Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P02_pT_J06
(724 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein. 342 7e-94
CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein. 342 7e-94
BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein pr... 342 7e-94
BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein. 342 7e-94
AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitr... 342 7e-94
AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein. 342 7e-94
BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenas... 341 2e-93
CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein. 339 5e-93
AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitra... 337 3e-92
DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenas... 328 1e-89
X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase... 300 4e-81
U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase ... 299 6e-81
BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenas... 299 6e-81
BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenas... 299 6e-81
AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenas... 297 2e-80
AF197566-1|AAG43470.1| 127|Homo sapiens NADP+-specific isocitra... 128 3e-29
U62389-1|AAB17375.1| 154|Homo sapiens putative cytosolic NADP-d... 69 1e-11
>CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 342 bits (841), Expect = 7e-94
Identities = 156/193 (80%), Positives = 170/193 (88%)
Frame = -2
Query: 723 YDGRFKDIFQDIYDREYKXQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACXNYDGDVQS 544
YDGRFKDIFQ+IYD++YK QFE IWYEHRLIDDMVA AMKSEGGF+WAC NYDGDVQS
Sbjct: 219 YDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQS 278
Query: 543 DSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFAWTR 364
DSVAQGYGSLG+MTSVL+CPDGKTVEAEAAHGTVTRH+R YQ+G+ETSTNPIASIFAWTR
Sbjct: 279 DSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTR 338
Query: 363 GLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYYETFEFM 184
GL HRAKLDNN L FA LE+V IETIE+G MTKDLA CIKG+ NV+RSDY TFEFM
Sbjct: 339 GLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFM 398
Query: 183 DKLAENLKVALGQ 145
DKL ENLK+ L Q
Sbjct: 399 DKLGENLKIKLAQ 411
>CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 342 bits (841), Expect = 7e-94
Identities = 156/193 (80%), Positives = 170/193 (88%)
Frame = -2
Query: 723 YDGRFKDIFQDIYDREYKXQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACXNYDGDVQS 544
YDGRFKDIFQ+IYD++YK QFE IWYEHRLIDDMVA AMKSEGGF+WAC NYDGDVQS
Sbjct: 219 YDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQS 278
Query: 543 DSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFAWTR 364
DSVAQGYGSLG+MTSVL+CPDGKTVEAEAAHGTVTRH+R YQ+G+ETSTNPIASIFAWTR
Sbjct: 279 DSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTR 338
Query: 363 GLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYYETFEFM 184
GL HRAKLDNN L FA LE+V IETIE+G MTKDLA CIKG+ NV+RSDY TFEFM
Sbjct: 339 GLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFM 398
Query: 183 DKLAENLKVALGQ 145
DKL ENLK+ L Q
Sbjct: 399 DKLGENLKIKLAQ 411
>BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein
protein.
Length = 414
Score = 342 bits (841), Expect = 7e-94
Identities = 156/193 (80%), Positives = 170/193 (88%)
Frame = -2
Query: 723 YDGRFKDIFQDIYDREYKXQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACXNYDGDVQS 544
YDGRFKDIFQ+IYD++YK QFE IWYEHRLIDDMVA AMKSEGGF+WAC NYDGDVQS
Sbjct: 219 YDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQS 278
Query: 543 DSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFAWTR 364
DSVAQGYGSLG+MTSVL+CPDGKTVEAEAAHGTVTRH+R YQ+G+ETSTNPIASIFAWTR
Sbjct: 279 DSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTR 338
Query: 363 GLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYYETFEFM 184
GL HRAKLDNN L FA LE+V IETIE+G MTKDLA CIKG+ NV+RSDY TFEFM
Sbjct: 339 GLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFM 398
Query: 183 DKLAENLKVALGQ 145
DKL ENLK+ L Q
Sbjct: 399 DKLGENLKIKLAQ 411
>BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein.
Length = 414
Score = 342 bits (841), Expect = 7e-94
Identities = 156/193 (80%), Positives = 170/193 (88%)
Frame = -2
Query: 723 YDGRFKDIFQDIYDREYKXQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACXNYDGDVQS 544
YDGRFKDIFQ+IYD++YK QFE IWYEHRLIDDMVA AMKSEGGF+WAC NYDGDVQS
Sbjct: 219 YDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQS 278
Query: 543 DSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFAWTR 364
DSVAQGYGSLG+MTSVL+CPDGKTVEAEAAHGTVTRH+R YQ+G+ETSTNPIASIFAWTR
Sbjct: 279 DSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTR 338
Query: 363 GLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYYETFEFM 184
GL HRAKLDNN L FA LE+V IETIE+G MTKDLA CIKG+ NV+RSDY TFEFM
Sbjct: 339 GLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFM 398
Query: 183 DKLAENLKVALGQ 145
DKL ENLK+ L Q
Sbjct: 399 DKLGENLKIKLAQ 411
>AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 342 bits (841), Expect = 7e-94
Identities = 156/193 (80%), Positives = 170/193 (88%)
Frame = -2
Query: 723 YDGRFKDIFQDIYDREYKXQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACXNYDGDVQS 544
YDGRFKDIFQ+IYD++YK QFE IWYEHRLIDDMVA AMKSEGGF+WAC NYDGDVQS
Sbjct: 219 YDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQS 278
Query: 543 DSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFAWTR 364
DSVAQGYGSLG+MTSVL+CPDGKTVEAEAAHGTVTRH+R YQ+G+ETSTNPIASIFAWTR
Sbjct: 279 DSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTR 338
Query: 363 GLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYYETFEFM 184
GL HRAKLDNN L FA LE+V IETIE+G MTKDLA CIKG+ NV+RSDY TFEFM
Sbjct: 339 GLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFM 398
Query: 183 DKLAENLKVALGQ 145
DKL ENLK+ L Q
Sbjct: 399 DKLGENLKIKLAQ 411
>AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein.
Length = 414
Score = 342 bits (841), Expect = 7e-94
Identities = 156/193 (80%), Positives = 170/193 (88%)
Frame = -2
Query: 723 YDGRFKDIFQDIYDREYKXQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACXNYDGDVQS 544
YDGRFKDIFQ+IYD++YK QFE IWYEHRLIDDMVA AMKSEGGF+WAC NYDGDVQS
Sbjct: 219 YDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQS 278
Query: 543 DSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFAWTR 364
DSVAQGYGSLG+MTSVL+CPDGKTVEAEAAHGTVTRH+R YQ+G+ETSTNPIASIFAWTR
Sbjct: 279 DSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTR 338
Query: 363 GLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYYETFEFM 184
GL HRAKLDNN L FA LE+V IETIE+G MTKDLA CIKG+ NV+RSDY TFEFM
Sbjct: 339 GLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFM 398
Query: 183 DKLAENLKVALGQ 145
DKL ENLK+ L Q
Sbjct: 399 DKLGENLKIKLAQ 411
>BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenase 1
(NADP+), soluble protein.
Length = 414
Score = 341 bits (838), Expect = 2e-93
Identities = 155/193 (80%), Positives = 170/193 (88%)
Frame = -2
Query: 723 YDGRFKDIFQDIYDREYKXQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACXNYDGDVQS 544
YDGRFKDIFQ+IYD++YK QFE IWYEHRLIDDMVA AMKSEGGF+WAC NYDGDVQS
Sbjct: 219 YDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQS 278
Query: 543 DSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFAWTR 364
DSVAQGYGSLG+MTSVL+CPDGKTVEAE+AHGTVTRH+R YQ+G+ETSTNPIASIFAWTR
Sbjct: 279 DSVAQGYGSLGMMTSVLVCPDGKTVEAESAHGTVTRHYRMYQKGQETSTNPIASIFAWTR 338
Query: 363 GLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYYETFEFM 184
GL HRAKLDNN L FA LE+V IETIE+G MTKDLA CIKG+ NV+RSDY TFEFM
Sbjct: 339 GLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFM 398
Query: 183 DKLAENLKVALGQ 145
DKL ENLK+ L Q
Sbjct: 399 DKLGENLKIKLAQ 411
>CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 339 bits (834), Expect = 5e-93
Identities = 155/193 (80%), Positives = 169/193 (87%)
Frame = -2
Query: 723 YDGRFKDIFQDIYDREYKXQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACXNYDGDVQS 544
YDGRFKDIFQ+IYD++YK QFE IWYEHRLIDDMVA AMKSEGGF+WAC NYDGDVQS
Sbjct: 219 YDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQS 278
Query: 543 DSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFAWTR 364
DSVAQGYGSLG+MTSVL+CPDGKTVEAEAAHGTVTRH+R YQ+G+ETSTNPIASIFAWTR
Sbjct: 279 DSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTR 338
Query: 363 GLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYYETFEFM 184
GL HRAKLDNN L FA LE+V IETIE+G MTK LA CIKG+ NV+RSDY TFEFM
Sbjct: 339 GLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKGLAACIKGLPNVQRSDYLNTFEFM 398
Query: 183 DKLAENLKVALGQ 145
DKL ENLK+ L Q
Sbjct: 399 DKLGENLKIKLAQ 411
>AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 337 bits (828), Expect = 3e-92
Identities = 154/193 (79%), Positives = 169/193 (87%)
Frame = -2
Query: 723 YDGRFKDIFQDIYDREYKXQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACXNYDGDVQS 544
YDGRFKDIFQ+IYD++YK QFE IWYEHRLIDDMVA AMKSEGGF+WAC NYDGDVQS
Sbjct: 219 YDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQS 278
Query: 543 DSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFAWTR 364
DSVAQGYGSLG+MTSVL+CPDGKTVEAEAAHGTVTRH+R YQ+G+ETSTN IASIFAWTR
Sbjct: 279 DSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNLIASIFAWTR 338
Query: 363 GLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYYETFEFM 184
GL HRAKLDNN L FA LE+V IETIE+G MTKDLA CI+G+ NV+RSDY TFEFM
Sbjct: 339 GLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIRGLPNVQRSDYLNTFEFM 398
Query: 183 DKLAENLKVALGQ 145
DKL ENLK+ L Q
Sbjct: 399 DKLGENLKIKLAQ 411
>DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenase 1
protein.
Length = 371
Score = 328 bits (806), Expect = 1e-89
Identities = 149/182 (81%), Positives = 162/182 (89%)
Frame = -2
Query: 723 YDGRFKDIFQDIYDREYKXQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACXNYDGDVQS 544
YDGRFKDIFQ+IYD++YK QFE IWYEHRLIDDMVA AMKSEGGF+WAC NYDGDVQS
Sbjct: 190 YDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQS 249
Query: 543 DSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFAWTR 364
DSVAQGYGSLG+MTSVL+CPDGKTVEAEAAHGTVTRH+R YQ+G+ETSTNPIASIFAWTR
Sbjct: 250 DSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTR 309
Query: 363 GLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYYETFEFM 184
GL HRAKLDNN L FA LE+V IETIE+G MTKDLA CIKG+ NV+RSDY TFEFM
Sbjct: 310 GLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFM 369
Query: 183 DK 178
DK
Sbjct: 370 DK 371
>X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase
(NADP+) protein.
Length = 452
Score = 300 bits (736), Expect = 4e-81
Identities = 135/194 (69%), Positives = 161/194 (82%), Gaps = 1/194 (0%)
Frame = -2
Query: 723 YDGRFKDIFQDIYDREYKXQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACXNYDGDVQS 544
YDGRFKDIFQ+I+D+ YK F+ IWYEHRLIDDMVA +KS GGFVWAC NYDGDVQS
Sbjct: 258 YDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQS 317
Query: 543 DSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFAWTR 364
D +AQG+GSLGLMTSVL+CPDGKT+EAEAAHGTVTRH+R +Q+G+ TSTNPIASIFAWTR
Sbjct: 318 DILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTR 377
Query: 363 GLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYY-ETFEF 187
GL HR KLD N L FA+ LEKVC+ET+ESG MTKDLA CI G++NVK ++++ T +F
Sbjct: 378 GLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTMDF 437
Query: 186 MDKLAENLKVALGQ 145
+D + NL ALG+
Sbjct: 438 LDTIKSNLDRALGR 451
>U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase
protein.
Length = 419
Score = 299 bits (734), Expect = 6e-81
Identities = 135/194 (69%), Positives = 161/194 (82%), Gaps = 1/194 (0%)
Frame = -2
Query: 723 YDGRFKDIFQDIYDREYKXQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACXNYDGDVQS 544
YDGRFKDIFQ+I+D+ YK F+ IWYEHRLIDDMVA +KS GGFVWAC NYDGDVQS
Sbjct: 225 YDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQS 284
Query: 543 DSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFAWTR 364
D +AQG+GSLGLMTSVL+CPDGKT+EAEAAHGTVTRH+R +Q+G+ TSTNPIASIFAWTR
Sbjct: 285 DILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTR 344
Query: 363 GLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYY-ETFEF 187
GL HR KLD N L FA+ LEKVC+ET+ESG MTKDLA CI G++NVK ++++ T +F
Sbjct: 345 GLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDF 404
Query: 186 MDKLAENLKVALGQ 145
+D + NL ALG+
Sbjct: 405 LDTIKSNLDRALGR 418
>BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 299 bits (734), Expect = 6e-81
Identities = 135/194 (69%), Positives = 161/194 (82%), Gaps = 1/194 (0%)
Frame = -2
Query: 723 YDGRFKDIFQDIYDREYKXQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACXNYDGDVQS 544
YDGRFKDIFQ+I+D+ YK F+ IWYEHRLIDDMVA +KS GGFVWAC NYDGDVQS
Sbjct: 258 YDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQS 317
Query: 543 DSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFAWTR 364
D +AQG+GSLGLMTSVL+CPDGKT+EAEAAHGTVTRH+R +Q+G+ TSTNPIASIFAWTR
Sbjct: 318 DILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTR 377
Query: 363 GLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYY-ETFEF 187
GL HR KLD N L FA+ LEKVC+ET+ESG MTKDLA CI G++NVK ++++ T +F
Sbjct: 378 GLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDF 437
Query: 186 MDKLAENLKVALGQ 145
+D + NL ALG+
Sbjct: 438 LDTIKSNLDRALGR 451
>BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 299 bits (734), Expect = 6e-81
Identities = 135/194 (69%), Positives = 161/194 (82%), Gaps = 1/194 (0%)
Frame = -2
Query: 723 YDGRFKDIFQDIYDREYKXQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACXNYDGDVQS 544
YDGRFKDIFQ+I+D+ YK F+ IWYEHRLIDDMVA +KS GGFVWAC NYDGDVQS
Sbjct: 258 YDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQS 317
Query: 543 DSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFAWTR 364
D +AQG+GSLGLMTSVL+CPDGKT+EAEAAHGTVTRH+R +Q+G+ TSTNPIASIFAWTR
Sbjct: 318 DILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTR 377
Query: 363 GLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYY-ETFEF 187
GL HR KLD N L FA+ LEKVC+ET+ESG MTKDLA CI G++NVK ++++ T +F
Sbjct: 378 GLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDF 437
Query: 186 MDKLAENLKVALGQ 145
+D + NL ALG+
Sbjct: 438 LDTIKSNLDRALGR 451
>AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial precursor variant protein.
Length = 452
Score = 297 bits (730), Expect = 2e-80
Identities = 134/194 (69%), Positives = 161/194 (82%), Gaps = 1/194 (0%)
Frame = -2
Query: 723 YDGRFKDIFQDIYDREYKXQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACXNYDGDVQS 544
YDGRFKDIFQ+I+D+ Y+ F+ IWYEHRLIDDMVA +KS GGFVWAC NYDGDVQS
Sbjct: 258 YDGRFKDIFQEIFDKHYETDFDKNKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQS 317
Query: 543 DSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFAWTR 364
D +AQG+GSLGLMTSVL+CPDGKT+EAEAAHGTVTRH+R +Q+G+ TSTNPIASIFAWTR
Sbjct: 318 DILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTR 377
Query: 363 GLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYY-ETFEF 187
GL HR KLD N L FA+ LEKVC+ET+ESG MTKDLA CI G++NVK ++++ T +F
Sbjct: 378 GLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDF 437
Query: 186 MDKLAENLKVALGQ 145
+D + NL ALG+
Sbjct: 438 LDTIKSNLDRALGR 451
>AF197566-1|AAG43470.1| 127|Homo sapiens NADP+-specific isocitrate
dehydrogenase protein.
Length = 127
Score = 128 bits (308), Expect = 3e-29
Identities = 61/89 (68%), Positives = 69/89 (77%)
Frame = -2
Query: 411 KETSTNPIASIFAWTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLAICIKG 232
+E STNPIASIFAWTRGL RAK DNN L FA LE+VCIETIE+G MTKDLA CIKG
Sbjct: 1 QEISTNPIASIFAWTRGLALRAKTDNNKELAFFANALEEVCIETIEAGFMTKDLAACIKG 60
Query: 231 MNNVKRSDYYETFEFMDKLAENLKVALGQ 145
+ + + SDY TFEFM+KL ENLK+ L Q
Sbjct: 61 LPSAQCSDYLNTFEFMEKLGENLKIKLAQ 89
>U62389-1|AAB17375.1| 154|Homo sapiens putative cytosolic
NADP-dependent isocitrate dehydrogenase protein.
Length = 154
Score = 69.3 bits (162), Expect = 1e-11
Identities = 28/35 (80%), Positives = 31/35 (88%)
Frame = -2
Query: 723 YDGRFKDIFQDIYDREYKXQFEDAGIWYEHRLIDD 619
YDGRFKDIFQ+IYD++YK QFE IWYEHRLIDD
Sbjct: 120 YDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDD 154
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 100,764,406
Number of Sequences: 237096
Number of extensions: 2022058
Number of successful extensions: 3074
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 2996
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3068
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8511181328
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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