Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P01_pT_F09
(729 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X98001-1|CAA66638.1| 331|Homo sapiens geranylgeranyl transferas... 360 3e-99
CR456941-1|CAG33222.1| 331|Homo sapiens RABGGTB protein. 360 3e-99
BC020790-1|AAH20790.1| 331|Homo sapiens Rab geranylgeranyltrans... 360 3e-99
AL357314-5|CAI22393.1| 331|Homo sapiens Rab geranylgeranyltrans... 360 3e-99
U49245-1|AAA91473.1| 331|Homo sapiens geranylgeranyl transferas... 358 1e-98
Y08201-1|CAA69383.1| 331|Homo sapiens rab geranylgeranyl transf... 355 7e-98
AB209023-1|BAD92260.1| 320|Homo sapiens Rab geranylgeranyltrans... 294 2e-79
L10414-1|AAA86286.1| 387|Homo sapiens farnesyl-protein transfer... 136 8e-32
L00635-1|AAA35854.1| 437|Homo sapiens farnesyl-protein transfer... 136 8e-32
BC020232-1|AAH20232.1| 437|Homo sapiens farnesyltransferase, CA... 136 8e-32
L25441-1|AAA35888.1| 377|Homo sapiens geranylgeranyltransferase... 123 8e-28
AL357314-4|CAI22392.1| 152|Homo sapiens Rab geranylgeranyltrans... 55 2e-07
AY780790-1|AAV98360.1| 300|Homo sapiens geranylgeranyltransfera... 46 2e-04
AJ277892-2|CAD12456.1|30017|Homo sapiens Titin protein. 30 9.8
AJ277892-1|CAD12455.1|26926|Homo sapiens N2B-Titin Isoform protein. 30 9.8
>X98001-1|CAA66638.1| 331|Homo sapiens geranylgeranyl transferase
II protein.
Length = 331
Score = 360 bits (885), Expect = 3e-99
Identities = 148/229 (64%), Positives = 188/229 (82%)
Frame = -1
Query: 729 SAVQVXAMYDRLDAVDIEGIVRYIVSLQQEDGSFYGDKWGEIDXRFSFCAVMCLSLLQRL 550
SAVQ+ +YD ++ +D+ +V Y+ LQ+EDGSF GD WGEID RFSFCAV L+LL +L
Sbjct: 100 SAVQILTLYDSINVIDVNKVVEYVKGLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKL 159
Query: 549 DAIDINKTVEFVLSCMNFDGGFGSKPGSESHAGLIYCCVGTLSICKRMDALHADELAWWL 370
DAI++ K +EFVLSCMNFDGGFG +PGSESHAG IYCC G L+I ++ +++D L WWL
Sbjct: 160 DAINVEKAIEFVLSCMNFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVNSDLLGWWL 219
Query: 369 CERQLPSGGLNGRPEKLPDLCYSWWVMSSLSMLNRIHWVDKKSLEEFILACQDYETGGFS 190
CERQLPSGGLNGRPEKLPD+CYSWWV++SL ++ R+HW+D++ L FILACQD ETGGF+
Sbjct: 220 CERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRLHWIDREKLRNFILACQDEETGGFA 279
Query: 189 DRPGDITDPFHTLFGLAGLSLLGNTSIKPVNPTYCMPQETIDRLKLKPQ 43
DRPGD+ DPFHTLFG+AGLSLLG IKPVNP +CMP+E + R+ ++P+
Sbjct: 280 DRPGDMVDPFHTLFGIAGLSLLGEEQIKPVNPVFCMPEEVLQRVNVQPE 328
Score = 71.3 bits (167), Expect = 3e-12
Identities = 48/199 (24%), Positives = 90/199 (45%)
Frame = -1
Query: 717 VXAMYDRLDAVDIEGIVRYIVSLQQEDGSFYGDKWGEIDXRFSFCAVMCLSLLQRLDAID 538
V + +L ++ E I+ +I S Q E G + ++ AV L+L ++ ID
Sbjct: 56 VMDLMGQLHRMNREEILAFIKSCQHECGGISASIGHDPHLLYTLSAVQILTLYDSINVID 115
Query: 537 INKTVEFVLSCMNFDGGFGSKPGSESHAGLIYCCVGTLSICKRMDALHADELAWWLCERQ 358
+NK VE+V DG F E +C V TL++ ++DA++ ++ ++
Sbjct: 116 VNKVVEYVKGLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCM 175
Query: 357 LPSGGLNGRPEKLPDLCYSWWVMSSLSMLNRIHWVDKKSLEEFILACQDYETGGFSDRPG 178
GG RP + L++ +++H V+ L ++ Q +GG + RP
Sbjct: 176 NFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVNSDLLGWWLCERQ-LPSGGLNGRPE 234
Query: 177 DITDPFHTLFGLAGLSLLG 121
+ D ++ + LA L ++G
Sbjct: 235 KLPDVCYSWWVLASLKIIG 253
>CR456941-1|CAG33222.1| 331|Homo sapiens RABGGTB protein.
Length = 331
Score = 360 bits (885), Expect = 3e-99
Identities = 148/229 (64%), Positives = 188/229 (82%)
Frame = -1
Query: 729 SAVQVXAMYDRLDAVDIEGIVRYIVSLQQEDGSFYGDKWGEIDXRFSFCAVMCLSLLQRL 550
SAVQ+ +YD ++ +D+ +V Y+ LQ+EDGSF GD WGEID RFSFCAV L+LL +L
Sbjct: 100 SAVQILTLYDSINVIDVNKVVEYVKGLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKL 159
Query: 549 DAIDINKTVEFVLSCMNFDGGFGSKPGSESHAGLIYCCVGTLSICKRMDALHADELAWWL 370
DAI++ K +EFVLSCMNFDGGFG +PGSESHAG IYCC G L+I ++ +++D L WWL
Sbjct: 160 DAINVEKAIEFVLSCMNFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVNSDLLGWWL 219
Query: 369 CERQLPSGGLNGRPEKLPDLCYSWWVMSSLSMLNRIHWVDKKSLEEFILACQDYETGGFS 190
CERQLPSGGLNGRPEKLPD+CYSWWV++SL ++ R+HW+D++ L FILACQD ETGGF+
Sbjct: 220 CERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRLHWIDREKLRNFILACQDEETGGFA 279
Query: 189 DRPGDITDPFHTLFGLAGLSLLGNTSIKPVNPTYCMPQETIDRLKLKPQ 43
DRPGD+ DPFHTLFG+AGLSLLG IKPVNP +CMP+E + R+ ++P+
Sbjct: 280 DRPGDMVDPFHTLFGIAGLSLLGEEQIKPVNPVFCMPEEVLQRVNVQPE 328
Score = 71.3 bits (167), Expect = 3e-12
Identities = 48/199 (24%), Positives = 90/199 (45%)
Frame = -1
Query: 717 VXAMYDRLDAVDIEGIVRYIVSLQQEDGSFYGDKWGEIDXRFSFCAVMCLSLLQRLDAID 538
V + +L ++ E I+ +I S Q E G + ++ AV L+L ++ ID
Sbjct: 56 VMDLMGQLHRMNREEILAFIKSCQHECGGISASIGHDPHLLYTLSAVQILTLYDSINVID 115
Query: 537 INKTVEFVLSCMNFDGGFGSKPGSESHAGLIYCCVGTLSICKRMDALHADELAWWLCERQ 358
+NK VE+V DG F E +C V TL++ ++DA++ ++ ++
Sbjct: 116 VNKVVEYVKGLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCM 175
Query: 357 LPSGGLNGRPEKLPDLCYSWWVMSSLSMLNRIHWVDKKSLEEFILACQDYETGGFSDRPG 178
GG RP + L++ +++H V+ L ++ Q +GG + RP
Sbjct: 176 NFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVNSDLLGWWLCERQ-LPSGGLNGRPE 234
Query: 177 DITDPFHTLFGLAGLSLLG 121
+ D ++ + LA L ++G
Sbjct: 235 KLPDVCYSWWVLASLKIIG 253
>BC020790-1|AAH20790.1| 331|Homo sapiens Rab
geranylgeranyltransferase, beta subunit protein.
Length = 331
Score = 360 bits (885), Expect = 3e-99
Identities = 148/229 (64%), Positives = 188/229 (82%)
Frame = -1
Query: 729 SAVQVXAMYDRLDAVDIEGIVRYIVSLQQEDGSFYGDKWGEIDXRFSFCAVMCLSLLQRL 550
SAVQ+ +YD ++ +D+ +V Y+ LQ+EDGSF GD WGEID RFSFCAV L+LL +L
Sbjct: 100 SAVQILTLYDSINVIDVNKVVEYVKGLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKL 159
Query: 549 DAIDINKTVEFVLSCMNFDGGFGSKPGSESHAGLIYCCVGTLSICKRMDALHADELAWWL 370
DAI++ K +EFVLSCMNFDGGFG +PGSESHAG IYCC G L+I ++ +++D L WWL
Sbjct: 160 DAINVEKAIEFVLSCMNFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVNSDLLGWWL 219
Query: 369 CERQLPSGGLNGRPEKLPDLCYSWWVMSSLSMLNRIHWVDKKSLEEFILACQDYETGGFS 190
CERQLPSGGLNGRPEKLPD+CYSWWV++SL ++ R+HW+D++ L FILACQD ETGGF+
Sbjct: 220 CERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRLHWIDREKLRNFILACQDEETGGFA 279
Query: 189 DRPGDITDPFHTLFGLAGLSLLGNTSIKPVNPTYCMPQETIDRLKLKPQ 43
DRPGD+ DPFHTLFG+AGLSLLG IKPVNP +CMP+E + R+ ++P+
Sbjct: 280 DRPGDMVDPFHTLFGIAGLSLLGEEQIKPVNPVFCMPEEVLQRVNVQPE 328
Score = 71.3 bits (167), Expect = 3e-12
Identities = 48/199 (24%), Positives = 90/199 (45%)
Frame = -1
Query: 717 VXAMYDRLDAVDIEGIVRYIVSLQQEDGSFYGDKWGEIDXRFSFCAVMCLSLLQRLDAID 538
V + +L ++ E I+ +I S Q E G + ++ AV L+L ++ ID
Sbjct: 56 VMDLMGQLHRMNREEILAFIKSCQHECGGISASIGHDPHLLYTLSAVQILTLYDSINVID 115
Query: 537 INKTVEFVLSCMNFDGGFGSKPGSESHAGLIYCCVGTLSICKRMDALHADELAWWLCERQ 358
+NK VE+V DG F E +C V TL++ ++DA++ ++ ++
Sbjct: 116 VNKVVEYVKGLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCM 175
Query: 357 LPSGGLNGRPEKLPDLCYSWWVMSSLSMLNRIHWVDKKSLEEFILACQDYETGGFSDRPG 178
GG RP + L++ +++H V+ L ++ Q +GG + RP
Sbjct: 176 NFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVNSDLLGWWLCERQ-LPSGGLNGRPE 234
Query: 177 DITDPFHTLFGLAGLSLLG 121
+ D ++ + LA L ++G
Sbjct: 235 KLPDVCYSWWVLASLKIIG 253
>AL357314-5|CAI22393.1| 331|Homo sapiens Rab
geranylgeranyltransferase, beta subunit protein.
Length = 331
Score = 360 bits (885), Expect = 3e-99
Identities = 148/229 (64%), Positives = 188/229 (82%)
Frame = -1
Query: 729 SAVQVXAMYDRLDAVDIEGIVRYIVSLQQEDGSFYGDKWGEIDXRFSFCAVMCLSLLQRL 550
SAVQ+ +YD ++ +D+ +V Y+ LQ+EDGSF GD WGEID RFSFCAV L+LL +L
Sbjct: 100 SAVQILTLYDSINVIDVNKVVEYVKGLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKL 159
Query: 549 DAIDINKTVEFVLSCMNFDGGFGSKPGSESHAGLIYCCVGTLSICKRMDALHADELAWWL 370
DAI++ K +EFVLSCMNFDGGFG +PGSESHAG IYCC G L+I ++ +++D L WWL
Sbjct: 160 DAINVEKAIEFVLSCMNFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVNSDLLGWWL 219
Query: 369 CERQLPSGGLNGRPEKLPDLCYSWWVMSSLSMLNRIHWVDKKSLEEFILACQDYETGGFS 190
CERQLPSGGLNGRPEKLPD+CYSWWV++SL ++ R+HW+D++ L FILACQD ETGGF+
Sbjct: 220 CERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRLHWIDREKLRNFILACQDEETGGFA 279
Query: 189 DRPGDITDPFHTLFGLAGLSLLGNTSIKPVNPTYCMPQETIDRLKLKPQ 43
DRPGD+ DPFHTLFG+AGLSLLG IKPVNP +CMP+E + R+ ++P+
Sbjct: 280 DRPGDMVDPFHTLFGIAGLSLLGEEQIKPVNPVFCMPEEVLQRVNVQPE 328
Score = 71.3 bits (167), Expect = 3e-12
Identities = 48/199 (24%), Positives = 90/199 (45%)
Frame = -1
Query: 717 VXAMYDRLDAVDIEGIVRYIVSLQQEDGSFYGDKWGEIDXRFSFCAVMCLSLLQRLDAID 538
V + +L ++ E I+ +I S Q E G + ++ AV L+L ++ ID
Sbjct: 56 VMDLMGQLHRMNREEILAFIKSCQHECGGISASIGHDPHLLYTLSAVQILTLYDSINVID 115
Query: 537 INKTVEFVLSCMNFDGGFGSKPGSESHAGLIYCCVGTLSICKRMDALHADELAWWLCERQ 358
+NK VE+V DG F E +C V TL++ ++DA++ ++ ++
Sbjct: 116 VNKVVEYVKGLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCM 175
Query: 357 LPSGGLNGRPEKLPDLCYSWWVMSSLSMLNRIHWVDKKSLEEFILACQDYETGGFSDRPG 178
GG RP + L++ +++H V+ L ++ Q +GG + RP
Sbjct: 176 NFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVNSDLLGWWLCERQ-LPSGGLNGRPE 234
Query: 177 DITDPFHTLFGLAGLSLLG 121
+ D ++ + LA L ++G
Sbjct: 235 KLPDVCYSWWVLASLKIIG 253
>U49245-1|AAA91473.1| 331|Homo sapiens geranylgeranyl transferase
type II beta-subunit protein.
Length = 331
Score = 358 bits (881), Expect = 1e-98
Identities = 147/229 (64%), Positives = 187/229 (81%)
Frame = -1
Query: 729 SAVQVXAMYDRLDAVDIEGIVRYIVSLQQEDGSFYGDKWGEIDXRFSFCAVMCLSLLQRL 550
SAVQ+ +YD ++ +D+ +V Y+ LQ+EDGSF GD WGEID RFSFCAV +LL +L
Sbjct: 100 SAVQILTLYDSINVIDVNKVVEYVKGLQKEDGSFAGDIWGEIDTRFSFCAVATFALLGKL 159
Query: 549 DAIDINKTVEFVLSCMNFDGGFGSKPGSESHAGLIYCCVGTLSICKRMDALHADELAWWL 370
DAI++ K +EFVLSCMNFDGGFG +PGSESHAG IYCC G L+I ++ +++D L WWL
Sbjct: 160 DAINVEKAIEFVLSCMNFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVNSDLLGWWL 219
Query: 369 CERQLPSGGLNGRPEKLPDLCYSWWVMSSLSMLNRIHWVDKKSLEEFILACQDYETGGFS 190
CERQLPSGGLNGRPEKLPD+CYSWWV++SL ++ R+HW+D++ L FILACQD ETGGF+
Sbjct: 220 CERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRLHWIDREKLRNFILACQDEETGGFA 279
Query: 189 DRPGDITDPFHTLFGLAGLSLLGNTSIKPVNPTYCMPQETIDRLKLKPQ 43
DRPGD+ DPFHTLFG+AGLSLLG IKPVNP +CMP+E + R+ ++P+
Sbjct: 280 DRPGDMVDPFHTLFGIAGLSLLGEEQIKPVNPVFCMPEEVLQRVNVQPE 328
Score = 69.7 bits (163), Expect = 1e-11
Identities = 47/199 (23%), Positives = 89/199 (44%)
Frame = -1
Query: 717 VXAMYDRLDAVDIEGIVRYIVSLQQEDGSFYGDKWGEIDXRFSFCAVMCLSLLQRLDAID 538
V + +L ++ E I+ +I S Q E G + ++ AV L+L ++ ID
Sbjct: 56 VMDLMGQLHRMNREEILAFIKSCQHECGGISASIGHDPHLLYTLSAVQILTLYDSINVID 115
Query: 537 INKTVEFVLSCMNFDGGFGSKPGSESHAGLIYCCVGTLSICKRMDALHADELAWWLCERQ 358
+NK VE+V DG F E +C V T ++ ++DA++ ++ ++
Sbjct: 116 VNKVVEYVKGLQKEDGSFAGDIWGEIDTRFSFCAVATFALLGKLDAINVEKAIEFVLSCM 175
Query: 357 LPSGGLNGRPEKLPDLCYSWWVMSSLSMLNRIHWVDKKSLEEFILACQDYETGGFSDRPG 178
GG RP + L++ +++H V+ L ++ Q +GG + RP
Sbjct: 176 NFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVNSDLLGWWLCERQ-LPSGGLNGRPE 234
Query: 177 DITDPFHTLFGLAGLSLLG 121
+ D ++ + LA L ++G
Sbjct: 235 KLPDVCYSWWVLASLKIIG 253
>Y08201-1|CAA69383.1| 331|Homo sapiens rab geranylgeranyl
transferase protein.
Length = 331
Score = 355 bits (874), Expect = 7e-98
Identities = 147/229 (64%), Positives = 186/229 (81%)
Frame = -1
Query: 729 SAVQVXAMYDRLDAVDIEGIVRYIVSLQQEDGSFYGDKWGEIDXRFSFCAVMCLSLLQRL 550
SAVQ+ +YD ++ +D+ +V Y+ LQ+EDGSF GD WGEID RFSFCAV L+LL +L
Sbjct: 100 SAVQILTLYDSINVIDVNKVVEYVKGLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKL 159
Query: 549 DAIDINKTVEFVLSCMNFDGGFGSKPGSESHAGLIYCCVGTLSICKRMDALHADELAWWL 370
DAI++ K +EFVLSCMN DGGFG +PGSESHAG IYCC G L+I ++ + +D L WWL
Sbjct: 160 DAINVEKAIEFVLSCMNSDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVTSDLLGWWL 219
Query: 369 CERQLPSGGLNGRPEKLPDLCYSWWVMSSLSMLNRIHWVDKKSLEEFILACQDYETGGFS 190
CERQLPSGGLNGRPEKLPD+CYSWWV++SL ++ R+HW+D++ L FILACQD ETGGF+
Sbjct: 220 CERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRLHWIDREKLRNFILACQDEETGGFA 279
Query: 189 DRPGDITDPFHTLFGLAGLSLLGNTSIKPVNPTYCMPQETIDRLKLKPQ 43
DRPGD+ DPFHTLFG+AGLSLLG IKPVNP +CMP+E + R+ ++P+
Sbjct: 280 DRPGDMVDPFHTLFGIAGLSLLGEEQIKPVNPVFCMPEEVLQRVNVQPE 328
Score = 71.7 bits (168), Expect = 2e-12
Identities = 48/199 (24%), Positives = 89/199 (44%)
Frame = -1
Query: 717 VXAMYDRLDAVDIEGIVRYIVSLQQEDGSFYGDKWGEIDXRFSFCAVMCLSLLQRLDAID 538
V + +L ++ E I+ +I S Q E G + ++ AV L+L ++ ID
Sbjct: 56 VMDLMGQLHRMNREEILAFIKSCQHECGGISASIGHDPHLLYTLSAVQILTLYDSINVID 115
Query: 537 INKTVEFVLSCMNFDGGFGSKPGSESHAGLIYCCVGTLSICKRMDALHADELAWWLCERQ 358
+NK VE+V DG F E +C V TL++ ++DA++ ++ ++
Sbjct: 116 VNKVVEYVKGLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCM 175
Query: 357 LPSGGLNGRPEKLPDLCYSWWVMSSLSMLNRIHWVDKKSLEEFILACQDYETGGFSDRPG 178
GG RP + L++ +++H V L ++ Q +GG + RP
Sbjct: 176 NSDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVTSDLLGWWLCERQ-LPSGGLNGRPE 234
Query: 177 DITDPFHTLFGLAGLSLLG 121
+ D ++ + LA L ++G
Sbjct: 235 KLPDVCYSWWVLASLKIIG 253
>AB209023-1|BAD92260.1| 320|Homo sapiens Rab
geranylgeranyltransferase, beta subunit variant protein.
Length = 320
Score = 294 bits (721), Expect = 2e-79
Identities = 121/186 (65%), Positives = 153/186 (82%)
Frame = -1
Query: 729 SAVQVXAMYDRLDAVDIEGIVRYIVSLQQEDGSFYGDKWGEIDXRFSFCAVMCLSLLQRL 550
SAVQ+ +YD ++ +D+ +V Y+ LQ+EDGSF GD WGEID RFSFCAV L+LL +L
Sbjct: 100 SAVQILTLYDSINVIDVNKVVEYVKGLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKL 159
Query: 549 DAIDINKTVEFVLSCMNFDGGFGSKPGSESHAGLIYCCVGTLSICKRMDALHADELAWWL 370
DAI++ K +EFVLSCMNFDGGFG +PGSESHAG IYCC G L+I ++ +++D L WWL
Sbjct: 160 DAINVEKAIEFVLSCMNFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVNSDLLGWWL 219
Query: 369 CERQLPSGGLNGRPEKLPDLCYSWWVMSSLSMLNRIHWVDKKSLEEFILACQDYETGGFS 190
CERQLPSGGLNGRPEKLPD+CYSWWV++SL ++ R+HW+D++ L FILACQD ETGGF+
Sbjct: 220 CERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRLHWIDREKLRNFILACQDEETGGFA 279
Query: 189 DRPGDI 172
DRPGD+
Sbjct: 280 DRPGDM 285
Score = 71.3 bits (167), Expect = 3e-12
Identities = 48/199 (24%), Positives = 90/199 (45%)
Frame = -1
Query: 717 VXAMYDRLDAVDIEGIVRYIVSLQQEDGSFYGDKWGEIDXRFSFCAVMCLSLLQRLDAID 538
V + +L ++ E I+ +I S Q E G + ++ AV L+L ++ ID
Sbjct: 56 VMDLMGQLHRMNREEILAFIKSCQHECGGISASIGHDPHLLYTLSAVQILTLYDSINVID 115
Query: 537 INKTVEFVLSCMNFDGGFGSKPGSESHAGLIYCCVGTLSICKRMDALHADELAWWLCERQ 358
+NK VE+V DG F E +C V TL++ ++DA++ ++ ++
Sbjct: 116 VNKVVEYVKGLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCM 175
Query: 357 LPSGGLNGRPEKLPDLCYSWWVMSSLSMLNRIHWVDKKSLEEFILACQDYETGGFSDRPG 178
GG RP + L++ +++H V+ L ++ Q +GG + RP
Sbjct: 176 NFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVNSDLLGWWLCERQ-LPSGGLNGRPE 234
Query: 177 DITDPFHTLFGLAGLSLLG 121
+ D ++ + LA L ++G
Sbjct: 235 KLPDVCYSWWVLASLKIIG 253
>L10414-1|AAA86286.1| 387|Homo sapiens farnesyl-protein transferase
beta-subunit protein.
Length = 387
Score = 136 bits (329), Expect = 8e-32
Identities = 75/215 (34%), Positives = 114/215 (53%), Gaps = 14/215 (6%)
Frame = -1
Query: 729 SAVQVXAMYDRLDAVDIEGIVRYIVSLQQEDGSFYGDKWGEIDXRFSFCAVMCLSLLQRL 550
+A+ + + D ++ E +++Y+ SL+Q DGSF GE+D R ++CA SL +
Sbjct: 108 NALCIIGTEEAYDIINREKLLQYLYSLKQPDGSFLMHVGGEVDVRSAYCAASVASLTNII 167
Query: 549 DAIDINKTVEFVLSCMNFDGGFGSKPGSESHAGLIYCCVGTLSICKRMDALHADELAWWL 370
T E++ C N++GG G PG E+H G +C + L I KR +L+ L W+
Sbjct: 168 TPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGGYTFCGLAALVILKRERSLNLKSLLQWV 227
Query: 369 CERQ-LPSGGLNGRPEKLPDLCYSWWVMSSLSMLNRI------------HWV-DKKSLEE 232
RQ L GG GR KL D CYS+W L +L+R HW+ +++L+E
Sbjct: 228 TSRQMLFEGGFQGRCNKLVDGCYSFWQAGLLPLLHRALHAQGDPALSMSHWMFHQQALQE 287
Query: 231 FILACQDYETGGFSDRPGDITDPFHTLFGLAGLSL 127
+IL C GG D+PG D +HT + L+GLS+
Sbjct: 288 YILMCCQCPAGGLLDKPGKSRDFYHTCYCLSGLSI 322
Score = 50.8 bits (116), Expect = 5e-06
Identities = 44/183 (24%), Positives = 78/183 (42%), Gaps = 3/183 (1%)
Frame = -1
Query: 672 IVRYIVSLQQEDGSFYGDKWGEIDXRFSFCAVMCLSLLQRLDAIDI---NKTVEFVLSCM 502
+ +++ Q +G F G ++ AV L ++ +A DI K ++++ S
Sbjct: 76 VCQFLELCQSPEGGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYDIINREKLLQYLYSLK 135
Query: 501 NFDGGFGSKPGSESHAGLIYCCVGTLSICKRMDALHADELAWWLCERQLPSGGLNGRPEK 322
DG F G E YC S+ + + A W+ Q GG+ G P
Sbjct: 136 QPDGSFLMHVGGEVDVRSAYCAASVASLTNIITPDLFEGTAEWIARCQNWEGGIGGVPGM 195
Query: 321 LPDLCYSWWVMSSLSMLNRIHWVDKKSLEEFILACQDYETGGFSDRPGDITDPFHTLFGL 142
Y++ +++L +L R ++ KSL +++ + Q GGF R + D ++ F
Sbjct: 196 EAHGGYTFCGLAALVILKRERSLNLKSLLQWVTSRQMLFEGGFQGRCNKLVDGCYS-FWQ 254
Query: 141 AGL 133
AGL
Sbjct: 255 AGL 257
>L00635-1|AAA35854.1| 437|Homo sapiens farnesyl-protein transferase
beta-subunit protein.
Length = 437
Score = 136 bits (329), Expect = 8e-32
Identities = 74/215 (34%), Positives = 114/215 (53%), Gaps = 14/215 (6%)
Frame = -1
Query: 729 SAVQVXAMYDRLDAVDIEGIVRYIVSLQQEDGSFYGDKWGEIDXRFSFCAVMCLSLLQRL 550
+A+ + + D ++ E +++Y+ SL+Q DGSF GE+D R ++CA SL +
Sbjct: 158 NALCIIGTEEAYDIINREKLLQYLYSLKQPDGSFLMHVGGEVDVRSAYCAASVASLTNII 217
Query: 549 DAIDINKTVEFVLSCMNFDGGFGSKPGSESHAGLIYCCVGTLSICKRMDALHADELAWWL 370
T E++ C N++GG G PG E+H G +C + L I KR +L+ L W+
Sbjct: 218 TPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGGYTFCGLAALVILKRERSLNLKSLLQWV 277
Query: 369 CERQLP-SGGLNGRPEKLPDLCYSWWVMSSLSMLNRI------------HWV-DKKSLEE 232
RQ+ GG GR KL D CYS+W L +L+R HW+ +++L+E
Sbjct: 278 TSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPLLHRALHAQGDPALSMSHWMFHQQALQE 337
Query: 231 FILACQDYETGGFSDRPGDITDPFHTLFGLAGLSL 127
+IL C GG D+PG D +HT + L+GLS+
Sbjct: 338 YILMCCQCPAGGLLDKPGKSRDFYHTCYCLSGLSI 372
Score = 50.4 bits (115), Expect = 6e-06
Identities = 44/183 (24%), Positives = 78/183 (42%), Gaps = 3/183 (1%)
Frame = -1
Query: 672 IVRYIVSLQQEDGSFYGDKWGEIDXRFSFCAVMCLSLLQRLDAIDI---NKTVEFVLSCM 502
+ +++ Q +G F G ++ AV L ++ +A DI K ++++ S
Sbjct: 126 VCQFLELCQSPEGGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYDIINREKLLQYLYSLK 185
Query: 501 NFDGGFGSKPGSESHAGLIYCCVGTLSICKRMDALHADELAWWLCERQLPSGGLNGRPEK 322
DG F G E YC S+ + + A W+ Q GG+ G P
Sbjct: 186 QPDGSFLMHVGGEVDVRSAYCAASVASLTNIITPDLFEGTAEWIARCQNWEGGIGGVPGM 245
Query: 321 LPDLCYSWWVMSSLSMLNRIHWVDKKSLEEFILACQDYETGGFSDRPGDITDPFHTLFGL 142
Y++ +++L +L R ++ KSL +++ + Q GGF R + D ++ F
Sbjct: 246 EAHGGYTFCGLAALVILKRERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYS-FWQ 304
Query: 141 AGL 133
AGL
Sbjct: 305 AGL 307
>BC020232-1|AAH20232.1| 437|Homo sapiens farnesyltransferase, CAAX
box, beta protein.
Length = 437
Score = 136 bits (329), Expect = 8e-32
Identities = 74/215 (34%), Positives = 114/215 (53%), Gaps = 14/215 (6%)
Frame = -1
Query: 729 SAVQVXAMYDRLDAVDIEGIVRYIVSLQQEDGSFYGDKWGEIDXRFSFCAVMCLSLLQRL 550
+A+ + + D ++ E +++Y+ SL+Q DGSF GE+D R ++CA SL +
Sbjct: 158 NALCIIGTEEAYDIINREKLLQYLYSLKQPDGSFLMHVGGEVDVRSAYCAASVASLTNII 217
Query: 549 DAIDINKTVEFVLSCMNFDGGFGSKPGSESHAGLIYCCVGTLSICKRMDALHADELAWWL 370
T E++ C N++GG G PG E+H G +C + L I KR +L+ L W+
Sbjct: 218 TPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGGYTFCGLAALVILKRERSLNLKSLLQWV 277
Query: 369 CERQLP-SGGLNGRPEKLPDLCYSWWVMSSLSMLNRI------------HWV-DKKSLEE 232
RQ+ GG GR KL D CYS+W L +L+R HW+ +++L+E
Sbjct: 278 TSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPLLHRALHAQGDPALSMSHWMFHQQALQE 337
Query: 231 FILACQDYETGGFSDRPGDITDPFHTLFGLAGLSL 127
+IL C GG D+PG D +HT + L+GLS+
Sbjct: 338 YILMCCQCPAGGLLDKPGKSRDFYHTCYCLSGLSI 372
Score = 50.4 bits (115), Expect = 6e-06
Identities = 44/183 (24%), Positives = 78/183 (42%), Gaps = 3/183 (1%)
Frame = -1
Query: 672 IVRYIVSLQQEDGSFYGDKWGEIDXRFSFCAVMCLSLLQRLDAIDI---NKTVEFVLSCM 502
+ +++ Q +G F G ++ AV L ++ +A DI K ++++ S
Sbjct: 126 VCQFLELCQSPEGGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYDIINREKLLQYLYSLK 185
Query: 501 NFDGGFGSKPGSESHAGLIYCCVGTLSICKRMDALHADELAWWLCERQLPSGGLNGRPEK 322
DG F G E YC S+ + + A W+ Q GG+ G P
Sbjct: 186 QPDGSFLMHVGGEVDVRSAYCAASVASLTNIITPDLFEGTAEWIARCQNWEGGIGGVPGM 245
Query: 321 LPDLCYSWWVMSSLSMLNRIHWVDKKSLEEFILACQDYETGGFSDRPGDITDPFHTLFGL 142
Y++ +++L +L R ++ KSL +++ + Q GGF R + D ++ F
Sbjct: 246 EAHGGYTFCGLAALVILKRERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYS-FWQ 304
Query: 141 AGL 133
AGL
Sbjct: 305 AGL 307
>L25441-1|AAA35888.1| 377|Homo sapiens geranylgeranyltransferase
type I beta-subunit protein.
Length = 377
Score = 123 bits (296), Expect = 8e-28
Identities = 69/220 (31%), Positives = 111/220 (50%), Gaps = 5/220 (2%)
Frame = -1
Query: 702 DRLDAVDIEGIVRYIVSLQQEDGSFYGDKWG-EIDXRFSFCAVMCLSLLQRLDAIDINKT 526
D L V+ E + + +LQ EDGSF G E D RF +CA +L +D+ K
Sbjct: 137 DDLSRVNKEACLAGLRALQLEDGSFCAVPEGSENDMRFVYCASCICYMLNNWSGMDMKKA 196
Query: 525 VEFVLSCMNFDGGFGSKPGSESHAGLIYCCVGTLSICKRMDALHADE----LAWWLCERQ 358
+ ++ M++D G G ESH G +C + +L + +++ + +++ + W RQ
Sbjct: 197 ITYIRRSMSYDNGLAQGAGLESHGGSTFCGIASLCLMGKLEEVFSEKELNRIKRWCIMRQ 256
Query: 357 LPSGGLNGRPEKLPDLCYSWWVMSSLSMLNRIHWVDKKSLEEFILACQDYETGGFSDRPG 178
G +GRP K D CYS+WV ++L +L + + + +IL+ QD GGF+ P
Sbjct: 257 --QNGYHGRPNKPVDTCYSFWVGATLKLLKIFQYTNFEKNRNYILSTQDRLVGGFAKWPD 314
Query: 177 DITDPFHTLFGLAGLSLLGNTSIKPVNPTYCMPQETIDRL 58
D H FG+ GLSL+ + I V+P + T +RL
Sbjct: 315 SHPDALHAYFGICGLSLMEESGICKVHPALNVSTRTSERL 354
>AL357314-4|CAI22392.1| 152|Homo sapiens Rab
geranylgeranyltransferase, beta subunit protein.
Length = 152
Score = 55.2 bits (127), Expect = 2e-07
Identities = 23/47 (48%), Positives = 33/47 (70%)
Frame = -1
Query: 729 SAVQVXAMYDRLDAVDIEGIVRYIVSLQQEDGSFYGDKWGEIDXRFS 589
SAVQ+ +YD ++ +D+ +V Y+ LQ+EDGSF GD WG + RFS
Sbjct: 100 SAVQILTLYDSINVIDVNKVVEYVKGLQKEDGSFAGDIWGNV--RFS 144
Score = 39.9 bits (89), Expect = 0.009
Identities = 23/78 (29%), Positives = 37/78 (47%)
Frame = -1
Query: 717 VXAMYDRLDAVDIEGIVRYIVSLQQEDGSFYGDKWGEIDXRFSFCAVMCLSLLQRLDAID 538
V + +L ++ E I+ +I S Q E G + ++ AV L+L ++ ID
Sbjct: 56 VMDLMGQLHRMNREEILAFIKSCQHECGGISASIGHDPHLLYTLSAVQILTLYDSINVID 115
Query: 537 INKTVEFVLSCMNFDGGF 484
+NK VE+V DG F
Sbjct: 116 VNKVVEYVKGLQKEDGSF 133
>AY780790-1|AAV98360.1| 300|Homo sapiens geranylgeranyltransferase
type I beta subunit protein.
Length = 300
Score = 45.6 bits (103), Expect = 2e-04
Identities = 26/75 (34%), Positives = 39/75 (52%), Gaps = 1/75 (1%)
Frame = -1
Query: 279 SMLNRI-HWVDKKSLEEFILACQDYETGGFSDRPGDITDPFHTLFGLAGLSLLGNTSIKP 103
SML +I + + + +IL+ QD GGF+ P D H FG+ GLSL+ + I
Sbjct: 203 SMLLKIFQYTNFEKNRNYILSTQDRLVGGFAKWPDSHPDALHAYFGICGLSLMEESGICK 262
Query: 102 VNPTYCMPQETIDRL 58
V+P + T +RL
Sbjct: 263 VHPALNVSTRTSERL 277
>AJ277892-2|CAD12456.1|30017|Homo sapiens Titin protein.
Length = 30000
Score = 29.9 bits (64), Expect = 9.8
Identities = 18/52 (34%), Positives = 27/52 (51%), Gaps = 4/52 (7%)
Frame = +2
Query: 449 RPAWLSDPGLEPNPPSKF--MQLSTNSTVL--LMSMASNRCKSDRHITAQKE 592
+P SDP EP+PP K +++ NS L L + K D +IT+ +E
Sbjct: 19715 KPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYRE 19766
>AJ277892-1|CAD12455.1|26926|Homo sapiens N2B-Titin Isoform protein.
Length = 26926
Score = 29.9 bits (64), Expect = 9.8
Identities = 18/52 (34%), Positives = 27/52 (51%), Gaps = 4/52 (7%)
Frame = +2
Query: 449 RPAWLSDPGLEPNPPSKF--MQLSTNSTVL--LMSMASNRCKSDRHITAQKE 592
+P SDP EP+PP K +++ NS L L + K D +IT+ +E
Sbjct: 12291 KPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYRE 12342
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 120,437,799
Number of Sequences: 237096
Number of extensions: 2906760
Number of successful extensions: 5946
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 5638
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5914
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8623170556
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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