Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P02_F_B23
(728 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9VXI1 Cluster: CG9914-PA; n=5; Diptera|Rep: CG9914-PA ... 281 9e-75
UniRef50_UPI0000588BF0 Cluster: PREDICTED: similar to 3-hydroxya... 237 3e-61
UniRef50_Q9Y2S2 Cluster: Lambda-crystallin homolog; n=30; Coelom... 225 1e-57
UniRef50_A7SBT1 Cluster: Predicted protein; n=2; Nematostella ve... 211 2e-53
UniRef50_Q1RLR0 Cluster: LOC570274 protein; n=4; Clupeocephala|R... 192 7e-48
UniRef50_A5G288 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 170 3e-41
UniRef50_Q2CEL4 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 161 2e-38
UniRef50_Q98LG2 Cluster: Mll1034 protein; n=5; Alphaproteobacter... 153 3e-36
UniRef50_Q6SEY0 Cluster: 3-hydroxyacyl-CoA dehydrogenase domain ... 150 4e-35
UniRef50_A5A8P0 Cluster: Putative uncharacterized protein; n=3; ... 149 7e-35
UniRef50_A1FMQ0 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 148 2e-34
UniRef50_A1B801 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 147 3e-34
UniRef50_Q0FUQ2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 134 3e-30
UniRef50_A4R503 Cluster: Putative uncharacterized protein; n=3; ... 134 3e-30
UniRef50_Q160J3 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 132 1e-29
UniRef50_A3VGB5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 128 1e-28
UniRef50_Q11EZ3 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 127 3e-28
UniRef50_Q7WLK3 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 125 1e-27
UniRef50_O29062 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; A... 123 5e-27
UniRef50_Q73Q34 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati... 117 3e-25
UniRef50_UPI000050F939 Cluster: COG1250: 3-hydroxyacyl-CoA dehyd... 117 3e-25
UniRef50_Q5LTH8 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 116 8e-25
UniRef50_Q93QG7 Cluster: Hydroxyacyl-CoA dehydrogenase; n=1; Bre... 115 1e-24
UniRef50_A5N111 Cluster: Hbd2; n=5; Clostridiales|Rep: Hbd2 - Cl... 115 1e-24
UniRef50_UPI00005102FD Cluster: COG1250: 3-hydroxyacyl-CoA dehyd... 114 2e-24
UniRef50_A6C4K6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 112 7e-24
UniRef50_Q9UX37 Cluster: 3-hydroxyacyl-CoA-dehydrogenase; n=4; S... 112 7e-24
UniRef50_Q1GEJ8 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 109 5e-23
UniRef50_Q97UK9 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2; S... 109 9e-23
UniRef50_Q39HR3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=24; ... 107 4e-22
UniRef50_A0GEI2 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 107 4e-22
UniRef50_Q24N80 Cluster: Putative uncharacterized protein; n=1; ... 106 6e-22
UniRef50_Q396V2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=9; B... 105 8e-22
UniRef50_A5D5N2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 105 1e-21
UniRef50_A1FNB9 Cluster: 3-hydroxyacyl-CoA dehydrogenase precurs... 105 1e-21
UniRef50_Q978T2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=5; A... 105 1e-21
UniRef50_UPI000023E2B1 Cluster: hypothetical protein FG00090.1; ... 104 2e-21
UniRef50_Q39LC4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; B... 103 3e-21
UniRef50_Q8G825 Cluster: Possible butyryl-CoA dehydrogenase; n=2... 103 6e-21
UniRef50_Q1DAC1 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 102 1e-20
UniRef50_Q2J5F5 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 101 1e-20
UniRef50_Q988C8 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1... 101 2e-20
UniRef50_O28011 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; A... 101 2e-20
UniRef50_Q5KYB5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=6... 100 3e-20
UniRef50_Q9D221 Cluster: Adult male hypothalamus cDNA, RIKEN ful... 98 2e-19
UniRef50_A3YAS5 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 98 2e-19
UniRef50_Q0UZL9 Cluster: Putative uncharacterized protein; n=1; ... 98 2e-19
UniRef50_Q5LPZ1 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 97 3e-19
UniRef50_A0RUN1 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C... 97 5e-19
UniRef50_UPI00015BAF7B Cluster: 3-hydroxyacyl-CoA dehydrogenase,... 96 7e-19
UniRef50_Q8XI27 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase N... 95 2e-18
UniRef50_A4FKS0 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 94 3e-18
UniRef50_A3M445 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 94 3e-18
UniRef50_Q5L0D2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3... 94 4e-18
UniRef50_Q9HKW7 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenas... 93 6e-18
UniRef50_A6CP14 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 92 1e-17
UniRef50_Q5V0V6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 92 1e-17
UniRef50_Q7WCB1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4... 91 2e-17
UniRef50_Q7D836 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 91 2e-17
UniRef50_Q2B4D1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 91 2e-17
UniRef50_Q4J0Z7 Cluster: 3-hydroxyacyl-CoA dehydrogenase, C-term... 91 3e-17
UniRef50_Q0LRY2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 91 3e-17
UniRef50_Q9YBW6 Cluster: 3-hydroxyacyl-CoA dehydrogenase/3-hydro... 90 4e-17
UniRef50_Q5HKI5 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 90 6e-17
UniRef50_O30218 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; A... 89 8e-17
UniRef50_Q46MP3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4... 89 1e-16
UniRef50_A1SPQ6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3... 89 1e-16
UniRef50_Q2UUZ5 Cluster: RIB40 genomic DNA, SC009; n=4; Trichoco... 88 2e-16
UniRef50_P76083 Cluster: Probable 3-hydroxybutyryl-CoA dehydroge... 88 2e-16
UniRef50_Q89HA7 Cluster: Blr6087 protein; n=6; Proteobacteria|Re... 87 3e-16
UniRef50_Q0FUM2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 87 3e-16
UniRef50_Q11E57 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 87 4e-16
UniRef50_A3STE1 Cluster: Putative hydroxlacyl-CoA dehydrogenase;... 87 5e-16
UniRef50_Q5V357 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; H... 87 5e-16
UniRef50_A0LSM1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5... 86 1e-15
UniRef50_O29077 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; c... 86 1e-15
UniRef50_Q891F6 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=3... 85 1e-15
UniRef50_Q28KL8 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 85 1e-15
UniRef50_Q4J6T7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 85 1e-15
UniRef50_A1IEK7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 85 2e-15
UniRef50_Q0RVG8 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; R... 85 2e-15
UniRef50_A0JTB4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=5; A... 85 2e-15
UniRef50_Q9KBD3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=8... 84 4e-15
UniRef50_Q397D0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3... 84 4e-15
UniRef50_Q0YNQ2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 84 4e-15
UniRef50_A5V325 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 84 4e-15
UniRef50_Q5UWD9 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; c... 84 4e-15
UniRef50_A4YDR4 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 83 5e-15
UniRef50_A4ALU9 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like pr... 83 9e-15
UniRef50_A2TU34 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4... 82 2e-14
UniRef50_Q16836 Cluster: Hydroxyacyl-coenzyme A dehydrogenase, m... 82 2e-14
UniRef50_Q9RZ10 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati... 81 2e-14
UniRef50_A2QXC7 Cluster: Contig An11c0270, complete genome. prec... 81 2e-14
UniRef50_Q0LZ25 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 81 4e-14
UniRef50_Q11TH9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 80 5e-14
UniRef50_A2QCM7 Cluster: Catalytic activity: precursor; n=5; Tri... 80 5e-14
UniRef50_A7D676 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 80 5e-14
UniRef50_A0LPA1 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 79 1e-13
UniRef50_A6ERZ1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 78 2e-13
UniRef50_A1SSP5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 78 2e-13
UniRef50_Q9XA30 Cluster: Putative 3-Hydroxyacyl-CoA dehydrogenas... 77 4e-13
UniRef50_Q67SZ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; S... 77 4e-13
UniRef50_Q62DG4 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 77 4e-13
UniRef50_Q1AV58 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 77 4e-13
UniRef50_Q02A28 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 77 4e-13
UniRef50_A0PRD1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase FadB... 77 4e-13
UniRef50_Q0C7S2 Cluster: Putative uncharacterized protein; n=1; ... 77 4e-13
UniRef50_Q12D24 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 77 6e-13
UniRef50_Q1QBD7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 76 8e-13
UniRef50_Q39NP5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5... 76 1e-12
UniRef50_Q2W2Y1 Cluster: Glyoxysomal fatty acid beta-oxidation m... 76 1e-12
UniRef50_A5IDB6 Cluster: 3-hydroxyacyl CoA dehydrogenase; n=9; G... 76 1e-12
UniRef50_Q9ADL9 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase; ... 75 1e-12
UniRef50_A4FGV2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 75 2e-12
UniRef50_Q9HRI4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7; c... 75 2e-12
UniRef50_Q84T13 Cluster: L-3-hydroxyacyl-CoA dehydrogenase subun... 74 4e-12
UniRef50_O69856 Cluster: Fatty acid oxidation complex alpha-subu... 73 5e-12
UniRef50_A4SW27 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7; B... 73 5e-12
UniRef50_A3U7V8 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C... 73 5e-12
UniRef50_Q68WH7 Cluster: Putative fatty acid oxidation complex t... 73 5e-12
UniRef50_A0JVH8 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 73 7e-12
UniRef50_A1CC71 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati... 73 1e-11
UniRef50_Q47M90 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5... 72 1e-11
UniRef50_A0QZR0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 72 1e-11
UniRef50_Q5P039 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; P... 72 2e-11
UniRef50_Q1ATL4 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 72 2e-11
UniRef50_A5V327 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 72 2e-11
UniRef50_A1SEZ9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 72 2e-11
UniRef50_A5VHQ1 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 71 2e-11
UniRef50_Q1IIH2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5... 71 3e-11
UniRef50_Q4PFL4 Cluster: Putative uncharacterized protein; n=1; ... 71 3e-11
UniRef50_A3YFA8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 71 4e-11
UniRef50_O44608 Cluster: Hydroxy-acyl-coa dehydrogenase protein ... 70 5e-11
UniRef50_Q3KCL0 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 70 7e-11
UniRef50_O29090 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; A... 70 7e-11
UniRef50_Q0SEM1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 69 9e-11
UniRef50_A0IJE2 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 69 9e-11
UniRef50_A5V4A1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 69 2e-10
UniRef50_A1I839 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 69 2e-10
UniRef50_P45364 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 69 2e-10
UniRef50_Q5KVJ3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=16; ... 68 2e-10
UniRef50_Q3A7N5 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 68 2e-10
UniRef50_A7PEM6 Cluster: Chromosome chr11 scaffold_13, whole gen... 68 3e-10
UniRef50_P45856 Cluster: Probable 3-hydroxybutyryl-CoA dehydroge... 68 3e-10
UniRef50_Q7VRZ0 Cluster: Probable enoyl-CoA hydratase/3-hydroxya... 67 5e-10
UniRef50_Q8FUX6 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 66 6e-10
UniRef50_Q39TJ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like; n... 66 6e-10
UniRef50_Q6V1N6 Cluster: PlmT8; n=1; Streptomyces sp. HK803|Rep:... 66 6e-10
UniRef50_Q876X5 Cluster: Dehydrogenase; n=7; Pezizomycotina|Rep:... 66 6e-10
UniRef50_Q6KYW3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 66 8e-10
UniRef50_A4SW21 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 66 1e-09
UniRef50_P34439 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenas... 66 1e-09
UniRef50_UPI00006A277A Cluster: UPI00006A277A related cluster; n... 65 1e-09
UniRef50_Q28UL9 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 65 1e-09
UniRef50_Q1YTH7 Cluster: Fatty oxidation complex, alpha subunit;... 65 1e-09
UniRef50_A6WDS7 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 65 2e-09
UniRef50_Q4J598 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD bi... 64 3e-09
UniRef50_Q1IMY8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 64 3e-09
UniRef50_O29815 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; A... 64 3e-09
UniRef50_Q83DW6 Cluster: Fatty oxidation complex, alpha subunit;... 64 4e-09
UniRef50_Q4Q939 Cluster: Trifunctional enzyme alpha subunit, mit... 64 4e-09
UniRef50_A2QA05 Cluster: Catalytic activity:; n=4; Trichocomacea... 64 4e-09
UniRef50_A1IFR8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 63 6e-09
UniRef50_A4RUY4 Cluster: Predicted protein; n=5; cellular organi... 63 6e-09
UniRef50_Q392L7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=9... 62 1e-08
UniRef50_A0QZQ9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 62 1e-08
UniRef50_Q5KBI5 Cluster: Short chain 3-hydroxyacyl-CoA dehydroge... 62 1e-08
UniRef50_Q45223 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=9... 62 1e-08
UniRef50_Q8KUG1 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=8; A... 62 2e-08
UniRef50_Q6D2L7 Cluster: Fatty acid oxidation complex subunit al... 62 2e-08
UniRef50_Q9RUA4 Cluster: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA... 61 2e-08
UniRef50_Q5LKF7 Cluster: Fatty oxidation complex, alpha subunit;... 61 2e-08
UniRef50_Q1ISD6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 61 2e-08
UniRef50_Q0SCS0 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2; A... 61 2e-08
UniRef50_A3ZZK1 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1... 61 2e-08
UniRef50_A1B712 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 61 2e-08
UniRef50_Q2S2J8 Cluster: Fatty oxidation complex, alpha subunit;... 61 3e-08
UniRef50_Q14G85 Cluster: Fusion product of 3-hydroxacyl-CoA dehy... 61 3e-08
UniRef50_Q9HJM0 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase r... 61 3e-08
UniRef50_Q8W1L6 Cluster: Peroxisomal fatty acid beta-oxidation m... 61 3e-08
UniRef50_Q5LVG3 Cluster: Enoyl-CoA hydratase/isomerase/3-hydroxy... 60 4e-08
UniRef50_Q2J6P6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=10; ... 60 4e-08
UniRef50_Q0FMY4 Cluster: Enoyl-CoA hydratase; n=1; Roseovarius s... 60 4e-08
UniRef50_A1WHE6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; V... 60 4e-08
UniRef50_A1SQH4 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 60 4e-08
UniRef50_Q2SGN8 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; H... 60 5e-08
UniRef50_Q06BB6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 60 5e-08
UniRef50_A1SXV8 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 60 5e-08
UniRef50_A0W3T3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 60 5e-08
UniRef50_Q7RZ80 Cluster: Putative uncharacterized protein NCU043... 60 5e-08
UniRef50_A3ZYI9 Cluster: Fatty oxidation complex, alpha subunit ... 60 7e-08
UniRef50_Q5LVD0 Cluster: Enoyl-CoA hydratase/isomerase/3-hydroxy... 59 1e-07
UniRef50_Q39D25 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=48; ... 59 1e-07
UniRef50_A0VLT7 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 58 2e-07
UniRef50_A7S4Z9 Cluster: Predicted protein; n=1; Nematostella ve... 58 2e-07
UniRef50_Q8YB80 Cluster: 3-HYDROXYBUTYRYL-COA DEHYDROGENASE; n=3... 58 2e-07
UniRef50_Q8FRT3 Cluster: Putative 3-hydroxybutyryl-CoA dehydroge... 58 3e-07
UniRef50_Q1D1F2 Cluster: Fatty oxidation complex, alpha subunit ... 58 3e-07
UniRef50_Q0SEV8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3... 58 3e-07
UniRef50_A3JQP6 Cluster: Acetoacetyl-CoA reductase; n=2; Alphapr... 57 4e-07
UniRef50_A0ISW5 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 57 4e-07
UniRef50_A0HAN1 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 57 4e-07
UniRef50_Q5V581 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; H... 57 4e-07
UniRef50_A7INS1 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 57 5e-07
UniRef50_A5IPA0 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 57 5e-07
UniRef50_Q8FX64 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 56 9e-07
UniRef50_A6GC68 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 56 9e-07
UniRef50_A5WEP3 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 56 9e-07
UniRef50_A1BCA2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 56 9e-07
UniRef50_A0Z5J4 Cluster: Enoyl-CoA hydratase; n=2; unclassified ... 56 9e-07
UniRef50_Q668V1 Cluster: Fatty acid oxidation complex subunit al... 56 9e-07
UniRef50_Q1GGC1 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 56 1e-06
UniRef50_A0J682 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 56 1e-06
UniRef50_Q47DJ5 Cluster: Enoyl-CoA hydratase/isomerase:3-hydroxy... 55 2e-06
UniRef50_A6GBG1 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C... 55 2e-06
UniRef50_A4WWF6 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 55 2e-06
UniRef50_Q67L77 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 55 2e-06
UniRef50_Q8ZAN0 Cluster: Fatty acid oxidation complex subunit al... 55 2e-06
UniRef50_Q5P607 Cluster: Fusion of 3-hydroxyacyl-CoA dehydrogena... 54 3e-06
UniRef50_A0LI43 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 54 3e-06
UniRef50_Q0RL76 Cluster: Putative 3-hydroxybutyryl-CoA dehydroge... 54 4e-06
UniRef50_A4BL13 Cluster: Fatty oxidation complex, alpha subunit;... 54 4e-06
UniRef50_A0LDJ8 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 54 4e-06
UniRef50_O17761 Cluster: Putative uncharacterized protein ech-8;... 54 4e-06
UniRef50_Q5P5K6 Cluster: Fusion of 3-hydroxyacyl-CoA dehydrogena... 54 5e-06
UniRef50_A3M4C7 Cluster: PaaC; n=1; Acinetobacter baumannii ATCC... 54 5e-06
UniRef50_A1IDF2 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C... 54 5e-06
UniRef50_A6UH30 Cluster: 3-hydroxybutyryl-CoA epimerase; n=2; Si... 53 6e-06
UniRef50_Q7WIS8 Cluster: Putative enoyl-CoA isomerase; n=2; Bord... 53 8e-06
UniRef50_Q6MM12 Cluster: Fatty oxidation complex, alpha subunit;... 53 8e-06
UniRef50_Q5NW50 Cluster: DitN-like 3-hydroxyacyl-CoA dehydrogena... 53 8e-06
UniRef50_Q1NHB4 Cluster: Fatty oxidation complex, alpha subunit;... 53 8e-06
UniRef50_Q1LBV6 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 53 8e-06
UniRef50_A6X670 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 52 1e-05
UniRef50_Q9L6L5 Cluster: Fatty acid oxidation complex subunit al... 52 1e-05
UniRef50_Q89SH2 Cluster: Blr2428 protein; n=7; Rhizobiales|Rep: ... 52 1e-05
UniRef50_Q3JZL6 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati... 52 1e-05
UniRef50_Q1Z537 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 52 1e-05
UniRef50_Q4DMG1 Cluster: Short chain 3-hydroxyacyl-coa dehydroge... 52 1e-05
UniRef50_O28262 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2; A... 52 1e-05
UniRef50_Q8FRN7 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 52 2e-05
UniRef50_Q3IIH0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4... 52 2e-05
UniRef50_Q11BV6 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 52 2e-05
UniRef50_A3T2M8 Cluster: Enoyl-CoA hydratase/isomerase/3-hydroxy... 51 3e-05
UniRef50_Q0YNJ7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 51 3e-05
UniRef50_A3VIL7 Cluster: Enoyl-CoA hydratase/isomerase:3-hydroxy... 51 3e-05
UniRef50_A6FFH1 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenas... 50 4e-05
UniRef50_A0K022 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 50 4e-05
UniRef50_Q67QQ5 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 50 6e-05
UniRef50_Q1INT0 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 50 6e-05
UniRef50_A7HED1 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 50 6e-05
UniRef50_Q01V22 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 50 8e-05
UniRef50_A1FD08 Cluster: 3-hydroxybutyryl-CoA epimerase; n=13; c... 50 8e-05
UniRef50_Q092W5 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C... 49 1e-04
UniRef50_Q28N18 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 49 1e-04
UniRef50_Q11ME9 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 49 1e-04
UniRef50_A4BGI3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; R... 49 1e-04
UniRef50_Q8EYS5 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=4; L... 48 2e-04
UniRef50_Q39CK1 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=44; ... 48 2e-04
UniRef50_Q2S396 Cluster: 3-hydroxyacyl-CoA dehydrogenase, C-term... 48 2e-04
UniRef50_A5UXI1 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 48 2e-04
UniRef50_Q5P5K3 Cluster: Alpha-subunit of fatty acid oxidation c... 48 3e-04
UniRef50_A6DTH3 Cluster: 3-hydroxyacyl-CoA dehydrogenase, C-term... 47 5e-04
UniRef50_Q0UJN7 Cluster: Predicted protein; n=1; Phaeosphaeria n... 47 5e-04
UniRef50_Q93HI5 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2; A... 46 7e-04
UniRef50_Q97HK2 Cluster: 3-Hydroxyacyl-CoA dehydrogenase; n=1; C... 46 0.001
UniRef50_Q1YHC5 Cluster: Putative 3-hydroxybutyryl-CoA dehydroge... 46 0.001
UniRef50_Q0SJP3 Cluster: Bifunctional 3-hydroxyacyl-CoA dehydrog... 46 0.001
UniRef50_Q2SGR6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; H... 46 0.001
UniRef50_Q08426 Cluster: Peroxisomal bifunctional enzyme (PBE) (... 46 0.001
UniRef50_Q13I86 Cluster: 3-hydroxybutyryl-CoA epimerase; n=11; B... 45 0.002
UniRef50_Q128W2 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 45 0.002
UniRef50_Q0EXX8 Cluster: Fatty oxidation complex, alpha subunit;... 45 0.002
UniRef50_Q2VHK2 Cluster: Oxidoreductase; n=11; Lactobacillales|R... 45 0.002
UniRef50_Q0SA65 Cluster: Possible 3-hydroxybutyryl-CoA dehydroge... 45 0.002
UniRef50_A3TT55 Cluster: Putative fatty acid oxidation complex a... 44 0.004
UniRef50_A7HHZ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 44 0.005
UniRef50_Q1EVV0 Cluster: Dihydrolipoyl dehydrogenase; n=6; Clost... 43 0.007
UniRef50_Q8PMV7 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7; X... 43 0.009
UniRef50_Q4Q3S6 Cluster: Enoyl-CoA hydratase/Enoyl-CoA isomerase... 43 0.009
UniRef50_Q9AF94 Cluster: 3-hydroxyacyl-CoA-dehydrogenase; n=1; A... 42 0.012
UniRef50_Q1GNH9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=7... 42 0.012
UniRef50_UPI0000E4974C Cluster: PREDICTED: hypothetical protein;... 42 0.015
UniRef50_Q0CYI1 Cluster: Predicted protein; n=1; Aspergillus ter... 41 0.036
UniRef50_Q88X11 Cluster: NADH peroxidase; n=1; Lactobacillus pla... 40 0.082
UniRef50_Q01UM7 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; S... 40 0.082
UniRef50_Q6MHW5 Cluster: Glucose-inhibited division protein; n=1... 39 0.11
UniRef50_Q8RC01 Cluster: UDP-N-acetyl-D-mannosaminuronate dehydr... 39 0.14
UniRef50_Q4FL01 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; B... 39 0.14
UniRef50_Q0C0V2 Cluster: Oxidoreductase, FAD-binding; n=2; Prote... 39 0.14
UniRef50_A3D4X7 Cluster: FAD dependent oxidoreductase; n=3; Shew... 38 0.19
UniRef50_Q8G3X6 Cluster: Possible class I pyridine nucleotide-di... 38 0.25
UniRef50_P14218 Cluster: Dihydrolipoyl dehydrogenase; n=65; cell... 38 0.25
UniRef50_Q8CXB6 Cluster: UDP-glucose:GDP-mannose dehydrogenase; ... 38 0.33
UniRef50_Q88YA7 Cluster: Bifunctional protein: amino acid aminot... 38 0.33
UniRef50_Q4A6P9 Cluster: Putative mercuric reductase; n=1; Mycop... 38 0.33
UniRef50_Q0SUA0 Cluster: Pyridine nucleotide-disulphide oxidored... 38 0.33
UniRef50_A6GIL3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 38 0.33
UniRef50_O34324 Cluster: Dihydrolipoyl dehydrogenase; n=13; Baci... 38 0.33
UniRef50_P38169 Cluster: Kynurenine 3-monooxygenase; n=4; Saccha... 38 0.33
UniRef50_Q82W31 Cluster: Phosphoribosylaminoimidazole carboxylas... 37 0.44
UniRef50_Q1FP37 Cluster: NADH:flavin oxidoreductase/NADH oxidase... 37 0.44
UniRef50_A6P2M7 Cluster: Putative uncharacterized protein; n=2; ... 37 0.44
UniRef50_A4XMY3 Cluster: Prephenate dehydrogenase; n=1; Caldicel... 37 0.44
UniRef50_UPI000018F68E Cluster: hypothetical protein Rm378p142; ... 37 0.58
UniRef50_Q9X0U4 Cluster: Glutamate synthase, beta subunit; n=5; ... 37 0.58
UniRef50_Q8CX86 Cluster: UDP-glucose:GDP-mannose dehydrogenase; ... 37 0.58
UniRef50_A1TEA9 Cluster: Putative uncharacterized protein; n=2; ... 37 0.58
UniRef50_Q9N5G1 Cluster: Dehydrogenases, short chain protein 15;... 37 0.58
UniRef50_Q834J0 Cluster: Dihydrolipoyl dehydrogenase; n=3; Lacto... 36 0.77
UniRef50_Q1IMR6 Cluster: UDP-glucose/GDP-mannose dehydrogenase; ... 36 0.77
UniRef50_Q121N3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 36 0.77
UniRef50_Q041G8 Cluster: Acetoin/pyruvate dehydrogenase complex,... 36 0.77
UniRef50_A3XHA5 Cluster: Regulatory protein; n=4; Flavobacteriac... 36 0.77
UniRef50_A3M5D5 Cluster: Dihydrolipoamide dehydrogenase; n=1; Ac... 36 0.77
UniRef50_Q8U0F8 Cluster: NDP-sugar dehydrogenase; n=4; Thermococ... 36 0.77
UniRef50_O83080 Cluster: D-lactate dehydrogenase; n=1; Treponema... 36 0.77
UniRef50_P35484 Cluster: Dihydrolipoyl dehydrogenase; n=3; Achol... 36 0.77
UniRef50_Q892P7 Cluster: Dihydrolipoamide dehydrogenase; n=3; Cl... 36 1.0
UniRef50_Q2RJ81 Cluster: 4Fe-4S ferredoxin, iron-sulfur binding ... 36 1.0
UniRef50_Q2GH13 Cluster: FAD-dependent oxidoreductase; n=6; Anap... 36 1.0
UniRef50_Q8GP50 Cluster: Eps11H; n=13; Lactobacillales|Rep: Eps1... 36 1.0
UniRef50_Q6RK69 Cluster: D-lactate dehydrogenase; n=1; Lactobaci... 36 1.0
UniRef50_A7BC28 Cluster: Putative uncharacterized protein; n=1; ... 36 1.0
UniRef50_A6VXM3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 36 1.0
UniRef50_A6LMV1 Cluster: Putative uncharacterized protein precur... 36 1.0
UniRef50_A3XPY3 Cluster: Putative uncharacterized protein; n=1; ... 36 1.0
UniRef50_A3LNF8 Cluster: Kynurenine 3-monooxygenase, mitochondri... 36 1.0
UniRef50_UPI00006A2AB5 Cluster: UPI00006A2AB5 related cluster; n... 36 1.3
UniRef50_Q3AEV2 Cluster: Prephenate dehydrogenase; n=1; Carboxyd... 36 1.3
UniRef50_Q3IBS8 Cluster: Iron-sulfur-binding protein, glutamate ... 36 1.3
UniRef50_Q1IUZ3 Cluster: UDP-glucose/GDP-mannose dehydrogenase; ... 36 1.3
UniRef50_Q0F8T2 Cluster: Salicylate hydroxylase; n=1; alpha prot... 36 1.3
UniRef50_Q0B0P7 Cluster: NADP oxidoreductase, coenzyme F420-depe... 36 1.3
UniRef50_Q0AI36 Cluster: 3-hydroxybutyryl-CoA epimerase; n=3; Ni... 36 1.3
UniRef50_A3DJQ8 Cluster: NADH:flavin oxidoreductase/NADH oxidase... 36 1.3
UniRef50_Q0V6D4 Cluster: Putative uncharacterized protein; n=1; ... 36 1.3
UniRef50_Q485S6 Cluster: Putative D-amino acid dehydrogenase, sm... 35 1.8
UniRef50_A5IXT8 Cluster: D-lactate dehydrogenase; n=3; Mycoplasm... 35 1.8
UniRef50_P77212 Cluster: Probable pyridine nucleotide-disulfide ... 35 1.8
UniRef50_P53267 Cluster: DASH complex subunit DAM1; n=2; Sacchar... 35 1.8
UniRef50_Q8E285 Cluster: Pyridine nucleotide-disulphide oxidored... 35 2.3
UniRef50_Q83EI9 Cluster: Thiamine biosynthesis oxidoreductase Th... 35 2.3
UniRef50_Q7NCM9 Cluster: Glr2949 protein; n=1; Gloeobacter viola... 35 2.3
UniRef50_Q6AA68 Cluster: UDP-glucose 6-dehydrogenase; n=3; root|... 35 2.3
UniRef50_A0V9H2 Cluster: 2-dehydropantoate 2-reductase precursor... 35 2.3
UniRef50_P72357 Cluster: D-lactate dehydrogenase; n=28; Bacilli|... 35 2.3
UniRef50_Q8F125 Cluster: Cell-division inhibitor; n=3; Bacteria|... 34 3.1
UniRef50_Q5FGZ4 Cluster: Dihydrolipoyl dehydrogenase; n=11; Rick... 34 3.1
UniRef50_Q0FK50 Cluster: Putative uncharacterized protein; n=1; ... 34 3.1
UniRef50_Q05FN5 Cluster: Dihydrodipicolinate synthase; n=1; Cand... 34 3.1
UniRef50_A7LYA0 Cluster: Putative uncharacterized protein; n=1; ... 34 3.1
UniRef50_A5IAB6 Cluster: Pyridine nucleotide-disulfide oxidoredu... 34 3.1
UniRef50_A7RTC7 Cluster: Predicted protein; n=1; Nematostella ve... 34 3.1
UniRef50_Q0UKG0 Cluster: Predicted protein; n=1; Phaeosphaeria n... 34 3.1
UniRef50_P12045 Cluster: Phosphoribosylaminoimidazole carboxylas... 34 3.1
UniRef50_UPI0000510280 Cluster: COG1249: Pyruvate/2-oxoglutarate... 34 4.1
UniRef50_Q9RW59 Cluster: Dehydrogenase, putative; n=2; Deinococc... 34 4.1
UniRef50_Q97PL8 Cluster: Oxidoreductase, pyridine nucleotide-dis... 34 4.1
UniRef50_Q4FKW7 Cluster: D-amino-acid dehydrogenase small chain;... 34 4.1
UniRef50_Q24PW4 Cluster: Dihydrolipoyl dehydrogenase; n=1; Desul... 34 4.1
UniRef50_Q1YK26 Cluster: Phosphoribosylaminoimidazole carboxylas... 34 4.1
UniRef50_A7DM30 Cluster: Multi-sensor hybrid histidine kinase; n... 34 4.1
UniRef50_A1SPH4 Cluster: UDP-glucose/GDP-mannose dehydrogenase; ... 34 4.1
UniRef50_A0YDQ2 Cluster: NADP oxidoreductase, coenzyme F420-depe... 34 4.1
UniRef50_A0HBX6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 34 4.1
UniRef50_Q92D17 Cluster: Lin1004 protein; n=10; Bacilli|Rep: Lin... 33 5.4
UniRef50_Q8XN08 Cluster: D-lactate dehydrogenase; n=4; Firmicute... 33 5.4
UniRef50_Q8A2W9 Cluster: Dihydrolipoyl dehydrogenase; n=7; Bacte... 33 5.4
UniRef50_Q3SL16 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 33 5.4
UniRef50_Q49111 Cluster: Dihydrolipoamide dehydrogenase; n=7; ro... 33 5.4
UniRef50_Q1DAE6 Cluster: NADP oxidoreductase, coenzyme F420-depe... 33 5.4
UniRef50_A6CF61 Cluster: Soluble pyridine nucleotide transhydrog... 33 5.4
UniRef50_A5V9L0 Cluster: FAD dependent oxidoreductase precursor;... 33 5.4
UniRef50_A4WXD4 Cluster: Dimethylmenaquinone methyltransferase; ... 33 5.4
UniRef50_A3UGW9 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 33 5.4
UniRef50_A0UKE0 Cluster: FAD dependent oxidoreductase precursor;... 33 5.4
UniRef50_A0M4X2 Cluster: Kynurenine-3-monooxygenase-like protein... 33 5.4
UniRef50_Q23ZE9 Cluster: FAD dependent oxidoreductase family pro... 33 5.4
UniRef50_Q22X26 Cluster: Putative uncharacterized protein; n=1; ... 33 5.4
UniRef50_A7TI21 Cluster: Putative uncharacterized protein; n=1; ... 33 5.4
UniRef50_Q8TWI7 Cluster: UDP-N-acetylmuramoylalanine-D-glutamate... 33 5.4
UniRef50_A3DNE3 Cluster: FAD-dependent pyridine nucleotide-disul... 33 5.4
UniRef50_P75393 Cluster: Dihydrolipoyl dehydrogenase; n=6; Mycop... 33 5.4
UniRef50_UPI000038D9FE Cluster: COG1249: Pyruvate/2-oxoglutarate... 33 7.2
UniRef50_UPI000023D207 Cluster: hypothetical protein FG05450.1; ... 33 7.2
UniRef50_Q98N90 Cluster: Mll0243 protein; n=1; Mesorhizobium lot... 33 7.2
UniRef50_Q836Q9 Cluster: 6-phosphogluconate dehydrogenase, decar... 33 7.2
UniRef50_Q6F8G8 Cluster: Putative uncharacterized protein; n=2; ... 33 7.2
UniRef50_Q30V14 Cluster: D-isomer specific 2-hydroxyacid dehydro... 33 7.2
UniRef50_Q7X2D3 Cluster: D-amino acid oxidase; n=1; Arthrobacter... 33 7.2
UniRef50_Q4AI87 Cluster: FAD-dependent pyridine nucleotide-disul... 33 7.2
UniRef50_Q222Q6 Cluster: FAD dependent oxidoreductase precursor;... 33 7.2
UniRef50_Q18CC1 Cluster: E3 component of acetoin dehydrogenase e... 33 7.2
UniRef50_Q08VR6 Cluster: NADP oxidoreductase, coenzyme f420-depe... 33 7.2
UniRef50_Q03CK2 Cluster: Predicted dinucleotide-binding enzyme; ... 33 7.2
UniRef50_A6NVP0 Cluster: Putative uncharacterized protein; n=1; ... 33 7.2
UniRef50_A6M0T5 Cluster: Amine oxidase; n=6; Clostridium|Rep: Am... 33 7.2
UniRef50_A6GD93 Cluster: UDP-N-acetylmuramoylalanine--D-glutamat... 33 7.2
UniRef50_A3PFJ2 Cluster: NAD binding site:D-amino acid oxidase; ... 33 7.2
UniRef50_A7T9W4 Cluster: Predicted protein; n=1; Nematostella ve... 33 7.2
UniRef50_A7EL57 Cluster: Putative uncharacterized protein; n=1; ... 33 7.2
UniRef50_Q8TZS4 Cluster: Glutamate synthase; n=78; cellular orga... 33 7.2
UniRef50_Q4J9Z6 Cluster: Conserved Crenarchaeal protein; n=3; Su... 33 7.2
UniRef50_A3H9B3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 33 7.2
UniRef50_P48638 Cluster: Glutathione reductase; n=57; Bacteria|R... 33 7.2
UniRef50_UPI0000E46E06 Cluster: PREDICTED: similar to MGC107852 ... 33 9.5
UniRef50_Q98PG2 Cluster: DIHYDROLIPOAMIDE DEHYDROGENASE; n=8; My... 33 9.5
UniRef50_Q8R9D9 Cluster: Dihydrolipoyl dehydrogenase; n=3; Therm... 33 9.5
UniRef50_Q87Q19 Cluster: D-amino acid dehydrogenase, small subun... 33 9.5
UniRef50_Q7UQS2 Cluster: Phosphoribosylaminoimidazole carboxylas... 33 9.5
UniRef50_Q7UHR8 Cluster: Probable monooxygenase; n=1; Pirellula ... 33 9.5
UniRef50_Q2RHM5 Cluster: Dihydrolipoyl dehydrogenase; n=4; Clost... 33 9.5
UniRef50_O66939 Cluster: D-lactate dehydrogenase; n=1; Aquifex a... 33 9.5
UniRef50_Q41B40 Cluster: Similar to Phytoene dehydrogenase and r... 33 9.5
UniRef50_Q1Q5P1 Cluster: Similar to NAD(P) oxidoreductase, FAD-c... 33 9.5
UniRef50_Q15P79 Cluster: FAD dependent oxidoreductase; n=1; Pseu... 33 9.5
UniRef50_Q04KN1 Cluster: UDP-N-acetyl-D-mannosaminuronic acid de... 33 9.5
UniRef50_A6TSA3 Cluster: Amine oxidase; n=1; Alkaliphilus metall... 33 9.5
UniRef50_A6Q6F0 Cluster: Putative uncharacterized protein; n=1; ... 33 9.5
UniRef50_A0YMN9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 33 9.5
UniRef50_A0UYP0 Cluster: Amine oxidase; n=1; Clostridium cellulo... 33 9.5
UniRef50_A2BMN3 Cluster: Polysaccharide biosynthesis protein; n=... 33 9.5
>UniRef50_Q9VXI1 Cluster: CG9914-PA; n=5; Diptera|Rep: CG9914-PA -
Drosophila melanogaster (Fruit fly)
Length = 315
Score = 281 bits (690), Expect = 9e-75
Identities = 129/205 (62%), Positives = 160/205 (78%)
Frame = +3
Query: 63 KSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRG 242
K+EK+GIVGSGLIGRSW+MLFASVGYQV +YD++ +Q++ A+ + +L LE GLLRG
Sbjct: 4 KNEKVGIVGSGLIGRSWSMLFASVGYQVVLYDILPEQVSTALTATQKELQDLEAKGLLRG 63
Query: 243 ELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXX 422
+L A++QF CI G+ DL VKGA+FVQEC+PE LDLKK +++ LD+VV NTI
Sbjct: 64 KLTAAQQFACISGTNDLKELVKGAIFVQECIPERLDLKKALYKQLDAVVGPNTILSSSTS 123
Query: 423 XXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPV 602
LK+K+ V+VSHPVNPPYYVPLVEIVPAPWTKPE KKTR +MEEIGQ+PV
Sbjct: 124 TFLPSLFSADLKNKANVLVSHPVNPPYYVPLVEIVPAPWTKPEWVKKTRALMEEIGQKPV 183
Query: 603 SLTREIDGFVLNRIQYAILDEVWRL 677
+L+REI+GF LNRIQYAIL+E WRL
Sbjct: 184 TLSREIEGFALNRIQYAILNETWRL 208
>UniRef50_UPI0000588BF0 Cluster: PREDICTED: similar to
3-hydroxyacyl-coa dehyrogenase; n=5; Coelomata|Rep:
PREDICTED: similar to 3-hydroxyacyl-coa dehyrogenase -
Strongylocentrotus purpuratus
Length = 316
Score = 237 bits (579), Expect = 3e-61
Identities = 108/205 (52%), Positives = 139/205 (67%)
Frame = +3
Query: 63 KSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRG 242
+S+KIGIVGSGLIGRSWAM+FAS G+ VT++D+ Q+++A++ IK QL L G+LRG
Sbjct: 2 ESQKIGIVGSGLIGRSWAMIFASAGFSVTIFDIEPSQVSNALKLIKSQLEELSESGMLRG 61
Query: 243 ELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXX 422
L QF IKGS + A+ GA FVQECV E L++K+KVF ++ V D I
Sbjct: 62 TLSVEAQFALIKGSNSMEEALAGASFVQECVFEKLEVKQKVFSEMEQYVSDGAILSSSSS 121
Query: 423 XXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPV 602
E LK ++Q I+SHP+NPPYY PLVEI+PAPWT +TR IME +GQ PV
Sbjct: 122 CIMPSQFTENLKRRNQCIISHPINPPYYAPLVEIIPAPWTDQSAIDRTRTIMESVGQVPV 181
Query: 603 SLTREIDGFVLNRIQYAILDEVWRL 677
+L +E+ GF NRIQYAI+ EVWRL
Sbjct: 182 TLKKEVPGFAANRIQYAIIAEVWRL 206
>UniRef50_Q9Y2S2 Cluster: Lambda-crystallin homolog; n=30;
Coelomata|Rep: Lambda-crystallin homolog - Homo sapiens
(Human)
Length = 319
Score = 225 bits (549), Expect = 1e-57
Identities = 105/216 (48%), Positives = 140/216 (64%)
Frame = +3
Query: 81 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKASE 260
IVGSG+IGRSWAMLFAS G+QV +YD+ +QI +A+E+I+ ++ LE G L+G L E
Sbjct: 11 IVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQAGSLKGSLSVEE 70
Query: 261 QFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXX 440
Q I G ++ AV+GA+ +QECVPE+L+LKKK+F LDS++DD I
Sbjct: 71 QLSLISGCPNIQEAVEGAMHIQECVPEDLELKKKIFAQLDSIIDDRVILSSSTSCLMPSK 130
Query: 441 XXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREI 620
GL H Q IV+HPVNPPYY+PLVE+VP P T P +T +M++IGQ P+ + +E+
Sbjct: 131 LFAGLVHVKQCIVAHPVNPPYYIPLVELVPHPETAPTTVDRTHALMKKIGQCPMRVQKEV 190
Query: 621 DGFVLNRIQYAILDEVWRLXXXXXXXXXXXXXXMSE 728
GFVLNR+QYAI+ E WRL MSE
Sbjct: 191 AGFVLNRLQYAIISEAWRLVEEGIVSPSDLDLVMSE 226
>UniRef50_A7SBT1 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 322
Score = 211 bits (515), Expect = 2e-53
Identities = 98/213 (46%), Positives = 141/213 (66%), Gaps = 3/213 (1%)
Frame = +3
Query: 48 MASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLEND 227
M S + K+ ++GSGLIGR+W+ LF+S GY V +YD V+ Q+ +A E I QL LE+
Sbjct: 1 MTSSTEKGKVAVIGSGLIGRAWSTLFSSAGYHVALYDTVSSQLVNAKEAIISQLQELESK 60
Query: 228 GLLRGE--LKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDN- 398
LL+G A E F+ + + DL A+ G +VQEC PENL+LKKKVFQNL++ + +
Sbjct: 61 ELLKGRHCKTAQEAFKLVTTTDDLPQALNGVFYVQECTPENLELKKKVFQNLEATLSSSE 120
Query: 399 TIXXXXXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIM 578
I E L+ + + IV+HP+NPPYYVPLVE++PAPWT V ++T ++M
Sbjct: 121 VILASSTSCIMPSKFTESLQLRQRCIVAHPINPPYYVPLVEVIPAPWTDASVIEQTIKLM 180
Query: 579 EEIGQQPVSLTREIDGFVLNRIQYAILDEVWRL 677
++IGQ PV L +E +GF++NR+QYA++ E WRL
Sbjct: 181 KDIGQSPVLLKKETNGFIVNRLQYALIAEAWRL 213
>UniRef50_Q1RLR0 Cluster: LOC570274 protein; n=4; Clupeocephala|Rep:
LOC570274 protein - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 327
Score = 192 bits (468), Expect = 7e-48
Identities = 99/225 (44%), Positives = 134/225 (59%)
Frame = +3
Query: 54 SKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGL 233
S K + I +VGSGLIGRSWAM+F S GY+V +YD Q + AI +I+ QL L+ +
Sbjct: 14 SSLKEKIITVVGSGLIGRSWAMVFLSGGYKVKLYDNKPGQASGAIAEIRKQLEELQQAKM 73
Query: 234 LRGELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXX 413
LRG L A+EQ + DL A+ GA FVQE V E+L+ K+ VF ++ +V ++ I
Sbjct: 74 LRGNLSATEQLSRLSSHEDLQQALDGAFFVQESVFEDLEAKQSVFHAVEELVSESVILSS 133
Query: 414 XXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQ 593
++++++ IVSHPVNPPYYV LVE+VP P T P V + +M ++GQ
Sbjct: 134 STSCLMPSNVFSQVQNRTRCIVSHPVNPPYYVRLVELVPHPETLPAVMEVAYSLMTDVGQ 193
Query: 594 QPVSLTREIDGFVLNRIQYAILDEVWRLXXXXXXXXXXXXXXMSE 728
PV L +EIDGF LNR+QYAI+ E WRL MSE
Sbjct: 194 APVRLRKEIDGFALNRVQYAIIAESWRLVQDGVISVKDIDLVMSE 238
>UniRef50_A5G288 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=2; Proteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Acidiphilium cryptum (strain JF-5)
Length = 312
Score = 170 bits (413), Expect = 3e-41
Identities = 81/202 (40%), Positives = 123/202 (60%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 251
KI +VG+GL+G +WA++FA G+ V VYD V AI I +L TLE GL+
Sbjct: 2 KIAVVGAGLVGSAWAIVFARAGHDVAVYDAVEGGADRAIGLIGDRLKTLEEVGLIEDAAA 61
Query: 252 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 431
A ++ ++ + LA AV A ++QE V E ++ K+++F LD+VV T+
Sbjct: 62 AGQR---VRVAASLADAVADAAYIQESVFETVEQKRQIFAALDAVVGPETLIGSSSSGIP 118
Query: 432 XXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLT 611
+ + + + +++HPVNPPY +P+VE+VPAPWT ++ R +ME +GQ+PV LT
Sbjct: 119 ASAFTDHVGCRERCLIAHPVNPPYLIPVVELVPAPWTAAATVQRVRALMESVGQEPVELT 178
Query: 612 REIDGFVLNRIQYAILDEVWRL 677
REI+GF LNR+Q +L E W+L
Sbjct: 179 REIEGFALNRLQGLLLAEAWKL 200
>UniRef50_Q2CEL4 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Rhodobacteraceae|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Oceanicola granulosus HTCC2516
Length = 312
Score = 161 bits (391), Expect = 2e-38
Identities = 82/202 (40%), Positives = 118/202 (58%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 251
K+ I+G+GLIG+SWA+ FA G VT++D A+ + L LE LL GE
Sbjct: 3 KVAIIGAGLIGQSWAIAFARGGCAVTLHDRDHAVADRALAVLPDALAALERMDLLGGET- 61
Query: 252 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 431
A I ++DLA AV+GA+ VQE PE L++K+ VF LD D + +
Sbjct: 62 ADAVGARIDAASDLADAVRGAIHVQENTPETLEVKRSVFAQLDDAADADAVIASSSSALL 121
Query: 432 XXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLT 611
+GL ++ +V+HP+NPP+ VP VE+VP P T E +TR +M IGQ P+ +
Sbjct: 122 PSAFTDGLAGAARCLVAHPLNPPHLVPAVELVPGPQTSAETVARTRALMSSIGQSPIETS 181
Query: 612 REIDGFVLNRIQYAILDEVWRL 677
RE++GFV+NR+Q A+LDE + L
Sbjct: 182 REVEGFVMNRLQGALLDEAFAL 203
>UniRef50_Q98LG2 Cluster: Mll1034 protein; n=5;
Alphaproteobacteria|Rep: Mll1034 protein - Rhizobium
loti (Mesorhizobium loti)
Length = 315
Score = 153 bits (372), Expect = 3e-36
Identities = 78/201 (38%), Positives = 114/201 (56%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
+ IVGSG IGR+WA+ FA G+ V ++D A + I+ L L + LLRG+
Sbjct: 4 VAIVGSGFIGRAWAISFARAGHDVRMWDQSPAATGGARDYIEGVLGDLAANDLLRGQ-SV 62
Query: 255 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 434
I DLA A+ A VQE PENLD+K++VF +D + TI
Sbjct: 63 DTVLGRIATVGDLAEALADAAHVQENTPENLDVKREVFSLIDRLAGPQTIIASSTSALLP 122
Query: 435 XXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTR 614
+ L+ + + +V HP+NPPY +P E+VPAPWT E +KTR + + G P+ + R
Sbjct: 123 SKFTDHLQGRHRCLVVHPINPPYLIPAAEVVPAPWTSAETLEKTRAFLIDAGHAPLVMRR 182
Query: 615 EIDGFVLNRIQYAILDEVWRL 677
E+DGF++NR+Q A+L+E +RL
Sbjct: 183 ELDGFIMNRLQGALLEEAFRL 203
>UniRef50_Q6SEY0 Cluster: 3-hydroxyacyl-CoA dehydrogenase domain
protein; n=1; uncultured bacterium 582|Rep:
3-hydroxyacyl-CoA dehydrogenase domain protein -
uncultured bacterium 582
Length = 322
Score = 150 bits (363), Expect = 4e-35
Identities = 77/201 (38%), Positives = 116/201 (57%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
+ +VG+GLIG WA++FA G+QVT+ D+ ++ A + + QL LE L
Sbjct: 17 VSVVGAGLIGCGWAIVFARAGWQVTLQDIDLAKLQGAPKVLAVQLRMLEQHDLCADPAGI 76
Query: 255 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 434
+ I +DL TAV +VQEC PE L LK+++F LD++ TI
Sbjct: 77 LAR---ISYESDLKTAVCEVDYVQECGPEVLGLKQELFSELDALTPPETILASSTSGLMA 133
Query: 435 XXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTR 614
L + + +V+HPVNPP+ VP+VEI P+ WT PE+ + ++M +GQ PV++ +
Sbjct: 134 SQFSAHLAGRHRALVAHPVNPPHLVPVVEISPSEWTDPEIVRVVVDVMTGVGQTPVTVQK 193
Query: 615 EIDGFVLNRIQYAILDEVWRL 677
EI GF+LNR+Q A+L+E RL
Sbjct: 194 EIPGFLLNRLQGALLNEALRL 214
>UniRef50_A5A8P0 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 284
Score = 149 bits (361), Expect = 7e-35
Identities = 65/176 (36%), Positives = 105/176 (59%)
Frame = +3
Query: 150 VYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKASEQFQCIKGSTDLATAVKGAVFVQE 329
+YD+ KQ+ A+E+++ L L+ GL RG L A E + +T L +K A+++QE
Sbjct: 1 MYDISEKQLQVALENVEKNLRKLDEHGLQRGNLSADEALLRVSTTTSLNEVMKNAIYMQE 60
Query: 330 CVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYV 509
E+L+ + + ++ +D + D TI +GL +K + ++ HPVNPP ++
Sbjct: 61 SALEDLNFRIQFYKVIDEIADPTTILASSTSTIPASKFTDGLINKERCLIVHPVNPPLFL 120
Query: 510 PLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRL 677
PL E+VPAPWT + + EIM + Q+PV L +E+ GFV+NR+Q+A+L E WRL
Sbjct: 121 PLTELVPAPWTSQDTVDRAAEIMRSVKQEPVKLKKEVLGFVVNRLQFALLAETWRL 176
>UniRef50_A1FMQ0 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=3; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Pseudomonas putida W619
Length = 320
Score = 148 bits (358), Expect = 2e-34
Identities = 77/202 (38%), Positives = 118/202 (58%), Gaps = 1/202 (0%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLR-GELK 251
I IVG+GLIGR+WA++FA G+ V ++D+ + + ++ I+ +L+ L LL L
Sbjct: 14 IAIVGAGLIGRAWAIVFARAGHPVRLHDMDLQTMQNSHAYIEARLNELAEFDLLNDAPLT 73
Query: 252 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 431
+ C+ DLA A++ V VQE V E ++ K +F +D++ + I
Sbjct: 74 VLARITCVP---DLADALRDVVLVQENVRETVEAKIDIFSRMDALAPKDAILASSTSWLP 130
Query: 432 XXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLT 611
+ L + + +V+HP NPPY VPLVE+ PAPWT+ EV + EI GQ PV L+
Sbjct: 131 ASEFTKDLPGRGRCVVAHPTNPPYLVPLVELCPAPWTESEVMVRAHEIYTAAGQSPVVLS 190
Query: 612 REIDGFVLNRIQYAILDEVWRL 677
REI GF+LNR+Q A+L+E ++L
Sbjct: 191 REIHGFLLNRVQAAVLNECFKL 212
>UniRef50_A1B801 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Rhodobacteraceae|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Paracoccus denitrificans (strain Pd 1222)
Length = 311
Score = 147 bits (356), Expect = 3e-34
Identities = 81/201 (40%), Positives = 110/201 (54%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
I IVG+GLIGR+WA +FA G+ V V+D+ + + DI + G + A
Sbjct: 4 IAIVGAGLIGRAWAFVFARAGFDVRVWDLDPQVLERLDGDIAAMVAQTAPFGQAGADPDA 63
Query: 255 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 434
+ I+ DLA A+ GA VQE PE L +K+++F LD + I
Sbjct: 64 TAAR--IRAVPDLAGALDGAELVQESGPEVLAIKRELFARLDGLAAAGVILASSSSALMA 121
Query: 435 XXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTR 614
EGL S+ +V HPVNPP+ VP+VEI PAP+T P + + R+I GQ PV L R
Sbjct: 122 SAFAEGLPGASRCLVGHPVNPPHLVPVVEIAPAPFTDPVITARARDIYARAGQVPVMLKR 181
Query: 615 EIDGFVLNRIQYAILDEVWRL 677
EIDGF+LNR+Q +L E RL
Sbjct: 182 EIDGFILNRLQAVVLAESLRL 202
>UniRef50_Q0FUQ2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Alphaproteobacteria|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Roseovarius sp. HTCC2601
Length = 316
Score = 134 bits (323), Expect = 3e-30
Identities = 72/202 (35%), Positives = 109/202 (53%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 251
KI I+GSG+IG SWA+++A G V +Y+ A++ ++ L + + LLR
Sbjct: 5 KIAILGSGVIGASWAIVYARSGCDVAIYERSEAFRDSAMQRLESSLAS--SASLLRDGET 62
Query: 252 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 431
+ I L AV GA FV EC+ ENLD K+++F L+ + I
Sbjct: 63 VQDVLARITLHDTLEAAVAGADFVHECIVENLDSKRQIFAALNDAAEPEAILASTTSSFP 122
Query: 432 XXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLT 611
L + + I+ HP PP+ +P+ EI PAP+T EV+++T M E GQ PV +
Sbjct: 123 VSHFASDLACRDRCIIVHPATPPHLLPVTEICPAPFTSAEVSERTTAFMRECGQIPVRIK 182
Query: 612 REIDGFVLNRIQYAILDEVWRL 677
+E++GFVLNR+Q A+L E+ L
Sbjct: 183 KEVEGFVLNRMQAALLVEMLTL 204
>UniRef50_A4R503 Cluster: Putative uncharacterized protein; n=3;
Sordariomycetes|Rep: Putative uncharacterized protein -
Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 330
Score = 134 bits (323), Expect = 3e-30
Identities = 75/205 (36%), Positives = 115/205 (56%), Gaps = 3/205 (1%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 251
K+ I+G G IG SWA LF + G +V+ +DV + E + L L + GL++
Sbjct: 6 KVAIIGCGSIGASWAALFLAQGLEVSAFDVNPSAESFLRELVANALPVLSSLGLVKSSQA 65
Query: 252 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 431
+ I+ +TD+ATA+K A FVQE PE LD K+K+F+ + ++VD +TI
Sbjct: 66 TAAD---IEFTTDMATALKNASFVQENGPERLDFKQKLFRGVANLVDPDTIIATSSSGLT 122
Query: 432 XXXXXEGLK--HKSQ-VIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPV 602
+GL+ HK + V+V HP NPP+ +PLVE+V T +T EE+G++ V
Sbjct: 123 CSSIQQGLEAQHKPERVVVGHPFNPPHLIPLVEVVGGEQTSQATISRTMGFYEEVGKKAV 182
Query: 603 SLTREIDGFVLNRIQYAILDEVWRL 677
+ +E+ G V NR+Q A++ EV L
Sbjct: 183 HIKKEVVGHVANRLQAALMREVMYL 207
>UniRef50_Q160J3 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=1; Roseobacter denitrificans OCh 114|Rep: Putative
3-hydroxyacyl-CoA dehydrogenase - Roseobacter
denitrificans (strain ATCC 33942 / OCh 114)
(Erythrobactersp. (strain OCh 114)) (Roseobacter
denitrificans)
Length = 331
Score = 132 bits (318), Expect = 1e-29
Identities = 67/201 (33%), Positives = 106/201 (52%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
+ I+G GLIG++WA +F G +VT+YD + + A + ++ L+ E
Sbjct: 19 VAIIGCGLIGQAWATVFLRAGMRVTLYDAASGLVEQAKAQVIERMTEFARFDLVTHETLE 78
Query: 255 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 434
I+ + L AV A ++QE E LD+K ++ + +D + +
Sbjct: 79 RAPAH-IELADTLEDAVSAADYIQESGSEALDVKIELTREIDRFAAPHVVIGSSTSGITA 137
Query: 435 XXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTR 614
E +K + + +V HP+NPP+ VPLVE+VPAPWT +++ IGQ P+ L R
Sbjct: 138 SRYSETIKGRERCLVVHPINPPHLVPLVEVVPAPWTAQSAVDTVHDLLSAIGQVPILLNR 197
Query: 615 EIDGFVLNRIQYAILDEVWRL 677
EIDGFV+NR+Q A+L E + L
Sbjct: 198 EIDGFVVNRLQGALLREAFHL 218
>UniRef50_A3VGB5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Rhodobacterales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Rhodobacterales bacterium HTCC2654
Length = 324
Score = 128 bits (310), Expect = 1e-28
Identities = 66/203 (32%), Positives = 108/203 (53%), Gaps = 1/203 (0%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITD-AIEDIKYQLHTLENDGLLRGEL 248
++ +G G +G WA +FA G++V +YD A I A+ I+ L L + + GE
Sbjct: 3 RVVCIGVGTVGCGWATVFARAGHEVVLYDADADAIAARALPRIEATLEQLGRE-MPTGET 61
Query: 249 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 428
A + + I+ + L A+ GA VQE V E+L +K+ +F + + D+ +
Sbjct: 62 PADIRAR-IRVAGSLEEALSGAEVVQESVREDLAIKRALFDEIGAAAPDDCLLLSSTSAL 120
Query: 429 XXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
+ H + +V HPVNPP ++PLVE+ P T PE ++ R E G +P+++
Sbjct: 121 PGSQFLSDIPHPERALVGHPVNPPSHIPLVELCATPLTAPETVERARRFYTEAGMEPITV 180
Query: 609 TREIDGFVLNRIQYAILDEVWRL 677
+EIDGF+LNR+QY ++ E L
Sbjct: 181 NKEIDGFILNRLQYTLVAEAMHL 203
>UniRef50_Q11EZ3 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=3; Bacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Mesorhizobium sp. (strain BNC1)
Length = 318
Score = 127 bits (306), Expect = 3e-28
Identities = 68/201 (33%), Positives = 107/201 (53%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
I IVG+G IG ++A+LFAS G V ++D + A +++ +L L L
Sbjct: 13 ISIVGAGSIGVAFAVLFASRGASVRIWDALPDAFDRAANELRSRLEMLAKASALSEP--P 70
Query: 255 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 434
E I +LA A+ GA VQEC PEN+DLK +F+ L + D+ +
Sbjct: 71 DEISSRISWHRNLAEALDGADLVQECAPENIDLKVDLFRWLADLTPDHVVLASSSSALIA 130
Query: 435 XXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTR 614
++ + +V+V HP NPPY +P++E+VP+P T + + EI +PV + R
Sbjct: 131 SLIAPDIEIRRRVLVGHPGNPPYLIPVIEVVPSPETAQAIIDRAFEIYRNSHLKPVLVRR 190
Query: 615 EIDGFVLNRIQYAILDEVWRL 677
E++GF+ NR+Q A+L E + L
Sbjct: 191 EVEGFIFNRLQGAVLREAYCL 211
>UniRef50_Q7WLK3 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=3; Bordetella|Rep: Putative 3-hydroxyacyl-CoA
dehydrogenase - Bordetella bronchiseptica (Alcaligenes
bronchisepticus)
Length = 313
Score = 125 bits (302), Expect = 1e-27
Identities = 68/202 (33%), Positives = 108/202 (53%), Gaps = 1/202 (0%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
+ ++G G+IG SWA++FA G +VT+ + A + + + E L G +
Sbjct: 4 VAVIGGGIIGASWAVVFARRGLEVTIVERDAACLAGLPARLAGMI---ERSASLLGAGEQ 60
Query: 255 SEQFQCIKGSTD-LATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 431
G+TD LA AV A +VQE V ENL LK+ +F LD++ + +
Sbjct: 61 PGDVAARIGATDALAAAVGRADYVQEAVSENLALKRTLFAELDALAPAHALLASSTSTYG 120
Query: 432 XXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLT 611
E L +++ +V+HP+ PP+ P+VE+ + WT P+V M +GQ PV +
Sbjct: 121 ASQFTEALAGRARCLVAHPMTPPHLSPVVEMAASAWTDPQVLAGAEAFMRSLGQHPVRIR 180
Query: 612 REIDGFVLNRIQYAILDEVWRL 677
+EI GFVLNR+Q A+L E++R+
Sbjct: 181 KEIPGFVLNRLQGALLMEMFRV 202
>UniRef50_O29062 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 315
Score = 123 bits (296), Expect = 5e-27
Identities = 65/203 (32%), Positives = 104/203 (51%), Gaps = 1/203 (0%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 251
K+ +G+G +G SWA LFA G V VYD + + A I + TL ++ E
Sbjct: 4 KVACIGAGTVGASWASLFAWRGCDVAVYDPFPEALNRAEASIARTVSTL-SEIFSGSEDD 62
Query: 252 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 431
+K + +L A+KGA +VQE E L++K+ +F+ +D++ + TI
Sbjct: 63 VKSALSRVKFTENLEEALKGAYYVQESAVEKLEVKRDLFEKMDAIAEPETILATSTSGLS 122
Query: 432 XXXXXEGL-KHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
KH + I +HP NPP+ +PLVE+VP T +KT E ME +G++P+ +
Sbjct: 123 ISEIQTAARKHPERCITAHPYNPPHLIPLVEVVPRKQTDESCTEKTVEFMERMGKKPIVV 182
Query: 609 TREIDGFVLNRIQYAILDEVWRL 677
+++ G V NR+ A+ E L
Sbjct: 183 KKDVPGMVANRLAAALWREAVNL 205
>UniRef50_Q73Q34 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putative;
n=1; Treponema denticola|Rep: 3-hydroxyacyl-CoA
dehydrogenase, putative - Treponema denticola
Length = 309
Score = 117 bits (282), Expect = 3e-25
Identities = 68/210 (32%), Positives = 107/210 (50%)
Frame = +3
Query: 48 MASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLEND 227
M K K K+ +VG G +G + +FA G+ V + + + A++ IK L+ +
Sbjct: 1 MIEKGKKIKVAVVGDGTMGHGISEVFAKAGHTVQIIGLNDASLKSALDRIKLSLNEFVAE 60
Query: 228 GLLRGELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIX 407
GL+ I STD+ A A+ + E +PEN+DLK + F L+ + +TI
Sbjct: 61 GLVSAS-DIDTIVGRISFSTDIQKAEDAAIVI-EALPENMDLKTETFGKLEKICPQDTIL 118
Query: 408 XXXXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEI 587
+ +K + +VI +H PP +PLVE+ AP T T E+++ I
Sbjct: 119 ATASGHSVSEVIAQ-VKKRDRVIATHFWFPPQLLPLVEVCGAPETSKATIDTTCELLKGI 177
Query: 588 GQQPVSLTREIDGFVLNRIQYAILDEVWRL 677
G++PV + +EIDGF+ NRIQ+A L E W L
Sbjct: 178 GKKPVVIDKEIDGFIGNRIQFAALREAWAL 207
>UniRef50_UPI000050F939 Cluster: COG1250: 3-hydroxyacyl-CoA
dehydrogenase; n=1; Brevibacterium linens BL2|Rep:
COG1250: 3-hydroxyacyl-CoA dehydrogenase -
Brevibacterium linens BL2
Length = 314
Score = 117 bits (281), Expect = 3e-25
Identities = 68/199 (34%), Positives = 107/199 (53%), Gaps = 2/199 (1%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
+ ++G+G IGRS+A LFA GY V V+D + + + +++ ++ D ++ A
Sbjct: 5 VAVIGAGTIGRSFAWLFARSGYPVQVFDP-RPDLAEVVTELQAEVSA---DAAAH-DMLA 59
Query: 255 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 434
SE I + + TAV GA FVQE PE+ K K+F + + + I
Sbjct: 60 SE-LGTISLAESVETAVAGASFVQESGPEDPQAKPKLFAQIAAAAPKDAIFATSSSTIPA 118
Query: 435 XXXXEGLKHK--SQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
L + ++VIV HP NPP+ +PLVE+VPAP T + ++ E G++PV+L
Sbjct: 119 SLIARHLPPEVAARVIVGHPFNPPHLMPLVEVVPAPATSSDTVERALEFYRSCGREPVAL 178
Query: 609 TREIDGFVLNRIQYAILDE 665
RE+ GFV NR+Q A++ E
Sbjct: 179 NREVRGFVGNRLQNALMKE 197
>UniRef50_Q5LTH8 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=16; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase family protein -
Silicibacter pomeroyi
Length = 487
Score = 116 bits (278), Expect = 8e-25
Identities = 69/201 (34%), Positives = 103/201 (51%), Gaps = 3/201 (1%)
Frame = +3
Query: 81 IVGSGLIGRSWAMLFASVGYQVTVYDV---VAKQITDAIEDIKYQLHTLENDGLLRGELK 251
I+G G+IG WA F G+ V V+D ++I + + + + L L +D L E K
Sbjct: 6 IIGGGVIGGGWAARFLLNGWDVRVFDPDPEAERKIGEVLANARRSLPGL-SDMPLPPEGK 64
Query: 252 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 431
S DL AV GA ++QE VPE LDLK KV++++ D I
Sbjct: 65 LSFH-------ADLGEAVTGAAWIQESVPERLDLKLKVYRSIQEACDPGAILGSSTSGFK 117
Query: 432 XXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLT 611
EG Q++V+HP NP Y +PL+E+V P PE+ ++ +EIM +GQ P+ +
Sbjct: 118 PSELQEGALRPGQIVVTHPFNPVYLLPLIELVTTPENSPEMIERAKEIMRGLGQFPLHVR 177
Query: 612 REIDGFVLNRIQYAILDEVWR 674
+EID + +R L+ VWR
Sbjct: 178 KEIDAHIADR----FLEAVWR 194
>UniRef50_Q93QG7 Cluster: Hydroxyacyl-CoA dehydrogenase; n=1;
Brevibacterium sp. HCU|Rep: Hydroxyacyl-CoA
dehydrogenase - Brevibacterium sp. HCU
Length = 316
Score = 115 bits (277), Expect = 1e-24
Identities = 64/201 (31%), Positives = 106/201 (52%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
+GI G+G IG ++A+LFA G+ V ++D + + I ++ L+ LL
Sbjct: 7 VGIFGAGSIGTAFALLFADAGFAVRIFDPDPSALERSRHVIDQRITELQRFTLLASN--P 64
Query: 255 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 434
SE + I+ + TA GA+ VQE PE++ K+ +F++L +V D TI
Sbjct: 65 SEVRELIEIVSSARTAASGAILVQEAGPEDVQTKQHIFEDLTAVTSDETILASASSAIPS 124
Query: 435 XXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTR 614
+ + + ++ HP NPPY + +VE+V P T+ + + ++ E+ G V + R
Sbjct: 125 SRFVD-VHSAFRSLIGHPGNPPYLLRVVELVGNPSTEEQTILRAGQLYEQAGLSAVRVNR 183
Query: 615 EIDGFVLNRIQYAILDEVWRL 677
E+DGFV NRIQ A+L E + L
Sbjct: 184 EVDGFVFNRIQGAVLREAYAL 204
>UniRef50_A5N111 Cluster: Hbd2; n=5; Clostridiales|Rep: Hbd2 -
Clostridium kluyveri DSM 555
Length = 319
Score = 115 bits (276), Expect = 1e-24
Identities = 61/199 (30%), Positives = 100/199 (50%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
+ + ++G+G +G L A G V ++ + IK L LE G ++ +
Sbjct: 4 KNVAVLGTGTMGNGIVQLCAESGLNVNMFGRTDASLERGFTSIKTSLKNLEEKGKIKTNI 63
Query: 249 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 428
+ E + IKG + AV+G FV EC+ E+L+LK++VF LD + I
Sbjct: 64 -SKEILKRIKGVKTIEEAVEGVDFVIECIAEDLELKQEVFSKLDEICAPEVILASNTSGL 122
Query: 429 XXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
KH +V+++H NPP ++PLVE+VP T + T + +E IG++ V +
Sbjct: 123 SPTDIAINTKHPERVVIAHFWNPPQFIPLVEVVPGKHTDSKTVDITMDWIEHIGKKGVKM 182
Query: 609 TREIDGFVLNRIQYAILDE 665
+E GF+ NR+Q A+L E
Sbjct: 183 RKECLGFIGNRLQLALLRE 201
>UniRef50_UPI00005102FD Cluster: COG1250: 3-hydroxyacyl-CoA
dehydrogenase; n=1; Brevibacterium linens BL2|Rep:
COG1250: 3-hydroxyacyl-CoA dehydrogenase -
Brevibacterium linens BL2
Length = 311
Score = 114 bits (274), Expect = 2e-24
Identities = 70/204 (34%), Positives = 106/204 (51%), Gaps = 2/204 (0%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLH-TLENDGLLRGEL 248
K+ I+G+G+IG +WA F + G+ VT +D A ++ Q+ LE G G++
Sbjct: 6 KVAILGTGVIGAAWATGFLTAGHTVTAFDPA----DGAEARLRSQVEGNLEVTG--EGDI 59
Query: 249 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 428
++ + GS LA +V A FVQE PE LD+K+ + DS V + I
Sbjct: 60 TSAMERLHFAGS--LAESVGDADFVQENGPERLDIKQSMLAETDSAVPASAIIASSTSGF 117
Query: 429 X-XXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVS 605
+ H +++V HP NP + VPLVE+VP P T EV K+ EI IG++P+
Sbjct: 118 APSELATKATNHPERIVVGHPFNPAHLVPLVELVPTPATPAEVVKRGLEIYRSIGKKPIL 177
Query: 606 LTREIDGFVLNRIQYAILDEVWRL 677
+ E+ G V NR+Q A+ E + L
Sbjct: 178 VRAELPGHVTNRLQAALWQEAYSL 201
>UniRef50_A6C4K6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Planctomyces maris DSM 8797|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Planctomyces maris DSM 8797
Length = 311
Score = 112 bits (270), Expect = 7e-24
Identities = 62/201 (30%), Positives = 102/201 (50%), Gaps = 2/201 (0%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLL--RG 242
++IGI+G+GLIG SWA FA+ G +V ++DV A E L L + L+ +
Sbjct: 2 QEIGILGAGLIGASWATFFAAQGLRVRIFDVNNTVKQQAQELSVQNLQRLADLELISRKD 61
Query: 243 ELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXX 422
A E+ + +L T V+ +VQE V E+ ++K V+Q + + I
Sbjct: 62 AATAEEKLNVVDSLAELLTDVE---YVQESVIEDYEIKADVYQQFEQYAPEAAILGSSSS 118
Query: 423 XXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPV 602
++H + +++HP NPP+ +PLVE+VP T E + +E + +G+ PV
Sbjct: 119 GLLMTRMQTVMQHPGRALIAHPFNPPHLIPLVELVPGEQTATETMETVKEFFQGLGKHPV 178
Query: 603 SLTREIDGFVLNRIQYAILDE 665
L RE+ G + NR+ A+ E
Sbjct: 179 ILNREVPGHIANRLAAAVWRE 199
>UniRef50_Q9UX37 Cluster: 3-hydroxyacyl-CoA-dehydrogenase; n=4;
Sulfolobaceae|Rep: 3-hydroxyacyl-CoA-dehydrogenase -
Sulfolobus solfataricus
Length = 324
Score = 112 bits (270), Expect = 7e-24
Identities = 60/203 (29%), Positives = 105/203 (51%), Gaps = 1/203 (0%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 251
K+ ++G+G+IG W L + GY+V +Y + + A+ + L L+N G++ E +
Sbjct: 10 KVAVIGAGVIGVGWTTLLLAKGYKVNLYTEKKETLEKALAKVSAYLVNLKNLGMINEEPE 69
Query: 252 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 431
+ + G T + A+ FV E + E+ KK +F+ LD+ + + I
Sbjct: 70 S--YITNLTGITKIDDAIHNVDFVIEAIIEDYTAKKNLFKLLDTQLPQDIIIASSTSGLL 127
Query: 432 XXXXXEGL-KHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
+ + +H + +++HP NPP+ +PLVEIVP T E TRE ME++ + V L
Sbjct: 128 MTEIQKAMIRHPERGVIAHPWNPPHLLPLVEIVPGEKTSKETVDLTREFMEKLDRVVVLL 187
Query: 609 TREIDGFVLNRIQYAILDEVWRL 677
+E+ GF+ NR+ +A+ E L
Sbjct: 188 RKEVPGFIGNRLAFALFREAVNL 210
>UniRef50_Q1GEJ8 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=17; Bacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase NAD-binding - Silicibacter sp. (strain
TM1040)
Length = 491
Score = 109 bits (263), Expect = 5e-23
Identities = 69/202 (34%), Positives = 100/202 (49%), Gaps = 4/202 (1%)
Frame = +3
Query: 81 IVGSGLIGRSWAMLFASVGYQVTVYDV---VAKQITDAIEDIKYQLHTLENDGLL-RGEL 248
I+G G+IG WA F G+ V V+D ++I D + + + L L N L G L
Sbjct: 7 IIGGGVIGGGWAARFLLNGWDVRVFDPDPEAERKIGDVLANARRSLPGLGNVALPPEGSL 66
Query: 249 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 428
E LA V+G +VQE VPE LDLK+KV+ L++ +
Sbjct: 67 SYHET---------LAETVQGVDWVQESVPERLDLKQKVYAELEAHAPGGAVIGSSTSGY 117
Query: 429 XXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
+G + +Q++V+HP NP Y +PLVE+V PE+ K + I+ EIG P+ L
Sbjct: 118 KPSQLQDGFTNAAQIVVAHPFNPVYLMPLVEVVTTDVNTPEMIAKAKAIITEIGMYPLHL 177
Query: 609 TREIDGFVLNRIQYAILDEVWR 674
+EID V +R L+ VWR
Sbjct: 178 KKEIDAHVADR----FLEAVWR 195
>UniRef50_Q97UK9 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2;
Sulfolobus|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Sulfolobus solfataricus
Length = 384
Score = 109 bits (261), Expect = 9e-23
Identities = 67/202 (33%), Positives = 104/202 (51%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
+KIG+VG+G +G A + A Y V+V D+ + A E I L+ G ++
Sbjct: 4 KKIGVVGAGTMGHGIAEVSALANYNVSVVDISWDFLNRAKERIMESLNKFYEKGQIKE-- 61
Query: 249 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 428
K + + I+ ST ++ A FV E VPE ++LK+KVF+ LDS+ +T
Sbjct: 62 KPEDIMKRIEFSTSY-DVMRDADFVIEAVPEIIELKRKVFETLDSITPSHTFLASNTSSI 120
Query: 429 XXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
E K K ++I H NPP + LVEIVP+ +T E + T ++ +++ + PV L
Sbjct: 121 PISTIAEVTKRKEKIIGMHFFNPPPIMKLVEIVPSKYTSDETIEVTIDLAKKMNKIPVKL 180
Query: 609 TREIDGFVLNRIQYAILDEVWR 674
E+ GFV NRI ++ E R
Sbjct: 181 KVEVPGFVSNRIFLRLMQEACR 202
>UniRef50_Q39HR3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=24;
Burkholderia|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 305
Score = 107 bits (256), Expect = 4e-22
Identities = 66/203 (32%), Positives = 105/203 (51%), Gaps = 1/203 (0%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 251
+I IVG+G+IG SWA + + G+ DVVA TD +L E+ GE +
Sbjct: 5 RIAIVGAGVIGASWAAFYLTQGF-----DVVA---TDPAPQADTRLR--ESLAAFLGE-R 53
Query: 252 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNT-IXXXXXXXX 428
A+E + DL A+ G FVQE PE LDLK+ +++ +D V+ + I
Sbjct: 54 AAELSARLSFDADLVRALDGVDFVQENGPERLDLKRALYRQMDDVLPAHVPIASSSSGLK 113
Query: 429 XXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
KH + +++HP NPP+ +PLVE+V T +V + ++ + +G+Q + L
Sbjct: 114 MSDIQTACDKHPERCLIAHPFNPPHLIPLVELVGGDATSQDVTARVKDFYDALGKQTIVL 173
Query: 609 TREIDGFVLNRIQYAILDEVWRL 677
+E+ G V NR+ A+ EV+ L
Sbjct: 174 NKEMTGHVANRLAAALFREVYHL 196
>UniRef50_A0GEI2 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Burkholderia|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Burkholderia phytofirmans
PsJN
Length = 317
Score = 107 bits (256), Expect = 4e-22
Identities = 64/197 (32%), Positives = 104/197 (52%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
IG+VG+GL+G A A G++ V+DV ++ + L L + G + K
Sbjct: 19 IGVVGTGLMGVGIATQSALHGHRTIVHDVDPARLASVAPKAQAVLDELIDAGRIDPAAKQ 78
Query: 255 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 434
+ + I+ +L + A FV E +PE L+LK +++ L ++ D+ I
Sbjct: 79 AALAR-IETHAEL-DVMASAQFVIEAIPEVLELKHRLYAALTQLLADDAILASNTSGFHP 136
Query: 435 XXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTR 614
L+ K + +++H NPP+ +PLVE+VP T PEV ++T +M IG +PV L +
Sbjct: 137 DQLAAPLRAKDRFVIAHFWNPPHMIPLVEVVPGTATAPEVTQQTAALMSAIGMEPVVLAK 196
Query: 615 EIDGFVLNRIQYAILDE 665
I GFV NR+Q+A+L E
Sbjct: 197 AIPGFVGNRLQFAMLRE 213
>UniRef50_Q24N80 Cluster: Putative uncharacterized protein; n=1;
Desulfitobacterium hafniense Y51|Rep: Putative
uncharacterized protein - Desulfitobacterium hafniense
(strain Y51)
Length = 313
Score = 106 bits (254), Expect = 6e-22
Identities = 63/202 (31%), Positives = 101/202 (50%)
Frame = +3
Query: 60 FKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLR 239
F++ K+ +VG+G++G A L+A G+QV +YD +Q+ A + I + L +GL
Sbjct: 2 FENWKLLVVGAGVMGSGIAQLYACKGFQVALYDKFPEQLDRAKQLIANNMENLIKEGLAT 61
Query: 240 GELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXX 419
E +A I T+L A V E V EN D+K++ F LD + + I
Sbjct: 62 QE-EAERTKTLISYETELEKCAPQADLVLESVFENADVKRETFAQLDKLCASDCILCSNT 120
Query: 420 XXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQP 599
+ H + I++H NPP+ + LVE+V P T E K + + ++G++P
Sbjct: 121 SASNIFEIAP-VSHPERQIITHYFNPPFIMDLVEVVMGPKTSDETLDKVKSFLIQVGKEP 179
Query: 600 VSLTREIDGFVLNRIQYAILDE 665
L + I GF++NRI AI E
Sbjct: 180 AVLKQYIPGFIVNRIATAITRE 201
>UniRef50_Q396V2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=9;
Bacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 317
Score = 105 bits (253), Expect = 8e-22
Identities = 62/204 (30%), Positives = 97/204 (47%), Gaps = 1/204 (0%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
+++ ++G+G+IG SWA LF + G V DV + + LE GL
Sbjct: 6 KRVAVIGTGVIGASWAALFLAKGLDVAATDVAPDAEARLRQYLDAAWPALEELGLAPAAS 65
Query: 249 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 428
+A F + DLA AV GA VQE PE +D K+ ++ LD+++ +
Sbjct: 66 RARLTF-----THDLAEAVAGAGLVQENGPERIDFKRTLYGQLDALLPPDVPIASSSSGL 120
Query: 429 XXXXXXEGLK-HKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVS 605
G H + ++ HP NPP+ +PLVEIV T + +K +G++ +
Sbjct: 121 TMSEIQTGCPAHPERCVIGHPFNPPHLIPLVEIVSGAQTSEQTVEKVTAFYTSLGKRTIR 180
Query: 606 LTREIDGFVLNRIQYAILDEVWRL 677
L +E+ G V NR+Q A+ EV L
Sbjct: 181 LHKEVPGHVANRLQAALWREVVHL 204
>UniRef50_A5D5N2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Pelotomaculum thermopropionicum SI|Rep:
3-hydroxyacyl-CoA dehydrogenase - Pelotomaculum
thermopropionicum SI
Length = 319
Score = 105 bits (252), Expect = 1e-21
Identities = 61/197 (30%), Positives = 96/197 (48%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
+ I+G+G +G S A G V + DV A + A I+ L + G +G
Sbjct: 7 LAIIGAGTMGHSIAAAALQHGVSVRLIDVSAPALETARRKIQSYLASAAGKGGGKGGAVP 66
Query: 255 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 434
++ ++A V GA V E VPE LDLKK++F LD + + I
Sbjct: 67 GHLAGVLETCMEMAAGVTGADMVIEAVPEKLDLKKEIFAQLDKLCPPSVILATNTSGLPI 126
Query: 435 XXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTR 614
+V+ +H P Y +PLVE+V + +T P+VA T ++ IG++PV + +
Sbjct: 127 TAIASAAARPERVLGTHFYMPAYLIPLVEVVCSDYTSPDVAGDTVAFLQSIGRKPVLVKK 186
Query: 615 EIDGFVLNRIQYAILDE 665
+I GF+ NR+Q+AI E
Sbjct: 187 DIPGFIGNRLQHAIARE 203
>UniRef50_A1FNB9 Cluster: 3-hydroxyacyl-CoA dehydrogenase precursor;
n=4; Proteobacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase
precursor - Pseudomonas putida W619
Length = 313
Score = 105 bits (252), Expect = 1e-21
Identities = 62/197 (31%), Positives = 107/197 (54%), Gaps = 2/197 (1%)
Frame = +3
Query: 81 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKASE 260
++G+GL+G A +FA G++V++YD A + A + + H L+ G+ + A+
Sbjct: 9 VIGAGLMGHGIAQVFAQAGHKVSLYDPDAATLDLAPQRVA---HNLDQMGIASAPILAN- 64
Query: 261 QFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXX 440
I TDL AV A V E VPE L+LK+K+F ++ +T+
Sbjct: 65 ----IALFTDLREAVSNADIVIEAVPERLELKQKLFADIAGFAPPHTVLASNTSVIPITE 120
Query: 441 XXE--GLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTR 614
E G + +++++ +H NPP+ VPLVE+V T V + T E+++ +G+ PV + R
Sbjct: 121 IGEMLGSEARARLVGTHWWNPPHLVPLVEVVRTEHTSLSVFESTFELLQSLGKSPVKVNR 180
Query: 615 EIDGFVLNRIQYAILDE 665
++ GF+ NR+Q+A+ E
Sbjct: 181 DVAGFIGNRLQHAMWRE 197
>UniRef50_Q978T2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=5;
Archaea|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Thermoplasma volcanium
Length = 659
Score = 105 bits (252), Expect = 1e-21
Identities = 59/191 (30%), Positives = 96/191 (50%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 251
K+ ++GSG++G A A GY V + D+ + A +I L L G L + K
Sbjct: 5 KVTVIGSGIMGHGIAETIALAGYDVNLEDISDDVLAKAKAEIDASLDRLVKSGKLSDKTK 64
Query: 252 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 431
+ T + +VK A V E VPE LD+K++VF LD ++ I
Sbjct: 65 VLGRIHYF---TSIPESVKDADLVIEAVPEILDIKRQVFAQLDQSTKEDAILATNTSNIR 121
Query: 432 XXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLT 611
EG+K K +V+ H NPP + LVE++ + +T+ EV + + ++IG+ P+ +
Sbjct: 122 LTEIAEGVKKKGKVVGMHFFNPPVVLKLVEVIRSDYTEDEVFEAVYDFSKKIGKIPIKVY 181
Query: 612 REIDGFVLNRI 644
++ GFV+NRI
Sbjct: 182 KDTPGFVVNRI 192
>UniRef50_UPI000023E2B1 Cluster: hypothetical protein FG00090.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG00090.1 - Gibberella zeae PH-1
Length = 320
Score = 104 bits (250), Expect = 2e-21
Identities = 63/203 (31%), Positives = 99/203 (48%), Gaps = 2/203 (0%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL-K 251
+ IVG G+IG WA+LF S G +V + D A E +K L + RG K
Sbjct: 8 VAIVGCGVIGMGWAVLFMSCGLKVIISDPA----DGAHESLKRYLEQARSFFEERGNFDK 63
Query: 252 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNT-IXXXXXXXX 428
S ++ + D+ + FVQE PE ++ K+ + + LD I
Sbjct: 64 LSSNYEFVD---DILPLLPEVDFVQENGPERVEFKQSLMEKLDENTRPGVAIASSSSGLP 120
Query: 429 XXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
+ K S++++ HP NPP+ +PLVE+VP P T +V + +G++P+ L
Sbjct: 121 SSAFIQKCKKDPSRILIGHPFNPPHLIPLVEVVPHPGTSSDVVSSALAFYKSLGKKPILL 180
Query: 609 TREIDGFVLNRIQYAILDEVWRL 677
+E+ GFV NR+Q AI +E + L
Sbjct: 181 HQEVPGFVSNRLQAAINNEAYSL 203
>UniRef50_Q39LC4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Burkholderia sp. 383|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 333
Score = 103 bits (248), Expect = 3e-21
Identities = 61/203 (30%), Positives = 99/203 (48%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
E +GI+G+G IG SWA LF + G +V VYD + + +++ +LE GL R
Sbjct: 12 EVVGILGAGTIGASWAALFLAAGLEVDVYDPSPEGEAFVRDYVRHAWPSLERLGLARRGD 71
Query: 249 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 428
+F AV A FVQE VPE +++K +++ ++ +D I
Sbjct: 72 PGRLRFVATPEE-----AVARAQFVQESVPERIEIKHALYRRIEDHLDPRAIVCSSASGL 126
Query: 429 XXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
G K+ + I+ HP NPP+ +PLVE++ T+P V + + G+ + +
Sbjct: 127 LVKEMQAGWKNPGRFILGHPFNPPHLIPLVELLGNEKTEPGVLELAEQFYAACGKITIRV 186
Query: 609 TREIDGFVLNRIQYAILDEVWRL 677
+E+ G V NR+Q A+ E L
Sbjct: 187 NKEVPGHVANRLQAALWREAIHL 209
>UniRef50_Q8G825 Cluster: Possible butyryl-CoA dehydrogenase; n=2;
Bifidobacterium longum|Rep: Possible butyryl-CoA
dehydrogenase - Bifidobacterium longum
Length = 319
Score = 103 bits (246), Expect = 6e-21
Identities = 61/199 (30%), Positives = 94/199 (47%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
I VG+G +G + + FA GY V + + A++ I+ GLL+
Sbjct: 11 IANVGTGTMGHAITLQFALAGYPVHLVGRSEASLEKAMKAIRSDAEDFAEAGLLKAGDTV 70
Query: 255 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 434
I G D A+ V FV E V ENLD+KK V+ ++ + I
Sbjct: 71 DTVLARITGYADYASGVADVDFVIESVAENLDVKKSVWTEVEHAAPKDAILSTNTSGLSP 130
Query: 435 XXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTR 614
+ H + +V+H NP +PLVE+VP T P+V T ++M +IG++P + +
Sbjct: 131 TALQSVMGHPERFVVAHFWNPAQLMPLVEVVPGEKTDPKVVDITFDLMAKIGKKPAKIKK 190
Query: 615 EIDGFVLNRIQYAILDEVW 671
E GFV NR+Q A+L E +
Sbjct: 191 ESLGFVGNRLQLAVLREAF 209
>UniRef50_Q1DAC1 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=1; Myxococcus xanthus DK 1622|Rep: Putative
3-hydroxyacyl-CoA dehydrogenase - Myxococcus xanthus
(strain DK 1622)
Length = 321
Score = 102 bits (244), Expect = 1e-20
Identities = 61/203 (30%), Positives = 100/203 (49%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
++IG+VG G +G A+ A G QV +Y+ A A ++ L GLL E
Sbjct: 7 KRIGMVGGGAMGCGIALELAIAGRQVVLYNTRADSSERARAKLERDASLLVETGLLAPE- 65
Query: 249 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 428
+A I+ +T LA A V E +PE+L LK+++F+ LD + +T+
Sbjct: 66 QAPAAIGRIRRTTVLAEAAVEQDLVIESIPEDLALKQQLFRELDQLAAPDTLLATNTTAL 125
Query: 429 XXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
+V+ +H P + +PLV+I+P T P+ + R +EE+G+ PV
Sbjct: 126 SVTAIARDCTRPERVLSAHYYLPAHLIPLVDIIPGEKTSPDAVETVRRFIEELGKSPVVF 185
Query: 609 TREIDGFVLNRIQYAILDEVWRL 677
+R++ G V R+Q A++ E RL
Sbjct: 186 SRDVPGSVGPRLQQALIGEAIRL 208
>UniRef50_Q2J5F5 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=3; Actinomycetales|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Frankia sp. (strain CcI3)
Length = 323
Score = 101 bits (243), Expect = 1e-20
Identities = 59/198 (29%), Positives = 91/198 (45%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 251
++ ++G+G IG W LF + GY+V V + IE + + L GL
Sbjct: 11 RVAVIGAGSIGLGWITLFLAHGYRVRVNSTRSN-----IETVIHDALRLFTPGLPGASRD 65
Query: 252 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 431
++ ++ DL AV VQE PENL++K+ +F L+ T+
Sbjct: 66 PADLAGRLEIEPDLERAVADVAVVQENTPENLEIKQDLFARLEKHAAAGTLLLSSTSTML 125
Query: 432 XXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLT 611
+ + S +IV HP NPP+ +PLVE+V + P+ E +G+ PV L
Sbjct: 126 PADLGARMDNPSHLIVGHPFNPPHVIPLVEVVGDTTSDPDAVSAAAEFYRSVGKTPVVLR 185
Query: 612 REIDGFVLNRIQYAILDE 665
R I F NR+Q A+L E
Sbjct: 186 RPIAAFAANRLQSALLQE 203
>UniRef50_Q988C8 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1;
Mesorhizobium loti|Rep: 3-hydroxybutyryl-coA
dehydrogenase - Rhizobium loti (Mesorhizobium loti)
Length = 309
Score = 101 bits (242), Expect = 2e-20
Identities = 58/197 (29%), Positives = 94/197 (47%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
I I+G G +G A A G QV YDV AIE + L E G
Sbjct: 5 IAIIGLGTMGPGMAARLARGGLQVVAYDVAPA----AIERARSMLSVAETVLDALGIALP 60
Query: 255 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 434
S ++ + D+ AV GA V E VPEN+ +K V++ +D ++ +TI
Sbjct: 61 SAGVGTVRFTDDIGDAVSGADLVIENVPENISIKADVYRTIDGLIGQDTIVASDTSGIPI 120
Query: 435 XXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTR 614
+ + +++ H NPP+ +P++E++ T P+ R+++ IG PV + +
Sbjct: 121 TKLQAHISYPERMVGMHWSNPPHIIPMIEVIAGEKTAPQTVATIRDLIRSIGLLPVVVKK 180
Query: 615 EIDGFVLNRIQYAILDE 665
++ GFV NR+ YA+L E
Sbjct: 181 DVPGFVENRVLYALLRE 197
>UniRef50_O28011 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 668
Score = 101 bits (242), Expect = 2e-20
Identities = 59/206 (28%), Positives = 101/206 (49%)
Frame = +3
Query: 30 VASTVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQL 209
V + M + + + + ++G+GL+G A + A GY VT+ D+ + + + IK L
Sbjct: 5 VKQVINMDVRERIKTVAVLGAGLMGHGIAEVCAMAGYNVTMRDIKQEFVDRGMNMIKESL 64
Query: 210 HTLENDGLLRGELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVV 389
LE G ++ A E IK + DL AVK A V E VPE +++KK+V++ +D +
Sbjct: 65 AKLEQKGKIKS---AEEVLSRIKPTVDLEEAVKDADLVIEAVPEVVEIKKQVWEEVDKLA 121
Query: 390 DDNTIXXXXXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTR 569
+ I + + H NPP + LVE++ T EV
Sbjct: 122 KPDCIFTSNTSTMRITMLADFTSRPEKFAGLHFFNPPVLMRLVEVIRGEKTSDEVMDLLV 181
Query: 570 EIMEEIGQQPVSLTREIDGFVLNRIQ 647
E ++ IG+ PV + +++ GF++NR+Q
Sbjct: 182 EFVKSIGKTPVRVEKDVPGFIVNRVQ 207
>UniRef50_Q5KYB5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=6;
Bacillaceae|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Geobacillus kaustophilus
Length = 287
Score = 100 bits (240), Expect = 3e-20
Identities = 65/204 (31%), Positives = 106/204 (51%), Gaps = 3/204 (1%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
E++ +VGSG++GR A + A G+Q T+ D+ +Q+ A ++I ++ G+ RG+L
Sbjct: 3 ERLVVVGSGVMGRGIAYVGAVGGFQTTLVDIKQEQLESAQKEIA----SIFEQGVARGKL 58
Query: 249 KASEQFQC---IKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXX 419
SE+ + + S DLA AV+ A V E VPE L+LKK+VF+ +D+ +
Sbjct: 59 TDSERQEAEARLSYSLDLAAAVRDADLVIEAVPEKLELKKQVFETIDAHAPASCYFATNT 118
Query: 420 XXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQP 599
K +VI H NP + + LVEI+ T E A+ +E E +G++
Sbjct: 119 STMSPTEIGSFTKRPERVIAMHFFNPVHKMKLVEIIRGLETSDETAQVAKEAAERMGKET 178
Query: 600 VSLTREIDGFVLNRIQYAILDEVW 671
V + E GFV +RI + +E +
Sbjct: 179 V-VVNEFPGFVTSRISALVGNEAF 201
>UniRef50_Q9D221 Cluster: Adult male hypothalamus cDNA, RIKEN
full-length enriched library, clone:A230106J09
product:crystallin, lamda 1, full insert sequence; n=3;
Euarchontoglires|Rep: Adult male hypothalamus cDNA,
RIKEN full-length enriched library, clone:A230106J09
product:crystallin, lamda 1, full insert sequence - Mus
musculus (Mouse)
Length = 140
Score = 98.3 bits (234), Expect = 2e-19
Identities = 46/83 (55%), Positives = 62/83 (74%)
Frame = +3
Query: 81 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKASE 260
IVGSGLIGRSWAMLFAS G++V +YD+ +QITDA+E+I+ ++ +LE G L+G L A
Sbjct: 11 IVGSGLIGRSWAMLFASGGFKVKLYDIEQQQITDALENIRKEMKSLEQSGSLKGSLSAER 70
Query: 261 QFQCIKGSTDLATAVKGAVFVQE 329
Q I G +LA AV+GAV +Q+
Sbjct: 71 QLSLISGCGNLAEAVEGAVHIQQ 93
>UniRef50_A3YAS5 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=1; Marinomonas sp. MED121|Rep: Putative
3-hydroxyacyl-CoA dehydrogenase - Marinomonas sp. MED121
Length = 323
Score = 97.9 bits (233), Expect = 2e-19
Identities = 58/199 (29%), Positives = 93/199 (46%), Gaps = 1/199 (0%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 251
K+G++G+G+IG +WA+ + +G +V YD + + T+E GL G K
Sbjct: 12 KVGVIGTGVIGGAWALHYLRMGMEVVAYDPGPNSKEKLLTMVDNIWPTIEKLGLREGASK 71
Query: 252 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 431
+F + LA V+ +QE PE LD K+ +F +LD +V + +
Sbjct: 72 DKLRF--VDSLDALANQVE---VIQESTPERLDAKRSLFADLDCIVPADVVIISSTSGFA 126
Query: 432 XXXXXEGLKHK-SQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
L+ + + +V HP NPPY VP E+ T EV T E +Q +
Sbjct: 127 MTDMANELETQPDRFVVGHPFNPPYLVPFCEVCGGERTSQEVVDWTAAFYEATEKQVAKM 186
Query: 609 TREIDGFVLNRIQYAILDE 665
+E+ GF+ NR+Q A+ E
Sbjct: 187 DKELPGFIGNRLQEALWRE 205
>UniRef50_Q0UZL9 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 308
Score = 97.9 bits (233), Expect = 2e-19
Identities = 60/200 (30%), Positives = 107/200 (53%), Gaps = 2/200 (1%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAML-FASVG-YQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGE 245
K+ ++G+G IG S+A A + Q+T+YD ++ IE+ L G +
Sbjct: 7 KVTLIGTGTIGLSFAAFHLAKLSPSQLTIYDT-RSDLSTYIEEF---LPKFFESGKSPAD 62
Query: 246 LKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 425
L SE I+ + L AV + +QE PENLD+K+K+++ ++ ++ +
Sbjct: 63 L--SE----IRLAVTLQEAVSDSHIIQESGPENLDVKRKLWKEVEKYAPNDALLWSSTSG 116
Query: 426 XXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVS 605
+ ++ K++++V HP NPP+ +PL+E+VP+ T V +T++ E G+ P+
Sbjct: 117 IPASQQAQDMQDKTRLLVVHPYNPPHIMPLLELVPSSETSDTVISRTQDFWRERGRVPIH 176
Query: 606 LTREIDGFVLNRIQYAILDE 665
+ RE GFV NR+ +A+L E
Sbjct: 177 IKRETTGFVANRLAFALLRE 196
>UniRef50_Q5LPZ1 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=5; Bacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase family protein - Silicibacter pomeroyi
Length = 317
Score = 97.5 bits (232), Expect = 3e-19
Identities = 62/200 (31%), Positives = 94/200 (47%), Gaps = 2/200 (1%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVY--DVVAKQITDAIEDIKYQLHTLENDGLLRGE 245
++ +G G IG WA F + GY VT Y D + I D + +L GL G
Sbjct: 11 RVTSIGGGPIGGGWAAHFLARGYDVTSYLHDRAEEGAFRTILDTAWI--SLTALGLAPGA 68
Query: 246 LKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 425
+ ++ + + DL AV GA F+QE PENL +K+ ++ L +V +N +
Sbjct: 69 --SLDRLRVVH---DLDAAVAGAGFIQESAPENLAMKQALYHRLGRIVPENVVIGSSTSG 123
Query: 426 XXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVS 605
+ + ++ HP NPPY +PLVEIV T P + E G+ P+
Sbjct: 124 LMMTDIQANCETPGRTVIGHPFNPPYLLPLVEIVGGERTDPAAVEWAGEFYRVAGKAPLM 183
Query: 606 LTREIDGFVLNRIQYAILDE 665
+ +EI GFV R+Q A+ E
Sbjct: 184 MKKEIPGFVATRLQEALWRE 203
>UniRef50_A0RUN1 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase; n=4; Crenarchaeota|Rep: 3-hydroxyacyl-CoA
dehydrogenase/enoyl-CoA hydratase - Cenarchaeum
symbiosum
Length = 365
Score = 96.7 bits (230), Expect = 5e-19
Identities = 53/189 (28%), Positives = 92/189 (48%)
Frame = +3
Query: 99 IGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKASEQFQCIK 278
+G A + A+ GY+V + D+ + + A+E I++ L + + G + E K I+
Sbjct: 1 MGHGIAQVSAASGYEVVLRDIEQRFLDSAMEKIRWSLDKMASKGRITAEEKDGI-LNRIR 59
Query: 279 GSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXXEGLK 458
L A++GA V E VPE +DLK+KV+ LD+ + +
Sbjct: 60 PVVALGEALEGADLVIEAVPEVMDLKRKVYAELDAAAPEGAAFASNTSTLPITEIAQATS 119
Query: 459 HKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLN 638
+ I H NPP + LVE++P T E + T E +E +G+Q V +++ GF++N
Sbjct: 120 RPERFIGIHFFNPPQLMKLVEVIPGEGTSDETTRMTLEYVESLGKQAVLCRKDVPGFIVN 179
Query: 639 RIQYAILDE 665
R+ ++ E
Sbjct: 180 RLFIPMVHE 188
>UniRef50_UPI00015BAF7B Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Ignicoccus hospitalis KIN4/I|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Ignicoccus hospitalis KIN4/I
Length = 683
Score = 96.3 bits (229), Expect = 7e-19
Identities = 60/203 (29%), Positives = 99/203 (48%), Gaps = 5/203 (2%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 251
K+ +VG+G++G A + A G V + D+ + + A+E IK L L G L+ +
Sbjct: 25 KVLVVGAGVMGHGIAQVAAMSGLNVRMIDIKQEFLDRAMERIKESLEKLYAKGKLKEPPE 84
Query: 252 -ASEQFQCIKGSTD----LATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXX 416
++ + + + D A A K FV E VPE L+LK+ VF LD + I
Sbjct: 85 EVLKRIETMVANPDDESSYAEAAKDVDFVIEAVPEKLELKRAVFSVLDKYAPPHAILASN 144
Query: 417 XXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQ 596
+ K +V+ H NPP + LVE+V T E K T E+ +++G+
Sbjct: 145 TSSIPITEIAKATKRPDKVVGMHFFNPPVILKLVEVVRGKETSDETVKITVELAKKMGKV 204
Query: 597 PVSLTREIDGFVLNRIQYAILDE 665
P+ + +++ GF++NRI L+E
Sbjct: 205 PIVVNKDVPGFIVNRIMARFLNE 227
>UniRef50_Q8XI27 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase
NAD-dependent; n=9; Clostridiales|Rep:
Beta-hydroxybutyryl-CoA dehydrogenase NAD-dependent -
Clostridium perfringens
Length = 282
Score = 94.7 bits (225), Expect = 2e-18
Identities = 60/199 (30%), Positives = 95/199 (47%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
EKI ++G+G +G FA GY+V V D+ + + I I L L + G + E
Sbjct: 2 EKIFVIGAGTMGAGIVQAFAQKGYEVIVRDIKDEFVDRGIAGINKGLTKLVSKGKITEED 61
Query: 249 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 428
K + + I G+TDL A + ++ V EN+++KK++F LD + + TI
Sbjct: 62 KEAVLSK-ITGTTDLGLAADCDLVIEAAV-ENMEIKKQIFAELDKICKEETILASNTSSL 119
Query: 429 XXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
+VI H NP + LVE++ T E K + + E IG+ PV +
Sbjct: 120 SITEVASATNRPDRVIGMHFFNPATIMKLVEVIRGMATSQETFDKVKAMSEAIGKTPVEV 179
Query: 609 TREIDGFVLNRIQYAILDE 665
E GFV+NRI +++E
Sbjct: 180 A-EAPGFVVNRILIPMINE 197
>UniRef50_A4FKS0 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Actinomycetales|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Saccharopolyspora erythraea
(strain NRRL 23338)
Length = 303
Score = 94.3 bits (224), Expect = 3e-18
Identities = 64/204 (31%), Positives = 98/204 (48%), Gaps = 5/204 (2%)
Frame = +3
Query: 81 IVGSGLIGRSWAMLFASVGYQVTVYDV---VAKQITDAIEDIKYQLHTLENDGLLRGELK 251
+VG+G IG WA LF++ G +V + D +A + DA+ + + + D LL G
Sbjct: 1 MVGAGTIGLGWAALFSAHGLEVRITDPRDDLASVVGDAMPLLAESMGR-DPDQLLAG--- 56
Query: 252 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 431
I+ + LA AV A VQE PE L+ K+ +F ++ +
Sbjct: 57 -------IEIADSLADAVSDADLVQENGPERLEFKQDLFADIARHAPPRAVLASSSSGIV 109
Query: 432 XXXXXEGLKHK--SQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVS 605
E L +++++HP NPP VPLVEIVP T+ V + +G+ PV
Sbjct: 110 ASAIAEHLPDDVAGRLLIAHPFNPPQVVPLVEIVPGERTEERVTEAATAFYTALGKTPVR 169
Query: 606 LTREIDGFVLNRIQYAILDEVWRL 677
L +E+ GFV NR+Q A++ E L
Sbjct: 170 LRKEVPGFVANRLQSAVMREATHL 193
>UniRef50_A3M445 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=1; Acinetobacter baumannii ATCC 17978|Rep: Putative
3-hydroxyacyl-CoA dehydrogenase - Acinetobacter
baumannii (strain ATCC 17978 / NCDC KC 755)
Length = 233
Score = 94.3 bits (224), Expect = 3e-18
Identities = 41/120 (34%), Positives = 65/120 (54%)
Frame = +3
Query: 318 FVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXXEGLKHKSQVIVSHPVNP 497
F+QE PE LDLK+ ++Q + S + T+ + H ++ + HP NP
Sbjct: 6 FIQENAPERLDLKQNLYQEITSYCPEKTLIASSSSGLKVSDFQKDATHPERIFLGHPFNP 65
Query: 498 PYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRL 677
P+ +PLVEIV T P++ KK E + +G+ P+ L +E+ G V NR+Q A+ E + L
Sbjct: 66 PHLLPLVEIVGGKLTDPQILKKASEFYQSLGKHPIVLNKEVKGHVANRLQAALWREAFSL 125
>UniRef50_Q5L0D2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Geobacillus kaustophilus
Length = 281
Score = 93.9 bits (223), Expect = 4e-18
Identities = 63/204 (30%), Positives = 92/204 (45%)
Frame = +3
Query: 66 SEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGE 245
+E I ++G+G++G A A VG V +YDV + + + + L G L E
Sbjct: 2 AETIAVIGAGVMGSGIAQTAAMVGKTVYLYDVSEAALQNGLASAEKSLRRFVKTGGL-SE 60
Query: 246 LKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 425
+A I+ + DLA AV+GA V E VPENL LKK VFQ LD + + I
Sbjct: 61 PEARAALGRIRSTVDLAEAVRGADVVIEAVPENLALKKDVFQQLDQLAKPDAILATNTSE 120
Query: 426 XXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVS 605
VI H NP + L+EIV T + R + E+G++ V
Sbjct: 121 LSVTALAAATNRPENVIGMHWFNPAPVMKLIEIVKGETTSDDTVDAIRRLSVELGKETV- 179
Query: 606 LTREIDGFVLNRIQYAILDEVWRL 677
+ ++ GFV R A + E R+
Sbjct: 180 VVKDRQGFVTTRALAAHMIECIRM 203
>UniRef50_Q9HKW7 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenase;
n=2; Thermoplasmatales|Rep: Probable 3-hydroxyacyl-CoA
dehydrogenase - Thermoplasma acidophilum
Length = 291
Score = 93.1 bits (221), Expect = 6e-18
Identities = 61/190 (32%), Positives = 92/190 (48%), Gaps = 3/190 (1%)
Frame = +3
Query: 81 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIK---YQLHTLENDGLLRGELK 251
+VGSG++G+ A +FA GY VT+ DV + +A+ IK Y L L G + E +
Sbjct: 8 VVGSGVMGQGIAQVFARSGYPVTIIDVRDDILANAVRSIKEGRYGLMNLVKKGTMT-ESE 66
Query: 252 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 431
+ I+ ST + + A V E VPENLDLK+KVF +++ V +N I
Sbjct: 67 VDKIMGKIRTSTSYGS-LSDADIVVEAVPENLDLKRKVFIDIEKNVSENAIIASNTSGIT 125
Query: 432 XXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLT 611
+ LK K + I H NP + L+E+V A T + + IG+ PV +
Sbjct: 126 IAEIAQDLKKKDRAIGMHWFNPAGIMKLIEVVRAKMTSEDTISTVVDFSRRIGKTPV-VV 184
Query: 612 REIDGFVLNR 641
++ GF R
Sbjct: 185 ADVPGFFTTR 194
>UniRef50_A6CP14 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Bacillus sp. SG-1|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Bacillus sp. SG-1
Length = 293
Score = 92.3 bits (219), Expect = 1e-17
Identities = 60/204 (29%), Positives = 99/204 (48%), Gaps = 3/204 (1%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
+K+ ++GSG++GR A + A G+Q T+ DV +Q+ A + +L ++ G+ RG+L
Sbjct: 13 DKLVVIGSGVMGRGIAYVSAVGGFQTTLVDVEQRQLDSA----QGELTSIFQKGVDRGKL 68
Query: 249 KASEQFQC---IKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXX 419
E + STD+A AV+ A V E VPE ++KK VF+ +D ++
Sbjct: 69 SKEESTDAQGRLSFSTDMAKAVESADLVIEAVPEKTEIKKAVFEKIDEYAQESCYFATNT 128
Query: 420 XXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQP 599
+VI H NP + +PLVEIV T E + + +G++
Sbjct: 129 STMSPTEIASFTGRPKKVIAMHFFNPVHKMPLVEIVRGLETSDETTQFAENAAKRMGKET 188
Query: 600 VSLTREIDGFVLNRIQYAILDEVW 671
V + E GFV +RI + +E +
Sbjct: 189 V-VINEFPGFVTSRISALVGNEAF 211
>UniRef50_Q5V0V6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Halobacteriaceae|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Haloarcula marismortui (Halobacterium marismortui)
Length = 654
Score = 92.3 bits (219), Expect = 1e-17
Identities = 50/197 (25%), Positives = 94/197 (47%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
+ ++G+G +G A + A GY V + D+ A + D ++I++ L L G L +
Sbjct: 11 VAVLGAGTMGHGIAEVAAIAGYDVVLRDIDAAIVEDGYDEIEWSLEKLAEKGRLDED--P 68
Query: 255 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 434
+ + +TDL AV A V E PE L +K+ +F+++D+ + +
Sbjct: 69 DDVAARVATTTDLEAAVSDADLVIEAGPEQLSVKQDIFESVDAAAPADALLATNSSSLSI 128
Query: 435 XXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTR 614
+ V+ H NPP + LVE++ T E A++ E +E +G+ P+ + +
Sbjct: 129 TEIAAATERPESVLGLHFFNPPVKMDLVEVIYGKATTDETAQRGYEFIESLGKTPIYVRK 188
Query: 615 EIDGFVLNRIQYAILDE 665
++ GFV+N + + E
Sbjct: 189 DVRGFVVNSVLGPFMSE 205
>UniRef50_Q7WCB1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4;
Bordetella|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Bordetella parapertussis
Length = 354
Score = 91.5 bits (217), Expect = 2e-17
Identities = 57/199 (28%), Positives = 95/199 (47%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
+ + +VG+G +G A LFAS G+ V + D +A +T A + I+ QL D +
Sbjct: 50 QNLAVVGAGAMGSGIAALFASKGFDVVLIDPMAGALTRAAQVIERQLGVYAPDAI----- 104
Query: 249 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 428
+ Q I+ L A A V E VPE L LK+ +F LD++ D I
Sbjct: 105 --APAMQRIRMDAGLEAACS-AQLVIEAVPEKLALKRDIFARLDTLCDPQAIFATNTSGL 161
Query: 429 XXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
+ + + + + +H P +PLVE+V T + + ++ G++PV +
Sbjct: 162 SINDIAQAVTRRDRFVGTHFFTPADVIPLVEVVRNDDTSEQTVARVMGMLRAGGKRPVLV 221
Query: 609 TREIDGFVLNRIQYAILDE 665
++I GF+ NRIQ+A+ E
Sbjct: 222 RKDIPGFIANRIQHALARE 240
>UniRef50_Q7D836 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=8; Mycobacterium tuberculosis complex|Rep:
3-hydroxyacyl-CoA dehydrogenase family protein -
Mycobacterium tuberculosis
Length = 304
Score = 91.5 bits (217), Expect = 2e-17
Identities = 60/198 (30%), Positives = 102/198 (51%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 251
+ +VG+GL+GR A + AS G V + D A+ + A + G RG +
Sbjct: 9 RAAVVGAGLMGRRIAGVLASAGLDVAITDTNAEILHAA------AVEAARVAGAGRGSVA 62
Query: 252 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 431
A + DLA A+ A V E V ENL +K+++F+ L ++ D +
Sbjct: 63 A---------AADLAAAIPDADLVIEAVVENLAVKQELFERLATLAPD-AVLATNTSVLP 112
Query: 432 XXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLT 611
E ++ S+VI +H NPP +P+VE+VP+ T P+ A + ++ ++G+ PV +
Sbjct: 113 IGAVTERVEDGSRVIGTHFWNPPDLIPVVEVVPSARTAPDTADRVVALLTQVGKLPVRVG 172
Query: 612 REIDGFVLNRIQYAILDE 665
R++ GF+ NR+Q+A+ E
Sbjct: 173 RDVPGFIGNRLQHALWRE 190
>UniRef50_Q2B4D1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Firmicutes|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Bacillus sp. NRRL B-14911
Length = 295
Score = 91.5 bits (217), Expect = 2e-17
Identities = 58/203 (28%), Positives = 95/203 (46%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
+ I +VG+G +G AML A G++ T++D+ K + A E ++ + G L E
Sbjct: 8 KNITVVGAGQMGHQIAMLCALGGFETTLHDMQEKALDQAQEKLRGIMDKWAAKGKLPSE- 66
Query: 249 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 428
+ F ++ ++D AVK A F+ E V E L++K++VF L+ + + I
Sbjct: 67 QIEAAFSRLRCTSDFGEAVKSADFIIEAVVEKLEVKREVFSMLEEMAPPHAIFATNSSTI 126
Query: 429 XXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
+ + H PP + VE+V + T E A+ E+ I + V L
Sbjct: 127 VNSLLANAADRPEKTVNMHFFFPPLVMDCVEVVMSSRTSEETAETAMEVCNAINRTAVLL 186
Query: 609 TREIDGFVLNRIQYAILDEVWRL 677
+EI GFV NRI A+ E +L
Sbjct: 187 KKEISGFVANRILGALQREAVQL 209
>UniRef50_Q4J0Z7 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
C-terminal:3-hydroxyacyl-CoA dehydrogenase, NAD binding
domain; n=2; Gammaproteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, C-terminal:3-hydroxyacyl-CoA
dehydrogenase, NAD binding domain - Azotobacter
vinelandii AvOP
Length = 307
Score = 91.1 bits (216), Expect = 3e-17
Identities = 55/197 (27%), Positives = 98/197 (49%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
I I+G+GL+G A A G+ V + D A+++ + L L + G +
Sbjct: 6 IVILGAGLMGIGIATHLARHGHAVLLRDPAAERLAEVPVMAGSILAELADAGRFE-RAQT 64
Query: 255 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 434
+ S LA + + E +PE L+LK+ ++ L+++V T+
Sbjct: 65 DATLARLAVSPRLADVADARLLI-EAIPERLELKRALYAELEALVGTGTVIASNTSGLPP 123
Query: 435 XXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTR 614
EG++H +++++H NPP+ +PLVEIVP T+ E + R ++ + + V L +
Sbjct: 124 DALAEGMRHPERLLIAHFWNPPHLIPLVEIVPGSATRAEHLEAVRTLLAGMELEAVVLDK 183
Query: 615 EIDGFVLNRIQYAILDE 665
I GF+ NR+Q+A+L E
Sbjct: 184 AIPGFIGNRLQFAVLRE 200
>UniRef50_Q0LRY2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=2; Alphaproteobacteria|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Caulobacter sp. K31
Length = 348
Score = 90.6 bits (215), Expect = 3e-17
Identities = 58/203 (28%), Positives = 97/203 (47%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
+ + ++G+GL+G A +FA+ GY V ++D T A I G +
Sbjct: 47 QPVAVLGAGLMGAGIAKVFAAKGYPVFLFDRDLDTATSATRQIN-------------GAI 93
Query: 249 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 428
+ + + + LA AV A FV E V E LD+K+++F L + +
Sbjct: 94 AHVDGGRDVDAAGSLAEAVADAAFVFESVSEKLDVKRRIFSALAECARHDAVLASNTSAI 153
Query: 429 XXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
EGL +++++ SH NP VPLVE+VP T + +++ +G++ V +
Sbjct: 154 PITQIAEGLPCEARIVGSHWWNPADVVPLVEVVPGIATDAHHVEAMMQLLISVGKKAVRI 213
Query: 609 TREIDGFVLNRIQYAILDEVWRL 677
R+I GFV NR+Q+A+ E L
Sbjct: 214 DRDIPGFVGNRLQFALWREAQSL 236
>UniRef50_Q9YBW6 Cluster: 3-hydroxyacyl-CoA
dehydrogenase/3-hydroxybutyryl-CoA dehydratase; n=19;
cellular organisms|Rep: 3-hydroxyacyl-CoA
dehydrogenase/3-hydroxybutyryl-CoA dehydratase -
Aeropyrum pernix
Length = 669
Score = 90.2 bits (214), Expect = 4e-17
Identities = 57/206 (27%), Positives = 102/206 (49%), Gaps = 7/206 (3%)
Frame = +3
Query: 48 MASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLEND 227
MA + K+ I +VG+G +G A L A G++V + D+ + +A++ I++ L L
Sbjct: 1 MAGEVKT--ITVVGAGTMGHGIAELAAIAGFKVYLADINIDILNNALQRIRWSLEKLAEK 58
Query: 228 GLLRGELKA--SEQFQCI-----KGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSV 386
G +R ++ S + + S DLA A+ + F+ E +PE L+LK+++F D
Sbjct: 59 GRIRESVETVMSRITPIVSVRDGEYSEDLAKALSESDFMIEAIPEKLELKQQLFAFADKH 118
Query: 387 VDDNTIXXXXXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKT 566
+ I +V+ H NPP +PLVE+V T E T
Sbjct: 119 AKETAILASNTSSLPITEIAAATSRPEKVVGMHFFNPPVLMPLVEVVKGEKTSEETVAAT 178
Query: 567 REIMEEIGQQPVSLTREIDGFVLNRI 644
++ +++G+Q V + +++ GF++NRI
Sbjct: 179 VDLAKKMGKQTVVVKKDVPGFIVNRI 204
>UniRef50_Q5HKI5 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=3; Staphylococcus|Rep: 3-hydroxyacyl-CoA
dehydrogenase family protein - Staphylococcus
epidermidis (strain ATCC 35984 / RP62A)
Length = 321
Score = 89.8 bits (213), Expect = 6e-17
Identities = 55/198 (27%), Positives = 85/198 (42%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 251
K +VG+G+IG W + G++V D + +K E GL
Sbjct: 2 KFAVVGTGVIGSGWITRMLAHGHEVIATDPSEGAYERMLTQVKQNWPYAEQMGLAE---- 57
Query: 252 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 431
+ Q + + L AVK A +QE VPE ++K V + +D
Sbjct: 58 -NASIQNLTFTPHLEEAVKDADHIQENVPEVEEIKDAVLKEIDFYAKPEATIGSSTSGIM 116
Query: 432 XXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLT 611
L H +++V+HP +P Y +PLVEIVP T E K +I E IG + +
Sbjct: 117 PSELQANLSHPERLVVAHPFHPVYILPLVEIVPGKQTSEETTVKAEQIYESIGMDVLHVR 176
Query: 612 REIDGFVLNRIQYAILDE 665
EI+G + +R+ A+ E
Sbjct: 177 HEIEGHIADRLMEALWRE 194
>UniRef50_O30218 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 661
Score = 89.4 bits (212), Expect = 8e-17
Identities = 54/197 (27%), Positives = 92/197 (46%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
+ ++G+G +G + A + A G+ V + DV Q+ A+E I+ L G + +
Sbjct: 9 VAVIGAGSMGHAIAEVVAIHGFNVKLMDVSEDQLKRAMEKIEEGLRKSYERGYISED--P 66
Query: 255 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 434
+ + I+ + DL K A V E +PE DLKKKVF ++ D+TI
Sbjct: 67 EKVLKRIEATADLIEVAKDADLVIEAIPEIFDLKKKVFSEIEQYCPDHTIFATNTSSLSI 126
Query: 435 XXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTR 614
E K + I H NPP + L+EIV T E + + +I + + + +
Sbjct: 127 TKLAEATKRPEKFIGMHFFNPPKILKLLEIVWGEKTSEETIRIVEDFARKIDRIIIHVRK 186
Query: 615 EIDGFVLNRIQYAILDE 665
++ GF++NRI + +E
Sbjct: 187 DVPGFIVNRIFVTMSNE 203
>UniRef50_Q46MP3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4;
Burkholderiales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Ralstonia eutropha (strain JMP134) (Alcaligenes
eutrophus)
Length = 304
Score = 89.0 bits (211), Expect = 1e-16
Identities = 56/198 (28%), Positives = 104/198 (52%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 251
++ ++G+GL+G A+ F + + V ++D V+ Q +A+ + + H LE L G+ +
Sbjct: 10 RVAVLGAGLMGHGIALAFMTSDFDVAIWDPVS-QAREAVRE-RIAEH-LE----LMGDPR 62
Query: 252 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 431
+ C + L V+ V E PE++ K+++ + +D +V+ I
Sbjct: 63 GVDVRVC----STLQDCVRDCDIVVEAAPESVSTKRELIREID-LVNSECIIASNTSVLR 117
Query: 432 XXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLT 611
EG +V+ +H NPPY +PLVE+V T+ VAK+ + + + G+ PV +
Sbjct: 118 ITEIAEGSADPGRVVGTHWWNPPYLMPLVEVVRGELTREGVAKQVSQWLSKAGKTPVDVY 177
Query: 612 REIDGFVLNRIQYAILDE 665
R++ GFV NR+Q+A++ E
Sbjct: 178 RDVPGFVGNRMQFALVRE 195
>UniRef50_A1SPQ6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3;
Actinomycetales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Nocardioides sp. (strain BAA-499 / JS614)
Length = 287
Score = 88.6 bits (210), Expect = 1e-16
Identities = 57/200 (28%), Positives = 93/200 (46%), Gaps = 1/200 (0%)
Frame = +3
Query: 81 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQL-HTLENDGLLRGELKAS 257
+VG+G +G AM+ A G+QV ++DV + A +++ ++ +E ++ A+
Sbjct: 6 VVGAGAMGSQIAMVCALAGHQVCLHDVDPAMLERADRELRDRMARQVEKGRRTADDVTAA 65
Query: 258 EQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXX 437
+ + S A A A V E V E +++K ++F LD + TI
Sbjct: 66 FERLRVADSLAAAAAAADADLVIEAVVERIEVKSELFAELDRLCPPATILASNSSSFVPS 125
Query: 438 XXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTRE 617
+V H NP + VE+VP P T + +++E +G+ PV L +E
Sbjct: 126 RLAAATGRADRVCNLHFFNPALVMACVEVVPGPETSGQTVASCVDLVESLGKVPVVLEKE 185
Query: 618 IDGFVLNRIQYAILDEVWRL 677
I GFV NRI A+ DE RL
Sbjct: 186 IPGFVANRILNAVRDEAIRL 205
>UniRef50_Q2UUZ5 Cluster: RIB40 genomic DNA, SC009; n=4;
Trichocomaceae|Rep: RIB40 genomic DNA, SC009 -
Aspergillus oryzae
Length = 337
Score = 88.2 bits (209), Expect = 2e-16
Identities = 62/215 (28%), Positives = 94/215 (43%), Gaps = 14/215 (6%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRG-ELK 251
+ I+G+G+IG SW LF + G +V V D + + Q TL GL G LK
Sbjct: 12 VAIIGTGVIGASWTALFLARGLKVLVTDPAPNAEKNLETYLNAQWPTLTQIGLSEGASLK 71
Query: 252 ASEQFQCIKGSTDLATAVKGAVF-----------VQECVPENLDLKKKVFQNLDSVVDDN 398
+ + ++ F V + PE L+ K+ +F LD
Sbjct: 72 NYAFVDSLDNHFEEIDFIQEVPFPFSNTGVILLTVTKNGPERLEFKRTLFAYLDEKARPE 131
Query: 399 TIXXXXXXXXXXXXXXEGLKHKSQ-VIVSHPVNPPYYVPLVEIVPAPWTKPE-VAKKTRE 572
I +H + V+V HP NPP+ +PLVE+VP T E V + E
Sbjct: 132 VIIASSSSGIPSSEYASACRHHPERVLVGHPFNPPHLIPLVEVVPHRTTDRETVVPRAME 191
Query: 573 IMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRL 677
+G++PV + +EI GF+ NR+Q A+ E + L
Sbjct: 192 FYRSLGKKPVLIQKEIPGFIANRLQAALSMEAYSL 226
>UniRef50_P76083 Cluster: Probable 3-hydroxybutyryl-CoA
dehydrogenase; n=8; Enterobacteriaceae|Rep: Probable
3-hydroxybutyryl-CoA dehydrogenase - Escherichia coli
(strain K12)
Length = 475
Score = 88.2 bits (209), Expect = 2e-16
Identities = 59/202 (29%), Positives = 94/202 (46%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
+ + ++GSG +G A + AS G+QV +YD+ A+ +T AI+ I +L++ G L E
Sbjct: 6 QTVAVIGSGTMGAGIAEVAASHGHQVLLYDISAEALTRAIDGIHARLNSRVTRGKLTAET 65
Query: 249 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 428
+ + TD+ A+ A V E E L++KK +F L V T+
Sbjct: 66 -CERTLKRLIPVTDIH-ALAAADLVIEAASERLEVKKALFAQLAEVCPPQTLLTTNTSSI 123
Query: 429 XXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
+K+ +V H NP + LVE+V T EV ++ E+ G+QPV
Sbjct: 124 SITAIAAEIKNPERVAGLHFFNPAPVMKLVEVVSGLATAAEVVEQLCELTLSWGKQPVR- 182
Query: 609 TREIDGFVLNRIQYAILDEVWR 674
GF++NR+ E WR
Sbjct: 183 CHSTPGFIVNRVARPYYSEAWR 204
>UniRef50_Q89HA7 Cluster: Blr6087 protein; n=6; Proteobacteria|Rep:
Blr6087 protein - Bradyrhizobium japonicum
Length = 330
Score = 87.4 bits (207), Expect = 3e-16
Identities = 60/209 (28%), Positives = 102/209 (48%), Gaps = 8/209 (3%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDV-------VAKQITDAIEDIKYQLHTLENDGL 233
I +G+G +GR A+ FA G++VT+ DV AK TDA+ +++ +L N GL
Sbjct: 7 IACLGAGRMGRGIAVAFAYAGHRVTMIDVKPRSAEDFAKLETDALGEVRKTFASLSNLGL 66
Query: 234 L-RGELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXX 410
L ++ + ++ TA+ A V E VPE ++LK++V V +TI
Sbjct: 67 LTEADVDPLVARVSVATASQSGTALADAGMVFEGVPEVVELKREVLGAASRQVKPDTIIA 126
Query: 411 XXXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIG 590
+ + + + H +NP Y +PLVE+ P T P + + + ++E IG
Sbjct: 127 STTSTILVDDLSGAIVNPHRFLNVHWLNPAYLIPLVEVSPGKATDPAIIDEVKALLEGIG 186
Query: 591 QQPVSLTREIDGFVLNRIQYAILDEVWRL 677
+ PV + GF++ RIQ ++E R+
Sbjct: 187 KVPV-VCAATPGFIVPRIQALAMNEAARM 214
>UniRef50_Q0FUM2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Rhodobacterales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Roseovarius sp. HTCC2601
Length = 220
Score = 87.4 bits (207), Expect = 3e-16
Identities = 55/204 (26%), Positives = 100/204 (49%)
Frame = +3
Query: 66 SEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGE 245
S +I +VG+G +G A L+A GY + D + +E + L D
Sbjct: 13 SGRICVVGAGFMGCVIATLYAHHGYDAVICDSNQTMLDTYVERARPIAAGLVEDSDASEA 72
Query: 246 LKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 425
+ A + DLA+A++G V E V E+L++K+ +F L+ + +N +
Sbjct: 73 MLAGVTLE-----PDLASAIEGVFLVHEAVQESLEVKQALFAELERICPENVVLATNTSS 127
Query: 426 XXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVS 605
+ K +++ H V P + VP++E++ A T E+ +R +++ I V+
Sbjct: 128 FLISDIAAQMTRKERMMGIHYVTPGHIVPVIELIHAADTPAELVAWSRMLVQNIEHVGVA 187
Query: 606 LTREIDGFVLNRIQYAILDEVWRL 677
+ E GF++NRIQ+A+L E++RL
Sbjct: 188 IL-ERPGFLVNRIQFAMLTEIYRL 210
>UniRef50_Q11E57 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=1; Mesorhizobium sp. BNC1|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Mesorhizobium sp. (strain BNC1)
Length = 485
Score = 87.0 bits (206), Expect = 4e-16
Identities = 57/201 (28%), Positives = 96/201 (47%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
IG++G+G +G A + A+ G++V ++DV + +E +L TL G + + +A
Sbjct: 11 IGVIGAGTMGAGIAQVAAAAGHKVLLFDVASGAAASGLERTAKELATLVKRGKME-QKRA 69
Query: 255 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 434
E I + L A+ V E + E LD+K+KVF L++++ ++ I
Sbjct: 70 EEIIGRITIAEKLEDLAPAALTV-EAIVERLDVKQKVFAQLEAILAEDAILATNTSSISI 128
Query: 435 XXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTR 614
LK +++ H NP + LVE+V T PEVA+ T G+ V + +
Sbjct: 129 TAIGAALKRPERLVGMHFFNPAPIMKLVEVVSGLATSPEVAQITHATARAWGKTAVHV-K 187
Query: 615 EIDGFVLNRIQYAILDEVWRL 677
GF++NR+ A E RL
Sbjct: 188 STPGFIVNRVARAFYGEPLRL 208
>UniRef50_A3STE1 Cluster: Putative hydroxlacyl-CoA dehydrogenase;
n=3; Rhodobacteraceae|Rep: Putative hydroxlacyl-CoA
dehydrogenase - Sulfitobacter sp. NAS-14.1
Length = 309
Score = 86.6 bits (205), Expect = 5e-16
Identities = 56/200 (28%), Positives = 88/200 (44%), Gaps = 3/200 (1%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDV---VAKQITDAIEDIKYQLHTLENDGLLRGE 245
+ ++G GLIG SWA LF G+ V +D + QL + +G
Sbjct: 7 VAVIGCGLIGASWAALFQHAGHTVRAWDPDTGARDGFAARVAGPLAQLQEISAGAAPQGA 66
Query: 246 LKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 425
L E Q A++ V +QE PEN+ LK +++ ++S+V + I
Sbjct: 67 LSTHESLQ---------DALQDVVLIQENAPENVPLKHQLYAQIESIVAPDVIIASSTSA 117
Query: 426 XXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVS 605
G++H ++I +HP NPP+ VPLVE+ P T V +G PV
Sbjct: 118 HPWSDLVPGMQHPDRLITAHPFNPPHLVPLVEVY-GPDT--NVLDWAEGFYRSLGSVPVR 174
Query: 606 LTREIDGFVLNRIQYAILDE 665
L ++ G + NR+ A+ E
Sbjct: 175 LKKDAVGHIANRLSSALWRE 194
>UniRef50_Q5V357 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
Halobacteriaceae|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Haloarcula marismortui (Halobacterium marismortui)
Length = 669
Score = 86.6 bits (205), Expect = 5e-16
Identities = 50/200 (25%), Positives = 94/200 (47%), Gaps = 1/200 (0%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTL-ENDGLLRGE 245
+ I ++G+G +G + A GY V + D+ + + D ++I++ L+ L E D L + E
Sbjct: 22 DTIAVLGAGNMGHGITEVAALAGYDVRMRDIKDEFVEDGYDNIEWSLNKLAERDQLTQEE 81
Query: 246 LKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 425
A+ + D+ AV V E VPE +++KK V+ ++ +N I
Sbjct: 82 ADAA--LDRVTPLVDVEEAVSDVDVVIEAVPEKMEIKKDVYTEVEEHAPENAIFATNTSS 139
Query: 426 XXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVS 605
E + Q H NPP + LVE++ + + + + E+ G+ PV
Sbjct: 140 LSITELSEVTERPEQFCGMHFFNPPVRMQLVEVISGAHSGDDTLEAIEALAEDFGKTPVR 199
Query: 606 LTREIDGFVLNRIQYAILDE 665
+ ++ GF++NRI +++E
Sbjct: 200 VRKDSPGFIVNRILVPLMNE 219
>UniRef50_A0LSM1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5;
Actinomycetales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Length = 301
Score = 85.8 bits (203), Expect = 1e-15
Identities = 58/202 (28%), Positives = 95/202 (47%), Gaps = 1/202 (0%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLR-GELK 251
+G+VGSGL+G A + A GY V ++D+ + A+ I LH L G L +++
Sbjct: 10 VGVVGSGLMGSGIAQVAAVAGYAVRLHDIEESALHRALTTIDESLHRLARKGKLSTSDVE 69
Query: 252 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 431
A++ I + LA V V E V E LD+K+ VF L ++V N +
Sbjct: 70 AAKAR--ITTTRRLADLADSDVVV-EAVYEELDVKRVVFAELAAIVRPNVLLASNTTAIP 126
Query: 432 XXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLT 611
G+ +V+ H +P + L EIV T + + R E +G+ + +
Sbjct: 127 ITHIASGVSGPQRVVGMHFFSPVPVMQLCEIVRGLQTDDDTVARARRFAESLGKTCIVVN 186
Query: 612 REIDGFVLNRIQYAILDEVWRL 677
R++ GFV +R+ A ++E RL
Sbjct: 187 RDVAGFVTSRLLVAFVNEALRL 208
>UniRef50_O29077 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
cellular organisms|Rep: 3-hydroxyacyl-CoA dehydrogenase
- Archaeoglobus fulgidus
Length = 295
Score = 85.8 bits (203), Expect = 1e-15
Identities = 63/204 (30%), Positives = 94/204 (46%), Gaps = 3/204 (1%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDV---VAKQITDAIEDIKYQLHTLENDGLLRGE 245
IG+VG+G++G A + A GY V + DV V K+ + IE + L L G + E
Sbjct: 9 IGVVGAGVMGHGIAQVAARTGYDVVMVDVSEEVLKKAMELIESGPFGLRRLVEKGKM-SE 67
Query: 246 LKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 425
+A I+ ST L A+K A F+ E V E DLKKK+F LD + TI
Sbjct: 68 DEAKAVMARIRTSTSLE-ALKDADFIIEAVTEKADLKKKIFAELDRICKPETIIASNTSA 126
Query: 426 XXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVS 605
++ K + I H NP + L+E++ T E T E+ +++G+ P+
Sbjct: 127 IMISDLATAVERKDKFIGMHWFNPAPVMRLIEVIRGALTSDETFNITVELSKKMGKIPIE 186
Query: 606 LTREIDGFVLNRIQYAILDEVWRL 677
+ GF R + L E RL
Sbjct: 187 -AGDGPGFFTTRFINSWLVEAVRL 209
>UniRef50_Q891F6 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxybutyryl-coA dehydrogenase -
Clostridium tetani
Length = 282
Score = 85.4 bits (202), Expect = 1e-15
Identities = 56/199 (28%), Positives = 96/199 (48%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
+KI ++G+G +G A FA+ GY+V + D+ + + I+ I+ L L + G + E
Sbjct: 2 KKICVLGAGTMGAGIAQAFAAKGYEVVLRDIKDEFVERGIKGIEKGLSKLVSKGRMAQED 61
Query: 249 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 428
S + I+G+ DL A + V+ + EN+++K+++F LD + TI
Sbjct: 62 MDSILGR-IEGTVDLNKAADCDLVVEAAI-ENMEIKREIFAELDRICKPETILSSNTSSL 119
Query: 429 XXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
+VI H NP + L+EI+ T E +E+ IG+ PV +
Sbjct: 120 SITEIATATNRPDKVIGMHFFNPAPVMKLIEIIRGMATSQETFDAVKEVSVAIGKDPVEV 179
Query: 609 TREIDGFVLNRIQYAILDE 665
E GFV+NRI +++E
Sbjct: 180 A-EAPGFVVNRILIPMINE 197
>UniRef50_Q28KL8 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=2; Bacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase NAD-binding - Jannaschia sp. (strain CCS1)
Length = 466
Score = 85.4 bits (202), Expect = 1e-15
Identities = 63/205 (30%), Positives = 97/205 (47%), Gaps = 4/205 (1%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDV---VAKQITDAIEDIKYQLHTLENDGLL-R 239
K I+G G+IG WA F G+ V +YD ++I + +++ + L L + L
Sbjct: 2 KTAIIGGGVIGGGWAARFLLNGWNVAIYDPDPEAERKIGEVMDNARRALPGLYDTALPPE 61
Query: 240 GELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXX 419
G L+ ++ DL AV A +VQE VPE LD+K KV L ++ +
Sbjct: 62 GTLRFTD---------DLGDAVGDADWVQESVPERLDIKHKVHAELTTLAPGRAVIGSST 112
Query: 420 XXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQP 599
E ++VIV+HP NP Y +PL+E+V + K EI+ IG P
Sbjct: 113 SGFKPSELTE---KGARVIVAHPFNPVYLLPLIELV----GDTDHCAKAAEILRGIGMYP 165
Query: 600 VSLTREIDGFVLNRIQYAILDEVWR 674
+ + +EID + +R L+ VWR
Sbjct: 166 LHVRKEIDAHIADR----FLEAVWR 186
>UniRef50_Q4J6T7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Archaea|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Sulfolobus acidocaldarius
Length = 657
Score = 85.4 bits (202), Expect = 1e-15
Identities = 53/192 (27%), Positives = 94/192 (48%), Gaps = 1/192 (0%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 251
++G+VG+G +G A + A G+ V + DV + +A+E I++ L L + ++K
Sbjct: 6 RVGVVGAGTMGHGIAEVVAIAGFNVVLTDVNEDILRNALEKIRWSLEKLRE----KRQIK 61
Query: 252 ASEQFQCIKGSTDLATAVKGAV-FVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 428
+ + T ++ V F+ E E D+K+K+F LD VV + I
Sbjct: 62 ENPNTVLSRIKTTVSFGDFSDVDFIIEAAIERSDVKRKIFSELDRVVKKDAIFATNTSTI 121
Query: 429 XXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
E + + I H +NPP +PLVEI+ T E K T ++ ++I + V +
Sbjct: 122 PISYLAEVTGRQEKFIGLHFMNPPVLMPLVEIIMGNKTAEETLKTTIDLAKKINKDYVVV 181
Query: 609 TREIDGFVLNRI 644
+++ GF++NRI
Sbjct: 182 KKDVPGFLINRI 193
>UniRef50_A1IEK7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Candidatus
Desulfococcus oleovorans Hxd3
Length = 387
Score = 85.0 bits (201), Expect = 2e-15
Identities = 54/192 (28%), Positives = 87/192 (45%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
+KI ++GSG +G A + GY V + DV + + + ++ +K + L G L E
Sbjct: 7 KKIAVIGSGAMGHGIAQVCIMAGYTVVMVDVKQEFLDNGMKKVKESMDFLVGKGKLSAED 66
Query: 249 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 428
K Q + S D AV V E VPE +DLKKKVF ++ S +
Sbjct: 67 KDRMMGQ-LSTSLDNKAAVADVQVVIEAVPEIMDLKKKVFADVSSAAPAEALLASNTSTM 125
Query: 429 XXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
+ + + H NP + LVE++ T E E+ ++IG+ PV +
Sbjct: 126 SITEIATAVTKPERFLGMHFFNPVNRMKLVEVIFGEKTSAENVDLLCELSKKIGKIPVKV 185
Query: 609 TREIDGFVLNRI 644
++ GF++NRI
Sbjct: 186 LKDSPGFIVNRI 197
>UniRef50_Q0RVG8 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 288
Score = 84.6 bits (200), Expect = 2e-15
Identities = 56/204 (27%), Positives = 99/204 (48%)
Frame = +3
Query: 66 SEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGE 245
+ +I + G+G++GR A++ A G++V++YD A D+ +
Sbjct: 3 ASQISVFGAGIMGRGIAVVLADAGHRVSLYDARA--------DVARE------------- 41
Query: 246 LKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 425
A+ I+ S + AV+G+ + E V ENL++K+ +F ++ ++T
Sbjct: 42 --AAAAHPNIEASDTIEAAVEGSSLLFEAVVENLEVKRDLFAEIERF-SESTPIASNTST 98
Query: 426 XXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVS 605
+ L +++++H NP VPLVE+VP+P T+P+V + G+ V
Sbjct: 99 FTPSELAKNLCEPGRLVIAHFFNPAEVVPLVEVVPSPDTRPDVVSAVTSALVAAGKTVVP 158
Query: 606 LTREIDGFVLNRIQYAILDEVWRL 677
L RE GFV NR+Q A++ E L
Sbjct: 159 LNREAPGFVANRLQAALVREAMAL 182
>UniRef50_A0JTB4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=5;
Actinomycetales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Arthrobacter sp. (strain FB24)
Length = 333
Score = 84.6 bits (200), Expect = 2e-15
Identities = 55/215 (25%), Positives = 100/215 (46%), Gaps = 1/215 (0%)
Frame = +3
Query: 36 STVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHT 215
+T ++ + KI +VGSG +G A + A G +V + DV A+ + + +
Sbjct: 9 TTAASSAANSARKIAVVGSGYMGGGIAQVLALGGARVALADVSAEVAQSNYDRLLAESDQ 68
Query: 216 LENDGLL-RGELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVD 392
DGL G + +Q + + D+ AV A F++E VPE + +K + + +
Sbjct: 69 FVADGLFPAGSTEILKQN--LWAARDIEEAVADADFIEEAVPEIIAIKHQTLARISAAAR 126
Query: 393 DNTIXXXXXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTRE 572
+ I E + + + + H NP ++P VEI+P T R+
Sbjct: 127 PDAIIGSNTSTISIADLSEPVTNPERFLGVHFSNPSPFIPGVEIIPHAGTSATTVGAVRD 186
Query: 573 IMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRL 677
++ G+Q ++ +++ GFVLNR+QYA+ E +L
Sbjct: 187 LVHAAGKQ-TAVVKDVTGFVLNRLQYALFHEAAQL 220
>UniRef50_Q9KBD3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=8;
Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Bacillus halodurans
Length = 287
Score = 83.8 bits (198), Expect = 4e-15
Identities = 52/193 (26%), Positives = 94/193 (48%), Gaps = 3/193 (1%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQ-LHTLENDGLLRGELK 251
+G+VG+G +G A L A G QV + D+ Q+ DI +Q ++T + +G++
Sbjct: 6 VGVVGAGTMGSGIANLAAMSGLQVVLLDLDDNQL-----DIAWQKINTFMEKSVAKGKMS 60
Query: 252 ASEQFQCIKG--STDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 425
+E+ + ST + A V E V ENLD+KK+VF LD+ + ++TI
Sbjct: 61 EAEKEAALGRIKSTTTYEELAEADLVIEAVIENLDVKKEVFHTLDTCLANDTIIATNTSS 120
Query: 426 XXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVS 605
+V+ H NP + LVE+V T + + ++ ++ ++P+
Sbjct: 121 MSITEIAAATNRPDRVVGMHFFNPAQLMKLVEVVRGYQTSDDTVETVKQFARQLKKEPIE 180
Query: 606 LTREIDGFVLNRI 644
+ ++ GF++NRI
Sbjct: 181 VKKDTPGFIVNRI 193
>UniRef50_Q397D0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=31;
Proteobacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 518
Score = 83.8 bits (198), Expect = 4e-15
Identities = 56/201 (27%), Positives = 91/201 (45%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
+G++G+G +G A + A+ G+ V +YD+ A+ I+ Q L G L +A
Sbjct: 20 VGVIGAGAMGAGIAQVAAAAGHTVLLYDLNEAACDKALAGIRAQFARLAEKGRLE-PAQA 78
Query: 255 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 434
I+ +LA GA + E E LD+K+++F L+ VDD +
Sbjct: 79 DAAGARIRAVRELADFA-GAALIVEAAAERLDVKREIFATLERHVDDACLLATNTSSISI 137
Query: 435 XXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTR 614
GL+ +V H NP + LVE+V T PEVA+ G++PV + +
Sbjct: 138 TSIAAGLRVPQRVAGLHFFNPAPLMALVEVVSGLATAPEVAQVLYATAAAWGKRPV-MAK 196
Query: 615 EIDGFVLNRIQYAILDEVWRL 677
GF++NR+ E R+
Sbjct: 197 STPGFIVNRVARPYYAEALRV 217
>UniRef50_Q0YNQ2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=3; Geobacter|Rep: 3-hydroxybutyryl-CoA
dehydrogenase precursor - Geobacter sp. FRC-32
Length = 289
Score = 83.8 bits (198), Expect = 4e-15
Identities = 58/201 (28%), Positives = 99/201 (49%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
+G+ G+G +G A + A G QV V D+ + A + I L + G + E +
Sbjct: 9 VGMAGAGSMGAGIAQIAAMAGLQVKVVDMSEEVWGRAKKTIVKSLERVVKKGTIT-EKEM 67
Query: 255 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 434
E I STD+A+ +K F+ E V E++++KK++F LD+V D+TI
Sbjct: 68 EETLGRISFSTDVAS-LKDVPFIFEAVFEDINVKKELFAKLDAVCGDDTIYATNTSSISI 126
Query: 435 XXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTR 614
+K+ + I H NP + LVE++PA T P E+ ++IG+ ++ +
Sbjct: 127 TEMAALVKNPANFIGMHFFNPVPVMKLVEVIPALQTAPATKDLALEMAKKIGKTAIT-CK 185
Query: 615 EIDGFVLNRIQYAILDEVWRL 677
+ GFV+NR+ + + RL
Sbjct: 186 DTPGFVVNRLFVPYIIDAVRL 206
>UniRef50_A5V325 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Sphingomonas wittichii RW1|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Sphingomonas wittichii RW1
Length = 322
Score = 83.8 bits (198), Expect = 4e-15
Identities = 53/201 (26%), Positives = 85/201 (42%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
+ +G G+IG W F G V ++D + + GL R +
Sbjct: 13 VAAIGGGVIGGGWVAAFLGSGRAVRLHDPAPGAEARIRAHVTQAWPQMAALGLARADDDW 72
Query: 255 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 434
+ + + D AV+G FVQE PE D+K+ +F LD +V + +
Sbjct: 73 TGRLSFHETIED---AVEGTDFVQENTPERSDVKRALFAELDRLVPADVLVGSSTSSLPI 129
Query: 435 XXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTR 614
GL ++ ++ HP NP + +PLVE+ T P +G++PV L R
Sbjct: 130 SDLQAGLSTAARFVLGHPFNPVHLIPLVEVGGGDATDPAAVDTALAFYAALGKEPVRLNR 189
Query: 615 EIDGFVLNRIQYAILDEVWRL 677
E+ G + NR+ A+ E RL
Sbjct: 190 EVFGHIGNRLTSAMFREAVRL 210
>UniRef50_Q5UWD9 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
cellular organisms|Rep: 3-hydroxyacyl-CoA dehydrogenase
- Haloarcula marismortui (Halobacterium marismortui)
Length = 295
Score = 83.8 bits (198), Expect = 4e-15
Identities = 58/204 (28%), Positives = 94/204 (46%), Gaps = 3/204 (1%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRG---E 245
+ I+G+G +G A + A G+ V++ D+ A + D + I+ L +G+ R E
Sbjct: 4 VAILGAGTMGHGIAQVSAMAGHDVSLRDIEADIVDDGLTAIESNLE----EGIAREKVTE 59
Query: 246 LKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 425
A +KG+T L AV GA V E VPE + +K + ++S VD T+
Sbjct: 60 STAEATIDRLKGTTSLEEAVTGADLVVEAVPEEMAIKHETLTAVESHVDPATLIASNTSS 119
Query: 426 XXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVS 605
L + + I H NP + + LVEIV A T E + RE + I + PV
Sbjct: 120 LSLTEIASVLDYPERAIGLHFFNPVHIMALVEIVVAEQTSAETIARAREFVNGIDKTPVE 179
Query: 606 LTREIDGFVLNRIQYAILDEVWRL 677
+ + GF +R+ ++ E R+
Sbjct: 180 VA-DAPGFASSRLGVSLGVEAMRM 202
>UniRef50_A4YDR4 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=2; Sulfolobaceae|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Metallosphaera sedula DSM 5348
Length = 334
Score = 83.4 bits (197), Expect = 5e-15
Identities = 50/195 (25%), Positives = 97/195 (49%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 251
K+ ++GSG++G +FA G++VT+YDV + + A+E I++ L L+ G ++
Sbjct: 2 KVFVIGSGVMGSGIGQVFAMAGHEVTLYDVKEEALKKAMEGIRWSLQKLQEKGSVK---D 58
Query: 252 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 431
I S DL+ A V E V E++ +K V + + D+ I
Sbjct: 59 VESVLSRIFTSRDLSEARDHLVI--EAVFEDIKVKSDVLGRVSPLTDE--IIASNTSSLP 114
Query: 432 XXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLT 611
+++ + + H NPP + LVE++ T E ++ +I++ +G+ P+ +
Sbjct: 115 ITELSRAVRNPERFLGMHFFNPPVLMKLVEVIRGDNTSEERFREALDIVKSLGKYPLPVR 174
Query: 612 REIDGFVLNRIQYAI 656
+++ GFV+NRI + +
Sbjct: 175 KDVFGFVVNRILFRL 189
>UniRef50_A4ALU9 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like
protein; n=1; marine actinobacterium PHSC20C1|Rep:
3-hydroxyacyl-CoA dehydrogenase-like protein - marine
actinobacterium PHSC20C1
Length = 288
Score = 82.6 bits (195), Expect = 9e-15
Identities = 58/206 (28%), Positives = 90/206 (43%), Gaps = 4/206 (1%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 251
K+ +VGSG +G L A G V V+DV + A + L + +R E
Sbjct: 5 KLAVVGSGTMGHGIGQLAAMQGIAVRVFDVDEVALDRARASVATSL-----ERFVRKETI 59
Query: 252 ASEQFQCIKG----STDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXX 419
Q I+G +TDL A+ G E VPE L LK+KVF +LD +
Sbjct: 60 TDAQSHEIQGRMDWTTDLDAALVGVEAAIEAVPEVLALKQKVFTDLDERTGPEVMLATNT 119
Query: 420 XXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQP 599
KH +V+ H NPP + LVEI+ T E+ ++ + +++G++
Sbjct: 120 SQLSITTIASSAKHPERVVGMHFFNPPVVMRLVEIIRGTMTSDEMLQRAIDFSDQLGKEN 179
Query: 600 VSLTREIDGFVLNRIQYAILDEVWRL 677
+ R+ GF+ R A+ E R+
Sbjct: 180 IVCQRDTPGFITTRAIMALRLECIRI 205
>UniRef50_A2TU34 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4;
Flavobacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Dokdonia donghaensis MED134
Length = 394
Score = 81.8 bits (193), Expect = 2e-14
Identities = 59/207 (28%), Positives = 100/207 (48%), Gaps = 4/207 (1%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
+ IGI+G+G +G A + A+ G V ++DV + + A E ++ L L + +G +
Sbjct: 3 KNIGIIGAGTMGSGIAQVAATAGCAVKLFDVNQEALDKAKEALEKVLKRL----IEKGRI 58
Query: 249 KASEQFQCIKGSTDLATAVK---GAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXX 419
ASE+ + I+ + T +K A E + ENL++KKKVFQ L++ V D I
Sbjct: 59 DASEKDR-IQANITYVTTLKELANADLTIEAIVENLEVKKKVFQELETYVSDTAIIASNT 117
Query: 420 XXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKK-TREIMEEIGQQ 596
L++ + I H NP + LVE++PA T V EI ++
Sbjct: 118 SSLSIASIAASLQNPERCIGIHFFNPAPLMKLVEVIPAVQTSQNVLDTCVAEITR--WKK 175
Query: 597 PVSLTREIDGFVLNRIQYAILDEVWRL 677
V++ ++ GF++NR+ E R+
Sbjct: 176 VVAIAKDTPGFIVNRVARPFYGEALRM 202
>UniRef50_Q16836 Cluster: Hydroxyacyl-coenzyme A dehydrogenase,
mitochondrial precursor; n=40; Eukaryota|Rep:
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial
precursor - Homo sapiens (Human)
Length = 314
Score = 81.8 bits (193), Expect = 2e-14
Identities = 58/230 (25%), Positives = 100/230 (43%), Gaps = 5/230 (2%)
Frame = +3
Query: 3 FTRGLSCGTVASTVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITD 182
F R +S + AS A K + + ++G GL+G A + A+ G+ V + D +
Sbjct: 8 FMRSVSSSSTASA--SAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAK 65
Query: 183 AIEDIKYQLHTLENDGLLRGELKASEQF-----QCIKGSTDLATAVKGAVFVQECVPENL 347
+ + I+ L + KA ++F I STD A+ V V E + ENL
Sbjct: 66 SKKGIEESLRKVAKKKFAENP-KAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENL 124
Query: 348 DLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIV 527
+K ++F+ LD ++TI + + H NP + LVE++
Sbjct: 125 KVKNELFKRLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVI 184
Query: 528 PAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRL 677
P T + + + + +G+ PVS ++ GF++NR+ L E RL
Sbjct: 185 KTPMTSQKTFESLVDFSKALGKHPVS-CKDTPGFIVNRLLVPYLMEAIRL 233
>UniRef50_Q9RZ10 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putative;
n=11; Bacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase,
putative - Deinococcus radiodurans
Length = 347
Score = 81.4 bits (192), Expect = 2e-14
Identities = 54/202 (26%), Positives = 86/202 (42%)
Frame = +3
Query: 54 SKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGL 233
S + + + GSG++G A A G+ V +YD+ I A E + +L L
Sbjct: 50 SSMSIKTVTVCGSGVLGSQIAFQTAFHGFDVHLYDINDAAIAKARETLG-KLQARYQQDL 108
Query: 234 LRGELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXX 413
+ + F I TD+A AVKG V E +PEN+D+K+K + L V D NTI
Sbjct: 109 KVDAQQTGDAFARISFFTDIAEAVKGVDLVIEAIPENMDIKRKFYNQLGEVADPNTIFAT 168
Query: 414 XXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQ 593
E + + H N + EI+ P T V + ++IG
Sbjct: 169 NSSTLLPSQFMEETGRPEKFLALHFANEIWKFNTAEIMRTPRTDDAVFDTVVQFAKDIGM 228
Query: 594 QPVSLTREIDGFVLNRIQYAIL 659
+ + +E G++LN + +L
Sbjct: 229 VALPMYKEQAGYILNTLLVPLL 250
>UniRef50_A2QXC7 Cluster: Contig An11c0270, complete genome.
precursor; n=6; Pezizomycotina|Rep: Contig An11c0270,
complete genome. precursor - Aspergillus niger
Length = 599
Score = 81.4 bits (192), Expect = 2e-14
Identities = 57/202 (28%), Positives = 92/202 (45%), Gaps = 1/202 (0%)
Frame = +3
Query: 66 SEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGE 245
S + ++G+G++GR A +FA+ GY V +YD A++ + L T
Sbjct: 12 SRPLALLGAGVLGRRIACVFAAAGYNVNLYDPSLSAQQAALDYVTQNLKTYSKFS----- 66
Query: 246 LKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 425
K + +F + +DL + V A V E VPE+L +K V LD + + I
Sbjct: 67 -KGNRRFGHCRAFSDLESTVSDAWLVIEAVPEHLQMKIDVMGELDKLAPVDCILASNSSS 125
Query: 426 XXXXXXXEGLK-HKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPV 602
E + H+ ++ + P +VE++ T PEV ++E++G PV
Sbjct: 126 FKSRFMLEKVGGHRRPLVCNMHFYMPPEKRVVELMTDGETWPEVFPFLTRVLEDVGMVPV 185
Query: 603 SLTREIDGFVLNRIQYAILDEV 668
+ RE GFV NR+ AI EV
Sbjct: 186 TARRESTGFVFNRLWAAIKREV 207
>UniRef50_Q0LZ25 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Caulobacter sp. K31|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Caulobacter sp. K31
Length = 296
Score = 80.6 bits (190), Expect = 4e-14
Identities = 64/214 (29%), Positives = 109/214 (50%), Gaps = 6/214 (2%)
Frame = +3
Query: 54 SKFKSE-KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDG 230
S F E KIG+VG+GL+G A++FA G V ++D A A+E +L L + G
Sbjct: 10 SPFAPELKIGVVGAGLMGAEIALVFALGGMDVLLHDRDAA----ALEKALARLSALLDRG 65
Query: 231 LLRG---ELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNT 401
+ RG E + + + I+ + DL+ V E V E+L++K +V LD +
Sbjct: 66 VSRGLYTEGRRATALENIRLAPDLSR-FGDRDLVTEAVFESLEVKGQVLAALDEACPEAC 124
Query: 402 IXXXXXXXXXXXXXXEGL--KHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREI 575
+ L + + + + +H +P + LVE+VPA T PE T +
Sbjct: 125 VIASNTSTLPISTLGAALSPERRPRFLGAHYFSPVSRMLLVEVVPAFETSPETVAWTTSL 184
Query: 576 MEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRL 677
++ IG+QP+++ +++ GF +NR+ +A+L E RL
Sbjct: 185 LKRIGKQPIAV-KDVPGFAVNRMLHAMLIEAVRL 217
>UniRef50_Q11TH9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=16;
Bacteroidetes|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)
Length = 298
Score = 80.2 bits (189), Expect = 5e-14
Identities = 57/195 (29%), Positives = 85/195 (43%)
Frame = +3
Query: 81 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKASE 260
I+GSG +G A FA G+QV + D A + A+ I L + G++ K +
Sbjct: 10 IIGSGTMGSGIAHSFAQFGFQVFLCDSNAAALNKAMLQISTNLERQISKGIIPDSEKETI 69
Query: 261 QFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXX 440
I TD A K V E VPE L++K +F+ LD TI
Sbjct: 70 -ISRITPITDFKEAAKTVSLVVEAVPELLEIKADLFKELDMHCPPETILASNTSSISITT 128
Query: 441 XXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREI 620
+VI H +NP + LVEI+ T E ++ EI ++ + PV T +
Sbjct: 129 LASYTSRPEKVIGMHFMNPVPVMQLVEIINGLLTSSETTRRIEEISTQLNKIPVQ-TADY 187
Query: 621 DGFVLNRIQYAILDE 665
GF+ NRI +++E
Sbjct: 188 PGFISNRILMPMINE 202
>UniRef50_A2QCM7 Cluster: Catalytic activity: precursor; n=5;
Trichocomaceae|Rep: Catalytic activity: precursor -
Aspergillus niger
Length = 338
Score = 80.2 bits (189), Expect = 5e-14
Identities = 44/127 (34%), Positives = 67/127 (52%), Gaps = 2/127 (1%)
Frame = +3
Query: 291 LATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXXEGLKHKSQ 470
L +A A VQE PEN+D K+ + +++V + ++ K++
Sbjct: 93 LESACASATIVQEQGPENVDWKQSAWARIEAVAPPSAHLWTSTSGIAASIQQAKMQDKTR 152
Query: 471 VIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIG--QQPVSLTREIDGFVLNRI 644
++V HP NPP +PL+EIVPAP T E + RE G +PV + +EI GFV NR+
Sbjct: 153 LLVVHPFNPPNIMPLLEIVPAPGTSAERVEFAREYFSLPGSRHRPVVIQKEIPGFVGNRL 212
Query: 645 QYAILDE 665
+A+L E
Sbjct: 213 AFALLRE 219
>UniRef50_A7D676 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Halorubrum lacusprofundi ATCC
49239|Rep: 3-hydroxyacyl-CoA dehydrogenase, NAD-binding
- Halorubrum lacusprofundi ATCC 49239
Length = 676
Score = 80.2 bits (189), Expect = 5e-14
Identities = 47/200 (23%), Positives = 91/200 (45%), Gaps = 1/200 (0%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTL-ENDGLLRGE 245
+++ ++G+G +G A + A GY V + D+ + + + I++ L L E D + GE
Sbjct: 20 QRVTVLGAGNMGHGIAEVAALAGYDVALRDIEEEFVQGGYDQIEWSLGKLAEKDRI--GE 77
Query: 246 LKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 425
+A ++ DL ++ A V E VPE + +KK V+ + + +
Sbjct: 78 DEADAALDRVEAFVDLEDSLADADVVVEVVPEKMAIKKDVYDEVVEYAPEEAVFVTNTSS 137
Query: 426 XXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVS 605
E + H NPP + LVE++ T + + + E +G+ PV
Sbjct: 138 LSITELSEVTDRPERFCGMHFFNPPVRMDLVEVISGKHTSEDTLELIEGLAESMGKTPVR 197
Query: 606 LTREIDGFVLNRIQYAILDE 665
+ ++ GF++NRI +++E
Sbjct: 198 VRKDSPGFIVNRILVPLMNE 217
>UniRef50_A0LPA1 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Syntrophobacter fumaroxidans MPOB|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
Length = 287
Score = 78.6 bits (185), Expect = 1e-13
Identities = 54/195 (27%), Positives = 88/195 (45%)
Frame = +3
Query: 81 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKASE 260
+VG+G +G A L A G++V + D+ + A I+ L G L K +
Sbjct: 8 VVGAGNMGAGIAQLCAQQGFEVVIADISLELSDKAKARIEKGLRKRVEQGKLDAAQKDAI 67
Query: 261 QFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXX 440
+ I+ + DL A FV E V E++ +K+KVF LD++ TI
Sbjct: 68 LSR-IQTAGDLGPAAV-CRFVIESVIEDIAIKRKVFAELDNLSPPETILATNTTSLSISA 125
Query: 441 XXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREI 620
E + +V+ H NPP + LVEI+P T E + E ++G+ PV E
Sbjct: 126 MAEATRRPERVVQMHFFNPPVIMKLVEIMPGKKTSRETVEAAAEFARQLGKDPVVCKNEA 185
Query: 621 DGFVLNRIQYAILDE 665
+++R+ +L+E
Sbjct: 186 PAGIVSRVLGQLLNE 200
>UniRef50_A6ERZ1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
unidentified eubacterium SCB49|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - unidentified eubacterium SCB49
Length = 403
Score = 78.2 bits (184), Expect = 2e-13
Identities = 54/203 (26%), Positives = 94/203 (46%), Gaps = 2/203 (0%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
IGI+G+G +G A + A+ G V ++D+ + A ++ + L G + E KA
Sbjct: 20 IGIIGAGTMGSGIAQVAATAGCTVKLFDLNQAALDKAKASLEKIMTRLVEKGRVTEEEKA 79
Query: 255 --SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 428
E + +LA + E + E+L +KKKVFQ L+S V D+ I
Sbjct: 80 RIQENISYVNALKELADSD----LTIEAIIEDLGIKKKVFQELESYVSDSCIIASNTSSL 135
Query: 429 XXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
L+ + + H NP + LVE++PA T V K + E ++ ++ V++
Sbjct: 136 SIASIASSLQKPERCVGIHFFNPAPLMKLVEVIPAIQTSDAVLKISEETIKS-WKKVVAV 194
Query: 609 TREIDGFVLNRIQYAILDEVWRL 677
++ GF++NR+ E R+
Sbjct: 195 AKDTPGFIVNRVARPFYGEALRI 217
>UniRef50_A1SSP5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Psychromonas ingrahamii 37|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Psychromonas ingrahamii (strain 37)
Length = 511
Score = 78.2 bits (184), Expect = 2e-13
Identities = 50/196 (25%), Positives = 94/196 (47%)
Frame = +3
Query: 57 KFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLL 236
K + + ++G+G +G A + A GYQV ++D+ + +A E+I+ QL G +
Sbjct: 3 KLLFKTVAVIGAGAMGAGIAQVAAQSGYQVYLFDLAKGKAEEAKENIEKQLERRVKKGRM 62
Query: 237 RGELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXX 416
+ S + I S++L+ + A V E + ENL++K+ +F+ L+++ + I
Sbjct: 63 EQQTLESTLLR-IHCSSELSE-IASANLVIEAIVENLEIKQGLFKELETICSADCILASN 120
Query: 417 XXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQ 596
LK + I H NP + LVE++ T +A+ ++ G++
Sbjct: 121 TSSISITAIASALKSPERFIGLHFFNPAPVMKLVEVIQGVATADNIAETAQQWARSCGKK 180
Query: 597 PVSLTREIDGFVLNRI 644
V L I GF++NR+
Sbjct: 181 SV-LACSIPGFIVNRV 195
>UniRef50_Q9XA30 Cluster: Putative 3-Hydroxyacyl-CoA dehydrogenase;
n=2; Streptomyces|Rep: Putative 3-Hydroxyacyl-CoA
dehydrogenase - Streptomyces coelicolor
Length = 504
Score = 77.0 bits (181), Expect = 4e-13
Identities = 51/193 (26%), Positives = 88/193 (45%)
Frame = +3
Query: 66 SEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGE 245
S + +VG+G +G+ A + G+ V +YD V + +A + I +L L L G
Sbjct: 7 SSPVAVVGTGTMGQGIAQVALVAGHPVRLYDAVDGRAREAADAIGARLDRLVEKDRLTGA 66
Query: 246 LKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 425
+ + + + + T + V E V E LD+K+++F+ L+ VV D+ +
Sbjct: 67 ERDAARARLVPAGT--LGELADCALVVEAVVERLDVKQELFRALEDVVGDDCLLATNTSS 124
Query: 426 XXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVS 605
L+ + + H NP +PLVE+V T P A + E G+ PV+
Sbjct: 125 LSVTAVGGALRVPGRFVGLHFFNPAPLLPLVEVVSGFATDPASATRAYETARAWGKTPVA 184
Query: 606 LTREIDGFVLNRI 644
+ GFV+NR+
Sbjct: 185 CA-DTPGFVVNRV 196
>UniRef50_Q67SZ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Symbiobacterium thermophilum|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Symbiobacterium thermophilum
Length = 517
Score = 77.0 bits (181), Expect = 4e-13
Identities = 52/202 (25%), Positives = 94/202 (46%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 251
++G+VG+G +G A + A G+ V +YDV + + A+ ++ L G + + +
Sbjct: 3 RLGVVGAGTMGAGIAQVAAQSGFDVLLYDVDPEALARALGRVESDLQRQAARGRI-PDAQ 61
Query: 252 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 431
+E I +T L A FV E PE+L+LK+++F+ LD + ++ +
Sbjct: 62 VAEVLGRITTTTSLGD-FAAADFVIEAAPEDLELKRRLFERLDRLCREDVVLATNTSSLS 120
Query: 432 XXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLT 611
+V+ H NP + LVE+V + + T + E +G+ PV +
Sbjct: 121 VTQIGALAGRADRVVGMHFFNPVPAMRLVEVVGGDASGEAALQATVSLAEAMGKVPVRV- 179
Query: 612 REIDGFVLNRIQYAILDEVWRL 677
R+ GF++NR+ E RL
Sbjct: 180 RDTPGFIVNRVARPFTGEALRL 201
>UniRef50_Q62DG4 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=48; Bacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase family protein - Burkholderia mallei
(Pseudomonas mallei)
Length = 331
Score = 77.0 bits (181), Expect = 4e-13
Identities = 52/209 (24%), Positives = 83/209 (39%)
Frame = +3
Query: 48 MASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLEND 227
MA K + +G+G+IG W + G V +D +++ LE
Sbjct: 11 MAVITKIDTFAAIGAGVIGSGWVARALANGLDVLAWDPAEDAEMQLRANVENAWPALERA 70
Query: 228 GLLRGELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIX 407
GL G A F + V A FVQE PE LK ++ + + + I
Sbjct: 71 GLAPGASPARLHFV-----PTIEACVADADFVQESAPEREALKLELHERISRAAKPDAII 125
Query: 408 XXXXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEI 587
+ IV HP NP Y +PLVE++ T P+ I +
Sbjct: 126 ASSTSGLLPTDFYARAHRPERCIVGHPFNPVYLLPLVEVLGGERTAPDTVDAALGIYRAL 185
Query: 588 GQQPVSLTREIDGFVLNRIQYAILDEVWR 674
G +P+ + +E+ GF+ +R +L+ +WR
Sbjct: 186 GMRPLRVRKEVPGFIADR----LLEALWR 210
>UniRef50_Q1AV58 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Rubrobacter xylanophilus DSM 9941|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 377
Score = 77.0 bits (181), Expect = 4e-13
Identities = 50/204 (24%), Positives = 93/204 (45%)
Frame = +3
Query: 66 SEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGE 245
+E++ +VG+G +G A A+ G++V + DV + + + ++ L G + E
Sbjct: 2 AERVAVVGAGTMGSGIAQSAAACGFEVALVDVSEEALERGMRSVRANLERRVERGRISSE 61
Query: 246 LKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 425
+ + I T L + GA V E V E++ +K++VF+ L+ VV + +
Sbjct: 62 ERDGVLGR-ISTFTSLESCA-GASLVIEAVVEDIGVKREVFRTLERVVGEEAVLATNTSS 119
Query: 426 XXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVS 605
+ +V+ H NP + LVE+V P + E + E +G+ PV
Sbjct: 120 LSVAEISATTRRPERVVGMHFFNPAPVMRLVEVVRGPRSGEEALARAEEAARRMGKTPVR 179
Query: 606 LTREIDGFVLNRIQYAILDEVWRL 677
++ + GF++NR+ E RL
Sbjct: 180 VS-DTPGFIVNRVARPFYLEALRL 202
>UniRef50_Q02A28 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Solibacter usitatus Ellin6076|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Solibacter usitatus (strain Ellin6076)
Length = 309
Score = 77.0 bits (181), Expect = 4e-13
Identities = 53/195 (27%), Positives = 89/195 (45%)
Frame = +3
Query: 81 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKASE 260
++G+G++G A+ A G Q T+ + + + +L + L+ EL A+
Sbjct: 8 VIGTGMMGPGIALTLALGGVQTTLLSRTPAGAERGVAEAR-RLGRV----LVEQELAAAL 62
Query: 261 QFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXX 440
I GSTD ++ A V E PE + K+++F +D V + +
Sbjct: 63 DLD-IAGSTDFEYSIGQADIVIESGPEEMGWKQELFARMDRVARADAVLASNTSGLSVTA 121
Query: 441 XXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREI 620
QV+ +H NPP+ VPLVEI+ T P A RE++ G+ PV + +
Sbjct: 122 IAAECARPEQVLATHFWNPPHLVPLVEIIQGRATSPAAAAAVRELLTACGKTPVVVKLDR 181
Query: 621 DGFVLNRIQYAILDE 665
G + NR+Q A++ E
Sbjct: 182 PGQLGNRLQMALVRE 196
>UniRef50_A0PRD1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase FadB3;
n=1; Mycobacterium ulcerans Agy99|Rep:
3-hydroxybutyryl-CoA dehydrogenase FadB3 - Mycobacterium
ulcerans (strain Agy99)
Length = 294
Score = 77.0 bits (181), Expect = 4e-13
Identities = 54/201 (26%), Positives = 92/201 (45%)
Frame = +3
Query: 63 KSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRG 242
+S + ++G+G +GR A++FAS G V +Y A+Q A + + L L D G
Sbjct: 13 RSRPVAVIGAGTLGRRIALMFASRGGTVRIYARRAEQRAQATQYVADNLPKLLQDRGF-G 71
Query: 243 ELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXX 422
E+ + C LATA++GA E VPE L++K ++ +D +TI
Sbjct: 72 EVGSVTATDC------LATALEGAWLAVESVPEKLEIKTALWGQIDQAAPPDTIFATNSS 125
Query: 423 XXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPV 602
+ ++ K+++ +H PP + L +++ T + ++ E G P
Sbjct: 126 SFPSRLMADNVRDKTRLCNTHFYMPPQFNAL-DLMSDGETDRGLLDTLLTVLPEFGVHPF 184
Query: 603 SLTREIDGFVLNRIQYAILDE 665
RE GF+ NR+ AI E
Sbjct: 185 EARRECTGFIFNRVWAAIKRE 205
>UniRef50_Q0C7S2 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative
uncharacterized protein - Aspergillus terreus (strain
NIH 2624)
Length = 589
Score = 77.0 bits (181), Expect = 4e-13
Identities = 56/205 (27%), Positives = 92/205 (44%), Gaps = 3/205 (1%)
Frame = +3
Query: 60 FKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIK-YQLHTLENDGLL 236
++ + I+G+G++GR A ++AS GY V V D +Q D + +K + + E+ G
Sbjct: 11 YRERPVAILGAGVLGRRIACIWASAGYDVQVRDPSPEQRADCVAYVKQHVVAYAEHTGAA 70
Query: 237 RGELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXX 416
GE+ SE DL V A V E VPE + LK F+ LD + + I
Sbjct: 71 PGEVTTSE---------DLKNTVNNAWLVIEAVPEKIQLKIDTFEQLDKLAPTDCILASN 121
Query: 417 XXXXXXXXXXEGLKH--KSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIG 590
+ + K +++ H PP V +VE++ +T P + + E +E
Sbjct: 122 SSSYKSSEMLDKVSDSAKPRILNMHYYMPP-QVMVVELMTNGFTDPSIIQFLVERSKEAA 180
Query: 591 QQPVSLTREIDGFVLNRIQYAILDE 665
P +E GF+ NR+ A+ E
Sbjct: 181 TIPYVARKESTGFIFNRLWAAVKRE 205
>UniRef50_Q12D24 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=5; Burkholderiales|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 511
Score = 76.6 bits (180), Expect = 6e-13
Identities = 56/206 (27%), Positives = 94/206 (45%)
Frame = +3
Query: 27 TVASTVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQ 206
T+ STV +K + +VG+G++G A + A G+ V +YD +A +
Sbjct: 2 TMNSTV---NKLDEAPLLVVGAGVMGVGIAQVAAQAGHAVMLYDAREGAAAEAKTKLAKS 58
Query: 207 LHTLENDGLLRGELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSV 386
L L G L + S+ I+ LA A + + E + E LD+K+ +FQ L+++
Sbjct: 59 LDALVAKGKLTAQ-GVSQTLSRIEAIASLAAAAPARLVI-EAIVEKLDVKRGLFQQLEAI 116
Query: 387 VDDNTIXXXXXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKT 566
V + + GL+H ++++ H NP + LVE+V T P VA
Sbjct: 117 VAADCVLATNTSSISVTAIANGLQHPARLVGMHFFNPVPQMRLVEVVSGLQTDPAVAALI 176
Query: 567 REIMEEIGQQPVSLTREIDGFVLNRI 644
++ G+ V R GF++NRI
Sbjct: 177 FDLAGVWGKVAVH-ARSTPGFIVNRI 201
>UniRef50_Q1QBD7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=2; Psychrobacter|Rep: 3-hydroxybutyryl-CoA
dehydrogenase precursor - Psychrobacter cryohalolentis
(strain K5)
Length = 533
Score = 76.2 bits (179), Expect = 8e-13
Identities = 48/190 (25%), Positives = 87/190 (45%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
+ + I+G+G++G A + A VG QV ++D A + ++ L L G E
Sbjct: 4 KSLAIIGTGIMGMGIAQIAAQVGIQVLLFDAKAGAAEQGRQSLQAMLEKLAAKGKFTDEQ 63
Query: 249 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 428
S I D+A + V + E + ENL++K+++F+ L+S+V TI
Sbjct: 64 LQSTLKNLIV-IEDIAKIAEADVVI-EAIIENLEIKQQLFKQLESIVPAETILATNTSSL 121
Query: 429 XXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
+H +V H NP + +VE++P TK V + + + +G V +
Sbjct: 122 AVTAIASNCEHPERVAGFHFFNPVPLMKIVEVIPGISTKSSVVETLTSLAKRMGHLGV-V 180
Query: 609 TREIDGFVLN 638
++ GF++N
Sbjct: 181 AKDTPGFIVN 190
>UniRef50_Q39NP5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=54;
cellular organisms|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 284
Score = 75.8 bits (178), Expect = 1e-12
Identities = 54/201 (26%), Positives = 88/201 (43%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
E +G+VG+G +G A A G V + DV + I +K L L + L
Sbjct: 4 EIVGVVGAGTMGNGIAQTAAVAGLNVVMIDVSDAALEKGIATLKGSLDRLVSKDKLDAAT 63
Query: 249 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 428
+ + + I STD A + A V E EN++LK ++ + +++V I
Sbjct: 64 RDAALAR-ITTSTDYAK-LAAADIVIEAATENVELKGRILKQIEAVARAEAIIATNTSSI 121
Query: 429 XXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
L ++ + H NP +PLVEI+ T A RE+ E + P+ +
Sbjct: 122 SITALAAPLADPARFVGMHFFNPVPLMPLVEIIRGLQTSDATASAVRELTERFDKSPIGV 181
Query: 609 TREIDGFVLNRIQYAILDEVW 671
R GFV+NRI +++E +
Sbjct: 182 -RNSPGFVVNRILVPMINEAF 201
>UniRef50_Q2W2Y1 Cluster: Glyoxysomal fatty acid beta-oxidation
multifunctional protein MFP-a; n=3;
Magnetospirillum|Rep: Glyoxysomal fatty acid
beta-oxidation multifunctional protein MFP-a -
Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)
Length = 703
Score = 75.8 bits (178), Expect = 1e-12
Identities = 55/191 (28%), Positives = 90/191 (47%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 251
K+GI+G+G +G AM FA++G VT+ DV + + + I+ + G L E +
Sbjct: 296 KVGIIGAGTMGGGIAMCFANIGIPVTIIDVSDENLQRGLGVIRKNYERSVSRGSLTQE-Q 354
Query: 252 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 431
+ + STD A A+K A E V E ++LKK +F LD+V+ I
Sbjct: 355 LESRMGLLSASTDYA-ALKDADLAIEAVFEKMELKKDIFAKLDAVLPAGAILGTNTSTLD 413
Query: 432 XXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLT 611
K + VI H +P +PL+EIV T +V ++ + I + V ++
Sbjct: 414 IDEIANTTKRPADVIGLHFFSPANVMPLLEIVQGKQTAMDVLLTALDMAKLIKKTGV-VS 472
Query: 612 REIDGFVLNRI 644
+ GF+ NR+
Sbjct: 473 KVCYGFIGNRM 483
>UniRef50_A5IDB6 Cluster: 3-hydroxyacyl CoA dehydrogenase; n=9;
Gammaproteobacteria|Rep: 3-hydroxyacyl CoA dehydrogenase
- Legionella pneumophila (strain Corby)
Length = 284
Score = 75.8 bits (178), Expect = 1e-12
Identities = 52/204 (25%), Positives = 94/204 (46%), Gaps = 3/204 (1%)
Frame = +3
Query: 63 KSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRG 242
K K+ ++G+G +G LFA G+ VT+ D + Q+ A + I LH L L
Sbjct: 2 KQTKLTLLGAGTMGSGITQLFAQYGFYVTLIDNLQSQLDKAKDTIAKNLHYL----ALTQ 57
Query: 243 ELKASEQFQCIKGSTDLAT---AVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXX 413
L+++ + I S T +K + ++ E + EN + KK ++Q L I
Sbjct: 58 NLESTHSIETILASITFTTKLDELKQSEYIIENITENWERKKALYQVLKKECSATCILGV 117
Query: 414 XXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQ 593
+ H +VI H +NP +P+VE++ T +KTR ++E++ +
Sbjct: 118 NTSSIPITKIASLVDHPQRVIGVHFMNPAPMMPMVEVIKGYHTDELTIEKTRTLLEQVHK 177
Query: 594 QPVSLTREIDGFVLNRIQYAILDE 665
+ + + ++ GFV NR ++E
Sbjct: 178 KMI-VVKDSVGFVSNRAMMIFINE 200
>UniRef50_Q9ADL9 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase;
n=7; Bacteria|Rep: Beta-hydroxybutyryl-CoA dehydrogenase
- Polyangium cellulosum (Sorangium cellulosum)
Length = 293
Score = 75.4 bits (177), Expect = 1e-12
Identities = 53/200 (26%), Positives = 89/200 (44%), Gaps = 3/200 (1%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
+G+VG+G++G A A G+ V + DV + A I+ L + G + +A
Sbjct: 12 VGVVGAGVMGVGVAQSLAQTGHDVVLVDVSEAALARARMGIRNGLRAVTLFGSAEDKKRA 71
Query: 255 SEQ---FQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 425
+ + + +TD + GA FV E V E D+K++V+ L+ V I
Sbjct: 72 GDPKAVLERVAFTTDYGR-LAGADFVVENVTEKWDIKREVYARLEGVCRPEIIFAADTSA 130
Query: 426 XXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVS 605
K SQV+ H +NP P+VE++ T PE + + E+G+ V
Sbjct: 131 ISITRIGSVTKRPSQVVGMHFMNPVPLKPMVEVIRGFHTSPETLGAAKRFLAEMGKTCV- 189
Query: 606 LTREIDGFVLNRIQYAILDE 665
+ + GFV NR+ ++E
Sbjct: 190 VVEDAPGFVSNRVLMLTINE 209
>UniRef50_A4FGV2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Actinomycetales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Saccharopolyspora erythraea (strain NRRL 23338)
Length = 517
Score = 74.5 bits (175), Expect = 2e-12
Identities = 47/201 (23%), Positives = 90/201 (44%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
+ ++G+G++GR A L A+ G V + D + ++ A++ + L G + E +A
Sbjct: 11 VRVIGTGVMGRGIAQLAAAAGLTVELADARQEAVSAAVDHVGEMFGKLVGKGRMSAE-EA 69
Query: 255 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 434
++ D V E V E+LD K+++F L+ V + +
Sbjct: 70 DAATARLRPVGDPLAPADSCDLVVEAVREDLDTKRELFAGLEEVCPRHAVLATNTSSLSV 129
Query: 435 XXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTR 614
L S++I H NP + LVE++P T+ +++ E++ +G QPV L
Sbjct: 130 TAIGAALADPSRLIGLHFFNPVPLMKLVEVIPGARTRQDLSADLVELVRRLGHQPV-LAT 188
Query: 615 EIDGFVLNRIQYAILDEVWRL 677
+ GF++N + E ++
Sbjct: 189 DTPGFLVNHAGRGLATEALQI 209
>UniRef50_Q9HRI4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7;
cellular organisms|Rep: 3-hydroxyacyl-CoA dehydrogenase
- Halobacterium salinarium (Halobacterium halobium)
Length = 286
Score = 74.5 bits (175), Expect = 2e-12
Identities = 53/207 (25%), Positives = 96/207 (46%), Gaps = 1/207 (0%)
Frame = +3
Query: 48 MASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQL-HTLEN 224
M S +E IG+VG+G +G A + A+ GY V + D+ + + + I+ L + N
Sbjct: 1 MRSLADTETIGVVGAGTMGAGIAQVAATAGYTVVMRDIEQEYVDAGFDSIESSLDRFVSN 60
Query: 225 DGLLRGELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 404
D L E A I G+TDLA V ++ V E++++K+ +F++LD + ++ +
Sbjct: 61 DDL--SEADADAIVDRITGTTDLAELADCDVVIEAAV-EDMEIKQDIFRDLDDALPEDVV 117
Query: 405 XXXXXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEE 584
S+V+ H +NP + VE+V T +V + E+
Sbjct: 118 LATNTSTLSITTIASVTDRASRVVGLHFMNPVPIMTGVEVVVGEKTDADVVAFAHALAED 177
Query: 585 IGQQPVSLTREIDGFVLNRIQYAILDE 665
+ ++ + + GFV NRI ++E
Sbjct: 178 LDKETWE-SDDKPGFVTNRILMPWINE 203
>UniRef50_Q84T13 Cluster: L-3-hydroxyacyl-CoA dehydrogenase subunit
precursor; n=1; Euglena gracilis|Rep:
L-3-hydroxyacyl-CoA dehydrogenase subunit precursor -
Euglena gracilis
Length = 320
Score = 73.7 bits (173), Expect = 4e-12
Identities = 53/197 (26%), Positives = 89/197 (45%), Gaps = 7/197 (3%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRG---- 242
+G+VG G +G A + A+ GY+V D+ A ++ I+ ++ L + + G
Sbjct: 25 VGVVGMGAMGHGIAQMTAAAGYKVVAVDIDANMLSKGIKAVEDSLSKVAAKAVKDGKADK 84
Query: 243 ---ELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXX 413
E A++ I S D+ A+ V E + E+L++KKK F +L V N I
Sbjct: 85 ATAEKNAADVRSRITTSGDIG-ALSSCDLVIESIIEDLNIKKKFFADLGKVAGANAILAS 143
Query: 414 XXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQ 593
E S + H NP + LVE++ TK +V K + IG+
Sbjct: 144 NTSSFPITQLGEASGRTSNFLGLHFFNPVQMMKLVEVIKTKDTKEDVYKLGFAFSKSIGK 203
Query: 594 QPVSLTREIDGFVLNRI 644
+PV+ + GF++NR+
Sbjct: 204 EPVA-CGDTPGFIVNRL 219
>UniRef50_O69856 Cluster: Fatty acid oxidation complex
alpha-subunit; n=6; Actinobacteria (class)|Rep: Fatty
acid oxidation complex alpha-subunit - Streptomyces
coelicolor
Length = 709
Score = 73.3 bits (172), Expect = 5e-12
Identities = 51/200 (25%), Positives = 91/200 (45%), Gaps = 1/200 (0%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFAS-VGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
K+G+VG+GL+ A+LF + V + D+ +++ + + ++ L G + +
Sbjct: 340 KVGVVGAGLMASQLALLFLRRLEVPVVLTDIDQERVDKGVGYVHAEIDKLLGKGRVNQD- 398
Query: 249 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 428
KA+ + G D A A FV E V E + +K+KVF +++V + I
Sbjct: 399 KANRLKALVTGVLDKAEGFADADFVIEAVFEEMGVKQKVFAEVEAVAPAHAILATNTSSL 458
Query: 429 XXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
LKH +V+ H NP +PL+EIV T + +++ + V L
Sbjct: 459 SVSEMASKLKHPERVVGFHFFNPVAILPLLEIVRGEQTDEAALATAFGVAKKLKKTAV-L 517
Query: 609 TREIDGFVLNRIQYAILDEV 668
++ FV+NRI + E+
Sbjct: 518 VKDAPAFVVNRILTRFMGEI 537
>UniRef50_A4SW27 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7;
Burkholderiales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Polynucleobacter sp. QLW-P1DMWA-1
Length = 313
Score = 73.3 bits (172), Expect = 5e-12
Identities = 36/119 (30%), Positives = 59/119 (49%)
Frame = +3
Query: 321 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXXEGLKHKSQVIVSHPVNPP 500
V ECVPE LD+K+++F L+ + GLK +++I H P
Sbjct: 83 VIECVPERLDIKQELFAKLEKYAKPEAVLASNSTSFPISEIASGLKTAARMIGLHFFMPA 142
Query: 501 YYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRL 677
+ VP VE+V T P V +M G PV++ +++ GF+ NR+Q+A+ E + +
Sbjct: 143 HLVPCVEVVYGEKTSPMVGDSLSRLMTACGMVPVTVKKDLPGFLANRLQHALSREAFAM 201
>UniRef50_A3U7V8 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerasefamily protein; n=19; Bacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerasefamily protein - Croceibacter
atlanticus HTCC2559
Length = 802
Score = 73.3 bits (172), Expect = 5e-12
Identities = 59/214 (27%), Positives = 99/214 (46%), Gaps = 17/214 (7%)
Frame = +3
Query: 54 SKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITD-------AIEDIKYQLH 212
+K + KI ++GSG++G A FA++G +V + D+V +++ + +ED K +
Sbjct: 2 AKRRINKIAVIGSGIMGSGIACHFANIGVEVLLLDIVPRELNEKEKAKGLTLED-KVVRN 60
Query: 213 TLENDGLLRG-ELKASEQFQ---CIKGST----DLATAVKGAVFVQECVPENLDLKKKVF 368
+ ND L + K + + + ST D VK ++ E V E LD+KK+VF
Sbjct: 61 RIVNDALQSSIKSKPAPLYHKDFASRISTGNLEDDIAKVKDVDWIIEVVVERLDIKKQVF 120
Query: 369 QNLDSVVDDNTIXXXXXXXXXXXXXXEGLKHKSQ--VIVSHPVNPPYYVPLVEIVPAPWT 542
+NL+ + T+ EG Q +H NPP Y+ L EI+P P T
Sbjct: 121 ENLEKHRTEGTLITSNTSGIPINLMSEGRSEDFQKHFCGTHFFNPPRYLELFEIIPGPKT 180
Query: 543 KPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 644
PEV E+ + + ++ F+ NR+
Sbjct: 181 SPEVLDFLNGYGEKFLGKTSIVAKDTPAFIGNRV 214
>UniRef50_Q68WH7 Cluster: Putative fatty acid oxidation complex
trifunctional enzyme [Includes: 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35); Enoyl-CoA
hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA
isomerase (EC 4.2.1.17) (EC 5.3.3.8)]; n=20;
Rickettsia|Rep: Putative fatty acid oxidation complex
trifunctional enzyme [Includes: 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35); Enoyl-CoA
hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA
isomerase (EC 4.2.1.17) (EC 5.3.3.8)] - Rickettsia typhi
Length = 720
Score = 73.3 bits (172), Expect = 5e-12
Identities = 49/202 (24%), Positives = 92/202 (45%), Gaps = 2/202 (0%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
+K+ ++G+G++G A L A+ ++V + D++ K D + +K + L L
Sbjct: 6 KKVCVIGAGVMGSGIAALIANSSHRVVLLDILDKDSNDPNKIVKNAVKNLHRQKLPPLSY 65
Query: 249 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 428
F I +K V E + E LD+K +++ + + ++TI
Sbjct: 66 PDKVNFITIGNLEHDLDLIKECNLVIEVIVEKLDIKHQLYNKIIPYLKEDTIIASNTSTL 125
Query: 429 XXXXXXEGLKH--KSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPV 602
E L + KS+ I++H NPP Y+ LVE++ K EV +K + +I + +
Sbjct: 126 PLKKLKENLPNNIKSRFIITHFFNPPRYMELVELIIDNTIKDEVIEKISVFLTKILGKTI 185
Query: 603 SLTREIDGFVLNRIQYAILDEV 668
+ GF+ NR+ +L+ V
Sbjct: 186 IKCNDTPGFIANRVGCFLLELV 207
>UniRef50_A0JVH8 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=12; Actinomycetales|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Arthrobacter sp. (strain FB24)
Length = 723
Score = 72.9 bits (171), Expect = 7e-12
Identities = 53/200 (26%), Positives = 93/200 (46%), Gaps = 1/200 (0%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFA-SVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
K+G+VG+GL+ A+LFA + V + D+ ++ + + ++ + + +
Sbjct: 350 KVGVVGAGLMASQLALLFARQLKVPVVMTDIDQARVDKGVGYVHAEVDKMLAKKRISADA 409
Query: 249 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 428
A+ + GS A A FV E V E L++KK+VF ++++V I
Sbjct: 410 -ANRTKALVTGSVS-KDAFADADFVIEAVFEELNVKKQVFAEVEAIVSPECILATNTSSL 467
Query: 429 XXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
L H +++ H NP +PL+EIV AP T V E+ + + + V L
Sbjct: 468 SVTAMAADLAHPERLVGFHFFNPVAVMPLLEIVRAPKTDDAVLATAFELAKGLKKTAV-L 526
Query: 609 TREIDGFVLNRIQYAILDEV 668
++ FV+NRI ++ EV
Sbjct: 527 VKDAAAFVVNRILLRLMGEV 546
>UniRef50_A1CC71 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putative;
n=2; Aspergillus|Rep: 3-hydroxyacyl-CoA dehydrogenase,
putative - Aspergillus clavatus
Length = 307
Score = 72.5 bits (170), Expect = 1e-11
Identities = 57/199 (28%), Positives = 89/199 (44%), Gaps = 2/199 (1%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDG--LLRGEL 248
+ ++G G++GR M++A+ G+ V +Y+ K A+ +KY L LL G+
Sbjct: 16 VAVIGGGVLGRRLCMMWAAAGHTVQLYE---KSPEVAVAALKYIHEALPQQASKLLLGK- 71
Query: 249 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 428
KA + ++ L TAV+ A V E +PE L LK ++F LD + + I
Sbjct: 72 KAGHGIGHVSPASSLETAVQNAWMVIEAIPELLPLKIELFGQLDQLAPADCILATNSSSY 131
Query: 429 XXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
E + +++V +H PP L EI+ +T P + E G PV
Sbjct: 132 KSREMLEKVARRARVCNAHYYMPPEQNHL-EIMTCGFTDPAIISFLLEQAAAAGFVPVHA 190
Query: 609 TREIDGFVLNRIQYAILDE 665
E G + NRI AI E
Sbjct: 191 KVESTGLIFNRIWAAIKRE 209
>UniRef50_Q47M90 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5;
root|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Thermobifida fusca (strain YX)
Length = 398
Score = 72.1 bits (169), Expect = 1e-11
Identities = 56/195 (28%), Positives = 88/195 (45%), Gaps = 4/195 (2%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDA-IEDIKYQLHTLENDGLLRGEL 248
K+G+VG G +G +FA G+ VT +I DA +E + L + +G+L
Sbjct: 7 KVGVVGLGTMGAGIVEVFARAGFTVT-----GVEIDDAALERGRTHLEKSLAKAVAKGKL 61
Query: 249 KASEQFQCIKGSTDLATA---VKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXX 419
EQ + I G T+ + A E VPE LD+K+ VF +LD ++ I
Sbjct: 62 TEDEQ-RAILGRVTFTTSRDDLADAHLAVEAVPERLDIKRSVFADLDRILPPAAILATNT 120
Query: 420 XXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQP 599
+VI H NP + LVEIV T+P V + +++ +G+ P
Sbjct: 121 SSLSVTEIAALTSRPGKVIGLHFFNPAPVMRLVEIVTTVVTEPHVRETATQVVTRLGKTP 180
Query: 600 VSLTREIDGFVLNRI 644
V++ + GFV N +
Sbjct: 181 VAV-GDRAGFVANAL 194
>UniRef50_A0QZR0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Mycobacterium smegmatis str. MC2 155|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Mycobacterium
smegmatis (strain ATCC 700084 / mc(2)155)
Length = 296
Score = 72.1 bits (169), Expect = 1e-11
Identities = 50/192 (26%), Positives = 88/192 (45%), Gaps = 3/192 (1%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
+ ++G+G +G A + A G++ +YD+ + I+ + H + + G+L A
Sbjct: 12 VAVLGAGTMGSGIATVMARAGHRTILYDINEANLERGIDTV----HGFFDKSVRLGKLDA 67
Query: 255 SE---QFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 425
+ + GST+L V V E V E+L LKK+ F LD +V T+
Sbjct: 68 TAGQAAKDSLSGSTELKDLAPCDVVV-EAVFEDLSLKKETFGRLDDIVPPTTLFHTNTST 126
Query: 426 XXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVS 605
G + + +V+ +H NP + LVE+ T K T E + +G+ V
Sbjct: 127 LSVTGIASGSRLRERVVGTHYCNPAPLMKLVEVANGRHTADWAHKATLEFLASLGKTSV- 185
Query: 606 LTREIDGFVLNR 641
+T++ GF++NR
Sbjct: 186 VTKDRPGFIVNR 197
>UniRef50_Q5P039 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
Proteobacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum
(strain EbN1))
Length = 443
Score = 71.7 bits (168), Expect = 2e-11
Identities = 51/191 (26%), Positives = 88/191 (46%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 251
++G++G+G +G AM FA+VG VTV D + +E ++ G L
Sbjct: 43 RVGVIGAGTMGGGIAMSFANVGIPVTVCDTDGAALERGLERVRRNYEFSVARGRLDAATM 102
Query: 252 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 431
A+ + I+ + DL +K A V E V E++ LK+ +F+ LD++V + I
Sbjct: 103 AA-RLALIRAAVDLQD-LKDADLVIEAVFEDMALKQDIFRKLDAIVHPDAILATNTSGLD 160
Query: 432 XXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLT 611
+ V+ +H +P + L+E+V T PEV + +G+ V L+
Sbjct: 161 IDEIAVVTRRPQDVVGAHFFSPAHVQKLLEVVRGARTAPEVIATLMSLGRRMGKVSV-LS 219
Query: 612 REIDGFVLNRI 644
R GF+ N +
Sbjct: 220 RIYPGFIGNAL 230
>UniRef50_Q1ATL4 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Rubrobacter xylanophilus DSM 9941|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Rubrobacter
xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 287
Score = 71.7 bits (168), Expect = 2e-11
Identities = 46/201 (22%), Positives = 87/201 (43%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
+G++G+G +G + A GY+V D + + A ++ L + G L E +A
Sbjct: 5 VGVLGTGTMGAGIVQVAARAGYRVVACDASEEALGKARRYVRSGLESFARRGALSEE-EA 63
Query: 255 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 434
++ +T + + G+ V E + E + KK+ F LD+++ + +
Sbjct: 64 EAALGRVRWTTAMEE-LAGSEAVIEAIVERVGPKKEAFAALDALLPPDALLLTNTSSISI 122
Query: 435 XXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTR 614
+V +H PP VE+V T E ++ R ++ G+ PV + +
Sbjct: 123 TELASATGRPERVCGAHFFTPPPLREAVEVVRGEQTSDETVERVRRLLSSFGKLPVVVRK 182
Query: 615 EIDGFVLNRIQYAILDEVWRL 677
++ GF NR+ +L E RL
Sbjct: 183 DVPGFAANRLLMPVLLEAARL 203
>UniRef50_A5V327 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Sphingomonas wittichii RW1
Length = 748
Score = 71.7 bits (168), Expect = 2e-11
Identities = 50/188 (26%), Positives = 84/188 (44%)
Frame = +3
Query: 81 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKASE 260
I+G+G +G AM FA G V + D + + +E ++ T G + E + +
Sbjct: 349 IIGAGTMGGGIAMCFAGAGIPVVIVDTTQEALDRGMERVRANYATSVKRGSISQE-QVDK 407
Query: 261 QFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXX 440
+ I +TD A AV A V E V E++ +KK++F +L+ V T+
Sbjct: 408 RLALITPATDRA-AVADADLVIEAVFEDMAVKKEIFSDLEKRVKPGTVLASNTSALDVDE 466
Query: 441 XXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREI 620
L + H +P + L+E+V A + PE + +IG+ PV +
Sbjct: 467 IAAALDRPEDFVGMHFFSPANVMKLLEVVQAAKSSPEAILTAMAVGRKIGKVPV-WSGNC 525
Query: 621 DGFVLNRI 644
DGF+ NR+
Sbjct: 526 DGFIGNRM 533
>UniRef50_A1SEZ9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Nocardioides sp. JS614|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Nocardioides sp. (strain BAA-499 /
JS614)
Length = 275
Score = 71.7 bits (168), Expect = 2e-11
Identities = 55/204 (26%), Positives = 93/204 (45%)
Frame = +3
Query: 66 SEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGE 245
S + +VG G +GR A+ + G++VT+ DV A+ + D + + H + RG
Sbjct: 2 STSMVVVGGGTMGRGIAIAALATGFEVTLVDV-AEDVLDRAQ-ARVSEHFARHPQPDRGV 59
Query: 246 LKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 425
L + T LA +++ A V E VPE L LK ++FQ L T+
Sbjct: 60 LHTT---------TSLAGSLETAEVVIEAVPEILPLKTQIFQQLRGA-PPGTLLVSNTST 109
Query: 426 XXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVS 605
E S+V+ H NP + +PLVE+V T + + + +G+ P+
Sbjct: 110 MSISALAEACGGSSRVVGMHFFNPAHRMPLVEVVVGTRTSDDARDRAVALAVRLGKDPI- 168
Query: 606 LTREIDGFVLNRIQYAILDEVWRL 677
+ R++ GFV +R+ + E R+
Sbjct: 169 VVRDLPGFVTSRLGLILGTEAMRM 192
>UniRef50_A5VHQ1 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=2; Lactobacillus reuteri|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Lactobacillus reuteri F275
Length = 294
Score = 71.3 bits (167), Expect = 2e-11
Identities = 55/198 (27%), Positives = 90/198 (45%), Gaps = 1/198 (0%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
+ I I G+G++G A A G+ V+VY+ I A IK E D L +
Sbjct: 2 KNIMIAGAGVLGSQIAYQTALSGFNVSVYN---HHIDTAERRIKALKSDYERD-LHLTDK 57
Query: 249 KASEQFQCIKGSTD-LATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 425
+ + IK TD +ATAVK A + E +PE+L+LK++ ++ + + + TI
Sbjct: 58 EFQQGLNNIKVITDDVATAVKDADLMIEALPESLELKEQFYEEVSELAPEKTIFASNSST 117
Query: 426 XXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVS 605
+ + H N + +VEI+ T PEV ++ + EI PV
Sbjct: 118 FIPSQLAPYTDRPEKFLNMHFANQIWKFNVVEIMGTSQTSPEVIEEATKFAREIKMVPVI 177
Query: 606 LTREIDGFVLNRIQYAIL 659
L +E G++LN + +L
Sbjct: 178 LNKEQHGYILNSLLIPLL 195
>UniRef50_Q1IIH2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5;
cellular organisms|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Acidobacteria bacterium (strain
Ellin345)
Length = 282
Score = 70.9 bits (166), Expect = 3e-11
Identities = 51/201 (25%), Positives = 92/201 (45%), Gaps = 3/201 (1%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLL---RG 242
K+G++G+G +G A +FA GY+V + DV + + + IK L + +G
Sbjct: 5 KVGVIGAGTMGNGIAHVFAKSGYKVVLCDVKREFLDRGLATIKKNLEREVAKNKISQEQG 64
Query: 243 ELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXX 422
++ A + ++ DLA V E E ++K ++F++LDS+ + I
Sbjct: 65 QVAADHIYPTLERK-DLADCD----IVVEAASERFEIKAELFRDLDSICRPDVILATNTS 119
Query: 423 XXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPV 602
K +VI H NP + LVE++ T E + + + E++ + PV
Sbjct: 120 SISITKIAAVTKRPDKVIGMHFFNPVPVMKLVEVIRGLATSDETYQAVKVLSEKLEKTPV 179
Query: 603 SLTREIDGFVLNRIQYAILDE 665
+ + GFV NR+ +L+E
Sbjct: 180 EV-NDAPGFVSNRVLMPLLNE 199
>UniRef50_Q4PFL4 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 344
Score = 70.9 bits (166), Expect = 3e-11
Identities = 60/224 (26%), Positives = 98/224 (43%), Gaps = 10/224 (4%)
Frame = +3
Query: 36 STVIMASKFKSEKIGIVGSGLIGRSWAMLFASVG-YQVTVYDVVAKQITDAIEDIKYQLH 212
ST ++ +K + I + G+GL+G A + A G + VT+ DV K + + I L
Sbjct: 32 STSLVQNK-DVQNITVFGAGLMGAGIAQVLAHKGKFNVTLSDVTDKALANGQTIISKSLG 90
Query: 213 TLENDGLLRGELKASEQFQCIKG-------STDLATAVKGAVFVQECVPENLDLKKKVFQ 371
+ + E A EQ Q +KG +TD AVK V E + EN+ +KK +F
Sbjct: 91 RIVKKSM--AEASAEEQAQYVKGIVDSIKVTTDPEAAVKDTDLVIEAIIENVGIKKDLFG 148
Query: 372 NLDSVVDDNTIXXXXXXXXXXXXXXEGLKHKSQVIVS--HPVNPPYYVPLVEIVPAPWTK 545
LD + + E + + Q + H NP + LVE+V T
Sbjct: 149 FLDGKAPKDALFASNTSSLSITDVAEAVSAQRQELFGGFHAFNPVPQMKLVEVVRTTKTS 208
Query: 546 PEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRL 677
+ E+ + +G+ PV+ + GF++NR+ + E RL
Sbjct: 209 NDTFDSLTEVAKRMGKTPVACI-DSPGFIVNRLLVPYMLEAIRL 251
>UniRef50_A3YFA8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Marinomonas sp. MED121|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Marinomonas sp. MED121
Length = 545
Score = 70.5 bits (165), Expect = 4e-11
Identities = 50/203 (24%), Positives = 90/203 (44%), Gaps = 2/203 (0%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
IG+VG+G +G A + + G++V +YD Q +A K + L N + +G +
Sbjct: 17 IGVVGAGAMGAGIAQVASQAGHKVFLYD----QNEEASFRAKESISLLLNKKVAKGTITR 72
Query: 255 SEQFQCIKGSTDLATA--VKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 428
CI L + +K A + E + E L++K+ +F+ L+ + I
Sbjct: 73 EHYDTCIANIIPLHSLDELKSADLIIEAIVETLEIKQSLFRALELICKPECILASNTSSI 132
Query: 429 XXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
LK+ + + H NP +PLVE++ + +AK+ + G+ PV
Sbjct: 133 SITAIASCLKYPERFLGLHFFNPAPVMPLVEVISGLASDQLIAKQLYDTCLLWGKTPVK- 191
Query: 609 TREIDGFVLNRIQYAILDEVWRL 677
T+ GF++NR+ E R+
Sbjct: 192 TKSTPGFIVNRVARPFYAEALRI 214
>UniRef50_O44608 Cluster: Hydroxy-acyl-coa dehydrogenase protein 1;
n=2; Caenorhabditis|Rep: Hydroxy-acyl-coa dehydrogenase
protein 1 - Caenorhabditis elegans
Length = 299
Score = 70.1 bits (164), Expect = 5e-11
Identities = 50/197 (25%), Positives = 85/197 (43%), Gaps = 7/197 (3%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK- 251
+ I G+G++G A + GY V +Y K++ +A E IK L + + ++
Sbjct: 13 VAIFGAGMMGSGIAQVCLQAGYPVNLYGRSEKKLLEARETIKKNLIRVASKKKTDVPMEP 72
Query: 252 ------ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXX 413
A Q ++ TD+ +A + A E V ENLDLK +FQ + N +
Sbjct: 73 AALEEIAQIQLDLLQIHTDIPSAAEDAAMAIEAVAENLDLKLDIFQTIQKTCPQNCMLIT 132
Query: 414 XXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQ 593
+++ + H NP + LVE+V T PE +EI +
Sbjct: 133 NTSSLKLSQMLPVIQNPALFAGLHFFNPVPVMKLVEVVSTDETSPETTNFLFNFCKEIKK 192
Query: 594 QPVSLTREIDGFVLNRI 644
PV+ ++ GF++NR+
Sbjct: 193 LPVA-AKDTPGFIVNRL 208
>UniRef50_Q3KCL0 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Pseudomonas fluorescens PfO-1|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Pseudomonas fluorescens (strain PfO-1)
Length = 703
Score = 69.7 bits (163), Expect = 7e-11
Identities = 52/205 (25%), Positives = 89/205 (43%)
Frame = +3
Query: 63 KSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRG 242
K K+ ++G+G +G AM FA VG V + D+ + + ++ ++ G L
Sbjct: 297 KINKVAVIGAGTLGGGIAMSFADVGIPVALMDLDGRTLDRGLKRVRENYQLSVKRGKLSA 356
Query: 243 ELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXX 422
++ ++ + + G+ D A + A + E V E ++ K +VF L+SV I
Sbjct: 357 -VQMQQRMELLFGTLDYAD-LSDADLIIEAVCEKMESKHQVFLALESVCKPGAILATNTS 414
Query: 423 XXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPV 602
+ + VI H +P + LVEIV T P+V +I IG+ PV
Sbjct: 415 SLDIDALAKMVSRPQDVIGMHFFSPANVMRLVEIVLCQTTAPDVVTAVMDIARRIGKLPV 474
Query: 603 SLTREIDGFVLNRIQYAILDEVWRL 677
++ G + NR+ E RL
Sbjct: 475 -ISGNSAGSIGNRMLEPYAREAHRL 498
>UniRef50_O29090 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 312
Score = 69.7 bits (163), Expect = 7e-11
Identities = 53/191 (27%), Positives = 94/191 (49%), Gaps = 1/191 (0%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQ-LHTLENDGLLRGELK 251
I ++G+G +G + A+LFA+ G++VT+ D + A + + + L LE GL + +
Sbjct: 5 IAVIGAGTMGAAIALLFANAGFEVTLVDKSRGALRRAEDRHRGESLEELEEAGLRKQDNP 64
Query: 252 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 431
AS I +T+L V F+ E + E L K ++F+ ++ ++ +
Sbjct: 65 AS----LITYTTEL--RVYECDFIVEAIVERLRDKIELFRKIEE-INSPAVLATNTSSFM 117
Query: 432 XXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLT 611
L + ++ + H NPP +PLVE V E ++ E+ + IG++PV L
Sbjct: 118 PSEIARHLANPERLTLFHFSNPPILMPLVE-VGGEIVSDETVERAVEMAKSIGKEPVVLR 176
Query: 612 REIDGFVLNRI 644
+E G VLNR+
Sbjct: 177 KECRGHVLNRM 187
>UniRef50_Q0SEM1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 286
Score = 69.3 bits (162), Expect = 9e-11
Identities = 49/190 (25%), Positives = 85/190 (44%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
+G+VG+G +G A A G+ V V D + + A ++ L G G K
Sbjct: 9 VGVVGAGTMGAGVAECLAQAGHDVIVVDPDPQAVDQARSRMRDSLRLAILLGRAGGP-KP 67
Query: 255 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 434
+E + + ++ T ++ A V ECVPE +DLK+KVF LD V + +
Sbjct: 68 AEVTARVHWTGEM-TDLRDAAVVIECVPERIDLKEKVFAELDRVCAPDALLASCTSGIPV 126
Query: 435 XXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTR 614
+ +V+ H +NP VE+V P T P+ + ++ + + + +
Sbjct: 127 DRLADTTTRPERVVGLHFMNPAPLKDTVEVVRGPRTSPQSLDRALALLASLNKTGI-VVG 185
Query: 615 EIDGFVLNRI 644
+ GF+LNR+
Sbjct: 186 DGPGFLLNRV 195
>UniRef50_A0IJE2 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=5; Gammaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Serratia proteamaculans 568
Length = 506
Score = 69.3 bits (162), Expect = 9e-11
Identities = 46/201 (22%), Positives = 87/201 (43%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 251
++ ++G+G +G A + A+ G+QV ++D+ A A+ + +L G + +
Sbjct: 9 RVAVIGAGTMGIGIAQVAAAAGHQVQLFDIAASAARQALGALAQRLRQRVAAG--KADAT 66
Query: 252 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 431
+E + ++ + V E V E L +K+ +F+ L+++ T+
Sbjct: 67 TTEALLARIQPAESLNSLADSGLVIEAVAEKLAIKQSLFRELEALCSPATLFASNTSSLS 126
Query: 432 XXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLT 611
L+H ++ H NP + LVEIV T E + + + G+Q V L
Sbjct: 127 ITAIAGALQHPQRLAGLHFFNPAPLMKLVEIVSGLDTSTETVATLQRLTRQWGKQSV-LC 185
Query: 612 REIDGFVLNRIQYAILDEVWR 674
R GF++NR+ E R
Sbjct: 186 RSTPGFIVNRVARPFYAEALR 206
>UniRef50_A5V4A1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Sphingomonas wittichii RW1|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Sphingomonas wittichii RW1
Length = 489
Score = 68.5 bits (160), Expect = 2e-10
Identities = 49/190 (25%), Positives = 84/190 (44%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
I +VG+G +G A++ A G+ V V D + + + L +L G + E A
Sbjct: 9 IAVVGAGTMGAGIALVAAQAGHAVRVIDTQDAALDRGRQSVARSLASLVKRGTI-DEAGA 67
Query: 255 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 434
+ + I STD+A A A+ + E + E +D+K +F+ L V I
Sbjct: 68 AAIAERIGWSTDVADAAPAALAI-EAIVERMDVKTGLFETLARHVAPGAILASNTSSLSI 126
Query: 435 XXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTR 614
+ + H NP + LVE++P+ T P V +M + PV + R
Sbjct: 127 EAMASAVPGPERFAGLHFFNPVPAMKLVELIPSSRTAPTVVDDLEALMRAWKKLPVRV-R 185
Query: 615 EIDGFVLNRI 644
++ GF++NR+
Sbjct: 186 DVPGFIVNRV 195
>UniRef50_A1I839 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Candidatus
Desulfococcus oleovorans Hxd3
Length = 289
Score = 68.5 bits (160), Expect = 2e-10
Identities = 52/193 (26%), Positives = 86/193 (44%), Gaps = 1/193 (0%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
+++ I G+G +GRS + A G +V +YDV + A + ++ + G L E
Sbjct: 7 KRVLIAGAGTMGRSIGLSCAVRGCEVILYDVKEDALEAARRAMAVKIDKMVPAGALTPE- 65
Query: 249 KASEQFQC-IKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 425
A+E + I +TDLA A A V E VPE+ D+K + F+ L V + TI
Sbjct: 66 -AAESIKANITTTTDLAAAGADADLVSESVPEDPDIKGEFFEKLHGVCPERTIFTTNTSS 124
Query: 426 XXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVS 605
+ + H +P + LV+++ T E + R E IG P+
Sbjct: 125 LVPSMFAARTGRPDRFLAFH-FHPGF--KLVDVMGHAGTSAETVETVRRFAERIGHSPIV 181
Query: 606 LTREIDGFVLNRI 644
L +E G++ N +
Sbjct: 182 LKQEKAGYLFNSL 194
>UniRef50_P45364 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=13;
Clostridia|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Clostridium difficile
Length = 281
Score = 68.5 bits (160), Expect = 2e-10
Identities = 51/198 (25%), Positives = 85/198 (42%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 251
K+ ++GSG +G FAS G+ V + I + + L L G K
Sbjct: 2 KLAVIGSGTMGSGIVQTFASCGHDVCLKSRTQGAIDKCLALLDKNLTKLVTKGKWMKATK 61
Query: 252 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 431
A E + +T+ +K + E E++++KK VF+ LD + ++TI
Sbjct: 62 A-EILSHVSSTTNYED-LKDMDLIIEASVEDMNIKKDVFKLLDELCKEDTILATNTSSLS 119
Query: 432 XXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLT 611
K +VI H NP + LVE++ T E+ + I + PV ++
Sbjct: 120 ITEIASSTKRPDKVIGMHFFNPVPMMKLVEVISGQLTSKVTFDTVFELSKSINKVPVDVS 179
Query: 612 REIDGFVLNRIQYAILDE 665
E GFV+NRI +++E
Sbjct: 180 -ESPGFVVNRILIPMINE 196
>UniRef50_Q5KVJ3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=16;
Bacillaceae|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Geobacillus kaustophilus
Length = 795
Score = 68.1 bits (159), Expect = 2e-10
Identities = 55/213 (25%), Positives = 93/213 (43%), Gaps = 17/213 (7%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIE------DIKYQLHTLENDGL 233
+ ++GSG++G A A+VG + D+V +++T E + K + L N L
Sbjct: 7 RAAVLGSGVMGSGIAAHLANVGIPTLLLDIVPRELTKEEEAKGWTLEHKQVRNRLANQAL 66
Query: 234 LR------GELKASEQFQCIKGST--DLATAVKGAVFVQECVPENLDLKKKVFQNLDSVV 389
R L + + I+ D + ++ E V E L++KK+VF +D V
Sbjct: 67 ERLLKQKPAPLMSKDNIALIETGNFEDDFHRLAEVDWIIEAVVEKLEVKKEVFARVDEVR 126
Query: 390 DDNTIXXXXXXXXXXXXXXEGLKH--KSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKK 563
TI EG K + +H NPP Y+ L+EI+P T P+V
Sbjct: 127 TPGTIVSSNTSGISIAAMAEGRSDDFKKHFLGTHFFNPPRYLKLLEIIPTEHTDPDVVAY 186
Query: 564 TREIMEEIGQQPVSLTREIDGFVLNRI-QYAIL 659
+ E++ + V + ++ F+ NRI Y +L
Sbjct: 187 MKSFGEDVLGKGVVMAKDTPNFIANRIGTYGLL 219
>UniRef50_Q3A7N5 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Pelobacter carbinolicus DSM 2380|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Pelobacter carbinolicus (strain DSM 2380
/ Gra Bd 1)
Length = 304
Score = 68.1 bits (159), Expect = 2e-10
Identities = 51/186 (27%), Positives = 78/186 (41%)
Frame = +3
Query: 81 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKASE 260
+VG G +GR A A+ GY VT+YD+ A+ + + I L +G ++ + A
Sbjct: 11 VVGGGTMGRQIAFQCAAHGYFVTIYDISAEVLQATQKRIGAYADYLVAEGHIQPQ-AAKR 69
Query: 261 QFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXX 440
I STD A A + E VPE+ LK +VF D TI
Sbjct: 70 AINRISISTD-ARQAANADLLCEAVPEDPALKGEVFARFDRYCPQRTIFSTNASLLVPSQ 128
Query: 441 XXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREI 620
+ + + H P + L +++P T EV K + + I Q P+ L +E
Sbjct: 129 IAKATGRPDRFLALHFHQPVWVGNLADVMPHAGTSSEVVKVVHDFAKSINQIPLVLNKEN 188
Query: 621 DGFVLN 638
G+V N
Sbjct: 189 FGYVFN 194
>UniRef50_A7PEM6 Cluster: Chromosome chr11 scaffold_13, whole genome
shotgun sequence; n=3; core eudicotyledons|Rep:
Chromosome chr11 scaffold_13, whole genome shotgun
sequence - Vitis vinifera (Grape)
Length = 724
Score = 67.7 bits (158), Expect = 3e-10
Identities = 46/191 (24%), Positives = 86/191 (45%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
+K+ ++G GL+G A + V + +V ++ + I+ I+ + L G L +
Sbjct: 309 KKVAVIGGGLMGSGIATALITSNIYVVLKEVNSEYLLKGIKTIEANVRGLVTKGKLTQD- 367
Query: 249 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 428
KA + +KG D + K V E V EN+ LK+K+F ++ + + I
Sbjct: 368 KARKALSMLKGVLDYSE-FKDIDMVIEAVIENISLKQKIFSEIEKICSPHCILATNTSTI 426
Query: 429 XXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
E + ++I +H +P + +PL+E+V T +V + + I + PV +
Sbjct: 427 DLNLVGEKTSSQDRIIGAHFFSPAHVMPLLEVVRTEKTSAQVILDLMTVGKAIKKIPV-V 485
Query: 609 TREIDGFVLNR 641
GF +NR
Sbjct: 486 VGSCTGFAVNR 496
>UniRef50_P45856 Cluster: Probable 3-hydroxybutyryl-CoA
dehydrogenase; n=65; Bacteria|Rep: Probable
3-hydroxybutyryl-CoA dehydrogenase - Bacillus subtilis
Length = 287
Score = 67.7 bits (158), Expect = 3e-10
Identities = 52/199 (26%), Positives = 87/199 (43%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
++I + G+G +G A A G+ V +YDV + ++ +K QL G R E
Sbjct: 4 KQIMVAGAGQMGSGIAQTAADAGFYVRMYDVNPEAAEAGLKRLKKQLARDAEKGK-RTET 62
Query: 249 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 428
+ I S L A + A V E + EN+ K ++F+ LD + +TI
Sbjct: 63 EVKSVINRISISQTLEEA-EHADIVIEAIAENMAAKTEMFKTLDRICPPHTILASNTSSL 121
Query: 429 XXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
+VI H +NP + LVE++ T E A + E++G+ V +
Sbjct: 122 PITEIAAVTNRPQRVIGMHFMNPVPVMKLVEVIRGLATSEETALDVMALAEKMGKTAVEV 181
Query: 609 TREIDGFVLNRIQYAILDE 665
+ GFV NR+ +++E
Sbjct: 182 -NDFPGFVSNRVLLPMINE 199
>UniRef50_Q7VRZ0 Cluster: Probable enoyl-CoA
hydratase/3-hydroxyacyl-CoA dehydrogenase, bifunctional
enzyme; n=3; Bordetella|Rep: Probable enoyl-CoA
hydratase/3-hydroxyacyl-CoA dehydrogenase, bifunctional
enzyme - Bordetella pertussis
Length = 705
Score = 66.9 bits (156), Expect = 5e-10
Identities = 48/188 (25%), Positives = 83/188 (44%)
Frame = +3
Query: 81 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKASE 260
+VG+G +GR A+ A G +V DV + A+E I+ +L G + E A +
Sbjct: 308 VVGAGTMGRGIAIALADAGLRVRFIDVEQASLDRALEAIRAHYRSLAARGRMT-EAAARD 366
Query: 261 QFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXX 440
I ++D+ A + V V E E+L +K+ +F+ LDS+V +
Sbjct: 367 AVARISPASDMQAAAEADVVV-EAAFEDLAIKQAIFRQLDSIVRPGAVLATNTSTLDVDA 425
Query: 441 XXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREI 620
+ V+ +H +P + L+E+V T P + +G+ V++
Sbjct: 426 IAAATRRPQDVVGTHFFSPANVMRLLEVVRGARTAPRTLGAVLALGRRMGKVCVTV-GVC 484
Query: 621 DGFVLNRI 644
DGFV NR+
Sbjct: 485 DGFVANRM 492
>UniRef50_Q8FUX6 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=4; Brucella|Rep: 3-hydroxyacyl-CoA
dehydrogenase family protein - Brucella suis
Length = 501
Score = 66.5 bits (155), Expect = 6e-10
Identities = 46/189 (24%), Positives = 87/189 (46%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 251
K+ I+GSG++G A A+ G V ++D +A + + A + ++L + G L G +
Sbjct: 8 KVAIIGSGVMGAGIAETMAAGGIDVLLFDQMADKASAAKLALSHRLQSRVERGKL-GADR 66
Query: 252 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 431
A++ + I L V A V E + ENL +KK + L++++ +
Sbjct: 67 AAQILERIVPVQQLDEIVS-ADLVVEAIVENLTVKKDLVAALEAILPRQAVIATNTSSLS 125
Query: 432 XXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLT 611
K+ ++ H NP + +VE++ T V +E+ +G +PV+ T
Sbjct: 126 VTAIAASAKYPERIAGFHFFNPVPLMRVVEVIKGALTGDAVVDALKELAVRVGHRPVNAT 185
Query: 612 REIDGFVLN 638
+ GF++N
Sbjct: 186 -DTPGFIIN 193
>UniRef50_Q39TJ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like; n=1;
Geobacter metallireducens GS-15|Rep: 3-hydroxyacyl-CoA
dehydrogenase-like - Geobacter metallireducens (strain
GS-15 / ATCC 53774 / DSM 7210)
Length = 290
Score = 66.5 bits (155), Expect = 6e-10
Identities = 52/206 (25%), Positives = 87/206 (42%), Gaps = 3/206 (1%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
+K+ I+G+G++G A+ A GY V + +V +E I+ L G L +
Sbjct: 5 KKVAILGAGMMGSDIALSCALAGYDVLLKEVSLDLAAAGVERIRGSLAKWSEKGRLAVDA 64
Query: 249 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX- 425
+ + D + V E + E+LD+K + F+ L+ V + I
Sbjct: 65 EQQKSAVARITPVDNFSGFGDVDLVIEAIFEDLDVKSQNFRQLEEVCKPSCIIASNTSSL 124
Query: 426 --XXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQP 599
+ KS+ + H +P + LVE+V T E + IG++P
Sbjct: 125 PITKLGACFSSAERKSRFVGMHFFSPAAIMKLVEVVNGEDTSAETVETACAFCTSIGKEP 184
Query: 600 VSLTREIDGFVLNRIQYAILDEVWRL 677
+ + + GFV+NRI AI DE RL
Sbjct: 185 IKV-NDCAGFVVNRILGAINDEAIRL 209
>UniRef50_Q6V1N6 Cluster: PlmT8; n=1; Streptomyces sp. HK803|Rep:
PlmT8 - Streptomyces sp. HK803
Length = 571
Score = 66.5 bits (155), Expect = 6e-10
Identities = 49/199 (24%), Positives = 84/199 (42%)
Frame = +3
Query: 66 SEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGE 245
+ +IG+VGSG + A A GY T+ + +A+ ++ L+ G L E
Sbjct: 290 ARRIGVVGSGTMATGIAQACARAGYPTTLVARSEVRAKEALATVENSLNRAVQRGRLTPE 349
Query: 246 LKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 425
+ + + + G + L AV V E V E++D+K+ VF+ LD+V T+
Sbjct: 350 -QLTSSMESLTGVSRL-EAVAACDLVVEAVVEDIDVKRTVFRELDAVCGAQTVLATSTSS 407
Query: 426 XXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVS 605
V+ H NP + LVE+V T E +G++PV
Sbjct: 408 LPVIECAMATGRPEAVVGMHFFNPAPVMKLVEVVRTALTSRETLGVAHATATALGKRPVG 467
Query: 606 LTREIDGFVLNRIQYAILD 662
+ GF++N + + L+
Sbjct: 468 CL-DRSGFIVNALLFPYLN 485
Score = 35.9 bits (79), Expect = 1.0
Identities = 31/134 (23%), Positives = 52/134 (38%), Gaps = 5/134 (3%)
Frame = +3
Query: 279 GSTDLATA---VKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXXE 449
G+ DL T + A V E VPE + K ++ + + +
Sbjct: 54 GTIDLTTRSADIVSADLVIEAVPERMKTKCELLSHAHNACAPGAVFATTTSGLAVTDIAF 113
Query: 450 GLKHKSQVIVSH--PVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREID 623
G + + H P P VE+V P T V + ++ ++GQ PVS+ +
Sbjct: 114 GSGRPCRTVGLHLFPQGPMDPATAVEVVGTPLTDGSVLADVQALIRDLGQVPVSVP-DRA 172
Query: 624 GFVLNRIQYAILDE 665
GFV + A L++
Sbjct: 173 GFVGGALTMAYLND 186
>UniRef50_Q876X5 Cluster: Dehydrogenase; n=7; Pezizomycotina|Rep:
Dehydrogenase - Fusarium sporotrichioides
Length = 285
Score = 66.5 bits (155), Expect = 6e-10
Identities = 58/200 (29%), Positives = 89/200 (44%), Gaps = 2/200 (1%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
+ ++G G++GR A +A+ GY V + D +Q A+E + D +RG ++A
Sbjct: 14 VAVLGGGVLGRRIACGWAASGYDVIIRDPSHEQRVAAVEYCNTSMSKYP-DSNVRGSIQA 72
Query: 255 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 434
E DL AV A V E VPE L +K F +L+ + ++TI
Sbjct: 73 VE---------DLPEAVAKAWLVIETVPEKLPIKIATFTDLERLTSEDTILCSNSSSYKS 123
Query: 435 XXXXEGLK--HKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
L+ K +V+ H PP Y +VE++ T + E +EEI P
Sbjct: 124 REMVGDLRPDTKRRVLNMHYYLPPDY-RVVELMTDGETDESIFPFLSEKLEEIRFHPYVA 182
Query: 609 TREIDGFVLNRIQYAILDEV 668
+E GF+ NR+ AI EV
Sbjct: 183 RKESTGFIYNRLWAAIKREV 202
>UniRef50_Q6KYW3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Picrophilus torridus|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Picrophilus torridus
Length = 273
Score = 66.1 bits (154), Expect = 8e-10
Identities = 50/200 (25%), Positives = 96/200 (48%), Gaps = 2/200 (1%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 251
++ ++G+G +G A +FA ++V + DV + + + I+ L + G ++
Sbjct: 2 RVTVIGAGTMGSGIAEVFALNNHEVLLSDVSNDILNNGRKKIEASLEKFKEKGRIKS--- 58
Query: 252 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNL--DSVVDDNTIXXXXXXX 425
+ + I +TD+ A + +++ E V E +D+K+ V + DS++ NT
Sbjct: 59 VEDVLEKISMNTDI-NAQESDLYI-EAVLERIDVKRDVLSRIRSDSIIATNT------SS 110
Query: 426 XXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVS 605
+ +++ + I H NPP + L+EIV T E K+ +I +G+ PV
Sbjct: 111 ISITYLSKFVRNPEKFIGMHFFNPPPIMSLIEIVRGNSTSDETTKRIVDISRSLGKTPVE 170
Query: 606 LTREIDGFVLNRIQYAILDE 665
+ + GFV NR+ A+L E
Sbjct: 171 V-NDFPGFVSNRVLMAMLRE 189
>UniRef50_A4SW21 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=1; Polynucleobacter sp.
QLW-P1DMWA-1|Rep: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor - Polynucleobacter sp.
QLW-P1DMWA-1
Length = 310
Score = 65.7 bits (153), Expect = 1e-09
Identities = 37/119 (31%), Positives = 61/119 (51%)
Frame = +3
Query: 321 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXXEGLKHKSQVIVSHPVNPP 500
V E V ENL LK+ +F +LD + + L ++ +H P
Sbjct: 79 VIESVSENLGLKRLIFSDLDQRLPSHIPIGSNTSGFPISDITASLPTAHRMFNTHYFMPA 138
Query: 501 YYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRL 677
+ VPLVE+V + PE+AK ++ + ++PV + ++I GF+ NRIQ+A++ EV L
Sbjct: 139 HIVPLVEVVLGKTSDPELAKTVCQLFQAHHKKPVLVKKDIPGFLANRIQHALMREVLSL 197
>UniRef50_P34439 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenase
F54C8.1; n=2; Caenorhabditis|Rep: Probable
3-hydroxyacyl-CoA dehydrogenase F54C8.1 - Caenorhabditis
elegans
Length = 298
Score = 65.7 bits (153), Expect = 1e-09
Identities = 52/206 (25%), Positives = 92/206 (44%), Gaps = 5/206 (2%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
+ IVGSG +G A + AS G+ V + DV K + A++ I + L +G K
Sbjct: 14 VAIVGSGQMGSGIAQVTASSGFNVMLADVNKKALDRAMKAISQSVTHLSKKQ--KGTDKE 71
Query: 255 SEQFQC-----IKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXX 419
F IK +++TAV A + E EN+DLK+ +F ++ ++I
Sbjct: 72 KSDFVTLTMSRIKTCNNVSTAVADADLIIEAAIENIDLKRGIFAQIEQSCKKDSILTTNT 131
Query: 420 XXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQP 599
+GL+ K++ H NP + L+E++ + T E + +G+
Sbjct: 132 SSFLLEDVAKGLQDKTRFGGLHFFNPVPVMKLLEVIRSDDTSDETYATLIKFGTAVGKTT 191
Query: 600 VSLTREIDGFVLNRIQYAILDEVWRL 677
V+ ++ GF++NR+ E R+
Sbjct: 192 VA-CKDSPGFIVNRLLIPYFFEAARM 216
>UniRef50_UPI00006A277A Cluster: UPI00006A277A related cluster; n=1;
Xenopus tropicalis|Rep: UPI00006A277A UniRef100 entry -
Xenopus tropicalis
Length = 666
Score = 65.3 bits (152), Expect = 1e-09
Identities = 51/198 (25%), Positives = 86/198 (43%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 251
K+GIVG+G +G AM FA+VG V +V + + + ++ G L E
Sbjct: 292 KVGIVGAGTMGGGIAMNFANVGIPTVVVEVNDETLQRGLGLVRRNYEASAAKGRLTAEQV 351
Query: 252 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 431
A + ++G+ D A A+ V E V EN+ LK+ + L +V I
Sbjct: 352 AG-RMALLQGALDYA-ALAECDLVIEAVFENMALKQDICAKLGAVAKPGAIIATNTSTLD 409
Query: 432 XXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLT 611
+ V+ H +P + + L+E+V T P+V ++ IG+ PV ++
Sbjct: 410 VDVLARATGRSADVVGMHFFSPAHVMRLLEVVRGAATAPDVLATIMKLAARIGKVPV-VS 468
Query: 612 REIDGFVLNRIQYAILDE 665
GF+ NR+ + E
Sbjct: 469 GVCYGFIGNRMAEVYMRE 486
>UniRef50_Q28UL9 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=3; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase NAD-binding - Jannaschia
sp. (strain CCS1)
Length = 687
Score = 65.3 bits (152), Expect = 1e-09
Identities = 54/193 (27%), Positives = 82/193 (42%), Gaps = 2/193 (1%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL- 248
KI IVG G +G A SVG V + + A DAI ++ + TL GL RG L
Sbjct: 284 KIAIVGGGTMGAGIAYACLSVGLPVVLLETDA----DAIARAQHNIDTLIGAGLKRGRLD 339
Query: 249 -KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 425
+ + T+ A A V E E++D+KK +F LD+ V +T+
Sbjct: 340 DSGAAALRDRLTLTEDYAAASDATLVIEAAFESMDVKKDIFAKLDAAVSPDTVLATNTSY 399
Query: 426 XXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVS 605
+ S+++ H P + + L+EIV T + + + + PV
Sbjct: 400 LDVDVLAASTRDPSRILGLHFFAPAHIMRLLEIVTGAETSDRALATGYALAKLLKKVPV- 458
Query: 606 LTREIDGFVLNRI 644
L DGF+ NRI
Sbjct: 459 LAGVCDGFIGNRI 471
>UniRef50_Q1YTH7 Cluster: Fatty oxidation complex, alpha subunit;
n=4; Gammaproteobacteria|Rep: Fatty oxidation complex,
alpha subunit - gamma proteobacterium HTCC2207
Length = 718
Score = 65.3 bits (152), Expect = 1e-09
Identities = 52/205 (25%), Positives = 91/205 (44%), Gaps = 1/205 (0%)
Frame = +3
Query: 48 MASKFKSEKI-GIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLEN 224
+ASK K G++G+G++G A A GY V + D+ + I++ L
Sbjct: 310 LASKLPEIKTAGVIGAGIMGGGIAYQNAIRGYSVVMKDINQPALDLGIQEANKLLAKGVK 369
Query: 225 DGLLRGELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 404
G L E KA + IK S + + + V E V E +KK V +++++D++ +
Sbjct: 370 RGKLTEE-KAGQILSLIKPSLEDSDVAPCNMLV-EAVVELESVKKMVLPAVEALLDNSAV 427
Query: 405 XXXXXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEE 584
E L+ H NP + +PLVEI+ T E
Sbjct: 428 ITSNTSTISINRLAESLERPQNFCGMHFFNPVHAMPLVEIIRGENTSDETIAAVCAYALG 487
Query: 585 IGQQPVSLTREIDGFVLNRIQYAIL 659
+G++P+ + + GF++NR+ +A+L
Sbjct: 488 LGKKPI-VVNDCPGFLVNRVLFAML 511
>UniRef50_A6WDS7 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=1; Kineococcus radiotolerans
SRS30216|Rep: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding - Kineococcus radiotolerans SRS30216
Length = 681
Score = 64.9 bits (151), Expect = 2e-09
Identities = 52/205 (25%), Positives = 92/205 (44%), Gaps = 1/205 (0%)
Frame = +3
Query: 63 KSEKIGIVGSGLIGRSWAMLFAS-VGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLR 239
K +G+VG+GL+ A+L + V + DV ++ + ++ + L G +
Sbjct: 317 KVTSVGVVGAGLMASQLALLLLHRLQVPVVLTDVSPDRVEKGVGFVREGVAELLRKGRVS 376
Query: 240 GELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXX 419
+ A+ + GS D +A+ A FV E V E L +K+ V + L+ ++ + +
Sbjct: 377 PDT-ANRLSASVSGSVD-KSALADADFVVEAVFEELAVKQDVLRELEPLLRPDAVIATNT 434
Query: 420 XXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQP 599
L+H + + H NP +PLVE+V P T E + T + ++
Sbjct: 435 SSLSVTAMASVLEHPQRFVGFHFFNPVAVLPLVEVVRTPET-DEASLATAFAVGARLKKT 493
Query: 600 VSLTREIDGFVLNRIQYAILDEVWR 674
L ++ FV+NRI + DEV R
Sbjct: 494 CVLVQDAPAFVVNRISTRMFDEVVR 518
>UniRef50_Q4J598 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD
binding domain; n=2; Azotobacter vinelandii|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD binding domain -
Azotobacter vinelandii AvOP
Length = 208
Score = 64.5 bits (150), Expect = 3e-09
Identities = 43/168 (25%), Positives = 80/168 (47%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
I I+GSG +G A A G++V + +Q+ + + + L L G E A
Sbjct: 6 IAILGSGSMGVGIATHLARHGHEVLLIYPSMEQLAEVLAMARSILAGLVEAGRFAPEQVA 65
Query: 255 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 434
+ + ++ ST L V G + E +PE ++LK+ ++ L+ +VD +
Sbjct: 66 ATLAR-LRTSTRLKD-VAGVRLLIETLPERIELKRALYAELERIVDAEAVIASDTGGLSP 123
Query: 435 XXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIM 578
EG++H +++++H +PP+ VPLV +V T+ E R ++
Sbjct: 124 ERLAEGMRHPGRLLIAHFRSPPHRVPLVAVVAGRQTRSEHLAYVRTLL 171
>UniRef50_Q1IMY8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Acidobacteria bacterium Ellin345|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Acidobacteria bacterium (strain Ellin345)
Length = 278
Score = 64.5 bits (150), Expect = 3e-09
Identities = 48/201 (23%), Positives = 90/201 (44%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
I ++G+G +GRS A A G++ + D++ + A + I+ +L + G + + +A
Sbjct: 7 IAVIGAGTMGRSIAQAAAVGGFRTILEDILPNALRKAEDAIRAELGRAVSTGSVE-QREA 65
Query: 255 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 434
I+ +++L A + A V E VP+ L+ K ++F LD V T+
Sbjct: 66 DAALARIEYASNLEDAARDADMVIEAVPDELESKLEIFVLLDKVCRPETMIVSHTQIQSI 125
Query: 435 XXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTR 614
+ + I PP +EIV T E A + + + ++P+ L R
Sbjct: 126 TELASVIYRAPKCIAMWFPKPPQTSVALEIVRGLETSDETATAAVAVAQRMKREPI-LLR 184
Query: 615 EIDGFVLNRIQYAILDEVWRL 677
E G + R+Q I +E +++
Sbjct: 185 ETPGAITARMQALISNEAFKM 205
>UniRef50_O29815 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 304
Score = 64.5 bits (150), Expect = 3e-09
Identities = 51/195 (26%), Positives = 88/195 (45%), Gaps = 3/195 (1%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIK---YQLHTLENDGLLR 239
EKIG+VG GL+G FA G +V DV +++ +E IK + L L G +
Sbjct: 3 EKIGVVGFGLMGTQITQFFAQQGLEVVAIDVSEERLRKGMEAIKAGRFGLQRLVEKGKIT 62
Query: 240 GELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXX 419
E + + I ST +A+K V E V E+++LK KV + +D+V D +
Sbjct: 63 EE-EMNAVLSRISTSTS-HSALKDCDLVIEAVFEDVNLKLKVLREIDAVTD--AVIGSNT 118
Query: 420 XXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQP 599
+ + + + H NP LVE+V + ++ R+ ++G+ P
Sbjct: 119 SSISITKLSSAVSNPERFLGIHFFNPAQIQKLVELVKGLLSDEKLVNGIRDWFLKLGKVP 178
Query: 600 VSLTREIDGFVLNRI 644
+ + + GF +R+
Sbjct: 179 I-VVNDSPGFATSRL 192
>UniRef50_Q83DW6 Cluster: Fatty oxidation complex, alpha subunit;
n=9; Gammaproteobacteria|Rep: Fatty oxidation complex,
alpha subunit - Coxiella burnetii
Length = 642
Score = 63.7 bits (148), Expect = 4e-09
Identities = 50/207 (24%), Positives = 99/207 (47%)
Frame = +3
Query: 54 SKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGL 233
+++ ++I ++G+G++G A A G +VT++D A++I AI+ + H L L
Sbjct: 269 TRYLPQQIHVIGAGVMGGDIAAWCALRGIRVTLHDKSAEKIAPAIK----RAHALYEKKL 324
Query: 234 LRGELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXX 413
L + + ++ + T VK A + E V E++ +K++V ++ + I
Sbjct: 325 KIPRLIQAAMDR-LEPDVE-GTGVKKADLIIEAVFEDIKVKQEVLSAIEPQLKPEAILAT 382
Query: 414 XXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQ 593
LK+ +++ H NP +PLVE+ + T ++A+K + I +
Sbjct: 383 NTSSLSLDELSSVLKNPERLVAIHFFNPVAKLPLVEVASSQQTSADIAEKALAFVGAIDK 442
Query: 594 QPVSLTREIDGFVLNRIQYAILDEVWR 674
P++++ GF++NR A L E R
Sbjct: 443 LPLAVSSS-PGFLVNRALMAYLLEANR 468
>UniRef50_Q4Q939 Cluster: Trifunctional enzyme alpha subunit,
mitochondrial-like protein; n=6; Trypanosomatidae|Rep:
Trifunctional enzyme alpha subunit, mitochondrial-like
protein - Leishmania major
Length = 726
Score = 63.7 bits (148), Expect = 4e-09
Identities = 46/205 (22%), Positives = 87/205 (42%), Gaps = 3/205 (1%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQL-HTLENDGLLRGEL 248
++G++G+G++G FA V V D+ + + I +++ + + ++ EL
Sbjct: 309 RVGVIGAGVMGSGIVHYFAKNNIPVAVKDLTEESVKQGITNVRAEFERAVRRKRMVTAEL 368
Query: 249 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNL--DSVVDDNTIXXXXXX 422
+ + G T + A + E E +D+KKKV Q L D ++ ++
Sbjct: 369 DG--KMALVTGGT-TNEVFRDADVIVEAAVEVMDIKKKVIQQLEKDGILHSKSLFATNTS 425
Query: 423 XXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPV 602
K ++ H NP +PLVE++ T E A + + G+ P+
Sbjct: 426 SLSLTEMQTVAKCPHNIVGMHFFNPVSKMPLVEVIKGKSTSTEAAAAIFNLALKTGKIPI 485
Query: 603 SLTREIDGFVLNRIQYAILDEVWRL 677
+ + GF++NRI + E RL
Sbjct: 486 -IVNDGPGFLVNRILGVYMAEAGRL 509
>UniRef50_A2QA05 Cluster: Catalytic activity:; n=4;
Trichocomaceae|Rep: Catalytic activity: - Aspergillus
niger
Length = 622
Score = 63.7 bits (148), Expect = 4e-09
Identities = 55/204 (26%), Positives = 86/204 (42%), Gaps = 2/204 (0%)
Frame = +3
Query: 63 KSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRG 242
KS I I+G+G++GR A +F+S GY V + D + A I +H + R
Sbjct: 13 KSRPIVIIGAGILGRRIAAVFSSAGYSVHISDPSPSALDSARTYISTHIHEFTTH-IPRP 71
Query: 243 ELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXX 422
L I T + AV A + E VPE L +K+ +F +L + + I
Sbjct: 72 SLSPGP----ISTFTSVPEAVATAWLIVEAVPEILPIKQSLFADLHAHSPADCILASNSS 127
Query: 423 XXXXXXXXEGLKHKSQVIV--SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQ 596
L +V++ H PP + VE++ T V ++ E G
Sbjct: 128 SYKSRLIGGHLPLPRRVLLLNMHFTMPP-AIRTVELMTCGDTHERVFPMLSGVLSECGVI 186
Query: 597 PVSLTREIDGFVLNRIQYAILDEV 668
PV+ +E GF+ NR+ AI E+
Sbjct: 187 PVTARKESTGFIFNRLWAAIKREI 210
>UniRef50_A1IFR8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Candidatus
Desulfococcus oleovorans Hxd3
Length = 304
Score = 63.3 bits (147), Expect = 6e-09
Identities = 44/198 (22%), Positives = 84/198 (42%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
+K+ I+G+G +G+ L A+ G++ +YD+ + A + ++ + L GE
Sbjct: 10 KKVLILGAGSMGQQIGFLCAAKGFETAIYDLSPPLLDTAKKRLEKLAGRFVSRHRLTGE- 68
Query: 249 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 428
+A+ + + D A A F+ E V E++++K +VF+ + I
Sbjct: 69 EAAAAMARVTLTPDSEQAAANADFISESVTESVEIKCRVFETFHPLCPARAIFTTNTSSL 128
Query: 429 XXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
+ + H N +V+I+P P T PE A+ R +GQ P+
Sbjct: 129 IPSMLTHAVGRPDRFAAFHFHNT-LTSDIVDIMPHPGTTPETAETIRAFALRLGQVPIVF 187
Query: 609 TREIDGFVLNRIQYAILD 662
+E G+ N + + D
Sbjct: 188 KKENHGYAFNALLMNLCD 205
>UniRef50_A4RUY4 Cluster: Predicted protein; n=5; cellular
organisms|Rep: Predicted protein - Ostreococcus
lucimarinus CCE9901
Length = 722
Score = 63.3 bits (147), Expect = 6e-09
Identities = 47/193 (24%), Positives = 88/193 (45%), Gaps = 1/193 (0%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
+ +G+VG GL+G A G QV + ++ + + + I+ L ++ G + E
Sbjct: 305 KSVGVVGGGLMGSGIATACLLAGIQVVLKEIKQEFLDAGVGRIQSNLTSMVRKGRMT-ED 363
Query: 249 KASEQFQCIKGS-TDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 425
KA + +K + TD + V E V ENL LK+K+F L+ + + I
Sbjct: 364 KARQLMSLVKPTLTD--QDFRQCDMVIEAVIENLPLKQKIFCELERICKPDCILSTNTST 421
Query: 426 XXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVS 605
+K+ +++ +H +P + + L EI+ T ++ T + ++I + PV
Sbjct: 422 IDITKIAAKMKNPERIVGAHFFSPAHVMQLFEIIRTDATPAQILVDTLGLSKQIKKTPV- 480
Query: 606 LTREIDGFVLNRI 644
+ GF +NRI
Sbjct: 481 VVGNCTGFAVNRI 493
>UniRef50_Q392L7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=9;
Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 336
Score = 62.5 bits (145), Expect = 1e-08
Identities = 54/218 (24%), Positives = 93/218 (42%), Gaps = 8/218 (3%)
Frame = +3
Query: 48 MASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQIT--DAIED-----IKYQ 206
M++ + +I ++G+G +G+ A++FA G VT+ D + A +D I
Sbjct: 1 MSAAAEVTRIHVLGAGRMGQGIALVFAFAGIDVTLIDFKRRDAVGQSAFDDRTRDEIARP 60
Query: 207 LHTLENDGLL-RGELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDS 383
LH G + + A I A AV+ A V E +PE LD K + L
Sbjct: 61 LHAQVALGRIDAAQADAVVARIAIVARDGAAEAVRDADIVFEALPEVLDAKADALRWLGE 120
Query: 384 VVDDNTIXXXXXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKK 563
VD + +++ +H +NP +PLVEI + T V
Sbjct: 121 HVDARATIASTTSTFVVTELQRHVVRPERMLNAHWLNPALLMPLVEISRSDATDQSVVDA 180
Query: 564 TREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRL 677
++E +G++PV + G+++ RIQ ++E R+
Sbjct: 181 LAALLERVGKKPV-ICGPAPGYIVPRIQALAMNEAARM 217
>UniRef50_A0QZQ9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Mycobacterium smegmatis str. MC2 155|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Mycobacterium
smegmatis (strain ATCC 700084 / mc(2)155)
Length = 293
Score = 62.1 bits (144), Expect = 1e-08
Identities = 51/198 (25%), Positives = 85/198 (42%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
+G++G G +G +FA+ G V V + +I + I L T G L E
Sbjct: 11 VGVLGLGTMGAGITQVFAASGRDVVVLEADQDRIDAGLASISAFLDTGVAKGKL-SETDK 69
Query: 255 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 434
S I +TD+ T + V E V EN ++KK + + +VV NT
Sbjct: 70 SGLLARITATTDV-TDLADVDLVVESVTENAEVKKDLLGRVAAVVGVNTPICTNTSALSV 128
Query: 435 XXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTR 614
L + S+V H NP VE+V A T E+ + +++ +G + + +
Sbjct: 129 TELAAALPNPSRVAGLHFFNPAPLQRTVEVVRALQTGEELVDRLVALVDTLGNKDPIVVK 188
Query: 615 EIDGFVLNRIQYAILDEV 668
+ GF+LN + L++V
Sbjct: 189 DRPGFLLNALLLPYLNDV 206
>UniRef50_Q5KBI5 Cluster: Short chain 3-hydroxyacyl-CoA
dehydrogenase, putative; n=1; Filobasidiella
neoformans|Rep: Short chain 3-hydroxyacyl-CoA
dehydrogenase, putative - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 342
Score = 62.1 bits (144), Expect = 1e-08
Identities = 51/209 (24%), Positives = 94/209 (44%), Gaps = 4/209 (1%)
Frame = +3
Query: 63 KSEKIGIVGSGLIGRSWAMLFASVGYQVTVYD--VVAKQITDAIEDIKYQLHTLENDGLL 236
K E++ + G+GL+G A + A G +V + D + + + I ++ ++ +
Sbjct: 35 KVEELTVFGAGLMGAGIAQVGAQNGLKVELTDDPAILRNGINIISKSLARVAKKKSPDDI 94
Query: 237 RGELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXX 416
G + + I +TD + AV+ A V E + E++ +K+ +F LD + I
Sbjct: 95 EGF--TNNVLKNISTTTDSSQAVENADLVVEAIIESIKVKRDLFGFLDGKAKSDCIFATN 152
Query: 417 XXXXXXXXXXEGLKHKSQVIVS--HPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIG 590
E + Q + H NP + LVEI+ P T E + RE+ ++G
Sbjct: 153 TSSLSVTEIAEACSPERQAKFAGLHFFNPVPAMKLVEIIRTPQTSQETYETLREVTLQMG 212
Query: 591 QQPVSLTREIDGFVLNRIQYAILDEVWRL 677
+ PV+ + GF++NR+ L E R+
Sbjct: 213 KSPVT-CNDTPGFIVNRLLVPYLLEAIRM 240
>UniRef50_Q45223 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=92;
cellular organisms|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Bradyrhizobium japonicum
Length = 293
Score = 62.1 bits (144), Expect = 1e-08
Identities = 42/199 (21%), Positives = 89/199 (44%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
+K+G++G+G +G A + A G+ V + DV A ++ + I L + ++ E
Sbjct: 6 KKVGVIGAGQMGNGIAHVAALAGFDVVLNDVSADRLKSGMATINGNLARQVSKKVVTEEA 65
Query: 249 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 428
K + + + + + V E E ++K+K+F L +V+ I
Sbjct: 66 KTKALSRIV--AAEKLDDLADCDLVIETAVEKEEVKRKIFHELCAVLKPEAIVASDTSSI 123
Query: 429 XXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
+ I H +NP + LVE++ T + ++E + ++G+Q V++
Sbjct: 124 SITRLAAATDRPERFIGIHFMNPVPLMELVELIRGIATDDATFEASKEFVAKLGKQ-VAV 182
Query: 609 TREIDGFVLNRIQYAILDE 665
+ + F++NRI +++E
Sbjct: 183 SEDFPAFIVNRILLPMINE 201
>UniRef50_Q8KUG1 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=8;
Actinomycetales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Actinosynnema pretiosum subsp. auranticum
Length = 341
Score = 61.7 bits (143), Expect = 2e-08
Identities = 46/199 (23%), Positives = 85/199 (42%)
Frame = +3
Query: 81 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKASE 260
++G+G++G L S G V + D A ++ A D++ L T + G+ G L
Sbjct: 62 VLGAGVMGCGITALALSRGLPVLLVDPDADRLDAARADVRAHLRTAQLLGVAAGPLGE-- 119
Query: 261 QFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXX 440
+ +TD + V V E V E+ + K K + + V T
Sbjct: 120 ----LTTATDTG-GPREVVAVVEAVTEDAETKAKALTGVCATVPPGTPLVSNTSSIPMGE 174
Query: 441 XXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREI 620
L ++ +H +NPPY +P VE+ P T ++ +G+ PV + +
Sbjct: 175 LAPALPRPGDLVGAHFMNPPYLIPAVEVARGPLTSDAAFAGLTALLARLGRAPVQV-GDA 233
Query: 621 DGFVLNRIQYAILDEVWRL 677
GFV +R+ + ++++ R+
Sbjct: 234 PGFVTSRLLHPMINDAARV 252
>UniRef50_Q6D2L7 Cluster: Fatty acid oxidation complex subunit alpha
[Includes: Enoyl-CoA hydratase/3-hydroxybutyryl-CoA
epimerase (EC 4.2.1.17) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)]; n=16;
Gammaproteobacteria|Rep: Fatty acid oxidation complex
subunit alpha [Includes: Enoyl-CoA
hydratase/3-hydroxybutyryl-CoA epimerase (EC 4.2.1.17)
(EC 5.1.2.3); 3-hydroxyacyl-CoA dehydrogenase (EC
1.1.1.35)] - Erwinia carotovora subsp. atroseptica
(Pectobacterium atrosepticum)
Length = 731
Score = 61.7 bits (143), Expect = 2e-08
Identities = 51/199 (25%), Positives = 87/199 (43%), Gaps = 1/199 (0%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGY-QVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
++GI+G GL+G A + A+ G V + D+ + I A++ +QL T
Sbjct: 324 RVGILGGGLMGGGIASVTATRGQLPVRIKDINEQGINHALK-YNWQLLTKRVQSKRMKPT 382
Query: 249 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 428
+ I GSTD + A V E V E+L LK+++ ++ +TI
Sbjct: 383 ERQRLMTLISGSTDYR-GFEHADIVIEAVFEDLALKRQMITEIEDHAAPHTIFASNTSSL 441
Query: 429 XXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
EG + V+ H +P +PLVE++P T E T + + G+ + +
Sbjct: 442 PIHQIAEGARRPQLVVGLHYFSPVDKMPLVEVIPHAHTSAETVATTVALARKQGKTAI-V 500
Query: 609 TREIDGFVLNRIQYAILDE 665
+ GF +NRI ++E
Sbjct: 501 VGDSAGFYVNRILAPYINE 519
>UniRef50_Q9RUA4 Cluster: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA
isomerase/3-hydroxyacyl-CoA dehydrogenase; n=18;
Bacteria|Rep: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA
isomerase/3-hydroxyacyl-CoA dehydrogenase - Deinococcus
radiodurans
Length = 708
Score = 61.3 bits (142), Expect = 2e-08
Identities = 51/200 (25%), Positives = 83/200 (41%)
Frame = +3
Query: 78 GIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKAS 257
GI+G+G +G AM F +VG VT+ + + + + I+ G + +
Sbjct: 311 GIIGAGTMGGGIAMNFLNVGIPVTIVETSQEALDRGLGVIRKNYENTAKKGRMTQD--DV 368
Query: 258 EQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXX 437
E+ + T + GA + E V EN+D+KK +F LD + I
Sbjct: 369 EKRMGLLTPTLKMEDLAGADIIIEAVFENMDVKKDIFTRLDKIAKPGAILASNTSTLDVN 428
Query: 438 XXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTRE 617
QVI H +P + L+EIV A T V + + + I + V +
Sbjct: 429 EIASVTGRPEQVIGLHFFSPANVMKLLEIVRADKTSDSVLATSLALAKRIKKVGV-VVGV 487
Query: 618 IDGFVLNRIQYAILDEVWRL 677
DGFV NR+ + DE ++
Sbjct: 488 CDGFVGNRMVHRYGDEARKI 507
>UniRef50_Q5LKF7 Cluster: Fatty oxidation complex, alpha subunit;
n=5; Bacteria|Rep: Fatty oxidation complex, alpha
subunit - Silicibacter pomeroyi
Length = 714
Score = 61.3 bits (142), Expect = 2e-08
Identities = 47/195 (24%), Positives = 86/195 (44%), Gaps = 2/195 (1%)
Frame = +3
Query: 63 KSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRG 242
K +++GI+G+G++G+ A A+ G V + D Q +A E K TL + + +G
Sbjct: 316 KVQRLGILGAGMMGQGIAFSAATAGLPVVLKD----QTLEAAERGKAYTATLLDKRVKQG 371
Query: 243 ELKASEQFQCIK--GSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXX 416
+ A E+ + TD A +KG + E V E +D+K V ++++ +N I
Sbjct: 372 RMSAEEREAVLALITPTDKADDLKGCDLIIEAVFEKIDIKDAVLAEHEALLAENGIWGSN 431
Query: 417 XXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQ 596
G + H +P +PL+EI+ T E + + +I +
Sbjct: 432 TSTLPITRLATGATRPENFVGLHFFSPVDKMPLLEIIAGEKTSDETLARAFDFARQIRKT 491
Query: 597 PVSLTREIDGFVLNR 641
P+ + + GF +R
Sbjct: 492 PI-IVGDSTGFYTSR 505
>UniRef50_Q1ISD6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Acidobacteria bacterium Ellin345|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Acidobacteria bacterium (strain Ellin345)
Length = 293
Score = 61.3 bits (142), Expect = 2e-08
Identities = 43/192 (22%), Positives = 82/192 (42%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
+ +G++G GL+G A A+ G+ V V + + + ++ L G +
Sbjct: 4 KSVGVIGCGLMGSGIAQAAATAGFPVIVLEAEQRFLDRGFTGVERSLAKFAEKGTITESP 63
Query: 249 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 428
A +KG+T++ + + E + EN+ K K++ L+ V + I
Sbjct: 64 DAIRAR--LKGTTNVEDLADCDIII-EAILENVPEKHKMYAALEKVAKPDAIFASNTSSI 120
Query: 429 XXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
K + I H NP + LVE++ T EV + + ++G+ PV
Sbjct: 121 SITELMAATKRPERFIGLHFFNPVPLMKLVEVIRTIATSDEVFEAAVDFGTKLGKVPVR- 179
Query: 609 TREIDGFVLNRI 644
T++ GF++NR+
Sbjct: 180 TKDSSGFIVNRL 191
>UniRef50_Q0SCS0 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2;
Actinomycetales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Rhodococcus sp. (strain RHA1)
Length = 284
Score = 61.3 bits (142), Expect = 2e-08
Identities = 49/192 (25%), Positives = 82/192 (42%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
+ +G+VG G +G A +FA++G V + + ++ A++ + L G L G++
Sbjct: 7 KNVGVVGGGRMGAGIAQVFATLGSTVIIAESGDREA--AVKRVSDGLDRAHERGKL-GDV 63
Query: 249 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 428
+ + V E VPE +DLK V ++ V T+
Sbjct: 64 DPATILGRVSTVAAPDALPPALDLVVEAVPELVDLKLSVLSLVEKTVSPTTVIASNTSSI 123
Query: 429 XXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
L +++I H NP LVEIV AP T V +K RE + ++G+ V L
Sbjct: 124 SIAELGSALGDPARLIGMHFFNPVPASSLVEIVRAPATDAGVVEKVREWVAQLGKTEV-L 182
Query: 609 TREIDGFVLNRI 644
+ GF +R+
Sbjct: 183 VNDSPGFATSRL 194
>UniRef50_A3ZZK1 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1;
Blastopirellula marina DSM 3645|Rep:
3-hydroxybutyryl-coA dehydrogenase - Blastopirellula
marina DSM 3645
Length = 319
Score = 61.3 bits (142), Expect = 2e-08
Identities = 44/203 (21%), Positives = 86/203 (42%), Gaps = 2/203 (0%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
+G+VG GL+GR + +QV YD+ + A + L L + +
Sbjct: 6 VGVVGLGLMGRGICTSLLANNFQVVAYDINPESFAAARAHVASALEELARHPSVAEAIPE 65
Query: 255 S--EQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 428
+ FQ + DL+ + FV E +PE+ +K++ L+ ++ ++T
Sbjct: 66 NWPSHFQL---TADLSP-LGDCDFVIESIPEDPVIKQETIAALERLLPNSTPIASNTSAL 121
Query: 429 XXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
+ ++I H P + +EI+ T A + ++G+ P +
Sbjct: 122 PISLLQAHCQLPQRIIGMHWAEPCHLTRFLEIIRGEHTDDATADSAANLGRQLGKDPTIV 181
Query: 609 TREIDGFVLNRIQYAILDEVWRL 677
R++ GF++NR+ YA+ E + L
Sbjct: 182 QRDVPGFIVNRLAYAMYREAFWL 204
>UniRef50_A1B712 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=2; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Paracoccus denitrificans (strain Pd 1222)
Length = 765
Score = 61.3 bits (142), Expect = 2e-08
Identities = 51/197 (25%), Positives = 93/197 (47%), Gaps = 5/197 (2%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
EK+ ++G+G++G A A+ G +V + DV K DA + ++G G +
Sbjct: 6 EKVAVLGAGVMGAGIAAHLANAGVRVVLLDV-DKAAADA------GIRRARDEG---GFM 55
Query: 249 KASEQFQCIKGST--DLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXX 422
+ + GST DL+ + A ++ E +PE L LK+ +++ L + +I
Sbjct: 56 DPAFAARIATGSTVRDLSL-LADADWIVEALPERLALKQSLYRQLQGIRKPGSILSSNTS 114
Query: 423 XXXXXXXXEGLK--HKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEE-IGQ 593
G+ + +++H NPP + L+E+V P T+PE+ + + +G+
Sbjct: 115 TIPLAALVGGMAGDFAADFLITHFFNPPRRMRLLELVAGPATRPEIVALITDFCDRRLGK 174
Query: 594 QPVSLTREIDGFVLNRI 644
VS R+ GF+ NRI
Sbjct: 175 DVVSC-RDTPGFIANRI 190
>UniRef50_Q2S2J8 Cluster: Fatty oxidation complex, alpha subunit;
n=2; Bacteria|Rep: Fatty oxidation complex, alpha
subunit - Salinibacter ruber (strain DSM 13855)
Length = 719
Score = 60.9 bits (141), Expect = 3e-08
Identities = 49/199 (24%), Positives = 87/199 (43%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
+ +G++G+GL+G A + A G V + D + + I + E+ G++
Sbjct: 319 DTVGVLGAGLMGSGIAQVSAQNGLDVVLTDQSLALAAEGKKAIWSAVTEQEDKGIIN-TF 377
Query: 249 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 428
+ + + + D A ++ A V E VPE+L +K V +++VVD +T+
Sbjct: 378 TRDQIVERVAPTADYAP-LQAADVVIEAVPEDLSIKHAVLSEVETVVDADTVLASNTSAL 436
Query: 429 XXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
EG+ S+V+ H +P +PL+EIV T E A T + V +
Sbjct: 437 PISTIAEGVDDPSRVLGMHYFSPVPDIPLLEIVVTEETSDE-ALATAYAAGLAQDKTVIV 495
Query: 609 TREIDGFVLNRIQYAILDE 665
+ GF RI ++E
Sbjct: 496 VNDGPGFYTTRILALYMNE 514
>UniRef50_Q14G85 Cluster: Fusion product of 3-hydroxacyl-CoA
dehydrogenase and acyl-CoA-binding protein; n=11;
Francisella tularensis|Rep: Fusion product of
3-hydroxacyl-CoA dehydrogenase and acyl-CoA-binding
protein - Francisella tularensis subsp. tularensis
(strain FSC 198)
Length = 898
Score = 60.9 bits (141), Expect = 3e-08
Identities = 47/196 (23%), Positives = 85/196 (43%), Gaps = 4/196 (2%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQ--ITDAIEDIKYQLHTLENDGLLRG 242
+KI ++G+G +G A FA+ + V ++D+ ++Q IED +L L G
Sbjct: 118 DKIAVLGAGTMGAQIAAHFANAKFPVVLFDLKSQQGSANVIIEDSLAKLTKLNPAPF--G 175
Query: 243 ELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXX 422
K S ++ D + + E V E +D+K+ ++ + S + +N I
Sbjct: 176 S-KDSIKYITPANYEDNLELLADCDLIIEAVAERIDIKESLYTKISSHIKENAILASNTS 234
Query: 423 XXXXXXXXEGLKHKSQVIVS--HPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQ 596
+ L +V H NPP Y+PLVE++P T E+ K + E +
Sbjct: 235 GLSITKLAQVLPENLKVNFCGVHFFNPPRYMPLVELIPHADTNSEILDKLETFLVEKLGK 294
Query: 597 PVSLTREIDGFVLNRI 644
+ ++ F+ NR+
Sbjct: 295 SIIRAKDTPNFIANRL 310
>UniRef50_Q9HJM0 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase
related protein; n=3; Thermoplasmatales|Rep:
Beta-hydroxybutyryl-CoA dehydrogenase related protein -
Thermoplasma acidophilum
Length = 314
Score = 60.9 bits (141), Expect = 3e-08
Identities = 57/230 (24%), Positives = 100/230 (43%), Gaps = 34/230 (14%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDV---VAKQITDAIEDIKYQLHTLENDGLLRGE 245
+G++G+G +G + A LFA G+ V + D +A+ IE I + + ND E
Sbjct: 6 VGVIGAGTMGSAIAELFAFNGFNVVMKDQNMDLARSGYSGIEKILNDMKRI-NDEKPEKE 64
Query: 246 LKASEQFQCIKGSTDLATAVKGAVFVQ--------------------------ECVPENL 347
+ E + IK S D A++ + VQ E EN
Sbjct: 65 IARIENYG-IKLSDDQKNAIRKKIGVQVDVNAMLKRISLTDKYSDLSSCDLVIEAAFENQ 123
Query: 348 DLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIV 527
D+K ++F ++ S + ++ I LK ++ H NPPY +PLVE+V
Sbjct: 124 DVKNRIFSDI-SDLSEHAIIASNTSSLSITEMSSRLKRPENALILHFFNPPYLLPLVEVV 182
Query: 528 PAPWTKPEVAKKTREIMEEI-----GQQPVSLTREIDGFVLNRIQYAILD 662
P+ +T E ++ + G PV + +E +GF++NR+ +++
Sbjct: 183 PSLYTSDEAKNTAVSLISRMKNHREGMVPV-MAKEREGFIVNRLLIPLIN 231
>UniRef50_Q8W1L6 Cluster: Peroxisomal fatty acid beta-oxidation
multifunctional protein (MFP) [Includes: Enoyl-CoA
hydratase/3-2-trans-enoyl-CoA isomerase/3-
hydroxybutyryl-CoA epimerase (EC 4.2.1.17) (EC 5.3.3.8)
(EC 5.1.2.3); 3-hydroxyacyl-CoA dehydrogenase (EC
1.1.1.35)]; n=23; Magnoliophyta|Rep: Peroxisomal fatty
acid beta-oxidation multifunctional protein (MFP)
[Includes: Enoyl-CoA hydratase/3-2-trans-enoyl-CoA
isomerase/3- hydroxybutyryl-CoA epimerase (EC 4.2.1.17)
(EC 5.3.3.8) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)] - Oryza sativa subsp.
japonica (Rice)
Length = 726
Score = 60.9 bits (141), Expect = 3e-08
Identities = 50/213 (23%), Positives = 88/213 (41%)
Frame = +3
Query: 3 FTRGLSCGTVASTVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITD 182
F + L+ T + K K+ ++G GL+G A V + +V + +
Sbjct: 288 FAQRLTTKVPGVTDVQLKPRKIRKVAVIGGGLMGSGIATALLVSNTSVVLKEVNPQFLQR 347
Query: 183 AIEDIKYQLHTLENDGLLRGELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKK 362
+ I L L G L + K ++ +KG+ D + K V E V E + LK+
Sbjct: 348 GQKMIAANLEGLVKRGSLTKD-KMNKAMSLLKGALDYSD-FKDVDMVIEAVIEKIPLKQS 405
Query: 363 VFQNLDSVVDDNTIXXXXXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWT 542
+F +L+ V + I E + ++I +H +P + +PL+EIV T
Sbjct: 406 IFSDLEKVCPPHCILATNTSTIDLNVVGEKTNSQDRIIGAHFFSPAHIMPLLEIVRTEKT 465
Query: 543 KPEVAKKTREIMEEIGQQPVSLTREIDGFVLNR 641
P+ + + I + PV + GF +NR
Sbjct: 466 SPQAILDLITVGKMIKKVPV-VVGNCTGFAVNR 497
>UniRef50_Q5LVG3 Cluster: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase;
n=2; Rhodobacteraceae|Rep: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase -
Silicibacter pomeroyi
Length = 681
Score = 60.5 bits (140), Expect = 4e-08
Identities = 53/193 (27%), Positives = 86/193 (44%), Gaps = 2/193 (1%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 251
++ IVG GL+G AM G VTV + A A E + L G+ RG++
Sbjct: 288 RVAIVGGGLMGAGVAMACLGGGLSVTVIERDAAAAQAAQERVA----GLVAAGVKRGKIS 343
Query: 252 ASEQFQCIK--GSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 425
Q + +TD A E V E+LD+K+ VF +L +V+ + I
Sbjct: 344 PDAQADMLARLATTDTYADASDADLAIEAVFEDLDVKRIVFADLAAVMRPDAILATNTSY 403
Query: 426 XXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVS 605
G+ + ++ + H +P + + L+EIV P T PEV + + + + V
Sbjct: 404 LDPQLVFAGIANPARCLGLHFFSPAHVMKLLEIVKTPDTAPEVLATGFALGKRLRKISV- 462
Query: 606 LTREIDGFVLNRI 644
L+ DGF+ NR+
Sbjct: 463 LSGICDGFIGNRM 475
>UniRef50_Q2J6P6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=10;
Actinomycetales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Frankia sp. (strain CcI3)
Length = 624
Score = 60.5 bits (140), Expect = 4e-08
Identities = 46/205 (22%), Positives = 86/205 (41%)
Frame = +3
Query: 63 KSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRG 242
+ ++G+VG G +G A + A G +V A + + +++ L G L
Sbjct: 37 RHRRVGVVGLGTMGAGIAEVLAKAGLEVVGIARDADALARSRARVEHSLDRAGRHGKLDD 96
Query: 243 ELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXX 422
+ + + G T+LA AV V E + E + K+ +F LD + T+
Sbjct: 97 ATREAVLARMRLG-TELA-AVADCELVIEAIDERMSAKQALFARLDEICPPATVFLTNTS 154
Query: 423 XXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPV 602
G +V+ +H NP + LVE+V T P V ++ ++G+ V
Sbjct: 155 SLSVTELAAGTARPERVLGTHWFNPAPVMRLVEVVRTVVTDPTVLAGVIGLVNDVGKTAV 214
Query: 603 SLTREIDGFVLNRIQYAILDEVWRL 677
+ + GF++N + + L+ R+
Sbjct: 215 -VAEDRAGFIVNALLFGYLNNAVRM 238
Score = 58.8 bits (136), Expect = 1e-07
Identities = 45/204 (22%), Positives = 87/204 (42%), Gaps = 3/204 (1%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
+G+VGSG + A + A G+ V + + + + I+ L + RG L
Sbjct: 345 VGVVGSGTMAGGIAEVLARSGHDVLLRARSERTLAATLAKIESSLAA----SVARGRLSD 400
Query: 255 SEQFQC---IKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 425
+++ ++G+TDL + + E V E+L +K+++F +LD + +
Sbjct: 401 ADRLAALARVRGTTDLGE-LGHCELLLEAVVEDLAVKRELFADLDKIAAPGAVLATTTSS 459
Query: 426 XXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVS 605
VI H NP + L+E+VP T +V + G+ PV
Sbjct: 460 LPVIECAMATSRPRDVIGMHWFNPAPAMKLIEVVPTVLTGDDVTATVLALSRAAGRHPV- 518
Query: 606 LTREIDGFVLNRIQYAILDEVWRL 677
L + GF++N + + L++ ++
Sbjct: 519 LCADRAGFIVNALLFPYLNDAVKM 542
>UniRef50_Q0FMY4 Cluster: Enoyl-CoA hydratase; n=1; Roseovarius sp.
HTCC2601|Rep: Enoyl-CoA hydratase - Roseovarius sp.
HTCC2601
Length = 634
Score = 60.5 bits (140), Expect = 4e-08
Identities = 54/202 (26%), Positives = 82/202 (40%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 251
+ +VG+ G AM FA G V + D A QI A I + G + G
Sbjct: 293 RAAVVGADSAGAGIAMCFARAGLPVVLIDTDAAQIERARARIAELWDQARDGGGIDGPTL 352
Query: 252 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 431
+++ + ++ ST+L A V V V E++ +++F LD + I
Sbjct: 353 VAQRAR-LELSTELHAAASADVVVA-AVSEDMTQTQEIFSALDRICKPGAILVNNGATLD 410
Query: 432 XXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLT 611
+ + VI H + P V L+E+V T PEV + + +QPV L
Sbjct: 411 LDSIAQATRRPGDVIGMHFLQPDGAVRLLEVVRGARTAPEVIATVMALAPRLDKQPV-LV 469
Query: 612 REIDGFVLNRIQYAILDEVWRL 677
DG V NR+ A EV L
Sbjct: 470 GVCDGLVGNRMVRAFGREVQML 491
>UniRef50_A1WHE6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Verminephrobacter eiseniae EF01-2|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Verminephrobacter eiseniae (strain
EF01-2)
Length = 319
Score = 60.5 bits (140), Expect = 4e-08
Identities = 44/186 (23%), Positives = 75/186 (40%)
Frame = +3
Query: 81 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKASE 260
++G+G++G + A G V VYD+ + + + + D + E +
Sbjct: 9 VLGAGVLGGQISWHSAFKGKSVVVYDISEEALARCRAAQAHYAAIYQTDAVGASEADVAG 68
Query: 261 QFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXX 440
Q + +TDLA+AV A V E VPE +K V+Q + ++ +T+
Sbjct: 69 ARQRLTFATDLASAVASADLVIEAVPEIPQVKTSVYQQMAPLLPAHTLIATNSSTFLPSD 128
Query: 441 XXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREI 620
+ H N + LVEI+P T E G P+ + +E
Sbjct: 129 FAAATGRPDKFCALHYANYIWAANLVEIMPHAATARTTLDDVTRFAIETGMVPIPVGKEH 188
Query: 621 DGFVLN 638
+G+VLN
Sbjct: 189 NGYVLN 194
>UniRef50_A1SQH4 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=104; cellular organisms|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Nocardioides sp. (strain BAA-499 / JS614)
Length = 736
Score = 60.5 bits (140), Expect = 4e-08
Identities = 48/198 (24%), Positives = 89/198 (44%), Gaps = 3/198 (1%)
Frame = +3
Query: 60 FKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLR 239
+++ K+G++G+G++G A A G +V + DV ++ E K L + + +
Sbjct: 322 YRAVKVGVLGAGMMGAGIAYSCARSGMEVVLKDVAV----ESAEKGKAYSEKLLDKAIAK 377
Query: 240 G---ELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXX 410
G E K +E I + D A + G V E V E+ LK++VF + VD + +
Sbjct: 378 GRSTEEKKAELLGRITATADAAD-LAGCDLVIEAVFEDPSLKQQVFAEIAPYVDQDALLC 436
Query: 411 XXXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIG 590
G+ + I H +P +PLVEI+ T K +++++I
Sbjct: 437 SNTSTLPITELASGVDRPADFIGLHFFSPVDKMPLVEIIRGAKTSDVALAKAYDVVQQIR 496
Query: 591 QQPVSLTREIDGFVLNRI 644
+ P+ + + GF +R+
Sbjct: 497 KTPI-VVNDSRGFYTSRV 513
>UniRef50_Q2SGN8 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Hahella chejuensis KCTC 2396|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Hahella chejuensis (strain KCTC 2396)
Length = 283
Score = 60.1 bits (139), Expect = 5e-08
Identities = 53/204 (25%), Positives = 94/204 (46%), Gaps = 7/204 (3%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDG-------L 233
I ++G G IG S A A G+ V VV ++ + E + ++ LE G L
Sbjct: 6 IAVIGGGNIGSSLAFDCALRGHNV----VVVEKDEPSCEQSRARV--LETAGYAPLFSPL 59
Query: 234 LRGELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXX 413
+G+ K + I+ S +L A+ FV E +PEN++LK+ ++ + + N +
Sbjct: 60 AKGK-KPQDILDNIRWSNELG-AISDCAFVVENIPENIELKQALYTRMAEFIAPNAVLAA 117
Query: 414 XXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQ 593
K +QVI H +NP Y VE++ T + + E++ +G+
Sbjct: 118 NTSCIPITKLGSFHKTSAQVIGVHFMNPVYLKHTVEVILGLNTSEQTKDRCLEMLAMLGK 177
Query: 594 QPVSLTREIDGFVLNRIQYAILDE 665
+ V + ++ GFV NRI + ++E
Sbjct: 178 KAV-VVKDGPGFVSNRISHLFMNE 200
>UniRef50_Q06BB6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Vibrio cholerae|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Vibrio cholerae
Length = 284
Score = 60.1 bits (139), Expect = 5e-08
Identities = 38/137 (27%), Positives = 63/137 (45%)
Frame = +3
Query: 255 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 434
SE ++ ++D + A+K A V E V E+ D+K + + +VVDD TI
Sbjct: 67 SESMAALQITSDFS-ALKSAELVIEAVSEDKDVKHDIMAKIAAVVDDTTIVASNTSSLSI 125
Query: 435 XXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTR 614
+ + H NP + LVE+V T + +K IG++PV +
Sbjct: 126 TELAANFRKPENFLGLHFFNPAPMMSLVEVVRGLTTCESIIEKAVVFSRSIGKEPV-VVN 184
Query: 615 EIDGFVLNRIQYAILDE 665
E GFV+NR+ +++E
Sbjct: 185 EAPGFVVNRMLIPMINE 201
>UniRef50_A1SXV8 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Psychromonas|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Psychromonas ingrahamii
(strain 37)
Length = 724
Score = 60.1 bits (139), Expect = 5e-08
Identities = 45/195 (23%), Positives = 83/195 (42%)
Frame = +3
Query: 81 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKASE 260
++G+G++G A LF+ V + D+ ++ + L+ + E K
Sbjct: 329 VLGAGVMGGGIAWLFSKNEIPVRLKDIEWDAVSKGYQTAALYYGQLKKVHKIN-ENKIRV 387
Query: 261 QFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXX 440
+ I G+ + K V E V ENL++KK V + +++ + I
Sbjct: 388 KMNYIAGTVNY-NGFKRIDLVVEAVSENLEVKKTVLEEVEAQLSKQAILASNTSSLSITE 446
Query: 441 XXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREI 620
L+ I H NP +PLVEI+P T + ++ ++ G+ P+ +
Sbjct: 447 MAVNLQRPENFIGMHFFNPVNRMPLVEIIPGEKTSQQTIVTLVKLAKKAGKTPI-VVANC 505
Query: 621 DGFVLNRIQYAILDE 665
GF++NRI + L+E
Sbjct: 506 AGFLVNRILISFLNE 520
>UniRef50_A0W3T3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Geobacter lovleyi SZ|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor - Geobacter
lovleyi SZ
Length = 285
Score = 60.1 bits (139), Expect = 5e-08
Identities = 46/199 (23%), Positives = 84/199 (42%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
IG+ G+G +G A L A G++V +Y A + DA I+ L L GL+ GE
Sbjct: 8 IGVAGAGSMGAGIAQLAAMAGFRVRLYARHASALADAAGRIETSLAKLHEKGLI-GE--E 64
Query: 255 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 434
+ + A+ V E + E + K ++ L +V+ I
Sbjct: 65 PTVIRARISNCHEPVALSDCDLVIEAIAEQMAAKCELLAELGAVLGKEAILASSTSSLSI 124
Query: 435 XXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTR 614
+ I H +NP + LVE++ T P R+++ +G+Q V ++
Sbjct: 125 TALGAASGIPQRFIGMHFMNPVPLMELVELIAGSETSPRTIDIARQMVTALGKQSV-CSK 183
Query: 615 EIDGFVLNRIQYAILDEVW 671
+ GF++ R+ +++E +
Sbjct: 184 DQPGFIITRLLCVLINEAF 202
>UniRef50_Q7RZ80 Cluster: Putative uncharacterized protein
NCU04393.1; n=2; Sordariales|Rep: Putative
uncharacterized protein NCU04393.1 - Neurospora crassa
Length = 420
Score = 60.1 bits (139), Expect = 5e-08
Identities = 56/207 (27%), Positives = 90/207 (43%), Gaps = 19/207 (9%)
Frame = +3
Query: 81 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDI-----KYQLHTLENDGL---- 233
I+G+G IGR A+++AS VTVYD+ + + E I KY L + G
Sbjct: 97 IMGAGHIGRRVALVWASALRPVTVYDISKNALRSSTEYITDNLAKYCLEHGTHPGPVHFT 156
Query: 234 --LRGELKASEQ------FQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVV 389
LR A ++ F + +T KG V EC+PENL LK ++ ++
Sbjct: 157 SDLREATTAGKRHGLKLDFSAAHDTEPKSTRKKGPWMVIECLPENLSLKIAALAEIERLL 216
Query: 390 DDNTIXXXXXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTR 569
+N I L+H ++I +H PP V +VE++ + T +
Sbjct: 217 PENCIIASNSSSLMTSEMAPHLQHPGRLINTHYYIPPRNV-MVEVMSSSHTYEGIFPFLT 275
Query: 570 EIMEEIGQQPVSLTREI--DGFVLNRI 644
M+ +G P+ + + GF+ NRI
Sbjct: 276 REMKNMGLTPMVVPPGVQSQGFIFNRI 302
>UniRef50_A3ZYI9 Cluster: Fatty oxidation complex, alpha subunit
FadB; n=1; Blastopirellula marina DSM 3645|Rep: Fatty
oxidation complex, alpha subunit FadB - Blastopirellula
marina DSM 3645
Length = 724
Score = 59.7 bits (138), Expect = 7e-08
Identities = 43/207 (20%), Positives = 86/207 (41%)
Frame = +3
Query: 57 KFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLL 236
K K E + ++G+G++G A G T+ D A+ + + + + + D
Sbjct: 314 KTKIESVSVIGAGIMGAGIAAASIRRGILTTLSDANAEALRRGVAGVLEEA-AYDRDAGK 372
Query: 237 RGELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXX 416
+ KA E + S + V + V E + ENL++K+K++ L+ + D+ I
Sbjct: 373 KTIAKAVEGAAMLNASIS-DSEVAASKLVIEAIVENLEVKRKIYARLEPQLADDAILASN 431
Query: 417 XXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQ 596
L + + H NP + LVE++ T + +G+
Sbjct: 432 TSTLPITQLAANLAKPERFVGIHFFNPVRKMKLVEVIRGAQTSDATVASAVAFAKRLGKF 491
Query: 597 PVSLTREIDGFVLNRIQYAILDEVWRL 677
P+ + + GF++NR+ + ++E L
Sbjct: 492 PI-VVNDGPGFLVNRLLFPYMNEALAL 517
>UniRef50_Q5LVD0 Cluster: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase;
n=6; Rhodobacterales|Rep: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase -
Silicibacter pomeroyi
Length = 698
Score = 59.3 bits (137), Expect = 1e-07
Identities = 51/193 (26%), Positives = 84/193 (43%), Gaps = 3/193 (1%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
IG++G G +G A G VT+ ++ +A E K ++ + L RG+L A
Sbjct: 292 IGVIGGGTMGAGIATAALLSGLSVTMLEMTP----EAAEAAKGRIEGNLSGALKRGKLTA 347
Query: 255 SEQFQCIKGSTDLAT---AVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 425
+ + LA A+ A V E V E++++KK+VF LD+V +
Sbjct: 348 QQFDNLTTKALTLAIDYDALADADLVIEAVFEDMEVKKQVFTKLDAVCKPGAVLASNTSY 407
Query: 426 XXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVS 605
V+ H +P + + L+E+V A T P+VA + + +G+ V
Sbjct: 408 LDINQIAAVTSRPQDVLGLHFFSPAHVMKLLEVVIADQTAPDVAATGFALGKRLGKVSVR 467
Query: 606 LTREIDGFVLNRI 644
DGF+ NRI
Sbjct: 468 -AGVCDGFIGNRI 479
>UniRef50_Q39D25 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=48;
Burkholderiales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 849
Score = 59.3 bits (137), Expect = 1e-07
Identities = 43/199 (21%), Positives = 82/199 (41%), Gaps = 2/199 (1%)
Frame = +3
Query: 54 SKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGL 233
S F K+ ++G+G++G A + V ++D+ AK+ +K +
Sbjct: 40 SNFLIRKVAVLGAGVMGAQIAAHLINARVPVLLFDLPAKEGPKNAIALKAIESLKKLSPA 99
Query: 234 LRGELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXX 413
G ++ + D+A + V + E + E +D K +++ + + N I
Sbjct: 100 PFGVKDDAKYLEAANYEDDIAKLAECDVVI-EAIAERMDWKHDLYKKVAPHIAPNAIFAT 158
Query: 414 XXXXXXXXXXXEGLKH--KSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEI 587
EG KS+ H NPP Y+ LVE++P T+PE+ + + I
Sbjct: 159 NTSGLSITKLSEGFSDELKSRFCGVHFFNPPRYMHLVELIPTAHTRPEILDQLETFLTSI 218
Query: 588 GQQPVSLTREIDGFVLNRI 644
+ V ++ F+ NR+
Sbjct: 219 VGKGVVRAKDTPNFIANRV 237
>UniRef50_A0VLT7 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Dinoroseobacter shibae DFL 12|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Dinoroseobacter shibae DFL 12
Length = 391
Score = 58.4 bits (135), Expect = 2e-07
Identities = 48/149 (32%), Positives = 69/149 (46%), Gaps = 3/149 (2%)
Frame = +3
Query: 81 IVGSGLIGRSWAMLFASVGYQVTVYDV---VAKQITDAIEDIKYQLHTLENDGLLRGELK 251
I+GSG IG WA F G+ V V+D ++T IE + L L D L +
Sbjct: 7 IIGSGRIGSGWAARFLLFGWHVRVFDADPGAQARLTQVIEAARTSLLGLY-DTPLPPPGR 65
Query: 252 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 431
S+ GS +A AV GAV+VQE VPE+L LK++V + + + I
Sbjct: 66 LSQH-----GS--IAEAVAGAVWVQESVPEDLSLKREVVREVQA-HGPEAIVASAASDIP 117
Query: 432 XXXXXEGLKHKSQVIVSHPVNPPYYVPLV 518
EG +V+++ V P Y +P V
Sbjct: 118 LEALREGAARPERVVIARAVAPVYLLPPV 146
>UniRef50_A7S4Z9 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 310
Score = 58.4 bits (135), Expect = 2e-07
Identities = 44/170 (25%), Positives = 76/170 (44%), Gaps = 1/170 (0%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
+ ++G+GL+G A A G +V +YD A+ A+E K L + + L R E+ A
Sbjct: 8 VAVIGAGLMGTCIAGELAYHGARVNLYDRSAQ----AMEKSKEML-IQQKEQLKREEVMA 62
Query: 255 SEQF-QCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 431
+ F + L AV + + E ENL++KK VF+++ N +
Sbjct: 63 TSDFIGTVAFCESLEEAVVNSGLIFEATIENLEVKKSVFKSISQFCRTNAVIATNTLALD 122
Query: 432 XXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIME 581
E + + + + + P Y +P VEI T PE +K ++ +E
Sbjct: 123 TSVVAEHVTNPERCLGIRFLYPVYSIPEVEITLGSQTSPETIQKVQQFLE 172
>UniRef50_Q8YB80 Cluster: 3-HYDROXYBUTYRYL-COA DEHYDROGENASE; n=32;
Proteobacteria|Rep: 3-HYDROXYBUTYRYL-COA DEHYDROGENASE -
Brucella melitensis
Length = 565
Score = 58.0 bits (134), Expect = 2e-07
Identities = 43/190 (22%), Positives = 77/190 (40%), Gaps = 2/190 (1%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGE--L 248
I IVG+G++G A + A G ++D +++ + L L G + E
Sbjct: 48 IAIVGAGVMGTGIAQIAAQAGLVTQIFDAREGAAAASLDRLASTLAKLAEKGKISAEDAQ 107
Query: 249 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 428
A + + +LA V E + E LD K+ +F L++VV N I
Sbjct: 108 TAVSRIEICSSIQELADCD----LVVEAIVEKLDAKQALFLELEAVVSGNCILATNTSSL 163
Query: 429 XXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
+H +V H NP + +VE++ T P V + + +G +
Sbjct: 164 SVTSIARVCRHPERVAGFHFFNPVPLMKVVEVIDGLTTDPAVGDALLVLAKRMGHHGIR- 222
Query: 609 TREIDGFVLN 638
+++ GF++N
Sbjct: 223 AKDMPGFIIN 232
>UniRef50_Q8FRT3 Cluster: Putative 3-hydroxybutyryl-CoA
dehydrogenase; n=2; Corynebacterineae|Rep: Putative
3-hydroxybutyryl-CoA dehydrogenase - Corynebacterium
efficiens
Length = 294
Score = 57.6 bits (133), Expect = 3e-07
Identities = 56/202 (27%), Positives = 84/202 (41%), Gaps = 1/202 (0%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
+G++G G +G A F + G VTV D+ + A E I + + RG
Sbjct: 23 VGVLGGGRMGAGIAHSFLAAGAHVTVVDINDAAVEAARERITNDI----EGSIKRGAEGT 78
Query: 255 SEQF-QCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 431
EQ+ + STD A V V E VPE +DLK F+ + + I
Sbjct: 79 VEQWLDRLTLSTDTAAFADHPVVV-EAVPEIIDLKADSFRKIAAAAPGAVIATNTSSLSV 137
Query: 432 XXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLT 611
L + VI H NP LVE+V A T + RE + +G+ P+ +
Sbjct: 138 SDL---ALSVDNPVIGLHYFNPVPASKLVEVVVADSTPEALVDLAREWVAGLGKTPI-VV 193
Query: 612 REIDGFVLNRIQYAILDEVWRL 677
++ GF +R+ AI E R+
Sbjct: 194 KDAPGFASSRLGVAIALEAIRM 215
>UniRef50_Q1D1F2 Cluster: Fatty oxidation complex, alpha subunit
FadJ; n=2; Cystobacterineae|Rep: Fatty oxidation
complex, alpha subunit FadJ - Myxococcus xanthus (strain
DK 1622)
Length = 746
Score = 57.6 bits (133), Expect = 3e-07
Identities = 51/201 (25%), Positives = 90/201 (44%), Gaps = 2/201 (0%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASV-GYQVTVYDVVAKQITDAIEDIKYQL-HTLENDGLLRG 242
+K+ ++G GL+G A + + + G V V D + A++ ++ L ++ L R
Sbjct: 350 KKVAVLGGGLMGGGIAYVTSVLQGVPVRVKDKDDAGVGRAMKQVQSILDERVKRRSLTRR 409
Query: 243 ELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXX 422
E A + TD + K A V E V E+L LK ++ +++V D TI
Sbjct: 410 EATAKSAL--VTAGTDYS-GFKSADLVIEAVFEDLKLKHRIIAEVEAVTGDQTIFASNTS 466
Query: 423 XXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPV 602
+G + +QVI H +P + +PL+EI+ T V E+ + G + V
Sbjct: 467 SIPITELAKGSRRPAQVIGMHYFSPVHKMPLLEIITHAGTADWVTATCVEVGRKQG-KTV 525
Query: 603 SLTREIDGFVLNRIQYAILDE 665
+ + GF +RI ++E
Sbjct: 526 IVVNDGPGFYTSRILAPYMNE 546
>UniRef50_Q0SEV8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=34;
Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Rhodococcus sp. (strain RHA1)
Length = 298
Score = 57.6 bits (133), Expect = 3e-07
Identities = 48/198 (24%), Positives = 89/198 (44%), Gaps = 4/198 (2%)
Frame = +3
Query: 63 KSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRG 242
K +++G++G+G++G A + A V V++ + I L +L+ G+ G
Sbjct: 5 KIQRVGVIGAGIMGAGIAEVCARAHVDVLVFEQTRELAAAGRSRI---LRSLDR-GVSSG 60
Query: 243 ELKASEQFQC---IKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDD-NTIXX 410
++ E+ Q ++ ++DL + V E V E+ +K ++F LD VV D N +
Sbjct: 61 KITEREREQAAWRLRFTSDLGDFADRQLVV-EAVVEDEKVKSEIFTELDQVVTDPNAVLA 119
Query: 411 XXXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIG 590
K +VI H NP +PLVE+V T V+++ ++
Sbjct: 120 SNTSSIPIMKLGIATKSPERVIGMHFFNPVPVLPLVELVTTLKTSKSVSERAEAFASDVL 179
Query: 591 QQPVSLTREIDGFVLNRI 644
+ V + + GFV+N +
Sbjct: 180 GKQVVRSADRSGFVVNAL 197
>UniRef50_A3JQP6 Cluster: Acetoacetyl-CoA reductase; n=2;
Alphaproteobacteria|Rep: Acetoacetyl-CoA reductase -
Rhodobacterales bacterium HTCC2150
Length = 780
Score = 57.2 bits (132), Expect = 4e-07
Identities = 43/195 (22%), Positives = 87/195 (44%), Gaps = 3/195 (1%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAI-EDIKYQLHTLENDGLLRGE 245
++I ++G+G +G A A+ G++V + D+ K + + E+ +L + L+ +
Sbjct: 7 KRIAVIGAGTMGSGIAGQIANAGHEVLLLDLPGKNSRNEVTENAVTRLLKSDPPALMHKK 66
Query: 246 LKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 425
A + I+ D ++ E + E LD+KK ++Q L+ V+ +
Sbjct: 67 RAALIKVGNIEDDFDKLAECD---WIVEAIVERLDIKKALYQRLNDVISPECVVTSNTST 123
Query: 426 XXXXXXXEGLKH--KSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQP 599
E + +++ ++H NP Y+ L+E+V T P V + +EI +
Sbjct: 124 IPIKLLVEDMPQDFRARFAITHYFNPVRYMRLLELVRGADTNPAVMDRLARYNDEILGKG 183
Query: 600 VSLTREIDGFVLNRI 644
V + GF+ NR+
Sbjct: 184 VVQCGDTPGFLGNRV 198
>UniRef50_A0ISW5 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Serratia proteamaculans 568|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding - Serratia
proteamaculans 568
Length = 509
Score = 57.2 bits (132), Expect = 4e-07
Identities = 42/201 (20%), Positives = 89/201 (44%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
+ ++G+G +GR A L A G + +Y+ + A + I L + G + + K
Sbjct: 11 VAVIGAGTMGRGIAYLLAQNGIRTLLYNRSGNNLNQARDYIIRDLDKKIDGGKISPQKKG 70
Query: 255 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 434
+ + + A+ + V E + E+ K ++ + + V I
Sbjct: 71 EILANLV--FSPIFEAIADSDLVIETIAEHEATKHEILAAIAATVKKEAIIATNTSSLSL 128
Query: 435 XXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTR 614
G+++ ++ I H NP + L+EI+P+ +T + + ++++ IG+Q V + +
Sbjct: 129 NKLAAGVENNARFIGLHFFNPAPLMKLIEIIPSYFTSRATSLRCQQLVTAIGKQFV-VCK 187
Query: 615 EIDGFVLNRIQYAILDEVWRL 677
GF++NR+ E +RL
Sbjct: 188 ATPGFIVNRMARPFYLEGFRL 208
>UniRef50_A0HAN1 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Comamonas testosteroni KF-1
Length = 706
Score = 57.2 bits (132), Expect = 4e-07
Identities = 51/191 (26%), Positives = 82/191 (42%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 251
++GI+G+G +G AM FA+ G V + + + + I+ + G L E
Sbjct: 307 RVGILGAGTMGGGIAMAFANAGIPVVLCEREQAALDRGMAMIERNYQISVSRGGLTAE-A 365
Query: 252 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 431
E+ Q I+ + DL +A V E V E++ +K+ VF LD + TI
Sbjct: 366 VKERMQHIQQTLDL-SAFAEVDLVIEAVFEDMAIKRDVFVQLDRICRKGTILATNTSRLN 424
Query: 432 XXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLT 611
+ VI H +P + L+E+V T V ++ IG+ PV L
Sbjct: 425 INEIAAVTQRPEDVIGLHFFSPANVMKLLEVVRGERTCDAVIASCMQMAVAIGKIPV-LV 483
Query: 612 REIDGFVLNRI 644
+GFV NR+
Sbjct: 484 GVCEGFVGNRM 494
>UniRef50_Q5V581 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Haloarcula marismortui|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Haloarcula marismortui (Halobacterium
marismortui)
Length = 290
Score = 57.2 bits (132), Expect = 4e-07
Identities = 45/201 (22%), Positives = 87/201 (43%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
+ ++G+G GR A G++V + A + D +++I+ + +L A
Sbjct: 3 VAVLGTGQRGRDVAQRCVRAGHEVRLQGTDASDVMDRVDEIRRAFNR---------DLSA 53
Query: 255 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 434
I G+T L +AV G+ V + + ++V +++V+D TI
Sbjct: 54 G-----IDGTTGLESAVSGSDVVIDATNGGTESHREVVAETETMVEDETIIAVSDTSLSV 108
Query: 435 XXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTR 614
GL+ + + + V+PP +VE+V A T + + +E + PV + R
Sbjct: 109 TAVATGLRSPDRAVGLNLVDPPDGA-IVEVVIAEQTTAATRDRVTDFVESLDASPV-VVR 166
Query: 615 EIDGFVLNRIQYAILDEVWRL 677
+ GF R++ A + E R+
Sbjct: 167 DTPGFAALRLELAAIAEAIRM 187
>UniRef50_A7INS1 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=5; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase NAD-binding -
Xanthobacter sp. (strain Py2)
Length = 789
Score = 56.8 bits (131), Expect = 5e-07
Identities = 43/198 (21%), Positives = 86/198 (43%), Gaps = 3/198 (1%)
Frame = +3
Query: 60 FKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLR 239
F +K+ ++G+G++G A A+ G +V + D+V + + + + L
Sbjct: 16 FDIKKVAVIGAGVMGAGIAAHVANAGIEVLLLDIVPEGAANRNAIAEKAVEKLLKADPAA 75
Query: 240 GELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXX 419
K + + D + + ++ E V E LD+K+ ++ +++ +
Sbjct: 76 FMSKRAAKLVTAGNIEDNLSDLASCDWIVEAVIERLDIKQALYAKIEAARRPGSAVSSNT 135
Query: 420 XXXXXXXXXEGLKH--KSQVIVSHPVNPPYYVPLVEIVPAPWTKP-EVAKKTREIMEEIG 590
GL + +++H NPP Y+ L+EIV P T P VA R ++G
Sbjct: 136 STIPLGDLTAGLPESFRRDFLITHFFNPPRYMRLLEIVAGPETNPATVAAVARFADVKLG 195
Query: 591 QQPVSLTREIDGFVLNRI 644
+ V+ ++ GF+ NR+
Sbjct: 196 KTVVT-CKDTPGFIANRL 212
>UniRef50_A5IPA0 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=14; Staphylococcus|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Staphylococcus aureus subsp. aureus JH9
Length = 753
Score = 56.8 bits (131), Expect = 5e-07
Identities = 45/202 (22%), Positives = 83/202 (41%), Gaps = 3/202 (1%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVA-KQITDAIEDIKYQLHTLENDGLLRGEL 248
K+ ++G+G +G A LF + G +V + D+V K + I Y T + LL +L
Sbjct: 5 KVTVLGAGTMGAQLAALFVNAGLKVKLLDIVVDKNDPNLIAKKSYDKITDKKRPLLF-DL 63
Query: 249 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 428
DL A E V E++++K V+Q + ++ +
Sbjct: 64 NLVSHLTYGNFDDDLVN--DDADLYIEAVKEDIEIKHAVWQQVLQHAKEDALFATNTSGI 121
Query: 429 XXXXXXEGLKHKSQ--VIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPV 602
+ K Q H NPP + LVE++P TK + + + + + V
Sbjct: 122 PINAIAQAFNEKDQERFFGLHFFNPPRIMKLVELIPTSHTKESIILDVKNFAQNVLGKGV 181
Query: 603 SLTREIDGFVLNRIQYAILDEV 668
+ ++ GFV NR+ ++++
Sbjct: 182 IVVNDVPGFVANRVGTQTMNDI 203
>UniRef50_Q8FX64 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=10; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase family protein - Brucella suis
Length = 509
Score = 56.0 bits (129), Expect = 9e-07
Identities = 43/190 (22%), Positives = 76/190 (40%), Gaps = 2/190 (1%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGE--L 248
I IVG+G++G A + A G ++D + + + L L G + E
Sbjct: 8 IAIVGAGVMGTGIAQIAAQAGLVTQIFDAREGAAAASRDRLASTLAKLAEKGKISAEDAQ 67
Query: 249 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 428
A + + +LA V E + E LD K+ +F L++VV N I
Sbjct: 68 TAVSRIEICSSIQELADCD----LVVEAIVEKLDAKQALFLELEAVVSGNCILATNTSSL 123
Query: 429 XXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
+H +V H NP + +VE++ T P V + + +G +
Sbjct: 124 SVTSIARVCRHPERVAGFHFFNPVPLMKVVEVIDGLTTDPAVGDALLVLAKRMGHHGIR- 182
Query: 609 TREIDGFVLN 638
+++ GF++N
Sbjct: 183 AKDMPGFIIN 192
>UniRef50_A6GC68 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Plesiocystis pacifica SIR-1|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Plesiocystis pacifica SIR-1
Length = 733
Score = 56.0 bits (129), Expect = 9e-07
Identities = 46/186 (24%), Positives = 79/186 (42%), Gaps = 8/186 (4%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHT----LENDG-- 230
E++ I+G+G++G A + A GYQV + D+ + + + + QL L++ G
Sbjct: 333 ERVAILGAGMMGAGLAYICADAGYQVVLKDINQEALDKGVAHFEAQLRKRKRHLDDAGRQ 392
Query: 231 LLRGELKASEQFQCIK--GSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 404
+R L S + + G TDL + E V ENLDLK +V + + + + I
Sbjct: 393 AIRDRLTPSLELSALSDNGGTDL---------IIEAVFENLDLKHRVTRETEPTLSADGI 443
Query: 405 XXXXXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEE 584
+ H + I H +P +PL+EIV P T + +
Sbjct: 444 WASNTSAIPIGDLAKVSAHADRFIGLHYFSPVEVMPLLEIVVGPETSERTLARCLDFCRR 503
Query: 585 IGQQPV 602
I + P+
Sbjct: 504 IKKLPI 509
>UniRef50_A5WEP3 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=7; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Psychrobacter sp. PRwf-1
Length = 723
Score = 56.0 bits (129), Expect = 9e-07
Identities = 46/197 (23%), Positives = 85/197 (43%), Gaps = 3/197 (1%)
Frame = +3
Query: 63 KSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRG 242
K K+GI+G+G++G A + A G V + D +A E K L + + RG
Sbjct: 321 KVSKVGILGAGMMGAGIAYVSAKAGIDVVLLDTSI----EAAEKGKDYSSKLLDKAIARG 376
Query: 243 ELKASEQFQCIKGSTDLATA---VKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXX 413
++ Q + + TA ++ + E V E++D+K +N ++V+ + I
Sbjct: 377 R-STEQKKQALLDKINTTTAYDDLEDCDLIIEAVFEDIDIKAACTRNTEAVIAETAIYAS 435
Query: 414 XXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQ 593
+ K +Q I H +P +PLVEI+ T K + + +I +
Sbjct: 436 NTSTLPITELAKASKRPNQFIGLHFFSPVDKMPLVEIIVGEETDDATLAKGFDYVGQIAK 495
Query: 594 QPVSLTREIDGFVLNRI 644
P+ + + GF +R+
Sbjct: 496 TPI-VVNDSRGFYTSRV 511
>UniRef50_A1BCA2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Paracoccus denitrificans PD1222|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Paracoccus denitrificans (strain Pd 1222)
Length = 371
Score = 56.0 bits (129), Expect = 9e-07
Identities = 45/190 (23%), Positives = 79/190 (41%), Gaps = 1/190 (0%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDG-LLRGELK 251
I ++G G +G A +A+ G+ V D V + A+ ++ L G L + +L
Sbjct: 4 IAVIGLGTMGLGIAQTYAAAGFAVLATDAVPEARETALGRLRAGLAPRVRAGKLAQADLD 63
Query: 252 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 431
A + A A+ E V E + +K+ +F L++VV + +
Sbjct: 64 AILARITVVDGPKAMGATDLAI---EAVVERMPVKQSLFAALEAVVAPDAVLASNTSSLS 120
Query: 432 XXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLT 611
EGL +++ H NP + LVE+V P T + R + E G+ +
Sbjct: 121 MAAMAEGLARPERLLGLHFFNPAPVMKLVELVAHPGTGAAALDRARRLTEAAGKTVIPCP 180
Query: 612 REIDGFVLNR 641
+ GF++NR
Sbjct: 181 -DRPGFIVNR 189
>UniRef50_A0Z5J4 Cluster: Enoyl-CoA hydratase; n=2; unclassified
Gammaproteobacteria (miscellaneous)|Rep: Enoyl-CoA
hydratase - marine gamma proteobacterium HTCC2080
Length = 699
Score = 56.0 bits (129), Expect = 9e-07
Identities = 45/192 (23%), Positives = 80/192 (41%), Gaps = 2/192 (1%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
+GI+G+G +G AM FA G VT+ D+ + + +E I + +G L
Sbjct: 296 VGIIGAGTMGGGIAMCFAQAGIAVTLVDMTDEAVKGGLEKIAKNYAI----SVKKGRLTV 351
Query: 255 SEQFQCIKGSTDLAT--AVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 428
++ + T ++ + V E V ENL++KK+VF LD + +
Sbjct: 352 AQTDAILANITTSSSFDDLANVDMVIEAVFENLEVKKEVFGKLDVICKPGAVLASNTSYQ 411
Query: 429 XXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
V+ H +P + L+E+V + V + ++IG+ V L
Sbjct: 412 SIDAIAAATSRPESVLGMHFFSPANVMKLLEVVKGASSSDIVIATAMAVGKKIGKVSV-L 470
Query: 609 TREIDGFVLNRI 644
+ GF+ NR+
Sbjct: 471 SGMCYGFIGNRM 482
>UniRef50_Q668V1 Cluster: Fatty acid oxidation complex subunit alpha
[Includes: Enoyl-CoA hydratase/3-hydroxybutyryl-CoA
epimerase (EC 4.2.1.17) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)]; n=95; Proteobacteria|Rep:
Fatty acid oxidation complex subunit alpha [Includes:
Enoyl-CoA hydratase/3-hydroxybutyryl-CoA epimerase (EC
4.2.1.17) (EC 5.1.2.3); 3-hydroxyacyl-CoA dehydrogenase
(EC 1.1.1.35)] - Yersinia pseudotuberculosis
Length = 753
Score = 56.0 bits (129), Expect = 9e-07
Identities = 50/202 (24%), Positives = 88/202 (43%), Gaps = 1/202 (0%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFAS-VGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
++G++G GL+G A + A+ G V + D+ + I A++ L +R
Sbjct: 317 RVGVLGGGLMGGGIANVTATRAGLPVRIKDINPQGINQALKYTWDALGKRVRSKRMR-PT 375
Query: 249 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 428
+ Q I GSTD + + V E V E+L LK+++ +++ +TI
Sbjct: 376 EQQRQMMLISGSTDYRGFERVDIVV-EAVFEDLSLKQQMVADIERFGAAHTIFASNTSSL 434
Query: 429 XXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
+ QVI H +P +PLVE++P T E T + + G+ + +
Sbjct: 435 PISQIAALAQRPEQVIGLHYFSPVDKMPLVEVIPHEKTSEETIATTVALARKQGKTAI-V 493
Query: 609 TREIDGFVLNRIQYAILDEVWR 674
+ GF +NRI ++E R
Sbjct: 494 VADRAGFYVNRILAPYINEAAR 515
>UniRef50_Q1GGC1 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=4; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase NAD-binding -
Silicibacter sp. (strain TM1040)
Length = 733
Score = 55.6 bits (128), Expect = 1e-06
Identities = 48/206 (23%), Positives = 91/206 (44%), Gaps = 3/206 (1%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
+KIG++G+G++G A++ A G +V + D + DA + K T + G+ RG+
Sbjct: 327 KKIGVLGAGMMGAGIALVSAQAGMEVVLID----RDQDAADKGKAYSATYMDKGIKRGKA 382
Query: 249 ---KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXX 419
K I + DL A+KG + E V E+ +K ++ + +++++ ++ I
Sbjct: 383 TPEKKEALLAQITATADL-DALKGCDLIIEAVFEDPGVKAEMTKKVEAIIPEDCIFASNT 441
Query: 420 XXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQP 599
E Q I H +P + LVEI+ T K + + +I + P
Sbjct: 442 STLPITSLAEASVRPEQFIGIHFFSPVEKMFLVEIIKGEKTGDRAVAKALDYVRQIRKTP 501
Query: 600 VSLTREIDGFVLNRIQYAILDEVWRL 677
+ + + F NR ++E R+
Sbjct: 502 I-VVNDARFFYCNRCIIPYINEGARM 526
>UniRef50_A0J682 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Shewanella woodyi ATCC 51908|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Shewanella woodyi ATCC 51908
Length = 696
Score = 55.6 bits (128), Expect = 1e-06
Identities = 44/190 (23%), Positives = 83/190 (43%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
+G+VG+G +G A F G + + + + +++++ + G + E
Sbjct: 308 VGVVGAGNMGVGIARCFIDAGMDLIWIEQTEEALLRGMDNLRKGYQSKITKGHMT-EQDL 366
Query: 255 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 434
++ Q +KGST + + V E E+L++KK +F+ LD D+ I
Sbjct: 367 DDKMQLVKGST-VYDRLAPCDLVVEAAFEDLEVKKIIFKALDQHCKDSAILATNTSYLDI 425
Query: 435 XXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTR 614
+ QV+ H +P + + L+EIV A T +V K + ++ + PV +
Sbjct: 426 NSIAKVTSRPDQVVGLHFFSPAHVMKLIEIVRAENTADDVIKTMLALGVKLRKYPVEV-G 484
Query: 615 EIDGFVLNRI 644
GF NR+
Sbjct: 485 VCFGFAANRM 494
>UniRef50_Q47DJ5 Cluster: Enoyl-CoA
hydratase/isomerase:3-hydroxyacyl-CoA dehydrogenase, C-
terminal:3-hydroxyacyl-CoA dehydrogenase, NAD-binding;
n=1; Dechloromonas aromatica RCB|Rep: Enoyl-CoA
hydratase/isomerase:3-hydroxyacyl-CoA dehydrogenase, C-
terminal:3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Dechloromonas aromatica (strain RCB)
Length = 705
Score = 55.2 bits (127), Expect = 2e-06
Identities = 42/188 (22%), Positives = 76/188 (40%)
Frame = +3
Query: 81 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKASE 260
++G+G++G A A G V + D+ +Q+ + + K Q+ G + E K +
Sbjct: 309 VLGAGIMGGGIAFTSALKGVPVRLKDISRQQLDLGMAEAKKQIGRQIKSGRV-SEAKGQQ 367
Query: 261 QFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXX 440
I+ D A V E + ENL +K V L+ V +T+
Sbjct: 368 VLTSIQPQLDYA-GFSDCDLVVEAIIENLKVKHAVLSELEQAVAPDTVIASNTSSLRIDE 426
Query: 441 XXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREI 620
L+ + H NP + LVE++ T + +G+ P+ + ++
Sbjct: 427 IAMPLQRPENFVGMHFFNPVPVMALVEVIKGSRTSDVAVSTAVDYAVTMGKTPI-VVQDC 485
Query: 621 DGFVLNRI 644
GF++NRI
Sbjct: 486 PGFLVNRI 493
>UniRef50_A6GBG1 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerase family protein; n=1; Plesiocystis
pacifica SIR-1|Rep: 3-hydroxyacyl-CoA
dehydrogenase/enoyl-CoA hydratase/isomerase family
protein - Plesiocystis pacifica SIR-1
Length = 789
Score = 55.2 bits (127), Expect = 2e-06
Identities = 32/121 (26%), Positives = 58/121 (47%), Gaps = 2/121 (1%)
Frame = +3
Query: 288 DLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXXEGLKH-- 461
DL AV + V E + E LD+K+ VF+ + + + TI E L
Sbjct: 71 DLERAVAESDIVIEAIIERLDIKQTVFKKVAAAAKETTILASNTSGIPIADIAEALDEGA 130
Query: 462 KSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNR 641
+ + + H NPP ++ L+E++P+ +T + + + +E+ + V L R+ F+ NR
Sbjct: 131 RERFLGLHFFNPPRWMHLLEVIPSKYTAKKYVDEVAKFSDEVLGKGVVLCRDTPNFIGNR 190
Query: 642 I 644
I
Sbjct: 191 I 191
>UniRef50_A4WWF6 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=5; Rhodobacteraceae|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Rhodobacter sphaeroides ATCC 17025
Length = 673
Score = 55.2 bits (127), Expect = 2e-06
Identities = 44/191 (23%), Positives = 80/191 (41%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 251
+IG++G G +G A A+ G + T+ + + I+ ++ G L
Sbjct: 292 RIGVIGGGTMGSGIAAAIAAAGLEATLAETGPDALEAGIKRVRAIFEAQVTRG-LTDRAG 350
Query: 252 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 431
A+++ + G+ L + V E V E+L +K++VF++L + + I
Sbjct: 351 AADRLARVSGTVGLG-PLADCDLVIEAVFEDLAVKRRVFEDLTRLCRPDAILATNTSYLD 409
Query: 432 XXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLT 611
GL + + I H +P + L+EIVP T + +G+ PV
Sbjct: 410 PERIVAGLPNPDRFIALHFFSPAQVMKLLEIVPLVATTSRTLATGFALAARLGKIPVQAG 469
Query: 612 REIDGFVLNRI 644
+GF+ NRI
Sbjct: 470 NG-EGFIGNRI 479
>UniRef50_Q67L77 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Symbiobacterium thermophilum|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Symbiobacterium thermophilum
Length = 296
Score = 54.8 bits (126), Expect = 2e-06
Identities = 47/197 (23%), Positives = 81/197 (41%), Gaps = 1/197 (0%)
Frame = +3
Query: 78 GIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQL-HTLENDGLLRGELKA 254
GIVG+G GR A L A+ G +V + +++ A + L H +E L + E +A
Sbjct: 7 GIVGTGPSGRGIAQLVATQGLEVIMVGRSEEELEQARRQLDLALQHEIEKWALTQSEKRA 66
Query: 255 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 434
I +TD+ K + V E + K++F+ LD V I
Sbjct: 67 I--LARISMTTDINELAKADFVIATLVVEIAE-DKEIFRTLDQVCRREVILASNTSTLSI 123
Query: 435 XXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTR 614
+VI H + P +V++V T E + +ME +G+ V +
Sbjct: 124 TEMASATNRPDKVIGCHFLQPIPRTRVVQVVRGLKTSDETVSQVMALMERLGRTGVEVF- 182
Query: 615 EIDGFVLNRIQYAILDE 665
E G++ R+ +++E
Sbjct: 183 ESPGYITTRLIVPLINE 199
>UniRef50_Q8ZAN0 Cluster: Fatty acid oxidation complex subunit alpha
[Includes: Enoyl-CoA
hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA
isomerase/3- hydroxybutyryl-CoA epimerase (EC 4.2.1.17)
(EC 5.3.3.8) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)]; n=116; cellular
organisms|Rep: Fatty acid oxidation complex subunit
alpha [Includes: Enoyl-CoA
hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA
isomerase/3- hydroxybutyryl-CoA epimerase (EC 4.2.1.17)
(EC 5.3.3.8) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)] - Yersinia pestis
Length = 729
Score = 54.8 bits (126), Expect = 2e-06
Identities = 42/193 (21%), Positives = 81/193 (41%)
Frame = +3
Query: 81 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKASE 260
++G+G++G A A V + D+ + + + L+ G + G LK +
Sbjct: 318 VLGAGIMGGGIAYQSALKSVPVIMKDINENSLDLGMNEAAKLLNKQLERGKVDG-LKMAS 376
Query: 261 QFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXX 440
I+ + D A + V V E V EN +K V +++++ ++T+
Sbjct: 377 ILATIRPTLDYAGIERAQVIV-EAVVENPKVKAAVLAEVEALIGEDTVLASNTSTIPIDQ 435
Query: 441 XXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREI 620
+ LK H NP + +PLVEI+ T + ++G+ P+ + +
Sbjct: 436 LAKSLKRPENFCGMHFFNPVHRMPLVEIIRGAKTSDKTLAAVVAYATQMGKTPI-VVNDC 494
Query: 621 DGFVLNRIQYAIL 659
GF +NR+ + L
Sbjct: 495 PGFFVNRVLFPYL 507
>UniRef50_Q5P607 Cluster: Fusion of 3-hydroxyacyl-CoA dehydrogenase
and enoyl-CoA hydratase; n=2; Proteobacteria|Rep: Fusion
of 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA
hydratase - Azoarcus sp. (strain EbN1) (Aromatoleum
aromaticum (strain EbN1))
Length = 671
Score = 54.4 bits (125), Expect = 3e-06
Identities = 43/195 (22%), Positives = 89/195 (45%), Gaps = 5/195 (2%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASV--GYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
+ ++G+G IG S ++T+ DV + A++ + H + +G++
Sbjct: 21 VAVIGAGTIGPDIGYYLKSALPELKLTLVDVSQAALDRALQ----RFHDYAAKAVAKGKM 76
Query: 249 KASEQFQC---IKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXX 419
+E + G+ D + A +V E EN+ LK+++F ++++VV + +
Sbjct: 77 SEAEARAVTANLAGTLDYGD-IADADWVLEAATENIALKRRIFADVEAVVRPDALITSNT 135
Query: 420 XXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQP 599
L+H + V+H P + P+VE+V +P V + R + G+ P
Sbjct: 136 SSLPAAQIFAELRHPERATVTHFFAPAWRNPVVEVVRWEKAEPAVVEYLRWLFCSTGKVP 195
Query: 600 VSLTREIDGFVLNRI 644
+ +T ++ F+L+RI
Sbjct: 196 L-VTDDVVCFMLDRI 209
>UniRef50_A0LI43 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Syntrophobacter fumaroxidans MPOB|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
Length = 681
Score = 54.4 bits (125), Expect = 3e-06
Identities = 46/197 (23%), Positives = 82/197 (41%), Gaps = 1/197 (0%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFAS-VGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
K+GIVG+GL+ A LF + V + D+ + + + L G L E
Sbjct: 318 KVGIVGAGLMASQLAQLFIERLEVPVVMKDISPEALEKGCGQVVEGFRRLGEKGKLT-EG 376
Query: 249 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 428
KA + G+ D FV E V E + +KK+V L+ ++ + +
Sbjct: 377 KARHLAGLVSGTLDFRD-FSDCDFVIEAVFEEMAVKKQVLGELEPLLRPDAVIATNTSSL 435
Query: 429 XXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
L+ +++ H NP +PLVE++ T E ++ ++ + V L
Sbjct: 436 SVTEMASVLRVPGRMLGFHFFNPVAVLPLVEVIRTAQTSGEALATAFDLARKLRKTGV-L 494
Query: 609 TREIDGFVLNRIQYAIL 659
++ F++NRI +L
Sbjct: 495 VKDAPAFLVNRILVKML 511
>UniRef50_Q0RL76 Cluster: Putative 3-hydroxybutyryl-CoA
dehydrogenase; n=1; Frankia alni ACN14a|Rep: Putative
3-hydroxybutyryl-CoA dehydrogenase - Frankia alni
(strain ACN14a)
Length = 234
Score = 54.0 bits (124), Expect = 4e-06
Identities = 36/130 (27%), Positives = 57/130 (43%), Gaps = 3/130 (2%)
Frame = +3
Query: 297 TAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXXEGLKHKSQVI 476
+AV GA V E VPE+L LK +VF+ LD V + ++V+
Sbjct: 69 SAVAGAAVVIEAVPEDLALKVRVFRELDRVAAAGAVLATNSSGFPVGALAAATDRPTRVL 128
Query: 477 VSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREID---GFVLNRIQ 647
H +P + EIV T P+ + +G+ PV + R+ G+V NR+
Sbjct: 129 GWHWSSPAQIMRFAEIVVTEHTDPDAVATVTRLAHGLGKNPV-VVRDAPMAWGYVANRVY 187
Query: 648 YAILDEVWRL 677
+A + E R+
Sbjct: 188 WAAVAEARRI 197
>UniRef50_A4BL13 Cluster: Fatty oxidation complex, alpha subunit;
n=3; Proteobacteria|Rep: Fatty oxidation complex, alpha
subunit - Nitrococcus mobilis Nb-231
Length = 726
Score = 54.0 bits (124), Expect = 4e-06
Identities = 47/204 (23%), Positives = 91/204 (44%), Gaps = 2/204 (0%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFAS-VGYQVTVYDVVAKQITDAIEDIKYQL-HTLENDGLLRGE 245
++G++G+GL+G + + A+ V + DV K + ++ I ++ L + R E
Sbjct: 331 RVGVLGAGLMGAGISFVTAARAKVPVRLKDVEPKGLASGLKYIDERIDQRLSRHAISRFE 390
Query: 246 LKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 425
+E+ +C T + + V E V E+L+LK ++ + +++ + + I
Sbjct: 391 ---AERARCRVTPTLDFSGCRSLDLVIEAVFEDLELKHRMIREVEANCNADVIFASNTSS 447
Query: 426 XXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVS 605
+ + VI H +P +PL+E++ T PEV G+ P+
Sbjct: 448 LPLARIAQAAERPQNVIGLHYFSPVDRMPLLEVIAHERTAPEVIATAMAFGRAQGKTPI- 506
Query: 606 LTREIDGFVLNRIQYAILDEVWRL 677
+ R+ GF +NRI L+E L
Sbjct: 507 VVRDGVGFYVNRILAPYLNEAVHL 530
>UniRef50_A0LDJ8 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Magnetococcus sp. MC-1|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Magnetococcus sp. (strain MC-1)
Length = 717
Score = 54.0 bits (124), Expect = 4e-06
Identities = 45/201 (22%), Positives = 89/201 (44%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
+ +VG G++GR+ A+ A G QV++ + + + A+++ D L +L
Sbjct: 312 VHVVGDGVMGRAIAVWCALQGMQVSLQGLSTELLGRALQEATQLARKKRLDRLATRDL-L 370
Query: 255 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 434
+G V A V E + E++ K++++ L+ + ++ +
Sbjct: 371 DRLMPDQRGD-----GVCHADLVIEAIFEDVTAKQQLYAALEPRMREHALLATNTSAIPL 425
Query: 435 XXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTR 614
+GLK Q++ H NP +PLVE+V P T + + + I + P+ + +
Sbjct: 426 QTLAQGLKRPQQLLGLHFFNPVARMPLVEVVEGPQTSMQALQMGYRFVHAIQRLPLPV-K 484
Query: 615 EIDGFVLNRIQYAILDEVWRL 677
GF++NR+ L E R+
Sbjct: 485 SRPGFLVNRVLMPYLMEAVRM 505
>UniRef50_O17761 Cluster: Putative uncharacterized protein ech-8;
n=4; Caenorhabditis|Rep: Putative uncharacterized
protein ech-8 - Caenorhabditis elegans
Length = 437
Score = 54.0 bits (124), Expect = 4e-06
Identities = 47/206 (22%), Positives = 88/206 (42%), Gaps = 3/206 (1%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLH-TLENDGLLR-- 239
+ + ++G G +GR A+ F G++ + +V K A E K +L T + + R
Sbjct: 40 KSVAVIGGGTMGRGIAIAFCLSGFETYLVEVNNK----AAEFCKNELEITYKREKAFRRL 95
Query: 240 GELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXX 419
+ K + + ++ +TD + + E V E++ LKK++F LD + + I
Sbjct: 96 NDSKVEKLRKNLQITTDFQK-LNNCDLIVEAVFEDMKLKKELFTKLDKICKPSCIFGTNT 154
Query: 420 XXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQP 599
L+ ++V+ H NP + +VE++ T + E I + P
Sbjct: 155 SSLDLNEMSSVLRDPTKVVGIHFFNPANLIRMVEVIYGSKTSSKAVATAFEACRSIKKLP 214
Query: 600 VSLTREIDGFVLNRIQYAILDEVWRL 677
V L FV NR+ L++ +L
Sbjct: 215 V-LVGNCPAFVFNRLLGVYLNQSQKL 239
>UniRef50_Q5P5K6 Cluster: Fusion of 3-hydroxyacyl-CoA dehydrogenase
and enoyl-CoA hydratase; n=20; Proteobacteria|Rep:
Fusion of 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA
hydratase - Azoarcus sp. (strain EbN1) (Aromatoleum
aromaticum (strain EbN1))
Length = 797
Score = 53.6 bits (123), Expect = 5e-06
Identities = 48/201 (23%), Positives = 86/201 (42%), Gaps = 4/201 (1%)
Frame = +3
Query: 54 SKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQ-ITDAIEDIKYQLHTLENDG 230
SK K+ ++G+G++G A A+ V ++D+ AK + + D T +
Sbjct: 2 SKLIIRKVAVLGAGVMGAQIAAHCANADVPVVLFDLPAKDGPPNRVVDRAIGGLTKLDPA 61
Query: 231 LLRGELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXX 410
L ++AS +DL ++ V E + E L+ K+ ++ + + I
Sbjct: 62 PLAAAVRASH-IDAANYDSDLER-LRDCDLVIEAIAEKLEWKRDLYAKAAPYLRPDAIFA 119
Query: 411 XXXXXXXXXXXXEGLKH--KSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTRE-IME 581
EGL +S+ H NPP Y+ LVE++PAP T P + ++
Sbjct: 120 SNTSGLSIATLAEGLPEALRSRFCGVHFFNPPRYMALVELIPAPATDPLMLDALEAWLVT 179
Query: 582 EIGQQPVSLTREIDGFVLNRI 644
+G+ V ++ FV NR+
Sbjct: 180 RLGKSIVR-AKDTPNFVANRV 199
>UniRef50_A3M4C7 Cluster: PaaC; n=1; Acinetobacter baumannii ATCC
17978|Rep: PaaC - Acinetobacter baumannii (strain ATCC
17978 / NCDC KC 755)
Length = 435
Score = 53.6 bits (123), Expect = 5e-06
Identities = 35/125 (28%), Positives = 56/125 (44%)
Frame = +3
Query: 300 AVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXXEGLKHKSQVIV 479
A++ A V E V E ++K+ +F+ L + TI G+ H +V+
Sbjct: 7 ALRDADLVIEAVVEKKEVKQSLFKQLAEICSAQTIFASNTSSISVTAISAGIAHPERVVG 66
Query: 480 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 659
H NP + LVEIV T + + +M + + PV LT+ GF++NRI
Sbjct: 67 LHFFNPAPVMKLVEIVQGLKTPNSLCLALKNLMLDWKKIPV-LTKSTPGFIVNRIARPFY 125
Query: 660 DEVWR 674
E +R
Sbjct: 126 AEGFR 130
>UniRef50_A1IDF2 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerase family protein precursor; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep:
3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerase family protein precursor -
Candidatus Desulfococcus oleovorans Hxd3
Length = 801
Score = 53.6 bits (123), Expect = 5e-06
Identities = 47/204 (23%), Positives = 84/204 (41%), Gaps = 10/204 (4%)
Frame = +3
Query: 63 KSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIED--------IKYQLHTL 218
K +K ++GSG++G A L AS G + + D+V +TD + +K+ T+
Sbjct: 4 KIKKAAVIGSGVMGGGIAALLASAGVETLLLDIVPFDLTDEQKKDPAARNRIVKFGYDTI 63
Query: 219 ENDGLLRGELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDN 398
+ I D + ++ E V ENL +K+++F+ ++ V
Sbjct: 64 MMSRPAALMHSSDAALISIGNLEDDFDKLADCDWIVEVVVENLKIKQQLFKRIEPVRKKG 123
Query: 399 TIXXXXXXXXXXXXXXEGLKH--KSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTRE 572
+I EGL K + +H NP Y+ L+EI+ T EV +
Sbjct: 124 SIISSNTSGIPLKAMSEGLSSDFKQHFLGTHFFNPVRYMHLLEIIKGEETSEEVLRFMAA 183
Query: 573 IMEEIGQQPVSLTREIDGFVLNRI 644
E+ + + ++ F+ NRI
Sbjct: 184 FGEKRLGKGIVWAKDTPNFIGNRI 207
>UniRef50_A6UH30 Cluster: 3-hydroxybutyryl-CoA epimerase; n=2;
Sinorhizobium|Rep: 3-hydroxybutyryl-CoA epimerase -
Sinorhizobium medicae WSM419
Length = 442
Score = 53.2 bits (122), Expect = 6e-06
Identities = 45/202 (22%), Positives = 86/202 (42%), Gaps = 3/202 (1%)
Frame = +3
Query: 81 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA-- 254
++G G +G A + G + V+ ++ A E +L + + + R + A
Sbjct: 49 VIGGGTMGTGIAAALCNAGLPL----VIVERDEAAREGAVARLRAIFDGAVKRRRISAGL 104
Query: 255 -SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 431
+E+ + G+TD A + + + E V E+LD+K+ VF+ + + + +
Sbjct: 105 AAERLARVTGATDYAVLAEADLII-EAVFEDLDVKRDVFRKVAAACRHDAVLATNTSYLN 163
Query: 432 XXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLT 611
+G+ + + H +P + L+EIVP T PE + + + PV
Sbjct: 164 PERIADGIASPERFLGLHFFSPAQVMKLLEIVPTGATAPEALATGFALARMLNKIPVRAG 223
Query: 612 REIDGFVLNRIQYAILDEVWRL 677
DGF+ NRI + + RL
Sbjct: 224 IS-DGFIGNRILKVMRGQAERL 244
>UniRef50_Q7WIS8 Cluster: Putative enoyl-CoA isomerase; n=2;
Bordetella|Rep: Putative enoyl-CoA isomerase -
Bordetella bronchiseptica (Alcaligenes bronchisepticus)
Length = 694
Score = 52.8 bits (121), Expect = 8e-06
Identities = 44/197 (22%), Positives = 77/197 (39%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
E++ +VG+G +G + A G V +DV A ++ + L L
Sbjct: 288 EQVAVVGAGTMGTGIVICLADAGLPVIWHDVDADRLAQGRAQVCQHFERLAARKRLTS-- 345
Query: 249 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 428
+ +EQ +T + A E V E++ +K VF+ LD V+ I
Sbjct: 346 RQAEQRVAAVATTGEMAGIAQADLAIEAVFEDMAVKCAVFRELDRVLKPGAILGTNTSTL 405
Query: 429 XXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
+ V+ H +P +PL+EIV T +V + + + + V +
Sbjct: 406 DVDRIAHSTRRPQDVVGLHFFSPAPVMPLLEIVRGAATHADVVAAAQGLARRLRKTAV-V 464
Query: 609 TREIDGFVLNRIQYAIL 659
DGF+ NR+ + L
Sbjct: 465 AGVCDGFIGNRMWHQYL 481
>UniRef50_Q6MM12 Cluster: Fatty oxidation complex, alpha subunit;
n=1; Bdellovibrio bacteriovorus|Rep: Fatty oxidation
complex, alpha subunit - Bdellovibrio bacteriovorus
Length = 717
Score = 52.8 bits (121), Expect = 8e-06
Identities = 41/197 (20%), Positives = 82/197 (41%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
+G++G+G +G A + A G QV + D+ + ++ L + + +
Sbjct: 321 LGVLGAGTMGGGIAYVAADKGIQVRMKDLNTDALGKGLKHASDLWMKLVKRKSI-DKYQF 379
Query: 255 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 434
++ + STD A K V E + E++ +K+KV + + I
Sbjct: 380 QQKMDLVSVSTDYA-GFKNLDVVVEAIVEDMGIKQKVIGECAGQMRPDAIIATNTSSLSV 438
Query: 435 XXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTR 614
+G H NP +PL+E++ T E E+ +++G+ PV + +
Sbjct: 439 TEMAKGHPRPEYFAGMHFFNPVNKMPLIEVIRGEKTSDETIATIYELSKKMGKMPV-VVK 497
Query: 615 EIDGFVLNRIQYAILDE 665
+ GF++NR+ + E
Sbjct: 498 DGPGFLVNRLLLPYMGE 514
>UniRef50_Q5NW50 Cluster: DitN-like 3-hydroxyacyl-CoA
dehydrogenase,possibly related to diterpenoid
metabolism; n=6; Proteobacteria|Rep: DitN-like
3-hydroxyacyl-CoA dehydrogenase,possibly related to
diterpenoid metabolism - Azoarcus sp. (strain EbN1)
(Aromatoleum aromaticum (strain EbN1))
Length = 299
Score = 52.8 bits (121), Expect = 8e-06
Identities = 40/195 (20%), Positives = 80/195 (41%), Gaps = 3/195 (1%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
EKI +VG+GL+G A A GY++ + D + A+ Q+++L G+ G+L
Sbjct: 5 EKIIVVGAGLMGTGIAYSCAISGYRILLVDANPSALDKAVG----QINSLVAAGVKLGKL 60
Query: 249 ---KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXX 419
+ ++ + +L A + E E +D+K + D ++ I
Sbjct: 61 VEAAGKAALERLEAAIELDGRASDAALLIETATEKIDIKLAIIGKADELLPPEAIIASNT 120
Query: 420 XXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQP 599
+ +Q H NP + + LVE++ T ++ + + +G+
Sbjct: 121 SALSISELAAATRRPTQFAGMHFFNPVHKMKLVELIRGIETTQATVERLKAVTAALGKTS 180
Query: 600 VSLTREIDGFVLNRI 644
+ + E GF +R+
Sbjct: 181 I-VVNEAPGFTTSRM 194
>UniRef50_Q1NHB4 Cluster: Fatty oxidation complex, alpha subunit;
n=2; Proteobacteria|Rep: Fatty oxidation complex, alpha
subunit - Sphingomonas sp. SKA58
Length = 722
Score = 52.8 bits (121), Expect = 8e-06
Identities = 44/203 (21%), Positives = 85/203 (41%)
Frame = +3
Query: 57 KFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLL 236
KF+++K+G++G+G++G A + A+ G V + D + L L G L
Sbjct: 310 KFEAKKVGVLGAGMMGAGIAFVSANAGIDVVLIDRDTATAQKGKDYSAKVLGKLVEKGKL 369
Query: 237 RGELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXX 416
+ KA I + D A + G V E V E+ +K + + ++V+ I
Sbjct: 370 TQD-KADAVLARITPTDDFA-LLDGCDMVVEAVFEDTAIKAETTKKAEAVLPAQAIFASN 427
Query: 417 XXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQ 596
+ + Q I H +P + LVE++ T E K + + ++ +
Sbjct: 428 TSTLPISQLAQASRSPDQFIGLHFFSPVDRMGLVEVIMGKQTSKETLAKGLDFIAQLRKT 487
Query: 597 PVSLTREIDGFVLNRIQYAILDE 665
P+ + + GF +R+ ++ E
Sbjct: 488 PI-VVNDSRGFYTSRVFQMLIHE 509
>UniRef50_Q1LBV6 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=4; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Ralstonia metallidurans
(strain CH34 / ATCC 43123 / DSM 2839)
Length = 714
Score = 52.8 bits (121), Expect = 8e-06
Identities = 43/194 (22%), Positives = 83/194 (42%), Gaps = 2/194 (1%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
+++GI+G+G++G A A G + + DV D K L G+ +G++
Sbjct: 316 KRVGILGAGMMGAGIAYASAMRGIEAVLKDVSL----DHAGKGKLHSEKLLEKGVSKGKI 371
Query: 249 KASEQFQCIKGSTDLATA--VKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXX 422
S++ + ++ T A A + G + E V E +LK +V + + + +N +
Sbjct: 372 SPSKRDEVLQRITPTADASGLAGCDIIIEAVYEKRELKAEVTREAEPHLAENGLFASNTS 431
Query: 423 XXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPV 602
E I H +P +PLVEI+ T + +++IG+ P+
Sbjct: 432 TLPITGLAEASASPENFIGLHFFSPVDRMPLVEIIKGKKTSSRTLAHAIDFVKQIGKTPI 491
Query: 603 SLTREIDGFVLNRI 644
+ + GF +R+
Sbjct: 492 -VVNDSRGFFTSRV 504
>UniRef50_A6X670 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=1; Ochrobactrum anthropi ATCC 49188|Rep:
3-hydroxyacyl-CoA dehydrogenase NAD-binding -
Ochrobactrum anthropi (strain ATCC 49188 / DSM 6882 /
NCTC 12168)
Length = 659
Score = 52.4 bits (120), Expect = 1e-05
Identities = 49/201 (24%), Positives = 83/201 (41%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
IGI G+GL+G A+ + GY V Y+ A+ I + + G L E A
Sbjct: 297 IGIAGTGLMGSGIAVASLAAGYTVIGYETTAEAAAKGHARITDMIQKAVDTGRLSTE-AA 355
Query: 255 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 434
Q + S D+A A+ A V E V ++ +K +F+ LD+++ TI
Sbjct: 356 DAQRSKLSVSADMA-ALADADLVIEAVFDDFTVKASLFRELDALLPPATILATNTSYLNP 414
Query: 435 XXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTR 614
+V+ H +P + L+E+V T E +I + + +T
Sbjct: 415 DELAAVTNRTDRVLGLHFFSPANIMRLLEVVRCAETSDETLATGIAFARKIKKLSI-VTG 473
Query: 615 EIDGFVLNRIQYAILDEVWRL 677
+GF+ NR+ A E ++
Sbjct: 474 VCEGFIGNRMFSAYRTEAEKM 494
>UniRef50_Q9L6L5 Cluster: Fatty acid oxidation complex subunit alpha
[Includes: Enoyl-CoA
hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA
isomerase/3- hydroxybutyryl-CoA epimerase (EC 4.2.1.17)
(EC 5.3.3.8) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)]; n=42; Proteobacteria|Rep:
Fatty acid oxidation complex subunit alpha [Includes:
Enoyl-CoA
hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA
isomerase/3- hydroxybutyryl-CoA epimerase (EC 4.2.1.17)
(EC 5.3.3.8) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)] - Salmonella typhimurium
Length = 729
Score = 52.4 bits (120), Expect = 1e-05
Identities = 45/194 (23%), Positives = 79/194 (40%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
++ ++G+G++G A A G V + D+ K + + + L+ G + G L
Sbjct: 314 KQAAVLGAGIMGGGIAYQSAWKGVPVIMKDINDKSLNLGMTEAAKLLNKQLERGKIDG-L 372
Query: 249 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 428
K + I + D A + V V E V EN +KK V + V T+
Sbjct: 373 KLAGVISTIHPTLDYAGFDRVDVVV-EAVVENPKVKKAVLAETEQKVRPETVLASNTSTI 431
Query: 429 XXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
L+ H NP + +PLVEI+ + E K ++G+ P+ +
Sbjct: 432 PIGELASALERPENFCGMHFFNPVHRMPLVEIIRGEKSSDETIAKVVAWASKMGKTPI-V 490
Query: 609 TREIDGFVLNRIQY 650
+ GF +NR+ +
Sbjct: 491 VNDCPGFFVNRVLF 504
>UniRef50_Q89SH2 Cluster: Blr2428 protein; n=7; Rhizobiales|Rep:
Blr2428 protein - Bradyrhizobium japonicum
Length = 715
Score = 52.0 bits (119), Expect = 1e-05
Identities = 43/189 (22%), Positives = 84/189 (44%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
+ ++G+G +G A A G +V++ D+ A+ I A++ +L+ ++R +
Sbjct: 343 VHVIGAGAMGGDIAAWCAGQGLRVSLADMKAEPIAGAVKRAA-ELY----GKIIRKPTEV 397
Query: 255 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 434
+ + D V+ A V E VPE L+LK+KV+ L+ + I
Sbjct: 398 RDALDRLIPDMD-GEGVRNADLVIEAVPEKLELKQKVYAGLEPKMKPGAILATNTSSIPL 456
Query: 435 XXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTR 614
L +++ H NP + LVE+V +V ++ + I + P+++ +
Sbjct: 457 QDLRTTLARPDRLVGLHFFNPVSRLQLVEVVSHDGNDAQVLREALAFVGAIDRLPLAV-K 515
Query: 615 EIDGFVLNR 641
GF++NR
Sbjct: 516 SSPGFLVNR 524
>UniRef50_Q3JZL6 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putative;
n=7; Streptococcus agalactiae|Rep: 3-hydroxyacyl-CoA
dehydrogenase, putative - Streptococcus agalactiae
serotype Ia
Length = 377
Score = 52.0 bits (119), Expect = 1e-05
Identities = 34/132 (25%), Positives = 55/132 (41%)
Frame = +3
Query: 282 STDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXXEGLKH 461
S +L AV A V E VPE + +K+ ++ L V TI +
Sbjct: 162 SKNLDQAVSDADLVIEAVPETVSIKEDFYKQLAKVAPSKTIFATNSSTLVPSQFADITGR 221
Query: 462 KSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNR 641
+ + H N + +VEI+ T EV K+ ++IG P+ + +E G++LN
Sbjct: 222 PDKFLAMHFANNIWQNNIVEIMGHKGTDDEVIKEALTFSKDIGMVPLHIHKEQPGYILNS 281
Query: 642 IQYAILDEVWRL 677
I L+ L
Sbjct: 282 ILVPFLESALAL 293
Score = 33.1 bits (72), Expect = 7.2
Identities = 34/133 (25%), Positives = 63/133 (47%), Gaps = 6/133 (4%)
Frame = +3
Query: 15 LSCGTVASTVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIED 194
LS T ++ I + + + GSG++G A A G VT+YD+ + + E
Sbjct: 42 LSSKTFSNISIGGCNMTIKNLTVAGSGVLGSQIAFQAAYKGMSVTIYDINDEALNKGKER 101
Query: 195 IKYQLHTLENDGLLRGELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDL-----KK 359
IK +L + + + S++ + IK + +L ++ +F+ + V ++LDL +
Sbjct: 102 IK-KLAKVYQSEIETAKEAYSDKAKSIKYNKNLLPSL-DHIFLSK-VADSLDLIADLPNQ 158
Query: 360 KVF-QNLDSVVDD 395
F +NLD V D
Sbjct: 159 ITFSKNLDQAVSD 171
>UniRef50_Q1Z537 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Photobacterium profundum 3TCK|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Photobacterium profundum 3TCK
Length = 713
Score = 52.0 bits (119), Expect = 1e-05
Identities = 44/194 (22%), Positives = 84/194 (43%), Gaps = 4/194 (2%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDV----VAKQITDAIEDIKYQLHTLENDGLLR 239
++G++G+G++G A + A G V + D+ +A +T+A + + Q+ L
Sbjct: 314 EVGVIGAGIMGGGIAYVTADKGADVVMKDINKAGLALGLTEANKLLAAQVERGRKKPLAM 373
Query: 240 GELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXX 419
GE Q ST + + E V EN +K+ V L+ V + T+
Sbjct: 374 GETLNRIQ------STLYNQPLTSNDLIIEAVVENPKIKEAVLAELEQVSPNATLASNTS 427
Query: 420 XXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQP 599
+ LK H NP + +PLVE++ T + + + + ++G+ P
Sbjct: 428 TLMISGLA-QALKKPENFCGIHFFNPVHKMPLVEVIRGEQTSDQTITQAVKYVSQLGKTP 486
Query: 600 VSLTREIDGFVLNR 641
+ + + GF++NR
Sbjct: 487 I-VVNDCAGFLVNR 499
>UniRef50_Q4DMG1 Cluster: Short chain 3-hydroxyacyl-coa
dehydrogenase, putative; n=2; Trypanosoma cruzi|Rep:
Short chain 3-hydroxyacyl-coa dehydrogenase, putative -
Trypanosoma cruzi
Length = 320
Score = 52.0 bits (119), Expect = 1e-05
Identities = 42/201 (20%), Positives = 80/201 (39%), Gaps = 4/201 (1%)
Frame = +3
Query: 54 SKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGL 233
S+ + + G G +G A + A G TV +V ++++ + + I+ L +
Sbjct: 28 SRMFFNSVAVWGGGTMGSGIAQVNAQAGIPTTVVEVSQERLSASRKSIESSLSRIGKKQY 87
Query: 234 LRGELK----ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNT 401
+ K E I +TD A A + E + E++D KK +++ +D +
Sbjct: 88 PGDDQKMKAFVDETVSRITFTTDERLAASNASLIVEAILEDIDAKKVLWRKVDGMAPKEC 147
Query: 402 IXXXXXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIME 581
+ + H +P + LVE+V A T + E +
Sbjct: 148 VFCTNTSSLSVGEQAAVTGRPDRFAGLHFFSPVPMMKLVEVVKAAKTSQSTLDRILEYAK 207
Query: 582 EIGQQPVSLTREIDGFVLNRI 644
+ +QPV T + GF++NR+
Sbjct: 208 MLNKQPVMAT-DTKGFIVNRL 227
>UniRef50_O28262 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 281
Score = 52.0 bits (119), Expect = 1e-05
Identities = 53/202 (26%), Positives = 89/202 (44%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 251
K+ ++G+GL+GR A+ AS ++V + DV K + A E I EL
Sbjct: 2 KVFVIGAGLMGRGIAIAIASK-HEVVLQDVSEKALEAAREQIPE-------------ELL 47
Query: 252 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 431
+ +F T VK V E V E+L+ K +V + ++ + N
Sbjct: 48 SKIEF------TTTLEKVKDCDIVMEAVFEDLNTKVEVLREVERLT--NAPLCSNTSVIS 99
Query: 432 XXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLT 611
E L S+ + H +NPP+ +PLVEIV + +T + + E+G++ V
Sbjct: 100 VDDIAERLDSPSRFLGVHWMNPPHVMPLVEIVISRFTDSKTVAFVEGFLRELGKEVVVCK 159
Query: 612 REIDGFVLNRIQYAILDEVWRL 677
+ ++NR A+L E R+
Sbjct: 160 GQ---SLVNRFNAAVLSEASRM 178
>UniRef50_Q8FRN7 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=1; Corynebacterium efficiens|Rep: Putative
3-hydroxyacyl-CoA dehydrogenase - Corynebacterium
efficiens
Length = 755
Score = 51.6 bits (118), Expect = 2e-05
Identities = 48/191 (25%), Positives = 79/191 (41%), Gaps = 3/191 (1%)
Frame = +3
Query: 81 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHT-LENDGLLRGELKAS 257
++G+G +G A L A+ G VT+ D + D + L ++ R E +
Sbjct: 17 VIGAGSMGAGIATLLANAGITVTLLDRHSGDPEDPNRLAESGLERQIQRGAFYRPEFSSR 76
Query: 258 EQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXX 437
Q I T A+ A ++ E V E+L +K F+ ++ ++
Sbjct: 77 IQTGNIVDDT---AALTRADWIIEAVFEDLTVKHDTFRLIEEHRSPGSLVSSNTSTIPLA 133
Query: 438 XXXE--GLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLT 611
E G + + H NPP + LVE+V P T P+ A I+E+ + V
Sbjct: 134 QLTEVMGTPMRLDFAIVHFFNPPTTMRLVELVTGPDTTPKTATDLTRIIEQQLGKVVLHC 193
Query: 612 REIDGFVLNRI 644
R+ GF+ NRI
Sbjct: 194 RDTPGFIANRI 204
>UniRef50_Q3IIH0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4;
Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Pseudoalteromonas haloplanktis (strain TAC 125)
Length = 281
Score = 51.6 bits (118), Expect = 2e-05
Identities = 42/201 (20%), Positives = 87/201 (43%), Gaps = 3/201 (1%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIED---IKYQLHTLENDGLLRG 242
++ I+GSG + + + +V+ +++A+ A+ + L G +
Sbjct: 2 EVSIIGSGTMATGITQVLC-LSNEVSKVNLIARTEEKALASKSTCAKNISRLARKGKISD 60
Query: 243 ELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXX 422
E +AS + + + +L V + + E + E+ K +F L ++D+ I
Sbjct: 61 E-QASFALEKLYCNAELVAVVNSDLII-EAIVEDFTAKMVLFSKLAEFINDSVIVASNTS 118
Query: 423 XXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPV 602
L + V+ H NP + LVEI+ T P + + + + +G+ PV
Sbjct: 119 SLSITAFASVLPNPQNVVGLHFFNPAPIMELVEIIVGHETAPAKIQLLQGLTKNLGKVPV 178
Query: 603 SLTREIDGFVLNRIQYAILDE 665
+ +E GFV+NR+ +++E
Sbjct: 179 -VVQEAPGFVVNRMLIPMINE 198
>UniRef50_Q11BV6 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Mesorhizobium sp. BNC1|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Mesorhizobium sp. (strain BNC1)
Length = 677
Score = 51.6 bits (118), Expect = 2e-05
Identities = 45/194 (23%), Positives = 81/194 (41%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 251
++G++G+G +G A+ + G V + D +T A +K L LE G L+
Sbjct: 287 RLGVIGAGTMGVGLAVSLLAAGKSVVLIDKDDLALTRASAAVKSGLARLERGGKLKEAPD 346
Query: 252 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 431
A+ + S +L +AV+ V E V E+ ++K V +L + + +
Sbjct: 347 AA--LARLVASKEL-SAVENCEVVIEAVVESFEVKSAVLSDLHARLSPGAMVVSNTSYLD 403
Query: 432 XXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLT 611
+ + H P + LVE+VP P T +++ ++G+ V
Sbjct: 404 IAELARASGRPDRFLGLHFFAPVPVMTLVEVVPLPETSSHTLTVATQLVRDMGKVAVR-A 462
Query: 612 REIDGFVLNRIQYA 653
+GF+ NRI A
Sbjct: 463 GPCNGFLGNRIYAA 476
>UniRef50_A3T2M8 Cluster: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase;
n=4; cellular organisms|Rep: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase -
Sulfitobacter sp. NAS-14.1
Length = 695
Score = 51.2 bits (117), Expect = 3e-05
Identities = 46/190 (24%), Positives = 80/190 (42%), Gaps = 2/190 (1%)
Frame = +3
Query: 81 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK--A 254
+VG G +G + A A+ G VTV + A A ++ L L + G+ RG L A
Sbjct: 291 VVGGGNMGAAIAYTLATAGISVTVVERSASSAEWASKN----LQKLIDQGISRGILSVDA 346
Query: 255 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 434
++ + + A+ E E+ +K + L+ + TI
Sbjct: 347 AKTVEDRLVTVSGYDALPPTDLAIEAAFEDFAVKTAILTELEGALPPETIIATNTSYLDV 406
Query: 435 XXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTR 614
+GLKH ++ + H +P + + L+E+V + T + +G+ PV L+
Sbjct: 407 NRLSDGLKHPARFVGMHFFSPAHIMKLLEVVRSDRTSDGTLGAALVLAHRLGKIPV-LSG 465
Query: 615 EIDGFVLNRI 644
DGF+ NRI
Sbjct: 466 VCDGFIGNRI 475
>UniRef50_Q0YNJ7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Geobacter sp. FRC-32|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Geobacter sp. FRC-32
Length = 311
Score = 50.8 bits (116), Expect = 3e-05
Identities = 45/196 (22%), Positives = 78/196 (39%), Gaps = 5/196 (2%)
Frame = +3
Query: 72 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTL-----ENDGLL 236
K I+G+G++GR W A G++V +D + + + + T +D
Sbjct: 2 KFAILGTGIMGRGWITQCAMSGHEVHCHDASPQTLAGTVAGCEKLAATAAKKFKHDDPNF 61
Query: 237 RGELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXX 416
+ KG+ A KG E + E+L LK V + + + +
Sbjct: 62 VSNAMGKIRVHNEKGA--FIDAAKGCDVFLEVIFEDLKLKCSVLADYLPQLPPSVVFWSN 119
Query: 417 XXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQ 596
+ + IV+H +NP +P VE+VP T E + TR+ + + +
Sbjct: 120 SSSLDIDPMAQAGGRPDRSIVTHGMNPVPLMPGVEVVPGAKTSSETIEFTRQTLLNMKKA 179
Query: 597 PVSLTREIDGFVLNRI 644
P L I GF +NR+
Sbjct: 180 PF-LAPNIPGFWVNRL 194
>UniRef50_A3VIL7 Cluster: Enoyl-CoA
hydratase/isomerase:3-hydroxyacyl-CoA dehydrogenase,3-
hydroxyacyl-CoA dehydrogenase, NAD-binding; n=1;
Rhodobacterales bacterium HTCC2654|Rep: Enoyl-CoA
hydratase/isomerase:3-hydroxyacyl-CoA dehydrogenase,3-
hydroxyacyl-CoA dehydrogenase, NAD-binding -
Rhodobacterales bacterium HTCC2654
Length = 695
Score = 50.8 bits (116), Expect = 3e-05
Identities = 48/195 (24%), Positives = 76/195 (38%), Gaps = 2/195 (1%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
+G+VG+G + R AM G VT VA + AI ++ ++ D + G L
Sbjct: 302 VGVVGAGALARDVAMAALKAGVPVT----VALEDDTAITRVRGRIERAFGDAVEAGTLSG 357
Query: 255 SEQFQCIK--GSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 428
E+ ++ + D A+ + E + E+ K + L V +TI
Sbjct: 358 RERDDRLRRLNTADDYGALDDKDVIIEALAEDSVRKTQALGQLSQVAAGHTIFASSTAEC 417
Query: 429 XXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSL 608
+ H + P LVEI PA T+PE + +G+ PV L
Sbjct: 418 DIETLAGASGRPDRFAAMHFIAPADANRLVEIAPARGTRPEALMTLIRLARAMGKGPV-L 476
Query: 609 TREIDGFVLNRIQYA 653
T G V NR++ A
Sbjct: 477 TGARQGLVYNRMRQA 491
>UniRef50_A6FFH1 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenase;
n=1; Moritella sp. PE36|Rep: Probable 3-hydroxyacyl-CoA
dehydrogenase - Moritella sp. PE36
Length = 698
Score = 50.4 bits (115), Expect = 4e-05
Identities = 49/205 (23%), Positives = 83/205 (40%)
Frame = +3
Query: 63 KSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRG 242
K K+G++G+G++G A AS G V + D+ + A+ Y L N L
Sbjct: 312 KFSKVGVLGAGMMGAGIAYALASHGITVILKDI---SLEKAVFAKSYTASILANCKL-ED 367
Query: 243 ELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXX 422
E K + Q I S + A + G V E V E+ +K + + + V D I
Sbjct: 368 EEKCTI-LQRITPSKESADLI-GCDMVIEAVFEDRKVKNQAITEILTAVGDELIMASNTS 425
Query: 423 XXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPV 602
I H +P +PLVEI+ T +++ +IG+ P+
Sbjct: 426 TLPISSLATASTKPENFIGLHFFSPVDKMPLVEIIKGDKTSSATLAAAYDLVIQIGKVPI 485
Query: 603 SLTREIDGFVLNRIQYAILDEVWRL 677
+ + GF +R+ + + E R+
Sbjct: 486 -VVNDSRGFFTSRVFFTYVSEGMRM 509
>UniRef50_A0K022 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=9; Actinomycetales|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Arthrobacter sp. (strain FB24)
Length = 290
Score = 50.4 bits (115), Expect = 4e-05
Identities = 46/201 (22%), Positives = 77/201 (38%)
Frame = +3
Query: 75 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 254
+G++G G +G A F G V V + A E ++ G G L
Sbjct: 14 VGVLGGGRMGAGIAHAFLINGANVLVVERDEASAEAARERVESAAAKSIERGATDGNL-- 71
Query: 255 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 434
E + + D K V E VPE+ +LK + +++ + D+
Sbjct: 72 DEMVSRLSVTVDYDD-FKDRELVVEAVPEDWELKVASLREIEARLSDDAYLASNTSSLSV 130
Query: 435 XXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTR 614
LK + H NP L+E+V T P++A + +E +G+ V +
Sbjct: 131 NGLARELKRPGNFLGLHFFNPVPASTLIEVVLGEQTSPDLAAAAKRWVEALGKTAV-VVN 189
Query: 615 EIDGFVLNRIQYAILDEVWRL 677
+ GF +R+ AI E R+
Sbjct: 190 DAPGFASSRLGVAIALEAMRM 210
>UniRef50_Q67QQ5 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=1; Symbiobacterium thermophilum|Rep: Putative
3-hydroxyacyl-CoA dehydrogenase - Symbiobacterium
thermophilum
Length = 190
Score = 50.0 bits (114), Expect = 6e-05
Identities = 40/184 (21%), Positives = 73/184 (39%), Gaps = 2/184 (1%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
E+I ++G + G A L A GY +++ + +A ++ +L + +G G
Sbjct: 2 ERITVIGGTVAGVEIAALMARAGYATCLHEPDQAALAEAGRRLQDRLLGRQGEG---GGA 58
Query: 249 KASEQFQCIKGSTDLA--TAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXX 422
+ Q ++ + AV A V E +L K+++F LDS + I
Sbjct: 59 ASVAQLAAVRVRLEAVPEVAVADADLVIEASSVDLPGKRELFARLDSFAPAHAILATCSP 118
Query: 423 XXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPV 602
+V+ +PP P V ++ P PEV E++ G++P+
Sbjct: 119 TISSAYLAAATSRPDRVVSLGFFSPPLAPPAVAVIQEPHLAPEVVAAVAEVVWRTGREPL 178
Query: 603 SLTR 614
L R
Sbjct: 179 LLRR 182
>UniRef50_Q1INT0 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=1; Acidobacteria bacterium
Ellin345|Rep: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor - Acidobacteria bacterium (strain
Ellin345)
Length = 806
Score = 50.0 bits (114), Expect = 6e-05
Identities = 46/209 (22%), Positives = 93/209 (44%), Gaps = 9/209 (4%)
Frame = +3
Query: 69 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 248
EK+ ++G+G +G A FA+ G ++D+V DA + ++ D + +
Sbjct: 6 EKVAVLGAGTMGARIAAHFANAGIPSYLFDIVPP---DADGPARNKIAAAGLDAAKKSKP 62
Query: 249 KASEQFQCIKGST-----DLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXX 413
A K T D + ++ E V ENL+LK+ + + +++V ++
Sbjct: 63 AAFFHPDLAKLVTVGNFEDDLKKLGECDWIIEAVVENLELKRALLKKVEAVRKPGSLITT 122
Query: 414 XXXXXXXXXXXEGLKH--KSQVIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIME-E 584
EG + +H NPP Y+ L+E++P P T P+ + + + +
Sbjct: 123 NTSGLPVSKISEGFSEDFRRNWFGTHFFNPPRYMRLLELIPTPDTDPKAMEAVAHLGDVQ 182
Query: 585 IGQQPVSLTREIDGFVLNRI-QYAILDEV 668
+G+ V ++ F+ NRI +++L+ +
Sbjct: 183 LGKGIVH-AKDTPNFIGNRIGTFSVLNVI 210
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 714,616,894
Number of Sequences: 1657284
Number of extensions: 14506037
Number of successful extensions: 46215
Number of sequences better than 10.0: 423
Number of HSP's better than 10.0 without gapping: 44179
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 46001
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 58853922985
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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