Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P02_F_C04
(623 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC006294-1|AAH06294.1| 270|Homo sapiens hydroxysteroid (17-beta... 85 1e-16
BC006283-1|AAH06283.1| 270|Homo sapiens hydroxysteroid (17-beta... 85 1e-16
AY358430-1|AAQ88796.1| 270|Homo sapiens ATGT502 protein. 85 1e-16
AF126781-1|AAF06940.1| 270|Homo sapiens retinal short-chain deh... 85 1e-16
U31875-1|AAA82048.1| 280|Homo sapiens Hep27 protein protein. 85 3e-16
BC007339-1|AAH07339.2| 271|Homo sapiens DHRS2 protein protein. 85 3e-16
BC002786-1|AAH02786.1| 300|Homo sapiens dehydrogenase/reductase... 85 3e-16
AF244132-1|AAG33703.1| 280|Homo sapiens short-chain alcohol deh... 85 3e-16
AK222857-1|BAD96577.1| 280|Homo sapiens dehydrogenase/reductase... 82 2e-15
BC007337-1|AAH07337.1| 339|Homo sapiens dehydrogenase/reductase... 75 2e-13
BC000637-1|AAH00637.1| 339|Homo sapiens dehydrogenase/reductase... 75 2e-13
AY359031-1|AAQ89390.1| 289|Homo sapiens oxidoreductase/S-2 H pr... 75 2e-13
AF151844-1|AAD34081.1| 339|Homo sapiens CGI-86 protein protein. 75 2e-13
AF126782-1|AAF06941.1| 289|Homo sapiens retinal short-chain deh... 75 2e-13
AK001870-1|BAA91953.1| 278|Homo sapiens protein ( Homo sapiens ... 74 5e-13
DQ344810-1|ABD75823.1| 278|Homo sapiens NADP(H)-dependent retin... 73 6e-13
BC003019-1|AAH03019.1| 278|Homo sapiens dehydrogenase/reductase... 73 6e-13
BC002529-1|AAH02529.1| 303|Homo sapiens peroxisomal trans-2-eno... 73 6e-13
AY358638-1|AAQ89001.1| 278|Homo sapiens SCAD-SRL protein. 73 6e-13
AF232009-1|AAF69798.1| 303|Homo sapiens peroxisomal trans 2-eno... 73 6e-13
AF212234-1|AAK14920.1| 322|Homo sapiens HPDHase protein. 73 6e-13
AC010686-2|AAY14657.1| 303|Homo sapiens unknown protein. 73 6e-13
AB045131-1|BAB18775.1| 260|Homo sapiens NADPH-dependent retinol... 73 6e-13
AJ250303-1|CAB89810.1| 303|Homo sapiens peroxisomal 2-enoyl-CoA... 73 8e-13
AF064256-1|AAQ13444.1| 278|Homo sapiens Hep27-like protein prot... 73 1e-12
AF044127-1|AAD02292.1| 260|Homo sapiens peroxisomal short-chain... 73 1e-12
BC095414-1|AAH95414.1| 245|Homo sapiens 3-hydroxybutyrate dehyd... 71 4e-12
BC001953-1|AAH01953.1| 245|Homo sapiens 3-hydroxybutyrate dehyd... 71 4e-12
AF164790-1|AAF80754.1| 245|Homo sapiens oxidoreductase UCPA pro... 71 4e-12
AY358841-1|AAQ89200.1| 245|Homo sapiens GRLD6308 protein. 69 1e-11
BC033650-1|AAH33650.1| 237|Homo sapiens carbonyl reductase 4 pr... 68 2e-11
BC021973-1|AAH21973.1| 237|Homo sapiens carbonyl reductase 4 pr... 68 2e-11
CR457124-1|CAG33405.1| 325|Homo sapiens DKFZp566O084 protein. 66 1e-10
BC009679-1|AAH09679.1| 325|Homo sapiens dehydrogenase/reductase... 66 1e-10
BC004126-1|AAH04126.1| 325|Homo sapiens dehydrogenase/reductase... 66 1e-10
AY358498-1|AAQ88862.1| 310|Homo sapiens DFIT212 protein. 66 1e-10
AF151851-1|AAD34088.1| 291|Homo sapiens CGI-93 protein protein. 66 1e-10
AK027337-1|BAB55045.1| 179|Homo sapiens protein ( Homo sapiens ... 65 2e-10
BC000663-1|AAH00663.2| 230|Homo sapiens dehydrogenase/reductase... 62 2e-09
X63657-1|CAA45197.1| 332|Homo sapiens FVT1 protein. 60 6e-09
BT006782-1|AAP35428.1| 332|Homo sapiens follicular lymphoma var... 60 6e-09
BC008797-1|AAH08797.1| 332|Homo sapiens follicular lymphoma var... 60 6e-09
BC104218-1|AAI04219.1| 330|Homo sapiens hydroxysteroid dehydrog... 60 8e-09
AY028377-1|AAK16927.1| 309|Homo sapiens steroid dehydrogenase-l... 60 8e-09
AK074878-1|BAC11262.1| 330|Homo sapiens protein ( Homo sapiens ... 60 8e-09
AF237684-1|AAK15047.1| 309|Homo sapiens steroid dehydrogenase-l... 60 8e-09
BC036001-1|AAH36001.1| 300|Homo sapiens hydroxysteroid (17-beta... 59 1e-08
BC021673-1|AAH21673.1| 300|Homo sapiens hydroxysteroid (17-beta... 59 1e-08
BC016367-1|AAH16367.1| 300|Homo sapiens hydroxysteroid (17-beta... 59 1e-08
BC014327-1|AAH14327.1| 300|Homo sapiens hydroxysteroid (17-beta... 59 1e-08
AY358553-1|AAQ88917.1| 300|Homo sapiens KFLL207 protein. 59 1e-08
AK075348-1|BAC11560.1| 300|Homo sapiens protein ( Homo sapiens ... 59 1e-08
AF273056-1|AAM44459.1| 300|Homo sapiens CTCL tumor antigen HD-C... 59 1e-08
AF139841-1|AAP97273.1| 244|Homo sapiens carbonyl reductase II p... 59 1e-08
AF126780-1|AAF06939.1| 300|Homo sapiens retinal short-chain deh... 59 1e-08
BC106917-1|AAI06918.1| 330|Homo sapiens hydroxysteroid dehydrog... 58 2e-08
BC104219-1|AAI04220.1| 330|Homo sapiens hydroxysteroid dehydrog... 58 2e-08
BC018084-1|AAH18084.2| 330|Homo sapiens hydroxysteroid dehydrog... 58 3e-08
BT006881-1|AAP35527.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 57 4e-08
BC003018-1|AAH03018.1| 243|Homo sapiens Unknown (protein for IM... 57 4e-08
BC001470-1|AAH01470.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 57 4e-08
AF515625-1|AAM54026.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 57 4e-08
AF515624-1|AAO15991.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 57 4e-08
AF515623-1|AAN59786.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 57 4e-08
AF113123-1|AAF14864.1| 244|Homo sapiens carbonyl reductase prot... 57 4e-08
AB013846-1|BAB64299.1| 244|Homo sapiens kidney dicarbonyl reduc... 57 4e-08
M93107-1|AAA58352.1| 343|Homo sapiens (R)-3-hydroxybutyrate deh... 57 6e-08
M76665-1|AAC31757.1| 292|Homo sapiens 11-beta-hydroxysteroid de... 57 6e-08
L76465-1|AAA89175.1| 266|Homo sapiens NAD+-dependent 15-hydroxy... 57 6e-08
J05594-1|AAA89174.1| 266|Homo sapiens NAD+-dependent 15-hydroxy... 57 6e-08
DQ903072-1|ABI75347.1| 266|Homo sapiens hydroxyprostaglandin de... 57 6e-08
BC019317-1|AAH19317.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 57 6e-08
BC018986-1|AAH18986.1| 266|Homo sapiens hydroxyprostaglandin de... 57 6e-08
BC012593-1|AAH12593.1| 292|Homo sapiens hydroxysteroid (11-beta... 57 6e-08
BC011964-1|AAH11964.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 57 6e-08
BC005844-1|AAH05844.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 57 6e-08
AY044084-1|AAK83653.1| 292|Homo sapiens 11-beta hydroxysteroid ... 57 6e-08
AL031316-4|CAI20063.1| 292|Homo sapiens hydroxysteroid (11-beta... 57 6e-08
AL022398-8|CAA18541.2| 292|Homo sapiens hydroxysteroid (11-beta... 57 6e-08
BC008650-1|AAH08650.1| 300|Homo sapiens HSD17B11 protein protein. 56 8e-08
BC015943-1|AAH15943.1| 313|Homo sapiens DHRS1 protein protein. 55 2e-07
BC014057-1|AAH14057.1| 313|Homo sapiens DHRS1 protein protein. 55 2e-07
AK058159-1|BAB71694.1| 313|Homo sapiens protein ( Homo sapiens ... 55 2e-07
AF418205-1|AAN32660.1| 313|Homo sapiens dehydrogenase/reductase... 55 2e-07
U26726-1|AAC50356.1| 405|Homo sapiens 11-beta-hydroxysteroid de... 54 3e-07
EF694683-1|ABS29267.1| 405|Homo sapiens hydroxysteroid (11-beta... 54 3e-07
BC064536-1|AAH64536.1| 405|Homo sapiens hydroxysteroid (11-beta... 54 3e-07
BC036780-1|AAH36780.1| 405|Homo sapiens hydroxysteroid (11-beta... 54 3e-07
X87176-1|CAA60643.1| 736|Homo sapiens 17beta-hydroxysteroid deh... 54 4e-07
U14631-1|AAA91969.1| 405|Homo sapiens 11 beta-hydroxysteroid de... 54 4e-07
BC003098-1|AAH03098.1| 736|Homo sapiens hydroxysteroid (17-beta... 54 4e-07
AF057740-1|AAD08652.1| 736|Homo sapiens 17-beta-hydroxysteroid ... 54 4e-07
U27317-1|AAB48544.1| 405|Homo sapiens 11 beta-hydroxysteroid de... 53 7e-07
BC095451-1|AAH95451.1| 418|Homo sapiens hydroxysteroid dehydrog... 52 1e-06
AY313894-1|AAP83166.1| 315|Homo sapiens short-chain dehydrogena... 52 1e-06
AY268352-1|AAP42286.1| 286|Homo sapiens short-chain dehydrogena... 52 1e-06
AY093428-1|AAM14670.1| 418|Homo sapiens hydroxysteroid dehydrog... 52 1e-06
AL162732-1|CAM17152.1| 418|Homo sapiens hydroxysteroid dehydrog... 52 1e-06
CR457309-1|CAG33590.1| 173|Homo sapiens DHRS6 protein. 52 2e-06
BC037277-1|AAH37277.1| 173|Homo sapiens BDH2 protein protein. 52 2e-06
AK023323-1|BAB14526.1| 173|Homo sapiens protein ( Homo sapiens ... 52 2e-06
DQ325464-1|ABC61320.1| 244|Homo sapiens NADP(H)-dependent retin... 50 5e-06
BC002731-1|AAH02731.2| 260|Homo sapiens short-chain dehydrogena... 49 1e-05
AY358712-1|AAQ89074.1| 260|Homo sapiens ARPG836 protein. 49 1e-05
Z97054-8|CAI42653.1| 261|Homo sapiens hydroxysteroid (17-beta) ... 48 3e-05
U96132-1|AAC51812.1| 261|Homo sapiens amyloid beta-peptide bind... 48 3e-05
U73514-1|AAB68958.1| 261|Homo sapiens short-chain alcohol dehyd... 48 3e-05
L40802-1|AAC41917.1| 387|Homo sapiens 17-hydroxysteroid dehydro... 48 3e-05
L11708-1|AAA03562.1| 387|Homo sapiens 17 beta hydroxysteroid de... 48 3e-05
CR456723-1|CAG33004.1| 261|Homo sapiens HADH2 protein. 48 3e-05
BC059170-1|AAH59170.1| 387|Homo sapiens hydroxysteroid (17-beta... 48 3e-05
BC009581-1|AAH09581.1| 387|Homo sapiens hydroxysteroid (17-beta... 48 3e-05
BC000372-1|AAH00372.1| 261|Homo sapiens hydroxysteroid (17-beta... 48 3e-05
AY325910-1|AAP78485.1| 387|Homo sapiens hydroxysteroid (17-beta... 48 3e-05
AY092415-1|AAM18189.1| 196|Homo sapiens endoplasmic reticulum-a... 48 3e-05
AK223001-1|BAD96721.1| 387|Homo sapiens hydroxysteroid (17-beta... 48 3e-05
AF069134-1|AAC39900.1| 261|Homo sapiens putative short-chain ty... 48 3e-05
AF037438-1|AAC16419.1| 261|Homo sapiens 17beta-hydroxysteroid d... 48 3e-05
AF035555-1|AAC15902.1| 261|Homo sapiens 17beta-hydroxysteroid d... 48 3e-05
X82460-1|CAA57843.1| 178|Homo sapiens 15-hydroxy prostaglandin ... 47 5e-05
U63296-1|AAB53034.1| 143|Homo sapiens 15-hydroxyprostaglandin d... 47 5e-05
AF229845-1|AAF63160.1| 311|Homo sapiens photoreceptor outer seg... 47 6e-05
BC002730-1|AAH02730.1| 302|Homo sapiens dehydrogenase/reductase... 45 3e-04
AL645761-1|CAI14999.1| 302|Homo sapiens dehydrogenase/reductase... 45 3e-04
AL513016-1|CAH74172.1| 302|Homo sapiens dehydrogenase/reductase... 45 3e-04
AK222593-1|BAD96313.1| 302|Homo sapiens dehydrogenase/reductase... 45 3e-04
AF179237-1|AAD55402.1| 302|Homo sapiens short-chain dehydrogena... 45 3e-04
AF061741-1|AAC63263.1| 302|Homo sapiens retinal short-chain deh... 45 3e-04
DQ088988-1|AAZ85982.1| 118|Homo sapiens DHRS4L2 isoform 2 protein. 44 4e-04
BC067131-1|AAH67131.1| 341|Homo sapiens retinol dehydrogenase 1... 44 4e-04
AY358270-1|AAQ88637.1| 341|Homo sapiens RDH10 protein. 44 4e-04
AF456765-1|AAN64747.1| 341|Homo sapiens retinol dehydrogenase 1... 44 4e-04
U43559-1|AAC50725.1| 318|Homo sapiens 11-cis retinol dehydrogen... 42 0.001
BC028298-1|AAH28298.1| 318|Homo sapiens retinol dehydrogenase 5... 42 0.001
AL645761-2|CAI15000.1| 147|Homo sapiens dehydrogenase/reductase... 42 0.001
AF037062-1|AAC09250.1| 318|Homo sapiens retinol dehydrogenase p... 42 0.001
AY358473-1|AAQ88837.1| 331|Homo sapiens RDH13 protein. 42 0.002
BC020710-1|AAH20710.1| 317|Homo sapiens hydroxysteroid (17-beta... 42 0.002
AF223225-1|AAF81017.1| 317|Homo sapiens 3-hydroxysteroid epimer... 42 0.002
AF016509-1|AAB67236.1| 317|Homo sapiens oxidoreductase protein. 42 0.002
AK075392-1|BAC11591.1| 331|Homo sapiens protein ( Homo sapiens ... 41 0.004
U78302-1|AAB88724.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 40 0.005
U49352-1|AAB09423.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 40 0.005
L26050-1|AAA67551.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 40 0.005
BC105082-1|AAI05083.1| 335|Homo sapiens 2,4-dienoyl CoA reducta... 40 0.005
BC105080-1|AAI05081.1| 335|Homo sapiens 2,4-dienoyl CoA reducta... 40 0.005
AC004612-1|AAC14671.1| 335|Homo sapiens 2,4-dienoyl-CoA reducta... 40 0.005
Z97054-7|CAI42652.1| 252|Homo sapiens hydroxysteroid (17-beta) ... 40 0.007
U89281-1|AAB88252.1| 317|Homo sapiens oxidative 3 alpha hydroxy... 40 0.007
BC064525-1|AAH64525.1| 309|Homo sapiens epidermal retinal dehyd... 40 0.007
BC037219-1|AAH37219.2| 309|Homo sapiens epidermal retinal dehyd... 40 0.007
BC008708-1|AAH08708.1| 252|Homo sapiens hydroxysteroid (17-beta... 40 0.007
AB083038-1|BAB91014.1| 309|Homo sapiens retinal short chain deh... 40 0.007
BT007239-1|AAP35903.1| 261|Homo sapiens hydroxysteroid (17-beta... 40 0.009
BC008185-1|AAH08185.1| 261|Homo sapiens hydroxysteroid (17-beta... 40 0.009
AL844527-12|CAI41840.1| 261|Homo sapiens hydroxysteroid (17-bet... 40 0.009
AL713971-6|CAI17657.1| 261|Homo sapiens hydroxysteroid (17-beta... 40 0.009
AL662824-24|CAI17616.1| 261|Homo sapiens hydroxysteroid (17-bet... 40 0.009
AL645940-10|CAI18068.1| 261|Homo sapiens hydroxysteroid (17-bet... 40 0.009
AL031228-10|CAC38444.1| 261|Homo sapiens hydroxysteroid (17-bet... 40 0.009
AF057034-1|AAC39922.1| 317|Homo sapiens sterol/retinol dehydrog... 39 0.012
U89717-1|AAB93668.1| 318|Homo sapiens 9-cis-retinol specific de... 39 0.017
AK057667-1|BAB71545.1| 231|Homo sapiens protein ( Homo sapiens ... 38 0.029
AF086735-1|AAC72923.1| 317|Homo sapiens retinol dehydrogenase p... 38 0.029
CR457180-1|CAG33461.1| 318|Homo sapiens RDH11 protein. 37 0.050
BC037302-1|AAH37302.1| 318|Homo sapiens retinol dehydrogenase 1... 37 0.050
BC026274-1|AAH26274.1| 318|Homo sapiens retinol dehydrogenase 1... 37 0.050
BC011727-1|AAH11727.1| 318|Homo sapiens RDH11 protein protein. 37 0.050
BC000112-1|AAH00112.1| 318|Homo sapiens retinol dehydrogenase 1... 37 0.050
AF395068-1|AAK72049.1| 318|Homo sapiens HCV core-binding protei... 37 0.050
AF167438-1|AAF89632.1| 318|Homo sapiens androgen-regulated shor... 37 0.050
AF151840-1|AAD34077.1| 318|Homo sapiens CGI-82 protein protein. 37 0.050
AB209653-1|BAD92890.1| 166|Homo sapiens dehydrogenase/reductase... 37 0.067
CR457356-1|CAG33637.1| 181|Homo sapiens MGC4172 protein. 36 0.088
AK026196-1|BAB15390.1| 181|Homo sapiens protein ( Homo sapiens ... 36 0.088
BC009881-1|AAH09881.1| 260|Homo sapiens retinol dehydrogenase 1... 36 0.15
AY268353-1|AAP42287.1| 199|Homo sapiens short-chain dehydrogena... 36 0.15
DQ426886-1|ABD90542.1| 171|Homo sapiens retinol dehydrogenase 1... 35 0.20
CR457145-1|CAG33426.1| 157|Homo sapiens PECR protein. 35 0.27
X13440-1|CAA31792.1| 328|Homo sapiens protein ( Human mRNA for ... 33 0.62
U34879-1|AAD05019.1| 328|Homo sapiens 17-beta-hydroxysteroid de... 33 0.62
M84472-1|AAB16942.1| 328|Homo sapiens 17-beta-hydroxysteroid de... 33 0.62
M36263-1|AAA35600.1| 328|Homo sapiens protein ( Human placental... 33 0.62
M27138-1|AAB16941.1| 328|Homo sapiens protein ( Human estradiol... 33 0.62
BC111935-1|AAI11936.1| 328|Homo sapiens hydroxysteroid (17-beta... 33 0.62
BC104752-1|AAI04753.1| 328|Homo sapiens hydroxysteroid (17-beta... 33 0.62
BC150182-1|AAI50183.1| 1192|Homo sapiens reticulon 4 protein. 32 1.4
AY123250-1|AAM64254.1| 986|Homo sapiens RTN4 isoform G protein. 32 1.4
AY123249-1|AAM64253.1| 986|Homo sapiens RTN4 isoform F protein. 32 1.4
AY123248-1|AAM64252.1| 986|Homo sapiens RTN4 isoform E protein. 32 1.4
AY123247-1|AAM64251.1| 986|Homo sapiens RTN4 isoform D protein. 32 1.4
AY123246-1|AAM64250.1| 986|Homo sapiens RTN4 isoform Ab protein. 32 1.4
AY123245-1|AAM64249.1| 986|Homo sapiens RTN4 isoform Aa protein. 32 1.4
AY102285-4|AAM64244.1| 986|Homo sapiens RNT4 protein. 32 1.4
AY102285-1|AAM64243.1| 1192|Homo sapiens RTN4 protein. 32 1.4
AY102279-1|AAM64248.1| 1192|Homo sapiens RTN4 isoform A protein. 32 1.4
AJ251383-1|CAB99248.1| 1192|Homo sapiens Nogo-A protein protein. 32 1.4
AF333336-1|AAK20831.1| 986|Homo sapiens testis specific reticul... 32 1.4
AF148537-1|AAG12176.1| 1192|Homo sapiens reticulon 4a protein. 32 1.4
AC092461-1|AAX93116.1| 818|Homo sapiens unknown protein. 32 1.4
AB073359-1|BAE45717.1| 294|Homo sapiens NOGO-A protein. 32 1.4
AB040462-1|BAB18927.1| 1192|Homo sapiens RTN-xL protein. 32 1.4
AB020693-1|BAA74909.2| 1233|Homo sapiens KIAA0886 protein protein. 32 1.4
Z97054-9|CAI42651.1| 169|Homo sapiens hydroxysteroid (17-beta) ... 31 2.5
AF069291-3|AAC62233.1| 188|Homo sapiens 2,4-dienoyl-CoA reducta... 30 7.6
>BC006294-1|AAH06294.1| 270|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 14 protein.
Length = 270
Score = 85.4 bits (202), Expect = 1e-16
Identities = 54/188 (28%), Positives = 91/188 (48%), Gaps = 1/188 (0%)
Frame = +2
Query: 62 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADL 241
+AGKVV GA++ + ++ + + ++ + I D+
Sbjct: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQE---LPGAVFILCDV 63
Query: 242 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNVRSIYYLTM 418
T+E D++ ++ +TI +G+LD +VNNAG E TS + +L+ N+ Y LT
Sbjct: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123
Query: 419 LAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVN 598
LA+P+L +S+G G + Y +K +V T+ +AL +P GVRVNC++
Sbjct: 124 LALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCIS 183
Query: 599 PXVILTEL 622
P I T L
Sbjct: 184 PGNIWTPL 191
>BC006283-1|AAH06283.1| 270|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 14 protein.
Length = 270
Score = 85.4 bits (202), Expect = 1e-16
Identities = 54/188 (28%), Positives = 91/188 (48%), Gaps = 1/188 (0%)
Frame = +2
Query: 62 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADL 241
+AGKVV GA++ + ++ + + ++ + I D+
Sbjct: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQE---LPGAVFILCDV 63
Query: 242 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNVRSIYYLTM 418
T+E D++ ++ +TI +G+LD +VNNAG E TS + +L+ N+ Y LT
Sbjct: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123
Query: 419 LAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVN 598
LA+P+L +S+G G + Y +K +V T+ +AL +P GVRVNC++
Sbjct: 124 LALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCIS 183
Query: 599 PXVILTEL 622
P I T L
Sbjct: 184 PGNIWTPL 191
>AY358430-1|AAQ88796.1| 270|Homo sapiens ATGT502 protein.
Length = 270
Score = 85.4 bits (202), Expect = 1e-16
Identities = 54/188 (28%), Positives = 91/188 (48%), Gaps = 1/188 (0%)
Frame = +2
Query: 62 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADL 241
+AGKVV GA++ + ++ + + ++ + I D+
Sbjct: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQE---LPGAVFILCDV 63
Query: 242 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNVRSIYYLTM 418
T+E D++ ++ +TI +G+LD +VNNAG E TS + +L+ N+ Y LT
Sbjct: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123
Query: 419 LAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVN 598
LA+P+L +S+G G + Y +K +V T+ +AL +P GVRVNC++
Sbjct: 124 LALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCIS 183
Query: 599 PXVILTEL 622
P I T L
Sbjct: 184 PGNIWTPL 191
>AF126781-1|AAF06940.1| 270|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR3 protein.
Length = 270
Score = 85.4 bits (202), Expect = 1e-16
Identities = 54/188 (28%), Positives = 91/188 (48%), Gaps = 1/188 (0%)
Frame = +2
Query: 62 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADL 241
+AGKVV GA++ + ++ + + ++ + I D+
Sbjct: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQE---LPGAVFILCDV 63
Query: 242 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNVRSIYYLTM 418
T+E D++ ++ +TI +G+LD +VNNAG E TS + +L+ N+ Y LT
Sbjct: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123
Query: 419 LAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVN 598
LA+P+L +S+G G + Y +K +V T+ +AL +P GVRVNC++
Sbjct: 124 LALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCIS 183
Query: 599 PXVILTEL 622
P I T L
Sbjct: 184 PGNIWTPL 191
>U31875-1|AAA82048.1| 280|Homo sapiens Hep27 protein protein.
Length = 280
Score = 84.6 bits (200), Expect = 3e-16
Identities = 49/166 (29%), Positives = 88/166 (53%), Gaps = 2/166 (1%)
Frame = +2
Query: 128 LSKLGAQLSLTGRNVENLQK-VSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 304
L++ GA + ++ R +N+ + ++K + S I + K D E+++ K ++H G +D
Sbjct: 56 LARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEHCGGVD 115
Query: 305 VLVNNAGIIE-TGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 481
LV +AG+ G+ TS +D++++ NV+S L +P++ +G
Sbjct: 116 FLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLLSQLLPYMENRRGAVILVSSIAA 175
Query: 482 IRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTE 619
+ YN+SK ++ TR +AL LAPK +RVNCV P +I T+
Sbjct: 176 YNPVVALGVYNVSKTALLGLTRTLALELAPKDIRVNCVVPGIIKTD 221
>BC007339-1|AAH07339.2| 271|Homo sapiens DHRS2 protein protein.
Length = 271
Score = 84.6 bits (200), Expect = 3e-16
Identities = 49/166 (29%), Positives = 88/166 (53%), Gaps = 2/166 (1%)
Frame = +2
Query: 128 LSKLGAQLSLTGRNVENLQK-VSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 304
L++ GA + ++ R +N+ + ++K + S I + K D E+++ K ++H G +D
Sbjct: 47 LARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEHCGGVD 106
Query: 305 VLVNNAGIIE-TGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 481
LV +AG+ G+ TS +D++++ NV+S L +P++ +G
Sbjct: 107 FLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLLSQLLPYMENRRGAVILVSSIAA 166
Query: 482 IRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTE 619
+ YN+SK ++ TR +AL LAPK +RVNCV P +I T+
Sbjct: 167 YNPVVALGVYNVSKTALLGLTRTLALELAPKDIRVNCVVPGIIKTD 212
>BC002786-1|AAH02786.1| 300|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 protein.
Length = 300
Score = 84.6 bits (200), Expect = 3e-16
Identities = 49/166 (29%), Positives = 88/166 (53%), Gaps = 2/166 (1%)
Frame = +2
Query: 128 LSKLGAQLSLTGRNVENLQK-VSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 304
L++ GA + ++ R +N+ + ++K + S I + K D E+++ K ++H G +D
Sbjct: 56 LARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEHCGGVD 115
Query: 305 VLVNNAGIIE-TGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 481
LV +AG+ G+ TS +D++++ NV+S L +P++ +G
Sbjct: 116 FLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLLSQLLPYMENRRGAVILVSSIAA 175
Query: 482 IRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTE 619
+ YN+SK ++ TR +AL LAPK +RVNCV P +I T+
Sbjct: 176 YNPVVALGVYNVSKTALLGLTRTLALELAPKDIRVNCVVPGIIKTD 221
>AF244132-1|AAG33703.1| 280|Homo sapiens short-chain alcohol
dehydrogenase protein.
Length = 280
Score = 84.6 bits (200), Expect = 3e-16
Identities = 49/166 (29%), Positives = 88/166 (53%), Gaps = 2/166 (1%)
Frame = +2
Query: 128 LSKLGAQLSLTGRNVENLQK-VSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 304
L++ GA + ++ R +N+ + ++K + S I + K D E+++ K ++H G +D
Sbjct: 56 LARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEHCGGVD 115
Query: 305 VLVNNAGIIE-TGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 481
LV +AG+ G+ TS +D++++ NV+S L +P++ +G
Sbjct: 116 FLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLLSQLLPYMENRRGAVILVSSIAA 175
Query: 482 IRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTE 619
+ YN+SK ++ TR +AL LAPK +RVNCV P +I T+
Sbjct: 176 YNPVVALGVYNVSKTALLGLTRTLALELAPKDIRVNCVVPGIIKTD 221
>AK222857-1|BAD96577.1| 280|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 isoform 2 variant protein.
Length = 280
Score = 81.8 bits (193), Expect = 2e-15
Identities = 48/166 (28%), Positives = 88/166 (53%), Gaps = 2/166 (1%)
Frame = +2
Query: 128 LSKLGAQLSLTGRNVENLQK-VSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 304
L++ GA + ++ R +N+ + ++K + S I + K D E+++ K ++H G +D
Sbjct: 56 LARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEHCGGVD 115
Query: 305 VLVNNAGIIE-TGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 481
LV +AG+ G+ TS +D++++ NV+S L +P++ +G
Sbjct: 116 FLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPAPLLSQLLPYMENRRGAVILVSSVAA 175
Query: 482 IRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTE 619
+ Y++SK ++ TR +AL LAPK +RVNCV P +I T+
Sbjct: 176 YNPVVALGVYSVSKTALLGLTRTLALELAPKDIRVNCVVPGIIKTD 221
>BC007337-1|AAH07337.1| 339|Homo sapiens dehydrogenase/reductase
(SDR family) member 7 protein.
Length = 339
Score = 74.9 bits (176), Expect = 2e-13
Identities = 52/172 (30%), Positives = 80/172 (46%), Gaps = 7/172 (4%)
Frame = +2
Query: 128 LSKLGAQLSLTGRNVENLQKVSKDCD-----KFASTLSITADLTKESDIEKIIKKTIDHY 292
LSKLG L L+ R V L++V + C K L + DLT E K + +
Sbjct: 70 LSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEF 129
Query: 293 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXX 469
G++D+LVNN G+ + +TSL Y +L+ N LT +PH++E K G
Sbjct: 130 GRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVN 189
Query: 470 XXXGIRSFPGVLAYNISKASVDQFTRCVALXLAP-KGVRVNCVNPXVILTEL 622
GI S P + Y SK ++ F + LA G+ V+ + P + + +
Sbjct: 190 SILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGIIVSNICPGPVQSNI 241
>BC000637-1|AAH00637.1| 339|Homo sapiens dehydrogenase/reductase
(SDR family) member 7 protein.
Length = 339
Score = 74.9 bits (176), Expect = 2e-13
Identities = 52/172 (30%), Positives = 80/172 (46%), Gaps = 7/172 (4%)
Frame = +2
Query: 128 LSKLGAQLSLTGRNVENLQKVSKDCD-----KFASTLSITADLTKESDIEKIIKKTIDHY 292
LSKLG L L+ R V L++V + C K L + DLT E K + +
Sbjct: 70 LSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEF 129
Query: 293 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXX 469
G++D+LVNN G+ + +TSL Y +L+ N LT +PH++E K G
Sbjct: 130 GRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVN 189
Query: 470 XXXGIRSFPGVLAYNISKASVDQFTRCVALXLAP-KGVRVNCVNPXVILTEL 622
GI S P + Y SK ++ F + LA G+ V+ + P + + +
Sbjct: 190 SILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGIIVSNICPGPVQSNI 241
>AY359031-1|AAQ89390.1| 289|Homo sapiens oxidoreductase/S-2 H
protein.
Length = 289
Score = 74.9 bits (176), Expect = 2e-13
Identities = 52/172 (30%), Positives = 80/172 (46%), Gaps = 7/172 (4%)
Frame = +2
Query: 128 LSKLGAQLSLTGRNVENLQKVSKDCD-----KFASTLSITADLTKESDIEKIIKKTIDHY 292
LSKLG L L+ R V L++V + C K L + DLT E K + +
Sbjct: 20 LSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEF 79
Query: 293 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXX 469
G++D+LVNN G+ + +TSL Y +L+ N LT +PH++E K G
Sbjct: 80 GRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVN 139
Query: 470 XXXGIRSFPGVLAYNISKASVDQFTRCVALXLAP-KGVRVNCVNPXVILTEL 622
GI S P + Y SK ++ F + LA G+ V+ + P + + +
Sbjct: 140 SILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGIIVSNICPGPVQSNI 191
>AF151844-1|AAD34081.1| 339|Homo sapiens CGI-86 protein protein.
Length = 339
Score = 74.9 bits (176), Expect = 2e-13
Identities = 52/172 (30%), Positives = 80/172 (46%), Gaps = 7/172 (4%)
Frame = +2
Query: 128 LSKLGAQLSLTGRNVENLQKVSKDCD-----KFASTLSITADLTKESDIEKIIKKTIDHY 292
LSKLG L L+ R V L++V + C K L + DLT E K + +
Sbjct: 70 LSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEF 129
Query: 293 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXX 469
G++D+LVNN G+ + +TSL Y +L+ N LT +PH++E K G
Sbjct: 130 GRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVN 189
Query: 470 XXXGIRSFPGVLAYNISKASVDQFTRCVALXLAP-KGVRVNCVNPXVILTEL 622
GI S P + Y SK ++ F + LA G+ V+ + P + + +
Sbjct: 190 SILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGIIVSNICPGPVQSNI 241
>AF126782-1|AAF06941.1| 289|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR4 protein.
Length = 289
Score = 74.9 bits (176), Expect = 2e-13
Identities = 52/172 (30%), Positives = 80/172 (46%), Gaps = 7/172 (4%)
Frame = +2
Query: 128 LSKLGAQLSLTGRNVENLQKVSKDCD-----KFASTLSITADLTKESDIEKIIKKTIDHY 292
LSKLG L L+ R V L++V + C K L + DLT E K + +
Sbjct: 20 LSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEF 79
Query: 293 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXX 469
G++D+LVNN G+ + +TSL Y +L+ N LT +PH++E K G
Sbjct: 80 GRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVN 139
Query: 470 XXXGIRSFPGVLAYNISKASVDQFTRCVALXLAP-KGVRVNCVNPXVILTEL 622
GI S P + Y SK ++ F + LA G+ V+ + P + + +
Sbjct: 140 SILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGIIVSNICPGPVQSNI 191
>AK001870-1|BAA91953.1| 278|Homo sapiens protein ( Homo sapiens
cDNA FLJ11008 fis, clone PLACE1003100, moderately
similar to HEP27 PROTEIN. ).
Length = 278
Score = 73.7 bits (173), Expect = 5e-13
Identities = 48/187 (25%), Positives = 89/187 (47%), Gaps = 3/187 (1%)
Frame = +2
Query: 65 AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENL-QKVSKDCDKFASTLSITADL 241
A KV L++ GA + ++ R +N+ Q V+ + S +
Sbjct: 31 ANKVALATASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHV 90
Query: 242 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTM 418
K D E+++ + +G +D+LV+NA + G+I + + +D+ ++ NV++ +T
Sbjct: 91 GKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTK 150
Query: 419 LAVPHLLESKGXXXXXXXXXGIRS-FPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCV 595
VP + + G S PG YN+SK ++ T+ +A+ LAP+ +RVNC+
Sbjct: 151 AVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCL 210
Query: 596 NPXVILT 616
P +I T
Sbjct: 211 APGLIKT 217
>DQ344810-1|ABD75823.1| 278|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase short isoform protein.
Length = 278
Score = 73.3 bits (172), Expect = 6e-13
Identities = 48/187 (25%), Positives = 89/187 (47%), Gaps = 3/187 (1%)
Frame = +2
Query: 65 AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENL-QKVSKDCDKFASTLSITADL 241
A KV L++ GA + ++ R +N+ Q V+ + S +
Sbjct: 31 ANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHV 90
Query: 242 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTM 418
K D E+++ + +G +D+LV+NA + G+I + + +D+ ++ NV++ +T
Sbjct: 91 GKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTK 150
Query: 419 LAVPHLLESKGXXXXXXXXXGIRS-FPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCV 595
VP + + G S PG YN+SK ++ T+ +A+ LAP+ +RVNC+
Sbjct: 151 AVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCL 210
Query: 596 NPXVILT 616
P +I T
Sbjct: 211 APGLIKT 217
>BC003019-1|AAH03019.1| 278|Homo sapiens dehydrogenase/reductase
(SDR family) member 4 protein.
Length = 278
Score = 73.3 bits (172), Expect = 6e-13
Identities = 48/187 (25%), Positives = 89/187 (47%), Gaps = 3/187 (1%)
Frame = +2
Query: 65 AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENL-QKVSKDCDKFASTLSITADL 241
A KV L++ GA + ++ R +N+ Q V+ + S +
Sbjct: 31 ANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHV 90
Query: 242 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTM 418
K D E+++ + +G +D+LV+NA + G+I + + +D+ ++ NV++ +T
Sbjct: 91 GKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTK 150
Query: 419 LAVPHLLESKGXXXXXXXXXGIRS-FPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCV 595
VP + + G S PG YN+SK ++ T+ +A+ LAP+ +RVNC+
Sbjct: 151 AVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCL 210
Query: 596 NPXVILT 616
P +I T
Sbjct: 211 APGLIKT 217
>BC002529-1|AAH02529.1| 303|Homo sapiens peroxisomal
trans-2-enoyl-CoA reductase protein.
Length = 303
Score = 73.3 bits (172), Expect = 6e-13
Identities = 42/170 (24%), Positives = 79/170 (46%), Gaps = 6/170 (3%)
Frame = +2
Query: 128 LSKLGAQLSLTGRNVENLQKVSKDCD------KFASTLSITADLTKESDIEKIIKKTIDH 289
L +LG+ + + R +E L+ + + K A + I ++ E ++ ++K T+D
Sbjct: 38 LLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDT 97
Query: 290 YGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXX 469
+GK++ LVNN G E+ S + ++ TN+ +Y+ ++ G
Sbjct: 98 FGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNI 157
Query: 470 XXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTE 619
FP + ++A V T+ +AL A G+R+NCV P VI ++
Sbjct: 158 IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQ 207
>AY358638-1|AAQ89001.1| 278|Homo sapiens SCAD-SRL protein.
Length = 278
Score = 73.3 bits (172), Expect = 6e-13
Identities = 48/187 (25%), Positives = 89/187 (47%), Gaps = 3/187 (1%)
Frame = +2
Query: 65 AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENL-QKVSKDCDKFASTLSITADL 241
A KV L++ GA + ++ R +N+ Q V+ + S +
Sbjct: 31 ANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHV 90
Query: 242 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTM 418
K D E+++ + +G +D+LV+NA + G+I + + +D+ ++ NV++ +T
Sbjct: 91 GKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTK 150
Query: 419 LAVPHLLESKGXXXXXXXXXGIRS-FPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCV 595
VP + + G S PG YN+SK ++ T+ +A+ LAP+ +RVNC+
Sbjct: 151 AVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCL 210
Query: 596 NPXVILT 616
P +I T
Sbjct: 211 APGLIKT 217
>AF232009-1|AAF69798.1| 303|Homo sapiens peroxisomal trans 2-enoyl
CoA reductase protein.
Length = 303
Score = 73.3 bits (172), Expect = 6e-13
Identities = 42/170 (24%), Positives = 79/170 (46%), Gaps = 6/170 (3%)
Frame = +2
Query: 128 LSKLGAQLSLTGRNVENLQKVSKDCD------KFASTLSITADLTKESDIEKIIKKTIDH 289
L +LG+ + + R +E L+ + + K A + I ++ E ++ ++K T+D
Sbjct: 38 LLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDT 97
Query: 290 YGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXX 469
+GK++ LVNN G E+ S + ++ TN+ +Y+ ++ G
Sbjct: 98 FGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNI 157
Query: 470 XXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTE 619
FP + ++A V T+ +AL A G+R+NCV P VI ++
Sbjct: 158 IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQ 207
>AF212234-1|AAK14920.1| 322|Homo sapiens HPDHase protein.
Length = 322
Score = 73.3 bits (172), Expect = 6e-13
Identities = 42/170 (24%), Positives = 79/170 (46%), Gaps = 6/170 (3%)
Frame = +2
Query: 128 LSKLGAQLSLTGRNVENLQKVSKDCD------KFASTLSITADLTKESDIEKIIKKTIDH 289
L +LG+ + + R +E L+ + + K A + I ++ E ++ ++K T+D
Sbjct: 57 LLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDT 116
Query: 290 YGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXX 469
+GK++ LVNN G E+ S + ++ TN+ +Y+ ++ G
Sbjct: 117 FGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNI 176
Query: 470 XXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTE 619
FP + ++A V T+ +AL A G+R+NCV P VI ++
Sbjct: 177 IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQ 226
>AC010686-2|AAY14657.1| 303|Homo sapiens unknown protein.
Length = 303
Score = 73.3 bits (172), Expect = 6e-13
Identities = 42/170 (24%), Positives = 79/170 (46%), Gaps = 6/170 (3%)
Frame = +2
Query: 128 LSKLGAQLSLTGRNVENLQKVSKDCD------KFASTLSITADLTKESDIEKIIKKTIDH 289
L +LG+ + + R +E L+ + + K A + I ++ E ++ ++K T+D
Sbjct: 38 LLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDT 97
Query: 290 YGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXX 469
+GK++ LVNN G E+ S + ++ TN+ +Y+ ++ G
Sbjct: 98 FGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNI 157
Query: 470 XXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTE 619
FP + ++A V T+ +AL A G+R+NCV P VI ++
Sbjct: 158 IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQ 207
>AB045131-1|BAB18775.1| 260|Homo sapiens NADPH-dependent retinol
dehydrogenase/reductase protein.
Length = 260
Score = 73.3 bits (172), Expect = 6e-13
Identities = 48/187 (25%), Positives = 89/187 (47%), Gaps = 3/187 (1%)
Frame = +2
Query: 65 AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENL-QKVSKDCDKFASTLSITADL 241
A KV L++ GA + ++ R +N+ Q V+ + S +
Sbjct: 13 ANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHV 72
Query: 242 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTM 418
K D E+++ + +G +D+LV+NA + G+I + + +D+ ++ NV++ +T
Sbjct: 73 GKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTK 132
Query: 419 LAVPHLLESKGXXXXXXXXXGIRS-FPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCV 595
VP + + G S PG YN+SK ++ T+ +A+ LAP+ +RVNC+
Sbjct: 133 AVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCL 192
Query: 596 NPXVILT 616
P +I T
Sbjct: 193 APGLIKT 199
>AJ250303-1|CAB89810.1| 303|Homo sapiens peroxisomal 2-enoyl-CoA
reductase protein.
Length = 303
Score = 72.9 bits (171), Expect = 8e-13
Identities = 42/170 (24%), Positives = 79/170 (46%), Gaps = 6/170 (3%)
Frame = +2
Query: 128 LSKLGAQLSLTGRNVENLQKVSKDCD------KFASTLSITADLTKESDIEKIIKKTIDH 289
L +LG+ + + R +E L+ + + K A + I ++ E ++ ++K T+D
Sbjct: 38 LLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDT 97
Query: 290 YGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXX 469
+GK++ LVNN G E+ S + ++ TN+ +Y+ ++ G
Sbjct: 98 FGKINFLVNNGGGQFLSPAEHISSKGWHAVLRTNLTGSFYMCKAVYSSWMKEHGGSIVNI 157
Query: 470 XXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTE 619
FP + ++A V T+ +AL A G+R+NCV P VI ++
Sbjct: 158 IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQ 207
>AF064256-1|AAQ13444.1| 278|Homo sapiens Hep27-like protein
protein.
Length = 278
Score = 72.5 bits (170), Expect = 1e-12
Identities = 48/187 (25%), Positives = 89/187 (47%), Gaps = 3/187 (1%)
Frame = +2
Query: 65 AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENL-QKVSKDCDKFASTLSITADL 241
A KV L++ GA + ++ R +N+ Q V+ + S +
Sbjct: 31 ANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCMV 90
Query: 242 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTM 418
K D E+++ + +G +D+LV+NA + G+I + + +D+ ++ NV++ +T
Sbjct: 91 GKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTK 150
Query: 419 LAVPHLLESKGXXXXXXXXXGIRS-FPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCV 595
VP + + G S PG YN+SK ++ T+ +A+ LAP+ +RVNC+
Sbjct: 151 AVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCL 210
Query: 596 NPXVILT 616
P +I T
Sbjct: 211 APGLIKT 217
>AF044127-1|AAD02292.1| 260|Homo sapiens peroxisomal short-chain
alcohol dehydrogenase protein.
Length = 260
Score = 72.5 bits (170), Expect = 1e-12
Identities = 47/187 (25%), Positives = 89/187 (47%), Gaps = 3/187 (1%)
Frame = +2
Query: 65 AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENL-QKVSKDCDKFASTLSITADL 241
A KV L++ GA + ++ R +N+ Q V+ + S +
Sbjct: 13 ANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHV 72
Query: 242 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTM 418
K D E+++ + +G +D+LV+NA + G++ + + +D+ ++ NV++ +T
Sbjct: 73 GKAEDRERLVAMAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVKAPALMTK 132
Query: 419 LAVPHLLESKGXXXXXXXXXGIRS-FPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCV 595
VP + + G S PG YN+SK ++ T+ +A+ LAP+ +RVNC+
Sbjct: 133 AVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCL 192
Query: 596 NPXVILT 616
P +I T
Sbjct: 193 APGLIKT 199
>BC095414-1|AAH95414.1| 245|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 2 protein.
Length = 245
Score = 70.5 bits (165), Expect = 4e-12
Identities = 48/185 (25%), Positives = 81/185 (43%), Gaps = 2/185 (1%)
Frame = +2
Query: 68 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTK 247
GKV+ ++ GA++ T N LQ++ +K+ + D+TK
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL----EKYPGIQTRVLDVTK 61
Query: 248 ESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAV 427
+ I++ + +LDVL N AG + GT+ + +D MN NVRS+Y + +
Sbjct: 62 KKQIDQFANEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFL 117
Query: 428 PHLLESK--GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNP 601
P +L K ++ Y+ +KA+V T+ VA +G+R NCV P
Sbjct: 118 PKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCP 177
Query: 602 XVILT 616
+ T
Sbjct: 178 GTVDT 182
>BC001953-1|AAH01953.1| 245|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 2 protein.
Length = 245
Score = 70.5 bits (165), Expect = 4e-12
Identities = 48/185 (25%), Positives = 81/185 (43%), Gaps = 2/185 (1%)
Frame = +2
Query: 68 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTK 247
GKV+ ++ GA++ T N LQ++ +K+ + D+TK
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL----EKYPGIQTRVLDVTK 61
Query: 248 ESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAV 427
+ I++ + +LDVL N AG + GT+ + +D MN NVRS+Y + +
Sbjct: 62 KKQIDQFASEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFL 117
Query: 428 PHLLESK--GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNP 601
P +L K ++ Y+ +KA+V T+ VA +G+R NCV P
Sbjct: 118 PKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCP 177
Query: 602 XVILT 616
+ T
Sbjct: 178 GTVDT 182
>AF164790-1|AAF80754.1| 245|Homo sapiens oxidoreductase UCPA
protein.
Length = 245
Score = 70.5 bits (165), Expect = 4e-12
Identities = 48/185 (25%), Positives = 81/185 (43%), Gaps = 2/185 (1%)
Frame = +2
Query: 68 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTK 247
GKV+ ++ GA++ T N LQ++ +K+ + D+TK
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL----EKYPGIQTRVLDVTK 61
Query: 248 ESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAV 427
+ I++ + +LDVL N AG + GT+ + +D MN NVRS+Y + +
Sbjct: 62 KKQIDQFANEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFL 117
Query: 428 PHLLESK--GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNP 601
P +L K ++ Y+ +KA+V T+ VA +G+R NCV P
Sbjct: 118 PKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCP 177
Query: 602 XVILT 616
+ T
Sbjct: 178 GTVDT 182
>AY358841-1|AAQ89200.1| 245|Homo sapiens GRLD6308 protein.
Length = 245
Score = 69.3 bits (162), Expect = 1e-11
Identities = 47/185 (25%), Positives = 81/185 (43%), Gaps = 2/185 (1%)
Frame = +2
Query: 68 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTK 247
GKV+ ++ GA++ T N LQ++ +K+ + D+TK
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL----EKYPGIQTRVLDVTK 61
Query: 248 ESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAV 427
+ I++ + +LDVL N AG + GT+ + +D MN NVRS+Y + +
Sbjct: 62 KKQIDQFASEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFL 117
Query: 428 PHLLESK--GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNP 601
P +L K ++ Y+ +KA+V T+ +A +G+R NCV P
Sbjct: 118 PKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSLAADFIQQGIRCNCVCP 177
Query: 602 XVILT 616
+ T
Sbjct: 178 GTVDT 182
>BC033650-1|AAH33650.1| 237|Homo sapiens carbonyl reductase 4
protein.
Length = 237
Score = 68.1 bits (159), Expect = 2e-11
Identities = 41/166 (24%), Positives = 80/166 (48%), Gaps = 1/166 (0%)
Frame = +2
Query: 128 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 307
+++ G +L++ RN+E + + D L+ + D+ KE D++ ++ H G+++
Sbjct: 22 MARKGYRLAVIARNLEGAKAAAGDLG--GDHLAFSCDVAKEHDVQNTFEELEKHLGRVNF 79
Query: 308 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 484
LVN AGI G + T ++TN+ A+ +++ + G G+
Sbjct: 80 LVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQGGSIVNVGSIVGL 139
Query: 485 RSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTEL 622
+ G Y+ SK + F+R +A +A K +RVN V P + T++
Sbjct: 140 KGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHTDM 185
>BC021973-1|AAH21973.1| 237|Homo sapiens carbonyl reductase 4
protein.
Length = 237
Score = 68.1 bits (159), Expect = 2e-11
Identities = 41/166 (24%), Positives = 80/166 (48%), Gaps = 1/166 (0%)
Frame = +2
Query: 128 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 307
+++ G +L++ RN+E + + D L+ + D+ KE D++ ++ H G+++
Sbjct: 22 MARKGYRLAVIARNLEGAKAAAGDLG--GDHLAFSCDVAKEHDVQNTFEEMEKHLGRVNF 79
Query: 308 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 484
LVN AGI G + T ++TN+ A+ +++ + G G+
Sbjct: 80 LVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQGGSIVNVGSIVGL 139
Query: 485 RSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTEL 622
+ G Y+ SK + F+R +A +A K +RVN V P + T++
Sbjct: 140 KGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHTDM 185
>CR457124-1|CAG33405.1| 325|Homo sapiens DKFZp566O084 protein.
Length = 325
Score = 65.7 bits (153), Expect = 1e-10
Identities = 49/169 (28%), Positives = 77/169 (45%), Gaps = 8/169 (4%)
Frame = +2
Query: 140 GAQLSLTGRNVENLQKVSKDCDKFAST-------LSITADLTKESDIEKIIKKTIDHYGK 298
GA+L L GRN L+++ ++ +T +T DLT I + + +G
Sbjct: 76 GAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVTFDLTDSGAIVAAAAEILQCFGY 135
Query: 299 LDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXX 475
+D+LVNNAGI GTI +T++ R+M TN LT +P +++ + G
Sbjct: 136 VDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQGHIVAISSI 195
Query: 476 XGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTEL 622
G S P AY SK + F C+ + + V ++P I T L
Sbjct: 196 QGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNL 244
>BC009679-1|AAH09679.1| 325|Homo sapiens dehydrogenase/reductase
(SDR family) member 7B protein.
Length = 325
Score = 65.7 bits (153), Expect = 1e-10
Identities = 49/169 (28%), Positives = 77/169 (45%), Gaps = 8/169 (4%)
Frame = +2
Query: 140 GAQLSLTGRNVENLQKVSKDCDKFAST-------LSITADLTKESDIEKIIKKTIDHYGK 298
GA+L L GRN L+++ ++ +T +T DLT I + + +G
Sbjct: 76 GAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVTFDLTDSGAIVAAAAEILQCFGY 135
Query: 299 LDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXX 475
+D+LVNNAGI GTI +T++ R+M TN LT +P +++ + G
Sbjct: 136 VDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQGHIVAISSI 195
Query: 476 XGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTEL 622
G S P AY SK + F C+ + + V ++P I T L
Sbjct: 196 QGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNL 244
>BC004126-1|AAH04126.1| 325|Homo sapiens dehydrogenase/reductase
(SDR family) member 7B protein.
Length = 325
Score = 65.7 bits (153), Expect = 1e-10
Identities = 49/169 (28%), Positives = 77/169 (45%), Gaps = 8/169 (4%)
Frame = +2
Query: 140 GAQLSLTGRNVENLQKVSKDCDKFAST-------LSITADLTKESDIEKIIKKTIDHYGK 298
GA+L L GRN L+++ ++ +T +T DLT I + + +G
Sbjct: 76 GAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVTFDLTDSGAIVAAAAEILQCFGY 135
Query: 299 LDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXX 475
+D+LVNNAGI GTI +T++ R+M TN LT +P +++ + G
Sbjct: 136 VDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQGHIVAISSI 195
Query: 476 XGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTEL 622
G S P AY SK + F C+ + + V ++P I T L
Sbjct: 196 QGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNL 244
>AY358498-1|AAQ88862.1| 310|Homo sapiens DFIT212 protein.
Length = 310
Score = 65.7 bits (153), Expect = 1e-10
Identities = 49/169 (28%), Positives = 77/169 (45%), Gaps = 8/169 (4%)
Frame = +2
Query: 140 GAQLSLTGRNVENLQKVSKDCDKFAST-------LSITADLTKESDIEKIIKKTIDHYGK 298
GA+L L GRN L+++ ++ +T +T DLT I + + +G
Sbjct: 61 GAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVTFDLTDSGAIVAAAAEILQCFGY 120
Query: 299 LDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXX 475
+D+LVNNAGI GTI +T++ R+M TN LT +P +++ + G
Sbjct: 121 VDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQGHIVAISSI 180
Query: 476 XGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTEL 622
G S P AY SK + F C+ + + V ++P I T L
Sbjct: 181 QGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNL 229
>AF151851-1|AAD34088.1| 291|Homo sapiens CGI-93 protein protein.
Length = 291
Score = 65.7 bits (153), Expect = 1e-10
Identities = 49/169 (28%), Positives = 77/169 (45%), Gaps = 8/169 (4%)
Frame = +2
Query: 140 GAQLSLTGRNVENLQKVSKDCDKFAST-------LSITADLTKESDIEKIIKKTIDHYGK 298
GA+L L GRN L+++ ++ +T +T DLT I + + +G
Sbjct: 81 GAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVTFDLTDSGAIVAAAAEILQCFGY 140
Query: 299 LDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXX 475
+D+LVNNAGI GTI +T++ R+M TN LT +P +++ + G
Sbjct: 141 VDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQGHIVAISSI 200
Query: 476 XGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTEL 622
G S P AY SK + F C+ + + V ++P I T L
Sbjct: 201 QGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNL 249
>AK027337-1|BAB55045.1| 179|Homo sapiens protein ( Homo sapiens
cDNA FLJ14431 fis, clone HEMBA1006521, weakly similar to
3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE (EC
1.1.1.100). ).
Length = 179
Score = 65.3 bits (152), Expect = 2e-10
Identities = 40/159 (25%), Positives = 76/159 (47%), Gaps = 1/159 (0%)
Frame = +2
Query: 128 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 307
+++ G +L++ RN+E + + D L+ + D+ KE D++ ++ H G+++
Sbjct: 22 MARKGYRLAVIARNLEGAKAAAGDLG--GDHLAFSCDVAKEHDVQNTFEEMEKHLGRVNF 79
Query: 308 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 484
LVN AGI G + T ++TN+ A+ +++ + G G+
Sbjct: 80 LVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQGGSIVNVGSIVGL 139
Query: 485 RSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNP 601
+ G Y+ SK + F+R +A +A K +RVN V P
Sbjct: 140 KGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAP 178
>BC000663-1|AAH00663.2| 230|Homo sapiens dehydrogenase/reductase
(SDR family) member 4 like 2 protein.
Length = 230
Score = 61.7 bits (143), Expect = 2e-09
Identities = 38/155 (24%), Positives = 77/155 (49%), Gaps = 3/155 (1%)
Frame = +2
Query: 143 AQLSLTGRNVENL-QKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 319
A + ++ R +N+ Q V+ + S + K D E+++ + +G +D+LV+N
Sbjct: 55 AHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERLVAMAVKLHGGIDILVSN 114
Query: 320 AGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRS-F 493
A + G++ + + +D+ ++ NV++ +T VP + + G S
Sbjct: 115 AAVNPFFGSLMDVTEEVWDKTLDINVKAPALMTKAVVPEMEKRGGGSVVIVSSIAAFSPS 174
Query: 494 PGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVN 598
PG YN+SK ++ +A+ LAP+ +RVNC++
Sbjct: 175 PGFSPYNVSKTALLGLNNTLAIELAPRNIRVNCLH 209
>X63657-1|CAA45197.1| 332|Homo sapiens FVT1 protein.
Length = 332
Score = 60.1 bits (139), Expect = 6e-09
Identities = 39/163 (23%), Positives = 77/163 (47%), Gaps = 7/163 (4%)
Frame = +2
Query: 134 KLGAQLSLTGRNVENLQKVSKDCDKFAST-----LSITADLTKE-SDIEKIIKKTIDHYG 295
K GA ++L RN + L + K+ + + L I+ D++++ + +E +IK+ + G
Sbjct: 54 KQGAFITLVARNEDKLLQAKKEIEMHSINDKQVVLCISVDVSQDYNQVENVIKQAQEKLG 113
Query: 296 KLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXX 472
+D+LVN AG+ +G E+ ++ ++RLM+ N Y + + + E + G
Sbjct: 114 PVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVGRIVFVSS 173
Query: 473 XXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNP 601
G G AY+ SK ++ + + + P V + P
Sbjct: 174 QAGQLGLFGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYP 216
>BT006782-1|AAP35428.1| 332|Homo sapiens follicular lymphoma
variant translocation 1 protein.
Length = 332
Score = 60.1 bits (139), Expect = 6e-09
Identities = 39/163 (23%), Positives = 77/163 (47%), Gaps = 7/163 (4%)
Frame = +2
Query: 134 KLGAQLSLTGRNVENLQKVSKDCDKFAST-----LSITADLTKE-SDIEKIIKKTIDHYG 295
K GA ++L RN + L + K+ + + L I+ D++++ + +E +IK+ + G
Sbjct: 54 KQGAFITLVARNEDKLLQAKKEIEMHSINDKQVVLCISVDVSQDYNQVENVIKQAQEKLG 113
Query: 296 KLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXX 472
+D+LVN AG+ +G E+ ++ ++RLM+ N Y + + + E + G
Sbjct: 114 PVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVGRIVFVSS 173
Query: 473 XXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNP 601
G G AY+ SK ++ + + + P V + P
Sbjct: 174 QAGQLGLFGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYP 216
>BC008797-1|AAH08797.1| 332|Homo sapiens follicular lymphoma
variant translocation 1 protein.
Length = 332
Score = 60.1 bits (139), Expect = 6e-09
Identities = 39/163 (23%), Positives = 77/163 (47%), Gaps = 7/163 (4%)
Frame = +2
Query: 134 KLGAQLSLTGRNVENLQKVSKDCDKFAST-----LSITADLTKE-SDIEKIIKKTIDHYG 295
K GA ++L RN + L + K+ + + L I+ D++++ + +E +IK+ + G
Sbjct: 54 KQGAFITLVARNEDKLLQAKKEIEMHSINDKQVVLCISVDVSQDYNQVENVIKQAQEKLG 113
Query: 296 KLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXX 472
+D+LVN AG+ +G E+ ++ ++RLM+ N Y + + + E + G
Sbjct: 114 PVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVGRIVFVSS 173
Query: 473 XXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNP 601
G G AY+ SK ++ + + + P V + P
Sbjct: 174 QAGQLGLFGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYP 216
>BC104218-1|AAI04219.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 59.7 bits (138), Expect = 8e-09
Identities = 47/171 (27%), Positives = 81/171 (47%), Gaps = 6/171 (3%)
Frame = +2
Query: 128 LSKLGAQLSLTGRNVENLQKVSKD-CDKF-ASTLSITADLTKESDIEKIIKKTIDHYGKL 301
L+ G + L RN E LQ V+KD D + T I AD + +I I++ + +
Sbjct: 87 LASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADFSSGREIYLPIREALKDKD-V 145
Query: 302 DVLVNNAGIIETGTIENTSLAQYDRL---MNTNVRSIYYLTMLAVPHLLE-SKGXXXXXX 469
+LVNN G+ T L++ D+L +N N+ + + + +P ++E KG
Sbjct: 146 GILVNNVGVFYPYPQYFTQLSE-DKLWDIINVNIAAASLMVHVVLPGMVERKKGAIVTIS 204
Query: 470 XXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTEL 622
+ P + A++ SKA +D F+R + A KG+ V + P + T +
Sbjct: 205 SGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVATSM 255
>AY028377-1|AAK16927.1| 309|Homo sapiens steroid dehydrogenase-like
protein protein.
Length = 309
Score = 59.7 bits (138), Expect = 8e-09
Identities = 47/171 (27%), Positives = 81/171 (47%), Gaps = 6/171 (3%)
Frame = +2
Query: 128 LSKLGAQLSLTGRNVENLQKVSKD-CDKF-ASTLSITADLTKESDIEKIIKKTIDHYGKL 301
L+ G + L RN E LQ V+KD D + T I AD + +I I++ + +
Sbjct: 66 LASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADFSSGREIYLPIREALKDKD-V 124
Query: 302 DVLVNNAGIIETGTIENTSLAQYDRL---MNTNVRSIYYLTMLAVPHLLE-SKGXXXXXX 469
+LVNN G+ T L++ D+L +N N+ + + + +P ++E KG
Sbjct: 125 GILVNNVGVFYPYPQYFTQLSE-DKLWDIINVNIAAASLMVHVVLPGMVERKKGAIVTIS 183
Query: 470 XXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTEL 622
+ P + A++ SKA +D F+R + A KG+ V + P + T +
Sbjct: 184 SGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVATSM 234
>AK074878-1|BAC11262.1| 330|Homo sapiens protein ( Homo sapiens
cDNA FLJ90397 fis, clone NT2RP2005878, moderately
similar to PUTATIVE STEROID DEHYDROGENASE KIK-I (EC
1.1.1.-). ).
Length = 330
Score = 59.7 bits (138), Expect = 8e-09
Identities = 47/171 (27%), Positives = 81/171 (47%), Gaps = 6/171 (3%)
Frame = +2
Query: 128 LSKLGAQLSLTGRNVENLQKVSKD-CDKF-ASTLSITADLTKESDIEKIIKKTIDHYGKL 301
L+ G + L RN E LQ V+KD D + T I AD + +I I++ + +
Sbjct: 87 LASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADFSSGREIYLPIREALKDKD-V 145
Query: 302 DVLVNNAGIIETGTIENTSLAQYDRL---MNTNVRSIYYLTMLAVPHLLE-SKGXXXXXX 469
+LVNN G+ T L++ D+L +N N+ + + + +P ++E KG
Sbjct: 146 GILVNNVGVFYPYPQYFTQLSE-DKLWDIINVNIAAASLMVHVVLPGMVERKKGAIVTIS 204
Query: 470 XXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTEL 622
+ P + A++ SKA +D F+R + A KG+ V + P + T +
Sbjct: 205 SGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVATSM 255
>AF237684-1|AAK15047.1| 309|Homo sapiens steroid dehydrogenase-like
protein protein.
Length = 309
Score = 59.7 bits (138), Expect = 8e-09
Identities = 47/171 (27%), Positives = 81/171 (47%), Gaps = 6/171 (3%)
Frame = +2
Query: 128 LSKLGAQLSLTGRNVENLQKVSKD-CDKF-ASTLSITADLTKESDIEKIIKKTIDHYGKL 301
L+ G + L RN E LQ V+KD D + T I AD + +I I++ + +
Sbjct: 66 LASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADFSSGREIYLPIREALKDKD-V 124
Query: 302 DVLVNNAGIIETGTIENTSLAQYDRL---MNTNVRSIYYLTMLAVPHLLE-SKGXXXXXX 469
+LVNN G+ T L++ D+L +N N+ + + + +P ++E KG
Sbjct: 125 GILVNNVGVFYPYPQYFTQLSE-DKLWDIINVNIAAASLMVHVVLPGMVERKKGAIVTIS 183
Query: 470 XXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTEL 622
+ P + A++ SKA +D F+R + A KG+ V + P + T +
Sbjct: 184 SGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVATSM 234
>BC036001-1|AAH36001.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 58.8 bits (136), Expect = 1e-08
Identities = 43/167 (25%), Positives = 74/167 (44%), Gaps = 5/167 (2%)
Frame = +2
Query: 131 SKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDV 307
+KL ++L L N L++ + C + + + D + DI KK G + +
Sbjct: 57 AKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSI 116
Query: 308 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 484
LVNNAG++ T + T Q ++ NV + ++ T +P + ++ G G
Sbjct: 117 LVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGH 176
Query: 485 RSFPGVLAYNISKASVDQFTRCVALXLAP---KGVRVNCVNPXVILT 616
S P +LAY SK + F + + LA GV+ C+ P + T
Sbjct: 177 VSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNT 223
>BC021673-1|AAH21673.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 58.8 bits (136), Expect = 1e-08
Identities = 43/167 (25%), Positives = 74/167 (44%), Gaps = 5/167 (2%)
Frame = +2
Query: 131 SKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDV 307
+KL ++L L N L++ + C + + + D + DI KK G + +
Sbjct: 57 AKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSI 116
Query: 308 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 484
LVNNAG++ T + T Q ++ NV + ++ T +P + ++ G G
Sbjct: 117 LVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGH 176
Query: 485 RSFPGVLAYNISKASVDQFTRCVALXLAP---KGVRVNCVNPXVILT 616
S P +LAY SK + F + + LA GV+ C+ P + T
Sbjct: 177 VSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNT 223
>BC016367-1|AAH16367.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 58.8 bits (136), Expect = 1e-08
Identities = 43/167 (25%), Positives = 74/167 (44%), Gaps = 5/167 (2%)
Frame = +2
Query: 131 SKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDV 307
+KL ++L L N L++ + C + + + D + DI KK G + +
Sbjct: 57 AKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSI 116
Query: 308 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 484
LVNNAG++ T + T Q ++ NV + ++ T +P + ++ G G
Sbjct: 117 LVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGH 176
Query: 485 RSFPGVLAYNISKASVDQFTRCVALXLAP---KGVRVNCVNPXVILT 616
S P +LAY SK + F + + LA GV+ C+ P + T
Sbjct: 177 VSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNT 223
>BC014327-1|AAH14327.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 58.8 bits (136), Expect = 1e-08
Identities = 43/167 (25%), Positives = 74/167 (44%), Gaps = 5/167 (2%)
Frame = +2
Query: 131 SKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDV 307
+KL ++L L N L++ + C + + + D + DI KK G + +
Sbjct: 57 AKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSI 116
Query: 308 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 484
LVNNAG++ T + T Q ++ NV + ++ T +P + ++ G G
Sbjct: 117 LVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGH 176
Query: 485 RSFPGVLAYNISKASVDQFTRCVALXLAP---KGVRVNCVNPXVILT 616
S P +LAY SK + F + + LA GV+ C+ P + T
Sbjct: 177 VSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNT 223
>AY358553-1|AAQ88917.1| 300|Homo sapiens KFLL207 protein.
Length = 300
Score = 58.8 bits (136), Expect = 1e-08
Identities = 43/167 (25%), Positives = 74/167 (44%), Gaps = 5/167 (2%)
Frame = +2
Query: 131 SKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDV 307
+KL ++L L N L++ + C + + + D + DI KK G + +
Sbjct: 57 AKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSI 116
Query: 308 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 484
LVNNAG++ T + T Q ++ NV + ++ T +P + ++ G G
Sbjct: 117 LVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGH 176
Query: 485 RSFPGVLAYNISKASVDQFTRCVALXLAP---KGVRVNCVNPXVILT 616
S P +LAY SK + F + + LA GV+ C+ P + T
Sbjct: 177 VSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNT 223
>AK075348-1|BAC11560.1| 300|Homo sapiens protein ( Homo sapiens
cDNA PSEC0029 fis, clone NT2RP1000544, highly similar to
Retinal short-chain dehydrogenase/reductase 2. ).
Length = 300
Score = 58.8 bits (136), Expect = 1e-08
Identities = 43/167 (25%), Positives = 74/167 (44%), Gaps = 5/167 (2%)
Frame = +2
Query: 131 SKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDV 307
+KL ++L L N L++ + C + + + D + DI KK G + +
Sbjct: 57 AKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSI 116
Query: 308 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 484
LVNNAG++ T + T Q ++ NV + ++ T +P + ++ G G
Sbjct: 117 LVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGH 176
Query: 485 RSFPGVLAYNISKASVDQFTRCVALXLAP---KGVRVNCVNPXVILT 616
S P +LAY SK + F + + LA GV+ C+ P + T
Sbjct: 177 VSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNT 223
>AF273056-1|AAM44459.1| 300|Homo sapiens CTCL tumor antigen
HD-CL-03 protein.
Length = 300
Score = 58.8 bits (136), Expect = 1e-08
Identities = 43/167 (25%), Positives = 74/167 (44%), Gaps = 5/167 (2%)
Frame = +2
Query: 131 SKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDV 307
+KL ++L L N L++ + C + + + D + DI KK G + +
Sbjct: 57 AKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSI 116
Query: 308 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 484
LVNNAG++ T + T Q ++ NV + ++ T +P + ++ G G
Sbjct: 117 LVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGH 176
Query: 485 RSFPGVLAYNISKASVDQFTRCVALXLAP---KGVRVNCVNPXVILT 616
S P +LAY SK + F + + LA GV+ C+ P + T
Sbjct: 177 VSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNT 223
>AF139841-1|AAP97273.1| 244|Homo sapiens carbonyl reductase II
protein.
Length = 244
Score = 58.8 bits (136), Expect = 1e-08
Identities = 37/160 (23%), Positives = 67/160 (41%), Gaps = 2/160 (1%)
Frame = +2
Query: 149 LSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI 328
L TG V + + D D + + + ++ + G +D+LVNNA +
Sbjct: 27 LHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDWEATERALGSVGPVDLLVNNAAV 86
Query: 329 IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXXGIRSFPGV 502
+ +DR N+R++ ++ +A L+ G R+
Sbjct: 87 ALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIAARGLIARGVPGAIVNVSSQCSQRAVTNH 146
Query: 503 LAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTEL 622
Y +K ++D T+ +AL L P +RVN VNP V++T +
Sbjct: 147 SVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSM 186
>AF126780-1|AAF06939.1| 300|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR2 protein.
Length = 300
Score = 58.8 bits (136), Expect = 1e-08
Identities = 43/167 (25%), Positives = 74/167 (44%), Gaps = 5/167 (2%)
Frame = +2
Query: 131 SKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDV 307
+KL ++L L N L++ + C + + + D + DI KK G + +
Sbjct: 57 AKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSI 116
Query: 308 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 484
LVNNAG++ T + T Q ++ NV + ++ T +P + ++ G G
Sbjct: 117 LVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGH 176
Query: 485 RSFPGVLAYNISKASVDQFTRCVALXLAP---KGVRVNCVNPXVILT 616
S P +LAY SK + F + + LA GV+ C+ P + T
Sbjct: 177 VSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNT 223
>BC106917-1|AAI06918.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 58.4 bits (135), Expect = 2e-08
Identities = 46/171 (26%), Positives = 81/171 (47%), Gaps = 6/171 (3%)
Frame = +2
Query: 128 LSKLGAQLSLTGRNVENLQKVSKD-CDKF-ASTLSITADLTKESDIEKIIKKTIDHYGKL 301
L+ G + L RN E LQ V+KD D + T I AD + +I I++ + +
Sbjct: 87 LASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADFSSGREIYLPIREALKDKD-V 145
Query: 302 DVLVNNAGIIETGTIENTSLAQYDRL---MNTNVRSIYYLTMLAVPHLLE-SKGXXXXXX 469
+LVNN G+ T L++ D+L +N N+ + + + +P ++E KG
Sbjct: 146 GILVNNVGVFYPYPQYFTQLSE-DKLWDIINVNIAAASLMVHVVLPGMVERKKGAIVTIS 204
Query: 470 XXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTEL 622
+ P + A++ S+A +D F+R + A KG+ V + P + T +
Sbjct: 205 SGSCCKPTPQLAAFSASRAYLDHFSRALQYEYASKGIFVQSLIPFYVATSM 255
>BC104219-1|AAI04220.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 58.4 bits (135), Expect = 2e-08
Identities = 46/171 (26%), Positives = 81/171 (47%), Gaps = 6/171 (3%)
Frame = +2
Query: 128 LSKLGAQLSLTGRNVENLQKVSKD-CDKF-ASTLSITADLTKESDIEKIIKKTIDHYGKL 301
L+ G + L RN E LQ V+KD D + T I AD + +I I++ + +
Sbjct: 87 LASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADFSSGREIYLPIREALKDKD-V 145
Query: 302 DVLVNNAGIIETGTIENTSLAQYDRL---MNTNVRSIYYLTMLAVPHLLE-SKGXXXXXX 469
+LVNN G+ T L++ D+L +N N+ + + + +P ++E KG
Sbjct: 146 GILVNNVGVFYPYPQYFTQLSE-DKLWDIINVNIAAASLMVHVVLPGMVERKKGAIVTIS 204
Query: 470 XXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTEL 622
+ P + A++ S+A +D F+R + A KG+ V + P + T +
Sbjct: 205 SGSCCKPTPQLAAFSASRAYLDHFSRALQYEYASKGIFVQSLIPFYVATSM 255
>BC018084-1|AAH18084.2| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 57.6 bits (133), Expect = 3e-08
Identities = 46/171 (26%), Positives = 80/171 (46%), Gaps = 6/171 (3%)
Frame = +2
Query: 128 LSKLGAQLSLTGRNVENLQKVSKD-CDKF-ASTLSITADLTKESDIEKIIKKTIDHYGKL 301
L+ G + L RN E LQ V+KD D + T I AD + +I I++ + +
Sbjct: 87 LASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADFSSGREIYLPIREALKDKD-V 145
Query: 302 DVLVNNAGIIETGTIENTSLAQYDRL---MNTNVRSIYYLTMLAVPHLLE-SKGXXXXXX 469
+LVNN G+ T L++ D+L +N N+ + + + +P ++E KG
Sbjct: 146 GILVNNVGVFYPYPQYFTQLSE-DKLWDIINVNIAAASLMVHVVLPGMVERKKGAIVTIS 204
Query: 470 XXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTEL 622
+ P + A++ SKA +D F+R + A KG+ V + P + +
Sbjct: 205 SGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVAASM 255
>BT006881-1|AAP35527.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 57.2 bits (132), Expect = 4e-08
Identities = 36/160 (22%), Positives = 66/160 (41%), Gaps = 2/160 (1%)
Frame = +2
Query: 149 LSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI 328
L TG V + + D D + + + ++ + G +D+LVNNA +
Sbjct: 27 LHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDWEATERALGSVGPVDLLVNNAAV 86
Query: 329 IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXXGIRSFPGV 502
+ +DR N+R++ ++ + L+ G R+
Sbjct: 87 ALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNH 146
Query: 503 LAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTEL 622
Y +K ++D T+ +AL L P +RVN VNP V++T +
Sbjct: 147 SVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSM 186
>BC003018-1|AAH03018.1| 243|Homo sapiens Unknown (protein for
IMAGE:2822726) protein.
Length = 243
Score = 57.2 bits (132), Expect = 4e-08
Identities = 36/160 (22%), Positives = 66/160 (41%), Gaps = 2/160 (1%)
Frame = +2
Query: 149 LSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI 328
L TG V + + D D + + + ++ + G +D+LVNNA +
Sbjct: 26 LHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDWEATERALGSVGPVDLLVNNAAV 85
Query: 329 IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXXGIRSFPGV 502
+ +DR N+R++ ++ + L+ G R+
Sbjct: 86 ALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNH 145
Query: 503 LAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTEL 622
Y +K ++D T+ +AL L P +RVN VNP V++T +
Sbjct: 146 SVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSM 185
>BC001470-1|AAH01470.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 57.2 bits (132), Expect = 4e-08
Identities = 36/160 (22%), Positives = 66/160 (41%), Gaps = 2/160 (1%)
Frame = +2
Query: 149 LSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI 328
L TG V + + D D + + + ++ + G +D+LVNNA +
Sbjct: 27 LHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDWEATERALGSVGPVDLLVNNAAV 86
Query: 329 IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXXGIRSFPGV 502
+ +DR N+R++ ++ + L+ G R+
Sbjct: 87 ALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNH 146
Query: 503 LAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTEL 622
Y +K ++D T+ +AL L P +RVN VNP V++T +
Sbjct: 147 SVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSM 186
>AF515625-1|AAM54026.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 57.2 bits (132), Expect = 4e-08
Identities = 36/160 (22%), Positives = 66/160 (41%), Gaps = 2/160 (1%)
Frame = +2
Query: 149 LSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI 328
L TG V + + D D + + + ++ + G +D+LVNNA +
Sbjct: 27 LHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDWEATERALGSVGPVDLLVNNAAV 86
Query: 329 IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXXGIRSFPGV 502
+ +DR N+R++ ++ + L+ G R+
Sbjct: 87 ALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNH 146
Query: 503 LAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTEL 622
Y +K ++D T+ +AL L P +RVN VNP V++T +
Sbjct: 147 SVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSM 186
>AF515624-1|AAO15991.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 57.2 bits (132), Expect = 4e-08
Identities = 36/160 (22%), Positives = 66/160 (41%), Gaps = 2/160 (1%)
Frame = +2
Query: 149 LSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI 328
L TG V + + D D + + + ++ + G +D+LVNNA +
Sbjct: 27 LHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDWEATERALGSVGPVDLLVNNAAV 86
Query: 329 IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXXGIRSFPGV 502
+ +DR N+R++ ++ + L+ G R+
Sbjct: 87 ALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNH 146
Query: 503 LAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTEL 622
Y +K ++D T+ +AL L P +RVN VNP V++T +
Sbjct: 147 SVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSM 186
>AF515623-1|AAN59786.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 57.2 bits (132), Expect = 4e-08
Identities = 36/160 (22%), Positives = 66/160 (41%), Gaps = 2/160 (1%)
Frame = +2
Query: 149 LSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI 328
L TG V + + D D + + + ++ + G +D+LVNNA +
Sbjct: 27 LHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDWEATERALGSVGPVDLLVNNAAV 86
Query: 329 IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXXGIRSFPGV 502
+ +DR N+R++ ++ + L+ G R+
Sbjct: 87 ALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNH 146
Query: 503 LAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTEL 622
Y +K ++D T+ +AL L P +RVN VNP V++T +
Sbjct: 147 SVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSM 186
>AF113123-1|AAF14864.1| 244|Homo sapiens carbonyl reductase
protein.
Length = 244
Score = 57.2 bits (132), Expect = 4e-08
Identities = 36/160 (22%), Positives = 66/160 (41%), Gaps = 2/160 (1%)
Frame = +2
Query: 149 LSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI 328
L TG V + + D D + + + ++ + G +D+LVNNA +
Sbjct: 27 LHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDWEATERALGSVGPVDLLVNNAAV 86
Query: 329 IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXXGIRSFPGV 502
+ +DR N+R++ ++ + L+ G R+
Sbjct: 87 ALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNH 146
Query: 503 LAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTEL 622
Y +K ++D T+ +AL L P +RVN VNP V++T +
Sbjct: 147 SVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSM 186
>AB013846-1|BAB64299.1| 244|Homo sapiens kidney dicarbonyl
reductase protein.
Length = 244
Score = 57.2 bits (132), Expect = 4e-08
Identities = 36/160 (22%), Positives = 66/160 (41%), Gaps = 2/160 (1%)
Frame = +2
Query: 149 LSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI 328
L TG V + + D D + + + ++ + G +D+LVNNA +
Sbjct: 27 LHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDWEATERALGSVGPVDLLVNNAAV 86
Query: 329 IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXXGIRSFPGV 502
+ +DR N+R++ ++ + L+ G R+
Sbjct: 87 ALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNH 146
Query: 503 LAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTEL 622
Y +K ++D T+ +AL L P +RVN VNP V++T +
Sbjct: 147 SVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSM 186
>M93107-1|AAA58352.1| 343|Homo sapiens (R)-3-hydroxybutyrate
dehydrogenase protein.
Length = 343
Score = 56.8 bits (131), Expect = 6e-08
Identities = 32/98 (32%), Positives = 48/98 (48%)
Frame = +2
Query: 308 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIR 487
LVNNAGI G +E TSL Y ++ N+ +T +P + +KG G
Sbjct: 141 LVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRM 200
Query: 488 SFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNP 601
+ P Y I+K V+ F+ C+ + P GV+V+ V P
Sbjct: 201 ANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEP 238
>M76665-1|AAC31757.1| 292|Homo sapiens 11-beta-hydroxysteroid
dehydrogenase protein.
Length = 292
Score = 56.8 bits (131), Expect = 6e-08
Identities = 43/160 (26%), Positives = 69/160 (43%), Gaps = 2/160 (1%)
Frame = +2
Query: 68 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKF--ASTLSITADL 241
GK V L+K+GA + +T R+ E LQKV C + AS I +
Sbjct: 34 GKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTM 93
Query: 242 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTML 421
+ E+ + + G LD+L+ N + + + + + M N S LT+
Sbjct: 94 EDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVA 153
Query: 422 AVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQF 541
A+P L +S G G ++P V AY+ SK ++D F
Sbjct: 154 ALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGF 193
>L76465-1|AAA89175.1| 266|Homo sapiens NAD+-dependent
15-hydroxyprostaglandin dehydrogenase protein.
Length = 266
Score = 56.8 bits (131), Expect = 6e-08
Identities = 49/198 (24%), Positives = 84/198 (42%), Gaps = 9/198 (4%)
Frame = +2
Query: 56 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVE-NLQKVSKDCDKFA--STLS 226
M+ GKV L GA+++L N+E +Q + ++F TL
Sbjct: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALHEQFEPQKTLF 60
Query: 227 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 406
I D+ + + +K +DH+G+LD+LVNNAG+ + +++ + N+ S+
Sbjct: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV--------NNEKNWEKTLQINLVSVI 112
Query: 407 YLTMLAVPHLLESK----GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALX--LA 568
T L + ++ + G G+ Y SK + FTR AL L
Sbjct: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172
Query: 569 PKGVRVNCVNPXVILTEL 622
GVR+N + P + T +
Sbjct: 173 NSGVRLNAICPGFVNTAI 190
>J05594-1|AAA89174.1| 266|Homo sapiens NAD+-dependent
15-hydroxyprostaglandin dehydrogenase protein.
Length = 266
Score = 56.8 bits (131), Expect = 6e-08
Identities = 49/198 (24%), Positives = 84/198 (42%), Gaps = 9/198 (4%)
Frame = +2
Query: 56 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVE-NLQKVSKDCDKFA--STLS 226
M+ GKV L GA+++L N+E +Q + ++F TL
Sbjct: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALHEQFEPQKTLF 60
Query: 227 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 406
I D+ + + +K +DH+G+LD+LVNNAG+ + +++ + N+ S+
Sbjct: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV--------NNEKNWEKTLQINLVSVI 112
Query: 407 YLTMLAVPHLLESK----GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALX--LA 568
T L + ++ + G G+ Y SK + FTR AL L
Sbjct: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172
Query: 569 PKGVRVNCVNPXVILTEL 622
GVR+N + P + T +
Sbjct: 173 NSGVRLNAICPGFVNTAI 190
>DQ903072-1|ABI75347.1| 266|Homo sapiens hydroxyprostaglandin
dehydrogenase 15-(NAD) protein.
Length = 266
Score = 56.8 bits (131), Expect = 6e-08
Identities = 49/198 (24%), Positives = 84/198 (42%), Gaps = 9/198 (4%)
Frame = +2
Query: 56 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVE-NLQKVSKDCDKFA--STLS 226
M+ GKV L GA+++L N+E +Q + ++F TL
Sbjct: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60
Query: 227 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 406
I D+ + + +K +DH+G+LD+LVNNAG+ + +++ + N+ S+
Sbjct: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV--------NNEKNWEKTLQINLVSVI 112
Query: 407 YLTMLAVPHLLESK----GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALX--LA 568
T L + ++ + G G+ Y SK + FTR AL L
Sbjct: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172
Query: 569 PKGVRVNCVNPXVILTEL 622
GVR+N + P + T +
Sbjct: 173 NSGVRLNAICPGFVNTAI 190
>BC019317-1|AAH19317.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 56.8 bits (131), Expect = 6e-08
Identities = 32/98 (32%), Positives = 48/98 (48%)
Frame = +2
Query: 308 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIR 487
LVNNAGI G +E TSL Y ++ N+ +T +P + +KG G
Sbjct: 141 LVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRM 200
Query: 488 SFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNP 601
+ P Y I+K V+ F+ C+ + P GV+V+ V P
Sbjct: 201 ANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEP 238
>BC018986-1|AAH18986.1| 266|Homo sapiens hydroxyprostaglandin
dehydrogenase 15-(NAD) protein.
Length = 266
Score = 56.8 bits (131), Expect = 6e-08
Identities = 49/198 (24%), Positives = 84/198 (42%), Gaps = 9/198 (4%)
Frame = +2
Query: 56 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVE-NLQKVSKDCDKFA--STLS 226
M+ GKV L GA+++L N+E +Q + ++F TL
Sbjct: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60
Query: 227 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 406
I D+ + + +K +DH+G+LD+LVNNAG+ + +++ + N+ S+
Sbjct: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV--------NNEKNWEKTLQINLVSVI 112
Query: 407 YLTMLAVPHLLESK----GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALX--LA 568
T L + ++ + G G+ Y SK + FTR AL L
Sbjct: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172
Query: 569 PKGVRVNCVNPXVILTEL 622
GVR+N + P + T +
Sbjct: 173 NSGVRLNAICPGFVNTAI 190
>BC012593-1|AAH12593.1| 292|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 1 protein.
Length = 292
Score = 56.8 bits (131), Expect = 6e-08
Identities = 43/160 (26%), Positives = 69/160 (43%), Gaps = 2/160 (1%)
Frame = +2
Query: 68 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKF--ASTLSITADL 241
GK V L+K+GA + +T R+ E LQKV C + AS I +
Sbjct: 34 GKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTM 93
Query: 242 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTML 421
+ E+ + + G LD+L+ N + + + + + M N S LT+
Sbjct: 94 EDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVA 153
Query: 422 AVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQF 541
A+P L +S G G ++P V AY+ SK ++D F
Sbjct: 154 ALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGF 193
>BC011964-1|AAH11964.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 56.8 bits (131), Expect = 6e-08
Identities = 32/98 (32%), Positives = 48/98 (48%)
Frame = +2
Query: 308 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIR 487
LVNNAGI G +E TSL Y ++ N+ +T +P + +KG G
Sbjct: 141 LVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRM 200
Query: 488 SFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNP 601
+ P Y I+K V+ F+ C+ + P GV+V+ V P
Sbjct: 201 ANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEP 238
>BC005844-1|AAH05844.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 56.8 bits (131), Expect = 6e-08
Identities = 32/98 (32%), Positives = 48/98 (48%)
Frame = +2
Query: 308 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIR 487
LVNNAGI G +E TSL Y ++ N+ +T +P + +KG G
Sbjct: 141 LVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRM 200
Query: 488 SFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNP 601
+ P Y I+K V+ F+ C+ + P GV+V+ V P
Sbjct: 201 ANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEP 238
>AY044084-1|AAK83653.1| 292|Homo sapiens 11-beta hydroxysteroid
dehydrogenase type 1 protein.
Length = 292
Score = 56.8 bits (131), Expect = 6e-08
Identities = 43/160 (26%), Positives = 69/160 (43%), Gaps = 2/160 (1%)
Frame = +2
Query: 68 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKF--ASTLSITADL 241
GK V L+K+GA + +T R+ E LQKV C + AS I +
Sbjct: 34 GKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTM 93
Query: 242 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTML 421
+ E+ + + G LD+L+ N + + + + + M N S LT+
Sbjct: 94 EDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVA 153
Query: 422 AVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQF 541
A+P L +S G G ++P V AY+ SK ++D F
Sbjct: 154 ALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGF 193
>AL031316-4|CAI20063.1| 292|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 1 protein.
Length = 292
Score = 56.8 bits (131), Expect = 6e-08
Identities = 43/160 (26%), Positives = 69/160 (43%), Gaps = 2/160 (1%)
Frame = +2
Query: 68 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKF--ASTLSITADL 241
GK V L+K+GA + +T R+ E LQKV C + AS I +
Sbjct: 34 GKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTM 93
Query: 242 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTML 421
+ E+ + + G LD+L+ N + + + + + M N S LT+
Sbjct: 94 EDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVA 153
Query: 422 AVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQF 541
A+P L +S G G ++P V AY+ SK ++D F
Sbjct: 154 ALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGF 193
>AL022398-8|CAA18541.2| 292|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 1 protein.
Length = 292
Score = 56.8 bits (131), Expect = 6e-08
Identities = 43/160 (26%), Positives = 69/160 (43%), Gaps = 2/160 (1%)
Frame = +2
Query: 68 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKF--ASTLSITADL 241
GK V L+K+GA + +T R+ E LQKV C + AS I +
Sbjct: 34 GKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTM 93
Query: 242 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTML 421
+ E+ + + G LD+L+ N + + + + + M N S LT+
Sbjct: 94 EDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVA 153
Query: 422 AVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQF 541
A+P L +S G G ++P V AY+ SK ++D F
Sbjct: 154 ALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGF 193
>BC008650-1|AAH08650.1| 300|Homo sapiens HSD17B11 protein protein.
Length = 300
Score = 56.4 bits (130), Expect = 8e-08
Identities = 42/167 (25%), Positives = 73/167 (43%), Gaps = 5/167 (2%)
Frame = +2
Query: 131 SKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDV 307
+KL ++L L N L++ + C + + + D + DI K G + +
Sbjct: 57 AKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKNCKAEIGDVSI 116
Query: 308 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 484
LVNNAG++ T + T Q ++ NV + ++ T +P + ++ G G
Sbjct: 117 LVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGH 176
Query: 485 RSFPGVLAYNISKASVDQFTRCVALXLAP---KGVRVNCVNPXVILT 616
S P +LAY SK + F + + LA GV+ C+ P + T
Sbjct: 177 VSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNT 223
>BC015943-1|AAH15943.1| 313|Homo sapiens DHRS1 protein protein.
Length = 313
Score = 55.2 bits (127), Expect = 2e-07
Identities = 41/174 (23%), Positives = 80/174 (45%), Gaps = 9/174 (5%)
Frame = +2
Query: 128 LSKLGAQLSLTGRNVENLQKVSKDCDKFAST-LSITADLTKESDIEKIIKKTI-DHYGKL 301
L K GA + +TGR+++ L+ V+++ + + D ++ES++ + ++ + G+L
Sbjct: 27 LCKAGATVYITGRHLDTLRVVAQEAQSLGGQCVPVVCDSSQESEVRSLFEQVDREQQGRL 86
Query: 302 DVLVNN--AGIIETGTIEN-----TSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXX 460
DVLVNN AG+ N T + +D + N +R Y+ ++ ++ +
Sbjct: 87 DVLVNNAYAGVQTILNTRNKAFWETPASMWDDINNVGLRGHYFCSVYGARLMVPAGQGLI 146
Query: 461 XXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTEL 622
G + + Y + KA+ D+ A L GV + P ++ TEL
Sbjct: 147 VVISSPGSLQYMFNVPYGVGKAACDKLAADCAHELRRHGVSCVSLWPGIVQTEL 200
>BC014057-1|AAH14057.1| 313|Homo sapiens DHRS1 protein protein.
Length = 313
Score = 55.2 bits (127), Expect = 2e-07
Identities = 41/174 (23%), Positives = 80/174 (45%), Gaps = 9/174 (5%)
Frame = +2
Query: 128 LSKLGAQLSLTGRNVENLQKVSKDCDKFAST-LSITADLTKESDIEKIIKKTI-DHYGKL 301
L K GA + +TGR+++ L+ V+++ + + D ++ES++ + ++ + G+L
Sbjct: 27 LCKAGATVYITGRHLDTLRVVAQEAQSLGGQCVPVVCDSSQESEVRSLFEQVDREQQGRL 86
Query: 302 DVLVNN--AGIIETGTIEN-----TSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXX 460
DVLVNN AG+ N T + +D + N +R Y+ ++ ++ +
Sbjct: 87 DVLVNNAYAGVQTILNTRNKAFWETPASMWDDINNVGLRGHYFCSVYGARLMVPAGQGLI 146
Query: 461 XXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTEL 622
G + + Y + KA+ D+ A L GV + P ++ TEL
Sbjct: 147 VVISSPGSLQYMFNVLYGVGKAACDKLAADCAHELRRHGVSCVSLWPGIVQTEL 200
>AK058159-1|BAB71694.1| 313|Homo sapiens protein ( Homo sapiens
cDNA FLJ25430 fis, clone TST06262. ).
Length = 313
Score = 55.2 bits (127), Expect = 2e-07
Identities = 41/174 (23%), Positives = 80/174 (45%), Gaps = 9/174 (5%)
Frame = +2
Query: 128 LSKLGAQLSLTGRNVENLQKVSKDCDKFAST-LSITADLTKESDIEKIIKKTI-DHYGKL 301
L K GA + +TGR+++ L+ V+++ + + D ++ES++ + ++ + G+L
Sbjct: 27 LCKAGATVYITGRHLDTLRVVAQEAQSLGGQCVPVVCDSSQESEVRSLFEQVDREQQGRL 86
Query: 302 DVLVNN--AGIIETGTIEN-----TSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXX 460
DVLVNN AG+ N T + +D + N +R Y+ ++ ++ +
Sbjct: 87 DVLVNNAYAGVQTILNTRNKAFWETPASMWDDINNVGLRGHYFCSVYGARLMVPAGQGLI 146
Query: 461 XXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTEL 622
G + + Y + KA+ D+ A L GV + P ++ TEL
Sbjct: 147 VVISSPGSLQYMFNVPYGVGKAACDKLAADCAHELRRHGVSCVSLWPGIVQTEL 200
>AF418205-1|AAN32660.1| 313|Homo sapiens dehydrogenase/reductase
SDR family member 1 protein.
Length = 313
Score = 55.2 bits (127), Expect = 2e-07
Identities = 41/174 (23%), Positives = 80/174 (45%), Gaps = 9/174 (5%)
Frame = +2
Query: 128 LSKLGAQLSLTGRNVENLQKVSKDCDKFAST-LSITADLTKESDIEKIIKKTI-DHYGKL 301
L K GA + +TGR+++ L+ V+++ + + D ++ES++ + ++ + G+L
Sbjct: 27 LCKAGATVYITGRHLDTLRVVAQEAQSLGGQCVPVVCDSSQESEVRSLFEQVDREQQGRL 86
Query: 302 DVLVNN--AGIIETGTIEN-----TSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXX 460
DVLVNN AG+ N T + +D + N +R Y+ ++ ++ +
Sbjct: 87 DVLVNNAYAGVQTILNTRNKAFWETPASMWDDINNVGLRGHYFCSVYGARLMVPAGQGLI 146
Query: 461 XXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTEL 622
G + + Y + KA+ D+ A L GV + P ++ TEL
Sbjct: 147 VVISSPGSLQYMFNVPYGVGKAACDKLAADCAHELRRHGVSCVSLWPGIVQTEL 200
>U26726-1|AAC50356.1| 405|Homo sapiens 11-beta-hydroxysteroid
dehydrogenase type 2 protein.
Length = 405
Score = 54.4 bits (125), Expect = 3e-07
Identities = 41/131 (31%), Positives = 58/131 (44%), Gaps = 3/131 (2%)
Frame = +2
Query: 236 DLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIY 406
DLTK DI ++++ T H + LVNNAG E E + +A + M N
Sbjct: 138 DLTKPGDISRVLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGAL 197
Query: 407 YLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 586
LT +P L S+G G +P + AY SKA+V + L P GV+V
Sbjct: 198 ELTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVKV 257
Query: 587 NCVNPXVILTE 619
+ + P TE
Sbjct: 258 SIIQPGCFKTE 268
>EF694683-1|ABS29267.1| 405|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 2 protein.
Length = 405
Score = 54.4 bits (125), Expect = 3e-07
Identities = 41/131 (31%), Positives = 58/131 (44%), Gaps = 3/131 (2%)
Frame = +2
Query: 236 DLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIY 406
DLTK DI ++++ T H + LVNNAG E E + +A + M N
Sbjct: 138 DLTKPGDISRVLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGAL 197
Query: 407 YLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 586
LT +P L S+G G +P + AY SKA+V + L P GV+V
Sbjct: 198 ELTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVKV 257
Query: 587 NCVNPXVILTE 619
+ + P TE
Sbjct: 258 SIIQPGCFKTE 268
>BC064536-1|AAH64536.1| 405|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 2 protein.
Length = 405
Score = 54.4 bits (125), Expect = 3e-07
Identities = 41/131 (31%), Positives = 58/131 (44%), Gaps = 3/131 (2%)
Frame = +2
Query: 236 DLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIY 406
DLTK DI ++++ T H + LVNNAG E E + +A + M N
Sbjct: 138 DLTKPGDISRVLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGAL 197
Query: 407 YLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 586
LT +P L S+G G +P + AY SKA+V + L P GV+V
Sbjct: 198 ELTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVKV 257
Query: 587 NCVNPXVILTE 619
+ + P TE
Sbjct: 258 SIIQPGCFKTE 268
>BC036780-1|AAH36780.1| 405|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 2 protein.
Length = 405
Score = 54.4 bits (125), Expect = 3e-07
Identities = 41/131 (31%), Positives = 58/131 (44%), Gaps = 3/131 (2%)
Frame = +2
Query: 236 DLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIY 406
DLTK DI ++++ T H + LVNNAG E E + +A + M N
Sbjct: 138 DLTKPGDISRVLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGAL 197
Query: 407 YLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 586
LT +P L S+G G +P + AY SKA+V + L P GV+V
Sbjct: 198 ELTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVKV 257
Query: 587 NCVNPXVILTE 619
+ + P TE
Sbjct: 258 SIIQPGCFKTE 268
>X87176-1|CAA60643.1| 736|Homo sapiens 17beta-hydroxysteroid
dehydrogenase protein.
Length = 736
Score = 54.0 bits (124), Expect = 4e-07
Identities = 36/159 (22%), Positives = 67/159 (42%), Gaps = 1/159 (0%)
Frame = +2
Query: 128 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 307
++ LG G+ KV ++ + D +E EK++K +D +G++DV
Sbjct: 38 VNDLGGDFKGVGKGSLAADKVVEEIRRRGGKAVANYDSVEEG--EKVVKTALDAFGRIDV 95
Query: 308 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 484
+VNNAGI+ + S +D + ++R + +T A H+ + K G GI
Sbjct: 96 VVNNAGILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGI 155
Query: 485 RSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNP 601
G Y+ +K + +A+ + N + P
Sbjct: 156 YGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAP 194
>U14631-1|AAA91969.1| 405|Homo sapiens 11 beta-hydroxysteroid
dehydrogenase type II protein.
Length = 405
Score = 54.0 bits (124), Expect = 4e-07
Identities = 41/131 (31%), Positives = 58/131 (44%), Gaps = 3/131 (2%)
Frame = +2
Query: 236 DLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIY 406
DLTK DI ++++ T H + LVNNAG E E + +A + M N
Sbjct: 138 DLTKPGDISRLLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGAL 197
Query: 407 YLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 586
LT +P L S+G G +P + AY SKA+V + L P GV+V
Sbjct: 198 ELTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVKV 257
Query: 587 NCVNPXVILTE 619
+ + P TE
Sbjct: 258 SIIQPGCFKTE 268
>BC003098-1|AAH03098.1| 736|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 4 protein.
Length = 736
Score = 54.0 bits (124), Expect = 4e-07
Identities = 36/159 (22%), Positives = 67/159 (42%), Gaps = 1/159 (0%)
Frame = +2
Query: 128 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 307
++ LG G+ KV ++ + D +E EK++K +D +G++DV
Sbjct: 38 VNDLGGDFKGVGKGSLAADKVVEEIRRRGGKAVANYDSVEEG--EKVVKTALDAFGRIDV 95
Query: 308 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 484
+VNNAGI+ + S +D + ++R + +T A H+ + K G GI
Sbjct: 96 VVNNAGILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGI 155
Query: 485 RSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNP 601
G Y+ +K + +A+ + N + P
Sbjct: 156 YGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAP 194
>AF057740-1|AAD08652.1| 736|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase IV protein.
Length = 736
Score = 54.0 bits (124), Expect = 4e-07
Identities = 36/159 (22%), Positives = 67/159 (42%), Gaps = 1/159 (0%)
Frame = +2
Query: 128 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 307
++ LG G+ KV ++ + D +E EK++K +D +G++DV
Sbjct: 38 VNDLGGDFKGVGKGSLAADKVVEEIRRRGGKAVANYDSVEEG--EKVVKTALDAFGRIDV 95
Query: 308 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 484
+VNNAGI+ + S +D + ++R + +T A H+ + K G GI
Sbjct: 96 VVNNAGILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGI 155
Query: 485 RSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNP 601
G Y+ +K + +A+ + N + P
Sbjct: 156 YGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAP 194
>U27317-1|AAB48544.1| 405|Homo sapiens 11 beta-hydroxysteroid
dehydrogenase 2 protein.
Length = 405
Score = 53.2 bits (122), Expect = 7e-07
Identities = 41/131 (31%), Positives = 57/131 (43%), Gaps = 3/131 (2%)
Frame = +2
Query: 236 DLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIY 406
DLTK DI + ++ T H + LVNNAG E E + +A + M N
Sbjct: 138 DLTKPGDISRFLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGAL 197
Query: 407 YLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 586
LT +P L S+G G +P + AY SKA+V + L P GV+V
Sbjct: 198 ELTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVKV 257
Query: 587 NCVNPXVILTE 619
+ + P TE
Sbjct: 258 SIIQPGCFKTE 268
>BC095451-1|AAH95451.1| 418|Homo sapiens hydroxysteroid
dehydrogenase like 2 protein.
Length = 418
Score = 52.4 bits (120), Expect = 1e-06
Identities = 25/76 (32%), Positives = 38/76 (50%)
Frame = +2
Query: 221 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 400
L D+ E I ++K I +G +D+LVNNA I +T + D +MN N R
Sbjct: 69 LPCIVDVRDEQQISAAVEKAIKKFGGIDILVNNASAISLTNTLDTPTKRLDLMMNVNTRG 128
Query: 401 IYYLTMLAVPHLLESK 448
Y + +P+L +SK
Sbjct: 129 TYLASKACIPYLKKSK 144
>AY313894-1|AAP83166.1| 315|Homo sapiens short-chain
dehydrogenase/reductase 10e protein.
Length = 315
Score = 52.4 bits (120), Expect = 1e-06
Identities = 43/140 (30%), Positives = 61/140 (43%), Gaps = 3/140 (2%)
Frame = +2
Query: 131 SKLGAQLSLTGRNVENLQKVSKDCDKFAS--TLSITADLTKESDIEKIIKKTIDHYGKLD 304
++LG+ L LT LQKV +C K + I AD+ E +++ +D G LD
Sbjct: 50 ARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLD 109
Query: 305 VLV-NNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 481
LV N+ G GT + A LM N S LT A+P L +SKG G
Sbjct: 110 YLVLNHIGGAPAGTRARSPQATR-WLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLG 168
Query: 482 IRSFPGVLAYNISKASVDQF 541
Y+ +K ++D F
Sbjct: 169 RVPTSFSTPYSAAKFALDGF 188
>AY268352-1|AAP42286.1| 286|Homo sapiens short-chain
dehydrogenase/reductase 10b protein.
Length = 286
Score = 52.4 bits (120), Expect = 1e-06
Identities = 43/140 (30%), Positives = 61/140 (43%), Gaps = 3/140 (2%)
Frame = +2
Query: 131 SKLGAQLSLTGRNVENLQKVSKDCDKFAS--TLSITADLTKESDIEKIIKKTIDHYGKLD 304
++LG+ L LT LQKV +C K + I AD+ E +++ +D G LD
Sbjct: 50 ARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLD 109
Query: 305 VLV-NNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 481
LV N+ G GT + A LM N S LT A+P L +SKG G
Sbjct: 110 YLVLNHIGGAPAGTRARSPQATR-WLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLG 168
Query: 482 IRSFPGVLAYNISKASVDQF 541
Y+ +K ++D F
Sbjct: 169 RVPTSFSTPYSAAKFALDGF 188
>AY093428-1|AAM14670.1| 418|Homo sapiens hydroxysteroid
dehydrogenase-like protein protein.
Length = 418
Score = 52.4 bits (120), Expect = 1e-06
Identities = 25/76 (32%), Positives = 38/76 (50%)
Frame = +2
Query: 221 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 400
L D+ E I ++K I +G +D+LVNNA I +T + D +MN N R
Sbjct: 69 LPCIVDVRDEQQISAAVEKAIKKFGGIDILVNNASAISLTNTLDTPTKRLDLMMNVNTRG 128
Query: 401 IYYLTMLAVPHLLESK 448
Y + +P+L +SK
Sbjct: 129 TYLASKACIPYLKKSK 144
>AL162732-1|CAM17152.1| 418|Homo sapiens hydroxysteroid
dehydrogenase like 2 protein.
Length = 418
Score = 52.4 bits (120), Expect = 1e-06
Identities = 25/76 (32%), Positives = 38/76 (50%)
Frame = +2
Query: 221 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 400
L D+ E I ++K I +G +D+LVNNA I +T + D +MN N R
Sbjct: 69 LPCIVDVRDEQQISAAVEKAIKKFGGIDILVNNASAISLTNTLDTPTKRLDLMMNVNTRG 128
Query: 401 IYYLTMLAVPHLLESK 448
Y + +P+L +SK
Sbjct: 129 TYLASKACIPYLKKSK 144
>CR457309-1|CAG33590.1| 173|Homo sapiens DHRS6 protein.
Length = 173
Score = 51.6 bits (118), Expect = 2e-06
Identities = 34/127 (26%), Positives = 58/127 (45%)
Frame = +2
Query: 68 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTK 247
GKV+ ++ GA++ T N LQ++ +K+ + D+TK
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL----EKYPGIQTRVLDVTK 61
Query: 248 ESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAV 427
+ I++ + +LDVL N AG + GT+ + +D MN NVRS+Y + +
Sbjct: 62 KKQIDQFASEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFL 117
Query: 428 PHLLESK 448
P +L K
Sbjct: 118 PKMLAQK 124
>BC037277-1|AAH37277.1| 173|Homo sapiens BDH2 protein protein.
Length = 173
Score = 51.6 bits (118), Expect = 2e-06
Identities = 34/127 (26%), Positives = 58/127 (45%)
Frame = +2
Query: 68 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTK 247
GKV+ ++ GA++ T N LQ++ +K+ + D+TK
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL----EKYPGIQTRVLDVTK 61
Query: 248 ESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAV 427
+ I++ + +LDVL N AG + GT+ + +D MN NVRS+Y + +
Sbjct: 62 KKQIDQFANEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFL 117
Query: 428 PHLLESK 448
P +L K
Sbjct: 118 PKMLAQK 124
>AK023323-1|BAB14526.1| 173|Homo sapiens protein ( Homo sapiens
cDNA FLJ13261 fis, clone OVARC1000885, weakly similar to
OXIDOREDUCTASE UCPA (EC 1.-.-.-). ).
Length = 173
Score = 51.6 bits (118), Expect = 2e-06
Identities = 34/127 (26%), Positives = 58/127 (45%)
Frame = +2
Query: 68 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTK 247
GKV+ ++ GA++ T N LQ++ +K+ + D+TK
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL----EKYPGIQTRVLDVTK 61
Query: 248 ESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAV 427
+ I++ + +LDVL N AG + GT+ + +D MN NVRS+Y + +
Sbjct: 62 KKQIDQFANEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFL 117
Query: 428 PHLLESK 448
P +L K
Sbjct: 118 PKMLAQK 124
>DQ325464-1|ABC61320.1| 244|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase B1 isoform protein.
Length = 244
Score = 50.4 bits (115), Expect = 5e-06
Identities = 33/104 (31%), Positives = 54/104 (51%), Gaps = 6/104 (5%)
Frame = +2
Query: 323 GIIETGTIENTSLAQ-YDRLMNT----NVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIR 487
G+ TGT+ + A+ +RL+ T NV++ +T VP + + G
Sbjct: 80 GLSVTGTVCHVGKAEDRERLVATTLDINVKAPALMTKAVVPEMEKRGGGSVVIVSSIAAF 139
Query: 488 S-FPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILT 616
S PG YN+SK ++ T+ +A+ LAP+ +RVNC+ P +I T
Sbjct: 140 SPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLAPGLIKT 183
>BC002731-1|AAH02731.2| 260|Homo sapiens short-chain
dehydrogenase/reductase protein.
Length = 260
Score = 49.2 bits (112), Expect = 1e-05
Identities = 41/174 (23%), Positives = 76/174 (43%), Gaps = 10/174 (5%)
Frame = +2
Query: 128 LSKLGAQLSLTGRNVENLQKVSKDCDK--FASTL-SITADLTKESDIEKIIKKTIDHYGK 298
L + G ++ R V N+++++ +C + TL DL+ E DI + +
Sbjct: 31 LVQQGLKVVGCARTVGNIEELAAECKSAGYPGTLIPYRCDLSNEEDILSMFSAIRSQHSG 90
Query: 299 LDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE---SKGXXXXXX 469
+D+ +NNAG+ T+ + S + + + N NV ++ T A + E G
Sbjct: 91 VDICINNAGLARPDTLLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNVDDGHIININ 150
Query: 470 XXXGIRSFPGVLA--YNISKASVDQFTRCVALXL--APKGVRVNCVNPXVILTE 619
G R P + Y+ +K +V T + L A +R C++P V+ T+
Sbjct: 151 SMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREAQTHIRATCISPGVVETQ 204
>AY358712-1|AAQ89074.1| 260|Homo sapiens ARPG836 protein.
Length = 260
Score = 49.2 bits (112), Expect = 1e-05
Identities = 41/174 (23%), Positives = 76/174 (43%), Gaps = 10/174 (5%)
Frame = +2
Query: 128 LSKLGAQLSLTGRNVENLQKVSKDCDK--FASTL-SITADLTKESDIEKIIKKTIDHYGK 298
L + G ++ R V N+++++ +C + TL DL+ E DI + +
Sbjct: 31 LVQQGLKVVGCARTVGNIEELAAECKSAGYPGTLIPYRCDLSNEEDILSMFSAIRSQHSG 90
Query: 299 LDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE---SKGXXXXXX 469
+D+ +NNAG+ T+ + S + + + N NV ++ T A + E G
Sbjct: 91 VDICINNAGLARPDTLLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNVDDGHIININ 150
Query: 470 XXXGIRSFPGVLA--YNISKASVDQFTRCVALXL--APKGVRVNCVNPXVILTE 619
G R P + Y+ +K +V T + L A +R C++P V+ T+
Sbjct: 151 SMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREAQTHIRATCISPGVVETQ 204
>Z97054-8|CAI42653.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 261
Score = 48.0 bits (109), Expect = 3e-05
Identities = 36/143 (25%), Positives = 64/143 (44%), Gaps = 13/143 (9%)
Frame = +2
Query: 233 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 394
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 395 RSIYYLTMLAVPHLLESK----GXXXXXXXXXGIRSFPGVL---AYNISKASVDQFTRCV 553
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182
Query: 554 ALXLAPKGVRVNCVNPXVILTEL 622
A LAP G+RV + P + T L
Sbjct: 183 ARDLAPIGIRVMTIAPGLFGTPL 205
>U96132-1|AAC51812.1| 261|Homo sapiens amyloid beta-peptide binding
protein protein.
Length = 261
Score = 48.0 bits (109), Expect = 3e-05
Identities = 36/143 (25%), Positives = 64/143 (44%), Gaps = 13/143 (9%)
Frame = +2
Query: 233 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 394
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 395 RSIYYLTMLAVPHLLESK----GXXXXXXXXXGIRSFPGVL---AYNISKASVDQFTRCV 553
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182
Query: 554 ALXLAPKGVRVNCVNPXVILTEL 622
A LAP G+RV + P + T L
Sbjct: 183 ARDLAPIGIRVMTIAPGLFGTPL 205
>U73514-1|AAB68958.1| 261|Homo sapiens short-chain alcohol
dehydrogenase protein.
Length = 261
Score = 48.0 bits (109), Expect = 3e-05
Identities = 36/143 (25%), Positives = 64/143 (44%), Gaps = 13/143 (9%)
Frame = +2
Query: 233 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 394
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 395 RSIYYLTMLAVPHLLESK----GXXXXXXXXXGIRSFPGVL---AYNISKASVDQFTRCV 553
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182
Query: 554 ALXLAPKGVRVNCVNPXVILTEL 622
A LAP G+RV + P + T L
Sbjct: 183 ARDLAPIGIRVMTIAPGLFGTPL 205
>L40802-1|AAC41917.1| 387|Homo sapiens 17-hydroxysteroid
dehydrogenase protein.
Length = 387
Score = 48.0 bits (109), Expect = 3e-05
Identities = 43/172 (25%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Frame = +2
Query: 125 FLSKLGAQL--SLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKT---IDH 289
+L +LG + + N +++ + C S L + D+TK I+ K +
Sbjct: 101 YLDELGFTVFAGVLNENGPGAEELRRTCSPRLSVLQM--DITKPVQIKDAYSKVAAMLQD 158
Query: 290 YGKLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXX 466
G L ++NNAG++ T E + Y + M N +T +P L +SKG
Sbjct: 159 RG-LWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNV 217
Query: 467 XXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTEL 622
G + +Y SKA+V F+ + L L+ G++V + P LT +
Sbjct: 218 SSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTNI 269
>L11708-1|AAA03562.1| 387|Homo sapiens 17 beta hydroxysteroid
dehydrogenase type 2 protein.
Length = 387
Score = 48.0 bits (109), Expect = 3e-05
Identities = 43/172 (25%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Frame = +2
Query: 125 FLSKLGAQL--SLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKT---IDH 289
+L +LG + + N +++ + C S L + D+TK I+ K +
Sbjct: 101 YLDELGFTVFAGVLNENGPGAEELRRTCSPRLSVLQM--DITKPVQIKDAYSKVAAMLQD 158
Query: 290 YGKLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXX 466
G L ++NNAG++ T E + Y + M N +T +P L +SKG
Sbjct: 159 RG-LWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNV 217
Query: 467 XXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTEL 622
G + +Y SKA+V F+ + L L+ G++V + P LT +
Sbjct: 218 SSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTNI 269
>CR456723-1|CAG33004.1| 261|Homo sapiens HADH2 protein.
Length = 261
Score = 48.0 bits (109), Expect = 3e-05
Identities = 36/143 (25%), Positives = 64/143 (44%), Gaps = 13/143 (9%)
Frame = +2
Query: 233 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 394
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 395 RSIYYLTMLAVPHLLESK----GXXXXXXXXXGIRSFPGVL---AYNISKASVDQFTRCV 553
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182
Query: 554 ALXLAPKGVRVNCVNPXVILTEL 622
A LAP G+RV + P + T L
Sbjct: 183 ARDLAPIGIRVMTIAPGLFGTPL 205
>BC059170-1|AAH59170.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 48.0 bits (109), Expect = 3e-05
Identities = 43/172 (25%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Frame = +2
Query: 125 FLSKLGAQL--SLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKT---IDH 289
+L +LG + + N +++ + C S L + D+TK I+ K +
Sbjct: 101 YLDELGFTVFAGVLNENGPGAEELRRTCSPRLSVLQM--DITKPVQIKDAYSKVAAMLQD 158
Query: 290 YGKLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXX 466
G L ++NNAG++ T E + Y + M N +T +P L +SKG
Sbjct: 159 RG-LWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNV 217
Query: 467 XXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTEL 622
G + +Y SKA+V F+ + L L+ G++V + P LT +
Sbjct: 218 SSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTNI 269
>BC009581-1|AAH09581.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 48.0 bits (109), Expect = 3e-05
Identities = 43/172 (25%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Frame = +2
Query: 125 FLSKLGAQL--SLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKT---IDH 289
+L +LG + + N +++ + C S L + D+TK I+ K +
Sbjct: 101 YLDELGFTVFAGVLNENGPGAEELRRTCSPRLSVLQM--DITKPVQIKDAYSKVAAMLQD 158
Query: 290 YGKLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXX 466
G L ++NNAG++ T E + Y + M N +T +P L +SKG
Sbjct: 159 RG-LWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNV 217
Query: 467 XXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTEL 622
G + +Y SKA+V F+ + L L+ G++V + P LT +
Sbjct: 218 SSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTNI 269
>BC000372-1|AAH00372.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 261
Score = 48.0 bits (109), Expect = 3e-05
Identities = 36/143 (25%), Positives = 64/143 (44%), Gaps = 13/143 (9%)
Frame = +2
Query: 233 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 394
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 395 RSIYYLTMLAVPHLLESK----GXXXXXXXXXGIRSFPGVL---AYNISKASVDQFTRCV 553
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182
Query: 554 ALXLAPKGVRVNCVNPXVILTEL 622
A LAP G+RV + P + T L
Sbjct: 183 ARDLAPIGIRVMTIAPGLFGTPL 205
>AY325910-1|AAP78485.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 48.0 bits (109), Expect = 3e-05
Identities = 43/172 (25%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Frame = +2
Query: 125 FLSKLGAQL--SLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKT---IDH 289
+L +LG + + N +++ + C S L + D+TK I+ K +
Sbjct: 101 YLDELGFTVFAGVLNENGPGAEELRRTCSPRLSVLQM--DITKPVQIKDAYSKVAAMLQD 158
Query: 290 YGKLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXX 466
G L ++NNAG++ T E + Y + M N +T +P L +SKG
Sbjct: 159 RG-LWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNV 217
Query: 467 XXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTEL 622
G + +Y SKA+V F+ + L L+ G++V + P LT +
Sbjct: 218 SSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTNI 269
>AY092415-1|AAM18189.1| 196|Homo sapiens endoplasmic
reticulum-associated amyloid beta peptide-binding
protein protein.
Length = 196
Score = 48.0 bits (109), Expect = 3e-05
Identities = 36/143 (25%), Positives = 64/143 (44%), Gaps = 13/143 (9%)
Frame = +2
Query: 233 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 394
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 13 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 72
Query: 395 RSIYYLTMLAVPHLLESK----GXXXXXXXXXGIRSFPGVL---AYNISKASVDQFTRCV 553
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 73 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 132
Query: 554 ALXLAPKGVRVNCVNPXVILTEL 622
A LAP G+RV + P + T L
Sbjct: 133 ARDLAPIGIRVMTIAPGLFGTPL 155
>AK223001-1|BAD96721.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 variant protein.
Length = 387
Score = 48.0 bits (109), Expect = 3e-05
Identities = 43/172 (25%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Frame = +2
Query: 125 FLSKLGAQL--SLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKT---IDH 289
+L +LG + + N +++ + C S L + D+TK I+ K +
Sbjct: 101 YLDELGFTVFAGVLNENGPGAEELRRTCSPRLSVLQM--DITKPVQIKDAYSKVAAMLQD 158
Query: 290 YGKLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXX 466
G L ++NNAG++ T E + Y + M N +T +P L +SKG
Sbjct: 159 RG-LWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNV 217
Query: 467 XXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTEL 622
G + +Y SKA+V F+ + L L+ G++V + P LT +
Sbjct: 218 SSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTNI 269
>AF069134-1|AAC39900.1| 261|Homo sapiens putative short-chain type
dehydrogenase/reductase protein.
Length = 261
Score = 48.0 bits (109), Expect = 3e-05
Identities = 36/143 (25%), Positives = 64/143 (44%), Gaps = 13/143 (9%)
Frame = +2
Query: 233 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 394
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 395 RSIYYLTMLAVPHLLESK----GXXXXXXXXXGIRSFPGVL---AYNISKASVDQFTRCV 553
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182
Query: 554 ALXLAPKGVRVNCVNPXVILTEL 622
A LAP G+RV + P + T L
Sbjct: 183 ARDLAPIGIRVMTIAPGLFGTPL 205
>AF037438-1|AAC16419.1| 261|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 10/short chain L-3-hydroxyacyl-CoA
deh protein.
Length = 261
Score = 48.0 bits (109), Expect = 3e-05
Identities = 36/143 (25%), Positives = 64/143 (44%), Gaps = 13/143 (9%)
Frame = +2
Query: 233 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 394
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 395 RSIYYLTMLAVPHLLESK----GXXXXXXXXXGIRSFPGVL---AYNISKASVDQFTRCV 553
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182
Query: 554 ALXLAPKGVRVNCVNPXVILTEL 622
A LAP G+RV + P + T L
Sbjct: 183 ARDLAPIGIRVMTIAPGLFGTPL 205
>AF035555-1|AAC15902.1| 261|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 10/short chain L-3-hydroxyacyl-CoA
deh protein.
Length = 261
Score = 48.0 bits (109), Expect = 3e-05
Identities = 36/143 (25%), Positives = 64/143 (44%), Gaps = 13/143 (9%)
Frame = +2
Query: 233 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 394
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 395 RSIYYLTMLAVPHLLESK----GXXXXXXXXXGIRSFPGVL---AYNISKASVDQFTRCV 553
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182
Query: 554 ALXLAPKGVRVNCVNPXVILTEL 622
A LAP G+RV + P + T L
Sbjct: 183 ARDLAPIGIRVMTIAPGLFGTPL 205
>X82460-1|CAA57843.1| 178|Homo sapiens 15-hydroxy prostaglandin
dehydrogenase protein.
Length = 178
Score = 47.2 bits (107), Expect = 5e-05
Identities = 30/103 (29%), Positives = 48/103 (46%), Gaps = 3/103 (2%)
Frame = +2
Query: 56 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVE-NLQKVSKDCDKFA--STLS 226
M+ GKV L GA+++L N+E +Q + ++F TL
Sbjct: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60
Query: 227 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT 355
I D+ + + +K +DH+G+LD+LVNNAG+ E T
Sbjct: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNKKNWEKT 103
>U63296-1|AAB53034.1| 143|Homo sapiens 15-hydroxyprostaglandin
dehydrogenase protein.
Length = 143
Score = 47.2 bits (107), Expect = 5e-05
Identities = 30/103 (29%), Positives = 48/103 (46%), Gaps = 3/103 (2%)
Frame = +2
Query: 56 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVE-NLQKVSKDCDKFA--STLS 226
M+ GKV L GA+++L N+E +Q + ++F TL
Sbjct: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60
Query: 227 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT 355
I D+ + + +K +DH+G+LD+LVNNAG+ E T
Sbjct: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKT 103
>AF229845-1|AAF63160.1| 311|Homo sapiens photoreceptor outer
segment all-trans retinol dehydrogenase protein.
Length = 311
Score = 46.8 bits (106), Expect = 6e-05
Identities = 30/110 (27%), Positives = 51/110 (46%), Gaps = 1/110 (0%)
Frame = +2
Query: 293 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXX 469
G++DVLVNNAG+ G +E SLA + +TN L +P + + G
Sbjct: 82 GEVDVLVNNAGMGLVGPLEGLSLAAMQNVFDTNFFGAVRLVKAVLPGMKRRRQGHIVVIS 141
Query: 470 XXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTE 619
G++ Y SK +++ F +A+ L + ++ V P ++TE
Sbjct: 142 SVMGLQGVIFNDVYAASKFALEGFFESLAIQLLQFNIFISLVEPGPVVTE 191
>BC002730-1|AAH02730.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 44.8 bits (101), Expect = 3e-04
Identities = 35/169 (20%), Positives = 70/169 (41%), Gaps = 3/169 (1%)
Frame = +2
Query: 125 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS-ITADLTKESDIEKIIKKTIDHYGKL 301
F + ++ L GR + L++ +++ + + D+ ++ + K + G +
Sbjct: 58 FAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVYQTAKAVREKVGDI 117
Query: 302 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXX 478
+LVNNA ++ ++ ++ + + N ++ T +P +LE G
Sbjct: 118 TILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKAFLPRMLELQNGHIVCLNSVL 177
Query: 479 GIRSFPGVLAYNISKASVDQFTRCVALXLAP-KGVRVNCVNPXVILTEL 622
+ + PG + Y SKAS F + L L GV V P TE+
Sbjct: 178 ALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTVLPFHTSTEM 226
>AL645761-1|CAI14999.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 44.8 bits (101), Expect = 3e-04
Identities = 35/169 (20%), Positives = 70/169 (41%), Gaps = 3/169 (1%)
Frame = +2
Query: 125 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS-ITADLTKESDIEKIIKKTIDHYGKL 301
F + ++ L GR + L++ +++ + + D+ ++ + K + G +
Sbjct: 58 FAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVYQTAKAVREKVGDI 117
Query: 302 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXX 478
+LVNNA ++ ++ ++ + + N ++ T +P +LE G
Sbjct: 118 TILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKAFLPRMLELQNGHIVCLNSVL 177
Query: 479 GIRSFPGVLAYNISKASVDQFTRCVALXLAP-KGVRVNCVNPXVILTEL 622
+ + PG + Y SKAS F + L L GV V P TE+
Sbjct: 178 ALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTVLPFHTSTEM 226
>AL513016-1|CAH74172.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 44.8 bits (101), Expect = 3e-04
Identities = 35/169 (20%), Positives = 70/169 (41%), Gaps = 3/169 (1%)
Frame = +2
Query: 125 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS-ITADLTKESDIEKIIKKTIDHYGKL 301
F + ++ L GR + L++ +++ + + D+ ++ + K + G +
Sbjct: 58 FAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVYQTAKAVREKVGDI 117
Query: 302 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXX 478
+LVNNA ++ ++ ++ + + N ++ T +P +LE G
Sbjct: 118 TILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKAFLPRMLELQNGHIVCLNSVL 177
Query: 479 GIRSFPGVLAYNISKASVDQFTRCVALXLAP-KGVRVNCVNPXVILTEL 622
+ + PG + Y SKAS F + L L GV V P TE+
Sbjct: 178 ALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTVLPFHTSTEM 226
>AK222593-1|BAD96313.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 variant protein.
Length = 302
Score = 44.8 bits (101), Expect = 3e-04
Identities = 35/169 (20%), Positives = 70/169 (41%), Gaps = 3/169 (1%)
Frame = +2
Query: 125 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS-ITADLTKESDIEKIIKKTIDHYGKL 301
F + ++ L GR + L++ +++ + + D+ ++ + K + G +
Sbjct: 58 FAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVYQTAKAVREKVGDI 117
Query: 302 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXX 478
+LVNNA ++ ++ ++ + + N ++ T +P +LE G
Sbjct: 118 TILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKAFLPRMLELQNGHIVCLNSVL 177
Query: 479 GIRSFPGVLAYNISKASVDQFTRCVALXLAP-KGVRVNCVNPXVILTEL 622
+ + PG + Y SKAS F + L L GV V P TE+
Sbjct: 178 ALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTVLPFHTSTEM 226
>AF179237-1|AAD55402.1| 302|Homo sapiens short-chain
dehydrogenase/reductase 1 protein.
Length = 302
Score = 44.8 bits (101), Expect = 3e-04
Identities = 35/169 (20%), Positives = 70/169 (41%), Gaps = 3/169 (1%)
Frame = +2
Query: 125 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS-ITADLTKESDIEKIIKKTIDHYGKL 301
F + ++ L GR + L++ +++ + + D+ ++ + K + G +
Sbjct: 58 FAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVYQTAKAVREKVGDI 117
Query: 302 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXX 478
+LVNNA ++ ++ ++ + + N ++ T +P +LE G
Sbjct: 118 TILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKAFLPRMLELQNGHIVCLNSVL 177
Query: 479 GIRSFPGVLAYNISKASVDQFTRCVALXLAP-KGVRVNCVNPXVILTEL 622
+ + PG + Y SKAS F + L L GV V P TE+
Sbjct: 178 ALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTVLPFHTSTEM 226
>AF061741-1|AAC63263.1| 302|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR1 protein.
Length = 302
Score = 44.8 bits (101), Expect = 3e-04
Identities = 35/169 (20%), Positives = 70/169 (41%), Gaps = 3/169 (1%)
Frame = +2
Query: 125 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS-ITADLTKESDIEKIIKKTIDHYGKL 301
F + ++ L GR + L++ +++ + + D+ ++ + K + G +
Sbjct: 58 FAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVYQTAKAVREKVGDI 117
Query: 302 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXX 478
+LVNNA ++ ++ ++ + + N ++ T +P +LE G
Sbjct: 118 TILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKAFLPRMLELQNGHIVCLNSVL 177
Query: 479 GIRSFPGVLAYNISKASVDQFTRCVALXLAP-KGVRVNCVNPXVILTEL 622
+ + PG + Y SKAS F + L L GV V P TE+
Sbjct: 178 ALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTVLPFHTSTEM 226
>DQ088988-1|AAZ85982.1| 118|Homo sapiens DHRS4L2 isoform 2 protein.
Length = 118
Score = 44.0 bits (99), Expect = 4e-04
Identities = 22/78 (28%), Positives = 40/78 (51%), Gaps = 1/78 (1%)
Frame = +2
Query: 368 YDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRS-FPGVLAYNISKASVDQFT 544
+D+ ++ NV++ +T VP + + G S PG YN+SK ++
Sbjct: 10 WDKTLDINVKAPALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLN 69
Query: 545 RCVALXLAPKGVRVNCVN 598
+A+ LAP+ +RVNC++
Sbjct: 70 NTLAIELAPRNIRVNCLH 87
>BC067131-1|AAH67131.1| 341|Homo sapiens retinol dehydrogenase 10
(all-trans) protein.
Length = 341
Score = 44.0 bits (99), Expect = 4e-04
Identities = 35/133 (26%), Positives = 59/133 (44%), Gaps = 4/133 (3%)
Frame = +2
Query: 230 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYY 409
T D+ K ++ ++ G++ VLVNNAG++ + +R M N + ++
Sbjct: 116 TCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFW 175
Query: 410 LTMLAVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVA--LXLAPK-G 577
T +P +LE + G G+ S GV Y SK V F ++ L A K G
Sbjct: 176 TTKAFLPTMLEINHGHIVTVASSLGLFSTAGVEDYCASKFGVVGFHESLSHELKAAEKDG 235
Query: 578 VRVNCVNPXVILT 616
++ V P ++ T
Sbjct: 236 IKTTLVCPYLVDT 248
>AY358270-1|AAQ88637.1| 341|Homo sapiens RDH10 protein.
Length = 341
Score = 44.0 bits (99), Expect = 4e-04
Identities = 35/133 (26%), Positives = 59/133 (44%), Gaps = 4/133 (3%)
Frame = +2
Query: 230 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYY 409
T D+ K ++ ++ G++ VLVNNAG++ + +R M N + ++
Sbjct: 116 TCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFW 175
Query: 410 LTMLAVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVA--LXLAPK-G 577
T +P +LE + G G+ S GV Y SK V F ++ L A K G
Sbjct: 176 TTKAFLPTMLEINHGHIVTVASSLGLFSTAGVEDYCASKFGVVGFHESLSHELKAAEKDG 235
Query: 578 VRVNCVNPXVILT 616
++ V P ++ T
Sbjct: 236 IKTTLVCPYLVDT 248
>AF456765-1|AAN64747.1| 341|Homo sapiens retinol dehydrogenase 10
protein.
Length = 341
Score = 44.0 bits (99), Expect = 4e-04
Identities = 35/133 (26%), Positives = 59/133 (44%), Gaps = 4/133 (3%)
Frame = +2
Query: 230 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYY 409
T D+ K ++ ++ G++ VLVNNAG++ + +R M N + ++
Sbjct: 116 TCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFW 175
Query: 410 LTMLAVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVA--LXLAPK-G 577
T +P +LE + G G+ S GV Y SK V F ++ L A K G
Sbjct: 176 TTKAFLPTMLEINHGHIVTVASSLGLFSTAGVEDYCASKFGVVGFHESLSHELKAAEKDG 235
Query: 578 VRVNCVNPXVILT 616
++ V P ++ T
Sbjct: 236 IKTTLVCPYLVDT 248
>U43559-1|AAC50725.1| 318|Homo sapiens 11-cis retinol dehydrogenase
protein.
Length = 318
Score = 42.3 bits (95), Expect = 0.001
Identities = 39/155 (25%), Positives = 67/155 (43%), Gaps = 1/155 (0%)
Frame = +2
Query: 155 LTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE 334
LT E+LQ+V+ + +TL D K ++ + G L LVNNAG+
Sbjct: 60 LTPSGAEDLQRVASS--RLHTTLLDITDPQSVQQAAKWVEMHVKEAG-LFGLVNNAGVAG 116
Query: 335 T-GTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAY 511
G + + R++N N +T+ +P L +++G G + G Y
Sbjct: 117 IIGPTPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAANGG-GY 175
Query: 512 NISKASVDQFTRCVALXLAPKGVRVNCVNPXVILT 616
+SK ++ F+ + +A G+RV+ V P T
Sbjct: 176 CVSKFGLEAFSDSLRRDVAHFGIRVSIVEPGFFRT 210
>BC028298-1|AAH28298.1| 318|Homo sapiens retinol dehydrogenase 5
(11-cis/9-cis) protein.
Length = 318
Score = 42.3 bits (95), Expect = 0.001
Identities = 39/155 (25%), Positives = 67/155 (43%), Gaps = 1/155 (0%)
Frame = +2
Query: 155 LTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE 334
LT E+LQ+V+ + +TL D K ++ + G L LVNNAG+
Sbjct: 60 LTPSGAEDLQRVASS--RLHTTLLDITDPQSVQQAAKWVEMHVKEAG-LFGLVNNAGVAG 116
Query: 335 T-GTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAY 511
G + + R++N N +T+ +P L +++G G + G Y
Sbjct: 117 IIGPTPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAANGG-GY 175
Query: 512 NISKASVDQFTRCVALXLAPKGVRVNCVNPXVILT 616
+SK ++ F+ + +A G+RV+ V P T
Sbjct: 176 CVSKFGLEAFSDSLRRDVAHFGIRVSIVEPGFFRT 210
>AL645761-2|CAI15000.1| 147|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 147
Score = 42.3 bits (95), Expect = 0.001
Identities = 30/131 (22%), Positives = 54/131 (41%), Gaps = 2/131 (1%)
Frame = +2
Query: 236 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 415
D+ ++ + K + G + +LVNNA ++ ++ ++ + + N ++ T
Sbjct: 11 DVGNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTT 70
Query: 416 MLAVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAP-KGVRVN 589
+P +LE G + + PG + Y SKAS F + L L GV
Sbjct: 71 KAFLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSAT 130
Query: 590 CVNPXVILTEL 622
V P TE+
Sbjct: 131 TVLPFHTSTEM 141
>AF037062-1|AAC09250.1| 318|Homo sapiens retinol dehydrogenase
protein.
Length = 318
Score = 42.3 bits (95), Expect = 0.001
Identities = 39/155 (25%), Positives = 67/155 (43%), Gaps = 1/155 (0%)
Frame = +2
Query: 155 LTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE 334
LT E+LQ+V+ + +TL D K ++ + G L LVNNAG+
Sbjct: 60 LTPSGAEDLQRVASS--RLHTTLLDITDPQSVQQAAKWVEMHVKEAG-LFGLVNNAGVAG 116
Query: 335 T-GTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAY 511
G + + R++N N +T+ +P L +++G G + G Y
Sbjct: 117 IIGPTPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAANGG-GY 175
Query: 512 NISKASVDQFTRCVALXLAPKGVRVNCVNPXVILT 616
+SK ++ F+ + +A G+RV+ V P T
Sbjct: 176 CVSKFGLEAFSDSLRRDVAHFGIRVSIVEPGFFRT 210
>AY358473-1|AAQ88837.1| 331|Homo sapiens RDH13 protein.
Length = 331
Score = 41.9 bits (94), Expect = 0.002
Identities = 45/200 (22%), Positives = 78/200 (39%), Gaps = 15/200 (7%)
Frame = +2
Query: 68 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA---D 238
GK V L++ G + L R++E + +KD + A D
Sbjct: 38 GKTVIVTGANTGIGKQTALELARRGGNIILACRDMEKCEAAAKDIRGETLNHHVNARHLD 97
Query: 239 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIET--GTIENTSLAQY----------DRLM 382
L I + K I+ ++D+L+NNAG++ T E+ Q+ L+
Sbjct: 98 LASLKSIREFAAKIIEEEERVDILINNAGVMRCPHWTTEDGFEMQFGVNHLGHFLLTNLL 157
Query: 383 NTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALX 562
+++ ++ + L G R + AY SK ++ FT+ ++
Sbjct: 158 LDKLKASAPSRIINLSSLAHVAGHIDFDDLNWQTRKYNTKAAYCQSKLAIVLFTKELSRR 217
Query: 563 LAPKGVRVNCVNPXVILTEL 622
L GV VN ++P V TEL
Sbjct: 218 LQGSGVTVNALHPGVARTEL 237
>BC020710-1|AAH20710.1| 317|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 6 homolog (mouse) protein.
Length = 317
Score = 41.5 bits (93), Expect = 0.002
Identities = 33/134 (24%), Positives = 61/134 (45%), Gaps = 3/134 (2%)
Frame = +2
Query: 224 SITADLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIETGTI-ENTSLAQYDRLMNTNV 394
++T D+TK I + +H G + LVNNAGI+ T+ E + ++ N+
Sbjct: 79 TVTLDVTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPITLCEWLNTEDSMNMLKVNL 138
Query: 395 RSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPK 574
+ +T+ +P + ++G G +F V Y +SK V+ F+ + +
Sbjct: 139 IGVIQVTLSMLPLVRRARGRIVNVSSILGRVAF-FVGGYCVSKYGVEAFSDILRREIQHF 197
Query: 575 GVRVNCVNPXVILT 616
GV+++ V P T
Sbjct: 198 GVKISIVEPGYFRT 211
>AF223225-1|AAF81017.1| 317|Homo sapiens 3-hydroxysteroid epimerase
protein.
Length = 317
Score = 41.5 bits (93), Expect = 0.002
Identities = 33/134 (24%), Positives = 61/134 (45%), Gaps = 3/134 (2%)
Frame = +2
Query: 224 SITADLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIETGTI-ENTSLAQYDRLMNTNV 394
++T D+TK I + +H G + LVNNAGI+ T+ E + ++ N+
Sbjct: 79 TVTLDVTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPITLCEWLNTEDSMNMLKVNL 138
Query: 395 RSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPK 574
+ +T+ +P + ++G G +F V Y +SK V+ F+ + +
Sbjct: 139 IGVIQVTLSMLPLVRRARGRIVNVSSILGRVAF-FVGGYCVSKYGVEAFSDILRREIQHF 197
Query: 575 GVRVNCVNPXVILT 616
GV+++ V P T
Sbjct: 198 GVKISIVEPGYFRT 211
>AF016509-1|AAB67236.1| 317|Homo sapiens oxidoreductase protein.
Length = 317
Score = 41.5 bits (93), Expect = 0.002
Identities = 33/134 (24%), Positives = 61/134 (45%), Gaps = 3/134 (2%)
Frame = +2
Query: 224 SITADLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIETGTI-ENTSLAQYDRLMNTNV 394
++T D+TK I + +H G + LVNNAGI+ T+ E + ++ N+
Sbjct: 79 TVTLDVTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPITLCEWLNTEDSMNMLKVNL 138
Query: 395 RSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPK 574
+ +T+ +P + ++G G +F V Y +SK V+ F+ + +
Sbjct: 139 IGVIQVTLSMLPLVRRARGRIVNVSSILGRVAF-FVGGYCVSKYGVEAFSDILRREIQHF 197
Query: 575 GVRVNCVNPXVILT 616
GV+++ V P T
Sbjct: 198 GVKISIVEPGYFRT 211
>AK075392-1|BAC11591.1| 331|Homo sapiens protein ( Homo sapiens
cDNA PSEC0082 fis, clone NT2RP2004966, highly similar to
Retinol dehydrogenase 13 (EC 1.1.1.-). ).
Length = 331
Score = 40.7 bits (91), Expect = 0.004
Identities = 45/200 (22%), Positives = 77/200 (38%), Gaps = 15/200 (7%)
Frame = +2
Query: 68 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA---D 238
GK V L++ G + L R++E + +KD + A D
Sbjct: 38 GKTVIVTGANTGIGKQTALELARRGGNIILACRDMEKCEAAAKDIRGETLNHHVNARHLD 97
Query: 239 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIET--GTIENTSLAQY----------DRLM 382
L I K I+ ++D+L+NNAG++ T E+ Q+ L+
Sbjct: 98 LASLKSIRVFAAKIIEEEERVDILINNAGVMRCPHWTTEDGFEMQFGVNHLGHFLLTNLL 157
Query: 383 NTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALX 562
+++ ++ + L G R + AY SK ++ FT+ ++
Sbjct: 158 LDKLKASAPSRIINLSSLAHVAGHIDFDDLNWQTRKYNTKAAYCQSKLAIVLFTKELSRR 217
Query: 563 LAPKGVRVNCVNPXVILTEL 622
L GV VN ++P V TEL
Sbjct: 218 LQGSGVTVNALHPGVARTEL 237
>U78302-1|AAB88724.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 40.3 bits (90), Expect = 0.005
Identities = 37/191 (19%), Positives = 74/191 (38%), Gaps = 4/191 (2%)
Frame = +2
Query: 59 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTL--SIT 232
+F GKV LS LGAQ + R ++ L+ ++ +I
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQ 115
Query: 233 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 412
D+ ++ + + I G ++++NNA E S + + + + ++
Sbjct: 116 CDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAFV 175
Query: 413 TMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNIS-KASVDQFTRCVALXLAPKGVRV 586
T+ L+++ KG + G + + S KA V+ ++ +A G+R
Sbjct: 176 TLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRF 235
Query: 587 NCVNPXVILTE 619
N + P I T+
Sbjct: 236 NVIQPGPIKTK 246
>U49352-1|AAB09423.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 40.3 bits (90), Expect = 0.005
Identities = 37/191 (19%), Positives = 74/191 (38%), Gaps = 4/191 (2%)
Frame = +2
Query: 59 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTL--SIT 232
+F GKV LS LGAQ + R ++ L+ ++ +I
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQ 115
Query: 233 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 412
D+ ++ + + I G ++++NNA E S + + + + ++
Sbjct: 116 CDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAFV 175
Query: 413 TMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNIS-KASVDQFTRCVALXLAPKGVRV 586
T+ L+++ KG + G + + S KA V+ ++ +A G+R
Sbjct: 176 TLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRF 235
Query: 587 NCVNPXVILTE 619
N + P I T+
Sbjct: 236 NVIQPGPIKTK 246
>L26050-1|AAA67551.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 40.3 bits (90), Expect = 0.005
Identities = 37/191 (19%), Positives = 74/191 (38%), Gaps = 4/191 (2%)
Frame = +2
Query: 59 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTL--SIT 232
+F GKV LS LGAQ + R ++ L+ ++ +I
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQ 115
Query: 233 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 412
D+ ++ + + I G ++++NNA E S + + + + ++
Sbjct: 116 CDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAFV 175
Query: 413 TMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNIS-KASVDQFTRCVALXLAPKGVRV 586
T+ L+++ KG + G + + S KA V+ ++ +A G+R
Sbjct: 176 TLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRF 235
Query: 587 NCVNPXVILTE 619
N + P I T+
Sbjct: 236 NVIQPGPIKTK 246
>BC105082-1|AAI05083.1| 335|Homo sapiens 2,4-dienoyl CoA reductase
1, mitochondrial protein.
Length = 335
Score = 40.3 bits (90), Expect = 0.005
Identities = 37/191 (19%), Positives = 74/191 (38%), Gaps = 4/191 (2%)
Frame = +2
Query: 59 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTL--SIT 232
+F GKV LS LGAQ + R ++ L+ ++ +I
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQ 115
Query: 233 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 412
D+ ++ + + I G ++++NNA E S + + + + ++
Sbjct: 116 CDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAFV 175
Query: 413 TMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNIS-KASVDQFTRCVALXLAPKGVRV 586
T+ L+++ KG + G + + S KA V+ ++ +A G+R
Sbjct: 176 TLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRF 235
Query: 587 NCVNPXVILTE 619
N + P I T+
Sbjct: 236 NVIQPGPIKTK 246
>BC105080-1|AAI05081.1| 335|Homo sapiens 2,4-dienoyl CoA reductase
1, mitochondrial protein.
Length = 335
Score = 40.3 bits (90), Expect = 0.005
Identities = 37/191 (19%), Positives = 74/191 (38%), Gaps = 4/191 (2%)
Frame = +2
Query: 59 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTL--SIT 232
+F GKV LS LGAQ + R ++ L+ ++ +I
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQ 115
Query: 233 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 412
D+ ++ + + I G ++++NNA E S + + + + ++
Sbjct: 116 CDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAFV 175
Query: 413 TMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNIS-KASVDQFTRCVALXLAPKGVRV 586
T+ L+++ KG + G + + S KA V+ ++ +A G+R
Sbjct: 176 TLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRF 235
Query: 587 NCVNPXVILTE 619
N + P I T+
Sbjct: 236 NVIQPGPIKTK 246
>AC004612-1|AAC14671.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
precursor protein.
Length = 335
Score = 40.3 bits (90), Expect = 0.005
Identities = 37/191 (19%), Positives = 74/191 (38%), Gaps = 4/191 (2%)
Frame = +2
Query: 59 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTL--SIT 232
+F GKV LS LGAQ + R ++ L+ ++ +I
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQ 115
Query: 233 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 412
D+ ++ + + I G ++++NNA E S + + + + ++
Sbjct: 116 CDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAFV 175
Query: 413 TMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNIS-KASVDQFTRCVALXLAPKGVRV 586
T+ L+++ KG + G + + S KA V+ ++ +A G+R
Sbjct: 176 TLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRF 235
Query: 587 NCVNPXVILTE 619
N + P I T+
Sbjct: 236 NVIQPGPIKTK 246
>Z97054-7|CAI42652.1| 252|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 252
Score = 39.9 bits (89), Expect = 0.007
Identities = 31/129 (24%), Positives = 57/129 (44%), Gaps = 13/129 (10%)
Frame = +2
Query: 233 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 394
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 395 RSIYYLTMLAVPHLLESK----GXXXXXXXXXGIRSFPGVL---AYNISKASVDQFTRCV 553
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182
Query: 554 ALXLAPKGV 580
A LAP G+
Sbjct: 183 ARDLAPIGL 191
>U89281-1|AAB88252.1| 317|Homo sapiens oxidative 3 alpha
hydroxysteroid dehydrogenase protein.
Length = 317
Score = 39.9 bits (89), Expect = 0.007
Identities = 33/134 (24%), Positives = 60/134 (44%), Gaps = 3/134 (2%)
Frame = +2
Query: 224 SITADLTKESDIEKIIKKTIDHYG--KLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNV 394
++T D+TK I + +H G +L LVNNAGI+ T+ E + ++ N+
Sbjct: 79 TVTLDVTKMESIAAATQWVKEHVGDRRLWGLVNNAGILTPITLCEWLNTEDSMNMLKVNL 138
Query: 395 RSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPK 574
+ +T+ +P + ++G G F Y +SK V+ F+ + +
Sbjct: 139 IGVIQVTLSMLPLVRRARGKNCQCLQHSGKSCFL-CRGYCVSKYGVEAFSDILRREIQHF 197
Query: 575 GVRVNCVNPXVILT 616
GV+++ V P T
Sbjct: 198 GVKISIVEPGYFRT 211
>BC064525-1|AAH64525.1| 309|Homo sapiens epidermal retinal
dehydrogenase 2 protein.
Length = 309
Score = 39.9 bits (89), Expect = 0.007
Identities = 37/192 (19%), Positives = 73/192 (38%), Gaps = 6/192 (3%)
Frame = +2
Query: 59 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTL--SIT 232
N AG++V ++LG+ L L N E ++ K + +T + T
Sbjct: 37 NVAGEIVLITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREAGATRVHAYT 96
Query: 233 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 412
D +++ + ++ + G + +L+NNAGI+ + ++ + N ++ +
Sbjct: 97 CDCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLWT 156
Query: 413 TMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCV---ALXLAPKGV 580
+P ++ G G+ G+ Y SK + F V KG+
Sbjct: 157 YKAFLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQKGI 216
Query: 581 RVNCVNPXVILT 616
+ V P I T
Sbjct: 217 KTTIVCPFFIKT 228
>BC037219-1|AAH37219.2| 309|Homo sapiens epidermal retinal
dehydrogenase 2 protein.
Length = 309
Score = 39.9 bits (89), Expect = 0.007
Identities = 37/192 (19%), Positives = 73/192 (38%), Gaps = 6/192 (3%)
Frame = +2
Query: 59 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTL--SIT 232
N AG++V ++LG+ L L N E ++ K + +T + T
Sbjct: 37 NVAGEIVLITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREAGATRVHAYT 96
Query: 233 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 412
D +++ + ++ + G + +L+NNAGI+ + ++ + N ++ +
Sbjct: 97 CDCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLWT 156
Query: 413 TMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCV---ALXLAPKGV 580
+P ++ G G+ G+ Y SK + F V KG+
Sbjct: 157 YKAFLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQKGI 216
Query: 581 RVNCVNPXVILT 616
+ V P I T
Sbjct: 217 KTTIVCPFFIKT 228
>BC008708-1|AAH08708.1| 252|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 252
Score = 39.9 bits (89), Expect = 0.007
Identities = 31/129 (24%), Positives = 57/129 (44%), Gaps = 13/129 (10%)
Frame = +2
Query: 233 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 394
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 395 RSIYYLTMLAVPHLLESK----GXXXXXXXXXGIRSFPGVL---AYNISKASVDQFTRCV 553
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182
Query: 554 ALXLAPKGV 580
A LAP G+
Sbjct: 183 ARDLAPIGL 191
>AB083038-1|BAB91014.1| 309|Homo sapiens retinal short chain
dehydrogenase reductase protein.
Length = 309
Score = 39.9 bits (89), Expect = 0.007
Identities = 37/192 (19%), Positives = 73/192 (38%), Gaps = 6/192 (3%)
Frame = +2
Query: 59 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTL--SIT 232
N AG++V ++LG+ L L N E ++ K + +T + T
Sbjct: 37 NVAGEIVLITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREAGATRVRAYT 96
Query: 233 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 412
D +++ + ++ + G + +L+NNAGI+ + ++ + N ++ +
Sbjct: 97 CDCSQKEGVYRVADQVKKEIGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLWT 156
Query: 413 TMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCV---ALXLAPKGV 580
+P ++ G G+ G+ Y SK + F V KG+
Sbjct: 157 YKAFLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQKGI 216
Query: 581 RVNCVNPXVILT 616
+ V P I T
Sbjct: 217 KTTIVCPFFIKT 228
>BT007239-1|AAP35903.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 39.5 bits (88), Expect = 0.009
Identities = 29/108 (26%), Positives = 48/108 (44%), Gaps = 2/108 (1%)
Frame = +2
Query: 305 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXX 478
V+V+ AGI + + + S +D+++ N++ + +T A L+ + +G
Sbjct: 99 VVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIV 158
Query: 479 GIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTEL 622
G G Y SKA V T+ A L G+R N V P I T +
Sbjct: 159 GKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPM 206
>BC008185-1|AAH08185.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 39.5 bits (88), Expect = 0.009
Identities = 29/108 (26%), Positives = 48/108 (44%), Gaps = 2/108 (1%)
Frame = +2
Query: 305 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXX 478
V+V+ AGI + + + S +D+++ N++ + +T A L+ + +G
Sbjct: 99 VVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIV 158
Query: 479 GIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTEL 622
G G Y SKA V T+ A L G+R N V P I T +
Sbjct: 159 GKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPM 206
>AL844527-12|CAI41840.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 39.5 bits (88), Expect = 0.009
Identities = 29/108 (26%), Positives = 48/108 (44%), Gaps = 2/108 (1%)
Frame = +2
Query: 305 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXX 478
V+V+ AGI + + + S +D+++ N++ + +T A L+ + +G
Sbjct: 99 VVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIV 158
Query: 479 GIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTEL 622
G G Y SKA V T+ A L G+R N V P I T +
Sbjct: 159 GKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPM 206
>AL713971-6|CAI17657.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 39.5 bits (88), Expect = 0.009
Identities = 29/108 (26%), Positives = 48/108 (44%), Gaps = 2/108 (1%)
Frame = +2
Query: 305 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXX 478
V+V+ AGI + + + S +D+++ N++ + +T A L+ + +G
Sbjct: 99 VVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIV 158
Query: 479 GIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTEL 622
G G Y SKA V T+ A L G+R N V P I T +
Sbjct: 159 GKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPM 206
>AL662824-24|CAI17616.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 39.5 bits (88), Expect = 0.009
Identities = 29/108 (26%), Positives = 48/108 (44%), Gaps = 2/108 (1%)
Frame = +2
Query: 305 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXX 478
V+V+ AGI + + + S +D+++ N++ + +T A L+ + +G
Sbjct: 99 VVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIV 158
Query: 479 GIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTEL 622
G G Y SKA V T+ A L G+R N V P I T +
Sbjct: 159 GKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPM 206
>AL645940-10|CAI18068.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 39.5 bits (88), Expect = 0.009
Identities = 29/108 (26%), Positives = 48/108 (44%), Gaps = 2/108 (1%)
Frame = +2
Query: 305 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXX 478
V+V+ AGI + + + S +D+++ N++ + +T A L+ + +G
Sbjct: 99 VVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIV 158
Query: 479 GIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTEL 622
G G Y SKA V T+ A L G+R N V P I T +
Sbjct: 159 GKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPM 206
>AL031228-10|CAC38444.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 39.5 bits (88), Expect = 0.009
Identities = 29/108 (26%), Positives = 48/108 (44%), Gaps = 2/108 (1%)
Frame = +2
Query: 305 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXX 478
V+V+ AGI + + + S +D+++ N++ + +T A L+ + +G
Sbjct: 99 VVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIV 158
Query: 479 GIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTEL 622
G G Y SKA V T+ A L G+R N V P I T +
Sbjct: 159 GKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPM 206
>AF057034-1|AAC39922.1| 317|Homo sapiens sterol/retinol
dehydrogenase protein.
Length = 317
Score = 39.1 bits (87), Expect = 0.012
Identities = 35/135 (25%), Positives = 63/135 (46%), Gaps = 4/135 (2%)
Frame = +2
Query: 224 SITADLTKESDIEKI---IKKTIDHYGKLDVLVNNAGI-IETGTIENTSLAQYDRLMNTN 391
++T D+TK + +K+ + G L LVNNAGI + T E + + +++ N
Sbjct: 79 TVTLDVTKTESVAAAAQWVKECVRDKG-LWGLVNNAGISLPTAPNELLTKQDFVTILDVN 137
Query: 392 VRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAP 571
+ + +T+ +P + +++G G S G Y ISK V+ F+ + L+
Sbjct: 138 LLGVIDVTLSLLPLVRKARGRVVNVSSVMGRVSLFGG-GYCISKYGVEAFSDSLRRELSY 196
Query: 572 KGVRVNCVNPXVILT 616
GV+V + P T
Sbjct: 197 FGVKVAMIEPGYFKT 211
>U89717-1|AAB93668.1| 318|Homo sapiens 9-cis-retinol specific
dehydrogenase protein.
Length = 318
Score = 38.7 bits (86), Expect = 0.017
Identities = 39/155 (25%), Positives = 65/155 (41%), Gaps = 1/155 (0%)
Frame = +2
Query: 155 LTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE 334
LT E+LQ V+ F +TL D K ++ + G L LVNNAG+
Sbjct: 60 LTPSGAEDLQGVASS--GFNTTLLDITDPQSFQQAAKWVEMHVKEAG-LFGLVNNAGVAG 116
Query: 335 T-GTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAY 511
G + + R++N N +T+ +P L +++G G + G Y
Sbjct: 117 IIGPTPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAANGG-GY 175
Query: 512 NISKASVDQFTRCVALXLAPKGVRVNCVNPXVILT 616
+SK ++ F+ + +A G+R + V P T
Sbjct: 176 CVSKFGLEAFSDSLRRDVAHFGIRESIVEPGFFRT 210
>AK057667-1|BAB71545.1| 231|Homo sapiens protein ( Homo sapiens
cDNA FLJ33105 fis, clone TRACH2000926, weakly similar to
PROBABLE OXIDOREDUCTASE EPHD (EC 1.-.-.-). ).
Length = 231
Score = 37.9 bits (84), Expect = 0.029
Identities = 35/187 (18%), Positives = 71/187 (37%), Gaps = 6/187 (3%)
Frame = +2
Query: 59 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTL--SIT 232
N AG++V ++LG+ L L N E ++ K + +T + T
Sbjct: 37 NVAGEIVLITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREAGATRVHAYT 96
Query: 233 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 412
D +++ + ++ + G + +L+NNAGI+ + ++ + N ++ +
Sbjct: 97 CDCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLWT 156
Query: 413 TMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCV---ALXLAPKGV 580
+P ++ G G+ G+ Y SK + F V KG+
Sbjct: 157 YKAFLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQKGI 216
Query: 581 RVNCVNP 601
+ V P
Sbjct: 217 KTTIVCP 223
>AF086735-1|AAC72923.1| 317|Homo sapiens retinol dehydrogenase
protein.
Length = 317
Score = 37.9 bits (84), Expect = 0.029
Identities = 38/136 (27%), Positives = 62/136 (45%), Gaps = 5/136 (3%)
Frame = +2
Query: 224 SITADLTKESDIEKI---IKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRL--MNT 388
++T D+TK + +K+ + G L LVNNAGI T N L + D L ++
Sbjct: 79 TVTLDVTKTESVAAAAQWVKECVRDKG-LWGLVNNAGI-SLPTAPNELLTKQDLLTILDV 136
Query: 389 NVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLA 568
N+ + +T+ +P + ++G G S G Y ISK V+ F+ + L+
Sbjct: 137 NLLGVIDVTLNLLPLVRRARGRVVNVFSVMGRVSLFGG-GYCISKYGVEAFSDSLRRELS 195
Query: 569 PKGVRVNCVNPXVILT 616
GV+V + P T
Sbjct: 196 YFGVKVAMIEPGYFKT 211
>CR457180-1|CAG33461.1| 318|Homo sapiens RDH11 protein.
Length = 318
Score = 37.1 bits (82), Expect = 0.050
Identities = 48/206 (23%), Positives = 77/206 (37%), Gaps = 16/206 (7%)
Frame = +2
Query: 53 TMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSIT 232
T+ GKVV L++ GA++ L R+VE + V+K+ +
Sbjct: 36 TVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVL 95
Query: 233 A---DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 403
DL+ I K + L VL+NNAG++ + ++ + N
Sbjct: 96 VRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTAD--GFEMHIGVNHLGH 153
Query: 404 YYLTMLAVPHLLESKGXXXXXXXX-------------XGIRSFPGVLAYNISKASVDQFT 544
+ LT L + L ES G + + LAY SK + FT
Sbjct: 154 FLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFT 213
Query: 545 RCVALXLAPKGVRVNCVNPXVILTEL 622
+ +A L GV V+P + +EL
Sbjct: 214 QELARRLKGSGVTTYSVHPGTVQSEL 239
>BC037302-1|AAH37302.1| 318|Homo sapiens retinol dehydrogenase 11
(all-trans/9-cis/11-cis) protein.
Length = 318
Score = 37.1 bits (82), Expect = 0.050
Identities = 48/206 (23%), Positives = 77/206 (37%), Gaps = 16/206 (7%)
Frame = +2
Query: 53 TMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSIT 232
T+ GKVV L++ GA++ L R+VE + V+K+ +
Sbjct: 36 TVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVL 95
Query: 233 A---DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 403
DL+ I K + L VL+NNAG++ + ++ + N
Sbjct: 96 VRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTAD--GFEMHIGVNHLGH 153
Query: 404 YYLTMLAVPHLLESKGXXXXXXXX-------------XGIRSFPGVLAYNISKASVDQFT 544
+ LT L + L ES G + + LAY SK + FT
Sbjct: 154 FLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFT 213
Query: 545 RCVALXLAPKGVRVNCVNPXVILTEL 622
+ +A L GV V+P + +EL
Sbjct: 214 QELARRLKGSGVTTYSVHPGTVQSEL 239
>BC026274-1|AAH26274.1| 318|Homo sapiens retinol dehydrogenase 11
(all-trans/9-cis/11-cis) protein.
Length = 318
Score = 37.1 bits (82), Expect = 0.050
Identities = 48/206 (23%), Positives = 77/206 (37%), Gaps = 16/206 (7%)
Frame = +2
Query: 53 TMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSIT 232
T+ GKVV L++ GA++ L R+VE + V+K+ +
Sbjct: 36 TVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVL 95
Query: 233 A---DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 403
DL+ I K + L VL+NNAG++ + ++ + N
Sbjct: 96 VRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTAD--GFEMHIGVNHLGH 153
Query: 404 YYLTMLAVPHLLESKGXXXXXXXX-------------XGIRSFPGVLAYNISKASVDQFT 544
+ LT L + L ES G + + LAY SK + FT
Sbjct: 154 FLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFT 213
Query: 545 RCVALXLAPKGVRVNCVNPXVILTEL 622
+ +A L GV V+P + +EL
Sbjct: 214 QELARRLKGSGVTTYSVHPGTVQSEL 239
>BC011727-1|AAH11727.1| 318|Homo sapiens RDH11 protein protein.
Length = 318
Score = 37.1 bits (82), Expect = 0.050
Identities = 48/206 (23%), Positives = 77/206 (37%), Gaps = 16/206 (7%)
Frame = +2
Query: 53 TMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSIT 232
T+ GKVV L++ GA++ L R+VE + V+K+ +
Sbjct: 36 TVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVL 95
Query: 233 A---DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 403
DL+ I K + L VL+NNAG++ + ++ + N
Sbjct: 96 VRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTAD--GFEMHIGVNHLGH 153
Query: 404 YYLTMLAVPHLLESKGXXXXXXXX-------------XGIRSFPGVLAYNISKASVDQFT 544
+ LT L + L ES G + + LAY SK + FT
Sbjct: 154 FLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFT 213
Query: 545 RCVALXLAPKGVRVNCVNPXVILTEL 622
+ +A L GV V+P + +EL
Sbjct: 214 QELARRLKGSGVTTYSVHPGTVQSEL 239
>BC000112-1|AAH00112.1| 318|Homo sapiens retinol dehydrogenase 11
(all-trans/9-cis/11-cis) protein.
Length = 318
Score = 37.1 bits (82), Expect = 0.050
Identities = 48/206 (23%), Positives = 77/206 (37%), Gaps = 16/206 (7%)
Frame = +2
Query: 53 TMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSIT 232
T+ GKVV L++ GA++ L R+VE + V+K+ +
Sbjct: 36 TVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVL 95
Query: 233 A---DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 403
DL+ I K + L VL+NNAG++ + ++ + N
Sbjct: 96 VRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTAD--GFEMHIGVNHLGH 153
Query: 404 YYLTMLAVPHLLESKGXXXXXXXX-------------XGIRSFPGVLAYNISKASVDQFT 544
+ LT L + L ES G + + LAY SK + FT
Sbjct: 154 FLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFT 213
Query: 545 RCVALXLAPKGVRVNCVNPXVILTEL 622
+ +A L GV V+P + +EL
Sbjct: 214 QELARRLKGSGVTTYSVHPGTVQSEL 239
>AF395068-1|AAK72049.1| 318|Homo sapiens HCV core-binding protein
HCBP12 protein.
Length = 318
Score = 37.1 bits (82), Expect = 0.050
Identities = 48/206 (23%), Positives = 77/206 (37%), Gaps = 16/206 (7%)
Frame = +2
Query: 53 TMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSIT 232
T+ GKVV L++ GA++ L R+VE + V+K+ +
Sbjct: 36 TVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVL 95
Query: 233 A---DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 403
DL+ I K + L VL+NNAG++ + ++ + N
Sbjct: 96 VRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTAD--GFEMHIGVNHLGH 153
Query: 404 YYLTMLAVPHLLESKGXXXXXXXX-------------XGIRSFPGVLAYNISKASVDQFT 544
+ LT L + L ES G + + LAY SK + FT
Sbjct: 154 FLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFT 213
Query: 545 RCVALXLAPKGVRVNCVNPXVILTEL 622
+ +A L GV V+P + +EL
Sbjct: 214 QELARRLKGSGVTTYSVHPGTVQSEL 239
>AF167438-1|AAF89632.1| 318|Homo sapiens androgen-regulated
short-chain dehydrogenase/reductase 1 protein.
Length = 318
Score = 37.1 bits (82), Expect = 0.050
Identities = 48/206 (23%), Positives = 77/206 (37%), Gaps = 16/206 (7%)
Frame = +2
Query: 53 TMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSIT 232
T+ GKVV L++ GA++ L R+VE + V+K+ +
Sbjct: 36 TVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVL 95
Query: 233 A---DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 403
DL+ I K + L VL+NNAG++ + ++ + N
Sbjct: 96 VRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTAD--GFEMHIGVNHLGH 153
Query: 404 YYLTMLAVPHLLESKGXXXXXXXX-------------XGIRSFPGVLAYNISKASVDQFT 544
+ LT L + L ES G + + LAY SK + FT
Sbjct: 154 FLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFT 213
Query: 545 RCVALXLAPKGVRVNCVNPXVILTEL 622
+ +A L GV V+P + +EL
Sbjct: 214 QELARRLKGSGVTTYSVHPGTVQSEL 239
>AF151840-1|AAD34077.1| 318|Homo sapiens CGI-82 protein protein.
Length = 318
Score = 37.1 bits (82), Expect = 0.050
Identities = 48/206 (23%), Positives = 77/206 (37%), Gaps = 16/206 (7%)
Frame = +2
Query: 53 TMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSIT 232
T+ GKVV L++ GA++ L R+VE + V+K+ +
Sbjct: 36 TVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVL 95
Query: 233 A---DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 403
DL+ I K + L VL+NNAG++ + ++ + N
Sbjct: 96 VRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTAD--GFEMHIGVNHLGH 153
Query: 404 YYLTMLAVPHLLESKGXXXXXXXX-------------XGIRSFPGVLAYNISKASVDQFT 544
+ LT L + L ES G + + LAY SK + FT
Sbjct: 154 FLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFT 213
Query: 545 RCVALXLAPKGVRVNCVNPXVILTEL 622
+ +A L GV V+P + +EL
Sbjct: 214 QELARRLKGSGVTTYSVHPGTVQSEL 239
>AB209653-1|BAD92890.1| 166|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 isoform 2 variant protein.
Length = 166
Score = 36.7 bits (81), Expect = 0.067
Identities = 23/86 (26%), Positives = 47/86 (54%), Gaps = 2/86 (2%)
Frame = +2
Query: 128 LSKLGAQLSLTGRNVENLQK-VSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 304
L++ GA + ++ R +N+ + ++K + S I + K D E+++ K ++H G +D
Sbjct: 73 LARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEHCGGVD 132
Query: 305 VLVNNAGIIE-TGTIENTSLAQYDRL 379
LV +AG+ G+ TS +D++
Sbjct: 133 FLVCSAGVNPLVGSTLGTSEQIWDKV 158
>CR457356-1|CAG33637.1| 181|Homo sapiens MGC4172 protein.
Length = 181
Score = 36.3 bits (80), Expect = 0.088
Identities = 30/118 (25%), Positives = 52/118 (44%), Gaps = 7/118 (5%)
Frame = +2
Query: 287 HYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE---SKGXX 457
H G +D+ +NNAG+ T+ + S + + + N NV ++ T A + E G
Sbjct: 9 HSG-VDICINNAGLARPDTLLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNVDDGHI 67
Query: 458 XXXXXXXGIRSFPGVLA--YNISKASVDQFTRCVALXL--APKGVRVNCVNPXVILTE 619
G R P + Y+ +K +V T + L A +R C++P V+ T+
Sbjct: 68 ININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREAQTHIRATCISPGVVETQ 125
>AK026196-1|BAB15390.1| 181|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22543 fis, clone HSI00212. ).
Length = 181
Score = 36.3 bits (80), Expect = 0.088
Identities = 30/118 (25%), Positives = 52/118 (44%), Gaps = 7/118 (5%)
Frame = +2
Query: 287 HYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE---SKGXX 457
H G +D+ +NNAG+ T+ + S + + + N NV ++ T A + E G
Sbjct: 9 HSG-VDICINNAGLARPDTLLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNVDDGHI 67
Query: 458 XXXXXXXGIRSFPGVLA--YNISKASVDQFTRCVALXL--APKGVRVNCVNPXVILTE 619
G R P + Y+ +K +V T + L A +R C++P V+ T+
Sbjct: 68 ININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREAQTHIRATCISPGVVETQ 125
>BC009881-1|AAH09881.1| 260|Homo sapiens retinol dehydrogenase 13
(all-trans/9-cis) protein.
Length = 260
Score = 35.5 bits (78), Expect = 0.15
Identities = 34/141 (24%), Positives = 59/141 (41%), Gaps = 12/141 (8%)
Frame = +2
Query: 236 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETG--TIENTSLAQYD----------RL 379
DL I + K I+ ++D+L+NNAG++ T E+ Q+ L
Sbjct: 26 DLASLKSIREFAAKIIEEEERVDILINNAGVMRCPHWTTEDGFEMQFGVNHLGHFLLTNL 85
Query: 380 MNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVAL 559
+ +++ ++ + L G R + AY SK ++ FT+ ++
Sbjct: 86 LLDKLKASAPSRIINLSSLAHVAGHIDFDDLNWQTRKYNTKAAYCQSKLAIVLFTKELSR 145
Query: 560 XLAPKGVRVNCVNPXVILTEL 622
L GV VN ++P V TEL
Sbjct: 146 RLQGSGVTVNALHPGVARTEL 166
>AY268353-1|AAP42287.1| 199|Homo sapiens short-chain
dehydrogenase/reductase 10c protein.
Length = 199
Score = 35.5 bits (78), Expect = 0.15
Identities = 29/95 (30%), Positives = 41/95 (43%), Gaps = 1/95 (1%)
Frame = +2
Query: 260 EKIIKKTIDHYGKLDVLV-NNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL 436
E +++ +D G LD LV N+ G GT + A LM N S LT A+P L
Sbjct: 8 ESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATR-WLMQVNFVSYVQLTSRALPSL 66
Query: 437 LESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQF 541
+SKG G Y+ +K ++D F
Sbjct: 67 TDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGF 101
>DQ426886-1|ABD90542.1| 171|Homo sapiens retinol dehydrogenase 11
protein.
Length = 171
Score = 35.1 bits (77), Expect = 0.20
Identities = 25/96 (26%), Positives = 40/96 (41%), Gaps = 3/96 (3%)
Frame = +2
Query: 53 TMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSIT 232
T+ GKVV L++ GA++ L R+VE + V+K+ +
Sbjct: 36 TVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVL 95
Query: 233 A---DLTKESDIEKIIKKTIDHYGKLDVLVNNAGII 331
DL+ I K + L VL+NNAG++
Sbjct: 96 VRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVM 131
>CR457145-1|CAG33426.1| 157|Homo sapiens PECR protein.
Length = 157
Score = 34.7 bits (76), Expect = 0.27
Identities = 16/43 (37%), Positives = 25/43 (58%)
Frame = +2
Query: 491 FPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCVNPXVILTE 619
FP + ++A V T+ +AL A G+R+NCV P VI ++
Sbjct: 19 FPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQ 61
>X13440-1|CAA31792.1| 328|Homo sapiens protein ( Human mRNA for
17-beta-hydroxysteroid dehydrogenase (17-HSD) (EC
1.1.1.62). ).
Length = 328
Score = 33.5 bits (73), Expect = 0.62
Identities = 24/102 (23%), Positives = 43/102 (42%), Gaps = 1/102 (0%)
Frame = +2
Query: 293 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXX 469
G++DVLV NAG+ G +E +++ NV + +P + G
Sbjct: 83 GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTG 142
Query: 470 XXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCV 595
G+ P Y SK +++ +A+ L P GV ++ +
Sbjct: 143 SVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLI 184
>U34879-1|AAD05019.1| 328|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase protein.
Length = 328
Score = 33.5 bits (73), Expect = 0.62
Identities = 24/102 (23%), Positives = 43/102 (42%), Gaps = 1/102 (0%)
Frame = +2
Query: 293 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXX 469
G++DVLV NAG+ G +E +++ NV + +P + G
Sbjct: 83 GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTG 142
Query: 470 XXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCV 595
G+ P Y SK +++ +A+ L P GV ++ +
Sbjct: 143 SVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLI 184
>M84472-1|AAB16942.1| 328|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase protein.
Length = 328
Score = 33.5 bits (73), Expect = 0.62
Identities = 24/102 (23%), Positives = 43/102 (42%), Gaps = 1/102 (0%)
Frame = +2
Query: 293 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXX 469
G++DVLV NAG+ G +E +++ NV + +P + G
Sbjct: 83 GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTG 142
Query: 470 XXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCV 595
G+ P Y SK +++ +A+ L P GV ++ +
Sbjct: 143 SVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLI 184
>M36263-1|AAA35600.1| 328|Homo sapiens protein ( Human placental
17-beta-hydroxysteroid dehydrogenase mRNA, complete cds.
).
Length = 328
Score = 33.5 bits (73), Expect = 0.62
Identities = 24/102 (23%), Positives = 43/102 (42%), Gaps = 1/102 (0%)
Frame = +2
Query: 293 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXX 469
G++DVLV NAG+ G +E +++ NV + +P + G
Sbjct: 83 GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTG 142
Query: 470 XXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCV 595
G+ P Y SK +++ +A+ L P GV ++ +
Sbjct: 143 SVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLI 184
>M27138-1|AAB16941.1| 328|Homo sapiens protein ( Human estradiol 17
beta-dehydrogenase gene, complete cds. ).
Length = 328
Score = 33.5 bits (73), Expect = 0.62
Identities = 24/102 (23%), Positives = 43/102 (42%), Gaps = 1/102 (0%)
Frame = +2
Query: 293 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXX 469
G++DVLV NAG+ G +E +++ NV + +P + G
Sbjct: 83 GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTG 142
Query: 470 XXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCV 595
G+ P Y SK +++ +A+ L P GV ++ +
Sbjct: 143 SVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLI 184
>BC111935-1|AAI11936.1| 328|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 1 protein.
Length = 328
Score = 33.5 bits (73), Expect = 0.62
Identities = 24/102 (23%), Positives = 43/102 (42%), Gaps = 1/102 (0%)
Frame = +2
Query: 293 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXX 469
G++DVLV NAG+ G +E +++ NV + +P + G
Sbjct: 83 GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTG 142
Query: 470 XXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCV 595
G+ P Y SK +++ +A+ L P GV ++ +
Sbjct: 143 SVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLI 184
>BC104752-1|AAI04753.1| 328|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 1 protein.
Length = 328
Score = 33.5 bits (73), Expect = 0.62
Identities = 24/102 (23%), Positives = 43/102 (42%), Gaps = 1/102 (0%)
Frame = +2
Query: 293 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXX 469
G++DVLV NAG+ G +E +++ NV + +P + G
Sbjct: 83 GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTG 142
Query: 470 XXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVNCV 595
G+ P Y SK +++ +A+ L P GV ++ +
Sbjct: 143 SVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLI 184
>BC150182-1|AAI50183.1| 1192|Homo sapiens reticulon 4 protein.
Length = 1192
Score = 32.3 bits (70), Expect = 1.4
Identities = 17/46 (36%), Positives = 25/46 (54%)
Frame = +2
Query: 125 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 262
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 251 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 296
>AY123250-1|AAM64254.1| 986|Homo sapiens RTN4 isoform G protein.
Length = 986
Score = 32.3 bits (70), Expect = 1.4
Identities = 17/46 (36%), Positives = 25/46 (54%)
Frame = +2
Query: 125 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 262
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 45 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 90
>AY123249-1|AAM64253.1| 986|Homo sapiens RTN4 isoform F protein.
Length = 986
Score = 32.3 bits (70), Expect = 1.4
Identities = 17/46 (36%), Positives = 25/46 (54%)
Frame = +2
Query: 125 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 262
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 45 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 90
>AY123248-1|AAM64252.1| 986|Homo sapiens RTN4 isoform E protein.
Length = 986
Score = 32.3 bits (70), Expect = 1.4
Identities = 17/46 (36%), Positives = 25/46 (54%)
Frame = +2
Query: 125 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 262
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 45 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 90
>AY123247-1|AAM64251.1| 986|Homo sapiens RTN4 isoform D protein.
Length = 986
Score = 32.3 bits (70), Expect = 1.4
Identities = 17/46 (36%), Positives = 25/46 (54%)
Frame = +2
Query: 125 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 262
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 45 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 90
>AY123246-1|AAM64250.1| 986|Homo sapiens RTN4 isoform Ab protein.
Length = 986
Score = 32.3 bits (70), Expect = 1.4
Identities = 17/46 (36%), Positives = 25/46 (54%)
Frame = +2
Query: 125 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 262
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 45 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 90
>AY123245-1|AAM64249.1| 986|Homo sapiens RTN4 isoform Aa protein.
Length = 986
Score = 32.3 bits (70), Expect = 1.4
Identities = 17/46 (36%), Positives = 25/46 (54%)
Frame = +2
Query: 125 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 262
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 45 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 90
>AY102285-4|AAM64244.1| 986|Homo sapiens RNT4 protein.
Length = 986
Score = 32.3 bits (70), Expect = 1.4
Identities = 17/46 (36%), Positives = 25/46 (54%)
Frame = +2
Query: 125 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 262
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 45 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 90
>AY102285-1|AAM64243.1| 1192|Homo sapiens RTN4 protein.
Length = 1192
Score = 32.3 bits (70), Expect = 1.4
Identities = 17/46 (36%), Positives = 25/46 (54%)
Frame = +2
Query: 125 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 262
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 251 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 296
>AY102279-1|AAM64248.1| 1192|Homo sapiens RTN4 isoform A protein.
Length = 1192
Score = 32.3 bits (70), Expect = 1.4
Identities = 17/46 (36%), Positives = 25/46 (54%)
Frame = +2
Query: 125 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 262
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 251 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 296
>AJ251383-1|CAB99248.1| 1192|Homo sapiens Nogo-A protein protein.
Length = 1192
Score = 32.3 bits (70), Expect = 1.4
Identities = 17/46 (36%), Positives = 25/46 (54%)
Frame = +2
Query: 125 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 262
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 251 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 296
>AF333336-1|AAK20831.1| 986|Homo sapiens testis specific reticulon
5 protein protein.
Length = 986
Score = 32.3 bits (70), Expect = 1.4
Identities = 17/46 (36%), Positives = 25/46 (54%)
Frame = +2
Query: 125 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 262
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 45 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 90
>AF148537-1|AAG12176.1| 1192|Homo sapiens reticulon 4a protein.
Length = 1192
Score = 32.3 bits (70), Expect = 1.4
Identities = 17/46 (36%), Positives = 25/46 (54%)
Frame = +2
Query: 125 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 262
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 251 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 296
>AC092461-1|AAX93116.1| 818|Homo sapiens unknown protein.
Length = 818
Score = 32.3 bits (70), Expect = 1.4
Identities = 17/46 (36%), Positives = 25/46 (54%)
Frame = +2
Query: 125 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 262
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 65 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 110
>AB073359-1|BAE45717.1| 294|Homo sapiens NOGO-A protein.
Length = 294
Score = 32.3 bits (70), Expect = 1.4
Identities = 17/46 (36%), Positives = 25/46 (54%)
Frame = +2
Query: 125 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 262
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 50 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 95
>AB040462-1|BAB18927.1| 1192|Homo sapiens RTN-xL protein.
Length = 1192
Score = 32.3 bits (70), Expect = 1.4
Identities = 17/46 (36%), Positives = 25/46 (54%)
Frame = +2
Query: 125 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 262
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 251 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 296
>AB020693-1|BAA74909.2| 1233|Homo sapiens KIAA0886 protein protein.
Length = 1233
Score = 32.3 bits (70), Expect = 1.4
Identities = 17/46 (36%), Positives = 25/46 (54%)
Frame = +2
Query: 125 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 262
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 292 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 337
>Z97054-9|CAI42651.1| 169|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 169
Score = 31.5 bits (68), Expect = 2.5
Identities = 18/69 (26%), Positives = 33/69 (47%), Gaps = 6/69 (8%)
Frame = +2
Query: 233 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 394
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 395 RSIYYLTML 421
+ + L
Sbjct: 123 MGTFNVIRL 131
>AF069291-3|AAC62233.1| 188|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 188
Score = 29.9 bits (64), Expect = 7.6
Identities = 19/90 (21%), Positives = 36/90 (40%), Gaps = 2/90 (2%)
Frame = +2
Query: 59 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTL--SIT 232
+F GKV LS LGAQ + R ++ L+ ++ +I
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQ 115
Query: 233 ADLTKESDIEKIIKKTIDHYGKLDVLVNNA 322
D+ ++ + + I G ++++NNA
Sbjct: 116 CDVRDPDMVQNTVSELIKVAGHPNIVINNA 145
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 83,343,197
Number of Sequences: 237096
Number of extensions: 1740283
Number of successful extensions: 3102
Number of sequences better than 10.0: 205
Number of HSP's better than 10.0 without gapping: 2953
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3059
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6747805200
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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