Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P01_pT_J20
(704 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U58087-1|AAC50544.1| 752|Homo sapiens Hs-CUL-1 protein. 336 3e-92
BC125120-1|AAI25121.1| 776|Homo sapiens cullin 1 protein. 336 3e-92
BC125119-1|AAI25120.1| 776|Homo sapiens cullin 1 protein. 336 3e-92
AF062536-1|AAC36681.1| 776|Homo sapiens cullin 1 protein. 336 3e-92
AC006323-3|AAS02034.1| 513|Homo sapiens unknown protein. 336 3e-92
BX537409-1|CAD97651.1| 776|Homo sapiens hypothetical protein pr... 335 8e-92
U83410-1|AAC51190.1| 745|Homo sapiens CUL-2 protein. 178 1e-44
BC110901-1|AAI10902.1| 745|Homo sapiens CUL2 protein protein. 178 1e-44
BC009591-1|AAH09591.1| 745|Homo sapiens cullin 2 protein. 178 1e-44
AL392046-2|CAI13163.1| 745|Homo sapiens cullin 2 protein. 178 1e-44
AL392046-1|CAI13162.1| 688|Homo sapiens cullin 2 protein. 178 1e-44
AF126404-1|AAD23581.1| 745|Homo sapiens cullin 2 protein. 178 1e-44
U58088-1|AAC50545.1| 651|Homo sapiens Hs-CUL-2 protein. 176 6e-44
U58091-1|AAC50548.1| 288|Homo sapiens Hs-CUL-4B protein. 131 2e-30
BX537787-1|CAD97843.1| 895|Homo sapiens hypothetical protein pr... 131 2e-30
AL451005-1|CAI41370.1| 913|Homo sapiens cullin 4B protein. 131 2e-30
AF212995-1|AAK16812.1| 782|Homo sapiens cullin CUL4B protein. 131 2e-30
AC002476-3|AAB67315.1| 652|Homo sapiens WUGSC:H_DJ318C15.2 prot... 131 2e-30
AB014595-1|BAA31670.2| 781|Homo sapiens KIAA0695 protein protein. 131 2e-30
BC036216-1|AAH36216.1| 913|Homo sapiens cullin 4B protein. 131 3e-30
AY365125-1|AAR13073.1| 895|Homo sapiens cullin 4B protein. 131 3e-30
U58090-1|AAC50547.1| 421|Homo sapiens Hs-CUL-4A protein. 122 1e-27
BC008308-1|AAH08308.2| 759|Homo sapiens cullin 4A protein. 122 1e-27
AY365124-1|AAR13072.1| 759|Homo sapiens cullin 4A protein. 122 1e-27
AL136221-5|CAI13795.1| 659|Homo sapiens cullin 4A protein. 122 1e-27
AL136221-4|CAM18410.1| 759|Homo sapiens cullin 4A protein. 122 1e-27
AF077188-1|AAD45191.1| 659|Homo sapiens cullin 4A protein. 122 1e-27
AB178950-1|BAD93235.1| 759|Homo sapiens cullin-4A protein. 122 1e-27
AB012193-1|BAA33146.1| 524|Homo sapiens cullin-4A protein. 122 1e-27
U58089-1|AAC50546.1| 577|Homo sapiens Hs-CUL-3 protein. 117 4e-26
BC092409-1|AAH92409.1| 768|Homo sapiens cullin 3 protein. 117 4e-26
BC039598-1|AAH39598.1| 768|Homo sapiens cullin 3 protein. 117 4e-26
AF064087-1|AAC36304.1| 768|Homo sapiens cullin 3 protein. 117 4e-26
AF062537-1|AAC36682.1| 768|Homo sapiens cullin 3 protein. 117 4e-26
AF052147-1|AAC28621.1| 343|Homo sapiens cul-3 protein. 117 4e-26
AC073052-1|AAX93287.1| 746|Homo sapiens unknown protein. 117 4e-26
AB014517-1|BAA31592.2| 786|Homo sapiens KIAA0617 protein protein. 117 4e-26
BC031844-1|AAH31844.1| 373|Homo sapiens CUL3 protein protein. 117 5e-26
AY337761-1|AAQ01660.1| 744|Homo sapiens cullin 3 isoform protein. 116 6e-26
BC063306-1|AAH63306.1| 780|Homo sapiens cullin 5 protein. 94 4e-19
AF327710-1|AAK07472.1| 780|Homo sapiens cullin 5 protein. 94 4e-19
AF017061-1|AAB70253.1| 781|Homo sapiens vasopressin-activated c... 94 4e-19
X81882-1|CAA57465.1| 780|Homo sapiens vasopressin activated cal... 92 2e-18
AL392046-3|CAI13164.1| 706|Homo sapiens cullin 2 protein. 82 2e-15
BC002879-1|AAH02879.2| 964|Homo sapiens PARC protein protein. 44 5e-04
AY145132-1|AAN61516.1| 2517|Homo sapiens p53-associated parkin-l... 44 5e-04
AL133375-1|CAI20204.1| 2518|Homo sapiens RP3-330M21.2 protein. 44 5e-04
AJ318215-1|CAC85756.1| 2517|Homo sapiens putative E3 ubiquitin l... 44 5e-04
AB014608-1|BAA31683.3| 1753|Homo sapiens KIAA0708 protein. 44 5e-04
BC062749-1|AAH62749.1| 383|Homo sapiens CCDC73 protein protein. 32 2.3
BC032503-1|AAH32503.1| 822|Homo sapiens anaphase promoting comp... 32 2.3
BC001579-1|AAH01579.1| 577|Homo sapiens ANAPC2 protein protein. 32 2.3
AL929554-12|CAH72881.1| 822|Homo sapiens anaphase promoting com... 32 2.3
AF191337-1|AAF05751.1| 822|Homo sapiens anaphase-promoting comp... 32 2.3
AB037827-1|BAA92644.1| 571|Homo sapiens KIAA1406 protein protein. 32 2.3
AK129846-1|BAC85241.1| 236|Homo sapiens protein ( Homo sapiens ... 31 3.0
U90920-1|AAB81012.1| 1261|Homo sapiens PTPL1-associated RhoGAP p... 31 4.0
BC047885-1|AAH47885.1| 426|Homo sapiens SLK protein protein. 31 5.3
AL135842-3|CAI23350.1| 118|Homo sapiens late cornified envelope... 30 7.0
D86959-1|BAA13195.2| 1164|Homo sapiens KIAA0204 protein protein. 30 9.3
BC129951-1|AAI29952.1| 854|Homo sapiens MAP3K6 protein protein. 30 9.3
BC129950-1|AAI29951.1| 854|Homo sapiens MAP3K6 protein protein. 30 9.3
BC111565-1|AAI11566.1| 1204|Homo sapiens SLK protein protein. 30 9.3
BC109032-1|AAI09033.1| 441|Homo sapiens MAP3K6 protein protein. 30 9.3
BC064804-1|AAH64804.1| 617|Homo sapiens SLK protein protein. 30 9.3
BC047762-1|AAH47762.1| 614|Homo sapiens SLK protein protein. 30 9.3
BC015914-1|AAH15914.1| 797|Homo sapiens MAP3K6 protein protein. 30 9.3
AL663123-5|CAI14778.1| 797|Homo sapiens mitogen-activated prote... 30 9.3
AL663123-4|CAM12869.1| 1288|Homo sapiens mitogen-activated prote... 30 9.3
AL360170-2|CAH70404.1| 1235|Homo sapiens Ste20-related serine\/t... 30 9.3
AL360170-1|CAH70403.1| 1204|Homo sapiens Ste20-related serine\/t... 30 9.3
AL138761-2|CAI12395.1| 1235|Homo sapiens Ste20-related serine\/t... 30 9.3
AL138761-1|CAI12396.1| 1204|Homo sapiens Ste20-related serine\/t... 30 9.3
AF273048-1|AAG34908.1| 1235|Homo sapiens CTCL tumor antigen se20... 30 9.3
AF100318-1|AAD05304.1| 1011|Homo sapiens mitogen-activated prote... 30 9.3
AB208805-1|BAD92042.1| 1192|Homo sapiens mitogen-activated prote... 30 9.3
AB167411-1|BAD12485.1| 1288|Homo sapiens apoptosis signal-regula... 30 9.3
AB002804-1|BAA19655.1| 1204|Homo sapiens hSLK protein. 30 9.3
>U58087-1|AAC50544.1| 752|Homo sapiens Hs-CUL-1 protein.
Length = 752
Score = 336 bits (827), Expect = 3e-92
Identities = 165/225 (73%), Positives = 188/225 (83%), Gaps = 5/225 (2%)
Frame = -2
Query: 700 SFQLPTEXERSVHRFTTFYSSQHSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAVL 521
+F LP+E ERS RFT FY+S+HSGRKL WLY +SKGEL+TNCFKNRYTLQASTFQMA+L
Sbjct: 528 TFALPSELERSYQRFTAFYASRHSGRKLTWLYQLSKGELVTNCFKNRYTLQASTFQMAIL 587
Query: 520 LQYNDNTSWTVRQLEQHTGIKGDFLIQVLQILLKAKLLVCQE-----DEAELGENSVVDL 356
LQYN ++TV+QL T IK D L QVLQILLK+KLLV ++ DE EL ++++ L
Sbjct: 588 LQYNTEDAYTVQQLTDSTQIKMDILAQVLQILLKSKLLVLEDENANVDEVELKPDTLIKL 647
Query: 355 YSGYKNKKLRVNINIPLKTELKVEQEATHKHIEEDRKMLIQAAIVRIMKTRKTLKHQHLV 176
Y GYKNKKLRVNIN+P+KTE K EQE THK+IEEDRK+LIQAAIVRIMK RK LKHQ L+
Sbjct: 648 YLGYKNKKLRVNINVPMKTEQKQEQETTHKNIEEDRKLLIQAAIVRIMKMRKVLKHQQLL 707
Query: 175 VEVLNQLSSRFKPRVPVIKKCIDILIEKEYLERTEGEKDTYSYLA 41
EVL QLSSRFKPRVPVIKKCIDILIEKEYLER +GEKDTYSYLA
Sbjct: 708 GEVLTQLSSRFKPRVPVIKKCIDILIEKEYLERVDGEKDTYSYLA 752
>BC125120-1|AAI25121.1| 776|Homo sapiens cullin 1 protein.
Length = 776
Score = 336 bits (827), Expect = 3e-92
Identities = 165/225 (73%), Positives = 188/225 (83%), Gaps = 5/225 (2%)
Frame = -2
Query: 700 SFQLPTEXERSVHRFTTFYSSQHSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAVL 521
+F LP+E ERS RFT FY+S+HSGRKL WLY +SKGEL+TNCFKNRYTLQASTFQMA+L
Sbjct: 552 TFALPSELERSYQRFTAFYASRHSGRKLTWLYQLSKGELVTNCFKNRYTLQASTFQMAIL 611
Query: 520 LQYNDNTSWTVRQLEQHTGIKGDFLIQVLQILLKAKLLVCQE-----DEAELGENSVVDL 356
LQYN ++TV+QL T IK D L QVLQILLK+KLLV ++ DE EL ++++ L
Sbjct: 612 LQYNTEDAYTVQQLTDSTQIKMDILAQVLQILLKSKLLVLEDENANVDEVELKPDTLIKL 671
Query: 355 YSGYKNKKLRVNINIPLKTELKVEQEATHKHIEEDRKMLIQAAIVRIMKTRKTLKHQHLV 176
Y GYKNKKLRVNIN+P+KTE K EQE THK+IEEDRK+LIQAAIVRIMK RK LKHQ L+
Sbjct: 672 YLGYKNKKLRVNINVPMKTEQKQEQETTHKNIEEDRKLLIQAAIVRIMKMRKVLKHQQLL 731
Query: 175 VEVLNQLSSRFKPRVPVIKKCIDILIEKEYLERTEGEKDTYSYLA 41
EVL QLSSRFKPRVPVIKKCIDILIEKEYLER +GEKDTYSYLA
Sbjct: 732 GEVLTQLSSRFKPRVPVIKKCIDILIEKEYLERVDGEKDTYSYLA 776
>BC125119-1|AAI25120.1| 776|Homo sapiens cullin 1 protein.
Length = 776
Score = 336 bits (827), Expect = 3e-92
Identities = 165/225 (73%), Positives = 188/225 (83%), Gaps = 5/225 (2%)
Frame = -2
Query: 700 SFQLPTEXERSVHRFTTFYSSQHSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAVL 521
+F LP+E ERS RFT FY+S+HSGRKL WLY +SKGEL+TNCFKNRYTLQASTFQMA+L
Sbjct: 552 TFALPSELERSYQRFTAFYASRHSGRKLTWLYQLSKGELVTNCFKNRYTLQASTFQMAIL 611
Query: 520 LQYNDNTSWTVRQLEQHTGIKGDFLIQVLQILLKAKLLVCQE-----DEAELGENSVVDL 356
LQYN ++TV+QL T IK D L QVLQILLK+KLLV ++ DE EL ++++ L
Sbjct: 612 LQYNTEDAYTVQQLTDSTQIKMDILAQVLQILLKSKLLVLEDENANVDEVELKPDTLIKL 671
Query: 355 YSGYKNKKLRVNINIPLKTELKVEQEATHKHIEEDRKMLIQAAIVRIMKTRKTLKHQHLV 176
Y GYKNKKLRVNIN+P+KTE K EQE THK+IEEDRK+LIQAAIVRIMK RK LKHQ L+
Sbjct: 672 YLGYKNKKLRVNINVPMKTEQKQEQETTHKNIEEDRKLLIQAAIVRIMKMRKVLKHQQLL 731
Query: 175 VEVLNQLSSRFKPRVPVIKKCIDILIEKEYLERTEGEKDTYSYLA 41
EVL QLSSRFKPRVPVIKKCIDILIEKEYLER +GEKDTYSYLA
Sbjct: 732 GEVLTQLSSRFKPRVPVIKKCIDILIEKEYLERVDGEKDTYSYLA 776
>AF062536-1|AAC36681.1| 776|Homo sapiens cullin 1 protein.
Length = 776
Score = 336 bits (827), Expect = 3e-92
Identities = 165/225 (73%), Positives = 188/225 (83%), Gaps = 5/225 (2%)
Frame = -2
Query: 700 SFQLPTEXERSVHRFTTFYSSQHSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAVL 521
+F LP+E ERS RFT FY+S+HSGRKL WLY +SKGEL+TNCFKNRYTLQASTFQMA+L
Sbjct: 552 TFALPSELERSYQRFTAFYASRHSGRKLTWLYQLSKGELVTNCFKNRYTLQASTFQMAIL 611
Query: 520 LQYNDNTSWTVRQLEQHTGIKGDFLIQVLQILLKAKLLVCQE-----DEAELGENSVVDL 356
LQYN ++TV+QL T IK D L QVLQILLK+KLLV ++ DE EL ++++ L
Sbjct: 612 LQYNTEDAYTVQQLTDSTQIKMDILAQVLQILLKSKLLVLEDENANVDEVELKPDTLIKL 671
Query: 355 YSGYKNKKLRVNINIPLKTELKVEQEATHKHIEEDRKMLIQAAIVRIMKTRKTLKHQHLV 176
Y GYKNKKLRVNIN+P+KTE K EQE THK+IEEDRK+LIQAAIVRIMK RK LKHQ L+
Sbjct: 672 YLGYKNKKLRVNINVPMKTEQKQEQETTHKNIEEDRKLLIQAAIVRIMKMRKVLKHQQLL 731
Query: 175 VEVLNQLSSRFKPRVPVIKKCIDILIEKEYLERTEGEKDTYSYLA 41
EVL QLSSRFKPRVPVIKKCIDILIEKEYLER +GEKDTYSYLA
Sbjct: 732 GEVLTQLSSRFKPRVPVIKKCIDILIEKEYLERVDGEKDTYSYLA 776
>AC006323-3|AAS02034.1| 513|Homo sapiens unknown protein.
Length = 513
Score = 336 bits (827), Expect = 3e-92
Identities = 165/225 (73%), Positives = 188/225 (83%), Gaps = 5/225 (2%)
Frame = -2
Query: 700 SFQLPTEXERSVHRFTTFYSSQHSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAVL 521
+F LP+E ERS RFT FY+S+HSGRKL WLY +SKGEL+TNCFKNRYTLQASTFQMA+L
Sbjct: 289 TFALPSELERSYQRFTAFYASRHSGRKLTWLYQLSKGELVTNCFKNRYTLQASTFQMAIL 348
Query: 520 LQYNDNTSWTVRQLEQHTGIKGDFLIQVLQILLKAKLLVCQE-----DEAELGENSVVDL 356
LQYN ++TV+QL T IK D L QVLQILLK+KLLV ++ DE EL ++++ L
Sbjct: 349 LQYNTEDAYTVQQLTDSTQIKMDILAQVLQILLKSKLLVLEDENANVDEVELKPDTLIKL 408
Query: 355 YSGYKNKKLRVNINIPLKTELKVEQEATHKHIEEDRKMLIQAAIVRIMKTRKTLKHQHLV 176
Y GYKNKKLRVNIN+P+KTE K EQE THK+IEEDRK+LIQAAIVRIMK RK LKHQ L+
Sbjct: 409 YLGYKNKKLRVNINVPMKTEQKQEQETTHKNIEEDRKLLIQAAIVRIMKMRKVLKHQQLL 468
Query: 175 VEVLNQLSSRFKPRVPVIKKCIDILIEKEYLERTEGEKDTYSYLA 41
EVL QLSSRFKPRVPVIKKCIDILIEKEYLER +GEKDTYSYLA
Sbjct: 469 GEVLTQLSSRFKPRVPVIKKCIDILIEKEYLERVDGEKDTYSYLA 513
>BX537409-1|CAD97651.1| 776|Homo sapiens hypothetical protein
protein.
Length = 776
Score = 335 bits (824), Expect = 8e-92
Identities = 164/225 (72%), Positives = 188/225 (83%), Gaps = 5/225 (2%)
Frame = -2
Query: 700 SFQLPTEXERSVHRFTTFYSSQHSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAVL 521
+F LP+E ERS RFT FY+S+HSGRKL WLY +SKGEL+TNCFKNRYTLQASTFQMA+L
Sbjct: 552 TFALPSELERSYQRFTAFYASRHSGRKLTWLYQLSKGELVTNCFKNRYTLQASTFQMAIL 611
Query: 520 LQYNDNTSWTVRQLEQHTGIKGDFLIQVLQILLKAKLLVCQE-----DEAELGENSVVDL 356
LQYN ++TV+QL T IK D L QVLQILLK+KLLV ++ DE EL ++++ L
Sbjct: 612 LQYNTEDAYTVQQLTDSTQIKMDILAQVLQILLKSKLLVLEDENANVDEVELKPDTLIKL 671
Query: 355 YSGYKNKKLRVNINIPLKTELKVEQEATHKHIEEDRKMLIQAAIVRIMKTRKTLKHQHLV 176
Y GYKNKKLRVNIN+P+KTE K EQE THK+IEEDRK+LIQAAIVRIMK RK L+HQ L+
Sbjct: 672 YLGYKNKKLRVNINVPMKTEQKQEQETTHKNIEEDRKLLIQAAIVRIMKMRKVLRHQQLL 731
Query: 175 VEVLNQLSSRFKPRVPVIKKCIDILIEKEYLERTEGEKDTYSYLA 41
EVL QLSSRFKPRVPVIKKCIDILIEKEYLER +GEKDTYSYLA
Sbjct: 732 GEVLTQLSSRFKPRVPVIKKCIDILIEKEYLERVDGEKDTYSYLA 776
>U83410-1|AAC51190.1| 745|Homo sapiens CUL-2 protein.
Length = 745
Score = 178 bits (434), Expect = 1e-44
Identities = 83/221 (37%), Positives = 135/221 (61%)
Frame = -2
Query: 703 TSFQLPTEXERSVHRFTTFYSSQHSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAV 524
++F +P E E+SV F FYS SGRKL WL+ + GE+ N Y +T+QMAV
Sbjct: 525 STFAIPQELEKSVQMFELFYSQHFSGRKLTWLHYLCTGEVKMNYLGKPYVAMVTTYQMAV 584
Query: 523 LLQYNDNTSWTVRQLEQHTGIKGDFLIQVLQILLKAKLLVCQEDEAELGENSVVDLYSGY 344
LL +N++ + + ++L+ T + L + ++ LL K++ ++ ++ S L +
Sbjct: 585 LLAFNNSETVSYKELQDSTQMNEKELTKTIKSLLDVKMINHDSEKEDIDAESSFSLNMNF 644
Query: 343 KNKKLRVNINIPLKTELKVEQEATHKHIEEDRKMLIQAAIVRIMKTRKTLKHQHLVVEVL 164
+K+ + I ++ + E E T ++EDRKM +QAAIVRIMK RK L+H L+ EV+
Sbjct: 645 SSKRTKFKITTSMQKDTPQEMEQTRSAVDEDRKMYLQAAIVRIMKARKVLRHNALIQEVI 704
Query: 163 NQLSSRFKPRVPVIKKCIDILIEKEYLERTEGEKDTYSYLA 41
+Q +RF P + +IKKCI++LI+K+Y+ER++ D YSY+A
Sbjct: 705 SQSRARFNPSISMIKKCIEVLIDKQYIERSQASADEYSYVA 745
>BC110901-1|AAI10902.1| 745|Homo sapiens CUL2 protein protein.
Length = 745
Score = 178 bits (434), Expect = 1e-44
Identities = 83/221 (37%), Positives = 135/221 (61%)
Frame = -2
Query: 703 TSFQLPTEXERSVHRFTTFYSSQHSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAV 524
++F +P E E+SV F FYS SGRKL WL+ + GE+ N Y +T+QMAV
Sbjct: 525 STFAIPQELEKSVQMFELFYSQHFSGRKLTWLHYLCTGEVKMNYLGKPYVAMVTTYQMAV 584
Query: 523 LLQYNDNTSWTVRQLEQHTGIKGDFLIQVLQILLKAKLLVCQEDEAELGENSVVDLYSGY 344
LL +N++ + + ++L+ T + L + ++ LL K++ ++ ++ S L +
Sbjct: 585 LLAFNNSETVSYKELQDSTQMNEKELTKTIKSLLDVKMINHDSEKEDIDAESSFSLNMNF 644
Query: 343 KNKKLRVNINIPLKTELKVEQEATHKHIEEDRKMLIQAAIVRIMKTRKTLKHQHLVVEVL 164
+K+ + I ++ + E E T ++EDRKM +QAAIVRIMK RK L+H L+ EV+
Sbjct: 645 SSKRTKFKITTSMQKDTPQEMEQTRSAVDEDRKMYLQAAIVRIMKARKVLRHNALIQEVI 704
Query: 163 NQLSSRFKPRVPVIKKCIDILIEKEYLERTEGEKDTYSYLA 41
+Q +RF P + +IKKCI++LI+K+Y+ER++ D YSY+A
Sbjct: 705 SQSRARFNPSISMIKKCIEVLIDKQYIERSQASADEYSYVA 745
>BC009591-1|AAH09591.1| 745|Homo sapiens cullin 2 protein.
Length = 745
Score = 178 bits (434), Expect = 1e-44
Identities = 83/221 (37%), Positives = 135/221 (61%)
Frame = -2
Query: 703 TSFQLPTEXERSVHRFTTFYSSQHSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAV 524
++F +P E E+SV F FYS SGRKL WL+ + GE+ N Y +T+QMAV
Sbjct: 525 STFAIPQELEKSVQMFELFYSQHFSGRKLTWLHYLCTGEVKMNYLGKPYVAMVTTYQMAV 584
Query: 523 LLQYNDNTSWTVRQLEQHTGIKGDFLIQVLQILLKAKLLVCQEDEAELGENSVVDLYSGY 344
LL +N++ + + ++L+ T + L + ++ LL K++ ++ ++ S L +
Sbjct: 585 LLAFNNSETVSYKELQDSTQMNEKELTKTIKSLLDVKMINHDSEKEDIDAESSFSLNMNF 644
Query: 343 KNKKLRVNINIPLKTELKVEQEATHKHIEEDRKMLIQAAIVRIMKTRKTLKHQHLVVEVL 164
+K+ + I ++ + E E T ++EDRKM +QAAIVRIMK RK L+H L+ EV+
Sbjct: 645 SSKRTKFKITTSMQKDTPQEMEQTRSAVDEDRKMYLQAAIVRIMKARKVLRHNALIQEVI 704
Query: 163 NQLSSRFKPRVPVIKKCIDILIEKEYLERTEGEKDTYSYLA 41
+Q +RF P + +IKKCI++LI+K+Y+ER++ D YSY+A
Sbjct: 705 SQSRARFNPSISMIKKCIEVLIDKQYIERSQASADEYSYVA 745
>AL392046-2|CAI13163.1| 745|Homo sapiens cullin 2 protein.
Length = 745
Score = 178 bits (434), Expect = 1e-44
Identities = 83/221 (37%), Positives = 135/221 (61%)
Frame = -2
Query: 703 TSFQLPTEXERSVHRFTTFYSSQHSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAV 524
++F +P E E+SV F FYS SGRKL WL+ + GE+ N Y +T+QMAV
Sbjct: 525 STFAIPQELEKSVQMFELFYSQHFSGRKLTWLHYLCTGEVKMNYLGKPYVAMVTTYQMAV 584
Query: 523 LLQYNDNTSWTVRQLEQHTGIKGDFLIQVLQILLKAKLLVCQEDEAELGENSVVDLYSGY 344
LL +N++ + + ++L+ T + L + ++ LL K++ ++ ++ S L +
Sbjct: 585 LLAFNNSETVSYKELQDSTQMNEKELTKTIKSLLDVKMINHDSEKEDIDAESSFSLNMNF 644
Query: 343 KNKKLRVNINIPLKTELKVEQEATHKHIEEDRKMLIQAAIVRIMKTRKTLKHQHLVVEVL 164
+K+ + I ++ + E E T ++EDRKM +QAAIVRIMK RK L+H L+ EV+
Sbjct: 645 SSKRTKFKITTSMQKDTPQEMEQTRSAVDEDRKMYLQAAIVRIMKARKVLRHNALIQEVI 704
Query: 163 NQLSSRFKPRVPVIKKCIDILIEKEYLERTEGEKDTYSYLA 41
+Q +RF P + +IKKCI++LI+K+Y+ER++ D YSY+A
Sbjct: 705 SQSRARFNPSISMIKKCIEVLIDKQYIERSQASADEYSYVA 745
>AL392046-1|CAI13162.1| 688|Homo sapiens cullin 2 protein.
Length = 688
Score = 178 bits (434), Expect = 1e-44
Identities = 83/221 (37%), Positives = 135/221 (61%)
Frame = -2
Query: 703 TSFQLPTEXERSVHRFTTFYSSQHSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAV 524
++F +P E E+SV F FYS SGRKL WL+ + GE+ N Y +T+QMAV
Sbjct: 468 STFAIPQELEKSVQMFELFYSQHFSGRKLTWLHYLCTGEVKMNYLGKPYVAMVTTYQMAV 527
Query: 523 LLQYNDNTSWTVRQLEQHTGIKGDFLIQVLQILLKAKLLVCQEDEAELGENSVVDLYSGY 344
LL +N++ + + ++L+ T + L + ++ LL K++ ++ ++ S L +
Sbjct: 528 LLAFNNSETVSYKELQDSTQMNEKELTKTIKSLLDVKMINHDSEKEDIDAESSFSLNMNF 587
Query: 343 KNKKLRVNINIPLKTELKVEQEATHKHIEEDRKMLIQAAIVRIMKTRKTLKHQHLVVEVL 164
+K+ + I ++ + E E T ++EDRKM +QAAIVRIMK RK L+H L+ EV+
Sbjct: 588 SSKRTKFKITTSMQKDTPQEMEQTRSAVDEDRKMYLQAAIVRIMKARKVLRHNALIQEVI 647
Query: 163 NQLSSRFKPRVPVIKKCIDILIEKEYLERTEGEKDTYSYLA 41
+Q +RF P + +IKKCI++LI+K+Y+ER++ D YSY+A
Sbjct: 648 SQSRARFNPSISMIKKCIEVLIDKQYIERSQASADEYSYVA 688
>AF126404-1|AAD23581.1| 745|Homo sapiens cullin 2 protein.
Length = 745
Score = 178 bits (434), Expect = 1e-44
Identities = 83/221 (37%), Positives = 135/221 (61%)
Frame = -2
Query: 703 TSFQLPTEXERSVHRFTTFYSSQHSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAV 524
++F +P E E+SV F FYS SGRKL WL+ + GE+ N Y +T+QMAV
Sbjct: 525 STFAIPQELEKSVQMFELFYSQHFSGRKLTWLHYLCTGEVKMNYLGKPYVAMVTTYQMAV 584
Query: 523 LLQYNDNTSWTVRQLEQHTGIKGDFLIQVLQILLKAKLLVCQEDEAELGENSVVDLYSGY 344
LL +N++ + + ++L+ T + L + ++ LL K++ ++ ++ S L +
Sbjct: 585 LLAFNNSETVSYKELQDSTQMNEKELTKTIKSLLDVKMINHDSEKEDIDAESSFSLNMNF 644
Query: 343 KNKKLRVNINIPLKTELKVEQEATHKHIEEDRKMLIQAAIVRIMKTRKTLKHQHLVVEVL 164
+K+ + I ++ + E E T ++EDRKM +QAAIVRIMK RK L+H L+ EV+
Sbjct: 645 SSKRTKFKITTSMQKDTPQEMEQTRSAVDEDRKMYLQAAIVRIMKARKVLRHNALIQEVI 704
Query: 163 NQLSSRFKPRVPVIKKCIDILIEKEYLERTEGEKDTYSYLA 41
+Q +RF P + +IKKCI++LI+K+Y+ER++ D YSY+A
Sbjct: 705 SQSRARFNPSISMIKKCIEVLIDKQYIERSQASADEYSYVA 745
>U58088-1|AAC50545.1| 651|Homo sapiens Hs-CUL-2 protein.
Length = 651
Score = 176 bits (429), Expect = 6e-44
Identities = 82/221 (37%), Positives = 134/221 (60%)
Frame = -2
Query: 703 TSFQLPTEXERSVHRFTTFYSSQHSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAV 524
++F +P E E+SV F FYS SGRKL WL+ + GE+ N Y +T+QMAV
Sbjct: 431 STFAIPQELEKSVQMFELFYSQHFSGRKLTWLHYLCTGEVKMNYLGKPYVAMVTTYQMAV 490
Query: 523 LLQYNDNTSWTVRQLEQHTGIKGDFLIQVLQILLKAKLLVCQEDEAELGENSVVDLYSGY 344
LL +N++ + + ++L+ T + L + ++ LL K++ ++ ++ S L +
Sbjct: 491 LLAFNNSETVSYKELQDSTQMNEKELTKTIKSLLDVKMINHDSEKEDIDAESSFSLNMNF 550
Query: 343 KNKKLRVNINIPLKTELKVEQEATHKHIEEDRKMLIQAAIVRIMKTRKTLKHQHLVVEVL 164
+K+ + I ++ + E E T ++EDRKM + AAIVRIMK RK L+H L+ EV+
Sbjct: 551 SSKRTKFKITTSMQKDTPQEMEQTRSAVDEDRKMYLHAAIVRIMKARKVLRHNALIQEVI 610
Query: 163 NQLSSRFKPRVPVIKKCIDILIEKEYLERTEGEKDTYSYLA 41
+Q +RF P + +IKKCI++LI+K+Y+ER++ D YSY+A
Sbjct: 611 SQSRARFNPSISMIKKCIEVLIDKQYIERSQASADEYSYVA 651
>U58091-1|AAC50548.1| 288|Homo sapiens Hs-CUL-4B protein.
Length = 288
Score = 131 bits (317), Expect = 2e-30
Identities = 80/219 (36%), Positives = 118/219 (53%), Gaps = 2/219 (0%)
Frame = -2
Query: 691 LPTEXERSVHRFTTFYSSQHSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAVLLQY 512
LP E + F TFY +HSGRKL W + L + + LQ S FQ VLL +
Sbjct: 72 LPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKEGKKELQVSLFQTLVLLMF 131
Query: 511 NDNTSWTVRQLEQHTGIKGDFLIQVLQILL--KAKLLVCQEDEAELGENSVVDLYSGYKN 338
N+ +++ +++Q TGI+ L + LQ L KA++L ++ + +K+
Sbjct: 132 NEGEEFSLEEIKQATGIEDGELRRTLQSLACGKARVLAKNPKGKDIEDGDKFICNDDFKH 191
Query: 337 KKLRVNINIPLKTELKVEQEATHKHIEEDRKMLIQAAIVRIMKTRKTLKHQHLVVEVLNQ 158
K R+ IN E EQ +T + + +DR+ I AAIVRIMK RKTL H LV EV NQ
Sbjct: 192 KLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQ 251
Query: 157 LSSRFKPRVPVIKKCIDILIEKEYLERTEGEKDTYSYLA 41
L KP +KK I+ LI+++Y+ER + + Y+Y+A
Sbjct: 252 LKFPVKP--ADLKKRIESLIDRDYMERDKENPNQYNYIA 288
>BX537787-1|CAD97843.1| 895|Homo sapiens hypothetical protein
protein.
Length = 895
Score = 131 bits (317), Expect = 2e-30
Identities = 80/219 (36%), Positives = 118/219 (53%), Gaps = 2/219 (0%)
Frame = -2
Query: 691 LPTEXERSVHRFTTFYSSQHSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAVLLQY 512
LP E + F TFY +HSGRKL W + L + + LQ S FQ VLL +
Sbjct: 679 LPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKEGKKELQVSLFQTLVLLMF 738
Query: 511 NDNTSWTVRQLEQHTGIKGDFLIQVLQILL--KAKLLVCQEDEAELGENSVVDLYSGYKN 338
N+ +++ +++Q TGI+ L + LQ L KA++L ++ + +K+
Sbjct: 739 NEGEEFSLEEIKQATGIEDGELRRTLQSLACGKARVLAKNPKGKDIEDGDKFICNDDFKH 798
Query: 337 KKLRVNINIPLKTELKVEQEATHKHIEEDRKMLIQAAIVRIMKTRKTLKHQHLVVEVLNQ 158
K R+ IN E EQ +T + + +DR+ I AAIVRIMK RKTL H LV EV NQ
Sbjct: 799 KLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQ 858
Query: 157 LSSRFKPRVPVIKKCIDILIEKEYLERTEGEKDTYSYLA 41
L KP +KK I+ LI+++Y+ER + + Y+Y+A
Sbjct: 859 LKFPVKP--ADLKKRIESLIDRDYMERDKENPNQYNYIA 895
>AL451005-1|CAI41370.1| 913|Homo sapiens cullin 4B protein.
Length = 913
Score = 131 bits (317), Expect = 2e-30
Identities = 80/219 (36%), Positives = 118/219 (53%), Gaps = 2/219 (0%)
Frame = -2
Query: 691 LPTEXERSVHRFTTFYSSQHSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAVLLQY 512
LP E + F TFY +HSGRKL W + L + + LQ S FQ VLL +
Sbjct: 697 LPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKEGKKELQVSLFQTLVLLMF 756
Query: 511 NDNTSWTVRQLEQHTGIKGDFLIQVLQILL--KAKLLVCQEDEAELGENSVVDLYSGYKN 338
N+ +++ +++Q TGI+ L + LQ L KA++L ++ + +K+
Sbjct: 757 NEGEEFSLEEIKQATGIEDGELRRTLQSLACGKARVLAKNPKGKDIEDGDKFICNDDFKH 816
Query: 337 KKLRVNINIPLKTELKVEQEATHKHIEEDRKMLIQAAIVRIMKTRKTLKHQHLVVEVLNQ 158
K R+ IN E EQ +T + + +DR+ I AAIVRIMK RKTL H LV EV NQ
Sbjct: 817 KLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQ 876
Query: 157 LSSRFKPRVPVIKKCIDILIEKEYLERTEGEKDTYSYLA 41
L KP +KK I+ LI+++Y+ER + + Y+Y+A
Sbjct: 877 LKFPVKP--ADLKKRIESLIDRDYMERDKENPNQYNYIA 913
>AF212995-1|AAK16812.1| 782|Homo sapiens cullin CUL4B protein.
Length = 782
Score = 131 bits (317), Expect = 2e-30
Identities = 80/219 (36%), Positives = 118/219 (53%), Gaps = 2/219 (0%)
Frame = -2
Query: 691 LPTEXERSVHRFTTFYSSQHSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAVLLQY 512
LP E + F TFY +HSGRKL W + L + + LQ S FQ VLL +
Sbjct: 566 LPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKEGKKELQVSLFQTLVLLMF 625
Query: 511 NDNTSWTVRQLEQHTGIKGDFLIQVLQILL--KAKLLVCQEDEAELGENSVVDLYSGYKN 338
N+ +++ +++Q TGI+ L + LQ L KA++L ++ + +K+
Sbjct: 626 NEGEEFSLEEIKQATGIEDGELRRTLQSLACGKARVLAKNPKGKDIEDGDKFICNDDFKH 685
Query: 337 KKLRVNINIPLKTELKVEQEATHKHIEEDRKMLIQAAIVRIMKTRKTLKHQHLVVEVLNQ 158
K R+ IN E EQ +T + + +DR+ I AAIVRIMK RKTL H LV EV NQ
Sbjct: 686 KLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQ 745
Query: 157 LSSRFKPRVPVIKKCIDILIEKEYLERTEGEKDTYSYLA 41
L KP +KK I+ LI+++Y+ER + + Y+Y+A
Sbjct: 746 LKFPVKP--ADLKKRIESLIDRDYMERDKENPNQYNYIA 782
>AC002476-3|AAB67315.1| 652|Homo sapiens WUGSC:H_DJ318C15.2 protein.
Length = 652
Score = 131 bits (317), Expect = 2e-30
Identities = 80/219 (36%), Positives = 118/219 (53%), Gaps = 2/219 (0%)
Frame = -2
Query: 691 LPTEXERSVHRFTTFYSSQHSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAVLLQY 512
LP E + F TFY +HSGRKL W + L + + LQ S FQ VLL +
Sbjct: 436 LPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKEGKKELQVSLFQTLVLLMF 495
Query: 511 NDNTSWTVRQLEQHTGIKGDFLIQVLQILL--KAKLLVCQEDEAELGENSVVDLYSGYKN 338
N+ +++ +++Q TGI+ L + LQ L KA++L ++ + +K+
Sbjct: 496 NEGEEFSLEEIKQATGIEDGELRRTLQSLACGKARVLAKNPKGKDIEDGDKFICNDDFKH 555
Query: 337 KKLRVNINIPLKTELKVEQEATHKHIEEDRKMLIQAAIVRIMKTRKTLKHQHLVVEVLNQ 158
K R+ IN E EQ +T + + +DR+ I AAIVRIMK RKTL H LV EV NQ
Sbjct: 556 KLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQ 615
Query: 157 LSSRFKPRVPVIKKCIDILIEKEYLERTEGEKDTYSYLA 41
L KP +KK I+ LI+++Y+ER + + Y+Y+A
Sbjct: 616 LKFPVKP--ADLKKRIESLIDRDYMERDKENPNQYNYIA 652
>AB014595-1|BAA31670.2| 781|Homo sapiens KIAA0695 protein protein.
Length = 781
Score = 131 bits (317), Expect = 2e-30
Identities = 80/219 (36%), Positives = 118/219 (53%), Gaps = 2/219 (0%)
Frame = -2
Query: 691 LPTEXERSVHRFTTFYSSQHSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAVLLQY 512
LP E + F TFY +HSGRKL W + L + + LQ S FQ VLL +
Sbjct: 565 LPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKEGKKELQVSLFQTLVLLMF 624
Query: 511 NDNTSWTVRQLEQHTGIKGDFLIQVLQILL--KAKLLVCQEDEAELGENSVVDLYSGYKN 338
N+ +++ +++Q TGI+ L + LQ L KA++L ++ + +K+
Sbjct: 625 NEGEEFSLEEIKQATGIEDGELRRTLQSLACGKARVLAKNPKGKDIEDGDKFICNDDFKH 684
Query: 337 KKLRVNINIPLKTELKVEQEATHKHIEEDRKMLIQAAIVRIMKTRKTLKHQHLVVEVLNQ 158
K R+ IN E EQ +T + + +DR+ I AAIVRIMK RKTL H LV EV NQ
Sbjct: 685 KLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQ 744
Query: 157 LSSRFKPRVPVIKKCIDILIEKEYLERTEGEKDTYSYLA 41
L KP +KK I+ LI+++Y+ER + + Y+Y+A
Sbjct: 745 LKFPVKP--ADLKKRIESLIDRDYMERDKENPNQYNYIA 781
>BC036216-1|AAH36216.1| 913|Homo sapiens cullin 4B protein.
Length = 913
Score = 131 bits (316), Expect = 3e-30
Identities = 80/219 (36%), Positives = 118/219 (53%), Gaps = 2/219 (0%)
Frame = -2
Query: 691 LPTEXERSVHRFTTFYSSQHSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAVLLQY 512
LP E + F TFY +HSGRKL W + L + + LQ S FQ VLL +
Sbjct: 697 LPPEMVKLQEIFKTFYLGKHSGRKLQWQSTIGHCVLKAEFKEGKKELQVSLFQTLVLLMF 756
Query: 511 NDNTSWTVRQLEQHTGIKGDFLIQVLQILL--KAKLLVCQEDEAELGENSVVDLYSGYKN 338
N+ +++ +++Q TGI+ L + LQ L KA++L ++ + +K+
Sbjct: 757 NEGEEFSLEEIKQATGIEDGELRRTLQSLACGKARVLAKNPKGKDIEDGDKFICNDDFKH 816
Query: 337 KKLRVNINIPLKTELKVEQEATHKHIEEDRKMLIQAAIVRIMKTRKTLKHQHLVVEVLNQ 158
K R+ IN E EQ +T + + +DR+ I AAIVRIMK RKTL H LV EV NQ
Sbjct: 817 KLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQ 876
Query: 157 LSSRFKPRVPVIKKCIDILIEKEYLERTEGEKDTYSYLA 41
L KP +KK I+ LI+++Y+ER + + Y+Y+A
Sbjct: 877 LKFPVKP--ADLKKRIESLIDRDYMERDKENPNQYNYIA 913
>AY365125-1|AAR13073.1| 895|Homo sapiens cullin 4B protein.
Length = 895
Score = 131 bits (316), Expect = 3e-30
Identities = 80/219 (36%), Positives = 118/219 (53%), Gaps = 2/219 (0%)
Frame = -2
Query: 691 LPTEXERSVHRFTTFYSSQHSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAVLLQY 512
LP E + F TFY +HSGRKL W + L + + LQ S FQ VLL +
Sbjct: 679 LPPEMVKLQEIFKTFYLGKHSGRKLQWQSTIGHCVLKAEFKEGKKELQVSLFQTLVLLMF 738
Query: 511 NDNTSWTVRQLEQHTGIKGDFLIQVLQILL--KAKLLVCQEDEAELGENSVVDLYSGYKN 338
N+ +++ +++Q TGI+ L + LQ L KA++L ++ + +K+
Sbjct: 739 NEGEEFSLEEIKQATGIEDGELRRTLQSLACGKARVLAKNPKGKDIEDGDKFICNDDFKH 798
Query: 337 KKLRVNINIPLKTELKVEQEATHKHIEEDRKMLIQAAIVRIMKTRKTLKHQHLVVEVLNQ 158
K R+ IN E EQ +T + + +DR+ I AAIVRIMK RKTL H LV EV NQ
Sbjct: 799 KLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQ 858
Query: 157 LSSRFKPRVPVIKKCIDILIEKEYLERTEGEKDTYSYLA 41
L KP +KK I+ LI+++Y+ER + + Y+Y+A
Sbjct: 859 LKFPVKP--ADLKKRIESLIDRDYMERDKENPNQYNYIA 895
>U58090-1|AAC50547.1| 421|Homo sapiens Hs-CUL-4A protein.
Length = 421
Score = 122 bits (294), Expect = 1e-27
Identities = 74/208 (35%), Positives = 110/208 (52%), Gaps = 2/208 (0%)
Frame = -2
Query: 658 FTTFYSSQHSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAVLLQYNDNTSWTVRQL 479
F FY +HSGRKL W + L + + Q S FQ VLL +N+ ++ ++
Sbjct: 216 FKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEEI 275
Query: 478 EQHTGIKGDFLIQVLQILL--KAKLLVCQEDEAELGENSVVDLYSGYKNKKLRVNINIPL 305
+ TGI+ L + LQ L KA++L+ E+ + +K+K R+ IN
Sbjct: 276 KMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQ 335
Query: 304 KTELKVEQEATHKHIEEDRKMLIQAAIVRIMKTRKTLKHQHLVVEVLNQLSSRFKPRVPV 125
E EQ +T + + +DR+ I AAIVRIMK RKTL H LV E+ NQL KP
Sbjct: 336 MKETVEEQVSTTERVFQDRQYQIDAAIVRIMKMRKTLGHNLLVSELYNQLKFPVKP--GD 393
Query: 124 IKKCIDILIEKEYLERTEGEKDTYSYLA 41
+KK I+ LI+++Y+ER + + Y Y+A
Sbjct: 394 LKKRIESLIDRDYMERDKDNPNQYHYVA 421
>BC008308-1|AAH08308.2| 759|Homo sapiens cullin 4A protein.
Length = 759
Score = 122 bits (294), Expect = 1e-27
Identities = 74/208 (35%), Positives = 110/208 (52%), Gaps = 2/208 (0%)
Frame = -2
Query: 658 FTTFYSSQHSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAVLLQYNDNTSWTVRQL 479
F FY +HSGRKL W + L + + Q S FQ VLL +N+ ++ ++
Sbjct: 554 FKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEEI 613
Query: 478 EQHTGIKGDFLIQVLQILL--KAKLLVCQEDEAELGENSVVDLYSGYKNKKLRVNINIPL 305
+ TGI+ L + LQ L KA++L+ E+ + +K+K R+ IN
Sbjct: 614 KMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQ 673
Query: 304 KTELKVEQEATHKHIEEDRKMLIQAAIVRIMKTRKTLKHQHLVVEVLNQLSSRFKPRVPV 125
E EQ +T + + +DR+ I AAIVRIMK RKTL H LV E+ NQL KP
Sbjct: 674 MKETVEEQVSTTERVFQDRQYQIDAAIVRIMKMRKTLGHNLLVSELYNQLKFPVKP--GD 731
Query: 124 IKKCIDILIEKEYLERTEGEKDTYSYLA 41
+KK I+ LI+++Y+ER + + Y Y+A
Sbjct: 732 LKKRIESLIDRDYMERDKDNPNQYHYVA 759
>AY365124-1|AAR13072.1| 759|Homo sapiens cullin 4A protein.
Length = 759
Score = 122 bits (294), Expect = 1e-27
Identities = 74/208 (35%), Positives = 110/208 (52%), Gaps = 2/208 (0%)
Frame = -2
Query: 658 FTTFYSSQHSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAVLLQYNDNTSWTVRQL 479
F FY +HSGRKL W + L + + Q S FQ VLL +N+ ++ ++
Sbjct: 554 FKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEEI 613
Query: 478 EQHTGIKGDFLIQVLQILL--KAKLLVCQEDEAELGENSVVDLYSGYKNKKLRVNINIPL 305
+ TGI+ L + LQ L KA++L+ E+ + +K+K R+ IN
Sbjct: 614 KMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQ 673
Query: 304 KTELKVEQEATHKHIEEDRKMLIQAAIVRIMKTRKTLKHQHLVVEVLNQLSSRFKPRVPV 125
E EQ +T + + +DR+ I AAIVRIMK RKTL H LV E+ NQL KP
Sbjct: 674 MKETVEEQVSTTERVFQDRQYQIDAAIVRIMKMRKTLGHNLLVSELYNQLKFPVKP--GD 731
Query: 124 IKKCIDILIEKEYLERTEGEKDTYSYLA 41
+KK I+ LI+++Y+ER + + Y Y+A
Sbjct: 732 LKKRIESLIDRDYMERDKDNPNQYHYVA 759
>AL136221-5|CAI13795.1| 659|Homo sapiens cullin 4A protein.
Length = 659
Score = 122 bits (294), Expect = 1e-27
Identities = 74/208 (35%), Positives = 110/208 (52%), Gaps = 2/208 (0%)
Frame = -2
Query: 658 FTTFYSSQHSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAVLLQYNDNTSWTVRQL 479
F FY +HSGRKL W + L + + Q S FQ VLL +N+ ++ ++
Sbjct: 454 FKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEEI 513
Query: 478 EQHTGIKGDFLIQVLQILL--KAKLLVCQEDEAELGENSVVDLYSGYKNKKLRVNINIPL 305
+ TGI+ L + LQ L KA++L+ E+ + +K+K R+ IN
Sbjct: 514 KMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQ 573
Query: 304 KTELKVEQEATHKHIEEDRKMLIQAAIVRIMKTRKTLKHQHLVVEVLNQLSSRFKPRVPV 125
E EQ +T + + +DR+ I AAIVRIMK RKTL H LV E+ NQL KP
Sbjct: 574 MKETVEEQVSTTERVFQDRQYQIDAAIVRIMKMRKTLGHNLLVSELYNQLKFPVKP--GD 631
Query: 124 IKKCIDILIEKEYLERTEGEKDTYSYLA 41
+KK I+ LI+++Y+ER + + Y Y+A
Sbjct: 632 LKKRIESLIDRDYMERDKDNPNQYHYVA 659
>AL136221-4|CAM18410.1| 759|Homo sapiens cullin 4A protein.
Length = 759
Score = 122 bits (294), Expect = 1e-27
Identities = 74/208 (35%), Positives = 110/208 (52%), Gaps = 2/208 (0%)
Frame = -2
Query: 658 FTTFYSSQHSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAVLLQYNDNTSWTVRQL 479
F FY +HSGRKL W + L + + Q S FQ VLL +N+ ++ ++
Sbjct: 554 FKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEEI 613
Query: 478 EQHTGIKGDFLIQVLQILL--KAKLLVCQEDEAELGENSVVDLYSGYKNKKLRVNINIPL 305
+ TGI+ L + LQ L KA++L+ E+ + +K+K R+ IN
Sbjct: 614 KMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQ 673
Query: 304 KTELKVEQEATHKHIEEDRKMLIQAAIVRIMKTRKTLKHQHLVVEVLNQLSSRFKPRVPV 125
E EQ +T + + +DR+ I AAIVRIMK RKTL H LV E+ NQL KP
Sbjct: 674 MKETVEEQVSTTERVFQDRQYQIDAAIVRIMKMRKTLGHNLLVSELYNQLKFPVKP--GD 731
Query: 124 IKKCIDILIEKEYLERTEGEKDTYSYLA 41
+KK I+ LI+++Y+ER + + Y Y+A
Sbjct: 732 LKKRIESLIDRDYMERDKDNPNQYHYVA 759
>AF077188-1|AAD45191.1| 659|Homo sapiens cullin 4A protein.
Length = 659
Score = 122 bits (294), Expect = 1e-27
Identities = 74/208 (35%), Positives = 110/208 (52%), Gaps = 2/208 (0%)
Frame = -2
Query: 658 FTTFYSSQHSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAVLLQYNDNTSWTVRQL 479
F FY +HSGRKL W + L + + Q S FQ VLL +N+ ++ ++
Sbjct: 454 FKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEEI 513
Query: 478 EQHTGIKGDFLIQVLQILL--KAKLLVCQEDEAELGENSVVDLYSGYKNKKLRVNINIPL 305
+ TGI+ L + LQ L KA++L+ E+ + +K+K R+ IN
Sbjct: 514 KMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQ 573
Query: 304 KTELKVEQEATHKHIEEDRKMLIQAAIVRIMKTRKTLKHQHLVVEVLNQLSSRFKPRVPV 125
E EQ +T + + +DR+ I AAIVRIMK RKTL H LV E+ NQL KP
Sbjct: 574 MKETVEEQVSTTERVFQDRQYQIDAAIVRIMKMRKTLGHNLLVSELYNQLKFPVKP--GD 631
Query: 124 IKKCIDILIEKEYLERTEGEKDTYSYLA 41
+KK I+ LI+++Y+ER + + Y Y+A
Sbjct: 632 LKKRIESLIDRDYMERDKDNPNQYHYVA 659
>AB178950-1|BAD93235.1| 759|Homo sapiens cullin-4A protein.
Length = 759
Score = 122 bits (294), Expect = 1e-27
Identities = 74/208 (35%), Positives = 110/208 (52%), Gaps = 2/208 (0%)
Frame = -2
Query: 658 FTTFYSSQHSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAVLLQYNDNTSWTVRQL 479
F FY +HSGRKL W + L + + Q S FQ VLL +N+ ++ ++
Sbjct: 554 FKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEEI 613
Query: 478 EQHTGIKGDFLIQVLQILL--KAKLLVCQEDEAELGENSVVDLYSGYKNKKLRVNINIPL 305
+ TGI+ L + LQ L KA++L+ E+ + +K+K R+ IN
Sbjct: 614 KMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQ 673
Query: 304 KTELKVEQEATHKHIEEDRKMLIQAAIVRIMKTRKTLKHQHLVVEVLNQLSSRFKPRVPV 125
E EQ +T + + +DR+ I AAIVRIMK RKTL H LV E+ NQL KP
Sbjct: 674 MKETVEEQVSTTERVFQDRQYQIDAAIVRIMKMRKTLGHNLLVSELYNQLKFPVKP--GD 731
Query: 124 IKKCIDILIEKEYLERTEGEKDTYSYLA 41
+KK I+ LI+++Y+ER + + Y Y+A
Sbjct: 732 LKKRIESLIDRDYMERDKDNPNQYHYVA 759
>AB012193-1|BAA33146.1| 524|Homo sapiens cullin-4A protein.
Length = 524
Score = 122 bits (294), Expect = 1e-27
Identities = 74/208 (35%), Positives = 110/208 (52%), Gaps = 2/208 (0%)
Frame = -2
Query: 658 FTTFYSSQHSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAVLLQYNDNTSWTVRQL 479
F FY +HSGRKL W + L + + Q S FQ VLL +N+ ++ ++
Sbjct: 319 FKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEEI 378
Query: 478 EQHTGIKGDFLIQVLQILL--KAKLLVCQEDEAELGENSVVDLYSGYKNKKLRVNINIPL 305
+ TGI+ L + LQ L KA++L+ E+ + +K+K R+ IN
Sbjct: 379 KMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQ 438
Query: 304 KTELKVEQEATHKHIEEDRKMLIQAAIVRIMKTRKTLKHQHLVVEVLNQLSSRFKPRVPV 125
E EQ +T + + +DR+ I AAIVRIMK RKTL H LV E+ NQL KP
Sbjct: 439 MKETVEEQVSTTERVFQDRQYQIDAAIVRIMKMRKTLGHNLLVSELYNQLKFPVKP--GD 496
Query: 124 IKKCIDILIEKEYLERTEGEKDTYSYLA 41
+KK I+ LI+++Y+ER + + Y Y+A
Sbjct: 497 LKKRIESLIDRDYMERDKDNPNQYHYVA 524
>U58089-1|AAC50546.1| 577|Homo sapiens Hs-CUL-3 protein.
Length = 577
Score = 117 bits (282), Expect = 4e-26
Identities = 80/245 (32%), Positives = 126/245 (51%), Gaps = 28/245 (11%)
Frame = -2
Query: 691 LPTEXERSVHRFTTFYSSQHSGRKLNWLYNMSKGEL----------------------LT 578
+P + F FY ++HSGR+L ++M +L +T
Sbjct: 333 IPPAPRHAFEIFRRFYLAKHSGRQLTLQHHMGSADLNATFYGPVKKEDGSEVGVGGAQVT 392
Query: 577 NCFKNRYTLQASTFQMAVLLQYNDNTSWTVRQLEQHTGIKGDFLIQVLQILLKAK----L 410
++ LQ STFQM +L+ +N+ +T +++Q T I L++ LQ L K +
Sbjct: 393 GSNTRKHILQVSTFQMTILMLFNNREKYTFEEIQQETDIPERELVRALQSLACGKPTQRV 452
Query: 409 LVCQEDEAELGENSVVDLYSGYKNKKLRVNIN-IPLKT-ELKVEQEATHKHIEEDRKMLI 236
L + E+ + + + +K RV I + K E E++ T + +++DRK I
Sbjct: 453 LTKEPKSKEIENGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEI 512
Query: 235 QAAIVRIMKTRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDILIEKEYLERTEGEKDT 56
+AAIVRIMK+RK ++H LV EV QL +RF P VIKK I+ LIE+EYL RT ++
Sbjct: 513 EAAIVRIMKSRKKMQHNVLVAEVTQQLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKV 572
Query: 55 YSYLA 41
Y+Y+A
Sbjct: 573 YTYVA 577
>BC092409-1|AAH92409.1| 768|Homo sapiens cullin 3 protein.
Length = 768
Score = 117 bits (282), Expect = 4e-26
Identities = 80/245 (32%), Positives = 126/245 (51%), Gaps = 28/245 (11%)
Frame = -2
Query: 691 LPTEXERSVHRFTTFYSSQHSGRKLNWLYNMSKGEL----------------------LT 578
+P + F FY ++HSGR+L ++M +L +T
Sbjct: 524 IPPAPRHAFEIFRRFYLAKHSGRQLTLQHHMGSADLNATFYGPVKKEDGSEVGVGGAQVT 583
Query: 577 NCFKNRYTLQASTFQMAVLLQYNDNTSWTVRQLEQHTGIKGDFLIQVLQILLKAK----L 410
++ LQ STFQM +L+ +N+ +T +++Q T I L++ LQ L K +
Sbjct: 584 GSNTRKHILQVSTFQMTILMLFNNREKYTFEEIQQETDIPERELVRALQSLACGKPTQRV 643
Query: 409 LVCQEDEAELGENSVVDLYSGYKNKKLRVNIN-IPLKT-ELKVEQEATHKHIEEDRKMLI 236
L + E+ + + + +K RV I + K E E++ T + +++DRK I
Sbjct: 644 LTKEPKSKEIENGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEI 703
Query: 235 QAAIVRIMKTRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDILIEKEYLERTEGEKDT 56
+AAIVRIMK+RK ++H LV EV QL +RF P VIKK I+ LIE+EYL RT ++
Sbjct: 704 EAAIVRIMKSRKKMQHNVLVAEVTQQLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKV 763
Query: 55 YSYLA 41
Y+Y+A
Sbjct: 764 YTYVA 768
>BC039598-1|AAH39598.1| 768|Homo sapiens cullin 3 protein.
Length = 768
Score = 117 bits (282), Expect = 4e-26
Identities = 80/245 (32%), Positives = 126/245 (51%), Gaps = 28/245 (11%)
Frame = -2
Query: 691 LPTEXERSVHRFTTFYSSQHSGRKLNWLYNMSKGEL----------------------LT 578
+P + F FY ++HSGR+L ++M +L +T
Sbjct: 524 IPPAPRHAFEIFRRFYLAKHSGRQLTLQHHMGSADLNATFYGPVKKEDGSEVGVGGAQVT 583
Query: 577 NCFKNRYTLQASTFQMAVLLQYNDNTSWTVRQLEQHTGIKGDFLIQVLQILLKAK----L 410
++ LQ STFQM +L+ +N+ +T +++Q T I L++ LQ L K +
Sbjct: 584 GSNTRKHILQVSTFQMTILMLFNNREKYTFEEIQQETDIPERELVRALQSLACGKPTQRV 643
Query: 409 LVCQEDEAELGENSVVDLYSGYKNKKLRVNIN-IPLKT-ELKVEQEATHKHIEEDRKMLI 236
L + E+ + + + +K RV I + K E E++ T + +++DRK I
Sbjct: 644 LTKEPKSKEIENGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEI 703
Query: 235 QAAIVRIMKTRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDILIEKEYLERTEGEKDT 56
+AAIVRIMK+RK ++H LV EV QL +RF P VIKK I+ LIE+EYL RT ++
Sbjct: 704 EAAIVRIMKSRKKMQHNVLVAEVTQQLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKV 763
Query: 55 YSYLA 41
Y+Y+A
Sbjct: 764 YTYVA 768
>AF064087-1|AAC36304.1| 768|Homo sapiens cullin 3 protein.
Length = 768
Score = 117 bits (282), Expect = 4e-26
Identities = 80/245 (32%), Positives = 126/245 (51%), Gaps = 28/245 (11%)
Frame = -2
Query: 691 LPTEXERSVHRFTTFYSSQHSGRKLNWLYNMSKGEL----------------------LT 578
+P + F FY ++HSGR+L ++M +L +T
Sbjct: 524 IPPAPRHAFEIFRRFYLAKHSGRQLTLQHHMGSADLNATFYGPVKKEDGSEVGVGGAQVT 583
Query: 577 NCFKNRYTLQASTFQMAVLLQYNDNTSWTVRQLEQHTGIKGDFLIQVLQILLKAK----L 410
++ LQ STFQM +L+ +N+ +T +++Q T I L++ LQ L K +
Sbjct: 584 GSNTRKHILQVSTFQMTILMLFNNREKYTFEEIQQETDIPERELVRALQSLACGKPTQRV 643
Query: 409 LVCQEDEAELGENSVVDLYSGYKNKKLRVNIN-IPLKT-ELKVEQEATHKHIEEDRKMLI 236
L + E+ + + + +K RV I + K E E++ T + +++DRK I
Sbjct: 644 LTKEPKSKEIENGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEI 703
Query: 235 QAAIVRIMKTRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDILIEKEYLERTEGEKDT 56
+AAIVRIMK+RK ++H LV EV QL +RF P VIKK I+ LIE+EYL RT ++
Sbjct: 704 EAAIVRIMKSRKKMQHNVLVAEVTQQLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKV 763
Query: 55 YSYLA 41
Y+Y+A
Sbjct: 764 YTYVA 768
>AF062537-1|AAC36682.1| 768|Homo sapiens cullin 3 protein.
Length = 768
Score = 117 bits (282), Expect = 4e-26
Identities = 80/245 (32%), Positives = 126/245 (51%), Gaps = 28/245 (11%)
Frame = -2
Query: 691 LPTEXERSVHRFTTFYSSQHSGRKLNWLYNMSKGEL----------------------LT 578
+P + F FY ++HSGR+L ++M +L +T
Sbjct: 524 IPPAPRHAFEIFRRFYLAKHSGRQLTLQHHMGSADLNATFYGPVKKEDGSEVGVGGAQVT 583
Query: 577 NCFKNRYTLQASTFQMAVLLQYNDNTSWTVRQLEQHTGIKGDFLIQVLQILLKAK----L 410
++ LQ STFQM +L+ +N+ +T +++Q T I L++ LQ L K +
Sbjct: 584 GSNTRKHILQVSTFQMTILMLFNNREKYTFEEIQQETDIPERELVRALQSLACGKPTQRV 643
Query: 409 LVCQEDEAELGENSVVDLYSGYKNKKLRVNIN-IPLKT-ELKVEQEATHKHIEEDRKMLI 236
L + E+ + + + +K RV I + K E E++ T + +++DRK I
Sbjct: 644 LTKEPKSKEIENGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEI 703
Query: 235 QAAIVRIMKTRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDILIEKEYLERTEGEKDT 56
+AAIVRIMK+RK ++H LV EV QL +RF P VIKK I+ LIE+EYL RT ++
Sbjct: 704 EAAIVRIMKSRKKMQHNVLVAEVTQQLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKV 763
Query: 55 YSYLA 41
Y+Y+A
Sbjct: 764 YTYVA 768
>AF052147-1|AAC28621.1| 343|Homo sapiens cul-3 protein.
Length = 343
Score = 117 bits (282), Expect = 4e-26
Identities = 80/245 (32%), Positives = 126/245 (51%), Gaps = 28/245 (11%)
Frame = -2
Query: 691 LPTEXERSVHRFTTFYSSQHSGRKLNWLYNMSKGEL----------------------LT 578
+P + F FY ++HSGR+L ++M +L +T
Sbjct: 99 IPPAPRHAFEIFRRFYLAKHSGRQLTLQHHMGSADLNATFYGPVKKEDGSEVGVGGAQVT 158
Query: 577 NCFKNRYTLQASTFQMAVLLQYNDNTSWTVRQLEQHTGIKGDFLIQVLQILLKAK----L 410
++ LQ STFQM +L+ +N+ +T +++Q T I L++ LQ L K +
Sbjct: 159 GSNTRKHILQVSTFQMTILMLFNNREKYTFEEIQQETDIPERELVRALQSLACGKPTQRV 218
Query: 409 LVCQEDEAELGENSVVDLYSGYKNKKLRVNIN-IPLKT-ELKVEQEATHKHIEEDRKMLI 236
L + E+ + + + +K RV I + K E E++ T + +++DRK I
Sbjct: 219 LTKEPKSKEIENGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEI 278
Query: 235 QAAIVRIMKTRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDILIEKEYLERTEGEKDT 56
+AAIVRIMK+RK ++H LV EV QL +RF P VIKK I+ LIE+EYL RT ++
Sbjct: 279 EAAIVRIMKSRKKMQHNVLVAEVTQQLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKV 338
Query: 55 YSYLA 41
Y+Y+A
Sbjct: 339 YTYVA 343
>AC073052-1|AAX93287.1| 746|Homo sapiens unknown protein.
Length = 746
Score = 117 bits (282), Expect = 4e-26
Identities = 80/245 (32%), Positives = 126/245 (51%), Gaps = 28/245 (11%)
Frame = -2
Query: 691 LPTEXERSVHRFTTFYSSQHSGRKLNWLYNMSKGEL----------------------LT 578
+P + F FY ++HSGR+L ++M +L +T
Sbjct: 502 IPPAPRHAFEIFRRFYLAKHSGRQLTLQHHMGSADLNATFYGPVKKEDGSEVGVGGAQVT 561
Query: 577 NCFKNRYTLQASTFQMAVLLQYNDNTSWTVRQLEQHTGIKGDFLIQVLQILLKAK----L 410
++ LQ STFQM +L+ +N+ +T +++Q T I L++ LQ L K +
Sbjct: 562 GSNTRKHILQVSTFQMTILMLFNNREKYTFEEIQQETDIPERELVRALQSLACGKPTQRV 621
Query: 409 LVCQEDEAELGENSVVDLYSGYKNKKLRVNIN-IPLKT-ELKVEQEATHKHIEEDRKMLI 236
L + E+ + + + +K RV I + K E E++ T + +++DRK I
Sbjct: 622 LTKEPKSKEIENGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEI 681
Query: 235 QAAIVRIMKTRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDILIEKEYLERTEGEKDT 56
+AAIVRIMK+RK ++H LV EV QL +RF P VIKK I+ LIE+EYL RT ++
Sbjct: 682 EAAIVRIMKSRKKMQHNVLVAEVTQQLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKV 741
Query: 55 YSYLA 41
Y+Y+A
Sbjct: 742 YTYVA 746
>AB014517-1|BAA31592.2| 786|Homo sapiens KIAA0617 protein protein.
Length = 786
Score = 117 bits (282), Expect = 4e-26
Identities = 80/245 (32%), Positives = 126/245 (51%), Gaps = 28/245 (11%)
Frame = -2
Query: 691 LPTEXERSVHRFTTFYSSQHSGRKLNWLYNMSKGEL----------------------LT 578
+P + F FY ++HSGR+L ++M +L +T
Sbjct: 542 IPPAPRHAFEIFRRFYLAKHSGRQLTLQHHMGSADLNATFYGPVKKEDGSEVGVGGAQVT 601
Query: 577 NCFKNRYTLQASTFQMAVLLQYNDNTSWTVRQLEQHTGIKGDFLIQVLQILLKAK----L 410
++ LQ STFQM +L+ +N+ +T +++Q T I L++ LQ L K +
Sbjct: 602 GSNTRKHILQVSTFQMTILMLFNNREKYTFEEIQQETDIPERELVRALQSLACGKPTQRV 661
Query: 409 LVCQEDEAELGENSVVDLYSGYKNKKLRVNIN-IPLKT-ELKVEQEATHKHIEEDRKMLI 236
L + E+ + + + +K RV I + K E E++ T + +++DRK I
Sbjct: 662 LTKEPKSKEIENGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEI 721
Query: 235 QAAIVRIMKTRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDILIEKEYLERTEGEKDT 56
+AAIVRIMK+RK ++H LV EV QL +RF P VIKK I+ LIE+EYL RT ++
Sbjct: 722 EAAIVRIMKSRKKMQHNVLVAEVTQQLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKV 781
Query: 55 YSYLA 41
Y+Y+A
Sbjct: 782 YTYVA 786
>BC031844-1|AAH31844.1| 373|Homo sapiens CUL3 protein protein.
Length = 373
Score = 117 bits (281), Expect = 5e-26
Identities = 80/245 (32%), Positives = 126/245 (51%), Gaps = 28/245 (11%)
Frame = -2
Query: 691 LPTEXERSVHRFTTFYSSQHSGRKLNWLYNMSKGEL----------------------LT 578
+P + F FY ++HSGR+L ++M +L +T
Sbjct: 129 IPPAPRHAFEIFRRFYLAKHSGRQLTLQHHMGSADLNATFYGPVKKEDGSEVGVGGAQVT 188
Query: 577 NCFKNRYTLQASTFQMAVLLQYNDNTSWTVRQLEQHTGIKGDFLIQVLQILLKAK----L 410
++ LQ STFQM +L+ +N+ +T +++Q T I L++ LQ L K +
Sbjct: 189 GSNTRKHILQVSTFQMTILMLFNNRGKYTFEEIQQETDIPERELVRALQSLACGKPTQRV 248
Query: 409 LVCQEDEAELGENSVVDLYSGYKNKKLRVNIN-IPLKT-ELKVEQEATHKHIEEDRKMLI 236
L + E+ + + + +K RV I + K E E++ T + +++DRK I
Sbjct: 249 LTKEPKSKEIENGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEI 308
Query: 235 QAAIVRIMKTRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDILIEKEYLERTEGEKDT 56
+AAIVRIMK+RK ++H LV EV QL +RF P VIKK I+ LIE+EYL RT ++
Sbjct: 309 EAAIVRIMKSRKKMQHNVLVAEVTQQLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKV 368
Query: 55 YSYLA 41
Y+Y+A
Sbjct: 369 YTYVA 373
>AY337761-1|AAQ01660.1| 744|Homo sapiens cullin 3 isoform protein.
Length = 744
Score = 116 bits (280), Expect = 6e-26
Identities = 80/245 (32%), Positives = 126/245 (51%), Gaps = 28/245 (11%)
Frame = -2
Query: 691 LPTEXERSVHRFTTFYSSQHSGRKLNWLYNMSKGEL----------------------LT 578
+P + F FY ++HSGR+L ++M +L +T
Sbjct: 500 IPPAPRHAFEIFRRFYLAKHSGRQLTLQHHMGSADLNATFYGPVKKEDGSEVGVGGAQVT 559
Query: 577 NCFKNRYTLQASTFQMAVLLQYNDNTSWTVRQLEQHTGIKGDFLIQVLQILLKAK----L 410
++ LQ STFQM +L+ +N+ +T +++Q T I L++ LQ L K +
Sbjct: 560 GSNTRKHILQVSTFQMTILMLFNNREKYTFEEIQQETDIPERELVRALQSLACGKPTQRV 619
Query: 409 LVCQEDEAELGENSVVDLYSGYKNKKLRVNIN-IPLKT-ELKVEQEATHKHIEEDRKMLI 236
L + E+ + + + +K RV I + K E E++ T + +++DRK I
Sbjct: 620 LTKEPKSKEIENGHIFTVNDQFISKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEI 679
Query: 235 QAAIVRIMKTRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDILIEKEYLERTEGEKDT 56
+AAIVRIMK+RK ++H LV EV QL +RF P VIKK I+ LIE+EYL RT ++
Sbjct: 680 EAAIVRIMKSRKKMQHNVLVAEVTQQLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKV 739
Query: 55 YSYLA 41
Y+Y+A
Sbjct: 740 YTYVA 744
>BC063306-1|AAH63306.1| 780|Homo sapiens cullin 5 protein.
Length = 780
Score = 94.3 bits (224), Expect = 4e-19
Identities = 74/234 (31%), Positives = 117/234 (50%), Gaps = 17/234 (7%)
Frame = -2
Query: 691 LPTEXERSVHRFTTFYSSQHSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAVLLQY 512
LPTE E + FY HSGRKL+W + MS G + +Y L+ +TFQ+AVL +
Sbjct: 547 LPTELEDLIPEVEEFYKKNHSGRKLHWHHLMSNGIITFKNEVGQYDLEVTTFQLAVLFAW 606
Query: 511 NDNTSWTV--RQLEQHTGIKGDFLIQVL-----------QILLKAKLLVCQEDEAELGEN 371
N + L+ T + L + L Q+LL + +D E
Sbjct: 607 NQRPREKISFENLKLATELPDAELRRTLWSLVAFPKLKRQVLLYEPQVNSPKDFTEGTLF 666
Query: 370 SVVDLYSGYKNKKL--RVNINIPLKTELKVE--QEATHKHIEEDRKMLIQAAIVRIMKTR 203
SV +S KN K+ R IN+ + +L E +E ++ I + R + Q AI++IMK R
Sbjct: 667 SVNQEFSLIKNAKVQKRGKINLIGRLQLTTERMREEENEGIVQLRILRTQEAIIQIMKMR 726
Query: 202 KTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDILIEKEYLERTEGEKDTYSYLA 41
K + + L E++ L + F P+ +IK+ I+ LIE +Y+ R E + +T+ Y+A
Sbjct: 727 KKISNAQLQTELVEILKNMFLPQKKMIKEQIEWLIEHKYIRRDESDINTFIYMA 780
>AF327710-1|AAK07472.1| 780|Homo sapiens cullin 5 protein.
Length = 780
Score = 94.3 bits (224), Expect = 4e-19
Identities = 74/234 (31%), Positives = 117/234 (50%), Gaps = 17/234 (7%)
Frame = -2
Query: 691 LPTEXERSVHRFTTFYSSQHSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAVLLQY 512
LPTE E + FY HSGRKL+W + MS G + +Y L+ +TFQ+AVL +
Sbjct: 547 LPTELEDLIPEVEEFYKKNHSGRKLHWHHLMSNGIITFKNEVGQYDLEVTTFQLAVLFAW 606
Query: 511 NDNTSWTV--RQLEQHTGIKGDFLIQVL-----------QILLKAKLLVCQEDEAELGEN 371
N + L+ T + L + L Q+LL + +D E
Sbjct: 607 NQRPREKISFENLKLATELPDAELRRTLWSLVAFPKLKRQVLLYEPQVNSPKDFTEGTLF 666
Query: 370 SVVDLYSGYKNKKL--RVNINIPLKTELKVE--QEATHKHIEEDRKMLIQAAIVRIMKTR 203
SV +S KN K+ R IN+ + +L E +E ++ I + R + Q AI++IMK R
Sbjct: 667 SVNQEFSLIKNAKVQKRGKINLIGRLQLTTERMREEENEGIVQLRILRTQEAIIQIMKMR 726
Query: 202 KTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDILIEKEYLERTEGEKDTYSYLA 41
K + + L E++ L + F P+ +IK+ I+ LIE +Y+ R E + +T+ Y+A
Sbjct: 727 KKISNAQLQTELVEILKNMFLPQKKMIKEQIEWLIEHKYIRRDESDINTFIYMA 780
>AF017061-1|AAB70253.1| 781|Homo sapiens vasopressin-activated
calcium mobilizing putative receptor protein protein.
Length = 781
Score = 94.3 bits (224), Expect = 4e-19
Identities = 74/234 (31%), Positives = 117/234 (50%), Gaps = 17/234 (7%)
Frame = -2
Query: 691 LPTEXERSVHRFTTFYSSQHSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAVLLQY 512
LPTE E + FY HSGRKL+W + MS G + +Y L+ +TFQ+AVL +
Sbjct: 548 LPTELEDLIPEVEEFYKKNHSGRKLHWHHLMSNGIITFKNEVGQYDLEVTTFQLAVLFAW 607
Query: 511 NDNTSWTV--RQLEQHTGIKGDFLIQVL-----------QILLKAKLLVCQEDEAELGEN 371
N + L+ T + L + L Q+LL + +D E
Sbjct: 608 NQRPREKISFENLKLATELPDAELRRTLWSLVAFPKLKRQVLLYEPQVNSPKDFTEGTLF 667
Query: 370 SVVDLYSGYKNKKL--RVNINIPLKTELKVE--QEATHKHIEEDRKMLIQAAIVRIMKTR 203
SV +S KN K+ R IN+ + +L E +E ++ I + R + Q AI++IMK R
Sbjct: 668 SVNQEFSLIKNAKVQKRGKINLIGRLQLTTERMREEENEGIVQLRILRTQEAIIQIMKMR 727
Query: 202 KTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDILIEKEYLERTEGEKDTYSYLA 41
K + + L E++ L + F P+ +IK+ I+ LIE +Y+ R E + +T+ Y+A
Sbjct: 728 KKISNAQLQTELVEILKNMFLPQKKMIKEQIEWLIEHKYIRRDESDINTFIYMA 781
>X81882-1|CAA57465.1| 780|Homo sapiens vasopressin activated calcium
mobilizing receptor-like protein protein.
Length = 780
Score = 92.3 bits (219), Expect = 2e-18
Identities = 73/234 (31%), Positives = 116/234 (49%), Gaps = 17/234 (7%)
Frame = -2
Query: 691 LPTEXERSVHRFTTFYSSQHSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAVLLQY 512
LPTE E + FY HSGRKL+W + MS G + +Y L+ +TFQ+AVL +
Sbjct: 547 LPTELEDLIPEVEEFYKKNHSGRKLHWHHLMSNGIITFKNEVGQYDLEVTTFQLAVLFAW 606
Query: 511 NDNTSWTV--RQLEQHTGIKGDFLIQVL-----------QILLKAKLLVCQEDEAELGEN 371
N + L+ T + L + L Q+ L + +D E
Sbjct: 607 NQRPREKISFENLKLATELPDAELRRTLWSLVAFPKLKRQVFLYDPQVNSPKDFTEGTLF 666
Query: 370 SVVDLYSGYKNKKL--RVNINIPLKTELKVEQ--EATHKHIEEDRKMLIQAAIVRIMKTR 203
SV +S KN K+ R IN+ + +L E+ E ++ I + R + Q AI++IMK R
Sbjct: 667 SVNQEFSLIKNAKVQKRGKINLIGRLQLTTERMREEENEGIVQLRILRTQEAIIQIMKMR 726
Query: 202 KTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDILIEKEYLERTEGEKDTYSYLA 41
K + + L E++ L + F P+ +IK+ I+ LIE +Y+ R E + +T+ Y+A
Sbjct: 727 KKISNAQLQTELVEILKNMFLPQKKMIKEQIEWLIEHKYIRRDESDINTFIYMA 780
>AL392046-3|CAI13164.1| 706|Homo sapiens cullin 2 protein.
Length = 706
Score = 82.2 bits (194), Expect = 2e-15
Identities = 39/136 (28%), Positives = 73/136 (53%)
Frame = -2
Query: 703 TSFQLPTEXERSVHRFTTFYSSQHSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAV 524
++F +P E E+SV F FYS SGRKL WL+ + GE+ N Y +T+QMAV
Sbjct: 525 STFAIPQELEKSVQMFELFYSQHFSGRKLTWLHYLCTGEVKMNYLGKPYVAMVTTYQMAV 584
Query: 523 LLQYNDNTSWTVRQLEQHTGIKGDFLIQVLQILLKAKLLVCQEDEAELGENSVVDLYSGY 344
LL +N++ + + ++L+ T + L + ++ LL K++ ++ ++ S L +
Sbjct: 585 LLAFNNSETVSYKELQDSTQMNEKELTKTIKSLLDVKMINHDSEKEDIDAESSFSLNMNF 644
Query: 343 KNKKLRVNINIPLKTE 296
+K+ + I ++ +
Sbjct: 645 SSKRTKFKITTSMQKD 660
Score = 57.2 bits (132), Expect = 5e-08
Identities = 24/57 (42%), Positives = 39/57 (68%)
Frame = -2
Query: 211 KTRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDILIEKEYLERTEGEKDTYSYLA 41
K + T Q +V++Q +RF P + +IKKCI++LI+K+Y+ER++ D YSY+A
Sbjct: 650 KFKITTSMQKDTPQVISQSRARFNPSISMIKKCIEVLIDKQYIERSQASADEYSYVA 706
>BC002879-1|AAH02879.2| 964|Homo sapiens PARC protein protein.
Length = 964
Score = 44.0 bits (99), Expect = 5e-04
Identities = 47/186 (25%), Positives = 80/186 (43%), Gaps = 10/186 (5%)
Frame = -2
Query: 691 LPTEXERSVHRFTTFYSSQHS--------GRKLNWLYNMSKGELLTNCFKNRYTLQASTF 536
LPTE ++ RF++FYS + R+L W + + + EL + L ST
Sbjct: 167 LPTEFCDALDRFSSFYSQSQNHPVLDMGPHRRLQWTW-LGRAELQF----GKQILHVSTV 221
Query: 535 QMAVLLQYNDNTSWTVRQLEQHTGIKGDFLIQVLQILLKAKLLVCQEDEAELGENSVVDL 356
QM +LL++N +V L + + + + L+Q L L + + + V+ L
Sbjct: 222 QMWLLLKFNQTEEVSVETLLKDSDLSPELLLQALVPLTSGNGPLTLHEGQDFPHGGVLRL 281
Query: 355 YSGYKNKKLRVNINIPLKTELKVEQEATHKHIEEDRKMLIQAAIVRIMKT--RKTLKHQH 182
+ + IP + L VE++ E ++ L+ +VRI+K K L
Sbjct: 282 HEPGPQRSGEALWLIPPQAYLNVEKD--EGRTLEQKRNLLSCLLVRILKAHGEKGLHIDQ 339
Query: 181 LVVEVL 164
LV VL
Sbjct: 340 LVCLVL 345
>AY145132-1|AAN61516.1| 2517|Homo sapiens p53-associated parkin-like
cytoplasmic protein protein.
Length = 2517
Score = 44.0 bits (99), Expect = 5e-04
Identities = 47/186 (25%), Positives = 80/186 (43%), Gaps = 10/186 (5%)
Frame = -2
Query: 691 LPTEXERSVHRFTTFYSSQHS--------GRKLNWLYNMSKGELLTNCFKNRYTLQASTF 536
LPTE ++ RF++FYS + R+L W + + + EL + L ST
Sbjct: 1720 LPTEFCDALDRFSSFYSQSQNHPVLDMGPHRRLQWTW-LGRAELQF----GKQILHVSTV 1774
Query: 535 QMAVLLQYNDNTSWTVRQLEQHTGIKGDFLIQVLQILLKAKLLVCQEDEAELGENSVVDL 356
QM +LL++N +V L + + + + L+Q L L + + + V+ L
Sbjct: 1775 QMWLLLKFNQTEEVSVETLLKDSDLSPELLLQALVPLTSGNGPLTLHEGQDFPHGGVLRL 1834
Query: 355 YSGYKNKKLRVNINIPLKTELKVEQEATHKHIEEDRKMLIQAAIVRIMKT--RKTLKHQH 182
+ + IP + L VE++ E ++ L+ +VRI+K K L
Sbjct: 1835 HEPGPQRSGEALWLIPPQAYLNVEKD--EGRTLEQKRNLLSCLLVRILKAHGEKGLHIDQ 1892
Query: 181 LVVEVL 164
LV VL
Sbjct: 1893 LVCLVL 1898
>AL133375-1|CAI20204.1| 2518|Homo sapiens RP3-330M21.2 protein.
Length = 2518
Score = 44.0 bits (99), Expect = 5e-04
Identities = 47/186 (25%), Positives = 80/186 (43%), Gaps = 10/186 (5%)
Frame = -2
Query: 691 LPTEXERSVHRFTTFYSSQHS--------GRKLNWLYNMSKGELLTNCFKNRYTLQASTF 536
LPTE ++ RF++FYS + R+L W + + + EL + L ST
Sbjct: 1720 LPTEFCDALDRFSSFYSQSQNHPVLDMGPHRRLQWTW-LGRAELQF----GKQILHVSTV 1774
Query: 535 QMAVLLQYNDNTSWTVRQLEQHTGIKGDFLIQVLQILLKAKLLVCQEDEAELGENSVVDL 356
QM +LL++N +V L + + + + L+Q L L + + + V+ L
Sbjct: 1775 QMWLLLKFNQTEEVSVETLLKDSDLSPELLLQALVPLTSGNGPLTLHEGQDFPHGGVLRL 1834
Query: 355 YSGYKNKKLRVNINIPLKTELKVEQEATHKHIEEDRKMLIQAAIVRIMKT--RKTLKHQH 182
+ + IP + L VE++ E ++ L+ +VRI+K K L
Sbjct: 1835 HEPGPQRSGEALWLIPPQAYLNVEKD--EGRTLEQKRNLLSCLLVRILKAHGEKGLHIDQ 1892
Query: 181 LVVEVL 164
LV VL
Sbjct: 1893 LVCLVL 1898
>AJ318215-1|CAC85756.1| 2517|Homo sapiens putative E3 ubiquitin ligase
protein.
Length = 2517
Score = 44.0 bits (99), Expect = 5e-04
Identities = 47/186 (25%), Positives = 80/186 (43%), Gaps = 10/186 (5%)
Frame = -2
Query: 691 LPTEXERSVHRFTTFYSSQHS--------GRKLNWLYNMSKGELLTNCFKNRYTLQASTF 536
LPTE ++ RF++FYS + R+L W + + + EL + L ST
Sbjct: 1720 LPTEFCDALDRFSSFYSQSQNHPVLDMGPHRRLQWTW-LGRAELQF----GKQILHVSTV 1774
Query: 535 QMAVLLQYNDNTSWTVRQLEQHTGIKGDFLIQVLQILLKAKLLVCQEDEAELGENSVVDL 356
QM +LL++N +V L + + + + L+Q L L + + + V+ L
Sbjct: 1775 QMWLLLKFNQTEEVSVETLLKDSDLSPELLLQALVPLTSGNGPLTLHEGQDFPHGGVLRL 1834
Query: 355 YSGYKNKKLRVNINIPLKTELKVEQEATHKHIEEDRKMLIQAAIVRIMKT--RKTLKHQH 182
+ + IP + L VE++ E ++ L+ +VRI+K K L
Sbjct: 1835 HEPGPQRSGEALWLIPPQAYLNVEKD--EGRTLEQKRNLLSCLLVRILKAHGEKGLHIDQ 1892
Query: 181 LVVEVL 164
LV VL
Sbjct: 1893 LVCLVL 1898
>AB014608-1|BAA31683.3| 1753|Homo sapiens KIAA0708 protein.
Length = 1753
Score = 44.0 bits (99), Expect = 5e-04
Identities = 47/186 (25%), Positives = 80/186 (43%), Gaps = 10/186 (5%)
Frame = -2
Query: 691 LPTEXERSVHRFTTFYSSQHS--------GRKLNWLYNMSKGELLTNCFKNRYTLQASTF 536
LPTE ++ RF++FYS + R+L W + + + EL + L ST
Sbjct: 956 LPTEFCDALDRFSSFYSQSQNHPVLDMGPHRRLQWTW-LGRAELQF----GKQILHVSTV 1010
Query: 535 QMAVLLQYNDNTSWTVRQLEQHTGIKGDFLIQVLQILLKAKLLVCQEDEAELGENSVVDL 356
QM +LL++N +V L + + + + L+Q L L + + + V+ L
Sbjct: 1011 QMWLLLKFNQTEEVSVETLLKDSDLSPELLLQALVPLTSGNGPLTLHEGQDFPHGGVLRL 1070
Query: 355 YSGYKNKKLRVNINIPLKTELKVEQEATHKHIEEDRKMLIQAAIVRIMKT--RKTLKHQH 182
+ + IP + L VE++ E ++ L+ +VRI+K K L
Sbjct: 1071 HEPGPQRSGEALWLIPPQAYLNVEKD--EGRTLEQKRNLLSCLLVRILKAHGEKGLHIDQ 1128
Query: 181 LVVEVL 164
LV VL
Sbjct: 1129 LVCLVL 1134
>BC062749-1|AAH62749.1| 383|Homo sapiens CCDC73 protein protein.
Length = 383
Score = 31.9 bits (69), Expect = 2.3
Identities = 25/94 (26%), Positives = 50/94 (53%), Gaps = 3/94 (3%)
Frame = -2
Query: 427 LLKAKLLVCQEDEAELGENSVVDLYSGYKNKKLRVNINIPLKTELKVEQEATHKHIEEDR 248
L+K+K+ CQ ++GE ++ K ++L+ +N+ L+ K+ +E T HI+E++
Sbjct: 138 LIKSKV-TCQY---KMGEENINLTIKEQKFQELQERLNMELELNEKINEEIT--HIQEEK 191
Query: 247 KMLIQAAI---VRIMKTRKTLKHQHLVVEVLNQL 155
+ L++ I + K LK + +E N+L
Sbjct: 192 QQLLRQQIQANTEMEAELKVLKENNQTLERDNEL 225
>BC032503-1|AAH32503.1| 822|Homo sapiens anaphase promoting complex
subunit 2 protein.
Length = 822
Score = 31.9 bits (69), Expect = 2.3
Identities = 13/74 (17%), Positives = 32/74 (43%)
Frame = -2
Query: 694 QLPTEXERSVHRFTTFYSSQHSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAVLLQ 515
++P + ++ + Y + R L+W + + + ++ + Q +LL
Sbjct: 610 EVPEDIRAALEAYCKKYEQLKAMRTLSWKHTLGLVTMDVELADRTLSVAVTPVQAVILLY 669
Query: 514 YNDNTSWTVRQLEQ 473
+ D SWT+ +L +
Sbjct: 670 FQDQASWTLEELSK 683
>BC001579-1|AAH01579.1| 577|Homo sapiens ANAPC2 protein protein.
Length = 577
Score = 31.9 bits (69), Expect = 2.3
Identities = 13/74 (17%), Positives = 32/74 (43%)
Frame = -2
Query: 694 QLPTEXERSVHRFTTFYSSQHSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAVLLQ 515
++P + ++ + Y + R L+W + + + ++ + Q +LL
Sbjct: 365 EVPEDIRAALEAYCKKYEQLKAMRTLSWKHTLGLVTMDVELADRTLSVAVTPVQAVILLY 424
Query: 514 YNDNTSWTVRQLEQ 473
+ D SWT+ +L +
Sbjct: 425 FQDQASWTLEELSK 438
>AL929554-12|CAH72881.1| 822|Homo sapiens anaphase promoting
complex subunit 2 protein.
Length = 822
Score = 31.9 bits (69), Expect = 2.3
Identities = 13/74 (17%), Positives = 32/74 (43%)
Frame = -2
Query: 694 QLPTEXERSVHRFTTFYSSQHSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAVLLQ 515
++P + ++ + Y + R L+W + + + ++ + Q +LL
Sbjct: 610 EVPEDIRAALEAYCKKYEQLKAMRTLSWKHTLGLVTMDVELADRTLSVAVTPVQAVILLY 669
Query: 514 YNDNTSWTVRQLEQ 473
+ D SWT+ +L +
Sbjct: 670 FQDQASWTLEELSK 683
>AF191337-1|AAF05751.1| 822|Homo sapiens anaphase-promoting complex
subunit 2 protein.
Length = 822
Score = 31.9 bits (69), Expect = 2.3
Identities = 13/74 (17%), Positives = 32/74 (43%)
Frame = -2
Query: 694 QLPTEXERSVHRFTTFYSSQHSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAVLLQ 515
++P + ++ + Y + R L+W + + + ++ + Q +LL
Sbjct: 610 EVPEDIRAALEAYCKKYEQLKAMRTLSWKHTLGLVTMDVELADRTLSVAVTPVQAVILLY 669
Query: 514 YNDNTSWTVRQLEQ 473
+ D SWT+ +L +
Sbjct: 670 FQDQASWTLEELSK 683
>AB037827-1|BAA92644.1| 571|Homo sapiens KIAA1406 protein protein.
Length = 571
Score = 31.9 bits (69), Expect = 2.3
Identities = 13/74 (17%), Positives = 32/74 (43%)
Frame = -2
Query: 694 QLPTEXERSVHRFTTFYSSQHSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAVLLQ 515
++P + ++ + Y + R L+W + + + ++ + Q +LL
Sbjct: 359 EVPEDIRAALEAYCKKYEQLKAMRTLSWKHTLGLVTMDVELADRTLSVAVTPVQAVILLY 418
Query: 514 YNDNTSWTVRQLEQ 473
+ D SWT+ +L +
Sbjct: 419 FQDQASWTLEELSK 432
>AK129846-1|BAC85241.1| 236|Homo sapiens protein ( Homo sapiens
cDNA FLJ26336 fis, clone HRT02842. ).
Length = 236
Score = 31.5 bits (68), Expect = 3.0
Identities = 13/39 (33%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Frame = +3
Query: 231 ACISIFLSSSMCLCVASCS-TLSSVFNGMFIFTRSFLFL 344
ACI +F S+ C+CV +C+ SVF ++ F+++
Sbjct: 142 ACICVFTSTHACICVFTCTHVYISVFTCTHVYICVFIYI 180
>U90920-1|AAB81012.1| 1261|Homo sapiens PTPL1-associated RhoGAP
protein.
Length = 1261
Score = 31.1 bits (67), Expect = 4.0
Identities = 33/136 (24%), Positives = 67/136 (49%), Gaps = 3/136 (2%)
Frame = -2
Query: 553 LQASTFQMAVLLQYNDNTSWTVRQLEQHTGIKGDFLIQVLQILLKAKLLVCQ-EDEAELG 377
LQA+ F +L + N+ +++++ + + +++ L KAKLL Q +DE E
Sbjct: 284 LQANKFVQPLLGRKNEMEKQR-KEIKELWKQEQNKMLEAENALKKAKLLCMQRQDEYEKA 342
Query: 376 ENSVVDLYSGYKNKK--LRVNINIPLKTELKVEQEATHKHIEEDRKMLIQAAIVRIMKTR 203
++S+ + + L N+N L+ + ++E+EA K E D L + + + + R
Sbjct: 343 KSSMFRAEEEHLSSSGGLAKNLNKQLEKKRRLEEEALQKVEEADE--LYKVCVTNVEERR 400
Query: 202 KTLKHQHLVVEVLNQL 155
+++ E+L QL
Sbjct: 401 NDVENTKR--EILAQL 414
>BC047885-1|AAH47885.1| 426|Homo sapiens SLK protein protein.
Length = 426
Score = 30.7 bits (66), Expect = 5.3
Identities = 42/209 (20%), Positives = 89/209 (42%), Gaps = 2/209 (0%)
Frame = -2
Query: 634 HSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAVLLQYNDNTSWTVRQLEQHTGIKG 455
H + L ++K E T +R++ F + L+ N + WT QL QH +
Sbjct: 236 HELNPMRVLLKIAKSEPPTLAQPSRWSSNFKDF-LKKCLEKNVDARWTTSQLLQHPFVTV 294
Query: 454 DFLIQVLQILLKAKLLVCQEDEAELGENSVVDLYSGYKNKKLRVNINIPLKTELKVEQEA 275
D + +++ +AK V +E E G+ ++++ ++P+ + +
Sbjct: 295 DSNKPIRELIAEAKAEV--TEEVEDGKE---------EDEEEETENSLPIPASKRASSDL 343
Query: 274 THKHIEEDRKMLIQAAIVRIM--KTRKTLKHQHLVVEVLNQLSSRFKPRVPVIKKCIDIL 101
+ EED K+ A I+ + KT ++ L ++LN+ KP +K ++ +
Sbjct: 344 SIASSEED-KLSQNACILESVSEKTERSNSEDKLNSKILNE-----KPTTDEPEKAVEDI 397
Query: 100 IEKEYLERTEGEKDTYSYLA*SRQRRRKK 14
E + E + + A +++++KK
Sbjct: 398 NEHITDAQLEAMTELHDRTAVIKEKKKKK 426
>AL135842-3|CAI23350.1| 118|Homo sapiens late cornified envelope 5A
protein.
Length = 118
Score = 30.3 bits (65), Expect = 7.0
Identities = 18/50 (36%), Positives = 23/50 (46%), Gaps = 2/50 (4%)
Frame = +1
Query: 364 QPSSRQAQPRPLDTPTVSPSIIFEAPV*GSPL*C--RCAAPAGGPSTRCC 507
Q S +Q QP P TP P + P P C +C+AP P + CC
Sbjct: 4 QQSQQQCQPPPKCTPKCPPKCTPKCPPKCPPK-CPPQCSAPCPPPVSSCC 52
>D86959-1|BAA13195.2| 1164|Homo sapiens KIAA0204 protein protein.
Length = 1164
Score = 29.9 bits (64), Expect = 9.3
Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 7/97 (7%)
Frame = -2
Query: 634 HSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAVLLQYNDNTSWTVRQLEQHTGIKG 455
H + L ++K E T +R++ F + L+ N + WT QL QH +
Sbjct: 248 HELNPMRVLLKIAKSEPPTLAQPSRWSSNFKDF-LKKCLEKNVDARWTTSQLLQHPFVTV 306
Query: 454 DFLIQVLQILLKAKLLVC-------QEDEAELGENSV 365
D + +++ +AK V +EDE E ENS+
Sbjct: 307 DSNKPIRELIAEAKAEVTEEVEDGKEEDEEEETENSL 343
>BC129951-1|AAI29952.1| 854|Homo sapiens MAP3K6 protein protein.
Length = 854
Score = 29.9 bits (64), Expect = 9.3
Identities = 12/23 (52%), Positives = 15/23 (65%)
Frame = +1
Query: 355 RDRQPSSRQAQPRPLDTPTVSPS 423
R R PSS + PRP D P+ SP+
Sbjct: 477 RSRSPSSPRHAPRPSDAPSASPT 499
>BC129950-1|AAI29951.1| 854|Homo sapiens MAP3K6 protein protein.
Length = 854
Score = 29.9 bits (64), Expect = 9.3
Identities = 12/23 (52%), Positives = 15/23 (65%)
Frame = +1
Query: 355 RDRQPSSRQAQPRPLDTPTVSPS 423
R R PSS + PRP D P+ SP+
Sbjct: 477 RSRSPSSPRHAPRPSDAPSASPT 499
>BC111565-1|AAI11566.1| 1204|Homo sapiens SLK protein protein.
Length = 1204
Score = 29.9 bits (64), Expect = 9.3
Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 7/97 (7%)
Frame = -2
Query: 634 HSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAVLLQYNDNTSWTVRQLEQHTGIKG 455
H + L ++K E T +R++ F + L+ N + WT QL QH +
Sbjct: 236 HELNPMRVLLKIAKSEPPTLAQPSRWSSNFKDF-LKKCLEKNVDARWTTSQLLQHPFVTV 294
Query: 454 DFLIQVLQILLKAKLLVC-------QEDEAELGENSV 365
D + +++ +AK V +EDE E ENS+
Sbjct: 295 DSNKPIRELIAEAKAEVTEEVEDGKEEDEEEETENSL 331
>BC109032-1|AAI09033.1| 441|Homo sapiens MAP3K6 protein protein.
Length = 441
Score = 29.9 bits (64), Expect = 9.3
Identities = 12/23 (52%), Positives = 15/23 (65%)
Frame = +1
Query: 355 RDRQPSSRQAQPRPLDTPTVSPS 423
R R PSS + PRP D P+ SP+
Sbjct: 380 RSRSPSSPRHAPRPSDAPSASPT 402
>BC064804-1|AAH64804.1| 617|Homo sapiens SLK protein protein.
Length = 617
Score = 29.9 bits (64), Expect = 9.3
Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 7/97 (7%)
Frame = -2
Query: 634 HSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAVLLQYNDNTSWTVRQLEQHTGIKG 455
H + L ++K E T +R++ F + L+ N + WT QL QH +
Sbjct: 236 HELNPMRVLLKIAKSEPPTLAQPSRWSSNFKDF-LKKCLEKNVDARWTTSQLLQHPFVTV 294
Query: 454 DFLIQVLQILLKAKLLVC-------QEDEAELGENSV 365
D + +++ +AK V +EDE E ENS+
Sbjct: 295 DSNKPIRELIAEAKAEVTEEVEDGKEEDEEEETENSL 331
>BC047762-1|AAH47762.1| 614|Homo sapiens SLK protein protein.
Length = 614
Score = 29.9 bits (64), Expect = 9.3
Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 7/97 (7%)
Frame = -2
Query: 634 HSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAVLLQYNDNTSWTVRQLEQHTGIKG 455
H + L ++K E T +R++ F + L+ N + WT QL QH +
Sbjct: 236 HELNPMRVLLKIAKSEPPTLAQPSRWSSNFKDF-LKKCLEKNVDARWTTSQLLQHPFVTV 294
Query: 454 DFLIQVLQILLKAKLLVC-------QEDEAELGENSV 365
D + +++ +AK V +EDE E ENS+
Sbjct: 295 DSNKPIRELIAEAKAEVTEEVEDGKEEDEEEETENSL 331
>BC015914-1|AAH15914.1| 797|Homo sapiens MAP3K6 protein protein.
Length = 797
Score = 29.9 bits (64), Expect = 9.3
Identities = 12/23 (52%), Positives = 15/23 (65%)
Frame = +1
Query: 355 RDRQPSSRQAQPRPLDTPTVSPS 423
R R PSS + PRP D P+ SP+
Sbjct: 634 RSRSPSSPRHAPRPSDAPSASPT 656
>AL663123-5|CAI14778.1| 797|Homo sapiens mitogen-activated protein
kinase kinase kinase 6 protein.
Length = 797
Score = 29.9 bits (64), Expect = 9.3
Identities = 12/23 (52%), Positives = 15/23 (65%)
Frame = +1
Query: 355 RDRQPSSRQAQPRPLDTPTVSPS 423
R R PSS + PRP D P+ SP+
Sbjct: 634 RSRSPSSPRHAPRPSDAPSASPT 656
>AL663123-4|CAM12869.1| 1288|Homo sapiens mitogen-activated protein
kinase kinase kinase 6 protein.
Length = 1288
Score = 29.9 bits (64), Expect = 9.3
Identities = 12/23 (52%), Positives = 15/23 (65%)
Frame = +1
Query: 355 RDRQPSSRQAQPRPLDTPTVSPS 423
R R PSS + PRP D P+ SP+
Sbjct: 911 RSRSPSSPRHAPRPSDAPSASPT 933
>AL360170-2|CAH70404.1| 1235|Homo sapiens Ste20-related
serine\/threonine kinase (SLK) protein.
Length = 1235
Score = 29.9 bits (64), Expect = 9.3
Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 7/97 (7%)
Frame = -2
Query: 634 HSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAVLLQYNDNTSWTVRQLEQHTGIKG 455
H + L ++K E T +R++ F + L+ N + WT QL QH +
Sbjct: 236 HELNPMRVLLKIAKSEPPTLAQPSRWSSNFKDF-LKKCLEKNVDARWTTSQLLQHPFVTV 294
Query: 454 DFLIQVLQILLKAKLLVC-------QEDEAELGENSV 365
D + +++ +AK V +EDE E ENS+
Sbjct: 295 DSNKPIRELIAEAKAEVTEEVEDGKEEDEEEETENSL 331
>AL360170-1|CAH70403.1| 1204|Homo sapiens Ste20-related
serine\/threonine kinase (SLK) protein.
Length = 1204
Score = 29.9 bits (64), Expect = 9.3
Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 7/97 (7%)
Frame = -2
Query: 634 HSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAVLLQYNDNTSWTVRQLEQHTGIKG 455
H + L ++K E T +R++ F + L+ N + WT QL QH +
Sbjct: 236 HELNPMRVLLKIAKSEPPTLAQPSRWSSNFKDF-LKKCLEKNVDARWTTSQLLQHPFVTV 294
Query: 454 DFLIQVLQILLKAKLLVC-------QEDEAELGENSV 365
D + +++ +AK V +EDE E ENS+
Sbjct: 295 DSNKPIRELIAEAKAEVTEEVEDGKEEDEEEETENSL 331
>AL138761-2|CAI12395.1| 1235|Homo sapiens Ste20-related
serine\/threonine kinase (SLK) protein.
Length = 1235
Score = 29.9 bits (64), Expect = 9.3
Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 7/97 (7%)
Frame = -2
Query: 634 HSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAVLLQYNDNTSWTVRQLEQHTGIKG 455
H + L ++K E T +R++ F + L+ N + WT QL QH +
Sbjct: 236 HELNPMRVLLKIAKSEPPTLAQPSRWSSNFKDF-LKKCLEKNVDARWTTSQLLQHPFVTV 294
Query: 454 DFLIQVLQILLKAKLLVC-------QEDEAELGENSV 365
D + +++ +AK V +EDE E ENS+
Sbjct: 295 DSNKPIRELIAEAKAEVTEEVEDGKEEDEEEETENSL 331
>AL138761-1|CAI12396.1| 1204|Homo sapiens Ste20-related
serine\/threonine kinase (SLK) protein.
Length = 1204
Score = 29.9 bits (64), Expect = 9.3
Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 7/97 (7%)
Frame = -2
Query: 634 HSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAVLLQYNDNTSWTVRQLEQHTGIKG 455
H + L ++K E T +R++ F + L+ N + WT QL QH +
Sbjct: 236 HELNPMRVLLKIAKSEPPTLAQPSRWSSNFKDF-LKKCLEKNVDARWTTSQLLQHPFVTV 294
Query: 454 DFLIQVLQILLKAKLLVC-------QEDEAELGENSV 365
D + +++ +AK V +EDE E ENS+
Sbjct: 295 DSNKPIRELIAEAKAEVTEEVEDGKEEDEEEETENSL 331
>AF273048-1|AAG34908.1| 1235|Homo sapiens CTCL tumor antigen se20-9
protein.
Length = 1235
Score = 29.9 bits (64), Expect = 9.3
Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 7/97 (7%)
Frame = -2
Query: 634 HSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAVLLQYNDNTSWTVRQLEQHTGIKG 455
H + L ++K E T +R++ F + L+ N + WT QL QH +
Sbjct: 236 HELNPMRVLLKIAKSEPPTLAQPSRWSSNFKDF-LKKCLEKNVDARWTTSQLLQHPFVTV 294
Query: 454 DFLIQVLQILLKAKLLVC-------QEDEAELGENSV 365
D + +++ +AK V +EDE E ENS+
Sbjct: 295 DSNKPIRELIAEAKAEVTEEVEDGKEEDEEEETENSL 331
>AF100318-1|AAD05304.1| 1011|Homo sapiens mitogen-activated protein
kinase kinase kinase 6 protein.
Length = 1011
Score = 29.9 bits (64), Expect = 9.3
Identities = 12/23 (52%), Positives = 15/23 (65%)
Frame = +1
Query: 355 RDRQPSSRQAQPRPLDTPTVSPS 423
R R PSS + PRP D P+ SP+
Sbjct: 634 RSRSPSSPRHAPRPSDAPSASPT 656
>AB208805-1|BAD92042.1| 1192|Homo sapiens mitogen-activated protein
kinase kinase kinase 6 variant protein.
Length = 1192
Score = 29.9 bits (64), Expect = 9.3
Identities = 12/23 (52%), Positives = 15/23 (65%)
Frame = +1
Query: 355 RDRQPSSRQAQPRPLDTPTVSPS 423
R R PSS + PRP D P+ SP+
Sbjct: 815 RSRSPSSPRHAPRPSDAPSASPT 837
>AB167411-1|BAD12485.1| 1288|Homo sapiens apoptosis
signal-regulating kinase 2 protein.
Length = 1288
Score = 29.9 bits (64), Expect = 9.3
Identities = 12/23 (52%), Positives = 15/23 (65%)
Frame = +1
Query: 355 RDRQPSSRQAQPRPLDTPTVSPS 423
R R PSS + PRP D P+ SP+
Sbjct: 911 RSRSPSSPRHAPRPSDAPSASPT 933
>AB002804-1|BAA19655.1| 1204|Homo sapiens hSLK protein.
Length = 1204
Score = 29.9 bits (64), Expect = 9.3
Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 7/97 (7%)
Frame = -2
Query: 634 HSGRKLNWLYNMSKGELLTNCFKNRYTLQASTFQMAVLLQYNDNTSWTVRQLEQHTGIKG 455
H + L ++K E T +R++ F + L+ N + WT QL QH +
Sbjct: 236 HELNPMRVLLKIAKSEPPTLAQPSRWSSNFKDF-LKKCLEKNVDARWTTSQLLQHPFVTV 294
Query: 454 DFLIQVLQILLKAKLLVC-------QEDEAELGENSV 365
D + +++ +AK V +EDE E ENS+
Sbjct: 295 DSNKPIRELIAEAKAEVTEEVEDGKEEDEEEETENSL 331
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 100,366,986
Number of Sequences: 237096
Number of extensions: 2261143
Number of successful extensions: 7745
Number of sequences better than 10.0: 78
Number of HSP's better than 10.0 without gapping: 7172
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7696
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8175213644
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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