Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P02_F_J06
(819 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein. 303 4e-82
BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenas... 303 4e-82
BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein. 303 4e-82
AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitr... 303 4e-82
AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitra... 303 4e-82
AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein. 303 4e-82
CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein. 303 6e-82
CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein. 302 8e-82
BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein pr... 301 1e-81
X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase... 283 7e-76
BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenas... 283 7e-76
BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenas... 283 7e-76
AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenas... 283 7e-76
DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenas... 264 3e-70
U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase ... 238 2e-62
U62389-1|AAB17375.1| 154|Homo sapiens putative cytosolic NADP-d... 138 2e-32
>CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 303 bits (745), Expect = 4e-82
Identities = 140/198 (70%), Positives = 167/198 (84%), Gaps = 2/198 (1%)
Frame = +3
Query: 228 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 407
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 408 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 587
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 588 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVXHXY-KGAGVXLAMF 761
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++ H + +G GV + M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 762 NTDASIIDXAHSSFKFAL 815
N D SI D AHSSF+ AL
Sbjct: 184 NQDKSIEDFAHSSFQMAL 201
>BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenase 1
(NADP+), soluble protein.
Length = 414
Score = 303 bits (745), Expect = 4e-82
Identities = 140/198 (70%), Positives = 167/198 (84%), Gaps = 2/198 (1%)
Frame = +3
Query: 228 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 407
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 408 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 587
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 588 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVXHXY-KGAGVXLAMF 761
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++ H + +G GV + M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 762 NTDASIIDXAHSSFKFAL 815
N D SI D AHSSF+ AL
Sbjct: 184 NQDKSIEDFAHSSFQMAL 201
>BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein.
Length = 414
Score = 303 bits (745), Expect = 4e-82
Identities = 140/198 (70%), Positives = 167/198 (84%), Gaps = 2/198 (1%)
Frame = +3
Query: 228 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 407
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 408 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 587
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 588 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVXHXY-KGAGVXLAMF 761
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++ H + +G GV + M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 762 NTDASIIDXAHSSFKFAL 815
N D SI D AHSSF+ AL
Sbjct: 184 NQDKSIEDFAHSSFQMAL 201
>AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 303 bits (745), Expect = 4e-82
Identities = 140/198 (70%), Positives = 167/198 (84%), Gaps = 2/198 (1%)
Frame = +3
Query: 228 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 407
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 408 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 587
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 588 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVXHXY-KGAGVXLAMF 761
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++ H + +G GV + M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 762 NTDASIIDXAHSSFKFAL 815
N D SI D AHSSF+ AL
Sbjct: 184 NQDKSIEDFAHSSFQMAL 201
>AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 303 bits (745), Expect = 4e-82
Identities = 140/198 (70%), Positives = 167/198 (84%), Gaps = 2/198 (1%)
Frame = +3
Query: 228 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 407
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 408 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 587
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 588 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVXHXY-KGAGVXLAMF 761
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++ H + +G GV + M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 762 NTDASIIDXAHSSFKFAL 815
N D SI D AHSSF+ AL
Sbjct: 184 NQDKSIEDFAHSSFQMAL 201
>AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein.
Length = 414
Score = 303 bits (745), Expect = 4e-82
Identities = 140/198 (70%), Positives = 167/198 (84%), Gaps = 2/198 (1%)
Frame = +3
Query: 228 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 407
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 408 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 587
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 588 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVXHXY-KGAGVXLAMF 761
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++ H + +G GV + M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 762 NTDASIIDXAHSSFKFAL 815
N D SI D AHSSF+ AL
Sbjct: 184 NQDKSIEDFAHSSFQMAL 201
>CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 303 bits (743), Expect = 6e-82
Identities = 139/198 (70%), Positives = 168/198 (84%), Gaps = 2/198 (1%)
Frame = +3
Query: 228 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 407
KI G VV++ GDEMTRIIW+LIKEKLI+P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIIPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 408 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 587
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 588 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVXHXY-KGAGVXLAMF 761
W +PIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++ H + +G GV + M+
Sbjct: 124 WVEPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 762 NTDASIIDXAHSSFKFAL 815
N D SI D AHSSF+ AL
Sbjct: 184 NQDKSIEDFAHSSFQMAL 201
>CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 302 bits (742), Expect = 8e-82
Identities = 139/198 (70%), Positives = 167/198 (84%), Gaps = 2/198 (1%)
Frame = +3
Query: 228 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 407
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 408 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 587
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 588 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVXHXY-KGAGVXLAMF 761
W KPIIIGRHA+ DQY+ATDFVVPG G +E+ + P G + + ++ H + +G GV + M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEMTYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 762 NTDASIIDXAHSSFKFAL 815
N D SI D AHSSF+ AL
Sbjct: 184 NQDKSIEDFAHSSFQMAL 201
>BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein
protein.
Length = 414
Score = 301 bits (740), Expect = 1e-81
Identities = 140/198 (70%), Positives = 166/198 (83%), Gaps = 2/198 (1%)
Frame = +3
Query: 228 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 407
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 408 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 587
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 588 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVXHXYK-GAGVXLAMF 761
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++ H + G GV + M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNSEGGGGVAMGMY 183
Query: 762 NTDASIIDXAHSSFKFAL 815
N D SI D AHSSF+ AL
Sbjct: 184 NQDKSIEDFAHSSFQMAL 201
>X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase
(NADP+) protein.
Length = 452
Score = 283 bits (693), Expect = 7e-76
Identities = 134/202 (66%), Positives = 157/202 (77%), Gaps = 2/202 (0%)
Frame = +3
Query: 216 YNMSKIK-AGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTI 392
Y +IK A PVV++ GDEMTRIIW IKEKLILP +DI+L +DLG+ NRD+TDDQVTI
Sbjct: 39 YADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTI 98
Query: 393 DCAEAIKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIP 572
D A A +KY+V +KCATITPDE RVEEFKLKKMWKSPNGTIRNILGGTVFRE IICKNIP
Sbjct: 99 DSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIP 158
Query: 573 RLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESGEAIKH-VXHXYKGAGVX 749
RLV GW KPI IGRHAH DQYKATDFV AGT +++F P+ G +K + + GV
Sbjct: 159 RLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVG 218
Query: 750 LAMFNTDASIIDXAHSSFKFAL 815
+ M+NTD SI AHS F++A+
Sbjct: 219 MGMYNTDESISGFAHSCFQYAI 240
>BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 283 bits (693), Expect = 7e-76
Identities = 134/202 (66%), Positives = 157/202 (77%), Gaps = 2/202 (0%)
Frame = +3
Query: 216 YNMSKIK-AGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTI 392
Y +IK A PVV++ GDEMTRIIW IKEKLILP +DI+L +DLG+ NRD+TDDQVTI
Sbjct: 39 YADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTI 98
Query: 393 DCAEAIKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIP 572
D A A +KY+V +KCATITPDE RVEEFKLKKMWKSPNGTIRNILGGTVFRE IICKNIP
Sbjct: 99 DSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIP 158
Query: 573 RLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESGEAIKH-VXHXYKGAGVX 749
RLV GW KPI IGRHAH DQYKATDFV AGT +++F P+ G +K + + GV
Sbjct: 159 RLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVG 218
Query: 750 LAMFNTDASIIDXAHSSFKFAL 815
+ M+NTD SI AHS F++A+
Sbjct: 219 MGMYNTDESISGFAHSCFQYAI 240
>BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 283 bits (693), Expect = 7e-76
Identities = 134/202 (66%), Positives = 157/202 (77%), Gaps = 2/202 (0%)
Frame = +3
Query: 216 YNMSKIK-AGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTI 392
Y +IK A PVV++ GDEMTRIIW IKEKLILP +DI+L +DLG+ NRD+TDDQVTI
Sbjct: 39 YADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTI 98
Query: 393 DCAEAIKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIP 572
D A A +KY+V +KCATITPDE RVEEFKLKKMWKSPNGTIRNILGGTVFRE IICKNIP
Sbjct: 99 DSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIP 158
Query: 573 RLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESGEAIKH-VXHXYKGAGVX 749
RLV GW KPI IGRHAH DQYKATDFV AGT +++F P+ G +K + + GV
Sbjct: 159 RLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVG 218
Query: 750 LAMFNTDASIIDXAHSSFKFAL 815
+ M+NTD SI AHS F++A+
Sbjct: 219 MGMYNTDESISGFAHSCFQYAI 240
>AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial precursor variant protein.
Length = 452
Score = 283 bits (693), Expect = 7e-76
Identities = 134/202 (66%), Positives = 157/202 (77%), Gaps = 2/202 (0%)
Frame = +3
Query: 216 YNMSKIK-AGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTI 392
Y +IK A PVV++ GDEMTRIIW IKEKLILP +DI+L +DLG+ NRD+TDDQVTI
Sbjct: 39 YADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTI 98
Query: 393 DCAEAIKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIP 572
D A A +KY+V +KCATITPDE RVEEFKLKKMWKSPNGTIRNILGGTVFRE IICKNIP
Sbjct: 99 DSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIP 158
Query: 573 RLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESGEAIKH-VXHXYKGAGVX 749
RLV GW KPI IGRHAH DQYKATDFV AGT +++F P+ G +K + + GV
Sbjct: 159 RLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVG 218
Query: 750 LAMFNTDASIIDXAHSSFKFAL 815
+ M+NTD SI AHS F++A+
Sbjct: 219 MGMYNTDESISGFAHSCFQYAI 240
>DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenase 1
protein.
Length = 371
Score = 264 bits (646), Expect = 3e-70
Identities = 121/172 (70%), Positives = 145/172 (84%), Gaps = 2/172 (1%)
Frame = +3
Query: 306 LILPFLDIELHVYDLGMENRDKTDDQVTIDCAEAIKKYNVGIKCATITPDEKRVEEFKLK 485
LI P+++++LH YDLG+ENRD T+DQVT D AEAIKK+NVG+KCATITPDEKRVEEFKLK
Sbjct: 1 LIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLK 60
Query: 486 KMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGA 665
+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+GW KPIIIGRHA+ DQY+ATDFVVPG
Sbjct: 61 QMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGP 120
Query: 666 GTLEIIFKPESG-EAIKHVXHXY-KGAGVXLAMFNTDASIIDXAHSSFKFAL 815
G +EI + P G + + ++ H + +G GV + M+N D SI D AHSSF+ AL
Sbjct: 121 GKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMAL 172
>U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase
protein.
Length = 419
Score = 238 bits (582), Expect = 2e-62
Identities = 109/166 (65%), Positives = 129/166 (77%), Gaps = 1/166 (0%)
Frame = +3
Query: 321 LDIELHVYDLGMENRDKTDDQVTIDCAEAIKKYNVGIKCATITPDEKRVEEFKLKKMWKS 500
LD++L +DLG+ NRD+TDDQVTID A A +KY+V +KCATITPDE RVEEFKLKKMWKS
Sbjct: 42 LDVQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKS 101
Query: 501 PNGTIRNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEI 680
PNGTIRNI GGTVFRE IICKNIPRLV GW KPI IGRHAH DQYKATDFV AGT ++
Sbjct: 102 PNGTIRNIHGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKM 161
Query: 681 IFKPESGEAIKH-VXHXYKGAGVXLAMFNTDASIIDXAHSSFKFAL 815
+F P+ G +K + + GV + M+NTD SI AHS F++A+
Sbjct: 162 VFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAI 207
>U62389-1|AAB17375.1| 154|Homo sapiens putative cytosolic
NADP-dependent isocitrate dehydrogenase protein.
Length = 154
Score = 138 bits (335), Expect = 2e-32
Identities = 65/102 (63%), Positives = 79/102 (77%), Gaps = 2/102 (1%)
Frame = +3
Query: 516 RNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPE 695
RNILGGTVF EAIICKNIPRLV+GW KPIIIGRHA+ DQY+ATDFVVPG G +EI + P
Sbjct: 1 RNILGGTVFXEAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPS 60
Query: 696 SG-EAIKHVXHXY-KGAGVXLAMFNTDASIIDXAHSSFKFAL 815
G + + ++ H + +G GV + M+N D SI D AHSSF+ AL
Sbjct: 61 DGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMAL 102
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 116,770,883
Number of Sequences: 237096
Number of extensions: 2574756
Number of successful extensions: 3950
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 3826
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3934
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10203625794
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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