Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P03_F_I22
(831 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC029118-1|AAH29118.1| 371|Homo sapiens leucine rich repeat con... 106 9e-23
AK223440-1|BAD97160.1| 371|Homo sapiens leucine rich repeat con... 106 9e-23
AK057808-1|BAB71585.1| 371|Homo sapiens protein ( Homo sapiens ... 106 9e-23
AJ308569-1|CAC33442.1| 371|Homo sapiens leucine-rich repeat-con... 106 1e-22
BC115015-1|AAI15016.1| 1367|Homo sapiens ERBB2IP protein protein. 98 3e-20
BC115012-1|AAI15013.1| 1371|Homo sapiens erbb2 interacting prote... 98 3e-20
BC050692-1|AAH50692.1| 633|Homo sapiens ERBB2IP protein protein. 98 3e-20
AF276423-1|AAK69431.1| 1412|Homo sapiens densin-180-like protein... 98 3e-20
AF263744-1|AAF77048.1| 1371|Homo sapiens erbb2-interacting prote... 98 3e-20
AB033051-1|BAA86539.2| 1371|Homo sapiens KIAA1225 protein protein. 98 3e-20
BC126464-1|AAI26465.1| 1371|Homo sapiens erbb2 interacting prote... 97 9e-20
BC050445-1|AAH50445.1| 582|Homo sapiens soc-2 suppressor of cle... 95 2e-19
AL158163-2|CAH72812.1| 582|Homo sapiens soc-2 suppressor of cle... 95 2e-19
AF068920-1|AAC39856.1| 582|Homo sapiens Ras-binding protein SUR... 95 2e-19
AF054828-1|AAC25698.1| 582|Homo sapiens leucine-rich repeat pro... 95 2e-19
AB020669-1|BAA74885.2| 584|Homo sapiens KIAA0862 protein protein. 95 2e-19
AL391728-2|CAH73692.1| 1495|Homo sapiens leucine rich repeat con... 95 4e-19
AL391728-1|CAH73691.1| 1537|Homo sapiens leucine rich repeat con... 95 4e-19
AL359412-2|CAH74019.1| 1495|Homo sapiens leucine rich repeat con... 95 4e-19
AL359412-1|CAH74018.1| 1537|Homo sapiens leucine rich repeat con... 95 4e-19
AL158840-2|CAH70975.1| 1495|Homo sapiens leucine rich repeat con... 95 4e-19
AL158840-1|CAH70974.1| 1537|Homo sapiens leucine rich repeat con... 95 4e-19
AL157948-2|CAI22426.1| 1495|Homo sapiens leucine rich repeat con... 95 4e-19
AL157948-1|CAI22425.1| 1537|Homo sapiens leucine rich repeat con... 95 4e-19
AL117353-1|CAI23423.1| 1495|Homo sapiens leucine rich repeat con... 95 4e-19
AF434715-1|AAL28133.1| 1537|Homo sapiens densin-180 protein. 95 4e-19
BC014904-1|AAH14904.1| 893|Homo sapiens leucine-rich repeats an... 94 6e-19
AF274972-1|AAG13461.1| 910|Homo sapiens PIDD protein. 94 6e-19
BC003193-1|AAH03193.1| 524|Homo sapiens leucine rich repeat con... 89 2e-17
AL513211-1|CAI17358.1| 524|Homo sapiens leucine rich repeat con... 89 2e-17
AL033384-1|CAI21666.1| 524|Homo sapiens leucine rich repeat con... 89 2e-17
AF359380-1|AAK72246.1| 524|Homo sapiens LANO adaptor protein pr... 89 2e-17
AF332199-1|AAK69623.1| 524|Homo sapiens leucine-rich repeats pr... 89 2e-17
BC058935-1|AAH58935.1| 239|Homo sapiens LRRC57 protein protein. 86 1e-16
AK094891-1|BAC04451.1| 239|Homo sapiens protein ( Homo sapiens ... 86 1e-16
AK094131-1|BAC04294.1| 239|Homo sapiens (EC 2.4.1.101). protein. 86 1e-16
D63481-1|BAA09768.3| 1630|Homo sapiens KIAA0147 protein protein. 84 5e-16
BC008586-1|AAH08586.1| 602|Homo sapiens leucine rich repeat con... 84 5e-16
BC003407-1|AAH03407.2| 581|Homo sapiens LRRC40 protein protein. 84 5e-16
AY062238-1|AAL38976.1| 1630|Homo sapiens scribble protein. 84 5e-16
AL353771-3|CAI22332.1| 602|Homo sapiens leucine rich repeat con... 84 5e-16
AK022951-1|BAB14326.1| 602|Homo sapiens protein ( Homo sapiens ... 84 5e-16
AF271734-1|AAP88018.1| 1601|Homo sapiens SCRIB1 variant N1 protein. 84 5e-16
AF240677-1|AAP88017.1| 1630|Homo sapiens CRIB1 protein. 84 5e-16
BC009613-1|AAH09613.1| 335|Homo sapiens leucine rich repeat con... 83 1e-15
AY358131-1|AAQ88498.1| 335|Homo sapiens densin hlg protein. 83 1e-15
AL445928-6|CAH72254.1| 339|Homo sapiens leucine rich repeat con... 83 1e-15
AL445928-5|CAH72253.1| 335|Homo sapiens leucine rich repeat con... 83 1e-15
AL158163-3|CAH72813.1| 372|Homo sapiens soc-2 suppressor of cle... 81 4e-15
AF229178-1|AAF69491.1| 753|Homo sapiens leucine rich repeat and... 80 8e-15
BC125224-1|AAI25225.1| 748|Homo sapiens LRCH2 protein protein. 79 1e-14
BC018529-1|AAH18529.3| 683|Homo sapiens leucine-rich repeats an... 79 1e-14
BC007634-1|AAH07634.1| 580|Homo sapiens LRCH4 protein protein. 79 1e-14
AF053356-12|AAC78793.1| 832|Homo sapiens leucin rich neuronal p... 79 1e-14
BC047306-1|AAH47306.1| 367|Homo sapiens leucine rich repeat con... 79 3e-14
AY358082-1|AAQ88449.1| 312|Homo sapiens ASEL436 protein. 79 3e-14
BC106893-1|AAI06894.1| 250|Homo sapiens LRRC10 protein protein. 76 1e-13
BC106892-1|AAI06893.1| 249|Homo sapiens LRRC10 protein protein. 76 1e-13
BC090881-1|AAH90881.1| 277|Homo sapiens leucine rich repeat con... 76 1e-13
AK123908-1|BAC85724.1| 250|Homo sapiens protein ( Homo sapiens ... 76 1e-13
AB016816-1|BAA74737.1| 1052|Homo sapiens MASL1 protein. 76 1e-13
AK001637-1|BAA91801.1| 183|Homo sapiens protein ( Homo sapiens ... 75 3e-13
BC051322-1|AAH51322.1| 810|Homo sapiens leucine rich repeat con... 75 4e-13
AY358286-1|AAQ88653.1| 546|Homo sapiens RQTI221 protein. 75 4e-13
AY143166-1|AAN18279.1| 810|Homo sapiens leucine-rich repeat-con... 75 4e-13
AL672142-1|CAI10839.1| 810|Homo sapiens leucine rich repeat con... 75 4e-13
AK027495-1|BAB55153.1| 474|Homo sapiens protein ( Homo sapiens ... 75 4e-13
AK001199-1|BAA91549.1| 221|Homo sapiens protein ( Homo sapiens ... 75 4e-13
AB037858-1|BAA92675.1| 811|Homo sapiens KIAA1437 protein protein. 75 4e-13
AK074723-1|BAC11161.1| 546|Homo sapiens protein ( Homo sapiens ... 74 7e-13
BC024159-1|AAH24159.2| 858|Homo sapiens leucine rich repeat con... 73 2e-12
AY358874-1|AAQ89233.1| 501|Homo sapiens LRRC5 protein. 73 2e-12
AL391497-3|CAH72226.1| 858|Homo sapiens leucine rich repeat con... 73 2e-12
AK222787-1|BAD96507.1| 671|Homo sapiens leucine rich repeat con... 73 2e-12
AK001332-1|BAA91631.1| 682|Homo sapiens protein ( Homo sapiens ... 73 2e-12
BC108252-1|AAI08253.1| 532|Homo sapiens LRRC8E protein protein. 72 2e-12
BC070089-1|AAH70089.1| 796|Homo sapiens leucine rich repeat con... 72 2e-12
BC022216-1|AAH22216.2| 592|Homo sapiens LRRC8E protein protein. 72 2e-12
AY358137-1|AAQ88504.1| 255|Homo sapiens VKGE9338 protein. 72 2e-12
AL834474-1|CAD39133.1| 622|Homo sapiens hypothetical protein pr... 72 2e-12
AK027073-1|BAB15648.1| 444|Homo sapiens protein ( Homo sapiens ... 72 2e-12
U80184-1|AAC02796.1| 1269|Homo sapiens FLII protein. 70 9e-12
U01184-1|AAC03568.1| 1268|Homo sapiens flightless-I homolog prot... 70 9e-12
BC025300-1|AAH25300.1| 1269|Homo sapiens flightless I homolog (D... 70 9e-12
AB208864-1|BAD92101.1| 1101|Homo sapiens flightless I homolog va... 70 9e-12
L12535-1|AAA60292.1| 277|Homo sapiens RSU-1 protein. 69 2e-11
CR541840-1|CAG46639.1| 277|Homo sapiens RSU1 protein. 69 2e-11
CR536521-1|CAG38758.1| 277|Homo sapiens RSU1 protein. 69 2e-11
BC015644-1|AAH15644.1| 277|Homo sapiens Ras suppressor protein ... 69 2e-11
BC008691-1|AAH08691.1| 277|Homo sapiens RSU1 protein protein. 69 2e-11
BC005993-1|AAH05993.1| 277|Homo sapiens Ras suppressor protein ... 69 2e-11
AL365215-3|CAH73633.1| 277|Homo sapiens Ras suppressor protein ... 69 2e-11
BC036722-1|AAH36722.1| 261|Homo sapiens leucine rich repeat con... 69 2e-11
BC107898-1|AAI07899.1| 280|Homo sapiens RSU1 protein protein. 66 1e-10
BC129927-1|AAI29928.1| 1323|Homo sapiens PH domain and leucine r... 66 1e-10
BC035267-1|AAH35267.1| 723|Homo sapiens PHLPPL protein protein. 66 1e-10
AB023148-1|BAA76775.2| 1258|Homo sapiens KIAA0931 protein protein. 66 1e-10
AK021896-1|BAB13929.1| 197|Homo sapiens protein ( Homo sapiens ... 64 4e-10
AK000338-1|BAA91094.1| 384|Homo sapiens protein ( Homo sapiens ... 64 4e-10
BC113973-1|AAI13974.1| 803|Homo sapiens factor for adipocyte di... 64 6e-10
AB081509-1|BAB86303.1| 803|Homo sapiens AD158 protein. 64 6e-10
BC013757-1|AAH13757.1| 403|Homo sapiens LRRC58 protein protein. 63 1e-09
BC009239-1|AAH09239.1| 723|Homo sapiens leucine rich repeat and... 63 1e-09
AY358830-1|AAQ89189.1| 723|Homo sapiens leucine-rich protein pr... 63 1e-09
AL445222-17|CAH72931.1| 696|Homo sapiens leucine rich repeat an... 63 1e-09
AL445222-16|CAH72930.1| 723|Homo sapiens leucine rich repeat an... 63 1e-09
AL365215-2|CAH73632.1| 224|Homo sapiens Ras suppressor protein ... 63 1e-09
AK091589-1|BAC03703.1| 723|Homo sapiens protein ( Homo sapiens ... 63 1e-09
AK056203-1|BAB71119.1| 696|Homo sapiens protein ( Homo sapiens ... 63 1e-09
AL589786-1|CAH70721.1| 612|Homo sapiens leucine-rich repeats an... 62 2e-09
AL445164-1|CAI43033.1| 612|Homo sapiens leucine-rich repeats an... 62 2e-09
AL121878-2|CAI42077.1| 612|Homo sapiens leucine-rich repeats an... 62 2e-09
D86984-1|BAA13220.2| 823|Homo sapiens KIAA0231 protein protein. 62 2e-09
BC060782-1|AAH60782.1| 803|Homo sapiens LRRC8B protein protein. 62 2e-09
BC030607-1|AAH30607.1| 803|Homo sapiens leucine rich repeat con... 62 2e-09
AY358112-1|AAQ88479.1| 802|Homo sapiens ITLT6413 protein. 62 2e-09
AF385436-1|AAM43837.1| 803|Homo sapiens T-cell activation leuci... 62 2e-09
BC099650-1|AAH99650.1| 907|Homo sapiens leucine-rich repeat-con... 61 4e-09
BC096324-1|AAH96324.1| 907|Homo sapiens leucine-rich repeat-con... 61 4e-09
AF062006-1|AAC28019.1| 907|Homo sapiens orphan G protein-couple... 61 4e-09
BC007504-1|AAH07504.1| 712|Homo sapiens leucine-rich repeats an... 60 7e-09
AK124678-1|BAC85924.1| 423|Homo sapiens protein ( Homo sapiens ... 60 1e-08
BC030276-1|AAH30276.1| 529|Homo sapiens LOC220416 protein protein. 59 2e-08
AL139801-5|CAM14704.1| 506|Homo sapiens similar to Leucine-rich... 59 2e-08
AL137141-1|CAI12166.2| 506|Homo sapiens similar to Leucine-rich... 59 2e-08
BC101065-1|AAI01066.1| 581|Homo sapiens LRRC15 protein protein. 59 2e-08
BC101064-1|AAI01065.1| 581|Homo sapiens leucine rich repeat con... 59 2e-08
AF061444-1|AAC77911.1| 907|Homo sapiens G protein-coupled recep... 59 2e-08
BC052279-1|AAH52279.1| 307|Homo sapiens leucine rich repeat con... 58 5e-08
BC017168-1|AAH17168.1| 307|Homo sapiens leucine rich repeat con... 58 5e-08
BC024001-1|AAH24001.1| 184|Homo sapiens leucine rich repeat con... 57 7e-08
AY358318-1|AAQ88684.1| 184|Homo sapiens LKKM2429 protein. 57 7e-08
AL513211-2|CAI17359.1| 154|Homo sapiens leucine rich repeat con... 57 7e-08
AL355138-5|CAI12602.1| 175|Homo sapiens leucine rich repeat con... 57 7e-08
AL355138-3|CAI12600.1| 184|Homo sapiens leucine rich repeat con... 57 7e-08
AK094734-1|BAC04409.1| 184|Homo sapiens protein ( Homo sapiens ... 57 7e-08
AB071037-1|BAB84587.1| 581|Homo sapiens Lib protein. 57 9e-08
BC032667-1|AAH32667.1| 352|Homo sapiens keratocan protein. 56 1e-07
AF205403-1|AAF69126.1| 352|Homo sapiens keratocan protein. 56 1e-07
AF065988-1|AAC17741.1| 352|Homo sapiens keratocan protein. 56 1e-07
AF063301-1|AAC16390.1| 352|Homo sapiens keratan sulfate proteog... 56 1e-07
AL022344-3|CAI23616.1| 146|Homo sapiens novel protein similar t... 56 2e-07
BC126277-1|AAI26278.1| 1205|Homo sapiens PH domain and leucine r... 54 5e-07
BC103509-1|AAI03510.1| 958|Homo sapiens SLIT and NTRK-like fami... 54 5e-07
BC098287-1|AAH98287.1| 958|Homo sapiens SLIT and NTRK-like fami... 54 5e-07
BC098106-1|AAH98106.1| 958|Homo sapiens SLIT and NTRK-like fami... 54 5e-07
BC014927-1|AAH14927.3| 1205|Homo sapiens PH domain and leucine r... 54 5e-07
AL603883-1|CAH73026.1| 958|Homo sapiens SLIT and NTRK-like fami... 54 5e-07
AK001924-1|BAA91980.1| 721|Homo sapiens protein ( Homo sapiens ... 54 5e-07
AB020725-1|BAA74941.1| 966|Homo sapiens KIAA0918 protein protein. 54 5e-07
AB011178-1|BAA25532.2| 1369|Homo sapiens KIAA0606 protein protein. 54 5e-07
BC117472-1|AAI17473.1| 763|Homo sapiens LRCH1 protein protein. 54 6e-07
BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2 (Drosoph... 54 6e-07
BC112937-1|AAI12938.1| 696|Homo sapiens LRCH1 protein protein. 54 6e-07
BC033039-1|AAH33039.1| 927|Homo sapiens LGR4 protein protein. 54 6e-07
AY050632-1|AAK95568.1| 728|Homo sapiens neuronal protein isofor... 54 6e-07
AY050631-1|AAK95567.1| 696|Homo sapiens neuronal protein isofor... 54 6e-07
AL359880-1|CAH70792.1| 734|Homo sapiens leucine-rich repeats an... 54 6e-07
AL138704-1|CAH73642.1| 734|Homo sapiens leucine-rich repeats an... 54 6e-07
AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein. 54 6e-07
AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellula... 54 6e-07
AB033020-1|BAA86508.1| 575|Homo sapiens KIAA1194 protein protein. 54 6e-07
AB023233-1|BAA76860.1| 793|Homo sapiens KIAA1016 protein protein. 54 6e-07
AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein. 54 6e-07
BC146759-1|AAI46760.1| 1523|Homo sapiens slit homolog 3 (Drosoph... 54 8e-07
AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein. 54 8e-07
AF075240-1|AAD19336.1| 850|Homo sapiens SLIT1 protein protein. 54 8e-07
AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein. 54 8e-07
AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein. 54 8e-07
BC095477-1|AAH95477.1| 522|Homo sapiens AMIGO2 protein protein. 52 2e-06
BC047595-1|AAH47595.1| 522|Homo sapiens adhesion molecule with ... 52 2e-06
AY454159-1|AAR83271.1| 522|Homo sapiens DEGA/AMIGO-2 precursor ... 52 2e-06
AY237005-1|AAO48946.1| 522|Homo sapiens transmembrane protein A... 52 2e-06
AB080610-1|BAC81189.1| 522|Homo sapiens alivin 1 protein. 52 2e-06
U41344-1|AAC18782.1| 382|Homo sapiens prolargin protein. 52 3e-06
U29089-1|AAC50230.1| 382|Homo sapiens proline- arginine-rich en... 52 3e-06
CR542270-1|CAG47066.1| 382|Homo sapiens PRELP protein. 52 3e-06
CR541787-1|CAG46586.1| 382|Homo sapiens PRELP protein. 52 3e-06
BC032498-1|AAH32498.1| 382|Homo sapiens proline/arginine-rich e... 52 3e-06
AL391817-1|CAI17033.1| 382|Homo sapiens proline/arginine-rich e... 52 3e-06
AK127177-1|BAC86870.1| 279|Homo sapiens protein ( Homo sapiens ... 52 3e-06
BC051738-1|AAH51738.1| 696|Homo sapiens SLIT and NTRK-like fami... 51 6e-06
AY358289-1|AAQ88656.1| 696|Homo sapiens LLWI233 protein. 51 6e-06
AL355481-1|CAC37488.1| 696|Homo sapiens SLIT and NTRK-like fami... 51 6e-06
AL159161-1|CAI17102.1| 754|Homo sapiens relaxin/insulin-like fa... 51 6e-06
AL138708-1|CAH73785.1| 754|Homo sapiens relaxin/insulin-like fa... 51 6e-06
AF453828-1|AAL73946.1| 754|Homo sapiens G protein-coupled recep... 51 6e-06
AF403384-1|AAL69324.2| 754|Homo sapiens LGR8 protein. 51 6e-06
AB067497-1|BAB67803.1| 760|Homo sapiens KIAA1910 protein protein. 51 6e-06
Y19205-1|CAC80724.1| 845|Homo sapiens SLITL1 protein. 50 8e-06
U96769-1|AAC13410.1| 359|Homo sapiens chondroadherin protein. 50 8e-06
BC113012-1|AAI13013.1| 845|Homo sapiens SLIT and NTRK-like fami... 50 8e-06
BC113011-1|AAI13012.1| 845|Homo sapiens SLIT and NTRK-like fami... 50 8e-06
BC073974-1|AAH73974.1| 359|Homo sapiens chondroadherin protein. 50 8e-06
BC036360-1|AAH36360.1| 359|Homo sapiens chondroadherin protein. 50 8e-06
AY358828-1|AAQ89187.1| 733|Homo sapiens LSGV9197 protein. 50 8e-06
AL109653-2|CAC18888.1| 845|Homo sapiens SLIT and NTRK-like fami... 50 8e-06
AL109653-1|CAI41645.1| 724|Homo sapiens SLIT and NTRK-like fami... 50 8e-06
AK091015-1|BAC03566.1| 724|Homo sapiens protein ( Homo sapiens ... 50 8e-06
AF371328-1|AAK51556.1| 359|Homo sapiens chondroadherin protein. 50 8e-06
AB058757-1|BAB47483.1| 572|Homo sapiens KIAA1854 protein protein. 50 8e-06
AL391728-3|CAH73693.1| 217|Homo sapiens leucine rich repeat con... 50 1e-05
AL359894-1|CAH73131.1| 217|Homo sapiens leucine rich repeat con... 50 1e-05
AL359412-3|CAH74020.1| 217|Homo sapiens leucine rich repeat con... 50 1e-05
AL117353-2|CAI23424.1| 217|Homo sapiens leucine rich repeat con... 50 1e-05
AF498274-1|AAP06801.1| 217|Homo sapiens densin-180 like protein... 50 1e-05
BC040986-1|AAH40986.1| 837|Homo sapiens SLIT and NTRK-like fami... 50 1e-05
AL713693-1|CAD28493.1| 689|Homo sapiens hypothetical protein pr... 50 1e-05
AL080239-3|CAI41650.1| 837|Homo sapiens novel protein protein. 50 1e-05
AK057619-1|BAB71535.1| 469|Homo sapiens protein ( Homo sapiens ... 50 1e-05
BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats an... 49 2e-05
BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats an... 49 2e-05
AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and immuno... 49 2e-05
AY358733-1|AAQ89095.1| 622|Homo sapiens CGLQ1891 protein. 49 2e-05
AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein. 49 2e-05
AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein. 49 2e-05
AY280614-1|AAP36706.1| 622|Homo sapiens synleurin protein. 49 2e-05
AK123022-1|BAC85517.1| 622|Homo sapiens protein ( Homo sapiens ... 49 2e-05
AB209743-1|BAD92980.1| 1032|Homo sapiens Leucine-rich repeat-con... 49 2e-05
BC101073-1|AAI01074.1| 841|Homo sapiens SLIT and NTRK-like fami... 49 2e-05
BC101072-1|AAI01073.1| 841|Homo sapiens SLIT and NTRK-like fami... 49 2e-05
BC101071-1|AAI01072.1| 841|Homo sapiens SLIT and NTRK-like fami... 49 2e-05
BC101070-1|AAI01071.1| 841|Homo sapiens SLIT and NTRK-like fami... 49 2e-05
AK026427-1|BAB15480.1| 440|Homo sapiens protein ( Homo sapiens ... 48 3e-05
AF346711-1|AAK31153.1| 951|Homo sapiens G-protein couple recept... 48 3e-05
AF257182-1|AAF68989.1| 951|Homo sapiens G-protein-coupled recep... 48 3e-05
BC082244-1|AAH82244.1| 465|Homo sapiens PHLPP protein protein. 48 4e-05
BC031301-1|AAH31301.1| 583|Homo sapiens leucine rich repeat con... 48 4e-05
AL365330-3|CAI42528.1| 583|Homo sapiens leucine rich repeat con... 48 4e-05
Z23091-1|CAA80637.1| 560|Homo sapiens platelet glycoprotein V p... 47 7e-05
L11238-1|AAA03069.1| 560|Homo sapiens platelet membrane glycopr... 47 7e-05
BC070198-1|AAH70198.1| 347|Homo sapiens leucine-rich alpha-2-gl... 47 1e-04
BC034389-1|AAH34389.1| 347|Homo sapiens leucine-rich alpha-2-gl... 47 1e-04
BC018370-1|AAH18370.1| 674|Homo sapiens fibronectin leucine ric... 47 1e-04
AY358308-1|AAQ88675.1| 674|Homo sapiens FLRT1 protein. 47 1e-04
AF403428-1|AAK95527.1| 347|Homo sapiens leucine-rich alpha-2-gl... 47 1e-04
AF169675-1|AAF28459.1| 674|Homo sapiens leucine-rich repeat tra... 47 1e-04
AB073607-1|BAD38644.1| 347|Homo sapiens leucine-rich alpha-2-gl... 47 1e-04
BC096326-1|AAH96326.1| 883|Homo sapiens LGR5 protein protein. 46 2e-04
BC096325-1|AAH96325.1| 883|Homo sapiens LGR5 protein protein. 46 2e-04
BC057786-1|AAH57786.1| 512|Homo sapiens podocan-like 1 protein. 46 2e-04
AK058188-1|BAB71707.1| 475|Homo sapiens protein ( Homo sapiens ... 46 2e-04
BC117180-1|AAI17181.1| 2527|Homo sapiens leucine-rich repeat kin... 45 3e-04
AY792511-1|AAV63975.1| 2527|Homo sapiens leucine-rich repeat kin... 45 3e-04
AY730707-1|AAU44786.1| 1093|Homo sapiens leucine-rich repeat pro... 45 3e-04
AK127729-1|BAC87105.1| 870|Homo sapiens protein ( Homo sapiens ... 45 3e-04
BC030608-1|AAH30608.1| 661|Homo sapiens podocan protein. 45 4e-04
AY358294-1|AAQ88661.1| 642|Homo sapiens EGEE293 protein. 45 4e-04
AY313607-1|AAP79898.1| 613|Homo sapiens podocan protein protein. 45 4e-04
AL445183-5|CAH72592.1| 642|Homo sapiens podocan protein. 45 4e-04
AL445183-4|CAH72591.1| 661|Homo sapiens podocan protein. 45 4e-04
BC089415-1|AAH89415.1| 446|Homo sapiens CEP110 protein protein. 44 5e-04
BC068575-1|AAH68575.1| 673|Homo sapiens vasorin protein. 44 5e-04
BC063114-1|AAH63114.1| 384|Homo sapiens ASPN protein protein. 44 5e-04
BC013767-1|AAH13767.1| 601|Homo sapiens VASN protein protein. 44 5e-04
AY358329-1|AAQ88695.1| 379|Homo sapiens ASPN protein. 44 5e-04
AY358299-1|AAQ88666.1| 673|Homo sapiens CSRV314 protein. 44 5e-04
AY166584-1|AAO27704.1| 673|Homo sapiens vasorin protein. 44 5e-04
AY029191-1|AAK31800.1| 381|Homo sapiens periodontal ligament as... 44 5e-04
AL137848-6|CAI16697.1| 380|Homo sapiens asporin protein. 44 5e-04
AL137848-5|CAI16698.1| 243|Homo sapiens asporin protein. 44 5e-04
AL137068-2|CAM13285.1| 2325|Homo sapiens centrosomal protein 110... 44 5e-04
AL137068-1|CAI12355.1| 452|Homo sapiens centrosomal protein 110... 44 5e-04
AK223302-1|BAD97022.1| 368|Homo sapiens biglycan preproprotein ... 44 5e-04
AK027359-1|BAB55060.1| 246|Homo sapiens protein ( Homo sapiens ... 44 5e-04
AK001706-1|BAA91849.1| 184|Homo sapiens protein ( Homo sapiens ... 44 5e-04
AF513978-1|AAP43846.1| 2325|Homo sapiens CENTRIOLIN protein. 44 5e-04
AF316824-1|AAK35161.1| 379|Homo sapiens asporin precursor protein. 44 5e-04
M86826-1|AAA36047.1| 605|Homo sapiens insulin-like growth facto... 44 7e-04
BC026112-1|AAH26112.1| 116|Homo sapiens hypothetical protein LO... 44 7e-04
BC025681-1|AAH25681.1| 605|Homo sapiens insulin-like growth fac... 44 7e-04
AL031724-2|CAC36078.1| 605|Homo sapiens C447E6.2 (insulin-like ... 44 7e-04
AF192554-1|AAF06774.1| 605|Homo sapiens acid-labile subunit pro... 44 7e-04
AL355138-4|CAI12601.1| 134|Homo sapiens leucine rich repeat con... 44 9e-04
BC114621-1|AAI14622.1| 977|Homo sapiens SLIT and NTRK-like fami... 43 0.001
BC033651-1|AAH33651.1| 1049|Homo sapiens toll-like receptor 7 pr... 43 0.001
AY358292-1|AAQ88659.1| 1049|Homo sapiens TLR7 protein. 43 0.001
AF240467-1|AAF60188.1| 1049|Homo sapiens toll-like receptor 7 pr... 43 0.001
AB020655-1|BAA74871.2| 988|Homo sapiens KIAA0848 protein protein. 43 0.001
J04599-1|AAA36009.1| 368|Homo sapiens protein ( Human hPGI mRNA... 43 0.002
BT007323-1|AAP35987.1| 368|Homo sapiens biglycan protein. 43 0.002
BC126410-1|AAI26411.1| 516|Homo sapiens leucine rich repeat tra... 43 0.002
BC126408-1|AAI26409.1| 516|Homo sapiens leucine rich repeat tra... 43 0.002
BC004244-1|AAH04244.1| 368|Homo sapiens biglycan protein. 43 0.002
BC002416-1|AAH02416.1| 368|Homo sapiens biglycan protein. 43 0.002
AY182026-1|AAO67547.1| 516|Homo sapiens leucine-rich repeat tra... 43 0.002
AK222484-1|BAD96204.1| 368|Homo sapiens biglycan preproprotein ... 43 0.002
AB007876-1|BAA24846.2| 529|Homo sapiens KIAA0416 protein. 43 0.002
D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein. 42 0.002
BC139921-1|AAI39922.1| 414|Homo sapiens peptidylprolyl isomeras... 42 0.002
BC117370-1|AAI17371.1| 1065|Homo sapiens leucine-rich repeats an... 42 0.002
BC117368-1|AAI17369.1| 1065|Homo sapiens leucine-rich repeats an... 42 0.002
BC098579-1|AAH98579.1| 722|Homo sapiens PXDN protein protein. 42 0.002
BC056900-1|AAH56900.1| 1504|Homo sapiens nischarin protein. 42 0.002
BC054494-1|AAH54494.1| 1504|Homo sapiens nischarin protein. 42 0.002
BC038102-1|AAH38102.1| 1504|Homo sapiens nischarin protein. 42 0.002
AY358298-1|AAQ88665.1| 598|Homo sapiens CSRV314 protein. 42 0.002
AY052405-1|AAL11430.1| 414|Homo sapiens 4-1BB-mediated signalin... 42 0.002
AL357055-1|CAH73254.1| 1065|Homo sapiens leucine-rich repeats an... 42 0.002
AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated ant... 42 0.002
AF082516-1|AAC33104.1| 1504|Homo sapiens I-1 receptor candidate ... 42 0.002
AB023192-1|BAA76819.1| 1528|Homo sapiens KIAA0975 protein protein. 42 0.002
AB018349-1|BAA34526.2| 1073|Homo sapiens KIAA0806 protein protein. 42 0.002
DQ013130-1|AAY67799.1| 2014|Homo sapiens leucine-rich repeat kin... 42 0.003
BC046356-1|AAH46356.1| 421|Homo sapiens osteomodulin protein. 42 0.003
AY358872-1|AAQ89231.1| 421|Homo sapiens OMD protein. 42 0.003
AL137848-4|CAI16696.1| 421|Homo sapiens osteomodulin protein. 42 0.003
AB009589-1|BAA23982.1| 421|Homo sapiens Osteomodulin protein. 42 0.003
AB000114-1|BAA19055.1| 421|Homo sapiens osteomodulin protein. 42 0.003
X57436-1|CAA40684.1| 440|Homo sapiens oligodentrocyte-myelin gl... 42 0.004
X51694-1|CAA35991.1| 433|Homo sapiens oligodendrocyte-myelin gl... 42 0.004
M63623-1|AAA59970.1| 440|Homo sapiens oligodendrocyte-myelin gl... 42 0.004
BC018050-1|AAH18050.1| 440|Homo sapiens oligodendrocyte myelin ... 42 0.004
AK222663-1|BAD96383.1| 440|Homo sapiens oligodendrocyte myelin ... 42 0.004
M22403-1|AAA52596.1| 626|Homo sapiens platelet membrane glycopr... 41 0.005
J02940-1|AAA52595.1| 626|Homo sapiens GP1BA protein. 41 0.005
BC150572-1|AAI50573.1| 337|Homo sapiens LRRC55 protein protein. 41 0.005
BC027955-1|AAH27955.1| 626|Homo sapiens glycoprotein Ib (platel... 41 0.005
AM709890-1|CAM97225.1| 639|Homo sapiens platelet glycoprotein I... 41 0.005
AK127591-1|BAC87047.1| 341|Homo sapiens protein ( Homo sapiens ... 41 0.005
AF395009-1|AAK71325.1| 626|Homo sapiens glycoprotein Ib (platel... 41 0.005
AB086948-1|BAC10305.1| 626|Homo sapiens platelet glycoprotein I... 41 0.005
AB038516-1|BAB12038.1| 626|Homo sapiens platelet glycoprotein I... 41 0.005
BC146761-1|AAI46762.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 41 0.006
BC050665-1|AAH50665.1| 523|Homo sapiens LRRC48 protein protein. 41 0.006
BC050419-1|AAH50419.1| 523|Homo sapiens LRRC48 protein protein. 41 0.006
BC047873-1|AAH47873.1| 523|Homo sapiens leucine rich repeat con... 41 0.006
BC040276-1|AAH40276.1| 457|Homo sapiens LRRC48 protein protein. 41 0.006
BC030547-1|AAH30547.1| 647|Homo sapiens hypothetical protein DK... 41 0.006
AL512424-5|CAI14258.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 41 0.006
AL512424-4|CAI14259.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 41 0.006
AL442123-4|CAH70918.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 41 0.006
AL442123-3|CAH70917.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 41 0.006
AB017167-1|BAA35184.1| 1534|Homo sapiens Slit-1 protein protein. 41 0.006
AB011537-1|BAA32465.3| 1618|Homo sapiens MEGF4 protein. 41 0.006
M14219-1|AAB00774.1| 359|Homo sapiens proteoglycan core protein... 40 0.008
L01131-1|AAA52301.1| 347|Homo sapiens decorin protein. 40 0.008
CR541946-1|CAG46744.1| 359|Homo sapiens DCN protein. 40 0.008
CR407676-1|CAG28604.1| 359|Homo sapiens DCN protein. 40 0.008
BT019800-1|AAV38603.1| 359|Homo sapiens decorin protein. 40 0.008
BC042334-1|AAH42334.2| 545|Homo sapiens carboxypeptidase N, pol... 40 0.008
BC005322-1|AAH05322.1| 359|Homo sapiens decorin protein. 40 0.008
AK027100-1|BAB15657.1| 363|Homo sapiens protein ( Homo sapiens ... 40 0.008
AF491944-1|AAL92176.1| 359|Homo sapiens decorin protein. 40 0.008
AF138300-1|AAD44713.1| 359|Homo sapiens decorin variant A protein. 40 0.008
BC047905-1|AAH47905.2| 915|Homo sapiens leucine-rich repeat-con... 40 0.011
AY358119-1|AAQ88486.1| 915|Homo sapiens gonadotropin receptor p... 40 0.011
AL356953-5|CAI15931.1| 232|Homo sapiens leucine-rich repeat-con... 40 0.011
AL356953-3|CAI15929.1| 915|Homo sapiens leucine-rich repeat-con... 40 0.011
AL356953-1|CAI15927.1| 967|Homo sapiens leucine-rich repeat-con... 40 0.011
AB049405-1|BAB39854.1| 928|Homo sapiens VTS20631 protein. 40 0.011
Z93015-1|CAI42364.1| 481|Homo sapiens nyctalopin protein. 40 0.015
BC112242-1|AAI12243.1| 481|Homo sapiens nyctalopin protein. 40 0.015
BC111745-1|AAI11746.1| 653|Homo sapiens leucine rich repeat con... 40 0.015
BC111561-1|AAI11562.1| 653|Homo sapiens leucine rich repeat con... 40 0.015
BC036337-1|AAH36337.1| 811|Homo sapiens KIAA0644 gene product p... 40 0.015
AY358307-1|AAQ88674.1| 653|Homo sapiens NAG14 protein. 40 0.015
AK172751-1|BAD18737.1| 653|Homo sapiens protein ( Homo sapiens ... 40 0.015
AJ297858-1|CAC82651.1| 649|Homo sapiens hypothetical protein pr... 40 0.015
AJ278865-1|CAC19014.1| 481|Homo sapiens leucine-rich repeat pro... 40 0.015
AF254868-1|AAG42685.1| 481|Homo sapiens nyctalopin protein. 40 0.015
AF196976-1|AAG28019.2| 653|Homo sapiens brain tumor associated ... 40 0.015
AB014544-1|BAA31619.2| 887|Homo sapiens KIAA0644 protein protein. 40 0.015
BC028292-1|AAH28292.1| 402|Homo sapiens PODN protein protein. 39 0.019
J05158-1|AAA51921.2| 545|Homo sapiens carboxypeptidase N precur... 39 0.026
BC131897-1|AAI31898.1| 420|Homo sapiens LRRC4B protein protein. 39 0.026
BC032460-1|AAH32460.1| 634|Homo sapiens LRRC4B protein protein. 39 0.026
BC031569-1|AAH31569.2| 545|Homo sapiens carboxypeptidase N, pol... 39 0.026
AY899851-1|AAX85199.1| 730|Homo sapiens LGR8.1 protein. 39 0.026
BC047653-1|AAH47653.1| 656|Homo sapiens PHLPP protein protein. 38 0.034
AY358115-1|AAQ88482.1| 593|Homo sapiens DAAT9248 protein. 38 0.034
AL589765-16|CAI17178.1| 593|Homo sapiens leucine rich repeat an... 38 0.034
AL356953-4|CAI15930.1| 828|Homo sapiens leucine-rich repeat-con... 38 0.034
AF190501-1|AAG17168.1| 828|Homo sapiens leucine-rich repeat-con... 38 0.034
BC068541-1|AAH68541.1| 713|Homo sapiens leucine rich repeat neu... 38 0.045
BC034047-1|AAH34047.1| 713|Homo sapiens leucine rich repeat neu... 38 0.045
AY358290-1|AAQ88657.1| 713|Homo sapiens GAC1 protein. 38 0.045
AL512306-1|CAI14096.1| 713|Homo sapiens leucine rich repeat neu... 38 0.045
AF245702-1|AAF78035.1| 1049|Homo sapiens toll-like receptor 7 pr... 38 0.045
AF030435-1|AAC39792.1| 713|Homo sapiens glioma amplified on chr... 38 0.045
M65153-1|AAA52287.1| 394|Homo sapiens biglycan protein. 38 0.059
BC113617-1|AAI13618.1| 757|Homo sapiens relaxin/insulin-like fa... 38 0.059
BC112142-1|AAI12143.1| 757|Homo sapiens leucine-rich repeat-con... 38 0.059
BC020870-1|AAH20870.1| 649|Homo sapiens fibronectin leucine ric... 38 0.059
AY899850-1|AAX85198.1| 724|Homo sapiens LGR7.10 protein. 38 0.059
AY899849-1|AAX85197.1| 709|Homo sapiens LGR7.2 protein. 38 0.059
AY358319-1|AAQ88685.1| 649|Homo sapiens FLRT3 protein. 38 0.059
AL132826-1|CAB86687.1| 649|Homo sapiens fibronectin leucine ric... 38 0.059
AK074909-1|BAC11284.1| 649|Homo sapiens protein ( Homo sapiens ... 38 0.059
AK074883-1|BAC11265.1| 627|Homo sapiens protein ( Homo sapiens ... 38 0.059
AK027694-1|BAB55303.1| 623|Homo sapiens protein ( Homo sapiens ... 38 0.059
AK027297-1|BAB55023.1| 649|Homo sapiens protein ( Homo sapiens ... 38 0.059
AF190500-1|AAG17167.1| 757|Homo sapiens leucine-rich repeat-con... 38 0.059
AF169677-1|AAF28461.1| 649|Homo sapiens leucine-rich repeat tra... 38 0.059
AC108017-1|AAY41039.1| 260|Homo sapiens unknown protein. 38 0.059
AB040902-1|BAA95993.1| 662|Homo sapiens KIAA1469 protein protein. 38 0.059
BC109111-1|AAI09112.1| 811|Homo sapiens TLR10 protein protein. 37 0.078
BC089406-1|AAH89406.1| 811|Homo sapiens TLR10 protein protein. 37 0.078
AY358300-1|AAQ88667.1| 811|Homo sapiens TLR10 protein. 37 0.078
AK092954-1|BAC04007.1| 325|Homo sapiens protein ( Homo sapiens ... 37 0.078
AF296673-1|AAK26744.1| 811|Homo sapiens toll-like receptor 10 p... 37 0.078
BC109112-1|AAI09113.1| 811|Homo sapiens TLR10 protein protein. 37 0.10
BC034051-1|AAH34051.1| 1099|Homo sapiens serine/threonine kinase... 37 0.10
AF450267-1|AAL49726.1| 1099|Homo sapiens LKB1-interacting protei... 37 0.10
AB067485-1|BAB67791.1| 1013|Homo sapiens KIAA1898 protein protein. 37 0.10
BC009436-1|AAH09436.1| 610|Homo sapiens Unknown (protein for IM... 36 0.14
AY358116-1|AAQ88483.1| 548|Homo sapiens LGI3 protein. 36 0.14
AJ487961-1|CAD32308.1| 548|Homo sapiens LGI1-like protein 4 pro... 36 0.14
AJ487518-1|CAD31786.1| 548|Homo sapiens leucine-rich glioma ina... 36 0.14
AF467956-1|AAM49554.1| 548|Homo sapiens LGI3 protein. 36 0.14
AB209379-1|BAD92616.1| 245|Homo sapiens hypothetical protein DK... 36 0.14
AB208943-1|BAD92180.1| 627|Homo sapiens leucine-rich repeat-con... 36 0.14
BC029858-1|AAH29858.1| 343|Homo sapiens leucine rich repeat con... 36 0.24
BC022500-1|AAH22500.1| 557|Homo sapiens leucine-rich, glioma in... 36 0.24
AY358885-1|AAQ89244.1| 557|Homo sapiens LGI1 protein. 36 0.24
AL358154-2|CAI14982.1| 557|Homo sapiens leucine-rich, glioma in... 36 0.24
AL358154-1|CAI14981.1| 291|Homo sapiens leucine-rich, glioma in... 36 0.24
AL157396-3|CAH73838.1| 557|Homo sapiens leucine-rich, glioma in... 36 0.24
AL157396-2|CAH73837.1| 291|Homo sapiens leucine-rich, glioma in... 36 0.24
AK223535-1|BAD97255.1| 343|Homo sapiens leucine-rich B7 protein... 36 0.24
AF473548-1|AAM22074.1| 291|Homo sapiens leucine-rich glioma ina... 36 0.24
AF055636-1|AAC99316.1| 557|Homo sapiens leucine-rich glioma-ina... 36 0.24
Y08200-1|CAA69382.1| 567|Homo sapiens rab geranylgeranyl transf... 35 0.31
CR541797-1|CAG46596.1| 567|Homo sapiens RABGGTA protein. 35 0.31
BC003093-1|AAH03093.1| 567|Homo sapiens Rab geranylgeranyltrans... 35 0.31
X72913-1|CAA51418.1| 376|Homo sapiens fibromodulin protein. 35 0.42
BC050097-1|AAH50097.1| 383|Homo sapiens LRRC27 protein protein. 35 0.42
AL590105-8|CAI13019.1| 468|Homo sapiens novel protein protein. 35 0.42
AL590105-7|CAI13018.1| 257|Homo sapiens novel protein protein. 35 0.42
AL590105-6|CAI13017.1| 530|Homo sapiens novel protein protein. 35 0.42
AL590105-5|CAI13016.1| 383|Homo sapiens novel protein protein. 35 0.42
AK098652-1|BAC05366.1| 383|Homo sapiens protein ( Homo sapiens ... 35 0.42
AK093250-1|BAC04108.1| 468|Homo sapiens protein ( Homo sapiens ... 35 0.42
AB051461-1|BAB21765.1| 538|Homo sapiens KIAA1674 protein protein. 35 0.42
AB033011-1|BAA86499.1| 403|Homo sapiens KIAA1185 protein protein. 35 0.42
Z24680-1|CAA80847.1| 662|Homo sapiens garp protein. 34 0.55
U72508-1|AAC51638.1| 312|Homo sapiens B7 protein. 34 0.55
U47924-13|AAB51319.1| 312|Homo sapiens B7 protein. 34 0.55
BC070079-1|AAH70079.1| 662|Homo sapiens LRRC32 protein protein. 34 0.55
BC052210-1|AAH52210.2| 552|Homo sapiens LRRC32 protein protein. 34 0.55
BC035281-1|AAH35281.1| 376|Homo sapiens fibromodulin protein. 34 0.55
BC034947-1|AAH34947.1| 716|Homo sapiens leucine rich repeat neu... 34 0.55
BC032713-1|AAH32713.1| 1032|Homo sapiens toll-like receptor 9 pr... 34 0.55
AY359085-1|AAQ89443.1| 1032|Homo sapiens TLR9 protein. 34 0.55
AY358312-1|AAQ88679.1| 716|Homo sapiens NLRR protein. 34 0.55
AL359837-1|CAH73821.1| 376|Homo sapiens fibromodulin protein. 34 0.55
AF259263-1|AAF72190.1| 975|Homo sapiens toll-like receptor 9 fo... 34 0.55
AF259262-1|AAF72189.1| 1032|Homo sapiens toll-like receptor 9 fo... 34 0.55
AB074161-1|BAE45733.1| 716|Homo sapiens neuronal leucine-rich r... 34 0.55
AB045180-1|BAB19259.1| 1032|Homo sapiens toll-like receptor 9 pr... 34 0.55
AB040930-1|BAA96021.1| 730|Homo sapiens KIAA1497 protein protein. 34 0.55
U88879-1|AAC34134.1| 904|Homo sapiens Toll-like receptor 3 prot... 34 0.73
DQ445682-1|ABE01399.1| 904|Homo sapiens Toll-like receptor 3 is... 34 0.73
BC107493-1|AAI07494.1| 699|Homo sapiens extracellular matrix pr... 34 0.73
BC105958-1|AAI05959.1| 677|Homo sapiens ECM2 protein protein. 34 0.73
BC096335-1|AAH96335.1| 904|Homo sapiens toll-like receptor 3 pr... 34 0.73
BC096334-1|AAH96334.1| 904|Homo sapiens toll-like receptor 3 pr... 34 0.73
BC096333-1|AAH96333.1| 904|Homo sapiens toll-like receptor 3 pr... 34 0.73
BC094737-1|AAH94737.1| 904|Homo sapiens toll-like receptor 3 pr... 34 0.73
BC059372-1|AAH59372.1| 870|Homo sapiens TLR3 protein protein. 34 0.73
BC045113-1|AAH45113.1| 522|Homo sapiens LRRTM1 protein protein. 34 0.73
AY358310-1|AAQ88677.1| 522|Homo sapiens DFLL675 protein. 34 0.73
AY182024-1|AAO67545.1| 522|Homo sapiens leucine-rich repeat tra... 34 0.73
AL157827-4|CAI12589.1| 699|Homo sapiens extracellular matrix pr... 34 0.73
AL137848-1|CAI16693.1| 699|Homo sapiens extracellular matrix pr... 34 0.73
AK128098-1|BAC87273.1| 1185|Homo sapiens protein ( Homo sapiens ... 34 0.73
AK056644-1|BAB71240.1| 522|Homo sapiens protein ( Homo sapiens ... 34 0.73
AB011792-1|BAA33958.1| 699|Homo sapiens extracellular matrix pr... 34 0.73
DQ470079-1|ABF06637.1| 127|Homo sapiens toll-like receptor 3 pr... 33 0.96
DQ470078-1|ABF06636.1| 127|Homo sapiens toll-like receptor 3 pr... 33 0.96
DQ470077-1|ABF06635.1| 127|Homo sapiens toll-like receptor 3 pr... 33 0.96
DQ470076-1|ABF06634.1| 127|Homo sapiens toll-like receptor 3 pr... 33 0.96
DQ470075-1|ABF06633.1| 127|Homo sapiens toll-like receptor 3 pr... 33 0.96
BC068590-1|AAH68590.1| 778|Homo sapiens LOC150356 protein protein. 33 0.96
BC048421-1|AAH48421.1| 453|Homo sapiens LOC150356 protein protein. 33 0.96
BC040188-1|AAH40188.1| 692|Homo sapiens LOC150356 protein protein. 33 0.96
AY029183-1|AAK31796.1| 798|Homo sapiens SLIT1 isoform B protein. 33 0.96
AL512424-3|CAI14257.1| 409|Homo sapiens slit homolog 1 (Drosoph... 33 0.96
AL512424-2|CAI14256.1| 380|Homo sapiens slit homolog 1 (Drosoph... 33 0.96
AL512424-1|CAI14255.1| 782|Homo sapiens slit homolog 1 (Drosoph... 33 0.96
AL035681-1|CAI22653.1| 762|Homo sapiens protein ( Human DNA seq... 33 0.96
BC087848-1|AAH87848.1| 261|Homo sapiens LGI4 protein protein. 33 1.3
AY358121-1|AAQ88488.1| 261|Homo sapiens LGI4 protein. 33 1.3
AJ487959-1|CAD32306.1| 537|Homo sapiens LGI1-like protein 3 pro... 33 1.3
AJ487519-1|CAD31787.1| 537|Homo sapiens leucine-rich glioma ina... 33 1.3
AF467954-1|AAM49552.1| 537|Homo sapiens LGI4 protein. 33 1.3
BC109119-1|AAI09120.1| 858|Homo sapiens TLR5 protein protein. 33 1.7
BC087849-1|AAH87849.1| 259|Homo sapiens LRRC3B protein protein. 33 1.7
BC067784-1|AAH67784.1| 259|Homo sapiens leucine rich repeat con... 33 1.7
BC040656-1|AAH40656.1| 259|Homo sapiens LRRC3B protein protein. 33 1.7
AY358282-1|AAQ88649.1| 259|Homo sapiens NLVD195 protein. 33 1.7
AF396933-1|AAK84157.1| 259|Homo sapiens LRP15 protein. 33 1.7
AF245704-1|AAF78037.1| 1032|Homo sapiens toll-like receptor 9 pr... 33 1.7
BX537976-1|CAD97940.1| 693|Homo sapiens hypothetical protein pr... 32 2.9
BC130290-1|AAI30291.1| 660|Homo sapiens fibronectin leucine ric... 31 3.9
BC126249-1|AAI26250.1| 660|Homo sapiens fibronectin leucine ric... 31 3.9
BC080586-1|AAH80586.1| 743|Homo sapiens MXRA5 protein protein. 31 3.9
BC071561-1|AAH71561.1| 1070|Homo sapiens LRIG1 protein protein. 31 3.9
BC064986-1|AAH64986.1| 743|Homo sapiens MXRA5 protein protein. 31 3.9
BC011846-1|AAH11846.1| 743|Homo sapiens MXRA5 protein protein. 31 3.9
>BC029118-1|AAH29118.1| 371|Homo sapiens leucine rich repeat
containing 2 protein.
Length = 371
Score = 106 bits (255), Expect = 9e-23
Identities = 65/216 (30%), Positives = 99/216 (45%), Gaps = 1/216 (0%)
Frame = +2
Query: 161 LNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIG 340
L+G TE+P L + Y+ I I P P EIG
Sbjct: 105 LSGEHWTELPDSLKEQTHLREWYISNTLIQIIPTYIQLFQAMRILDLPKNQISHLPAEIG 164
Query: 341 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCN-RIGLKEIPKEIGKLTQLDTFGARGN 517
LKNL LN+ +N L + PE+GD E LE C+ + L E+P E+ L Q+ N
Sbjct: 165 CLKNLKELNVGFNYLKSIPPELGDCENLERLDCSGNLELMELPFELSNLKQVTFVDISAN 224
Query: 518 ELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKE 697
+ ++P + ++ L+WL + +N + LP +DR+ L L N+L P S+L K+
Sbjct: 225 KFSSVPICVLRMSNLQWLDISSNNLTDLPQDIDRLEELQSFLLYKNKLTYLPYSMLNLKK 284
Query: 698 LMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
L L ++ + + +P L S P L + L NPI
Sbjct: 285 LTLLVVSGDHLVELPTALCDSSTP-LKFVSLMDNPI 319
>AK223440-1|BAD97160.1| 371|Homo sapiens leucine rich repeat
containing 2 variant protein.
Length = 371
Score = 106 bits (255), Expect = 9e-23
Identities = 65/216 (30%), Positives = 99/216 (45%), Gaps = 1/216 (0%)
Frame = +2
Query: 161 LNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIG 340
L+G TE+P L + Y+ I I P P EIG
Sbjct: 105 LSGEHWTELPDSLKEQTHLREWYISNTLIQIIPTYIQLFQAMRILDLPKNQISHLPAEIG 164
Query: 341 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCN-RIGLKEIPKEIGKLTQLDTFGARGN 517
LKNL LN+ +N L + PE+GD E LE C+ + L E+P E+ L Q+ N
Sbjct: 165 CLKNLKELNVGFNYLKSIPPELGDCENLERLDCSGNLELMELPFELSNLKQVTFVDISAN 224
Query: 518 ELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKE 697
+ ++P + ++ L+WL + +N + LP +DR+ L L N+L P S+L K+
Sbjct: 225 KFSSVPICVLRMSNLQWLDISSNNLTDLPQDIDRLEELQSFLLYKNKLTYLPYSMLNLKK 284
Query: 698 LMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
L L ++ + + +P L S P L + L NPI
Sbjct: 285 LTLLVVSGDHLVELPTALCDSSTP-LKFVSLMDNPI 319
>AK057808-1|BAB71585.1| 371|Homo sapiens protein ( Homo sapiens
cDNA FLJ25079 fis, clone CBL07055. ).
Length = 371
Score = 106 bits (255), Expect = 9e-23
Identities = 65/216 (30%), Positives = 99/216 (45%), Gaps = 1/216 (0%)
Frame = +2
Query: 161 LNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIG 340
L+G TE+P L + Y+ I I P P EIG
Sbjct: 105 LSGEHWTELPDSLKEQTHLREWYISNTLIQIIPTYIQLFQAMRILDLPKNQISHLPAEIG 164
Query: 341 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCN-RIGLKEIPKEIGKLTQLDTFGARGN 517
LKNL LN+ +N L + PE+GD E LE C+ + L E+P E+ L Q+ N
Sbjct: 165 CLKNLKELNVGFNYLKSIPPELGDCENLERLDCSGNLELMELPFELSNLKQVTFVDISAN 224
Query: 518 ELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKE 697
+ ++P + ++ L+WL + +N + LP +DR+ L L N+L P S+L K+
Sbjct: 225 KFSSVPICVLRMSNLQWLDISSNNLTDLPQDIDRLEELQSFLLYKNKLTYLPYSMLNLKK 284
Query: 698 LMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
L L ++ + + +P L S P L + L NPI
Sbjct: 285 LTLLVVSGDHLVELPTALCDSSTP-LKFVSLMDNPI 319
>AJ308569-1|CAC33442.1| 371|Homo sapiens leucine-rich
repeat-containing 2 protein protein.
Length = 371
Score = 106 bits (254), Expect = 1e-22
Identities = 65/216 (30%), Positives = 99/216 (45%), Gaps = 1/216 (0%)
Frame = +2
Query: 161 LNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIG 340
L+G TE+P L + Y+ I I P P EIG
Sbjct: 105 LSGEHWTELPDSLKEQTHLREWYISNTLIQIIPTYIQLFQEMRILDLPKNQISHLPAEIG 164
Query: 341 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCN-RIGLKEIPKEIGKLTQLDTFGARGN 517
LKNL LN+ +N L + PE+GD E LE C+ + L E+P E+ L Q+ N
Sbjct: 165 CLKNLKELNVGFNYLKSIPPELGDCENLERLDCSGNLELMELPFELSNLKQVTFVDISAN 224
Query: 518 ELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKE 697
+ ++P + ++ L+WL + +N + LP +DR+ L L N+L P S+L K+
Sbjct: 225 KFSSVPICVLRMSNLQWLDISSNNLTDLPQDIDRLEELQSFLLYKNKLTYLPYSMLNLKK 284
Query: 698 LMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
L L ++ + + +P L S P L + L NPI
Sbjct: 285 LTLLVVSGDHLVELPTALCDSSTP-LKFVSLMDNPI 319
>BC115015-1|AAI15016.1| 1367|Homo sapiens ERBB2IP protein protein.
Length = 1367
Score = 98.3 bits (234), Expect = 3e-20
Identities = 59/184 (32%), Positives = 90/184 (48%)
Frame = +2
Query: 176 ITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 355
+T IPG + + ++ +L + KN I + P IG+LKN+
Sbjct: 219 LTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPETIGSLKNI 278
Query: 356 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 535
L + N L L IG L +E C+ ++ +P IG+LT L TF A N L+ +P
Sbjct: 279 TTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLP 338
Query: 536 EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQL 715
E+ S + L L +N++ETLP+ M M L NL +NRL+ P S K ++L + L
Sbjct: 339 PEIGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSDNRLKNLPFSFTKLQQLTAMWL 398
Query: 716 NSNQ 727
+ NQ
Sbjct: 399 SDNQ 402
Score = 85.4 bits (202), Expect = 2e-16
Identities = 53/201 (26%), Positives = 87/201 (43%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ +I E+P L+ C + L L N ++ P P
Sbjct: 51 LYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPEN 110
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
I N K L + S NP++ L L L + N L+ +P +LT+L R
Sbjct: 111 IKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFDRLTKLQILELRE 170
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N+LK +P+ M L +L L L +N+ +P+ +++++ L + NRL P I K
Sbjct: 171 NQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLK 230
Query: 695 ELMFLQLNSNQISSVPANLDT 757
+L +L ++ N I V + T
Sbjct: 231 QLTYLDVSKNNIEMVEEGIST 251
Score = 77.4 bits (182), Expect = 6e-14
Identities = 49/200 (24%), Positives = 83/200 (41%)
Frame = +2
Query: 152 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
+LSL ++T +P + + + L + KN I FP P
Sbjct: 73 KLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPD 132
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
L NL L L+ L L L KL+ LK +PK + +LTQL+
Sbjct: 133 GFSQLLNLTQLYLNDAFLEFLPANFDRLTKLQILELRENQLKMLPKTMNRLTQLERLDLG 192
Query: 512 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 691
NE +PE + L+ L+ ++ N++ +P + + L + ++ N +E I C
Sbjct: 193 SNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTC 252
Query: 692 KELMFLQLNSNQISSVPANL 751
+ L L L+SN + +P +
Sbjct: 253 ENLQDLLLSSNSLQQLPETI 272
Score = 60.5 bits (140), Expect = 7e-09
Identities = 50/199 (25%), Positives = 80/199 (40%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
+S NG I E P + C + + N IS P P
Sbjct: 99 VSKNG--IQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPAN 156
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
L L L L N L +L + L +LE E+P+ + +L+ L F
Sbjct: 157 FDRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDA 216
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N L IP + SL +L +L + N IE + + + L L +N L+Q P +I K
Sbjct: 217 NRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPETIGSLK 276
Query: 695 ELMFLQLNSNQISSVPANL 751
+ L+++ NQ+ +P ++
Sbjct: 277 NITTLKIDENQLMYLPDSI 295
Score = 59.3 bits (137), Expect = 2e-08
Identities = 40/157 (25%), Positives = 70/157 (44%), Gaps = 1/157 (0%)
Frame = +2
Query: 338 GNLKNLVNLNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
G + + L+ S+ L + EI EK LE + + ++E+PK++ L
Sbjct: 19 GEEETVTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPD 78
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N+L T+P + +L LR L + N I+ P+ + L N + + P +
Sbjct: 79 NDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLL 138
Query: 695 ELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
L L LN + +PAN D + L +++LR N +
Sbjct: 139 NLTQLYLNDAFLEFLPANFDR--LTKLQILELRENQL 173
Score = 57.2 bits (132), Expect = 7e-08
Identities = 35/149 (23%), Positives = 63/149 (42%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ + ++P + + + L + +N++ P P+
Sbjct: 258 LLLSSNSLQQLPETIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSS 317
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
IG L NL +N L L PEIG + + + + L+ +P+E+G + +L
Sbjct: 318 IGQLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSD 377
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETL 601
N LK +P T L +L + L +NQ + L
Sbjct: 378 NRLKNLPFSFTKLQQLTAMWLSDNQSKPL 406
Score = 54.8 bits (126), Expect = 4e-07
Identities = 40/201 (19%), Positives = 81/201 (40%)
Frame = +2
Query: 149 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXP 328
++L LN + +P +++ L L +N++ + P P
Sbjct: 141 TQLYLNDAFLEFLPANFDRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVP 200
Query: 329 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGA 508
+ L L + N L + IG L++L ++ ++ + + I L
Sbjct: 201 EVLEQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLL 260
Query: 509 RGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILK 688
N L+ +PE + SL + L ++ NQ+ LPD++ + ++ + N +E PSSI +
Sbjct: 261 SSNSLQQLPETIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQ 320
Query: 689 CKELMFLQLNSNQISSVPANL 751
L + N + +P +
Sbjct: 321 LTNLRTFAADHNYLQQLPPEI 341
Score = 51.6 bits (118), Expect = 3e-06
Identities = 41/164 (25%), Positives = 67/164 (40%), Gaps = 1/164 (0%)
Frame = +2
Query: 326 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
P EI K L L L N + L ++ + + L L +P I L L
Sbjct: 38 PKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLREL 97
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 682
N ++ PE + + L + N I LPD ++ L L + LE P++
Sbjct: 98 DVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANF 157
Query: 683 LKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
+ +L L+L NQ+ +P ++ + L +DL SN E+
Sbjct: 158 DRLTKLQILELRENQLKMLPKTMNR--LTQLERLDLGSNEFTEV 199
>BC115012-1|AAI15013.1| 1371|Homo sapiens erbb2 interacting protein
protein.
Length = 1371
Score = 98.3 bits (234), Expect = 3e-20
Identities = 59/184 (32%), Positives = 90/184 (48%)
Frame = +2
Query: 176 ITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 355
+T IPG + + ++ +L + KN I + P IG+LKN+
Sbjct: 219 LTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPEPIGSLKNI 278
Query: 356 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 535
L + N L L IG L +E C+ ++ +P IG+LT L TF A N L+ +P
Sbjct: 279 TTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLP 338
Query: 536 EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQL 715
E+ S + L L +N++ETLP+ M M L NL +NRL+ P S K ++L + L
Sbjct: 339 PEIGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSDNRLKNLPFSFTKLQQLTAMWL 398
Query: 716 NSNQ 727
+ NQ
Sbjct: 399 SDNQ 402
Score = 90.6 bits (215), Expect = 6e-18
Identities = 60/223 (26%), Positives = 97/223 (43%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ +I E+P L+ C + L L N ++ P P
Sbjct: 51 LYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPEN 110
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
I N K L + S NP++ L L L + N L+ +P G+LT+L R
Sbjct: 111 IKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRE 170
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N+LK +P+ M L +L L L +N+ +P+ +++++ L + NRL P I K
Sbjct: 171 NQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLK 230
Query: 695 ELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELSHP 823
+L +L ++ N I V + T L + L SN + +L P
Sbjct: 231 QLTYLDVSKNNIEMVEEGIST--CENLQDLLLSSNSLQQLPEP 271
Score = 62.5 bits (145), Expect = 2e-09
Identities = 51/199 (25%), Positives = 80/199 (40%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
+S NG I E P + C + + N IS P P
Sbjct: 99 VSKNG--IQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPAN 156
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
G L L L L N L +L + L +LE E+P+ + +L+ L F
Sbjct: 157 FGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDA 216
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N L IP + SL +L +L + N IE + + + L L +N L+Q P I K
Sbjct: 217 NRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPEPIGSLK 276
Query: 695 ELMFLQLNSNQISSVPANL 751
+ L+++ NQ+ +P ++
Sbjct: 277 NITTLKIDENQLMYLPDSI 295
Score = 56.4 bits (130), Expect = 1e-07
Identities = 39/157 (24%), Positives = 69/157 (43%), Gaps = 1/157 (0%)
Frame = +2
Query: 338 GNLKNLVNLNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
G + + L+ S+ L + EI EK LE + + ++E+PK++ L
Sbjct: 19 GEEETVTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPD 78
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N+L T+P + +L LR L + N I+ P+ + L N + + P +
Sbjct: 79 NDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLL 138
Query: 695 ELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
L L LN + +PAN + L +++LR N +
Sbjct: 139 NLTQLYLNDAFLEFLPANF--GRLTKLQILELRENQL 173
Score = 56.4 bits (130), Expect = 1e-07
Identities = 35/149 (23%), Positives = 63/149 (42%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ + ++P + + + L + +N++ P P+
Sbjct: 258 LLLSSNSLQQLPEPIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSS 317
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
IG L NL +N L L PEIG + + + + L+ +P+E+G + +L
Sbjct: 318 IGQLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSD 377
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETL 601
N LK +P T L +L + L +NQ + L
Sbjct: 378 NRLKNLPFSFTKLQQLTAMWLSDNQSKPL 406
Score = 54.8 bits (126), Expect = 4e-07
Identities = 40/201 (19%), Positives = 81/201 (40%)
Frame = +2
Query: 149 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXP 328
++L LN + +P +++ L L +N++ + P P
Sbjct: 141 TQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVP 200
Query: 329 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGA 508
+ L L + N L + IG L++L ++ ++ + + I L
Sbjct: 201 EVLEQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLL 260
Query: 509 RGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILK 688
N L+ +PE + SL + L ++ NQ+ LPD++ + ++ + N +E PSSI +
Sbjct: 261 SSNSLQQLPEPIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQ 320
Query: 689 CKELMFLQLNSNQISSVPANL 751
L + N + +P +
Sbjct: 321 LTNLRTFAADHNYLQQLPPEI 341
Score = 51.6 bits (118), Expect = 3e-06
Identities = 41/164 (25%), Positives = 67/164 (40%), Gaps = 1/164 (0%)
Frame = +2
Query: 326 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
P EI K L L L N + L ++ + + L L +P I L L
Sbjct: 38 PKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLREL 97
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 682
N ++ PE + + L + N I LPD ++ L L + LE P++
Sbjct: 98 DVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANF 157
Query: 683 LKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
+ +L L+L NQ+ +P ++ + L +DL SN E+
Sbjct: 158 GRLTKLQILELRENQLKMLPKTMNR--LTQLERLDLGSNEFTEV 199
>BC050692-1|AAH50692.1| 633|Homo sapiens ERBB2IP protein protein.
Length = 633
Score = 98.3 bits (234), Expect = 3e-20
Identities = 59/184 (32%), Positives = 90/184 (48%)
Frame = +2
Query: 176 ITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 355
+T IPG + + ++ +L + KN I + P IG+LKN+
Sbjct: 219 LTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPETIGSLKNI 278
Query: 356 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 535
L + N L L IG L +E C+ ++ +P IG+LT L TF A N L+ +P
Sbjct: 279 TTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLP 338
Query: 536 EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQL 715
E+ S + L L +N++ETLP+ M M L NL +NRL+ P S K ++L + L
Sbjct: 339 PEIGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSDNRLKNLPFSFTKLQQLTAMWL 398
Query: 716 NSNQ 727
+ NQ
Sbjct: 399 SDNQ 402
Score = 88.2 bits (209), Expect = 3e-17
Identities = 54/201 (26%), Positives = 88/201 (43%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ +I E+P L+ C + L L N ++ P P
Sbjct: 51 LYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPEN 110
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
I N K L + S NP++ L L L + N L+ +P G+LT+L R
Sbjct: 111 IKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRE 170
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N+LK +P+ M L +L L L +N+ +P+ +++++ L + NRL P I K
Sbjct: 171 NQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLK 230
Query: 695 ELMFLQLNSNQISSVPANLDT 757
+L +L ++ N I V + T
Sbjct: 231 QLTYLDVSKNNIEMVEEGIST 251
Score = 80.2 bits (189), Expect = 8e-15
Identities = 50/200 (25%), Positives = 84/200 (42%)
Frame = +2
Query: 152 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
+LSL ++T +P + + + L + KN I FP P
Sbjct: 73 KLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPD 132
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
L NL L L+ L L G L KL+ LK +PK + +LTQL+
Sbjct: 133 GFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLG 192
Query: 512 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 691
NE +PE + L+ L+ ++ N++ +P + + L + ++ N +E I C
Sbjct: 193 SNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTC 252
Query: 692 KELMFLQLNSNQISSVPANL 751
+ L L L+SN + +P +
Sbjct: 253 ENLQDLLLSSNSLQQLPETI 272
Score = 63.3 bits (147), Expect = 1e-09
Identities = 51/199 (25%), Positives = 81/199 (40%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
+S NG I E P + C + + N IS P P
Sbjct: 99 VSKNG--IQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPAN 156
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
G L L L L N L +L + L +LE E+P+ + +L+ L F
Sbjct: 157 FGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDA 216
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N L IP + SL +L +L + N IE + + + L L +N L+Q P +I K
Sbjct: 217 NRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPETIGSLK 276
Query: 695 ELMFLQLNSNQISSVPANL 751
+ L+++ NQ+ +P ++
Sbjct: 277 NITTLKIDENQLMYLPDSI 295
Score = 57.2 bits (132), Expect = 7e-08
Identities = 35/149 (23%), Positives = 63/149 (42%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ + ++P + + + L + +N++ P P+
Sbjct: 258 LLLSSNSLQQLPETIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSS 317
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
IG L NL +N L L PEIG + + + + L+ +P+E+G + +L
Sbjct: 318 IGQLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSD 377
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETL 601
N LK +P T L +L + L +NQ + L
Sbjct: 378 NRLKNLPFSFTKLQQLTAMWLSDNQSKPL 406
Score = 56.4 bits (130), Expect = 1e-07
Identities = 39/157 (24%), Positives = 69/157 (43%), Gaps = 1/157 (0%)
Frame = +2
Query: 338 GNLKNLVNLNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
G + + L+ S+ L + EI EK LE + + ++E+PK++ L
Sbjct: 19 GEEETVTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPD 78
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N+L T+P + +L LR L + N I+ P+ + L N + + P +
Sbjct: 79 NDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLL 138
Query: 695 ELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
L L LN + +PAN + L +++LR N +
Sbjct: 139 NLTQLYLNDAFLEFLPANF--GRLTKLQILELRENQL 173
Score = 54.8 bits (126), Expect = 4e-07
Identities = 40/201 (19%), Positives = 81/201 (40%)
Frame = +2
Query: 149 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXP 328
++L LN + +P +++ L L +N++ + P P
Sbjct: 141 TQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVP 200
Query: 329 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGA 508
+ L L + N L + IG L++L ++ ++ + + I L
Sbjct: 201 EVLEQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLL 260
Query: 509 RGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILK 688
N L+ +PE + SL + L ++ NQ+ LPD++ + ++ + N +E PSSI +
Sbjct: 261 SSNSLQQLPETIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQ 320
Query: 689 CKELMFLQLNSNQISSVPANL 751
L + N + +P +
Sbjct: 321 LTNLRTFAADHNYLQQLPPEI 341
Score = 51.6 bits (118), Expect = 3e-06
Identities = 41/164 (25%), Positives = 67/164 (40%), Gaps = 1/164 (0%)
Frame = +2
Query: 326 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
P EI K L L L N + L ++ + + L L +P I L L
Sbjct: 38 PKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLREL 97
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 682
N ++ PE + + L + N I LPD ++ L L + LE P++
Sbjct: 98 DVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANF 157
Query: 683 LKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
+ +L L+L NQ+ +P ++ + L +DL SN E+
Sbjct: 158 GRLTKLQILELRENQLKMLPKTMNR--LTQLERLDLGSNEFTEV 199
>AF276423-1|AAK69431.1| 1412|Homo sapiens densin-180-like protein
protein.
Length = 1412
Score = 98.3 bits (234), Expect = 3e-20
Identities = 59/184 (32%), Positives = 90/184 (48%)
Frame = +2
Query: 176 ITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 355
+T IPG + + ++ +L + KN I + P IG+LKN+
Sbjct: 219 LTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPETIGSLKNI 278
Query: 356 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 535
L + N L L IG L +E C+ ++ +P IG+LT L TF A N L+ +P
Sbjct: 279 TTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLP 338
Query: 536 EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQL 715
E+ S + L L +N++ETLP+ M M L NL +NRL+ P S K ++L + L
Sbjct: 339 PEIGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSDNRLKNLPFSFTKLQQLTAMWL 398
Query: 716 NSNQ 727
+ NQ
Sbjct: 399 SDNQ 402
Score = 88.2 bits (209), Expect = 3e-17
Identities = 54/201 (26%), Positives = 88/201 (43%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ +I E+P L+ C + L L N ++ P P
Sbjct: 51 LYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPEN 110
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
I N K L + S NP++ L L L + N L+ +P G+LT+L R
Sbjct: 111 IKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRE 170
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N+LK +P+ M L +L L L +N+ +P+ +++++ L + NRL P I K
Sbjct: 171 NQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLK 230
Query: 695 ELMFLQLNSNQISSVPANLDT 757
+L +L ++ N I V + T
Sbjct: 231 QLTYLDVSKNNIEMVEEGIST 251
Score = 80.2 bits (189), Expect = 8e-15
Identities = 50/200 (25%), Positives = 84/200 (42%)
Frame = +2
Query: 152 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
+LSL ++T +P + + + L + KN I FP P
Sbjct: 73 KLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPD 132
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
L NL L L+ L L G L KL+ LK +PK + +LTQL+
Sbjct: 133 GFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLG 192
Query: 512 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 691
NE +PE + L+ L+ ++ N++ +P + + L + ++ N +E I C
Sbjct: 193 SNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTC 252
Query: 692 KELMFLQLNSNQISSVPANL 751
+ L L L+SN + +P +
Sbjct: 253 ENLQDLLLSSNSLQQLPETI 272
Score = 63.3 bits (147), Expect = 1e-09
Identities = 51/199 (25%), Positives = 81/199 (40%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
+S NG I E P + C + + N IS P P
Sbjct: 99 VSKNG--IQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPAN 156
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
G L L L L N L +L + L +LE E+P+ + +L+ L F
Sbjct: 157 FGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDA 216
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N L IP + SL +L +L + N IE + + + L L +N L+Q P +I K
Sbjct: 217 NRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPETIGSLK 276
Query: 695 ELMFLQLNSNQISSVPANL 751
+ L+++ NQ+ +P ++
Sbjct: 277 NITTLKIDENQLMYLPDSI 295
Score = 57.2 bits (132), Expect = 7e-08
Identities = 35/149 (23%), Positives = 63/149 (42%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ + ++P + + + L + +N++ P P+
Sbjct: 258 LLLSSNSLQQLPETIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSS 317
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
IG L NL +N L L PEIG + + + + L+ +P+E+G + +L
Sbjct: 318 IGQLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSD 377
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETL 601
N LK +P T L +L + L +NQ + L
Sbjct: 378 NRLKNLPFSFTKLQQLTAMWLSDNQSKPL 406
Score = 56.4 bits (130), Expect = 1e-07
Identities = 39/157 (24%), Positives = 69/157 (43%), Gaps = 1/157 (0%)
Frame = +2
Query: 338 GNLKNLVNLNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
G + + L+ S+ L + EI EK LE + + ++E+PK++ L
Sbjct: 19 GEEETVTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPD 78
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N+L T+P + +L LR L + N I+ P+ + L N + + P +
Sbjct: 79 NDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLL 138
Query: 695 ELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
L L LN + +PAN + L +++LR N +
Sbjct: 139 NLTQLYLNDAFLEFLPANF--GRLTKLQILELRENQL 173
Score = 54.8 bits (126), Expect = 4e-07
Identities = 40/201 (19%), Positives = 81/201 (40%)
Frame = +2
Query: 149 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXP 328
++L LN + +P +++ L L +N++ + P P
Sbjct: 141 TQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVP 200
Query: 329 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGA 508
+ L L + N L + IG L++L ++ ++ + + I L
Sbjct: 201 EVLEQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLL 260
Query: 509 RGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILK 688
N L+ +PE + SL + L ++ NQ+ LPD++ + ++ + N +E PSSI +
Sbjct: 261 SSNSLQQLPETIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQ 320
Query: 689 CKELMFLQLNSNQISSVPANL 751
L + N + +P +
Sbjct: 321 LTNLRTFAADHNYLQQLPPEI 341
Score = 51.6 bits (118), Expect = 3e-06
Identities = 41/164 (25%), Positives = 67/164 (40%), Gaps = 1/164 (0%)
Frame = +2
Query: 326 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
P EI K L L L N + L ++ + + L L +P I L L
Sbjct: 38 PKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLREL 97
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 682
N ++ PE + + L + N I LPD ++ L L + LE P++
Sbjct: 98 DVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANF 157
Query: 683 LKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
+ +L L+L NQ+ +P ++ + L +DL SN E+
Sbjct: 158 GRLTKLQILELRENQLKMLPKTMNR--LTQLERLDLGSNEFTEV 199
>AF263744-1|AAF77048.1| 1371|Homo sapiens erbb2-interacting protein
ERBIN protein.
Length = 1371
Score = 98.3 bits (234), Expect = 3e-20
Identities = 59/184 (32%), Positives = 90/184 (48%)
Frame = +2
Query: 176 ITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 355
+T IPG + + ++ +L + KN I + P IG+LKN+
Sbjct: 219 LTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPETIGSLKNI 278
Query: 356 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 535
L + N L L IG L +E C+ ++ +P IG+LT L TF A N L+ +P
Sbjct: 279 TTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLP 338
Query: 536 EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQL 715
E+ S + L L +N++ETLP+ M M L NL +NRL+ P S K ++L + L
Sbjct: 339 PEIGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSDNRLKNLPFSFTKLQQLTAMWL 398
Query: 716 NSNQ 727
+ NQ
Sbjct: 399 SDNQ 402
Score = 88.2 bits (209), Expect = 3e-17
Identities = 54/201 (26%), Positives = 88/201 (43%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ +I E+P L+ C + L L N ++ P P
Sbjct: 51 LYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPEN 110
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
I N K L + S NP++ L L L + N L+ +P G+LT+L R
Sbjct: 111 IKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRE 170
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N+LK +P+ M L +L L L +N+ +P+ +++++ L + NRL P I K
Sbjct: 171 NQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLK 230
Query: 695 ELMFLQLNSNQISSVPANLDT 757
+L +L ++ N I V + T
Sbjct: 231 QLTYLDVSKNNIEMVEEGIST 251
Score = 80.2 bits (189), Expect = 8e-15
Identities = 50/200 (25%), Positives = 84/200 (42%)
Frame = +2
Query: 152 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
+LSL ++T +P + + + L + KN I FP P
Sbjct: 73 KLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPD 132
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
L NL L L+ L L G L KL+ LK +PK + +LTQL+
Sbjct: 133 GFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLG 192
Query: 512 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 691
NE +PE + L+ L+ ++ N++ +P + + L + ++ N +E I C
Sbjct: 193 SNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTC 252
Query: 692 KELMFLQLNSNQISSVPANL 751
+ L L L+SN + +P +
Sbjct: 253 ENLQDLLLSSNSLQQLPETI 272
Score = 63.3 bits (147), Expect = 1e-09
Identities = 51/199 (25%), Positives = 81/199 (40%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
+S NG I E P + C + + N IS P P
Sbjct: 99 VSKNG--IQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPAN 156
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
G L L L L N L +L + L +LE E+P+ + +L+ L F
Sbjct: 157 FGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDA 216
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N L IP + SL +L +L + N IE + + + L L +N L+Q P +I K
Sbjct: 217 NRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPETIGSLK 276
Query: 695 ELMFLQLNSNQISSVPANL 751
+ L+++ NQ+ +P ++
Sbjct: 277 NITTLKIDENQLMYLPDSI 295
Score = 57.2 bits (132), Expect = 7e-08
Identities = 35/149 (23%), Positives = 63/149 (42%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ + ++P + + + L + +N++ P P+
Sbjct: 258 LLLSSNSLQQLPETIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSS 317
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
IG L NL +N L L PEIG + + + + L+ +P+E+G + +L
Sbjct: 318 IGQLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSD 377
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETL 601
N LK +P T L +L + L +NQ + L
Sbjct: 378 NRLKNLPFSFTKLQQLTAMWLSDNQSKPL 406
Score = 56.4 bits (130), Expect = 1e-07
Identities = 39/157 (24%), Positives = 69/157 (43%), Gaps = 1/157 (0%)
Frame = +2
Query: 338 GNLKNLVNLNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
G + + L+ S+ L + EI EK LE + + ++E+PK++ L
Sbjct: 19 GEEETVTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPD 78
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N+L T+P + +L LR L + N I+ P+ + L N + + P +
Sbjct: 79 NDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLL 138
Query: 695 ELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
L L LN + +PAN + L +++LR N +
Sbjct: 139 NLTQLYLNDAFLEFLPANF--GRLTKLQILELRENQL 173
Score = 54.8 bits (126), Expect = 4e-07
Identities = 40/201 (19%), Positives = 81/201 (40%)
Frame = +2
Query: 149 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXP 328
++L LN + +P +++ L L +N++ + P P
Sbjct: 141 TQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVP 200
Query: 329 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGA 508
+ L L + N L + IG L++L ++ ++ + + I L
Sbjct: 201 EVLEQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLL 260
Query: 509 RGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILK 688
N L+ +PE + SL + L ++ NQ+ LPD++ + ++ + N +E PSSI +
Sbjct: 261 SSNSLQQLPETIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQ 320
Query: 689 CKELMFLQLNSNQISSVPANL 751
L + N + +P +
Sbjct: 321 LTNLRTFAADHNYLQQLPPEI 341
Score = 51.6 bits (118), Expect = 3e-06
Identities = 41/164 (25%), Positives = 67/164 (40%), Gaps = 1/164 (0%)
Frame = +2
Query: 326 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
P EI K L L L N + L ++ + + L L +P I L L
Sbjct: 38 PKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLREL 97
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 682
N ++ PE + + L + N I LPD ++ L L + LE P++
Sbjct: 98 DVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANF 157
Query: 683 LKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
+ +L L+L NQ+ +P ++ + L +DL SN E+
Sbjct: 158 GRLTKLQILELRENQLKMLPKTMNR--LTQLERLDLGSNEFTEV 199
>AB033051-1|BAA86539.2| 1371|Homo sapiens KIAA1225 protein protein.
Length = 1371
Score = 98.3 bits (234), Expect = 3e-20
Identities = 59/184 (32%), Positives = 90/184 (48%)
Frame = +2
Query: 176 ITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 355
+T IPG + + ++ +L + KN I + P IG+LKN+
Sbjct: 219 LTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPETIGSLKNI 278
Query: 356 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 535
L + N L L IG L +E C+ ++ +P IG+LT L TF A N L+ +P
Sbjct: 279 TTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLP 338
Query: 536 EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQL 715
E+ S + L L +N++ETLP+ M M L NL +NRL+ P S K ++L + L
Sbjct: 339 PEIGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSDNRLKNLPFSFTKLQQLTAMWL 398
Query: 716 NSNQ 727
+ NQ
Sbjct: 399 SDNQ 402
Score = 88.2 bits (209), Expect = 3e-17
Identities = 54/201 (26%), Positives = 88/201 (43%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ +I E+P L+ C + L L N ++ P P
Sbjct: 51 LYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPEN 110
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
I N K L + S NP++ L L L + N L+ +P G+LT+L R
Sbjct: 111 IKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRE 170
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N+LK +P+ M L +L L L +N+ +P+ +++++ L + NRL P I K
Sbjct: 171 NQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLK 230
Query: 695 ELMFLQLNSNQISSVPANLDT 757
+L +L ++ N I V + T
Sbjct: 231 QLTYLDVSKNNIEMVEEGIST 251
Score = 80.2 bits (189), Expect = 8e-15
Identities = 50/200 (25%), Positives = 84/200 (42%)
Frame = +2
Query: 152 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
+LSL ++T +P + + + L + KN I FP P
Sbjct: 73 KLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPD 132
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
L NL L L+ L L G L KL+ LK +PK + +LTQL+
Sbjct: 133 GFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLG 192
Query: 512 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 691
NE +PE + L+ L+ ++ N++ +P + + L + ++ N +E I C
Sbjct: 193 SNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTC 252
Query: 692 KELMFLQLNSNQISSVPANL 751
+ L L L+SN + +P +
Sbjct: 253 ENLQDLLLSSNSLQQLPETI 272
Score = 63.3 bits (147), Expect = 1e-09
Identities = 51/199 (25%), Positives = 81/199 (40%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
+S NG I E P + C + + N IS P P
Sbjct: 99 VSKNG--IQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPAN 156
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
G L L L L N L +L + L +LE E+P+ + +L+ L F
Sbjct: 157 FGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDA 216
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N L IP + SL +L +L + N IE + + + L L +N L+Q P +I K
Sbjct: 217 NRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPETIGSLK 276
Query: 695 ELMFLQLNSNQISSVPANL 751
+ L+++ NQ+ +P ++
Sbjct: 277 NITTLKIDENQLMYLPDSI 295
Score = 57.2 bits (132), Expect = 7e-08
Identities = 35/149 (23%), Positives = 63/149 (42%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ + ++P + + + L + +N++ P P+
Sbjct: 258 LLLSSNSLQQLPETIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSS 317
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
IG L NL +N L L PEIG + + + + L+ +P+E+G + +L
Sbjct: 318 IGQLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSD 377
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETL 601
N LK +P T L +L + L +NQ + L
Sbjct: 378 NRLKNLPFSFTKLQQLTAMWLSDNQSKPL 406
Score = 56.4 bits (130), Expect = 1e-07
Identities = 39/157 (24%), Positives = 69/157 (43%), Gaps = 1/157 (0%)
Frame = +2
Query: 338 GNLKNLVNLNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
G + + L+ S+ L + EI EK LE + + ++E+PK++ L
Sbjct: 19 GEEETVTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPD 78
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N+L T+P + +L LR L + N I+ P+ + L N + + P +
Sbjct: 79 NDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLL 138
Query: 695 ELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
L L LN + +PAN + L +++LR N +
Sbjct: 139 NLTQLYLNDAFLEFLPANF--GRLTKLQILELRENQL 173
Score = 54.8 bits (126), Expect = 4e-07
Identities = 40/201 (19%), Positives = 81/201 (40%)
Frame = +2
Query: 149 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXP 328
++L LN + +P +++ L L +N++ + P P
Sbjct: 141 TQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVP 200
Query: 329 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGA 508
+ L L + N L + IG L++L ++ ++ + + I L
Sbjct: 201 EVLEQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLL 260
Query: 509 RGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILK 688
N L+ +PE + SL + L ++ NQ+ LPD++ + ++ + N +E PSSI +
Sbjct: 261 SSNSLQQLPETIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQ 320
Query: 689 CKELMFLQLNSNQISSVPANL 751
L + N + +P +
Sbjct: 321 LTNLRTFAADHNYLQQLPPEI 341
Score = 51.6 bits (118), Expect = 3e-06
Identities = 41/164 (25%), Positives = 67/164 (40%), Gaps = 1/164 (0%)
Frame = +2
Query: 326 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
P EI K L L L N + L ++ + + L L +P I L L
Sbjct: 38 PKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLREL 97
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 682
N ++ PE + + L + N I LPD ++ L L + LE P++
Sbjct: 98 DVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANF 157
Query: 683 LKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
+ +L L+L NQ+ +P ++ + L +DL SN E+
Sbjct: 158 GRLTKLQILELRENQLKMLPKTMNR--LTQLERLDLGSNEFTEV 199
>BC126464-1|AAI26465.1| 1371|Homo sapiens erbb2 interacting protein
protein.
Length = 1371
Score = 96.7 bits (230), Expect = 9e-20
Identities = 59/184 (32%), Positives = 89/184 (48%)
Frame = +2
Query: 176 ITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 355
+T IPG + + ++ +L + KN I + P IG LKN+
Sbjct: 219 LTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPETIGLLKNI 278
Query: 356 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 535
L + N L L IG L +E C+ ++ +P IG+LT L TF A N L+ +P
Sbjct: 279 TTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLP 338
Query: 536 EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQL 715
E+ S + L L +N++ETLP+ M M L NL +NRL+ P S K ++L + L
Sbjct: 339 PEIGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSDNRLKNLPFSFTKLQQLTAMWL 398
Query: 716 NSNQ 727
+ NQ
Sbjct: 399 SDNQ 402
Score = 88.2 bits (209), Expect = 3e-17
Identities = 54/201 (26%), Positives = 88/201 (43%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ +I E+P L+ C + L L N ++ P P
Sbjct: 51 LYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPEN 110
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
I N K L + S NP++ L L L + N L+ +P G+LT+L R
Sbjct: 111 IKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRE 170
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N+LK +P+ M L +L L L +N+ +P+ +++++ L + NRL P I K
Sbjct: 171 NQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLK 230
Query: 695 ELMFLQLNSNQISSVPANLDT 757
+L +L ++ N I V + T
Sbjct: 231 QLTYLDVSKNNIEMVEEGIST 251
Score = 80.6 bits (190), Expect = 6e-15
Identities = 53/221 (23%), Positives = 92/221 (41%)
Frame = +2
Query: 152 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
+LSL ++T +P + + + L + KN I FP P
Sbjct: 73 KLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPD 132
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
L NL L L+ L L G L KL+ LK +PK + +LTQL+
Sbjct: 133 GFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLG 192
Query: 512 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 691
NE +PE + L+ L+ ++ N++ +P + + L + ++ N +E I C
Sbjct: 193 SNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTC 252
Query: 692 KELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
+ L L L+SN + +P + L+ + + + N + L
Sbjct: 253 ENLQDLLLSSNSLQQLPETI--GLLKNITTLKIDENQLMYL 291
Score = 62.5 bits (145), Expect = 2e-09
Identities = 51/199 (25%), Positives = 81/199 (40%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
+S NG I E P + C + + N IS P P
Sbjct: 99 VSKNG--IQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPAN 156
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
G L L L L N L +L + L +LE E+P+ + +L+ L F
Sbjct: 157 FGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDA 216
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N L IP + SL +L +L + N IE + + + L L +N L+Q P +I K
Sbjct: 217 NRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPETIGLLK 276
Query: 695 ELMFLQLNSNQISSVPANL 751
+ L+++ NQ+ +P ++
Sbjct: 277 NITTLKIDENQLMYLPDSI 295
Score = 56.4 bits (130), Expect = 1e-07
Identities = 39/157 (24%), Positives = 69/157 (43%), Gaps = 1/157 (0%)
Frame = +2
Query: 338 GNLKNLVNLNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
G + + L+ S+ L + EI EK LE + + ++E+PK++ L
Sbjct: 19 GEEETVTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPD 78
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N+L T+P + +L LR L + N I+ P+ + L N + + P +
Sbjct: 79 NDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLL 138
Query: 695 ELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
L L LN + +PAN + L +++LR N +
Sbjct: 139 NLTQLYLNDAFLEFLPANF--GRLTKLQILELRENQL 173
Score = 56.4 bits (130), Expect = 1e-07
Identities = 35/149 (23%), Positives = 62/149 (41%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ + ++P + + L + +N++ P P+
Sbjct: 258 LLLSSNSLQQLPETIGLLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSS 317
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
IG L NL +N L L PEIG + + + + L+ +P+E+G + +L
Sbjct: 318 IGQLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSD 377
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETL 601
N LK +P T L +L + L +NQ + L
Sbjct: 378 NRLKNLPFSFTKLQQLTAMWLSDNQSKPL 406
Score = 52.4 bits (120), Expect = 2e-06
Identities = 39/201 (19%), Positives = 80/201 (39%)
Frame = +2
Query: 149 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXP 328
++L LN + +P +++ L L +N++ + P P
Sbjct: 141 TQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVP 200
Query: 329 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGA 508
+ L L + N L + IG L++L ++ ++ + + I L
Sbjct: 201 EVLEQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLL 260
Query: 509 RGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILK 688
N L+ +PE + L + L ++ NQ+ LPD++ + ++ + N +E PSSI +
Sbjct: 261 SSNSLQQLPETIGLLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQ 320
Query: 689 CKELMFLQLNSNQISSVPANL 751
L + N + +P +
Sbjct: 321 LTNLRTFAADHNYLQQLPPEI 341
Score = 51.6 bits (118), Expect = 3e-06
Identities = 41/164 (25%), Positives = 67/164 (40%), Gaps = 1/164 (0%)
Frame = +2
Query: 326 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
P EI K L L L N + L ++ + + L L +P I L L
Sbjct: 38 PKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLREL 97
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 682
N ++ PE + + L + N I LPD ++ L L + LE P++
Sbjct: 98 DVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANF 157
Query: 683 LKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
+ +L L+L NQ+ +P ++ + L +DL SN E+
Sbjct: 158 GRLTKLQILELRENQLKMLPKTMNR--LTQLERLDLGSNEFTEV 199
>BC050445-1|AAH50445.1| 582|Homo sapiens soc-2 suppressor of clear
homolog (C. elegans) protein.
Length = 582
Score = 95.5 bits (227), Expect = 2e-19
Identities = 57/206 (27%), Positives = 101/206 (49%)
Frame = +2
Query: 149 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXP 328
+ L L ++ +P + + + L L +N ++ P P
Sbjct: 126 TELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIP 185
Query: 329 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGA 508
+ + L +L L L +N + + +I +L KL +K++P EIG+L L T
Sbjct: 186 SVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDV 245
Query: 509 RGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILK 688
N+L+ +P+E+ + ++ L L++N++ LPDT+ +++L LR NRL P S+ K
Sbjct: 246 AHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAK 305
Query: 689 CKELMFLQLNSNQISSVPANLDTSLV 766
C L L L +N IS++P +L +SLV
Sbjct: 306 CSALEELNLENNNISTLPESLLSSLV 331
Score = 83.8 bits (198), Expect = 7e-16
Identities = 65/246 (26%), Positives = 108/246 (43%), Gaps = 26/246 (10%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L ++ EIP ++Y + LYL N+I+ + P E
Sbjct: 174 LDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAE 233
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
IG L NL+ L++++N L L EIG+ ++ L ++P IG L+ L G R
Sbjct: 234 IGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRY 293
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTM-------DRMTALVHC----------- 640
N L IP + + L L LENN I TLP+++ + +T +C
Sbjct: 294 NRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQ 353
Query: 641 -------NLRNNRLEQFPSSIL-KCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRS 796
N+ +NR+ + P I + K L L + NQ++S+P LD + ++L +
Sbjct: 354 FSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLP--LDFGTWTSMVELNLAT 411
Query: 797 NPICEL 814
N + ++
Sbjct: 412 NQLTKI 417
Score = 81.4 bits (192), Expect = 4e-15
Identities = 51/164 (31%), Positives = 81/164 (49%), Gaps = 1/164 (0%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P + G ++V LNL+ N L + ++ L LE + LK++P +G L +L
Sbjct: 395 PLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELD 454
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
N+L+++P E+ L L+ L L NNQ+ TLP + +T L H L N L P I
Sbjct: 455 LEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIG 514
Query: 686 KCKELMFLQLNSN-QISSVPANLDTSLVPGLXMIDLRSNPICEL 814
+ L L LN N + S+P L +L L ++ + + P+ L
Sbjct: 515 TLENLEELYLNDNPNLHSLPFEL--ALCSKLSIMSIENCPLSHL 556
Score = 74.1 bits (174), Expect = 6e-13
Identities = 39/135 (28%), Positives = 69/135 (51%)
Frame = +2
Query: 347 KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELK 526
+N + L+LS +++L I +L +L + L+ +P E+G L L T N L
Sbjct: 100 ENSMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLT 159
Query: 527 TIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMF 706
++P+ + +L KLR L L +N++ +P + R+ +L LR NR+ I +L
Sbjct: 160 SLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSM 219
Query: 707 LQLNSNQISSVPANL 751
L + N+I +PA +
Sbjct: 220 LSIRENKIKQLPAEI 234
Score = 74.1 bits (174), Expect = 6e-13
Identities = 55/205 (26%), Positives = 86/205 (41%), Gaps = 4/205 (1%)
Frame = +2
Query: 149 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXP 328
SRL L ++ IP L C +E L L N IS P E
Sbjct: 287 SRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLP-ESLLSSLVKLNSLTLARNCFQL 345
Query: 329 TEIGN---LKNLVNLNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLD 496
+G + +LN+ +N +N + I K L L +P + G T +
Sbjct: 346 YPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMV 405
Query: 497 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 676
N+L IPE+++ L L L L NN ++ LP + + L +L N+LE P+
Sbjct: 406 ELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPN 465
Query: 677 SILKCKELMFLQLNSNQISSVPANL 751
I K+L L L +NQ++++P +
Sbjct: 466 EIAYLKDLQKLVLTNNQLTTLPRGI 490
Score = 62.9 bits (146), Expect = 1e-09
Identities = 47/201 (23%), Positives = 81/201 (40%), Gaps = 2/201 (0%)
Frame = +2
Query: 155 LSLNGFEITEIP-GLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
L++ I +IP G+ + L + N+++ P++ P
Sbjct: 360 LNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPE 419
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
++ L +L L LS N L L +G+L KL L+ +P EI L L
Sbjct: 420 DVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLT 479
Query: 512 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNN-RLEQFPSSILK 688
N+L T+P + L L L L N + LP+ + + L L +N L P +
Sbjct: 480 NNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNLHSLPFELAL 539
Query: 689 CKELMFLQLNSNQISSVPANL 751
C +L + + + +S +P +
Sbjct: 540 CSKLSIMSIENCPLSHLPPQI 560
>AL158163-2|CAH72812.1| 582|Homo sapiens soc-2 suppressor of clear
homolog (C. elegans) protein.
Length = 582
Score = 95.5 bits (227), Expect = 2e-19
Identities = 57/206 (27%), Positives = 101/206 (49%)
Frame = +2
Query: 149 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXP 328
+ L L ++ +P + + + L L +N ++ P P
Sbjct: 126 TELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIP 185
Query: 329 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGA 508
+ + L +L L L +N + + +I +L KL +K++P EIG+L L T
Sbjct: 186 SVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDV 245
Query: 509 RGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILK 688
N+L+ +P+E+ + ++ L L++N++ LPDT+ +++L LR NRL P S+ K
Sbjct: 246 AHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAK 305
Query: 689 CKELMFLQLNSNQISSVPANLDTSLV 766
C L L L +N IS++P +L +SLV
Sbjct: 306 CSALEELNLENNNISTLPESLLSSLV 331
Score = 83.8 bits (198), Expect = 7e-16
Identities = 65/246 (26%), Positives = 108/246 (43%), Gaps = 26/246 (10%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L ++ EIP ++Y + LYL N+I+ + P E
Sbjct: 174 LDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAE 233
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
IG L NL+ L++++N L L EIG+ ++ L ++P IG L+ L G R
Sbjct: 234 IGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRY 293
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTM-------DRMTALVHC----------- 640
N L IP + + L L LENN I TLP+++ + +T +C
Sbjct: 294 NRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQ 353
Query: 641 -------NLRNNRLEQFPSSIL-KCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRS 796
N+ +NR+ + P I + K L L + NQ++S+P LD + ++L +
Sbjct: 354 FSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLP--LDFGTWTSMVELNLAT 411
Query: 797 NPICEL 814
N + ++
Sbjct: 412 NQLTKI 417
Score = 81.4 bits (192), Expect = 4e-15
Identities = 51/164 (31%), Positives = 81/164 (49%), Gaps = 1/164 (0%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P + G ++V LNL+ N L + ++ L LE + LK++P +G L +L
Sbjct: 395 PLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELD 454
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
N+L+++P E+ L L+ L L NNQ+ TLP + +T L H L N L P I
Sbjct: 455 LEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIG 514
Query: 686 KCKELMFLQLNSN-QISSVPANLDTSLVPGLXMIDLRSNPICEL 814
+ L L LN N + S+P L +L L ++ + + P+ L
Sbjct: 515 TLENLEELYLNDNPNLHSLPFEL--ALCSKLSIMSIENCPLSHL 556
Score = 74.1 bits (174), Expect = 6e-13
Identities = 39/135 (28%), Positives = 69/135 (51%)
Frame = +2
Query: 347 KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELK 526
+N + L+LS +++L I +L +L + L+ +P E+G L L T N L
Sbjct: 100 ENSMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLT 159
Query: 527 TIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMF 706
++P+ + +L KLR L L +N++ +P + R+ +L LR NR+ I +L
Sbjct: 160 SLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSM 219
Query: 707 LQLNSNQISSVPANL 751
L + N+I +PA +
Sbjct: 220 LSIRENKIKQLPAEI 234
Score = 74.1 bits (174), Expect = 6e-13
Identities = 55/205 (26%), Positives = 86/205 (41%), Gaps = 4/205 (1%)
Frame = +2
Query: 149 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXP 328
SRL L ++ IP L C +E L L N IS P E
Sbjct: 287 SRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLP-ESLLSSLVKLNSLTLARNCFQL 345
Query: 329 TEIGN---LKNLVNLNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLD 496
+G + +LN+ +N +N + I K L L +P + G T +
Sbjct: 346 YPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMV 405
Query: 497 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 676
N+L IPE+++ L L L L NN ++ LP + + L +L N+LE P+
Sbjct: 406 ELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPN 465
Query: 677 SILKCKELMFLQLNSNQISSVPANL 751
I K+L L L +NQ++++P +
Sbjct: 466 EIAYLKDLQKLVLTNNQLTTLPRGI 490
Score = 62.9 bits (146), Expect = 1e-09
Identities = 47/201 (23%), Positives = 81/201 (40%), Gaps = 2/201 (0%)
Frame = +2
Query: 155 LSLNGFEITEIP-GLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
L++ I +IP G+ + L + N+++ P++ P
Sbjct: 360 LNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPE 419
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
++ L +L L LS N L L +G+L KL L+ +P EI L L
Sbjct: 420 DVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLT 479
Query: 512 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNN-RLEQFPSSILK 688
N+L T+P + L L L L N + LP+ + + L L +N L P +
Sbjct: 480 NNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNLHSLPFELAL 539
Query: 689 CKELMFLQLNSNQISSVPANL 751
C +L + + + +S +P +
Sbjct: 540 CSKLSIMSIENCPLSHLPPQI 560
>AF068920-1|AAC39856.1| 582|Homo sapiens Ras-binding protein SUR-8
protein.
Length = 582
Score = 95.5 bits (227), Expect = 2e-19
Identities = 57/206 (27%), Positives = 101/206 (49%)
Frame = +2
Query: 149 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXP 328
+ L L ++ +P + + + L L +N ++ P P
Sbjct: 126 TELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIP 185
Query: 329 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGA 508
+ + L +L L L +N + + +I +L KL +K++P EIG+L L T
Sbjct: 186 SVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDV 245
Query: 509 RGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILK 688
N+L+ +P+E+ + ++ L L++N++ LPDT+ +++L LR NRL P S+ K
Sbjct: 246 AHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAK 305
Query: 689 CKELMFLQLNSNQISSVPANLDTSLV 766
C L L L +N IS++P +L +SLV
Sbjct: 306 CSALEELNLENNNISTLPESLLSSLV 331
Score = 83.8 bits (198), Expect = 7e-16
Identities = 65/246 (26%), Positives = 108/246 (43%), Gaps = 26/246 (10%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L ++ EIP ++Y + LYL N+I+ + P E
Sbjct: 174 LDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAE 233
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
IG L NL+ L++++N L L EIG+ ++ L ++P IG L+ L G R
Sbjct: 234 IGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRY 293
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTM-------DRMTALVHC----------- 640
N L IP + + L L LENN I TLP+++ + +T +C
Sbjct: 294 NRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQ 353
Query: 641 -------NLRNNRLEQFPSSIL-KCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRS 796
N+ +NR+ + P I + K L L + NQ++S+P LD + ++L +
Sbjct: 354 FSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLP--LDFGTWTSMVELNLAT 411
Query: 797 NPICEL 814
N + ++
Sbjct: 412 NQLTKI 417
Score = 81.4 bits (192), Expect = 4e-15
Identities = 51/164 (31%), Positives = 81/164 (49%), Gaps = 1/164 (0%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P + G ++V LNL+ N L + ++ L LE + LK++P +G L +L
Sbjct: 395 PLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELD 454
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
N+L+++P E+ L L+ L L NNQ+ TLP + +T L H L N L P I
Sbjct: 455 LEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIG 514
Query: 686 KCKELMFLQLNSN-QISSVPANLDTSLVPGLXMIDLRSNPICEL 814
+ L L LN N + S+P L +L L ++ + + P+ L
Sbjct: 515 TLENLEELYLNDNPNLHSLPFEL--ALCSKLSIMSIENCPLSHL 556
Score = 74.1 bits (174), Expect = 6e-13
Identities = 39/135 (28%), Positives = 69/135 (51%)
Frame = +2
Query: 347 KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELK 526
+N + L+LS +++L I +L +L + L+ +P E+G L L T N L
Sbjct: 100 ENSMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLT 159
Query: 527 TIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMF 706
++P+ + +L KLR L L +N++ +P + R+ +L LR NR+ I +L
Sbjct: 160 SLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSM 219
Query: 707 LQLNSNQISSVPANL 751
L + N+I +PA +
Sbjct: 220 LSIRENKIKQLPAEI 234
Score = 74.1 bits (174), Expect = 6e-13
Identities = 55/205 (26%), Positives = 86/205 (41%), Gaps = 4/205 (1%)
Frame = +2
Query: 149 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXP 328
SRL L ++ IP L C +E L L N IS P E
Sbjct: 287 SRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLP-ESLLSSLVKLNSLTLARNCFQL 345
Query: 329 TEIGN---LKNLVNLNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLD 496
+G + +LN+ +N +N + I K L L +P + G T +
Sbjct: 346 YPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMV 405
Query: 497 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 676
N+L IPE+++ L L L L NN ++ LP + + L +L N+LE P+
Sbjct: 406 ELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPN 465
Query: 677 SILKCKELMFLQLNSNQISSVPANL 751
I K+L L L +NQ++++P +
Sbjct: 466 EIAYLKDLQKLVLTNNQLTTLPRGI 490
Score = 62.9 bits (146), Expect = 1e-09
Identities = 47/201 (23%), Positives = 81/201 (40%), Gaps = 2/201 (0%)
Frame = +2
Query: 155 LSLNGFEITEIP-GLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
L++ I +IP G+ + L + N+++ P++ P
Sbjct: 360 LNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPE 419
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
++ L +L L LS N L L +G+L KL L+ +P EI L L
Sbjct: 420 DVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLT 479
Query: 512 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNN-RLEQFPSSILK 688
N+L T+P + L L L L N + LP+ + + L L +N L P +
Sbjct: 480 NNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNLHSLPFELAL 539
Query: 689 CKELMFLQLNSNQISSVPANL 751
C +L + + + +S +P +
Sbjct: 540 CSKLSIMSIENCPLSHLPPQI 560
>AF054828-1|AAC25698.1| 582|Homo sapiens leucine-rich repeat
protein SHOC-2 protein.
Length = 582
Score = 95.5 bits (227), Expect = 2e-19
Identities = 57/206 (27%), Positives = 101/206 (49%)
Frame = +2
Query: 149 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXP 328
+ L L ++ +P + + + L L +N ++ P P
Sbjct: 126 TELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIP 185
Query: 329 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGA 508
+ + L +L L L +N + + +I +L KL +K++P EIG+L L T
Sbjct: 186 SVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDV 245
Query: 509 RGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILK 688
N+L+ +P+E+ + ++ L L++N++ LPDT+ +++L LR NRL P S+ K
Sbjct: 246 AHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAK 305
Query: 689 CKELMFLQLNSNQISSVPANLDTSLV 766
C L L L +N IS++P +L +SLV
Sbjct: 306 CSALEELNLENNNISTLPESLLSSLV 331
Score = 83.8 bits (198), Expect = 7e-16
Identities = 65/246 (26%), Positives = 108/246 (43%), Gaps = 26/246 (10%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L ++ EIP ++Y + LYL N+I+ + P E
Sbjct: 174 LDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAE 233
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
IG L NL+ L++++N L L EIG+ ++ L ++P IG L+ L G R
Sbjct: 234 IGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRY 293
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTM-------DRMTALVHC----------- 640
N L IP + + L L LENN I TLP+++ + +T +C
Sbjct: 294 NRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQ 353
Query: 641 -------NLRNNRLEQFPSSIL-KCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRS 796
N+ +NR+ + P I + K L L + NQ++S+P LD + ++L +
Sbjct: 354 FSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLP--LDFGTWTSMVELNLAT 411
Query: 797 NPICEL 814
N + ++
Sbjct: 412 NQLTKI 417
Score = 81.4 bits (192), Expect = 4e-15
Identities = 51/164 (31%), Positives = 81/164 (49%), Gaps = 1/164 (0%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P + G ++V LNL+ N L + ++ L LE + LK++P +G L +L
Sbjct: 395 PLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELD 454
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
N+L+++P E+ L L+ L L NNQ+ TLP + +T L H L N L P I
Sbjct: 455 LEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIG 514
Query: 686 KCKELMFLQLNSN-QISSVPANLDTSLVPGLXMIDLRSNPICEL 814
+ L L LN N + S+P L +L L ++ + + P+ L
Sbjct: 515 TLENLEELYLNDNPNLHSLPFEL--ALCSKLSIMSIENCPLSHL 556
Score = 74.1 bits (174), Expect = 6e-13
Identities = 39/135 (28%), Positives = 69/135 (51%)
Frame = +2
Query: 347 KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELK 526
+N + L+LS +++L I +L +L + L+ +P E+G L L T N L
Sbjct: 100 ENSMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLT 159
Query: 527 TIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMF 706
++P+ + +L KLR L L +N++ +P + R+ +L LR NR+ I +L
Sbjct: 160 SLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSM 219
Query: 707 LQLNSNQISSVPANL 751
L + N+I +PA +
Sbjct: 220 LSIRENKIKQLPAEI 234
Score = 74.1 bits (174), Expect = 6e-13
Identities = 55/205 (26%), Positives = 86/205 (41%), Gaps = 4/205 (1%)
Frame = +2
Query: 149 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXP 328
SRL L ++ IP L C +E L L N IS P E
Sbjct: 287 SRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLP-ESLLSSLVKLNSLTLARNCFQL 345
Query: 329 TEIGN---LKNLVNLNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLD 496
+G + +LN+ +N +N + I K L L +P + G T +
Sbjct: 346 YPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMV 405
Query: 497 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 676
N+L IPE+++ L L L L NN ++ LP + + L +L N+LE P+
Sbjct: 406 ELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPN 465
Query: 677 SILKCKELMFLQLNSNQISSVPANL 751
I K+L L L +NQ++++P +
Sbjct: 466 EIAYLKDLQKLVLTNNQLTTLPRGI 490
Score = 62.9 bits (146), Expect = 1e-09
Identities = 47/201 (23%), Positives = 81/201 (40%), Gaps = 2/201 (0%)
Frame = +2
Query: 155 LSLNGFEITEIP-GLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
L++ I +IP G+ + L + N+++ P++ P
Sbjct: 360 LNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPE 419
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
++ L +L L LS N L L +G+L KL L+ +P EI L L
Sbjct: 420 DVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLT 479
Query: 512 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNN-RLEQFPSSILK 688
N+L T+P + L L L L N + LP+ + + L L +N L P +
Sbjct: 480 NNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNLHSLPFELAL 539
Query: 689 CKELMFLQLNSNQISSVPANL 751
C +L + + + +S +P +
Sbjct: 540 CSKLSIMSIENCPLSHLPPQI 560
>AB020669-1|BAA74885.2| 584|Homo sapiens KIAA0862 protein protein.
Length = 584
Score = 95.5 bits (227), Expect = 2e-19
Identities = 57/206 (27%), Positives = 101/206 (49%)
Frame = +2
Query: 149 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXP 328
+ L L ++ +P + + + L L +N ++ P P
Sbjct: 128 TELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIP 187
Query: 329 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGA 508
+ + L +L L L +N + + +I +L KL +K++P EIG+L L T
Sbjct: 188 SVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDV 247
Query: 509 RGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILK 688
N+L+ +P+E+ + ++ L L++N++ LPDT+ +++L LR NRL P S+ K
Sbjct: 248 AHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAK 307
Query: 689 CKELMFLQLNSNQISSVPANLDTSLV 766
C L L L +N IS++P +L +SLV
Sbjct: 308 CSALEELNLENNNISTLPESLLSSLV 333
Score = 83.8 bits (198), Expect = 7e-16
Identities = 65/246 (26%), Positives = 108/246 (43%), Gaps = 26/246 (10%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L ++ EIP ++Y + LYL N+I+ + P E
Sbjct: 176 LDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAE 235
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
IG L NL+ L++++N L L EIG+ ++ L ++P IG L+ L G R
Sbjct: 236 IGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRY 295
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTM-------DRMTALVHC----------- 640
N L IP + + L L LENN I TLP+++ + +T +C
Sbjct: 296 NRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQ 355
Query: 641 -------NLRNNRLEQFPSSIL-KCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRS 796
N+ +NR+ + P I + K L L + NQ++S+P LD + ++L +
Sbjct: 356 FSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLP--LDFGTWTSMVELNLAT 413
Query: 797 NPICEL 814
N + ++
Sbjct: 414 NQLTKI 419
Score = 82.6 bits (195), Expect = 2e-15
Identities = 51/164 (31%), Positives = 82/164 (50%), Gaps = 1/164 (0%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P + G ++V LNL+ N L + ++ L LE + LK++P +G L +L
Sbjct: 397 PLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELD 456
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
N+L+++P E+ L L+ L L NNQ+ TLP + +T L H L N L P I
Sbjct: 457 LEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIG 516
Query: 686 KCKELMFLQLNSN-QISSVPANLDTSLVPGLXMIDLRSNPICEL 814
+ L L LN N + S+P L+ +L L ++ + + P+ L
Sbjct: 517 TLENLEELYLNDNPNLHSLP--LELALCSKLSIMSIENCPLSHL 558
Score = 74.1 bits (174), Expect = 6e-13
Identities = 39/135 (28%), Positives = 69/135 (51%)
Frame = +2
Query: 347 KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELK 526
+N + L+LS +++L I +L +L + L+ +P E+G L L T N L
Sbjct: 102 ENSMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLT 161
Query: 527 TIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMF 706
++P+ + +L KLR L L +N++ +P + R+ +L LR NR+ I +L
Sbjct: 162 SLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSM 221
Query: 707 LQLNSNQISSVPANL 751
L + N+I +PA +
Sbjct: 222 LSIRENKIKQLPAEI 236
Score = 74.1 bits (174), Expect = 6e-13
Identities = 55/205 (26%), Positives = 86/205 (41%), Gaps = 4/205 (1%)
Frame = +2
Query: 149 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXP 328
SRL L ++ IP L C +E L L N IS P E
Sbjct: 289 SRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLP-ESLLSSLVKLNSLTLARNCFQL 347
Query: 329 TEIGN---LKNLVNLNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLD 496
+G + +LN+ +N +N + I K L L +P + G T +
Sbjct: 348 YPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMV 407
Query: 497 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 676
N+L IPE+++ L L L L NN ++ LP + + L +L N+LE P+
Sbjct: 408 ELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPN 467
Query: 677 SILKCKELMFLQLNSNQISSVPANL 751
I K+L L L +NQ++++P +
Sbjct: 468 EIAYLKDLQKLVLTNNQLTTLPRGI 492
Score = 62.9 bits (146), Expect = 1e-09
Identities = 47/201 (23%), Positives = 81/201 (40%), Gaps = 2/201 (0%)
Frame = +2
Query: 155 LSLNGFEITEIP-GLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
L++ I +IP G+ + L + N+++ P++ P
Sbjct: 362 LNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPE 421
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
++ L +L L LS N L L +G+L KL L+ +P EI L L
Sbjct: 422 DVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLT 481
Query: 512 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNN-RLEQFPSSILK 688
N+L T+P + L L L L N + LP+ + + L L +N L P +
Sbjct: 482 NNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNLHSLPLELAL 541
Query: 689 CKELMFLQLNSNQISSVPANL 751
C +L + + + +S +P +
Sbjct: 542 CSKLSIMSIENCPLSHLPPQI 562
>AL391728-2|CAH73692.1| 1495|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1495
Score = 94.7 bits (225), Expect = 4e-19
Identities = 65/220 (29%), Positives = 101/220 (45%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ +I E+P L+ C + L + N +S P P
Sbjct: 56 LYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPEN 115
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
I K L + S NP++ L L L + N L+ +P G+L +L R
Sbjct: 116 IKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRE 175
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N LKT+P+ M LA+L L L NN+ LP+ +D++ L + NN L+ P SI K K
Sbjct: 176 NHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLK 235
Query: 695 ELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
L++L ++ N+I +V ++D S L + L SN + +L
Sbjct: 236 MLVYLDMSKNRIETV--DMDISGCEALEDLLLSSNMLQQL 273
Score = 89.8 bits (213), Expect = 1e-17
Identities = 57/181 (31%), Positives = 85/181 (46%)
Frame = +2
Query: 185 IPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNL 364
+PG + + +L + KN+I ++ P IG LK L L
Sbjct: 227 LPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTL 286
Query: 365 NLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEM 544
+ N L +L IG+L LE F C+ L+ +P IG L L T N L +P E+
Sbjct: 287 KVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREI 346
Query: 545 TSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 724
S + ++L +N++E LP+ + +M L NL +NRL+ P S K KEL L L+ N
Sbjct: 347 GSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDN 406
Query: 725 Q 727
Q
Sbjct: 407 Q 407
Score = 85.0 bits (201), Expect = 3e-16
Identities = 52/200 (26%), Positives = 90/200 (45%)
Frame = +2
Query: 152 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
+LS+ +++ +P + + + ++ L + KN + FP P
Sbjct: 78 KLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPD 137
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
L NL L L+ L L G L KL LK +PK + KL QL+
Sbjct: 138 GFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLG 197
Query: 512 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 691
NE +PE + + LR L ++NN ++ LP ++ ++ LV+ ++ NR+E I C
Sbjct: 198 NNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGC 257
Query: 692 KELMFLQLNSNQISSVPANL 751
+ L L L+SN + +P ++
Sbjct: 258 EALEDLLLSSNMLQQLPDSI 277
Score = 75.8 bits (178), Expect = 2e-13
Identities = 50/199 (25%), Positives = 86/199 (43%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L + +P ++ ++E L L N+ P P
Sbjct: 171 LELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGS 230
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
IG LK LV L++S N + + +I E LE + L+++P IG L +L T
Sbjct: 231 IGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDD 290
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N+L +P + +L+ L N++E+LP T+ + +L + N L + P I CK
Sbjct: 291 NQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCK 350
Query: 695 ELMFLQLNSNQISSVPANL 751
+ + L SN++ +P +
Sbjct: 351 NVTVMSLRSNKLEFLPEEI 369
Score = 51.2 bits (117), Expect = 4e-06
Identities = 38/157 (24%), Positives = 69/157 (43%), Gaps = 1/157 (0%)
Frame = +2
Query: 362 LNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE 538
L+ S+ L + E+ + E+ LE + + ++E+PK++ L N+L +P
Sbjct: 32 LDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPT 91
Query: 539 EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLN 718
+ SL L+ L + N ++ P+ + L N + + P + L L LN
Sbjct: 92 TIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLN 151
Query: 719 SNQISSVPANLDTSLVPGLXMIDLRSNPICELSHPEH 829
+ +PAN LV L +++LR N + L H
Sbjct: 152 DAFLEFLPANFG-RLVK-LRILELRENHLKTLPKSMH 186
Score = 48.0 bits (109), Expect = 4e-05
Identities = 39/164 (23%), Positives = 67/164 (40%), Gaps = 1/164 (0%)
Frame = +2
Query: 326 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
P E+ N + L L L N + L ++ + + L L +P I L L
Sbjct: 43 PKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKEL 102
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 682
N ++ PE + L + N I LPD ++ L L + LE P++
Sbjct: 103 DISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANF 162
Query: 683 LKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
+ +L L+L N + ++P ++ + L +DL +N EL
Sbjct: 163 GRLVKLRILELRENHLKTLPKSMHK--LAQLERLDLGNNEFGEL 204
Score = 47.6 bits (108), Expect = 6e-05
Identities = 36/149 (24%), Positives = 63/149 (42%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ + ++P + ++ L + N++++ P P+
Sbjct: 263 LLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPST 322
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
IG L +L L + N L L EIG + + L+ +P+EIG++ +L
Sbjct: 323 IGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSD 382
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETL 601
N LK +P T L +L L L +NQ + L
Sbjct: 383 NRLKNLPFSFTKLKELAALWLSDNQSKAL 411
>AL391728-1|CAH73691.1| 1537|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1537
Score = 94.7 bits (225), Expect = 4e-19
Identities = 65/220 (29%), Positives = 101/220 (45%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ +I E+P L+ C + L + N +S P P
Sbjct: 51 LYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPEN 110
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
I K L + S NP++ L L L + N L+ +P G+L +L R
Sbjct: 111 IKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRE 170
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N LKT+P+ M LA+L L L NN+ LP+ +D++ L + NN L+ P SI K K
Sbjct: 171 NHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLK 230
Query: 695 ELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
L++L ++ N+I +V ++D S L + L SN + +L
Sbjct: 231 MLVYLDMSKNRIETV--DMDISGCEALEDLLLSSNMLQQL 268
Score = 89.8 bits (213), Expect = 1e-17
Identities = 57/181 (31%), Positives = 85/181 (46%)
Frame = +2
Query: 185 IPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNL 364
+PG + + +L + KN+I ++ P IG LK L L
Sbjct: 222 LPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTL 281
Query: 365 NLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEM 544
+ N L +L IG+L LE F C+ L+ +P IG L L T N L +P E+
Sbjct: 282 KVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREI 341
Query: 545 TSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 724
S + ++L +N++E LP+ + +M L NL +NRL+ P S K KEL L L+ N
Sbjct: 342 GSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDN 401
Query: 725 Q 727
Q
Sbjct: 402 Q 402
Score = 85.0 bits (201), Expect = 3e-16
Identities = 52/200 (26%), Positives = 90/200 (45%)
Frame = +2
Query: 152 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
+LS+ +++ +P + + + ++ L + KN + FP P
Sbjct: 73 KLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPD 132
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
L NL L L+ L L G L KL LK +PK + KL QL+
Sbjct: 133 GFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLG 192
Query: 512 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 691
NE +PE + + LR L ++NN ++ LP ++ ++ LV+ ++ NR+E I C
Sbjct: 193 NNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGC 252
Query: 692 KELMFLQLNSNQISSVPANL 751
+ L L L+SN + +P ++
Sbjct: 253 EALEDLLLSSNMLQQLPDSI 272
Score = 75.8 bits (178), Expect = 2e-13
Identities = 50/199 (25%), Positives = 86/199 (43%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L + +P ++ ++E L L N+ P P
Sbjct: 166 LELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGS 225
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
IG LK LV L++S N + + +I E LE + L+++P IG L +L T
Sbjct: 226 IGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDD 285
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N+L +P + +L+ L N++E+LP T+ + +L + N L + P I CK
Sbjct: 286 NQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCK 345
Query: 695 ELMFLQLNSNQISSVPANL 751
+ + L SN++ +P +
Sbjct: 346 NVTVMSLRSNKLEFLPEEI 364
Score = 51.2 bits (117), Expect = 4e-06
Identities = 38/157 (24%), Positives = 69/157 (43%), Gaps = 1/157 (0%)
Frame = +2
Query: 362 LNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE 538
L+ S+ L + E+ + E+ LE + + ++E+PK++ L N+L +P
Sbjct: 27 LDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPT 86
Query: 539 EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLN 718
+ SL L+ L + N ++ P+ + L N + + P + L L LN
Sbjct: 87 TIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLN 146
Query: 719 SNQISSVPANLDTSLVPGLXMIDLRSNPICELSHPEH 829
+ +PAN LV L +++LR N + L H
Sbjct: 147 DAFLEFLPANFG-RLVK-LRILELRENHLKTLPKSMH 181
Score = 48.0 bits (109), Expect = 4e-05
Identities = 39/164 (23%), Positives = 67/164 (40%), Gaps = 1/164 (0%)
Frame = +2
Query: 326 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
P E+ N + L L L N + L ++ + + L L +P I L L
Sbjct: 38 PKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKEL 97
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 682
N ++ PE + L + N I LPD ++ L L + LE P++
Sbjct: 98 DISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANF 157
Query: 683 LKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
+ +L L+L N + ++P ++ + L +DL +N EL
Sbjct: 158 GRLVKLRILELRENHLKTLPKSMHK--LAQLERLDLGNNEFGEL 199
Score = 47.6 bits (108), Expect = 6e-05
Identities = 36/149 (24%), Positives = 63/149 (42%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ + ++P + ++ L + N++++ P P+
Sbjct: 258 LLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPST 317
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
IG L +L L + N L L EIG + + L+ +P+EIG++ +L
Sbjct: 318 IGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSD 377
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETL 601
N LK +P T L +L L L +NQ + L
Sbjct: 378 NRLKNLPFSFTKLKELAALWLSDNQSKAL 406
>AL359412-2|CAH74019.1| 1495|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1495
Score = 94.7 bits (225), Expect = 4e-19
Identities = 65/220 (29%), Positives = 101/220 (45%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ +I E+P L+ C + L + N +S P P
Sbjct: 56 LYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPEN 115
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
I K L + S NP++ L L L + N L+ +P G+L +L R
Sbjct: 116 IKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRE 175
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N LKT+P+ M LA+L L L NN+ LP+ +D++ L + NN L+ P SI K K
Sbjct: 176 NHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLK 235
Query: 695 ELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
L++L ++ N+I +V ++D S L + L SN + +L
Sbjct: 236 MLVYLDMSKNRIETV--DMDISGCEALEDLLLSSNMLQQL 273
Score = 89.8 bits (213), Expect = 1e-17
Identities = 57/181 (31%), Positives = 85/181 (46%)
Frame = +2
Query: 185 IPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNL 364
+PG + + +L + KN+I ++ P IG LK L L
Sbjct: 227 LPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTL 286
Query: 365 NLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEM 544
+ N L +L IG+L LE F C+ L+ +P IG L L T N L +P E+
Sbjct: 287 KVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREI 346
Query: 545 TSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 724
S + ++L +N++E LP+ + +M L NL +NRL+ P S K KEL L L+ N
Sbjct: 347 GSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDN 406
Query: 725 Q 727
Q
Sbjct: 407 Q 407
Score = 85.0 bits (201), Expect = 3e-16
Identities = 52/200 (26%), Positives = 90/200 (45%)
Frame = +2
Query: 152 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
+LS+ +++ +P + + + ++ L + KN + FP P
Sbjct: 78 KLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPD 137
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
L NL L L+ L L G L KL LK +PK + KL QL+
Sbjct: 138 GFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLG 197
Query: 512 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 691
NE +PE + + LR L ++NN ++ LP ++ ++ LV+ ++ NR+E I C
Sbjct: 198 NNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGC 257
Query: 692 KELMFLQLNSNQISSVPANL 751
+ L L L+SN + +P ++
Sbjct: 258 EALEDLLLSSNMLQQLPDSI 277
Score = 75.8 bits (178), Expect = 2e-13
Identities = 50/199 (25%), Positives = 86/199 (43%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L + +P ++ ++E L L N+ P P
Sbjct: 171 LELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGS 230
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
IG LK LV L++S N + + +I E LE + L+++P IG L +L T
Sbjct: 231 IGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDD 290
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N+L +P + +L+ L N++E+LP T+ + +L + N L + P I CK
Sbjct: 291 NQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCK 350
Query: 695 ELMFLQLNSNQISSVPANL 751
+ + L SN++ +P +
Sbjct: 351 NVTVMSLRSNKLEFLPEEI 369
Score = 51.2 bits (117), Expect = 4e-06
Identities = 38/157 (24%), Positives = 69/157 (43%), Gaps = 1/157 (0%)
Frame = +2
Query: 362 LNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE 538
L+ S+ L + E+ + E+ LE + + ++E+PK++ L N+L +P
Sbjct: 32 LDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPT 91
Query: 539 EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLN 718
+ SL L+ L + N ++ P+ + L N + + P + L L LN
Sbjct: 92 TIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLN 151
Query: 719 SNQISSVPANLDTSLVPGLXMIDLRSNPICELSHPEH 829
+ +PAN LV L +++LR N + L H
Sbjct: 152 DAFLEFLPANFG-RLVK-LRILELRENHLKTLPKSMH 186
Score = 48.0 bits (109), Expect = 4e-05
Identities = 39/164 (23%), Positives = 67/164 (40%), Gaps = 1/164 (0%)
Frame = +2
Query: 326 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
P E+ N + L L L N + L ++ + + L L +P I L L
Sbjct: 43 PKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKEL 102
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 682
N ++ PE + L + N I LPD ++ L L + LE P++
Sbjct: 103 DISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANF 162
Query: 683 LKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
+ +L L+L N + ++P ++ + L +DL +N EL
Sbjct: 163 GRLVKLRILELRENHLKTLPKSMHK--LAQLERLDLGNNEFGEL 204
Score = 47.6 bits (108), Expect = 6e-05
Identities = 36/149 (24%), Positives = 63/149 (42%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ + ++P + ++ L + N++++ P P+
Sbjct: 263 LLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPST 322
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
IG L +L L + N L L EIG + + L+ +P+EIG++ +L
Sbjct: 323 IGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSD 382
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETL 601
N LK +P T L +L L L +NQ + L
Sbjct: 383 NRLKNLPFSFTKLKELAALWLSDNQSKAL 411
>AL359412-1|CAH74018.1| 1537|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1537
Score = 94.7 bits (225), Expect = 4e-19
Identities = 65/220 (29%), Positives = 101/220 (45%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ +I E+P L+ C + L + N +S P P
Sbjct: 51 LYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPEN 110
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
I K L + S NP++ L L L + N L+ +P G+L +L R
Sbjct: 111 IKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRE 170
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N LKT+P+ M LA+L L L NN+ LP+ +D++ L + NN L+ P SI K K
Sbjct: 171 NHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLK 230
Query: 695 ELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
L++L ++ N+I +V ++D S L + L SN + +L
Sbjct: 231 MLVYLDMSKNRIETV--DMDISGCEALEDLLLSSNMLQQL 268
Score = 89.8 bits (213), Expect = 1e-17
Identities = 57/181 (31%), Positives = 85/181 (46%)
Frame = +2
Query: 185 IPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNL 364
+PG + + +L + KN+I ++ P IG LK L L
Sbjct: 222 LPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTL 281
Query: 365 NLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEM 544
+ N L +L IG+L LE F C+ L+ +P IG L L T N L +P E+
Sbjct: 282 KVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREI 341
Query: 545 TSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 724
S + ++L +N++E LP+ + +M L NL +NRL+ P S K KEL L L+ N
Sbjct: 342 GSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDN 401
Query: 725 Q 727
Q
Sbjct: 402 Q 402
Score = 85.0 bits (201), Expect = 3e-16
Identities = 52/200 (26%), Positives = 90/200 (45%)
Frame = +2
Query: 152 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
+LS+ +++ +P + + + ++ L + KN + FP P
Sbjct: 73 KLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPD 132
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
L NL L L+ L L G L KL LK +PK + KL QL+
Sbjct: 133 GFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLG 192
Query: 512 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 691
NE +PE + + LR L ++NN ++ LP ++ ++ LV+ ++ NR+E I C
Sbjct: 193 NNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGC 252
Query: 692 KELMFLQLNSNQISSVPANL 751
+ L L L+SN + +P ++
Sbjct: 253 EALEDLLLSSNMLQQLPDSI 272
Score = 75.8 bits (178), Expect = 2e-13
Identities = 50/199 (25%), Positives = 86/199 (43%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L + +P ++ ++E L L N+ P P
Sbjct: 166 LELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGS 225
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
IG LK LV L++S N + + +I E LE + L+++P IG L +L T
Sbjct: 226 IGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDD 285
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N+L +P + +L+ L N++E+LP T+ + +L + N L + P I CK
Sbjct: 286 NQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCK 345
Query: 695 ELMFLQLNSNQISSVPANL 751
+ + L SN++ +P +
Sbjct: 346 NVTVMSLRSNKLEFLPEEI 364
Score = 51.2 bits (117), Expect = 4e-06
Identities = 38/157 (24%), Positives = 69/157 (43%), Gaps = 1/157 (0%)
Frame = +2
Query: 362 LNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE 538
L+ S+ L + E+ + E+ LE + + ++E+PK++ L N+L +P
Sbjct: 27 LDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPT 86
Query: 539 EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLN 718
+ SL L+ L + N ++ P+ + L N + + P + L L LN
Sbjct: 87 TIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLN 146
Query: 719 SNQISSVPANLDTSLVPGLXMIDLRSNPICELSHPEH 829
+ +PAN LV L +++LR N + L H
Sbjct: 147 DAFLEFLPANFG-RLVK-LRILELRENHLKTLPKSMH 181
Score = 48.0 bits (109), Expect = 4e-05
Identities = 39/164 (23%), Positives = 67/164 (40%), Gaps = 1/164 (0%)
Frame = +2
Query: 326 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
P E+ N + L L L N + L ++ + + L L +P I L L
Sbjct: 38 PKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKEL 97
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 682
N ++ PE + L + N I LPD ++ L L + LE P++
Sbjct: 98 DISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANF 157
Query: 683 LKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
+ +L L+L N + ++P ++ + L +DL +N EL
Sbjct: 158 GRLVKLRILELRENHLKTLPKSMHK--LAQLERLDLGNNEFGEL 199
Score = 47.6 bits (108), Expect = 6e-05
Identities = 36/149 (24%), Positives = 63/149 (42%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ + ++P + ++ L + N++++ P P+
Sbjct: 258 LLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPST 317
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
IG L +L L + N L L EIG + + L+ +P+EIG++ +L
Sbjct: 318 IGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSD 377
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETL 601
N LK +P T L +L L L +NQ + L
Sbjct: 378 NRLKNLPFSFTKLKELAALWLSDNQSKAL 406
>AL158840-2|CAH70975.1| 1495|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1495
Score = 94.7 bits (225), Expect = 4e-19
Identities = 65/220 (29%), Positives = 101/220 (45%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ +I E+P L+ C + L + N +S P P
Sbjct: 56 LYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPEN 115
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
I K L + S NP++ L L L + N L+ +P G+L +L R
Sbjct: 116 IKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRE 175
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N LKT+P+ M LA+L L L NN+ LP+ +D++ L + NN L+ P SI K K
Sbjct: 176 NHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLK 235
Query: 695 ELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
L++L ++ N+I +V ++D S L + L SN + +L
Sbjct: 236 MLVYLDMSKNRIETV--DMDISGCEALEDLLLSSNMLQQL 273
Score = 89.8 bits (213), Expect = 1e-17
Identities = 57/181 (31%), Positives = 85/181 (46%)
Frame = +2
Query: 185 IPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNL 364
+PG + + +L + KN+I ++ P IG LK L L
Sbjct: 227 LPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTL 286
Query: 365 NLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEM 544
+ N L +L IG+L LE F C+ L+ +P IG L L T N L +P E+
Sbjct: 287 KVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREI 346
Query: 545 TSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 724
S + ++L +N++E LP+ + +M L NL +NRL+ P S K KEL L L+ N
Sbjct: 347 GSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDN 406
Query: 725 Q 727
Q
Sbjct: 407 Q 407
Score = 85.0 bits (201), Expect = 3e-16
Identities = 52/200 (26%), Positives = 90/200 (45%)
Frame = +2
Query: 152 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
+LS+ +++ +P + + + ++ L + KN + FP P
Sbjct: 78 KLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPD 137
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
L NL L L+ L L G L KL LK +PK + KL QL+
Sbjct: 138 GFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLG 197
Query: 512 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 691
NE +PE + + LR L ++NN ++ LP ++ ++ LV+ ++ NR+E I C
Sbjct: 198 NNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGC 257
Query: 692 KELMFLQLNSNQISSVPANL 751
+ L L L+SN + +P ++
Sbjct: 258 EALEDLLLSSNMLQQLPDSI 277
Score = 75.8 bits (178), Expect = 2e-13
Identities = 50/199 (25%), Positives = 86/199 (43%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L + +P ++ ++E L L N+ P P
Sbjct: 171 LELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGS 230
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
IG LK LV L++S N + + +I E LE + L+++P IG L +L T
Sbjct: 231 IGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDD 290
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N+L +P + +L+ L N++E+LP T+ + +L + N L + P I CK
Sbjct: 291 NQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCK 350
Query: 695 ELMFLQLNSNQISSVPANL 751
+ + L SN++ +P +
Sbjct: 351 NVTVMSLRSNKLEFLPEEI 369
Score = 51.2 bits (117), Expect = 4e-06
Identities = 38/157 (24%), Positives = 69/157 (43%), Gaps = 1/157 (0%)
Frame = +2
Query: 362 LNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE 538
L+ S+ L + E+ + E+ LE + + ++E+PK++ L N+L +P
Sbjct: 32 LDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPT 91
Query: 539 EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLN 718
+ SL L+ L + N ++ P+ + L N + + P + L L LN
Sbjct: 92 TIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLN 151
Query: 719 SNQISSVPANLDTSLVPGLXMIDLRSNPICELSHPEH 829
+ +PAN LV L +++LR N + L H
Sbjct: 152 DAFLEFLPANFG-RLVK-LRILELRENHLKTLPKSMH 186
Score = 48.0 bits (109), Expect = 4e-05
Identities = 39/164 (23%), Positives = 67/164 (40%), Gaps = 1/164 (0%)
Frame = +2
Query: 326 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
P E+ N + L L L N + L ++ + + L L +P I L L
Sbjct: 43 PKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKEL 102
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 682
N ++ PE + L + N I LPD ++ L L + LE P++
Sbjct: 103 DISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANF 162
Query: 683 LKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
+ +L L+L N + ++P ++ + L +DL +N EL
Sbjct: 163 GRLVKLRILELRENHLKTLPKSMHK--LAQLERLDLGNNEFGEL 204
Score = 47.6 bits (108), Expect = 6e-05
Identities = 36/149 (24%), Positives = 63/149 (42%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ + ++P + ++ L + N++++ P P+
Sbjct: 263 LLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPST 322
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
IG L +L L + N L L EIG + + L+ +P+EIG++ +L
Sbjct: 323 IGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSD 382
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETL 601
N LK +P T L +L L L +NQ + L
Sbjct: 383 NRLKNLPFSFTKLKELAALWLSDNQSKAL 411
>AL158840-1|CAH70974.1| 1537|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1537
Score = 94.7 bits (225), Expect = 4e-19
Identities = 65/220 (29%), Positives = 101/220 (45%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ +I E+P L+ C + L + N +S P P
Sbjct: 51 LYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPEN 110
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
I K L + S NP++ L L L + N L+ +P G+L +L R
Sbjct: 111 IKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRE 170
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N LKT+P+ M LA+L L L NN+ LP+ +D++ L + NN L+ P SI K K
Sbjct: 171 NHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLK 230
Query: 695 ELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
L++L ++ N+I +V ++D S L + L SN + +L
Sbjct: 231 MLVYLDMSKNRIETV--DMDISGCEALEDLLLSSNMLQQL 268
Score = 89.8 bits (213), Expect = 1e-17
Identities = 57/181 (31%), Positives = 85/181 (46%)
Frame = +2
Query: 185 IPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNL 364
+PG + + +L + KN+I ++ P IG LK L L
Sbjct: 222 LPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTL 281
Query: 365 NLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEM 544
+ N L +L IG+L LE F C+ L+ +P IG L L T N L +P E+
Sbjct: 282 KVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREI 341
Query: 545 TSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 724
S + ++L +N++E LP+ + +M L NL +NRL+ P S K KEL L L+ N
Sbjct: 342 GSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDN 401
Query: 725 Q 727
Q
Sbjct: 402 Q 402
Score = 85.0 bits (201), Expect = 3e-16
Identities = 52/200 (26%), Positives = 90/200 (45%)
Frame = +2
Query: 152 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
+LS+ +++ +P + + + ++ L + KN + FP P
Sbjct: 73 KLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPD 132
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
L NL L L+ L L G L KL LK +PK + KL QL+
Sbjct: 133 GFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLG 192
Query: 512 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 691
NE +PE + + LR L ++NN ++ LP ++ ++ LV+ ++ NR+E I C
Sbjct: 193 NNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGC 252
Query: 692 KELMFLQLNSNQISSVPANL 751
+ L L L+SN + +P ++
Sbjct: 253 EALEDLLLSSNMLQQLPDSI 272
Score = 75.8 bits (178), Expect = 2e-13
Identities = 50/199 (25%), Positives = 86/199 (43%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L + +P ++ ++E L L N+ P P
Sbjct: 166 LELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGS 225
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
IG LK LV L++S N + + +I E LE + L+++P IG L +L T
Sbjct: 226 IGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDD 285
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N+L +P + +L+ L N++E+LP T+ + +L + N L + P I CK
Sbjct: 286 NQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCK 345
Query: 695 ELMFLQLNSNQISSVPANL 751
+ + L SN++ +P +
Sbjct: 346 NVTVMSLRSNKLEFLPEEI 364
Score = 51.2 bits (117), Expect = 4e-06
Identities = 38/157 (24%), Positives = 69/157 (43%), Gaps = 1/157 (0%)
Frame = +2
Query: 362 LNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE 538
L+ S+ L + E+ + E+ LE + + ++E+PK++ L N+L +P
Sbjct: 27 LDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPT 86
Query: 539 EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLN 718
+ SL L+ L + N ++ P+ + L N + + P + L L LN
Sbjct: 87 TIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLN 146
Query: 719 SNQISSVPANLDTSLVPGLXMIDLRSNPICELSHPEH 829
+ +PAN LV L +++LR N + L H
Sbjct: 147 DAFLEFLPANFG-RLVK-LRILELRENHLKTLPKSMH 181
Score = 48.0 bits (109), Expect = 4e-05
Identities = 39/164 (23%), Positives = 67/164 (40%), Gaps = 1/164 (0%)
Frame = +2
Query: 326 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
P E+ N + L L L N + L ++ + + L L +P I L L
Sbjct: 38 PKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKEL 97
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 682
N ++ PE + L + N I LPD ++ L L + LE P++
Sbjct: 98 DISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANF 157
Query: 683 LKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
+ +L L+L N + ++P ++ + L +DL +N EL
Sbjct: 158 GRLVKLRILELRENHLKTLPKSMHK--LAQLERLDLGNNEFGEL 199
Score = 47.6 bits (108), Expect = 6e-05
Identities = 36/149 (24%), Positives = 63/149 (42%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ + ++P + ++ L + N++++ P P+
Sbjct: 258 LLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPST 317
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
IG L +L L + N L L EIG + + L+ +P+EIG++ +L
Sbjct: 318 IGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSD 377
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETL 601
N LK +P T L +L L L +NQ + L
Sbjct: 378 NRLKNLPFSFTKLKELAALWLSDNQSKAL 406
>AL157948-2|CAI22426.1| 1495|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1495
Score = 94.7 bits (225), Expect = 4e-19
Identities = 65/220 (29%), Positives = 101/220 (45%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ +I E+P L+ C + L + N +S P P
Sbjct: 56 LYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPEN 115
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
I K L + S NP++ L L L + N L+ +P G+L +L R
Sbjct: 116 IKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRE 175
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N LKT+P+ M LA+L L L NN+ LP+ +D++ L + NN L+ P SI K K
Sbjct: 176 NHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLK 235
Query: 695 ELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
L++L ++ N+I +V ++D S L + L SN + +L
Sbjct: 236 MLVYLDMSKNRIETV--DMDISGCEALEDLLLSSNMLQQL 273
Score = 89.8 bits (213), Expect = 1e-17
Identities = 57/181 (31%), Positives = 85/181 (46%)
Frame = +2
Query: 185 IPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNL 364
+PG + + +L + KN+I ++ P IG LK L L
Sbjct: 227 LPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTL 286
Query: 365 NLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEM 544
+ N L +L IG+L LE F C+ L+ +P IG L L T N L +P E+
Sbjct: 287 KVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREI 346
Query: 545 TSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 724
S + ++L +N++E LP+ + +M L NL +NRL+ P S K KEL L L+ N
Sbjct: 347 GSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDN 406
Query: 725 Q 727
Q
Sbjct: 407 Q 407
Score = 85.0 bits (201), Expect = 3e-16
Identities = 52/200 (26%), Positives = 90/200 (45%)
Frame = +2
Query: 152 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
+LS+ +++ +P + + + ++ L + KN + FP P
Sbjct: 78 KLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPD 137
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
L NL L L+ L L G L KL LK +PK + KL QL+
Sbjct: 138 GFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLG 197
Query: 512 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 691
NE +PE + + LR L ++NN ++ LP ++ ++ LV+ ++ NR+E I C
Sbjct: 198 NNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGC 257
Query: 692 KELMFLQLNSNQISSVPANL 751
+ L L L+SN + +P ++
Sbjct: 258 EALEDLLLSSNMLQQLPDSI 277
Score = 75.8 bits (178), Expect = 2e-13
Identities = 50/199 (25%), Positives = 86/199 (43%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L + +P ++ ++E L L N+ P P
Sbjct: 171 LELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGS 230
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
IG LK LV L++S N + + +I E LE + L+++P IG L +L T
Sbjct: 231 IGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDD 290
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N+L +P + +L+ L N++E+LP T+ + +L + N L + P I CK
Sbjct: 291 NQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCK 350
Query: 695 ELMFLQLNSNQISSVPANL 751
+ + L SN++ +P +
Sbjct: 351 NVTVMSLRSNKLEFLPEEI 369
Score = 51.2 bits (117), Expect = 4e-06
Identities = 38/157 (24%), Positives = 69/157 (43%), Gaps = 1/157 (0%)
Frame = +2
Query: 362 LNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE 538
L+ S+ L + E+ + E+ LE + + ++E+PK++ L N+L +P
Sbjct: 32 LDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPT 91
Query: 539 EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLN 718
+ SL L+ L + N ++ P+ + L N + + P + L L LN
Sbjct: 92 TIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLN 151
Query: 719 SNQISSVPANLDTSLVPGLXMIDLRSNPICELSHPEH 829
+ +PAN LV L +++LR N + L H
Sbjct: 152 DAFLEFLPANFG-RLVK-LRILELRENHLKTLPKSMH 186
Score = 48.0 bits (109), Expect = 4e-05
Identities = 39/164 (23%), Positives = 67/164 (40%), Gaps = 1/164 (0%)
Frame = +2
Query: 326 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
P E+ N + L L L N + L ++ + + L L +P I L L
Sbjct: 43 PKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKEL 102
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 682
N ++ PE + L + N I LPD ++ L L + LE P++
Sbjct: 103 DISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANF 162
Query: 683 LKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
+ +L L+L N + ++P ++ + L +DL +N EL
Sbjct: 163 GRLVKLRILELRENHLKTLPKSMHK--LAQLERLDLGNNEFGEL 204
Score = 47.6 bits (108), Expect = 6e-05
Identities = 36/149 (24%), Positives = 63/149 (42%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ + ++P + ++ L + N++++ P P+
Sbjct: 263 LLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPST 322
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
IG L +L L + N L L EIG + + L+ +P+EIG++ +L
Sbjct: 323 IGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSD 382
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETL 601
N LK +P T L +L L L +NQ + L
Sbjct: 383 NRLKNLPFSFTKLKELAALWLSDNQSKAL 411
>AL157948-1|CAI22425.1| 1537|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1537
Score = 94.7 bits (225), Expect = 4e-19
Identities = 65/220 (29%), Positives = 101/220 (45%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ +I E+P L+ C + L + N +S P P
Sbjct: 51 LYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPEN 110
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
I K L + S NP++ L L L + N L+ +P G+L +L R
Sbjct: 111 IKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRE 170
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N LKT+P+ M LA+L L L NN+ LP+ +D++ L + NN L+ P SI K K
Sbjct: 171 NHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLK 230
Query: 695 ELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
L++L ++ N+I +V ++D S L + L SN + +L
Sbjct: 231 MLVYLDMSKNRIETV--DMDISGCEALEDLLLSSNMLQQL 268
Score = 89.8 bits (213), Expect = 1e-17
Identities = 57/181 (31%), Positives = 85/181 (46%)
Frame = +2
Query: 185 IPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNL 364
+PG + + +L + KN+I ++ P IG LK L L
Sbjct: 222 LPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTL 281
Query: 365 NLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEM 544
+ N L +L IG+L LE F C+ L+ +P IG L L T N L +P E+
Sbjct: 282 KVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREI 341
Query: 545 TSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 724
S + ++L +N++E LP+ + +M L NL +NRL+ P S K KEL L L+ N
Sbjct: 342 GSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDN 401
Query: 725 Q 727
Q
Sbjct: 402 Q 402
Score = 85.0 bits (201), Expect = 3e-16
Identities = 52/200 (26%), Positives = 90/200 (45%)
Frame = +2
Query: 152 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
+LS+ +++ +P + + + ++ L + KN + FP P
Sbjct: 73 KLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPD 132
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
L NL L L+ L L G L KL LK +PK + KL QL+
Sbjct: 133 GFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLG 192
Query: 512 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 691
NE +PE + + LR L ++NN ++ LP ++ ++ LV+ ++ NR+E I C
Sbjct: 193 NNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGC 252
Query: 692 KELMFLQLNSNQISSVPANL 751
+ L L L+SN + +P ++
Sbjct: 253 EALEDLLLSSNMLQQLPDSI 272
Score = 75.8 bits (178), Expect = 2e-13
Identities = 50/199 (25%), Positives = 86/199 (43%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L + +P ++ ++E L L N+ P P
Sbjct: 166 LELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGS 225
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
IG LK LV L++S N + + +I E LE + L+++P IG L +L T
Sbjct: 226 IGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDD 285
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N+L +P + +L+ L N++E+LP T+ + +L + N L + P I CK
Sbjct: 286 NQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCK 345
Query: 695 ELMFLQLNSNQISSVPANL 751
+ + L SN++ +P +
Sbjct: 346 NVTVMSLRSNKLEFLPEEI 364
Score = 51.2 bits (117), Expect = 4e-06
Identities = 38/157 (24%), Positives = 69/157 (43%), Gaps = 1/157 (0%)
Frame = +2
Query: 362 LNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE 538
L+ S+ L + E+ + E+ LE + + ++E+PK++ L N+L +P
Sbjct: 27 LDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPT 86
Query: 539 EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLN 718
+ SL L+ L + N ++ P+ + L N + + P + L L LN
Sbjct: 87 TIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLN 146
Query: 719 SNQISSVPANLDTSLVPGLXMIDLRSNPICELSHPEH 829
+ +PAN LV L +++LR N + L H
Sbjct: 147 DAFLEFLPANFG-RLVK-LRILELRENHLKTLPKSMH 181
Score = 48.0 bits (109), Expect = 4e-05
Identities = 39/164 (23%), Positives = 67/164 (40%), Gaps = 1/164 (0%)
Frame = +2
Query: 326 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
P E+ N + L L L N + L ++ + + L L +P I L L
Sbjct: 38 PKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKEL 97
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 682
N ++ PE + L + N I LPD ++ L L + LE P++
Sbjct: 98 DISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANF 157
Query: 683 LKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
+ +L L+L N + ++P ++ + L +DL +N EL
Sbjct: 158 GRLVKLRILELRENHLKTLPKSMHK--LAQLERLDLGNNEFGEL 199
Score = 47.6 bits (108), Expect = 6e-05
Identities = 36/149 (24%), Positives = 63/149 (42%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ + ++P + ++ L + N++++ P P+
Sbjct: 258 LLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPST 317
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
IG L +L L + N L L EIG + + L+ +P+EIG++ +L
Sbjct: 318 IGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSD 377
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETL 601
N LK +P T L +L L L +NQ + L
Sbjct: 378 NRLKNLPFSFTKLKELAALWLSDNQSKAL 406
>AL117353-1|CAI23423.1| 1495|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1495
Score = 94.7 bits (225), Expect = 4e-19
Identities = 65/220 (29%), Positives = 101/220 (45%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ +I E+P L+ C + L + N +S P P
Sbjct: 56 LYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPEN 115
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
I K L + S NP++ L L L + N L+ +P G+L +L R
Sbjct: 116 IKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRE 175
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N LKT+P+ M LA+L L L NN+ LP+ +D++ L + NN L+ P SI K K
Sbjct: 176 NHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLK 235
Query: 695 ELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
L++L ++ N+I +V ++D S L + L SN + +L
Sbjct: 236 MLVYLDMSKNRIETV--DMDISGCEALEDLLLSSNMLQQL 273
Score = 89.8 bits (213), Expect = 1e-17
Identities = 57/181 (31%), Positives = 85/181 (46%)
Frame = +2
Query: 185 IPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNL 364
+PG + + +L + KN+I ++ P IG LK L L
Sbjct: 227 LPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTL 286
Query: 365 NLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEM 544
+ N L +L IG+L LE F C+ L+ +P IG L L T N L +P E+
Sbjct: 287 KVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREI 346
Query: 545 TSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 724
S + ++L +N++E LP+ + +M L NL +NRL+ P S K KEL L L+ N
Sbjct: 347 GSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDN 406
Query: 725 Q 727
Q
Sbjct: 407 Q 407
Score = 85.0 bits (201), Expect = 3e-16
Identities = 52/200 (26%), Positives = 90/200 (45%)
Frame = +2
Query: 152 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
+LS+ +++ +P + + + ++ L + KN + FP P
Sbjct: 78 KLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPD 137
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
L NL L L+ L L G L KL LK +PK + KL QL+
Sbjct: 138 GFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLG 197
Query: 512 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 691
NE +PE + + LR L ++NN ++ LP ++ ++ LV+ ++ NR+E I C
Sbjct: 198 NNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGC 257
Query: 692 KELMFLQLNSNQISSVPANL 751
+ L L L+SN + +P ++
Sbjct: 258 EALEDLLLSSNMLQQLPDSI 277
Score = 75.8 bits (178), Expect = 2e-13
Identities = 50/199 (25%), Positives = 86/199 (43%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L + +P ++ ++E L L N+ P P
Sbjct: 171 LELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGS 230
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
IG LK LV L++S N + + +I E LE + L+++P IG L +L T
Sbjct: 231 IGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDD 290
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N+L +P + +L+ L N++E+LP T+ + +L + N L + P I CK
Sbjct: 291 NQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCK 350
Query: 695 ELMFLQLNSNQISSVPANL 751
+ + L SN++ +P +
Sbjct: 351 NVTVMSLRSNKLEFLPEEI 369
Score = 51.2 bits (117), Expect = 4e-06
Identities = 38/157 (24%), Positives = 69/157 (43%), Gaps = 1/157 (0%)
Frame = +2
Query: 362 LNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE 538
L+ S+ L + E+ + E+ LE + + ++E+PK++ L N+L +P
Sbjct: 32 LDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPT 91
Query: 539 EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLN 718
+ SL L+ L + N ++ P+ + L N + + P + L L LN
Sbjct: 92 TIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLN 151
Query: 719 SNQISSVPANLDTSLVPGLXMIDLRSNPICELSHPEH 829
+ +PAN LV L +++LR N + L H
Sbjct: 152 DAFLEFLPANFG-RLVK-LRILELRENHLKTLPKSMH 186
Score = 48.0 bits (109), Expect = 4e-05
Identities = 39/164 (23%), Positives = 67/164 (40%), Gaps = 1/164 (0%)
Frame = +2
Query: 326 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
P E+ N + L L L N + L ++ + + L L +P I L L
Sbjct: 43 PKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKEL 102
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 682
N ++ PE + L + N I LPD ++ L L + LE P++
Sbjct: 103 DISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANF 162
Query: 683 LKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
+ +L L+L N + ++P ++ + L +DL +N EL
Sbjct: 163 GRLVKLRILELRENHLKTLPKSMHK--LAQLERLDLGNNEFGEL 204
Score = 47.6 bits (108), Expect = 6e-05
Identities = 36/149 (24%), Positives = 63/149 (42%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ + ++P + ++ L + N++++ P P+
Sbjct: 263 LLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPST 322
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
IG L +L L + N L L EIG + + L+ +P+EIG++ +L
Sbjct: 323 IGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSD 382
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETL 601
N LK +P T L +L L L +NQ + L
Sbjct: 383 NRLKNLPFSFTKLKELAALWLSDNQSKAL 411
>AF434715-1|AAL28133.1| 1537|Homo sapiens densin-180 protein.
Length = 1537
Score = 94.7 bits (225), Expect = 4e-19
Identities = 65/220 (29%), Positives = 101/220 (45%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ +I E+P L+ C + L + N +S P P
Sbjct: 51 LYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPEN 110
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
I K L + S NP++ L L L + N L+ +P G+L +L R
Sbjct: 111 IKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRE 170
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N LKT+P+ M LA+L L L NN+ LP+ +D++ L + NN L+ P SI K K
Sbjct: 171 NHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLK 230
Query: 695 ELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
L++L ++ N+I +V ++D S L + L SN + +L
Sbjct: 231 MLVYLDMSKNRIETV--DMDISGCEALEDLLLSSNMLQQL 268
Score = 89.8 bits (213), Expect = 1e-17
Identities = 57/181 (31%), Positives = 85/181 (46%)
Frame = +2
Query: 185 IPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNL 364
+PG + + +L + KN+I ++ P IG LK L L
Sbjct: 222 LPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTL 281
Query: 365 NLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEM 544
+ N L +L IG+L LE F C+ L+ +P IG L L T N L +P E+
Sbjct: 282 KVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREI 341
Query: 545 TSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSN 724
S + ++L +N++E LP+ + +M L NL +NRL+ P S K KEL L L+ N
Sbjct: 342 GSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDN 401
Query: 725 Q 727
Q
Sbjct: 402 Q 402
Score = 85.0 bits (201), Expect = 3e-16
Identities = 52/200 (26%), Positives = 90/200 (45%)
Frame = +2
Query: 152 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
+LS+ +++ +P + + + ++ L + KN + FP P
Sbjct: 73 KLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPD 132
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
L NL L L+ L L G L KL LK +PK + KL QL+
Sbjct: 133 GFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLG 192
Query: 512 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 691
NE +PE + + LR L ++NN ++ LP ++ ++ LV+ ++ NR+E I C
Sbjct: 193 NNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGC 252
Query: 692 KELMFLQLNSNQISSVPANL 751
+ L L L+SN + +P ++
Sbjct: 253 EALEDLLLSSNMLQQLPDSI 272
Score = 75.8 bits (178), Expect = 2e-13
Identities = 50/199 (25%), Positives = 86/199 (43%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L + +P ++ ++E L L N+ P P
Sbjct: 166 LELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGS 225
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
IG LK LV L++S N + + +I E LE + L+++P IG L +L T
Sbjct: 226 IGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDD 285
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N+L +P + +L+ L N++E+LP T+ + +L + N L + P I CK
Sbjct: 286 NQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCK 345
Query: 695 ELMFLQLNSNQISSVPANL 751
+ + L SN++ +P +
Sbjct: 346 NVTVMSLRSNKLEFLPEEI 364
Score = 51.2 bits (117), Expect = 4e-06
Identities = 38/157 (24%), Positives = 69/157 (43%), Gaps = 1/157 (0%)
Frame = +2
Query: 362 LNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE 538
L+ S+ L + E+ + E+ LE + + ++E+PK++ L N+L +P
Sbjct: 27 LDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPT 86
Query: 539 EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLN 718
+ SL L+ L + N ++ P+ + L N + + P + L L LN
Sbjct: 87 TIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLN 146
Query: 719 SNQISSVPANLDTSLVPGLXMIDLRSNPICELSHPEH 829
+ +PAN LV L +++LR N + L H
Sbjct: 147 DAFLEFLPANFG-RLVK-LRILELRENHLKTLPKSMH 181
Score = 48.0 bits (109), Expect = 4e-05
Identities = 39/164 (23%), Positives = 67/164 (40%), Gaps = 1/164 (0%)
Frame = +2
Query: 326 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
P E+ N + L L L N + L ++ + + L L +P I L L
Sbjct: 38 PKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKEL 97
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 682
N ++ PE + L + N I LPD ++ L L + LE P++
Sbjct: 98 DISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANF 157
Query: 683 LKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
+ +L L+L N + ++P ++ + L +DL +N EL
Sbjct: 158 GRLVKLRILELRENHLKTLPKSMHK--LAQLERLDLGNNEFGEL 199
Score = 47.6 bits (108), Expect = 6e-05
Identities = 36/149 (24%), Positives = 63/149 (42%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ + ++P + ++ L + N++++ P P+
Sbjct: 258 LLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPST 317
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
IG L +L L + N L L EIG + + L+ +P+EIG++ +L
Sbjct: 318 IGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSD 377
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETL 601
N LK +P T L +L L L +NQ + L
Sbjct: 378 NRLKNLPFSFTKLKELAALWLSDNQSKAL 406
>BC014904-1|AAH14904.1| 893|Homo sapiens leucine-rich repeats and
death domain containing protein.
Length = 893
Score = 93.9 bits (223), Expect = 6e-19
Identities = 54/163 (33%), Positives = 90/163 (55%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P + L +L +L+LS+N L L + + L A + L E+P+ +G L L
Sbjct: 118 PAGLSGLAHLAHLDLSFNSLETLPACVLQMRGLGALLLSHNCLSELPEALGALPALTFLT 177
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
N L+T+P + +L+ L+ L L N ++TLP + + +L+ NL +NRL+ P+S+
Sbjct: 178 VTHNRLQTLPPALGALSTLQRLDLSQNLLDTLPPEIGGLGSLLELNLASNRLQSLPASLA 237
Query: 686 KCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
+ L L L+SN ++SVPA D + +P L +DLR N + +L
Sbjct: 238 GLRSLRLLVLHSNLLASVPA--DLARLPLLTRLDLRDNQLRDL 278
Score = 60.9 bits (141), Expect = 6e-09
Identities = 45/164 (27%), Positives = 76/164 (46%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P + ++ L L LS+N L+ L +G L L L+ +P +G L+ L
Sbjct: 141 PACVLQMRGLGALLLSHNCLSELPEALGALPALTFLTVTHNRLQTLPPALGALSTLQRLD 200
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
N L T+P E+ L L L L +N++++LP ++ + +L L +N L P+ +
Sbjct: 201 LSQNLLDTLPPEIGGLGSLLELNLASNRLQSLPASLAGLRSLRLLVLHSNLLASVPADLA 260
Query: 686 KCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELS 817
+ L L L NQ+ +P L + + L+ NP+ E S
Sbjct: 261 RLPLLTRLDLRDNQLRDLPPELLDA-----PFVRLQGNPLGEAS 299
Score = 48.4 bits (110), Expect = 3e-05
Identities = 32/126 (25%), Positives = 57/126 (45%)
Frame = +2
Query: 437 CNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMD 616
C R L +P + L L N L+T+P + + L L L +N + LP+ +
Sbjct: 109 CLRGALTNLPAGLSGLAHLAHLDLSFNSLETLPACVLQMRGLGALLLSHNCLSELPEALG 168
Query: 617 RMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRS 796
+ AL + +NRL+ P ++ L L L+ N + ++P + + L ++L S
Sbjct: 169 ALPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLLDTLPPEIGG--LGSLLELNLAS 226
Query: 797 NPICEL 814
N + L
Sbjct: 227 NRLQSL 232
>AF274972-1|AAG13461.1| 910|Homo sapiens PIDD protein.
Length = 910
Score = 93.9 bits (223), Expect = 6e-19
Identities = 54/163 (33%), Positives = 90/163 (55%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P + L +L +L+LS+N L L + + L A + L E+P+ +G L L
Sbjct: 118 PAGLSGLAHLAHLDLSFNSLETLPACVLQMRGLGALLLSHNCLSELPEALGALPALTFLT 177
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
N L+T+P + +L+ L+ L L N ++TLP + + +L+ NL +NRL+ P+S+
Sbjct: 178 VTHNRLQTLPPALGALSTLQRLDLSQNLLDTLPPEIGGLGSLLELNLASNRLQSLPASLA 237
Query: 686 KCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
+ L L L+SN ++SVPA D + +P L +DLR N + +L
Sbjct: 238 GLRSLRLLVLHSNLLASVPA--DLARLPLLTRLDLRDNQLRDL 278
Score = 60.9 bits (141), Expect = 6e-09
Identities = 45/164 (27%), Positives = 76/164 (46%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P + ++ L L LS+N L+ L +G L L L+ +P +G L+ L
Sbjct: 141 PACVLQMRGLGALLLSHNCLSELPEALGALPALTFLTVTHNRLQTLPPALGALSTLQRLD 200
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
N L T+P E+ L L L L +N++++LP ++ + +L L +N L P+ +
Sbjct: 201 LSQNLLDTLPPEIGGLGSLLELNLASNRLQSLPASLAGLRSLRLLVLHSNLLASVPADLA 260
Query: 686 KCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELS 817
+ L L L NQ+ +P L + + L+ NP+ E S
Sbjct: 261 RLPLLTRLDLRDNQLRDLPPELLDA-----PFVRLQGNPLGEAS 299
Score = 48.4 bits (110), Expect = 3e-05
Identities = 32/126 (25%), Positives = 57/126 (45%)
Frame = +2
Query: 437 CNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMD 616
C R L +P + L L N L+T+P + + L L L +N + LP+ +
Sbjct: 109 CLRGALTNLPAGLSGLAHLAHLDLSFNSLETLPACVLQMRGLGALLLSHNCLSELPEALG 168
Query: 617 RMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRS 796
+ AL + +NRL+ P ++ L L L+ N + ++P + + L ++L S
Sbjct: 169 ALPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLLDTLPPEIGG--LGSLLELNLAS 226
Query: 797 NPICEL 814
N + L
Sbjct: 227 NRLQSL 232
>BC003193-1|AAH03193.1| 524|Homo sapiens leucine rich repeat
containing 1 protein.
Length = 524
Score = 88.6 bits (210), Expect = 2e-17
Identities = 57/217 (26%), Positives = 101/217 (46%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L EI +P + L ++ L+L N++S P E P E
Sbjct: 179 LDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEE 238
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
I L +L +L +S N L + IG L+KL ++ L ++P+ +G+ L
Sbjct: 239 ISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLPEAVGECESLTELVLTE 298
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N+L T+P+ + L KL L + N++ +LP + +L +R+NRL + P+ + +
Sbjct: 299 NQLLTLPKSIGKLKKLSNLNADRNKLVSLPKEIGGCCSLTVFCVRDNRLTRIPAEVSQAT 358
Query: 695 ELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
EL L + N++ +P +L + L + D +S P+
Sbjct: 359 ELHVLDVAGNRLLHLPLSLTALKLKALWLSDNQSQPL 395
Score = 88.2 bits (209), Expect = 3e-17
Identities = 63/213 (29%), Positives = 93/213 (43%)
Frame = +2
Query: 176 ITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 355
+T +P L +E L L N+I P P EIGNLKNL
Sbjct: 163 LTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNL 222
Query: 356 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 535
+ L++S N L L EI L L ++ L+ IP IGKL +L N L +P
Sbjct: 223 LCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLP 282
Query: 536 EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQL 715
E + L L L NQ+ TLP ++ ++ L + N N+L P I C L +
Sbjct: 283 EAVGECESLTELVLTENQLLTLPKSIGKLKKLSNLNADRNKLVSLPKEIGGCCSLTVFCV 342
Query: 716 NSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
N+++ +PA + S L ++D+ N + L
Sbjct: 343 RDNRLTRIPA--EVSQATELHVLDVAGNRLLHL 373
Score = 87.8 bits (208), Expect = 4e-17
Identities = 54/196 (27%), Positives = 88/196 (44%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L ++ EI EIP + C ++ N ++ P P
Sbjct: 87 LDVSRNEIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPEN 146
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
IGNL NL +L L N L L + L +LE + +P+ IG L L G
Sbjct: 147 IGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDG 206
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N+L +P+E+ +L L L + N++E LP+ + +T+L + N LE P I K K
Sbjct: 207 NQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKLK 266
Query: 695 ELMFLQLNSNQISSVP 742
+L L+++ N+++ +P
Sbjct: 267 KLSILKVDQNRLTQLP 282
Score = 83.8 bits (198), Expect = 7e-16
Identities = 54/199 (27%), Positives = 88/199 (44%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ ++ E+P + +++ L L N+I P E P
Sbjct: 41 LLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNEIPEIPES 100
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
I K L + S NPL L +L+ L N I L+ +P+ IG L L + R
Sbjct: 101 ISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLASLELRE 160
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N L +P+ +T L +L L L NN+I LP+++ + L L N+L + P I K
Sbjct: 161 NLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLK 220
Query: 695 ELMFLQLNSNQISSVPANL 751
L+ L ++ N++ +P +
Sbjct: 221 NLLCLDVSENRLERLPEEI 239
Score = 68.5 bits (160), Expect = 3e-11
Identities = 42/146 (28%), Positives = 68/146 (46%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P + L L L LS N + L PEI + +L +R + EIP+ I L
Sbjct: 52 PEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNEIPEIPESISFCKALQVAD 111
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
GN L +PE L L L++ + +++LP+ + + L LR N L P S+
Sbjct: 112 FSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPDSLT 171
Query: 686 KCKELMFLQLNSNQISSVPANLDTSL 763
+ + L L L +N+I ++P ++ L
Sbjct: 172 QLRRLEELDLGNNEIYNLPESIGALL 197
Score = 52.0 bits (119), Expect = 3e-06
Identities = 39/156 (25%), Positives = 68/156 (43%)
Frame = +2
Query: 347 KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELK 526
++L L L N L L + L KL + ++ +P EI QL NE+
Sbjct: 36 RSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNEIP 95
Query: 527 TIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMF 706
IPE ++ L+ N + LP++ + L ++ + L+ P +I L
Sbjct: 96 EIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLAS 155
Query: 707 LQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
L+L N ++ +P +L + + L +DL +N I L
Sbjct: 156 LELRENLLTYLPDSL--TQLRRLEELDLGNNEIYNL 189
>AL513211-1|CAI17358.1| 524|Homo sapiens leucine rich repeat
containing 1 protein.
Length = 524
Score = 88.6 bits (210), Expect = 2e-17
Identities = 57/217 (26%), Positives = 101/217 (46%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L EI +P + L ++ L+L N++S P E P E
Sbjct: 179 LDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEE 238
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
I L +L +L +S N L + IG L+KL ++ L ++P+ +G+ L
Sbjct: 239 ISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLPEAVGECESLTELVLTE 298
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N+L T+P+ + L KL L + N++ +LP + +L +R+NRL + P+ + +
Sbjct: 299 NQLLTLPKSIGKLKKLSNLNADRNKLVSLPKEIGGCCSLTVFCVRDNRLTRIPAEVSQAT 358
Query: 695 ELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
EL L + N++ +P +L + L + D +S P+
Sbjct: 359 ELHVLDVAGNRLLHLPLSLTALKLKALWLSDNQSQPL 395
Score = 88.2 bits (209), Expect = 3e-17
Identities = 63/213 (29%), Positives = 93/213 (43%)
Frame = +2
Query: 176 ITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 355
+T +P L +E L L N+I P P EIGNLKNL
Sbjct: 163 LTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNL 222
Query: 356 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 535
+ L++S N L L EI L L ++ L+ IP IGKL +L N L +P
Sbjct: 223 LCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLP 282
Query: 536 EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQL 715
E + L L L NQ+ TLP ++ ++ L + N N+L P I C L +
Sbjct: 283 EAVGECESLTELVLTENQLLTLPKSIGKLKKLSNLNADRNKLVSLPKEIGGCCSLTVFCV 342
Query: 716 NSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
N+++ +PA + S L ++D+ N + L
Sbjct: 343 RDNRLTRIPA--EVSQATELHVLDVAGNRLLHL 373
Score = 87.8 bits (208), Expect = 4e-17
Identities = 54/196 (27%), Positives = 88/196 (44%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L ++ EI EIP + C ++ N ++ P P
Sbjct: 87 LDVSRNEIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPEN 146
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
IGNL NL +L L N L L + L +LE + +P+ IG L L G
Sbjct: 147 IGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDG 206
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N+L +P+E+ +L L L + N++E LP+ + +T+L + N LE P I K K
Sbjct: 207 NQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKLK 266
Query: 695 ELMFLQLNSNQISSVP 742
+L L+++ N+++ +P
Sbjct: 267 KLSILKVDQNRLTQLP 282
Score = 83.8 bits (198), Expect = 7e-16
Identities = 54/199 (27%), Positives = 88/199 (44%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ ++ E+P + +++ L L N+I P E P
Sbjct: 41 LLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNEIPEIPES 100
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
I K L + S NPL L +L+ L N I L+ +P+ IG L L + R
Sbjct: 101 ISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLASLELRE 160
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N L +P+ +T L +L L L NN+I LP+++ + L L N+L + P I K
Sbjct: 161 NLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLK 220
Query: 695 ELMFLQLNSNQISSVPANL 751
L+ L ++ N++ +P +
Sbjct: 221 NLLCLDVSENRLERLPEEI 239
Score = 68.5 bits (160), Expect = 3e-11
Identities = 42/146 (28%), Positives = 68/146 (46%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P + L L L LS N + L PEI + +L +R + EIP+ I L
Sbjct: 52 PEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNEIPEIPESISFCKALQVAD 111
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
GN L +PE L L L++ + +++LP+ + + L LR N L P S+
Sbjct: 112 FSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPDSLT 171
Query: 686 KCKELMFLQLNSNQISSVPANLDTSL 763
+ + L L L +N+I ++P ++ L
Sbjct: 172 QLRRLEELDLGNNEIYNLPESIGALL 197
Score = 52.0 bits (119), Expect = 3e-06
Identities = 39/156 (25%), Positives = 68/156 (43%)
Frame = +2
Query: 347 KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELK 526
++L L L N L L + L KL + ++ +P EI QL NE+
Sbjct: 36 RSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNEIP 95
Query: 527 TIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMF 706
IPE ++ L+ N + LP++ + L ++ + L+ P +I L
Sbjct: 96 EIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLAS 155
Query: 707 LQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
L+L N ++ +P +L + + L +DL +N I L
Sbjct: 156 LELRENLLTYLPDSL--TQLRRLEELDLGNNEIYNL 189
>AL033384-1|CAI21666.1| 524|Homo sapiens leucine rich repeat
containing 1 protein.
Length = 524
Score = 88.6 bits (210), Expect = 2e-17
Identities = 57/217 (26%), Positives = 101/217 (46%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L EI +P + L ++ L+L N++S P E P E
Sbjct: 179 LDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEE 238
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
I L +L +L +S N L + IG L+KL ++ L ++P+ +G+ L
Sbjct: 239 ISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLPEAVGECESLTELVLTE 298
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N+L T+P+ + L KL L + N++ +LP + +L +R+NRL + P+ + +
Sbjct: 299 NQLLTLPKSIGKLKKLSNLNADRNKLVSLPKEIGGCCSLTVFCVRDNRLTRIPAEVSQAT 358
Query: 695 ELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
EL L + N++ +P +L + L + D +S P+
Sbjct: 359 ELHVLDVAGNRLLHLPLSLTALKLKALWLSDNQSQPL 395
Score = 88.2 bits (209), Expect = 3e-17
Identities = 63/213 (29%), Positives = 93/213 (43%)
Frame = +2
Query: 176 ITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 355
+T +P L +E L L N+I P P EIGNLKNL
Sbjct: 163 LTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNL 222
Query: 356 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 535
+ L++S N L L EI L L ++ L+ IP IGKL +L N L +P
Sbjct: 223 LCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLP 282
Query: 536 EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQL 715
E + L L L NQ+ TLP ++ ++ L + N N+L P I C L +
Sbjct: 283 EAVGECESLTELVLTENQLLTLPKSIGKLKKLSNLNADRNKLVSLPKEIGGCCSLTVFCV 342
Query: 716 NSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
N+++ +PA + S L ++D+ N + L
Sbjct: 343 RDNRLTRIPA--EVSQATELHVLDVAGNRLLHL 373
Score = 87.8 bits (208), Expect = 4e-17
Identities = 54/196 (27%), Positives = 88/196 (44%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L ++ EI EIP + C ++ N ++ P P
Sbjct: 87 LDVSRNEIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPEN 146
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
IGNL NL +L L N L L + L +LE + +P+ IG L L G
Sbjct: 147 IGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDG 206
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N+L +P+E+ +L L L + N++E LP+ + +T+L + N LE P I K K
Sbjct: 207 NQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKLK 266
Query: 695 ELMFLQLNSNQISSVP 742
+L L+++ N+++ +P
Sbjct: 267 KLSILKVDQNRLTQLP 282
Score = 83.8 bits (198), Expect = 7e-16
Identities = 54/199 (27%), Positives = 88/199 (44%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ ++ E+P + +++ L L N+I P E P
Sbjct: 41 LLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNEIPEIPES 100
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
I K L + S NPL L +L+ L N I L+ +P+ IG L L + R
Sbjct: 101 ISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLASLELRE 160
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N L +P+ +T L +L L L NN+I LP+++ + L L N+L + P I K
Sbjct: 161 NLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLK 220
Query: 695 ELMFLQLNSNQISSVPANL 751
L+ L ++ N++ +P +
Sbjct: 221 NLLCLDVSENRLERLPEEI 239
Score = 68.5 bits (160), Expect = 3e-11
Identities = 42/146 (28%), Positives = 68/146 (46%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P + L L L LS N + L PEI + +L +R + EIP+ I L
Sbjct: 52 PEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNEIPEIPESISFCKALQVAD 111
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
GN L +PE L L L++ + +++LP+ + + L LR N L P S+
Sbjct: 112 FSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPDSLT 171
Query: 686 KCKELMFLQLNSNQISSVPANLDTSL 763
+ + L L L +N+I ++P ++ L
Sbjct: 172 QLRRLEELDLGNNEIYNLPESIGALL 197
Score = 52.0 bits (119), Expect = 3e-06
Identities = 39/156 (25%), Positives = 68/156 (43%)
Frame = +2
Query: 347 KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELK 526
++L L L N L L + L KL + ++ +P EI QL NE+
Sbjct: 36 RSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNEIP 95
Query: 527 TIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMF 706
IPE ++ L+ N + LP++ + L ++ + L+ P +I L
Sbjct: 96 EIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLAS 155
Query: 707 LQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
L+L N ++ +P +L + + L +DL +N I L
Sbjct: 156 LELRENLLTYLPDSL--TQLRRLEELDLGNNEIYNL 189
>AF359380-1|AAK72246.1| 524|Homo sapiens LANO adaptor protein
protein.
Length = 524
Score = 88.6 bits (210), Expect = 2e-17
Identities = 57/217 (26%), Positives = 101/217 (46%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L EI +P + L ++ L+L N++S P E P E
Sbjct: 179 LDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEE 238
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
I L +L +L +S N L + IG L+KL ++ L ++P+ +G+ L
Sbjct: 239 ISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLPEAVGECESLTELVLTE 298
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N+L T+P+ + L KL L + N++ +LP + +L +R+NRL + P+ + +
Sbjct: 299 NQLLTLPKSIGKLKKLSNLNADRNKLVSLPKEIGGCCSLTVFCVRDNRLTRIPAEVSQAT 358
Query: 695 ELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
EL L + N++ +P +L + L + D +S P+
Sbjct: 359 ELHVLDVAGNRLLHLPLSLTALKLKALWLSDNQSQPL 395
Score = 88.2 bits (209), Expect = 3e-17
Identities = 63/213 (29%), Positives = 93/213 (43%)
Frame = +2
Query: 176 ITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 355
+T +P L +E L L N+I P P EIGNLKNL
Sbjct: 163 LTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNL 222
Query: 356 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 535
+ L++S N L L EI L L ++ L+ IP IGKL +L N L +P
Sbjct: 223 LCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLP 282
Query: 536 EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQL 715
E + L L L NQ+ TLP ++ ++ L + N N+L P I C L +
Sbjct: 283 EAVGECESLTELVLTENQLLTLPKSIGKLKKLSNLNADRNKLVSLPKEIGGCCSLTVFCV 342
Query: 716 NSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
N+++ +PA + S L ++D+ N + L
Sbjct: 343 RDNRLTRIPA--EVSQATELHVLDVAGNRLLHL 373
Score = 87.8 bits (208), Expect = 4e-17
Identities = 54/196 (27%), Positives = 88/196 (44%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L ++ EI EIP + C ++ N ++ P P
Sbjct: 87 LDVSRNEIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPEN 146
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
IGNL NL +L L N L L + L +LE + +P+ IG L L G
Sbjct: 147 IGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDG 206
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N+L +P+E+ +L L L + N++E LP+ + +T+L + N LE P I K K
Sbjct: 207 NQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKLK 266
Query: 695 ELMFLQLNSNQISSVP 742
+L L+++ N+++ +P
Sbjct: 267 KLSILKVDQNRLTQLP 282
Score = 83.8 bits (198), Expect = 7e-16
Identities = 54/199 (27%), Positives = 88/199 (44%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ ++ E+P + +++ L L N+I P E P
Sbjct: 41 LLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNEIPEIPES 100
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
I K L + S NPL L +L+ L N I L+ +P+ IG L L + R
Sbjct: 101 ISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLASLELRE 160
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N L +P+ +T L +L L L NN+I LP+++ + L L N+L + P I K
Sbjct: 161 NLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLK 220
Query: 695 ELMFLQLNSNQISSVPANL 751
L+ L ++ N++ +P +
Sbjct: 221 NLLCLDVSENRLERLPEEI 239
Score = 68.5 bits (160), Expect = 3e-11
Identities = 42/146 (28%), Positives = 68/146 (46%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P + L L L LS N + L PEI + +L +R + EIP+ I L
Sbjct: 52 PEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNEIPEIPESISFCKALQVAD 111
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
GN L +PE L L L++ + +++LP+ + + L LR N L P S+
Sbjct: 112 FSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPDSLT 171
Query: 686 KCKELMFLQLNSNQISSVPANLDTSL 763
+ + L L L +N+I ++P ++ L
Sbjct: 172 QLRRLEELDLGNNEIYNLPESIGALL 197
Score = 52.0 bits (119), Expect = 3e-06
Identities = 39/156 (25%), Positives = 68/156 (43%)
Frame = +2
Query: 347 KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELK 526
++L L L N L L + L KL + ++ +P EI QL NE+
Sbjct: 36 RSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNEIP 95
Query: 527 TIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMF 706
IPE ++ L+ N + LP++ + L ++ + L+ P +I L
Sbjct: 96 EIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLAS 155
Query: 707 LQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
L+L N ++ +P +L + + L +DL +N I L
Sbjct: 156 LELRENLLTYLPDSL--TQLRRLEELDLGNNEIYNL 189
>AF332199-1|AAK69623.1| 524|Homo sapiens leucine-rich repeats
protein protein.
Length = 524
Score = 88.6 bits (210), Expect = 2e-17
Identities = 57/217 (26%), Positives = 101/217 (46%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L EI +P + L ++ L+L N++S P E P E
Sbjct: 179 LDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEE 238
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
I L +L +L +S N L + IG L+KL ++ L ++P+ +G+ L
Sbjct: 239 ISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLPEAVGECESLTELVLTE 298
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N+L T+P+ + L KL L + N++ +LP + +L +R+NRL + P+ + +
Sbjct: 299 NQLLTLPKSIGKLKKLSNLNADRNKLVSLPKEIGGCCSLTVFCVRDNRLTRIPAEVSQAT 358
Query: 695 ELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
EL L + N++ +P +L + L + D +S P+
Sbjct: 359 ELHVLDVAGNRLLHLPLSLTALKLKALWLSDNQSQPL 395
Score = 88.2 bits (209), Expect = 3e-17
Identities = 63/213 (29%), Positives = 93/213 (43%)
Frame = +2
Query: 176 ITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 355
+T +P L +E L L N+I P P EIGNLKNL
Sbjct: 163 LTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNL 222
Query: 356 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 535
+ L++S N L L EI L L ++ L+ IP IGKL +L N L +P
Sbjct: 223 LCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLP 282
Query: 536 EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQL 715
E + L L L NQ+ TLP ++ ++ L + N N+L P I C L +
Sbjct: 283 EAVGECESLTELVLTENQLLTLPKSIGKLKKLSNLNADRNKLVSLPKEIGGCCSLTVFCV 342
Query: 716 NSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
N+++ +PA + S L ++D+ N + L
Sbjct: 343 RDNRLTRIPA--EVSQATELHVLDVAGNRLLHL 373
Score = 87.8 bits (208), Expect = 4e-17
Identities = 54/196 (27%), Positives = 88/196 (44%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L ++ EI EIP + C ++ N ++ P P
Sbjct: 87 LDVSRNEIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPEN 146
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
IGNL NL +L L N L L + L +LE + +P+ IG L L G
Sbjct: 147 IGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDG 206
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N+L +P+E+ +L L L + N++E LP+ + +T+L + N LE P I K K
Sbjct: 207 NQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKLK 266
Query: 695 ELMFLQLNSNQISSVP 742
+L L+++ N+++ +P
Sbjct: 267 KLSILKVDQNRLTQLP 282
Score = 83.8 bits (198), Expect = 7e-16
Identities = 54/199 (27%), Positives = 88/199 (44%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ ++ E+P + +++ L L N+I P E P
Sbjct: 41 LLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNEIPEIPES 100
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
I K L + S NPL L +L+ L N I L+ +P+ IG L L + R
Sbjct: 101 ISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLASLELRE 160
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N L +P+ +T L +L L L NN+I LP+++ + L L N+L + P I K
Sbjct: 161 NLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLK 220
Query: 695 ELMFLQLNSNQISSVPANL 751
L+ L ++ N++ +P +
Sbjct: 221 NLLCLDVSENRLERLPEEI 239
Score = 68.5 bits (160), Expect = 3e-11
Identities = 42/146 (28%), Positives = 68/146 (46%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P + L L L LS N + L PEI + +L +R + EIP+ I L
Sbjct: 52 PEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNEIPEIPESISFCKALQVAD 111
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
GN L +PE L L L++ + +++LP+ + + L LR N L P S+
Sbjct: 112 FSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPDSLT 171
Query: 686 KCKELMFLQLNSNQISSVPANLDTSL 763
+ + L L L +N+I ++P ++ L
Sbjct: 172 QLRRLEELDLGNNEIYNLPESIGALL 197
Score = 52.0 bits (119), Expect = 3e-06
Identities = 39/156 (25%), Positives = 68/156 (43%)
Frame = +2
Query: 347 KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELK 526
++L L L N L L + L KL + ++ +P EI QL NE+
Sbjct: 36 RSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNEIP 95
Query: 527 TIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMF 706
IPE ++ L+ N + LP++ + L ++ + L+ P +I L
Sbjct: 96 EIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLAS 155
Query: 707 LQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
L+L N ++ +P +L + + L +DL +N I L
Sbjct: 156 LELRENLLTYLPDSL--TQLRRLEELDLGNNEIYNL 189
>BC058935-1|AAH58935.1| 239|Homo sapiens LRRC57 protein protein.
Length = 239
Score = 86.2 bits (204), Expect = 1e-16
Identities = 49/144 (34%), Positives = 78/144 (54%), Gaps = 2/144 (1%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P IG L +L+L+ N L VL EI +L+KLE N L+E+P G+L+ L T
Sbjct: 55 PLLIGKFTLLKSLSLNNNKLTVLPDEICNLKKLETLSLNNNHLRELPSTFGQLSALKTLS 114
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
GN+L +P ++ SL L + L NQI ++PD++ + ++ NL N++ Q I
Sbjct: 115 LSGNQLGALPPQLCSLRHLDVMDLSKNQIRSIPDSVGEL-QVIELNLNQNQISQISVKIS 173
Query: 686 KCKELMFLQLNSN--QISSVPANL 751
C L L+L N ++S +P ++
Sbjct: 174 CCPRLKILRLEENCLELSMLPQSI 197
Score = 49.6 bits (113), Expect = 1e-05
Identities = 28/84 (33%), Positives = 44/84 (52%), Gaps = 2/84 (2%)
Frame = +2
Query: 500 FGARGNELKTIPEEMTSL-AKLRWLTLENNQIETLPDTM-DRMTALVHCNLRNNRLEQFP 673
F + L P ++ L + LR + L NN+IE+LP + + T L +L NN+L P
Sbjct: 19 FQLKDRGLTEFPADLQKLTSNLRTIDLSNNKIESLPPLLIGKFTLLKSLSLNNNKLTVLP 78
Query: 674 SSILKCKELMFLQLNSNQISSVPA 745
I K+L L LN+N + +P+
Sbjct: 79 DEICNLKKLETLSLNNNHLRELPS 102
>AK094891-1|BAC04451.1| 239|Homo sapiens protein ( Homo sapiens
cDNA FLJ37572 fis, clone BRCOC2002751, weakly similar to
RAS SUPPRESSOR PROTEIN 1. ).
Length = 239
Score = 86.2 bits (204), Expect = 1e-16
Identities = 49/144 (34%), Positives = 78/144 (54%), Gaps = 2/144 (1%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P IG L +L+L+ N L VL EI +L+KLE N L+E+P G+L+ L T
Sbjct: 55 PLLIGKFTLLKSLSLNNNKLTVLPDEICNLKKLETLSLNNNHLRELPSTFGQLSALKTLS 114
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
GN+L +P ++ SL L + L NQI ++PD++ + ++ NL N++ Q I
Sbjct: 115 LSGNQLGALPPQLCSLRHLDVMDLSKNQIRSIPDSVGEL-QVIELNLNQNQISQISVKIS 173
Query: 686 KCKELMFLQLNSN--QISSVPANL 751
C L L+L N ++S +P ++
Sbjct: 174 CCPRLKILRLEENCLELSMLPQSI 197
Score = 49.6 bits (113), Expect = 1e-05
Identities = 28/84 (33%), Positives = 44/84 (52%), Gaps = 2/84 (2%)
Frame = +2
Query: 500 FGARGNELKTIPEEMTSL-AKLRWLTLENNQIETLPDTM-DRMTALVHCNLRNNRLEQFP 673
F + L P ++ L + LR + L NN+IE+LP + + T L +L NN+L P
Sbjct: 19 FQLKDRGLTEFPADLQKLTSNLRTIDLSNNKIESLPPLLIGKFTLLKSLSLNNNKLTVLP 78
Query: 674 SSILKCKELMFLQLNSNQISSVPA 745
I K+L L LN+N + +P+
Sbjct: 79 DEICNLKKLETLSLNNNHLRELPS 102
>AK094131-1|BAC04294.1| 239|Homo sapiens (EC 2.4.1.101). protein.
Length = 239
Score = 86.2 bits (204), Expect = 1e-16
Identities = 49/144 (34%), Positives = 78/144 (54%), Gaps = 2/144 (1%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P IG L +L+L+ N L VL EI +L+KLE N L+E+P G+L+ L T
Sbjct: 55 PLLIGKFTLLKSLSLNNNKLTVLPDEICNLKKLETLSLNNNHLRELPSTFGQLSALKTLS 114
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
GN+L +P ++ SL L + L NQI ++PD++ + ++ NL N++ Q I
Sbjct: 115 LSGNQLGALPPQLCSLRHLDVMDLSKNQIRSIPDSVGEL-QVIELNLNQNQISQISVKIS 173
Query: 686 KCKELMFLQLNSN--QISSVPANL 751
C L L+L N ++S +P ++
Sbjct: 174 CCPRLKILRLEENCLELSMLPQSI 197
Score = 49.6 bits (113), Expect = 1e-05
Identities = 28/84 (33%), Positives = 44/84 (52%), Gaps = 2/84 (2%)
Frame = +2
Query: 500 FGARGNELKTIPEEMTSL-AKLRWLTLENNQIETLPDTM-DRMTALVHCNLRNNRLEQFP 673
F + L P ++ L + LR + L NN+IE+LP + + T L +L NN+L P
Sbjct: 19 FQLKDRGLTEFPADLQKLTSNLRTIDLSNNKIESLPPLLIGKFTLLKSLSLNNNKLTVLP 78
Query: 674 SSILKCKELMFLQLNSNQISSVPA 745
I K+L L LN+N + +P+
Sbjct: 79 DEICNLKKLETLSLNNNHLRELPS 102
>D63481-1|BAA09768.3| 1630|Homo sapiens KIAA0147 protein protein.
Length = 1630
Score = 84.2 bits (199), Expect = 5e-16
Identities = 59/218 (27%), Positives = 95/218 (43%)
Frame = +2
Query: 152 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
+L L G ++ +P L + L+L +N++S P E P
Sbjct: 178 QLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSALPPELGNLRRLVCLDVSENRLEELPA 237
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
E+G L L +L LS N L L IG L++L ++ L E+ + IG L
Sbjct: 238 ELGGLVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEVTEAIGDCENLSELILT 297
Query: 512 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 691
N L +P + L KL L ++ N +E LP + AL +LR+NRL P +
Sbjct: 298 ENLLMALPRSLGKLTKLTNLNVDRNHLEALPPEIGGCVALSVLSLRDNRLAVLPPELAHT 357
Query: 692 KELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
EL L + N++ S+P L + L + + ++ P+
Sbjct: 358 TELHVLDVAGNRLQSLPFALTHLNLKALWLAENQAQPM 395
Score = 82.2 bits (194), Expect = 2e-15
Identities = 58/213 (27%), Positives = 93/213 (43%)
Frame = +2
Query: 176 ITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 355
+ +P L +++E L L N + + P P E+GNL+ L
Sbjct: 163 LKSLPASLSFLVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSALPPELGNLRRL 222
Query: 356 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 535
V L++S N L L E+G L L ++ L+ +P IG+L QL N L +
Sbjct: 223 VCLDVSENRLEELPAELGGLVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEVT 282
Query: 536 EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQL 715
E + L L L N + LP ++ ++T L + N+ N LE P I C L L L
Sbjct: 283 EAIGDCENLSELILTENLLMALPRSLGKLTKLTNLNVDRNHLEALPPEIGGCVALSVLSL 342
Query: 716 NSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
N+++ +P L + L ++D+ N + L
Sbjct: 343 RDNRLAVLPPEL--AHTTELHVLDVAGNRLQSL 373
Score = 77.8 bits (183), Expect = 5e-14
Identities = 53/222 (23%), Positives = 99/222 (44%)
Frame = +2
Query: 152 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
+L L+ EI +P + +++ L + +N I P P
Sbjct: 63 KLGLSDNEIQRLPPEVANFMQLVELDVSRNDIPEIPESIKFCKALEIADFSGNPLSRLPD 122
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
L++L +L L+ L L ++G+L L LK +P + L +L+
Sbjct: 123 GFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSLPASLSFLVKLEQLDLG 182
Query: 512 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 691
GN+L+ +P+ + +L LR L L+ NQ+ LP + + LV ++ NRLE+ P+ +
Sbjct: 183 GNDLEVLPDTLGALPNLRELWLDRNQLSALPPELGNLRRLVCLDVSENRLEELPAELGGL 242
Query: 692 KELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELS 817
L L L+ N + +P + + L ++ + N +CE++
Sbjct: 243 VLLTDLLLSQNLLRRLPDGI--GQLKQLSILKVDQNRLCEVT 282
Score = 67.7 bits (158), Expect = 5e-11
Identities = 48/163 (29%), Positives = 72/163 (44%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P L NL L LS N + L PE+ + +L +R + EIP+ I L+
Sbjct: 52 PKPFFRLLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDIPEIPESIKFCKALEIAD 111
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
GN L +P+ T L L L L + ++ LP + + LV LR N L+ P+S+
Sbjct: 112 FSGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSLPASLS 171
Query: 686 KCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
+L L L N + +P L +P L + L N + L
Sbjct: 172 FLVKLEQLDLGGNDLEVLPDTL--GALPNLRELWLDRNQLSAL 212
Score = 56.8 bits (131), Expect = 9e-08
Identities = 39/153 (25%), Positives = 64/153 (41%)
Frame = +2
Query: 347 KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELK 526
++L L L N L L L L + ++ +P E+ QL N++
Sbjct: 36 RSLEELLLDANQLRELPKPFFRLLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDIP 95
Query: 527 TIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMF 706
IPE + L N + LPD ++ +L H L + L+ P + L+
Sbjct: 96 EIPESIKFCKALEIADFSGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGDVGNLANLVT 155
Query: 707 LQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
L+L N + S+PA+L S + L +DL N +
Sbjct: 156 LELRENLLKSLPASL--SFLVKLEQLDLGGNDL 186
>BC008586-1|AAH08586.1| 602|Homo sapiens leucine rich repeat
containing 40 protein.
Length = 602
Score = 84.2 bits (199), Expect = 5e-16
Identities = 59/219 (26%), Positives = 106/219 (48%), Gaps = 1/219 (0%)
Frame = +2
Query: 152 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
+L+++ ++ +P + ++ LYL N+++ P
Sbjct: 132 KLNVSHNKLKILPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPA 191
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
+L +LV LNLS N L L EI +++L+ CN L+ IP E+ + L+ R
Sbjct: 192 SFSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLR 251
Query: 512 GNELKTIPEEMTSLAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQFPSSILK 688
N+L+ +PE S + L+ L + NQIE L + + + +++ +LR+N+L+ P I+
Sbjct: 252 RNKLRFLPE-FPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEIIL 310
Query: 689 CKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
+ L L L++N ISS+P +L L + L NP+
Sbjct: 311 LRSLERLDLSNNDISSLPYSLGNL---HLKFLALEGNPL 346
Score = 81.8 bits (193), Expect = 3e-15
Identities = 50/168 (29%), Positives = 83/168 (49%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P+ I L+NL LN+S+N L +L EI +L L+ + L I + +L+ L+
Sbjct: 121 PSAIRELENLQKLNVSHNKLKILPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLD 180
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
N L T+P +SL+ L L L +N++++LP ++RM L H + +N LE P +
Sbjct: 181 LSNNHLTTVPASFSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELA 240
Query: 686 KCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELSHPEH 829
+ L L L N++ +P SL+ L + + E H +H
Sbjct: 241 GMESLELLYLRRNKLRFLPEFPSCSLLKELH-VGENQIEMLEAEHLKH 287
Score = 77.4 bits (182), Expect = 6e-14
Identities = 50/154 (32%), Positives = 77/154 (50%)
Frame = +2
Query: 344 LKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNEL 523
L L L++ N L L I +LE L+ + LK +P+EI L L + NEL
Sbjct: 104 LPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKILPEEITNLRNLKCLYLQHNEL 163
Query: 524 KTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELM 703
I E L+ L L L NN + T+P + +++LV NL +N L+ P+ I + K L
Sbjct: 164 TCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRLNLSSNELKSLPAEINRMKRLK 223
Query: 704 FLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
L NSN + ++P L + + L ++ LR N +
Sbjct: 224 HLDCNSNLLETIPPEL--AGMESLELLYLRRNKL 255
Score = 73.3 bits (172), Expect = 1e-12
Identities = 47/159 (29%), Positives = 81/159 (50%)
Frame = +2
Query: 350 NLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKT 529
+L L +S N L L ++ L L + L +P I +L L N+LK
Sbjct: 83 DLTKLIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKI 142
Query: 530 IPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFL 709
+PEE+T+L L+ L L++N++ + + ++++ L +L NN L P+S L+ L
Sbjct: 143 LPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRL 202
Query: 710 QLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELSHPE 826
L+SN++ S+PA ++ + L +D SN + E PE
Sbjct: 203 NLSSNELKSLPAEINR--MKRLKHLDCNSN-LLETIPPE 238
Score = 64.5 bits (150), Expect = 4e-10
Identities = 41/135 (30%), Positives = 67/135 (49%), Gaps = 2/135 (1%)
Frame = +2
Query: 326 PTEIGNLKNLVN-LNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
P + LK +V+ ++LS+N L+ + E+ L+KL L +P+E+ L +L T
Sbjct: 441 PKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLVRLQTI 500
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQFPSS 679
N K +PE + + L + + NNQ+ ++ P M M L +L+NN L Q P
Sbjct: 501 NLSFNRFKMLPEVLYRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPPE 560
Query: 680 ILKCKELMFLQLNSN 724
+ C L L L+ N
Sbjct: 561 LGNCVNLRTLLLDGN 575
Score = 61.7 bits (143), Expect = 3e-09
Identities = 43/176 (24%), Positives = 77/176 (43%), Gaps = 1/176 (0%)
Frame = +2
Query: 215 VEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVL 394
+E L L N ++ P P EI +K L +L+ + N L +
Sbjct: 176 LEDLDLSNNHLTTVPASFSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETI 235
Query: 395 IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI-PEEMTSLAKLRWL 571
PE+ +E LE + R L+ +P E + L N+++ + E + L + L
Sbjct: 236 PPELAGMESLELLYLRRNKLRFLP-EFPSCSLLKELHVGENQIEMLEAEHLKHLNSILVL 294
Query: 572 TLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSV 739
L +N+++++PD + + +L +L NN + P S L L FL L N + ++
Sbjct: 295 DLRDNKLKSVPDEIILLRSLERLDLSNNDISSLPYS-LGNLHLKFLALEGNPLRTI 349
Score = 57.2 bits (132), Expect = 7e-08
Identities = 35/122 (28%), Positives = 63/122 (51%), Gaps = 1/122 (0%)
Frame = +2
Query: 452 LKEIPKEIGKLTQL-DTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTA 628
L EIPK + +L ++ N+L I E+ L KL +L L NN + +LP+ M+ +
Sbjct: 437 LCEIPKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLVR 496
Query: 629 LVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPIC 808
L NL NR + P + + L + +++NQ+ SV ++ L +DL++N +
Sbjct: 497 LQTINLSFNRFKMLPEVLYRIFTLETILISNNQVGSVDPQ-KMKMMENLTTLDLQNNDLL 555
Query: 809 EL 814
++
Sbjct: 556 QI 557
Score = 44.4 bits (100), Expect = 5e-04
Identities = 25/105 (23%), Positives = 51/105 (48%)
Frame = +2
Query: 485 TQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLE 664
T L N+L+++ +++ L L L + +NQ+ +LP + + L N+ +N+L+
Sbjct: 82 TDLTKLIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLK 141
Query: 665 QFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSN 799
P I + L L L N+++ + + + L +DL +N
Sbjct: 142 ILPEEITNLRNLKCLYLQHNELTCISEGFEQ--LSNLEDLDLSNN 184
Score = 31.5 bits (68), Expect = 3.9
Identities = 22/80 (27%), Positives = 34/80 (42%), Gaps = 1/80 (1%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKI-SIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
LS N F++ +P +LY +E + + N++ S+ P + P
Sbjct: 502 LSFNRFKM--LPEVLYRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPP 559
Query: 332 EIGNLKNLVNLNLSYNPLNV 391
E+GN NL L L NP V
Sbjct: 560 ELGNCVNLRTLLLDGNPFRV 579
>BC003407-1|AAH03407.2| 581|Homo sapiens LRRC40 protein protein.
Length = 581
Score = 84.2 bits (199), Expect = 5e-16
Identities = 59/219 (26%), Positives = 106/219 (48%), Gaps = 1/219 (0%)
Frame = +2
Query: 152 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
+L+++ ++ +P + ++ LYL N+++ P
Sbjct: 111 KLNVSHNKLKILPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPA 170
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
+L +LV LNLS N L L EI +++L+ CN L+ IP E+ + L+ R
Sbjct: 171 SFSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLR 230
Query: 512 GNELKTIPEEMTSLAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQFPSSILK 688
N+L+ +PE S + L+ L + NQIE L + + + +++ +LR+N+L+ P I+
Sbjct: 231 RNKLRFLPE-FPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEIIL 289
Query: 689 CKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
+ L L L++N ISS+P +L L + L NP+
Sbjct: 290 LRSLERLDLSNNDISSLPYSLGNL---HLKFLALEGNPL 325
Score = 81.8 bits (193), Expect = 3e-15
Identities = 50/168 (29%), Positives = 83/168 (49%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P+ I L+NL LN+S+N L +L EI +L L+ + L I + +L+ L+
Sbjct: 100 PSAIRELENLQKLNVSHNKLKILPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLD 159
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
N L T+P +SL+ L L L +N++++LP ++RM L H + +N LE P +
Sbjct: 160 LSNNHLTTVPASFSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELA 219
Query: 686 KCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELSHPEH 829
+ L L L N++ +P SL+ L + + E H +H
Sbjct: 220 GMESLELLYLRRNKLRFLPEFPSCSLLKELH-VGENQIEMLEAEHLKH 266
Score = 77.4 bits (182), Expect = 6e-14
Identities = 50/154 (32%), Positives = 77/154 (50%)
Frame = +2
Query: 344 LKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNEL 523
L L L++ N L L I +LE L+ + LK +P+EI L L + NEL
Sbjct: 83 LPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKILPEEITNLRNLKCLYLQHNEL 142
Query: 524 KTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELM 703
I E L+ L L L NN + T+P + +++LV NL +N L+ P+ I + K L
Sbjct: 143 TCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRLNLSSNELKSLPAEINRMKRLK 202
Query: 704 FLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
L NSN + ++P L + + L ++ LR N +
Sbjct: 203 HLDCNSNLLETIPPEL--AGMESLELLYLRRNKL 234
Score = 73.3 bits (172), Expect = 1e-12
Identities = 47/159 (29%), Positives = 81/159 (50%)
Frame = +2
Query: 350 NLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKT 529
+L L +S N L L ++ L L + L +P I +L L N+LK
Sbjct: 62 DLTKLIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKI 121
Query: 530 IPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFL 709
+PEE+T+L L+ L L++N++ + + ++++ L +L NN L P+S L+ L
Sbjct: 122 LPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRL 181
Query: 710 QLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELSHPE 826
L+SN++ S+PA ++ + L +D SN + E PE
Sbjct: 182 NLSSNELKSLPAEINR--MKRLKHLDCNSN-LLETIPPE 217
Score = 64.5 bits (150), Expect = 4e-10
Identities = 41/135 (30%), Positives = 67/135 (49%), Gaps = 2/135 (1%)
Frame = +2
Query: 326 PTEIGNLKNLVN-LNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
P + LK +V+ ++LS+N L+ + E+ L+KL L +P+E+ L +L T
Sbjct: 420 PKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLVRLQTI 479
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQFPSS 679
N K +PE + + L + + NNQ+ ++ P M M L +L+NN L Q P
Sbjct: 480 NLSFNRFKMLPEVLYRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPPE 539
Query: 680 ILKCKELMFLQLNSN 724
+ C L L L+ N
Sbjct: 540 LGNCVNLRTLLLDGN 554
Score = 61.7 bits (143), Expect = 3e-09
Identities = 43/176 (24%), Positives = 77/176 (43%), Gaps = 1/176 (0%)
Frame = +2
Query: 215 VEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVL 394
+E L L N ++ P P EI +K L +L+ + N L +
Sbjct: 155 LEDLDLSNNHLTTVPASFSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETI 214
Query: 395 IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI-PEEMTSLAKLRWL 571
PE+ +E LE + R L+ +P E + L N+++ + E + L + L
Sbjct: 215 PPELAGMESLELLYLRRNKLRFLP-EFPSCSLLKELHVGENQIEMLEAEHLKHLNSILVL 273
Query: 572 TLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSV 739
L +N+++++PD + + +L +L NN + P S L L FL L N + ++
Sbjct: 274 DLRDNKLKSVPDEIILLRSLERLDLSNNDISSLPYS-LGNLHLKFLALEGNPLRTI 328
Score = 57.2 bits (132), Expect = 7e-08
Identities = 35/122 (28%), Positives = 63/122 (51%), Gaps = 1/122 (0%)
Frame = +2
Query: 452 LKEIPKEIGKLTQL-DTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTA 628
L EIPK + +L ++ N+L I E+ L KL +L L NN + +LP+ M+ +
Sbjct: 416 LCEIPKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLVR 475
Query: 629 LVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPIC 808
L NL NR + P + + L + +++NQ+ SV ++ L +DL++N +
Sbjct: 476 LQTINLSFNRFKMLPEVLYRIFTLETILISNNQVGSVDPQ-KMKMMENLTTLDLQNNDLL 534
Query: 809 EL 814
++
Sbjct: 535 QI 536
Score = 44.4 bits (100), Expect = 5e-04
Identities = 25/105 (23%), Positives = 51/105 (48%)
Frame = +2
Query: 485 TQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLE 664
T L N+L+++ +++ L L L + +NQ+ +LP + + L N+ +N+L+
Sbjct: 61 TDLTKLIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLK 120
Query: 665 QFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSN 799
P I + L L L N+++ + + + L +DL +N
Sbjct: 121 ILPEEITNLRNLKCLYLQHNELTCISEGFEQ--LSNLEDLDLSNN 163
Score = 31.5 bits (68), Expect = 3.9
Identities = 22/80 (27%), Positives = 34/80 (42%), Gaps = 1/80 (1%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKI-SIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
LS N F++ +P +LY +E + + N++ S+ P + P
Sbjct: 481 LSFNRFKM--LPEVLYRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPP 538
Query: 332 EIGNLKNLVNLNLSYNPLNV 391
E+GN NL L L NP V
Sbjct: 539 ELGNCVNLRTLLLDGNPFRV 558
>AY062238-1|AAL38976.1| 1630|Homo sapiens scribble protein.
Length = 1630
Score = 84.2 bits (199), Expect = 5e-16
Identities = 59/218 (27%), Positives = 95/218 (43%)
Frame = +2
Query: 152 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
+L L G ++ +P L + L+L +N++S P E P
Sbjct: 178 QLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSALPPELGNLRRLVCLDVSENRLEELPA 237
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
E+G L L +L LS N L L IG L++L ++ L E+ + IG L
Sbjct: 238 ELGGLVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEVTEAIGDCENLSELILT 297
Query: 512 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 691
N L +P + L KL L ++ N +E LP + AL +LR+NRL P +
Sbjct: 298 ENLLMALPRSLGKLTKLTNLNVDRNHLEALPPEIGGCVALSVLSLRDNRLAVLPPELAHT 357
Query: 692 KELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
EL L + N++ S+P L + L + + ++ P+
Sbjct: 358 TELHVLDVAGNRLQSLPFALTHLNLKALWLAENQAQPM 395
Score = 82.2 bits (194), Expect = 2e-15
Identities = 58/213 (27%), Positives = 93/213 (43%)
Frame = +2
Query: 176 ITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 355
+ +P L +++E L L N + + P P E+GNL+ L
Sbjct: 163 LKSLPASLSFLVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSALPPELGNLRRL 222
Query: 356 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 535
V L++S N L L E+G L L ++ L+ +P IG+L QL N L +
Sbjct: 223 VCLDVSENRLEELPAELGGLVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEVT 282
Query: 536 EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQL 715
E + L L L N + LP ++ ++T L + N+ N LE P I C L L L
Sbjct: 283 EAIGDCENLSELILTENLLMALPRSLGKLTKLTNLNVDRNHLEALPPEIGGCVALSVLSL 342
Query: 716 NSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
N+++ +P L + L ++D+ N + L
Sbjct: 343 RDNRLAVLPPEL--AHTTELHVLDVAGNRLQSL 373
Score = 77.8 bits (183), Expect = 5e-14
Identities = 53/222 (23%), Positives = 99/222 (44%)
Frame = +2
Query: 152 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
+L L+ EI +P + +++ L + +N I P P
Sbjct: 63 KLGLSDNEIQRLPPEVANFMQLVELDVSRNDIPEIPESIKFCKALEIADFSGNPLSRLPD 122
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
L++L +L L+ L L ++G+L L LK +P + L +L+
Sbjct: 123 GFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSLPASLSFLVKLEQLDLG 182
Query: 512 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 691
GN+L+ +P+ + +L LR L L+ NQ+ LP + + LV ++ NRLE+ P+ +
Sbjct: 183 GNDLEVLPDTLGALPNLRELWLDRNQLSALPPELGNLRRLVCLDVSENRLEELPAELGGL 242
Query: 692 KELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELS 817
L L L+ N + +P + + L ++ + N +CE++
Sbjct: 243 VLLTDLLLSQNLLRRLPDGI--GQLKQLSILKVDQNRLCEVT 282
Score = 67.7 bits (158), Expect = 5e-11
Identities = 48/163 (29%), Positives = 72/163 (44%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P L NL L LS N + L PE+ + +L +R + EIP+ I L+
Sbjct: 52 PKPFFRLLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDIPEIPESIKFCKALEIAD 111
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
GN L +P+ T L L L L + ++ LP + + LV LR N L+ P+S+
Sbjct: 112 FSGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSLPASLS 171
Query: 686 KCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
+L L L N + +P L +P L + L N + L
Sbjct: 172 FLVKLEQLDLGGNDLEVLPDTL--GALPNLRELWLDRNQLSAL 212
Score = 56.8 bits (131), Expect = 9e-08
Identities = 39/153 (25%), Positives = 64/153 (41%)
Frame = +2
Query: 347 KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELK 526
++L L L N L L L L + ++ +P E+ QL N++
Sbjct: 36 RSLEELLLDANQLRELPKPFFRLLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDIP 95
Query: 527 TIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMF 706
IPE + L N + LPD ++ +L H L + L+ P + L+
Sbjct: 96 EIPESIKFCKALEIADFSGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGDVGNLANLVT 155
Query: 707 LQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
L+L N + S+PA+L S + L +DL N +
Sbjct: 156 LELRENLLKSLPASL--SFLVKLEQLDLGGNDL 186
>AL353771-3|CAI22332.1| 602|Homo sapiens leucine rich repeat
containing 40 protein.
Length = 602
Score = 84.2 bits (199), Expect = 5e-16
Identities = 59/219 (26%), Positives = 106/219 (48%), Gaps = 1/219 (0%)
Frame = +2
Query: 152 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
+L+++ ++ +P + ++ LYL N+++ P
Sbjct: 132 KLNVSHNKLKILPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPA 191
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
+L +LV LNLS N L L EI +++L+ CN L+ IP E+ + L+ R
Sbjct: 192 SFSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLR 251
Query: 512 GNELKTIPEEMTSLAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQFPSSILK 688
N+L+ +PE S + L+ L + NQIE L + + + +++ +LR+N+L+ P I+
Sbjct: 252 RNKLRFLPE-FPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEIIL 310
Query: 689 CKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
+ L L L++N ISS+P +L L + L NP+
Sbjct: 311 LRSLERLDLSNNDISSLPYSLGNL---HLKFLALEGNPL 346
Score = 81.8 bits (193), Expect = 3e-15
Identities = 50/168 (29%), Positives = 83/168 (49%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P+ I L+NL LN+S+N L +L EI +L L+ + L I + +L+ L+
Sbjct: 121 PSAIRELENLQKLNVSHNKLKILPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLD 180
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
N L T+P +SL+ L L L +N++++LP ++RM L H + +N LE P +
Sbjct: 181 LSNNHLTTVPASFSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELA 240
Query: 686 KCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELSHPEH 829
+ L L L N++ +P SL+ L + + E H +H
Sbjct: 241 GMESLELLYLRRNKLRFLPEFPSCSLLKELH-VGENQIEMLEAEHLKH 287
Score = 77.4 bits (182), Expect = 6e-14
Identities = 50/154 (32%), Positives = 77/154 (50%)
Frame = +2
Query: 344 LKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNEL 523
L L L++ N L L I +LE L+ + LK +P+EI L L + NEL
Sbjct: 104 LPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKILPEEITNLRNLKCLYLQHNEL 163
Query: 524 KTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELM 703
I E L+ L L L NN + T+P + +++LV NL +N L+ P+ I + K L
Sbjct: 164 TCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRLNLSSNELKSLPAEINRMKRLK 223
Query: 704 FLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
L NSN + ++P L + + L ++ LR N +
Sbjct: 224 HLDCNSNLLETIPPEL--AGMESLELLYLRRNKL 255
Score = 73.3 bits (172), Expect = 1e-12
Identities = 47/159 (29%), Positives = 81/159 (50%)
Frame = +2
Query: 350 NLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKT 529
+L L +S N L L ++ L L + L +P I +L L N+LK
Sbjct: 83 DLTKLIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKI 142
Query: 530 IPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFL 709
+PEE+T+L L+ L L++N++ + + ++++ L +L NN L P+S L+ L
Sbjct: 143 LPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRL 202
Query: 710 QLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELSHPE 826
L+SN++ S+PA ++ + L +D SN + E PE
Sbjct: 203 NLSSNELKSLPAEINR--MKRLKHLDCNSN-LLETIPPE 238
Score = 64.5 bits (150), Expect = 4e-10
Identities = 41/135 (30%), Positives = 67/135 (49%), Gaps = 2/135 (1%)
Frame = +2
Query: 326 PTEIGNLKNLVN-LNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
P + LK +V+ ++LS+N L+ + E+ L+KL L +P+E+ L +L T
Sbjct: 441 PKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLVRLQTI 500
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQFPSS 679
N K +PE + + L + + NNQ+ ++ P M M L +L+NN L Q P
Sbjct: 501 NLSFNRFKMLPEVLYRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPPE 560
Query: 680 ILKCKELMFLQLNSN 724
+ C L L L+ N
Sbjct: 561 LGNCVNLRTLLLDGN 575
Score = 61.7 bits (143), Expect = 3e-09
Identities = 43/176 (24%), Positives = 77/176 (43%), Gaps = 1/176 (0%)
Frame = +2
Query: 215 VEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVL 394
+E L L N ++ P P EI +K L +L+ + N L +
Sbjct: 176 LEDLDLSNNHLTTVPASFSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETI 235
Query: 395 IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI-PEEMTSLAKLRWL 571
PE+ +E LE + R L+ +P E + L N+++ + E + L + L
Sbjct: 236 PPELAGMESLELLYLRRNKLRFLP-EFPSCSLLKELHVGENQIEMLEAEHLKHLNSILVL 294
Query: 572 TLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSV 739
L +N+++++PD + + +L +L NN + P S L L FL L N + ++
Sbjct: 295 DLRDNKLKSVPDEIILLRSLERLDLSNNDISSLPYS-LGNLHLKFLALEGNPLRTI 349
Score = 57.2 bits (132), Expect = 7e-08
Identities = 35/122 (28%), Positives = 63/122 (51%), Gaps = 1/122 (0%)
Frame = +2
Query: 452 LKEIPKEIGKLTQL-DTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTA 628
L EIPK + +L ++ N+L I E+ L KL +L L NN + +LP+ M+ +
Sbjct: 437 LCEIPKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLVR 496
Query: 629 LVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPIC 808
L NL NR + P + + L + +++NQ+ SV ++ L +DL++N +
Sbjct: 497 LQTINLSFNRFKMLPEVLYRIFTLETILISNNQVGSVDPQ-KMKMMENLTTLDLQNNDLL 555
Query: 809 EL 814
++
Sbjct: 556 QI 557
Score = 44.4 bits (100), Expect = 5e-04
Identities = 25/105 (23%), Positives = 51/105 (48%)
Frame = +2
Query: 485 TQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLE 664
T L N+L+++ +++ L L L + +NQ+ +LP + + L N+ +N+L+
Sbjct: 82 TDLTKLIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLK 141
Query: 665 QFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSN 799
P I + L L L N+++ + + + L +DL +N
Sbjct: 142 ILPEEITNLRNLKCLYLQHNELTCISEGFEQ--LSNLEDLDLSNN 184
Score = 31.5 bits (68), Expect = 3.9
Identities = 22/80 (27%), Positives = 34/80 (42%), Gaps = 1/80 (1%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKI-SIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
LS N F++ +P +LY +E + + N++ S+ P + P
Sbjct: 502 LSFNRFKM--LPEVLYRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPP 559
Query: 332 EIGNLKNLVNLNLSYNPLNV 391
E+GN NL L L NP V
Sbjct: 560 ELGNCVNLRTLLLDGNPFRV 579
>AK022951-1|BAB14326.1| 602|Homo sapiens protein ( Homo sapiens
cDNA FLJ12889 fis, clone NT2RP2004098, weakly similar to
ADENYLATE CYCLASE (EC 4.6.1.1). ).
Length = 602
Score = 84.2 bits (199), Expect = 5e-16
Identities = 59/219 (26%), Positives = 106/219 (48%), Gaps = 1/219 (0%)
Frame = +2
Query: 152 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
+L+++ ++ +P + ++ LYL N+++ P
Sbjct: 132 KLNVSHNKLKILPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPA 191
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
+L +LV LNLS N L L EI +++L+ CN L+ IP E+ + L+ R
Sbjct: 192 SFSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLR 251
Query: 512 GNELKTIPEEMTSLAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQFPSSILK 688
N+L+ +PE S + L+ L + NQIE L + + + +++ +LR+N+L+ P I+
Sbjct: 252 RNKLRFLPE-FPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEIIL 310
Query: 689 CKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
+ L L L++N ISS+P +L L + L NP+
Sbjct: 311 LRSLERLDLSNNDISSLPYSLGNL---HLKFLALEGNPL 346
Score = 81.8 bits (193), Expect = 3e-15
Identities = 50/168 (29%), Positives = 83/168 (49%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P+ I L+NL LN+S+N L +L EI +L L+ + L I + +L+ L+
Sbjct: 121 PSAIRELENLQKLNVSHNKLKILPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLD 180
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
N L T+P +SL+ L L L +N++++LP ++RM L H + +N LE P +
Sbjct: 181 LSNNHLTTVPASFSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELA 240
Query: 686 KCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELSHPEH 829
+ L L L N++ +P SL+ L + + E H +H
Sbjct: 241 GMESLELLYLRRNKLRFLPEFPSCSLLKELH-VGENQIEMLEAEHLKH 287
Score = 77.4 bits (182), Expect = 6e-14
Identities = 50/154 (32%), Positives = 77/154 (50%)
Frame = +2
Query: 344 LKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNEL 523
L L L++ N L L I +LE L+ + LK +P+EI L L + NEL
Sbjct: 104 LPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKILPEEITNLRNLKCLYLQHNEL 163
Query: 524 KTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELM 703
I E L+ L L L NN + T+P + +++LV NL +N L+ P+ I + K L
Sbjct: 164 TCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRLNLSSNELKSLPAEINRMKRLK 223
Query: 704 FLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
L NSN + ++P L + + L ++ LR N +
Sbjct: 224 HLDCNSNLLETIPPEL--AGMESLELLYLRRNKL 255
Score = 73.3 bits (172), Expect = 1e-12
Identities = 47/159 (29%), Positives = 81/159 (50%)
Frame = +2
Query: 350 NLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKT 529
+L L +S N L L ++ L L + L +P I +L L N+LK
Sbjct: 83 DLTKLIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKI 142
Query: 530 IPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFL 709
+PEE+T+L L+ L L++N++ + + ++++ L +L NN L P+S L+ L
Sbjct: 143 LPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRL 202
Query: 710 QLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELSHPE 826
L+SN++ S+PA ++ + L +D SN + E PE
Sbjct: 203 NLSSNELKSLPAEINR--MKRLKHLDCNSN-LLETIPPE 238
Score = 64.5 bits (150), Expect = 4e-10
Identities = 41/135 (30%), Positives = 67/135 (49%), Gaps = 2/135 (1%)
Frame = +2
Query: 326 PTEIGNLKNLVN-LNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
P + LK +V+ ++LS+N L+ + E+ L+KL L +P+E+ L +L T
Sbjct: 441 PKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLVRLQTI 500
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQFPSS 679
N K +PE + + L + + NNQ+ ++ P M M L +L+NN L Q P
Sbjct: 501 NLSFNRFKMLPEVLYRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPPE 560
Query: 680 ILKCKELMFLQLNSN 724
+ C L L L+ N
Sbjct: 561 LGNCVNLRTLLLDGN 575
Score = 61.7 bits (143), Expect = 3e-09
Identities = 43/176 (24%), Positives = 77/176 (43%), Gaps = 1/176 (0%)
Frame = +2
Query: 215 VEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVL 394
+E L L N ++ P P EI +K L +L+ + N L +
Sbjct: 176 LEDLDLSNNHLTTVPASFSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETI 235
Query: 395 IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI-PEEMTSLAKLRWL 571
PE+ +E LE + R L+ +P E + L N+++ + E + L + L
Sbjct: 236 PPELAGMESLELLYLRRNKLRFLP-EFPSCSLLKELHVGENQIEMLEAEHLKHLNSILVL 294
Query: 572 TLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSV 739
L +N+++++PD + + +L +L NN + P S L L FL L N + ++
Sbjct: 295 DLRDNKLKSVPDEIILLRSLERLDLSNNDISSLPYS-LGNLHLKFLALEGNPLRTI 349
Score = 57.2 bits (132), Expect = 7e-08
Identities = 35/122 (28%), Positives = 63/122 (51%), Gaps = 1/122 (0%)
Frame = +2
Query: 452 LKEIPKEIGKLTQL-DTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTA 628
L EIPK + +L ++ N+L I E+ L KL +L L NN + +LP+ M+ +
Sbjct: 437 LCEIPKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLVR 496
Query: 629 LVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPIC 808
L NL NR + P + + L + +++NQ+ SV ++ L +DL++N +
Sbjct: 497 LQTINLSFNRFKMLPEVLYRIFTLETILISNNQVGSVDPQ-KMKMMENLTTLDLQNNDLL 555
Query: 809 EL 814
++
Sbjct: 556 QI 557
Score = 44.4 bits (100), Expect = 5e-04
Identities = 25/105 (23%), Positives = 51/105 (48%)
Frame = +2
Query: 485 TQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLE 664
T L N+L+++ +++ L L L + +NQ+ +LP + + L N+ +N+L+
Sbjct: 82 TDLTKLIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLK 141
Query: 665 QFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSN 799
P I + L L L N+++ + + + L +DL +N
Sbjct: 142 ILPEEITNLRNLKCLYLQHNELTCISEGFEQ--LSNLEDLDLSNN 184
Score = 31.5 bits (68), Expect = 3.9
Identities = 22/80 (27%), Positives = 34/80 (42%), Gaps = 1/80 (1%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKI-SIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
LS N F++ +P +LY +E + + N++ S+ P + P
Sbjct: 502 LSFNRFKM--LPEVLYRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPP 559
Query: 332 EIGNLKNLVNLNLSYNPLNV 391
E+GN NL L L NP V
Sbjct: 560 ELGNCVNLRTLLLDGNPFRV 579
>AF271734-1|AAP88018.1| 1601|Homo sapiens SCRIB1 variant N1 protein.
Length = 1601
Score = 84.2 bits (199), Expect = 5e-16
Identities = 59/218 (27%), Positives = 95/218 (43%)
Frame = +2
Query: 152 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
+L L G ++ +P L + L+L +N++S P E P
Sbjct: 149 QLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSALPPELGNLRRLVCLDVSENRLEELPA 208
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
E+G L L +L LS N L L IG L++L ++ L E+ + IG L
Sbjct: 209 ELGGLVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEVTEAIGDCENLSELILT 268
Query: 512 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 691
N L +P + L KL L ++ N +E LP + AL +LR+NRL P +
Sbjct: 269 ENLLMALPRSLGKLTKLTNLNVDRNHLEALPPEIGGCVALSVLSLRDNRLAVLPPELAHT 328
Query: 692 KELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
EL L + N++ S+P L + L + + ++ P+
Sbjct: 329 TELHVLDVAGNRLQSLPFALTHLNLKALWLAENQAQPM 366
Score = 82.2 bits (194), Expect = 2e-15
Identities = 58/213 (27%), Positives = 93/213 (43%)
Frame = +2
Query: 176 ITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 355
+ +P L +++E L L N + + P P E+GNL+ L
Sbjct: 134 LKSLPASLSFLVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSALPPELGNLRRL 193
Query: 356 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 535
V L++S N L L E+G L L ++ L+ +P IG+L QL N L +
Sbjct: 194 VCLDVSENRLEELPAELGGLVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEVT 253
Query: 536 EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQL 715
E + L L L N + LP ++ ++T L + N+ N LE P I C L L L
Sbjct: 254 EAIGDCENLSELILTENLLMALPRSLGKLTKLTNLNVDRNHLEALPPEIGGCVALSVLSL 313
Query: 716 NSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
N+++ +P L + L ++D+ N + L
Sbjct: 314 RDNRLAVLPPEL--AHTTELHVLDVAGNRLQSL 344
Score = 77.8 bits (183), Expect = 5e-14
Identities = 53/222 (23%), Positives = 99/222 (44%)
Frame = +2
Query: 152 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
+L L+ EI +P + +++ L + +N I P P
Sbjct: 34 KLGLSDNEIQRLPPEVANFMQLVELDVSRNDIPEIPESIKFCKALEIADFSGNPLSRLPD 93
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
L++L +L L+ L L ++G+L L LK +P + L +L+
Sbjct: 94 GFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSLPASLSFLVKLEQLDLG 153
Query: 512 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 691
GN+L+ +P+ + +L LR L L+ NQ+ LP + + LV ++ NRLE+ P+ +
Sbjct: 154 GNDLEVLPDTLGALPNLRELWLDRNQLSALPPELGNLRRLVCLDVSENRLEELPAELGGL 213
Query: 692 KELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELS 817
L L L+ N + +P + + L ++ + N +CE++
Sbjct: 214 VLLTDLLLSQNLLRRLPDGI--GQLKQLSILKVDQNRLCEVT 253
Score = 66.9 bits (156), Expect = 8e-11
Identities = 47/157 (29%), Positives = 71/157 (45%)
Frame = +2
Query: 344 LKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNEL 523
L NL L LS N + L PE+ + +L +R + EIP+ I L+ GN L
Sbjct: 29 LLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDIPEIPESIKFCKALEIADFSGNPL 88
Query: 524 KTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELM 703
+P+ T L L L L + ++ LP + + LV LR N L+ P+S+ +L
Sbjct: 89 SRLPDGFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSLPASLSFLVKLE 148
Query: 704 FLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
L L N + +P L +P L + L N + L
Sbjct: 149 QLDLGGNDLEVLPDTL--GALPNLRELWLDRNQLSAL 183
>AF240677-1|AAP88017.1| 1630|Homo sapiens CRIB1 protein.
Length = 1630
Score = 84.2 bits (199), Expect = 5e-16
Identities = 59/218 (27%), Positives = 95/218 (43%)
Frame = +2
Query: 152 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
+L L G ++ +P L + L+L +N++S P E P
Sbjct: 178 QLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSALPPELGNLRRLVCLDVSENRLEELPA 237
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
E+G L L +L LS N L L IG L++L ++ L E+ + IG L
Sbjct: 238 ELGGLVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEVTEAIGDCENLSELILT 297
Query: 512 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 691
N L +P + L KL L ++ N +E LP + AL +LR+NRL P +
Sbjct: 298 ENLLMALPRSLGKLTKLTNLNVDRNHLEALPPEIGGCVALSVLSLRDNRLAVLPPELAHT 357
Query: 692 KELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
EL L + N++ S+P L + L + + ++ P+
Sbjct: 358 TELHVLDVAGNRLQSLPFALTHLNLKALWLAENQAQPM 395
Score = 82.2 bits (194), Expect = 2e-15
Identities = 58/213 (27%), Positives = 93/213 (43%)
Frame = +2
Query: 176 ITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 355
+ +P L +++E L L N + + P P E+GNL+ L
Sbjct: 163 LKSLPASLSFLVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSALPPELGNLRRL 222
Query: 356 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 535
V L++S N L L E+G L L ++ L+ +P IG+L QL N L +
Sbjct: 223 VCLDVSENRLEELPAELGGLVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEVT 282
Query: 536 EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQL 715
E + L L L N + LP ++ ++T L + N+ N LE P I C L L L
Sbjct: 283 EAIGDCENLSELILTENLLMALPRSLGKLTKLTNLNVDRNHLEALPPEIGGCVALSVLSL 342
Query: 716 NSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
N+++ +P L + L ++D+ N + L
Sbjct: 343 RDNRLAVLPPEL--AHTTELHVLDVAGNRLQSL 373
Score = 77.8 bits (183), Expect = 5e-14
Identities = 53/222 (23%), Positives = 99/222 (44%)
Frame = +2
Query: 152 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
+L L+ EI +P + +++ L + +N I P P
Sbjct: 63 KLGLSDNEIQRLPPEVANFMQLVELDVSRNDIPEIPESIKFCKALEIADFSGNPLSRLPD 122
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
L++L +L L+ L L ++G+L L LK +P + L +L+
Sbjct: 123 GFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSLPASLSFLVKLEQLDLG 182
Query: 512 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 691
GN+L+ +P+ + +L LR L L+ NQ+ LP + + LV ++ NRLE+ P+ +
Sbjct: 183 GNDLEVLPDTLGALPNLRELWLDRNQLSALPPELGNLRRLVCLDVSENRLEELPAELGGL 242
Query: 692 KELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELS 817
L L L+ N + +P + + L ++ + N +CE++
Sbjct: 243 VLLTDLLLSQNLLRRLPDGI--GQLKQLSILKVDQNRLCEVT 282
Score = 67.7 bits (158), Expect = 5e-11
Identities = 48/163 (29%), Positives = 72/163 (44%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P L NL L LS N + L PE+ + +L +R + EIP+ I L+
Sbjct: 52 PKPFFRLLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDIPEIPESIKFCKALEIAD 111
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
GN L +P+ T L L L L + ++ LP + + LV LR N L+ P+S+
Sbjct: 112 FSGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSLPASLS 171
Query: 686 KCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
+L L L N + +P L +P L + L N + L
Sbjct: 172 FLVKLEQLDLGGNDLEVLPDTL--GALPNLRELWLDRNQLSAL 212
Score = 56.8 bits (131), Expect = 9e-08
Identities = 39/153 (25%), Positives = 64/153 (41%)
Frame = +2
Query: 347 KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELK 526
++L L L N L L L L + ++ +P E+ QL N++
Sbjct: 36 RSLEELLLDANQLRELPKPFFRLLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDIP 95
Query: 527 TIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMF 706
IPE + L N + LPD ++ +L H L + L+ P + L+
Sbjct: 96 EIPESIKFCKALEIADFSGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGDVGNLANLVT 155
Query: 707 LQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
L+L N + S+PA+L S + L +DL N +
Sbjct: 156 LELRENLLKSLPASL--SFLVKLEQLDLGGNDL 186
>BC009613-1|AAH09613.1| 335|Homo sapiens leucine rich repeat
containing 39 protein.
Length = 335
Score = 83.0 bits (196), Expect = 1e-15
Identities = 59/220 (26%), Positives = 100/220 (45%), Gaps = 3/220 (1%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L + E +P L +++ LH+ + P P
Sbjct: 65 LKIEKEEWKTLPSSLLKLNQLQEWQLHRTGLLKIPEFIGRFQNLIVLDLSRNTISEIPPG 124
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGD---LEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
IG L L L LSYN + + E+ + LEKLE NR + ++P+E+ L +L
Sbjct: 125 IGLLTRLQELILSYNKIKTVPKELSNCASLEKLELA-VNR-DICDLPQELSNLLKLTHLD 182
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
N+ TIP + ++ L WL + +N++E LPDT++RM L L+ N + P +I
Sbjct: 183 LSMNDFTTIPLAVLNMPALEWLDMGSNKLEQLPDTIERMQNLHTLWLQRNEITCLPQTIS 242
Query: 686 KCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
K L L L++N++ +P ++ + L ++ R NP+
Sbjct: 243 NMKNLGTLVLSNNKLQDIPVCMEE--MANLRFVNFRDNPL 280
Score = 66.9 bits (156), Expect = 8e-11
Identities = 45/171 (26%), Positives = 77/171 (45%), Gaps = 1/171 (0%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXX-XXPT 331
L L+ I+EIP + ++ L L NKI P E P
Sbjct: 111 LDLSRNTISEIPPGIGLLTRLQELILSYNKIKTVPKELSNCASLEKLELAVNRDICDLPQ 170
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
E+ NL L +L+LS N + + ++ LE L+++P I ++ L T +
Sbjct: 171 ELSNLLKLTHLDLSMNDFTTIPLAVLNMPALEWLDMGSNKLEQLPDTIERMQNLHTLWLQ 230
Query: 512 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLE 664
NE+ +P+ ++++ L L L NN+++ +P M+ M L N R+N L+
Sbjct: 231 RNEITCLPQTISNMKNLGTLVLSNNKLQDIPVCMEEMANLRFVNFRDNPLK 281
>AY358131-1|AAQ88498.1| 335|Homo sapiens densin hlg protein.
Length = 335
Score = 83.0 bits (196), Expect = 1e-15
Identities = 59/220 (26%), Positives = 100/220 (45%), Gaps = 3/220 (1%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L + E +P L +++ LH+ + P P
Sbjct: 65 LKIEKEEWKTLPSSLLKLNQLQEWQLHRTGLLKIPEFIGRFQNLIVLDLSRNTISEIPPG 124
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGD---LEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
IG L L L LSYN + + E+ + LEKLE NR + ++P+E+ L +L
Sbjct: 125 IGLLTRLQELILSYNKIKTVPKELSNCASLEKLELA-VNR-DICDLPQELSNLLKLTHLD 182
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
N+ TIP + ++ L WL + +N++E LPDT++RM L L+ N + P +I
Sbjct: 183 LSMNDFTTIPLAVLNMPALEWLDMGSNKLEQLPDTIERMQNLHTLWLQRNEITCLPQTIS 242
Query: 686 KCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
K L L L++N++ +P ++ + L ++ R NP+
Sbjct: 243 NMKNLGTLVLSNNKLQDIPVCMEE--MANLRFVNFRDNPL 280
Score = 66.9 bits (156), Expect = 8e-11
Identities = 45/171 (26%), Positives = 77/171 (45%), Gaps = 1/171 (0%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXX-XXPT 331
L L+ I+EIP + ++ L L NKI P E P
Sbjct: 111 LDLSRNTISEIPPGIGLLTRLQELILSYNKIKTVPKELSNCASLEKLELAVNRDICDLPQ 170
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
E+ NL L +L+LS N + + ++ LE L+++P I ++ L T +
Sbjct: 171 ELSNLLKLTHLDLSMNDFTTIPLAVLNMPALEWLDMGSNKLEQLPDTIERMQNLHTLWLQ 230
Query: 512 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLE 664
NE+ +P+ ++++ L L L NN+++ +P M+ M L N R+N L+
Sbjct: 231 RNEITCLPQTISNMKNLGTLVLSNNKLQDIPVCMEEMANLRFVNFRDNPLK 281
>AL445928-6|CAH72254.1| 339|Homo sapiens leucine rich repeat
containing 39 protein.
Length = 339
Score = 83.0 bits (196), Expect = 1e-15
Identities = 59/220 (26%), Positives = 100/220 (45%), Gaps = 3/220 (1%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L + E +P L +++ LH+ + P P
Sbjct: 65 LKIEKEEWKTLPSSLLKLNQLQEWQLHRTGLLKIPEFIGRFQNLIVLDLSRNTISEIPPG 124
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGD---LEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
IG L L L LSYN + + E+ + LEKLE NR + ++P+E+ L +L
Sbjct: 125 IGLLTRLQELILSYNKIKTVPKELSNCASLEKLELA-VNR-DICDLPQELSNLLKLTHLD 182
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
N+ TIP + ++ L WL + +N++E LPDT++RM L L+ N + P +I
Sbjct: 183 LSMNDFTTIPLAVLNMPALEWLDMGSNKLEQLPDTIERMQNLHTLWLQRNEITCLPQTIS 242
Query: 686 KCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
K L L L++N++ +P ++ + L ++ R NP+
Sbjct: 243 NMKNLGTLVLSNNKLQDIPVCMEE--MANLRFVNFRDNPL 280
Score = 66.9 bits (156), Expect = 8e-11
Identities = 45/171 (26%), Positives = 77/171 (45%), Gaps = 1/171 (0%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXX-XXPT 331
L L+ I+EIP + ++ L L NKI P E P
Sbjct: 111 LDLSRNTISEIPPGIGLLTRLQELILSYNKIKTVPKELSNCASLEKLELAVNRDICDLPQ 170
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
E+ NL L +L+LS N + + ++ LE L+++P I ++ L T +
Sbjct: 171 ELSNLLKLTHLDLSMNDFTTIPLAVLNMPALEWLDMGSNKLEQLPDTIERMQNLHTLWLQ 230
Query: 512 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLE 664
NE+ +P+ ++++ L L L NN+++ +P M+ M L N R+N L+
Sbjct: 231 RNEITCLPQTISNMKNLGTLVLSNNKLQDIPVCMEEMANLRFVNFRDNPLK 281
>AL445928-5|CAH72253.1| 335|Homo sapiens leucine rich repeat
containing 39 protein.
Length = 335
Score = 83.0 bits (196), Expect = 1e-15
Identities = 59/220 (26%), Positives = 100/220 (45%), Gaps = 3/220 (1%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L + E +P L +++ LH+ + P P
Sbjct: 65 LKIEKEEWKTLPSSLLKLNQLQEWQLHRTGLLKIPEFIGRFQNLIVLDLSRNTISEIPPG 124
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGD---LEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
IG L L L LSYN + + E+ + LEKLE NR + ++P+E+ L +L
Sbjct: 125 IGLLTRLQELILSYNKIKTVPKELSNCASLEKLELA-VNR-DICDLPQELSNLLKLTHLD 182
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
N+ TIP + ++ L WL + +N++E LPDT++RM L L+ N + P +I
Sbjct: 183 LSMNDFTTIPLAVLNMPALEWLDMGSNKLEQLPDTIERMQNLHTLWLQRNEITCLPQTIS 242
Query: 686 KCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
K L L L++N++ +P ++ + L ++ R NP+
Sbjct: 243 NMKNLGTLVLSNNKLQDIPVCMEE--MANLRFVNFRDNPL 280
Score = 66.9 bits (156), Expect = 8e-11
Identities = 45/171 (26%), Positives = 77/171 (45%), Gaps = 1/171 (0%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXX-XXPT 331
L L+ I+EIP + ++ L L NKI P E P
Sbjct: 111 LDLSRNTISEIPPGIGLLTRLQELILSYNKIKTVPKELSNCASLEKLELAVNRDICDLPQ 170
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
E+ NL L +L+LS N + + ++ LE L+++P I ++ L T +
Sbjct: 171 ELSNLLKLTHLDLSMNDFTTIPLAVLNMPALEWLDMGSNKLEQLPDTIERMQNLHTLWLQ 230
Query: 512 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLE 664
NE+ +P+ ++++ L L L NN+++ +P M+ M L N R+N L+
Sbjct: 231 RNEITCLPQTISNMKNLGTLVLSNNKLQDIPVCMEEMANLRFVNFRDNPLK 281
>AL158163-3|CAH72813.1| 372|Homo sapiens soc-2 suppressor of clear
homolog (C. elegans) protein.
Length = 372
Score = 81.4 bits (192), Expect = 4e-15
Identities = 51/164 (31%), Positives = 81/164 (49%), Gaps = 1/164 (0%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P + G ++V LNL+ N L + ++ L LE + LK++P +G L +L
Sbjct: 185 PLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELD 244
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
N+L+++P E+ L L+ L L NNQ+ TLP + +T L H L N L P I
Sbjct: 245 LEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIG 304
Query: 686 KCKELMFLQLNSN-QISSVPANLDTSLVPGLXMIDLRSNPICEL 814
+ L L LN N + S+P L +L L ++ + + P+ L
Sbjct: 305 TLENLEELYLNDNPNLHSLPFEL--ALCSKLSIMSIENCPLSHL 346
Score = 79.0 bits (186), Expect = 2e-14
Identities = 42/121 (34%), Positives = 69/121 (57%)
Frame = +2
Query: 404 IGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLEN 583
+ +L+KL L+EIP + +L L T R N + T+ +++ +L+KL L++
Sbjct: 1 LDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRE 60
Query: 584 NQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSL 763
N+I+ LP + +++L LR NRL P S+ KC L L L +N IS++P +L +SL
Sbjct: 61 NKIKQLPAEIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSL 120
Query: 764 V 766
V
Sbjct: 121 V 121
Score = 74.1 bits (174), Expect = 6e-13
Identities = 55/205 (26%), Positives = 86/205 (41%), Gaps = 4/205 (1%)
Frame = +2
Query: 149 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXP 328
SRL L ++ IP L C +E L L N IS P E
Sbjct: 77 SRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLP-ESLLSSLVKLNSLTLARNCFQL 135
Query: 329 TEIGN---LKNLVNLNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLD 496
+G + +LN+ +N +N + I K L L +P + G T +
Sbjct: 136 YPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMV 195
Query: 497 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 676
N+L IPE+++ L L L L NN ++ LP + + L +L N+LE P+
Sbjct: 196 ELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPN 255
Query: 677 SILKCKELMFLQLNSNQISSVPANL 751
I K+L L L +NQ++++P +
Sbjct: 256 EIAYLKDLQKLVLTNNQLTTLPRGI 280
Score = 72.5 bits (170), Expect = 2e-12
Identities = 45/165 (27%), Positives = 77/165 (46%), Gaps = 2/165 (1%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P+ + L +L L L +N + + +I +L KL +K++P EIG L+ L G
Sbjct: 21 PSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGNLSSLSRLG 80
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDT-MDRMTALVHCNLRNNRLEQFP-SS 679
R N L IP + + L L LENN I TLP++ + + L L N + +P
Sbjct: 81 LRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGG 140
Query: 680 ILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
+ + L + N+I+ +P + S L ++++ N + L
Sbjct: 141 PSQFSTIYSLNMEHNRINKIPFGI-FSRAKVLSKLNMKDNQLTSL 184
Score = 68.5 bits (160), Expect = 3e-11
Identities = 54/225 (24%), Positives = 96/225 (42%), Gaps = 3/225 (1%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L ++ EIP ++Y + LYL N+I+ + P E
Sbjct: 10 LDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAE 69
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKE-IGKLTQLDTFGAR 511
IGNL +L L L YN L+ + + LE + +P+ + L +L++
Sbjct: 70 IGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLA 129
Query: 512 GNELKTIPEEMTS-LAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQFPSSIL 685
N + P S + + L +E+N+I +P R L N+++N+L P
Sbjct: 130 RNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFG 189
Query: 686 KCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELSH 820
++ L L +NQ++ +P D S + L ++ L +N + +L H
Sbjct: 190 TWTSMVELNLATNQLTKIPE--DVSGLVSLEVLILSNNLLKKLPH 232
Score = 62.9 bits (146), Expect = 1e-09
Identities = 47/201 (23%), Positives = 81/201 (40%), Gaps = 2/201 (0%)
Frame = +2
Query: 155 LSLNGFEITEIP-GLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
L++ I +IP G+ + L + N+++ P++ P
Sbjct: 150 LNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPE 209
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
++ L +L L LS N L L +G+L KL L+ +P EI L L
Sbjct: 210 DVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLT 269
Query: 512 GNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNN-RLEQFPSSILK 688
N+L T+P + L L L L N + LP+ + + L L +N L P +
Sbjct: 270 NNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNLHSLPFELAL 329
Query: 689 CKELMFLQLNSNQISSVPANL 751
C +L + + + +S +P +
Sbjct: 330 CSKLSIMSIENCPLSHLPPQI 350
>AF229178-1|AAF69491.1| 753|Homo sapiens leucine rich repeat and
death domain containing protein protein.
Length = 753
Score = 80.2 bits (189), Expect = 8e-15
Identities = 43/121 (35%), Positives = 71/121 (58%)
Frame = +2
Query: 452 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 631
L E+P+ +G L L N L+T+P + +L+ L+ L L N ++TLP + + +L
Sbjct: 14 LSELPEALGALPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLLDTLPPEIGGLGSL 73
Query: 632 VHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICE 811
+ NL +NRL+ P+S+ + L L L+SN ++SVPA D + +P L +DLR N + +
Sbjct: 74 LELNLASNRLQSLPASLAGLRSLRLLVLHSNLLASVPA--DLARLPLLTRLDLRDNQLRD 131
Query: 812 L 814
L
Sbjct: 132 L 132
Score = 60.1 bits (139), Expect = 1e-08
Identities = 44/158 (27%), Positives = 74/158 (46%)
Frame = +2
Query: 344 LKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNEL 523
++ L L LS+N L+ L +G L L L+ +P +G L+ L N L
Sbjct: 1 MRGLGALLLSHNCLSELPEALGALPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLL 60
Query: 524 KTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELM 703
T+P E+ L L L L +N++++LP ++ + +L L +N L P+ + + L
Sbjct: 61 DTLPPEIGGLGSLLELNLASNRLQSLPASLAGLRSLRLLVLHSNLLASVPADLARLPLLT 120
Query: 704 FLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELS 817
L L NQ+ +P L + + L+ NP+ E S
Sbjct: 121 RLDLRDNQLRDLPPELLDA-----PFVRLQGNPLGEAS 153
Score = 46.8 bits (106), Expect = 1e-04
Identities = 35/145 (24%), Positives = 58/145 (40%), Gaps = 1/145 (0%)
Frame = +2
Query: 176 ITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 355
++E+P L + L + N++ P P EIG L +L
Sbjct: 14 LSELPEALGALPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLLDTLPPEIGGLGSL 73
Query: 356 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 535
+ LNL+ N L L + L L + L +P ++ +L L R N+L+ +P
Sbjct: 74 LELNLASNRLQSLPASLAGLRSLRLLVLHSNLLASVPADLARLPLLTRLDLRDNQLRDLP 133
Query: 536 EEMTSLAKLRWLTLENNQI-ETLPD 607
E+ +R L+ N + E PD
Sbjct: 134 PELLDAPFVR---LQGNPLGEASPD 155
>BC125224-1|AAI25225.1| 748|Homo sapiens LRCH2 protein protein.
Length = 748
Score = 79.4 bits (187), Expect = 1e-14
Identities = 55/199 (27%), Positives = 89/199 (44%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
LSL+G ++ + PG Y + L +N+ + P + P
Sbjct: 93 LSLSGRKLRDFPGSGYDLTDTTQADLSRNRFTEIPSDVWLFAPLETLNLYHNCIKTIPEA 152
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
I NL+ L LN+S N L+ L + DL L+ + L IP+EIGKL L
Sbjct: 153 IKNLQMLTYLNISRNLLSTLPKYLFDLP-LKVLVVSNNKLVSIPEEIGKLKDLMELDISC 211
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
NE++ +P++M L LR L + N + LPD + + LV + N++ + P K
Sbjct: 212 NEIQVLPQQMGKLHSLRELNIRRNNLHVLPDELGDL-PLVKLDFSCNKVTEIPVCYRKLH 270
Query: 695 ELMFLQLNSNQISSVPANL 751
L + L++N + PA +
Sbjct: 271 HLQVIILDNNPLQVPPAQI 289
>BC018529-1|AAH18529.3| 683|Homo sapiens leucine-rich repeats and
calponin homology (CH) domain containing 4 protein.
Length = 683
Score = 79.4 bits (187), Expect = 1e-14
Identities = 48/139 (34%), Positives = 73/139 (52%)
Frame = +2
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
+GNL L LNLS N L++L P I L L + L +P +IG L L
Sbjct: 110 LGNLTALTYLNLSRNQLSLLPPYICQLP-LRVLIVSNNKLGALPPDIGTLGSLRQLDVSS 168
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
NEL+++P E+ L+ LR L + NQ+ TLP+ + + LV + NR+ + P S + +
Sbjct: 169 NELQSLPSELCGLSSLRDLNVRRNQLSTLPEELGDL-PLVRLDFSCNRVSRIPVSFCRLR 227
Query: 695 ELMFLQLNSNQISSVPANL 751
L + L+SN + S PA +
Sbjct: 228 HLQVILLDSNPLQSPPAQV 246
Score = 46.4 bits (105), Expect = 1e-04
Identities = 31/115 (26%), Positives = 56/115 (48%)
Frame = +2
Query: 470 EIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLR 649
++ +TQ D N +PE L L L+L +N + L + +TAL + NL
Sbjct: 66 DLSDITQADL---SRNRFPEVPEAACQLVSLEGLSLYHNCLRCLNPALGNLTALTYLNLS 122
Query: 650 NNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
N+L P I + L L +++N++ ++P ++ T + L +D+ SN + L
Sbjct: 123 RNQLSLLPPYICQL-PLRVLIVSNNKLGALPPDIGT--LGSLRQLDVSSNELQSL 174
Score = 45.2 bits (102), Expect = 3e-04
Identities = 39/150 (26%), Positives = 66/150 (44%), Gaps = 5/150 (3%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTC-LEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
L+L+ +++ +P Y C L + L + NK+ P + P+
Sbjct: 119 LNLSRNQLSLLPP--YICQLPLRVLIVSNNKLGALPPDIGTLGSLRQLDVSSNELQSLPS 176
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEA-FWCNRIGLKEIPKEIGKLTQLDTFGA 508
E+ L +L +LN+ N L+ L E+GDL + F CNR+ IP +L L
Sbjct: 177 ELCGLSSLRDLNVRRNQLSTLPEELGDLPLVRLDFSCNRV--SRIPVSFCRLRHLQVILL 234
Query: 509 RGNELKTIPEEMTSLAKL---RWLTLENNQ 589
N L++ P ++ KL ++L+ E Q
Sbjct: 235 DSNPLQSPPAQVCLKGKLHIFKYLSTEAGQ 264
>BC007634-1|AAH07634.1| 580|Homo sapiens LRCH4 protein protein.
Length = 580
Score = 79.4 bits (187), Expect = 1e-14
Identities = 48/139 (34%), Positives = 73/139 (52%)
Frame = +2
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
+GNL L LNLS N L++L P I L L + L +P +IG L L
Sbjct: 7 LGNLTALTYLNLSRNQLSLLPPYICQLP-LRVLIVSNNKLGALPPDIGTLGSLRQLDVSS 65
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
NEL+++P E+ L+ LR L + NQ+ TLP+ + + LV + NR+ + P S + +
Sbjct: 66 NELQSLPSELCGLSSLRDLNVRRNQLSTLPEELGDL-PLVRLDFSCNRVSRIPVSFCRLR 124
Query: 695 ELMFLQLNSNQISSVPANL 751
L + L+SN + S PA +
Sbjct: 125 HLQVILLDSNPLQSPPAQV 143
Score = 45.2 bits (102), Expect = 3e-04
Identities = 39/150 (26%), Positives = 66/150 (44%), Gaps = 5/150 (3%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTC-LEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
L+L+ +++ +P Y C L + L + NK+ P + P+
Sbjct: 16 LNLSRNQLSLLPP--YICQLPLRVLIVSNNKLGALPPDIGTLGSLRQLDVSSNELQSLPS 73
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEA-FWCNRIGLKEIPKEIGKLTQLDTFGA 508
E+ L +L +LN+ N L+ L E+GDL + F CNR+ IP +L L
Sbjct: 74 ELCGLSSLRDLNVRRNQLSTLPEELGDLPLVRLDFSCNRV--SRIPVSFCRLRHLQVILL 131
Query: 509 RGNELKTIPEEMTSLAKL---RWLTLENNQ 589
N L++ P ++ KL ++L+ E Q
Sbjct: 132 DSNPLQSPPAQVCLKGKLHIFKYLSTEAGQ 161
>AF053356-12|AAC78793.1| 832|Homo sapiens leucin rich neuronal
protein protein.
Length = 832
Score = 79.4 bits (187), Expect = 1e-14
Identities = 48/139 (34%), Positives = 73/139 (52%)
Frame = +2
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
+GNL L LNLS N L++L P I L L + L +P +IG L L
Sbjct: 110 LGNLTALTYLNLSRNQLSLLPPYICQLP-LRVLIVSNNKLGALPPDIGTLGSLRQLDVSS 168
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
NEL+++P E+ L+ LR L + NQ+ TLP+ + + LV + NR+ + P S + +
Sbjct: 169 NELQSLPSELCGLSSLRDLNVRRNQLSTLPEELGDL-PLVRLDFSCNRVSRIPVSFCRLR 227
Query: 695 ELMFLQLNSNQISSVPANL 751
L + L+SN + S PA +
Sbjct: 228 HLQVILLDSNPLQSPPAQV 246
Score = 46.4 bits (105), Expect = 1e-04
Identities = 31/115 (26%), Positives = 56/115 (48%)
Frame = +2
Query: 470 EIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLR 649
++ +TQ D N +PE L L L+L +N + L + +TAL + NL
Sbjct: 66 DLSDITQADL---SRNRFPEVPEAACQLVSLEGLSLYHNCLRCLNPALGNLTALTYLNLS 122
Query: 650 NNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
N+L P I + L L +++N++ ++P ++ T + L +D+ SN + L
Sbjct: 123 RNQLSLLPPYICQL-PLRVLIVSNNKLGALPPDIGT--LGSLRQLDVSSNELQSL 174
Score = 45.2 bits (102), Expect = 3e-04
Identities = 39/150 (26%), Positives = 66/150 (44%), Gaps = 5/150 (3%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTC-LEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
L+L+ +++ +P Y C L + L + NK+ P + P+
Sbjct: 119 LNLSRNQLSLLPP--YICQLPLRVLIVSNNKLGALPPDIGTLGSLRQLDVSSNELQSLPS 176
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEA-FWCNRIGLKEIPKEIGKLTQLDTFGA 508
E+ L +L +LN+ N L+ L E+GDL + F CNR+ IP +L L
Sbjct: 177 ELCGLSSLRDLNVRRNQLSTLPEELGDLPLVRLDFSCNRV--SRIPVSFCRLRHLQVILL 234
Query: 509 RGNELKTIPEEMTSLAKL---RWLTLENNQ 589
N L++ P ++ KL ++L+ E Q
Sbjct: 235 DSNPLQSPPAQVCLKGKLHIFKYLSTEAGQ 264
>BC047306-1|AAH47306.1| 367|Homo sapiens leucine rich repeat
containing 28 protein.
Length = 367
Score = 78.6 bits (185), Expect = 3e-14
Identities = 52/200 (26%), Positives = 95/200 (47%), Gaps = 2/200 (1%)
Frame = +2
Query: 173 EITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXX-XXXXXXXXXXXXXXXPTEIGNLK 349
E+ + GL Y +E LY+ +N ++ P P IG+L
Sbjct: 33 ELLKDEGLQY----LERLYMKRNSLTSLPENLAQKLPNLVELYLHSNNIVVVPEAIGSLV 88
Query: 350 NLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKT 529
L L+LS N L ++ PEIG L L L+ +P E+G L +L T N L T
Sbjct: 89 KLQCLDLSDNALEIVCPEIGRLRALRHLRLANNQLQFLPPEVGDLKELQTLDISTNRLLT 148
Query: 530 IPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFL 709
+PE + L++LT++ N++ +P + ++ +L ++ NRL P + + +EL ++
Sbjct: 149 LPERLHMCLSLQYLTVDRNRLWYVPRHLCQLPSLNELSMAGNRLAFLPLDLGRSRELQYV 208
Query: 710 QLNSN-QISSVPANLDTSLV 766
+++N + +P+ L ++
Sbjct: 209 YVDNNIHLKGLPSYLYNKVI 228
>AY358082-1|AAQ88449.1| 312|Homo sapiens ASEL436 protein.
Length = 312
Score = 78.6 bits (185), Expect = 3e-14
Identities = 52/200 (26%), Positives = 95/200 (47%), Gaps = 2/200 (1%)
Frame = +2
Query: 173 EITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXX-XXXXXXXXXXXXXXXPTEIGNLK 349
E+ + GL Y +E LY+ +N ++ P P IG+L
Sbjct: 33 ELLKDEGLQY----LERLYMKRNSLTSLPENLAQKLPNLVELYLHSNNIVVVPEAIGSLV 88
Query: 350 NLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKT 529
L L+LS N L ++ PEIG L L L+ +P E+G L +L T N L T
Sbjct: 89 KLQCLDLSDNALEIVCPEIGRLRALRHLRLANNQLQFLPPEVGDLKELQTLDISTNRLLT 148
Query: 530 IPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFL 709
+PE + L++LT++ N++ +P + ++ +L ++ NRL P + + +EL ++
Sbjct: 149 LPERLHMCLSLQYLTVDRNRLWYVPRHLCQLPSLNELSMAGNRLAFLPLDLGRSRELQYV 208
Query: 710 QLNSN-QISSVPANLDTSLV 766
+++N + +P+ L ++
Sbjct: 209 YVDNNIHLKGLPSYLYNKVI 228
>BC106893-1|AAI06894.1| 250|Homo sapiens LRRC10 protein protein.
Length = 250
Score = 76.2 bits (179), Expect = 1e-13
Identities = 49/160 (30%), Positives = 81/160 (50%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P + + + LV L LS N LN L PE+G L+ L+ + K +P+ + L QL
Sbjct: 18 PLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALPQVVCTLKQLCILY 77
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
N+L +P E++ L LR L +E N + LPD + ++ L + +N L P +
Sbjct: 78 LGNNKLCDLPSELSLLQNLRTLWIEANCLTQLPDVVCELSLLKTLHAGSNALRLLPGQLR 137
Query: 686 KCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
+ +EL + L+ N+++ P L +P L +ID+ N I
Sbjct: 138 RLQELRTIWLSGNRLTDFPTVL--LHMPFLEVIDVDWNSI 175
Score = 61.7 bits (143), Expect = 3e-09
Identities = 40/140 (28%), Positives = 65/140 (46%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P E+G L+NL L L +N L + L++L + L ++P E+ L L T
Sbjct: 41 PPELGQLQNLQILALDFNNFKALPQVVCTLKQLCILYLGNNKLCDLPSELSLLQNLRTLW 100
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
N L +P+ + L+ L+ L +N + LP + R+ L L NRL FP+ +L
Sbjct: 101 IEANCLTQLPDVVCELSLLKTLHAGSNALRLLPGQLRRLQELRTIWLSGNRLTDFPTVLL 160
Query: 686 KCKELMFLQLNSNQISSVPA 745
L + ++ N I P+
Sbjct: 161 HMPFLEVIDVDWNSIRYFPS 180
>BC106892-1|AAI06893.1| 249|Homo sapiens LRRC10 protein protein.
Length = 249
Score = 76.2 bits (179), Expect = 1e-13
Identities = 49/160 (30%), Positives = 81/160 (50%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P + + + LV L LS N LN L PE+G L+ L+ + K +P+ + L QL
Sbjct: 17 PLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALPQVVCTLKQLCILY 76
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
N+L +P E++ L LR L +E N + LPD + ++ L + +N L P +
Sbjct: 77 LGNNKLCDLPSELSLLQNLRTLWIEANCLTQLPDVVCELSLLKTLHAGSNALRLLPGQLR 136
Query: 686 KCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
+ +EL + L+ N+++ P L +P L +ID+ N I
Sbjct: 137 RLQELRTIWLSGNRLTDFPTVL--LHMPFLEVIDVDWNSI 174
Score = 61.7 bits (143), Expect = 3e-09
Identities = 40/140 (28%), Positives = 65/140 (46%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P E+G L+NL L L +N L + L++L + L ++P E+ L L T
Sbjct: 40 PPELGQLQNLQILALDFNNFKALPQVVCTLKQLCILYLGNNKLCDLPSELSLLQNLRTLW 99
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
N L +P+ + L+ L+ L +N + LP + R+ L L NRL FP+ +L
Sbjct: 100 IEANCLTQLPDVVCELSLLKTLHAGSNALRLLPGQLRRLQELRTIWLSGNRLTDFPTVLL 159
Query: 686 KCKELMFLQLNSNQISSVPA 745
L + ++ N I P+
Sbjct: 160 HMPFLEVIDVDWNSIRYFPS 179
>BC090881-1|AAH90881.1| 277|Homo sapiens leucine rich repeat
containing 10 protein.
Length = 277
Score = 76.2 bits (179), Expect = 1e-13
Identities = 49/160 (30%), Positives = 81/160 (50%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P + + + LV L LS N LN L PE+G L+ L+ + K +P+ + L QL
Sbjct: 45 PLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALPQVVCTLKQLCILY 104
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
N+L +P E++ L LR L +E N + LPD + ++ L + +N L P +
Sbjct: 105 LGNNKLCDLPSELSLLQNLRTLWIEANCLTQLPDVVCELSLLKTLHAGSNALRLLPGQLR 164
Query: 686 KCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
+ +EL + L+ N+++ P L +P L +ID+ N I
Sbjct: 165 RLQELRTIWLSGNRLTDFPTVL--LHMPFLEVIDVDWNSI 202
Score = 61.7 bits (143), Expect = 3e-09
Identities = 40/140 (28%), Positives = 65/140 (46%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P E+G L+NL L L +N L + L++L + L ++P E+ L L T
Sbjct: 68 PPELGQLQNLQILALDFNNFKALPQVVCTLKQLCILYLGNNKLCDLPSELSLLQNLRTLW 127
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
N L +P+ + L+ L+ L +N + LP + R+ L L NRL FP+ +L
Sbjct: 128 IEANCLTQLPDVVCELSLLKTLHAGSNALRLLPGQLRRLQELRTIWLSGNRLTDFPTVLL 187
Query: 686 KCKELMFLQLNSNQISSVPA 745
L + ++ N I P+
Sbjct: 188 HMPFLEVIDVDWNSIRYFPS 207
>AK123908-1|BAC85724.1| 250|Homo sapiens protein ( Homo sapiens
cDNA FLJ41914 fis, clone PERIC2001228. ).
Length = 250
Score = 76.2 bits (179), Expect = 1e-13
Identities = 49/160 (30%), Positives = 81/160 (50%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P + + + LV L LS N LN L PE+G L+ L+ + K +P+ + L QL
Sbjct: 18 PLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALPQVVCTLKQLCILY 77
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
N+L +P E++ L LR L +E N + LPD + ++ L + +N L P +
Sbjct: 78 LGNNKLCDLPSELSLLQNLRTLWIEANCLTQLPDVVCELSLLKTLHAGSNALRLLPGQLR 137
Query: 686 KCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
+ +EL + L+ N+++ P L +P L +ID+ N I
Sbjct: 138 RLQELRTIWLSGNRLTDFPTVL--LHMPFLEVIDVDWNSI 175
Score = 61.7 bits (143), Expect = 3e-09
Identities = 40/140 (28%), Positives = 65/140 (46%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P E+G L+NL L L +N L + L++L + L ++P E+ L L T
Sbjct: 41 PPELGQLQNLQILALDFNNFKALPQVVCTLKQLCILYLGNNKLCDLPSELSLLQNLRTLW 100
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
N L +P+ + L+ L+ L +N + LP + R+ L L NRL FP+ +L
Sbjct: 101 IEANCLTQLPDVVCELSLLKTLHAGSNALRLLPGQLRRLQELRTIWLSGNRLTDFPTVLL 160
Query: 686 KCKELMFLQLNSNQISSVPA 745
L + ++ N I P+
Sbjct: 161 HMPFLEVIDVDWNSIRYFPS 180
>AB016816-1|BAA74737.1| 1052|Homo sapiens MASL1 protein.
Length = 1052
Score = 76.2 bits (179), Expect = 1e-13
Identities = 49/178 (27%), Positives = 78/178 (43%)
Frame = +2
Query: 212 EVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNV 391
E+ L L N++ P + P + L L L++ +N L
Sbjct: 136 ELRKLNLSHNQLPALPAQLGALAHLEELDVSFNRLAHLPDSLSCLSRLRTLDVDHNQLTA 195
Query: 392 LIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWL 571
++ L LE + L+ +P++I L L G EL T+P LA L L
Sbjct: 196 FPRQLLQLVALEELDVSSNRLRGLPEDISALRALKILWLSGAELGTLPAGFCELASLESL 255
Query: 572 TLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPA 745
L+NN ++ LP + L NL +N E+FP+++L L L L+ NQ++SVP+
Sbjct: 256 MLDNNGLQALPAQFSCLQRLKMLNLSSNLFEEFPAALLPLAGLEELYLSRNQLTSVPS 313
Score = 67.3 bits (157), Expect = 6e-11
Identities = 40/142 (28%), Positives = 69/142 (48%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P ++G L +L L++S+N L L + L +L + L P+++ +L L+
Sbjct: 151 PAQLGALAHLEELDVSFNRLAHLPDSLSCLSRLRTLDVDHNQLTAFPRQLLQLVALEELD 210
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
N L+ +PE++++L L+ L L ++ TLP + +L L NN L+ P+
Sbjct: 211 VSSNRLRGLPEDISALRALKILWLSGAELGTLPAGFCELASLESLMLDNNGLQALPAQFS 270
Query: 686 KCKELMFLQLNSNQISSVPANL 751
+ L L L+SN PA L
Sbjct: 271 CLQRLKMLNLSSNLFEEFPAAL 292
Score = 66.9 bits (156), Expect = 8e-11
Identities = 44/155 (28%), Positives = 74/155 (47%)
Frame = +2
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
+ L+ L LNLS+N L L ++G L LE + L +P + L++L T
Sbjct: 131 VSALRELRKLNLSHNQLPALPAQLGALAHLEELDVSFNRLAHLPDSLSCLSRLRTLDVDH 190
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N+L P ++ L L L + +N++ LP+ + + AL L L P+ +
Sbjct: 191 NQLTAFPRQLLQLVALEELDVSSNRLRGLPEDISALRALKILWLSGAELGTLPAGFCELA 250
Query: 695 ELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSN 799
L L L++N + ++PA S + L M++L SN
Sbjct: 251 SLESLMLDNNGLQALPAQF--SCLQRLKMLNLSSN 283
Score = 66.9 bits (156), Expect = 8e-11
Identities = 53/212 (25%), Positives = 87/212 (41%)
Frame = +2
Query: 176 ITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 355
+ +P L + L + N+++ FP + P +I L+ L
Sbjct: 170 LAHLPDSLSCLSRLRTLDVDHNQLTAFPRQLLQLVALEELDVSSNRLRGLPEDISALRAL 229
Query: 356 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 535
L LS L L +L LE+ + GL+ +P + L +L N + P
Sbjct: 230 KILWLSGAELGTLPAGFCELASLESLMLDNNGLQALPAQFSCLQRLKMLNLSSNLFEEFP 289
Query: 536 EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQL 715
+ LA L L L NQ+ ++P + + L+ L NNR+ P SI++ L L L
Sbjct: 290 AALLPLAGLEELYLSRNQLTSVPSLISGLGRLLTLWLDNNRIRYLPDSIVELTGLEELVL 349
Query: 716 NSNQISSVPANLDTSLVPGLXMIDLRSNPICE 811
NQI+ +P + GL I + NP+ +
Sbjct: 350 QGNQIAVLPDHFGQLSRVGLWKI--KDNPLIQ 379
Score = 60.1 bits (139), Expect = 1e-08
Identities = 43/205 (20%), Positives = 84/205 (40%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L ++ ++T P L + +E L + N++ P + P
Sbjct: 186 LDVDHNQLTAFPRQLLQLVALEELDVSSNRLRGLPEDISALRALKILWLSGAELGTLPAG 245
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
L +L +L L N L L + L++L+ + +E P + L L+
Sbjct: 246 FCELASLESLMLDNNGLQALPAQFSCLQRLKMLNLSSNLFEEFPAALLPLAGLEELYLSR 305
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N+L ++P ++ L +L L L+NN+I LPD++ +T L L+ N++ P +
Sbjct: 306 NQLTSVPSLISGLGRLLTLWLDNNRIRYLPDSIVELTGLEELVLQGNQIAVLPDHFGQLS 365
Query: 695 ELMFLQLNSNQISSVPANLDTSLVP 769
+ ++ N + P + +P
Sbjct: 366 RVGLWKIKDNPLIQPPYEVCMKGIP 390
Score = 51.6 bits (118), Expect = 3e-06
Identities = 45/156 (28%), Positives = 69/156 (44%), Gaps = 3/156 (1%)
Frame = +2
Query: 341 NLKNLVNLNLSYNPLNVLIPEIGD-LEKLEAFWCNRIGLKEIPKEIGKLTQ-LDTFGARG 514
NL ++ LNL N L + +G L L R +P + +L L
Sbjct: 61 NLGDIEALNLGNNGLEEVPEGLGSALGSLRVLVLRRNRFARLPPAVAELGHHLTELDVSH 120
Query: 515 NELKTIPEEMTS-LAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 691
N L + E+ S L +LR L L +NQ+ LP + + L ++ NRL P S+
Sbjct: 121 NRLTALGAEVVSALRELRKLNLSHNQLPALPAQLGALAHLEELDVSFNRLAHLPDSLSCL 180
Query: 692 KELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSN 799
L L ++ NQ+++ P L LV L +D+ SN
Sbjct: 181 SRLRTLDVDHNQLTAFPRQL-LQLV-ALEELDVSSN 214
>AK001637-1|BAA91801.1| 183|Homo sapiens protein ( Homo sapiens
cDNA FLJ10775 fis, clone NT2RP4000312, weakly similar to
ADENYLATE CYCLASE (EC 4.6.1.1). ).
Length = 183
Score = 74.9 bits (176), Expect = 3e-13
Identities = 44/142 (30%), Positives = 69/142 (48%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P I K L + S NPL L +L+ L N I L+ +P+ IG L L +
Sbjct: 17 PESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLASLE 76
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
R N L +P+ +T L +L L L NN+I LP+++ + L L N+L + P I
Sbjct: 77 LRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIG 136
Query: 686 KCKELMFLQLNSNQISSVPANL 751
K L+ L ++ N++ +P +
Sbjct: 137 NLKNLLCLDVSENRLERLPEEI 158
Score = 73.3 bits (172), Expect = 1e-12
Identities = 47/176 (26%), Positives = 74/176 (42%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L ++ EI EIP + C ++ N ++ P P
Sbjct: 6 LDVSRNEIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPEN 65
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
IGNL NL +L L N L L + L +LE + +P+ IG L L G
Sbjct: 66 IGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDG 125
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 682
N+L +P+E+ +L L L + N++E LP+ + +T+L + N LE P +
Sbjct: 126 NQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGL 181
Score = 65.3 bits (152), Expect = 3e-10
Identities = 43/182 (23%), Positives = 79/182 (43%)
Frame = +2
Query: 209 LEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLN 388
+++ L + +N+I P P L+NL L+++ L
Sbjct: 1 MQLVELDVSRNEIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQ 60
Query: 389 VLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRW 568
L IG+L L + L +P + +L +L+ NE+ +PE + +L L+
Sbjct: 61 SLPENIGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKD 120
Query: 569 LTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPAN 748
L L+ NQ+ LP + + L+ ++ NRLE+ P I L L ++ N + ++P
Sbjct: 121 LWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDG 180
Query: 749 LD 754
L+
Sbjct: 181 LE 182
Score = 54.8 bits (126), Expect = 4e-07
Identities = 30/108 (27%), Positives = 52/108 (48%)
Frame = +2
Query: 440 NRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDR 619
+R + EIP+ I L GN L +PE L L L++ + +++LP+ +
Sbjct: 9 SRNEIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGN 68
Query: 620 MTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSL 763
+ L LR N L P S+ + + L L L +N+I ++P ++ L
Sbjct: 69 LYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALL 116
>BC051322-1|AAH51322.1| 810|Homo sapiens leucine rich repeat
containing 8 family, member A protein.
Length = 810
Score = 74.5 bits (175), Expect = 4e-13
Identities = 41/122 (33%), Positives = 61/122 (50%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P +IGNL NL L L+ N + + ++ KL + L +P +IG L L
Sbjct: 655 PIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLA 714
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
N ++T+P E+ KLR L L NN +++LP + +T L LR NRLE P +
Sbjct: 715 ITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELG 774
Query: 686 KC 691
+C
Sbjct: 775 EC 776
Score = 72.1 bits (169), Expect = 2e-12
Identities = 45/145 (31%), Positives = 65/145 (44%), Gaps = 2/145 (1%)
Frame = +2
Query: 176 ITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 355
I IP + +E LYL++NKI P + P +IG L+NL
Sbjct: 651 IAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNL 710
Query: 356 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 535
NL ++ N + L PE+ KL A L+ +P +G+LT L RGN L+ +P
Sbjct: 711 QNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLP 770
Query: 536 EEM--TSLAKLRWLTLENNQIETLP 604
E+ L K L +E + TLP
Sbjct: 771 VELGECPLLKRSGLVVEEDLFNTLP 795
Score = 66.1 bits (154), Expect = 1e-10
Identities = 40/137 (29%), Positives = 69/137 (50%)
Frame = +2
Query: 341 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 520
+L L L L YN + + +IG+L LE + NR +++IP ++ +L N
Sbjct: 637 HLHRLTCLKLWYNHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNN 696
Query: 521 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 700
L +P ++ L L+ L + N+IETLP + + L +L NN L+ PS + + L
Sbjct: 697 LTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNL 756
Query: 701 MFLQLNSNQISSVPANL 751
++L N++ +P L
Sbjct: 757 TQIELRGNRLECLPVEL 773
Score = 44.8 bits (101), Expect = 4e-04
Identities = 34/133 (25%), Positives = 54/133 (40%), Gaps = 2/133 (1%)
Frame = +2
Query: 152 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
RL LN +I +IP L+ C ++ +L L N ++ P + P
Sbjct: 666 RLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETLPP 725
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
E+ + L L+L N L L +G+L L L+ +P E+G+ L G
Sbjct: 726 ELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELGECPLLKRSGLV 785
Query: 512 GNE--LKTIPEEM 544
E T+P E+
Sbjct: 786 VEEDLFNTLPPEV 798
>AY358286-1|AAQ88653.1| 546|Homo sapiens RQTI221 protein.
Length = 546
Score = 74.5 bits (175), Expect = 4e-13
Identities = 41/122 (33%), Positives = 61/122 (50%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P +IGNL NL L L+ N + + ++ KL + L +P +IG L L
Sbjct: 391 PIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLA 450
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
N ++T+P E+ KLR L L NN +++LP + +T L LR NRLE P +
Sbjct: 451 ITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELG 510
Query: 686 KC 691
+C
Sbjct: 511 EC 512
Score = 72.1 bits (169), Expect = 2e-12
Identities = 45/145 (31%), Positives = 65/145 (44%), Gaps = 2/145 (1%)
Frame = +2
Query: 176 ITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 355
I IP + +E LYL++NKI P + P +IG L+NL
Sbjct: 387 IAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNL 446
Query: 356 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 535
NL ++ N + L PE+ KL A L+ +P +G+LT L RGN L+ +P
Sbjct: 447 QNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLP 506
Query: 536 EEM--TSLAKLRWLTLENNQIETLP 604
E+ L K L +E + TLP
Sbjct: 507 VELGECPLLKRSGLVVEEDLFNTLP 531
Score = 66.1 bits (154), Expect = 1e-10
Identities = 40/137 (29%), Positives = 69/137 (50%)
Frame = +2
Query: 341 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 520
+L L L L YN + + +IG+L LE + NR +++IP ++ +L N
Sbjct: 373 HLHRLTCLKLWYNHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNN 432
Query: 521 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 700
L +P ++ L L+ L + N+IETLP + + L +L NN L+ PS + + L
Sbjct: 433 LTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNL 492
Query: 701 MFLQLNSNQISSVPANL 751
++L N++ +P L
Sbjct: 493 TQIELRGNRLECLPVEL 509
Score = 44.8 bits (101), Expect = 4e-04
Identities = 34/133 (25%), Positives = 54/133 (40%), Gaps = 2/133 (1%)
Frame = +2
Query: 152 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
RL LN +I +IP L+ C ++ +L L N ++ P + P
Sbjct: 402 RLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETLPP 461
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
E+ + L L+L N L L +G+L L L+ +P E+G+ L G
Sbjct: 462 ELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELGECPLLKRSGLV 521
Query: 512 GNE--LKTIPEEM 544
E T+P E+
Sbjct: 522 VEEDLFNTLPPEV 534
>AY143166-1|AAN18279.1| 810|Homo sapiens leucine-rich
repeat-containing 8 protein.
Length = 810
Score = 74.5 bits (175), Expect = 4e-13
Identities = 41/122 (33%), Positives = 61/122 (50%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P +IGNL NL L L+ N + + ++ KL + L +P +IG L L
Sbjct: 655 PIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLA 714
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
N ++T+P E+ KLR L L NN +++LP + +T L LR NRLE P +
Sbjct: 715 ITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELG 774
Query: 686 KC 691
+C
Sbjct: 775 EC 776
Score = 72.1 bits (169), Expect = 2e-12
Identities = 45/145 (31%), Positives = 65/145 (44%), Gaps = 2/145 (1%)
Frame = +2
Query: 176 ITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 355
I IP + +E LYL++NKI P + P +IG L+NL
Sbjct: 651 IAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNL 710
Query: 356 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 535
NL ++ N + L PE+ KL A L+ +P +G+LT L RGN L+ +P
Sbjct: 711 QNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLP 770
Query: 536 EEM--TSLAKLRWLTLENNQIETLP 604
E+ L K L +E + TLP
Sbjct: 771 VELGECPLLKRSGLVVEEDLFNTLP 795
Score = 66.1 bits (154), Expect = 1e-10
Identities = 40/137 (29%), Positives = 69/137 (50%)
Frame = +2
Query: 341 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 520
+L L L L YN + + +IG+L LE + NR +++IP ++ +L N
Sbjct: 637 HLHRLTCLKLWYNHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNN 696
Query: 521 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 700
L +P ++ L L+ L + N+IETLP + + L +L NN L+ PS + + L
Sbjct: 697 LTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNL 756
Query: 701 MFLQLNSNQISSVPANL 751
++L N++ +P L
Sbjct: 757 TQIELRGNRLECLPVEL 773
Score = 44.8 bits (101), Expect = 4e-04
Identities = 34/133 (25%), Positives = 54/133 (40%), Gaps = 2/133 (1%)
Frame = +2
Query: 152 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
RL LN +I +IP L+ C ++ +L L N ++ P + P
Sbjct: 666 RLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETLPP 725
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
E+ + L L+L N L L +G+L L L+ +P E+G+ L G
Sbjct: 726 ELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELGECPLLKRSGLV 785
Query: 512 GNE--LKTIPEEM 544
E T+P E+
Sbjct: 786 VEEDLFNTLPPEV 798
>AL672142-1|CAI10839.1| 810|Homo sapiens leucine rich repeat
containing 8 family, member A protein.
Length = 810
Score = 74.5 bits (175), Expect = 4e-13
Identities = 41/122 (33%), Positives = 61/122 (50%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P +IGNL NL L L+ N + + ++ KL + L +P +IG L L
Sbjct: 655 PIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLA 714
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
N ++T+P E+ KLR L L NN +++LP + +T L LR NRLE P +
Sbjct: 715 ITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELG 774
Query: 686 KC 691
+C
Sbjct: 775 EC 776
Score = 72.1 bits (169), Expect = 2e-12
Identities = 45/145 (31%), Positives = 65/145 (44%), Gaps = 2/145 (1%)
Frame = +2
Query: 176 ITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 355
I IP + +E LYL++NKI P + P +IG L+NL
Sbjct: 651 IAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNL 710
Query: 356 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 535
NL ++ N + L PE+ KL A L+ +P +G+LT L RGN L+ +P
Sbjct: 711 QNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLP 770
Query: 536 EEM--TSLAKLRWLTLENNQIETLP 604
E+ L K L +E + TLP
Sbjct: 771 VELGECPLLKRSGLVVEEDLFNTLP 795
Score = 66.1 bits (154), Expect = 1e-10
Identities = 40/137 (29%), Positives = 69/137 (50%)
Frame = +2
Query: 341 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 520
+L L L L YN + + +IG+L LE + NR +++IP ++ +L N
Sbjct: 637 HLHRLTCLKLWYNHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNN 696
Query: 521 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 700
L +P ++ L L+ L + N+IETLP + + L +L NN L+ PS + + L
Sbjct: 697 LTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNL 756
Query: 701 MFLQLNSNQISSVPANL 751
++L N++ +P L
Sbjct: 757 TQIELRGNRLECLPVEL 773
Score = 44.8 bits (101), Expect = 4e-04
Identities = 34/133 (25%), Positives = 54/133 (40%), Gaps = 2/133 (1%)
Frame = +2
Query: 152 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
RL LN +I +IP L+ C ++ +L L N ++ P + P
Sbjct: 666 RLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETLPP 725
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
E+ + L L+L N L L +G+L L L+ +P E+G+ L G
Sbjct: 726 ELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELGECPLLKRSGLV 785
Query: 512 GNE--LKTIPEEM 544
E T+P E+
Sbjct: 786 VEEDLFNTLPPEV 798
>AK027495-1|BAB55153.1| 474|Homo sapiens protein ( Homo sapiens
cDNA FLJ14589 fis, clone NT2RM4001876, weakly similar to
RAS SUPPRESSOR PROTEIN 1. ).
Length = 474
Score = 74.5 bits (175), Expect = 4e-13
Identities = 41/122 (33%), Positives = 61/122 (50%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P +IGNL NL L L+ N + + ++ KL + L +P +IG L L
Sbjct: 319 PIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLA 378
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
N ++T+P E+ KLR L L NN +++LP + +T L LR NRLE P +
Sbjct: 379 ITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELG 438
Query: 686 KC 691
+C
Sbjct: 439 EC 440
Score = 72.1 bits (169), Expect = 2e-12
Identities = 45/145 (31%), Positives = 65/145 (44%), Gaps = 2/145 (1%)
Frame = +2
Query: 176 ITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 355
I IP + +E LYL++NKI P + P +IG L+NL
Sbjct: 315 IAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNL 374
Query: 356 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 535
NL ++ N + L PE+ KL A L+ +P +G+LT L RGN L+ +P
Sbjct: 375 QNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLP 434
Query: 536 EEM--TSLAKLRWLTLENNQIETLP 604
E+ L K L +E + TLP
Sbjct: 435 VELGECPLLKRSGLVVEEDLFNTLP 459
Score = 66.1 bits (154), Expect = 1e-10
Identities = 40/137 (29%), Positives = 69/137 (50%)
Frame = +2
Query: 341 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 520
+L L L L YN + + +IG+L LE + NR +++IP ++ +L N
Sbjct: 301 HLHRLTCLKLWYNHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNN 360
Query: 521 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 700
L +P ++ L L+ L + N+IETLP + + L +L NN L+ PS + + L
Sbjct: 361 LTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNL 420
Query: 701 MFLQLNSNQISSVPANL 751
++L N++ +P L
Sbjct: 421 TQIELRGNRLECLPVEL 437
Score = 44.8 bits (101), Expect = 4e-04
Identities = 34/133 (25%), Positives = 54/133 (40%), Gaps = 2/133 (1%)
Frame = +2
Query: 152 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
RL LN +I +IP L+ C ++ +L L N ++ P + P
Sbjct: 330 RLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETLPP 389
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
E+ + L L+L N L L +G+L L L+ +P E+G+ L G
Sbjct: 390 ELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELGECPLLKRSGLV 449
Query: 512 GNE--LKTIPEEM 544
E T+P E+
Sbjct: 450 VEEDLFNTLPPEV 462
>AK001199-1|BAA91549.1| 221|Homo sapiens protein ( Homo sapiens
cDNA FLJ10337 fis, clone NT2RM2000714, weakly similar to
RAS SUPPRESSOR PROTEIN 1. ).
Length = 221
Score = 74.5 bits (175), Expect = 4e-13
Identities = 41/122 (33%), Positives = 61/122 (50%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P +IGNL NL L L+ N + + ++ KL + L +P +IG L L
Sbjct: 66 PIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLA 125
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
N ++T+P E+ KLR L L NN +++LP + +T L LR NRLE P +
Sbjct: 126 ITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELG 185
Query: 686 KC 691
+C
Sbjct: 186 EC 187
Score = 72.1 bits (169), Expect = 2e-12
Identities = 45/145 (31%), Positives = 65/145 (44%), Gaps = 2/145 (1%)
Frame = +2
Query: 176 ITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 355
I IP + +E LYL++NKI P + P +IG L+NL
Sbjct: 62 IAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNL 121
Query: 356 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 535
NL ++ N + L PE+ KL A L+ +P +G+LT L RGN L+ +P
Sbjct: 122 QNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLP 181
Query: 536 EEM--TSLAKLRWLTLENNQIETLP 604
E+ L K L +E + TLP
Sbjct: 182 VELGECPLLKRSGLVVEEDLFNTLP 206
Score = 66.1 bits (154), Expect = 1e-10
Identities = 40/137 (29%), Positives = 69/137 (50%)
Frame = +2
Query: 341 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 520
+L L L L YN + + +IG+L LE + NR +++IP ++ +L N
Sbjct: 48 HLHRLTCLKLWYNHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNN 107
Query: 521 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 700
L +P ++ L L+ L + N+IETLP + + L +L NN L+ PS + + L
Sbjct: 108 LTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNL 167
Query: 701 MFLQLNSNQISSVPANL 751
++L N++ +P L
Sbjct: 168 TQIELRGNRLECLPVEL 184
Score = 44.8 bits (101), Expect = 4e-04
Identities = 34/133 (25%), Positives = 54/133 (40%), Gaps = 2/133 (1%)
Frame = +2
Query: 152 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
RL LN +I +IP L+ C ++ +L L N ++ P + P
Sbjct: 77 RLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETLPP 136
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
E+ + L L+L N L L +G+L L L+ +P E+G+ L G
Sbjct: 137 ELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELGECPLLKRSGLV 196
Query: 512 GNE--LKTIPEEM 544
E T+P E+
Sbjct: 197 VEEDLFNTLPPEV 209
>AB037858-1|BAA92675.1| 811|Homo sapiens KIAA1437 protein protein.
Length = 811
Score = 74.5 bits (175), Expect = 4e-13
Identities = 41/122 (33%), Positives = 61/122 (50%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P +IGNL NL L L+ N + + ++ KL + L +P +IG L L
Sbjct: 656 PIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLA 715
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
N ++T+P E+ KLR L L NN +++LP + +T L LR NRLE P +
Sbjct: 716 ITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELG 775
Query: 686 KC 691
+C
Sbjct: 776 EC 777
Score = 72.1 bits (169), Expect = 2e-12
Identities = 45/145 (31%), Positives = 65/145 (44%), Gaps = 2/145 (1%)
Frame = +2
Query: 176 ITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 355
I IP + +E LYL++NKI P + P +IG L+NL
Sbjct: 652 IAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNL 711
Query: 356 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 535
NL ++ N + L PE+ KL A L+ +P +G+LT L RGN L+ +P
Sbjct: 712 QNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLP 771
Query: 536 EEM--TSLAKLRWLTLENNQIETLP 604
E+ L K L +E + TLP
Sbjct: 772 VELGECPLLKRSGLVVEEDLFNTLP 796
Score = 66.1 bits (154), Expect = 1e-10
Identities = 40/137 (29%), Positives = 69/137 (50%)
Frame = +2
Query: 341 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 520
+L L L L YN + + +IG+L LE + NR +++IP ++ +L N
Sbjct: 638 HLHRLTCLKLWYNHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNN 697
Query: 521 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 700
L +P ++ L L+ L + N+IETLP + + L +L NN L+ PS + + L
Sbjct: 698 LTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNL 757
Query: 701 MFLQLNSNQISSVPANL 751
++L N++ +P L
Sbjct: 758 TQIELRGNRLECLPVEL 774
Score = 44.8 bits (101), Expect = 4e-04
Identities = 34/133 (25%), Positives = 54/133 (40%), Gaps = 2/133 (1%)
Frame = +2
Query: 152 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
RL LN +I +IP L+ C ++ +L L N ++ P + P
Sbjct: 667 RLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETLPP 726
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
E+ + L L+L N L L +G+L L L+ +P E+G+ L G
Sbjct: 727 ELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELGECPLLKRSGLV 786
Query: 512 GNE--LKTIPEEM 544
E T+P E+
Sbjct: 787 VEEDLFNTLPPEV 799
>AK074723-1|BAC11161.1| 546|Homo sapiens protein ( Homo sapiens
cDNA FLJ90242 fis, clone NT2RM2001626, highly similar to
Leucine-rich repeat-containing protein 8 precursor. ).
Length = 546
Score = 73.7 bits (173), Expect = 7e-13
Identities = 41/122 (33%), Positives = 60/122 (49%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P +IGNL NL L L+ N + + ++ KL + L +P +IG L L
Sbjct: 391 PIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLA 450
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
N ++T+P E+ KLR L L NN + +LP + +T L LR NRLE P +
Sbjct: 451 ITANRIETLPPELFQCRKLRALHLGNNVLRSLPSRVGELTNLTQIELRGNRLECLPVELG 510
Query: 686 KC 691
+C
Sbjct: 511 EC 512
Score = 72.5 bits (170), Expect = 2e-12
Identities = 45/145 (31%), Positives = 65/145 (44%), Gaps = 2/145 (1%)
Frame = +2
Query: 176 ITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 355
I IP + +E LYL++NKI P + P +IG L+NL
Sbjct: 387 IAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNL 446
Query: 356 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 535
NL ++ N + L PE+ KL A L+ +P +G+LT L RGN L+ +P
Sbjct: 447 QNLAITANRIETLPPELFQCRKLRALHLGNNVLRSLPSRVGELTNLTQIELRGNRLECLP 506
Query: 536 EEM--TSLAKLRWLTLENNQIETLP 604
E+ L K L +E + TLP
Sbjct: 507 VELGECPLLKRSGLVVEEDLFNTLP 531
Score = 65.3 bits (152), Expect = 3e-10
Identities = 40/137 (29%), Positives = 68/137 (49%)
Frame = +2
Query: 341 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 520
+L L L L YN + + +IG+L LE + NR +++IP ++ +L N
Sbjct: 373 HLHRLTCLKLWYNHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNN 432
Query: 521 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 700
L +P ++ L L+ L + N+IETLP + + L +L NN L PS + + L
Sbjct: 433 LTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLRSLPSRVGELTNL 492
Query: 701 MFLQLNSNQISSVPANL 751
++L N++ +P L
Sbjct: 493 TQIELRGNRLECLPVEL 509
Score = 44.8 bits (101), Expect = 4e-04
Identities = 34/133 (25%), Positives = 54/133 (40%), Gaps = 2/133 (1%)
Frame = +2
Query: 152 RLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
RL LN +I +IP L+ C ++ +L L N ++ P + P
Sbjct: 402 RLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETLPP 461
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
E+ + L L+L N L L +G+L L L+ +P E+G+ L G
Sbjct: 462 ELFQCRKLRALHLGNNVLRSLPSRVGELTNLTQIELRGNRLECLPVELGECPLLKRSGLV 521
Query: 512 GNE--LKTIPEEM 544
E T+P E+
Sbjct: 522 VEEDLFNTLPPEV 534
>BC024159-1|AAH24159.2| 858|Homo sapiens leucine rich repeat
containing 8 family, member D protein.
Length = 858
Score = 72.5 bits (170), Expect = 2e-12
Identities = 48/186 (25%), Positives = 82/186 (44%), Gaps = 2/186 (1%)
Frame = +2
Query: 149 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFP--VEXXXXXXXXXXXXXXXXXXX 322
+ L L E+ IP +++ ++ L L N I +
Sbjct: 638 AELELQNCELERIPHAIFSLSNLQELDLKSNNIRTIEEIISFQHLKRLTCLKLWHNKIVT 697
Query: 323 XPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
P I ++KNL +L S N L L + L+KL + + IP EIG L L
Sbjct: 698 IPPSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQNLQHL 757
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 682
GN++ +P+++ KLR L L N I +LP+ + +++ L L+ N L++ P+ +
Sbjct: 758 HITGNKVDILPKQLFKCIKLRTLNLGQNCITSLPEKVGQLSQLTQLELKGNCLDRLPAQL 817
Query: 683 LKCKEL 700
+C+ L
Sbjct: 818 GQCRML 823
Score = 67.3 bits (157), Expect = 6e-11
Identities = 45/161 (27%), Positives = 79/161 (49%), Gaps = 3/161 (1%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIG---LKEIPKEIGKLTQLD 496
P I +L NL L+L N + I EI + L+ C ++ + IP I + L+
Sbjct: 651 PHAIFSLSNLQELDLKSNNIRT-IEEIISFQHLKRLTCLKLWHNKIVTIPPSITHVKNLE 709
Query: 497 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 676
+ N+L+++P + SL KLR L + N I +P + + L H ++ N+++ P
Sbjct: 710 SLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQNLQHLHITGNKVDILPK 769
Query: 677 SILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSN 799
+ KC +L L L N I+S+P + + L ++L+ N
Sbjct: 770 QLFKCIKLRTLNLGQNCITSLPEKV--GQLSQLTQLELKGN 808
>AY358874-1|AAQ89233.1| 501|Homo sapiens LRRC5 protein.
Length = 501
Score = 72.5 bits (170), Expect = 2e-12
Identities = 48/186 (25%), Positives = 82/186 (44%), Gaps = 2/186 (1%)
Frame = +2
Query: 149 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFP--VEXXXXXXXXXXXXXXXXXXX 322
+ L L E+ IP +++ ++ L L N I +
Sbjct: 281 AELELQNCELERIPHAIFSLSNLQELDLKSNNIRTIEEIISFQHLKRLTCLKLWHNKIVT 340
Query: 323 XPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
P I ++KNL +L S N L L + L+KL + + IP EIG L L
Sbjct: 341 IPPSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQNLQHL 400
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 682
GN++ +P+++ KLR L L N I +LP+ + +++ L L+ N L++ P+ +
Sbjct: 401 HITGNKVDILPKQLFKCIKLRTLNLGQNCITSLPEKVGQLSQLTQLELKGNCLDRLPAQL 460
Query: 683 LKCKEL 700
+C+ L
Sbjct: 461 GQCRML 466
Score = 67.3 bits (157), Expect = 6e-11
Identities = 45/161 (27%), Positives = 79/161 (49%), Gaps = 3/161 (1%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIG---LKEIPKEIGKLTQLD 496
P I +L NL L+L N + I EI + L+ C ++ + IP I + L+
Sbjct: 294 PHAIFSLSNLQELDLKSNNIRT-IEEIISFQHLKRLTCLKLWHNKIVTIPPSITHVKNLE 352
Query: 497 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 676
+ N+L+++P + SL KLR L + N I +P + + L H ++ N+++ P
Sbjct: 353 SLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQNLQHLHITGNKVDILPK 412
Query: 677 SILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSN 799
+ KC +L L L N I+S+P + + L ++L+ N
Sbjct: 413 QLFKCIKLRTLNLGQNCITSLPEKV--GQLSQLTQLELKGN 451
>AL391497-3|CAH72226.1| 858|Homo sapiens leucine rich repeat
containing 8 family, member D protein.
Length = 858
Score = 72.5 bits (170), Expect = 2e-12
Identities = 48/186 (25%), Positives = 82/186 (44%), Gaps = 2/186 (1%)
Frame = +2
Query: 149 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFP--VEXXXXXXXXXXXXXXXXXXX 322
+ L L E+ IP +++ ++ L L N I +
Sbjct: 638 AELELQNCELERIPHAIFSLSNLQELDLKSNNIRTIEEIISFQHLKRLTCLKLWHNKIVT 697
Query: 323 XPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
P I ++KNL +L S N L L + L+KL + + IP EIG L L
Sbjct: 698 IPPSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQNLQHL 757
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 682
GN++ +P+++ KLR L L N I +LP+ + +++ L L+ N L++ P+ +
Sbjct: 758 HITGNKVDILPKQLFKCIKLRTLNLGQNCITSLPEKVGQLSQLTQLELKGNCLDRLPAQL 817
Query: 683 LKCKEL 700
+C+ L
Sbjct: 818 GQCRML 823
Score = 67.3 bits (157), Expect = 6e-11
Identities = 45/161 (27%), Positives = 79/161 (49%), Gaps = 3/161 (1%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIG---LKEIPKEIGKLTQLD 496
P I +L NL L+L N + I EI + L+ C ++ + IP I + L+
Sbjct: 651 PHAIFSLSNLQELDLKSNNIRT-IEEIISFQHLKRLTCLKLWHNKIVTIPPSITHVKNLE 709
Query: 497 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 676
+ N+L+++P + SL KLR L + N I +P + + L H ++ N+++ P
Sbjct: 710 SLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQNLQHLHITGNKVDILPK 769
Query: 677 SILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSN 799
+ KC +L L L N I+S+P + + L ++L+ N
Sbjct: 770 QLFKCIKLRTLNLGQNCITSLPEKV--GQLSQLTQLELKGN 808
>AK222787-1|BAD96507.1| 671|Homo sapiens leucine rich repeat
containing 5 variant protein.
Length = 671
Score = 72.5 bits (170), Expect = 2e-12
Identities = 48/186 (25%), Positives = 82/186 (44%), Gaps = 2/186 (1%)
Frame = +2
Query: 149 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFP--VEXXXXXXXXXXXXXXXXXXX 322
+ L L E+ IP +++ ++ L L N I +
Sbjct: 451 AELELQNCELERIPHAIFSLSNLQELDLKSNNIRTIEEIISFQHLKRLTCLKLWHNKIVT 510
Query: 323 XPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
P I ++KNL +L S N L L + L+KL + + IP EIG L L
Sbjct: 511 IPPSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQDLQHL 570
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 682
GN++ +P+++ KLR L L N I +LP+ + +++ L L+ N L++ P+ +
Sbjct: 571 HITGNKVDILPKQLFKCIKLRTLNLGQNCITSLPEKVGQLSQLTQLELKGNCLDRLPAQL 630
Query: 683 LKCKEL 700
+C+ L
Sbjct: 631 GQCRML 636
Score = 67.3 bits (157), Expect = 6e-11
Identities = 45/161 (27%), Positives = 79/161 (49%), Gaps = 3/161 (1%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIG---LKEIPKEIGKLTQLD 496
P I +L NL L+L N + I EI + L+ C ++ + IP I + L+
Sbjct: 464 PHAIFSLSNLQELDLKSNNIRT-IEEIISFQHLKRLTCLKLWHNKIVTIPPSITHVKNLE 522
Query: 497 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 676
+ N+L+++P + SL KLR L + N I +P + + L H ++ N+++ P
Sbjct: 523 SLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQDLQHLHITGNKVDILPK 582
Query: 677 SILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSN 799
+ KC +L L L N I+S+P + + L ++L+ N
Sbjct: 583 QLFKCIKLRTLNLGQNCITSLPEKV--GQLSQLTQLELKGN 621
>AK001332-1|BAA91631.1| 682|Homo sapiens protein ( Homo sapiens cDNA
FLJ10470 fis, clone NT2RP2000032, weakly similar to RAS
SUPPRESSOR PROTEIN 1. ).
Length = 682
Score = 72.5 bits (170), Expect = 2e-12
Identities = 48/186 (25%), Positives = 82/186 (44%), Gaps = 2/186 (1%)
Frame = +2
Query: 149 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFP--VEXXXXXXXXXXXXXXXXXXX 322
+ L L E+ IP +++ ++ L L N I +
Sbjct: 462 AELELQNCELERIPHAIFSLSNLQELDLKSNNIRTIEEIISFQHLKRLTCLKLWHNKIVT 521
Query: 323 XPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
P I ++KNL +L S N L L + L+KL + + IP EIG L L
Sbjct: 522 IPPSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQNLQHL 581
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 682
GN++ +P+++ KLR L L N I +LP+ + +++ L L+ N L++ P+ +
Sbjct: 582 HITGNKVDILPKQLFKCIKLRTLNLGQNCITSLPEKVGQLSQLTQLELKGNCLDRLPAQL 641
Query: 683 LKCKEL 700
+C+ L
Sbjct: 642 GQCRML 647
Score = 67.3 bits (157), Expect = 6e-11
Identities = 45/161 (27%), Positives = 79/161 (49%), Gaps = 3/161 (1%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIG---LKEIPKEIGKLTQLD 496
P I +L NL L+L N + I EI + L+ C ++ + IP I + L+
Sbjct: 475 PHAIFSLSNLQELDLKSNNIRT-IEEIISFQHLKRLTCLKLWHNKIVTIPPSITHVKNLE 533
Query: 497 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 676
+ N+L+++P + SL KLR L + N I +P + + L H ++ N+++ P
Sbjct: 534 SLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQNLQHLHITGNKVDILPK 593
Query: 677 SILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSN 799
+ KC +L L L N I+S+P + + L ++L+ N
Sbjct: 594 QLFKCIKLRTLNLGQNCITSLPEKV--GQLSQLTQLELKGN 632
>BC108252-1|AAI08253.1| 532|Homo sapiens LRRC8E protein protein.
Length = 532
Score = 72.1 bits (169), Expect = 2e-12
Identities = 41/122 (33%), Positives = 58/122 (47%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P + L++L L LSYN L L ++G L + GL +P E+G L L
Sbjct: 382 PEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLA 441
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
N L+ +PEE+ KLR L L +NQ+ L + + AL L+ NRLE P +
Sbjct: 442 LSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVGALRALSRLELKGNRLEALPEELG 501
Query: 686 KC 691
C
Sbjct: 502 NC 503
Score = 61.7 bits (143), Expect = 3e-09
Identities = 42/153 (27%), Positives = 66/153 (43%), Gaps = 3/153 (1%)
Frame = +2
Query: 173 EITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKN 352
+I +P + +E LYL NK+ P + P E+G L+N
Sbjct: 377 QIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVGLLQN 436
Query: 353 LVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI 532
L +L LSYN L L E+ KL L ++ +G L L +GN L+ +
Sbjct: 437 LQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVGALRALSRLELKGNRLEAL 496
Query: 533 PEEMTSLAKLR--WLTLENNQIETLP-DTMDRM 622
PEE+ + L+ L +E+ + LP + D+M
Sbjct: 497 PEELGNCGGLKKAGLLVEDTLYQGLPAEVRDKM 529
Score = 60.1 bits (139), Expect = 1e-08
Identities = 34/122 (27%), Positives = 62/122 (50%)
Frame = +2
Query: 434 WCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM 613
W N+I +P+ + KL L+ N+L+T+P ++ + LR L + +N + +LP +
Sbjct: 374 WHNQIAY--VPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEV 431
Query: 614 DRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLR 793
+ L H L N LE P + C++L L L NQ+S + ++ + L ++L+
Sbjct: 432 GLLQNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHV--GALRALSRLELK 489
Query: 794 SN 799
N
Sbjct: 490 GN 491
Score = 52.8 bits (121), Expect = 1e-06
Identities = 39/139 (28%), Positives = 67/139 (48%), Gaps = 2/139 (1%)
Frame = +2
Query: 395 IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMT--SLAKLRW 568
+ ++ L +LE C GL+ IP + L L + N L++I E ++ KL
Sbjct: 314 LKKLAALRELELVAC---GLERIPHAVFSLGALQELDLKDNHLRSIEEILSFQHCRKLVT 370
Query: 569 LTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPAN 748
L L +NQI +P+ + ++ +L L N+LE PS + C L L ++ N + S+P
Sbjct: 371 LRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPP- 429
Query: 749 LDTSLVPGLXMIDLRSNPI 805
+ L+ L + L N +
Sbjct: 430 -EVGLLQNLQHLALSYNAL 447
Score = 52.4 bits (120), Expect = 2e-06
Identities = 36/147 (24%), Positives = 65/147 (44%)
Frame = +2
Query: 206 CLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPL 385
C ++ L L N+I+ P P+++G L L++S+N L
Sbjct: 365 CRKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGL 424
Query: 386 NVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLR 565
+ L PE+G L+ L+ + L+ +P+E+ +L T N+L + + +L L
Sbjct: 425 HSLPPEVGLLQNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVGALRALS 484
Query: 566 WLTLENNQIETLPDTMDRMTALVHCNL 646
L L+ N++E LP+ + L L
Sbjct: 485 RLELKGNRLEALPEELGNCGGLKKAGL 511
>BC070089-1|AAH70089.1| 796|Homo sapiens leucine rich repeat
containing 8 family, member E protein.
Length = 796
Score = 72.1 bits (169), Expect = 2e-12
Identities = 41/122 (33%), Positives = 58/122 (47%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P + L++L L LSYN L L ++G L + GL +P E+G L L
Sbjct: 646 PEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLA 705
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
N L+ +PEE+ KLR L L +NQ+ L + + AL L+ NRLE P +
Sbjct: 706 LSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVGALRALSRLELKGNRLEALPEELG 765
Query: 686 KC 691
C
Sbjct: 766 NC 767
Score = 61.7 bits (143), Expect = 3e-09
Identities = 42/153 (27%), Positives = 66/153 (43%), Gaps = 3/153 (1%)
Frame = +2
Query: 173 EITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKN 352
+I +P + +E LYL NK+ P + P E+G L+N
Sbjct: 641 QIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVGLLQN 700
Query: 353 LVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI 532
L +L LSYN L L E+ KL L ++ +G L L +GN L+ +
Sbjct: 701 LQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVGALRALSRLELKGNRLEAL 760
Query: 533 PEEMTSLAKLR--WLTLENNQIETLP-DTMDRM 622
PEE+ + L+ L +E+ + LP + D+M
Sbjct: 761 PEELGNCGGLKKAGLLVEDTLYQGLPAEVRDKM 793
Score = 60.1 bits (139), Expect = 1e-08
Identities = 34/122 (27%), Positives = 62/122 (50%)
Frame = +2
Query: 434 WCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM 613
W N+I +P+ + KL L+ N+L+T+P ++ + LR L + +N + +LP +
Sbjct: 638 WHNQIAY--VPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEV 695
Query: 614 DRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLR 793
+ L H L N LE P + C++L L L NQ+S + ++ + L ++L+
Sbjct: 696 GLLQNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHV--GALRALSRLELK 753
Query: 794 SN 799
N
Sbjct: 754 GN 755
Score = 52.8 bits (121), Expect = 1e-06
Identities = 39/139 (28%), Positives = 67/139 (48%), Gaps = 2/139 (1%)
Frame = +2
Query: 395 IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMT--SLAKLRW 568
+ ++ L +LE C GL+ IP + L L + N L++I E ++ KL
Sbjct: 578 LKKLAALRELELVAC---GLERIPHAVFSLGALQELDLKDNHLRSIEEILSFQHCRKLVT 634
Query: 569 LTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPAN 748
L L +NQI +P+ + ++ +L L N+LE PS + C L L ++ N + S+P
Sbjct: 635 LRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPP- 693
Query: 749 LDTSLVPGLXMIDLRSNPI 805
+ L+ L + L N +
Sbjct: 694 -EVGLLQNLQHLALSYNAL 711
Score = 52.4 bits (120), Expect = 2e-06
Identities = 36/147 (24%), Positives = 65/147 (44%)
Frame = +2
Query: 206 CLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPL 385
C ++ L L N+I+ P P+++G L L++S+N L
Sbjct: 629 CRKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGL 688
Query: 386 NVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLR 565
+ L PE+G L+ L+ + L+ +P+E+ +L T N+L + + +L L
Sbjct: 689 HSLPPEVGLLQNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVGALRALS 748
Query: 566 WLTLENNQIETLPDTMDRMTALVHCNL 646
L L+ N++E LP+ + L L
Sbjct: 749 RLELKGNRLEALPEELGNCGGLKKAGL 775
>BC022216-1|AAH22216.2| 592|Homo sapiens LRRC8E protein protein.
Length = 592
Score = 72.1 bits (169), Expect = 2e-12
Identities = 41/122 (33%), Positives = 58/122 (47%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P + L++L L LSYN L L ++G L + GL +P E+G L L
Sbjct: 442 PEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLA 501
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
N L+ +PEE+ KLR L L +NQ+ L + + AL L+ NRLE P +
Sbjct: 502 LSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVGALRALSRLELKGNRLEALPEELG 561
Query: 686 KC 691
C
Sbjct: 562 NC 563
Score = 61.7 bits (143), Expect = 3e-09
Identities = 42/153 (27%), Positives = 66/153 (43%), Gaps = 3/153 (1%)
Frame = +2
Query: 173 EITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKN 352
+I +P + +E LYL NK+ P + P E+G L+N
Sbjct: 437 QIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVGLLQN 496
Query: 353 LVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI 532
L +L LSYN L L E+ KL L ++ +G L L +GN L+ +
Sbjct: 497 LQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVGALRALSRLELKGNRLEAL 556
Query: 533 PEEMTSLAKLR--WLTLENNQIETLP-DTMDRM 622
PEE+ + L+ L +E+ + LP + D+M
Sbjct: 557 PEELGNCGGLKKAGLLVEDTLYQGLPAEVRDKM 589
Score = 60.1 bits (139), Expect = 1e-08
Identities = 34/122 (27%), Positives = 62/122 (50%)
Frame = +2
Query: 434 WCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM 613
W N+I +P+ + KL L+ N+L+T+P ++ + LR L + +N + +LP +
Sbjct: 434 WHNQIAY--VPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEV 491
Query: 614 DRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLR 793
+ L H L N LE P + C++L L L NQ+S + ++ + L ++L+
Sbjct: 492 GLLQNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHV--GALRALSRLELK 549
Query: 794 SN 799
N
Sbjct: 550 GN 551
Score = 52.8 bits (121), Expect = 1e-06
Identities = 39/139 (28%), Positives = 67/139 (48%), Gaps = 2/139 (1%)
Frame = +2
Query: 395 IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMT--SLAKLRW 568
+ ++ L +LE C GL+ IP + L L + N L++I E ++ KL
Sbjct: 374 LKKLAALRELELVAC---GLERIPHAVFSLGALQELDLKDNHLRSIEEILSFQHCRKLVT 430
Query: 569 LTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPAN 748
L L +NQI +P+ + ++ +L L N+LE PS + C L L ++ N + S+P
Sbjct: 431 LRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPP- 489
Query: 749 LDTSLVPGLXMIDLRSNPI 805
+ L+ L + L N +
Sbjct: 490 -EVGLLQNLQHLALSYNAL 507
Score = 52.4 bits (120), Expect = 2e-06
Identities = 36/147 (24%), Positives = 65/147 (44%)
Frame = +2
Query: 206 CLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPL 385
C ++ L L N+I+ P P+++G L L++S+N L
Sbjct: 425 CRKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGL 484
Query: 386 NVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLR 565
+ L PE+G L+ L+ + L+ +P+E+ +L T N+L + + +L L
Sbjct: 485 HSLPPEVGLLQNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVGALRALS 544
Query: 566 WLTLENNQIETLPDTMDRMTALVHCNL 646
L L+ N++E LP+ + L L
Sbjct: 545 RLELKGNRLEALPEELGNCGGLKKAGL 571
>AY358137-1|AAQ88504.1| 255|Homo sapiens VKGE9338 protein.
Length = 255
Score = 72.1 bits (169), Expect = 2e-12
Identities = 34/106 (32%), Positives = 61/106 (57%), Gaps = 2/106 (1%)
Frame = +2
Query: 440 NRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDR 619
+++G+ PK I +L+ +D N ++ IP+ ++ LRWL L +N I+ LP+++ +
Sbjct: 35 SKMGITTFPKCILRLSDMDELDLSRNLIRKIPDSISKFQNLRWLDLHSNYIDKLPESIGQ 94
Query: 620 MTALVHCNLRNNRLEQ--FPSSILKCKELMFLQLNSNQISSVPANL 751
MT+L++ N+ NNRL P + + K + + L N + SVP L
Sbjct: 95 MTSLLYLNVSNNRLTSNGLPVELKQLKNIRAVNLGLNHLDSVPTTL 140
Score = 42.3 bits (95), Expect = 0.002
Identities = 21/93 (22%), Positives = 50/93 (53%)
Frame = +2
Query: 521 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 700
+ T P+ + L+ + L L N I +PD++ + L +L +N +++ P SI + L
Sbjct: 39 ITTFPKCILRLSDMDELDLSRNLIRKIPDSISKFQNLRWLDLHSNYIDKLPESIGQMTSL 98
Query: 701 MFLQLNSNQISSVPANLDTSLVPGLXMIDLRSN 799
++L +++N+++S ++ + + ++L N
Sbjct: 99 LYLNVSNNRLTSNGLPVELKQLKNIRAVNLGLN 131
Score = 35.5 bits (78), Expect = 0.24
Identities = 31/123 (25%), Positives = 47/123 (38%), Gaps = 2/123 (1%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFP--VEXXXXXXXXXXXXXXXXXXXXP 328
L L+ I +IP + + L LH N I P + P
Sbjct: 55 LDLSRNLIRKIPDSISKFQNLRWLDLHSNYIDKLPESIGQMTSLLYLNVSNNRLTSNGLP 114
Query: 329 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGA 508
E+ LKN+ +NL N L+ + +G L++L + L IP I KL +L
Sbjct: 115 VELKQLKNIRAVNLGLNHLDSVPTTLGALKELHEVGLHDNLLNNIPVSISKLPKLKKLNI 174
Query: 509 RGN 517
+ N
Sbjct: 175 KRN 177
>AL834474-1|CAD39133.1| 622|Homo sapiens hypothetical protein
protein.
Length = 622
Score = 72.1 bits (169), Expect = 2e-12
Identities = 41/122 (33%), Positives = 58/122 (47%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P + L++L L LSYN L L ++G L + GL +P E+G L L
Sbjct: 472 PEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLA 531
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
N L+ +PEE+ KLR L L +NQ+ L + + AL L+ NRLE P +
Sbjct: 532 LSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVGALRALSRLELKGNRLEALPEELG 591
Query: 686 KC 691
C
Sbjct: 592 NC 593
Score = 61.7 bits (143), Expect = 3e-09
Identities = 42/153 (27%), Positives = 66/153 (43%), Gaps = 3/153 (1%)
Frame = +2
Query: 173 EITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKN 352
+I +P + +E LYL NK+ P + P E+G L+N
Sbjct: 467 QIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVGLLQN 526
Query: 353 LVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI 532
L +L LSYN L L E+ KL L ++ +G L L +GN L+ +
Sbjct: 527 LQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVGALRALSRLELKGNRLEAL 586
Query: 533 PEEMTSLAKLR--WLTLENNQIETLP-DTMDRM 622
PEE+ + L+ L +E+ + LP + D+M
Sbjct: 587 PEELGNCGGLKKAGLLVEDTLYQGLPAEVRDKM 619
Score = 60.1 bits (139), Expect = 1e-08
Identities = 34/122 (27%), Positives = 62/122 (50%)
Frame = +2
Query: 434 WCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM 613
W N+I +P+ + KL L+ N+L+T+P ++ + LR L + +N + +LP +
Sbjct: 464 WHNQIAY--VPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEV 521
Query: 614 DRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLR 793
+ L H L N LE P + C++L L L NQ+S + ++ + L ++L+
Sbjct: 522 GLLQNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHV--GALRALSRLELK 579
Query: 794 SN 799
N
Sbjct: 580 GN 581
Score = 52.8 bits (121), Expect = 1e-06
Identities = 39/139 (28%), Positives = 67/139 (48%), Gaps = 2/139 (1%)
Frame = +2
Query: 395 IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMT--SLAKLRW 568
+ ++ L +LE C GL+ IP + L L + N L++I E ++ KL
Sbjct: 404 LKKLAALRELELVAC---GLERIPHAVFSLGALQELDLKDNHLRSIEEILSFQHCRKLVT 460
Query: 569 LTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPAN 748
L L +NQI +P+ + ++ +L L N+LE PS + C L L ++ N + S+P
Sbjct: 461 LRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPP- 519
Query: 749 LDTSLVPGLXMIDLRSNPI 805
+ L+ L + L N +
Sbjct: 520 -EVGLLQNLQHLALSYNAL 537
Score = 52.4 bits (120), Expect = 2e-06
Identities = 36/147 (24%), Positives = 65/147 (44%)
Frame = +2
Query: 206 CLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPL 385
C ++ L L N+I+ P P+++G L L++S+N L
Sbjct: 455 CRKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGL 514
Query: 386 NVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLR 565
+ L PE+G L+ L+ + L+ +P+E+ +L T N+L + + +L L
Sbjct: 515 HSLPPEVGLLQNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVGALRALS 574
Query: 566 WLTLENNQIETLPDTMDRMTALVHCNL 646
L L+ N++E LP+ + L L
Sbjct: 575 RLELKGNRLEALPEELGNCGGLKKAGL 601
>AK027073-1|BAB15648.1| 444|Homo sapiens protein ( Homo sapiens
cDNA: FLJ23420 fis, clone HEP22352. ).
Length = 444
Score = 72.1 bits (169), Expect = 2e-12
Identities = 41/122 (33%), Positives = 58/122 (47%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P + L++L L LSYN L L ++G L + GL +P E+G L L
Sbjct: 294 PEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLA 353
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
N L+ +PEE+ KLR L L +NQ+ L + + AL L+ NRLE P +
Sbjct: 354 LSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVGALRALSRLELKGNRLEALPEELG 413
Query: 686 KC 691
C
Sbjct: 414 NC 415
Score = 61.7 bits (143), Expect = 3e-09
Identities = 42/153 (27%), Positives = 66/153 (43%), Gaps = 3/153 (1%)
Frame = +2
Query: 173 EITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKN 352
+I +P + +E LYL NK+ P + P E+G L+N
Sbjct: 289 QIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVGLLQN 348
Query: 353 LVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI 532
L +L LSYN L L E+ KL L ++ +G L L +GN L+ +
Sbjct: 349 LQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVGALRALSRLELKGNRLEAL 408
Query: 533 PEEMTSLAKLR--WLTLENNQIETLP-DTMDRM 622
PEE+ + L+ L +E+ + LP + D+M
Sbjct: 409 PEELGNCGGLKKAGLLVEDTLYQGLPAEVRDKM 441
Score = 60.1 bits (139), Expect = 1e-08
Identities = 34/122 (27%), Positives = 62/122 (50%)
Frame = +2
Query: 434 WCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM 613
W N+I +P+ + KL L+ N+L+T+P ++ + LR L + +N + +LP +
Sbjct: 286 WHNQIAY--VPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEV 343
Query: 614 DRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLR 793
+ L H L N LE P + C++L L L NQ+S + ++ + L ++L+
Sbjct: 344 GLLQNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHV--GALRALSRLELK 401
Query: 794 SN 799
N
Sbjct: 402 GN 403
Score = 52.8 bits (121), Expect = 1e-06
Identities = 39/139 (28%), Positives = 67/139 (48%), Gaps = 2/139 (1%)
Frame = +2
Query: 395 IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMT--SLAKLRW 568
+ ++ L +LE C GL+ IP + L L + N L++I E ++ KL
Sbjct: 226 LKKLAALRELELVAC---GLERIPHAVFSLGALQELDLKDNHLRSIEEILSFQHCRKLVT 282
Query: 569 LTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPAN 748
L L +NQI +P+ + ++ +L L N+LE PS + C L L ++ N + S+P
Sbjct: 283 LRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPP- 341
Query: 749 LDTSLVPGLXMIDLRSNPI 805
+ L+ L + L N +
Sbjct: 342 -EVGLLQNLQHLALSYNAL 359
Score = 52.4 bits (120), Expect = 2e-06
Identities = 36/147 (24%), Positives = 65/147 (44%)
Frame = +2
Query: 206 CLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPL 385
C ++ L L N+I+ P P+++G L L++S+N L
Sbjct: 277 CRKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGL 336
Query: 386 NVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLR 565
+ L PE+G L+ L+ + L+ +P+E+ +L T N+L + + +L L
Sbjct: 337 HSLPPEVGLLQNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVGALRALS 396
Query: 566 WLTLENNQIETLPDTMDRMTALVHCNL 646
L L+ N++E LP+ + L L
Sbjct: 397 RLELKGNRLEALPEELGNCGGLKKAGL 423
>U80184-1|AAC02796.1| 1269|Homo sapiens FLII protein.
Length = 1269
Score = 70.1 bits (164), Expect = 9e-12
Identities = 46/162 (28%), Positives = 83/162 (51%), Gaps = 3/162 (1%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPE-IGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
PT + L NL +++LS N L +PE + L L + + E+ I + ++T
Sbjct: 216 PTSLEGLSNLADVDLSCNDLT-RVPECLYTLPSLRRLNLSSNQITELSLCIDQWVHVETL 274
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIET--LPDTMDRMTALVHCNLRNNRLEQFPS 676
N+L ++P + L+KL+ L L +N+++ LP + ++T L NN LE P
Sbjct: 275 NLSRNQLTSLPSAICKLSKLKKLYLNSNKLDFDGLPSGIGKLTNLEEFMAANNNLELVPE 334
Query: 677 SILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNP 802
S+ +C +L L LN N + ++P + + + ++D+R NP
Sbjct: 335 SLCRCPKLRKLVLNKNHLVTLPEAI--HFLTEIEVLDVRENP 374
Score = 59.7 bits (138), Expect = 1e-08
Identities = 61/230 (26%), Positives = 94/230 (40%), Gaps = 5/230 (2%)
Frame = +2
Query: 56 NLPSLKCVPX*NSSVSNHXXXXXXXXXXXXXSRLSLNGFEITEIPGLLYTCLEVEHLYLH 235
+LPSL+ + +S+ N S L L+ ++TE P L + L L
Sbjct: 77 SLPSLRAIVARANSLKN-SGVPDDIFKLDDLSVLDLSHNQLTECPRELENAKNMLVLNLS 135
Query: 236 KNKISIFPVEXXXXXXXXXXXXXXXXXXXX-PTEIGNLKNLVNLNLSYNPLNVL----IP 400
N I P + P ++ L +L L L+ NPL +P
Sbjct: 136 HNSIDTIPNQLFINLTDLLYLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLP 195
Query: 401 EIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLE 580
+ L+ L R +P + L+ L N+L +PE + +L LR L L
Sbjct: 196 AMTALQTLHLRSTQRTQ-SNLPTSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLNLS 254
Query: 581 NNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQI 730
+NQI L +D+ + NL N+L PS+I K +L L LNSN++
Sbjct: 255 SNQITELSLCIDQWVHVETLNLSRNQLTSLPSAICKLSKLKKLYLNSNKL 304
Score = 50.0 bits (114), Expect = 1e-05
Identities = 43/198 (21%), Positives = 87/198 (43%), Gaps = 4/198 (2%)
Frame = +2
Query: 164 NGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIG- 340
N + + +P ++ ++ L L N+++ P E P ++
Sbjct: 89 NSLKNSGVPDDIFKLDDLSVLDLSHNQLTECPRELENAKNMLVLNLSHNSIDTIPNQLFI 148
Query: 341 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIP-KEIGKLTQLDTFGARGN 517
NL +L+ L+LS N L L P++ L L+ N L +++ +T L T R
Sbjct: 149 NLTDLLYLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLPAMTALQTLHLRST 208
Query: 518 EL--KTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 691
+ +P + L+ L + L N + +P+ + + +L NL +N++ + I +
Sbjct: 209 QRTQSNLPTSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLNLSSNQITELSLCIDQW 268
Query: 692 KELMFLQLNSNQISSVPA 745
+ L L+ NQ++S+P+
Sbjct: 269 VHVETLNLSRNQLTSLPS 286
Score = 41.1 bits (92), Expect = 0.005
Identities = 24/102 (23%), Positives = 44/102 (43%), Gaps = 2/102 (1%)
Frame = +2
Query: 512 GNELKT--IPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
GN+ K PE + ++ LRWL L + LP+ + + L H ++ +N L +
Sbjct: 17 GNDFKGGYFPENVKAMTSLRWLKLNRTGLCYLPEELAALQKLEHLSVSHNNLTTLHGELS 76
Query: 686 KCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICE 811
L + +N + + D + L ++DL N + E
Sbjct: 77 SLPSLRAIVARANSLKNSGVPDDIFKLDDLSVLDLSHNQLTE 118
>U01184-1|AAC03568.1| 1268|Homo sapiens flightless-I homolog
protein.
Length = 1268
Score = 70.1 bits (164), Expect = 9e-12
Identities = 46/162 (28%), Positives = 83/162 (51%), Gaps = 3/162 (1%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPE-IGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
PT + L NL +++LS N L +PE + L L + + E+ I + ++T
Sbjct: 215 PTSLEGLSNLADVDLSCNDLT-RVPECLYTLPSLRRLNLSSNQITELSLCIDQWVHVETL 273
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIET--LPDTMDRMTALVHCNLRNNRLEQFPS 676
N+L ++P + L+KL+ L L +N+++ LP + ++T L NN LE P
Sbjct: 274 NLSRNQLTSLPSAICKLSKLKKLYLNSNKLDFDGLPSGIGKLTNLEEFMAANNNLELVPE 333
Query: 677 SILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNP 802
S+ +C +L L LN N + ++P + + + ++D+R NP
Sbjct: 334 SLCRCPKLRKLVLNKNHLVTLPEAI--HFLTEIEVLDVRENP 373
Score = 59.7 bits (138), Expect = 1e-08
Identities = 61/230 (26%), Positives = 94/230 (40%), Gaps = 5/230 (2%)
Frame = +2
Query: 56 NLPSLKCVPX*NSSVSNHXXXXXXXXXXXXXSRLSLNGFEITEIPGLLYTCLEVEHLYLH 235
+LPSL+ + +S+ N S L L+ ++TE P L + L L
Sbjct: 76 SLPSLRAIVARANSLKN-SGVPDDIFKLDDLSVLDLSHNQLTECPRELENAKNMLVLNLS 134
Query: 236 KNKISIFPVEXXXXXXXXXXXXXXXXXXXX-PTEIGNLKNLVNLNLSYNPLNVL----IP 400
N I P + P ++ L +L L L+ NPL +P
Sbjct: 135 HNSIDTIPNQLFINLTDLLYLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLP 194
Query: 401 EIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLE 580
+ L+ L R +P + L+ L N+L +PE + +L LR L L
Sbjct: 195 AMTALQTLHLRSTQRTQ-SNLPTSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLNLS 253
Query: 581 NNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQI 730
+NQI L +D+ + NL N+L PS+I K +L L LNSN++
Sbjct: 254 SNQITELSLCIDQWVHVETLNLSRNQLTSLPSAICKLSKLKKLYLNSNKL 303
Score = 50.0 bits (114), Expect = 1e-05
Identities = 43/198 (21%), Positives = 87/198 (43%), Gaps = 4/198 (2%)
Frame = +2
Query: 164 NGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIG- 340
N + + +P ++ ++ L L N+++ P E P ++
Sbjct: 88 NSLKNSGVPDDIFKLDDLSVLDLSHNQLTECPRELENAKNMLVLNLSHNSIDTIPNQLFI 147
Query: 341 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIP-KEIGKLTQLDTFGARGN 517
NL +L+ L+LS N L L P++ L L+ N L +++ +T L T R
Sbjct: 148 NLTDLLYLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLPAMTALQTLHLRST 207
Query: 518 EL--KTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 691
+ +P + L+ L + L N + +P+ + + +L NL +N++ + I +
Sbjct: 208 QRTQSNLPTSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLNLSSNQITELSLCIDQW 267
Query: 692 KELMFLQLNSNQISSVPA 745
+ L L+ NQ++S+P+
Sbjct: 268 VHVETLNLSRNQLTSLPS 285
Score = 41.1 bits (92), Expect = 0.005
Identities = 24/102 (23%), Positives = 44/102 (43%), Gaps = 2/102 (1%)
Frame = +2
Query: 512 GNELKT--IPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
GN+ K PE + ++ LRWL L + LP+ + + L H ++ +N L +
Sbjct: 16 GNDFKGGYFPENVKAMTSLRWLKLNRTGLCYLPEELAALQKLEHLSVSHNNLTTLHGELS 75
Query: 686 KCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICE 811
L + +N + + D + L ++DL N + E
Sbjct: 76 SLPSLRAIVARANSLKNSGVPDDIFKLDDLSVLDLSHNQLTE 117
>BC025300-1|AAH25300.1| 1269|Homo sapiens flightless I homolog
(Drosophila) protein.
Length = 1269
Score = 70.1 bits (164), Expect = 9e-12
Identities = 46/162 (28%), Positives = 83/162 (51%), Gaps = 3/162 (1%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPE-IGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
PT + L NL +++LS N L +PE + L L + + E+ I + ++T
Sbjct: 216 PTSLEGLSNLADVDLSCNDLT-RVPECLYTLPSLRRLNLSSNQITELSLCIDQWVHVETL 274
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIET--LPDTMDRMTALVHCNLRNNRLEQFPS 676
N+L ++P + L+KL+ L L +N+++ LP + ++T L NN LE P
Sbjct: 275 NLSRNQLTSLPSAICKLSKLKKLYLNSNKLDFDGLPSGIGKLTNLEEFMAANNNLELVPE 334
Query: 677 SILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNP 802
S+ +C +L L LN N + ++P + + + ++D+R NP
Sbjct: 335 SLCRCPKLRKLVLNKNHLVTLPEAI--HFLTEIEVLDVRENP 374
Score = 59.7 bits (138), Expect = 1e-08
Identities = 61/230 (26%), Positives = 94/230 (40%), Gaps = 5/230 (2%)
Frame = +2
Query: 56 NLPSLKCVPX*NSSVSNHXXXXXXXXXXXXXSRLSLNGFEITEIPGLLYTCLEVEHLYLH 235
+LPSL+ + +S+ N S L L+ ++TE P L + L L
Sbjct: 77 SLPSLRAIVARANSLKN-SGVPDDIFKLDDLSVLDLSHNQLTECPRELENAKNMLVLNLS 135
Query: 236 KNKISIFPVEXXXXXXXXXXXXXXXXXXXX-PTEIGNLKNLVNLNLSYNPLNVL----IP 400
N I P + P ++ L +L L L+ NPL +P
Sbjct: 136 HNSIDTIPNQLFINLTDLLYLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLP 195
Query: 401 EIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLE 580
+ L+ L R +P + L+ L N+L +PE + +L LR L L
Sbjct: 196 AMTALQTLHLRSTQRTQ-SNLPTSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLNLS 254
Query: 581 NNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQI 730
+NQI L +D+ + NL N+L PS+I K +L L LNSN++
Sbjct: 255 SNQITELSLCIDQWVHVETLNLSRNQLTSLPSAICKLSKLKKLYLNSNKL 304
Score = 50.0 bits (114), Expect = 1e-05
Identities = 43/198 (21%), Positives = 87/198 (43%), Gaps = 4/198 (2%)
Frame = +2
Query: 164 NGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIG- 340
N + + +P ++ ++ L L N+++ P E P ++
Sbjct: 89 NSLKNSGVPDDIFKLDDLSVLDLSHNQLTECPRELENAKNMLVLNLSHNSIDTIPNQLFI 148
Query: 341 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIP-KEIGKLTQLDTFGARGN 517
NL +L+ L+LS N L L P++ L L+ N L +++ +T L T R
Sbjct: 149 NLTDLLYLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLPAMTALQTLHLRST 208
Query: 518 EL--KTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 691
+ +P + L+ L + L N + +P+ + + +L NL +N++ + I +
Sbjct: 209 QRTQSNLPTSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLNLSSNQITELSLCIDQW 268
Query: 692 KELMFLQLNSNQISSVPA 745
+ L L+ NQ++S+P+
Sbjct: 269 VHVETLNLSRNQLTSLPS 286
Score = 41.1 bits (92), Expect = 0.005
Identities = 24/102 (23%), Positives = 44/102 (43%), Gaps = 2/102 (1%)
Frame = +2
Query: 512 GNELKT--IPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
GN+ K PE + ++ LRWL L + LP+ + + L H ++ +N L +
Sbjct: 17 GNDFKGGYFPENVKAMTSLRWLKLNRTGLCYLPEELAALQKLEHLSVSHNNLTTLHGELS 76
Query: 686 KCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICE 811
L + +N + + D + L ++DL N + E
Sbjct: 77 SLPSLRAIVARANSLKNSGVPDDIFKLDDLSVLDLSHNQLTE 118
>AB208864-1|BAD92101.1| 1101|Homo sapiens flightless I homolog
variant protein.
Length = 1101
Score = 70.1 bits (164), Expect = 9e-12
Identities = 46/162 (28%), Positives = 83/162 (51%), Gaps = 3/162 (1%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPE-IGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
PT + L NL +++LS N L +PE + L L + + E+ I + ++T
Sbjct: 203 PTSLEGLSNLADVDLSCNDLT-RVPECLYTLPSLRRLNLSSNQITELSLCIDQWVHVETL 261
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIET--LPDTMDRMTALVHCNLRNNRLEQFPS 676
N+L ++P + L+KL+ L L +N+++ LP + ++T L NN LE P
Sbjct: 262 NLSRNQLTSLPSAICKLSKLKKLYLNSNKLDFDGLPSGIGKLTNLEEFMAANNNLELVPE 321
Query: 677 SILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNP 802
S+ +C +L L LN N + ++P + + + ++D+R NP
Sbjct: 322 SLCRCPKLRKLVLNKNHLVTLPEAI--HFLTEIEVLDVRENP 361
Score = 59.7 bits (138), Expect = 1e-08
Identities = 61/230 (26%), Positives = 94/230 (40%), Gaps = 5/230 (2%)
Frame = +2
Query: 56 NLPSLKCVPX*NSSVSNHXXXXXXXXXXXXXSRLSLNGFEITEIPGLLYTCLEVEHLYLH 235
+LPSL+ + +S+ N S L L+ ++TE P L + L L
Sbjct: 64 SLPSLRAIVARANSLKN-SGVPDDIFKLDDLSVLDLSHNQLTECPRELENAKNMLVLNLS 122
Query: 236 KNKISIFPVEXXXXXXXXXXXXXXXXXXXX-PTEIGNLKNLVNLNLSYNPLNVL----IP 400
N I P + P ++ L +L L L+ NPL +P
Sbjct: 123 HNSIDTIPNQLFINLTDLLYLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLP 182
Query: 401 EIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLE 580
+ L+ L R +P + L+ L N+L +PE + +L LR L L
Sbjct: 183 AMTALQTLHLRSTQRTQ-SNLPTSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLNLS 241
Query: 581 NNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQI 730
+NQI L +D+ + NL N+L PS+I K +L L LNSN++
Sbjct: 242 SNQITELSLCIDQWVHVETLNLSRNQLTSLPSAICKLSKLKKLYLNSNKL 291
Score = 50.0 bits (114), Expect = 1e-05
Identities = 43/198 (21%), Positives = 87/198 (43%), Gaps = 4/198 (2%)
Frame = +2
Query: 164 NGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIG- 340
N + + +P ++ ++ L L N+++ P E P ++
Sbjct: 76 NSLKNSGVPDDIFKLDDLSVLDLSHNQLTECPRELENAKNMLVLNLSHNSIDTIPNQLFI 135
Query: 341 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIP-KEIGKLTQLDTFGARGN 517
NL +L+ L+LS N L L P++ L L+ N L +++ +T L T R
Sbjct: 136 NLTDLLYLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLPAMTALQTLHLRST 195
Query: 518 EL--KTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 691
+ +P + L+ L + L N + +P+ + + +L NL +N++ + I +
Sbjct: 196 QRTQSNLPTSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLNLSSNQITELSLCIDQW 255
Query: 692 KELMFLQLNSNQISSVPA 745
+ L L+ NQ++S+P+
Sbjct: 256 VHVETLNLSRNQLTSLPS 273
Score = 41.1 bits (92), Expect = 0.005
Identities = 24/102 (23%), Positives = 44/102 (43%), Gaps = 2/102 (1%)
Frame = +2
Query: 512 GNELKT--IPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
GN+ K PE + ++ LRWL L + LP+ + + L H ++ +N L +
Sbjct: 4 GNDFKGGYFPENVKAMTSLRWLKLNRTGLCYLPEELAALQKLEHLSVSHNNLTTLHGELS 63
Query: 686 KCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICE 811
L + +N + + D + L ++DL N + E
Sbjct: 64 SLPSLRAIVARANSLKNSGVPDDIFKLDDLSVLDLSHNQLTE 105
>L12535-1|AAA60292.1| 277|Homo sapiens RSU-1 protein.
Length = 277
Score = 69.3 bits (162), Expect = 2e-11
Identities = 44/164 (26%), Positives = 71/164 (43%), Gaps = 2/164 (1%)
Frame = +2
Query: 197 LYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSY 376
L+T + L L NK+++ P PT+I +L+ L +LNL
Sbjct: 36 LFTLSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGM 95
Query: 377 NPLNVLIPEIGDLEKLEAF--WCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTS 550
N LN L G L LE N + +P LT L N+ + +P ++
Sbjct: 96 NRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGK 155
Query: 551 LAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 682
L KL+ L+L +N + +LP + +T L +++ NRL P +
Sbjct: 156 LTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPEL 199
Score = 63.3 bits (147), Expect = 1e-09
Identities = 45/140 (32%), Positives = 67/140 (47%), Gaps = 4/140 (2%)
Frame = +2
Query: 344 LKNLVNLNLSYNPLNVLIPEIGDLEKLEA--FWCNRIGLKEIPKEIGKLTQLDTFGARGN 517
L ++ L LS+N L ++ P I +L+ LE F+ N+I +E+P +I L +L N
Sbjct: 39 LSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQI--EELPTQISSLQKLKHLNLGMN 96
Query: 518 ELKTIPEEMTSLAKLRWLTLENNQI--ETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 691
L T+P SL L L L N + +LP +T L L +N E P I K
Sbjct: 97 RLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKL 156
Query: 692 KELMFLQLNSNQISSVPANL 751
+L L L N + S+P +
Sbjct: 157 TKLQILSLRDNDLISLPKEI 176
Score = 59.7 bits (138), Expect = 1e-08
Identities = 41/160 (25%), Positives = 73/160 (45%), Gaps = 2/160 (1%)
Frame = +2
Query: 149 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXP 328
++L L+ ++T +P + +E L N+I P + P
Sbjct: 43 TQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLP 102
Query: 329 TEIGNLKNLVNLNLSYNPL--NVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
G+L L L+L+YN L N L L L A + + + +P +IGKLT+L
Sbjct: 103 RGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQIL 162
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRM 622
R N+L ++P+E+ L +L+ L ++ N++ LP + +
Sbjct: 163 SLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPELGNL 202
Score = 43.6 bits (98), Expect = 9e-04
Identities = 25/88 (28%), Positives = 35/88 (39%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L+ N +PG + + LYL N I P + P E
Sbjct: 116 LTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKE 175
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLE 418
IG L L L++ N L VL PE+G+L+
Sbjct: 176 IGELTQLKELHIQGNRLTVLPPELGNLD 203
>CR541840-1|CAG46639.1| 277|Homo sapiens RSU1 protein.
Length = 277
Score = 69.3 bits (162), Expect = 2e-11
Identities = 44/164 (26%), Positives = 71/164 (43%), Gaps = 2/164 (1%)
Frame = +2
Query: 197 LYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSY 376
L+T + L L NK+++ P PT+I +L+ L +LNL
Sbjct: 36 LFTLSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGM 95
Query: 377 NPLNVLIPEIGDLEKLEAF--WCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTS 550
N LN L G L LE N + +P LT L N+ + +P ++
Sbjct: 96 NRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGK 155
Query: 551 LAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 682
L KL+ L+L +N + +LP + +T L +++ NRL P +
Sbjct: 156 LTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPEL 199
Score = 63.3 bits (147), Expect = 1e-09
Identities = 45/140 (32%), Positives = 67/140 (47%), Gaps = 4/140 (2%)
Frame = +2
Query: 344 LKNLVNLNLSYNPLNVLIPEIGDLEKLEA--FWCNRIGLKEIPKEIGKLTQLDTFGARGN 517
L ++ L LS+N L ++ P I +L+ LE F+ N+I +E+P +I L +L N
Sbjct: 39 LSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQI--EELPTQISSLQKLKHLNLGMN 96
Query: 518 ELKTIPEEMTSLAKLRWLTLENNQI--ETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 691
L T+P SL L L L N + +LP +T L L +N E P I K
Sbjct: 97 RLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKL 156
Query: 692 KELMFLQLNSNQISSVPANL 751
+L L L N + S+P +
Sbjct: 157 TKLQILSLRDNDLISLPKEI 176
Score = 59.7 bits (138), Expect = 1e-08
Identities = 41/160 (25%), Positives = 73/160 (45%), Gaps = 2/160 (1%)
Frame = +2
Query: 149 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXP 328
++L L+ ++T +P + +E L N+I P + P
Sbjct: 43 TQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLP 102
Query: 329 TEIGNLKNLVNLNLSYNPL--NVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
G+L L L+L+YN L N L L L A + + + +P +IGKLT+L
Sbjct: 103 RGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQIL 162
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRM 622
R N+L ++P+E+ L +L+ L ++ N++ LP + +
Sbjct: 163 SLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPELGNL 202
Score = 43.6 bits (98), Expect = 9e-04
Identities = 25/88 (28%), Positives = 35/88 (39%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L+ N +PG + + LYL N I P + P E
Sbjct: 116 LTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKE 175
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLE 418
IG L L L++ N L VL PE+G+L+
Sbjct: 176 IGELTQLKELHIQGNRLTVLPPELGNLD 203
>CR536521-1|CAG38758.1| 277|Homo sapiens RSU1 protein.
Length = 277
Score = 69.3 bits (162), Expect = 2e-11
Identities = 44/164 (26%), Positives = 71/164 (43%), Gaps = 2/164 (1%)
Frame = +2
Query: 197 LYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSY 376
L+T + L L NK+++ P PT+I +L+ L +LNL
Sbjct: 36 LFTLSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGM 95
Query: 377 NPLNVLIPEIGDLEKLEAF--WCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTS 550
N LN L G L LE N + +P LT L N+ + +P ++
Sbjct: 96 NRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGK 155
Query: 551 LAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 682
L KL+ L+L +N + +LP + +T L +++ NRL P +
Sbjct: 156 LTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPEL 199
Score = 63.3 bits (147), Expect = 1e-09
Identities = 45/140 (32%), Positives = 67/140 (47%), Gaps = 4/140 (2%)
Frame = +2
Query: 344 LKNLVNLNLSYNPLNVLIPEIGDLEKLEA--FWCNRIGLKEIPKEIGKLTQLDTFGARGN 517
L ++ L LS+N L ++ P I +L+ LE F+ N+I +E+P +I L +L N
Sbjct: 39 LSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQI--EELPTQISSLQKLKHLNLGMN 96
Query: 518 ELKTIPEEMTSLAKLRWLTLENNQI--ETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 691
L T+P SL L L L N + +LP +T L L +N E P I K
Sbjct: 97 RLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKL 156
Query: 692 KELMFLQLNSNQISSVPANL 751
+L L L N + S+P +
Sbjct: 157 TKLQILSLRDNDLISLPKEI 176
Score = 59.7 bits (138), Expect = 1e-08
Identities = 41/160 (25%), Positives = 73/160 (45%), Gaps = 2/160 (1%)
Frame = +2
Query: 149 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXP 328
++L L+ ++T +P + +E L N+I P + P
Sbjct: 43 TQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLP 102
Query: 329 TEIGNLKNLVNLNLSYNPL--NVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
G+L L L+L+YN L N L L L A + + + +P +IGKLT+L
Sbjct: 103 RGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQIL 162
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRM 622
R N+L ++P+E+ L +L+ L ++ N++ LP + +
Sbjct: 163 SLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPELGNL 202
Score = 43.6 bits (98), Expect = 9e-04
Identities = 25/88 (28%), Positives = 35/88 (39%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L+ N +PG + + LYL N I P + P E
Sbjct: 116 LTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKE 175
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLE 418
IG L L L++ N L VL PE+G+L+
Sbjct: 176 IGELTQLKELHIQGNRLTVLPPELGNLD 203
>BC015644-1|AAH15644.1| 277|Homo sapiens Ras suppressor protein 1
protein.
Length = 277
Score = 69.3 bits (162), Expect = 2e-11
Identities = 44/164 (26%), Positives = 71/164 (43%), Gaps = 2/164 (1%)
Frame = +2
Query: 197 LYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSY 376
L+T + L L NK+++ P PT+I +L+ L +LNL
Sbjct: 36 LFTLSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGM 95
Query: 377 NPLNVLIPEIGDLEKLEAF--WCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTS 550
N LN L G L LE N + +P LT L N+ + +P ++
Sbjct: 96 NRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGK 155
Query: 551 LAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 682
L KL+ L+L +N + +LP + +T L +++ NRL P +
Sbjct: 156 LTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPEL 199
Score = 63.3 bits (147), Expect = 1e-09
Identities = 45/140 (32%), Positives = 67/140 (47%), Gaps = 4/140 (2%)
Frame = +2
Query: 344 LKNLVNLNLSYNPLNVLIPEIGDLEKLEA--FWCNRIGLKEIPKEIGKLTQLDTFGARGN 517
L ++ L LS+N L ++ P I +L+ LE F+ N+I +E+P +I L +L N
Sbjct: 39 LSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQI--EELPTQISSLQKLKHLNLGMN 96
Query: 518 ELKTIPEEMTSLAKLRWLTLENNQI--ETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 691
L T+P SL L L L N + +LP +T L L +N E P I K
Sbjct: 97 RLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKL 156
Query: 692 KELMFLQLNSNQISSVPANL 751
+L L L N + S+P +
Sbjct: 157 TKLQILSLRDNDLISLPKEI 176
Score = 59.7 bits (138), Expect = 1e-08
Identities = 41/160 (25%), Positives = 73/160 (45%), Gaps = 2/160 (1%)
Frame = +2
Query: 149 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXP 328
++L L+ ++T +P + +E L N+I P + P
Sbjct: 43 TQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLP 102
Query: 329 TEIGNLKNLVNLNLSYNPL--NVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
G+L L L+L+YN L N L L L A + + + +P +IGKLT+L
Sbjct: 103 RGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQIL 162
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRM 622
R N+L ++P+E+ L +L+ L ++ N++ LP + +
Sbjct: 163 SLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPELGNL 202
Score = 43.6 bits (98), Expect = 9e-04
Identities = 25/88 (28%), Positives = 35/88 (39%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L+ N +PG + + LYL N I P + P E
Sbjct: 116 LTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKE 175
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLE 418
IG L L L++ N L VL PE+G+L+
Sbjct: 176 IGELTQLKELHIQGNRLTVLPPELGNLD 203
>BC008691-1|AAH08691.1| 277|Homo sapiens RSU1 protein protein.
Length = 277
Score = 69.3 bits (162), Expect = 2e-11
Identities = 44/164 (26%), Positives = 71/164 (43%), Gaps = 2/164 (1%)
Frame = +2
Query: 197 LYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSY 376
L+T + L L NK+++ P PT+I +L+ L +LNL
Sbjct: 36 LFTLSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGM 95
Query: 377 NPLNVLIPEIGDLEKLEAF--WCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTS 550
N LN L G L LE N + +P LT L N+ + +P ++
Sbjct: 96 NRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGK 155
Query: 551 LAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 682
L KL+ L+L +N + +LP + +T L +++ NRL P +
Sbjct: 156 LTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPEL 199
Score = 63.3 bits (147), Expect = 1e-09
Identities = 45/140 (32%), Positives = 67/140 (47%), Gaps = 4/140 (2%)
Frame = +2
Query: 344 LKNLVNLNLSYNPLNVLIPEIGDLEKLEA--FWCNRIGLKEIPKEIGKLTQLDTFGARGN 517
L ++ L LS+N L ++ P I +L+ LE F+ N+I +E+P +I L +L N
Sbjct: 39 LSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQI--EELPTQISSLQKLKHLNLGMN 96
Query: 518 ELKTIPEEMTSLAKLRWLTLENNQI--ETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 691
L T+P SL L L L N + +LP +T L L +N E P I K
Sbjct: 97 RLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKL 156
Query: 692 KELMFLQLNSNQISSVPANL 751
+L L L N + S+P +
Sbjct: 157 TKLQILSLRDNDLISLPKEI 176
Score = 59.7 bits (138), Expect = 1e-08
Identities = 41/160 (25%), Positives = 73/160 (45%), Gaps = 2/160 (1%)
Frame = +2
Query: 149 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXP 328
++L L+ ++T +P + +E L N+I P + P
Sbjct: 43 TQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLP 102
Query: 329 TEIGNLKNLVNLNLSYNPL--NVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
G+L L L+L+YN L N L L L A + + + +P +IGKLT+L
Sbjct: 103 RGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQIL 162
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRM 622
R N+L ++P+E+ L +L+ L ++ N++ LP + +
Sbjct: 163 SLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPELGNL 202
Score = 43.6 bits (98), Expect = 9e-04
Identities = 25/88 (28%), Positives = 35/88 (39%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L+ N +PG + + LYL N I P + P E
Sbjct: 116 LTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKE 175
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLE 418
IG L L L++ N L VL PE+G+L+
Sbjct: 176 IGELTQLKELHIQGNRLTVLPPELGNLD 203
>BC005993-1|AAH05993.1| 277|Homo sapiens Ras suppressor protein 1
protein.
Length = 277
Score = 69.3 bits (162), Expect = 2e-11
Identities = 44/164 (26%), Positives = 71/164 (43%), Gaps = 2/164 (1%)
Frame = +2
Query: 197 LYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSY 376
L+T + L L NK+++ P PT+I +L+ L +LNL
Sbjct: 36 LFTLSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGM 95
Query: 377 NPLNVLIPEIGDLEKLEAF--WCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTS 550
N LN L G L LE N + +P LT L N+ + +P ++
Sbjct: 96 NRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGK 155
Query: 551 LAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 682
L KL+ L+L +N + +LP + +T L +++ NRL P +
Sbjct: 156 LTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPEL 199
Score = 63.3 bits (147), Expect = 1e-09
Identities = 45/140 (32%), Positives = 67/140 (47%), Gaps = 4/140 (2%)
Frame = +2
Query: 344 LKNLVNLNLSYNPLNVLIPEIGDLEKLEA--FWCNRIGLKEIPKEIGKLTQLDTFGARGN 517
L ++ L LS+N L ++ P I +L+ LE F+ N+I +E+P +I L +L N
Sbjct: 39 LSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQI--EELPTQISSLQKLKHLNLGMN 96
Query: 518 ELKTIPEEMTSLAKLRWLTLENNQI--ETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 691
L T+P SL L L L N + +LP +T L L +N E P I K
Sbjct: 97 RLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKL 156
Query: 692 KELMFLQLNSNQISSVPANL 751
+L L L N + S+P +
Sbjct: 157 TKLQILSLRDNDLISLPKEI 176
Score = 59.7 bits (138), Expect = 1e-08
Identities = 41/160 (25%), Positives = 73/160 (45%), Gaps = 2/160 (1%)
Frame = +2
Query: 149 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXP 328
++L L+ ++T +P + +E L N+I P + P
Sbjct: 43 TQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLP 102
Query: 329 TEIGNLKNLVNLNLSYNPL--NVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
G+L L L+L+YN L N L L L A + + + +P +IGKLT+L
Sbjct: 103 RGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQIL 162
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRM 622
R N+L ++P+E+ L +L+ L ++ N++ LP + +
Sbjct: 163 SLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPELGNL 202
Score = 43.6 bits (98), Expect = 9e-04
Identities = 25/88 (28%), Positives = 35/88 (39%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L+ N +PG + + LYL N I P + P E
Sbjct: 116 LTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKE 175
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLE 418
IG L L L++ N L VL PE+G+L+
Sbjct: 176 IGELTQLKELHIQGNRLTVLPPELGNLD 203
>AL365215-3|CAH73633.1| 277|Homo sapiens Ras suppressor protein 1
protein.
Length = 277
Score = 69.3 bits (162), Expect = 2e-11
Identities = 44/164 (26%), Positives = 71/164 (43%), Gaps = 2/164 (1%)
Frame = +2
Query: 197 LYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSY 376
L+T + L L NK+++ P PT+I +L+ L +LNL
Sbjct: 36 LFTLSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGM 95
Query: 377 NPLNVLIPEIGDLEKLEAF--WCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTS 550
N LN L G L LE N + +P LT L N+ + +P ++
Sbjct: 96 NRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGK 155
Query: 551 LAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 682
L KL+ L+L +N + +LP + +T L +++ NRL P +
Sbjct: 156 LTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPEL 199
Score = 63.3 bits (147), Expect = 1e-09
Identities = 45/140 (32%), Positives = 67/140 (47%), Gaps = 4/140 (2%)
Frame = +2
Query: 344 LKNLVNLNLSYNPLNVLIPEIGDLEKLEA--FWCNRIGLKEIPKEIGKLTQLDTFGARGN 517
L ++ L LS+N L ++ P I +L+ LE F+ N+I +E+P +I L +L N
Sbjct: 39 LSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQI--EELPTQISSLQKLKHLNLGMN 96
Query: 518 ELKTIPEEMTSLAKLRWLTLENNQI--ETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 691
L T+P SL L L L N + +LP +T L L +N E P I K
Sbjct: 97 RLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKL 156
Query: 692 KELMFLQLNSNQISSVPANL 751
+L L L N + S+P +
Sbjct: 157 TKLQILSLRDNDLISLPKEI 176
Score = 59.7 bits (138), Expect = 1e-08
Identities = 41/160 (25%), Positives = 73/160 (45%), Gaps = 2/160 (1%)
Frame = +2
Query: 149 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXP 328
++L L+ ++T +P + +E L N+I P + P
Sbjct: 43 TQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLP 102
Query: 329 TEIGNLKNLVNLNLSYNPL--NVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
G+L L L+L+YN L N L L L A + + + +P +IGKLT+L
Sbjct: 103 RGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQIL 162
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRM 622
R N+L ++P+E+ L +L+ L ++ N++ LP + +
Sbjct: 163 SLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPELGNL 202
Score = 43.6 bits (98), Expect = 9e-04
Identities = 25/88 (28%), Positives = 35/88 (39%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L+ N +PG + + LYL N I P + P E
Sbjct: 116 LTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKE 175
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLE 418
IG L L L++ N L VL PE+G+L+
Sbjct: 176 IGELTQLKELHIQGNRLTVLPPELGNLD 203
>BC036722-1|AAH36722.1| 261|Homo sapiens leucine rich repeat
containing 18 protein.
Length = 261
Score = 68.9 bits (161), Expect = 2e-11
Identities = 33/106 (31%), Positives = 60/106 (56%), Gaps = 2/106 (1%)
Frame = +2
Query: 440 NRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDR 619
+++G+ PK I +L+ +D N ++ IP+ ++ LRWL L +N I+ LP+++ +
Sbjct: 35 SKMGITTFPKCILRLSDMDELDLSRNLIRKIPDSISKFQNLRWLDLHSNYIDKLPESIGQ 94
Query: 620 MTALVHCNLRNNRLEQ--FPSSILKCKELMFLQLNSNQISSVPANL 751
MT+L++ N+ NNRL P + + K + + L N + SV L
Sbjct: 95 MTSLLYLNVSNNRLTSNGLPVELKQLKNIRAVNLGLNHLDSVSTTL 140
Score = 43.2 bits (97), Expect = 0.001
Identities = 22/99 (22%), Positives = 53/99 (53%)
Frame = +2
Query: 521 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 700
+ T P+ + L+ + L L N I +PD++ + L +L +N +++ P SI + L
Sbjct: 39 ITTFPKCILRLSDMDELDLSRNLIRKIPDSISKFQNLRWLDLHSNYIDKLPESIGQMTSL 98
Query: 701 MFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELS 817
++L +++N+++S ++ + + ++L N + +S
Sbjct: 99 LYLNVSNNRLTSNGLPVELKQLKNIRAVNLGLNHLDSVS 137
Score = 35.9 bits (79), Expect = 0.18
Identities = 31/123 (25%), Positives = 47/123 (38%), Gaps = 2/123 (1%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFP--VEXXXXXXXXXXXXXXXXXXXXP 328
L L+ I +IP + + L LH N I P + P
Sbjct: 55 LDLSRNLIRKIPDSISKFQNLRWLDLHSNYIDKLPESIGQMTSLLYLNVSNNRLTSNGLP 114
Query: 329 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGA 508
E+ LKN+ +NL N L+ + +G L++L + L IP I KL +L
Sbjct: 115 VELKQLKNIRAVNLGLNHLDSVSTTLGALKELHEVGLHDNLLNNIPVSISKLPKLKKLNI 174
Query: 509 RGN 517
+ N
Sbjct: 175 KRN 177
>BC107898-1|AAI07899.1| 280|Homo sapiens RSU1 protein protein.
Length = 280
Score = 66.5 bits (155), Expect = 1e-10
Identities = 43/162 (26%), Positives = 69/162 (42%), Gaps = 2/162 (1%)
Frame = +2
Query: 203 TCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNP 382
T + L L NK+++ P PT+I +L+ L +LNL N
Sbjct: 41 TLSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNR 100
Query: 383 LNVLIPEIGDLEKLEAF--WCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLA 556
LN L G L LE N + +P LT L N+ + +P ++ L
Sbjct: 101 LNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLT 160
Query: 557 KLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 682
KL+ L+L +N + +LP + +T L +++ NRL P +
Sbjct: 161 KLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPEL 202
Score = 63.3 bits (147), Expect = 1e-09
Identities = 45/140 (32%), Positives = 67/140 (47%), Gaps = 4/140 (2%)
Frame = +2
Query: 344 LKNLVNLNLSYNPLNVLIPEIGDLEKLEA--FWCNRIGLKEIPKEIGKLTQLDTFGARGN 517
L ++ L LS+N L ++ P I +L+ LE F+ N+I +E+P +I L +L N
Sbjct: 42 LSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQI--EELPTQISSLQKLKHLNLGMN 99
Query: 518 ELKTIPEEMTSLAKLRWLTLENNQI--ETLPDTMDRMTALVHCNLRNNRLEQFPSSILKC 691
L T+P SL L L L N + +LP +T L L +N E P I K
Sbjct: 100 RLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKL 159
Query: 692 KELMFLQLNSNQISSVPANL 751
+L L L N + S+P +
Sbjct: 160 TKLQILSLRDNDLISLPKEI 179
Score = 59.7 bits (138), Expect = 1e-08
Identities = 41/160 (25%), Positives = 73/160 (45%), Gaps = 2/160 (1%)
Frame = +2
Query: 149 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXP 328
++L L+ ++T +P + +E L N+I P + P
Sbjct: 46 TQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLP 105
Query: 329 TEIGNLKNLVNLNLSYNPL--NVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
G+L L L+L+YN L N L L L A + + + +P +IGKLT+L
Sbjct: 106 RGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQIL 165
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRM 622
R N+L ++P+E+ L +L+ L ++ N++ LP + +
Sbjct: 166 SLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPELGNL 205
Score = 43.6 bits (98), Expect = 9e-04
Identities = 25/88 (28%), Positives = 35/88 (39%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L+ N +PG + + LYL N I P + P E
Sbjct: 119 LTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKE 178
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLE 418
IG L L L++ N L VL PE+G+L+
Sbjct: 179 IGELTQLKELHIQGNRLTVLPPELGNLD 206
>BC129927-1|AAI29928.1| 1323|Homo sapiens PH domain and leucine rich
repeat protein phosphatase-like protein.
Length = 1323
Score = 66.1 bits (154), Expect = 1e-10
Identities = 49/159 (30%), Positives = 79/159 (49%), Gaps = 5/159 (3%)
Frame = +2
Query: 353 LVNLNLSYNPLN---VLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNEL 523
L LNLS+N L +L+ EI L +L CN G ++P +IG L L T GN L
Sbjct: 301 LKGLNLSHNKLGLFPILLCEISTLTELNLS-CN--GFHDLPSQIGNLLNLQTLCLDGNFL 357
Query: 524 KTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL-KCKEL 700
T+PEE+ +L +L L + N +P+ +++T L + N LE +L + +
Sbjct: 358 TTLPEELGNLQQLSSLGISFNNFSQIPEVYEKLTMLDRVVMAGNCLEVLNLGVLNRMNHI 417
Query: 701 MFLQLNSNQISS-VPANLDTSLVPGLXMIDLRSNPICEL 814
+ L N + + V NL+ + + +DLR N + +L
Sbjct: 418 KHVDLRMNHLKTMVIENLEGN--KHITHVDLRDNRLTDL 454
Score = 65.3 bits (152), Expect = 3e-10
Identities = 50/180 (27%), Positives = 83/180 (46%), Gaps = 2/180 (1%)
Frame = +2
Query: 197 LYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSY 376
LY +++ L L NK+ +FP+ P++IGNL NL L L
Sbjct: 295 LYKFSQLKGLNLSHNKLGLFPILLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDG 354
Query: 377 NPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP-EEMTSL 553
N L L E+G+L++L + + +IP+ KLT LD GN L+ + + +
Sbjct: 355 NFLTTLPEELGNLQQLSSLGISFNNFSQIPEVYEKLTMLDRVVMAGNCLEVLNLGVLNRM 414
Query: 554 AKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQI 730
++ + L N ++T+ + ++ + H +LR+NRL S L C L L NQ+
Sbjct: 415 NHIKHVDLRMNHLKTMVIENLEGNKHITHVDLRDNRLTDLDLSSL-C-SLEQLHCGRNQL 472
Score = 61.7 bits (143), Expect = 3e-09
Identities = 47/166 (28%), Positives = 77/166 (46%), Gaps = 2/166 (1%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P + + L LNLS N + L +IG+L L+ + L +P+E+G L QL + G
Sbjct: 315 PILLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNFLTTLPEELGNLQQLSSLG 374
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQFPSSI 682
N IPE L L + + N +E L ++RM + H +LR N L+
Sbjct: 375 ISFNNFSQIPEVYEKLTMLDRVVMAGNCLEVLNLGVLNRMNHIKHVDLRMNHLKTMVIEN 434
Query: 683 LK-CKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELS 817
L+ K + + L N+++ +LD S + L + N + EL+
Sbjct: 435 LEGNKHITHVDLRDNRLT----DLDLSSLCSLEQLHCGRNQLRELT 476
Score = 57.2 bits (132), Expect = 7e-08
Identities = 33/90 (36%), Positives = 50/90 (55%), Gaps = 1/90 (1%)
Frame = +2
Query: 560 LRWLTLENNQIETLPDT-MDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISS 736
LR L L NNQ++T P + ++++ L NL N+L+ P++I CK L L +SN IS
Sbjct: 646 LRILHLANNQLQTFPASKLNKLEQLEELNLSGNKLKTIPTTIANCKRLHTLVAHSNNISI 705
Query: 737 VPANLDTSLVPGLXMIDLRSNPICELSHPE 826
P L +P + +DL N + E+ PE
Sbjct: 706 FPEILQ---LPQIQFVDLSCNDLTEILIPE 732
Score = 49.2 bits (112), Expect = 2e-05
Identities = 53/221 (23%), Positives = 86/221 (38%), Gaps = 6/221 (2%)
Frame = +2
Query: 176 ITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 355
+TE+P + + L + L L N + P T NL
Sbjct: 537 LTEVPVRILSSLSLRKLMLGHNHVQNLPTLVEHIPLEVLDLQHNALTRLPDTLFSKALNL 596
Query: 356 VNLNLSYNPLNVLIPEIGDLEKLEA----FWCNRIGLKE-IPKEIGKLTQLDTFGARGNE 520
LN S N L L E L + N + + IP +G L L N+
Sbjct: 597 RYLNASANSLESLPSACTGEESLSMLQLLYLTNNLLTDQCIPVLVGHL-HLRILHLANNQ 655
Query: 521 LKTIP-EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKE 697
L+T P ++ L +L L L N+++T+P T+ L +N + FP IL+ +
Sbjct: 656 LQTFPASKLNKLEQLEELNLSGNKLKTIPTTIANCKRLHTLVAHSNNISIFP-EILQLPQ 714
Query: 698 LMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELSH 820
+ F+ L+ N ++ + + +L L +DL N L H
Sbjct: 715 IQFVDLSCNDLTEI--LIPEALPATLQDLDLTGNTNLVLEH 753
Score = 33.1 bits (72), Expect = 1.3
Identities = 23/85 (27%), Positives = 41/85 (48%), Gaps = 4/85 (4%)
Frame = +2
Query: 521 LKTIPEEMTSLAKLRWLTLENN--QIETLP--DTMDRMTALVHCNLRNNRLEQFPSSILK 688
L+ +PE + + +L L +N Q+E DT+ + + L NL +N+L FP + +
Sbjct: 261 LEEVPEHLFYSQDITYLNLRHNFMQLERPGGLDTLYKFSQLKGLNLSHNKLGLFPILLCE 320
Query: 689 CKELMFLQLNSNQISSVPANLDTSL 763
L L L+ N +P+ + L
Sbjct: 321 ISTLTELNLSCNGFHDLPSQIGNLL 345
Score = 31.9 bits (69), Expect = 2.9
Identities = 14/35 (40%), Positives = 20/35 (57%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFP 259
L+L+G ++ IP + C + L H N ISIFP
Sbjct: 673 LNLSGNKLKTIPTTIANCKRLHTLVAHSNNISIFP 707
Score = 30.3 bits (65), Expect = 8.9
Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 9/78 (11%)
Frame = +2
Query: 557 KLRWLTLENNQIETLPDTMDRMTA---------LVHCNLRNNRLEQFPSSILKCKELMFL 709
+LR LTL + TL + +R+TA L +L N LE P + K++ L
Sbjct: 471 QLRELTLSGFSLRTLYASSNRLTAVNVYPVPSLLTFLDLSRNLLECVPDWACEAKKIEVL 530
Query: 710 QLNSNQISSVPANLDTSL 763
++ N ++ VP + +SL
Sbjct: 531 DVSYNLLTEVPVRILSSL 548
>BC035267-1|AAH35267.1| 723|Homo sapiens PHLPPL protein protein.
Length = 723
Score = 66.1 bits (154), Expect = 1e-10
Identities = 49/159 (30%), Positives = 79/159 (49%), Gaps = 5/159 (3%)
Frame = +2
Query: 353 LVNLNLSYNPLN---VLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNEL 523
L LNLS+N L +L+ EI L +L CN G ++P +IG L L T GN L
Sbjct: 39 LKGLNLSHNKLGLFPILLCEISTLTELNLS-CN--GFHDLPSQIGNLLNLQTLCLDGNFL 95
Query: 524 KTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL-KCKEL 700
T+PEE+ +L +L L + N +P+ +++T L + N LE +L + +
Sbjct: 96 TTLPEELGNLQQLSSLGISFNNFSQIPEVYEKLTMLDRVVMAGNCLEVLNLGVLNRMNHI 155
Query: 701 MFLQLNSNQISS-VPANLDTSLVPGLXMIDLRSNPICEL 814
+ L N + + V NL+ + + +DLR N + +L
Sbjct: 156 KHVDLRMNHLKTMVIENLEGN--KHITHVDLRDNRLTDL 192
Score = 65.3 bits (152), Expect = 3e-10
Identities = 50/180 (27%), Positives = 83/180 (46%), Gaps = 2/180 (1%)
Frame = +2
Query: 197 LYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSY 376
LY +++ L L NK+ +FP+ P++IGNL NL L L
Sbjct: 33 LYKFSQLKGLNLSHNKLGLFPILLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDG 92
Query: 377 NPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP-EEMTSL 553
N L L E+G+L++L + + +IP+ KLT LD GN L+ + + +
Sbjct: 93 NFLTTLPEELGNLQQLSSLGISFNNFSQIPEVYEKLTMLDRVVMAGNCLEVLNLGVLNRM 152
Query: 554 AKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQI 730
++ + L N ++T+ + ++ + H +LR+NRL S L C L L NQ+
Sbjct: 153 NHIKHVDLRMNHLKTMVIENLEGNKHITHVDLRDNRLTDLDLSSL-C-SLEQLHCGRNQL 210
Score = 61.7 bits (143), Expect = 3e-09
Identities = 47/166 (28%), Positives = 77/166 (46%), Gaps = 2/166 (1%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P + + L LNLS N + L +IG+L L+ + L +P+E+G L QL + G
Sbjct: 53 PILLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNFLTTLPEELGNLQQLSSLG 112
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQFPSSI 682
N IPE L L + + N +E L ++RM + H +LR N L+
Sbjct: 113 ISFNNFSQIPEVYEKLTMLDRVVMAGNCLEVLNLGVLNRMNHIKHVDLRMNHLKTMVIEN 172
Query: 683 LK-CKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELS 817
L+ K + + L N+++ +LD S + L + N + EL+
Sbjct: 173 LEGNKHITHVDLRDNRLT----DLDLSSLCSLEQLHCGRNQLRELT 214
Score = 57.6 bits (133), Expect = 5e-08
Identities = 33/90 (36%), Positives = 50/90 (55%), Gaps = 1/90 (1%)
Frame = +2
Query: 560 LRWLTLENNQIETLPDT-MDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISS 736
LR L L NNQ++T P + ++++ L NL N+L+ P++I CK L L +SN IS
Sbjct: 384 LRILRLANNQLQTFPASKLNKLEQLEELNLSGNKLKTIPTTIANCKRLHTLVAHSNNISI 443
Query: 737 VPANLDTSLVPGLXMIDLRSNPICELSHPE 826
P L +P + +DL N + E+ PE
Sbjct: 444 FPEILQ---LPQIQFVDLSCNDLTEILIPE 470
Score = 49.2 bits (112), Expect = 2e-05
Identities = 53/221 (23%), Positives = 86/221 (38%), Gaps = 6/221 (2%)
Frame = +2
Query: 176 ITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 355
+TE+P + + L + L L N + P T NL
Sbjct: 275 LTEVPVRILSSLSLRKLMLGHNHVQNLPTLVEHIPLEVLDLQHNALTRLPDTLFSKALNL 334
Query: 356 VNLNLSYNPLNVLIPEIGDLEKLEA----FWCNRIGLKE-IPKEIGKLTQLDTFGARGNE 520
LN S N L L E L + N + + IP +G L L N+
Sbjct: 335 RYLNASANSLESLPSACTGEESLSMLQLLYLTNNLLTDQCIPVLVGHL-HLRILRLANNQ 393
Query: 521 LKTIP-EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKE 697
L+T P ++ L +L L L N+++T+P T+ L +N + FP IL+ +
Sbjct: 394 LQTFPASKLNKLEQLEELNLSGNKLKTIPTTIANCKRLHTLVAHSNNISIFP-EILQLPQ 452
Query: 698 LMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELSH 820
+ F+ L+ N ++ + + +L L +DL N L H
Sbjct: 453 IQFVDLSCNDLTEI--LIPEALPATLQDLDLTGNTNLVLEH 491
Score = 31.9 bits (69), Expect = 2.9
Identities = 14/35 (40%), Positives = 20/35 (57%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFP 259
L+L+G ++ IP + C + L H N ISIFP
Sbjct: 411 LNLSGNKLKTIPTTIANCKRLHTLVAHSNNISIFP 445
Score = 31.5 bits (68), Expect = 3.9
Identities = 22/82 (26%), Positives = 39/82 (47%), Gaps = 4/82 (4%)
Frame = +2
Query: 530 IPEEMTSLAKLRWLTLENN--QIETLP--DTMDRMTALVHCNLRNNRLEQFPSSILKCKE 697
+PE + + +L L +N Q+E DT+ + + L NL +N+L FP + +
Sbjct: 2 VPEHLFYSQDITYLNLRHNFMQLERPGGLDTLYKFSQLKGLNLSHNKLGLFPILLCEIST 61
Query: 698 LMFLQLNSNQISSVPANLDTSL 763
L L L+ N +P+ + L
Sbjct: 62 LTELNLSCNGFHDLPSQIGNLL 83
Score = 30.3 bits (65), Expect = 8.9
Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 9/78 (11%)
Frame = +2
Query: 557 KLRWLTLENNQIETLPDTMDRMTA---------LVHCNLRNNRLEQFPSSILKCKELMFL 709
+LR LTL + TL + +R+TA L +L N LE P + K++ L
Sbjct: 209 QLRELTLSGFSLRTLYASSNRLTAVNVYPVPSLLTFLDLSRNLLECVPDWACEAKKIEVL 268
Query: 710 QLNSNQISSVPANLDTSL 763
++ N ++ VP + +SL
Sbjct: 269 DVSYNLLTEVPVRILSSL 286
>AB023148-1|BAA76775.2| 1258|Homo sapiens KIAA0931 protein protein.
Length = 1258
Score = 66.1 bits (154), Expect = 1e-10
Identities = 49/159 (30%), Positives = 79/159 (49%), Gaps = 5/159 (3%)
Frame = +2
Query: 353 LVNLNLSYNPLN---VLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNEL 523
L LNLS+N L +L+ EI L +L CN G ++P +IG L L T GN L
Sbjct: 303 LKGLNLSHNKLGLFPILLCEISTLTELNLS-CN--GFHDLPSQIGNLLNLQTLCLDGNFL 359
Query: 524 KTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL-KCKEL 700
T+PEE+ +L +L L + N +P+ +++T L + N LE +L + +
Sbjct: 360 TTLPEELGNLQQLSSLGISFNNFSQIPEVYEKLTMLDRVVMAGNCLEVLNLGVLNRMNHI 419
Query: 701 MFLQLNSNQISS-VPANLDTSLVPGLXMIDLRSNPICEL 814
+ L N + + V NL+ + + +DLR N + +L
Sbjct: 420 KHVDLRMNHLKTMVIENLEGN--KHITHVDLRDNRLTDL 456
Score = 65.3 bits (152), Expect = 3e-10
Identities = 50/180 (27%), Positives = 83/180 (46%), Gaps = 2/180 (1%)
Frame = +2
Query: 197 LYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSY 376
LY +++ L L NK+ +FP+ P++IGNL NL L L
Sbjct: 297 LYKFSQLKGLNLSHNKLGLFPILLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDG 356
Query: 377 NPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP-EEMTSL 553
N L L E+G+L++L + + +IP+ KLT LD GN L+ + + +
Sbjct: 357 NFLTTLPEELGNLQQLSSLGISFNNFSQIPEVYEKLTMLDRVVMAGNCLEVLNLGVLNRM 416
Query: 554 AKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQI 730
++ + L N ++T+ + ++ + H +LR+NRL S L C L L NQ+
Sbjct: 417 NHIKHVDLRMNHLKTMVIENLEGNKHITHVDLRDNRLTDLDLSSL-C-SLEQLHCGRNQL 474
Score = 61.7 bits (143), Expect = 3e-09
Identities = 47/166 (28%), Positives = 77/166 (46%), Gaps = 2/166 (1%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P + + L LNLS N + L +IG+L L+ + L +P+E+G L QL + G
Sbjct: 317 PILLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNFLTTLPEELGNLQQLSSLG 376
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQFPSSI 682
N IPE L L + + N +E L ++RM + H +LR N L+
Sbjct: 377 ISFNNFSQIPEVYEKLTMLDRVVMAGNCLEVLNLGVLNRMNHIKHVDLRMNHLKTMVIEN 436
Query: 683 LK-CKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELS 817
L+ K + + L N+++ +LD S + L + N + EL+
Sbjct: 437 LEGNKHITHVDLRDNRLT----DLDLSSLCSLEQLHCGRNQLRELT 478
Score = 56.4 bits (130), Expect = 1e-07
Identities = 47/166 (28%), Positives = 76/166 (45%), Gaps = 8/166 (4%)
Frame = +2
Query: 353 LVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI 532
L L+LS N L + + +K+E + L E+P I L N ++ +
Sbjct: 506 LTFLDLSRNLLECVPDWACEAKKIEVLDVSYNLLTEVPVRILSSLSLRKLMLGHNHVQNL 565
Query: 533 PEEMTSLAKLRWLTLENNQIETLPDTM--------DRMTALVHCNLRNNRLEQFPSSILK 688
P + + L L L++N + LPDT+ +++ L NL N+L+ P++I
Sbjct: 566 PTLVEHIP-LEVLDLQHNALTRLPDTLFSKALNKLNKLEQLEELNLSGNKLKTIPTTIAN 624
Query: 689 CKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELSHPE 826
CK L L +SN IS P L +P + +DL N + E+ PE
Sbjct: 625 CKRLHTLVAHSNNISIFPEILQ---LPQIQFVDLSCNDLTEILIPE 667
Score = 33.1 bits (72), Expect = 1.3
Identities = 23/85 (27%), Positives = 41/85 (48%), Gaps = 4/85 (4%)
Frame = +2
Query: 521 LKTIPEEMTSLAKLRWLTLENN--QIETLP--DTMDRMTALVHCNLRNNRLEQFPSSILK 688
L+ +PE + + +L L +N Q+E DT+ + + L NL +N+L FP + +
Sbjct: 263 LEEVPEHLFYSQDITYLNLRHNFMQLERPGGLDTLYKFSQLKGLNLSHNKLGLFPILLCE 322
Query: 689 CKELMFLQLNSNQISSVPANLDTSL 763
L L L+ N +P+ + L
Sbjct: 323 ISTLTELNLSCNGFHDLPSQIGNLL 347
Score = 31.9 bits (69), Expect = 2.9
Identities = 14/35 (40%), Positives = 20/35 (57%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFP 259
L+L+G ++ IP + C + L H N ISIFP
Sbjct: 608 LNLSGNKLKTIPTTIANCKRLHTLVAHSNNISIFP 642
Score = 30.3 bits (65), Expect = 8.9
Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 9/78 (11%)
Frame = +2
Query: 557 KLRWLTLENNQIETLPDTMDRMTA---------LVHCNLRNNRLEQFPSSILKCKELMFL 709
+LR LTL + TL + +R+TA L +L N LE P + K++ L
Sbjct: 473 QLRELTLSGFSLRTLYASSNRLTAVNVYPVPSLLTFLDLSRNLLECVPDWACEAKKIEVL 532
Query: 710 QLNSNQISSVPANLDTSL 763
++ N ++ VP + +SL
Sbjct: 533 DVSYNLLTEVPVRILSSL 550
>AK021896-1|BAB13929.1| 197|Homo sapiens protein ( Homo sapiens
cDNA FLJ11834 fis, clone HEMBA1006583, weakly similar to
Drosophila melanogaster Scribble (scrib) mRNA. ).
Length = 197
Score = 64.5 bits (150), Expect = 4e-10
Identities = 40/135 (29%), Positives = 62/135 (45%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P + L L L LS N + L PEI + +L +R + EIP+ I L
Sbjct: 52 PEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNEIPEIPESISFCKALQVAD 111
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
GN L +PE L L L++ + +++LP+ + + L LR N L P S+
Sbjct: 112 FSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPDSLT 171
Query: 686 KCKELMFLQLNSNQI 730
+ + L L L +N+I
Sbjct: 172 QLRRLEELDLGNNEI 186
Score = 58.0 bits (134), Expect = 4e-08
Identities = 31/116 (26%), Positives = 60/116 (51%)
Frame = +2
Query: 452 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 631
L+E+P++ +L +L G NE++ +P E+ + +L L + N+I +P+++ AL
Sbjct: 48 LRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNEIPEIPESISFCKAL 107
Query: 632 VHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSN 799
+ N L + P S + + L L +N + S+P N+ + L ++LR N
Sbjct: 108 QVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGN--LYNLASLELREN 161
Score = 57.2 bits (132), Expect = 7e-08
Identities = 29/95 (30%), Positives = 50/95 (52%), Gaps = 1/95 (1%)
Frame = +2
Query: 461 IPKEIGKLTQ-LDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVH 637
+P+EI + + L+ N+L+ +PE+ L KLR L L +N+I+ LP + LV
Sbjct: 27 VPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVE 86
Query: 638 CNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVP 742
++ N + + P SI CK L + N ++ +P
Sbjct: 87 LDVSRNEIPEIPESISFCKALQVADFSGNPLTRLP 121
Score = 53.2 bits (122), Expect = 1e-06
Identities = 40/160 (25%), Positives = 70/160 (43%)
Frame = +2
Query: 347 KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELK 526
++L L L N L L + L KL + ++ +P EI QL NE+
Sbjct: 36 RSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNEIP 95
Query: 527 TIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMF 706
IPE ++ L+ N + LP++ + L ++ + L+ P +I L
Sbjct: 96 EIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLAS 155
Query: 707 LQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELSHPE 826
L+L N ++ +P +L + + L +DL +N I L+ E
Sbjct: 156 LELRENLLTYLPDSL--TQLRRLEELDLGNNEIYNLNQLE 193
>AK000338-1|BAA91094.1| 384|Homo sapiens protein ( Homo sapiens
cDNA FLJ20331 fis, clone HEP10410. ).
Length = 384
Score = 64.5 bits (150), Expect = 4e-10
Identities = 41/135 (30%), Positives = 67/135 (49%), Gaps = 2/135 (1%)
Frame = +2
Query: 326 PTEIGNLKNLVN-LNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
P + LK +V+ ++LS+N L+ + E+ L+KL L +P+E+ L +L T
Sbjct: 223 PKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLVRLQTI 282
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQFPSS 679
N K +PE + + L + + NNQ+ ++ P M M L +L+NN L Q P
Sbjct: 283 NLSFNRFKMLPEVLYRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPPE 342
Query: 680 ILKCKELMFLQLNSN 724
+ C L L L+ N
Sbjct: 343 LGNCVNLRTLLLDGN 357
Score = 61.7 bits (143), Expect = 3e-09
Identities = 40/132 (30%), Positives = 72/132 (54%), Gaps = 1/132 (0%)
Frame = +2
Query: 413 LEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQI 592
+++L+ CN L+ IP E+ + L+ R N+L+ +PE S + L+ L + NQI
Sbjct: 1 MKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFLPE-FPSCSLLKELHVGENQI 59
Query: 593 ETLP-DTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVP 769
E L + + + +++ +LR+N+L+ P I+ + L L L++N ISS+P +L
Sbjct: 60 EMLEAEHLKHLNSILVLDLRDNKLKSVPDEIILLRSLERLDLSNNDISSLPYSLGNL--- 116
Query: 770 GLXMIDLRSNPI 805
L + L NP+
Sbjct: 117 HLKFLALEGNPL 128
Score = 57.2 bits (132), Expect = 7e-08
Identities = 35/122 (28%), Positives = 63/122 (51%), Gaps = 1/122 (0%)
Frame = +2
Query: 452 LKEIPKEIGKLTQL-DTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTA 628
L EIPK + +L ++ N+L I E+ L KL +L L NN + +LP+ M+ +
Sbjct: 219 LCEIPKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLVR 278
Query: 629 LVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPIC 808
L NL NR + P + + L + +++NQ+ SV ++ L +DL++N +
Sbjct: 279 LQTINLSFNRFKMLPEVLYRIFTLETILISNNQVGSVDPQ-KMKMMENLTTLDLQNNDLL 337
Query: 809 EL 814
++
Sbjct: 338 QI 339
Score = 36.3 bits (80), Expect = 0.14
Identities = 33/132 (25%), Positives = 50/132 (37%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L N + IP L +E LYL +NK+ P
Sbjct: 7 LDCNSNLLETIPPELAGMESLELLYLRRNKLRFLPEFPSCSLLKELHVGENQIEMLEAEH 66
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
+ +L +++ L+L N L + EI L LE + + +P +G L L G
Sbjct: 67 LKHLNSILVLDLRDNKLKSVPDEIILLRSLERLDLSNNDISSLPYSLGNL-HLKFLALEG 125
Query: 515 NELKTIPEEMTS 550
N L+TI E+ S
Sbjct: 126 NPLRTIRREIIS 137
Score = 31.5 bits (68), Expect = 3.9
Identities = 22/80 (27%), Positives = 34/80 (42%), Gaps = 1/80 (1%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKI-SIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
LS N F++ +P +LY +E + + N++ S+ P + P
Sbjct: 284 LSFNRFKM--LPEVLYRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPP 341
Query: 332 EIGNLKNLVNLNLSYNPLNV 391
E+GN NL L L NP V
Sbjct: 342 ELGNCVNLRTLLLDGNPFRV 361
>BC113973-1|AAI13974.1| 803|Homo sapiens factor for adipocyte
differentiation 158 protein.
Length = 803
Score = 64.1 bits (149), Expect = 6e-10
Identities = 44/169 (26%), Positives = 79/169 (46%), Gaps = 2/169 (1%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVL--IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDT 499
P + +L +L L+L N L + I L KL + IP+ I KLT L+
Sbjct: 605 PHAVFSLLSLQELDLKENNLKSIEEIVSFQHLRKLTVLKLWHNSITYIPEHIKKLTSLER 664
Query: 500 FGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSS 679
N+++ +P + K+R+L L N I +P + + +L + ++ N++E P
Sbjct: 665 LSFSHNKIEVLPSHLFLCNKIRYLDLSYNDIRFIPPEIGVLQSLQYFSITCNKVESLPDE 724
Query: 680 ILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELSHPE 826
+ CK+L L++ N +S + + L L +D++ N E+ PE
Sbjct: 725 LYFCKKLKTLKIGKNSLSVLSPKIGNLLF--LSYLDVKGNHF-EILPPE 770
Score = 58.8 bits (136), Expect = 2e-08
Identities = 41/186 (22%), Positives = 78/186 (41%), Gaps = 2/186 (1%)
Frame = +2
Query: 149 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFP--VEXXXXXXXXXXXXXXXXXXX 322
+ L L ++ IP +++ L ++ L L +N + V
Sbjct: 592 TELELVHCDLERIPHAVFSLLSLQELDLKENNLKSIEEIVSFQHLRKLTVLKLWHNSITY 651
Query: 323 XPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
P I L +L L+ S+N + VL + K+ + ++ IP EIG L L F
Sbjct: 652 IPEHIKKLTSLERLSFSHNKIEVLPSHLFLCNKIRYLDLSYNDIRFIPPEIGVLQSLQYF 711
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 682
N+++++P+E+ KL+ L + N + L + + L + +++ N E P +
Sbjct: 712 SITCNKVESLPDELYFCKKLKTLKIGKNSLSVLSPKIGNLLFLSYLDVKGNHFEILPPEL 771
Query: 683 LKCKEL 700
C+ L
Sbjct: 772 GDCRAL 777
Score = 49.6 bits (113), Expect = 1e-05
Identities = 39/157 (24%), Positives = 64/157 (40%), Gaps = 4/157 (2%)
Frame = +2
Query: 224 LYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPE 403
L L N I+ P P+ + + L+LSYN + + PE
Sbjct: 642 LKLWHNSITYIPEHIKKLTSLERLSFSHNKIEVLPSHLFLCNKIRYLDLSYNDIRFIPPE 701
Query: 404 IGDLEKLEAF--WCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTL 577
IG L+ L+ F CN++ + +P E+ +L T N L + ++ +L L +L +
Sbjct: 702 IGVLQSLQYFSITCNKV--ESLPDELYFCKKLKTLKIGKNSLSVLSPKIGNLLFLSYLDV 759
Query: 578 ENNQIETLPDTMDRMTALVHCNL--RNNRLEQFPSSI 682
+ N E LP + AL L + E PS +
Sbjct: 760 KGNHFEILPPELGDCRALKRAGLVVEDALFETLPSDV 796
>AB081509-1|BAB86303.1| 803|Homo sapiens AD158 protein.
Length = 803
Score = 64.1 bits (149), Expect = 6e-10
Identities = 44/169 (26%), Positives = 79/169 (46%), Gaps = 2/169 (1%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVL--IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDT 499
P + +L +L L+L N L + I L KL + IP+ I KLT L+
Sbjct: 605 PHAVFSLLSLQELDLKENNLKSIEEIVSFQHLRKLTVLKLWHNSITYIPEHIKKLTSLER 664
Query: 500 FGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSS 679
N+++ +P + K+R+L L N I +P + + +L + ++ N++E P
Sbjct: 665 LSFSHNKIEVLPSHLFLCNKIRYLDLSYNDIRFIPPEIGVLQSLQYFSITCNKVESLPDE 724
Query: 680 ILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELSHPE 826
+ CK+L L++ N +S + + L L +D++ N E+ PE
Sbjct: 725 LYFCKKLKTLKIGKNSLSVLSPKIGNLLF--LSYLDVKGNHF-EILPPE 770
Score = 58.8 bits (136), Expect = 2e-08
Identities = 41/186 (22%), Positives = 78/186 (41%), Gaps = 2/186 (1%)
Frame = +2
Query: 149 SRLSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFP--VEXXXXXXXXXXXXXXXXXXX 322
+ L L ++ IP +++ L ++ L L +N + V
Sbjct: 592 TELELVHCDLERIPHAVFSLLSLQELDLKENNLKSIEEIVSFQHLRKLTVLKLWHNSITY 651
Query: 323 XPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
P I L +L L+ S+N + VL + K+ + ++ IP EIG L L F
Sbjct: 652 IPEHIKKLTSLERLSFSHNKIEVLPSHLFLCNKIRYLDLSYNDIRFIPPEIGVLQSLQYF 711
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 682
N+++++P+E+ KL+ L + N + L + + L + +++ N E P +
Sbjct: 712 SITCNKVESLPDELYFCKKLKTLKIGKNSLSVLSPKIGNLLFLSYLDVKGNHFEILPPEL 771
Query: 683 LKCKEL 700
C+ L
Sbjct: 772 GDCRAL 777
Score = 49.6 bits (113), Expect = 1e-05
Identities = 39/157 (24%), Positives = 64/157 (40%), Gaps = 4/157 (2%)
Frame = +2
Query: 224 LYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVLIPE 403
L L N I+ P P+ + + L+LSYN + + PE
Sbjct: 642 LKLWHNSITYIPEHIKKLTSLERLSFSHNKIEVLPSHLFLCNKIRYLDLSYNDIRFIPPE 701
Query: 404 IGDLEKLEAF--WCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTL 577
IG L+ L+ F CN++ + +P E+ +L T N L + ++ +L L +L +
Sbjct: 702 IGVLQSLQYFSITCNKV--ESLPDELYFCKKLKTLKIGKNSLSVLSPKIGNLLFLSYLDV 759
Query: 578 ENNQIETLPDTMDRMTALVHCNL--RNNRLEQFPSSI 682
+ N E LP + AL L + E PS +
Sbjct: 760 KGNHFEILPPELGDCRALKRAGLVVEDALFETLPSDV 796
>BC013757-1|AAH13757.1| 403|Homo sapiens LRRC58 protein protein.
Length = 403
Score = 63.3 bits (147), Expect = 1e-09
Identities = 49/166 (29%), Positives = 77/166 (46%), Gaps = 5/166 (3%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P + L+ L L+L N L + EI +L+ LE + +KEIP E+G L L+
Sbjct: 168 PASLLELRALQTLSLGGNQLQSIPAEIENLQSLECLYLGGNFIKEIPPELGNLPSLNYLV 227
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRL-EQFPSSI 682
N++++IP +++ L LR L+L NN + LP + + L +LR N L +F +
Sbjct: 228 LCDNKIQSIPPQLSQLHSLRSLSLHNNLLTYLPREILNLIHLEELSLRGNPLVVRFVRDL 287
Query: 683 L----KCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPIC 808
EL + IS P +L +L+ L NP C
Sbjct: 288 TYDPPTLLELAARTIKIRNISYTPYDLPGNLLRYLGSASNCPNPKC 333
Score = 59.3 bits (137), Expect = 2e-08
Identities = 33/117 (28%), Positives = 64/117 (54%)
Frame = +2
Query: 455 KEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALV 634
+E+P + +L L T GN+L++IP E+ +L L L L N I+ +P + + +L
Sbjct: 165 QEVPASLLELRALQTLSLGGNQLQSIPAEIENLQSLECLYLGGNFIKEIPPELGNLPSLN 224
Query: 635 HCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
+ L +N+++ P + + L L L++N ++ +P + +L+ L + LR NP+
Sbjct: 225 YLVLCDNKIQSIPPQLSQLHSLRSLSLHNNLLTYLPREI-LNLI-HLEELSLRGNPL 279
Score = 48.4 bits (110), Expect = 3e-05
Identities = 31/108 (28%), Positives = 53/108 (49%), Gaps = 7/108 (6%)
Frame = +2
Query: 452 LKEIPKEIGK-LTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQI---ETLPDTMDR 619
L +P+ +G L GN L + E+ +L LR L +NN++ LP + +
Sbjct: 88 LVSLPRALGSGFPHLQLLDVSGNALTALGPELLALRGLRTLLAKNNRLGGPSALPKGLAQ 147
Query: 620 MT---ALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLD 754
+L NL N ++ P+S+L+ + L L L NQ+ S+PA ++
Sbjct: 148 SPLCRSLQVLNLSGNCFQEVPASLLELRALQTLSLGGNQLQSIPAEIE 195
Score = 47.6 bits (108), Expect = 6e-05
Identities = 33/123 (26%), Positives = 51/123 (41%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L+L+G E+P L ++ L L N++ P E P E
Sbjct: 157 LNLSGNCFQEVPASLLELRALQTLSLGGNQLQSIPAEIENLQSLECLYLGGNFIKEIPPE 216
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
+GNL +L L L N + + P++ L L + + L +P+EI L L+ RG
Sbjct: 217 LGNLPSLNYLVLCDNKIQSIPPQLSQLHSLRSLSLHNNLLTYLPREILNLIHLEELSLRG 276
Query: 515 NEL 523
N L
Sbjct: 277 NPL 279
Score = 33.1 bits (72), Expect = 1.3
Identities = 26/79 (32%), Positives = 31/79 (39%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L G I EIP L + +L L NKI P + P E
Sbjct: 203 LYLGGNFIKEIPPELGNLPSLNYLVLCDNKIQSIPPQLSQLHSLRSLSLHNNLLTYLPRE 262
Query: 335 IGNLKNLVNLNLSYNPLNV 391
I NL +L L+L NPL V
Sbjct: 263 ILNLIHLEELSLRGNPLVV 281
>BC009239-1|AAH09239.1| 723|Homo sapiens leucine rich repeat and
sterile alpha motif containing 1 protein.
Length = 723
Score = 62.9 bits (146), Expect = 1e-09
Identities = 36/124 (29%), Positives = 59/124 (47%)
Frame = +2
Query: 341 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 520
+L + L+L N L L ++G L L+ R L ++P+ IG LTQL T + N+
Sbjct: 79 SLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNK 138
Query: 521 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 700
LK +P+ + L LR L + N+I+ LP + + L +L + + P +
Sbjct: 139 LKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPPREVCGAGTA 198
Query: 701 MFLQ 712
LQ
Sbjct: 199 AILQ 202
Score = 58.0 bits (134), Expect = 4e-08
Identities = 48/183 (26%), Positives = 82/183 (44%), Gaps = 8/183 (4%)
Frame = +2
Query: 155 LSLNGFEITEIP-GLLYTC--LEVEHLYLHKNKI-SIFP--VEXXXXXXXXXXXXXXXXX 316
L ++ E++EIP G TC L+ + L +H N + S+ P
Sbjct: 34 LDISKCELSEIPFGAFATCKVLQKKVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQL 93
Query: 317 XXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLD 496
P ++G L L LN+ N L L IG+L +L+ LKE+P +G+L L
Sbjct: 94 TALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSLR 153
Query: 497 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM--DRMTALVHCNLRNNRLEQF 670
T GNE++ +P+ + + L L+L+ + + P + A++ + + LE +
Sbjct: 154 TLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPPREVCGAGTAAILQFLCKESGLEYY 213
Query: 671 PSS 679
P S
Sbjct: 214 PPS 216
Score = 58.0 bits (134), Expect = 4e-08
Identities = 25/97 (25%), Positives = 54/97 (55%)
Frame = +2
Query: 452 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 631
L +P ++G+LT L N+L +P + +L +L+ L +++N+++ LPDT+ + +L
Sbjct: 93 LTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSL 152
Query: 632 VHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVP 742
N+ N +++ P + + L L L+++ + P
Sbjct: 153 RTLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPP 189
Score = 55.2 bits (127), Expect = 3e-07
Identities = 24/90 (26%), Positives = 50/90 (55%)
Frame = +2
Query: 482 LTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRL 661
L + N+L +P+++ L L+ L +E NQ+ LP ++ +T L N+++N+L
Sbjct: 80 LATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKL 139
Query: 662 EQFPSSILKCKELMFLQLNSNQISSVPANL 751
++ P ++ + + L L ++ N+I +P L
Sbjct: 140 KELPDTVGELRSLRTLNISGNEIQRLPQML 169
Score = 50.4 bits (115), Expect = 8e-06
Identities = 24/67 (35%), Positives = 39/67 (58%)
Frame = +2
Query: 542 MTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNS 721
+ SLA ++ L L +NQ+ LPD + ++TAL N+ N+L Q P SI +L L +
Sbjct: 77 LLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKD 136
Query: 722 NQISSVP 742
N++ +P
Sbjct: 137 NKLKELP 143
>AY358830-1|AAQ89189.1| 723|Homo sapiens leucine-rich protein
protein.
Length = 723
Score = 62.9 bits (146), Expect = 1e-09
Identities = 36/124 (29%), Positives = 59/124 (47%)
Frame = +2
Query: 341 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 520
+L + L+L N L L ++G L L+ R L ++P+ IG LTQL T + N+
Sbjct: 79 SLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNK 138
Query: 521 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 700
LK +P+ + L LR L + N+I+ LP + + L +L + + P +
Sbjct: 139 LKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPPREVCGAGTA 198
Query: 701 MFLQ 712
LQ
Sbjct: 199 AILQ 202
Score = 58.0 bits (134), Expect = 4e-08
Identities = 48/183 (26%), Positives = 82/183 (44%), Gaps = 8/183 (4%)
Frame = +2
Query: 155 LSLNGFEITEIP-GLLYTC--LEVEHLYLHKNKI-SIFP--VEXXXXXXXXXXXXXXXXX 316
L ++ E++EIP G TC L+ + L +H N + S+ P
Sbjct: 34 LDISKCELSEIPFGAFATCKVLQKKVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQL 93
Query: 317 XXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLD 496
P ++G L L LN+ N L L IG+L +L+ LKE+P +G+L L
Sbjct: 94 TALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSLR 153
Query: 497 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM--DRMTALVHCNLRNNRLEQF 670
T GNE++ +P+ + + L L+L+ + + P + A++ + + LE +
Sbjct: 154 TLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPPREVCGAGTAAILQFLCKESGLEYY 213
Query: 671 PSS 679
P S
Sbjct: 214 PPS 216
Score = 58.0 bits (134), Expect = 4e-08
Identities = 25/97 (25%), Positives = 54/97 (55%)
Frame = +2
Query: 452 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 631
L +P ++G+LT L N+L +P + +L +L+ L +++N+++ LPDT+ + +L
Sbjct: 93 LTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSL 152
Query: 632 VHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVP 742
N+ N +++ P + + L L L+++ + P
Sbjct: 153 RTLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPP 189
Score = 55.2 bits (127), Expect = 3e-07
Identities = 24/90 (26%), Positives = 50/90 (55%)
Frame = +2
Query: 482 LTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRL 661
L + N+L +P+++ L L+ L +E NQ+ LP ++ +T L N+++N+L
Sbjct: 80 LATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKL 139
Query: 662 EQFPSSILKCKELMFLQLNSNQISSVPANL 751
++ P ++ + + L L ++ N+I +P L
Sbjct: 140 KELPDTVGELRSLRTLNISGNEIQRLPQML 169
Score = 50.4 bits (115), Expect = 8e-06
Identities = 24/67 (35%), Positives = 39/67 (58%)
Frame = +2
Query: 542 MTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNS 721
+ SLA ++ L L +NQ+ LPD + ++TAL N+ N+L Q P SI +L L +
Sbjct: 77 LLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKD 136
Query: 722 NQISSVP 742
N++ +P
Sbjct: 137 NKLKELP 143
>AL445222-17|CAH72931.1| 696|Homo sapiens leucine rich repeat and
sterile alpha motif containing 1 protein.
Length = 696
Score = 62.9 bits (146), Expect = 1e-09
Identities = 36/124 (29%), Positives = 59/124 (47%)
Frame = +2
Query: 341 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 520
+L + L+L N L L ++G L L+ R L ++P+ IG LTQL T + N+
Sbjct: 79 SLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNK 138
Query: 521 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 700
LK +P+ + L LR L + N+I+ LP + + L +L + + P +
Sbjct: 139 LKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPPREVCGAGTA 198
Query: 701 MFLQ 712
LQ
Sbjct: 199 AILQ 202
Score = 58.0 bits (134), Expect = 4e-08
Identities = 48/183 (26%), Positives = 82/183 (44%), Gaps = 8/183 (4%)
Frame = +2
Query: 155 LSLNGFEITEIP-GLLYTC--LEVEHLYLHKNKI-SIFP--VEXXXXXXXXXXXXXXXXX 316
L ++ E++EIP G TC L+ + L +H N + S+ P
Sbjct: 34 LDISKCELSEIPFGAFATCKVLQKKVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQL 93
Query: 317 XXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLD 496
P ++G L L LN+ N L L IG+L +L+ LKE+P +G+L L
Sbjct: 94 TALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSLR 153
Query: 497 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM--DRMTALVHCNLRNNRLEQF 670
T GNE++ +P+ + + L L+L+ + + P + A++ + + LE +
Sbjct: 154 TLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPPREVCGAGTAAILQFLCKESGLEYY 213
Query: 671 PSS 679
P S
Sbjct: 214 PPS 216
Score = 58.0 bits (134), Expect = 4e-08
Identities = 25/97 (25%), Positives = 54/97 (55%)
Frame = +2
Query: 452 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 631
L +P ++G+LT L N+L +P + +L +L+ L +++N+++ LPDT+ + +L
Sbjct: 93 LTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSL 152
Query: 632 VHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVP 742
N+ N +++ P + + L L L+++ + P
Sbjct: 153 RTLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPP 189
Score = 55.2 bits (127), Expect = 3e-07
Identities = 24/90 (26%), Positives = 50/90 (55%)
Frame = +2
Query: 482 LTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRL 661
L + N+L +P+++ L L+ L +E NQ+ LP ++ +T L N+++N+L
Sbjct: 80 LATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKL 139
Query: 662 EQFPSSILKCKELMFLQLNSNQISSVPANL 751
++ P ++ + + L L ++ N+I +P L
Sbjct: 140 KELPDTVGELRSLRTLNISGNEIQRLPQML 169
Score = 50.4 bits (115), Expect = 8e-06
Identities = 24/67 (35%), Positives = 39/67 (58%)
Frame = +2
Query: 542 MTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNS 721
+ SLA ++ L L +NQ+ LPD + ++TAL N+ N+L Q P SI +L L +
Sbjct: 77 LLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKD 136
Query: 722 NQISSVP 742
N++ +P
Sbjct: 137 NKLKELP 143
>AL445222-16|CAH72930.1| 723|Homo sapiens leucine rich repeat and
sterile alpha motif containing 1 protein.
Length = 723
Score = 62.9 bits (146), Expect = 1e-09
Identities = 36/124 (29%), Positives = 59/124 (47%)
Frame = +2
Query: 341 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 520
+L + L+L N L L ++G L L+ R L ++P+ IG LTQL T + N+
Sbjct: 79 SLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNK 138
Query: 521 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 700
LK +P+ + L LR L + N+I+ LP + + L +L + + P +
Sbjct: 139 LKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPPREVCGAGTA 198
Query: 701 MFLQ 712
LQ
Sbjct: 199 AILQ 202
Score = 58.0 bits (134), Expect = 4e-08
Identities = 48/183 (26%), Positives = 82/183 (44%), Gaps = 8/183 (4%)
Frame = +2
Query: 155 LSLNGFEITEIP-GLLYTC--LEVEHLYLHKNKI-SIFP--VEXXXXXXXXXXXXXXXXX 316
L ++ E++EIP G TC L+ + L +H N + S+ P
Sbjct: 34 LDISKCELSEIPFGAFATCKVLQKKVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQL 93
Query: 317 XXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLD 496
P ++G L L LN+ N L L IG+L +L+ LKE+P +G+L L
Sbjct: 94 TALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSLR 153
Query: 497 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM--DRMTALVHCNLRNNRLEQF 670
T GNE++ +P+ + + L L+L+ + + P + A++ + + LE +
Sbjct: 154 TLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPPREVCGAGTAAILQFLCKESGLEYY 213
Query: 671 PSS 679
P S
Sbjct: 214 PPS 216
Score = 58.0 bits (134), Expect = 4e-08
Identities = 25/97 (25%), Positives = 54/97 (55%)
Frame = +2
Query: 452 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 631
L +P ++G+LT L N+L +P + +L +L+ L +++N+++ LPDT+ + +L
Sbjct: 93 LTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSL 152
Query: 632 VHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVP 742
N+ N +++ P + + L L L+++ + P
Sbjct: 153 RTLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPP 189
Score = 55.2 bits (127), Expect = 3e-07
Identities = 24/90 (26%), Positives = 50/90 (55%)
Frame = +2
Query: 482 LTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRL 661
L + N+L +P+++ L L+ L +E NQ+ LP ++ +T L N+++N+L
Sbjct: 80 LATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKL 139
Query: 662 EQFPSSILKCKELMFLQLNSNQISSVPANL 751
++ P ++ + + L L ++ N+I +P L
Sbjct: 140 KELPDTVGELRSLRTLNISGNEIQRLPQML 169
Score = 50.4 bits (115), Expect = 8e-06
Identities = 24/67 (35%), Positives = 39/67 (58%)
Frame = +2
Query: 542 MTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNS 721
+ SLA ++ L L +NQ+ LPD + ++TAL N+ N+L Q P SI +L L +
Sbjct: 77 LLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKD 136
Query: 722 NQISSVP 742
N++ +P
Sbjct: 137 NKLKELP 143
>AL365215-2|CAH73632.1| 224|Homo sapiens Ras suppressor protein 1
protein.
Length = 224
Score = 62.9 bits (146), Expect = 1e-09
Identities = 37/121 (30%), Positives = 59/121 (48%), Gaps = 2/121 (1%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAF--WCNRIGLKEIPKEIGKLTQLDT 499
PT+I +L+ L +LNL N LN L G L LE N + +P LT L
Sbjct: 26 PTQISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRA 85
Query: 500 FGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSS 679
N+ + +P ++ L KL+ L+L +N + +LP + +T L +++ NRL P
Sbjct: 86 LYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPE 145
Query: 680 I 682
+
Sbjct: 146 L 146
Score = 56.0 bits (129), Expect = 2e-07
Identities = 38/129 (29%), Positives = 57/129 (44%), Gaps = 2/129 (1%)
Frame = +2
Query: 173 EITEIPGLLYTCLEVEHLYLHKNKISIFP--VEXXXXXXXXXXXXXXXXXXXXPTEIGNL 346
+I E+P + + +++HL L N+++ P P L
Sbjct: 21 QIEELPTQISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYL 80
Query: 347 KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELK 526
L L LS N +L P+IG L KL+ L +PKEIG+LTQL +GN L
Sbjct: 81 TTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLT 140
Query: 527 TIPEEMTSL 553
+P E+ +L
Sbjct: 141 VLPPELGNL 149
Score = 55.6 bits (128), Expect = 2e-07
Identities = 38/148 (25%), Positives = 65/148 (43%), Gaps = 2/148 (1%)
Frame = +2
Query: 185 IPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNL 364
+P + +E L N+I P + P G+L L L
Sbjct: 2 VPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVL 61
Query: 365 NLSYNPL--NVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE 538
+L+YN L N L L L A + + + +P +IGKLT+L R N+L ++P+
Sbjct: 62 DLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPK 121
Query: 539 EMTSLAKLRWLTLENNQIETLPDTMDRM 622
E+ L +L+ L ++ N++ LP + +
Sbjct: 122 EIGELTQLKELHIQGNRLTVLPPELGNL 149
Score = 44.8 bits (101), Expect = 4e-04
Identities = 27/75 (36%), Positives = 33/75 (44%), Gaps = 2/75 (2%)
Frame = +2
Query: 530 IPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFL 709
+P + L L L NNQIE LP + + L H NL NRL P L L
Sbjct: 2 VPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVL 61
Query: 710 QLNSNQIS--SVPAN 748
L N +S S+P N
Sbjct: 62 DLTYNNLSENSLPGN 76
Score = 43.6 bits (98), Expect = 9e-04
Identities = 25/88 (28%), Positives = 35/88 (39%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L+ N +PG + + LYL N I P + P E
Sbjct: 63 LTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKE 122
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLE 418
IG L L L++ N L VL PE+G+L+
Sbjct: 123 IGELTQLKELHIQGNRLTVLPPELGNLD 150
>AK091589-1|BAC03703.1| 723|Homo sapiens protein ( Homo sapiens
cDNA FLJ34270 fis, clone FEBRA2003100. ).
Length = 723
Score = 62.9 bits (146), Expect = 1e-09
Identities = 36/124 (29%), Positives = 59/124 (47%)
Frame = +2
Query: 341 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 520
+L + L+L N L L ++G L L+ R L ++P+ IG LTQL T + N+
Sbjct: 79 SLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNK 138
Query: 521 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 700
LK +P+ + L LR L + N+I+ LP + + L +L + + P +
Sbjct: 139 LKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPPREVCGAGTA 198
Query: 701 MFLQ 712
LQ
Sbjct: 199 AILQ 202
Score = 58.0 bits (134), Expect = 4e-08
Identities = 48/183 (26%), Positives = 82/183 (44%), Gaps = 8/183 (4%)
Frame = +2
Query: 155 LSLNGFEITEIP-GLLYTC--LEVEHLYLHKNKI-SIFP--VEXXXXXXXXXXXXXXXXX 316
L ++ E++EIP G TC L+ + L +H N + S+ P
Sbjct: 34 LDISKCELSEIPFGAFATCKVLQKKVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQL 93
Query: 317 XXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLD 496
P ++G L L LN+ N L L IG+L +L+ LKE+P +G+L L
Sbjct: 94 TALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSLR 153
Query: 497 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM--DRMTALVHCNLRNNRLEQF 670
T GNE++ +P+ + + L L+L+ + + P + A++ + + LE +
Sbjct: 154 TLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPPREVCGAGTAAILQFLCKESGLEYY 213
Query: 671 PSS 679
P S
Sbjct: 214 PPS 216
Score = 58.0 bits (134), Expect = 4e-08
Identities = 25/97 (25%), Positives = 54/97 (55%)
Frame = +2
Query: 452 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 631
L +P ++G+LT L N+L +P + +L +L+ L +++N+++ LPDT+ + +L
Sbjct: 93 LTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSL 152
Query: 632 VHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVP 742
N+ N +++ P + + L L L+++ + P
Sbjct: 153 RTLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPP 189
Score = 55.2 bits (127), Expect = 3e-07
Identities = 24/90 (26%), Positives = 50/90 (55%)
Frame = +2
Query: 482 LTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRL 661
L + N+L +P+++ L L+ L +E NQ+ LP ++ +T L N+++N+L
Sbjct: 80 LATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKL 139
Query: 662 EQFPSSILKCKELMFLQLNSNQISSVPANL 751
++ P ++ + + L L ++ N+I +P L
Sbjct: 140 KELPDTVGELRSLRTLNISGNEIQRLPQML 169
Score = 50.4 bits (115), Expect = 8e-06
Identities = 24/67 (35%), Positives = 39/67 (58%)
Frame = +2
Query: 542 MTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNS 721
+ SLA ++ L L +NQ+ LPD + ++TAL N+ N+L Q P SI +L L +
Sbjct: 77 LLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKD 136
Query: 722 NQISSVP 742
N++ +P
Sbjct: 137 NKLKELP 143
>AK056203-1|BAB71119.1| 696|Homo sapiens protein ( Homo sapiens
cDNA FLJ31641 fis, clone NT2RI2003695, weakly similar to
TRICHOHYALIN. ).
Length = 696
Score = 62.9 bits (146), Expect = 1e-09
Identities = 36/124 (29%), Positives = 59/124 (47%)
Frame = +2
Query: 341 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 520
+L + L+L N L L ++G L L+ R L ++P+ IG LTQL T + N+
Sbjct: 79 SLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNK 138
Query: 521 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 700
LK +P+ + L LR L + N+I+ LP + + L +L + + P +
Sbjct: 139 LKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPPREVCGAGTA 198
Query: 701 MFLQ 712
LQ
Sbjct: 199 AILQ 202
Score = 58.0 bits (134), Expect = 4e-08
Identities = 48/183 (26%), Positives = 82/183 (44%), Gaps = 8/183 (4%)
Frame = +2
Query: 155 LSLNGFEITEIP-GLLYTC--LEVEHLYLHKNKI-SIFP--VEXXXXXXXXXXXXXXXXX 316
L ++ E++EIP G TC L+ + L +H N + S+ P
Sbjct: 34 LDISKCELSEIPFGAFATCKVLQKKVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQL 93
Query: 317 XXXPTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLD 496
P ++G L L LN+ N L L IG+L +L+ LKE+P +G+L L
Sbjct: 94 TALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSLR 153
Query: 497 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM--DRMTALVHCNLRNNRLEQF 670
T GNE++ +P+ + + L L+L+ + + P + A++ + + LE +
Sbjct: 154 TLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPPREVCGAGTAAILQFLCKESGLEYY 213
Query: 671 PSS 679
P S
Sbjct: 214 PPS 216
Score = 58.0 bits (134), Expect = 4e-08
Identities = 25/97 (25%), Positives = 54/97 (55%)
Frame = +2
Query: 452 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 631
L +P ++G+LT L N+L +P + +L +L+ L +++N+++ LPDT+ + +L
Sbjct: 93 LTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSL 152
Query: 632 VHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVP 742
N+ N +++ P + + L L L+++ + P
Sbjct: 153 RTLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPP 189
Score = 55.2 bits (127), Expect = 3e-07
Identities = 24/90 (26%), Positives = 50/90 (55%)
Frame = +2
Query: 482 LTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRL 661
L + N+L +P+++ L L+ L +E NQ+ LP ++ +T L N+++N+L
Sbjct: 80 LATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKL 139
Query: 662 EQFPSSILKCKELMFLQLNSNQISSVPANL 751
++ P ++ + + L L ++ N+I +P L
Sbjct: 140 KELPDTVGELRSLRTLNISGNEIQRLPQML 169
Score = 50.4 bits (115), Expect = 8e-06
Identities = 24/67 (35%), Positives = 39/67 (58%)
Frame = +2
Query: 542 MTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNS 721
+ SLA ++ L L +NQ+ LPD + ++TAL N+ N+L Q P SI +L L +
Sbjct: 77 LLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKD 136
Query: 722 NQISSVP 742
N++ +P
Sbjct: 137 NKLKELP 143
>AL589786-1|CAH70721.1| 612|Homo sapiens leucine-rich repeats and
calponin homology (CH) domain containing 2 protein.
Length = 612
Score = 62.5 bits (145), Expect = 2e-09
Identities = 41/133 (30%), Positives = 65/133 (48%)
Frame = +2
Query: 353 LVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI 532
L LN+S N L+ L + DL L+ + L IP+EIGKL L NE++ +
Sbjct: 2 LTYLNISRNLLSTLPKYLFDLP-LKVLVVSNNKLVSIPEEIGKLKDLMELDISCNEIQVL 60
Query: 533 PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQ 712
P++M L LR L + N + LPD + + LV + N++ + P K L +
Sbjct: 61 PQQMGKLHSLRELNIRRNNLHVLPDELGDL-PLVKLDFSCNKVTEIPVCYRKLHHLQVII 119
Query: 713 LNSNQISSVPANL 751
L++N + PA +
Sbjct: 120 LDNNPLQVPPAQI 132
Score = 44.8 bits (101), Expect = 4e-04
Identities = 40/152 (26%), Positives = 66/152 (43%), Gaps = 5/152 (3%)
Frame = +2
Query: 176 ITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 355
++ +P L+ L ++ L + NK+ P E P ++G L +L
Sbjct: 12 LSTLPKYLFD-LPLKVLVVSNNKLVSIPEEIGKLKDLMELDISCNEIQVLPQQMGKLHSL 70
Query: 356 VNLNLSYNPLNVLIPEIGDLEKLEA-FWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI 532
LN+ N L+VL E+GDL ++ F CN++ EIP KL L N L+
Sbjct: 71 RELNIRRNNLHVLPDELGDLPLVKLDFSCNKV--TEIPVCYRKLHHLQVIILDNNPLQVP 128
Query: 533 PEEMTSLAKLRWLTLENNQ----IETLPDTMD 616
P ++ K+ N Q ++ PD++D
Sbjct: 129 PAQICLKGKVHIFKYLNIQACCRMDKKPDSLD 160
>AL445164-1|CAI43033.1| 612|Homo sapiens leucine-rich repeats and
calponin homology (CH) domain containing 2 protein.
Length = 612
Score = 62.5 bits (145), Expect = 2e-09
Identities = 41/133 (30%), Positives = 65/133 (48%)
Frame = +2
Query: 353 LVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI 532
L LN+S N L+ L + DL L+ + L IP+EIGKL L NE++ +
Sbjct: 2 LTYLNISRNLLSTLPKYLFDLP-LKVLVVSNNKLVSIPEEIGKLKDLMELDISCNEIQVL 60
Query: 533 PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQ 712
P++M L LR L + N + LPD + + LV + N++ + P K L +
Sbjct: 61 PQQMGKLHSLRELNIRRNNLHVLPDELGDL-PLVKLDFSCNKVTEIPVCYRKLHHLQVII 119
Query: 713 LNSNQISSVPANL 751
L++N + PA +
Sbjct: 120 LDNNPLQVPPAQI 132
Score = 44.8 bits (101), Expect = 4e-04
Identities = 40/152 (26%), Positives = 66/152 (43%), Gaps = 5/152 (3%)
Frame = +2
Query: 176 ITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 355
++ +P L+ L ++ L + NK+ P E P ++G L +L
Sbjct: 12 LSTLPKYLFD-LPLKVLVVSNNKLVSIPEEIGKLKDLMELDISCNEIQVLPQQMGKLHSL 70
Query: 356 VNLNLSYNPLNVLIPEIGDLEKLEA-FWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI 532
LN+ N L+VL E+GDL ++ F CN++ EIP KL L N L+
Sbjct: 71 RELNIRRNNLHVLPDELGDLPLVKLDFSCNKV--TEIPVCYRKLHHLQVIILDNNPLQVP 128
Query: 533 PEEMTSLAKLRWLTLENNQ----IETLPDTMD 616
P ++ K+ N Q ++ PD++D
Sbjct: 129 PAQICLKGKVHIFKYLNIQACCRMDKKPDSLD 160
>AL121878-2|CAI42077.1| 612|Homo sapiens leucine-rich repeats and
calponin homology (CH) domain containing 2 protein.
Length = 612
Score = 62.5 bits (145), Expect = 2e-09
Identities = 41/133 (30%), Positives = 65/133 (48%)
Frame = +2
Query: 353 LVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI 532
L LN+S N L+ L + DL L+ + L IP+EIGKL L NE++ +
Sbjct: 2 LTYLNISRNLLSTLPKYLFDLP-LKVLVVSNNKLVSIPEEIGKLKDLMELDISCNEIQVL 60
Query: 533 PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQ 712
P++M L LR L + N + LPD + + LV + N++ + P K L +
Sbjct: 61 PQQMGKLHSLRELNIRRNNLHVLPDELGDL-PLVKLDFSCNKVTEIPVCYRKLHHLQVII 119
Query: 713 LNSNQISSVPANL 751
L++N + PA +
Sbjct: 120 LDNNPLQVPPAQI 132
Score = 44.8 bits (101), Expect = 4e-04
Identities = 40/152 (26%), Positives = 66/152 (43%), Gaps = 5/152 (3%)
Frame = +2
Query: 176 ITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 355
++ +P L+ L ++ L + NK+ P E P ++G L +L
Sbjct: 12 LSTLPKYLFD-LPLKVLVVSNNKLVSIPEEIGKLKDLMELDISCNEIQVLPQQMGKLHSL 70
Query: 356 VNLNLSYNPLNVLIPEIGDLEKLEA-FWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI 532
LN+ N L+VL E+GDL ++ F CN++ EIP KL L N L+
Sbjct: 71 RELNIRRNNLHVLPDELGDLPLVKLDFSCNKV--TEIPVCYRKLHHLQVIILDNNPLQVP 128
Query: 533 PEEMTSLAKLRWLTLENNQ----IETLPDTMD 616
P ++ K+ N Q ++ PD++D
Sbjct: 129 PAQICLKGKVHIFKYLNIQACCRMDKKPDSLD 160
>D86984-1|BAA13220.2| 823|Homo sapiens KIAA0231 protein protein.
Length = 823
Score = 62.1 bits (144), Expect = 2e-09
Identities = 39/138 (28%), Positives = 66/138 (47%)
Frame = +2
Query: 341 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 520
+L+NL L L +N + + +IG L LE + ++ +P ++ T+L N
Sbjct: 651 HLQNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNH 710
Query: 521 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 700
L IPEE+ L+ L++ + NN IE LPD + + L L N L + + L
Sbjct: 711 LTFIPEEIQYLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMNLSPHVGELSNL 770
Query: 701 MFLQLNSNQISSVPANLD 754
L+L N + ++P L+
Sbjct: 771 THLELIGNYLETLPPELE 788
>BC060782-1|AAH60782.1| 803|Homo sapiens LRRC8B protein protein.
Length = 803
Score = 62.1 bits (144), Expect = 2e-09
Identities = 39/138 (28%), Positives = 66/138 (47%)
Frame = +2
Query: 341 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 520
+L+NL L L +N + + +IG L LE + ++ +P ++ T+L N
Sbjct: 631 HLQNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNH 690
Query: 521 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 700
L IPEE+ L+ L++ + NN IE LPD + + L L N L + + L
Sbjct: 691 LTFIPEEIQYLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMNLSPHVGELSNL 750
Query: 701 MFLQLNSNQISSVPANLD 754
L+L N + ++P L+
Sbjct: 751 THLELIGNYLETLPPELE 768
>BC030607-1|AAH30607.1| 803|Homo sapiens leucine rich repeat
containing 8 family, member B protein.
Length = 803
Score = 62.1 bits (144), Expect = 2e-09
Identities = 39/138 (28%), Positives = 66/138 (47%)
Frame = +2
Query: 341 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 520
+L+NL L L +N + + +IG L LE + ++ +P ++ T+L N
Sbjct: 631 HLQNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNH 690
Query: 521 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 700
L IPEE+ L+ L++ + NN IE LPD + + L L N L + + L
Sbjct: 691 LTFIPEEIQYLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMNLSPHVGELSNL 750
Query: 701 MFLQLNSNQISSVPANLD 754
L+L N + ++P L+
Sbjct: 751 THLELIGNYLETLPPELE 768
>AY358112-1|AAQ88479.1| 802|Homo sapiens ITLT6413 protein.
Length = 802
Score = 62.1 bits (144), Expect = 2e-09
Identities = 39/138 (28%), Positives = 66/138 (47%)
Frame = +2
Query: 341 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 520
+L+NL L L +N + + +IG L LE + ++ +P ++ T+L N
Sbjct: 630 HLQNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNH 689
Query: 521 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 700
L IPEE+ L+ L++ + NN IE LPD + + L L N L + + L
Sbjct: 690 LTFIPEEIQYLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMNLSPHVGELSNL 749
Query: 701 MFLQLNSNQISSVPANLD 754
L+L N + ++P L+
Sbjct: 750 THLELIGNYLETLPPELE 767
>AF385436-1|AAM43837.1| 803|Homo sapiens T-cell activation leucine
repeat-rich protein protein.
Length = 803
Score = 62.1 bits (144), Expect = 2e-09
Identities = 39/138 (28%), Positives = 66/138 (47%)
Frame = +2
Query: 341 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 520
+L+NL L L +N + + +IG L LE + ++ +P ++ T+L N
Sbjct: 631 HLQNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNH 690
Query: 521 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 700
L IPEE+ L+ L++ + NN IE LPD + + L L N L + + L
Sbjct: 691 LTFIPEEIQYLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMNLSPHVGELSNL 750
Query: 701 MFLQLNSNQISSVPANLD 754
L+L N + ++P L+
Sbjct: 751 THLELIGNYLETLPPELE 768
>BC099650-1|AAH99650.1| 907|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 5 protein.
Length = 907
Score = 61.3 bits (142), Expect = 4e-09
Identities = 51/165 (30%), Positives = 78/165 (47%), Gaps = 5/165 (3%)
Frame = +2
Query: 326 PTE-IGNLKNLVNLNLSYNPLNVLIPE-IGDLEKLEAFWCNRIGLKEIPKEIGK-LTQLD 496
PTE + NL++L +L L N ++ + P L L W + L EIP + + L+ L
Sbjct: 130 PTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQ 189
Query: 497 TFGARGNELKTIPE-EMTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQF 670
N++ IP+ +L+ L L L NN+I +L D + +L +L N L++F
Sbjct: 190 AMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEF 249
Query: 671 PSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
P++I L L +SN I S+P P L I NPI
Sbjct: 250 PTAIRTLSNLKELGFHSNNIRSIPEKAFVG-NPSLITIHFYDNPI 293
Score = 42.7 bits (96), Expect = 0.002
Identities = 50/171 (29%), Positives = 75/171 (43%), Gaps = 5/171 (2%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPE---IGDLEKLEA-FWCNRIGLKEIPKEIGKLTQL 493
PT I L NL L N + IPE +G+ + F+ N I L +L
Sbjct: 250 PTAIRTLSNLKELGFHSNNIRS-IPEKAFVGNPSLITIHFYDNPIQFVG-RSAFQHLPEL 307
Query: 494 DTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM-DRMTALVHCNLRNNRLEQF 670
T G T ++T A L LTL QI +LP T+ +++ L +L N LE
Sbjct: 308 RTLTLNGASQITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDL 367
Query: 671 PSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELSHP 823
PS + C++L + L N+I + + L+ L ++L N I + HP
Sbjct: 368 PSFSV-CQKLQKIDLRHNEIYEIKVDTFQQLL-SLRSLNLAWNKIA-IIHP 415
Score = 41.1 bits (92), Expect = 0.005
Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 3/104 (2%)
Frame = +2
Query: 461 IPKEIGKLTQLDTFGARGNELKTIPE-EMTSLAKLRWLTLENNQIETLP-DTMDRMTALV 634
+P + L L+ GN L IP+ T L L+ L L+NNQ+ +P + + + +L
Sbjct: 82 LPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQ 141
Query: 635 HCNLRNNRLEQFPSSILK-CKELMFLQLNSNQISSVPANLDTSL 763
L N + P S L L L+ N ++ +P SL
Sbjct: 142 SLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSL 185
Score = 40.3 bits (90), Expect = 0.008
Identities = 45/201 (22%), Positives = 78/201 (38%), Gaps = 5/201 (2%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXX--XXXXXXXXXXXXXXXXP 328
L LN + E P + T ++ L H N I P +
Sbjct: 239 LDLNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGR 298
Query: 329 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEI-GKLTQLDTFG 505
+ +L L L L+ P++ LE+ + +P+ + +L L
Sbjct: 299 SAFQHLPELRTLTLNGASQITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLD 358
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQI-ETLPDTMDRMTALVHCNLRNNRLEQF-PSS 679
N L+ +P + KL+ + L +N+I E DT ++ +L NL N++ P++
Sbjct: 359 LSYNLLEDLP-SFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNA 417
Query: 680 ILKCKELMFLQLNSNQISSVP 742
L+ L L+SN +SS P
Sbjct: 418 FSTLPSLIKLDLSSNLLSSFP 438
>BC096324-1|AAH96324.1| 907|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 5 protein.
Length = 907
Score = 61.3 bits (142), Expect = 4e-09
Identities = 51/165 (30%), Positives = 78/165 (47%), Gaps = 5/165 (3%)
Frame = +2
Query: 326 PTE-IGNLKNLVNLNLSYNPLNVLIPE-IGDLEKLEAFWCNRIGLKEIPKEIGK-LTQLD 496
PTE + NL++L +L L N ++ + P L L W + L EIP + + L+ L
Sbjct: 130 PTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQ 189
Query: 497 TFGARGNELKTIPE-EMTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQF 670
N++ IP+ +L+ L L L NN+I +L D + +L +L N L++F
Sbjct: 190 AMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEF 249
Query: 671 PSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
P++I L L +SN I S+P P L I NPI
Sbjct: 250 PTAIRTLSNLKELGFHSNNIRSIPEKAFVG-NPSLITIHFYDNPI 293
Score = 42.7 bits (96), Expect = 0.002
Identities = 50/171 (29%), Positives = 75/171 (43%), Gaps = 5/171 (2%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPE---IGDLEKLEA-FWCNRIGLKEIPKEIGKLTQL 493
PT I L NL L N + IPE +G+ + F+ N I L +L
Sbjct: 250 PTAIRTLSNLKELGFHSNNIRS-IPEKAFVGNPSLITIHFYDNPIQFVG-RSAFQHLPEL 307
Query: 494 DTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM-DRMTALVHCNLRNNRLEQF 670
T G T ++T A L LTL QI +LP T+ +++ L +L N LE
Sbjct: 308 RTLTLNGASQITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDL 367
Query: 671 PSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELSHP 823
PS + C++L + L N+I + + L+ L ++L N I + HP
Sbjct: 368 PSFSV-CQKLQKIDLRHNEIYEIKVDTFQQLL-SLRSLNLAWNKIA-IIHP 415
Score = 41.1 bits (92), Expect = 0.005
Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 3/104 (2%)
Frame = +2
Query: 461 IPKEIGKLTQLDTFGARGNELKTIPE-EMTSLAKLRWLTLENNQIETLP-DTMDRMTALV 634
+P + L L+ GN L IP+ T L L+ L L+NNQ+ +P + + + +L
Sbjct: 82 LPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQ 141
Query: 635 HCNLRNNRLEQFPSSILK-CKELMFLQLNSNQISSVPANLDTSL 763
L N + P S L L L+ N ++ +P SL
Sbjct: 142 SLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSL 185
Score = 40.3 bits (90), Expect = 0.008
Identities = 45/201 (22%), Positives = 78/201 (38%), Gaps = 5/201 (2%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXX--XXXXXXXXXXXXXXXXP 328
L LN + E P + T ++ L H N I P +
Sbjct: 239 LDLNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGR 298
Query: 329 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEI-GKLTQLDTFG 505
+ +L L L L+ P++ LE+ + +P+ + +L L
Sbjct: 299 SAFQHLPELRTLTLNGASQITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLD 358
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQI-ETLPDTMDRMTALVHCNLRNNRLEQF-PSS 679
N L+ +P + KL+ + L +N+I E DT ++ +L NL N++ P++
Sbjct: 359 LSYNLLEDLP-SFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNA 417
Query: 680 ILKCKELMFLQLNSNQISSVP 742
L+ L L+SN +SS P
Sbjct: 418 FSTLPSLIKLDLSSNLLSSFP 438
>AF062006-1|AAC28019.1| 907|Homo sapiens orphan G protein-coupled
receptor HG38 protein.
Length = 907
Score = 61.3 bits (142), Expect = 4e-09
Identities = 51/165 (30%), Positives = 78/165 (47%), Gaps = 5/165 (3%)
Frame = +2
Query: 326 PTE-IGNLKNLVNLNLSYNPLNVLIPE-IGDLEKLEAFWCNRIGLKEIPKEIGK-LTQLD 496
PTE + NL++L +L L N ++ + P L L W + L EIP + + L+ L
Sbjct: 130 PTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQ 189
Query: 497 TFGARGNELKTIPE-EMTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQF 670
N++ IP+ +L+ L L L NN+I +L D + +L +L N L++F
Sbjct: 190 AMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEF 249
Query: 671 PSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
P++I L L +SN I S+P P L I NPI
Sbjct: 250 PTAIRTLSNLKELGFHSNNIRSIPEKAFVG-NPSLITIHFYDNPI 293
Score = 42.7 bits (96), Expect = 0.002
Identities = 50/171 (29%), Positives = 75/171 (43%), Gaps = 5/171 (2%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPE---IGDLEKLEA-FWCNRIGLKEIPKEIGKLTQL 493
PT I L NL L N + IPE +G+ + F+ N I L +L
Sbjct: 250 PTAIRTLSNLKELGFHSNNIRS-IPEKAFVGNPSLITIHFYDNPIQFVG-RSAFQHLPEL 307
Query: 494 DTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM-DRMTALVHCNLRNNRLEQF 670
T G T ++T A L LTL QI +LP T+ +++ L +L N LE
Sbjct: 308 RTLTLNGASQITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDL 367
Query: 671 PSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELSHP 823
PS + C++L + L N+I + + L+ L ++L N I + HP
Sbjct: 368 PSFSV-CQKLQKIDLRHNEIYEIKVDTFQQLL-SLRSLNLAWNKIA-IIHP 415
Score = 41.1 bits (92), Expect = 0.005
Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 3/104 (2%)
Frame = +2
Query: 461 IPKEIGKLTQLDTFGARGNELKTIPE-EMTSLAKLRWLTLENNQIETLP-DTMDRMTALV 634
+P + L L+ GN L IP+ T L L+ L L+NNQ+ +P + + + +L
Sbjct: 82 LPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQ 141
Query: 635 HCNLRNNRLEQFPSSILK-CKELMFLQLNSNQISSVPANLDTSL 763
L N + P S L L L+ N ++ +P SL
Sbjct: 142 SLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSL 185
Score = 40.3 bits (90), Expect = 0.008
Identities = 45/201 (22%), Positives = 78/201 (38%), Gaps = 5/201 (2%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXX--XXXXXXXXXXXXXXXXP 328
L LN + E P + T ++ L H N I P +
Sbjct: 239 LDLNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGR 298
Query: 329 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEI-GKLTQLDTFG 505
+ +L L L L+ P++ LE+ + +P+ + +L L
Sbjct: 299 SAFQHLPELRTLTLNGASQITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLD 358
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQI-ETLPDTMDRMTALVHCNLRNNRLEQF-PSS 679
N L+ +P + KL+ + L +N+I E DT ++ +L NL N++ P++
Sbjct: 359 LSYNLLEDLP-SFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNA 417
Query: 680 ILKCKELMFLQLNSNQISSVP 742
L+ L L+SN +SS P
Sbjct: 418 FSTLPSLIKLDLSSNLLSSFP 438
>BC007504-1|AAH07504.1| 712|Homo sapiens leucine-rich repeats and
calponin homology (CH) domain containing 3 protein.
Length = 712
Score = 60.5 bits (140), Expect = 7e-09
Identities = 46/160 (28%), Positives = 77/160 (48%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P E + +L NLNL N + + I +L+ L +R L +P + L L
Sbjct: 98 PIEACHFVSLENLNLYQNCIRYIPEAILNLQALTFLNISRNQLSTLPVHLCNLP-LKVLI 156
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
A N+L ++PEE+ L L L + N+I+T+P + + AL N+R N L P +
Sbjct: 157 ASNNKLVSLPEEIGHLRHLMELDVSCNEIQTIPSQIGNLEALRDLNVRRNHLVHLPEELA 216
Query: 686 KCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
+ L+ L + N+I+++P + L I L +NP+
Sbjct: 217 EL-PLIRLDFSCNKITTIPVCYRN--LRHLQTITLDNNPL 253
Score = 56.0 bits (129), Expect = 2e-07
Identities = 39/143 (27%), Positives = 68/143 (47%)
Frame = +2
Query: 176 ITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNL 355
I IP + + L + +N++S PV P EIG+L++L
Sbjct: 117 IRYIPEAILNLQALTFLNISRNQLSTLPVHLCNLPLKVLIASNNKLVSL-PEEIGHLRHL 175
Query: 356 VNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 535
+ L++S N + + +IG+LE L R L +P+E+ +L L N++ TIP
Sbjct: 176 MELDVSCNEIQTIPSQIGNLEALRDLNVRRNHLVHLPEELAELP-LIRLDFSCNKITTIP 234
Query: 536 EEMTSLAKLRWLTLENNQIETLP 604
+L L+ +TL+NN +++ P
Sbjct: 235 VCYRNLRHLQTITLDNNPLQSPP 257
Score = 53.2 bits (122), Expect = 1e-06
Identities = 35/125 (28%), Positives = 60/125 (48%)
Frame = +2
Query: 440 NRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDR 619
+R L EIP E L+ N ++ IPE + +L L +L + NQ+ TLP +
Sbjct: 90 SRNRLSEIPIEACHFVSLENLNLYQNCIRYIPEAILNLQALTFLNISRNQLSTLPVHLCN 149
Query: 620 MTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSN 799
+ V NN+L P I + LM L ++ N+I ++P+ + + L +++R N
Sbjct: 150 LPLKV-LIASNNKLVSLPEEIGHLRHLMELDVSCNEIQTIPSQIGN--LEALRDLNVRRN 206
Query: 800 PICEL 814
+ L
Sbjct: 207 HLVHL 211
Score = 47.2 bits (107), Expect = 7e-05
Identities = 34/137 (24%), Positives = 63/137 (45%)
Frame = +2
Query: 341 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 520
+L + +LS N L+ + E LE + ++ IP+ I L L N+
Sbjct: 80 DLTDTTRADLSRNRLSEIPIEACHFVSLENLNLYQNCIRYIPEAILNLQALTFLNISRNQ 139
Query: 521 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 700
L T+P + +L L+ L NN++ +LP+ + + L+ ++ N ++ PS I + L
Sbjct: 140 LSTLPVHLCNL-PLKVLIASNNKLVSLPEEIGHLRHLMELDVSCNEIQTIPSQIGNLEAL 198
Query: 701 MFLQLNSNQISSVPANL 751
L + N + +P L
Sbjct: 199 RDLNVRRNHLVHLPEEL 215
>AK124678-1|BAC85924.1| 423|Homo sapiens protein ( Homo sapiens
cDNA FLJ42687 fis, clone BRAMY3001794, moderately
similar to Rattus norvegicus SCN circadian oscillatory
protein (Scop). ).
Length = 423
Score = 59.7 bits (138), Expect = 1e-08
Identities = 39/114 (34%), Positives = 58/114 (50%), Gaps = 3/114 (2%)
Frame = +2
Query: 353 LVNLNLSYNPLN---VLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNEL 523
L LNLS+N L +L+ EI L +L CN G ++P +IG L L T GN L
Sbjct: 301 LKGLNLSHNKLGLFPILLCEISTLTELNLS-CN--GFHDLPSQIGNLLNLQTLCLDGNFL 357
Query: 524 KTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
T+PEE+ +L +L L + N +P+ +++T L + N LE +L
Sbjct: 358 TTLPEELGNLQQLSSLGISFNNFSQIPEVYEKLTMLDRVVMAGNCLEVLNLGVL 411
Score = 54.4 bits (125), Expect = 5e-07
Identities = 34/112 (30%), Positives = 52/112 (46%)
Frame = +2
Query: 197 LYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSY 376
LY +++ L L NK+ +FP+ P++IGNL NL L L
Sbjct: 295 LYKFSQLKGLNLSHNKLGLFPILLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDG 354
Query: 377 NPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI 532
N L L E+G+L++L + + +IP+ KLT LD GN L+ +
Sbjct: 355 NFLTTLPEELGNLQQLSSLGISFNNFSQIPEVYEKLTMLDRVVMAGNCLEVL 406
Score = 54.0 bits (124), Expect = 6e-07
Identities = 34/109 (31%), Positives = 52/109 (47%), Gaps = 1/109 (0%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P + + L LNLS N + L +IG+L L+ + L +P+E+G L QL + G
Sbjct: 315 PILLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNFLTTLPEELGNLQQLSSLG 374
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLP-DTMDRMTALVHCNLR 649
N IPE L L + + N +E L ++RM + H +LR
Sbjct: 375 ISFNNFSQIPEVYEKLTMLDRVVMAGNCLEVLNLGVLNRMNHIKHVDLR 423
Score = 33.1 bits (72), Expect = 1.3
Identities = 23/85 (27%), Positives = 41/85 (48%), Gaps = 4/85 (4%)
Frame = +2
Query: 521 LKTIPEEMTSLAKLRWLTLENN--QIETLP--DTMDRMTALVHCNLRNNRLEQFPSSILK 688
L+ +PE + + +L L +N Q+E DT+ + + L NL +N+L FP + +
Sbjct: 261 LEEVPEHLFYSQDITYLNLRHNFMQLERPGGLDTLYKFSQLKGLNLSHNKLGLFPILLCE 320
Query: 689 CKELMFLQLNSNQISSVPANLDTSL 763
L L L+ N +P+ + L
Sbjct: 321 ISTLTELNLSCNGFHDLPSQIGNLL 345
>BC030276-1|AAH30276.1| 529|Homo sapiens LOC220416 protein protein.
Length = 529
Score = 59.3 bits (137), Expect = 2e-08
Identities = 39/124 (31%), Positives = 62/124 (50%)
Frame = +2
Query: 353 LVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI 532
L+ LNLS+N L+ EI L+ L+ +KEIP EI +L L F N + +
Sbjct: 347 LIYLNLSFNDLHYFPTEILCLKNLQILKLRNNPIKEIPSEIQQLEFLRIFTIAFNLITVL 406
Query: 533 PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQ 712
P + SL+ L L + N++ +P+ + ++ +L + N L FP ILK L +Q
Sbjct: 407 PIGLFSLSYLEELDVSYNELTFIPNEIQKLRSLEKLTVDGNELSFFPHGILKL-NLTKIQ 465
Query: 713 LNSN 724
+N
Sbjct: 466 FENN 469
Score = 50.8 bits (116), Expect = 6e-06
Identities = 42/144 (29%), Positives = 58/144 (40%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L+L GF I P L ++ +L L N + FP E P+E
Sbjct: 327 LNLKGFFILNCPDLTPLAFQLIYLNLSFNDLHYFPTEILCLKNLQILKLRNNPIKEIPSE 386
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
I L+ L +++N + VL + L LE + L IP EI KL L+ G
Sbjct: 387 IQQLEFLRIFTIAFNLITVLPIGLFSLSYLEELDVSYNELTFIPNEIQKLRSLEKLTVDG 446
Query: 515 NELKTIPEEMTSLAKLRWLTLENN 586
NEL P + L L + ENN
Sbjct: 447 NELSFFPHGILKL-NLTKIQFENN 469
Score = 39.1 bits (87), Expect = 0.019
Identities = 21/61 (34%), Positives = 30/61 (49%)
Frame = +2
Query: 569 LTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPAN 748
L L+ I PD L++ NL N L FP+ IL K L L+L +N I +P+
Sbjct: 327 LNLKGFFILNCPDLTPLAFQLIYLNLSFNDLHYFPTEILCLKNLQILKLRNNPIKEIPSE 386
Query: 749 L 751
+
Sbjct: 387 I 387
Score = 35.5 bits (78), Expect = 0.24
Identities = 19/76 (25%), Positives = 36/76 (47%)
Frame = +2
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N+L P E+ L L+ L L NN I+ +P + ++ L + N + P +
Sbjct: 355 NDLHYFPTEILCLKNLQILKLRNNPIKEIPSEIQQLEFLRIFTIAFNLITVLPIGLFSLS 414
Query: 695 ELMFLQLNSNQISSVP 742
L L ++ N+++ +P
Sbjct: 415 YLEELDVSYNELTFIP 430
>AL139801-5|CAM14704.1| 506|Homo sapiens similar to Leucine-rich
repeat protein SHOC-2 (Ras-binding protein Sur-8)
protein.
Length = 506
Score = 59.3 bits (137), Expect = 2e-08
Identities = 39/124 (31%), Positives = 62/124 (50%)
Frame = +2
Query: 353 LVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI 532
L+ LNLS+N L+ EI L+ L+ +KEIP EI +L L F N + +
Sbjct: 347 LIYLNLSFNDLHYFPTEILCLKNLQILKLRNNPIKEIPSEIQQLEFLRIFTIAFNLITVL 406
Query: 533 PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQ 712
P + SL+ L L + N++ +P+ + ++ +L + N L FP ILK L +Q
Sbjct: 407 PIGLFSLSYLEELDVSYNELTFIPNEIQKLRSLEKLTVDGNELSFFPHGILKL-NLTKIQ 465
Query: 713 LNSN 724
+N
Sbjct: 466 FENN 469
Score = 50.8 bits (116), Expect = 6e-06
Identities = 42/144 (29%), Positives = 58/144 (40%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L+L GF I P L ++ +L L N + FP E P+E
Sbjct: 327 LNLKGFFILNCPDLTPLAFQLIYLNLSFNDLHYFPTEILCLKNLQILKLRNNPIKEIPSE 386
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
I L+ L +++N + VL + L LE + L IP EI KL L+ G
Sbjct: 387 IQQLEFLRIFTIAFNLITVLPIGLFSLSYLEELDVSYNELTFIPNEIQKLRSLEKLTVDG 446
Query: 515 NELKTIPEEMTSLAKLRWLTLENN 586
NEL P + L L + ENN
Sbjct: 447 NELSFFPHGILKL-NLTKIQFENN 469
Score = 39.1 bits (87), Expect = 0.019
Identities = 21/61 (34%), Positives = 30/61 (49%)
Frame = +2
Query: 569 LTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPAN 748
L L+ I PD L++ NL N L FP+ IL K L L+L +N I +P+
Sbjct: 327 LNLKGFFILNCPDLTPLAFQLIYLNLSFNDLHYFPTEILCLKNLQILKLRNNPIKEIPSE 386
Query: 749 L 751
+
Sbjct: 387 I 387
Score = 35.5 bits (78), Expect = 0.24
Identities = 19/76 (25%), Positives = 36/76 (47%)
Frame = +2
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N+L P E+ L L+ L L NN I+ +P + ++ L + N + P +
Sbjct: 355 NDLHYFPTEILCLKNLQILKLRNNPIKEIPSEIQQLEFLRIFTIAFNLITVLPIGLFSLS 414
Query: 695 ELMFLQLNSNQISSVP 742
L L ++ N+++ +P
Sbjct: 415 YLEELDVSYNELTFIP 430
>AL137141-1|CAI12166.2| 506|Homo sapiens similar to Leucine-rich
repeat protein SHOC-2 (Ras-binding protein Sur-8)
protein.
Length = 506
Score = 59.3 bits (137), Expect = 2e-08
Identities = 39/124 (31%), Positives = 62/124 (50%)
Frame = +2
Query: 353 LVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTI 532
L+ LNLS+N L+ EI L+ L+ +KEIP EI +L L F N + +
Sbjct: 347 LIYLNLSFNDLHYFPTEILCLKNLQILKLRNNPIKEIPSEIQQLEFLRIFTIAFNLITVL 406
Query: 533 PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQ 712
P + SL+ L L + N++ +P+ + ++ +L + N L FP ILK L +Q
Sbjct: 407 PIGLFSLSYLEELDVSYNELTFIPNEIQKLRSLEKLTVDGNELSFFPHGILKL-NLTKIQ 465
Query: 713 LNSN 724
+N
Sbjct: 466 FENN 469
Score = 50.8 bits (116), Expect = 6e-06
Identities = 42/144 (29%), Positives = 58/144 (40%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L+L GF I P L ++ +L L N + FP E P+E
Sbjct: 327 LNLKGFFILNCPDLTPLAFQLIYLNLSFNDLHYFPTEILCLKNLQILKLRNNPIKEIPSE 386
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
I L+ L +++N + VL + L LE + L IP EI KL L+ G
Sbjct: 387 IQQLEFLRIFTIAFNLITVLPIGLFSLSYLEELDVSYNELTFIPNEIQKLRSLEKLTVDG 446
Query: 515 NELKTIPEEMTSLAKLRWLTLENN 586
NEL P + L L + ENN
Sbjct: 447 NELSFFPHGILKL-NLTKIQFENN 469
Score = 39.1 bits (87), Expect = 0.019
Identities = 21/61 (34%), Positives = 30/61 (49%)
Frame = +2
Query: 569 LTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPAN 748
L L+ I PD L++ NL N L FP+ IL K L L+L +N I +P+
Sbjct: 327 LNLKGFFILNCPDLTPLAFQLIYLNLSFNDLHYFPTEILCLKNLQILKLRNNPIKEIPSE 386
Query: 749 L 751
+
Sbjct: 387 I 387
Score = 35.5 bits (78), Expect = 0.24
Identities = 19/76 (25%), Positives = 36/76 (47%)
Frame = +2
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
N+L P E+ L L+ L L NN I+ +P + ++ L + N + P +
Sbjct: 355 NDLHYFPTEILCLKNLQILKLRNNPIKEIPSEIQQLEFLRIFTIAFNLITVLPIGLFSLS 414
Query: 695 ELMFLQLNSNQISSVP 742
L L ++ N+++ +P
Sbjct: 415 YLEELDVSYNELTFIP 430
>BC101065-1|AAI01066.1| 581|Homo sapiens LRRC15 protein protein.
Length = 581
Score = 58.8 bits (136), Expect = 2e-08
Identities = 56/193 (29%), Positives = 81/193 (41%), Gaps = 5/193 (2%)
Frame = +2
Query: 188 PGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLN 367
PGL + ++ LYL N IS P P+ L L L
Sbjct: 238 PGLFHNNHNLQRLYLSNNHISQLP----------------------PSVFMQLPQLNRLT 275
Query: 368 LSYNPLNVLIPEI-GDLEKLEAFWCNRIGLKEIPKEI-GKLTQLDTFGARGNELKTI-PE 538
L N L L P I G + L W + +P + L QL N++ I P
Sbjct: 276 LFGNSLKELSPGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFISPG 335
Query: 539 EMTSLAKLRWLTLENNQIETLPDTMDRMTA-LVHCNLRNNRLEQFPSSIL-KCKELMFLQ 712
L +LR L+L N ++ L + RM A L + +L+NNRL Q P +I LM +Q
Sbjct: 336 AFNGLTELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQ 395
Query: 713 LNSNQISSVPANL 751
L +NQ+ ++P +
Sbjct: 396 LQNNQLENLPLGI 408
>BC101064-1|AAI01065.1| 581|Homo sapiens leucine rich repeat
containing 15 protein.
Length = 581
Score = 58.8 bits (136), Expect = 2e-08
Identities = 56/193 (29%), Positives = 81/193 (41%), Gaps = 5/193 (2%)
Frame = +2
Query: 188 PGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLN 367
PGL + ++ LYL N IS P P+ L L L
Sbjct: 238 PGLFHNNHNLQRLYLSNNHISQLP----------------------PSVFMQLPQLNRLT 275
Query: 368 LSYNPLNVLIPEI-GDLEKLEAFWCNRIGLKEIPKEI-GKLTQLDTFGARGNELKTI-PE 538
L N L L P I G + L W + +P + L QL N++ I P
Sbjct: 276 LFGNSLKELSPGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFISPG 335
Query: 539 EMTSLAKLRWLTLENNQIETLPDTMDRMTA-LVHCNLRNNRLEQFPSSIL-KCKELMFLQ 712
L +LR L+L N ++ L + RM A L + +L+NNRL Q P +I LM +Q
Sbjct: 336 AFNGLTELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQ 395
Query: 713 LNSNQISSVPANL 751
L +NQ+ ++P +
Sbjct: 396 LQNNQLENLPLGI 408
>AF061444-1|AAC77911.1| 907|Homo sapiens G protein-coupled receptor
LGR5 protein.
Length = 907
Score = 58.8 bits (136), Expect = 2e-08
Identities = 50/165 (30%), Positives = 77/165 (46%), Gaps = 5/165 (3%)
Frame = +2
Query: 326 PTE-IGNLKNLVNLNLSYNPLNVLIPE-IGDLEKLEAFWCNRIGLKEIPKEIGK-LTQLD 496
PTE + NL++L +L L N ++ + P L L W + L EIP + + L+ L
Sbjct: 130 PTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQ 189
Query: 497 TFGARGNELKTIPE-EMTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQF 670
N++ IP+ +L+ L L NN+I +L D + +L +L N L++F
Sbjct: 190 AMTLALNKIHHIPDYAFGNLSSWVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEF 249
Query: 671 PSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
P++I L L +SN I S+P P L I NPI
Sbjct: 250 PTAIRTLSNLKELGFHSNNIRSIPEKAFVG-NPSLITIHFYDNPI 293
Score = 42.7 bits (96), Expect = 0.002
Identities = 50/171 (29%), Positives = 75/171 (43%), Gaps = 5/171 (2%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPE---IGDLEKLEA-FWCNRIGLKEIPKEIGKLTQL 493
PT I L NL L N + IPE +G+ + F+ N I L +L
Sbjct: 250 PTAIRTLSNLKELGFHSNNIRS-IPEKAFVGNPSLITIHFYDNPIQFVG-RSAFQHLPEL 307
Query: 494 DTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTM-DRMTALVHCNLRNNRLEQF 670
T G T ++T A L LTL QI +LP T+ +++ L +L N LE
Sbjct: 308 RTLTLNGASQITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDL 367
Query: 671 PSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELSHP 823
PS + C++L + L N+I + + L+ L ++L N I + HP
Sbjct: 368 PSFSV-CQKLQKIDLRHNEIYEIKVDTFQQLL-SLRSLNLAWNKIA-IIHP 415
Score = 40.7 bits (91), Expect = 0.006
Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 3/104 (2%)
Frame = +2
Query: 461 IPKEIGKLTQLDTFGARGNELKTIPE-EMTSLAKLRWLTLENNQIETLP-DTMDRMTALV 634
+P + L L+ GN L IP+ T L L+ L L+NNQ+ +P + + + +L
Sbjct: 82 LPNPLPSLHFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQ 141
Query: 635 HCNLRNNRLEQFPSSILK-CKELMFLQLNSNQISSVPANLDTSL 763
L N + P S L L L+ N ++ +P SL
Sbjct: 142 SLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSL 185
Score = 40.3 bits (90), Expect = 0.008
Identities = 45/201 (22%), Positives = 78/201 (38%), Gaps = 5/201 (2%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXX--XXXXXXXXXXXXXXXXP 328
L LN + E P + T ++ L H N I P +
Sbjct: 239 LDLNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGR 298
Query: 329 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEI-GKLTQLDTFG 505
+ +L L L L+ P++ LE+ + +P+ + +L L
Sbjct: 299 SAFQHLPELRTLTLNGASQITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLD 358
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQI-ETLPDTMDRMTALVHCNLRNNRLEQF-PSS 679
N L+ +P + KL+ + L +N+I E DT ++ +L NL N++ P++
Sbjct: 359 LSYNLLEDLP-SFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNA 417
Query: 680 ILKCKELMFLQLNSNQISSVP 742
L+ L L+SN +SS P
Sbjct: 418 FSTLPSLIKLDLSSNLLSSFP 438
>BC052279-1|AAH52279.1| 307|Homo sapiens leucine rich repeat
containing 59 protein.
Length = 307
Score = 57.6 bits (133), Expect = 5e-08
Identities = 33/101 (32%), Positives = 49/101 (48%), Gaps = 1/101 (0%)
Frame = +2
Query: 452 LKEIP-KEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTA 628
L E+P KE+ L + N+L T+P + L L L L N+++ LP R+
Sbjct: 27 LNEVPVKELAALPKATILDLSCNKLTTLPSDFCGLTHLVKLDLSKNKLQQLPADFGRLVN 86
Query: 629 LVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANL 751
L H +L NN+L P S + K L +L L N + V A +
Sbjct: 87 LQHLDLLNNKLVTLPVSFAQLKNLKWLDLKDNPLDPVLAKV 127
Score = 46.0 bits (104), Expect = 2e-04
Identities = 25/88 (28%), Positives = 42/88 (47%)
Frame = +2
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
E+ L L+LS N L L + L L ++ L+++P + G+L L
Sbjct: 34 ELAALPKATILDLSCNKLTTLPSDFCGLTHLVKLDLSKNKLQQLPADFGRLVNLQHLDLL 93
Query: 512 GNELKTIPEEMTSLAKLRWLTLENNQIE 595
N+L T+P L L+WL L++N ++
Sbjct: 94 NNKLVTLPVSFAQLKNLKWLDLKDNPLD 121
Score = 44.0 bits (99), Expect = 7e-04
Identities = 33/113 (29%), Positives = 58/113 (51%), Gaps = 4/113 (3%)
Frame = +2
Query: 338 GNLKNLVN---LNLSYNPLN-VLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
GNL++ ++ L+LS + LN V + E+ L K + L +P + LT L
Sbjct: 9 GNLRDKLDGNELDLSLSDLNEVPVKELAALPKATILDLSCNKLTTLPSDFCGLTHLVKLD 68
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLE 664
N+L+ +P + L L+ L L NN++ TLP + ++ L +L++N L+
Sbjct: 69 LSKNKLQQLPADFGRLVNLQHLDLLNNKLVTLPVSFAQLKNLKWLDLKDNPLD 121
Score = 30.3 bits (65), Expect = 8.9
Identities = 22/87 (25%), Positives = 35/87 (40%), Gaps = 1/87 (1%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ ++T +P + L L KNK+ P + P
Sbjct: 44 LDLSCNKLTTLPSDFCGLTHLVKLDLSKNKLQQLPADFGRLVNLQHLDLLNNKLVTLPVS 103
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEI-GD 412
LKNL L+L NPL+ ++ ++ GD
Sbjct: 104 FAQLKNLKWLDLKDNPLDPVLAKVAGD 130
>BC017168-1|AAH17168.1| 307|Homo sapiens leucine rich repeat
containing 59 protein.
Length = 307
Score = 57.6 bits (133), Expect = 5e-08
Identities = 33/101 (32%), Positives = 49/101 (48%), Gaps = 1/101 (0%)
Frame = +2
Query: 452 LKEIP-KEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTA 628
L E+P KE+ L + N+L T+P + L L L L N+++ LP R+
Sbjct: 27 LNEVPVKELAALPKATILDLSCNKLTTLPSDFCGLTHLVKLDLSKNKLQQLPADFGRLVN 86
Query: 629 LVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANL 751
L H +L NN+L P S + K L +L L N + V A +
Sbjct: 87 LQHLDLLNNKLVTLPVSFAQLKNLKWLDLKDNPLDPVLAKV 127
Score = 46.0 bits (104), Expect = 2e-04
Identities = 25/88 (28%), Positives = 42/88 (47%)
Frame = +2
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
E+ L L+LS N L L + L L ++ L+++P + G+L L
Sbjct: 34 ELAALPKATILDLSCNKLTTLPSDFCGLTHLVKLDLSKNKLQQLPADFGRLVNLQHLDLL 93
Query: 512 GNELKTIPEEMTSLAKLRWLTLENNQIE 595
N+L T+P L L+WL L++N ++
Sbjct: 94 NNKLVTLPVSFAQLKNLKWLDLKDNPLD 121
Score = 44.0 bits (99), Expect = 7e-04
Identities = 33/113 (29%), Positives = 58/113 (51%), Gaps = 4/113 (3%)
Frame = +2
Query: 338 GNLKNLVN---LNLSYNPLN-VLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
GNL++ ++ L+LS + LN V + E+ L K + L +P + LT L
Sbjct: 9 GNLRDKLDGNELDLSLSDLNEVPVKELAALPKATILDLSCNKLTTLPSDFCGLTHLVKLD 68
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLE 664
N+L+ +P + L L+ L L NN++ TLP + ++ L +L++N L+
Sbjct: 69 LSKNKLQQLPADFGRLVNLQHLDLLNNKLVTLPVSFAQLKNLKWLDLKDNPLD 121
Score = 30.3 bits (65), Expect = 8.9
Identities = 22/87 (25%), Positives = 35/87 (40%), Gaps = 1/87 (1%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ ++T +P + L L KNK+ P + P
Sbjct: 44 LDLSCNKLTTLPSDFCGLTHLVKLDLSKNKLQQLPADFGRLVNLQHLDLLNNKLVTLPVS 103
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEI-GD 412
LKNL L+L NPL+ ++ ++ GD
Sbjct: 104 FAQLKNLKWLDLKDNPLDPVLAKVAGD 130
>BC024001-1|AAH24001.1| 184|Homo sapiens leucine rich repeat
containing 20 protein.
Length = 184
Score = 57.2 bits (132), Expect = 7e-08
Identities = 36/121 (29%), Positives = 60/121 (49%), Gaps = 1/121 (0%)
Frame = +2
Query: 446 IGLKEIPKEIGKLTQLDTFGARGNELKTIPEE-MTSLAKLRWLTLENNQIETLPDTMDRM 622
IG+ ++ + + L T NELK++ + MT+ ++LR L LE N + LP + +
Sbjct: 39 IGIYKVLRNVSGQIHLITLA--NNELKSLTSKFMTTFSQLRELHLEGNFLHRLPSEVSAL 96
Query: 623 TALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNP 802
L +L N+ + FP + L + L N+I VP + +P L I+LR NP
Sbjct: 97 QHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVE-KLAAMPALRSINLRFNP 155
Query: 803 I 805
+
Sbjct: 156 L 156
>AY358318-1|AAQ88684.1| 184|Homo sapiens LKKM2429 protein.
Length = 184
Score = 57.2 bits (132), Expect = 7e-08
Identities = 36/121 (29%), Positives = 60/121 (49%), Gaps = 1/121 (0%)
Frame = +2
Query: 446 IGLKEIPKEIGKLTQLDTFGARGNELKTIPEE-MTSLAKLRWLTLENNQIETLPDTMDRM 622
IG+ ++ + + L T NELK++ + MT+ ++LR L LE N + LP + +
Sbjct: 39 IGIYKVLRNVSGQIHLITLA--NNELKSLTSKFMTTFSQLRELHLEGNFLHRLPSEVSAL 96
Query: 623 TALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNP 802
L +L N+ + FP + L + L N+I VP + +P L I+LR NP
Sbjct: 97 QHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVE-KLAAMPALRSINLRFNP 155
Query: 803 I 805
+
Sbjct: 156 L 156
>AL513211-2|CAI17359.1| 154|Homo sapiens leucine rich repeat
containing 1 protein.
Length = 154
Score = 57.2 bits (132), Expect = 7e-08
Identities = 29/95 (30%), Positives = 50/95 (52%), Gaps = 1/95 (1%)
Frame = +2
Query: 461 IPKEIGKLTQ-LDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVH 637
+P+EI + + L+ N+L+ +PE+ L KLR L L +N+I+ LP + LV
Sbjct: 27 VPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVE 86
Query: 638 CNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVP 742
++ N + + P SI CK L + N ++ +P
Sbjct: 87 LDVSRNEIPEIPESISFCKALQVADFSGNPLTRLP 121
Score = 55.6 bits (128), Expect = 2e-07
Identities = 27/100 (27%), Positives = 53/100 (53%)
Frame = +2
Query: 452 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 631
L+E+P++ +L +L G NE++ +P E+ + +L L + N+I +P+++ AL
Sbjct: 48 LRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNEIPEIPESISFCKAL 107
Query: 632 VHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANL 751
+ N L + P S + + L L +N + S+P N+
Sbjct: 108 QVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENI 147
Score = 50.0 bits (114), Expect = 1e-05
Identities = 32/115 (27%), Positives = 57/115 (49%), Gaps = 3/115 (2%)
Frame = +2
Query: 491 LDTFGARGNELKTIPEEMTSLAK-LRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQ 667
+++ R L +PEE+ A+ L L L+ NQ+ LP+ ++ L L +N +++
Sbjct: 14 VESIDKRHCSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQR 73
Query: 668 FPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL--SHPE 826
P I +L+ L ++ N+I +P ++ S L + D NP+ L S PE
Sbjct: 74 LPPEIANFMQLVELDVSRNEIPEIPESI--SFCKALQVADFSGNPLTRLPESFPE 126
Score = 45.6 bits (103), Expect = 2e-04
Identities = 28/98 (28%), Positives = 45/98 (45%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P + L L L LS N + L PEI + +L +R + EIP+ I L
Sbjct: 52 PEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNEIPEIPESISFCKALQVAD 111
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDR 619
GN L +PE L L L++ + +++LP+ + +
Sbjct: 112 FSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGK 149
Score = 42.7 bits (96), Expect = 0.002
Identities = 29/116 (25%), Positives = 49/116 (42%)
Frame = +2
Query: 347 KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELK 526
++L L L N L L + L KL + ++ +P EI QL NE+
Sbjct: 36 RSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNEIP 95
Query: 527 TIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCK 694
IPE ++ L+ N + LP++ + L ++ + L+ P +I K K
Sbjct: 96 EIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGKQK 151
>AL355138-5|CAI12602.1| 175|Homo sapiens leucine rich repeat
containing 20 protein.
Length = 175
Score = 57.2 bits (132), Expect = 7e-08
Identities = 36/121 (29%), Positives = 60/121 (49%), Gaps = 1/121 (0%)
Frame = +2
Query: 446 IGLKEIPKEIGKLTQLDTFGARGNELKTIPEE-MTSLAKLRWLTLENNQIETLPDTMDRM 622
IG+ ++ + + L T NELK++ + MT+ ++LR L LE N + LP + +
Sbjct: 39 IGIYKVLRNVSGQIHLITLA--NNELKSLTSKFMTTFSQLRELHLEGNFLHRLPSEVSAL 96
Query: 623 TALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNP 802
L +L N+ + FP + L + L N+I VP + +P L I+LR NP
Sbjct: 97 QHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVE-KLAAMPALRSINLRFNP 155
Query: 803 I 805
+
Sbjct: 156 L 156
>AL355138-3|CAI12600.1| 184|Homo sapiens leucine rich repeat
containing 20 protein.
Length = 184
Score = 57.2 bits (132), Expect = 7e-08
Identities = 36/121 (29%), Positives = 60/121 (49%), Gaps = 1/121 (0%)
Frame = +2
Query: 446 IGLKEIPKEIGKLTQLDTFGARGNELKTIPEE-MTSLAKLRWLTLENNQIETLPDTMDRM 622
IG+ ++ + + L T NELK++ + MT+ ++LR L LE N + LP + +
Sbjct: 39 IGIYKVLRNVSGQIHLITLA--NNELKSLTSKFMTTFSQLRELHLEGNFLHRLPSEVSAL 96
Query: 623 TALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNP 802
L +L N+ + FP + L + L N+I VP + +P L I+LR NP
Sbjct: 97 QHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVE-KLAAMPALRSINLRFNP 155
Query: 803 I 805
+
Sbjct: 156 L 156
>AK094734-1|BAC04409.1| 184|Homo sapiens protein ( Homo sapiens
cDNA FLJ37415 fis, clone BRAWH2000232. ).
Length = 184
Score = 57.2 bits (132), Expect = 7e-08
Identities = 36/121 (29%), Positives = 60/121 (49%), Gaps = 1/121 (0%)
Frame = +2
Query: 446 IGLKEIPKEIGKLTQLDTFGARGNELKTIPEE-MTSLAKLRWLTLENNQIETLPDTMDRM 622
IG+ ++ + + L T NELK++ + MT+ ++LR L LE N + LP + +
Sbjct: 39 IGIYKVLRNVSGQIHLITLA--NNELKSLTSKFMTTFSQLRELHLEGNFLHRLPSEVSAL 96
Query: 623 TALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNP 802
L +L N+ + FP + L + L N+I VP + +P L I+LR NP
Sbjct: 97 QHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDVPVE-KLAAMPALRSINLRFNP 155
Query: 803 I 805
+
Sbjct: 156 L 156
>AB071037-1|BAB84587.1| 581|Homo sapiens Lib protein.
Length = 581
Score = 56.8 bits (131), Expect = 9e-08
Identities = 45/147 (30%), Positives = 67/147 (45%), Gaps = 5/147 (3%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEI-GDLEKLEAFWCNRIGLKEIPKEI-GKLTQLDT 499
P+ L L L L N L L I G + L W + +P + L QL
Sbjct: 262 PSIFMQLPQLNRLTLFGNSLKELSLGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQV 321
Query: 500 FGARGNELKTI-PEEMTSLAKLRWLTLENNQIETLPDTMDRMTA-LVHCNLRNNRLEQFP 673
N++ I P L +LR L+L N ++ L + RM A L + +L+NNRL Q P
Sbjct: 322 LILSRNQISFISPGAFNGLTELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLP 381
Query: 674 SSIL-KCKELMFLQLNSNQISSVPANL 751
+I LM +QL +NQ+ ++P +
Sbjct: 382 GNIFANVNGLMAIQLQNNQLENLPLGI 408
>BC032667-1|AAH32667.1| 352|Homo sapiens keratocan protein.
Length = 352
Score = 56.4 bits (130), Expect = 1e-07
Identities = 39/132 (29%), Positives = 69/132 (52%), Gaps = 4/132 (3%)
Frame = +2
Query: 428 AFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEE-MTSLAKLRWLTLENNQIETL- 601
A +C GLKEIP ++ L + N ++TIPE+ + +LRW+ L N+I
Sbjct: 55 ALYCENRGLKEIPAIPSRIWYL---YLQNNLIETIPEKPFENATQLRWINLNKNKITNYG 111
Query: 602 --PDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGL 775
+ ++ L+ L +N LE+ PS + + E LQL N++S +P ++L L
Sbjct: 112 IEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQ--LQLARNKVSRIPQGTFSNL-ENL 168
Query: 776 XMIDLRSNPICE 811
++DL++N + +
Sbjct: 169 TLLDLQNNKLVD 180
Score = 35.9 bits (79), Expect = 0.18
Identities = 24/79 (30%), Positives = 40/79 (50%), Gaps = 3/79 (3%)
Frame = +2
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDT-MDRMTALVHCNLRNNRL--EQFPSSIL 685
N L+ +P + A L L+NN IE +P+ + + + L +N+L E PS
Sbjct: 202 NALRNMPPRLP--ANTMQLFLDNNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGF 259
Query: 686 KCKELMFLQLNSNQISSVP 742
++ LQL+ NQ++ VP
Sbjct: 260 DVSSILDLQLSHNQLTKVP 278
>AF205403-1|AAF69126.1| 352|Homo sapiens keratocan protein.
Length = 352
Score = 56.4 bits (130), Expect = 1e-07
Identities = 39/132 (29%), Positives = 69/132 (52%), Gaps = 4/132 (3%)
Frame = +2
Query: 428 AFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEE-MTSLAKLRWLTLENNQIETL- 601
A +C GLKEIP ++ L + N ++TIPE+ + +LRW+ L N+I
Sbjct: 55 ALYCENRGLKEIPAIPSRIWYL---YLQNNLIETIPEKPFENATQLRWINLNKNKITNYG 111
Query: 602 --PDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGL 775
+ ++ L+ L +N LE+ PS + + E LQL N++S +P ++L L
Sbjct: 112 IEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQ--LQLARNKVSRIPQGTFSNL-ENL 168
Query: 776 XMIDLRSNPICE 811
++DL++N + +
Sbjct: 169 TLLDLQNNKLVD 180
Score = 35.9 bits (79), Expect = 0.18
Identities = 24/79 (30%), Positives = 40/79 (50%), Gaps = 3/79 (3%)
Frame = +2
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDT-MDRMTALVHCNLRNNRL--EQFPSSIL 685
N L+ +P + A L L+NN IE +P+ + + + L +N+L E PS
Sbjct: 202 NALRNMPPRLP--ANTMQLFLDNNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGF 259
Query: 686 KCKELMFLQLNSNQISSVP 742
++ LQL+ NQ++ VP
Sbjct: 260 DVSSILDLQLSHNQLTKVP 278
>AF065988-1|AAC17741.1| 352|Homo sapiens keratocan protein.
Length = 352
Score = 56.4 bits (130), Expect = 1e-07
Identities = 39/132 (29%), Positives = 69/132 (52%), Gaps = 4/132 (3%)
Frame = +2
Query: 428 AFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEE-MTSLAKLRWLTLENNQIETL- 601
A +C GLKEIP ++ L + N ++TIPE+ + +LRW+ L N+I
Sbjct: 55 ALYCENRGLKEIPAIPSRIWYL---YLQNNLIETIPEKPFENATQLRWINLNKNKITNYG 111
Query: 602 --PDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGL 775
+ ++ L+ L +N LE+ PS + + E LQL N++S +P ++L L
Sbjct: 112 IEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQ--LQLARNKVSRIPQGTFSNL-ENL 168
Query: 776 XMIDLRSNPICE 811
++DL++N + +
Sbjct: 169 TLLDLQNNKLVD 180
Score = 35.9 bits (79), Expect = 0.18
Identities = 24/79 (30%), Positives = 40/79 (50%), Gaps = 3/79 (3%)
Frame = +2
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDT-MDRMTALVHCNLRNNRL--EQFPSSIL 685
N L+ +P + A L L+NN IE +P+ + + + L +N+L E PS
Sbjct: 202 NALRNMPPRLP--ANTMQLFLDNNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGF 259
Query: 686 KCKELMFLQLNSNQISSVP 742
++ LQL+ NQ++ VP
Sbjct: 260 DVSSILDLQLSHNQLTKVP 278
>AF063301-1|AAC16390.1| 352|Homo sapiens keratan sulfate
proteoglycan protein.
Length = 352
Score = 56.4 bits (130), Expect = 1e-07
Identities = 39/132 (29%), Positives = 69/132 (52%), Gaps = 4/132 (3%)
Frame = +2
Query: 428 AFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEE-MTSLAKLRWLTLENNQIETL- 601
A +C GLKEIP ++ L + N ++TIPE+ + +LRW+ L N+I
Sbjct: 55 ALYCENRGLKEIPAIPSRIWYL---YLQNNLIETIPEKPFENATQLRWINLNKNKITNYG 111
Query: 602 --PDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGL 775
+ ++ L+ L +N LE+ PS + + E LQL N++S +P ++L L
Sbjct: 112 IEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQ--LQLARNKVSRIPQGTFSNL-ENL 168
Query: 776 XMIDLRSNPICE 811
++DL++N + +
Sbjct: 169 TLLDLQNNKLVD 180
Score = 35.9 bits (79), Expect = 0.18
Identities = 24/79 (30%), Positives = 40/79 (50%), Gaps = 3/79 (3%)
Frame = +2
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDT-MDRMTALVHCNLRNNRL--EQFPSSIL 685
N L+ +P + A L L+NN IE +P+ + + + L +N+L E PS
Sbjct: 202 NALRNMPPRLP--ANTMQLFLDNNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGF 259
Query: 686 KCKELMFLQLNSNQISSVP 742
++ LQL+ NQ++ VP
Sbjct: 260 DVSSILDLQLSHNQLTKVP 278
>AL022344-3|CAI23616.1| 146|Homo sapiens novel protein similar to
Ras suppressor protein 1r 4 (tax-transcriptionally act
protein.
Length = 146
Score = 56.0 bits (129), Expect = 2e-07
Identities = 36/121 (29%), Positives = 57/121 (47%), Gaps = 2/121 (1%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKE--IPKEIGKLTQLDT 499
PT+I L+ L +LNL N LN+ G L LE L E +P LT L
Sbjct: 25 PTQISRLQKLKHLNLGMNRLNISPQGFGSLPALEVLDLTYNNLNENYLPGNFFYLTTLCA 84
Query: 500 FGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSS 679
N+ + +P ++ L KL+ L+ +N + +LP + +T L +++ NRL P
Sbjct: 85 LYLSDNDFEILPPDIGKLTKLQILSNRDNNLISLPKEIRVLTQLKELHIQGNRLTVLPPE 144
Query: 680 I 682
+
Sbjct: 145 L 145
Score = 51.2 bits (117), Expect = 4e-06
Identities = 38/142 (26%), Positives = 62/142 (43%), Gaps = 2/142 (1%)
Frame = +2
Query: 185 IPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNL 364
+P + +E L N+I P + P G+L L L
Sbjct: 1 VPPNIAELKNLEVLNFLNNQIEKLPTQISRLQKLKHLNLGMNRLNISPQGFGSLPALEVL 60
Query: 365 NLSYNPLN--VLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE 538
+L+YN LN L L L A + + + +P +IGKLT+L R N L ++P+
Sbjct: 61 DLTYNNLNENYLPGNFFYLTTLCALYLSDNDFEILPPDIGKLTKLQILSNRDNNLISLPK 120
Query: 539 EMTSLAKLRWLTLENNQIETLP 604
E+ L +L+ L ++ N++ LP
Sbjct: 121 EIRVLTQLKELHIQGNRLTVLP 142
Score = 48.8 bits (111), Expect = 2e-05
Identities = 36/126 (28%), Positives = 53/126 (42%), Gaps = 2/126 (1%)
Frame = +2
Query: 173 EITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXX--XXXXXXXXXXXXXXXXXPTEIGNL 346
+I ++P + +++HL L N+++I P P L
Sbjct: 20 QIEKLPTQISRLQKLKHLNLGMNRLNISPQGFGSLPALEVLDLTYNNLNENYLPGNFFYL 79
Query: 347 KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELK 526
L L LS N +L P+IG L KL+ L +PKEI LTQL +GN L
Sbjct: 80 TTLCALYLSDNDFEILPPDIGKLTKLQILSNRDNNLISLPKEIRVLTQLKELHIQGNRLT 139
Query: 527 TIPEEM 544
+P E+
Sbjct: 140 VLPPEL 145
Score = 43.2 bits (97), Expect = 0.001
Identities = 26/75 (34%), Positives = 33/75 (44%), Gaps = 2/75 (2%)
Frame = +2
Query: 530 IPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFL 709
+P + L L L NNQIE LP + R+ L H NL NRL P L L
Sbjct: 1 VPPNIAELKNLEVLNFLNNQIEKLPTQISRLQKLKHLNLGMNRLNISPQGFGSLPALEVL 60
Query: 710 QLNSNQISS--VPAN 748
L N ++ +P N
Sbjct: 61 DLTYNNLNENYLPGN 75
>BC126277-1|AAI26278.1| 1205|Homo sapiens PH domain and leucine rich
repeat protein phosphatase protein.
Length = 1205
Score = 54.4 bits (125), Expect = 5e-07
Identities = 36/142 (25%), Positives = 65/142 (45%), Gaps = 2/142 (1%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P + ++ L LN+S N L + +G + L+ F + L+ +P E+ + QL G
Sbjct: 195 PLAVCSIPTLAELNVSCNALRSVPAAVGVMHNLQTFLLDGNFLQSLPAELENMKQLSYLG 254
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQ-FPSS 679
NE IPE + L + L + N +ETL + +M + H +LR N + +
Sbjct: 255 LSFNEFTDIPEVLEKLTAVDKLCMSGNCVETLRLQALRKMPHIKHVDLRLNVIRKLIADE 314
Query: 680 ILKCKELMFLQLNSNQISSVPA 745
+ + + L L N++ + A
Sbjct: 315 VDFLQHVTQLDLRDNKLGDLDA 336
Score = 48.0 bits (109), Expect = 4e-05
Identities = 26/101 (25%), Positives = 53/101 (52%)
Frame = +2
Query: 440 NRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDR 619
+R L+ +P+ + + +L+ N++ +P + + LR L +NQ+ LP+ ++R
Sbjct: 390 SRNRLENVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNQLARLPERLER 449
Query: 620 MTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVP 742
+ V N LE P+ ++K L FL ++N++ S+P
Sbjct: 450 TSVEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESLP 490
Score = 47.6 bits (108), Expect = 6e-05
Identities = 52/228 (22%), Positives = 89/228 (39%), Gaps = 6/228 (2%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L + +I E+P L+ + L N+++ P P
Sbjct: 410 LDIGHNQICELPARLFCNSSLRKLLAGHNQLARLPERLERTSVEVLDVQHNQLLELPPNL 469
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEK---LEAFWCNRIGLKE--IPKEIGKLTQLDT 499
+ +L LN S N L L P E L+ + L + +P G L
Sbjct: 470 LMKADSLRFLNASANKLESLPPATLSEETNSILQELYLTNNSLTDKCVPLLTGH-PHLKI 528
Query: 500 FGARGNELKTIP-EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 676
N L++ P +M L +L + L N+++ +P T+ + +N +E FP
Sbjct: 529 LHMAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPE 588
Query: 677 SILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELSH 820
+++ E+ + L+ N++S V L +L P L +DL NP L H
Sbjct: 589 -VMQLPEIKCVDLSCNELSEV--TLPENLPPKLQELDLTGNPRLVLDH 633
Score = 35.1 bits (77), Expect = 0.31
Identities = 22/60 (36%), Positives = 29/60 (48%), Gaps = 6/60 (10%)
Frame = +2
Query: 611 MDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPA------NLDTSLVPG 772
+ R T L NL NN L FP ++ L L ++ N + SVPA NL T L+ G
Sbjct: 175 LQRFTKLKSLNLSNNHLGDFPLAVCSIPTLAELNVSCNALRSVPAAVGVMHNLQTFLLDG 234
Score = 32.3 bits (70), Expect = 2.2
Identities = 19/64 (29%), Positives = 32/64 (50%)
Frame = +2
Query: 560 LRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSV 739
L+ L +N++ L D L + ++ NRLE P + + ++L L + NQI +
Sbjct: 362 LKALYASSNELVQL-DVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICEL 420
Query: 740 PANL 751
PA L
Sbjct: 421 PARL 424
>BC103509-1|AAI03510.1| 958|Homo sapiens SLIT and NTRK-like family,
member 5 protein.
Length = 958
Score = 54.4 bits (125), Expect = 5e-07
Identities = 39/123 (31%), Positives = 57/123 (46%), Gaps = 2/123 (1%)
Frame = +2
Query: 440 NRIGLKEIPKEIGKLTQLDTFGARGNELKTI-PEEMTSLAKLRWLTLENNQIETLPD-TM 613
NRI + + + G LT L GN ++ + PE L L++L L+ N I + T
Sbjct: 443 NRISMIQ-DRAFGDLTNLRRLYLNGNRIERLSPELFYGLQSLQYLFLQYNLIREIQSGTF 501
Query: 614 DRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLR 793
D + L L NN L+ PS + L+ L L SN +S+P + + L IDL
Sbjct: 502 DPVPNLQLLFLNNNLLQAMPSGVFSGLTLLRLNLRSNHFTSLPVSGVLDQLKSLIQIDLH 561
Query: 794 SNP 802
NP
Sbjct: 562 DNP 564
Score = 36.7 bits (81), Expect = 0.10
Identities = 32/85 (37%), Positives = 43/85 (50%), Gaps = 2/85 (2%)
Frame = +2
Query: 551 LAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQF-PSSILKCKELMFLQLNSN 724
L LR L L NN++E L DT + L + + N + P++ K L L LN N
Sbjct: 128 LRGLRRLHLNNNKLELLRDDTFLGLENLEYLQVDYNYISVIEPNAFGKLHLLQVLILNDN 187
Query: 725 QISSVPANLDTSLVPGLXMIDLRSN 799
+SS+P NL VP L +DLR N
Sbjct: 188 LLSSLPNNL-FRFVP-LTHLDLRGN 210
Score = 35.9 bits (79), Expect = 0.18
Identities = 21/66 (31%), Positives = 33/66 (50%), Gaps = 2/66 (3%)
Frame = +2
Query: 533 PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP--SSILKCKELMF 706
P L L+ L L +N + +LP+ + R L H +LR NRL+ P + +++
Sbjct: 170 PNAFGKLHLLQVLILNDNLLSSLPNNLFRFVPLTHLDLRGNRLKLLPYVGLLQHMDKVVE 229
Query: 707 LQLNSN 724
LQL N
Sbjct: 230 LQLEEN 235
>BC098287-1|AAH98287.1| 958|Homo sapiens SLIT and NTRK-like family,
member 5 protein.
Length = 958
Score = 54.4 bits (125), Expect = 5e-07
Identities = 39/123 (31%), Positives = 57/123 (46%), Gaps = 2/123 (1%)
Frame = +2
Query: 440 NRIGLKEIPKEIGKLTQLDTFGARGNELKTI-PEEMTSLAKLRWLTLENNQIETLPD-TM 613
NRI + + + G LT L GN ++ + PE L L++L L+ N I + T
Sbjct: 443 NRISMIQ-DRAFGDLTNLRRLYLNGNRIERLSPELFYGLQSLQYLFLQYNLIREIQSGTF 501
Query: 614 DRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLR 793
D + L L NN L+ PS + L+ L L SN +S+P + + L IDL
Sbjct: 502 DPVPNLQLLFLNNNLLQAMPSGVFSGLTLLRLNLRSNHFTSLPVSGVLDQLKSLIQIDLH 561
Query: 794 SNP 802
NP
Sbjct: 562 DNP 564
Score = 36.7 bits (81), Expect = 0.10
Identities = 32/85 (37%), Positives = 43/85 (50%), Gaps = 2/85 (2%)
Frame = +2
Query: 551 LAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQF-PSSILKCKELMFLQLNSN 724
L LR L L NN++E L DT + L + + N + P++ K L L LN N
Sbjct: 128 LRGLRRLHLNNNKLELLRDDTFLGLENLEYLQVDYNYISVIEPNAFGKLHLLQVLILNDN 187
Query: 725 QISSVPANLDTSLVPGLXMIDLRSN 799
+SS+P NL VP L +DLR N
Sbjct: 188 LLSSLPNNL-FRFVP-LTHLDLRGN 210
Score = 35.9 bits (79), Expect = 0.18
Identities = 21/66 (31%), Positives = 33/66 (50%), Gaps = 2/66 (3%)
Frame = +2
Query: 533 PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP--SSILKCKELMF 706
P L L+ L L +N + +LP+ + R L H +LR NRL+ P + +++
Sbjct: 170 PNAFGKLHLLQVLILNDNLLSSLPNNLFRFVPLTHLDLRGNRLKLLPYVGLLQHMDKVVE 229
Query: 707 LQLNSN 724
LQL N
Sbjct: 230 LQLEEN 235
>BC098106-1|AAH98106.1| 958|Homo sapiens SLIT and NTRK-like family,
member 5 protein.
Length = 958
Score = 54.4 bits (125), Expect = 5e-07
Identities = 39/123 (31%), Positives = 57/123 (46%), Gaps = 2/123 (1%)
Frame = +2
Query: 440 NRIGLKEIPKEIGKLTQLDTFGARGNELKTI-PEEMTSLAKLRWLTLENNQIETLPD-TM 613
NRI + + + G LT L GN ++ + PE L L++L L+ N I + T
Sbjct: 443 NRISMIQ-DRAFGDLTNLRRLYLNGNRIERLSPELFYGLQSLQYLFLQYNLIREIQSGTF 501
Query: 614 DRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLR 793
D + L L NN L+ PS + L+ L L SN +S+P + + L IDL
Sbjct: 502 DPVPNLQLLFLNNNLLQAMPSGVFSGLTLLRLNLRSNHFTSLPVSGVLDQLKSLIQIDLH 561
Query: 794 SNP 802
NP
Sbjct: 562 DNP 564
Score = 36.7 bits (81), Expect = 0.10
Identities = 32/85 (37%), Positives = 43/85 (50%), Gaps = 2/85 (2%)
Frame = +2
Query: 551 LAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQF-PSSILKCKELMFLQLNSN 724
L LR L L NN++E L DT + L + + N + P++ K L L LN N
Sbjct: 128 LRGLRRLHLNNNKLELLRDDTFLGLENLEYLQVDYNYISVIEPNAFGKLHLLQVLILNDN 187
Query: 725 QISSVPANLDTSLVPGLXMIDLRSN 799
+SS+P NL VP L +DLR N
Sbjct: 188 LLSSLPNNL-FRFVP-LTHLDLRGN 210
Score = 35.9 bits (79), Expect = 0.18
Identities = 21/66 (31%), Positives = 33/66 (50%), Gaps = 2/66 (3%)
Frame = +2
Query: 533 PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP--SSILKCKELMF 706
P L L+ L L +N + +LP+ + R L H +LR NRL+ P + +++
Sbjct: 170 PNAFGKLHLLQVLILNDNLLSSLPNNLFRFVPLTHLDLRGNRLKLLPYVGLLQHMDKVVE 229
Query: 707 LQLNSN 724
LQL N
Sbjct: 230 LQLEEN 235
>BC014927-1|AAH14927.3| 1205|Homo sapiens PH domain and leucine rich
repeat protein phosphatase protein.
Length = 1205
Score = 54.4 bits (125), Expect = 5e-07
Identities = 36/142 (25%), Positives = 65/142 (45%), Gaps = 2/142 (1%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P + ++ L LN+S N L + +G + L+ F + L+ +P E+ + QL G
Sbjct: 195 PLAVCSIPTLAELNVSCNALRSVPAAVGVMHNLQTFLLDGNFLQSLPAELENMKQLSYLG 254
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQ-FPSS 679
NE IPE + L + L + N +ETL + +M + H +LR N + +
Sbjct: 255 LSFNEFTDIPEVLEKLTAVDKLCMSGNCVETLRLQALRKMPHIKHVDLRLNVIRKLIADE 314
Query: 680 ILKCKELMFLQLNSNQISSVPA 745
+ + + L L N++ + A
Sbjct: 315 VDFLQHVTQLDLRDNKLGDLDA 336
Score = 48.0 bits (109), Expect = 4e-05
Identities = 26/101 (25%), Positives = 53/101 (52%)
Frame = +2
Query: 440 NRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDR 619
+R L+ +P+ + + +L+ N++ +P + + LR L +NQ+ LP+ ++R
Sbjct: 390 SRNRLENVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNQLARLPERLER 449
Query: 620 MTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVP 742
+ V N LE P+ ++K L FL ++N++ S+P
Sbjct: 450 TSVEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESLP 490
Score = 47.6 bits (108), Expect = 6e-05
Identities = 52/228 (22%), Positives = 89/228 (39%), Gaps = 6/228 (2%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L + +I E+P L+ + L N+++ P P
Sbjct: 410 LDIGHNQICELPARLFCNSSLRKLLAGHNQLARLPERLERTSVEVLDVQHNQLLELPPNL 469
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEK---LEAFWCNRIGLKE--IPKEIGKLTQLDT 499
+ +L LN S N L L P E L+ + L + +P G L
Sbjct: 470 LMKADSLRFLNASANKLESLPPATLSEETNSILQELYLTNNSLTDKCVPLLTGH-PHLKI 528
Query: 500 FGARGNELKTIP-EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 676
N L++ P +M L +L + L N+++ +P T+ + +N +E FP
Sbjct: 529 LHMAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPE 588
Query: 677 SILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELSH 820
+++ E+ + L+ N++S V L +L P L +DL NP L H
Sbjct: 589 -VMQLPEIKCVDLSCNELSEV--TLPENLPPKLQELDLTGNPRLVLDH 633
Score = 35.1 bits (77), Expect = 0.31
Identities = 22/60 (36%), Positives = 29/60 (48%), Gaps = 6/60 (10%)
Frame = +2
Query: 611 MDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPA------NLDTSLVPG 772
+ R T L NL NN L FP ++ L L ++ N + SVPA NL T L+ G
Sbjct: 175 LQRFTKLKSLNLSNNHLGDFPLAVCSIPTLAELNVSCNALRSVPAAVGVMHNLQTFLLDG 234
Score = 32.3 bits (70), Expect = 2.2
Identities = 19/64 (29%), Positives = 32/64 (50%)
Frame = +2
Query: 560 LRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSV 739
L+ L +N++ L D L + ++ NRLE P + + ++L L + NQI +
Sbjct: 362 LKALYASSNELVQL-DVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICEL 420
Query: 740 PANL 751
PA L
Sbjct: 421 PARL 424
>AL603883-1|CAH73026.1| 958|Homo sapiens SLIT and NTRK-like family,
member 5 protein.
Length = 958
Score = 54.4 bits (125), Expect = 5e-07
Identities = 39/123 (31%), Positives = 57/123 (46%), Gaps = 2/123 (1%)
Frame = +2
Query: 440 NRIGLKEIPKEIGKLTQLDTFGARGNELKTI-PEEMTSLAKLRWLTLENNQIETLPD-TM 613
NRI + + + G LT L GN ++ + PE L L++L L+ N I + T
Sbjct: 443 NRISMIQ-DRAFGDLTNLRRLYLNGNRIERLSPELFYGLQSLQYLFLQYNLIREIQSGTF 501
Query: 614 DRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLR 793
D + L L NN L+ PS + L+ L L SN +S+P + + L IDL
Sbjct: 502 DPVPNLQLLFLNNNLLQAMPSGVFSGLTLLRLNLRSNHFTSLPVSGVLDQLKSLIQIDLH 561
Query: 794 SNP 802
NP
Sbjct: 562 DNP 564
Score = 36.7 bits (81), Expect = 0.10
Identities = 32/85 (37%), Positives = 43/85 (50%), Gaps = 2/85 (2%)
Frame = +2
Query: 551 LAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQF-PSSILKCKELMFLQLNSN 724
L LR L L NN++E L DT + L + + N + P++ K L L LN N
Sbjct: 128 LRGLRRLHLNNNKLELLRDDTFLGLENLEYLQVDYNYISVIEPNAFGKLHLLQVLILNDN 187
Query: 725 QISSVPANLDTSLVPGLXMIDLRSN 799
+SS+P NL VP L +DLR N
Sbjct: 188 LLSSLPNNL-FRFVP-LTHLDLRGN 210
Score = 35.9 bits (79), Expect = 0.18
Identities = 21/66 (31%), Positives = 33/66 (50%), Gaps = 2/66 (3%)
Frame = +2
Query: 533 PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP--SSILKCKELMF 706
P L L+ L L +N + +LP+ + R L H +LR NRL+ P + +++
Sbjct: 170 PNAFGKLHLLQVLILNDNLLSSLPNNLFRFVPLTHLDLRGNRLKLLPYVGLLQHMDKVVE 229
Query: 707 LQLNSN 724
LQL N
Sbjct: 230 LQLEEN 235
>AK001924-1|BAA91980.1| 721|Homo sapiens protein ( Homo sapiens
cDNA FLJ11062 fis, clone PLACE1004804, weakly similar to
ADENYLATE CYCLASE (EC 4.6.1.1). ).
Length = 721
Score = 54.4 bits (125), Expect = 5e-07
Identities = 36/142 (25%), Positives = 65/142 (45%), Gaps = 2/142 (1%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P + ++ L LN+S N L + +G + L+ F + L+ +P E+ + QL G
Sbjct: 195 PLAVCSIPTLAELNVSCNALRSVPAAVGVMHNLQTFLLDGNFLQSLPAELENMKQLSYLG 254
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQ-FPSS 679
NE IPE + L + L + N +ETL + +M + H +LR N + +
Sbjct: 255 LSFNEFTDIPEVLEKLTAVDKLCMSGNCVETLRLQALRKMPHIKHVDLRLNVIRKLIADE 314
Query: 680 ILKCKELMFLQLNSNQISSVPA 745
+ + + L L N++ + A
Sbjct: 315 VDFLQHVTQLDLRDNKLGDLDA 336
Score = 48.0 bits (109), Expect = 4e-05
Identities = 26/101 (25%), Positives = 53/101 (52%)
Frame = +2
Query: 440 NRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDR 619
+R L+ +P+ + + +L+ N++ +P + + LR L +NQ+ LP+ ++R
Sbjct: 390 SRNRLENVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNQLARLPERLER 449
Query: 620 MTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVP 742
+ V N LE P+ ++K L FL ++N++ S+P
Sbjct: 450 TSVEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESLP 490
Score = 47.6 bits (108), Expect = 6e-05
Identities = 52/228 (22%), Positives = 89/228 (39%), Gaps = 6/228 (2%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L + +I E+P L+ + L N+++ P P
Sbjct: 410 LDIGHNQICELPARLFCNSSLRKLLAGHNQLARLPERLERTSVEVLDVQHNQLLELPPNL 469
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEK---LEAFWCNRIGLKE--IPKEIGKLTQLDT 499
+ +L LN S N L L P E L+ + L + +P G L
Sbjct: 470 LMKADSLRFLNASANKLESLPPATLSEETNSILQELYLTNNSLTDKCVPLLTGH-PHLKI 528
Query: 500 FGARGNELKTIP-EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 676
N L++ P +M L +L + L N+++ +P T+ + +N +E FP
Sbjct: 529 LHMAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPE 588
Query: 677 SILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELSH 820
+++ E+ + L+ N++S V L +L P L +DL NP L H
Sbjct: 589 -VMQLPEIKCVDLSCNELSEV--TLPENLPPKLQELDLTGNPRLVLDH 633
Score = 38.7 bits (86), Expect = 0.026
Identities = 21/72 (29%), Positives = 34/72 (47%)
Frame = +2
Query: 539 EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLN 718
E+ AKL+ L L NN + P + + L N+ N L P+++ L L+
Sbjct: 174 ELQRFAKLKSLNLSNNHLGDFPLAVCSIPTLAELNVSCNALRSVPAAVGVMHNLQTFLLD 233
Query: 719 SNQISSVPANLD 754
N + S+PA L+
Sbjct: 234 GNFLQSLPAELE 245
Score = 32.3 bits (70), Expect = 2.2
Identities = 19/64 (29%), Positives = 32/64 (50%)
Frame = +2
Query: 560 LRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSV 739
L+ L +N++ L D L + ++ NRLE P + + ++L L + NQI +
Sbjct: 362 LKALYASSNELVQL-DVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICEL 420
Query: 740 PANL 751
PA L
Sbjct: 421 PARL 424
>AB020725-1|BAA74941.1| 966|Homo sapiens KIAA0918 protein protein.
Length = 966
Score = 54.4 bits (125), Expect = 5e-07
Identities = 39/123 (31%), Positives = 57/123 (46%), Gaps = 2/123 (1%)
Frame = +2
Query: 440 NRIGLKEIPKEIGKLTQLDTFGARGNELKTI-PEEMTSLAKLRWLTLENNQIETLPD-TM 613
NRI + + + G LT L GN ++ + PE L L++L L+ N I + T
Sbjct: 451 NRISMIQ-DRAFGDLTNLRRLYLNGNRIERLSPELFYGLQSLQYLFLQYNLIREIQSGTF 509
Query: 614 DRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLR 793
D + L L NN L+ PS + L+ L L SN +S+P + + L IDL
Sbjct: 510 DPVPNLQLLFLNNNLLQAMPSGVFSGLTLLRLNLRSNHFTSLPVSGVLDQLKSLIQIDLH 569
Query: 794 SNP 802
NP
Sbjct: 570 DNP 572
Score = 36.7 bits (81), Expect = 0.10
Identities = 32/85 (37%), Positives = 43/85 (50%), Gaps = 2/85 (2%)
Frame = +2
Query: 551 LAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQF-PSSILKCKELMFLQLNSN 724
L LR L L NN++E L DT + L + + N + P++ K L L LN N
Sbjct: 136 LRGLRRLHLNNNKLELLRDDTFLGLENLEYLQVDYNYISVIEPNAFGKLHLLQVLILNDN 195
Query: 725 QISSVPANLDTSLVPGLXMIDLRSN 799
+SS+P NL VP L +DLR N
Sbjct: 196 LLSSLPNNL-FRFVP-LTHLDLRGN 218
Score = 35.9 bits (79), Expect = 0.18
Identities = 21/66 (31%), Positives = 33/66 (50%), Gaps = 2/66 (3%)
Frame = +2
Query: 533 PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP--SSILKCKELMF 706
P L L+ L L +N + +LP+ + R L H +LR NRL+ P + +++
Sbjct: 178 PNAFGKLHLLQVLILNDNLLSSLPNNLFRFVPLTHLDLRGNRLKLLPYVGLLQHMDKVVE 237
Query: 707 LQLNSN 724
LQL N
Sbjct: 238 LQLEEN 243
>AB011178-1|BAA25532.2| 1369|Homo sapiens KIAA0606 protein protein.
Length = 1369
Score = 54.4 bits (125), Expect = 5e-07
Identities = 36/142 (25%), Positives = 65/142 (45%), Gaps = 2/142 (1%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P + ++ L LN+S N L + +G + L+ F + L+ +P E+ + QL G
Sbjct: 359 PLAVCSIPTLAELNVSCNALRSVPAAVGVMHNLQTFLLDGNFLQSLPAELENMKQLSYLG 418
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQ-FPSS 679
NE IPE + L + L + N +ETL + +M + H +LR N + +
Sbjct: 419 LSFNEFTDIPEVLEKLTAVDKLCMSGNCVETLRLQALRKMPHIKHVDLRLNVIRKLIADE 478
Query: 680 ILKCKELMFLQLNSNQISSVPA 745
+ + + L L N++ + A
Sbjct: 479 VDFLQHVTQLDLRDNKLGDLDA 500
Score = 48.4 bits (110), Expect = 3e-05
Identities = 52/228 (22%), Positives = 90/228 (39%), Gaps = 6/228 (2%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L + +I E+P L+ + L N+++ P P
Sbjct: 574 LDIGHNQICELPARLFCNSSLRKLLAGHNQLARLPERLERTSVEVLDVQHNQLLELPPNL 633
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEK---LEAFWCNRIGLKE--IPKEIGKLTQLDT 499
+ +L LN S N L L P E L+ + L + +P G L
Sbjct: 634 LMKADSLRFLNASANKLESLPPATLSEETNSILQELYLTNNSLTDKCVPLLTGH-PHLKI 692
Query: 500 FGARGNELKTIP-EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 676
N L++ P +M L +L + L N+++ +P T+ + + +N +E FP
Sbjct: 693 LHMAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMNCSRMHTVIAHSNCIEVFPE 752
Query: 677 SILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELSH 820
+++ E+ + L+ N++S V L +L P L +DL NP L H
Sbjct: 753 -VMQLPEIKCVDLSCNELSEV--TLPENLPPKLQELDLTGNPRLVLDH 797
Score = 48.0 bits (109), Expect = 4e-05
Identities = 26/101 (25%), Positives = 53/101 (52%)
Frame = +2
Query: 440 NRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDR 619
+R L+ +P+ + + +L+ N++ +P + + LR L +NQ+ LP+ ++R
Sbjct: 554 SRNRLENVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNQLARLPERLER 613
Query: 620 MTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVP 742
+ V N LE P+ ++K L FL ++N++ S+P
Sbjct: 614 TSVEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESLP 654
Score = 35.1 bits (77), Expect = 0.31
Identities = 22/60 (36%), Positives = 29/60 (48%), Gaps = 6/60 (10%)
Frame = +2
Query: 611 MDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPA------NLDTSLVPG 772
+ R T L NL NN L FP ++ L L ++ N + SVPA NL T L+ G
Sbjct: 339 LQRFTKLKSLNLSNNHLGDFPLAVCSIPTLAELNVSCNALRSVPAAVGVMHNLQTFLLDG 398
Score = 32.3 bits (70), Expect = 2.2
Identities = 19/64 (29%), Positives = 32/64 (50%)
Frame = +2
Query: 560 LRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSV 739
L+ L +N++ L D L + ++ NRLE P + + ++L L + NQI +
Sbjct: 526 LKALYASSNELVQL-DVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICEL 584
Query: 740 PANL 751
PA L
Sbjct: 585 PARL 588
>BC117472-1|AAI17473.1| 763|Homo sapiens LRCH1 protein protein.
Length = 763
Score = 54.0 bits (124), Expect = 6e-07
Identities = 30/100 (30%), Positives = 51/100 (51%)
Frame = +2
Query: 452 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 631
L E+P E+ L+ N ++ IPE + +L L +L L NQ+ LP + +
Sbjct: 109 LVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLPLK 168
Query: 632 VHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANL 751
V NN+L P I + K+LM L ++ N+I+++P +
Sbjct: 169 V-LIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQI 207
Score = 53.2 bits (122), Expect = 1e-06
Identities = 38/139 (27%), Positives = 69/139 (49%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P E+ + +L LNL +N + V+ I +L+ L +R L +P + L L
Sbjct: 113 PMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLP-LKVLI 171
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
A N+L ++PEE+ L +L L + N+I LP + ++ +L N+R N L+ P ++
Sbjct: 172 ASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELV 231
Query: 686 KCKELMFLQLNSNQISSVP 742
+ F + N++ +P
Sbjct: 232 DLPLVKF-DFSCNKVLVIP 249
Score = 46.8 bits (106), Expect = 1e-04
Identities = 37/143 (25%), Positives = 64/143 (44%), Gaps = 1/143 (0%)
Frame = +2
Query: 341 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 520
+L + V +LS N L + E+ LE ++ IP+ I L L N+
Sbjct: 95 DLSDTVQADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQ 154
Query: 521 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 700
L +P + L L+ L NN++ +LP+ + ++ L+ ++ N + P I + K L
Sbjct: 155 LSALPACLCGLP-LKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSL 213
Query: 701 MFLQLNSNQISSVPANL-DTSLV 766
L + N + +P L D LV
Sbjct: 214 RELNVRRNYLKVLPQELVDLPLV 236
>BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2 (Drosophila)
protein.
Length = 1529
Score = 54.0 bits (124), Expect = 6e-07
Identities = 39/125 (31%), Positives = 59/125 (47%), Gaps = 2/125 (1%)
Frame = +2
Query: 437 CNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPD-TM 613
C+ GLK +PK I + + GN+ +P+E+++ L + L NN+I TL + +
Sbjct: 740 CSNKGLKVLPKGIPR--DVTELYLDGNQFTLVPKELSNYKHLTLIDLSNNRISTLSNQSF 797
Query: 614 DRMTALVHCNLRNNRLEQFPSSILK-CKELMFLQLNSNQISSVPANLDTSLVPGLXMIDL 790
MT L+ L NRL P K L L L+ N IS VP L L + +
Sbjct: 798 SNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDL-SALSHLAI 856
Query: 791 RSNPI 805
+NP+
Sbjct: 857 GANPL 861
Score = 43.6 bits (98), Expect = 9e-04
Identities = 37/126 (29%), Positives = 57/126 (45%), Gaps = 3/126 (2%)
Frame = +2
Query: 437 CNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTS-LAKLRWLTLENNQI-ETLPDT 610
C GL EIP + + + N +K IP S KLR + L NNQI E PD
Sbjct: 286 CRGKGLTEIPTNLPET--ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDA 343
Query: 611 MDRMTALVHCNLRNNRLEQFPSSILK-CKELMFLQLNSNQISSVPANLDTSLVPGLXMID 787
+ +L L N++ + P S+ + L L LN+N+I+ + + L L ++
Sbjct: 344 FQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDL-HNLNLLS 402
Query: 788 LRSNPI 805
L N +
Sbjct: 403 LYDNKL 408
Score = 30.7 bits (66), Expect = 6.8
Identities = 29/109 (26%), Positives = 47/109 (43%), Gaps = 3/109 (2%)
Frame = +2
Query: 482 LTQLDTFGARGNELKTIPEEM-TSLAKLRWLTLENNQIETLPDTMDR-MTALVHCNLRNN 655
L +L+ N L+ PE + AKL L L NQI+ +P R + + L N
Sbjct: 102 LKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYN 161
Query: 656 RLEQFPSSILKC-KELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSN 799
++ + ++L L LN+N I+ + + +P L L SN
Sbjct: 162 QISCIEDGAFRALRDLEVLTLNNNNITRLSV-ASFNHMPKLRTFRLHSN 209
>BC112937-1|AAI12938.1| 696|Homo sapiens LRCH1 protein protein.
Length = 696
Score = 54.0 bits (124), Expect = 6e-07
Identities = 30/100 (30%), Positives = 51/100 (51%)
Frame = +2
Query: 452 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 631
L E+P E+ L+ N ++ IPE + +L L +L L NQ+ LP + +
Sbjct: 109 LVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLPLK 168
Query: 632 VHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANL 751
V NN+L P I + K+LM L ++ N+I+++P +
Sbjct: 169 V-LIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQI 207
Score = 53.2 bits (122), Expect = 1e-06
Identities = 38/139 (27%), Positives = 69/139 (49%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P E+ + +L LNL +N + V+ I +L+ L +R L +P + L L
Sbjct: 113 PMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLP-LKVLI 171
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
A N+L ++PEE+ L +L L + N+I LP + ++ +L N+R N L+ P ++
Sbjct: 172 ASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELV 231
Query: 686 KCKELMFLQLNSNQISSVP 742
+ F + N++ +P
Sbjct: 232 DLPLVKF-DFSCNKVLVIP 249
Score = 46.8 bits (106), Expect = 1e-04
Identities = 37/143 (25%), Positives = 64/143 (44%), Gaps = 1/143 (0%)
Frame = +2
Query: 341 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 520
+L + V +LS N L + E+ LE ++ IP+ I L L N+
Sbjct: 95 DLSDTVQADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQ 154
Query: 521 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 700
L +P + L L+ L NN++ +LP+ + ++ L+ ++ N + P I + K L
Sbjct: 155 LSALPACLCGLP-LKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSL 213
Query: 701 MFLQLNSNQISSVPANL-DTSLV 766
L + N + +P L D LV
Sbjct: 214 RELNVRRNYLKVLPQELVDLPLV 236
>BC033039-1|AAH33039.1| 927|Homo sapiens LGR4 protein protein.
Length = 927
Score = 54.0 bits (124), Expect = 6e-07
Identities = 40/129 (31%), Positives = 65/129 (50%), Gaps = 3/129 (2%)
Frame = +2
Query: 437 CNRIGLKEIPKEIGKLTQLDTFGARGNELKTI-PEEMTSLAKLRWLTLENNQIETLPDTM 613
C+ GL +P+ + TQ GN+L I P+ ++ L +L+ LTL+NNQ++T+P
Sbjct: 43 CSGKGLTAVPEGLSAFTQ--ALQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEA 100
Query: 614 DR-MTALVHCNLRNNRLEQFP-SSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMID 787
R ++AL L N + P S +L L L+ N ++ VP + S +P L +
Sbjct: 101 IRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVH-HLSNLPTLQALT 159
Query: 788 LRSNPICEL 814
L N I +
Sbjct: 160 LALNKISSI 168
Score = 49.6 bits (113), Expect = 1e-05
Identities = 59/227 (25%), Positives = 93/227 (40%), Gaps = 7/227 (3%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCL-EVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
L L+ IT +P + L ++ HL+L N ++ PV
Sbjct: 110 LRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHHLSNLPTLQALTLALNKISSIP 169
Query: 332 EIG--NLKNLVNLNLSYNPLNVLIPEIGD-LEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
+ NL +LV L+L N + L D L+ LE N L E P+ I L L
Sbjct: 170 DFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEFPQAIKALPSLKEL 229
Query: 503 GARGNELKTIPE-EMTSLAKLRWLTLENNQIETLPDT-MDRMTALVHCNLRN-NRLEQFP 673
G N + IP+ LR + L +N + + ++ ++ L +R + ++QFP
Sbjct: 230 GFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASMVQQFP 289
Query: 674 SSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
++ L L L +ISS+P NL L +DL N I +L
Sbjct: 290 -NLTGTVHLESLTLTGTKISSIPNNL-CQEQKMLRTLDLSYNNIRDL 334
>AY050632-1|AAK95568.1| 728|Homo sapiens neuronal protein isoform B
protein.
Length = 728
Score = 54.0 bits (124), Expect = 6e-07
Identities = 30/100 (30%), Positives = 51/100 (51%)
Frame = +2
Query: 452 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 631
L E+P E+ L+ N ++ IPE + +L L +L L NQ+ LP + +
Sbjct: 109 LVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLPLK 168
Query: 632 VHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANL 751
V NN+L P I + K+LM L ++ N+I+++P +
Sbjct: 169 V-LIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQI 207
Score = 53.2 bits (122), Expect = 1e-06
Identities = 38/139 (27%), Positives = 69/139 (49%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P E+ + +L LNL +N + V+ I +L+ L +R L +P + L L
Sbjct: 113 PMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLP-LKVLI 171
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
A N+L ++PEE+ L +L L + N+I LP + ++ +L N+R N L+ P ++
Sbjct: 172 ASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELV 231
Query: 686 KCKELMFLQLNSNQISSVP 742
+ F + N++ +P
Sbjct: 232 DLPLVKF-DFSCNKVLVIP 249
Score = 46.8 bits (106), Expect = 1e-04
Identities = 37/143 (25%), Positives = 64/143 (44%), Gaps = 1/143 (0%)
Frame = +2
Query: 341 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 520
+L + V +LS N L + E+ LE ++ IP+ I L L N+
Sbjct: 95 DLSDTVQADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQ 154
Query: 521 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 700
L +P + L L+ L NN++ +LP+ + ++ L+ ++ N + P I + K L
Sbjct: 155 LSALPACLCGLP-LKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSL 213
Query: 701 MFLQLNSNQISSVPANL-DTSLV 766
L + N + +P L D LV
Sbjct: 214 RELNVRRNYLKVLPQELVDLPLV 236
>AY050631-1|AAK95567.1| 696|Homo sapiens neuronal protein isoform a
protein.
Length = 696
Score = 54.0 bits (124), Expect = 6e-07
Identities = 30/100 (30%), Positives = 51/100 (51%)
Frame = +2
Query: 452 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 631
L E+P E+ L+ N ++ IPE + +L L +L L NQ+ LP + +
Sbjct: 109 LVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLPLK 168
Query: 632 VHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANL 751
V NN+L P I + K+LM L ++ N+I+++P +
Sbjct: 169 V-LIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQI 207
Score = 53.2 bits (122), Expect = 1e-06
Identities = 38/139 (27%), Positives = 69/139 (49%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P E+ + +L LNL +N + V+ I +L+ L +R L +P + L L
Sbjct: 113 PMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLP-LKVLI 171
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
A N+L ++PEE+ L +L L + N+I LP + ++ +L N+R N L+ P ++
Sbjct: 172 ASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELV 231
Query: 686 KCKELMFLQLNSNQISSVP 742
+ F + N++ +P
Sbjct: 232 DLPLVKF-DFSCNKVLVIP 249
Score = 46.8 bits (106), Expect = 1e-04
Identities = 37/143 (25%), Positives = 64/143 (44%), Gaps = 1/143 (0%)
Frame = +2
Query: 341 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 520
+L + V +LS N L + E+ LE ++ IP+ I L L N+
Sbjct: 95 DLSDTVQADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQ 154
Query: 521 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 700
L +P + L L+ L NN++ +LP+ + ++ L+ ++ N + P I + K L
Sbjct: 155 LSALPACLCGLP-LKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSL 213
Query: 701 MFLQLNSNQISSVPANL-DTSLV 766
L + N + +P L D LV
Sbjct: 214 RELNVRRNYLKVLPQELVDLPLV 236
>AL359880-1|CAH70792.1| 734|Homo sapiens leucine-rich repeats and
calponin homology (CH) domain containing 1 protein.
Length = 734
Score = 54.0 bits (124), Expect = 6e-07
Identities = 30/100 (30%), Positives = 51/100 (51%)
Frame = +2
Query: 452 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 631
L E+P E+ L+ N ++ IPE + +L L +L L NQ+ LP + +
Sbjct: 109 LVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLPLK 168
Query: 632 VHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANL 751
V NN+L P I + K+LM L ++ N+I+++P +
Sbjct: 169 V-LIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQI 207
Score = 53.6 bits (123), Expect = 8e-07
Identities = 38/139 (27%), Positives = 69/139 (49%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P E+ + +L LNL +N + V+ I +L+ L +R L +P + L L
Sbjct: 113 PMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLP-LKVLI 171
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
A N+L ++PEE+ L +L L + N+I LP + ++ +L N+R N L+ P ++
Sbjct: 172 ASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELV 231
Query: 686 KCKELMFLQLNSNQISSVP 742
+ F + N++ +P
Sbjct: 232 DLSLVKF-DFSCNKVLVIP 249
Score = 48.8 bits (111), Expect = 2e-05
Identities = 38/143 (26%), Positives = 65/143 (45%), Gaps = 1/143 (0%)
Frame = +2
Query: 341 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 520
+L + V +LS N L + E+ LE ++ IP+ I L L N+
Sbjct: 95 DLSDTVQADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQ 154
Query: 521 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 700
L +P + L L+ L NN++ +LP+ + ++ L+ ++ N + P I + K L
Sbjct: 155 LSALPACLCGLP-LKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSL 213
Query: 701 MFLQLNSNQISSVPANL-DTSLV 766
L + N + +P L D SLV
Sbjct: 214 RELNVRRNYLKVLPQELVDLSLV 236
>AL138704-1|CAH73642.1| 734|Homo sapiens leucine-rich repeats and
calponin homology (CH) domain containing 1 protein.
Length = 734
Score = 54.0 bits (124), Expect = 6e-07
Identities = 30/100 (30%), Positives = 51/100 (51%)
Frame = +2
Query: 452 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 631
L E+P E+ L+ N ++ IPE + +L L +L L NQ+ LP + +
Sbjct: 109 LVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLPLK 168
Query: 632 VHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANL 751
V NN+L P I + K+LM L ++ N+I+++P +
Sbjct: 169 V-LIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQI 207
Score = 53.6 bits (123), Expect = 8e-07
Identities = 38/139 (27%), Positives = 69/139 (49%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P E+ + +L LNL +N + V+ I +L+ L +R L +P + L L
Sbjct: 113 PMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLP-LKVLI 171
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
A N+L ++PEE+ L +L L + N+I LP + ++ +L N+R N L+ P ++
Sbjct: 172 ASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELV 231
Query: 686 KCKELMFLQLNSNQISSVP 742
+ F + N++ +P
Sbjct: 232 DLSLVKF-DFSCNKVLVIP 249
Score = 48.8 bits (111), Expect = 2e-05
Identities = 38/143 (26%), Positives = 65/143 (45%), Gaps = 1/143 (0%)
Frame = +2
Query: 341 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 520
+L + V +LS N L + E+ LE ++ IP+ I L L N+
Sbjct: 95 DLSDTVQADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQ 154
Query: 521 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 700
L +P + L L+ L NN++ +LP+ + ++ L+ ++ N + P I + K L
Sbjct: 155 LSALPACLCGLP-LKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSL 213
Query: 701 MFLQLNSNQISSVPANL-DTSLV 766
L + N + +P L D SLV
Sbjct: 214 RELNVRRNYLKVLPQELVDLSLV 236
>AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein.
Length = 1525
Score = 54.0 bits (124), Expect = 6e-07
Identities = 39/125 (31%), Positives = 59/125 (47%), Gaps = 2/125 (1%)
Frame = +2
Query: 437 CNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPD-TM 613
C+ GLK +PK I + + GN+ +P+E+++ L + L NN+I TL + +
Sbjct: 736 CSNKGLKVLPKGIPR--DVTELYLDGNQFTLVPKELSNYKHLTLIDLSNNRISTLSNQSF 793
Query: 614 DRMTALVHCNLRNNRLEQFPSSILK-CKELMFLQLNSNQISSVPANLDTSLVPGLXMIDL 790
MT L+ L NRL P K L L L+ N IS VP L L + +
Sbjct: 794 SNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDL-SALSHLAI 852
Query: 791 RSNPI 805
+NP+
Sbjct: 853 GANPL 857
Score = 43.6 bits (98), Expect = 9e-04
Identities = 37/126 (29%), Positives = 57/126 (45%), Gaps = 3/126 (2%)
Frame = +2
Query: 437 CNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTS-LAKLRWLTLENNQI-ETLPDT 610
C GL EIP + + + N +K IP S KLR + L NNQI E PD
Sbjct: 290 CRGKGLTEIPTNLPET--ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDA 347
Query: 611 MDRMTALVHCNLRNNRLEQFPSSILK-CKELMFLQLNSNQISSVPANLDTSLVPGLXMID 787
+ +L L N++ + P S+ + L L LN+N+I+ + + L L ++
Sbjct: 348 FQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDL-HNLNLLS 406
Query: 788 LRSNPI 805
L N +
Sbjct: 407 LYDNKL 412
Score = 30.7 bits (66), Expect = 6.8
Identities = 29/109 (26%), Positives = 47/109 (43%), Gaps = 3/109 (2%)
Frame = +2
Query: 482 LTQLDTFGARGNELKTIPEEM-TSLAKLRWLTLENNQIETLPDTMDR-MTALVHCNLRNN 655
L +L+ N L+ PE + AKL L L NQI+ +P R + + L N
Sbjct: 102 LKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYN 161
Query: 656 RLEQFPSSILKC-KELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSN 799
++ + ++L L LN+N I+ + + +P L L SN
Sbjct: 162 QISCIEDGAFRALRDLEVLTLNNNNITRLSV-ASFNHMPKLRTFRLHSN 209
>AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellular
slit protein Slit2 protein.
Length = 1521
Score = 54.0 bits (124), Expect = 6e-07
Identities = 39/125 (31%), Positives = 59/125 (47%), Gaps = 2/125 (1%)
Frame = +2
Query: 437 CNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPD-TM 613
C+ GLK +PK I + + GN+ +P+E+++ L + L NN+I TL + +
Sbjct: 732 CSNKGLKVLPKGIPR--DVTELYLDGNQFTLVPKELSNYKHLTLIDLSNNRISTLSNQSF 789
Query: 614 DRMTALVHCNLRNNRLEQFPSSILK-CKELMFLQLNSNQISSVPANLDTSLVPGLXMIDL 790
MT L+ L NRL P K L L L+ N IS VP L L + +
Sbjct: 790 SNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDL-SALSHLAI 848
Query: 791 RSNPI 805
+NP+
Sbjct: 849 GANPL 853
Score = 43.6 bits (98), Expect = 9e-04
Identities = 37/126 (29%), Positives = 57/126 (45%), Gaps = 3/126 (2%)
Frame = +2
Query: 437 CNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTS-LAKLRWLTLENNQI-ETLPDT 610
C GL EIP + + + N +K IP S KLR + L NNQI E PD
Sbjct: 286 CRGKGLTEIPTNLPET--ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDA 343
Query: 611 MDRMTALVHCNLRNNRLEQFPSSILK-CKELMFLQLNSNQISSVPANLDTSLVPGLXMID 787
+ +L L N++ + P S+ + L L LN+N+I+ + + L L ++
Sbjct: 344 FQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDL-HNLNLLS 402
Query: 788 LRSNPI 805
L N +
Sbjct: 403 LYDNKL 408
Score = 30.7 bits (66), Expect = 6.8
Identities = 29/109 (26%), Positives = 47/109 (43%), Gaps = 3/109 (2%)
Frame = +2
Query: 482 LTQLDTFGARGNELKTIPEEM-TSLAKLRWLTLENNQIETLPDTMDR-MTALVHCNLRNN 655
L +L+ N L+ PE + AKL L L NQI+ +P R + + L N
Sbjct: 102 LKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYN 161
Query: 656 RLEQFPSSILKC-KELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSN 799
++ + ++L L LN+N I+ + + +P L L SN
Sbjct: 162 QISCIEDGAFRALRDLEVLTLNNNNITRLSV-ASFNHMPKLRTFRLHSN 209
>AB033020-1|BAA86508.1| 575|Homo sapiens KIAA1194 protein protein.
Length = 575
Score = 54.0 bits (124), Expect = 6e-07
Identities = 28/66 (42%), Positives = 39/66 (59%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P++I L NLV L+LS N + L E+G++ L N L+ +P E+GKL QL T G
Sbjct: 85 PSDIAKLHNLVYLDLSSNKIRSLPAELGNMVSLRELHLNNNLLRVLPFELGKLFQLQTLG 144
Query: 506 ARGNEL 523
+GN L
Sbjct: 145 LKGNPL 150
Score = 50.4 bits (115), Expect = 8e-06
Identities = 29/100 (29%), Positives = 46/100 (46%)
Frame = +2
Query: 452 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 631
++ + + LT L N L IP ++ L L +L L +N+I +LP + M +L
Sbjct: 58 VRSLSASLWSLTHLTALHLSDNSLSRIPSDIAKLHNLVYLDLSSNKIRSLPAELGNMVSL 117
Query: 632 VHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANL 751
+L NN L P + K +L L L N ++ NL
Sbjct: 118 RELHLNNNLLRVLPFELGKLFQLQTLGLKGNPLTQDILNL 157
>AB023233-1|BAA76860.1| 793|Homo sapiens KIAA1016 protein protein.
Length = 793
Score = 54.0 bits (124), Expect = 6e-07
Identities = 30/100 (30%), Positives = 51/100 (51%)
Frame = +2
Query: 452 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 631
L E+P E+ L+ N ++ IPE + +L L +L L NQ+ LP + +
Sbjct: 174 LVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLPLK 233
Query: 632 VHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANL 751
V NN+L P I + K+LM L ++ N+I+++P +
Sbjct: 234 V-LIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQI 272
Score = 53.2 bits (122), Expect = 1e-06
Identities = 38/139 (27%), Positives = 69/139 (49%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P E+ + +L LNL +N + V+ I +L+ L +R L +P + L L
Sbjct: 178 PMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLP-LKVLI 236
Query: 506 ARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSIL 685
A N+L ++PEE+ L +L L + N+I LP + ++ +L N+R N L+ P ++
Sbjct: 237 ASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELV 296
Query: 686 KCKELMFLQLNSNQISSVP 742
+ F + N++ +P
Sbjct: 297 DLPLVKF-DFSCNKVLVIP 314
Score = 46.8 bits (106), Expect = 1e-04
Identities = 37/143 (25%), Positives = 64/143 (44%), Gaps = 1/143 (0%)
Frame = +2
Query: 341 NLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNE 520
+L + V +LS N L + E+ LE ++ IP+ I L L N+
Sbjct: 160 DLSDTVQADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQ 219
Query: 521 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 700
L +P + L L+ L NN++ +LP+ + ++ L+ ++ N + P I + K L
Sbjct: 220 LSALPACLCGLP-LKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSL 278
Query: 701 MFLQLNSNQISSVPANL-DTSLV 766
L + N + +P L D LV
Sbjct: 279 RELNVRRNYLKVLPQELVDLPLV 301
>AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein.
Length = 1529
Score = 54.0 bits (124), Expect = 6e-07
Identities = 39/125 (31%), Positives = 59/125 (47%), Gaps = 2/125 (1%)
Frame = +2
Query: 437 CNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPD-TM 613
C+ GLK +PK I + + GN+ +P+E+++ L + L NN+I TL + +
Sbjct: 740 CSNKGLKVLPKGIPR--DVTELYLDGNQFTLVPKELSNYKHLTLIDLSNNRISTLSNQSF 797
Query: 614 DRMTALVHCNLRNNRLEQFPSSILK-CKELMFLQLNSNQISSVPANLDTSLVPGLXMIDL 790
MT L+ L NRL P K L L L+ N IS VP L L + +
Sbjct: 798 SNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDL-SALSHLAI 856
Query: 791 RSNPI 805
+NP+
Sbjct: 857 GANPL 861
Score = 43.6 bits (98), Expect = 9e-04
Identities = 37/126 (29%), Positives = 57/126 (45%), Gaps = 3/126 (2%)
Frame = +2
Query: 437 CNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTS-LAKLRWLTLENNQI-ETLPDT 610
C GL EIP + + + N +K IP S KLR + L NNQI E PD
Sbjct: 286 CRGKGLTEIPTNLPET--ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDA 343
Query: 611 MDRMTALVHCNLRNNRLEQFPSSILK-CKELMFLQLNSNQISSVPANLDTSLVPGLXMID 787
+ +L L N++ + P S+ + L L LN+N+I+ + + L L ++
Sbjct: 344 FQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDL-HNLNLLS 402
Query: 788 LRSNPI 805
L N +
Sbjct: 403 LYDNKL 408
Score = 30.7 bits (66), Expect = 6.8
Identities = 29/109 (26%), Positives = 47/109 (43%), Gaps = 3/109 (2%)
Frame = +2
Query: 482 LTQLDTFGARGNELKTIPEEM-TSLAKLRWLTLENNQIETLPDTMDR-MTALVHCNLRNN 655
L +L+ N L+ PE + AKL L L NQI+ +P R + + L N
Sbjct: 102 LKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYN 161
Query: 656 RLEQFPSSILKC-KELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSN 799
++ + ++L L LN+N I+ + + +P L L SN
Sbjct: 162 QISCIEDGAFRALRDLEVLTLNNNNITRLSV-ASFNHMPKLRTFRLHSN 209
>BC146759-1|AAI46760.1| 1523|Homo sapiens slit homolog 3 (Drosophila)
protein.
Length = 1523
Score = 53.6 bits (123), Expect = 8e-07
Identities = 41/130 (31%), Positives = 60/130 (46%), Gaps = 3/130 (2%)
Frame = +2
Query: 437 CNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPD-TM 613
C+ GL+ +P+ + K + GN L +P E+++L L + L NN I L + T
Sbjct: 738 CSNKGLRALPRGMPK--DVTELYLEGNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTF 795
Query: 614 DRMTALVHCNLRNNRLEQFPSSILK-CKELMFLQLNSNQISSVPANLDTSLVPGLXMIDL 790
M+ L L NRL P + L L L+ N ISSVP L L + L
Sbjct: 796 SNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLT-SLSHLAL 854
Query: 791 RSNPI-CELS 817
+NP+ C+ S
Sbjct: 855 GTNPLHCDCS 864
>AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein.
Length = 1523
Score = 53.6 bits (123), Expect = 8e-07
Identities = 41/130 (31%), Positives = 60/130 (46%), Gaps = 3/130 (2%)
Frame = +2
Query: 437 CNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPD-TM 613
C+ GL+ +P+ + K + GN L +P E+++L L + L NN I L + T
Sbjct: 738 CSNKGLRALPRGMPK--DVTELYLEGNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTF 795
Query: 614 DRMTALVHCNLRNNRLEQFPSSILK-CKELMFLQLNSNQISSVPANLDTSLVPGLXMIDL 790
M+ L L NRL P + L L L+ N ISSVP L L + L
Sbjct: 796 SNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLT-SLSHLAL 854
Query: 791 RSNPI-CELS 817
+NP+ C+ S
Sbjct: 855 GTNPLHCDCS 864
>AF075240-1|AAD19336.1| 850|Homo sapiens SLIT1 protein protein.
Length = 850
Score = 53.6 bits (123), Expect = 8e-07
Identities = 41/130 (31%), Positives = 60/130 (46%), Gaps = 3/130 (2%)
Frame = +2
Query: 437 CNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPD-TM 613
C+ GL+ +P+ + K + GN L +P E+++L L + L NN I L + T
Sbjct: 165 CSNKGLRALPRGMPK--DVTELYLEGNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTF 222
Query: 614 DRMTALVHCNLRNNRLEQFPSSILK-CKELMFLQLNSNQISSVPANLDTSLVPGLXMIDL 790
M+ L L NRL P + L L L+ N ISSVP L L + L
Sbjct: 223 SNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLT-SLSHLAL 281
Query: 791 RSNPI-CELS 817
+NP+ C+ S
Sbjct: 282 GTNPLHCDCS 291
>AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein.
Length = 1523
Score = 53.6 bits (123), Expect = 8e-07
Identities = 41/130 (31%), Positives = 60/130 (46%), Gaps = 3/130 (2%)
Frame = +2
Query: 437 CNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPD-TM 613
C+ GL+ +P+ + K + GN L +P E+++L L + L NN I L + T
Sbjct: 738 CSNKGLRALPRGMPK--DVTELYLEGNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTF 795
Query: 614 DRMTALVHCNLRNNRLEQFPSSILK-CKELMFLQLNSNQISSVPANLDTSLVPGLXMIDL 790
M+ L L NRL P + L L L+ N ISSVP L L + L
Sbjct: 796 SNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLT-SLSHLAL 854
Query: 791 RSNPI-CELS 817
+NP+ C+ S
Sbjct: 855 GTNPLHCDCS 864
>AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein.
Length = 1559
Score = 53.6 bits (123), Expect = 8e-07
Identities = 41/130 (31%), Positives = 60/130 (46%), Gaps = 3/130 (2%)
Frame = +2
Query: 437 CNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPD-TM 613
C+ GL+ +P+ + K + GN L +P E+++L L + L NN I L + T
Sbjct: 774 CSNKGLRALPRGMPK--DVTELYLEGNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTF 831
Query: 614 DRMTALVHCNLRNNRLEQFPSSILK-CKELMFLQLNSNQISSVPANLDTSLVPGLXMIDL 790
M+ L L NRL P + L L L+ N ISSVP L L + L
Sbjct: 832 SNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLT-SLSHLAL 890
Query: 791 RSNPI-CELS 817
+NP+ C+ S
Sbjct: 891 GTNPLHCDCS 900
>BC095477-1|AAH95477.1| 522|Homo sapiens AMIGO2 protein protein.
Length = 522
Score = 52.4 bits (120), Expect = 2e-06
Identities = 57/173 (32%), Positives = 77/173 (44%), Gaps = 13/173 (7%)
Frame = +2
Query: 338 GNLKNLVN-LNLSYNPLNVLIPEIGDLE--KLEAFWCNRIGLKEIPKEIGKLT-QLDTFG 505
GNL L+ L+LSYN + +L E + KL + I T L
Sbjct: 64 GNLFRLIKRLDLSYNRIGLLDSEWIPVSFAKLNTLILRHNNITSISTGSFSTTPNLKCLD 123
Query: 506 ARGNELKTIPEEM-TSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQFPSS 679
N+LKT+ + L L L L NN I L P ++ L L N L QFP
Sbjct: 124 LSSNKLKTVKNAVFQELKVLEVLLLYNNHISYLDPSAFGGLSQLQKLYLSGNFLTQFPMD 183
Query: 680 I----LKCKELMFLQLNSNQISSVPANLDTSLVPG--LXMIDLRSNP-ICELS 817
+ K ELMFL ++ N+I S+P + +LVPG L I L NP +C+ S
Sbjct: 184 LYVGRFKLAELMFLDVSYNRIPSMPMH-HINLVPGKQLRGIYLHGNPFVCDCS 235
>BC047595-1|AAH47595.1| 522|Homo sapiens adhesion molecule with
Ig-like domain 2 protein.
Length = 522
Score = 52.4 bits (120), Expect = 2e-06
Identities = 57/173 (32%), Positives = 77/173 (44%), Gaps = 13/173 (7%)
Frame = +2
Query: 338 GNLKNLVN-LNLSYNPLNVLIPEIGDLE--KLEAFWCNRIGLKEIPKEIGKLT-QLDTFG 505
GNL L+ L+LSYN + +L E + KL + I T L
Sbjct: 64 GNLFRLIKRLDLSYNRIGLLDSEWIPVSFAKLNTLILRHNNITSISTGSFSTTPNLKCLD 123
Query: 506 ARGNELKTIPEEM-TSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQFPSS 679
N+LKT+ + L L L L NN I L P ++ L L N L QFP
Sbjct: 124 LSSNKLKTVKNAVFQELKVLEVLLLYNNHISYLDPSAFGGLSQLQKLYLSGNFLTQFPMD 183
Query: 680 I----LKCKELMFLQLNSNQISSVPANLDTSLVPG--LXMIDLRSNP-ICELS 817
+ K ELMFL ++ N+I S+P + +LVPG L I L NP +C+ S
Sbjct: 184 LYVGRFKLAELMFLDVSYNRIPSMPMH-HINLVPGKQLRGIYLHGNPFVCDCS 235
>AY454159-1|AAR83271.1| 522|Homo sapiens DEGA/AMIGO-2 precursor
protein.
Length = 522
Score = 52.4 bits (120), Expect = 2e-06
Identities = 57/173 (32%), Positives = 77/173 (44%), Gaps = 13/173 (7%)
Frame = +2
Query: 338 GNLKNLVN-LNLSYNPLNVLIPEIGDLE--KLEAFWCNRIGLKEIPKEIGKLT-QLDTFG 505
GNL L+ L+LSYN + +L E + KL + I T L
Sbjct: 64 GNLFRLIKRLDLSYNRIGLLDSEWIPVSFAKLNTLILRHNNITSISTGSFSTTPNLKCLD 123
Query: 506 ARGNELKTIPEEM-TSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQFPSS 679
N+LKT+ + L L L L NN I L P ++ L L N L QFP
Sbjct: 124 LSSNKLKTVKNAVFQELKVLEVLLLYNNHISYLDPSAFGGLSQLQKLYLSGNFLTQFPMD 183
Query: 680 I----LKCKELMFLQLNSNQISSVPANLDTSLVPG--LXMIDLRSNP-ICELS 817
+ K ELMFL ++ N+I S+P + +LVPG L I L NP +C+ S
Sbjct: 184 LYVGRFKLAELMFLDVSYNRIPSMPMH-HINLVPGKQLRGIYLHGNPFVCDCS 235
>AY237005-1|AAO48946.1| 522|Homo sapiens transmembrane protein
AMIGO2 protein.
Length = 522
Score = 52.4 bits (120), Expect = 2e-06
Identities = 57/173 (32%), Positives = 77/173 (44%), Gaps = 13/173 (7%)
Frame = +2
Query: 338 GNLKNLVN-LNLSYNPLNVLIPEIGDLE--KLEAFWCNRIGLKEIPKEIGKLT-QLDTFG 505
GNL L+ L+LSYN + +L E + KL + I T L
Sbjct: 64 GNLFRLIKRLDLSYNRIGLLDSEWIPVSFAKLNTLILRHNNITSISTGSFSTTPNLKCLD 123
Query: 506 ARGNELKTIPEEM-TSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQFPSS 679
N+LKT+ + L L L L NN I L P ++ L L N L QFP
Sbjct: 124 LSSNKLKTVKNAVFQELKVLEVLLLYNNHISYLDPSAFGGLSQLQKLYLSGNFLTQFPMD 183
Query: 680 I----LKCKELMFLQLNSNQISSVPANLDTSLVPG--LXMIDLRSNP-ICELS 817
+ K ELMFL ++ N+I S+P + +LVPG L I L NP +C+ S
Sbjct: 184 LYVGRFKLAELMFLDVSYNRIPSMPMH-HINLVPGKQLRGIYLHGNPFVCDCS 235
>AB080610-1|BAC81189.1| 522|Homo sapiens alivin 1 protein.
Length = 522
Score = 52.4 bits (120), Expect = 2e-06
Identities = 57/173 (32%), Positives = 77/173 (44%), Gaps = 13/173 (7%)
Frame = +2
Query: 338 GNLKNLVN-LNLSYNPLNVLIPEIGDLE--KLEAFWCNRIGLKEIPKEIGKLT-QLDTFG 505
GNL L+ L+LSYN + +L E + KL + I T L
Sbjct: 64 GNLFRLIKRLDLSYNRIGLLDSEWIPVSFAKLNTLILRHNNITSISTGSFSTTPNLKCLD 123
Query: 506 ARGNELKTIPEEM-TSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQFPSS 679
N+LKT+ + L L L L NN I L P ++ L L N L QFP
Sbjct: 124 LSSNKLKTVKNAVFQELKVLEVLLLYNNHISYLDPSAFGGLSQLQKLYLSGNFLTQFPMD 183
Query: 680 I----LKCKELMFLQLNSNQISSVPANLDTSLVPG--LXMIDLRSNP-ICELS 817
+ K ELMFL ++ N+I S+P + +LVPG L I L NP +C+ S
Sbjct: 184 LYVGRFKLAELMFLDVSYNRIPSMPMH-HINLVPGKQLRGIYLHGNPFVCDCS 235
>U41344-1|AAC18782.1| 382|Homo sapiens prolargin protein.
Length = 382
Score = 52.0 bits (119), Expect = 3e-06
Identities = 34/130 (26%), Positives = 69/130 (53%), Gaps = 2/130 (1%)
Frame = +2
Query: 428 AFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP-EEMTSLAKLRWLTLENNQIETLP 604
A +C+ L+++P ++ L + N + +P E + LRW+ L+NN+I +
Sbjct: 86 ALYCDSRNLRKVPVIPPRIHYLYL---QNNFITELPVESFQNATGLRWINLDNNRIRKID 142
Query: 605 D-TMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXM 781
++++ LV + N+LE+ PS++ + L L+L+ N IS +P + + L L +
Sbjct: 143 QRVLEKLPGLVFLYMEKNQLEEVPSAL--PRNLEQLRLSQNHISRIPPGVFSKL-ENLLL 199
Query: 782 IDLRSNPICE 811
+DL+ N + +
Sbjct: 200 LDLQHNRLSD 209
Score = 39.5 bits (88), Expect = 0.015
Identities = 35/142 (24%), Positives = 66/142 (46%), Gaps = 3/142 (2%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGK-LTQLDTF 502
P LKNL+ LNL++N L + P + + + + ++ IP K L
Sbjct: 214 PDTFHGLKNLMQLNLAHNILRKMPPRVP--TAIHQLYLDSNKIETIPNGYFKSFPNLAFI 271
Query: 503 GARGNEL--KTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 676
N+L + +P+ +++ L L L +N+I ++P +R L H L NN +E+
Sbjct: 272 RLNYNKLTDRGLPKNSFNISNLLVLHLSHNRISSVPAINNR---LEHLYLNNNSIEKING 328
Query: 677 SILKCKELMFLQLNSNQISSVP 742
+ + +L+ S+ + +VP
Sbjct: 329 TQICPNDLVAFHDFSSDLENVP 350
Score = 38.3 bits (85), Expect = 0.034
Identities = 39/140 (27%), Positives = 61/140 (43%), Gaps = 7/140 (5%)
Frame = +2
Query: 347 KNLVNLNLSYNPLNVLIPEI-GDLEKLEAFWCNRIGLKE---IPKEIGKLTQLDTFGARG 514
+NL L LS N ++ + P + LE L L + P L L
Sbjct: 171 RNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAH 230
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDR-MTALVHCNLRNNRLEQ--FPSSIL 685
N L+ +P + + + L L++N+IET+P+ + L L N+L P +
Sbjct: 231 NILRKMPPRVPTA--IHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSF 288
Query: 686 KCKELMFLQLNSNQISSVPA 745
L+ L L+ N+ISSVPA
Sbjct: 289 NISNLLVLHLSHNRISSVPA 308
Score = 35.5 bits (78), Expect = 0.24
Identities = 52/212 (24%), Positives = 86/212 (40%), Gaps = 7/212 (3%)
Frame = +2
Query: 215 VEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVL 394
+ +LYL N I+ PVE N L +NL N + +
Sbjct: 104 IHYLYLQNNFITELPVE----------------------SFQNATGLRWINLDNNRIRKI 141
Query: 395 IPEIGDLEKLEA---FWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTS-LAKL 562
+ LEKL + + L+E+P + + L+ N + IP + S L L
Sbjct: 142 DQRV--LEKLPGLVFLYMEKNQLEEVPSALPR--NLEQLRLSQNHISRIPPGVFSKLENL 197
Query: 563 RWLTLENNQIET---LPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQIS 733
L L++N++ PDT + L+ NL +N L + P + + L L+SN+I
Sbjct: 198 LLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTA--IHQLYLDSNKIE 255
Query: 734 SVPANLDTSLVPGLXMIDLRSNPICELSHPEH 829
++P S P L I L N + + P++
Sbjct: 256 TIPNGYFKSF-PNLAFIRLNYNKLTDRGLPKN 286
>U29089-1|AAC50230.1| 382|Homo sapiens proline- arginine-rich end
leucine-rich repeat protein protein.
Length = 382
Score = 52.0 bits (119), Expect = 3e-06
Identities = 34/130 (26%), Positives = 69/130 (53%), Gaps = 2/130 (1%)
Frame = +2
Query: 428 AFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP-EEMTSLAKLRWLTLENNQIETLP 604
A +C+ L+++P ++ L + N + +P E + LRW+ L+NN+I +
Sbjct: 86 ALYCDSRNLRKVPVIPPRIHYLYL---QNNFITELPVESFQNATGLRWINLDNNRIRKID 142
Query: 605 D-TMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXM 781
++++ LV + N+LE+ PS++ + L L+L+ N IS +P + + L L +
Sbjct: 143 QRVLEKLPGLVFLYMEKNQLEEVPSAL--PRNLEQLRLSQNHISRIPPGVFSKL-ENLLL 199
Query: 782 IDLRSNPICE 811
+DL+ N + +
Sbjct: 200 LDLQHNRLSD 209
Score = 39.5 bits (88), Expect = 0.015
Identities = 35/142 (24%), Positives = 66/142 (46%), Gaps = 3/142 (2%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGK-LTQLDTF 502
P LKNL+ LNL++N L + P + + + + ++ IP K L
Sbjct: 214 PDTFHGLKNLMQLNLAHNILRKMPPRVP--TAIHQLYLDSNKIETIPNGYFKSFPNLAFI 271
Query: 503 GARGNEL--KTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 676
N+L + +P+ +++ L L L +N+I ++P +R L H L NN +E+
Sbjct: 272 RLNYNKLTDRGLPKNSFNISNLLVLHLSHNRISSVPAINNR---LEHLYLNNNSIEKING 328
Query: 677 SILKCKELMFLQLNSNQISSVP 742
+ + +L+ S+ + +VP
Sbjct: 329 TQICPNDLVAFHDFSSDLENVP 350
Score = 38.3 bits (85), Expect = 0.034
Identities = 39/140 (27%), Positives = 61/140 (43%), Gaps = 7/140 (5%)
Frame = +2
Query: 347 KNLVNLNLSYNPLNVLIPEI-GDLEKLEAFWCNRIGLKE---IPKEIGKLTQLDTFGARG 514
+NL L LS N ++ + P + LE L L + P L L
Sbjct: 171 RNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAH 230
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDR-MTALVHCNLRNNRLEQ--FPSSIL 685
N L+ +P + + + L L++N+IET+P+ + L L N+L P +
Sbjct: 231 NILRKMPPRVPTA--IHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSF 288
Query: 686 KCKELMFLQLNSNQISSVPA 745
L+ L L+ N+ISSVPA
Sbjct: 289 NISNLLVLHLSHNRISSVPA 308
Score = 35.5 bits (78), Expect = 0.24
Identities = 52/212 (24%), Positives = 86/212 (40%), Gaps = 7/212 (3%)
Frame = +2
Query: 215 VEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVL 394
+ +LYL N I+ PVE N L +NL N + +
Sbjct: 104 IHYLYLQNNFITELPVE----------------------SFQNATGLRWINLDNNRIRKI 141
Query: 395 IPEIGDLEKLEA---FWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTS-LAKL 562
+ LEKL + + L+E+P + + L+ N + IP + S L L
Sbjct: 142 DQRV--LEKLPGLVFLYMEKNQLEEVPSALPR--NLEQLRLSQNHISRIPPGVFSKLENL 197
Query: 563 RWLTLENNQIET---LPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQIS 733
L L++N++ PDT + L+ NL +N L + P + + L L+SN+I
Sbjct: 198 LLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTA--IHQLYLDSNKIE 255
Query: 734 SVPANLDTSLVPGLXMIDLRSNPICELSHPEH 829
++P S P L I L N + + P++
Sbjct: 256 TIPNGYFKSF-PNLAFIRLNYNKLTDRGLPKN 286
>CR542270-1|CAG47066.1| 382|Homo sapiens PRELP protein.
Length = 382
Score = 52.0 bits (119), Expect = 3e-06
Identities = 34/130 (26%), Positives = 69/130 (53%), Gaps = 2/130 (1%)
Frame = +2
Query: 428 AFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP-EEMTSLAKLRWLTLENNQIETLP 604
A +C+ L+++P ++ L + N + +P E + LRW+ L+NN+I +
Sbjct: 86 ALYCDSRNLRKVPVIPPRIHYLYL---QNNFITELPVESFQNATGLRWINLDNNRIRKID 142
Query: 605 D-TMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXM 781
++++ LV + N+LE+ PS++ + L L+L+ N IS +P + + L L +
Sbjct: 143 QRVLEKLPGLVFLYMEKNQLEEVPSAL--PRNLEQLRLSQNHISRIPPGVFSKL-ENLLL 199
Query: 782 IDLRSNPICE 811
+DL+ N + +
Sbjct: 200 LDLQHNRLSD 209
Score = 39.5 bits (88), Expect = 0.015
Identities = 35/142 (24%), Positives = 66/142 (46%), Gaps = 3/142 (2%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGK-LTQLDTF 502
P LKNL+ LNL++N L + P + + + + ++ IP K L
Sbjct: 214 PDTFHGLKNLMQLNLAHNILRKMPPRVP--TAIHQLYLDSNKIETIPNGYFKSFPNLAFI 271
Query: 503 GARGNEL--KTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 676
N+L + +P+ +++ L L L +N+I ++P +R L H L NN +E+
Sbjct: 272 RLNYNKLTDRGLPKNSFNISNLLVLHLSHNRISSVPAINNR---LEHLYLNNNSIEKING 328
Query: 677 SILKCKELMFLQLNSNQISSVP 742
+ + +L+ S+ + +VP
Sbjct: 329 TQICPNDLVAFHDFSSDLENVP 350
Score = 38.3 bits (85), Expect = 0.034
Identities = 39/140 (27%), Positives = 61/140 (43%), Gaps = 7/140 (5%)
Frame = +2
Query: 347 KNLVNLNLSYNPLNVLIPEI-GDLEKLEAFWCNRIGLKE---IPKEIGKLTQLDTFGARG 514
+NL L LS N ++ + P + LE L L + P L L
Sbjct: 171 RNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAH 230
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDR-MTALVHCNLRNNRLEQ--FPSSIL 685
N L+ +P + + + L L++N+IET+P+ + L L N+L P +
Sbjct: 231 NILRKMPPRVPTA--IHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSF 288
Query: 686 KCKELMFLQLNSNQISSVPA 745
L+ L L+ N+ISSVPA
Sbjct: 289 NISNLLVLHLSHNRISSVPA 308
Score = 35.5 bits (78), Expect = 0.24
Identities = 52/212 (24%), Positives = 86/212 (40%), Gaps = 7/212 (3%)
Frame = +2
Query: 215 VEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVL 394
+ +LYL N I+ PVE N L +NL N + +
Sbjct: 104 IHYLYLQNNFITELPVE----------------------SFQNATGLRWINLDNNRIRKI 141
Query: 395 IPEIGDLEKLEA---FWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTS-LAKL 562
+ LEKL + + L+E+P + + L+ N + IP + S L L
Sbjct: 142 DQRV--LEKLPGLVFLYMEKNQLEEVPSALPR--NLEQLRLSQNHISRIPPGVFSKLENL 197
Query: 563 RWLTLENNQIET---LPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQIS 733
L L++N++ PDT + L+ NL +N L + P + + L L+SN+I
Sbjct: 198 LLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTA--IHQLYLDSNKIE 255
Query: 734 SVPANLDTSLVPGLXMIDLRSNPICELSHPEH 829
++P S P L I L N + + P++
Sbjct: 256 TIPNGYFKSF-PNLAFIRLNYNKLTDRGLPKN 286
>CR541787-1|CAG46586.1| 382|Homo sapiens PRELP protein.
Length = 382
Score = 52.0 bits (119), Expect = 3e-06
Identities = 34/130 (26%), Positives = 69/130 (53%), Gaps = 2/130 (1%)
Frame = +2
Query: 428 AFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP-EEMTSLAKLRWLTLENNQIETLP 604
A +C+ L+++P ++ L + N + +P E + LRW+ L+NN+I +
Sbjct: 86 ALYCDSRNLRKVPVIPPRIHYLYL---QSNFITELPVESFQNATGLRWINLDNNRIRKID 142
Query: 605 D-TMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXM 781
++++ LV + N+LE+ PS++ + L L+L+ N IS +P + + L L +
Sbjct: 143 QRVLEKLPGLVFLYMEKNQLEEVPSAL--PRNLEQLRLSQNHISRIPPGVFSKL-ENLLL 199
Query: 782 IDLRSNPICE 811
+DL+ N + +
Sbjct: 200 LDLQHNRLSD 209
Score = 39.5 bits (88), Expect = 0.015
Identities = 35/142 (24%), Positives = 66/142 (46%), Gaps = 3/142 (2%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGK-LTQLDTF 502
P LKNL+ LNL++N L + P + + + + ++ IP K L
Sbjct: 214 PDTFHGLKNLMQLNLAHNILRKMPPRVP--TAIHQLYLDSNKIETIPNGYFKSFPNLAFI 271
Query: 503 GARGNEL--KTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 676
N+L + +P+ +++ L L L +N+I ++P +R L H L NN +E+
Sbjct: 272 RLNYNKLTDRGLPKNSFNISNLLVLHLSHNRISSVPAINNR---LEHLYLNNNSIEKING 328
Query: 677 SILKCKELMFLQLNSNQISSVP 742
+ + +L+ S+ + +VP
Sbjct: 329 TQICPNDLVAFHDFSSDLENVP 350
Score = 38.3 bits (85), Expect = 0.034
Identities = 39/140 (27%), Positives = 61/140 (43%), Gaps = 7/140 (5%)
Frame = +2
Query: 347 KNLVNLNLSYNPLNVLIPEI-GDLEKLEAFWCNRIGLKE---IPKEIGKLTQLDTFGARG 514
+NL L LS N ++ + P + LE L L + P L L
Sbjct: 171 RNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAH 230
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDR-MTALVHCNLRNNRLEQ--FPSSIL 685
N L+ +P + + + L L++N+IET+P+ + L L N+L P +
Sbjct: 231 NILRKMPPRVPTA--IHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSF 288
Query: 686 KCKELMFLQLNSNQISSVPA 745
L+ L L+ N+ISSVPA
Sbjct: 289 NISNLLVLHLSHNRISSVPA 308
Score = 35.5 bits (78), Expect = 0.24
Identities = 52/212 (24%), Positives = 86/212 (40%), Gaps = 7/212 (3%)
Frame = +2
Query: 215 VEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVL 394
+ +LYL N I+ PVE N L +NL N + +
Sbjct: 104 IHYLYLQSNFITELPVE----------------------SFQNATGLRWINLDNNRIRKI 141
Query: 395 IPEIGDLEKLEA---FWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTS-LAKL 562
+ LEKL + + L+E+P + + L+ N + IP + S L L
Sbjct: 142 DQRV--LEKLPGLVFLYMEKNQLEEVPSALPR--NLEQLRLSQNHISRIPPGVFSKLENL 197
Query: 563 RWLTLENNQIET---LPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQIS 733
L L++N++ PDT + L+ NL +N L + P + + L L+SN+I
Sbjct: 198 LLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTA--IHQLYLDSNKIE 255
Query: 734 SVPANLDTSLVPGLXMIDLRSNPICELSHPEH 829
++P S P L I L N + + P++
Sbjct: 256 TIPNGYFKSF-PNLAFIRLNYNKLTDRGLPKN 286
>BC032498-1|AAH32498.1| 382|Homo sapiens proline/arginine-rich end
leucine-rich repeat protein protein.
Length = 382
Score = 52.0 bits (119), Expect = 3e-06
Identities = 34/130 (26%), Positives = 69/130 (53%), Gaps = 2/130 (1%)
Frame = +2
Query: 428 AFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP-EEMTSLAKLRWLTLENNQIETLP 604
A +C+ L+++P ++ L + N + +P E + LRW+ L+NN+I +
Sbjct: 86 ALYCDSRNLRKVPVIPPRIHYLYL---QNNFITELPVESFQNATGLRWINLDNNRIRKID 142
Query: 605 D-TMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXM 781
++++ LV + N+LE+ PS++ + L L+L+ N IS +P + + L L +
Sbjct: 143 QRVLEKLPGLVFLYMEKNQLEEVPSAL--PRNLEQLRLSQNHISRIPPGVFSKL-ENLLL 199
Query: 782 IDLRSNPICE 811
+DL+ N + +
Sbjct: 200 LDLQHNRLSD 209
Score = 39.5 bits (88), Expect = 0.015
Identities = 35/142 (24%), Positives = 66/142 (46%), Gaps = 3/142 (2%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGK-LTQLDTF 502
P LKNL+ LNL++N L + P + + + + ++ IP K L
Sbjct: 214 PDTFHGLKNLMQLNLAHNILRKMPPRVP--TAIHQLYLDSNKIETIPNGYFKSFPNLAFI 271
Query: 503 GARGNEL--KTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 676
N+L + +P+ +++ L L L +N+I ++P +R L H L NN +E+
Sbjct: 272 RLNYNKLTDRGLPKNSFNISNLLVLHLSHNRISSVPAINNR---LEHLYLNNNSIEKING 328
Query: 677 SILKCKELMFLQLNSNQISSVP 742
+ + +L+ S+ + +VP
Sbjct: 329 TQICPNDLVAFHDFSSDLENVP 350
Score = 38.3 bits (85), Expect = 0.034
Identities = 39/140 (27%), Positives = 61/140 (43%), Gaps = 7/140 (5%)
Frame = +2
Query: 347 KNLVNLNLSYNPLNVLIPEI-GDLEKLEAFWCNRIGLKE---IPKEIGKLTQLDTFGARG 514
+NL L LS N ++ + P + LE L L + P L L
Sbjct: 171 RNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAH 230
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDR-MTALVHCNLRNNRLEQ--FPSSIL 685
N L+ +P + + + L L++N+IET+P+ + L L N+L P +
Sbjct: 231 NILRKMPPRVPTA--IHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSF 288
Query: 686 KCKELMFLQLNSNQISSVPA 745
L+ L L+ N+ISSVPA
Sbjct: 289 NISNLLVLHLSHNRISSVPA 308
Score = 35.5 bits (78), Expect = 0.24
Identities = 52/212 (24%), Positives = 86/212 (40%), Gaps = 7/212 (3%)
Frame = +2
Query: 215 VEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVL 394
+ +LYL N I+ PVE N L +NL N + +
Sbjct: 104 IHYLYLQNNFITELPVE----------------------SFQNATGLRWINLDNNRIRKI 141
Query: 395 IPEIGDLEKLEA---FWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTS-LAKL 562
+ LEKL + + L+E+P + + L+ N + IP + S L L
Sbjct: 142 DQRV--LEKLPGLVFLYMEKNQLEEVPSALPR--NLEQLRLSQNHISRIPPGVFSKLENL 197
Query: 563 RWLTLENNQIET---LPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQIS 733
L L++N++ PDT + L+ NL +N L + P + + L L+SN+I
Sbjct: 198 LLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTA--IHQLYLDSNKIE 255
Query: 734 SVPANLDTSLVPGLXMIDLRSNPICELSHPEH 829
++P S P L I L N + + P++
Sbjct: 256 TIPNGYFKSF-PNLAFIRLNYNKLTDRGLPKN 286
>AL391817-1|CAI17033.1| 382|Homo sapiens proline/arginine-rich end
leucine-rich repeat protein protein.
Length = 382
Score = 52.0 bits (119), Expect = 3e-06
Identities = 34/130 (26%), Positives = 69/130 (53%), Gaps = 2/130 (1%)
Frame = +2
Query: 428 AFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP-EEMTSLAKLRWLTLENNQIETLP 604
A +C+ L+++P ++ L + N + +P E + LRW+ L+NN+I +
Sbjct: 86 ALYCDSRNLRKVPVIPPRIHYLYL---QNNFITELPVESFQNATGLRWINLDNNRIRKID 142
Query: 605 D-TMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXM 781
++++ LV + N+LE+ PS++ + L L+L+ N IS +P + + L L +
Sbjct: 143 QRVLEKLPGLVFLYMEKNQLEEVPSAL--PRNLEQLRLSQNHISRIPPGVFSKL-ENLLL 199
Query: 782 IDLRSNPICE 811
+DL+ N + +
Sbjct: 200 LDLQHNRLSD 209
Score = 39.5 bits (88), Expect = 0.015
Identities = 35/142 (24%), Positives = 66/142 (46%), Gaps = 3/142 (2%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGK-LTQLDTF 502
P LKNL+ LNL++N L + P + + + + ++ IP K L
Sbjct: 214 PDTFHGLKNLMQLNLAHNILRKMPPRVP--TAIHQLYLDSNKIETIPNGYFKSFPNLAFI 271
Query: 503 GARGNEL--KTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 676
N+L + +P+ +++ L L L +N+I ++P +R L H L NN +E+
Sbjct: 272 RLNYNKLTDRGLPKNSFNISNLLVLHLSHNRISSVPAINNR---LEHLYLNNNSIEKING 328
Query: 677 SILKCKELMFLQLNSNQISSVP 742
+ + +L+ S+ + +VP
Sbjct: 329 TQICPNDLVAFHDFSSDLENVP 350
Score = 38.3 bits (85), Expect = 0.034
Identities = 39/140 (27%), Positives = 61/140 (43%), Gaps = 7/140 (5%)
Frame = +2
Query: 347 KNLVNLNLSYNPLNVLIPEI-GDLEKLEAFWCNRIGLKE---IPKEIGKLTQLDTFGARG 514
+NL L LS N ++ + P + LE L L + P L L
Sbjct: 171 RNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAH 230
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDR-MTALVHCNLRNNRLEQ--FPSSIL 685
N L+ +P + + + L L++N+IET+P+ + L L N+L P +
Sbjct: 231 NILRKMPPRVPTA--IHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSF 288
Query: 686 KCKELMFLQLNSNQISSVPA 745
L+ L L+ N+ISSVPA
Sbjct: 289 NISNLLVLHLSHNRISSVPA 308
Score = 35.5 bits (78), Expect = 0.24
Identities = 52/212 (24%), Positives = 86/212 (40%), Gaps = 7/212 (3%)
Frame = +2
Query: 215 VEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVL 394
+ +LYL N I+ PVE N L +NL N + +
Sbjct: 104 IHYLYLQNNFITELPVE----------------------SFQNATGLRWINLDNNRIRKI 141
Query: 395 IPEIGDLEKLEA---FWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTS-LAKL 562
+ LEKL + + L+E+P + + L+ N + IP + S L L
Sbjct: 142 DQRV--LEKLPGLVFLYMEKNQLEEVPSALPR--NLEQLRLSQNHISRIPPGVFSKLENL 197
Query: 563 RWLTLENNQIET---LPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQIS 733
L L++N++ PDT + L+ NL +N L + P + + L L+SN+I
Sbjct: 198 LLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTA--IHQLYLDSNKIE 255
Query: 734 SVPANLDTSLVPGLXMIDLRSNPICELSHPEH 829
++P S P L I L N + + P++
Sbjct: 256 TIPNGYFKSF-PNLAFIRLNYNKLTDRGLPKN 286
>AK127177-1|BAC86870.1| 279|Homo sapiens protein ( Homo sapiens
cDNA FLJ45242 fis, clone BRCOC2006639. ).
Length = 279
Score = 51.6 bits (118), Expect = 3e-06
Identities = 25/100 (25%), Positives = 55/100 (55%), Gaps = 1/100 (1%)
Frame = +2
Query: 470 EIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLR 649
E+G L +L T N L T+PE + L++LT++ N++ +P + ++ +L ++
Sbjct: 41 EVGDLKELQTLDISTNRLLTLPERLHMCLSLQYLTVDRNRLWYVPRHLCQLPSLNELSMA 100
Query: 650 NNRLEQFPSSILKCKELMFLQLNSN-QISSVPANLDTSLV 766
NRL P + + +EL ++ +++N + +P+ L ++
Sbjct: 101 GNRLAFLPLDLGRSRELQYVYVDNNIHLKGLPSYLYNKVI 140
Score = 40.7 bits (91), Expect = 0.006
Identities = 25/92 (27%), Positives = 48/92 (52%), Gaps = 1/92 (1%)
Frame = +2
Query: 332 EIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGAR 511
E+G+LK L L++S N L L + L+ +R L +P+ + +L L+
Sbjct: 41 EVGDLKELQTLDISTNRLLTLPERLHMCLSLQYLTVDRNRLWYVPRHLCQLPSLNELSMA 100
Query: 512 GNELKTIPEEMTSLAKLRWLTLENN-QIETLP 604
GN L +P ++ +L+++ ++NN ++ LP
Sbjct: 101 GNRLAFLPLDLGRSRELQYVYVDNNIHLKGLP 132
>BC051738-1|AAH51738.1| 696|Homo sapiens SLIT and NTRK-like family,
member 1 protein.
Length = 696
Score = 50.8 bits (116), Expect = 6e-06
Identities = 38/120 (31%), Positives = 58/120 (48%), Gaps = 4/120 (3%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIP-EIGDLEKLEAFWCNRIGLKEIPKE--IGKLTQLD 496
P E N N V+L++ N L+ ++P L+ ++ N +K K+ +G L L+
Sbjct: 75 PNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLG-LDDLE 133
Query: 497 TFGARGNELKTI-PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 673
A N L+ I P L KL L L +N I TLP + + + H +LR NRL+ P
Sbjct: 134 YLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLKTLP 193
Score = 41.1 bits (92), Expect = 0.005
Identities = 30/98 (30%), Positives = 42/98 (42%), Gaps = 2/98 (2%)
Frame = +2
Query: 515 NELKTIP-EEMTSLAKLRWLTLENNQIET-LPDTMDRMTALVHCNLRNNRLEQFPSSILK 688
N L T+ E+ L L +L +E N I+ LP T + M L L NN L P +
Sbjct: 433 NYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFA 492
Query: 689 CKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNP 802
L L L++N +P + + IDL NP
Sbjct: 493 GVSLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNP 530
Score = 36.3 bits (80), Expect = 0.14
Identities = 34/152 (22%), Positives = 61/152 (40%), Gaps = 4/152 (2%)
Frame = +2
Query: 359 NLNLSYNPLNVLIP-EIGDLEKLEAFWCNRIGLKEI-PKEIGKLTQLDTFGARGNELKTI 532
+L L N L L P E + + GL EI P L + N++K+
Sbjct: 62 HLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSF 121
Query: 533 PEE-MTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMF 706
++ L L +L + N + + P + L L +N + P+++ + +
Sbjct: 122 RKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITH 181
Query: 707 LQLNSNQISSVPANLDTSLVPGLXMIDLRSNP 802
L L N++ ++P +PG+ I L NP
Sbjct: 182 LDLRGNRLKTLPYEEVLEQIPGIAEILLEDNP 213
>AY358289-1|AAQ88656.1| 696|Homo sapiens LLWI233 protein.
Length = 696
Score = 50.8 bits (116), Expect = 6e-06
Identities = 38/120 (31%), Positives = 58/120 (48%), Gaps = 4/120 (3%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIP-EIGDLEKLEAFWCNRIGLKEIPKE--IGKLTQLD 496
P E N N V+L++ N L+ ++P L+ ++ N +K K+ +G L L+
Sbjct: 75 PNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLG-LDDLE 133
Query: 497 TFGARGNELKTI-PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 673
A N L+ I P L KL L L +N I TLP + + + H +LR NRL+ P
Sbjct: 134 YLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLKTLP 193
Score = 41.1 bits (92), Expect = 0.005
Identities = 30/98 (30%), Positives = 42/98 (42%), Gaps = 2/98 (2%)
Frame = +2
Query: 515 NELKTIP-EEMTSLAKLRWLTLENNQIET-LPDTMDRMTALVHCNLRNNRLEQFPSSILK 688
N L T+ E+ L L +L +E N I+ LP T + M L L NN L P +
Sbjct: 433 NYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFA 492
Query: 689 CKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNP 802
L L L++N +P + + IDL NP
Sbjct: 493 GVSLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNP 530
Score = 36.3 bits (80), Expect = 0.14
Identities = 34/152 (22%), Positives = 61/152 (40%), Gaps = 4/152 (2%)
Frame = +2
Query: 359 NLNLSYNPLNVLIP-EIGDLEKLEAFWCNRIGLKEI-PKEIGKLTQLDTFGARGNELKTI 532
+L L N L L P E + + GL EI P L + N++K+
Sbjct: 62 HLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSF 121
Query: 533 PEE-MTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMF 706
++ L L +L + N + + P + L L +N + P+++ + +
Sbjct: 122 RKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITH 181
Query: 707 LQLNSNQISSVPANLDTSLVPGLXMIDLRSNP 802
L L N++ ++P +PG+ I L NP
Sbjct: 182 LDLRGNRLKTLPYEEVLEQIPGIAEILLEDNP 213
>AL355481-1|CAC37488.1| 696|Homo sapiens SLIT and NTRK-like family,
member 1 protein.
Length = 696
Score = 50.8 bits (116), Expect = 6e-06
Identities = 38/120 (31%), Positives = 58/120 (48%), Gaps = 4/120 (3%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIP-EIGDLEKLEAFWCNRIGLKEIPKE--IGKLTQLD 496
P E N N V+L++ N L+ ++P L+ ++ N +K K+ +G L L+
Sbjct: 75 PNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLG-LDDLE 133
Query: 497 TFGARGNELKTI-PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 673
A N L+ I P L KL L L +N I TLP + + + H +LR NRL+ P
Sbjct: 134 YLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLKTLP 193
Score = 41.1 bits (92), Expect = 0.005
Identities = 30/98 (30%), Positives = 42/98 (42%), Gaps = 2/98 (2%)
Frame = +2
Query: 515 NELKTIP-EEMTSLAKLRWLTLENNQIET-LPDTMDRMTALVHCNLRNNRLEQFPSSILK 688
N L T+ E+ L L +L +E N I+ LP T + M L L NN L P +
Sbjct: 433 NYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFA 492
Query: 689 CKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNP 802
L L L++N +P + + IDL NP
Sbjct: 493 GVSLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNP 530
Score = 36.3 bits (80), Expect = 0.14
Identities = 34/152 (22%), Positives = 61/152 (40%), Gaps = 4/152 (2%)
Frame = +2
Query: 359 NLNLSYNPLNVLIP-EIGDLEKLEAFWCNRIGLKEI-PKEIGKLTQLDTFGARGNELKTI 532
+L L N L L P E + + GL EI P L + N++K+
Sbjct: 62 HLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSF 121
Query: 533 PEE-MTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMF 706
++ L L +L + N + + P + L L +N + P+++ + +
Sbjct: 122 RKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITH 181
Query: 707 LQLNSNQISSVPANLDTSLVPGLXMIDLRSNP 802
L L N++ ++P +PG+ I L NP
Sbjct: 182 LDLRGNRLKTLPYEEVLEQIPGIAEILLEDNP 213
>AL159161-1|CAI17102.1| 754|Homo sapiens relaxin/insulin-like
family peptide receptor 2 protein.
Length = 754
Score = 50.8 bits (116), Expect = 6e-06
Identities = 39/104 (37%), Positives = 53/104 (50%), Gaps = 3/104 (2%)
Frame = +2
Query: 515 NELKTIPEEM-TSLAKLRWLTLENNQIETLPDTM-DRMTALVHCNLRNNRLEQFPSS-IL 685
N + I + + T L L +L++ NN +E LP M +M L +L NR++ +S L
Sbjct: 219 NPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFL 278
Query: 686 KCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELS 817
C L L L NQI VP +SL L +DL SN I ELS
Sbjct: 279 SCDSLTVLFLPRNQIGFVPEKTFSSL-KNLGELDLSSNTITELS 321
>AL138708-1|CAH73785.1| 754|Homo sapiens relaxin/insulin-like
family peptide receptor 2 protein.
Length = 754
Score = 50.8 bits (116), Expect = 6e-06
Identities = 39/104 (37%), Positives = 53/104 (50%), Gaps = 3/104 (2%)
Frame = +2
Query: 515 NELKTIPEEM-TSLAKLRWLTLENNQIETLPDTM-DRMTALVHCNLRNNRLEQFPSS-IL 685
N + I + + T L L +L++ NN +E LP M +M L +L NR++ +S L
Sbjct: 219 NPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFL 278
Query: 686 KCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELS 817
C L L L NQI VP +SL L +DL SN I ELS
Sbjct: 279 SCDSLTVLFLPRNQIGFVPEKTFSSL-KNLGELDLSSNTITELS 321
>AF453828-1|AAL73946.1| 754|Homo sapiens G protein-coupled receptor
affecting testicular descent protein.
Length = 754
Score = 50.8 bits (116), Expect = 6e-06
Identities = 39/104 (37%), Positives = 53/104 (50%), Gaps = 3/104 (2%)
Frame = +2
Query: 515 NELKTIPEEM-TSLAKLRWLTLENNQIETLPDTM-DRMTALVHCNLRNNRLEQFPSS-IL 685
N + I + + T L L +L++ NN +E LP M +M L +L NR++ +S L
Sbjct: 219 NPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFL 278
Query: 686 KCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELS 817
C L L L NQI VP +SL L +DL SN I ELS
Sbjct: 279 SCDSLTVLFLPRNQIGFVPEKTFSSL-KNLGELDLSSNTITELS 321
>AF403384-1|AAL69324.2| 754|Homo sapiens LGR8 protein.
Length = 754
Score = 50.8 bits (116), Expect = 6e-06
Identities = 39/104 (37%), Positives = 53/104 (50%), Gaps = 3/104 (2%)
Frame = +2
Query: 515 NELKTIPEEM-TSLAKLRWLTLENNQIETLPDTM-DRMTALVHCNLRNNRLEQFPSS-IL 685
N + I + + T L L +L++ NN +E LP M +M L +L NR++ +S L
Sbjct: 219 NPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFL 278
Query: 686 KCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELS 817
C L L L NQI VP +SL L +DL SN I ELS
Sbjct: 279 SCDSLTVLFLPRNQIGFVPEKTFSSL-KNLGELDLSSNTITELS 321
>AB067497-1|BAB67803.1| 760|Homo sapiens KIAA1910 protein protein.
Length = 760
Score = 50.8 bits (116), Expect = 6e-06
Identities = 38/120 (31%), Positives = 58/120 (48%), Gaps = 4/120 (3%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIP-EIGDLEKLEAFWCNRIGLKEIPKE--IGKLTQLD 496
P E N N V+L++ N L+ ++P L+ ++ N +K K+ +G L L+
Sbjct: 139 PNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLG-LDDLE 197
Query: 497 TFGARGNELKTI-PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 673
A N L+ I P L KL L L +N I TLP + + + H +LR NRL+ P
Sbjct: 198 YLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLKTLP 257
Score = 41.1 bits (92), Expect = 0.005
Identities = 30/98 (30%), Positives = 42/98 (42%), Gaps = 2/98 (2%)
Frame = +2
Query: 515 NELKTIP-EEMTSLAKLRWLTLENNQIET-LPDTMDRMTALVHCNLRNNRLEQFPSSILK 688
N L T+ E+ L L +L +E N I+ LP T + M L L NN L P +
Sbjct: 497 NYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFA 556
Query: 689 CKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNP 802
L L L++N +P + + IDL NP
Sbjct: 557 GVSLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNP 594
Score = 36.3 bits (80), Expect = 0.14
Identities = 34/152 (22%), Positives = 61/152 (40%), Gaps = 4/152 (2%)
Frame = +2
Query: 359 NLNLSYNPLNVLIP-EIGDLEKLEAFWCNRIGLKEI-PKEIGKLTQLDTFGARGNELKTI 532
+L L N L L P E + + GL EI P L + N++K+
Sbjct: 126 HLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSF 185
Query: 533 PEE-MTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMF 706
++ L L +L + N + + P + L L +N + P+++ + +
Sbjct: 186 RKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITH 245
Query: 707 LQLNSNQISSVPANLDTSLVPGLXMIDLRSNP 802
L L N++ ++P +PG+ I L NP
Sbjct: 246 LDLRGNRLKTLPYEEVLEQIPGIAEILLEDNP 277
>Y19205-1|CAC80724.1| 845|Homo sapiens SLITL1 protein.
Length = 845
Score = 50.4 bits (115), Expect = 8e-06
Identities = 36/109 (33%), Positives = 48/109 (44%), Gaps = 2/109 (1%)
Frame = +2
Query: 482 LTQLDTFGARGNELKTI-PEEMTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNN 655
LT L GN L+ + P L L++L LE N I+ + P T D + L L NN
Sbjct: 422 LTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNN 481
Query: 656 RLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNP 802
L P +I L L L +N S +P +P IDL+ NP
Sbjct: 482 LLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENP 530
Score = 44.4 bits (100), Expect = 5e-04
Identities = 46/160 (28%), Positives = 72/160 (45%), Gaps = 6/160 (3%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLN-VLIPEIGDLEKLEAFWCNRIGLKEIPKE--IGKLTQLD 496
P E N N V L+L N L + L+ L+ N L+ + ++ +G L L+
Sbjct: 79 PNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLG-LESLE 137
Query: 497 TFGARGNELKTIPE-EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 673
A N + I + L KL+ L L +N + +LP + R L H +LR NRL+ P
Sbjct: 138 YLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMP 197
Query: 674 -SSILK-CKELMFLQLNSNQISSVPANLDTSLVPGLXMID 787
+ +L+ +M +QL N P N L+P +D
Sbjct: 198 FAGVLEHIGGIMEIQLEEN-----PWNCTCDLLPLKAWLD 232
>U96769-1|AAC13410.1| 359|Homo sapiens chondroadherin protein.
Length = 359
Score = 50.4 bits (115), Expect = 8e-06
Identities = 41/116 (35%), Positives = 57/116 (49%), Gaps = 5/116 (4%)
Frame = +2
Query: 347 KNLVNLNLSYNPLNVLIP-EIGDLEKLEAFWCNRIGLKEIPKE-IGKLTQLDTFGARGNE 520
K+L L LS N L+ L P + D+E L F +R L P + KL ++ N
Sbjct: 171 KDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNP 230
Query: 521 LKTIPEE-MTSLAK-LRWLTLENNQIETLPD-TMDRMTALVHCNLRNNRLEQFPSS 679
LK+IP+ S + L L L+N +E D +T L H +L NNRL Q PS+
Sbjct: 231 LKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQLPSN 286
Score = 38.3 bits (85), Expect = 0.034
Identities = 34/128 (26%), Positives = 60/128 (46%), Gaps = 2/128 (1%)
Frame = +2
Query: 437 CNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQI-ETLPDTM 613
C+++GL++IPK K L+ R N ++ L L L++ QI E
Sbjct: 38 CDKVGLQKIPKVSEKTKLLNL--QRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAF 95
Query: 614 DRMTALVHCNLRNNRLEQFPSSIL-KCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDL 790
+ L++ L +N + + EL +L L+ N+++ +P L + LV L ++ L
Sbjct: 96 RGLKQLIYLYLSHNDIRVVRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLV-NLFILQL 154
Query: 791 RSNPICEL 814
+N I EL
Sbjct: 155 NNNKIREL 162
>BC113012-1|AAI13013.1| 845|Homo sapiens SLIT and NTRK-like family,
member 2 protein.
Length = 845
Score = 50.4 bits (115), Expect = 8e-06
Identities = 36/109 (33%), Positives = 48/109 (44%), Gaps = 2/109 (1%)
Frame = +2
Query: 482 LTQLDTFGARGNELKTI-PEEMTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNN 655
LT L GN L+ + P L L++L LE N I+ + P T D + L L NN
Sbjct: 422 LTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNN 481
Query: 656 RLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNP 802
L P +I L L L +N S +P +P IDL+ NP
Sbjct: 482 LLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENP 530
Score = 44.4 bits (100), Expect = 5e-04
Identities = 46/160 (28%), Positives = 72/160 (45%), Gaps = 6/160 (3%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLN-VLIPEIGDLEKLEAFWCNRIGLKEIPKE--IGKLTQLD 496
P E N N V L+L N L + L+ L+ N L+ + ++ +G L L+
Sbjct: 79 PNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLG-LESLE 137
Query: 497 TFGARGNELKTIPE-EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 673
A N + I + L KL+ L L +N + +LP + R L H +LR NRL+ P
Sbjct: 138 YLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMP 197
Query: 674 -SSILK-CKELMFLQLNSNQISSVPANLDTSLVPGLXMID 787
+ +L+ +M +QL N P N L+P +D
Sbjct: 198 FAGVLEHIGGIMEIQLEEN-----PWNCTCDLLPLKAWLD 232
>BC113011-1|AAI13012.1| 845|Homo sapiens SLIT and NTRK-like family,
member 2 protein.
Length = 845
Score = 50.4 bits (115), Expect = 8e-06
Identities = 36/109 (33%), Positives = 48/109 (44%), Gaps = 2/109 (1%)
Frame = +2
Query: 482 LTQLDTFGARGNELKTI-PEEMTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNN 655
LT L GN L+ + P L L++L LE N I+ + P T D + L L NN
Sbjct: 422 LTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNN 481
Query: 656 RLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNP 802
L P +I L L L +N S +P +P IDL+ NP
Sbjct: 482 LLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENP 530
Score = 44.4 bits (100), Expect = 5e-04
Identities = 46/160 (28%), Positives = 72/160 (45%), Gaps = 6/160 (3%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLN-VLIPEIGDLEKLEAFWCNRIGLKEIPKE--IGKLTQLD 496
P E N N V L+L N L + L+ L+ N L+ + ++ +G L L+
Sbjct: 79 PNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLG-LESLE 137
Query: 497 TFGARGNELKTIPE-EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 673
A N + I + L KL+ L L +N + +LP + R L H +LR NRL+ P
Sbjct: 138 YLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMP 197
Query: 674 -SSILK-CKELMFLQLNSNQISSVPANLDTSLVPGLXMID 787
+ +L+ +M +QL N P N L+P +D
Sbjct: 198 FAGVLEHIGGIMEIQLEEN-----PWNCTCDLLPLKAWLD 232
>BC073974-1|AAH73974.1| 359|Homo sapiens chondroadherin protein.
Length = 359
Score = 50.4 bits (115), Expect = 8e-06
Identities = 41/116 (35%), Positives = 57/116 (49%), Gaps = 5/116 (4%)
Frame = +2
Query: 347 KNLVNLNLSYNPLNVLIP-EIGDLEKLEAFWCNRIGLKEIPKE-IGKLTQLDTFGARGNE 520
K+L L LS N L+ L P + D+E L F +R L P + KL ++ N
Sbjct: 171 KDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNP 230
Query: 521 LKTIPEE-MTSLAK-LRWLTLENNQIETLPD-TMDRMTALVHCNLRNNRLEQFPSS 679
LK+IP+ S + L L L+N +E D +T L H +L NNRL Q PS+
Sbjct: 231 LKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQLPSN 286
Score = 38.7 bits (86), Expect = 0.026
Identities = 34/128 (26%), Positives = 60/128 (46%), Gaps = 2/128 (1%)
Frame = +2
Query: 437 CNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQI-ETLPDTM 613
C+++GL++IPK K L+ R N ++ L L L++ QI E
Sbjct: 38 CDKVGLQKIPKVSEKTKLLNL--QRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAF 95
Query: 614 DRMTALVHCNLRNNRLEQFPSSIL-KCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDL 790
+ L++ L +N + + EL +L L+ N+++ +P L + LV L ++ L
Sbjct: 96 RGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLV-NLFILQL 154
Query: 791 RSNPICEL 814
+N I EL
Sbjct: 155 NNNKIREL 162
>BC036360-1|AAH36360.1| 359|Homo sapiens chondroadherin protein.
Length = 359
Score = 50.4 bits (115), Expect = 8e-06
Identities = 41/116 (35%), Positives = 57/116 (49%), Gaps = 5/116 (4%)
Frame = +2
Query: 347 KNLVNLNLSYNPLNVLIP-EIGDLEKLEAFWCNRIGLKEIPKE-IGKLTQLDTFGARGNE 520
K+L L LS N L+ L P + D+E L F +R L P + KL ++ N
Sbjct: 171 KDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNP 230
Query: 521 LKTIPEE-MTSLAK-LRWLTLENNQIETLPD-TMDRMTALVHCNLRNNRLEQFPSS 679
LK+IP+ S + L L L+N +E D +T L H +L NNRL Q PS+
Sbjct: 231 LKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQLPSN 286
Score = 38.7 bits (86), Expect = 0.026
Identities = 34/128 (26%), Positives = 60/128 (46%), Gaps = 2/128 (1%)
Frame = +2
Query: 437 CNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQI-ETLPDTM 613
C+++GL++IPK K L+ R N ++ L L L++ QI E
Sbjct: 38 CDKVGLQKIPKVSEKTKLLNL--QRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAF 95
Query: 614 DRMTALVHCNLRNNRLEQFPSSIL-KCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDL 790
+ L++ L +N + + EL +L L+ N+++ +P L + LV L ++ L
Sbjct: 96 RGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLV-NLFILQL 154
Query: 791 RSNPICEL 814
+N I EL
Sbjct: 155 NNNKIREL 162
>AY358828-1|AAQ89187.1| 733|Homo sapiens LSGV9197 protein.
Length = 733
Score = 50.4 bits (115), Expect = 8e-06
Identities = 36/109 (33%), Positives = 48/109 (44%), Gaps = 2/109 (1%)
Frame = +2
Query: 482 LTQLDTFGARGNELKTI-PEEMTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNN 655
LT L GN L+ + P L L++L LE N I+ + P T D + L L NN
Sbjct: 422 LTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNN 481
Query: 656 RLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNP 802
L P +I L L L +N S +P +P IDL+ NP
Sbjct: 482 LLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENP 530
Score = 44.4 bits (100), Expect = 5e-04
Identities = 46/160 (28%), Positives = 72/160 (45%), Gaps = 6/160 (3%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLN-VLIPEIGDLEKLEAFWCNRIGLKEIPKE--IGKLTQLD 496
P E N N V L+L N L + L+ L+ N L+ + ++ +G L L+
Sbjct: 79 PNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLG-LESLE 137
Query: 497 TFGARGNELKTIPE-EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 673
A N + I + L KL+ L L +N + +LP + R L H +LR NRL+ P
Sbjct: 138 YLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMP 197
Query: 674 -SSILK-CKELMFLQLNSNQISSVPANLDTSLVPGLXMID 787
+ +L+ +M +QL N P N L+P +D
Sbjct: 198 FAGVLEHIGGIMEIQLEEN-----PWNCTCDLLPLKAWLD 232
>AL109653-2|CAC18888.1| 845|Homo sapiens SLIT and NTRK-like family,
member 2 protein.
Length = 845
Score = 50.4 bits (115), Expect = 8e-06
Identities = 36/109 (33%), Positives = 48/109 (44%), Gaps = 2/109 (1%)
Frame = +2
Query: 482 LTQLDTFGARGNELKTI-PEEMTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNN 655
LT L GN L+ + P L L++L LE N I+ + P T D + L L NN
Sbjct: 422 LTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNN 481
Query: 656 RLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNP 802
L P +I L L L +N S +P +P IDL+ NP
Sbjct: 482 LLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENP 530
Score = 44.4 bits (100), Expect = 5e-04
Identities = 46/160 (28%), Positives = 72/160 (45%), Gaps = 6/160 (3%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLN-VLIPEIGDLEKLEAFWCNRIGLKEIPKE--IGKLTQLD 496
P E N N V L+L N L + L+ L+ N L+ + ++ +G L L+
Sbjct: 79 PNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLG-LESLE 137
Query: 497 TFGARGNELKTIPE-EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 673
A N + I + L KL+ L L +N + +LP + R L H +LR NRL+ P
Sbjct: 138 YLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMP 197
Query: 674 -SSILK-CKELMFLQLNSNQISSVPANLDTSLVPGLXMID 787
+ +L+ +M +QL N P N L+P +D
Sbjct: 198 FAGVLEHIGGIMEIQLEEN-----PWNCTCDLLPLKAWLD 232
>AL109653-1|CAI41645.1| 724|Homo sapiens SLIT and NTRK-like family,
member 2 protein.
Length = 724
Score = 50.4 bits (115), Expect = 8e-06
Identities = 36/109 (33%), Positives = 48/109 (44%), Gaps = 2/109 (1%)
Frame = +2
Query: 482 LTQLDTFGARGNELKTI-PEEMTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNN 655
LT L GN L+ + P L L++L LE N I+ + P T D + L L NN
Sbjct: 422 LTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNN 481
Query: 656 RLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNP 802
L P +I L L L +N S +P +P IDL+ NP
Sbjct: 482 LLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENP 530
Score = 44.4 bits (100), Expect = 5e-04
Identities = 46/160 (28%), Positives = 72/160 (45%), Gaps = 6/160 (3%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLN-VLIPEIGDLEKLEAFWCNRIGLKEIPKE--IGKLTQLD 496
P E N N V L+L N L + L+ L+ N L+ + ++ +G L L+
Sbjct: 79 PNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLG-LESLE 137
Query: 497 TFGARGNELKTIPE-EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 673
A N + I + L KL+ L L +N + +LP + R L H +LR NRL+ P
Sbjct: 138 YLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMP 197
Query: 674 -SSILK-CKELMFLQLNSNQISSVPANLDTSLVPGLXMID 787
+ +L+ +M +QL N P N L+P +D
Sbjct: 198 FAGVLEHIGGIMEIQLEEN-----PWNCTCDLLPLKAWLD 232
>AK091015-1|BAC03566.1| 724|Homo sapiens protein ( Homo sapiens
cDNA FLJ33696 fis, clone BRAWH2003964, weakly similar to
SLIT PROTEIN PRECURSOR. ).
Length = 724
Score = 50.4 bits (115), Expect = 8e-06
Identities = 36/109 (33%), Positives = 48/109 (44%), Gaps = 2/109 (1%)
Frame = +2
Query: 482 LTQLDTFGARGNELKTI-PEEMTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNN 655
LT L GN L+ + P L L++L LE N I+ + P T D + L L NN
Sbjct: 422 LTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNN 481
Query: 656 RLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNP 802
L P +I L L L +N S +P +P IDL+ NP
Sbjct: 482 LLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENP 530
Score = 44.4 bits (100), Expect = 5e-04
Identities = 46/160 (28%), Positives = 72/160 (45%), Gaps = 6/160 (3%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLN-VLIPEIGDLEKLEAFWCNRIGLKEIPKE--IGKLTQLD 496
P E N N V L+L N L + L+ L+ N L+ + ++ +G L L+
Sbjct: 79 PNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLG-LESLE 137
Query: 497 TFGARGNELKTIPE-EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 673
A N + I + L KL+ L L +N + +LP + R L H +LR NRL+ P
Sbjct: 138 YLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMP 197
Query: 674 -SSILK-CKELMFLQLNSNQISSVPANLDTSLVPGLXMID 787
+ +L+ +M +QL N P N L+P +D
Sbjct: 198 FAGVLEHIGGIMEIQLEEN-----PWNCTCDLLPLKAWLD 232
>AF371328-1|AAK51556.1| 359|Homo sapiens chondroadherin protein.
Length = 359
Score = 50.4 bits (115), Expect = 8e-06
Identities = 41/116 (35%), Positives = 57/116 (49%), Gaps = 5/116 (4%)
Frame = +2
Query: 347 KNLVNLNLSYNPLNVLIP-EIGDLEKLEAFWCNRIGLKEIPKE-IGKLTQLDTFGARGNE 520
K+L L LS N L+ L P + D+E L F +R L P + KL ++ N
Sbjct: 171 KDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNP 230
Query: 521 LKTIPEE-MTSLAK-LRWLTLENNQIETLPD-TMDRMTALVHCNLRNNRLEQFPSS 679
LK+IP+ S + L L L+N +E D +T L H +L NNRL Q PS+
Sbjct: 231 LKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQLPSN 286
Score = 38.7 bits (86), Expect = 0.026
Identities = 34/128 (26%), Positives = 60/128 (46%), Gaps = 2/128 (1%)
Frame = +2
Query: 437 CNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQI-ETLPDTM 613
C+++GL++IPK K L+ R N ++ L L L++ QI E
Sbjct: 38 CDKVGLQKIPKVSEKTKLLNL--QRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAF 95
Query: 614 DRMTALVHCNLRNNRLEQFPSSIL-KCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDL 790
+ L++ L +N + + EL +L L+ N+++ +P L + LV L ++ L
Sbjct: 96 RGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLV-NLFILQL 154
Query: 791 RSNPICEL 814
+N I EL
Sbjct: 155 NNNKIREL 162
>AB058757-1|BAB47483.1| 572|Homo sapiens KIAA1854 protein protein.
Length = 572
Score = 50.4 bits (115), Expect = 8e-06
Identities = 36/109 (33%), Positives = 48/109 (44%), Gaps = 2/109 (1%)
Frame = +2
Query: 482 LTQLDTFGARGNELKTI-PEEMTSLAKLRWLTLENNQIETL-PDTMDRMTALVHCNLRNN 655
LT L GN L+ + P L L++L LE N I+ + P T D + L L NN
Sbjct: 428 LTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNN 487
Query: 656 RLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNP 802
L P +I L L L +N S +P +P IDL+ NP
Sbjct: 488 LLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENP 536
Score = 44.4 bits (100), Expect = 5e-04
Identities = 46/160 (28%), Positives = 72/160 (45%), Gaps = 6/160 (3%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLN-VLIPEIGDLEKLEAFWCNRIGLKEIPKE--IGKLTQLD 496
P E N N V L+L N L + L+ L+ N L+ + ++ +G L L+
Sbjct: 85 PNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLG-LESLE 143
Query: 497 TFGARGNELKTIPE-EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 673
A N + I + L KL+ L L +N + +LP + R L H +LR NRL+ P
Sbjct: 144 YLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMP 203
Query: 674 -SSILK-CKELMFLQLNSNQISSVPANLDTSLVPGLXMID 787
+ +L+ +M +QL N P N L+P +D
Sbjct: 204 FAGVLEHIGGIMEIQLEEN-----PWNCTCDLLPLKAWLD 238
>AL391728-3|CAH73693.1| 217|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 217
Score = 50.0 bits (114), Expect = 1e-05
Identities = 36/147 (24%), Positives = 66/147 (44%), Gaps = 1/147 (0%)
Frame = +2
Query: 362 LNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE 538
L+ S+ L + E+ + E+ LE + + ++E+PK++ L N+L +P
Sbjct: 65 LDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPT 124
Query: 539 EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLN 718
+ SL L+ L + N ++ P+ + L N + + P + L L LN
Sbjct: 125 TIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLN 184
Query: 719 SNQISSVPANLDTSLVPGLXMIDLRSN 799
+ +PAN LV L +++LR N
Sbjct: 185 DAFLEFLPANFG-RLVK-LRILELREN 209
Score = 47.6 bits (108), Expect = 6e-05
Identities = 33/127 (25%), Positives = 49/127 (38%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ +I E+P L+ C + L + N +S P P
Sbjct: 89 LYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPEN 148
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
I K L + S NP++ L L L + N L+ +P G+L +L R
Sbjct: 149 IKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRE 208
Query: 515 NELKTIP 535
N LKT+P
Sbjct: 209 NHLKTLP 215
Score = 44.4 bits (100), Expect = 5e-04
Identities = 33/140 (23%), Positives = 56/140 (40%), Gaps = 1/140 (0%)
Frame = +2
Query: 326 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
P E+ N + L L L N + L ++ + + L L +P I L L
Sbjct: 76 PKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKEL 135
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 682
N ++ PE + L + N I LPD ++ L L + LE P++
Sbjct: 136 DISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANF 195
Query: 683 LKCKELMFLQLNSNQISSVP 742
+ +L L+L N + ++P
Sbjct: 196 GRLVKLRILELRENHLKTLP 215
Score = 42.7 bits (96), Expect = 0.002
Identities = 33/131 (25%), Positives = 51/131 (38%)
Frame = +2
Query: 215 VEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVL 394
+E LYL N+I P + PT I +L NL L++S N +
Sbjct: 86 LEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEF 145
Query: 395 IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLT 574
I + L + + ++P +L L L+ +P L KLR L
Sbjct: 146 PENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILE 205
Query: 575 LENNQIETLPD 607
L N ++TLP+
Sbjct: 206 LRENHLKTLPN 216
>AL359894-1|CAH73131.1| 217|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 217
Score = 50.0 bits (114), Expect = 1e-05
Identities = 36/147 (24%), Positives = 66/147 (44%), Gaps = 1/147 (0%)
Frame = +2
Query: 362 LNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE 538
L+ S+ L + E+ + E+ LE + + ++E+PK++ L N+L +P
Sbjct: 65 LDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPT 124
Query: 539 EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLN 718
+ SL L+ L + N ++ P+ + L N + + P + L L LN
Sbjct: 125 TIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLN 184
Query: 719 SNQISSVPANLDTSLVPGLXMIDLRSN 799
+ +PAN LV L +++LR N
Sbjct: 185 DAFLEFLPANFG-RLVK-LRILELREN 209
Score = 47.6 bits (108), Expect = 6e-05
Identities = 33/127 (25%), Positives = 49/127 (38%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ +I E+P L+ C + L + N +S P P
Sbjct: 89 LYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPEN 148
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
I K L + S NP++ L L L + N L+ +P G+L +L R
Sbjct: 149 IKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRE 208
Query: 515 NELKTIP 535
N LKT+P
Sbjct: 209 NHLKTLP 215
Score = 44.4 bits (100), Expect = 5e-04
Identities = 33/140 (23%), Positives = 56/140 (40%), Gaps = 1/140 (0%)
Frame = +2
Query: 326 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
P E+ N + L L L N + L ++ + + L L +P I L L
Sbjct: 76 PKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKEL 135
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 682
N ++ PE + L + N I LPD ++ L L + LE P++
Sbjct: 136 DISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANF 195
Query: 683 LKCKELMFLQLNSNQISSVP 742
+ +L L+L N + ++P
Sbjct: 196 GRLVKLRILELRENHLKTLP 215
Score = 42.7 bits (96), Expect = 0.002
Identities = 33/131 (25%), Positives = 51/131 (38%)
Frame = +2
Query: 215 VEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVL 394
+E LYL N+I P + PT I +L NL L++S N +
Sbjct: 86 LEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEF 145
Query: 395 IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLT 574
I + L + + ++P +L L L+ +P L KLR L
Sbjct: 146 PENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILE 205
Query: 575 LENNQIETLPD 607
L N ++TLP+
Sbjct: 206 LRENHLKTLPN 216
>AL359412-3|CAH74020.1| 217|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 217
Score = 50.0 bits (114), Expect = 1e-05
Identities = 36/147 (24%), Positives = 66/147 (44%), Gaps = 1/147 (0%)
Frame = +2
Query: 362 LNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE 538
L+ S+ L + E+ + E+ LE + + ++E+PK++ L N+L +P
Sbjct: 65 LDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPT 124
Query: 539 EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLN 718
+ SL L+ L + N ++ P+ + L N + + P + L L LN
Sbjct: 125 TIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLN 184
Query: 719 SNQISSVPANLDTSLVPGLXMIDLRSN 799
+ +PAN LV L +++LR N
Sbjct: 185 DAFLEFLPANFG-RLVK-LRILELREN 209
Score = 47.6 bits (108), Expect = 6e-05
Identities = 33/127 (25%), Positives = 49/127 (38%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ +I E+P L+ C + L + N +S P P
Sbjct: 89 LYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPEN 148
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
I K L + S NP++ L L L + N L+ +P G+L +L R
Sbjct: 149 IKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRE 208
Query: 515 NELKTIP 535
N LKT+P
Sbjct: 209 NHLKTLP 215
Score = 44.4 bits (100), Expect = 5e-04
Identities = 33/140 (23%), Positives = 56/140 (40%), Gaps = 1/140 (0%)
Frame = +2
Query: 326 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
P E+ N + L L L N + L ++ + + L L +P I L L
Sbjct: 76 PKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKEL 135
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 682
N ++ PE + L + N I LPD ++ L L + LE P++
Sbjct: 136 DISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANF 195
Query: 683 LKCKELMFLQLNSNQISSVP 742
+ +L L+L N + ++P
Sbjct: 196 GRLVKLRILELRENHLKTLP 215
Score = 42.7 bits (96), Expect = 0.002
Identities = 33/131 (25%), Positives = 51/131 (38%)
Frame = +2
Query: 215 VEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVL 394
+E LYL N+I P + PT I +L NL L++S N +
Sbjct: 86 LEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEF 145
Query: 395 IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLT 574
I + L + + ++P +L L L+ +P L KLR L
Sbjct: 146 PENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILE 205
Query: 575 LENNQIETLPD 607
L N ++TLP+
Sbjct: 206 LRENHLKTLPN 216
>AL117353-2|CAI23424.1| 217|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 217
Score = 50.0 bits (114), Expect = 1e-05
Identities = 36/147 (24%), Positives = 66/147 (44%), Gaps = 1/147 (0%)
Frame = +2
Query: 362 LNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE 538
L+ S+ L + E+ + E+ LE + + ++E+PK++ L N+L +P
Sbjct: 65 LDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPT 124
Query: 539 EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLN 718
+ SL L+ L + N ++ P+ + L N + + P + L L LN
Sbjct: 125 TIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLN 184
Query: 719 SNQISSVPANLDTSLVPGLXMIDLRSN 799
+ +PAN LV L +++LR N
Sbjct: 185 DAFLEFLPANFG-RLVK-LRILELREN 209
Score = 47.6 bits (108), Expect = 6e-05
Identities = 33/127 (25%), Positives = 49/127 (38%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ +I E+P L+ C + L + N +S P P
Sbjct: 89 LYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPEN 148
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
I K L + S NP++ L L L + N L+ +P G+L +L R
Sbjct: 149 IKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRE 208
Query: 515 NELKTIP 535
N LKT+P
Sbjct: 209 NHLKTLP 215
Score = 44.4 bits (100), Expect = 5e-04
Identities = 33/140 (23%), Positives = 56/140 (40%), Gaps = 1/140 (0%)
Frame = +2
Query: 326 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
P E+ N + L L L N + L ++ + + L L +P I L L
Sbjct: 76 PKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKEL 135
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 682
N ++ PE + L + N I LPD ++ L L + LE P++
Sbjct: 136 DISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANF 195
Query: 683 LKCKELMFLQLNSNQISSVP 742
+ +L L+L N + ++P
Sbjct: 196 GRLVKLRILELRENHLKTLP 215
Score = 42.7 bits (96), Expect = 0.002
Identities = 33/131 (25%), Positives = 51/131 (38%)
Frame = +2
Query: 215 VEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVL 394
+E LYL N+I P + PT I +L NL L++S N +
Sbjct: 86 LEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEF 145
Query: 395 IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLT 574
I + L + + ++P +L L L+ +P L KLR L
Sbjct: 146 PENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILE 205
Query: 575 LENNQIETLPD 607
L N ++TLP+
Sbjct: 206 LRENHLKTLPN 216
>AF498274-1|AAP06801.1| 217|Homo sapiens densin-180 like protein
protein.
Length = 217
Score = 50.0 bits (114), Expect = 1e-05
Identities = 36/147 (24%), Positives = 66/147 (44%), Gaps = 1/147 (0%)
Frame = +2
Query: 362 LNLSYNPLNVLIPEIGDLEK-LEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPE 538
L+ S+ L + E+ + E+ LE + + ++E+PK++ L N+L +P
Sbjct: 65 LDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPT 124
Query: 539 EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLN 718
+ SL L+ L + N ++ P+ + L N + + P + L L LN
Sbjct: 125 TIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLN 184
Query: 719 SNQISSVPANLDTSLVPGLXMIDLRSN 799
+ +PAN LV L +++LR N
Sbjct: 185 DAFLEFLPANFG-RLVK-LRILELREN 209
Score = 47.6 bits (108), Expect = 6e-05
Identities = 33/127 (25%), Positives = 49/127 (38%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L L+ +I E+P L+ C + L + N +S P P
Sbjct: 89 LYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPEN 148
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARG 514
I K L + S NP++ L L L + N L+ +P G+L +L R
Sbjct: 149 IKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRE 208
Query: 515 NELKTIP 535
N LKT+P
Sbjct: 209 NHLKTLP 215
Score = 44.4 bits (100), Expect = 5e-04
Identities = 33/140 (23%), Positives = 56/140 (40%), Gaps = 1/140 (0%)
Frame = +2
Query: 326 PTEIGNL-KNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
P E+ N + L L L N + L ++ + + L L +P I L L
Sbjct: 76 PKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKEL 135
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSI 682
N ++ PE + L + N I LPD ++ L L + LE P++
Sbjct: 136 DISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANF 195
Query: 683 LKCKELMFLQLNSNQISSVP 742
+ +L L+L N + ++P
Sbjct: 196 GRLVKLRILELRENHLKTLP 215
Score = 42.7 bits (96), Expect = 0.002
Identities = 33/131 (25%), Positives = 51/131 (38%)
Frame = +2
Query: 215 VEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNLSYNPLNVL 394
+E LYL N+I P + PT I +L NL L++S N +
Sbjct: 86 LEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEF 145
Query: 395 IPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLT 574
I + L + + ++P +L L L+ +P L KLR L
Sbjct: 146 PENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILE 205
Query: 575 LENNQIETLPD 607
L N ++TLP+
Sbjct: 206 LRENHLKTLPN 216
>BC040986-1|AAH40986.1| 837|Homo sapiens SLIT and NTRK-like family,
member 4 protein.
Length = 837
Score = 49.6 bits (113), Expect = 1e-05
Identities = 43/155 (27%), Positives = 69/155 (44%), Gaps = 4/155 (2%)
Frame = +2
Query: 350 NLVNLNLSYNPL-NVLIPEIGDLEKLEAFWCNRIGLKEIPKEI-GKLTQLDTFGARGNEL 523
N L+++ N + +V + + D E L+ + I ++ LT L GN++
Sbjct: 378 NAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQI 437
Query: 524 KTI-PEEMTSLAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQFPSSILKCKE 697
+ + PE + L L++L LE N I+ + T D M L L NN L+ P I
Sbjct: 438 ERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAP 497
Query: 698 LMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNP 802
L L L +N+ +P + + L IDL NP
Sbjct: 498 LARLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGNP 532
Score = 43.6 bits (98), Expect = 9e-04
Identities = 43/165 (26%), Positives = 73/165 (44%), Gaps = 8/165 (4%)
Frame = +2
Query: 203 TCLEVEH-LYLHKNKISIF---PVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNL 370
+C+ VE+ LY++ K+S++ ++ P N + V+L+L
Sbjct: 31 SCVSVENVLYVNCEKVSVYRPNQLKPPWSNFYHLNFQNNFLNILYPNTFLNFSHAVSLHL 90
Query: 371 SYNPL-NVLIPEIGDLEKLEAFWCNRIGLKEIPKE--IGKLTQLDTFGARGNELKTIPE- 538
N L N+ L L+ N LK + + +G + L+ A N +K I
Sbjct: 91 GNNKLQNIEGGAFLGLSALKQLHLNNNELKILRADTFLG-IENLEYLQADYNLIKYIERG 149
Query: 539 EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 673
L KL+ L L +N I LPD + R +L H ++R NR+++ P
Sbjct: 150 AFNKLHKLKVLILNDNLISFLPDNIFRFASLTHLDIRGNRIQKLP 194
>AL713693-1|CAD28493.1| 689|Homo sapiens hypothetical protein
protein.
Length = 689
Score = 49.6 bits (113), Expect = 1e-05
Identities = 43/155 (27%), Positives = 69/155 (44%), Gaps = 4/155 (2%)
Frame = +2
Query: 350 NLVNLNLSYNPL-NVLIPEIGDLEKLEAFWCNRIGLKEIPKEI-GKLTQLDTFGARGNEL 523
N L+++ N + +V + + D E L+ + I ++ LT L GN++
Sbjct: 230 NAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQI 289
Query: 524 KTI-PEEMTSLAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQFPSSILKCKE 697
+ + PE + L L++L LE N I+ + T D M L L NN L+ P I
Sbjct: 290 ERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAP 349
Query: 698 LMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNP 802
L L L +N+ +P + + L IDL NP
Sbjct: 350 LARLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGNP 384
Score = 39.1 bits (87), Expect = 0.019
Identities = 17/41 (41%), Positives = 26/41 (63%)
Frame = +2
Query: 551 LAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 673
L KL+ L L +N I LPD + R +L H ++R NR+++ P
Sbjct: 6 LHKLKVLILNDNLISFLPDNIFRFASLTHLDIRGNRIQKLP 46
>AL080239-3|CAI41650.1| 837|Homo sapiens novel protein protein.
Length = 837
Score = 49.6 bits (113), Expect = 1e-05
Identities = 43/155 (27%), Positives = 69/155 (44%), Gaps = 4/155 (2%)
Frame = +2
Query: 350 NLVNLNLSYNPL-NVLIPEIGDLEKLEAFWCNRIGLKEIPKEI-GKLTQLDTFGARGNEL 523
N L+++ N + +V + + D E L+ + I ++ LT L GN++
Sbjct: 378 NAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQI 437
Query: 524 KTI-PEEMTSLAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQFPSSILKCKE 697
+ + PE + L L++L LE N I+ + T D M L L NN L+ P I
Sbjct: 438 ERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAP 497
Query: 698 LMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNP 802
L L L +N+ +P + + L IDL NP
Sbjct: 498 LARLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGNP 532
Score = 43.6 bits (98), Expect = 9e-04
Identities = 43/165 (26%), Positives = 73/165 (44%), Gaps = 8/165 (4%)
Frame = +2
Query: 203 TCLEVEH-LYLHKNKISIF---PVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNLNL 370
+C+ VE+ LY++ K+S++ ++ P N + V+L+L
Sbjct: 31 SCVSVENVLYVNCEKVSVYRPNQLKPPWSNFYHLNFQNNFLNILYPNTFLNFSHAVSLHL 90
Query: 371 SYNPL-NVLIPEIGDLEKLEAFWCNRIGLKEIPKE--IGKLTQLDTFGARGNELKTIPE- 538
N L N+ L L+ N LK + + +G + L+ A N +K I
Sbjct: 91 GNNKLQNIEGGAFLGLSALKQLHLNNNELKILRADTFLG-IENLEYLQADYNLIKYIERG 149
Query: 539 EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP 673
L KL+ L L +N I LPD + R +L H ++R NR+++ P
Sbjct: 150 AFNKLHKLKVLILNDNLISFLPDNIFRFASLTHLDIRGNRIQKLP 194
>AK057619-1|BAB71535.1| 469|Homo sapiens protein ( Homo sapiens
cDNA FLJ33057 fis, clone TRACH1000144, weakly similar to
CHONDROADHERIN PRECURSOR. ).
Length = 469
Score = 49.6 bits (113), Expect = 1e-05
Identities = 43/155 (27%), Positives = 69/155 (44%), Gaps = 4/155 (2%)
Frame = +2
Query: 350 NLVNLNLSYNPL-NVLIPEIGDLEKLEAFWCNRIGLKEIPKEI-GKLTQLDTFGARGNEL 523
N L+++ N + +V + + D E L+ + I ++ LT L GN++
Sbjct: 10 NAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQI 69
Query: 524 KTI-PEEMTSLAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQFPSSILKCKE 697
+ + PE + L L++L LE N I+ + T D M L L NN L+ P I
Sbjct: 70 ERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAP 129
Query: 698 LMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNP 802
L L L +N+ +P + + L IDL NP
Sbjct: 130 LARLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGNP 164
>BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 49.2 bits (112), Expect = 2e-05
Identities = 36/142 (25%), Positives = 72/142 (50%), Gaps = 5/142 (3%)
Frame = +2
Query: 329 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEK---LEAFWCNRIGLKEIPKEIGKLTQLDT 499
+ + +L++L + L+ N L IP +G + L + NRI ++ +P+ + + L+T
Sbjct: 92 SSMSHLQSLREVKLNNNELET-IPNLGPVSANITLLSLAGNRI-VEILPEHLKEFQSLET 149
Query: 500 FGARGNELKTIPEEMTSLAKLRWLTLENNQIETL-PDTMDRMT-ALVHCNLRNNRLEQFP 673
N + + +L +L++L L +N++ ++ P D + L+ L NR+ P
Sbjct: 150 LDLSSNNISELQTAFPAL-QLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIP 208
Query: 674 SSILKCKELMFLQLNSNQISSV 739
+ K +L L+LN N+I +V
Sbjct: 209 PKMFKLPQLQHLELNRNKIKNV 230
>BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 49.2 bits (112), Expect = 2e-05
Identities = 36/142 (25%), Positives = 72/142 (50%), Gaps = 5/142 (3%)
Frame = +2
Query: 329 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEK---LEAFWCNRIGLKEIPKEIGKLTQLDT 499
+ + +L++L + L+ N L IP +G + L + NRI ++ +P+ + + L+T
Sbjct: 92 SSMSHLQSLREVKLNNNELET-IPNLGPVSANITLLSLAGNRI-VEILPEHLKEFQSLET 149
Query: 500 FGARGNELKTIPEEMTSLAKLRWLTLENNQIETL-PDTMDRMT-ALVHCNLRNNRLEQFP 673
N + + +L +L++L L +N++ ++ P D + L+ L NR+ P
Sbjct: 150 LDLSSNNISELQTAFPAL-QLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIP 208
Query: 674 SSILKCKELMFLQLNSNQISSV 739
+ K +L L+LN N+I +V
Sbjct: 209 PKMFKLPQLQHLELNRNKIKNV 230
>AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 49.2 bits (112), Expect = 2e-05
Identities = 36/142 (25%), Positives = 72/142 (50%), Gaps = 5/142 (3%)
Frame = +2
Query: 329 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEK---LEAFWCNRIGLKEIPKEIGKLTQLDT 499
+ + +L++L + L+ N L IP +G + L + NRI ++ +P+ + + L+T
Sbjct: 92 SSMSHLQSLREVKLNNNELET-IPNLGPVSANITLLSLAGNRI-VEILPEHLKEFQSLET 149
Query: 500 FGARGNELKTIPEEMTSLAKLRWLTLENNQIETL-PDTMDRMT-ALVHCNLRNNRLEQFP 673
N + + +L +L++L L +N++ ++ P D + L+ L NR+ P
Sbjct: 150 LDLSSNNISELQTAFPAL-QLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIP 208
Query: 674 SSILKCKELMFLQLNSNQISSV 739
+ K +L L+LN N+I +V
Sbjct: 209 PKMFKLPQLQHLELNRNKIKNV 230
>AY358733-1|AAQ89095.1| 622|Homo sapiens CGLQ1891 protein.
Length = 622
Score = 49.2 bits (112), Expect = 2e-05
Identities = 59/222 (26%), Positives = 94/222 (42%), Gaps = 10/222 (4%)
Frame = +2
Query: 188 PGLLYTCLEVEHLYLHKNKISIFP---VEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLV 358
PG+ L + +LYL N++S P T +G + L
Sbjct: 125 PGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVG-MVALR 183
Query: 359 NLNLSYNPLNVL-IPEIG--DLEKLEAFWCNRIGLKEIPKEIGK-LTQLDTFGARGNELK 526
L+LS N N+L I E G LE L + L ++P + L L N ++
Sbjct: 184 ILDLSNN--NILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIE 241
Query: 527 TI-PEEMTSLAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQFPSSILK-CKE 697
I P LA L +L L+N++I + D + L H L +N LE S K
Sbjct: 242 AIQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKN 301
Query: 698 LMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELSHP 823
L++L+L+ N+I S+ + ++ L +++L N + L HP
Sbjct: 302 LIYLKLDRNRIISIDNDTFENMGASLKILNLSFNNLTAL-HP 342
>AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein.
Length = 1059
Score = 49.2 bits (112), Expect = 2e-05
Identities = 36/142 (25%), Positives = 72/142 (50%), Gaps = 5/142 (3%)
Frame = +2
Query: 329 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEK---LEAFWCNRIGLKEIPKEIGKLTQLDT 499
+ + +L++L + L+ N L IP +G + L + NRI ++ +P+ + + L+T
Sbjct: 32 SSMSHLQSLREVKLNNNELET-IPNLGPVSANITLLSLAGNRI-VEILPEHLKEFQSLET 89
Query: 500 FGARGNELKTIPEEMTSLAKLRWLTLENNQIETL-PDTMDRMT-ALVHCNLRNNRLEQFP 673
N + + +L +L++L L +N++ ++ P D + L+ L NR+ P
Sbjct: 90 LDLSSNNISELQTAFPAL-QLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIP 148
Query: 674 SSILKCKELMFLQLNSNQISSV 739
+ K +L L+LN N+I +V
Sbjct: 149 PKMFKLPQLQHLELNRNKIKNV 170
>AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein.
Length = 1119
Score = 49.2 bits (112), Expect = 2e-05
Identities = 36/142 (25%), Positives = 72/142 (50%), Gaps = 5/142 (3%)
Frame = +2
Query: 329 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEK---LEAFWCNRIGLKEIPKEIGKLTQLDT 499
+ + +L++L + L+ N L IP +G + L + NRI ++ +P+ + + L+T
Sbjct: 92 SSMSHLQSLREVKLNNNELET-IPNLGPVSANITLLSLAGNRI-VEILPEHLKEFQSLET 149
Query: 500 FGARGNELKTIPEEMTSLAKLRWLTLENNQIETL-PDTMDRMT-ALVHCNLRNNRLEQFP 673
N + + +L +L++L L +N++ ++ P D + L+ L NR+ P
Sbjct: 150 LDLSSNNISELQTAFPAL-QLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIP 208
Query: 674 SSILKCKELMFLQLNSNQISSV 739
+ K +L L+LN N+I +V
Sbjct: 209 PKMFKLPQLQHLELNRNKIKNV 230
>AY280614-1|AAP36706.1| 622|Homo sapiens synleurin protein.
Length = 622
Score = 49.2 bits (112), Expect = 2e-05
Identities = 59/222 (26%), Positives = 94/222 (42%), Gaps = 10/222 (4%)
Frame = +2
Query: 188 PGLLYTCLEVEHLYLHKNKISIFP---VEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLV 358
PG+ L + +LYL N++S P T +G + L
Sbjct: 125 PGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVG-MVALR 183
Query: 359 NLNLSYNPLNVL-IPEIG--DLEKLEAFWCNRIGLKEIPKEIGK-LTQLDTFGARGNELK 526
L+LS N N+L I E G LE L + L ++P + L L N ++
Sbjct: 184 ILDLSNN--NILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIE 241
Query: 527 TI-PEEMTSLAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQFPSSILK-CKE 697
I P LA L +L L+N++I + D + L H L +N LE S K
Sbjct: 242 AIQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKN 301
Query: 698 LMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELSHP 823
L++L+L+ N+I S+ + ++ L +++L N + L HP
Sbjct: 302 LIYLKLDRNRIISIDNDTFENMGASLKILNLSFNNLTAL-HP 342
>AK123022-1|BAC85517.1| 622|Homo sapiens protein ( Homo sapiens
cDNA FLJ41026 fis, clone BRAMY2004771, weakly similar
to CHONDROADHERIN PRECURSOR. ).
Length = 622
Score = 49.2 bits (112), Expect = 2e-05
Identities = 59/222 (26%), Positives = 94/222 (42%), Gaps = 10/222 (4%)
Frame = +2
Query: 188 PGLLYTCLEVEHLYLHKNKISIFP---VEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLV 358
PG+ L + +LYL N++S P T +G + L
Sbjct: 125 PGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVG-MVALR 183
Query: 359 NLNLSYNPLNVL-IPEIG--DLEKLEAFWCNRIGLKEIPKEIGK-LTQLDTFGARGNELK 526
L+LS N N+L I E G LE L + L ++P + L L N ++
Sbjct: 184 ILDLSNN--NILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIE 241
Query: 527 TI-PEEMTSLAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQFPSSILK-CKE 697
I P LA L +L L+N++I + D + L H L +N LE S K
Sbjct: 242 AIQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKN 301
Query: 698 LMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELSHP 823
L++L+L+ N+I S+ + ++ L +++L N + L HP
Sbjct: 302 LIYLKLDRNRIISIDNDTFENMGASLKILNLSFNNLTAL-HP 342
>AB209743-1|BAD92980.1| 1032|Homo sapiens Leucine-rich
repeat-containing G protein-coupled receptor 4 precursor
variant protein.
Length = 1032
Score = 49.2 bits (112), Expect = 2e-05
Identities = 59/227 (25%), Positives = 93/227 (40%), Gaps = 7/227 (3%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCL-EVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
L L+ IT +P + L ++ HL+L N ++ PV
Sbjct: 215 LRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALTLALNKISSIP 274
Query: 332 EIG--NLKNLVNLNLSYNPLNVLIPEIGD-LEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
+ NL +LV L+L N + L D L+ LE N L E P+ I L L
Sbjct: 275 DFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEFPQAIKALPSLKEL 334
Query: 503 GARGNELKTIPE-EMTSLAKLRWLTLENNQIETLPDT-MDRMTALVHCNLRN-NRLEQFP 673
G N + IP+ LR + L +N + + ++ ++ L +R + ++QFP
Sbjct: 335 GFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASMVQQFP 394
Query: 674 SSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
++ L L L +ISS+P NL L +DL N I +L
Sbjct: 395 -NLTGTVHLESLTLTGTKISSIPNNL-CQEQKMLRTLDLSYNNIRDL 439
Score = 48.4 bits (110), Expect = 3e-05
Identities = 37/125 (29%), Positives = 64/125 (51%), Gaps = 4/125 (3%)
Frame = +2
Query: 452 LKEIPKEIGK-LTQLDTFGARGNELKTI-PEEMTSLAKLRWLTLENNQIETLPDTMDR-M 622
+ ++P++ K L+ GN+L I P+ ++ L +L+ LTL+NNQ++T+P R +
Sbjct: 150 ITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGL 209
Query: 623 TALVHCNLRNNRLEQFP-SSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSN 799
+AL L N + P S +L L L+ N ++ VP + S +P L + L N
Sbjct: 210 SALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVH-PLSNLPTLQALTLALN 268
Query: 800 PICEL 814
I +
Sbjct: 269 KISSI 273
>BC101073-1|AAI01074.1| 841|Homo sapiens SLIT and NTRK-like family,
member 6 protein.
Length = 841
Score = 48.8 bits (111), Expect = 2e-05
Identities = 37/109 (33%), Positives = 49/109 (44%), Gaps = 2/109 (1%)
Frame = +2
Query: 482 LTQLDTFGARGNELKTIPEEM-TSLAKLRWLTLENNQI-ETLPDTMDRMTALVHCNLRNN 655
LT+L GN L + + M L L +L LE N I E LP T + M L L NN
Sbjct: 410 LTRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYNAIKEILPGTFNPMPKLKVLYLNNN 469
Query: 656 RLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNP 802
L+ P I L + L +NQ + +P + + L IDL NP
Sbjct: 470 LLQVLPPHIFSGVPLTKVNLKTNQFTHLPVSNILDDLDLLTQIDLEDNP 518
Score = 48.4 bits (110), Expect = 3e-05
Identities = 40/138 (28%), Positives = 65/138 (47%), Gaps = 6/138 (4%)
Frame = +2
Query: 332 EIGNLKNLVNLNLSYNPL-NVLIPEIGDLEKLEAFWCNRIGLKEIPKE--IGKLTQLDTF 502
+ L N ++++L +N + ++ I L L+ N L EI KE L L+
Sbjct: 83 DFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSL-EILKEDTFHGLENLEFL 141
Query: 503 GARGNELKTI-PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP-- 673
A N + I P + L +L+ L L +N IE+LP + R L H +LR N+L+ P
Sbjct: 142 QADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIFRFVPLTHLDLRGNQLQTLPYV 201
Query: 674 SSILKCKELMFLQLNSNQ 727
+ ++ LQL N+
Sbjct: 202 GFLEHIGRILDLQLEDNK 219
Score = 37.9 bits (84), Expect = 0.045
Identities = 31/92 (33%), Positives = 43/92 (46%), Gaps = 2/92 (2%)
Frame = +2
Query: 551 LAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQF-PSSILKCKELMFLQLNSN 724
L L+ L + +N +E L DT + L NN + PS+ K L L LN N
Sbjct: 111 LGLLKQLHINHNSLEILKEDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDN 170
Query: 725 QISSVPANLDTSLVPGLXMIDLRSNPICELSH 820
I S+P N+ VP L +DLR N + L +
Sbjct: 171 AIESLPPNI-FRFVP-LTHLDLRGNQLQTLPY 200
>BC101072-1|AAI01073.1| 841|Homo sapiens SLIT and NTRK-like family,
member 6 protein.
Length = 841
Score = 48.8 bits (111), Expect = 2e-05
Identities = 37/109 (33%), Positives = 49/109 (44%), Gaps = 2/109 (1%)
Frame = +2
Query: 482 LTQLDTFGARGNELKTIPEEM-TSLAKLRWLTLENNQI-ETLPDTMDRMTALVHCNLRNN 655
LT+L GN L + + M L L +L LE N I E LP T + M L L NN
Sbjct: 410 LTRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYNAIKEILPGTFNPMPKLKVLYLNNN 469
Query: 656 RLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNP 802
L+ P I L + L +NQ + +P + + L IDL NP
Sbjct: 470 LLQVLPPHIFSGVPLTKVNLKTNQFTHLPVSNILDDLDLLTQIDLEDNP 518
Score = 48.4 bits (110), Expect = 3e-05
Identities = 40/138 (28%), Positives = 65/138 (47%), Gaps = 6/138 (4%)
Frame = +2
Query: 332 EIGNLKNLVNLNLSYNPL-NVLIPEIGDLEKLEAFWCNRIGLKEIPKE--IGKLTQLDTF 502
+ L N ++++L +N + ++ I L L+ N L EI KE L L+
Sbjct: 83 DFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSL-EILKEDTFHGLENLEFL 141
Query: 503 GARGNELKTI-PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP-- 673
A N + I P + L +L+ L L +N IE+LP + R L H +LR N+L+ P
Sbjct: 142 QADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIFRFVPLTHLDLRGNQLQTLPYV 201
Query: 674 SSILKCKELMFLQLNSNQ 727
+ ++ LQL N+
Sbjct: 202 GFLEHIGRILDLQLEDNK 219
Score = 37.9 bits (84), Expect = 0.045
Identities = 31/92 (33%), Positives = 43/92 (46%), Gaps = 2/92 (2%)
Frame = +2
Query: 551 LAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQF-PSSILKCKELMFLQLNSN 724
L L+ L + +N +E L DT + L NN + PS+ K L L LN N
Sbjct: 111 LGLLKQLHINHNSLEILKEDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDN 170
Query: 725 QISSVPANLDTSLVPGLXMIDLRSNPICELSH 820
I S+P N+ VP L +DLR N + L +
Sbjct: 171 AIESLPPNI-FRFVP-LTHLDLRGNQLQTLPY 200
>BC101071-1|AAI01072.1| 841|Homo sapiens SLIT and NTRK-like family,
member 6 protein.
Length = 841
Score = 48.8 bits (111), Expect = 2e-05
Identities = 37/109 (33%), Positives = 49/109 (44%), Gaps = 2/109 (1%)
Frame = +2
Query: 482 LTQLDTFGARGNELKTIPEEM-TSLAKLRWLTLENNQI-ETLPDTMDRMTALVHCNLRNN 655
LT+L GN L + + M L L +L LE N I E LP T + M L L NN
Sbjct: 410 LTRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYNAIKEILPGTFNPMPKLKVLYLNNN 469
Query: 656 RLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNP 802
L+ P I L + L +NQ + +P + + L IDL NP
Sbjct: 470 LLQVLPPHIFSGVPLTKVNLKTNQFTHLPVSNILDDLDLLTQIDLEDNP 518
Score = 48.4 bits (110), Expect = 3e-05
Identities = 40/138 (28%), Positives = 65/138 (47%), Gaps = 6/138 (4%)
Frame = +2
Query: 332 EIGNLKNLVNLNLSYNPL-NVLIPEIGDLEKLEAFWCNRIGLKEIPKE--IGKLTQLDTF 502
+ L N ++++L +N + ++ I L L+ N L EI KE L L+
Sbjct: 83 DFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSL-EILKEDTFHGLENLEFL 141
Query: 503 GARGNELKTI-PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP-- 673
A N + I P + L +L+ L L +N IE+LP + R L H +LR N+L+ P
Sbjct: 142 QADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIFRFVPLTHLDLRGNQLQTLPYV 201
Query: 674 SSILKCKELMFLQLNSNQ 727
+ ++ LQL N+
Sbjct: 202 GFLEHIGRILDLQLEDNK 219
Score = 37.9 bits (84), Expect = 0.045
Identities = 31/92 (33%), Positives = 43/92 (46%), Gaps = 2/92 (2%)
Frame = +2
Query: 551 LAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQF-PSSILKCKELMFLQLNSN 724
L L+ L + +N +E L DT + L NN + PS+ K L L LN N
Sbjct: 111 LGLLKQLHINHNSLEILKEDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDN 170
Query: 725 QISSVPANLDTSLVPGLXMIDLRSNPICELSH 820
I S+P N+ VP L +DLR N + L +
Sbjct: 171 AIESLPPNI-FRFVP-LTHLDLRGNQLQTLPY 200
>BC101070-1|AAI01071.1| 841|Homo sapiens SLIT and NTRK-like family,
member 6 protein.
Length = 841
Score = 48.8 bits (111), Expect = 2e-05
Identities = 37/109 (33%), Positives = 49/109 (44%), Gaps = 2/109 (1%)
Frame = +2
Query: 482 LTQLDTFGARGNELKTIPEEM-TSLAKLRWLTLENNQI-ETLPDTMDRMTALVHCNLRNN 655
LT+L GN L + + M L L +L LE N I E LP T + M L L NN
Sbjct: 410 LTRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYNAIKEILPGTFNPMPKLKVLYLNNN 469
Query: 656 RLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNP 802
L+ P I L + L +NQ + +P + + L IDL NP
Sbjct: 470 LLQVLPPHIFSGVPLTKVNLKTNQFTHLPVSNILDDLDLLTQIDLEDNP 518
Score = 48.4 bits (110), Expect = 3e-05
Identities = 40/138 (28%), Positives = 65/138 (47%), Gaps = 6/138 (4%)
Frame = +2
Query: 332 EIGNLKNLVNLNLSYNPL-NVLIPEIGDLEKLEAFWCNRIGLKEIPKE--IGKLTQLDTF 502
+ L N ++++L +N + ++ I L L+ N L EI KE L L+
Sbjct: 83 DFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSL-EILKEDTFHGLENLEFL 141
Query: 503 GARGNELKTI-PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP-- 673
A N + I P + L +L+ L L +N IE+LP + R L H +LR N+L+ P
Sbjct: 142 QADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIFRFVPLTHLDLRGNQLQTLPYV 201
Query: 674 SSILKCKELMFLQLNSNQ 727
+ ++ LQL N+
Sbjct: 202 GFLEHIGRILDLQLEDNK 219
Score = 37.9 bits (84), Expect = 0.045
Identities = 31/92 (33%), Positives = 43/92 (46%), Gaps = 2/92 (2%)
Frame = +2
Query: 551 LAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQF-PSSILKCKELMFLQLNSN 724
L L+ L + +N +E L DT + L NN + PS+ K L L LN N
Sbjct: 111 LGLLKQLHINHNSLEILKEDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDN 170
Query: 725 QISSVPANLDTSLVPGLXMIDLRSNPICELSH 820
I S+P N+ VP L +DLR N + L +
Sbjct: 171 AIESLPPNI-FRFVP-LTHLDLRGNQLQTLPY 200
>AK026427-1|BAB15480.1| 440|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22774 fis, clone KAIA1575. ).
Length = 440
Score = 48.4 bits (110), Expect = 3e-05
Identities = 40/138 (28%), Positives = 65/138 (47%), Gaps = 6/138 (4%)
Frame = +2
Query: 332 EIGNLKNLVNLNLSYNPL-NVLIPEIGDLEKLEAFWCNRIGLKEIPKE--IGKLTQLDTF 502
+ L N ++++L +N + ++ I L L+ N L EI KE L L+
Sbjct: 40 DFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSL-EILKEDTFHGLENLEFL 98
Query: 503 GARGNELKTI-PEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFP-- 673
A N + I P + L +L+ L L +N IE+LP + R L H +LR N+L+ P
Sbjct: 99 QADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIFRFVPLTHLDLRGNQLQTLPYV 158
Query: 674 SSILKCKELMFLQLNSNQ 727
+ ++ LQL N+
Sbjct: 159 GFLEHIGRILDLQLEDNK 176
Score = 37.9 bits (84), Expect = 0.045
Identities = 31/92 (33%), Positives = 43/92 (46%), Gaps = 2/92 (2%)
Frame = +2
Query: 551 LAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQF-PSSILKCKELMFLQLNSN 724
L L+ L + +N +E L DT + L NN + PS+ K L L LN N
Sbjct: 68 LGLLKQLHINHNSLEILKEDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDN 127
Query: 725 QISSVPANLDTSLVPGLXMIDLRSNPICELSH 820
I S+P N+ VP L +DLR N + L +
Sbjct: 128 AIESLPPNI-FRFVP-LTHLDLRGNQLQTLPY 157
>AF346711-1|AAK31153.1| 951|Homo sapiens G-protein couple receptor
protein.
Length = 951
Score = 48.4 bits (110), Expect = 3e-05
Identities = 37/125 (29%), Positives = 64/125 (51%), Gaps = 4/125 (3%)
Frame = +2
Query: 452 LKEIPKEIGK-LTQLDTFGARGNELKTI-PEEMTSLAKLRWLTLENNQIETLPDTMDR-M 622
+ ++P++ K L+ GN+L I P+ ++ L +L+ LTL+NNQ++T+P R +
Sbjct: 69 ITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGL 128
Query: 623 TALVHCNLRNNRLEQFP-SSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSN 799
+AL L N + P S +L L L+ N ++ VP + S +P L + L N
Sbjct: 129 SALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVH-PLSNLPTLQALTLALN 187
Query: 800 PICEL 814
I +
Sbjct: 188 KISSI 192
Score = 44.4 bits (100), Expect = 5e-04
Identities = 57/227 (25%), Positives = 92/227 (40%), Gaps = 7/227 (3%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCL-EVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
L L+ IT +P + L ++ HL+L N ++ PV
Sbjct: 134 LRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALTLALNKISSIP 193
Query: 332 EIG--NLKNLVNLNLSYNPLNVLIPEIGD-LEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
+ NL +LV L+L N + L D L+ LE + L E P+ I L
Sbjct: 194 DFAFTNLSSLVVLHLHNNKIRGLSQHCFDGLDNLETLDLSYNNLGEFPQAIKARPSLKEL 253
Query: 503 GARGNELKTIPE-EMTSLAKLRWLTLENNQIETLPDT-MDRMTALVHCNLRN-NRLEQFP 673
G N + IP+ LR + L +N + + ++ ++ L +R + ++QFP
Sbjct: 254 GFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASMVQQFP 313
Query: 674 SSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
++ L L L +ISS+P NL L +DL N I +L
Sbjct: 314 -NLTGTVHLESLTLTGTKISSIPNNL-CQEQKMLRTLDLSYNNIRDL 358
>AF257182-1|AAF68989.1| 951|Homo sapiens G-protein-coupled receptor
48 protein.
Length = 951
Score = 48.4 bits (110), Expect = 3e-05
Identities = 37/125 (29%), Positives = 64/125 (51%), Gaps = 4/125 (3%)
Frame = +2
Query: 452 LKEIPKEIGK-LTQLDTFGARGNELKTI-PEEMTSLAKLRWLTLENNQIETLPDTMDR-M 622
+ ++P++ K L+ GN+L I P+ ++ L +L+ LTL+NNQ++T+P R +
Sbjct: 69 ITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGL 128
Query: 623 TALVHCNLRNNRLEQFP-SSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSN 799
+AL L N + P S +L L L+ N ++ VP + S +P L + L N
Sbjct: 129 SALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVH-PLSNLPTLQALTLALN 187
Query: 800 PICEL 814
I +
Sbjct: 188 KISSI 192
Score = 45.2 bits (102), Expect = 3e-04
Identities = 56/227 (24%), Positives = 91/227 (40%), Gaps = 7/227 (3%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCL-EVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
L L+ IT +P + L ++ HL+L N ++ PV
Sbjct: 134 LRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALTLALNKISSIP 193
Query: 332 EIG--NLKNLVNLNLSYNPLNVLIPEIGD-LEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
+ NL +LV L+L N + L D L+ LE + L E P+ I L
Sbjct: 194 DFAFTNLSSLVVLHLHNNKIRGLSQHCFDGLDNLETLDLSYNNLGEFPQAIKARPSLKEL 253
Query: 503 GARGNELKTIPE-EMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRN--NRLEQFP 673
G N + IP+ LR + L +N + + ++ + +H + + ++QFP
Sbjct: 254 GFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSASHNLSDLHSLVIRGASMVQQFP 313
Query: 674 SSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
++ L L L +ISS+P NL L +DL N I +L
Sbjct: 314 -NLTGTVHLESLTLTGTKISSIPNNL-CQEQKMLRTLDLSYNNIRDL 358
>BC082244-1|AAH82244.1| 465|Homo sapiens PHLPP protein protein.
Length = 465
Score = 48.0 bits (109), Expect = 4e-05
Identities = 26/101 (25%), Positives = 53/101 (52%)
Frame = +2
Query: 440 NRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDR 619
+R L+ +P+ + + +L+ N++ +P + + LR L +NQ+ LP+ ++R
Sbjct: 126 SRNRLENVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNQLARLPERLER 185
Query: 620 MTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVP 742
+ V N LE P+ ++K L FL ++N++ S+P
Sbjct: 186 TSVEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESLP 226
Score = 47.6 bits (108), Expect = 6e-05
Identities = 52/228 (22%), Positives = 89/228 (39%), Gaps = 6/228 (2%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTE 334
L + +I E+P L+ + L N+++ P P
Sbjct: 146 LDIGHNQICELPARLFCNSSLRKLLAGHNQLARLPERLERTSVEVLDVQHNQLLELPPNL 205
Query: 335 IGNLKNLVNLNLSYNPLNVLIPEIGDLEK---LEAFWCNRIGLKE--IPKEIGKLTQLDT 499
+ +L LN S N L L P E L+ + L + +P G L
Sbjct: 206 LMKADSLRFLNASANKLESLPPATLSEETNSILQELYLTNNSLTDKCVPLLTGH-PHLKI 264
Query: 500 FGARGNELKTIP-EEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPS 676
N L++ P +M L +L + L N+++ +P T+ + +N +E FP
Sbjct: 265 LHMAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPE 324
Query: 677 SILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELSH 820
+++ E+ + L+ N++S V L +L P L +DL NP L H
Sbjct: 325 -VMQLPEIKCVDLSCNELSEV--TLPENLPPKLQELDLTGNPRLVLDH 369
Score = 32.3 bits (70), Expect = 2.2
Identities = 19/64 (29%), Positives = 32/64 (50%)
Frame = +2
Query: 560 LRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSV 739
L+ L +N++ L D L + ++ NRLE P + + ++L L + NQI +
Sbjct: 98 LKALYASSNELVQL-DVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICEL 156
Query: 740 PANL 751
PA L
Sbjct: 157 PARL 160
>BC031301-1|AAH31301.1| 583|Homo sapiens leucine rich repeat
containing 47 protein.
Length = 583
Score = 48.0 bits (109), Expect = 4e-05
Identities = 48/166 (28%), Positives = 74/166 (44%), Gaps = 12/166 (7%)
Frame = +2
Query: 344 LKNLVNLNLSYNPLNV-LIPEIGDLEKLEAFWCNRIGLKEIPKEIGK-------LTQLDT 499
L L +L L N L L PE+G L L + L+ +P G L QL +
Sbjct: 74 LPQLHSLVLRRNALGPGLSPELGPLPALRVLDLSGNALEALPPGQGLGPAEPPGLPQLQS 133
Query: 500 FGARGNELKTIPEEMTSLA-KLRWLTLENNQIETLPDTMDRMTALVHCN---LRNNRLEQ 667
GN L+ +P ++ A +L+ L L N +++ P + R AL + +N L +
Sbjct: 134 LNLSGNRLRELPADLARCAPRLQSLNLTGNCLDSFPAELFRPGALPLLSELAAADNCLRE 193
Query: 668 FPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
I L L L++NQ+S +PA L + P L I+ R N +
Sbjct: 194 LSPDIAHLASLKTLDLSNNQLSEIPAEL--ADCPKLKEINFRGNKL 237
Score = 45.2 bits (102), Expect = 3e-04
Identities = 35/116 (30%), Positives = 51/116 (43%), Gaps = 4/116 (3%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLE-KLEAFWCNRIGLKEIPKEI---GKLTQL 493
P E L L +LNLS N L L ++ +L++ L P E+ G L L
Sbjct: 122 PAEPPGLPQLQSLNLSGNRLRELPADLARCAPRLQSLNLTGNCLDSFPAELFRPGALPLL 181
Query: 494 DTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRL 661
A N L+ + ++ LA L+ L L NNQ+ +P + L N R N+L
Sbjct: 182 SELAAADNCLRELSPDIAHLASLKTLDLSNNQLSEIPAELADCPKLKEINFRGNKL 237
Score = 32.7 bits (71), Expect = 1.7
Identities = 21/63 (33%), Positives = 29/63 (46%)
Frame = +2
Query: 338 GNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGN 517
G L L L + N L L P+I L L+ + L EIP E+ +L RGN
Sbjct: 176 GALPLLSELAAADNCLRELSPDIAHLASLKTLDLSNNQLSEIPAELADCPKLKEINFRGN 235
Query: 518 ELK 526
+L+
Sbjct: 236 KLR 238
>AL365330-3|CAI42528.1| 583|Homo sapiens leucine rich repeat
containing 47 protein.
Length = 583
Score = 48.0 bits (109), Expect = 4e-05
Identities = 48/166 (28%), Positives = 74/166 (44%), Gaps = 12/166 (7%)
Frame = +2
Query: 344 LKNLVNLNLSYNPLNV-LIPEIGDLEKLEAFWCNRIGLKEIPKEIGK-------LTQLDT 499
L L +L L N L L PE+G L L + L+ +P G L QL +
Sbjct: 74 LPQLHSLVLRRNALGPGLSPELGPLPALRVLDLSGNALEALPPGQGLGPAEPPGLPQLQS 133
Query: 500 FGARGNELKTIPEEMTSLA-KLRWLTLENNQIETLPDTMDRMTALVHCN---LRNNRLEQ 667
GN L+ +P ++ A +L+ L L N +++ P + R AL + +N L +
Sbjct: 134 LNLSGNRLRELPADLARCAPRLQSLNLTGNCLDSFPAELFRPGALPLLSELAAADNCLRE 193
Query: 668 FPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
I L L L++NQ+S +PA L + P L I+ R N +
Sbjct: 194 LSPDIAHLASLKTLDLSNNQLSEIPAEL--ADCPKLKEINFRGNKL 237
Score = 45.2 bits (102), Expect = 3e-04
Identities = 35/116 (30%), Positives = 51/116 (43%), Gaps = 4/116 (3%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLE-KLEAFWCNRIGLKEIPKEI---GKLTQL 493
P E L L +LNLS N L L ++ +L++ L P E+ G L L
Sbjct: 122 PAEPPGLPQLQSLNLSGNRLRELPADLARCAPRLQSLNLTGNCLDSFPAELFRPGALPLL 181
Query: 494 DTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRL 661
A N L+ + ++ LA L+ L L NNQ+ +P + L N R N+L
Sbjct: 182 SELAAADNCLRELSPDIAHLASLKTLDLSNNQLSEIPAELADCPKLKEINFRGNKL 237
Score = 32.7 bits (71), Expect = 1.7
Identities = 21/63 (33%), Positives = 29/63 (46%)
Frame = +2
Query: 338 GNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGN 517
G L L L + N L L P+I L L+ + L EIP E+ +L RGN
Sbjct: 176 GALPLLSELAAADNCLRELSPDIAHLASLKTLDLSNNQLSEIPAELADCPKLKEINFRGN 235
Query: 518 ELK 526
+L+
Sbjct: 236 KLR 238
>Z23091-1|CAA80637.1| 560|Homo sapiens platelet glycoprotein V
precursor protein.
Length = 560
Score = 47.2 bits (107), Expect = 7e-05
Identities = 33/96 (34%), Positives = 48/96 (50%), Gaps = 2/96 (2%)
Frame = +2
Query: 533 PEEMTSLAKLRWLTLENNQIETLPDTM-DRMTALVHCNLRNNRLEQFPSSIL-KCKELMF 706
P + L KL+ L L N+I LP + D+M L L +N L ++ K L
Sbjct: 91 PGTFSDLIKLKTLRLSRNKITHLPGALLDKMVLLEQLFLDHNALRGIDQNMFQKLVNLQE 150
Query: 707 LQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
L LN NQ+ +PA+L T+L L ++DL N + L
Sbjct: 151 LALNQNQLDFLPASLFTNL-ENLKLLDLSGNNLTHL 185
Score = 36.3 bits (80), Expect = 0.14
Identities = 32/113 (28%), Positives = 55/113 (48%), Gaps = 8/113 (7%)
Frame = +2
Query: 341 NLKNLVNLNLSYNPLNVLIPE--IGDLEKLEAFWCNRIGLKEIP----KEIGKLTQLDTF 502
NL L L ++ +P +P+ L +L+ + GL +P + +GKL Q+
Sbjct: 312 NLSRLRYLGVTLSPRLSALPQGAFQGLGELQVLALHSNGLTALPDGLLRGLGKLRQVSL- 370
Query: 503 GARGNELKTIPEEM-TSLAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNN 655
R N L+ +P + +L+ L + L++NQ+ETLP D + L L +N
Sbjct: 371 --RRNRLRALPRALFRNLSSLESVQLDHNQLETLPGDVFGALPRLTEVLLGHN 421
>L11238-1|AAA03069.1| 560|Homo sapiens platelet membrane
glycoprotein V protein.
Length = 560
Score = 47.2 bits (107), Expect = 7e-05
Identities = 33/96 (34%), Positives = 48/96 (50%), Gaps = 2/96 (2%)
Frame = +2
Query: 533 PEEMTSLAKLRWLTLENNQIETLPDTM-DRMTALVHCNLRNNRLEQFPSSIL-KCKELMF 706
P + L KL+ L L N+I LP + D+M L L +N L ++ K L
Sbjct: 91 PGTFSDLIKLKTLRLSRNKITHLPGALLDKMVLLEQLFLDHNALRGIDQNMFQKLVNLQE 150
Query: 707 LQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
L LN NQ+ +PA+L T+L L ++DL N + L
Sbjct: 151 LALNQNQLDFLPASLFTNL-ENLKLLDLSGNNLTHL 185
Score = 36.3 bits (80), Expect = 0.14
Identities = 32/113 (28%), Positives = 55/113 (48%), Gaps = 8/113 (7%)
Frame = +2
Query: 341 NLKNLVNLNLSYNPLNVLIPE--IGDLEKLEAFWCNRIGLKEIP----KEIGKLTQLDTF 502
NL L L ++ +P +P+ L +L+ + GL +P + +GKL Q+
Sbjct: 312 NLSRLRYLGVTLSPRLSALPQGAFQGLGELQVLALHSNGLTALPDGLLRGLGKLRQVSL- 370
Query: 503 GARGNELKTIPEEM-TSLAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNN 655
R N L+ +P + +L+ L + L++NQ+ETLP D + L L +N
Sbjct: 371 --RRNRLRALPRALFRNLSSLESVQLDHNQLETLPGDVFGALPRLTEVLLGHN 421
>BC070198-1|AAH70198.1| 347|Homo sapiens leucine-rich
alpha-2-glycoprotein 1 protein.
Length = 347
Score = 46.8 bits (106), Expect = 1e-04
Identities = 46/146 (31%), Positives = 69/146 (47%), Gaps = 2/146 (1%)
Frame = +2
Query: 383 LNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKL 562
L+ L+ + LE LE W + GLK L LD G R +L P + + L
Sbjct: 142 LDTLVLKENQLEVLEVSWLH--GLKA-------LGHLDLSGNRLRKLP--PGLLANFTLL 190
Query: 563 RWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQFPSSILKCK-ELMFLQLNSNQISS 736
R L L NQ+ETL PD + L +L N+L+ +L + +L +L LN N+++
Sbjct: 191 RTLDLGENQLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLAR 250
Query: 737 VPANLDTSLVPGLXMIDLRSNPICEL 814
V A L L M+DL +N + +
Sbjct: 251 VAAGAFQGL-RQLDMLDLSNNSLASV 275
>BC034389-1|AAH34389.1| 347|Homo sapiens leucine-rich
alpha-2-glycoprotein 1 protein.
Length = 347
Score = 46.8 bits (106), Expect = 1e-04
Identities = 46/146 (31%), Positives = 69/146 (47%), Gaps = 2/146 (1%)
Frame = +2
Query: 383 LNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKL 562
L+ L+ + LE LE W + GLK L LD G R +L P + + L
Sbjct: 142 LDTLVLKENQLEVLEVSWLH--GLKA-------LGHLDLSGNRLRKLP--PGLLANFTLL 190
Query: 563 RWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQFPSSILKCK-ELMFLQLNSNQISS 736
R L L NQ+ETL PD + L +L N+L+ +L + +L +L LN N+++
Sbjct: 191 RTLDLGENQLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLAR 250
Query: 737 VPANLDTSLVPGLXMIDLRSNPICEL 814
V A L L M+DL +N + +
Sbjct: 251 VAAGAFQGL-RQLDMLDLSNNSLASV 275
>BC018370-1|AAH18370.1| 674|Homo sapiens fibronectin leucine rich
transmembrane protein 1 protein.
Length = 674
Score = 46.8 bits (106), Expect = 1e-04
Identities = 55/217 (25%), Positives = 87/217 (40%), Gaps = 7/217 (3%)
Frame = +2
Query: 185 IPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNL 364
IP L T + V+ +YL++N + FP+ + + + L L
Sbjct: 98 IPQDLKTKVNVQVIYLYENDLDEFPINLPRSLRELHLQDNNVRTIARDS-LARIPLLEKL 156
Query: 365 NLSYNPLNVLIPE---IGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 535
+L N ++ + E D ++L+ + +R L IP G L+ N + TIP
Sbjct: 157 HLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPS--GLPHTLEELRLDDNRISTIP 214
Query: 536 -EEMTSLAKLRWLTLENNQI---ETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELM 703
L LR L L+ N + DT R+ L +L N L P + L L
Sbjct: 215 LHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAAPPLN-LPSAHLQ 273
Query: 704 FLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
L L N IS +P N + + L +DL +N + L
Sbjct: 274 KLYLQDNAISHIPYN-TLAKMRELERLDLSNNNLTTL 309
>AY358308-1|AAQ88675.1| 674|Homo sapiens FLRT1 protein.
Length = 674
Score = 46.8 bits (106), Expect = 1e-04
Identities = 55/217 (25%), Positives = 87/217 (40%), Gaps = 7/217 (3%)
Frame = +2
Query: 185 IPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNL 364
IP L T + V+ +YL++N + FP+ + + + L L
Sbjct: 98 IPQDLKTKVNVQVIYLYENDLDEFPINLPRSLRELHLQDNNVRTIARDS-LARIPLLEKL 156
Query: 365 NLSYNPLNVLIPE---IGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 535
+L N ++ + E D ++L+ + +R L IP G L+ N + TIP
Sbjct: 157 HLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPS--GLPHTLEELRLDDNRISTIP 214
Query: 536 -EEMTSLAKLRWLTLENNQI---ETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELM 703
L LR L L+ N + DT R+ L +L N L P + L L
Sbjct: 215 LHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAAPPLN-LPSAHLQ 273
Query: 704 FLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
L L N IS +P N + + L +DL +N + L
Sbjct: 274 KLYLQDNAISHIPYN-TLAKMRELERLDLSNNNLTTL 309
>AF403428-1|AAK95527.1| 347|Homo sapiens leucine-rich
alpha-2-glycoprotein protein.
Length = 347
Score = 46.8 bits (106), Expect = 1e-04
Identities = 46/146 (31%), Positives = 69/146 (47%), Gaps = 2/146 (1%)
Frame = +2
Query: 383 LNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKL 562
L+ L+ + LE LE W + GLK L LD G R +L P + + L
Sbjct: 142 LDTLVLKENQLEVLEVSWLH--GLKA-------LGHLDLSGNRLRKLP--PGLLANFTLL 190
Query: 563 RWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQFPSSILKCK-ELMFLQLNSNQISS 736
R L L NQ+ETL PD + L +L N+L+ +L + +L +L LN N+++
Sbjct: 191 RTLDLGENQLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLAR 250
Query: 737 VPANLDTSLVPGLXMIDLRSNPICEL 814
V A L L M+DL +N + +
Sbjct: 251 VAAGAFQGL-RQLDMLDLSNNSLASV 275
>AF169675-1|AAF28459.1| 674|Homo sapiens leucine-rich repeat
transmembrane protein FLRT1 protein.
Length = 674
Score = 46.8 bits (106), Expect = 1e-04
Identities = 55/217 (25%), Positives = 87/217 (40%), Gaps = 7/217 (3%)
Frame = +2
Query: 185 IPGLLYTCLEVEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPTEIGNLKNLVNL 364
IP L T + V+ +YL++N + FP+ + + + L L
Sbjct: 98 IPQDLKTKVNVQVIYLYENDLDEFPINLPRSLRELHLQDNNVRTIARDS-LARIPLLEKL 156
Query: 365 NLSYNPLNVLIPE---IGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIP 535
+L N ++ + E D ++L+ + +R L IP G L+ N + TIP
Sbjct: 157 HLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPS--GLPHTLEELRLDDNRISTIP 214
Query: 536 -EEMTSLAKLRWLTLENNQI---ETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKELM 703
L LR L L+ N + DT R+ L +L N L P + L L
Sbjct: 215 LHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAAPPLN-LPSAHLQ 273
Query: 704 FLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
L L N IS +P N + + L +DL +N + L
Sbjct: 274 KLYLQDNAISHIPYN-TLAKMRELERLDLSNNNLTTL 309
>AB073607-1|BAD38644.1| 347|Homo sapiens leucine-rich
alpha-2-glycoprotein protein.
Length = 347
Score = 46.8 bits (106), Expect = 1e-04
Identities = 46/146 (31%), Positives = 69/146 (47%), Gaps = 2/146 (1%)
Frame = +2
Query: 383 LNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKL 562
L+ L+ + LE LE W + GLK L LD G R +L P + + L
Sbjct: 142 LDTLVLKENQLEVLEVSWLH--GLKA-------LGHLDLSGNRLRKLP--PGLLANFTLL 190
Query: 563 RWLTLENNQIETL-PDTMDRMTALVHCNLRNNRLEQFPSSILKCK-ELMFLQLNSNQISS 736
R L L NQ+ETL PD + L +L N+L+ +L + +L +L LN N+++
Sbjct: 191 RTLDLGENQLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLAR 250
Query: 737 VPANLDTSLVPGLXMIDLRSNPICEL 814
V A L L M+DL +N + +
Sbjct: 251 VAAGAFQGL-RQLDMLDLSNNSLASV 275
>BC096326-1|AAH96326.1| 883|Homo sapiens LGR5 protein protein.
Length = 883
Score = 46.0 bits (104), Expect = 2e-04
Identities = 65/252 (25%), Positives = 103/252 (40%), Gaps = 29/252 (11%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLE-VEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
L L+ I+ +P ++ L + HL+L N ++ PV+
Sbjct: 143 LRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIP 202
Query: 332 E--IGNLKNLVNLNLSYNPLNVLIPEIGD-LEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
+ GNL +LV L+L N ++ L + D L LE N L E P I L+ L
Sbjct: 203 DYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKEL 262
Query: 503 GARGN--------------ELKTIP----------EEMTSLAKLRWLTLENNQIETLPDT 610
N EL+T+ ++T A L LTL QI +LP T
Sbjct: 263 HFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFPDLTGTANLESLTLTGAQISSLPQT 322
Query: 611 M-DRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMID 787
+ +++ L +L N LE PS + C++L + L N+I + + L+ L ++
Sbjct: 323 VCNQLPNLQVLDLSYNLLEDLPSFSV-CQKLQKIDLRHNEIYEIKVDTFQQLL-SLRSLN 380
Query: 788 LRSNPICELSHP 823
L N I + HP
Sbjct: 381 LAWNKIA-IIHP 391
Score = 41.1 bits (92), Expect = 0.005
Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 3/104 (2%)
Frame = +2
Query: 461 IPKEIGKLTQLDTFGARGNELKTIPE-EMTSLAKLRWLTLENNQIETLP-DTMDRMTALV 634
+P + L L+ GN L IP+ T L L+ L L+NNQ+ +P + + + +L
Sbjct: 82 LPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQ 141
Query: 635 HCNLRNNRLEQFPSSILK-CKELMFLQLNSNQISSVPANLDTSL 763
L N + P S L L L+ N ++ +P SL
Sbjct: 142 SLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSL 185
>BC096325-1|AAH96325.1| 883|Homo sapiens LGR5 protein protein.
Length = 883
Score = 46.0 bits (104), Expect = 2e-04
Identities = 65/252 (25%), Positives = 103/252 (40%), Gaps = 29/252 (11%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLYTCLE-VEHLYLHKNKISIFPVEXXXXXXXXXXXXXXXXXXXXPT 331
L L+ I+ +P ++ L + HL+L N ++ PV+
Sbjct: 143 LRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIP 202
Query: 332 E--IGNLKNLVNLNLSYNPLNVLIPEIGD-LEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
+ GNL +LV L+L N ++ L + D L LE N L E P I L+ L
Sbjct: 203 DYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKEL 262
Query: 503 GARGN--------------ELKTIP----------EEMTSLAKLRWLTLENNQIETLPDT 610
N EL+T+ ++T A L LTL QI +LP T
Sbjct: 263 HFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFPDLTGTANLESLTLTGAQISSLPQT 322
Query: 611 M-DRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMID 787
+ +++ L +L N LE PS + C++L + L N+I + + L+ L ++
Sbjct: 323 VCNQLPNLQVLDLSYNLLEDLPSFSV-CQKLQKIDLRHNEIYEIKVDTFQQLL-SLRSLN 380
Query: 788 LRSNPICELSHP 823
L N I + HP
Sbjct: 381 LAWNKIA-IIHP 391
Score = 41.1 bits (92), Expect = 0.005
Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 3/104 (2%)
Frame = +2
Query: 461 IPKEIGKLTQLDTFGARGNELKTIPE-EMTSLAKLRWLTLENNQIETLP-DTMDRMTALV 634
+P + L L+ GN L IP+ T L L+ L L+NNQ+ +P + + + +L
Sbjct: 82 LPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQ 141
Query: 635 HCNLRNNRLEQFPSSILK-CKELMFLQLNSNQISSVPANLDTSL 763
L N + P S L L L+ N ++ +P SL
Sbjct: 142 SLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSL 185
>BC057786-1|AAH57786.1| 512|Homo sapiens podocan-like 1 protein.
Length = 512
Score = 46.0 bits (104), Expect = 2e-04
Identities = 38/133 (28%), Positives = 66/133 (49%), Gaps = 5/133 (3%)
Frame = +2
Query: 353 LVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPK-EIGKLTQLDTFGARGNELKT 529
+ L+LS N L+ L P + LE + ++P+ + + TQL + N+L
Sbjct: 197 IATLSLSNNQLSYLPPSLPP--SLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQLTD 254
Query: 530 IPEEMTSLAKLR---WLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILK-CKE 697
+ T+ +KL +L L +NQ+ T+P + R A++H L NR+ Q ++ L +
Sbjct: 255 SGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILH--LGRNRIRQVEAARLHGARG 312
Query: 698 LMFLQLNSNQISS 736
L +L L NQ+ S
Sbjct: 313 LRYLLLQHNQLGS 325
Score = 45.2 bits (102), Expect = 3e-04
Identities = 34/113 (30%), Positives = 59/113 (52%), Gaps = 4/113 (3%)
Frame = +2
Query: 488 QLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRL- 661
++DT G +L+ P+ +T A+ L+L+NNQ++ LP + + R++ L NL NN +
Sbjct: 54 RVDTVDCDGLDLRVFPDNITRAAQ--HLSLQNNQLQELPYNELSRLSGLRTLNLHNNLIS 111
Query: 662 -EQFPSSILK-CKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICEL 814
E P + +L L + N++S P L S L + DL +N + E+
Sbjct: 112 SEGLPDEAFESLTQLQHLCVAHNKLSVAPQFLPRS----LRVADLAANQVMEI 160
Score = 38.7 bits (86), Expect = 0.026
Identities = 28/93 (30%), Positives = 45/93 (48%), Gaps = 4/93 (4%)
Frame = +2
Query: 497 TFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLP-DTMDRMTALVHCNLRNNRLEQF- 670
T N+L +P + L L L+NN I +P + R T L L++N+L
Sbjct: 199 TLSLSNNQLSYLPPSLPP--SLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQLTDSG 256
Query: 671 --PSSILKCKELMFLQLNSNQISSVPANLDTSL 763
++ K L +L L+ NQ+++VPA L +L
Sbjct: 257 LDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTL 289
Score = 33.1 bits (72), Expect = 1.3
Identities = 37/143 (25%), Positives = 59/143 (41%), Gaps = 6/143 (4%)
Frame = +2
Query: 332 EIGNLKNLVNLNLSYNPLNVL-IPE--IGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
E+ L L LNL N ++ +P+ L +L+ L P+ + + ++
Sbjct: 93 ELSRLSGLRTLNLHNNLISSEGLPDEAFESLTQLQHLCVAHNKLSVAPQFLPRSLRVADL 152
Query: 503 GARGNELKTIPEEMTSLAKLRWLTLENNQIETL---PDTMDRMTALVHCNLRNNRLEQFP 673
A ++ P LR + L NNQ+ PD A+ +L NN+L P
Sbjct: 153 AAN-QVMEIFPLTFGEKPALRSVYLHNNQLSNAGLPPDAFRGSEAIATLSLSNNQLSYLP 211
Query: 674 SSILKCKELMFLQLNSNQISSVP 742
S+ E + LQ +N IS VP
Sbjct: 212 PSLPPSLERLHLQ--NNLISKVP 232
>AK058188-1|BAB71707.1| 475|Homo sapiens protein ( Homo sapiens
cDNA FLJ25459 fis, clone TST09038. ).
Length = 475
Score = 46.0 bits (104), Expect = 2e-04
Identities = 34/90 (37%), Positives = 47/90 (52%), Gaps = 1/90 (1%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFG 505
P +I L NLV L+LS N L L E+G++ L N L+ +P E+G+L QL F
Sbjct: 72 PPDIAKLHNLVYLDLSSNKLRSLPAELGNMVSLRELLLNNNLLRVLPYELGRLFQLLNFM 131
Query: 506 ARGNELKTIPEEMTSLAKLRWLTL-ENNQI 592
+ L PE+ L W+TL E +QI
Sbjct: 132 L--DNLAVHPEQ---LPPRPWITLKERDQI 156
Score = 41.9 bits (94), Expect = 0.003
Identities = 23/90 (25%), Positives = 42/90 (46%)
Frame = +2
Query: 452 LKEIPKEIGKLTQLDTFGARGNELKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTAL 631
++ + + LT L N L IP ++ L L +L L +N++ +LP + M +L
Sbjct: 45 VRSLSTSLWSLTHLTALHLNDNYLSRIPPDIAKLHNLVYLDLSSNKLRSLPAELGNMVSL 104
Query: 632 VHCNLRNNRLEQFPSSILKCKELMFLQLNS 721
L NN L P + + +L+ L++
Sbjct: 105 RELLLNNNLLRVLPYELGRLFQLLNFMLDN 134
Score = 39.1 bits (87), Expect = 0.019
Identities = 27/94 (28%), Positives = 46/94 (48%), Gaps = 2/94 (2%)
Frame = +2
Query: 329 TEIGNLKNLVNLNLSYNPLNVLIPEIGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGA 508
T + +L +L L+L+ N L+ + P+I L L + L+ +P E+G + L
Sbjct: 50 TSLWSLTHLTALHLNDNYLSRIPPDIAKLHNLVYLDLSSNKLRSLPAELGNMVSLRELLL 109
Query: 509 RGNELKTIPEEMTSLAKLRWLTLENNQI--ETLP 604
N L+ +P E+ L +L L+N + E LP
Sbjct: 110 NNNLLRVLPYELGRLFQLLNFMLDNLAVHPEQLP 143
Score = 38.3 bits (85), Expect = 0.034
Identities = 20/77 (25%), Positives = 40/77 (51%)
Frame = +2
Query: 521 LKTIPEEMTSLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNRLEQFPSSILKCKEL 700
++++ + SL L L L +N + +P + ++ LV+ +L +N+L P+ + L
Sbjct: 45 VRSLSTSLWSLTHLTALHLNDNYLSRIPPDIAKLHNLVYLDLSSNKLRSLPAELGNMVSL 104
Query: 701 MFLQLNSNQISSVPANL 751
L LN+N + +P L
Sbjct: 105 RELLLNNNLLRVLPYEL 121
>BC117180-1|AAI17181.1| 2527|Homo sapiens leucine-rich repeat kinase 2
protein.
Length = 2527
Score = 45.2 bits (102), Expect = 3e-04
Identities = 34/119 (28%), Positives = 57/119 (47%), Gaps = 5/119 (4%)
Frame = +2
Query: 482 LTQLDTFGARGNELKTIPEEMT-SLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNR 658
L L+ N L + P+++ +L L L L +N+ + P + +M+ + + ++ N
Sbjct: 1010 LEHLEKLELHQNALTSFPQQLCETLKSLTHLDLHSNKFTSFPSYLLKMSCIANLDVSRND 1069
Query: 659 LEQFPSSIL----KCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELSHP 823
+ PS +L KC L L+ NQ+S VP NL T +V L + L N I + P
Sbjct: 1070 IG--PSVVLDPTVKCPTLKQFNLSYNQLSFVPENL-TDVVEKLEQLILEGNKISGICSP 1125
Score = 38.3 bits (85), Expect = 0.034
Identities = 29/80 (36%), Positives = 43/80 (53%), Gaps = 3/80 (3%)
Frame = +2
Query: 350 NLVNLNLSYNPLNVL-IPEIGDL-EKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGN-E 520
NL L S+N +++L + E L ++E + LKEIP EIG L L + N E
Sbjct: 1221 NLRELLFSHNQISILDLSEKAYLWSRVEKLHLSHNKLKEIPPEIGCLENLTSLDVSYNLE 1280
Query: 521 LKTIPEEMTSLAKLRWLTLE 580
L++ P EM L+K+ L L+
Sbjct: 1281 LRSFPNEMGKLSKIWDLPLD 1300
Score = 37.1 bits (82), Expect = 0.078
Identities = 29/133 (21%), Positives = 55/133 (41%), Gaps = 4/133 (3%)
Frame = +2
Query: 419 KLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEM---TSLAKLRWLTLENNQ 589
KL++ + + + E +T LD ++ + ++ L L L L N
Sbjct: 963 KLQSHMRHSDSISSLASEREYITSLDLSANELRDIDALSQKCCISVHLEHLEKLELHQNA 1022
Query: 590 IETLPDTM-DRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLV 766
+ + P + + + +L H +L +N+ FPS +LK + L ++ N I T
Sbjct: 1023 LTSFPQQLCETLKSLTHLDLHSNKFTSFPSYLLKMSCIANLDVSRNDIGPSVVLDPTVKC 1082
Query: 767 PGLXMIDLRSNPI 805
P L +L N +
Sbjct: 1083 PTLKQFNLSYNQL 1095
Score = 33.1 bits (72), Expect = 1.3
Identities = 32/140 (22%), Positives = 59/140 (42%), Gaps = 4/140 (2%)
Frame = +2
Query: 341 NLKNLVNLNLSYNPLNVLIPEIGD-LEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGN 517
+L++L L L N L ++ + L+ L + P + K++ + N
Sbjct: 1009 HLEHLEKLELHQNALTSFPQQLCETLKSLTHLDLHSNKFTSFPSYLLKMSCIANLDVSRN 1068
Query: 518 EL--KTIPEEMTSLAKLRWLTLENNQIETLPDTM-DRMTALVHCNLRNNRLEQFPSSILK 688
++ + + L+ L NQ+ +P+ + D + L L N++ S L+
Sbjct: 1069 DIGPSVVLDPTVKCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGNKISGICSP-LR 1127
Query: 689 CKELMFLQLNSNQISSVPAN 748
KEL L L+ N ISS+ N
Sbjct: 1128 LKELKILNLSKNHISSLSEN 1147
Score = 30.7 bits (66), Expect = 6.8
Identities = 26/94 (27%), Positives = 40/94 (42%), Gaps = 4/94 (4%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLY-TCLEVEHLYLHKNKISIFPVEXXXX--XXXXXXXXXXXXXXXX 325
L ++ +I +PG + L + L N+ISI +
Sbjct: 1201 LDMSSNDIQYLPGPAHWKSLNLRELLFSHNQISILDLSEKAYLWSRVEKLHLSHNKLKEI 1260
Query: 326 PTEIGNLKNLVNLNLSYN-PLNVLIPEIGDLEKL 424
P EIG L+NL +L++SYN L E+G L K+
Sbjct: 1261 PPEIGCLENLTSLDVSYNLELRSFPNEMGKLSKI 1294
>AY792511-1|AAV63975.1| 2527|Homo sapiens leucine-rich repeat kinase 2
protein.
Length = 2527
Score = 45.2 bits (102), Expect = 3e-04
Identities = 34/119 (28%), Positives = 57/119 (47%), Gaps = 5/119 (4%)
Frame = +2
Query: 482 LTQLDTFGARGNELKTIPEEMT-SLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNR 658
L L+ N L + P+++ +L L L L +N+ + P + +M+ + + ++ N
Sbjct: 1010 LEHLEKLELHQNALTSFPQQLCETLKSLTHLDLHSNKFTSFPSYLLKMSCIANLDVSRND 1069
Query: 659 LEQFPSSIL----KCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELSHP 823
+ PS +L KC L L+ NQ+S VP NL T +V L + L N I + P
Sbjct: 1070 IG--PSVVLDPTVKCPTLKQFNLSYNQLSFVPENL-TDVVEKLEQLILEGNKISGICSP 1125
Score = 38.3 bits (85), Expect = 0.034
Identities = 29/80 (36%), Positives = 43/80 (53%), Gaps = 3/80 (3%)
Frame = +2
Query: 350 NLVNLNLSYNPLNVL-IPEIGDL-EKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGN-E 520
NL L S+N +++L + E L ++E + LKEIP EIG L L + N E
Sbjct: 1221 NLRELLFSHNQISILDLSEKAYLWSRVEKLHLSHNKLKEIPPEIGCLENLTSLDVSYNLE 1280
Query: 521 LKTIPEEMTSLAKLRWLTLE 580
L++ P EM L+K+ L L+
Sbjct: 1281 LRSFPNEMGKLSKIWDLPLD 1300
Score = 37.1 bits (82), Expect = 0.078
Identities = 29/133 (21%), Positives = 55/133 (41%), Gaps = 4/133 (3%)
Frame = +2
Query: 419 KLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEM---TSLAKLRWLTLENNQ 589
KL++ + + + E +T LD ++ + ++ L L L L N
Sbjct: 963 KLQSHMRHSDSISSLASEREYITSLDLSANELRDIDALSQKCCISVHLEHLEKLELHQNA 1022
Query: 590 IETLPDTM-DRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLV 766
+ + P + + + +L H +L +N+ FPS +LK + L ++ N I T
Sbjct: 1023 LTSFPQQLCETLKSLTHLDLHSNKFTSFPSYLLKMSCIANLDVSRNDIGPSVVLDPTVKC 1082
Query: 767 PGLXMIDLRSNPI 805
P L +L N +
Sbjct: 1083 PTLKQFNLSYNQL 1095
Score = 33.1 bits (72), Expect = 1.3
Identities = 32/140 (22%), Positives = 59/140 (42%), Gaps = 4/140 (2%)
Frame = +2
Query: 341 NLKNLVNLNLSYNPLNVLIPEIGD-LEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGN 517
+L++L L L N L ++ + L+ L + P + K++ + N
Sbjct: 1009 HLEHLEKLELHQNALTSFPQQLCETLKSLTHLDLHSNKFTSFPSYLLKMSCIANLDVSRN 1068
Query: 518 EL--KTIPEEMTSLAKLRWLTLENNQIETLPDTM-DRMTALVHCNLRNNRLEQFPSSILK 688
++ + + L+ L NQ+ +P+ + D + L L N++ S L+
Sbjct: 1069 DIGPSVVLDPTVKCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGNKISGICSP-LR 1127
Query: 689 CKELMFLQLNSNQISSVPAN 748
KEL L L+ N ISS+ N
Sbjct: 1128 LKELKILNLSKNHISSLSEN 1147
Score = 30.7 bits (66), Expect = 6.8
Identities = 26/94 (27%), Positives = 40/94 (42%), Gaps = 4/94 (4%)
Frame = +2
Query: 155 LSLNGFEITEIPGLLY-TCLEVEHLYLHKNKISIFPVEXXXX--XXXXXXXXXXXXXXXX 325
L ++ +I +PG + L + L N+ISI +
Sbjct: 1201 LDMSSNDIQYLPGPAHWKSLNLRELLFSHNQISILDLSEKAYLWSRVEKLHLSHNKLKEI 1260
Query: 326 PTEIGNLKNLVNLNLSYN-PLNVLIPEIGDLEKL 424
P EIG L+NL +L++SYN L E+G L K+
Sbjct: 1261 PPEIGCLENLTSLDVSYNLELRSFPNEMGKLSKI 1294
>AY730707-1|AAU44786.1| 1093|Homo sapiens leucine-rich repeat
protein LRIG1 protein.
Length = 1093
Score = 45.2 bits (102), Expect = 3e-04
Identities = 40/165 (24%), Positives = 72/165 (43%), Gaps = 5/165 (3%)
Frame = +2
Query: 326 PTEIGNLKNLVNLNLSYNPLNVLIPE-IGDLEKLEAFWCNRIGLKEIPKEIGKLTQLDTF 502
P +L NL +NLSYN L+ + P DL L+ + N L +P + + +
Sbjct: 85 PAGFEDLPNLQEVNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVPSLGAASSHVVSL 144
Query: 503 GARGNELKTIP-EEMTSLAKLRWLTLENNQIETLPDT-MDRMTALVHCNLRNNRLEQFPS 676
+ N+++++ ++ + L L L N I + +T + NL NR+
Sbjct: 145 FLQHNKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLEL 204
Query: 677 SILK--CKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPI 805
+ L+ L+L+ N+I+ +P +P L +DL N I
Sbjct: 205 GAFDGLSRSLLTLRLSKNRITQLPVR--AFKLPRLTQLDLNRNRI 247
>AK127729-1|BAC87105.1| 870|Homo sapiens protein ( Homo sapiens
cDNA FLJ45829 fis, clone NT2RP8006452. ).
Length = 870
Score = 45.2 bits (102), Expect = 3e-04
Identities = 34/119 (28%), Positives = 57/119 (47%), Gaps = 5/119 (4%)
Frame = +2
Query: 482 LTQLDTFGARGNELKTIPEEMT-SLAKLRWLTLENNQIETLPDTMDRMTALVHCNLRNNR 658
L L+ N L + P+++ +L L L L +N+ + P + +M+ + + ++ N
Sbjct: 609 LEHLEKLELHQNALTSFPQQLCETLKSLTHLDLHSNKFTSFPSYLLKMSCIANLDVSRND 668
Query: 659 LEQFPSSIL----KCKELMFLQLNSNQISSVPANLDTSLVPGLXMIDLRSNPICELSHP 823
+ PS +L KC L L+ NQ+S VP NL T +V L + L N I + P
Sbjct: 669 IG--PSVVLDPTVKCPTLKQFNLSYNQLSFVPENL-TDVVEKLEQLILEGNKISGICSP 724
Score = 37.1 bits (82), Expect = 0.078
Identities = 29/133 (21%), Positives = 55/133 (41%), Gaps = 4/133 (3%)
Frame = +2
Query: 419 KLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGNELKTIPEEM---TSLAKLRWLTLENNQ 589
KL++ + + + E +T LD ++ + ++ L L L L N
Sbjct: 562 KLQSHMRHSDSISSLASEREYITSLDLSANELRDIDALSQKCCISVHLEHLEKLELHQNA 621
Query: 590 IETLPDTM-DRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLV 766
+ + P + + + +L H +L +N+ FPS +LK + L ++ N I T
Sbjct: 622 LTSFPQQLCETLKSLTHLDLHSNKFTSFPSYLLKMSCIANLDVSRNDIGPSVVLDPTVKC 681
Query: 767 PGLXMIDLRSNPI 805
P L +L N +
Sbjct: 682 PTLKQFNLSYNQL 694
Score = 33.1 bits (72), Expect = 1.3
Identities = 32/140 (22%), Positives = 59/140 (42%), Gaps = 4/140 (2%)
Frame = +2
Query: 341 NLKNLVNLNLSYNPLNVLIPEIGD-LEKLEAFWCNRIGLKEIPKEIGKLTQLDTFGARGN 517
+L++L L L N L ++ + L+ L + P + K++ + N
Sbjct: 608 HLEHLEKLELHQNALTSFPQQLCETLKSLTHLDLHSNKFTSFPSYLLKMSCIANLDVSRN 667
Query: 518 EL--KTIPEEMTSLAKLRWLTLENNQIETLPDTM-DRMTALVHCNLRNNRLEQFPSSILK 688
++ + + L+ L NQ+ +P+ + D + L L N++ S L+
Sbjct: 668 DIGPSVVLDPTVKCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGNKISGICSP-LR 726
Query: 689 CKELMFLQLNSNQISSVPAN 748
KEL L L+ N ISS+ N
Sbjct: 727 LKELKILNLSKNHISSLSEN 746
>BC030608-1|AAH30608.1| 661|Homo sapiens podocan protein.
Length = 661
Score = 44.8 bits (101), Expect = 4e-04
Identities = 35/135 (25%), Positives = 68/135 (50%), Gaps = 4/135 (2%)
Frame = +2
Query: 437 CNRIGLKEIPKEIGKLTQLDTFGARGNELKTI-PEEMTSLAKLRWLTLENNQIET--LPD 607
C I L+E P ++ + T + + N+L+ I PEE++ L +L L L+NN++ + LP+
Sbjct: 130 CGGIDLREFPGDLPEHT--NHLSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPE 187
Query: 608 -TMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMI 784
+ +T L + L NN+L P + L+ + +N ++ + L P L +
Sbjct: 188 KAFEHLTNLNYLYLANNKLTLAPRFLPNA--LISVDFAANYLTKI-YGLTFGQKPNLRSV 244
Query: 785 DLRSNPICELSHPEH 829
L +N + + P++
Sbjct: 245 YLHNNKLADAGLPDN 259
Score = 39.1 bits (87), Expect = 0.019
Identities = 29/88 (32%), Positives = 45/88 (51%), Gaps = 4/88 (4%)
Frame = +2
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPD-TMDRMTALVHCNLRNNRLEQFP---SSI 682
N L+ +P+ + L L L+NN++E +P +++L L+NN L +
Sbjct: 275 NFLRHVPKHLPPA--LYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETF 332
Query: 683 LKCKELMFLQLNSNQISSVPANLDTSLV 766
K L +L L+SN +S VPA L SLV
Sbjct: 333 WKLSSLEYLDLSSNNLSRVPAGLPRSLV 360
>AY358294-1|AAQ88661.1| 642|Homo sapiens EGEE293 protein.
Length = 642
Score = 44.8 bits (101), Expect = 4e-04
Identities = 35/135 (25%), Positives = 68/135 (50%), Gaps = 4/135 (2%)
Frame = +2
Query: 437 CNRIGLKEIPKEIGKLTQLDTFGARGNELKTI-PEEMTSLAKLRWLTLENNQIET--LPD 607
C I L+E P ++ + T + + N+L+ I PEE++ L +L L L+NN++ + LP+
Sbjct: 111 CGGIDLREFPGDLPEHT--NHLSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPE 168
Query: 608 -TMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMI 784
+ +T L + L NN+L P + L+ + +N ++ + L P L +
Sbjct: 169 KAFEHLTNLNYLYLANNKLTLAPRFLPNA--LISVDFAANYLTKI-YGLTFGQKPNLRSV 225
Query: 785 DLRSNPICELSHPEH 829
L +N + + P++
Sbjct: 226 YLHNNKLADAGLPDN 240
Score = 39.1 bits (87), Expect = 0.019
Identities = 29/88 (32%), Positives = 45/88 (51%), Gaps = 4/88 (4%)
Frame = +2
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPD-TMDRMTALVHCNLRNNRLEQFP---SSI 682
N L+ +P+ + L L L+NN++E +P +++L L+NN L +
Sbjct: 256 NFLRHVPKHLPPA--LYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETF 313
Query: 683 LKCKELMFLQLNSNQISSVPANLDTSLV 766
K L +L L+SN +S VPA L SLV
Sbjct: 314 WKLSSLEYLDLSSNNLSRVPAGLPRSLV 341
>AY313607-1|AAP79898.1| 613|Homo sapiens podocan protein protein.
Length = 613
Score = 44.8 bits (101), Expect = 4e-04
Identities = 35/135 (25%), Positives = 68/135 (50%), Gaps = 4/135 (2%)
Frame = +2
Query: 437 CNRIGLKEIPKEIGKLTQLDTFGARGNELKTI-PEEMTSLAKLRWLTLENNQIET--LPD 607
C I L+E P ++ + T + + N+L+ I PEE++ L +L L L+NN++ + LP+
Sbjct: 82 CGGIDLREFPGDLPEHT--NHLSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPE 139
Query: 608 -TMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMI 784
+ +T L + L NN+L P + L+ + +N ++ + L P L +
Sbjct: 140 KAFEHLTNLNYLYLANNKLTLAPRFLPNA--LISVDFAANYLTKI-YGLTFGQKPNLRSV 196
Query: 785 DLRSNPICELSHPEH 829
L +N + + P++
Sbjct: 197 YLHNNKLADAGLPDN 211
Score = 39.1 bits (87), Expect = 0.019
Identities = 29/88 (32%), Positives = 45/88 (51%), Gaps = 4/88 (4%)
Frame = +2
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPD-TMDRMTALVHCNLRNNRLEQFP---SSI 682
N L+ +P+ + L L L+NN++E +P +++L L+NN L +
Sbjct: 227 NFLRHVPKHLPPA--LYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETF 284
Query: 683 LKCKELMFLQLNSNQISSVPANLDTSLV 766
K L +L L+SN +S VPA L SLV
Sbjct: 285 WKLSSLEYLDLSSNNLSRVPAGLPRSLV 312
>AL445183-5|CAH72592.1| 642|Homo sapiens podocan protein.
Length = 642
Score = 44.8 bits (101), Expect = 4e-04
Identities = 35/135 (25%), Positives = 68/135 (50%), Gaps = 4/135 (2%)
Frame = +2
Query: 437 CNRIGLKEIPKEIGKLTQLDTFGARGNELKTI-PEEMTSLAKLRWLTLENNQIET--LPD 607
C I L+E P ++ + T + + N+L+ I PEE++ L +L L L+NN++ + LP+
Sbjct: 111 CGGIDLREFPGDLPEHT--NHLSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPE 168
Query: 608 -TMDRMTALVHCNLRNNRLEQFPSSILKCKELMFLQLNSNQISSVPANLDTSLVPGLXMI 784
+ +T L + L NN+L P + L+ + +N ++ + L P L +
Sbjct: 169 KAFEHLTNLNYLYLANNKLTLAPRFLPNA--LISVDFAANYLTKI-YGLTFGQKPNLRSV 225
Query: 785 DLRSNPICELSHPEH 829
L +N + + P++
Sbjct: 226 YLHNNKLADAGLPDN 240
Score = 39.1 bits (87), Expect = 0.019
Identities = 29/88 (32%), Positives = 45/88 (51%), Gaps = 4/88 (4%)
Frame = +2
Query: 515 NELKTIPEEMTSLAKLRWLTLENNQIETLPD-TMDRMTALVHCNLRNNRLEQFP---SSI 682
N L+ +P+ + L L L+NN++E +P +++L L+NN L +
Sbjct: 256 NFLRHVPKHLPPA--LYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETF 313
Query: 683 LKCKELMFLQLNSNQISSVPANLDTSLV 766
K L +L L+SN +S VPA L SLV
Sbjct: 314 WKLSSLEYLDLSSNNLSRVPAGLPRSLV 341
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 96,385,077
Number of Sequences: 237096
Number of extensions: 1731682
Number of successful extensions: 6272
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 4224
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5366
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10426655866
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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