps = 5/199 (2%)
Frame = +1
Query: 169 KMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKERGKFLALDLGGTN 348
++ ++ +K++M R+ ++ +GL H++A+VK TY++ P G E G FL+LDLGGTN
Sbjct: 25 QLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDFLSLDLGGTN 84
Query: 349 FRVLIINLGENH---FDMQSK--IYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEER 513
FRV+++ +GE + +++K +Y+IP+ MTGT LFD+I+EC+++F+ +H + ++
Sbjct: 85 FRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFLDKHQMKHKK 144
Query: 514 LALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARRGDVQIDICAIL 693
L LGFTFSFP++ + KG+L WTKGF SG G +VV L+DAI RRGD ++D+ A++
Sbjct: 145 LPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRGDFEMDVVAMV 204
Query: 694 NDTTGTLMSCAWKNHNCXI 750
NDT T++SC +++H C +
Sbjct: 205 NDTVATMISCYYEDHQCEV 223
>M69051-1|AAB59563.1| 464|Homo sapiens glucokinase protein.
Length = 464
Score = 194 bits (472), Expect = 4e-49
Identities = 85/199 (42%), Positives = 139/199 (69%), Gaps = 5/199 (2%)
Frame = +1
Query: 169 KMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKERGKFLALDLGGTN 348
++ ++ +K++M R+ ++ +GL H++A+VK TY++ P G E G FL+LDLGGTN
Sbjct: 23 QLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDFLSLDLGGTN 82
Query: 349 FRVLIINLGENH---FDMQSK--IYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEER 513
FRV+++ +GE + +++K Y+IP+ MTGT LFD+I+EC+++F+ +H + ++
Sbjct: 83 FRVMLVKVGEGEEGQWSVKTKHQTYSIPEDAMTGTAEMLFDYISECISDFLDKHQMKHKK 142
Query: 514 LALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARRGDVQIDICAIL 693
L LGFTFSFP++ + KG+L WTKGF SG G +VV L+DAI RRGD ++D+ A++
Sbjct: 143 LPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRGDFEMDVVAMV 202
Query: 694 NDTTGTLMSCAWKNHNCXI 750
NDT T++SC +++H C +
Sbjct: 203 NDTVATMISCYYEDHQCEV 221
>BC021278-1|AAH21278.1| 427|Homo sapiens HKDC1 protein protein.
Length = 427
Score = 193 bits (471), Expect = 5e-49
Identities = 91/180 (50%), Positives = 123/180 (68%), Gaps = 2/180 (1%)
Frame = +1
Query: 217 DLKKGLSRADHDKATVKCWITYIQDLPNGKERGKFLALDLGGTNFRVLIINL--GENHFD 390
+L+ GL + H ATV+ TY+ LP+G E+GKFLALDLGGTNFRVL++ + G
Sbjct: 4 ELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGGTNFRVLLVKIRSGRRSVR 63
Query: 391 MQSKIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKG 570
M +KI+AIP IM GTG LFDHI +C+A+F+ G+ L LGFTFSFP +Q+ + KG
Sbjct: 64 MYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASLPLGFTFSFPCRQMSIDKG 123
Query: 571 VLQRWTKGFSCSGVVGEDVVQGLKDAIARRGDVQIDICAILNDTTGTLMSCAWKNHNCXI 750
L WTKGF + GEDVV L++AI RR + +DI A++NDT GT+M+C +++ NC I
Sbjct: 124 TLIGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGTMMTCGYEDPNCEI 183
>X66957-1|CAA47379.1| 631|Homo sapiens hexokinase type 1 protein.
Length = 631
Score = 189 bits (461), Expect = 8e-48
Identities = 90/207 (43%), Positives = 132/207 (63%), Gaps = 3/207 (1%)
Frame = +1
Query: 139 QRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKERGK 318
++I E +T + E+ R+ +++ GL + H+ A VK ++++ P+G E G
Sbjct: 182 RQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGD 241
Query: 319 FLALDLGGTNFRVLIINL--GENH-FDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMK 489
FLALDLGGTNFRVL++ + G+ +M +KIYAIP IM GTG LFDHI C+++F+
Sbjct: 242 FLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLD 301
Query: 490 EHGVYEERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARRGDV 669
G+ R+ LGFTFSFP +Q L G+L WTKGF + VG DVV L+DAI RR +
Sbjct: 302 YMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRREEF 361
Query: 670 QIDICAILNDTTGTLMSCAWKNHNCXI 750
+D+ A++NDT GT+M+CA++ C +
Sbjct: 362 DLDVVAVVNDTVGTMMTCAYEEPTCEV 388
>M75126-1|AAA52646.1| 917|Homo sapiens hexokinase 1 protein.
Length = 917
Score = 189 bits (461), Expect = 8e-48
Identities = 84/210 (40%), Positives = 142/210 (67%), Gaps = 3/210 (1%)
Frame = +1
Query: 130 DNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKE 309
D +++I + ++++D+ + +IM R ++K GLSR + ATVK T+++ +P+G E
Sbjct: 17 DQVKKIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSE 76
Query: 310 RGKFLALDLGGTNFRVLIINLGEN---HFDMQSKIYAIPKHIMTGTGIALFDHIAECLAN 480
+G F+ALDLGG++FR+L + + + M+S++Y P++I+ G+G LFDH+AECL +
Sbjct: 77 KGDFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGD 136
Query: 481 FMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARR 660
FM++ + +++L +GFTFSFP +Q + + +L WTK F SGV G DVV+ L AI +R
Sbjct: 137 FMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKR 196
Query: 661 GDVQIDICAILNDTTGTLMSCAWKNHNCXI 750
GD +I A++NDT GT+M+C + + +C +
Sbjct: 197 GDYDANIVAVVNDTVGTMMTCGYDDQHCEV 226
Score = 189 bits (461), Expect = 8e-48
Identities = 90/207 (43%), Positives = 132/207 (63%), Gaps = 3/207 (1%)
Frame = +1
Query: 139 QRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKERGK 318
++I E +T + E+ R+ +++ GL + H+ A VK ++++ P+G E G
Sbjct: 468 RQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGD 527
Query: 319 FLALDLGGTNFRVLIINL--GENH-FDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMK 489
FLALDLGGTNFRVL++ + G+ +M +KIYAIP IM GTG LFDHI C+++F+
Sbjct: 528 FLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLD 587
Query: 490 EHGVYEERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARRGDV 669
G+ R+ LGFTFSFP +Q L G+L WTKGF + VG DVV L+DAI RR +
Sbjct: 588 YMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRREEF 647
Query: 670 QIDICAILNDTTGTLMSCAWKNHNCXI 750
+D+ A++NDT GT+M+CA++ C +
Sbjct: 648 DLDVVAVVNDTVGTMMTCAYEEPTCEV 674
>BC008730-1|AAH08730.1| 917|Homo sapiens hexokinase 1 protein.
Length = 917
Score = 189 bits (461), Expect = 8e-48
Identities = 84/210 (40%), Positives = 142/210 (67%), Gaps = 3/210 (1%)
Frame = +1
Query: 130 DNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKE 309
D +++I + ++++D+ + +IM R ++K GLSR + ATVK T+++ +P+G E
Sbjct: 17 DQVKKIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSE 76
Query: 310 RGKFLALDLGGTNFRVLIINLGEN---HFDMQSKIYAIPKHIMTGTGIALFDHIAECLAN 480
+G F+ALDLGG++FR+L + + + M+S++Y P++I+ G+G LFDH+AECL +
Sbjct: 77 KGDFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGD 136
Query: 481 FMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARR 660
FM++ + +++L +GFTFSFP +Q + + +L WTK F SGV G DVV+ L AI +R
Sbjct: 137 FMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKR 196
Query: 661 GDVQIDICAILNDTTGTLMSCAWKNHNCXI 750
GD +I A++NDT GT+M+C + + +C +
Sbjct: 197 GDYDANIVAVVNDTVGTMMTCGYDDQHCEV 226
Score = 189 bits (461), Expect = 8e-48
Identities = 90/207 (43%), Positives = 132/207 (63%), Gaps = 3/207 (1%)
Frame = +1
Query: 139 QRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKERGK 318
++I E +T + E+ R+ +++ GL + H+ A VK ++++ P+G E G
Sbjct: 468 RQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGD 527
Query: 319 FLALDLGGTNFRVLIINL--GENH-FDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMK 489
FLALDLGGTNFRVL++ + G+ +M +KIYAIP IM GTG LFDHI C+++F+
Sbjct: 528 FLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLD 587
Query: 490 EHGVYEERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARRGDV 669
G+ R+ LGFTFSFP +Q L G+L WTKGF + VG DVV L+DAI RR +
Sbjct: 588 YMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRREEF 647
Query: 670 QIDICAILNDTTGTLMSCAWKNHNCXI 750
+D+ A++NDT GT+M+CA++ C +
Sbjct: 648 DLDVVAVVNDTVGTMMTCAYEEPTCEV 674
>AL596223-9|CAH71506.1| 917|Homo sapiens hexokinase 1 protein.
Length = 917
Score = 189 bits (461), Expect = 8e-48
Identities = 84/210 (40%), Positives = 142/210 (67%), Gaps = 3/210 (1%)
Frame = +1
Query: 130 DNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKE 309
D +++I + ++++D+ + +IM R ++K GLSR + ATVK T+++ +P+G E
Sbjct: 17 DQVKKIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSE 76
Query: 310 RGKFLALDLGGTNFRVLIINLGEN---HFDMQSKIYAIPKHIMTGTGIALFDHIAECLAN 480
+G F+ALDLGG++FR+L + + + M+S++Y P++I+ G+G LFDH+AECL +
Sbjct: 77 KGDFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGD 136
Query: 481 FMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARR 660
FM++ + +++L +GFTFSFP +Q + + +L WTK F SGV G DVV+ L AI +R
Sbjct: 137 FMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKR 196
Query: 661 GDVQIDICAILNDTTGTLMSCAWKNHNCXI 750
GD +I A++NDT GT+M+C + + +C +
Sbjct: 197 GDYDANIVAVVNDTVGTMMTCGYDDQHCEV 226
Score = 189 bits (461), Expect = 8e-48
Identities = 90/207 (43%), Positives = 132/207 (63%), Gaps = 3/207 (1%)
Frame = +1
Query: 139 QRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKERGK 318
++I E +T + E+ R+ +++ GL + H+ A VK ++++ P+G E G
Sbjct: 468 RQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGD 527
Query: 319 FLALDLGGTNFRVLIINL--GENH-FDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMK 489
FLALDLGGTNFRVL++ + G+ +M +KIYAIP IM GTG LFDHI C+++F+
Sbjct: 528 FLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLD 587
Query: 490 EHGVYEERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARRGDV 669
G+ R+ LGFTFSFP +Q L G+L WTKGF + VG DVV L+DAI RR +
Sbjct: 588 YMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRREEF 647
Query: 670 QIDICAILNDTTGTLMSCAWKNHNCXI 750
+D+ A++NDT GT+M+CA++ C +
Sbjct: 648 DLDVVAVVNDTVGTMMTCAYEEPTCEV 674
>AF016365-4|AAC15862.1| 917|Homo sapiens hexokinase I protein.
Length = 917
Score = 189 bits (461), Expect = 8e-48
Identities = 84/210 (40%), Positives = 142/210 (67%), Gaps = 3/210 (1%)
Frame = +1
Query: 130 DNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKE 309
D +++I + ++++D+ + +IM R ++K GLSR + ATVK T+++ +P+G E
Sbjct: 17 DQVKKIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSE 76
Query: 310 RGKFLALDLGGTNFRVLIINLGEN---HFDMQSKIYAIPKHIMTGTGIALFDHIAECLAN 480
+G F+ALDLGG++FR+L + + + M+S++Y P++I+ G+G LFDH+AECL +
Sbjct: 77 KGDFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGD 136
Query: 481 FMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARR 660
FM++ + +++L +GFTFSFP +Q + + +L WTK F SGV G DVV+ L AI +R
Sbjct: 137 FMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKR 196
Query: 661 GDVQIDICAILNDTTGTLMSCAWKNHNCXI 750
GD +I A++NDT GT+M+C + + +C +
Sbjct: 197 GDYDANIVAVVNDTVGTMMTCGYDDQHCEV 226
Score = 189 bits (461), Expect = 8e-48
Identities = 90/207 (43%), Positives = 132/207 (63%), Gaps = 3/207 (1%)
Frame = +1
Query: 139 QRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKERGK 318
++I E +T + E+ R+ +++ GL + H+ A VK ++++ P+G E G
Sbjct: 468 RQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGD 527
Query: 319 FLALDLGGTNFRVLIINL--GENH-FDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMK 489
FLALDLGGTNFRVL++ + G+ +M +KIYAIP IM GTG LFDHI C+++F+
Sbjct: 528 FLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLD 587
Query: 490 EHGVYEERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARRGDV 669
G+ R+ LGFTFSFP +Q L G+L WTKGF + VG DVV L+DAI RR +
Sbjct: 588 YMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRREEF 647
Query: 670 QIDICAILNDTTGTLMSCAWKNHNCXI 750
+D+ A++NDT GT+M+CA++ C +
Sbjct: 648 DLDVVAVVNDTVGTMMTCAYEEPTCEV 674
>AF016365-3|AAC15863.1| 916|Homo sapiens hexokinase IR protein.
Length = 916
Score = 189 bits (461), Expect = 8e-48
Identities = 90/207 (43%), Positives = 132/207 (63%), Gaps = 3/207 (1%)
Frame = +1
Query: 139 QRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKERGK 318
++I E +T + E+ R+ +++ GL + H+ A VK ++++ P+G E G
Sbjct: 467 RQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGD 526
Query: 319 FLALDLGGTNFRVLIINL--GENH-FDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMK 489
FLALDLGGTNFRVL++ + G+ +M +KIYAIP IM GTG LFDHI C+++F+
Sbjct: 527 FLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLD 586
Query: 490 EHGVYEERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARRGDV 669
G+ R+ LGFTFSFP +Q L G+L WTKGF + VG DVV L+DAI RR +
Sbjct: 587 YMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRREEF 646
Query: 670 QIDICAILNDTTGTLMSCAWKNHNCXI 750
+D+ A++NDT GT+M+CA++ C +
Sbjct: 647 DLDVVAVVNDTVGTMMTCAYEEPTCEV 673
Score = 186 bits (453), Expect = 7e-47
Identities = 82/198 (41%), Positives = 136/198 (68%), Gaps = 3/198 (1%)
Frame = +1
Query: 166 LKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKERGKFLALDLGGT 345
++++D+ + +IM R ++K GLSR + ATVK T+++ +P+G E+G F+ALDLGG+
Sbjct: 28 MRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFIALDLGGS 87
Query: 346 NFRVLIINLGEN---HFDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERL 516
+FR+L + + + M+S++Y P++I+ G+G LFDH+AECL +FM++ + +++L
Sbjct: 88 SFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKRKIKDKKL 147
Query: 517 ALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARRGDVQIDICAILN 696
+GFTFSFP +Q + + +L WTK F SGV G DVV+ L AI +RGD +I A++N
Sbjct: 148 PVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDANIVAVVN 207
Query: 697 DTTGTLMSCAWKNHNCXI 750
DT GT+M+C + + +C +
Sbjct: 208 DTVGTMMTCGYDDQHCEV 225
>AF016365-2|AAF82320.1| 905|Homo sapiens hexokinase 1 isoform td
protein.
Length = 905
Score = 189 bits (461), Expect = 8e-48
Identities = 90/207 (43%), Positives = 132/207 (63%), Gaps = 3/207 (1%)
Frame = +1
Query: 139 QRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKERGK 318
++I E +T + E+ R+ +++ GL + H+ A VK ++++ P+G E G
Sbjct: 456 RQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGD 515
Query: 319 FLALDLGGTNFRVLIINL--GENH-FDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMK 489
FLALDLGGTNFRVL++ + G+ +M +KIYAIP IM GTG LFDHI C+++F+
Sbjct: 516 FLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLD 575
Query: 490 EHGVYEERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARRGDV 669
G+ R+ LGFTFSFP +Q L G+L WTKGF + VG DVV L+DAI RR +
Sbjct: 576 YMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRREEF 635
Query: 670 QIDICAILNDTTGTLMSCAWKNHNCXI 750
+D+ A++NDT GT+M+CA++ C +
Sbjct: 636 DLDVVAVVNDTVGTMMTCAYEEPTCEV 662
Score = 186 bits (453), Expect = 7e-47
Identities = 82/198 (41%), Positives = 136/198 (68%), Gaps = 3/198 (1%)
Frame = +1
Query: 166 LKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKERGKFLALDLGGT 345
++++D+ + +IM R ++K GLSR + ATVK T+++ +P+G E+G F+ALDLGG+
Sbjct: 17 MRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFIALDLGGS 76
Query: 346 NFRVLIINLGEN---HFDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERL 516
+FR+L + + + M+S++Y P++I+ G+G LFDH+AECL +FM++ + +++L
Sbjct: 77 SFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKRKIKDKKL 136
Query: 517 ALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARRGDVQIDICAILN 696
+GFTFSFP +Q + + +L WTK F SGV G DVV+ L AI +RGD +I A++N
Sbjct: 137 PVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDANIVAVVN 196
Query: 697 DTTGTLMSCAWKNHNCXI 750
DT GT+M+C + + +C +
Sbjct: 197 DTVGTMMTCGYDDQHCEV 214
>AF016365-1|AAF82319.1| 921|Homo sapiens hexokinase 1 isoform ta/tb
protein.
Length = 921
Score = 189 bits (461), Expect = 8e-48
Identities = 90/207 (43%), Positives = 132/207 (63%), Gaps = 3/207 (1%)
Frame = +1
Query: 139 QRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKERGK 318
++I E +T + E+ R+ +++ GL + H+ A VK ++++ P+G E G
Sbjct: 472 RQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGD 531
Query: 319 FLALDLGGTNFRVLIINL--GENH-FDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMK 489
FLALDLGGTNFRVL++ + G+ +M +KIYAIP IM GTG LFDHI C+++F+
Sbjct: 532 FLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLD 591
Query: 490 EHGVYEERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARRGDV 669
G+ R+ LGFTFSFP +Q L G+L WTKGF + VG DVV L+DAI RR +
Sbjct: 592 YMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRREEF 651
Query: 670 QIDICAILNDTTGTLMSCAWKNHNCXI 750
+D+ A++NDT GT+M+CA++ C +
Sbjct: 652 DLDVVAVVNDTVGTMMTCAYEEPTCEV 678
Score = 186 bits (453), Expect = 7e-47
Identities = 82/198 (41%), Positives = 136/198 (68%), Gaps = 3/198 (1%)
Frame = +1
Query: 166 LKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKERGKFLALDLGGT 345
++++D+ + +IM R ++K GLSR + ATVK T+++ +P+G E+G F+ALDLGG+
Sbjct: 33 MRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFIALDLGGS 92
Query: 346 NFRVLIINLGEN---HFDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERL 516
+FR+L + + + M+S++Y P++I+ G+G LFDH+AECL +FM++ + +++L
Sbjct: 93 SFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKRKIKDKKL 152
Query: 517 ALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARRGDVQIDICAILN 696
+GFTFSFP +Q + + +L WTK F SGV G DVV+ L AI +RGD +I A++N
Sbjct: 153 PVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDANIVAVVN 212
Query: 697 DTTGTLMSCAWKNHNCXI 750
DT GT+M+C + + +C +
Sbjct: 213 DTVGTMMTCGYDDQHCEV 230
>AB209526-1|BAD92763.1| 949|Homo sapiens hexokinase 1 isoform HKI
variant protein.
Length = 949
Score = 189 bits (461), Expect = 8e-48
Identities = 84/210 (40%), Positives = 142/210 (67%), Gaps = 3/210 (1%)
Frame = +1
Query: 130 DNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKE 309
D +++I + ++++D+ + +IM R ++K GLSR + ATVK T+++ +P+G E
Sbjct: 49 DQVKKIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSE 108
Query: 310 RGKFLALDLGGTNFRVLIINLGEN---HFDMQSKIYAIPKHIMTGTGIALFDHIAECLAN 480
+G F+ALDLGG++FR+L + + + M+S++Y P++I+ G+G LFDH+AECL +
Sbjct: 109 KGDFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGD 168
Query: 481 FMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARR 660
FM++ + +++L +GFTFSFP +Q + + +L WTK F SGV G DVV+ L AI +R
Sbjct: 169 FMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKR 228
Query: 661 GDVQIDICAILNDTTGTLMSCAWKNHNCXI 750
GD +I A++NDT GT+M+C + + +C +
Sbjct: 229 GDYDANIVAVVNDTVGTMMTCGYDDQHCEV 258
Score = 189 bits (461), Expect = 8e-48
Identities = 90/207 (43%), Positives = 132/207 (63%), Gaps = 3/207 (1%)
Frame = +1
Query: 139 QRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKERGK 318
++I E +T + E+ R+ +++ GL + H+ A VK ++++ P+G E G
Sbjct: 500 RQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGD 559
Query: 319 FLALDLGGTNFRVLIINL--GENH-FDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMK 489
FLALDLGGTNFRVL++ + G+ +M +KIYAIP IM GTG LFDHI C+++F+
Sbjct: 560 FLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLD 619
Query: 490 EHGVYEERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARRGDV 669
G+ R+ LGFTFSFP +Q L G+L WTKGF + VG DVV L+DAI RR +
Sbjct: 620 YMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRREEF 679
Query: 670 QIDICAILNDTTGTLMSCAWKNHNCXI 750
+D+ A++NDT GT+M+CA++ C +
Sbjct: 680 DLDVVAVVNDTVGTMMTCAYEEPTCEV 706
>AL596223-8|CAH71505.1| 291|Homo sapiens hexokinase 1 protein.
Length = 291
Score = 186 bits (453), Expect = 7e-47
Identities = 82/198 (41%), Positives = 136/198 (68%), Gaps = 3/198 (1%)
Frame = +1
Query: 166 LKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKERGKFLALDLGGT 345
++++D+ + +IM R ++K GLSR + ATVK T+++ +P+G E+G F+ALDLGG+
Sbjct: 28 MRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFIALDLGGS 87
Query: 346 NFRVLIINLGEN---HFDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERL 516
+FR+L + + + M+S++Y P++I+ G+G LFDH+AECL +FM++ + +++L
Sbjct: 88 SFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKRKIKDKKL 147
Query: 517 ALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARRGDVQIDICAILN 696
+GFTFSFP +Q + + +L WTK F SGV G DVV+ L AI +RGD +I A++N
Sbjct: 148 PVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDANIVAVVN 207
Query: 697 DTTGTLMSCAWKNHNCXI 750
DT GT+M+C + + +C +
Sbjct: 208 DTVGTMMTCGYDDQHCEV 225
>U51333-1|AAC50732.1| 923|Homo sapiens hexokinase III protein.
Length = 923
Score = 178 bits (434), Expect = 2e-44
Identities = 83/202 (41%), Positives = 131/202 (64%)
Frame = +1
Query: 145 IREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKERGKFL 324
+ E ++ Q+ + ++ + KGL + ++++ T+++ P+G ERG FL
Sbjct: 483 LEETLAPFRLNHDQLAAVQAQMRKAMAKGLRG---EASSLRMLPTFVRATPDGSERGDFL 539
Query: 325 ALDLGGTNFRVLIINLGENHFDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVY 504
ALDLGGTNFRVL++ + + S+IY+IP+ + G+G LFDHI +C+ +F ++ G+
Sbjct: 540 ALDLGGTNFRVLLVRVTTG-VQITSEIYSIPETVAQGSGQQLFDHIVDCIVDFQQKQGLS 598
Query: 505 EERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARRGDVQIDIC 684
+ L LGFTFSFP +QLGL +G+L WTKGF S G+DVV L++AI RR V++++
Sbjct: 599 GQSLPLGFTFSFPCRQLGLDQGILLNWTKGFKASDCEGQDVVSLLREAITRRQAVELNVV 658
Query: 685 AILNDTTGTLMSCAWKNHNCXI 750
AI+NDT GT+MSC +++ C I
Sbjct: 659 AIVNDTVGTMMSCGYEDPRCEI 680
Score = 157 bits (381), Expect = 4e-38
Identities = 82/203 (40%), Positives = 121/203 (59%), Gaps = 5/203 (2%)
Frame = +1
Query: 130 DNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKE 309
D+ + ++E + K+T Q+++I L +++ L V+ TY+ P+G E
Sbjct: 28 DSSELVQECLQQFKVTRAQLQQIQASLLGSMEQALRGQASPAPAVRMLPTYVGSTPHGTE 87
Query: 310 RGKFLALDLG--GTNFRVLIINLG--ENH-FDMQSKIYAIPKHIMTGTGIALFDHIAECL 474
+G F+ L+LG G + RVL + L E H + +S+ + IP+ +M G G LFD A CL
Sbjct: 88 QGDFVVLELGATGASLRVLWVTLTGIEGHRVEPRSQEFVIPQEVMLGAGQQLFDFAAHCL 147
Query: 475 ANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIA 654
+ F+ V ++ L LGF+FSFP Q GL + L WTKGF CSGV G+DVVQ L+DAI
Sbjct: 148 SEFLDAQPVNKQGLQLGFSFSFPCHQTGLDRSTLISWTKGFRCSGVEGQDVVQLLRDAIR 207
Query: 655 RRGDVQIDICAILNDTTGTLMSC 723
R+G ID+ A++NDT GT+M C
Sbjct: 208 RQGAYNIDVVAVVNDTVGTMMGC 230
>BC028129-1|AAH28129.1| 923|Homo sapiens hexokinase 3 (white cell)
protein.
Length = 923
Score = 178 bits (434), Expect = 2e-44
Identities = 83/202 (41%), Positives = 131/202 (64%)
Frame = +1
Query: 145 IREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKERGKFL 324
+ E ++ Q+ + ++ + KGL + ++++ T+++ P+G ERG FL
Sbjct: 483 LEETLAPFRLNHDQLAAVQAQMRKAMAKGLRG---EASSLRMLPTFVRATPDGSERGDFL 539
Query: 325 ALDLGGTNFRVLIINLGENHFDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVY 504
ALDLGGTNFRVL++ + + S+IY+IP+ + G+G LFDHI +C+ +F ++ G+
Sbjct: 540 ALDLGGTNFRVLLVRVTTG-VQITSEIYSIPETVAQGSGQQLFDHIVDCIVDFQQKQGLS 598
Query: 505 EERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARRGDVQIDIC 684
+ L LGFTFSFP +QLGL +G+L WTKGF S G+DVV L++AI RR V++++
Sbjct: 599 GQSLPLGFTFSFPCRQLGLDQGILLNWTKGFKASDCEGQDVVSLLREAITRRQAVELNVV 658
Query: 685 AILNDTTGTLMSCAWKNHNCXI 750
AI+NDT GT+MSC +++ C I
Sbjct: 659 AIVNDTVGTMMSCGYEDPRCEI 680
Score = 157 bits (381), Expect = 4e-38
Identities = 82/203 (40%), Positives = 121/203 (59%), Gaps = 5/203 (2%)
Frame = +1
Query: 130 DNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKE 309
D+ + ++E + K+T Q+++I L +++ L V+ TY+ P+G E
Sbjct: 28 DSSELVQECLQQFKVTRAQLQQIQASLLGSMEQALRGQASPAPAVRMLPTYVGSTPHGTE 87
Query: 310 RGKFLALDLG--GTNFRVLIINLG--ENH-FDMQSKIYAIPKHIMTGTGIALFDHIAECL 474
+G F+ L+LG G + RVL + L E H + +S+ + IP+ +M G G LFD A CL
Sbjct: 88 QGDFVVLELGATGASLRVLWVTLTGIEGHRVEPRSQEFVIPQEVMLGAGQQLFDFAAHCL 147
Query: 475 ANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIA 654
+ F+ V ++ L LGF+FSFP Q GL + L WTKGF CSGV G+DVVQ L+DAI
Sbjct: 148 SEFLDAQPVNKQGLQLGFSFSFPCHQTGLDRSTLISWTKGFRCSGVEGQDVVQLLRDAIR 207
Query: 655 RRGDVQIDICAILNDTTGTLMSC 723
R+G ID+ A++NDT GT+M C
Sbjct: 208 RQGAYNIDVVAVVNDTVGTMMGC 230
>AB208951-1|BAD92188.1| 960|Homo sapiens Hexokinase 3 variant
protein.
Length = 960
Score = 178 bits (434), Expect = 2e-44
Identities = 83/202 (41%), Positives = 131/202 (64%)
Frame = +1
Query: 145 IREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKERGKFL 324
+ E ++ Q+ + ++ + KGL + ++++ T+++ P+G ERG FL
Sbjct: 453 LEETLAPFRLNHDQLAAVQAQMRKAMAKGLRG---EASSLRMLPTFVRATPDGSERGDFL 509
Query: 325 ALDLGGTNFRVLIINLGENHFDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVY 504
ALDLGGTNFRVL++ + + S+IY+IP+ + G+G LFDHI +C+ +F ++ G+
Sbjct: 510 ALDLGGTNFRVLLVRVTTG-VQITSEIYSIPETVAQGSGQQLFDHIVDCIVDFQQKQGLS 568
Query: 505 EERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARRGDVQIDIC 684
+ L LGFTFSFP +QLGL +G+L WTKGF S G+DVV L++AI RR V++++
Sbjct: 569 GQSLPLGFTFSFPCRQLGLDQGILLNWTKGFKASDCEGQDVVSLLREAITRRQAVELNVV 628
Query: 685 AILNDTTGTLMSCAWKNHNCXI 750
AI+NDT GT+MSC +++ C I
Sbjct: 629 AIVNDTVGTMMSCGYEDPRCEI 650
Score = 157 bits (381), Expect = 4e-38
Identities = 82/203 (40%), Positives = 121/203 (59%), Gaps = 5/203 (2%)
Frame = +1
Query: 130 DNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKE 309
D+ + ++E + K+T Q+++I L +++ L V+ TY+ P+G E
Sbjct: 40 DSSELVQECLQQFKVTRAQLQQIQASLLGSMEQALRGQASPAPAVRMLPTYVGSTPHGTE 99
Query: 310 RGKFLALDLG--GTNFRVLIINLG--ENH-FDMQSKIYAIPKHIMTGTGIALFDHIAECL 474
+G F+ L+LG G + RVL + L E H + +S+ + IP+ +M G G LFD A CL
Sbjct: 100 QGDFVVLELGATGASLRVLWVTLTGIEGHRVEPRSQEFVIPQEVMLGAGQQLFDFAAHCL 159
Query: 475 ANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIA 654
+ F+ V ++ L LGF+FSFP Q GL + L WTKGF CSGV G+DVVQ L+DAI
Sbjct: 160 SEFLDAQPVNKQGLQLGFSFSFPCHQTGLDRSTLISWTKGFRCSGVEGQDVVQLLRDAIR 219
Query: 655 RRGDVQIDICAILNDTTGTLMSC 723
R+G ID+ A++NDT GT+M C
Sbjct: 220 RQGAYNIDVVAVVNDTVGTMMGC 242
>U42303-1|AAC50422.1| 566|Homo sapiens ATP:D-hexose
6-phosphotransferase protein.
Length = 566
Score = 167 bits (407), Expect = 3e-41
Identities = 78/202 (38%), Positives = 127/202 (62%)
Frame = +1
Query: 145 IREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKERGKFL 324
+ E ++ Q+ + ++ + +G ++ + ++ + T+++ G ERG FL
Sbjct: 126 LEETLAPFRLNHDQLAAVQAQMRKAMARG---SEGESSSSRMLPTFVRATLTGSERGDFL 182
Query: 325 ALDLGGTNFRVLIINLGENHFDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVY 504
ALDLGGTNFRVL++ + + S+IY+IP+ + G+ LFDHI +C+ +F ++ G+
Sbjct: 183 ALDLGGTNFRVLLVRVTTG-VQITSEIYSIPETVAQGSAEQLFDHIVDCIVDFQQKQGLS 241
Query: 505 EERLALGFTFSFPLKQLGLTKGVLQRWTKGFSCSGVVGEDVVQGLKDAIARRGDVQIDIC 684
+ L GFTFSFP +QLGL +G+L WTKGF S G+DVV L++AI RR V++++
Sbjct: 242 GQSLPTGFTFSFPCRQLGLDQGILLNWTKGFKASDCEGQDVVSLLREAITRRQAVELNVV 301
Query: 685 AILNDTTGTLMSCAWKNHNCXI 750
AI+NDT GT+MSC +++ C I
Sbjct: 302 AIVNDTVGTMMSCGYEDPRCEI 323
>AL596223-5|CAH71502.1| 139|Homo sapiens hexokinase 1 protein.
Length = 139
Score = 98.3 bits (234), Expect = 3e-20
Identities = 43/106 (40%), Positives = 74/106 (69%), Gaps = 3/106 (2%)
Frame = +1
Query: 166 LKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKERGKFLALDLGGT 345
++++D+ + +IM R ++K GLSR + ATVK T+++ +P+G E+G F+ALDLGG+
Sbjct: 33 MRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFIALDLGGS 92
Query: 346 NFRVLIINLG---ENHFDMQSKIYAIPKHIMTGTGIALFDHIAECL 474
+FR+L + + + M+S++Y P++I+ G+G LFDH+AECL
Sbjct: 93 SFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECL 138
>AL596223-7|CAH71504.1| 114|Homo sapiens hexokinase 1 protein.
Length = 114
Score = 80.2 bits (189), Expect = 7e-15
Identities = 36/98 (36%), Positives = 66/98 (67%), Gaps = 3/98 (3%)
Frame = +1
Query: 166 LKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKERGKFLALDLGGT 345
++++D+ + +IM R ++K GLSR + ATVK T+++ +P+G E+G F+ALDLGG+
Sbjct: 17 MRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFIALDLGGS 76
Query: 346 NFRVLIINLG---ENHFDMQSKIYAIPKHIMTGTGIAL 450
+FR+L + + + M+S++Y P++I+ G+G L
Sbjct: 77 SFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQL 114
>AF073786-1|AAC25424.1| 114|Homo sapiens testis-specific hexokinase
1 protein.
Length = 114
Score = 80.2 bits (189), Expect = 7e-15
Identities = 36/98 (36%), Positives = 66/98 (67%), Gaps = 3/98 (3%)
Frame = +1
Query: 166 LKMTDKQIKEIMCRLHNDLKKGLSRADHDKATVKCWITYIQDLPNGKERGKFLALDLGGT 345
++++D+ + +IM R ++K GLSR + ATVK T+++ +P+G E+G F+ALDLGG+
Sbjct: 17 MRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFIALDLGGS 76
Query: 346 NFRVLIINLG---ENHFDMQSKIYAIPKHIMTGTGIAL 450
+FR+L + + + M+S++Y P++I+ G+G L
Sbjct: 77 SFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQL 114
>DQ871602-1|ABI49509.1| 127|Homo sapiens HK2 protein.
Length = 127
Score = 78.6 bits (185), Expect = 2e-14
Identities = 34/59 (57%), Positives = 42/59 (71%)
Frame = +1
Query: 574 LQRWTKGFSCSGVVGEDVVQGLKDAIARRGDVQIDICAILNDTTGTLMSCAWKNHNCXI 750
L WTKGF SGV G DVV ++ AI RRGD IDI A++NDT GT+M+C + +HNC I
Sbjct: 3 LVSWTKGFKSSGVEGRDVVALIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDHNCEI 61
>D25412-1|BAA04999.1| 126|Homo sapiens type 2 hexokinase protein.
Length = 126
Score = 72.1 bits (169), Expect = 2e-12
Identities = 29/60 (48%), Positives = 44/60 (73%)
Frame = +1
Query: 571 VLQRWTKGFSCSGVVGEDVVQGLKDAIARRGDVQIDICAILNDTTGTLMSCAWKNHNCXI 750
+L +WTKGF SG GEDVV LK+AI RR + +D+ A++NDT GT+M+C +++ +C +
Sbjct: 2 ILLKWTKGFKASGCEGEDVVTLLKEAIHRREEFDLDVVAVVNDTVGTMMTCGFEDPHCEV 61
>BX538078-1|CAD98002.1| 160|Homo sapiens hypothetical protein
protein.
Length = 160
Score = 37.9 bits (84), Expect = 0.039
Identities = 13/26 (50%), Positives = 21/26 (80%)
Frame = +1
Query: 673 IDICAILNDTTGTLMSCAWKNHNCXI 750
+DI A++NDT GT+M+C +++ NC I
Sbjct: 2 LDIVAVVNDTVGTMMTCGYEDPNCEI 27
>BC121179-1|AAI21180.1| 722|Homo sapiens glucosamine
(UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
protein.
Length = 722
Score = 30.3 bits (65), Expect = 7.7
Identities = 14/29 (48%), Positives = 20/29 (68%)
Frame = +1
Query: 286 QDLPNGKERGKFLALDLGGTNFRVLIINL 372
QD+ + E LA+DLGGTN RV I+++
Sbjct: 398 QDIDHILETLSALAVDLGGTNLRVAIVSM 426
>AY531128-1|AAS59259.1| 722|Homo sapiens
UDP-N-acetylglucosamine-2-epimerase /
N-acetylmannosamine kinase protein.
Length = 722
Score = 30.3 bits (65), Expect = 7.7
Identities = 14/29 (48%), Positives = 20/29 (68%)
Frame = +1
Query: 286 QDLPNGKERGKFLALDLGGTNFRVLIINL 372
QD+ + E LA+DLGGTN RV I+++
Sbjct: 398 QDIDHILETLSALAVDLGGTNLRVAIVSM 426
>AY531127-1|AAS59258.1| 722|Homo sapiens
UDP-N-acetylglucosamine-2-epimerase /
N-acetylmannosamine kinase protein.
Length = 722
Score = 30.3 bits (65), Expect = 7.7
Identities = 14/29 (48%), Positives = 20/29 (68%)
Frame = +1
Query: 286 QDLPNGKERGKFLALDLGGTNFRVLIINL 372
QD+ + E LA+DLGGTN RV I+++
Sbjct: 398 QDIDHILETLSALAVDLGGTNLRVAIVSM 426
>AY531126-1|AAS59257.1| 722|Homo sapiens
UDP-N-acetylglucosamine-2-epimerase /
N-acetylmannosamine kinase protein.
Length = 722
Score = 30.3 bits (65), Expect = 7.7
Identities = 14/29 (48%), Positives = 20/29 (68%)
Frame = +1
Query: 286 QDLPNGKERGKFLALDLGGTNFRVLIINL 372
QD+ + E LA+DLGGTN RV I+++
Sbjct: 398 QDIDHILETLSALAVDLGGTNLRVAIVSM 426
>AM697709-1|CAM91425.1| 681|Homo sapiens UDP-N-acetylglucosamine
2-epimerase/N-acetylmannosamine kinase protein.
Length = 681
Score = 30.3 bits (65), Expect = 7.7
Identities = 14/29 (48%), Positives = 20/29 (68%)
Frame = +1
Query: 286 QDLPNGKERGKFLALDLGGTNFRVLIINL 372
QD+ + E LA+DLGGTN RV I+++
Sbjct: 357 QDIDHILETLSALAVDLGGTNLRVAIVSM 385
>AM697708-1|CAM91424.1| 753|Homo sapiens UDP-N-acetylglucosamine
2-epimerase/N-acetylmannosamine kinase protein.
Length = 753
Score = 30.3 bits (65), Expect = 7.7
Identities = 14/29 (48%), Positives = 20/29 (68%)
Frame = +1
Query: 286 QDLPNGKERGKFLALDLGGTNFRVLIINL 372
QD+ + E LA+DLGGTN RV I+++
Sbjct: 429 QDIDHILETLSALAVDLGGTNLRVAIVSM 457
>AL158830-7|CAD13389.1| 722|Homo sapiens glucosamine
(UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
protein.
Length = 722
Score = 30.3 bits (65), Expect = 7.7
Identities = 14/29 (48%), Positives = 20/29 (68%)
Frame = +1
Query: 286 QDLPNGKERGKFLALDLGGTNFRVLIINL 372
QD+ + E LA+DLGGTN RV I+++
Sbjct: 398 QDIDHILETLSALAVDLGGTNLRVAIVSM 426
>AJ238764-1|CAB42607.1| 722|Homo sapiens
UDP-N-acetylglucosamine-2-epimerase /
N-acetylmannosamine kinase protein.
Length = 722
Score = 30.3 bits (65), Expect = 7.7
Identities = 14/29 (48%), Positives = 20/29 (68%)
Frame = +1
Query: 286 QDLPNGKERGKFLALDLGGTNFRVLIINL 372
QD+ + E LA+DLGGTN RV I+++
Sbjct: 398 QDIDHILETLSALAVDLGGTNLRVAIVSM 426
>AF317635-1|AAG31661.1| 722|Homo sapiens UDP-N-acetylglucosamine
2-epimerase protein.
Length = 722
Score = 30.3 bits (65), Expect = 7.7
Identities = 14/29 (48%), Positives = 20/29 (68%)
Frame = +1
Query: 286 QDLPNGKERGKFLALDLGGTNFRVLIINL 372
QD+ + E LA+DLGGTN RV I+++
Sbjct: 398 QDIDHILETLSALAVDLGGTNLRVAIVSM 426
>AF155663-1|AAD38197.1| 722|Homo sapiens
UDP-N-acetylglucosamine-2-epimerase/N- acetylmannosamine
kinase protein.
Length = 722
Score = 30.3 bits (65), Expect = 7.7
Identities = 14/29 (48%), Positives = 20/29 (68%)
Frame = +1
Query: 286 QDLPNGKERGKFLALDLGGTNFRVLIINL 372
QD+ + E LA+DLGGTN RV I+++
Sbjct: 398 QDIDHILETLSALAVDLGGTNLRVAIVSM 426
>AF051852-1|AAD32251.1| 722|Homo sapiens
UDP-N-acetylglucosamine-2-epimerase protein.
Length = 722
Score = 30.3 bits (65), Expect = 7.7
Identities = 14/29 (48%), Positives = 20/29 (68%)
Frame = +1
Query: 286 QDLPNGKERGKFLALDLGGTNFRVLIINL 372
QD+ + E LA+DLGGTN RV I+++
Sbjct: 398 QDIDHILETLSALAVDLGGTNLRVAIVSM 426
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 109,439,273
Number of Sequences: 237096
Number of extensions: 2354957
Number of successful extensions: 4628
Number of sequences better than 10.0: 54
Number of HSP's better than 10.0 without gapping: 4299
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4560
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 9015132854
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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