Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P01_pT_E12
(743 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
J05262-1|AAA52423.1| 353|Homo sapiens FDPS protein. 184 3e-46
M29863-1|AAA35820.1| 346|Homo sapiens protein ( Human farnesyl ... 183 5e-46
D14697-1|BAA03523.2| 420|Homo sapiens KIAA1293 protein. 183 5e-46
BC010004-1|AAH10004.1| 419|Homo sapiens farnesyl diphosphate sy... 183 5e-46
AL139410-1|CAI12715.1| 419|Homo sapiens farnesyl diphosphate sy... 183 5e-46
Z47055-1|CAA87327.1| 348|Homo sapiens farnesyl pyrophosphate sy... 166 8e-41
BC050292-1|AAH50292.1| 298|Homo sapiens LOC619190 protein protein. 155 2e-37
M87434-1|AAA60607.1| 727|Homo sapiens 71 kDa 2'5' oligoadenylat... 30 7.6
M87284-1|AAA60606.1| 687|Homo sapiens 2'5' oligoadenylate synth... 30 7.6
BC049215-1|AAH49215.1| 687|Homo sapiens 2'-5'-oligoadenylate sy... 30 7.6
>J05262-1|AAA52423.1| 353|Homo sapiens FDPS protein.
Length = 353
Score = 184 bits (448), Expect = 3e-46
Identities = 93/229 (40%), Positives = 132/229 (57%), Gaps = 1/229 (0%)
Frame = -3
Query: 741 DDIMDGSSVRXGMPCWYRRPEVGITCAFNDSLLIHSSLFEFLKTNFRTNPNYMKMFELFN 562
DDIMD S R G CWY++P VG+ A ND+ L+ + ++ LK R P Y+ + ELF
Sbjct: 103 DDIMDSSLTRRGQTCWYQKPGVGLD-AINDANLLEACIYRLLKLYCREQPYYLNLIELFL 161
Query: 561 ETLWRTSMGQHLDHVTGNRXT-DYSSFTLDRXXXXXXXXXXXXXYNLPVSLGLLLAENVD 385
++ ++T +GQ LD +T + D FT R + LP++ + +A
Sbjct: 162 QSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDG 221
Query: 384 EKIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAVQALQRCTEA 205
EK + +A+ I LE+G FQIQDD++D FGD TGK+GTDIQ+ KC+WL VQ LQR T
Sbjct: 222 EKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPE 281
Query: 204 QRTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIE 58
Q + K YG E V R+K LYE+L LP ++ E+ Y +I+ IE
Sbjct: 282 QYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIE 330
>M29863-1|AAA35820.1| 346|Homo sapiens protein ( Human farnesyl
pyrophosphate synthetase mRNA (hpt807), 3' end. ).
Length = 346
Score = 183 bits (446), Expect = 5e-46
Identities = 93/229 (40%), Positives = 132/229 (57%), Gaps = 1/229 (0%)
Frame = -3
Query: 741 DDIMDGSSVRXGMPCWYRRPEVGITCAFNDSLLIHSSLFEFLKTNFRTNPNYMKMFELFN 562
DDIMD S R G CWY++P VG+ A ND+ L+ + ++ LK R P Y+ + ELF
Sbjct: 96 DDIMDSSLTRRGQICWYQKPGVGLD-AINDANLLEACIYRLLKLYCREQPYYLNLIELFL 154
Query: 561 ETLWRTSMGQHLDHVTGNRXT-DYSSFTLDRXXXXXXXXXXXXXYNLPVSLGLLLAENVD 385
++ ++T +GQ LD +T + D FT R + LP++ + +A
Sbjct: 155 QSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDG 214
Query: 384 EKIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAVQALQRCTEA 205
EK + +A+ I LE+G FQIQDD++D FGD TGK+GTDIQ+ KC+WL VQ LQR T
Sbjct: 215 EKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPE 274
Query: 204 QRTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIE 58
Q + K YG E V R+K LYE+L LP ++ E+ Y +I+ IE
Sbjct: 275 QYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIE 323
>D14697-1|BAA03523.2| 420|Homo sapiens KIAA1293 protein.
Length = 420
Score = 183 bits (446), Expect = 5e-46
Identities = 93/229 (40%), Positives = 132/229 (57%), Gaps = 1/229 (0%)
Frame = -3
Query: 741 DDIMDGSSVRXGMPCWYRRPEVGITCAFNDSLLIHSSLFEFLKTNFRTNPNYMKMFELFN 562
DDIMD S R G CWY++P VG+ A ND+ L+ + ++ LK R P Y+ + ELF
Sbjct: 170 DDIMDSSLTRRGQICWYQKPGVGLD-AINDANLLEACIYRLLKLYCREQPYYLNLIELFL 228
Query: 561 ETLWRTSMGQHLDHVTGNRXT-DYSSFTLDRXXXXXXXXXXXXXYNLPVSLGLLLAENVD 385
++ ++T +GQ LD +T + D FT R + LP++ + +A
Sbjct: 229 QSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDG 288
Query: 384 EKIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAVQALQRCTEA 205
EK + +A+ I LE+G FQIQDD++D FGD TGK+GTDIQ+ KC+WL VQ LQR T
Sbjct: 289 EKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPE 348
Query: 204 QRTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIE 58
Q + K YG E V R+K LYE+L LP ++ E+ Y +I+ IE
Sbjct: 349 QYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIE 397
>BC010004-1|AAH10004.1| 419|Homo sapiens farnesyl diphosphate
synthase (farnesyl pyrophosphate synthetase,
dimethylallyl protein.
Length = 419
Score = 183 bits (446), Expect = 5e-46
Identities = 93/229 (40%), Positives = 132/229 (57%), Gaps = 1/229 (0%)
Frame = -3
Query: 741 DDIMDGSSVRXGMPCWYRRPEVGITCAFNDSLLIHSSLFEFLKTNFRTNPNYMKMFELFN 562
DDIMD S R G CWY++P VG+ A ND+ L+ + ++ LK R P Y+ + ELF
Sbjct: 169 DDIMDSSLTRRGQICWYQKPGVGLD-AINDANLLEACIYRLLKLYCREQPYYLNLIELFL 227
Query: 561 ETLWRTSMGQHLDHVTGNRXT-DYSSFTLDRXXXXXXXXXXXXXYNLPVSLGLLLAENVD 385
++ ++T +GQ LD +T + D FT R + LP++ + +A
Sbjct: 228 QSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDG 287
Query: 384 EKIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAVQALQRCTEA 205
EK + +A+ I LE+G FQIQDD++D FGD TGK+GTDIQ+ KC+WL VQ LQR T
Sbjct: 288 EKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPE 347
Query: 204 QRTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIE 58
Q + K YG E V R+K LYE+L LP ++ E+ Y +I+ IE
Sbjct: 348 QYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIE 396
>AL139410-1|CAI12715.1| 419|Homo sapiens farnesyl diphosphate
synthase (farnesyl pyrophosphate synthetase,
dimethylallyl protein.
Length = 419
Score = 183 bits (446), Expect = 5e-46
Identities = 93/229 (40%), Positives = 132/229 (57%), Gaps = 1/229 (0%)
Frame = -3
Query: 741 DDIMDGSSVRXGMPCWYRRPEVGITCAFNDSLLIHSSLFEFLKTNFRTNPNYMKMFELFN 562
DDIMD S R G CWY++P VG+ A ND+ L+ + ++ LK R P Y+ + ELF
Sbjct: 169 DDIMDSSLTRRGQICWYQKPGVGLD-AINDANLLEACIYRLLKLYCREQPYYLNLIELFL 227
Query: 561 ETLWRTSMGQHLDHVTGNRXT-DYSSFTLDRXXXXXXXXXXXXXYNLPVSLGLLLAENVD 385
++ ++T +GQ LD +T + D FT R + LP++ + +A
Sbjct: 228 QSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDG 287
Query: 384 EKIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAVQALQRCTEA 205
EK + +A+ I LE+G FQIQDD++D FGD TGK+GTDIQ+ KC+WL VQ LQR T
Sbjct: 288 EKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPE 347
Query: 204 QRTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIE 58
Q + K YG E V R+K LYE+L LP ++ E+ Y +I+ IE
Sbjct: 348 QYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIE 396
>Z47055-1|CAA87327.1| 348|Homo sapiens farnesyl pyrophosphate
synthetase like-4 protein.
Length = 348
Score = 166 bits (403), Expect = 8e-41
Identities = 88/229 (38%), Positives = 124/229 (54%), Gaps = 1/229 (0%)
Frame = -3
Query: 741 DDIMDGSSVRXGMPCWYRRPEVGITCAFNDSLLIHSSLFEFLKTNFRTNPNYMKMFELFN 562
DDIMD S R G CWY++P VG+ A +D+ L+ + ++ LK R P Y+ + ELF
Sbjct: 98 DDIMDSSLTRRGQICWYQKPGVGLD-AIDDANLLEACIYPLLKLYCREQPYYLNLIELFL 156
Query: 561 ETLWRTSMGQHLDHVTGNRXT-DYSSFTLDRXXXXXXXXXXXXXYNLPVSLGLLLAENVD 385
++ ++T +GQ LD +T + D FT R LP++ V
Sbjct: 157 QSSYQTEIGQTLDLLTXPQGNVDLVRFTEKRYISIVKYKTALSSSYLPIAAAXXXXGIVX 216
Query: 384 EKIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAVQALQRCTEA 205
EK + +A I LE+G QIQDD+++ FGD TGK+GTDIQ+ KC L VQ L R T
Sbjct: 217 EKEHANAXKILLEMGEFSQIQDDYLELFGDPSVTGKIGTDIQDXKCNCLXVQCLXRATPE 276
Query: 204 QRTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIE 58
Q + K YG E V R+K LYE+L LP ++ E+ Y +I+ IE
Sbjct: 277 QYQILKENYGQKEAEKVPRVKALYEELDLPAVFLQYEEDSYSHIMALIE 325
>BC050292-1|AAH50292.1| 298|Homo sapiens LOC619190 protein protein.
Length = 298
Score = 155 bits (376), Expect = 2e-37
Identities = 83/229 (36%), Positives = 123/229 (53%), Gaps = 1/229 (0%)
Frame = -3
Query: 741 DDIMDGSSVRXGMPCWYRRPEVGITCAFNDSLLIHSSLFEFLKTNFRTNPNYMKMFELFN 562
DDIMD S G WY++ +G+ A ND++L+ + ++ LK R P Y+ + ELF
Sbjct: 71 DDIMDSSLTCQGQISWYQKLGMGLD-AINDAILLEACIYCLLKLYCREQPYYLNLMELFQ 129
Query: 561 ETLWRTSMGQHLDHVTGNRXT-DYSSFTLDRXXXXXXXXXXXXXYNLPVSLGLLLAENVD 385
+ ++T +GQ LD +T + D T R + LPV+ + ++ D
Sbjct: 130 QNSYQTEIGQTLDLITTPQGNVDLRRCTEKRHKSVVKYKTAFYSFYLPVAAAMYMSRMDD 189
Query: 384 EKIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAVQALQRCTEA 205
+K + SA+ I LEI FQIQDD++D GD TG+VG D Q+ KC+WL VQ L + T
Sbjct: 190 KKEHTSAKKILLEIQEFFQIQDDYLDFSGDPSVTGRVGNDFQDNKCSWLVVQCLLQATPE 249
Query: 204 QRTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIE 58
Q + K Y E V R+K LYE+L LP ++ EK Y +++ IE
Sbjct: 250 QYQILKENYRQKEAEKVARVKALYEELDLPAVFLQYEKDSYSHVMGLIE 298
>M87434-1|AAA60607.1| 727|Homo sapiens 71 kDa 2'5' oligoadenylate
synthetase protein.
Length = 727
Score = 30.3 bits (65), Expect = 7.6
Identities = 12/31 (38%), Positives = 20/31 (64%)
Frame = -1
Query: 275 LVQIYKSANVLGWQFKRCSAVLKHNVQYSKP 183
L+ +YKS+++ G +F C VL+ N S+P
Sbjct: 506 LIDLYKSSDLPGGEFSTCFTVLQRNFIRSRP 536
>M87284-1|AAA60606.1| 687|Homo sapiens 2'5' oligoadenylate
synthetase protein.
Length = 687
Score = 30.3 bits (65), Expect = 7.6
Identities = 12/31 (38%), Positives = 20/31 (64%)
Frame = -1
Query: 275 LVQIYKSANVLGWQFKRCSAVLKHNVQYSKP 183
L+ +YKS+++ G +F C VL+ N S+P
Sbjct: 506 LIDLYKSSDLPGGEFSTCFTVLQRNFIRSRP 536
>BC049215-1|AAH49215.1| 687|Homo sapiens 2'-5'-oligoadenylate
synthetase 2, 69/71kDa protein.
Length = 687
Score = 30.3 bits (65), Expect = 7.6
Identities = 12/31 (38%), Positives = 20/31 (64%)
Frame = -1
Query: 275 LVQIYKSANVLGWQFKRCSAVLKHNVQYSKP 183
L+ +YKS+++ G +F C VL+ N S+P
Sbjct: 506 LIDLYKSSDLPGGEFSTCFTVLQRNFIRSRP 536
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 104,695,102
Number of Sequences: 237096
Number of extensions: 2060868
Number of successful extensions: 4020
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3891
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4006
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8903143626
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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