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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= fcaL-P01_pT_D05
         (793 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

M29863-1|AAA35820.1|  346|Homo sapiens protein ( Human farnesyl ...   121   3e-27
J05262-1|AAA52423.1|  353|Homo sapiens FDPS protein.                  121   3e-27
D14697-1|BAA03523.2|  420|Homo sapiens KIAA1293 protein.              121   3e-27
BC010004-1|AAH10004.1|  419|Homo sapiens farnesyl diphosphate sy...   121   3e-27
AL139410-1|CAI12715.1|  419|Homo sapiens farnesyl diphosphate sy...   121   3e-27
Z47055-1|CAA87327.1|  348|Homo sapiens farnesyl pyrophosphate sy...   106   1e-22
BC050292-1|AAH50292.1|  298|Homo sapiens LOC619190 protein protein.   103   6e-22
M87434-1|AAA60607.1|  727|Homo sapiens 71 kDa 2'5' oligoadenylat...    30   8.3  
M87284-1|AAA60606.1|  687|Homo sapiens 2'5' oligoadenylate synth...    30   8.3  
BC049215-1|AAH49215.1|  687|Homo sapiens 2'-5'-oligoadenylate sy...    30   8.3  

>M29863-1|AAA35820.1|  346|Homo sapiens protein ( Human farnesyl
           pyrophosphate synthetase mRNA (hpt807), 3' end. ).
          Length = 346

 Score =  121 bits (291), Expect = 3e-27
 Identities = 60/144 (41%), Positives = 81/144 (56%)
 Frame = -3

Query: 473 PFXLGLLLAENVDEKIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCT 294
           P    + +A    EK + +A+ I LE+G  FQIQDD++D FGD   TGK+GTDIQ+ KC+
Sbjct: 202 PIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCS 261

Query: 293 WLAVQALQRCTEAQRTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQ 114
           WL VQ LQR T  Q  + K  YG  E   V R+K LYE+L LP ++   E+  Y +I+  
Sbjct: 262 WLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMAL 321

Query: 113 IENITIEAARVLFKKLLDITYNRQ 42
           IE         +F  L    Y R+
Sbjct: 322 IEQYAAPLPPAVFLGLARKIYKRR 345



 Score = 53.2 bits (122), Expect = 1e-06
 Identities = 29/99 (29%), Positives = 48/99 (48%), Gaps = 1/99 (1%)
 Frame = -2

Query: 762 RGMPCWYRRPEVGITCAFXDSLLIHSSLFEFXXTNFRTNPNYIKMFELFNETLWRTSMGQ 583
           RG  CWY++P VG+  A  D+ L+ + ++       R  P Y+ + ELF ++ ++T +GQ
Sbjct: 106 RGQICWYQKPGVGLD-AINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQ 164

Query: 582 HLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYNLPV 469
            LD +T  +   D   FT  R             + LP+
Sbjct: 165 TLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPI 203


>J05262-1|AAA52423.1|  353|Homo sapiens FDPS protein.
          Length = 353

 Score =  121 bits (291), Expect = 3e-27
 Identities = 60/144 (41%), Positives = 81/144 (56%)
 Frame = -3

Query: 473 PFXLGLLLAENVDEKIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCT 294
           P    + +A    EK + +A+ I LE+G  FQIQDD++D FGD   TGK+GTDIQ+ KC+
Sbjct: 209 PIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCS 268

Query: 293 WLAVQALQRCTEAQRTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQ 114
           WL VQ LQR T  Q  + K  YG  E   V R+K LYE+L LP ++   E+  Y +I+  
Sbjct: 269 WLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMAL 328

Query: 113 IENITIEAARVLFKKLLDITYNRQ 42
           IE         +F  L    Y R+
Sbjct: 329 IEQYAAPLPPAVFLGLARKIYKRR 352



 Score = 54.0 bits (124), Expect = 6e-07
 Identities = 29/99 (29%), Positives = 48/99 (48%), Gaps = 1/99 (1%)
 Frame = -2

Query: 762 RGMPCWYRRPEVGITCAFXDSLLIHSSLFEFXXTNFRTNPNYIKMFELFNETLWRTSMGQ 583
           RG  CWY++P VG+  A  D+ L+ + ++       R  P Y+ + ELF ++ ++T +GQ
Sbjct: 113 RGQTCWYQKPGVGLD-AINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQ 171

Query: 582 HLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYNLPV 469
            LD +T  +   D   FT  R             + LP+
Sbjct: 172 TLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPI 210


>D14697-1|BAA03523.2|  420|Homo sapiens KIAA1293 protein.
          Length = 420

 Score =  121 bits (291), Expect = 3e-27
 Identities = 60/144 (41%), Positives = 81/144 (56%)
 Frame = -3

Query: 473 PFXLGLLLAENVDEKIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCT 294
           P    + +A    EK + +A+ I LE+G  FQIQDD++D FGD   TGK+GTDIQ+ KC+
Sbjct: 276 PIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCS 335

Query: 293 WLAVQALQRCTEAQRTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQ 114
           WL VQ LQR T  Q  + K  YG  E   V R+K LYE+L LP ++   E+  Y +I+  
Sbjct: 336 WLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMAL 395

Query: 113 IENITIEAARVLFKKLLDITYNRQ 42
           IE         +F  L    Y R+
Sbjct: 396 IEQYAAPLPPAVFLGLARKIYKRR 419



 Score = 53.2 bits (122), Expect = 1e-06
 Identities = 29/99 (29%), Positives = 48/99 (48%), Gaps = 1/99 (1%)
 Frame = -2

Query: 762 RGMPCWYRRPEVGITCAFXDSLLIHSSLFEFXXTNFRTNPNYIKMFELFNETLWRTSMGQ 583
           RG  CWY++P VG+  A  D+ L+ + ++       R  P Y+ + ELF ++ ++T +GQ
Sbjct: 180 RGQICWYQKPGVGLD-AINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQ 238

Query: 582 HLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYNLPV 469
            LD +T  +   D   FT  R             + LP+
Sbjct: 239 TLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPI 277


>BC010004-1|AAH10004.1|  419|Homo sapiens farnesyl diphosphate
           synthase (farnesyl pyrophosphate synthetase,
           dimethylallyl protein.
          Length = 419

 Score =  121 bits (291), Expect = 3e-27
 Identities = 60/144 (41%), Positives = 81/144 (56%)
 Frame = -3

Query: 473 PFXLGLLLAENVDEKIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCT 294
           P    + +A    EK + +A+ I LE+G  FQIQDD++D FGD   TGK+GTDIQ+ KC+
Sbjct: 275 PIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCS 334

Query: 293 WLAVQALQRCTEAQRTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQ 114
           WL VQ LQR T  Q  + K  YG  E   V R+K LYE+L LP ++   E+  Y +I+  
Sbjct: 335 WLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMAL 394

Query: 113 IENITIEAARVLFKKLLDITYNRQ 42
           IE         +F  L    Y R+
Sbjct: 395 IEQYAAPLPPAVFLGLARKIYKRR 418



 Score = 53.2 bits (122), Expect = 1e-06
 Identities = 29/99 (29%), Positives = 48/99 (48%), Gaps = 1/99 (1%)
 Frame = -2

Query: 762 RGMPCWYRRPEVGITCAFXDSLLIHSSLFEFXXTNFRTNPNYIKMFELFNETLWRTSMGQ 583
           RG  CWY++P VG+  A  D+ L+ + ++       R  P Y+ + ELF ++ ++T +GQ
Sbjct: 179 RGQICWYQKPGVGLD-AINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQ 237

Query: 582 HLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYNLPV 469
            LD +T  +   D   FT  R             + LP+
Sbjct: 238 TLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPI 276


>AL139410-1|CAI12715.1|  419|Homo sapiens farnesyl diphosphate
           synthase (farnesyl pyrophosphate synthetase,
           dimethylallyl protein.
          Length = 419

 Score =  121 bits (291), Expect = 3e-27
 Identities = 60/144 (41%), Positives = 81/144 (56%)
 Frame = -3

Query: 473 PFXLGLLLAENVDEKIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCT 294
           P    + +A    EK + +A+ I LE+G  FQIQDD++D FGD   TGK+GTDIQ+ KC+
Sbjct: 275 PIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCS 334

Query: 293 WLAVQALQRCTEAQRTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQ 114
           WL VQ LQR T  Q  + K  YG  E   V R+K LYE+L LP ++   E+  Y +I+  
Sbjct: 335 WLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMAL 394

Query: 113 IENITIEAARVLFKKLLDITYNRQ 42
           IE         +F  L    Y R+
Sbjct: 395 IEQYAAPLPPAVFLGLARKIYKRR 418



 Score = 53.2 bits (122), Expect = 1e-06
 Identities = 29/99 (29%), Positives = 48/99 (48%), Gaps = 1/99 (1%)
 Frame = -2

Query: 762 RGMPCWYRRPEVGITCAFXDSLLIHSSLFEFXXTNFRTNPNYIKMFELFNETLWRTSMGQ 583
           RG  CWY++P VG+  A  D+ L+ + ++       R  P Y+ + ELF ++ ++T +GQ
Sbjct: 179 RGQICWYQKPGVGLD-AINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQ 237

Query: 582 HLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYNLPV 469
            LD +T  +   D   FT  R             + LP+
Sbjct: 238 TLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPI 276


>Z47055-1|CAA87327.1|  348|Homo sapiens farnesyl pyrophosphate
           synthetase like-4 protein.
          Length = 348

 Score =  106 bits (254), Expect = 1e-22
 Identities = 55/132 (41%), Positives = 72/132 (54%)
 Frame = -3

Query: 440 VDEKIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAVQALQRCT 261
           V EK + +A  I LE+G   QIQDD+++ FGD   TGK+GTDIQ+ KC  L VQ L R T
Sbjct: 215 VXEKEHANAXKILLEMGEFSQIQDDYLELFGDPSVTGKIGTDIQDXKCNCLXVQCLXRAT 274

Query: 260 EAQRTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIENITIEAARV 81
             Q  + K  YG  E   V R+K LYE+L LP ++   E+  Y +I+  IE         
Sbjct: 275 PEQYQILKENYGQKEAEKVPRVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPA 334

Query: 80  LFKKLLDITYNR 45
           +F  L    Y R
Sbjct: 335 VFLGLARQIYKR 346



 Score = 53.2 bits (122), Expect = 1e-06
 Identities = 29/99 (29%), Positives = 47/99 (47%), Gaps = 1/99 (1%)
 Frame = -2

Query: 762 RGMPCWYRRPEVGITCAFXDSLLIHSSLFEFXXTNFRTNPNYIKMFELFNETLWRTSMGQ 583
           RG  CWY++P VG+  A  D+ L+ + ++       R  P Y+ + ELF ++ ++T +GQ
Sbjct: 108 RGQICWYQKPGVGLD-AIDDANLLEACIYPLLKLYCREQPYYLNLIELFLQSSYQTEIGQ 166

Query: 582 HLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYNLPV 469
            LD +T  +   D   FT  R               LP+
Sbjct: 167 TLDLLTXPQGNVDLVRFTEKRYISIVKYKTALSSSYLPI 205


>BC050292-1|AAH50292.1|  298|Homo sapiens LOC619190 protein protein.
          Length = 298

 Score =  103 bits (248), Expect = 6e-22
 Identities = 50/122 (40%), Positives = 70/122 (57%)
 Frame = -3

Query: 473 PFXLGLLLAENVDEKIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCT 294
           P    + ++   D+K + SA+ I LEI   FQIQDD++D  GD   TG+VG D Q+ KC+
Sbjct: 177 PVAAAMYMSRMDDKKEHTSAKKILLEIQEFFQIQDDYLDFSGDPSVTGRVGNDFQDNKCS 236

Query: 293 WLAVQALQRCTEAQRTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQ 114
           WL VQ L + T  Q  + K  Y   E   V R+K LYE+L LP ++   EK  Y +++  
Sbjct: 237 WLVVQCLLQATPEQYQILKENYRQKEAEKVARVKALYEELDLPAVFLQYEKDSYSHVMGL 296

Query: 113 IE 108
           IE
Sbjct: 297 IE 298



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 19/66 (28%), Positives = 37/66 (56%)
 Frame = -2

Query: 762 RGMPCWYRRPEVGITCAFXDSLLIHSSLFEFXXTNFRTNPNYIKMFELFNETLWRTSMGQ 583
           +G   WY++  +G+  A  D++L+ + ++       R  P Y+ + ELF +  ++T +GQ
Sbjct: 81  QGQISWYQKLGMGLD-AINDAILLEACIYCLLKLYCREQPYYLNLMELFQQNSYQTEIGQ 139

Query: 582 HLDHVT 565
            LD +T
Sbjct: 140 TLDLIT 145


>M87434-1|AAA60607.1|  727|Homo sapiens 71 kDa 2'5' oligoadenylate
           synthetase protein.
          Length = 727

 Score = 30.3 bits (65), Expect = 8.3
 Identities = 12/31 (38%), Positives = 20/31 (64%)
 Frame = -1

Query: 325 LVQIYKSANVLGWQFKRCSAVLKHNVQYSKP 233
           L+ +YKS+++ G +F  C  VL+ N   S+P
Sbjct: 506 LIDLYKSSDLPGGEFSTCFTVLQRNFIRSRP 536


>M87284-1|AAA60606.1|  687|Homo sapiens 2'5' oligoadenylate
           synthetase protein.
          Length = 687

 Score = 30.3 bits (65), Expect = 8.3
 Identities = 12/31 (38%), Positives = 20/31 (64%)
 Frame = -1

Query: 325 LVQIYKSANVLGWQFKRCSAVLKHNVQYSKP 233
           L+ +YKS+++ G +F  C  VL+ N   S+P
Sbjct: 506 LIDLYKSSDLPGGEFSTCFTVLQRNFIRSRP 536


>BC049215-1|AAH49215.1|  687|Homo sapiens 2'-5'-oligoadenylate
           synthetase 2, 69/71kDa protein.
          Length = 687

 Score = 30.3 bits (65), Expect = 8.3
 Identities = 12/31 (38%), Positives = 20/31 (64%)
 Frame = -1

Query: 325 LVQIYKSANVLGWQFKRCSAVLKHNVQYSKP 233
           L+ +YKS+++ G +F  C  VL+ N   S+P
Sbjct: 506 LIDLYKSSDLPGGEFSTCFTVLQRNFIRSRP 536


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 112,157,817
Number of Sequences: 237096
Number of extensions: 2250269
Number of successful extensions: 4382
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4246
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4376
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9701808132
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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