Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P01_F_O07
(688 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M60258-1|AAA36596.1| 526|Homo sapiens cerebroside sulfate activ... 67 5e-11
M60257-1|AAA36595.1| 524|Homo sapiens cerebroside sulfate activ... 67 5e-11
M60255-1|AAA36594.1| 527|Homo sapiens cerebroside sulfate activ... 67 5e-11
M32221-1|AAA60303.1| 524|Homo sapiens PSAP protein. 67 5e-11
J03077-1|AAA52560.1| 524|Homo sapiens GLBA protein. 67 5e-11
J03015-1|AAB59494.1| 524|Homo sapiens sphingolipid activator pr... 67 5e-11
D00422-1|BAA00321.1| 527|Homo sapiens sphingolipid activator pr... 67 5e-11
CR456746-1|CAG33027.1| 524|Homo sapiens PSAP protein. 67 5e-11
BT006849-1|AAP35495.1| 524|Homo sapiens prosaposin (variant Gau... 67 5e-11
BC007612-1|AAH07612.1| 524|Homo sapiens prosaposin (variant Gau... 67 5e-11
BC004275-1|AAH04275.1| 524|Homo sapiens prosaposin (variant Gau... 67 5e-11
BC001503-1|AAH01503.1| 524|Homo sapiens prosaposin (variant Gau... 67 5e-11
AL731541-2|CAI40837.1| 524|Homo sapiens prosaposin (variant Gau... 67 5e-11
AL731541-1|CAI40836.1| 559|Homo sapiens prosaposin (variant Gau... 67 5e-11
AK223290-1|BAD97010.1| 524|Homo sapiens prosaposin (variant Gau... 67 5e-11
AB209776-1|BAD93013.1| 530|Homo sapiens prosaposin variant prot... 67 5e-11
J02761-1|AAA60212.1| 381|Homo sapiens pulmonary surfactant-asso... 57 7e-08
BC032785-1|AAH32785.1| 381|Homo sapiens surfactant, pulmonary-a... 57 7e-08
DQ991252-1|ABJ55983.1| 521|Homo sapiens prosaposin-like protein... 56 2e-07
DQ317589-1|ABC59511.1| 147|Homo sapiens truncated surfactant pu... 56 2e-07
BC068579-1|AAH68579.1| 543|Homo sapiens PSAPL1 protein protein. 56 2e-07
M24461-1|AAB59541.1| 381|Homo sapiens pulmonary surfactant-asso... 54 4e-07
AF400074-1|AAK77913.1| 381|Homo sapiens surfactant, pulmonary-a... 54 4e-07
BC091483-1|AAH91483.1| 240|Homo sapiens PSAP protein protein. 53 1e-06
Y09788-1|CAA70926.1| 845|Homo sapiens mucin protein. 36 0.10
U95031-1|AAB65151.1| 879|Homo sapiens sublingual gland mucin pr... 36 0.10
U78551-1|AAC51343.1| 390|Homo sapiens mucin MUC5B protein. 36 0.10
AK097698-1|BAC05143.1| 241|Homo sapiens protein ( Homo sapiens ... 34 0.41
BC032638-1|AAH32638.1| 411|Homo sapiens methyl-CpG binding doma... 31 5.1
AF120993-1|AAD56597.1| 411|Homo sapiens methyl-CpG binding prot... 31 5.1
AF072242-1|AAC68871.1| 411|Homo sapiens methyl-CpG binding prot... 31 5.1
AF039701-1|AAC18050.1| 200|Homo sapiens antigen NY-CO-41 protein. 31 5.1
AF111162-1|AAD43651.1| 1849|Homo sapiens guanine nucleotide exch... 30 6.7
AF084520-1|AAD38427.1| 1849|Homo sapiens brefeldin A-inhibited g... 30 6.7
AB209324-1|BAD92561.1| 1278|Homo sapiens brefeldin A-inhibited g... 30 6.7
BC050449-1|AAH50449.1| 832|Homo sapiens ARFGEF2 protein protein. 30 8.9
AL121903-1|CAI19614.1| 1785|Homo sapiens ADP-ribosylation factor... 30 8.9
AL049537-1|CAI19320.1| 1785|Homo sapiens ADP-ribosylation factor... 30 8.9
AK126902-1|BAC86743.1| 247|Homo sapiens protein ( Homo sapiens ... 30 8.9
AK090647-1|BAC03496.1| 353|Homo sapiens protein. 30 8.9
AF084521-1|AAD38428.1| 1785|Homo sapiens brefeldin A-inhibited g... 30 8.9
>M60258-1|AAA36596.1| 526|Homo sapiens cerebroside sulfate
activator protein protein.
Length = 526
Score = 67.3 bits (157), Expect = 5e-11
Identities = 34/122 (27%), Positives = 58/122 (47%), Gaps = 1/122 (0%)
Frame = +2
Query: 245 KECAKGPQVWCESLKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDL 424
KEC +G VWC+++K ++CGAV HC TVW K +I V + +KD
Sbjct: 23 KECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDN 80
Query: 425 INEEYLAASIESACHDIQYPAIAKICKDNTAHFENYIHHVLKSNTSAE-TMCKIVGMCNN 601
EE + +E C + P ++ CK+ + I ++K S +C + +C +
Sbjct: 81 ATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSALNLCES 140
Query: 602 MK 607
++
Sbjct: 141 LQ 142
Score = 40.3 bits (90), Expect = 0.006
Identities = 13/31 (41%), Positives = 19/31 (61%)
Frame = +2
Query: 245 KECAKGPQVWCESLKRGAECGAVGHCTATVW 337
++C GP WC++ + A+C AV HC VW
Sbjct: 495 EKCIWGPSYWCQNTETAAQCNAVEHCKRHVW 525
>M60257-1|AAA36595.1| 524|Homo sapiens cerebroside sulfate
activator protein protein.
Length = 524
Score = 67.3 bits (157), Expect = 5e-11
Identities = 34/122 (27%), Positives = 58/122 (47%), Gaps = 1/122 (0%)
Frame = +2
Query: 245 KECAKGPQVWCESLKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDL 424
KEC +G VWC+++K ++CGAV HC TVW K +I V + +KD
Sbjct: 23 KECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDN 80
Query: 425 INEEYLAASIESACHDIQYPAIAKICKDNTAHFENYIHHVLKSNTSAE-TMCKIVGMCNN 601
EE + +E C + P ++ CK+ + I ++K S +C + +C +
Sbjct: 81 ATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSALNLCES 140
Query: 602 MK 607
++
Sbjct: 141 LQ 142
Score = 40.3 bits (90), Expect = 0.006
Identities = 13/31 (41%), Positives = 19/31 (61%)
Frame = +2
Query: 245 KECAKGPQVWCESLKRGAECGAVGHCTATVW 337
++C GP WC++ + A+C AV HC VW
Sbjct: 493 EKCIWGPSYWCQNTETAAQCNAVEHCKRHVW 523
>M60255-1|AAA36594.1| 527|Homo sapiens cerebroside sulfate
activator protein protein.
Length = 527
Score = 67.3 bits (157), Expect = 5e-11
Identities = 34/122 (27%), Positives = 58/122 (47%), Gaps = 1/122 (0%)
Frame = +2
Query: 245 KECAKGPQVWCESLKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDL 424
KEC +G VWC+++K ++CGAV HC TVW K +I V + +KD
Sbjct: 23 KECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDN 80
Query: 425 INEEYLAASIESACHDIQYPAIAKICKDNTAHFENYIHHVLKSNTSAE-TMCKIVGMCNN 601
EE + +E C + P ++ CK+ + I ++K S +C + +C +
Sbjct: 81 ATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSALNLCES 140
Query: 602 MK 607
++
Sbjct: 141 LQ 142
Score = 40.3 bits (90), Expect = 0.006
Identities = 13/31 (41%), Positives = 19/31 (61%)
Frame = +2
Query: 245 KECAKGPQVWCESLKRGAECGAVGHCTATVW 337
++C GP WC++ + A+C AV HC VW
Sbjct: 496 EKCIWGPSYWCQNTETAAQCNAVEHCKRHVW 526
>M32221-1|AAA60303.1| 524|Homo sapiens PSAP protein.
Length = 524
Score = 67.3 bits (157), Expect = 5e-11
Identities = 34/122 (27%), Positives = 58/122 (47%), Gaps = 1/122 (0%)
Frame = +2
Query: 245 KECAKGPQVWCESLKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDL 424
KEC +G VWC+++K ++CGAV HC TVW K +I V + +KD
Sbjct: 23 KECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDN 80
Query: 425 INEEYLAASIESACHDIQYPAIAKICKDNTAHFENYIHHVLKSNTSAE-TMCKIVGMCNN 601
EE + +E C + P ++ CK+ + I ++K S +C + +C +
Sbjct: 81 ATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSALNLCES 140
Query: 602 MK 607
++
Sbjct: 141 LQ 142
Score = 40.3 bits (90), Expect = 0.006
Identities = 13/31 (41%), Positives = 19/31 (61%)
Frame = +2
Query: 245 KECAKGPQVWCESLKRGAECGAVGHCTATVW 337
++C GP WC++ + A+C AV HC VW
Sbjct: 493 EKCIWGPSYWCQNTETAAQCNAVEHCKRHVW 523
>J03077-1|AAA52560.1| 524|Homo sapiens GLBA protein.
Length = 524
Score = 67.3 bits (157), Expect = 5e-11
Identities = 34/122 (27%), Positives = 58/122 (47%), Gaps = 1/122 (0%)
Frame = +2
Query: 245 KECAKGPQVWCESLKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDL 424
KEC +G VWC+++K ++CGAV HC TVW K +I V + +KD
Sbjct: 23 KECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDN 80
Query: 425 INEEYLAASIESACHDIQYPAIAKICKDNTAHFENYIHHVLKSNTSAE-TMCKIVGMCNN 601
EE + +E C + P ++ CK+ + I ++K S +C + +C +
Sbjct: 81 ATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSALNLCES 140
Query: 602 MK 607
++
Sbjct: 141 LQ 142
Score = 40.3 bits (90), Expect = 0.006
Identities = 13/31 (41%), Positives = 19/31 (61%)
Frame = +2
Query: 245 KECAKGPQVWCESLKRGAECGAVGHCTATVW 337
++C GP WC++ + A+C AV HC VW
Sbjct: 493 EKCIWGPSYWCQNTETAAQCNAVEHCKRHVW 523
>J03015-1|AAB59494.1| 524|Homo sapiens sphingolipid activator
precursor protein.
Length = 524
Score = 67.3 bits (157), Expect = 5e-11
Identities = 34/122 (27%), Positives = 58/122 (47%), Gaps = 1/122 (0%)
Frame = +2
Query: 245 KECAKGPQVWCESLKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDL 424
KEC +G VWC+++K ++CGAV HC TVW K +I V + +KD
Sbjct: 23 KECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDN 80
Query: 425 INEEYLAASIESACHDIQYPAIAKICKDNTAHFENYIHHVLKSNTSAE-TMCKIVGMCNN 601
EE + +E C + P ++ CK+ + I ++K S +C + +C +
Sbjct: 81 ATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSALNLCES 140
Query: 602 MK 607
++
Sbjct: 141 LQ 142
Score = 40.3 bits (90), Expect = 0.006
Identities = 13/31 (41%), Positives = 19/31 (61%)
Frame = +2
Query: 245 KECAKGPQVWCESLKRGAECGAVGHCTATVW 337
++C GP WC++ + A+C AV HC VW
Sbjct: 493 EKCIWGPSYWCQNTETAAQCNAVEHCKRHVW 523
>D00422-1|BAA00321.1| 527|Homo sapiens sphingolipid activator
proteins protein.
Length = 527
Score = 67.3 bits (157), Expect = 5e-11
Identities = 34/122 (27%), Positives = 58/122 (47%), Gaps = 1/122 (0%)
Frame = +2
Query: 245 KECAKGPQVWCESLKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDL 424
KEC +G VWC+++K ++CGAV HC TVW K +I V + +KD
Sbjct: 23 KECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDN 80
Query: 425 INEEYLAASIESACHDIQYPAIAKICKDNTAHFENYIHHVLKSNTSAE-TMCKIVGMCNN 601
EE + +E C + P ++ CK+ + I ++K S +C + +C +
Sbjct: 81 ATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSALNLCES 140
Query: 602 MK 607
++
Sbjct: 141 LQ 142
Score = 40.3 bits (90), Expect = 0.006
Identities = 13/31 (41%), Positives = 19/31 (61%)
Frame = +2
Query: 245 KECAKGPQVWCESLKRGAECGAVGHCTATVW 337
++C GP WC++ + A+C AV HC VW
Sbjct: 496 EKCIWGPSYWCQNTETAAQCNAVEHCKRHVW 526
>CR456746-1|CAG33027.1| 524|Homo sapiens PSAP protein.
Length = 524
Score = 67.3 bits (157), Expect = 5e-11
Identities = 34/122 (27%), Positives = 58/122 (47%), Gaps = 1/122 (0%)
Frame = +2
Query: 245 KECAKGPQVWCESLKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDL 424
KEC +G VWC+++K ++CGAV HC TVW K +I V + +KD
Sbjct: 23 KECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDN 80
Query: 425 INEEYLAASIESACHDIQYPAIAKICKDNTAHFENYIHHVLKSNTSAE-TMCKIVGMCNN 601
EE + +E C + P ++ CK+ + I ++K S +C + +C +
Sbjct: 81 ATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSALNLCES 140
Query: 602 MK 607
++
Sbjct: 141 LQ 142
Score = 40.3 bits (90), Expect = 0.006
Identities = 13/31 (41%), Positives = 19/31 (61%)
Frame = +2
Query: 245 KECAKGPQVWCESLKRGAECGAVGHCTATVW 337
++C GP WC++ + A+C AV HC VW
Sbjct: 493 EKCIWGPSYWCQNTETAAQCNAVEHCKRHVW 523
>BT006849-1|AAP35495.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 67.3 bits (157), Expect = 5e-11
Identities = 34/122 (27%), Positives = 58/122 (47%), Gaps = 1/122 (0%)
Frame = +2
Query: 245 KECAKGPQVWCESLKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDL 424
KEC +G VWC+++K ++CGAV HC TVW K +I V + +KD
Sbjct: 23 KECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDN 80
Query: 425 INEEYLAASIESACHDIQYPAIAKICKDNTAHFENYIHHVLKSNTSAE-TMCKIVGMCNN 601
EE + +E C + P ++ CK+ + I ++K S +C + +C +
Sbjct: 81 ATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSALNLCES 140
Query: 602 MK 607
++
Sbjct: 141 LQ 142
Score = 40.3 bits (90), Expect = 0.006
Identities = 13/31 (41%), Positives = 19/31 (61%)
Frame = +2
Query: 245 KECAKGPQVWCESLKRGAECGAVGHCTATVW 337
++C GP WC++ + A+C AV HC VW
Sbjct: 493 EKCIWGPSYWCQNTETAAQCNAVEHCKRHVW 523
>BC007612-1|AAH07612.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 67.3 bits (157), Expect = 5e-11
Identities = 34/122 (27%), Positives = 58/122 (47%), Gaps = 1/122 (0%)
Frame = +2
Query: 245 KECAKGPQVWCESLKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDL 424
KEC +G VWC+++K ++CGAV HC TVW K +I V + +KD
Sbjct: 23 KECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDN 80
Query: 425 INEEYLAASIESACHDIQYPAIAKICKDNTAHFENYIHHVLKSNTSAE-TMCKIVGMCNN 601
EE + +E C + P ++ CK+ + I ++K S +C + +C +
Sbjct: 81 ATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSALNLCES 140
Query: 602 MK 607
++
Sbjct: 141 LQ 142
Score = 40.3 bits (90), Expect = 0.006
Identities = 13/31 (41%), Positives = 19/31 (61%)
Frame = +2
Query: 245 KECAKGPQVWCESLKRGAECGAVGHCTATVW 337
++C GP WC++ + A+C AV HC VW
Sbjct: 493 EKCIWGPSYWCQNTETAAQCNAVEHCKRHVW 523
>BC004275-1|AAH04275.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 67.3 bits (157), Expect = 5e-11
Identities = 34/122 (27%), Positives = 58/122 (47%), Gaps = 1/122 (0%)
Frame = +2
Query: 245 KECAKGPQVWCESLKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDL 424
KEC +G VWC+++K ++CGAV HC TVW K +I V + +KD
Sbjct: 23 KECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDN 80
Query: 425 INEEYLAASIESACHDIQYPAIAKICKDNTAHFENYIHHVLKSNTSAE-TMCKIVGMCNN 601
EE + +E C + P ++ CK+ + I ++K S +C + +C +
Sbjct: 81 ATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSALNLCES 140
Query: 602 MK 607
++
Sbjct: 141 LQ 142
Score = 40.3 bits (90), Expect = 0.006
Identities = 13/31 (41%), Positives = 19/31 (61%)
Frame = +2
Query: 245 KECAKGPQVWCESLKRGAECGAVGHCTATVW 337
++C GP WC++ + A+C AV HC VW
Sbjct: 493 EKCIWGPSYWCQNTETAAQCNAVEHCKRHVW 523
>BC001503-1|AAH01503.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 67.3 bits (157), Expect = 5e-11
Identities = 34/122 (27%), Positives = 58/122 (47%), Gaps = 1/122 (0%)
Frame = +2
Query: 245 KECAKGPQVWCESLKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDL 424
KEC +G VWC+++K ++CGAV HC TVW K +I V + +KD
Sbjct: 23 KECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDN 80
Query: 425 INEEYLAASIESACHDIQYPAIAKICKDNTAHFENYIHHVLKSNTSAE-TMCKIVGMCNN 601
EE + +E C + P ++ CK+ + I ++K S +C + +C +
Sbjct: 81 ATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSALNLCES 140
Query: 602 MK 607
++
Sbjct: 141 LQ 142
Score = 40.3 bits (90), Expect = 0.006
Identities = 13/31 (41%), Positives = 19/31 (61%)
Frame = +2
Query: 245 KECAKGPQVWCESLKRGAECGAVGHCTATVW 337
++C GP WC++ + A+C AV HC VW
Sbjct: 493 EKCIWGPSYWCQNTETAAQCNAVEHCKRHVW 523
>AL731541-2|CAI40837.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 67.3 bits (157), Expect = 5e-11
Identities = 34/122 (27%), Positives = 58/122 (47%), Gaps = 1/122 (0%)
Frame = +2
Query: 245 KECAKGPQVWCESLKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDL 424
KEC +G VWC+++K ++CGAV HC TVW K +I V + +KD
Sbjct: 23 KECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDN 80
Query: 425 INEEYLAASIESACHDIQYPAIAKICKDNTAHFENYIHHVLKSNTSAE-TMCKIVGMCNN 601
EE + +E C + P ++ CK+ + I ++K S +C + +C +
Sbjct: 81 ATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSALNLCES 140
Query: 602 MK 607
++
Sbjct: 141 LQ 142
Score = 40.3 bits (90), Expect = 0.006
Identities = 13/31 (41%), Positives = 19/31 (61%)
Frame = +2
Query: 245 KECAKGPQVWCESLKRGAECGAVGHCTATVW 337
++C GP WC++ + A+C AV HC VW
Sbjct: 493 EKCIWGPSYWCQNTETAAQCNAVEHCKRHVW 523
>AL731541-1|CAI40836.1| 559|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 559
Score = 67.3 bits (157), Expect = 5e-11
Identities = 34/122 (27%), Positives = 58/122 (47%), Gaps = 1/122 (0%)
Frame = +2
Query: 245 KECAKGPQVWCESLKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDL 424
KEC +G VWC+++K ++CGAV HC TVW K +I V + +KD
Sbjct: 23 KECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDN 80
Query: 425 INEEYLAASIESACHDIQYPAIAKICKDNTAHFENYIHHVLKSNTSAE-TMCKIVGMCNN 601
EE + +E C + P ++ CK+ + I ++K S +C + +C +
Sbjct: 81 ATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSALNLCES 140
Query: 602 MK 607
++
Sbjct: 141 LQ 142
Score = 40.3 bits (90), Expect = 0.006
Identities = 13/31 (41%), Positives = 19/31 (61%)
Frame = +2
Query: 245 KECAKGPQVWCESLKRGAECGAVGHCTATVW 337
++C GP WC++ + A+C AV HC VW
Sbjct: 493 EKCIWGPSYWCQNTETAAQCNAVEHCKRHVW 523
>AK223290-1|BAD97010.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) v protein.
Length = 524
Score = 67.3 bits (157), Expect = 5e-11
Identities = 34/122 (27%), Positives = 58/122 (47%), Gaps = 1/122 (0%)
Frame = +2
Query: 245 KECAKGPQVWCESLKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDL 424
KEC +G VWC+++K ++CGAV HC TVW K +I V + +KD
Sbjct: 23 KECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDN 80
Query: 425 INEEYLAASIESACHDIQYPAIAKICKDNTAHFENYIHHVLKSNTSAE-TMCKIVGMCNN 601
EE + +E C + P ++ CK+ + I ++K S +C + +C +
Sbjct: 81 ATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSALNLCES 140
Query: 602 MK 607
++
Sbjct: 141 LQ 142
Score = 40.3 bits (90), Expect = 0.006
Identities = 13/31 (41%), Positives = 19/31 (61%)
Frame = +2
Query: 245 KECAKGPQVWCESLKRGAECGAVGHCTATVW 337
++C GP WC++ + A+C AV HC VW
Sbjct: 493 EKCIWGPSYWCQNTETAAQCNAVEHCKRHVW 523
>AB209776-1|BAD93013.1| 530|Homo sapiens prosaposin variant
protein.
Length = 530
Score = 67.3 bits (157), Expect = 5e-11
Identities = 34/122 (27%), Positives = 58/122 (47%), Gaps = 1/122 (0%)
Frame = +2
Query: 245 KECAKGPQVWCESLKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDL 424
KEC +G VWC+++K ++CGAV HC TVW K +I V + +KD
Sbjct: 26 KECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDN 83
Query: 425 INEEYLAASIESACHDIQYPAIAKICKDNTAHFENYIHHVLKSNTSAE-TMCKIVGMCNN 601
EE + +E C + P ++ CK+ + I ++K S +C + +C +
Sbjct: 84 ATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSALNLCES 143
Query: 602 MK 607
++
Sbjct: 144 LQ 145
Score = 40.3 bits (90), Expect = 0.006
Identities = 13/31 (41%), Positives = 19/31 (61%)
Frame = +2
Query: 245 KECAKGPQVWCESLKRGAECGAVGHCTATVW 337
++C GP WC++ + A+C AV HC VW
Sbjct: 499 EKCIWGPSYWCQNTETAAQCNAVEHCKRHVW 529
>J02761-1|AAA60212.1| 381|Homo sapiens pulmonary
surfactant-associated protein SP-B protein.
Length = 381
Score = 56.8 bits (131), Expect = 7e-08
Identities = 33/138 (23%), Positives = 59/138 (42%)
Frame = +2
Query: 188 LLSLTFLCCTNLSFARQVPKECAKGPQVWCESLKRGAECGAVGHCTATVWEKQKPDVSDN 367
LL L LC + CA+GP+ WC+SL++ +C A+GHC VW D
Sbjct: 11 LLLLPTLCGPGTAAWTTSSLACAQGPEFWCQSLEQALQCRALGHCLQEVWGHVGADDLCQ 70
Query: 368 EISSKFVKLFRGLKDVKDLINEEYLAASIESACHDIQYPAIAKICKDNTAHFENYIHHVL 547
E V + K K+ I ++ + +E C+ + + C + +
Sbjct: 71 ECED-IVHILN--KMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFPLVIDYF 127
Query: 548 KSNTSAETMCKIVGMCNN 601
++ T + +C +G+C +
Sbjct: 128 QNQTDSNGICMHLGLCKS 145
>BC032785-1|AAH32785.1| 381|Homo sapiens surfactant,
pulmonary-associated protein B protein.
Length = 381
Score = 56.8 bits (131), Expect = 7e-08
Identities = 33/138 (23%), Positives = 59/138 (42%)
Frame = +2
Query: 188 LLSLTFLCCTNLSFARQVPKECAKGPQVWCESLKRGAECGAVGHCTATVWEKQKPDVSDN 367
LL L LC + CA+GP+ WC+SL++ +C A+GHC VW D
Sbjct: 11 LLLLPTLCGPGTAAWTTSSLACAQGPEFWCQSLEQALQCRALGHCLQEVWGHVGADDLCQ 70
Query: 368 EISSKFVKLFRGLKDVKDLINEEYLAASIESACHDIQYPAIAKICKDNTAHFENYIHHVL 547
E V + K K+ I ++ + +E C+ + + C + +
Sbjct: 71 ECED-IVHILN--KMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFPLVIDYF 127
Query: 548 KSNTSAETMCKIVGMCNN 601
++ T + +C +G+C +
Sbjct: 128 QNQTDSNGICMHLGLCKS 145
>DQ991252-1|ABJ55983.1| 521|Homo sapiens prosaposin-like protein 1
protein.
Length = 521
Score = 55.6 bits (128), Expect = 2e-07
Identities = 20/34 (58%), Positives = 24/34 (70%)
Frame = +2
Query: 242 PKECAKGPQVWCESLKRGAECGAVGHCTATVWEK 343
P+ECAKG VWC+ L+ A CGAVG+C VW K
Sbjct: 23 PQECAKGSTVWCQDLQTAARCGAVGYCQGAVWNK 56
Score = 39.5 bits (88), Expect = 0.011
Identities = 14/32 (43%), Positives = 18/32 (56%)
Frame = +2
Query: 248 ECAKGPQVWCESLKRGAECGAVGHCTATVWEK 343
+CA GP WC S + C AV HC VW++
Sbjct: 481 QCALGPSFWCRSQEAAKLCNAVQHCQKHVWKE 512
>DQ317589-1|ABC59511.1| 147|Homo sapiens truncated surfactant
pulmonary-associated protein B protein.
Length = 147
Score = 55.6 bits (128), Expect = 2e-07
Identities = 32/138 (23%), Positives = 59/138 (42%)
Frame = +2
Query: 188 LLSLTFLCCTNLSFARQVPKECAKGPQVWCESLKRGAECGAVGHCTATVWEKQKPDVSDN 367
LL L LC + CA+GP+ WC+SL++ +C A+GHC VW D
Sbjct: 7 LLLLPTLCGPGTAAWTTSSLACAQGPEFWCQSLEQALQCRALGHCLQEVWGHVGADDLCQ 66
Query: 368 EISSKFVKLFRGLKDVKDLINEEYLAASIESACHDIQYPAIAKICKDNTAHFENYIHHVL 547
E V + K K+ I ++ + +E C+ + + C + +
Sbjct: 67 ECED-IVHILN--KMAKEAIFQDTMREFLEQECNVLPLKLLMPQCNQVLDDYFPLVIDYF 123
Query: 548 KSNTSAETMCKIVGMCNN 601
++ + ++C +G+C +
Sbjct: 124 QNQIDSNSICMHLGLCKS 141
>BC068579-1|AAH68579.1| 543|Homo sapiens PSAPL1 protein protein.
Length = 543
Score = 55.6 bits (128), Expect = 2e-07
Identities = 20/34 (58%), Positives = 24/34 (70%)
Frame = +2
Query: 242 PKECAKGPQVWCESLKRGAECGAVGHCTATVWEK 343
P+ECAKG VWC+ L+ A CGAVG+C VW K
Sbjct: 45 PQECAKGSTVWCQDLQTAARCGAVGYCQGAVWNK 78
Score = 39.5 bits (88), Expect = 0.011
Identities = 14/32 (43%), Positives = 18/32 (56%)
Frame = +2
Query: 248 ECAKGPQVWCESLKRGAECGAVGHCTATVWEK 343
+CA GP WC S + C AV HC VW++
Sbjct: 503 QCALGPSFWCRSQEAAKLCNAVQHCQKHVWKE 534
>M24461-1|AAB59541.1| 381|Homo sapiens pulmonary
surfactant-associated protein SP-B protein.
Length = 381
Score = 54.4 bits (125), Expect = 4e-07
Identities = 32/138 (23%), Positives = 58/138 (42%)
Frame = +2
Query: 188 LLSLTFLCCTNLSFARQVPKECAKGPQVWCESLKRGAECGAVGHCTATVWEKQKPDVSDN 367
LL L LC + CA+GP+ WC+SL++ +C A+GHC VW D
Sbjct: 11 LLLLPTLCGPGTAAWTTSSLACAQGPEFWCQSLEQALQCRALGHCLQEVWGHVGADDLCQ 70
Query: 368 EISSKFVKLFRGLKDVKDLINEEYLAASIESACHDIQYPAIAKICKDNTAHFENYIHHVL 547
E V + K K+ I ++ + +E C+ + + C + +
Sbjct: 71 ECED-IVHILN--KMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFPLVIDYF 127
Query: 548 KSNTSAETMCKIVGMCNN 601
++ + +C +G+C +
Sbjct: 128 QNQIDSNGICMHLGLCKS 145
>AF400074-1|AAK77913.1| 381|Homo sapiens surfactant,
pulmonary-associated protein B protein.
Length = 381
Score = 54.4 bits (125), Expect = 4e-07
Identities = 32/138 (23%), Positives = 58/138 (42%)
Frame = +2
Query: 188 LLSLTFLCCTNLSFARQVPKECAKGPQVWCESLKRGAECGAVGHCTATVWEKQKPDVSDN 367
LL L LC + CA+GP+ WC+SL++ +C A+GHC VW D
Sbjct: 11 LLLLPTLCGPGTAAWTTSSLACAQGPEFWCQSLEQALQCRALGHCLQEVWGHVGADDLCQ 70
Query: 368 EISSKFVKLFRGLKDVKDLINEEYLAASIESACHDIQYPAIAKICKDNTAHFENYIHHVL 547
E V + K K+ I ++ + +E C+ + + C + +
Sbjct: 71 ECED-IVHILN--KMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFPLVIDYF 127
Query: 548 KSNTSAETMCKIVGMCNN 601
++ + +C +G+C +
Sbjct: 128 QNQIDSNGICMHLGLCKS 145
>BC091483-1|AAH91483.1| 240|Homo sapiens PSAP protein protein.
Length = 240
Score = 52.8 bits (121), Expect = 1e-06
Identities = 18/33 (54%), Positives = 24/33 (72%)
Frame = +2
Query: 245 KECAKGPQVWCESLKRGAECGAVGHCTATVWEK 343
KEC +G VWC+++K ++CGAV HC TVW K
Sbjct: 23 KECTRGSAVWCQNVKTASDCGAVKHCLQTVWNK 55
Score = 40.3 bits (90), Expect = 0.006
Identities = 13/31 (41%), Positives = 19/31 (61%)
Frame = +2
Query: 245 KECAKGPQVWCESLKRGAECGAVGHCTATVW 337
++C GP WC++ + A+C AV HC VW
Sbjct: 209 EKCIWGPSYWCQNTETAAQCNAVEHCKRHVW 239
>Y09788-1|CAA70926.1| 845|Homo sapiens mucin protein.
Length = 845
Score = 36.3 bits (80), Expect = 0.10
Identities = 16/51 (31%), Positives = 20/51 (39%)
Frame = -3
Query: 614 CPISCCYTCRRFCTLSRPMCSI*ERDVCNFRNGPCCLCISSRSQDTGYRGT 462
CP + C C S P+C + +C G CC R Q Y GT
Sbjct: 561 CPETVCVCNTTTCPQSLPVCPPGQESICTQEEGDCCPTFRCRPQLCSYNGT 611
>U95031-1|AAB65151.1| 879|Homo sapiens sublingual gland mucin
protein.
Length = 879
Score = 36.3 bits (80), Expect = 0.10
Identities = 16/51 (31%), Positives = 20/51 (39%)
Frame = -3
Query: 614 CPISCCYTCRRFCTLSRPMCSI*ERDVCNFRNGPCCLCISSRSQDTGYRGT 462
CP + C C S P+C + +C G CC R Q Y GT
Sbjct: 611 CPETVCVCNTTTCPQSLPVCPPGQESICTQEEGDCCPTFRCRPQLCSYNGT 661
>U78551-1|AAC51343.1| 390|Homo sapiens mucin MUC5B protein.
Length = 390
Score = 36.3 bits (80), Expect = 0.10
Identities = 16/51 (31%), Positives = 20/51 (39%)
Frame = -3
Query: 614 CPISCCYTCRRFCTLSRPMCSI*ERDVCNFRNGPCCLCISSRSQDTGYRGT 462
CP + C C S P+C + +C G CC R Q Y GT
Sbjct: 106 CPETVCVCNTTTCPQSLPVCPPGQESICTQEEGDCCPTFRCRPQLCSYNGT 156
>AK097698-1|BAC05143.1| 241|Homo sapiens protein ( Homo sapiens
cDNA FLJ40379 fis, clone TESTI2035262, weakly similar to
PROACTIVATOR POLYPEPTIDE PRECURSOR. ).
Length = 241
Score = 34.3 bits (75), Expect = 0.41
Identities = 12/25 (48%), Positives = 14/25 (56%)
Frame = +2
Query: 248 ECAKGPQVWCESLKRGAECGAVGHC 322
+CA GP WC S + C AV HC
Sbjct: 213 QCALGPSFWCRSQEAAKLCNAVQHC 237
>BC032638-1|AAH32638.1| 411|Homo sapiens methyl-CpG binding domain
protein 2 protein.
Length = 411
Score = 30.7 bits (66), Expect = 5.1
Identities = 16/58 (27%), Positives = 32/58 (55%), Gaps = 3/58 (5%)
Frame = +2
Query: 335 WEKQKPDVSDNEISSKFVK---LFRGLKDVKDLINEEYLAASIESACHDIQYPAIAKI 499
WEK+ +S ++++ + +K L +GL+ V N+E L +++ SA H P ++
Sbjct: 283 WEKRLQGLSASDVTEQIIKTMELPKGLQGVGPGSNDETLLSAVASALHTSSAPITGQV 340
>AF120993-1|AAD56597.1| 411|Homo sapiens methyl-CpG binding protein
2 protein.
Length = 411
Score = 30.7 bits (66), Expect = 5.1
Identities = 16/58 (27%), Positives = 32/58 (55%), Gaps = 3/58 (5%)
Frame = +2
Query: 335 WEKQKPDVSDNEISSKFVK---LFRGLKDVKDLINEEYLAASIESACHDIQYPAIAKI 499
WEK+ +S ++++ + +K L +GL+ V N+E L +++ SA H P ++
Sbjct: 283 WEKRLQGLSASDVTEQIIKTMELPKGLQGVGPGSNDETLLSAVASALHTSSAPITGQV 340
>AF072242-1|AAC68871.1| 411|Homo sapiens methyl-CpG binding protein
MBD2 protein.
Length = 411
Score = 30.7 bits (66), Expect = 5.1
Identities = 16/58 (27%), Positives = 32/58 (55%), Gaps = 3/58 (5%)
Frame = +2
Query: 335 WEKQKPDVSDNEISSKFVK---LFRGLKDVKDLINEEYLAASIESACHDIQYPAIAKI 499
WEK+ +S ++++ + +K L +GL+ V N+E L +++ SA H P ++
Sbjct: 283 WEKRLQGLSASDVTEQIIKTMELPKGLQGVGPGSNDETLLSAVASALHTSSAPITGQV 340
>AF039701-1|AAC18050.1| 200|Homo sapiens antigen NY-CO-41 protein.
Length = 200
Score = 30.7 bits (66), Expect = 5.1
Identities = 16/58 (27%), Positives = 32/58 (55%), Gaps = 3/58 (5%)
Frame = +2
Query: 335 WEKQKPDVSDNEISSKFVK---LFRGLKDVKDLINEEYLAASIESACHDIQYPAIAKI 499
WEK+ +S ++++ + +K L +GL+ V N+E L +++ SA H P ++
Sbjct: 72 WEKRLQGLSASDVTEQIIKTMELPKGLQGVGPGSNDETLLSAVASALHTSSAPITGQV 129
>AF111162-1|AAD43651.1| 1849|Homo sapiens guanine nucleotide
exchange factor protein.
Length = 1849
Score = 30.3 bits (65), Expect = 6.7
Identities = 14/33 (42%), Positives = 21/33 (63%)
Frame = +2
Query: 350 PDVSDNEISSKFVKLFRGLKDVKDLINEEYLAA 448
P V + +++K+ RG+ D KDL EEYL+A
Sbjct: 841 PQVKNKMTKEQYIKMNRGINDSKDL-PEEYLSA 872
>AF084520-1|AAD38427.1| 1849|Homo sapiens brefeldin A-inhibited
guanine nucleotide-exchange protein 1 protein.
Length = 1849
Score = 30.3 bits (65), Expect = 6.7
Identities = 14/33 (42%), Positives = 21/33 (63%)
Frame = +2
Query: 350 PDVSDNEISSKFVKLFRGLKDVKDLINEEYLAA 448
P V + +++K+ RG+ D KDL EEYL+A
Sbjct: 841 PQVKNKMTKEQYIKMNRGINDSKDL-PEEYLSA 872
>AB209324-1|BAD92561.1| 1278|Homo sapiens brefeldin A-inhibited
guanine nucleotide-exchange protein 1 variant protein.
Length = 1278
Score = 30.3 bits (65), Expect = 6.7
Identities = 14/33 (42%), Positives = 21/33 (63%)
Frame = +2
Query: 350 PDVSDNEISSKFVKLFRGLKDVKDLINEEYLAA 448
P V + +++K+ RG+ D KDL EEYL+A
Sbjct: 319 PQVKNKMTKEQYIKMNRGINDSKDL-PEEYLSA 350
>BC050449-1|AAH50449.1| 832|Homo sapiens ARFGEF2 protein protein.
Length = 832
Score = 29.9 bits (64), Expect = 8.9
Identities = 14/36 (38%), Positives = 22/36 (61%)
Frame = +2
Query: 350 PDVSDNEISSKFVKLFRGLKDVKDLINEEYLAASIE 457
P V + +++K+ RG+ D KDL EEYL++ E
Sbjct: 786 PQVKNKMTKEQYIKMNRGINDSKDL-PEEYLSSIYE 820
>AL121903-1|CAI19614.1| 1785|Homo sapiens ADP-ribosylation factor
guanine nucleotide-exchange factor 2 (brefeldin A-inhib
protein.
Length = 1785
Score = 29.9 bits (64), Expect = 8.9
Identities = 14/36 (38%), Positives = 22/36 (61%)
Frame = +2
Query: 350 PDVSDNEISSKFVKLFRGLKDVKDLINEEYLAASIE 457
P V + +++K+ RG+ D KDL EEYL++ E
Sbjct: 786 PQVKNKMTKEQYIKMNRGINDSKDL-PEEYLSSIYE 820
>AL049537-1|CAI19320.1| 1785|Homo sapiens ADP-ribosylation factor
guanine nucleotide-exchange factor 2 (brefeldin A-inhib
protein.
Length = 1785
Score = 29.9 bits (64), Expect = 8.9
Identities = 14/36 (38%), Positives = 22/36 (61%)
Frame = +2
Query: 350 PDVSDNEISSKFVKLFRGLKDVKDLINEEYLAASIE 457
P V + +++K+ RG+ D KDL EEYL++ E
Sbjct: 786 PQVKNKMTKEQYIKMNRGINDSKDL-PEEYLSSIYE 820
>AK126902-1|BAC86743.1| 247|Homo sapiens protein ( Homo sapiens
cDNA FLJ44954 fis, clone BRAWH2010364. ).
Length = 247
Score = 29.9 bits (64), Expect = 8.9
Identities = 13/38 (34%), Positives = 17/38 (44%), Gaps = 1/38 (2%)
Frame = -3
Query: 617 YCPISCCYTCRRFCTLS-RPMCSI*ERDVCNFRNGPCC 507
+C C C C+L P CS+ C+ R PCC
Sbjct: 77 HCSPCCSLRCSPCCSLHCSPCCSLRCSPCCSLRCSPCC 114
>AK090647-1|BAC03496.1| 353|Homo sapiens protein.
Length = 353
Score = 29.9 bits (64), Expect = 8.9
Identities = 13/38 (34%), Positives = 17/38 (44%), Gaps = 1/38 (2%)
Frame = -3
Query: 617 YCPISCCYTCRRFCTLS-RPMCSI*ERDVCNFRNGPCC 507
+C C C C+L P CS+ C+ R PCC
Sbjct: 77 HCSPCCSLRCSPCCSLHCSPCCSLRCSPCCSLRCSPCC 114
>AF084521-1|AAD38428.1| 1785|Homo sapiens brefeldin A-inhibited
guanine nucleotide-exchange protein 2 protein.
Length = 1785
Score = 29.9 bits (64), Expect = 8.9
Identities = 14/36 (38%), Positives = 22/36 (61%)
Frame = +2
Query: 350 PDVSDNEISSKFVKLFRGLKDVKDLINEEYLAASIE 457
P V + +++K+ RG+ D KDL EEYL++ E
Sbjct: 786 PQVKNKMTKEQYIKMNRGINDSKDL-PEEYLSSIYE 820
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 98,132,691
Number of Sequences: 237096
Number of extensions: 2078509
Number of successful extensions: 5742
Number of sequences better than 10.0: 41
Number of HSP's better than 10.0 without gapping: 5370
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5719
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 7839245960
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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