Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P01_F_L24
(670 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q56CY6 Cluster: Acetoacetyl-CoA thiolase; n=5; cellular... 337 1e-91
UniRef50_P24752 Cluster: Acetyl-CoA acetyltransferase, mitochond... 291 8e-78
UniRef50_Q6L8K7 Cluster: Acetyl-CoA acetyltransferase; n=40; cel... 212 6e-54
UniRef50_Q6P3T4 Cluster: ACAT1 protein; n=3; Coelomata|Rep: ACAT... 202 6e-51
UniRef50_UPI0001509D0E Cluster: acetyl-CoA acyltransferases fami... 187 2e-46
UniRef50_Q8RC88 Cluster: Acetyl-CoA acetyltransferases; n=2; Bac... 180 2e-44
UniRef50_Q87GW1 Cluster: Acetyl-CoA acetyltransferase; n=41; Bac... 179 5e-44
UniRef50_P41338 Cluster: Acetyl-CoA acetyltransferase; n=104; ro... 178 9e-44
UniRef50_P14611 Cluster: Acetyl-CoA acetyltransferase; n=43; Bac... 178 9e-44
UniRef50_A4G2P1 Cluster: Acetyl-CoA acetyltransferase; n=10; Bac... 175 1e-42
UniRef50_Q9K6C8 Cluster: Acetyl-CoA acetyltransferase; n=6; Firm... 173 3e-42
UniRef50_O29070 Cluster: 3-ketoacyl-CoA thiolase; n=2; cellular ... 164 2e-39
UniRef50_P54810 Cluster: Acetyl-CoA acetyltransferase; n=122; Ba... 161 1e-38
UniRef50_Q67RA4 Cluster: Acetyl-CoA acetyltransferase; n=5; Bact... 158 1e-37
UniRef50_Q2GA69 Cluster: Acetyl-CoA C-acetyltransferase; n=2; Al... 153 5e-36
UniRef50_Q1GV21 Cluster: Acetyl-CoA C-acetyltransferase; n=66; B... 151 2e-35
UniRef50_Q62JZ3 Cluster: Beta-ketothiolase; n=107; Bacteria|Rep:... 149 8e-35
UniRef50_Q0UU17 Cluster: Putative uncharacterized protein; n=1; ... 148 1e-34
UniRef50_Q8CAY6 Cluster: Acetyl-CoA acetyltransferase, cytosolic... 147 2e-34
UniRef50_Q9BWD1 Cluster: Acetyl-CoA acetyltransferase, cytosolic... 146 3e-34
UniRef50_A1I8P5 Cluster: Acetyl-CoA C-acetyltransferase; n=6; Ba... 146 4e-34
UniRef50_A4SMV2 Cluster: Acetyl-CoA acetyltransferase; n=1; Aero... 144 2e-33
UniRef50_P45855 Cluster: Acetyl-CoA acetyltransferase; n=32; Bac... 144 2e-33
UniRef50_A1WCB0 Cluster: Acetyl-CoA acetyltransferases; n=36; Pr... 142 5e-33
UniRef50_O51136 Cluster: Acetyl-CoA C-acetyltransferase; n=3; Bo... 140 3e-32
UniRef50_A2DM80 Cluster: Acetyl-CoA acyltransferases family prot... 139 5e-32
UniRef50_Q236D4 Cluster: Acetyl-CoA acyltransferases family prot... 139 6e-32
UniRef50_Q577L1 Cluster: PhbA-2, acetyl-CoA acetyltransferase; n... 137 2e-31
UniRef50_A1SHM4 Cluster: Acetyl-CoA acetyltransferases; n=8; Bac... 137 2e-31
UniRef50_P42765 Cluster: 3-ketoacyl-CoA thiolase, mitochondrial;... 136 3e-31
UniRef50_A1SPA4 Cluster: Acetyl-CoA acetyltransferases; n=6; Bac... 136 5e-31
UniRef50_Q8ESF0 Cluster: Thiolase B; n=5; Bacteria|Rep: Thiolase... 136 6e-31
UniRef50_A0NJ40 Cluster: Acetyl-CoA C-acetyltransferase-like pro... 136 6e-31
UniRef50_Q4TEZ1 Cluster: Chromosome undetermined SCAF4980, whole... 135 1e-30
UniRef50_Q6KYW2 Cluster: Acetyl-CoA acetyltransferase; n=4; Ther... 134 2e-30
UniRef50_Q43974 Cluster: Beta-ketoadipyl-CoA thiolase; n=274; Ba... 133 3e-30
UniRef50_Q8D6N4 Cluster: Acetyl-CoA acetyltransferase; n=14; Vib... 133 4e-30
UniRef50_Q5UX35 Cluster: Acetyl-coA acetyltransferase; n=1; Halo... 132 7e-30
UniRef50_Q1VJ45 Cluster: Acetyl-CoA acetyltransferase; n=1; Psyc... 132 1e-29
UniRef50_Q835L3 Cluster: Acetyl-CoA acetyltransferase/hydroxymet... 128 2e-28
UniRef50_Q0AYU4 Cluster: Acetyl-CoA C-acetyltransferase; n=4; Cl... 128 2e-28
UniRef50_A5UXI0 Cluster: Acetyl-CoA acetyltransferase; n=5; cell... 127 2e-28
UniRef50_A6CQ12 Cluster: Acetyl-CoA acetyltransferase; n=1; Baci... 126 4e-28
UniRef50_Q74IF9 Cluster: Acetyl-CoA acetyltransferase; n=5; Lact... 124 2e-27
UniRef50_Q9RRK9 Cluster: Acetyl-CoA acetyltransferase; n=12; Bac... 124 3e-27
UniRef50_Q8ESG3 Cluster: Acetyl-CoA acetyltransferase; n=4; Firm... 122 8e-27
UniRef50_Q0SDR4 Cluster: Acetyl-CoA C-acetyltransferase; n=31; B... 121 1e-26
UniRef50_Q21BM7 Cluster: Acetyl-CoA C-acetyltransferase; n=1; Rh... 116 4e-25
UniRef50_A6T953 Cluster: Putative acetyl-CoA acetyltransferase; ... 116 7e-25
UniRef50_Q9YA31 Cluster: Acetyl-CoA acetyltransferase; n=1; Aero... 115 1e-24
UniRef50_P73825 Cluster: Acetyl coenzyme A acetyltransferase; n=... 113 3e-24
UniRef50_Q0K0C1 Cluster: Acetyl-CoA acetyltransferase; n=11; Pro... 113 3e-24
UniRef50_Q9RZA1 Cluster: Acetyl-CoA acetyltransferase; n=4; root... 110 3e-23
UniRef50_Q82UG2 Cluster: Thiolase; n=98; Bacteria|Rep: Thiolase ... 109 6e-23
UniRef50_Q97W61 Cluster: Acetyl-CoA c-acetyltransferase; n=22; c... 106 6e-22
UniRef50_UPI000038DFAF Cluster: hypothetical protein Faci_030015... 104 2e-21
UniRef50_Q7NUH9 Cluster: Acetyl-CoA C-acyltransferase; n=51; Bac... 103 3e-21
UniRef50_A3LMS9 Cluster: Acetyl-CoA C-acyltransferase, peroxisom... 103 3e-21
UniRef50_Q4DNU4 Cluster: Putative uncharacterized protein; n=1; ... 101 1e-20
UniRef50_Q8EN18 Cluster: Beta-ketothiolase; n=4; Bacteria|Rep: B... 101 2e-20
UniRef50_A0LKL0 Cluster: Acetyl-CoA acetyltransferases; n=1; Syn... 101 2e-20
UniRef50_A1SXV9 Cluster: Acetyl-CoA acetyltransferases; n=1; Psy... 100 3e-20
UniRef50_A1SFE7 Cluster: Acetyl-CoA acetyltransferases; n=11; Ba... 100 3e-20
UniRef50_Q89DN9 Cluster: Acetyl-CoA acetyltransferase; n=1; Brad... 100 6e-20
UniRef50_Q8NN21 Cluster: Acetyl-CoA acetyltransferases; n=9; Cor... 99 8e-20
UniRef50_Q0LZF8 Cluster: Acetyl-CoA C-acetyltransferase; n=3; Ba... 98 1e-19
UniRef50_Q9RUF8 Cluster: Acetyl-CoA acetyltransferase; n=144; ce... 97 3e-19
UniRef50_A3Q406 Cluster: Acetyl-CoA acetyltransferases; n=22; Ac... 96 6e-19
UniRef50_Q8IKW7 Cluster: Acetyl-CoA acetyltransferase, putative;... 96 6e-19
UniRef50_Q2QAP2 Cluster: Acetyl-CoA acetyltransferase; n=2; envi... 96 8e-19
UniRef50_Q0LKV2 Cluster: Acetyl-CoA C-acyltransferase; n=2; cell... 94 3e-18
UniRef50_Q2IN02 Cluster: Acetyl-CoA C-acyltransferase; n=3; Myxo... 93 4e-18
UniRef50_A0JU34 Cluster: Acetyl-CoA acetyltransferases; n=37; Ac... 93 4e-18
UniRef50_Q39N04 Cluster: Acetyl-CoA C-acetyltransferase; n=29; B... 93 6e-18
UniRef50_Q8SXL6 Cluster: RE07481p; n=1; Drosophila melanogaster|... 93 6e-18
UniRef50_A5UWB8 Cluster: Acetyl-CoA acetyltransferase; n=3; Bact... 93 7e-18
UniRef50_Q0EXX9 Cluster: Acetyl-CoA acyltransferase; n=2; Proteo... 61 1e-17
UniRef50_A0JVH9 Cluster: Acetyl-CoA acetyltransferases; n=20; Ba... 91 2e-17
UniRef50_Q22106 Cluster: Putative uncharacterized protein; n=1; ... 91 3e-17
UniRef50_Q2J8N8 Cluster: Acetyl-CoA C-acyltransferase; n=64; Bac... 90 5e-17
UniRef50_Q08VP3 Cluster: 3-ketoacyl-CoA thiolase; n=1; Stigmatel... 89 1e-16
UniRef50_A1IDF1 Cluster: Acetyl-CoA C-acyltransferase; n=1; Cand... 88 2e-16
UniRef50_Q2UTB1 Cluster: RIB40 genomic DNA, SC005; n=6; Ascomyco... 88 2e-16
UniRef50_Q8KXD4 Cluster: Beta-ketothiolase; n=11; Proteobacteria... 88 2e-16
UniRef50_Q18QM7 Cluster: Acetyl-CoA acetyltransferases; n=2; Des... 88 2e-16
UniRef50_P27796 Cluster: 3-ketoacyl-CoA thiolase, peroxisomal pr... 87 3e-16
UniRef50_Q39TD0 Cluster: Thiolase; n=1; Geobacter metallireducen... 87 4e-16
UniRef50_A6DTH4 Cluster: Acetyl-CoA acetyltransferase; n=1; Lent... 87 4e-16
UniRef50_Q5C0R7 Cluster: SJCHGC03323 protein; n=1; Schistosoma j... 86 6e-16
UniRef50_Q9HZJ3 Cluster: 3-ketoacyl-CoA thiolase; n=153; Bacteri... 86 8e-16
UniRef50_Q5YQT4 Cluster: Putative acyl-CoA thiolase; n=1; Nocard... 85 1e-15
UniRef50_A4TXT3 Cluster: Acetyl-CoA acetyltransferase; n=1; Magn... 85 1e-15
UniRef50_Q0RXS1 Cluster: Acetyl-CoA C-acetyltransferase; n=1; Rh... 85 1e-15
UniRef50_Q47DJ3 Cluster: Thiolase; n=2; Bacteria|Rep: Thiolase -... 85 2e-15
UniRef50_A4BBG3 Cluster: Acetyl-CoA acetyltransferase; n=1; Rein... 85 2e-15
UniRef50_A0E400 Cluster: Chromosome undetermined scaffold_77, wh... 85 2e-15
UniRef50_A7AWF2 Cluster: Thiolase, N-terminal and C-terminal dom... 84 3e-15
UniRef50_Q9AA29 Cluster: Thiolase family protein; n=42; Bacteria... 83 8e-15
UniRef50_Q2RNW4 Cluster: Acetyl-CoA C-acetyltransferase precurso... 82 1e-14
UniRef50_Q11I56 Cluster: Acetyl-CoA acetyltransferases; n=26; Pr... 80 4e-14
UniRef50_Q9KWK4 Cluster: Putative acetyl-CoA C-acetyltransferase... 80 5e-14
UniRef50_P21775-2 Cluster: Isoform 2 of P21775 ; n=4; Euarchonto... 79 7e-14
UniRef50_Q8SVA6 Cluster: Similarity to 3-KETOACYL COA THIOLASE; ... 79 1e-13
UniRef50_Q5P0L6 Cluster: Putative beta-ketothiolase; n=2; Azoarc... 78 2e-13
UniRef50_Q2PQZ1 Cluster: Beta-ketothiolase; n=1; Rhodococcus sp.... 78 2e-13
UniRef50_A1I8F4 Cluster: Acetyl-CoA C-acyltransferase; n=1; Cand... 77 4e-13
UniRef50_A1D2F8 Cluster: 3-ketoacyl-CoA ketothiolase (Kat1), put... 77 4e-13
UniRef50_A0JWS0 Cluster: Acetyl-CoA acetyltransferases; n=2; Art... 76 9e-13
UniRef50_Q4Q698 Cluster: Thiolase protein-like protein; n=7; Try... 76 9e-13
UniRef50_Q81Y70 Cluster: Acetyl-CoA acetyltransferase; n=11; Bac... 75 1e-12
UniRef50_Q128L5 Cluster: Acetyl-CoA C-acyltransferase; n=13; Pro... 75 1e-12
UniRef50_Q5UWD8 Cluster: Acetyl-coA acetyltransferase; n=6; Halo... 75 1e-12
UniRef50_Q8NCW8 Cluster: 3-oxoacyl-CoA thiolase; n=21; Fungi/Met... 75 2e-12
UniRef50_P09110 Cluster: 3-ketoacyl-CoA thiolase, peroxisomal pr... 75 2e-12
UniRef50_A5DXV8 Cluster: 3-ketoacyl-CoA thiolase B; n=5; Dikarya... 74 4e-12
UniRef50_Q05493 Cluster: 3-ketoacyl-CoA thiolase, peroxisomal pr... 73 5e-12
UniRef50_P55084 Cluster: Trifunctional enzyme subunit beta, mito... 70 4e-11
UniRef50_Q5WL68 Cluster: Acetyl-CoA acetyltransferase; n=1; Baci... 69 8e-11
UniRef50_Q9AG66 Cluster: Beta ketothiolase; n=5; Rhizobiaceae|Re... 69 8e-11
UniRef50_Q02X83 Cluster: Acetyl-CoA acetyltransferase; n=2; Lact... 69 8e-11
UniRef50_O28040 Cluster: 3-ketoacyl-CoA thiolase; n=12; Archaea|... 69 1e-10
UniRef50_A4F8Z3 Cluster: Acetyl-CoA acetyltransferase; n=2; Acti... 68 2e-10
UniRef50_Q6MM13 Cluster: Acetyl-CoA acyltransferase; n=2; Proteo... 66 7e-10
UniRef50_Q565U8 Cluster: 3-oxoacyl-CoA thiolase; n=1; uncultured... 66 1e-09
UniRef50_Q3INC2 Cluster: Acetyl-CoA C-acyltransferase 5; n=1; Na... 66 1e-09
UniRef50_A6GTF1 Cluster: Acetyl-CoA C-acyltransferase; n=1; Limn... 64 2e-09
UniRef50_Q89H19 Cluster: Acyl-CoA thiolase; n=4; Proteobacteria|... 64 4e-09
UniRef50_Q63YX8 Cluster: Beta-ketoadipyl CoA thiolase; n=96; cel... 63 7e-09
UniRef50_Q9KT59 Cluster: 3-ketoacyl-CoA thiolase; n=113; Proteob... 62 2e-08
UniRef50_A1SKA8 Cluster: Acetyl-CoA acetyltransferases; n=24; Ac... 61 3e-08
UniRef50_Q1GSM2 Cluster: Acetyl-CoA C-acyltransferase; n=20; Pro... 60 6e-08
UniRef50_A6G214 Cluster: Putative uncharacterized protein; n=1; ... 60 6e-08
UniRef50_A1FU75 Cluster: Acetyl-CoA acetyltransferases; n=5; Xan... 59 1e-07
UniRef50_Q9F8Q0 Cluster: 3-ketoacyl-CoA thiolase; n=1; Carboxydo... 58 2e-07
UniRef50_Q1GWY7 Cluster: Acetyl-CoA C-acyltransferase; n=4; Bact... 58 2e-07
UniRef50_Q96CA6 Cluster: ACAA1 protein; n=16; Tetrapoda|Rep: ACA... 44 2e-07
UniRef50_Q6ACV5 Cluster: Acetyl-coA acyltransferase; n=2; Actino... 58 3e-07
UniRef50_Q7QZB1 Cluster: GLP_567_7442_8677; n=1; Giardia lamblia... 57 3e-07
UniRef50_Q0FF19 Cluster: Putative acetyl-CoA c-acetyltransferase... 57 4e-07
UniRef50_A6GHQ8 Cluster: Acetyl-CoA acetyltransferase; n=1; Ples... 56 6e-07
UniRef50_Q1AV81 Cluster: Thiolase; n=3; Actinobacteria (class)|R... 56 8e-07
UniRef50_A0NXK3 Cluster: Acetyl-CoA C-acetyltransferase; n=2; Al... 56 8e-07
UniRef50_A0Z3Q6 Cluster: Acetyl-CoA acetyltransferase; n=1; mari... 54 3e-06
UniRef50_Q8F7W4 Cluster: Acetyl-CoA acetyltransferase; n=4; Lept... 53 7e-06
UniRef50_Q184F9 Cluster: Putative thiolase; n=2; Clostridium dif... 53 7e-06
UniRef50_Q13HG7 Cluster: Acetyl-CoA C-acetyltransferase; n=1; Bu... 52 1e-05
UniRef50_A5WF94 Cluster: Acetyl-CoA acetyltransferase; n=72; Bac... 52 2e-05
UniRef50_A5V6H6 Cluster: Thiolase; n=5; Proteobacteria|Rep: Thio... 50 5e-05
UniRef50_A1W8A4 Cluster: Acetyl-CoA acetyltransferases; n=3; Com... 49 9e-05
UniRef50_UPI000065EB0A Cluster: 3-ketoacyl-CoA thiolase, peroxis... 49 1e-04
UniRef50_UPI00006A0465 Cluster: 3-ketoacyl-CoA thiolase, peroxis... 48 2e-04
UniRef50_A3N0P7 Cluster: 3-ketoacyl-CoA thiolase; n=1; Actinobac... 48 2e-04
UniRef50_Q1GCU4 Cluster: Acetyl-CoA C-acetyltransferase; n=2; Rh... 47 4e-04
UniRef50_Q1GUF0 Cluster: Acetyl-CoA C-acyltransferase; n=2; Prot... 46 6e-04
UniRef50_A6RBW5 Cluster: Putative uncharacterized protein; n=1; ... 46 6e-04
UniRef50_Q4TEZ0 Cluster: Chromosome undetermined SCAF4980, whole... 46 8e-04
UniRef50_Q1M689 Cluster: Putative thiolase; n=1; Rhizobium legum... 46 0.001
UniRef50_A7IGV8 Cluster: Acetyl-CoA acetyltransferase; n=1; Xant... 45 0.001
UniRef50_UPI000023DFFE Cluster: hypothetical protein FG09503.1; ... 43 0.006
UniRef50_UPI00006D84CA Cluster: COG0183: Acetyl-CoA acetyltransf... 42 0.018
UniRef50_A3K5J3 Cluster: Acetyl-CoA acetyltransferase; n=1; Sagi... 41 0.024
UniRef50_Q7NDK9 Cluster: Gll4226 protein; n=1; Gloeobacter viola... 40 0.041
UniRef50_A6EZZ3 Cluster: Beta-ketoadipyl CoA thiolase PcaF; n=1;... 40 0.041
UniRef50_Q96X18 Cluster: Acetyl-CoA acetyltransferase; n=1; Lacc... 40 0.054
UniRef50_Q3D2X0 Cluster: Thiolase; n=7; Streptococcus agalactiae... 39 0.095
UniRef50_Q84FL0 Cluster: AdmM; n=4; Gammaproteobacteria|Rep: Adm... 39 0.13
UniRef50_Q5VKR9 Cluster: Ketoacyl-ACP synthase; n=2; Saccharopol... 39 0.13
UniRef50_A4KCE5 Cluster: Tautomycetin biosynthetic PKS; n=1; Str... 38 0.22
UniRef50_Q93NX9 Cluster: AmphI; n=5; Bacteria|Rep: AmphI - Strep... 38 0.29
UniRef50_Q0QMN6 Cluster: Polyketide synthase type I; n=1; Strept... 38 0.29
UniRef50_A5KPS6 Cluster: Putative uncharacterized protein; n=1; ... 38 0.29
UniRef50_Q5XDB2 Cluster: Acetyl-CoA acetyltransferase; n=11; Str... 37 0.38
UniRef50_Q3A171 Cluster: 3-oxoacyl-(Acyl-carrier-protein) syntha... 37 0.38
UniRef50_A1GD41 Cluster: Acyl transferase region; n=1; Salinispo... 37 0.51
UniRef50_Q93NW6 Cluster: AmphC; n=1; Streptomyces nodosus|Rep: A... 36 0.67
UniRef50_Q9S0R3 Cluster: Type I polyketide synthase AVES 4; n=2;... 36 0.88
UniRef50_Q9L4X3 Cluster: NysI; n=4; root|Rep: NysI - Streptomyce... 36 0.88
UniRef50_Q8RL72 Cluster: MmpIV; n=3; cellular organisms|Rep: Mmp... 36 0.88
UniRef50_Q84HM3 Cluster: PksE; n=1; Lechevalieria aerocolonigene... 36 0.88
UniRef50_Q6V1M7 Cluster: Plm2-3; n=1; Streptomyces sp. HK803|Rep... 36 0.88
UniRef50_A4KCE4 Cluster: Tautomycetin biosynthetic PKS; n=2; cel... 36 0.88
UniRef50_A4FCY9 Cluster: Modular polyketide synthase; n=3; cellu... 36 0.88
UniRef50_A1YAM7 Cluster: Polyketide synthase type I; n=3; Actino... 36 0.88
UniRef50_A1GGE4 Cluster: Beta-ketoacyl synthase; n=1; Salinispor... 36 0.88
UniRef50_Q92GI8 Cluster: Similarity to acetyl-CoA acetyltransfer... 36 1.2
UniRef50_Q6W5P6 Cluster: FscD; n=6; Bacteria|Rep: FscD - Strepto... 36 1.2
UniRef50_Q3S864 Cluster: Nodular polyketide synthase; n=15; Bact... 36 1.2
UniRef50_Q0QMQ1 Cluster: Polyketide synthase type I; n=1; Strept... 36 1.2
UniRef50_Q0P7K1 Cluster: Putative hybrid non-ribosomal peptide-p... 36 1.2
UniRef50_Q09DD1 Cluster: Type I polyketide synthase PikAI; n=1; ... 36 1.2
UniRef50_Q099Y5 Cluster: Oxidoreductase, short chain dehydrogena... 36 1.2
UniRef50_Q4P0A3 Cluster: Putative uncharacterized protein; n=2; ... 36 1.2
UniRef50_Q93HI8 Cluster: Modular polyketide synthase; n=1; Strep... 35 1.5
UniRef50_Q9EWA1 Cluster: PimS2 protein; n=2; Streptomyces|Rep: P... 35 1.5
UniRef50_Q846X2 Cluster: Monensin polyketide synthase modules 7 ... 35 1.5
UniRef50_Q3W1C5 Cluster: Beta-ketoacyl synthase:Acyl transferase... 35 1.5
UniRef50_Q3S863 Cluster: Modular polyketide synthase; n=1; Strep... 35 1.5
UniRef50_Q0RLH1 Cluster: Putative polyketide synthase; n=1; Fran... 35 1.5
UniRef50_Q0QMP8 Cluster: Polyketide synthase type I; n=1; Strept... 35 1.5
UniRef50_Q0QMN5 Cluster: Polyketide synthase type I; n=1; Strept... 35 1.5
UniRef50_A6GK65 Cluster: Polyketide synthase type I; n=2; Plesio... 35 1.5
UniRef50_A4X8L0 Cluster: Beta-ketoacyl synthase; n=1; Salinispor... 35 1.5
UniRef50_A1YAM9 Cluster: Polyketide synthase type I; n=5; cellul... 35 1.5
UniRef50_Q58944 Cluster: Uncharacterized protein MJ1549; n=18; E... 35 1.5
UniRef50_Q03132 Cluster: Erythronolide synthase, modules 3 and 4... 35 1.5
UniRef50_Q3ZXT9 Cluster: 3-oxoacyl-[acyl-carrier-protein] syntha... 35 2.0
UniRef50_Q9L4W3 Cluster: NysC; n=3; Actinomycetales|Rep: NysC - ... 35 2.0
UniRef50_Q76KY0 Cluster: Polyketide synthase modules 1-3; n=2; c... 35 2.0
UniRef50_Q6JHN6 Cluster: ObsC; n=1; Saccharopolyspora spinosa|Re... 35 2.0
UniRef50_Q3S868 Cluster: Modular polyketide synthase; n=1; Strep... 35 2.0
UniRef50_Q1MX73 Cluster: Type I polyketide synthase; n=1; Strept... 35 2.0
UniRef50_Q1MX72 Cluster: Type I polyketide synthase; n=2; Strept... 35 2.0
UniRef50_P95814 Cluster: FK506 polyketide synthase; n=2; Strepto... 35 2.0
UniRef50_A5IHN4 Cluster: 3-oxoacyl-(Acyl carrier protein) syntha... 35 2.0
UniRef50_Q9L8C7 Cluster: Polyketide synthase; n=8; Sorangium cel... 34 2.7
UniRef50_Q76KZ5 Cluster: Polyketide synthase modules 4; n=1; Str... 34 2.7
UniRef50_Q6W5P8 Cluster: FscF; n=3; Streptomyces|Rep: FscF - Str... 34 2.7
UniRef50_Q52V50 Cluster: Polyketide synthase type I; n=7; cellul... 34 2.7
UniRef50_Q4U446 Cluster: DszB; n=2; cellular organisms|Rep: DszB... 34 2.7
UniRef50_Q3W1F1 Cluster: Beta-ketoacyl synthase:Acyl transferase... 34 2.7
UniRef50_Q1RS52 Cluster: Polyketide synthase type I; n=3; Bacter... 34 2.7
UniRef50_Q1RS45 Cluster: Polyketide synthase type I; n=4; cellul... 34 2.7
UniRef50_Q0VZ72 Cluster: Polyketide synthase; n=1; Chondromyces ... 34 2.7
UniRef50_Q0RTS5 Cluster: Putative Type I modular polyketide synt... 34 2.7
UniRef50_Q0LKI5 Cluster: Beta-ketoacyl synthase; n=1; Herpetosip... 34 2.7
UniRef50_A4F5D6 Cluster: Polyketide synthase; n=5; cellular orga... 34 2.7
UniRef50_A0ACH1 Cluster: Putative polyketide synthase B; n=5; Ba... 34 2.7
UniRef50_Q9EX53 Cluster: Putative type I polyketide synthase; n=... 34 3.6
UniRef50_Q82QT4 Cluster: Modular polyketide synthase; n=3; Strep... 34 3.6
UniRef50_Q9KIV4 Cluster: 8,8a-deoxyoleandolide synthase 1; n=1; ... 34 3.6
UniRef50_Q8RJY6 Cluster: StiA protein; n=1; Stigmatella aurantia... 34 3.6
UniRef50_Q83WF0 Cluster: Protomycinolide IV synthase 1; n=18; ce... 34 3.6
UniRef50_Q83WE8 Cluster: Protomycinolide IV synthase 3; n=2; Mic... 34 3.6
UniRef50_Q6W5P9 Cluster: FscB; n=6; Streptomyces|Rep: FscB - Str... 34 3.6
UniRef50_Q3S869 Cluster: Modular polyketide synthase; n=2; Strep... 34 3.6
UniRef50_Q0QMN7 Cluster: Polyketide synthase type I; n=1; Strept... 34 3.6
UniRef50_A7GF25 Cluster: DNA (Cytosine-5-)-methyltransferase; n=... 34 3.6
UniRef50_A1YAN0 Cluster: Polyketide synthase type I; n=3; cellul... 34 3.6
UniRef50_A1AMI5 Cluster: Beta-ketoacyl synthase; n=1; Pelobacter... 34 3.6
UniRef50_A0FCL2 Cluster: MerB; n=4; cellular organisms|Rep: MerB... 34 3.6
UniRef50_Q859P9 Cluster: Virion RNA polymerase; n=1; Enterobacte... 34 3.6
UniRef50_Q07017 Cluster: Oleandomycin polyketide synthase, modul... 34 3.6
UniRef50_Q93H85 Cluster: Modular polyketide synthase; n=4; Bacte... 33 4.7
UniRef50_Q63LK8 Cluster: Putative polyketide synthase; n=30; cel... 33 4.7
UniRef50_Q5VKR4 Cluster: Type I PKS; n=7; Actinomycetales|Rep: T... 33 4.7
UniRef50_Q4U447 Cluster: DszA; n=4; cellular organisms|Rep: DszA... 33 4.7
UniRef50_Q2N3S8 Cluster: Polyketide synthase; n=2; Bacteria|Rep:... 33 4.7
UniRef50_Q0PD02 Cluster: Type I polyketide synthase; n=2; Strept... 33 4.7
UniRef50_Q0B307 Cluster: Beta-ketoacyl synthase; n=1; Burkholder... 33 4.7
UniRef50_Q09DD3 Cluster: MxaC; n=1; Stigmatella aurantiaca DW4/3... 33 4.7
UniRef50_O54666 Cluster: RifA; n=4; Actinomycetales|Rep: RifA - ... 33 4.7
UniRef50_O30479 Cluster: PKS module 1; n=2; Streptomyces hygrosc... 33 4.7
UniRef50_A4X3P8 Cluster: Beta-ketoacyl synthase; n=1; Salinispor... 33 4.7
UniRef50_A3R4R6 Cluster: Polyketide synthase; n=1; Streptomyces ... 33 4.7
UniRef50_A0W5R6 Cluster: Beta-ketoacyl synthase; n=1; Geobacter ... 33 4.7
UniRef50_Q1E349 Cluster: Putative uncharacterized protein; n=1; ... 33 4.7
UniRef50_A2QWP6 Cluster: Catalytic activity: 6 Malonyl-CoA + Pro... 33 4.7
UniRef50_Q9S0R7 Cluster: Type I polyketide synthase AVES 2; n=1;... 33 6.2
UniRef50_Q93H84 Cluster: Modular polyketide synthase; n=2; Strep... 33 6.2
UniRef50_Q2J8Q4 Cluster: Beta-ketoacyl synthase; n=1; Frankia sp... 33 6.2
UniRef50_Q9L4X2 Cluster: NysJ; n=3; Streptomyces|Rep: NysJ - Str... 33 6.2
UniRef50_Q9L4X1 Cluster: NysK; n=1; Streptomyces noursei|Rep: Ny... 33 6.2
UniRef50_Q9ALM2 Cluster: Polyketide synthase extender modules 8-... 33 6.2
UniRef50_Q8KUH4 Cluster: Polyketide synthase; n=1; Actinosynnema... 33 6.2
UniRef50_Q846X3 Cluster: Monensin polyketide synthase modules 5 ... 33 6.2
UniRef50_Q6VT93 Cluster: Mixed type I polyketide synthase-peptid... 33 6.2
UniRef50_Q6TLJ9 Cluster: Polyketide synthase type I; n=1; Pseudo... 33 6.2
UniRef50_Q6GVP0 Cluster: Possible polyketide synthase; n=15; Act... 33 6.2
UniRef50_Q52V53 Cluster: Polyketide synthase type I; n=4; cellul... 33 6.2
UniRef50_Q3VXM8 Cluster: Beta-ketoacyl synthase:Acyl transferase... 33 6.2
UniRef50_Q1WEK8 Cluster: Polyketide synthase; n=1; Streptomyces ... 33 6.2
UniRef50_Q1Q275 Cluster: Similar to beta-ketoacyl (Acyl carrier ... 33 6.2
UniRef50_Q1K1L4 Cluster: Beta-hydroxyacyl-(Acyl-carrier-protein)... 33 6.2
UniRef50_Q0S8W4 Cluster: Type I polyketide synthase; n=2; Rhodoc... 33 6.2
UniRef50_A6PQN7 Cluster: Beta-ketoacyl synthase precursor; n=1; ... 33 6.2
UniRef50_A6G4P0 Cluster: Putative multi-domain beta keto-acyl sy... 33 6.2
UniRef50_A2W1N2 Cluster: Acetyl-CoA acetyltransferase; n=6; Prot... 33 6.2
UniRef50_A0VU10 Cluster: Beta-ketoacyl synthase; n=1; Dinoroseob... 33 6.2
UniRef50_Q6RKI7 Cluster: Polyketide synthase; n=3; Sclerotiniace... 33 6.2
UniRef50_Q6RKE2 Cluster: Polyketide synthase; n=2; Pleosporales|... 33 6.2
UniRef50_Q0V1S1 Cluster: Putative uncharacterized protein; n=2; ... 33 6.2
UniRef50_UPI0000DADC27 Cluster: hypothetical protein RcanM_01000... 33 8.2
UniRef50_Q9S0R4 Cluster: Type I polyketide synthase AVES 3; n=1;... 33 8.2
UniRef50_Q93HJ5 Cluster: Modular polyketide synthase; n=5; Actin... 33 8.2
UniRef50_Q93HJ2 Cluster: Modular polyketide synthase; n=6; Bacte... 33 8.2
UniRef50_Q8RJY4 Cluster: StiC protein; n=1; Stigmatella aurantia... 33 8.2
UniRef50_Q8GBX4 Cluster: Polyketide synthase; n=2; Sorangium cel... 33 8.2
UniRef50_Q2PC83 Cluster: Putative polyketide synthase; n=2; Acti... 33 8.2
UniRef50_Q27W72 Cluster: NigAIII; n=1; Streptomyces violaceusnig... 33 8.2
UniRef50_Q27W71 Cluster: NigAIV; n=2; Streptomyces violaceusnige... 33 8.2
UniRef50_Q27W58 Cluster: NigAVII; n=6; cellular organisms|Rep: N... 33 8.2
UniRef50_Q1L0S5 Cluster: NapD; n=4; Streptomyces hygroscopicus|R... 33 8.2
UniRef50_Q0PCZ9 Cluster: Type I polyketide synthase; n=2; Strept... 33 8.2
UniRef50_Q090E0 Cluster: Oxidoreductase, short chain dehydrogena... 33 8.2
UniRef50_Q02DB0 Cluster: Beta-ketoacyl synthase precursor; n=2; ... 33 8.2
UniRef50_A6E0C0 Cluster: Putative uncharacterized protein; n=1; ... 33 8.2
UniRef50_A5FKY0 Cluster: Beta-ketoacyl synthase; n=6; Bacteria|R... 33 8.2
UniRef50_A4LZ00 Cluster: KR; n=1; Geobacter bemidjiensis Bem|Rep... 33 8.2
UniRef50_A1GFR6 Cluster: AMP-dependent synthetase and ligase; n=... 33 8.2
UniRef50_A0UXD4 Cluster: Condensation domain; n=1; Clostridium c... 33 8.2
UniRef50_A0FCL1 Cluster: MerA; n=2; Streptomyces|Rep: MerA - Str... 33 8.2
UniRef50_Q2TSW6 Cluster: Pyruvate kinase; n=1; Achlya bisexualis... 33 8.2
UniRef50_Q6RKI0 Cluster: Polyketide synthase; n=4; Pezizomycotin... 33 8.2
>UniRef50_Q56CY6 Cluster: Acetoacetyl-CoA thiolase; n=5; cellular
organisms|Rep: Acetoacetyl-CoA thiolase - Dendroctonus
jeffreyi (Jeffrey pine beetle)
Length = 398
Score = 337 bits (829), Expect = 1e-91
Identities = 153/223 (68%), Positives = 180/223 (80%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A +FAGLP S C T+NKVCASGMKSIML AQ LQTG+Q +++AGGMESMSN P+Y+KRG
Sbjct: 78 ATLFAGLPTSTICTTINKVCASGMKSIMLGAQALQTGSQEVVVAGGMESMSNAPYYMKRG 137
Query: 182 ETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAY 361
+T YGG+QLVDG+V DGLTDVYNK HMGNCAENTAKKL ITRQ QDE+ ++SY RSA A+
Sbjct: 138 QTPYGGVQLVDGVVLDGLTDVYNKVHMGNCAENTAKKLGITRQQQDEFGISSYLRSAQAW 197
Query: 362 EAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNASTL 541
+ + F ELVPV VPQK+G + ++DEEYKRVN EKF KL+T+FQ+ENGTVTA NASTL
Sbjct: 198 QNRVFDFELVPVSVPQKKGQDTVVSKDEEYKRVNIEKFCKLATIFQRENGTVTAANASTL 257
Query: 542 NDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
NDG +RLN+KP+ARIVGFADG CDPIDFPI P
Sbjct: 258 NDGAAALILTTRAAAERLNLKPLARIVGFADGACDPIDFPIAP 300
>UniRef50_P24752 Cluster: Acetyl-CoA acetyltransferase,
mitochondrial precursor; n=52; cellular organisms|Rep:
Acetyl-CoA acetyltransferase, mitochondrial precursor -
Homo sapiens (Human)
Length = 427
Score = 291 bits (715), Expect = 8e-78
Identities = 141/223 (63%), Positives = 164/223 (73%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
AV+ AGLP S C T+NKVCASGMK+IM+A+Q L G Q +++AGGMESMSNVP+ + RG
Sbjct: 107 AVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMNRG 166
Query: 182 ETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAY 361
T YGG++L D IV DGLTDVYNK HMG+CAENTAKKL I R +QD YA+NSY RS AA+
Sbjct: 167 STPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAW 226
Query: 362 EAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNASTL 541
EA F +E++PV V K V+ EDEEYKRV+F K KL TVFQKENGTVTA NASTL
Sbjct: 227 EAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKENGTVTAANASTL 286
Query: 542 NDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
NDG KRLNV P+ARIV FAD +PIDFPI P
Sbjct: 287 NDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAP 329
>UniRef50_Q6L8K7 Cluster: Acetyl-CoA acetyltransferase; n=40;
cellular organisms|Rep: Acetyl-CoA acetyltransferase -
Yarrowia lipolytica (Candida lipolytica)
Length = 397
Score = 212 bits (518), Expect = 6e-54
Identities = 108/222 (48%), Positives = 140/222 (63%)
Frame = +2
Query: 5 VIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGE 184
VI G P+S T+NKVC+SG+K++ LAAQ ++ G + +I+AGGMESMSN P+Y RG
Sbjct: 77 VIKGGFPESVEATTINKVCSSGLKTVALAAQAIKAGDRNVIVAGGMESMSNTPYYSGRGL 136
Query: 185 TSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYE 364
+G +L D IV DGL D YN HMGNC ENT K+ ITR+ QDEYA+ SY+R+ + +
Sbjct: 137 V-FGNQKLEDSIVKDGLWDPYNNIHMGNCCENTNKRDGITREQQDEYAIESYRRANESIK 195
Query: 365 AKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNASTLN 544
AF DE+VPV + ++G V +EDEE K N EK L VF K+ G+VTAGNAS +N
Sbjct: 196 NGAFKDEIVPVEIKTRKGT-VTVSEDEEPKGANAEKLKGLKPVFDKQ-GSVTAGNASPIN 253
Query: 545 DGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
DG K L +A+IV +AD PIDF I P
Sbjct: 254 DGASAVVVASGTKAKELGTPVLAKIVSYADAATAPIDFTIAP 295
>UniRef50_Q6P3T4 Cluster: ACAT1 protein; n=3; Coelomata|Rep: ACAT1
protein - Homo sapiens (Human)
Length = 289
Score = 202 bits (493), Expect = 6e-51
Identities = 99/159 (62%), Positives = 114/159 (71%)
Frame = +2
Query: 155 NVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVN 334
+VP+ + RG T YGG++L D IV DGLTDVYNK HMG+CAENTAKKL I R +QD YA+N
Sbjct: 124 HVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAIN 183
Query: 335 SYKRSAAAYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGT 514
SY RS AA+EA F +E++PV V K V+ EDEEYKRV+F K KL TVFQKENGT
Sbjct: 184 SYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKENGT 243
Query: 515 VTAGNASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFA 631
VTA NASTLNDG KRLNV P+ARIVG A
Sbjct: 244 VTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVGKA 282
>UniRef50_UPI0001509D0E Cluster: acetyl-CoA acyltransferases family
protein; n=1; Tetrahymena thermophila SB210|Rep:
acetyl-CoA acyltransferases family protein - Tetrahymena
thermophila SB210
Length = 389
Score = 187 bits (455), Expect = 2e-46
Identities = 102/226 (45%), Positives = 133/226 (58%), Gaps = 3/226 (1%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYL--- 172
A + AGLP C +VNKVCASGMKS+M A+Q +Q G +I+ GG ESMSNVPFY+
Sbjct: 71 AALAAGLPIGVNCYSVNKVCASGMKSVMQASQTIQLGQADVIICGGFESMSNVPFYVTNH 130
Query: 173 KRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSA 352
++G+ +G LVDG FDGLT+ Y+ MG CAE TA L+I R+ DEY V SY+R
Sbjct: 131 RKGQL-FGNQTLVDGAAFDGLTNFYDNKAMGFCAEKTAADLKIDRKQNDEYCVESYERVL 189
Query: 353 AAYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNA 532
A + F +++VPV V K I DEE R N K +L F NG TA N+
Sbjct: 190 KALKTPEFKNDIVPVTVQNK-----IVDADEEPLRYNKAKIPQLKPAF-TPNGVNTAANS 243
Query: 533 STLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
S LNDG K L +KP+A+++ +AD E +P+DF I P
Sbjct: 244 SKLNDGACILILMSEQKVKELQIKPLAKVLSYADAEVEPVDFCIAP 289
>UniRef50_Q8RC88 Cluster: Acetyl-CoA acetyltransferases; n=2;
Bacteria|Rep: Acetyl-CoA acetyltransferases -
Thermoanaerobacter tengcongensis
Length = 394
Score = 180 bits (439), Expect = 2e-44
Identities = 94/228 (41%), Positives = 134/228 (58%), Gaps = 5/228 (2%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
+ + AG+P T+N VC SG++++ +AAQ + G I++AGGMESMS P+ L+
Sbjct: 69 SAVKAGIPVEVPATTINMVCGSGLRTVAMAAQAVMLGDADIVVAGGMESMSRAPYLLRDA 128
Query: 182 ETSYG----GMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRS 349
Y +LVD +V+DGL DV+N++HMG AEN A++ +I+RQ+QDE+A+ S +
Sbjct: 129 RWGYRMNMPSGELVDEMVYDGLWDVFNQYHMGITAENIAERYKISRQEQDEFALRSQNLA 188
Query: 350 AAAYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYK-RVNFEKFTKLSTVFQKENGTVTAG 526
AA +A F +E+VPVP+PQK+G P+ F DE + E KL F K +GTVTAG
Sbjct: 189 EAAIKAGKFEEEIVPVPIPQKKGDPIEFKVDEHPRFGTTMEDLAKLKPAF-KPDGTVTAG 247
Query: 527 NASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
NAS +NDG K L V P+A I +A DP + P
Sbjct: 248 NASGINDGAAAVVVMSRDKAKELGVTPLATIKSYAYAGVDPAVMGLGP 295
>UniRef50_Q87GW1 Cluster: Acetyl-CoA acetyltransferase; n=41;
Bacteria|Rep: Acetyl-CoA acetyltransferase - Vibrio
parahaemolyticus
Length = 402
Score = 179 bits (436), Expect = 5e-44
Identities = 98/221 (44%), Positives = 135/221 (61%), Gaps = 5/221 (2%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLK-- 175
A +FAG+P+S VN VC SGMK++M A +++G I++A G+E MS +PF
Sbjct: 69 AALFAGIPESVPAYGVNMVCGSGMKTVMDAVSHIRSGDAEIVVAAGVEVMSQIPFAAPSS 128
Query: 176 -RGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSA 352
R G ++L D +V DGLTDVYN++HMG AEN AK++ +TRQ QDEYA++S +++
Sbjct: 129 IRDGNKMGNLELKDLLVADGLTDVYNQYHMGVTAENVAKEIGLTRQQQDEYALSSQQKAV 188
Query: 353 AAYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVN--FEKFTKLSTVFQKENGTVTAG 526
AA EA F DE+VPV V Q+R V+F + +EY + N E +KL F +E GTVTAG
Sbjct: 189 AAIEAGKFKDEIVPVEVQQRR-ETVLF-DTDEYPKANATMEALSKLRPAFDRE-GTVTAG 245
Query: 527 NASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDP 649
NAS +NDG K + P+A IV +A DP
Sbjct: 246 NASGINDGASAIIVASESAVKAHGLTPLAEIVSYAQSGLDP 286
>UniRef50_P41338 Cluster: Acetyl-CoA acetyltransferase; n=104;
root|Rep: Acetyl-CoA acetyltransferase - Saccharomyces
cerevisiae (Baker's yeast)
Length = 398
Score = 178 bits (434), Expect = 9e-44
Identities = 95/222 (42%), Positives = 127/222 (57%), Gaps = 3/222 (1%)
Frame = +2
Query: 14 AGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLK--RGET 187
AGL TVNKVCAS MK+I+L AQ ++ G +++AGG ESM+N P+Y+ R
Sbjct: 76 AGLSNHIVASTVNKVCASAMKAIILGAQSIKCGNADVVVAGGCESMTNAPYYMPAARAGA 135
Query: 188 SYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEA 367
+G LVDG+ DGL D Y+ MG AE A+ ITR+ QD +A+ SY++S + +
Sbjct: 136 KFGQTVLVDGVERDGLNDAYDGLAMGVHAEKCARDWDITREQQDNFAIESYQKSQKSQKE 195
Query: 368 KAFVDELVPVPVPQKRGAP-VIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNASTLN 544
F +E+VPV + RG P +DEE R++ EK TVFQKENGTVTA NAS +N
Sbjct: 196 GKFDNEIVPVTIKGFRGKPDTQVTKDEEPARLHVEKLRSARTVFQKENGTVTAANASPIN 255
Query: 545 DGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
DG K N+KP+A I G+ + P DF P
Sbjct: 256 DGAAAVILVSEKVLKEKNLKPLAIIKGWGEAAHQPADFTWAP 297
>UniRef50_P14611 Cluster: Acetyl-CoA acetyltransferase; n=43;
Bacteria|Rep: Acetyl-CoA acetyltransferase - Ralstonia
eutropha (strain ATCC 17699 / H16 / DSM 428 / Stanier
337)(Cupriavidus necator (strain ATCC 17699 / H16 / DSM
428 / Stanier337))
Length = 393
Score = 178 bits (434), Expect = 9e-44
Identities = 95/219 (43%), Positives = 128/219 (58%), Gaps = 3/219 (1%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A I AGLP T+NKVC SG+K++MLAA + G I++AGG E+MS P L
Sbjct: 69 AAIKAGLPAMVPAMTINKVCGSGLKAVMLAANAIMAGDAEIVVAGGQENMSAAPHVLPGS 128
Query: 182 ETSY--GGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAA 355
+ G +LVD ++ DGL DVYN++HMG AEN AK+ ITR+ QDE+AV S ++ A
Sbjct: 129 RDGFRMGDAKLVDTMIVDGLWDVYNQYHMGITAENVAKEYGITREAQDEFAVGSQNKAEA 188
Query: 356 AYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKR-VNFEKFTKLSTVFQKENGTVTAGNA 532
A +A F +E+VPV +PQ++G PV F DE ++ + + L F K GTVTA NA
Sbjct: 189 AQKAGKFDEEIVPVLIPQRKGDPVAFKTDEFVRQGATLDSMSGLKPAFDKA-GTVTAANA 247
Query: 533 STLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDP 649
S LNDG K L + P+A I +A+ DP
Sbjct: 248 SGLNDGAAAVVVMSAAKAKELGLTPLATIKSYANAGVDP 286
>UniRef50_A4G2P1 Cluster: Acetyl-CoA acetyltransferase; n=10;
Bacteria|Rep: Acetyl-CoA acetyltransferase -
Herminiimonas arsenicoxydans
Length = 391
Score = 175 bits (425), Expect = 1e-42
Identities = 93/225 (41%), Positives = 128/225 (56%), Gaps = 2/225 (0%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A I GLP T+NKVC SG+K+ LAAQ +Q G II+AGG E+MS P L+
Sbjct: 69 ASIRGGLPDMVPAFTINKVCGSGLKATHLAAQAIQCGDAHIIIAGGQENMSASPHVLQNS 128
Query: 182 ETSY--GGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAA 355
G +LVD ++ DGL DVYN++HMG AEN AKK I+RQ+QDE+A+ S ++ A
Sbjct: 129 REGIRMGDGKLVDTMIIDGLWDVYNQYHMGTTAENIAKKFGISRQEQDEFALASQHKAEA 188
Query: 356 AYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNAS 535
A A F DE++P+ +P K+GA ++ +++ E L F K+ GTVTAGNAS
Sbjct: 189 AQNAGKFKDEIIPLEIPGKKGAVIVDSDEYIKPGTTLESLAALRPAFSKD-GTVTAGNAS 247
Query: 536 TLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
+NDG L +KP+ARI ++ DP + P
Sbjct: 248 GINDGAAAVIMMTAKKAAELGLKPLARIKAYSSAGVDPAIMGMGP 292
>UniRef50_Q9K6C8 Cluster: Acetyl-CoA acetyltransferase; n=6;
Firmicutes|Rep: Acetyl-CoA acetyltransferase - Bacillus
halodurans
Length = 392
Score = 173 bits (421), Expect = 3e-42
Identities = 92/222 (41%), Positives = 130/222 (58%), Gaps = 3/222 (1%)
Frame = +2
Query: 14 AGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGE--T 187
A LP T+NKVCASGM+S+ LA Q +++G+ +++AGGMESMS P+Y+ +
Sbjct: 72 ADLPWDVRTETINKVCASGMRSVTLADQLIRSGSSKVVVAGGMESMSQAPYYVPKARWGA 131
Query: 188 SYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEA 367
G ++++DG+VFDGLT + HMG TA +L I+R+ QDE+A S++R+ AA A
Sbjct: 132 RMGHVEMIDGMVFDGLTCAFTGVHMGTYGNGTAHELAISREAQDEWAYRSHQRAIAAIGA 191
Query: 368 KAFVDELVPVPVPQKRGAPVIFAEDE-EYKRVNFEKFTKLSTVFQKENGTVTAGNASTLN 544
+E+VPV VPQ++G P++ A DE K + E L VF KE GT+TAGNA +N
Sbjct: 192 GRLEEEIVPVEVPQRKGEPLLVACDEAPRKDTSMESLKNLRPVFGKE-GTITAGNAPGVN 250
Query: 545 DGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
DG K + P+A I G +P DFP P
Sbjct: 251 DGAAAMLLMSEEEAKSAGMAPLAIIEGHTALATEPKDFPKTP 292
>UniRef50_O29070 Cluster: 3-ketoacyl-CoA thiolase; n=2; cellular
organisms|Rep: 3-ketoacyl-CoA thiolase - Archaeoglobus
fulgidus
Length = 424
Score = 164 bits (398), Expect = 2e-39
Identities = 89/228 (39%), Positives = 128/228 (56%), Gaps = 5/228 (2%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A I AG+PK TVNKVC SG+K+I LA ++ G I+AGGMESMSN P+ L +
Sbjct: 98 ASILAGIPKEIPAYTVNKVCGSGLKAIALAYHAVKAGDAKAIIAGGMESMSNAPYALPKA 157
Query: 182 ETSY-----GGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKR 346
Y +++D +V+DGL + + +HMG AEN ++ I+R++QD+ A S+ R
Sbjct: 158 RWGYRMSVTAKDEILDLMVYDGLWEKFYGYHMGMTAENIVERYGISREEQDQLAYESHMR 217
Query: 347 SAAAYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAG 526
+ A + F E+VPV V QK+GA V+ ++ + + EK KL VF+K+ GTVTAG
Sbjct: 218 AVRAIDEGKFAQEIVPVEVKQKKGAVVVDTDEHPRRDTSLEKLAKLPPVFKKD-GTVTAG 276
Query: 527 NASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
NAS +NDG K ++P RI+ A DP + P
Sbjct: 277 NASGVNDGAAAVLVMDEKAAKDYGLEPKVRILAVASAGIDPAYMGLGP 324
>UniRef50_P54810 Cluster: Acetyl-CoA acetyltransferase; n=122;
Bacteria|Rep: Acetyl-CoA acetyltransferase - Paracoccus
denitrificans
Length = 391
Score = 161 bits (391), Expect = 1e-38
Identities = 86/218 (39%), Positives = 124/218 (56%), Gaps = 2/218 (0%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPF--YLK 175
A I GLP+ +N+VC SG++++ LAAQ + G I++AGG ESMS P Y+
Sbjct: 69 AHIKVGLPRESAAWVINQVCGSGLRTVALAAQQVLLGDARIVVAGGQESMSLAPHAAYIA 128
Query: 176 RGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAA 355
G+ G M+++D ++ DGL D +N +HMG AEN A K +I+R +QD++AV S ++ A
Sbjct: 129 PGQ-KMGDMKMLDTMIKDGLWDAFNDYHMGTTAENVAGKWEISRAEQDQFAVASQNKAEA 187
Query: 356 AYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNAS 535
A +A F DE+VPV + ++G V+ A++ E + F KE GTVTAGNAS
Sbjct: 188 AQKAGKFADEIVPVTIKSRKGETVVDADEYIRHGATLEAMENVRPAFSKE-GTVTAGNAS 246
Query: 536 TLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDP 649
LNDG R + P+ARI +A DP
Sbjct: 247 GLNDGAAAVLVMTEDEAARRGLTPLARIASYATAGVDP 284
>UniRef50_Q67RA4 Cluster: Acetyl-CoA acetyltransferase; n=5;
Bacteria|Rep: Acetyl-CoA acetyltransferase -
Symbiobacterium thermophilum
Length = 392
Score = 158 bits (384), Expect = 1e-37
Identities = 87/218 (39%), Positives = 123/218 (56%), Gaps = 2/218 (0%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A + AG+P + VNKVC SG+K++ LAAQ + G +++AGG ESMS P+ + R
Sbjct: 69 ASLKAGIPYTVPVTGVNKVCGSGLKAVALAAQAIMLGDADVVVAGGQESMSGAPYLVPRA 128
Query: 182 ETSY--GGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAA 355
Y G QLVD ++ D LT + HMG AEN A++ I+R+DQD +A S +++ A
Sbjct: 129 RFGYRMGHGQLVDSMIADALTCGWEHVHMGLTAENIAEQFGISREDQDAFAAASQQKAEA 188
Query: 356 AYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNAS 535
A +A F +E+VPV VP ++G V+ A++ E KL F KE GTVTAGNAS
Sbjct: 189 AIKAGRFREEIVPVTVPGRKGDTVVDADEHPRFGTTVEALAKLRPAF-KEGGTVTAGNAS 247
Query: 536 TLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDP 649
+NDG L V+P+A I +A +P
Sbjct: 248 GINDGAAAVVVMSAEKAASLGVRPMAVIRSYAAAGVEP 285
>UniRef50_Q2GA69 Cluster: Acetyl-CoA C-acetyltransferase; n=2;
Alphaproteobacteria|Rep: Acetyl-CoA C-acetyltransferase
- Novosphingobium aromaticivorans (strain DSM 12444)
Length = 392
Score = 153 bits (370), Expect = 5e-36
Identities = 86/219 (39%), Positives = 125/219 (57%), Gaps = 3/219 (1%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYL--K 175
A + AG+P VN++C SG+++I+ AAQG+ G Q I + GG ESMSN P +
Sbjct: 70 AAVNAGIPIEAPAMNVNRLCGSGLQAIVSAAQGIALGEQDIAIGGGAESMSNAPHMVLTA 129
Query: 176 RGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAA 355
R G L+D ++ L D + HMG AEN A++ QITR++QD AV S+KR+AA
Sbjct: 130 RNGQKMGDQVLMDAML-GALHDPFEGIHMGVTAENVAERCQITREEQDSLAVESHKRAAA 188
Query: 356 AYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKR-VNFEKFTKLSTVFQKENGTVTAGNA 532
A A F +++VPV + ++G V+F DE + + E L VF+K+ GTVTAGNA
Sbjct: 189 AIAAGYFKEQIVPVEIKTRKGV-VVFDTDEHVRADASVEAMAGLKPVFKKD-GTVTAGNA 246
Query: 533 STLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDP 649
S +NDG + +KP+ARI+G+ +P
Sbjct: 247 SGINDGAAAVVLASGKAVEEHGLKPMARILGWGHAGVEP 285
>UniRef50_Q1GV21 Cluster: Acetyl-CoA C-acetyltransferase; n=66;
Bacteria|Rep: Acetyl-CoA C-acetyltransferase -
Sphingopyxis alaskensis (Sphingomonas alaskensis)
Length = 395
Score = 151 bits (365), Expect = 2e-35
Identities = 86/226 (38%), Positives = 122/226 (53%), Gaps = 3/226 (1%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLK-- 175
A I AGLPKS TVNKVC SGM+++++ A+ L G+ +I+AGGMESM+N P+ LK
Sbjct: 72 AAIKAGLPKSVQATTVNKVCGSGMQTVIMGAEALAAGSVELIVAGGMESMTNAPYLLKKH 131
Query: 176 RGETSYGGMQLVDGIVFDGLTDVYNKFH-MGNCAENTAKKLQITRQDQDEYAVNSYKRSA 352
R G D + DGL D Y+ MG A++TA Q++RQ D+Y + S R+
Sbjct: 132 RSGARIGHDTAYDHMFLDGLEDAYDAGRAMGTFAQDTADAYQLSRQAMDDYTLTSLSRAK 191
Query: 353 AAYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNA 532
AA AFV E+ PV + +RG V+ DE + +K L F K+ GT+TA +
Sbjct: 192 AAIAEGAFVAEIAPVTISGRRG-DVVVDTDEAPGKAMPDKIPTLKPAFAKD-GTITAATS 249
Query: 533 STLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
S+++DG KP+AR+V A +P DF + P
Sbjct: 250 SSISDGAAAVVLTRQSVADAKGAKPVARLVAHAAHAQEPKDFTVAP 295
>UniRef50_Q62JZ3 Cluster: Beta-ketothiolase; n=107; Bacteria|Rep:
Beta-ketothiolase - Burkholderia mallei (Pseudomonas
mallei)
Length = 394
Score = 149 bits (360), Expect = 8e-35
Identities = 82/225 (36%), Positives = 122/225 (54%), Gaps = 2/225 (0%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLK-- 175
A I G+ + TVN++C SG+++I+ AAQ + G I +AGG E+MS P+ +
Sbjct: 71 AAINGGVAQHAPALTVNRLCGSGLQAIVSAAQNVLLGDADIAVAGGAENMSRAPYSVPAA 130
Query: 176 RGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAA 355
R G +LVD ++ L D + HMG AEN A K ITR QD A+ S++R++
Sbjct: 131 RFGQRMGDAKLVD-MMIGALNDPFQSIHMGVTAENVAAKYGITRDAQDALALESHRRASH 189
Query: 356 AYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNAS 535
A ++ F D+++P+ + ++G V A++ + + FTKL VF KENGTVTAGNAS
Sbjct: 190 ATKSGYFKDQILPIEIASRKGTVVFDADEHVRHDASLDDFTKLKPVFAKENGTVTAGNAS 249
Query: 536 TLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
+ND + KP+AR+V +A DP I P
Sbjct: 250 GINDAAAAVVLMERGVADKRGAKPLARLVSYAHAGVDPAYMGIGP 294
>UniRef50_Q0UU17 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 317
Score = 148 bits (359), Expect = 1e-34
Identities = 82/173 (47%), Positives = 103/173 (59%), Gaps = 3/173 (1%)
Frame = +2
Query: 8 IFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGET 187
I AGLP+S T+NKVCAS +KS++L AQ + TG I++A G ESMSN P YL T
Sbjct: 74 IGAGLPESTVSTTINKVCASSIKSLILGAQTIITGNADIVVAAGTESMSNTPHYLPNLRT 133
Query: 188 S--YGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAY 361
+G LVDG++ DGLTD Y K HMG E A R+ QDEY + SYK++ AA
Sbjct: 134 GAKFGDQPLVDGVLKDGLTDAYKKEHMGLQGEECADDHGFNREQQDEYCIRSYKKAIAAT 193
Query: 362 EAKAFVDELVPVPVPQKRGAPVIFAE-DEEYKRVNFEKFTKLSTVFQKENGTV 517
EA F E+ P+ VPQ RG P I + D+E K N K + + F K NGTV
Sbjct: 194 EAGWFTSEIAPIEVPQGRGKPSITVDKDDEPKNFNEAKTRTVRSAF-KTNGTV 245
>UniRef50_Q8CAY6 Cluster: Acetyl-CoA acetyltransferase, cytosolic;
n=40; cellular organisms|Rep: Acetyl-CoA
acetyltransferase, cytosolic - Mus musculus (Mouse)
Length = 397
Score = 147 bits (356), Expect = 2e-34
Identities = 84/226 (37%), Positives = 123/226 (54%), Gaps = 3/226 (1%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPF--YLK 175
A + AG+P S + +C SG+K++ LAAQ + G I++AGGME+MS P +L+
Sbjct: 73 ASVGAGIPYSVPAWSCQMICGSGLKAVCLAAQSIAMGDSTIVVAGGMENMSKAPHLTHLR 132
Query: 176 RGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAA 355
G G + L D I+ DGLTD ++ +HMG AEN AKK Q++R+ QD+ AV S R+
Sbjct: 133 TG-VRMGEVPLADSILCDGLTDAFHNYHMGITAENVAKKWQVSREAQDKVAVLSQNRAEH 191
Query: 356 AYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKE-NGTVTAGNA 532
A +A F E+VPV V ++G + ++ N E KL F + GTVT NA
Sbjct: 192 AQKAGHFDKEIVPVLVSSRKGLTEVKIDEFPRHGSNLEAMGKLKPYFLTDGTGTVTPANA 251
Query: 533 STLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
S +NDG +R +KP+ARIV ++ +P + P
Sbjct: 252 SGMNDGAAAVVLMKKTEAERRMLKPLARIVSWSQAGVEPSVMGVGP 297
>UniRef50_Q9BWD1 Cluster: Acetyl-CoA acetyltransferase, cytosolic;
n=295; cellular organisms|Rep: Acetyl-CoA
acetyltransferase, cytosolic - Homo sapiens (Human)
Length = 397
Score = 147 bits (355), Expect = 3e-34
Identities = 88/228 (38%), Positives = 125/228 (54%), Gaps = 5/228 (2%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPF--YLK 175
A + AG+P S + +C SG+K++ LA Q + G I++AGGME+MS P YL+
Sbjct: 73 ASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAPHLAYLR 132
Query: 176 RGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAA 355
G G M L D I+ DGLTD ++ HMG AEN AKK Q++R+DQD+ AV S R+
Sbjct: 133 TG-VKIGEMPLTDSILCDGLTDAFHNCHMGITAENVAKKWQVSREDQDKVAVLSQNRTEN 191
Query: 356 AYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKR--VNFEKFTKLSTVFQKE-NGTVTAG 526
A +A F E+VPV V ++G +I + +E+ R N E +KL F + GTVT
Sbjct: 192 AQKAGHFDKEIVPVLVSTRKG--LIEVKTDEFPRHGSNIEAMSKLKPYFLTDGTGTVTPA 249
Query: 527 NASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
NAS +NDG + + P+ARIV ++ +P I P
Sbjct: 250 NASGINDGAAAVVLMKKSEADKRGLTPLARIVSWSQVGVEPSIMGIGP 297
>UniRef50_A1I8P5 Cluster: Acetyl-CoA C-acetyltransferase; n=6;
Bacteria|Rep: Acetyl-CoA C-acetyltransferase -
Candidatus Desulfococcus oleovorans Hxd3
Length = 405
Score = 146 bits (354), Expect = 4e-34
Identities = 81/215 (37%), Positives = 116/215 (53%), Gaps = 3/215 (1%)
Frame = +2
Query: 14 AGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYL---KRGE 184
AGLP + TV++ CAS M+ L AQ + G I G+ESMSN P+ L +RG
Sbjct: 84 AGLPATSFAFTVHQQCASSMRGTELVAQEIMLGKIDIGAVVGVESMSNAPYLLFGARRGY 143
Query: 185 TSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYE 364
G + D ++ GL D +HMG AEN A+K +I+RQ+QDE+A+ S++R+ AA +
Sbjct: 144 RLSDGETVQDSLMIGGLVDALLGYHMGVTAENIAEKYKISRQEQDEWALMSHQRAVAAIQ 203
Query: 365 AKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNASTLN 544
F +E+VPV + K+G + ++ E+ L F+KE GTVTAGNAS LN
Sbjct: 204 KGWFAEEIVPVTIKTKKGDTIFDTDEHPRADTTLERLAALRPAFKKE-GTVTAGNASGLN 262
Query: 545 DGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDP 649
D K + + P+AR+V A G P
Sbjct: 263 DAGAALVLMAATTAKEMGLAPLARVVASAPGSVSP 297
>UniRef50_A4SMV2 Cluster: Acetyl-CoA acetyltransferase; n=1;
Aeromonas salmonicida subsp. salmonicida A449|Rep:
Acetyl-CoA acetyltransferase - Aeromonas salmonicida
(strain A449)
Length = 334
Score = 144 bits (349), Expect = 2e-33
Identities = 81/210 (38%), Positives = 119/210 (56%), Gaps = 2/210 (0%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
AV+ AGLP+S C TVNKVC SGMK++MLAA L+ G I++AGGMESMS P+ L +
Sbjct: 68 AVLKAGLPESVPCTTVNKVCGSGMKAVMLAADSLRLGDTDIVIAGGMESMSRAPYLLDKA 127
Query: 182 ETSY--GGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAA 355
+ + G ++D + DGL D Y MG+ A+ +A + + R D D +A+ S R+ A
Sbjct: 128 RSGFRMGHQSVLDHMFLDGLQDAYEGQLMGHYAQLSADRAGLARSDMDAFAIASLTRALA 187
Query: 356 AYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNAS 535
A ++ AF EL V V G ++ AEDE+ + +K L F K+ GT+TA NAS
Sbjct: 188 AQQSGAFKAELAQVTV----GDTLLLAEDEQPAKARPDKIPHLKPAFSKQ-GTITAANAS 242
Query: 536 TLNDGXXXXXXXXXXXXKRLNVKPIARIVG 625
+++DG +L + P+ + G
Sbjct: 243 SISDGAAALILMRAETAAQLGL-PVLAMAG 271
>UniRef50_P45855 Cluster: Acetyl-CoA acetyltransferase; n=32;
Bacteria|Rep: Acetyl-CoA acetyltransferase - Bacillus
subtilis
Length = 393
Score = 144 bits (348), Expect = 2e-33
Identities = 77/213 (36%), Positives = 125/213 (58%), Gaps = 3/213 (1%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A AG+P S T+NKVCASG++++ L Q ++ I++AGGMESMSN+P+ + G
Sbjct: 69 AARLAGMPWSVPSETLNKVCASGLRAVTLCDQMIRAQDADILVAGGMESMSNIPYAVPAG 128
Query: 182 E--TSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAA 355
G +L D +V+DGLT +++ HM AK+ I+R++QDE+A+ S+ R+A
Sbjct: 129 RWGARMGDGELRDLMVYDGLTCAFDEVHMAVHGNTAAKEYAISRREQDEWALRSHARAAK 188
Query: 356 AYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKR-VNFEKFTKLSTVFQKENGTVTAGNA 532
A + F DE+VPV ++G P + +DE +R + ++ KL+ ++ + G++TAGNA
Sbjct: 189 AADEGKFQDEIVPVNWIGRKGKPNVVDKDEAIRRDTSLDQLAKLAPIYASD-GSITAGNA 247
Query: 533 STLNDGXXXXXXXXXXXXKRLNVKPIARIVGFA 631
+NDG L +P+A I+GF+
Sbjct: 248 PGVNDGAGAFVLMSEEKAAELGKRPLATILGFS 280
>UniRef50_A1WCB0 Cluster: Acetyl-CoA acetyltransferases; n=36;
Proteobacteria|Rep: Acetyl-CoA acetyltransferases -
Acidovorax sp. (strain JS42)
Length = 396
Score = 142 bits (345), Expect = 5e-33
Identities = 78/221 (35%), Positives = 123/221 (55%), Gaps = 3/221 (1%)
Frame = +2
Query: 17 GLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSY- 193
GLP+S T++K+C +GM++ +LA L G++ ++++GGMESM+N P+ LK+G Y
Sbjct: 78 GLPQSTGAVTLSKMCGAGMEATILAHDQLIAGSRDVMVSGGMESMTNAPYLLKKGRGGYR 137
Query: 194 -GGMQLVDGIVFDGLTDVYNKFH-MGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEA 367
G ++ D ++ DGL D Y MG E+ A K TR+ QD +A+ S KR+ A ++
Sbjct: 138 MGHDKVYDHMMLDGLEDAYEAGRSMGTFGEDCAAKYSFTREQQDAFAIESVKRAQQATQS 197
Query: 368 KAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNASTLND 547
AF E+ PV V ++G V + DE + +K L F+K+ GT+TA ++S++ND
Sbjct: 198 GAFATEITPVTVKTRKG-DVTVSVDEGPAKAKLDKIAGLKPAFKKD-GTITAASSSSIND 255
Query: 548 GXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
G ++L KP+A+IV A P F P
Sbjct: 256 GAAALVLMRQSTAQQLGCKPLAKIVAHATHSQAPEWFTTAP 296
>UniRef50_O51136 Cluster: Acetyl-CoA C-acetyltransferase; n=3;
Borrelia burgdorferi group|Rep: Acetyl-CoA
C-acetyltransferase - Borrelia burgdorferi (Lyme disease
spirochete)
Length = 398
Score = 140 bits (339), Expect = 3e-32
Identities = 82/209 (39%), Positives = 116/209 (55%), Gaps = 6/209 (2%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKR----GETSYGGMQLV 211
+VNKVC SG+K++ LA + G I+LAGG+E ++N P+ L R +G +
Sbjct: 82 SVNKVCGSGLKALELAFNSIALGDNDIVLAGGVEDLTNSPYLLPRKIRFDGLKFGNFGIE 141
Query: 212 DGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELV 391
D I D L D N MG AEN ++K +ITR+ QDE+A NS+ ++ A E F DE+
Sbjct: 142 DSIQKDALIDSLNFISMGLTAENLSEKYRITREMQDEFAYNSHVKALKARELGYFEDEIY 201
Query: 392 PVPV-PQKRGAPVIFAEDEEYK-RVNFEKFTKLSTVFQKENGTVTAGNASTLNDGXXXXX 565
P+ V +K + V + DEE + + K L+ VF KE+GTVTAGN+S+LNDG
Sbjct: 202 PLTVFDKKTNSSVTISSDEEIRDNLTLNKLASLNPVF-KESGTVTAGNSSSLNDGACFLI 260
Query: 566 XXXXXXXKRLNVKPIARIVGFADGECDPI 652
K L + P+A I GF DP+
Sbjct: 261 LASEERVKSLGLSPLAYIGGFKSVGLDPL 289
>UniRef50_A2DM80 Cluster: Acetyl-CoA acyltransferases family
protein; n=2; Trichomonas vaginalis G3|Rep: Acetyl-CoA
acyltransferases family protein - Trichomonas vaginalis
G3
Length = 387
Score = 139 bits (337), Expect = 5e-32
Identities = 74/226 (32%), Positives = 116/226 (51%), Gaps = 3/226 (1%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A + AG P + C +NKVC S MK++ L ++ G ++ GG E+MS P L+
Sbjct: 69 AALAAGFPVTTPCTLINKVCCSSMKALQLGVLEIKAGDSQAVMIGGFENMSRCPHLLQNS 128
Query: 182 ETSY--GGMQLVDGIVFDGLTDV-YNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSA 352
Y G +D ++ DGL D YN+ MG + +K I+R+DQD +A+ S+ R+
Sbjct: 129 RNGYRLGNFSAIDSLINDGLWDAKYNQM-MGQLVDVLNEKQGISREDQDRFAIQSFDRAT 187
Query: 353 AAYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNA 532
A+E AF ++ VP+ + DE ++ EK +L F GT+TA NA
Sbjct: 188 KAWEEHAFDEQNVPIKTSSGE-----YKMDESILKLRREKVPQLKPAFSP-TGTITAANA 241
Query: 533 STLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
S+++DG K N+KPIA+I+ + + DP +FP+ P
Sbjct: 242 SSISDGAAAVAICSSEFAKEHNLKPIAKIISYGEAGVDPSEFPLAP 287
>UniRef50_Q236D4 Cluster: Acetyl-CoA acyltransferases family protein;
n=1; Tetrahymena thermophila SB210|Rep: Acetyl-CoA
acyltransferases family protein - Tetrahymena thermophila
SB210
Length = 1352
Score = 139 bits (336), Expect = 6e-32
Identities = 70/221 (31%), Positives = 116/221 (52%), Gaps = 2/221 (0%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYL--K 175
A + G+ C TVNK C+SG+KS+++ A + G ++ GG ESMSNVPFY+ +
Sbjct: 1028 AALLGGVDIEVPCSTVNKACSSGLKSVIVGANSINVGYNQCVVTGGFESMSNVPFYMYQQ 1087
Query: 176 RGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAA 355
R +G +L+DGI+ DG+ D Y++ +G AE K ++ +Q D A+ SY+R+
Sbjct: 1088 RRGKQFGDSKLLDGILNDGVQDKYSEQPLGYLAEQLCKNMKFQKQTVDAVAIASYERAIE 1147
Query: 356 AYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNAS 535
A + ++ P+ +G +D ++ + EK T F + G +T N S
Sbjct: 1148 ARDNGFLAKQISPIQYHDGQGKVFSIKDDANLEQYDQEKILN-DTAFYAKEGIITQSNQS 1206
Query: 536 TLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDF 658
DG K+LN+KP+ARI+G+ E +P+++
Sbjct: 1207 NFADGAATLILMSEEMVKQLNIKPLARILGYQQVEKEPLEY 1247
>UniRef50_Q577L1 Cluster: PhbA-2, acetyl-CoA acetyltransferase;
n=72; Proteobacteria|Rep: PhbA-2, acetyl-CoA
acetyltransferase - Brucella abortus
Length = 399
Score = 137 bits (332), Expect = 2e-31
Identities = 84/226 (37%), Positives = 119/226 (52%), Gaps = 3/226 (1%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A + AGLP TVNK+C SGMK+ MLA + G+ +I+AGGMESM+N P+ L +
Sbjct: 72 ASLKAGLPLGTGATTVNKMCGSGMKAAMLAHDLILAGSADVIVAGGMESMTNAPYLLPKA 131
Query: 182 ETSY--GGMQLVDGIVFDGLTDVYNKFH-MGNCAENTAKKLQITRQDQDEYAVNSYKRSA 352
Y G Q++D + DGL D Y+K MG AE+ A+ Q TR+ QD +A++S R+
Sbjct: 132 RGGYRMGHGQVLDHMFLDGLEDAYDKGRLMGTFAEDCAEAYQFTREAQDAFAISSLTRAQ 191
Query: 353 AAYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNA 532
A + F E+ PV V R A V + DE+ + +K L F +E GTVTA N+
Sbjct: 192 NAIKDGLFAAEITPVKVKSGR-AEVEVSIDEQPSKAKLDKIPTLRPAF-REGGTVTAANS 249
Query: 533 STLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
S+++DG ++ + P A I G A P F P
Sbjct: 250 SSISDGAAALLLMRASEAEKRGLTPRAVITGHATYADKPNLFSTAP 295
>UniRef50_A1SHM4 Cluster: Acetyl-CoA acetyltransferases; n=8;
Bacteria|Rep: Acetyl-CoA acetyltransferases -
Nocardioides sp. (strain BAA-499 / JS614)
Length = 396
Score = 137 bits (332), Expect = 2e-31
Identities = 77/211 (36%), Positives = 118/211 (55%), Gaps = 5/211 (2%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A + G+P + T+NKVC SGM +I LA Q ++ G I++AGGMESM+ P L +
Sbjct: 69 ASVKGGIPMNVPAITINKVCLSGMNAIALADQLIRAGEHEIVVAGGMESMTQAPHLLPKS 128
Query: 182 ET--SYGGMQLVDGIVFDGLTDVYNKFHMGNCAE--NTAKKLQITRQDQDEYAVNSYKRS 349
YG LVD + +D L D + MG E NT + ++TR++QD ++ S++ +
Sbjct: 129 REGFKYGDTALVDSMAYDALYDQFTDQPMGTLTEACNTGAR-ELTREEQDAFSARSHQLA 187
Query: 350 AAAYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYK-RVNFEKFTKLSTVFQKENGTVTAG 526
AAA++ F DE+VPV +PQ++G PV+ A DE + E KL F K+ GT+TAG
Sbjct: 188 AAAWKNGVFDDEVVPVEIPQRKGDPVVIANDEGIRGDTTAESLGKLRPAFSKD-GTITAG 246
Query: 527 NASTLNDGXXXXXXXXXXXXKRLNVKPIARI 619
++S ++DG + L + +A I
Sbjct: 247 SSSQISDGACAVVVMSKAKAEELGLTWLAEI 277
>UniRef50_P42765 Cluster: 3-ketoacyl-CoA thiolase, mitochondrial;
n=62; cellular organisms|Rep: 3-ketoacyl-CoA thiolase,
mitochondrial - Homo sapiens (Human)
Length = 397
Score = 136 bits (330), Expect = 3e-31
Identities = 78/220 (35%), Positives = 118/220 (53%), Gaps = 2/220 (0%)
Frame = +2
Query: 17 GLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLK--RGETS 190
G+PK T+N++C SG +SI+ Q + ++L GG ESMS P+ ++ R T
Sbjct: 78 GIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQAPYCVRNVRFGTK 137
Query: 191 YGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAK 370
G ++ ++ LTD + + M AEN A K +I+R++ D+YA+ S +R AA +A
Sbjct: 138 LGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYALQSQQRWKAANDAG 197
Query: 371 AFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNASTLNDG 550
F DE+ P+ V K+G + ++ + E+ KL VF+K+ GTVTAGNAS + DG
Sbjct: 198 YFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFKKD-GTVTAGNASGVADG 256
Query: 551 XXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
K+ N P+ARIVG+ CDP I P
Sbjct: 257 AGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGP 296
>UniRef50_A1SPA4 Cluster: Acetyl-CoA acetyltransferases; n=6;
Bacteria|Rep: Acetyl-CoA acetyltransferases -
Nocardioides sp. (strain BAA-499 / JS614)
Length = 397
Score = 136 bits (329), Expect = 5e-31
Identities = 83/215 (38%), Positives = 112/215 (52%), Gaps = 3/215 (1%)
Frame = +2
Query: 14 AGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSY 193
AGLP TVN++C SG++++ AA ++ GA + LAGG ESM+ +PFY Y
Sbjct: 80 AGLPDRTPAYTVNRLCGSGLQAVWSAAMQIRWGAAELALAGGDESMTRMPFYDFGARAGY 139
Query: 194 --GGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEA 367
G LVDG V LTD ++ HMG AE A+K +TR +QDE+A S +R+A
Sbjct: 140 KLGDRALVDGTVMM-LTDPFHGIHMGVTAERVAEKYGVTRAEQDEFAAESQRRAATPEAR 198
Query: 368 KAFVDELVPVPVPQKRGAPVIFAEDEEYK-RVNFEKFTKLSTVFQKENGTVTAGNASTLN 544
AF +E+VPV V +R P +EDE K E +L F E GTVTAGNAS +N
Sbjct: 199 AAFAEEIVPVEVGGRR--PFTASEDEHPKPDTTVETLARLRPAF-AEGGTVTAGNASGIN 255
Query: 545 DGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDP 649
DG + P+ +V A +P
Sbjct: 256 DGGAAVVVASSRVAADRGLTPLVELVSVATAALEP 290
>UniRef50_Q8ESF0 Cluster: Thiolase B; n=5; Bacteria|Rep: Thiolase B
- Oceanobacillus iheyensis
Length = 394
Score = 136 bits (328), Expect = 6e-31
Identities = 86/230 (37%), Positives = 126/230 (54%), Gaps = 7/230 (3%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A + AG+P+ TVN++CASG++++ Q + + I++AGG ESMS P YL+
Sbjct: 70 AALRAGIPEQVTAFTVNRLCASGIQAVTSGVQQILSNQADIVVAGGAESMSRSPIYLRN- 128
Query: 182 ETSYGGMQ--LVDGIVFDGLT--DVYNK-FHMGNCAENTAKKLQITRQDQDEYAVNSYKR 346
T +GG + +VD + G ++Y K MG AEN A+K +I+R+DQD +A+ S R
Sbjct: 129 -TRFGGDRTTIVDSNLEAGQQPPEIYGKSLSMGITAENVARKYKISREDQDAFALESQHR 187
Query: 347 SAAAYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRV--NFEKFTKLSTVFQKENGTVT 520
+ A E F E+ P+ V +K+ V FA D EY R+ + EK L VF+ + GTVT
Sbjct: 188 AKKAIETGRFKKEIAPIEVKEKKQTSV-FAVD-EYPRLDTSLEKLASLKPVFEAD-GTVT 244
Query: 521 AGNASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
AGNA NDG K L +KP+ARI+ ++ P I P
Sbjct: 245 AGNACGRNDGASALVIMKESRAKHLGLKPLARIIDWSTAGVSPEMMGIGP 294
>UniRef50_A0NJ40 Cluster: Acetyl-CoA C-acetyltransferase-like
protein; n=2; Oenococcus oeni|Rep: Acetyl-CoA
C-acetyltransferase-like protein - Oenococcus oeni ATCC
BAA-1163
Length = 386
Score = 136 bits (328), Expect = 6e-31
Identities = 83/206 (40%), Positives = 111/206 (53%), Gaps = 2/206 (0%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A AG+P S T+N VC SG+ SI LAA+ + G II+AGGMESMSN PF LK
Sbjct: 71 AARLAGIPFSIPSTTINDVCGSGLHSINLAAKLIAGGFDDIIVAGGMESMSNAPFLLKNH 130
Query: 182 ETSY--GGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAA 355
+ G ++ D ++ D L D FHMG AEN A++ I+RQ D YA+ S+ R+
Sbjct: 131 RFGHKLGNEKIDDTLLRDALIDPIGNFHMGITAENIAERYSISRQSMDRYALESHSRAVR 190
Query: 356 AYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNAS 535
A + F DE+V V ++ AP + E+ +KL VF KE G VTAGNAS
Sbjct: 191 AEKKGLFNDEIVAVDQVKQDQAP--------RADTSLEQLSKLKAVF-KEGGKVTAGNAS 241
Query: 536 TLNDGXXXXXXXXXXXXKRLNVKPIA 613
+NDG + LN+ P+A
Sbjct: 242 GINDGAAGVILASERKVEELNLNPLA 267
>UniRef50_Q4TEZ1 Cluster: Chromosome undetermined SCAF4980, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF4980,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 159
Score = 135 bits (326), Expect = 1e-30
Identities = 76/159 (47%), Positives = 96/159 (60%), Gaps = 25/159 (15%)
Frame = +2
Query: 140 MESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHM------------------- 262
MESMSNVP+ + R YGG+++ D IV DGLTDVYNKFHM
Sbjct: 1 MESMSNVPYVMSRESPVYGGVKMEDLIVKDGLTDVYNKFHMVTTSRLSCCRSPTFPLRSA 60
Query: 263 ------GNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAP 424
GNCAENTAK+ +I+R++QD YAV SY RS AA++A E+V V VPQ+ A
Sbjct: 61 VAPRHQGNCAENTAKQSRISREEQDAYAVGSYSRSQAAHQAGVLAKEIVAVSVPQRGKAD 120
Query: 425 VIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNASTL 541
V+ +EDEE++RV+F K L VFQKENG+ A L
Sbjct: 121 VLVSEDEEWRRVDFSKVPNLKPVFQKENGSAAPAPAVAL 159
>UniRef50_Q6KYW2 Cluster: Acetyl-CoA acetyltransferase; n=4;
Thermoplasmatales|Rep: Acetyl-CoA acetyltransferase -
Picrophilus torridus
Length = 388
Score = 134 bits (323), Expect = 2e-30
Identities = 82/229 (35%), Positives = 118/229 (51%), Gaps = 6/229 (2%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A AGLP TVN VCASGM ++ AA+ + G + +I+AGGME+MS P L
Sbjct: 69 AAYHAGLPFGVTKYTVNVVCASGMLAVESAAREIMLGERDLIVAGGMENMSMSPLLLSSE 128
Query: 182 ------ETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYK 343
+ Y M++ D ++ DGL D HMG AE +A+K +TR+D D Y+V S +
Sbjct: 129 FRWGPKQLLYKNMKIEDSMLVDGLIDAMYYEHMGVSAERSARKYNLTREDADSYSVQSQE 188
Query: 344 RSAAAYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTA 523
R+ A E+ F +E+VPV + DE ++ + KL+ F ++ G +TA
Sbjct: 189 RAIRATESGEFRNEIVPVNDIDR---------DEGLRKTTMKDLEKLNPAFDRD-GILTA 238
Query: 524 GNASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
GN+S L+DG ++KPIARI G+ DP DF P
Sbjct: 239 GNSSQLSDGASALVMASEKAINEYDLKPIARITGYESASLDPRDFVEAP 287
>UniRef50_Q43974 Cluster: Beta-ketoadipyl-CoA thiolase; n=274;
Bacteria|Rep: Beta-ketoadipyl-CoA thiolase -
Acinetobacter sp. (strain ADP1)
Length = 401
Score = 133 bits (322), Expect = 3e-30
Identities = 74/214 (34%), Positives = 116/214 (54%), Gaps = 7/214 (3%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
+ + AGLP TVN++C S + +I +AA+ ++ G +I+AGG+ESMS P+ + +
Sbjct: 71 SALLAGLPVEVPATTVNRLCGSSLDAIAMAARAIKAGEAHLIIAGGVESMSRAPYVMGKS 130
Query: 182 ETSYGGMQLVDG------IVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYK 343
E ++G Q ++ + L +Y M AEN A++ I R+DQD++A S +
Sbjct: 131 EGAFGRTQKIEDTTMGWRFINPKLKAMYGVDTMPQTAENVAEQFGIQREDQDQFAYTSQQ 190
Query: 344 RSAAAYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYK-RVNFEKFTKLSTVFQKENGTVT 520
R+AAA F E+VPV +PQ++G PV+ DE + E KL V + E G+VT
Sbjct: 191 RTAAAQAKGYFAKEIVPVTIPQRKGEPVVIDTDEHPRASTTLEGLAKLKGVVKPE-GSVT 249
Query: 521 AGNASTLNDGXXXXXXXXXXXXKRLNVKPIARIV 622
AGNAS +NDG + +K A+I+
Sbjct: 250 AGNASGINDGAAAVLIASDEAVAQYQLKARAKII 283
>UniRef50_Q8D6N4 Cluster: Acetyl-CoA acetyltransferase; n=14;
Vibrionaceae|Rep: Acetyl-CoA acetyltransferase - Vibrio
vulnificus
Length = 405
Score = 133 bits (321), Expect = 4e-30
Identities = 79/225 (35%), Positives = 113/225 (50%), Gaps = 2/225 (0%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLK-- 175
A + A L S C TVNKVC SGMK++MLA L+ G + ++AGGMESM+N P+ LK
Sbjct: 70 AALKAELGYSTPCTTVNKVCGSGMKAVMLAYDQLKAGDKCCMIAGGMESMTNAPYLLKES 129
Query: 176 RGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAA 355
R G D + DGL D Y MG A+ A KL TR+ D +A+ S +R+
Sbjct: 130 RSGMRMGHKTTFDHMFLDGLQDAYEGHLMGVYAQQIADKLNYTREQMDTWAIQSAQRATQ 189
Query: 356 AYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNAS 535
A F +E+ P+ + + + + DE + +K KL F +NGTVTA N+S
Sbjct: 190 AQHEAQFKEEITPIFLEGR--SSMTLDHDEHPTTIQLDKIPKLKPAF-ADNGTVTAANSS 246
Query: 536 TLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
+ DG ++ + P+A I G A P +F + P
Sbjct: 247 AIADGAAALILADGDWAEKQGLTPLAIIRGHASHARLPAEFTVAP 291
>UniRef50_Q5UX35 Cluster: Acetyl-coA acetyltransferase; n=1;
Haloarcula marismortui|Rep: Acetyl-coA acetyltransferase
- Haloarcula marismortui (Halobacterium marismortui)
Length = 387
Score = 132 bits (319), Expect = 7e-30
Identities = 79/223 (35%), Positives = 114/223 (51%), Gaps = 3/223 (1%)
Frame = +2
Query: 5 VIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLK--R 178
V+ + LP T+N+ SG+++I AA ++ G + LAGGMESMSN P+ + R
Sbjct: 70 VVESSLPDDVAATTLNEASGSGLRAITTAADRIEAGRASVCLAGGMESMSNAPYLVPDMR 129
Query: 179 GETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAA 358
G +G +LVD +++D L D HMG E A + I+R+ QDEYA S R+ A
Sbjct: 130 GGRRHGNSELVDAMIWDSLWDKQYDAHMGTLTEELAAEHDISREAQDEYARRSNHRAGEA 189
Query: 359 YEAKAFVDELVPVPVPQKRGAPVIFAEDE-EYKRVNFEKFTKLSTVFQKENGTVTAGNAS 535
++ F +ELVPV A + EDE + +K L F + GT+TAGNAS
Sbjct: 190 IQSGQFTEELVPVET-----ADGLVTEDEGPHPDTTVDKLAALPPAF-ADGGTITAGNAS 243
Query: 536 TLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPI 664
L+DG KR + P+A + +A DP +F I
Sbjct: 244 KLSDGAGAVVLADAETVKREGLGPMAHVEDYAVAYRDPSEFSI 286
>UniRef50_Q1VJ45 Cluster: Acetyl-CoA acetyltransferase; n=1;
Psychroflexus torquis ATCC 700755|Rep: Acetyl-CoA
acetyltransferase - Psychroflexus torquis ATCC 700755
Length = 371
Score = 132 bits (318), Expect = 1e-29
Identities = 78/221 (35%), Positives = 119/221 (53%), Gaps = 2/221 (0%)
Frame = +2
Query: 14 AGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPF-YLKR-GET 187
+G+ +S VN+VC SGM++ + A+ + T +++AGG ESMS YL R GE
Sbjct: 63 SGMSQSSFAYVVNQVCGSGMRAAIEASLKIFTQESDLVIAGGQESMSRARHAYLSRTGEK 122
Query: 188 SYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEA 367
G +D ++ DGLTD +++ HMG AEN A+K +TRQ+QD+YA SY ++ A +
Sbjct: 123 KLGNNIFIDTLIHDGLTDAFSQEHMGITAENVARKYNVTRQEQDQYAYGSYSKAYKALKN 182
Query: 368 KAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNASTLND 547
K F +EL + +DE K + L VF+K+ G+V+AGNAS+LND
Sbjct: 183 KYFKNELCQTTL-----------KDEVRADTTLVKLSHLKPVFKKK-GSVSAGNASSLND 230
Query: 548 GXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
G K +KP+A+I+ ++ +P I P
Sbjct: 231 GAAFLALASSDYIKANKIKPLAKILSWSSSAGNPDYMGITP 271
>UniRef50_Q835L3 Cluster: Acetyl-CoA
acetyltransferase/hydroxymethylglutaryl-CoA reductase,
degradative; n=86; cellular organisms|Rep: Acetyl-CoA
acetyltransferase/hydroxymethylglutaryl-CoA reductase,
degradative - Enterococcus faecalis (Streptococcus
faecalis)
Length = 803
Score = 128 bits (308), Expect = 2e-28
Identities = 78/222 (35%), Positives = 119/222 (53%), Gaps = 1/222 (0%)
Frame = +2
Query: 8 IFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGET 187
I +GL TVN+VC SGMK+++LA Q +Q G +++AGG+E+MS P +
Sbjct: 71 INSGLSHEIPAMTVNEVCGSGMKAVILAKQLIQLGEAEVLIAGGIENMSQAPKLQRFNYE 130
Query: 188 SYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEA 367
+ +++DGLTD ++ MG AEN A+K +TR++QD+++V+S ++A A
Sbjct: 131 TESYDAPFSSMMYDGLTDAFSGQAMGLTAENVAEKYHVTREEQDQFSVHSQLKAAQAQAE 190
Query: 368 KAFVDELVPVPVPQKRGAPVIFAEDEEYK-RVNFEKFTKLSTVFQKENGTVTAGNASTLN 544
F DE+ P+ V + + +DE + + EK L TVF KE+GTVTAGNAST+N
Sbjct: 191 GIFADEIAPLEV-----SGTLVEKDEGIRPNSSVEKLGTLKTVF-KEDGTVTAGNASTIN 244
Query: 545 DGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
DG + + +A I + DP I P
Sbjct: 245 DGASALIIASQEYAEAHGLPYLAIIRDSVEVGIDPAYMGISP 286
>UniRef50_Q0AYU4 Cluster: Acetyl-CoA C-acetyltransferase; n=4;
Clostridiales|Rep: Acetyl-CoA C-acetyltransferase -
Syntrophomonas wolfei subsp. wolfei (strain Goettingen)
Length = 403
Score = 128 bits (308), Expect = 2e-28
Identities = 72/207 (34%), Positives = 108/207 (52%), Gaps = 2/207 (0%)
Frame = +2
Query: 8 IFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGET 187
I AGLP VN+ CASGM+++ +A +Q G + L G+ESM+N P+ + +
Sbjct: 75 IAAGLPVRSNACNVNQNCASGMRALDVALTHIQLGKTDVALVVGVESMTNAPYMIPKARM 134
Query: 188 SY--GGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAY 361
Y G + D ++ DGL D HMG AEN A+K ITR++ D+ A+ S++R+ A
Sbjct: 135 GYRMGPGSIEDAMLHDGLIDRLVPGHMGVTAENIAEKYGITREECDQLALASHQRATRAT 194
Query: 362 EAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNASTL 541
+ F E+VPV + K+G + ++ N E KL + F K+ G VTA NAS L
Sbjct: 195 QDGTFQREIVPVELKSKKGVKIYDKDEHMIPDANLEAMAKLPSAF-KKGGVVTAANASGL 253
Query: 542 NDGXXXXXXXXXXXXKRLNVKPIARIV 622
ND L VKP+ +++
Sbjct: 254 NDAAAAVIIMSKAKALELGVKPLMKLI 280
>UniRef50_A5UXI0 Cluster: Acetyl-CoA acetyltransferase; n=5;
cellular organisms|Rep: Acetyl-CoA acetyltransferase -
Roseiflexus sp. RS-1
Length = 391
Score = 127 bits (307), Expect = 2e-28
Identities = 87/232 (37%), Positives = 123/232 (53%), Gaps = 9/232 (3%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A++ AGLP TVN+ CASG+++I LAAQ + +G +++AGG ESMS VP
Sbjct: 72 ALLRAGLPTDVPGQTVNRFCASGLQTIALAAQQVMSGMGDVVVAGGAESMSAVPM----- 126
Query: 182 ETSYGGMQLVDGIVFDGLT-DVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAA 358
GG ++ DVY MG AEN A++ +++R+DQD +A+ S++R+ AA
Sbjct: 127 ----GGHHFAPNPAMAEMSPDVY--LGMGLTAENVARRYEVSREDQDAFALRSHQRAIAA 180
Query: 359 YEAKAFVDELVPVPVP-------QKRGAPVIFAEDEEYKR-VNFEKFTKLSTVFQKENGT 514
+A F DE+VP+ V + + + +IF DE +R + E KL VF NGT
Sbjct: 181 IDAGLFKDEIVPIEVEHVWFENGRVQRSTMIFDTDEGPRRDTSAEALAKLKPVF-AINGT 239
Query: 515 VTAGNASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
VTAGN+S +DG L VKP+AR V FA P I P
Sbjct: 240 VTAGNSSQTSDGAAAVVVMSREKADALGVKPLARFVSFAVAGVPPEIMGIGP 291
>UniRef50_A6CQ12 Cluster: Acetyl-CoA acetyltransferase; n=1;
Bacillus sp. SG-1|Rep: Acetyl-CoA acetyltransferase -
Bacillus sp. SG-1
Length = 391
Score = 126 bits (305), Expect = 4e-28
Identities = 76/220 (34%), Positives = 117/220 (53%), Gaps = 4/220 (1%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A + AG + T+ + CASGM++I+ A +QTG I+LAGG+E+MS+ P+ +K
Sbjct: 69 AALLAGFSDTTTGYTIQRQCASGMQAIISAYMQIQTGMSDIVLAGGVEAMSSSPYVMKGH 128
Query: 182 ETSYGGMQLVDG----IVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRS 349
G +L G V++ L D + MG AEN A+ ITR+DQDE A S++R+
Sbjct: 129 RW---GQRLQHGEIRDTVWEALEDPIHGIMMGETAENLAEIHNITREDQDELAKLSHERA 185
Query: 350 AAAYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGN 529
A E F ++VP+ V ++ I ++ + EK + L F ++ GTVTAGN
Sbjct: 186 VKAAEEGYFDSQIVPIEVKSRKETKTISKDESPRAGLTMEKLSGLKPAF-RQGGTVTAGN 244
Query: 530 ASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDP 649
+S+LNDG ++ +KP+A I G + DP
Sbjct: 245 SSSLNDGGAAVILMSEEEAEKRGLKPLASISGCSVAGVDP 284
>UniRef50_Q74IF9 Cluster: Acetyl-CoA acetyltransferase; n=5;
Lactobacillus|Rep: Acetyl-CoA acetyltransferase -
Lactobacillus johnsonii
Length = 388
Score = 124 bits (299), Expect = 2e-27
Identities = 73/212 (34%), Positives = 109/212 (51%)
Frame = +2
Query: 14 AGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSY 193
+GLP+S +V+ VC S +K++ A + G I + GG ESM+N P L + +
Sbjct: 74 SGLPESVVGTSVDDVCGSSLKALRFAQGQMLLGDSQIAIVGGAESMTNAPLLLDKSKKHD 133
Query: 194 GGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKA 373
D ++ DG+ D Y++ MG AEN A K ITRQD DE+A +S+ ++ AA E
Sbjct: 134 ENPAYQDSLMIDGIGDAYSRKPMGITAENVADKYHITRQDMDEFARDSHAKAYAAQENDW 193
Query: 374 FVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNASTLNDGX 553
F +E P+ + V+ ++ + E +L VF KENG VTAGN+S L DG
Sbjct: 194 FKEEYAPIEL----DGHVLDHDETIRPDSSLEALGQLKPVF-KENGRVTAGNSSPLTDGA 248
Query: 554 XXXXXXXXXXXKRLNVKPIARIVGFADGECDP 649
LN+ P+A + +A+ CDP
Sbjct: 249 SMLLLSNQQKLDELNLTPLAYLGAYAEIGCDP 280
>UniRef50_Q9RRK9 Cluster: Acetyl-CoA acetyltransferase; n=12;
Bacteria|Rep: Acetyl-CoA acetyltransferase - Deinococcus
radiodurans
Length = 399
Score = 124 bits (298), Expect = 3e-27
Identities = 84/231 (36%), Positives = 121/231 (52%), Gaps = 8/231 (3%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A + AGLP S TVN+ C+SG+++I +AA +QTG ++LAGG+ESMS +P G
Sbjct: 71 AALRAGLPDSVGGVTVNRFCSSGLQTIAMAAAAIQTGQADVMLAGGVESMSMLPM---SG 127
Query: 182 ETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAY 361
LV D Y MG AEN A K ++R+DQD++A S++++AAA
Sbjct: 128 HNPSPNPDLV-----DDRPGAY--IGMGMTAENVAAKYGVSREDQDKFAYASHQKAAAAQ 180
Query: 362 EAKAFVDELVPVPV-------PQKRGAPVIFAEDEEYKR-VNFEKFTKLSTVFQKENGTV 517
+A F E+VPVPV + + V+F +DE +R N E K+ F K G+V
Sbjct: 181 DAGKFDAEIVPVPVRKDSVKGTKLKSDTVMFDKDELIRRDANLEDMAKVRPAF-KLGGSV 239
Query: 518 TAGNASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
+A N+S +DG + L VKP+A+ +GFA P I P
Sbjct: 240 SAANSSPFSDGAAAVLLMSGEKAQELGVKPLAKFIGFAVAGVAPEVMGIGP 290
>UniRef50_Q8ESG3 Cluster: Acetyl-CoA acetyltransferase; n=4;
Firmicutes|Rep: Acetyl-CoA acetyltransferase -
Oceanobacillus iheyensis
Length = 391
Score = 122 bits (294), Expect = 8e-27
Identities = 75/211 (35%), Positives = 113/211 (53%), Gaps = 2/211 (0%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIV 223
T+++ C SG+ +I+LA Q +Q+G I +AGGMESMS P+ + R + ++ + I
Sbjct: 84 TIDRQCGSGINAIVLAQQAIQSGMGDIYVAGGMESMSRAPYLMDRPDKAFSPVPPT--IR 141
Query: 224 FDGLTDVY-NKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVP 400
L+ + MG AEN AKK I+R++QDEYA++S +R A F +++VP+
Sbjct: 142 KSKLSPEHIGDPPMGITAENLAKKYNISREEQDEYALSSQQRMEEAMREGRFKEQIVPIS 201
Query: 401 VPQKRGAPVIFAEDEEYK-RVNFEKFTKLSTVFQKENGTVTAGNASTLNDGXXXXXXXXX 577
VP ++ A ++F DE + E KL F KE GTVTAG++S LND
Sbjct: 202 VPLRKEAAIVFDTDEHPRPNSTMEGLKKLPPAFVKE-GTVTAGSSSGLNDAASALVIMSR 260
Query: 578 XXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
+ LN+ P+A + A DP I P
Sbjct: 261 EKAEELNLTPLAIVRNAAVAGVDPNVMGIGP 291
>UniRef50_Q0SDR4 Cluster: Acetyl-CoA C-acetyltransferase; n=31;
Bacteria|Rep: Acetyl-CoA C-acetyltransferase -
Rhodococcus sp. (strain RHA1)
Length = 411
Score = 121 bits (292), Expect = 1e-26
Identities = 74/228 (32%), Positives = 121/228 (53%), Gaps = 9/228 (3%)
Frame = +2
Query: 14 AGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLK------ 175
AG+P + +++ C SG+++++ AA +QTG +++AGG+ESMS +Y +
Sbjct: 81 AGMPVTVPGQQLDRRCGSGLQAVLDAAMRVQTGIAELVIAGGVESMSRAEYYTESMRWGA 140
Query: 176 RGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAA 355
+G + +L G V G + M AEN +K I+R +QDE AV+S++R+ A
Sbjct: 141 KGAPAVLHDRLARGRVTAGGRNYPVPGGMLETAENLRRKYDISRLEQDELAVSSHQRAVA 200
Query: 356 AYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKR-VNFEKFTKLSTVF--QKENGTVTAG 526
A ++ F +E+VPV VP ++G P + DE + E +L + + TVTAG
Sbjct: 201 AIDSGKFAEEIVPVEVPVRKGDPQVVDRDEHPRAGTTIESLARLRPIMGGTDPDATVTAG 260
Query: 527 NASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
NAS NDG +RL ++P+AR+V +A +P + I P
Sbjct: 261 NASGQNDGAAACLVTTRAQAERLGLRPLARLVTWAVAGVEPSEMGIGP 308
>UniRef50_Q21BM7 Cluster: Acetyl-CoA C-acetyltransferase; n=1;
Rhodopseudomonas palustris BisB18|Rep: Acetyl-CoA
C-acetyltransferase - Rhodopseudomonas palustris (strain
BisB18)
Length = 389
Score = 116 bits (280), Expect = 4e-25
Identities = 72/224 (32%), Positives = 114/224 (50%), Gaps = 1/224 (0%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A + AGLP S T+++ CA+ + ++ A + G +I+AGG+ES S + +++
Sbjct: 68 AALEAGLPVSVGGITLDRQCAASLNALAYGAMQIMAGFADVIVAGGVESDSRRTYSMEKS 127
Query: 182 ETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAY 361
E +Y + + D MG AEN A++ ++TRQ+ DE++V S+ ++AA+
Sbjct: 128 EIAYS-VAPPKWVDIHTSPDSIGNPPMGITAENVAERWKLTRQELDEFSVRSHVLASAAW 186
Query: 362 EAKAFVDELVPVPVPQKRGAPVIFAEDEEYK-RVNFEKFTKLSTVFQKENGTVTAGNAST 538
EA F DE+VP+ V +G + DE + E + L VF K NG VTAGN+S
Sbjct: 187 EAGRFQDEVVPIEVKGPKGKKTVVDRDESVRPDCTLESLSGLRAVF-KPNGVVTAGNSSP 245
Query: 539 LNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
++DG L V+P+A G+A DP I P
Sbjct: 246 MSDGGGAIVIVDRDTATSLGVEPLAMFRGYAVAGVDPNVMGIGP 289
>UniRef50_A6T953 Cluster: Putative acetyl-CoA acetyltransferase;
n=1; Klebsiella pneumoniae subsp. pneumoniae MGH
78578|Rep: Putative acetyl-CoA acetyltransferase -
Klebsiella pneumoniae subsp. pneumoniae MGH 78578
Length = 396
Score = 116 bits (278), Expect = 7e-25
Identities = 66/212 (31%), Positives = 112/212 (52%), Gaps = 2/212 (0%)
Frame = +2
Query: 14 AGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSY 193
AG+P+ +VN+ C SG++++ LQ+G +++A G E+M+ +P+YL++ Y
Sbjct: 76 AGIPQESTAYSVNRQCGSGLQALADGMMQLQSGQAEVVVACGTENMTQLPYYLRKARDGY 135
Query: 194 --GGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEA 367
G +L DG++ LT +H G AEN A++ ITR+ D++A +S +++ A
Sbjct: 136 RMGHGELEDGLI-SILTWPEGPYHNGITAENVAQRFGITREAMDDFAWSSQQKALKAIAE 194
Query: 368 KAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNASTLND 547
F ++++ + VP + A +FA DE + EK L F K +G VTA N+S +ND
Sbjct: 195 GRFREQILALEVPDGKKATRLFATDEHPRDTPREKLATLRPAF-KADGVVTAANSSGIND 253
Query: 548 GXXXXXXXXXXXXKRLNVKPIARIVGFADGEC 643
G ++ + P RI G+A C
Sbjct: 254 GAAALVMMTRQQAEKRGLTPRMRIRGWAVAGC 285
>UniRef50_Q9YA31 Cluster: Acetyl-CoA acetyltransferase; n=1;
Aeropyrum pernix|Rep: Acetyl-CoA acetyltransferase -
Aeropyrum pernix
Length = 402
Score = 115 bits (276), Expect = 1e-24
Identities = 80/230 (34%), Positives = 115/230 (50%), Gaps = 7/230 (3%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFY---- 169
A + AGL V+ VCASGM S++ A+ + G + LAGGMESMSN PF
Sbjct: 78 AALKAGLRSDLEGFNVDMVCASGMASVVKASLLIDAGMYSLALAGGMESMSNAPFIAPPS 137
Query: 170 LKRG-ETSY-GGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYK 343
++ G Y G +++ D +V DGL D N+ MG A+ TA + R++ D A S
Sbjct: 138 IRWGVRLLYQGALEMKDAMVSDGLYDPLNQLVMGQEADETAWEYGAQREELDWIAYESNM 197
Query: 344 RSAAAYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYK-RVNFEKFTKLSTVFQKENGTVT 520
R+A A+E + +P K G V+ DE + E+ +KL VF + G T
Sbjct: 198 RAARAWER----GHMQKYTIPVKAGGAVVLDYDEGIRPDTTVERLSKLPPVFTPK-GPHT 252
Query: 521 AGNASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
AGN+S ++DG + + +KP ARIVG+ DP FP+ P
Sbjct: 253 AGNSSQISDGAVSLLVAGEEAVREMGLKPKARIVGWGYAGVDPRRFPVAP 302
>UniRef50_P73825 Cluster: Acetyl coenzyme A acetyltransferase; n=1;
Synechocystis sp. PCC 6803|Rep: Acetyl coenzyme A
acetyltransferase - Synechocystis sp. (strain PCC 6803)
Length = 409
Score = 113 bits (273), Expect = 3e-24
Identities = 74/229 (32%), Positives = 113/229 (49%), Gaps = 6/229 (2%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLK-R 178
A + A +P + V+ VC+S M S++ AA ++ G +ILAGG ESMS FYL R
Sbjct: 82 AALKAEIPDTVDGYAVDMVCSSAMMSVINAALTIRAGEGDLILAGGTESMSQTGFYLSHR 141
Query: 179 GETSYGGM-----QLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYK 343
Y + L D ++ DGLTD N MG E A + +R + DE A S +
Sbjct: 142 ARWGYKFLMGAPENLTDLLLHDGLTDSTNGEGMGEQTEKLAAEHGFSRIELDEVACLSQQ 201
Query: 344 RSAAAYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTA 523
R+A A E+ F E+ P+ + ++G V+ +++ E KL + F K+ G +TA
Sbjct: 202 RAAHATESGYFDSEIAPIEITSRKGTQVLASDEGIRSDTTVESLGKLRSAFAKD-GVLTA 260
Query: 524 GNASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
GN S + DG ++ +KP+A+I+G + P FP P
Sbjct: 261 GNCSQITDGAAALLLASGEAVEKYQLKPLAKILGGSWAAGTPSRFPELP 309
>UniRef50_Q0K0C1 Cluster: Acetyl-CoA acetyltransferase; n=11;
Proteobacteria|Rep: Acetyl-CoA acetyltransferase -
Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428 /
Stanier 337)(Cupriavidus necator (strain ATCC 17699 /
H16 / DSM 428 / Stanier337))
Length = 395
Score = 113 bits (273), Expect = 3e-24
Identities = 67/225 (29%), Positives = 105/225 (46%), Gaps = 2/225 (0%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A I AGLP S TVN+VC SG ++I AA ++ G I +AGGME+M P+ + G
Sbjct: 71 AAIGAGLPVSVPAMTVNRVCGSGAQAIATAADEVRLGYVDIAIAGGMENMDRAPYLMPSG 130
Query: 182 E--TSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAA 355
G L D ++ DGL D ++ H G E+ + +TR+ QD +A S + A
Sbjct: 131 RWGQRMGDSVLYDSMLHDGLFDAFSGEHSGWHTEDLVARYALTREAQDRWAERSQRNFAL 190
Query: 356 AYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNAS 535
A F ++ V K G + ++ + + +L F + +GT+TAGNA
Sbjct: 191 AQANGRFTGQIAGVATKGKGGTAMFEVDEANRPDTSLDTLGRLKPAF-RPDGTITAGNAP 249
Query: 536 TLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
LN G + ++P+ R+ + G +P F + P
Sbjct: 250 GLNSGAAAMIIAERALAEARGLQPLGRLAAYGVGAVEPGMFGLGP 294
>UniRef50_Q9RZA1 Cluster: Acetyl-CoA acetyltransferase; n=4;
root|Rep: Acetyl-CoA acetyltransferase - Deinococcus
radiodurans
Length = 461
Score = 110 bits (264), Expect = 3e-23
Identities = 73/234 (31%), Positives = 117/234 (50%), Gaps = 24/234 (10%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A + AGLP++ TVN++CASG+ ++ +AA+ ++ G + + GG+ESM+ P + +G
Sbjct: 114 AALLAGLPETVAGVTVNRLCASGLAAVNMAARAIRNGDGDVYVVGGVESMTRAPLSMPKG 173
Query: 182 ETSY--GGMQLVDGIV-----FDGLTDVYNKFHMGNCAENTAKKL--------QITRQDQ 316
++ G + D + + ++ MG AEN + +ITR+ Q
Sbjct: 174 SAAFANGNVTAYDTTLGWRYPNPAMEALFPLEAMGETAENIVGRSREGAYAGGEITREQQ 233
Query: 317 DEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKF------- 475
D +A+ S +R+ AA A F DE+VPV + ++G V ++ + E +
Sbjct: 234 DAFALESQRRAVAAINAGKFKDEIVPVEIKGRKGVTVFDTDEHPRMKKGAESYELATDPD 293
Query: 476 --TKLSTVFQKENGTVTAGNASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFA 631
L F+K G+VTAGNAS LNDG + L VKP+AR VG A
Sbjct: 294 TLAGLKPAFRK-GGSVTAGNASGLNDGAAALVLMSAERARALGVKPLARWVGGA 346
>UniRef50_Q82UG2 Cluster: Thiolase; n=98; Bacteria|Rep: Thiolase -
Nitrosomonas europaea
Length = 400
Score = 109 bits (262), Expect = 6e-23
Identities = 73/234 (31%), Positives = 117/234 (50%), Gaps = 11/234 (4%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A++ AGLP S T+N+ CASG++++ +AA ++ G +I+AGG ESMS VP
Sbjct: 76 ALLLAGLPVSVPGVTINRFCASGLQAVAMAADRIRLGEADVIIAGGTESMSMVPM----- 130
Query: 182 ETSYGGMQLVDGIVF-DGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAA 358
G ++ +F G V + MG AE A++ +++R++QD +A+ S+ R+ A
Sbjct: 131 ---MGNKVAMNPALFKPGSEQVAIAYGMGITAEKVAEQWKVSREEQDAFALESHHRAIRA 187
Query: 359 YEAKAFVDELVPVPVPQKR--------GAPVIFAEDEEYKR--VNFEKFTKLSTVFQKEN 508
E F DE+ P PV + R I + +E R + E +L VF +
Sbjct: 188 IEQGEFRDEISPYPVQENRPDLNTHEIQNTAIVRDTDEGPRADTSAEALARLRPVFAAQ- 246
Query: 509 GTVTAGNASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
G+VTAGN+S ++DG +R N+ PI R +G+ P + P
Sbjct: 247 GSVTAGNSSQMSDGAGAVMVVSEAALQRFNLTPIGRFIGYTVAGVPPEIMGVGP 300
>UniRef50_Q97W61 Cluster: Acetyl-CoA c-acetyltransferase; n=22;
cellular organisms|Rep: Acetyl-CoA c-acetyltransferase -
Sulfolobus solfataricus
Length = 397
Score = 106 bits (254), Expect = 6e-22
Identities = 70/215 (32%), Positives = 115/215 (53%), Gaps = 7/215 (3%)
Frame = +2
Query: 8 IFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGET 187
I AG+P +V+ VC+SGM S++ A+Q +++G II+AGG E+MS F +K +
Sbjct: 72 ISAGIPFEIDGFSVDMVCSSGMISVITASQMIKSGDADIIVAGGTENMSQAMFAIK-SDI 130
Query: 188 SYG-------GMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKR 346
+G ++L+D +++DGLTD + MG A+ AK I+R++ DE A S+ R
Sbjct: 131 RWGVKMLMNRNIELIDTMLYDGLTDPFQYKVMGQEADMVAKSHNISRKELDEVAYQSHLR 190
Query: 347 SAAAYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAG 526
+ A F E+V + K VI ++ + +K + L F ++G TAG
Sbjct: 191 AHKATVNGYFKSEIVEI----KADGKVINTDEGIRADTSLDKLSSLPPAF-TDDGLHTAG 245
Query: 527 NASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFA 631
N+S ++DG K L ++PIARI+G++
Sbjct: 246 NSSQISDGAAALVLVSEKAAKELKIEPIARILGYS 280
>UniRef50_UPI000038DFAF Cluster: hypothetical protein Faci_03001535;
n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical
protein Faci_03001535 - Ferroplasma acidarmanus fer1
Length = 391
Score = 104 bits (250), Expect = 2e-21
Identities = 68/215 (31%), Positives = 108/215 (50%)
Frame = +2
Query: 5 VIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGE 184
V+ A LP S ++++ C+S + + + A + G II++GGME M++VP + +
Sbjct: 77 VLLADLPVSVPAMSLDRACSSSLNATGIGALEIMAGKAGIIISGGMEHMTHVPLGVDN-Q 135
Query: 185 TSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYE 364
M+L+ + ++ ++MG AE AK I+R + DEY+ NS+KR+A AYE
Sbjct: 136 FIKPNMELMANPKYSKF-NMNVSYNMGLTAEKLAKLRNISRDEMDEYSYNSHKRAAKAYE 194
Query: 365 AKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNASTLN 544
E++PV V I ++ K E+ L + E+G +TA N+S+LN
Sbjct: 195 DGFMKGEIMPVTV----NGNTITSDLGIRKDTTLEQIKSLKPAY-SEDGIITAANSSSLN 249
Query: 545 DGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDP 649
DG K +KP+ARIV FA DP
Sbjct: 250 DGASMVMLMSGKKLKEYGLKPMARIVDFAAAGVDP 284
>UniRef50_Q7NUH9 Cluster: Acetyl-CoA C-acyltransferase; n=51;
Bacteria|Rep: Acetyl-CoA C-acyltransferase -
Chromobacterium violaceum
Length = 400
Score = 103 bits (248), Expect = 3e-21
Identities = 69/219 (31%), Positives = 112/219 (51%), Gaps = 10/219 (4%)
Frame = +2
Query: 5 VIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGE 184
V+ AGLP + T+N+ C+SG+ ++ +AA ++ G +++A G ESMS VP
Sbjct: 77 VLLAGLPNTVGGITINRYCSSGINAVQMAADRIRLGEADVVIAAGSESMSLVPM------ 130
Query: 185 TSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYE 364
G ++ +F + + MG AE A++ ++R+DQD +AV S++R+ AA +
Sbjct: 131 --MGNKVSLNPEIFAKDENYGIAYGMGLTAEKVAQQWGVSREDQDAFAVESHRRALAAID 188
Query: 365 AKAFVDELVPVPV----PQKRGAPVIFAE-----DEEYKR-VNFEKFTKLSTVFQKENGT 514
F +E+ P+ V P V+ + DE +R E KL TVF + G+
Sbjct: 189 GGKFKNEITPLEVTYRTPNLETGEVVVKKRVLDTDEGPRRETTLEGLAKLKTVFDAK-GS 247
Query: 515 VTAGNASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFA 631
VTAGN+S ++DG K N+ P+AR V F+
Sbjct: 248 VTAGNSSQMSDGAGAVILVSERVLKEFNLTPLARYVTFS 286
>UniRef50_A3LMS9 Cluster: Acetyl-CoA C-acyltransferase, peroxisomal;
n=3; Saccharomycetales|Rep: Acetyl-CoA
C-acyltransferase, peroxisomal - Pichia stipitis (Yeast)
Length = 404
Score = 103 bits (248), Expect = 3e-21
Identities = 67/211 (31%), Positives = 108/211 (51%), Gaps = 6/211 (2%)
Frame = +2
Query: 17 GLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSYG 196
G P T+N+ CAS +++ +A L TG +A G+ESM++ ++ RG +
Sbjct: 86 GFPVKTTVNTINRQCASSAQAVSYSAGSLITGENQFTIAAGVESMTH-DYFPHRGIPT-- 142
Query: 197 GMQLVDGIVFDGLTDVYNKFH-MGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKA 373
++ + + + N MG +EN A ITR+DQD +AV S+ ++A A E+
Sbjct: 143 --RIYEPFRQEASAEAQNVLMPMGITSENVANDFGITREDQDRFAVQSHLKAAKATESGH 200
Query: 374 FVDELVPVPV-PQKRGAPVIFAE---DEEYKR-VNFEKFTKLSTVFQKENGTVTAGNAST 538
F E++P+ G P+ A+ D+ + FEK + L VF KE+GT TAGN+S
Sbjct: 201 FAKEIIPINARTNAEGEPIAHAQVSKDDGIRAGSTFEKLSGLKPVF-KEDGTTTAGNSSQ 259
Query: 539 LNDGXXXXXXXXXXXXKRLNVKPIARIVGFA 631
++DG ++ +KPIAR +G A
Sbjct: 260 ISDGASAVILTTRANAEKYGIKPIARFLGSA 290
>UniRef50_Q4DNU4 Cluster: Putative uncharacterized protein; n=1;
Trypanosoma cruzi|Rep: Putative uncharacterized protein
- Trypanosoma cruzi
Length = 396
Score = 101 bits (243), Expect = 1e-20
Identities = 69/212 (32%), Positives = 108/212 (50%), Gaps = 6/212 (2%)
Frame = +2
Query: 17 GLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETS-- 190
G P + +++ CASG +I A+ + G + +AGG+ESMSN P YL T
Sbjct: 74 GAPITSGGTMLHENCASGGAAIHDVARRILLGEISVGMAGGVESMSNTPRYLYTCRTKNK 133
Query: 191 -YGGMQLVDGIVFDGLTD--VYNKFH-MGNCAENTAKKLQITRQDQDEYAVNSYKRSAAA 358
YG + LVDG++ + LTD V N MG E +K ++R+ QDE A S+ + A
Sbjct: 134 LYGDLTLVDGLM-EALTDCNVGNGGELMGLLTERLVEKYGVSRELQDEIAFRSHANATAT 192
Query: 359 YEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNAST 538
++ K D + PV V ++G + +DE K+++ FTK F+ E GT+T N+ST
Sbjct: 193 WK-KGMFDYVTPVDVFDRKGVRRV-EKDEGPKKLDMAHFTKQKPYFKPEGGTITVANSST 250
Query: 539 LNDGXXXXXXXXXXXXKRLNVKPIARIVGFAD 634
+NDG K L + +A + + +
Sbjct: 251 MNDGAAVVVLASEVRAKELGLPVLAELRAYGN 282
>UniRef50_Q8EN18 Cluster: Beta-ketothiolase; n=4; Bacteria|Rep:
Beta-ketothiolase - Oceanobacillus iheyensis
Length = 383
Score = 101 bits (241), Expect = 2e-20
Identities = 67/217 (30%), Positives = 110/217 (50%), Gaps = 1/217 (0%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A + AG P T+++ C S ++I AAQ + +G I++A G+ESMS VP
Sbjct: 70 AALIAGYPIEVPGTTIDRQCGSSQQAIHFAAQAILSGDMDIVVAAGIESMSRVPM----- 124
Query: 182 ETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAY 361
++ G++L LT Y + G AE AK+ I+R++ D +A+ S++++ A
Sbjct: 125 GSNQQGVKL-----SKSLTTKYEIINQGLSAERIAKQWNISREEMDVFALESHQKAIEAR 179
Query: 362 EAKAFVDELVPVPVPQKRGAPVIFAEDE-EYKRVNFEKFTKLSTVFQKENGTVTAGNAST 538
F ++L+ V + + G V DE + + +K LS+ F+K NG+VTAGNAS
Sbjct: 180 NNGYFTEQLMSVEITRADGTKVSIDSDEGPRENSSMDKLAGLSSPFEK-NGSVTAGNASQ 238
Query: 539 LNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDP 649
++DG + L +KP RI+ + DP
Sbjct: 239 ISDGAAALLIMSREKAQELGLKPRFRIIARSVIGSDP 275
>UniRef50_A0LKL0 Cluster: Acetyl-CoA acetyltransferases; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: Acetyl-CoA
acetyltransferases - Syntrophobacter fumaroxidans
(strain DSM 10017 / MPOB)
Length = 426
Score = 101 bits (241), Expect = 2e-20
Identities = 75/252 (29%), Positives = 121/252 (48%), Gaps = 29/252 (11%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLK-- 175
A++ AG P T+++ C SG+ +I A +Q G I++AGG+ESMS FY+
Sbjct: 69 ALLTAGWPVEVPGITLDRRCCSGLDAICFGAMKIQCGHASIVVAGGVESMSTAEFYIPGE 128
Query: 176 --------------------RGETSYGGMQLVDGI----VFDGLTDVYNKFH-MGNCAEN 280
G S G+ L D I V + + + + M AE
Sbjct: 129 FIKWGMEGRRDPRWGFMPRGHGSLSMWGLPLFDRIQRARVMSQPIERFGELNSMMTWAEA 188
Query: 281 TAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKR- 457
A+ I+R++ D +A+ S++R+ A ++ F +E+VPV VP+K+G + DE +R
Sbjct: 189 AARGENISREEADRWALRSHRRACEAIDSGKFREEIVPVVVPRKKGQSLAIDTDEPPRRD 248
Query: 458 VNFEKFTKLSTVFQKENGTVTAGNASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADG 637
EK ++L V+ E+G TAGN+S+ NDG L ++P+A + FA
Sbjct: 249 TALEKLSRLPVVY--EDGICTAGNSSSENDGAAAVVLMGESCALALGIQPLASLKSFAVA 306
Query: 638 ECDP-IDFPIXP 670
DP + +P P
Sbjct: 307 AADPTLTYPAVP 318
>UniRef50_A1SXV9 Cluster: Acetyl-CoA acetyltransferases; n=1;
Psychromonas ingrahamii 37|Rep: Acetyl-CoA
acetyltransferases - Psychromonas ingrahamii (strain 37)
Length = 437
Score = 100 bits (240), Expect = 3e-20
Identities = 72/240 (30%), Positives = 107/240 (44%), Gaps = 21/240 (8%)
Frame = +2
Query: 14 AGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETS- 190
AGLP TV++ CASGM+S+ L G I++AGG ESMSN+PF + T
Sbjct: 82 AGLPLEVIAHTVHRNCASGMESVTTGYDKLLAGNANILIAGGTESMSNLPFNFSKKMTQV 141
Query: 191 YGGMQLVDGI--------------------VFDGLTDVYNKFHMGNCAENTAKKLQITRQ 310
+ + I + +GLTD MG AE A++ ITR
Sbjct: 142 FENVMKAKSIGQKLSAISTLRPADLKPVISIVEGLTDPVCGLSMGQTAEVLAREFAITRA 201
Query: 311 DQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLST 490
+QD++A+ S+ ++A A EA F E+ P+ +P + V F ++ + EK KL
Sbjct: 202 EQDQFALQSHLKAAKANEAGFFTQEIHPIMLPPDY-SHVQFNDNAIRHDQSLEKLAKLKP 260
Query: 491 VFQKENGTVTAGNASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
F + GTVTA NA + DG K L P+ + ++ P + P
Sbjct: 261 FFDRVAGTVTAANACPITDGAGAVLIMLESKAKELGYSPLGYLKAYSYAGLQPERMGLGP 320
>UniRef50_A1SFE7 Cluster: Acetyl-CoA acetyltransferases; n=11;
Bacteria|Rep: Acetyl-CoA acetyltransferases -
Nocardioides sp. (strain BAA-499 / JS614)
Length = 404
Score = 100 bits (240), Expect = 3e-20
Identities = 72/230 (31%), Positives = 114/230 (49%), Gaps = 7/230 (3%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
AV+ AGLP S T+N++C S + + + ++ +++G ++L GG+ESMS P+ L +
Sbjct: 72 AVLLAGLPVSVPAVTLNRLCGSSLDAAIAGSRSIESGDAEVVLTGGVESMSRAPWVLPKP 131
Query: 182 ETSY--GGMQLVDGIVFDGLTD----VYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYK 343
E +Y G + V + L + +G E A++ +++R+ QDE+A S++
Sbjct: 132 ERAYPAGNVTAVSTTLGWRLVNERMPAEWTVSLGEANELLAERFEVSRERQDEFAARSHR 191
Query: 344 RSAAAYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYK-RVNFEKFTKLSTVFQKENGTVT 520
+ AA+ F D+LV VPV V DE + + E+ L VF+ E GT+T
Sbjct: 192 LADAAW-TSGFYDDLV-VPV-----EGVDLDRDEGIRPGSSAERLAGLRPVFRPE-GTIT 243
Query: 521 AGNASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
AGNAS LNDG + P+ARI G +P F P
Sbjct: 244 AGNASPLNDGASAVLLGSEAAAATIGRDPVARIAGRGASAVEPQWFGYAP 293
>UniRef50_Q89DN9 Cluster: Acetyl-CoA acetyltransferase; n=1;
Bradyrhizobium japonicum|Rep: Acetyl-CoA
acetyltransferase - Bradyrhizobium japonicum
Length = 390
Score = 99.5 bits (237), Expect = 6e-20
Identities = 71/233 (30%), Positives = 120/233 (51%), Gaps = 10/233 (4%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A + AGLPK+ +VN+ C+SG+++I +AA +++ I+AGG+ES+S VP G
Sbjct: 68 AALLAGLPKTTAGVSVNRFCSSGLQTIAMAANSIRSDGADCIVAGGVESIS-VP----GG 122
Query: 182 ETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAY 361
T + +D + D++ M + A+ A++ +++R+ QDE+++ S +R AAA
Sbjct: 123 GTP---KESIDPELLKVAPDIF--MAMIDTADIVAERYKLSREYQDEFSLESQRRMAAAQ 177
Query: 362 EAKAFVDELVPVPVPQK------RGAPVI--FAEDEEYKR--VNFEKFTKLSTVFQKENG 511
+A F DE+VP+ K + ++ + +E R E KL V +
Sbjct: 178 QANKFKDEIVPMKTKMKVVDKQTKAESIVDYVVDRDECNRPETTLEGLAKLEPV-KGPGK 236
Query: 512 TVTAGNASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
VTAGNAS L+DG ++ +KP+ R V +A C+P + I P
Sbjct: 237 FVTAGNASQLSDGAAAVVLMEAKDAEKRGLKPLGRFVAWATAGCEPDEMGIGP 289
>UniRef50_Q8NN21 Cluster: Acetyl-CoA acetyltransferases; n=9;
Corynebacterineae|Rep: Acetyl-CoA acetyltransferases -
Corynebacterium glutamicum (Brevibacterium flavum)
Length = 408
Score = 99.1 bits (236), Expect = 8e-20
Identities = 72/221 (32%), Positives = 109/221 (49%), Gaps = 13/221 (5%)
Frame = +2
Query: 47 VNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLK---RGETSYGGMQLVDG 217
+++ C SG+++I+ AA + +GA +I+AGG ESMS V + + R G MQL D
Sbjct: 86 LDRRCGSGLQAIVTAAAHVASGAADLIIAGGAESMSRVEYTVSGDIRWGVKGGDMQLRDR 145
Query: 218 IVFDGLTDVYNKFH-----MGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVD 382
+ + + H M AEN ++ I+R++QD+ + S +R A +A F D
Sbjct: 146 LA-EARETAGGRNHPIPGGMIETAENLRREYGISREEQDKISAASQQRWGKAADAGLFDD 204
Query: 383 ELVPVPVP-QKRG-APVIFAEDEEYK-RVNFEKFTKLSTVF--QKENGTVTAGNASTLND 547
E+VPV VP +KRG P I + DE + EK L + Q TVTAGNAS ND
Sbjct: 205 EIVPVTVPAKKRGQEPTIVSRDEHGRPGTTVEKLAALRPIMGRQDAEATVTAGNASGQND 264
Query: 548 GXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
G + ++P+ R+ G++ P I P
Sbjct: 265 GAAAVIVTTRAKAEEKGLRPVMRLAGWSVAAVPPETMGIGP 305
>UniRef50_Q0LZF8 Cluster: Acetyl-CoA C-acetyltransferase; n=3;
Bacteria|Rep: Acetyl-CoA C-acetyltransferase -
Caulobacter sp. K31
Length = 395
Score = 98.3 bits (234), Expect = 1e-19
Identities = 72/223 (32%), Positives = 105/223 (47%), Gaps = 7/223 (3%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
+++ AG P++ TV++ C S +I +AA + G +++AGG ESMS VP
Sbjct: 70 SLLGAGWPETIGAMTVDRKCGSSEAAIHIAAAQIAAGLSDLVVAGGAESMSRVPM----- 124
Query: 182 ETSYGGMQLVDGIVFDGL-TDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAA 358
G + + G F + +D Y G AE A K R D++A S++R+AAA
Sbjct: 125 ----GSNRSIHGEAFGWMVSDRYELTSQGEAAERIADKYGFDRDALDDFAAESHRRAAAA 180
Query: 359 YEAKAFVDELVPVPVPQK-----RGAPVIFAEDEEYKR-VNFEKFTKLSTVFQKENGTVT 520
+A F E V VPV G D+ +R + EK + L T F +ENG VT
Sbjct: 181 TDAGYFRAETVAVPVADLCEKDWEGPKDSLDGDQTIRRDTSREKLSMLKTSF-RENGRVT 239
Query: 521 AGNASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDP 649
AGNAS ++DG KR + P+A + A DP
Sbjct: 240 AGNASQISDGAAVVLLASEAAVKRFGLTPLALVRSVAVVGADP 282
>UniRef50_Q9RUF8 Cluster: Acetyl-CoA acetyltransferase; n=144;
cellular organisms|Rep: Acetyl-CoA acetyltransferase -
Deinococcus radiodurans
Length = 402
Score = 97.1 bits (231), Expect = 3e-19
Identities = 74/229 (32%), Positives = 109/229 (47%), Gaps = 10/229 (4%)
Frame = +2
Query: 14 AGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSY 193
AGLP + TVN+ C+SG+ +I LAA + G + +AGG+ES+S L + E +
Sbjct: 84 AGLPVTVSGVTVNRFCSSGLNTIALAANHVMAGQGDVFVAGGLESIS-----LTQNEHA- 137
Query: 194 GGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKA 373
L + + D+Y M AE A++ I+R+ QDEY S R+AAA +A
Sbjct: 138 NTFHLRGEWLLEHKPDIY--MSMLQTAEVVAERYGISRERQDEYGYQSQMRTAAAQQAGK 195
Query: 374 FVDELVPVPVPQK---RGAPVIFAED-----EEYKR--VNFEKFTKLSTVFQKENGTVTA 523
F E+VP+ K + I ++ +E R E KL VF E G +TA
Sbjct: 196 FDHEIVPMTATMKVQDKATGEISTQEVTRKLDEGNRPDTTLEGLAKLKPVF--EGGVITA 253
Query: 524 GNASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
GNAS L+DG + ++P+ GFA C+P + I P
Sbjct: 254 GNASQLSDGAAAVVVMNSDVARERGLQPLGVFKGFAVAGCEPDEMGIGP 302
>UniRef50_A3Q406 Cluster: Acetyl-CoA acetyltransferases; n=22;
Actinomycetales|Rep: Acetyl-CoA acetyltransferases -
Mycobacterium sp. (strain JLS)
Length = 396
Score = 96.3 bits (229), Expect = 6e-19
Identities = 67/174 (38%), Positives = 93/174 (53%), Gaps = 7/174 (4%)
Frame = +2
Query: 47 VNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSYGGM--QLVDG- 217
VN+ CAS + +I + A + G ILAGGMES S P KR + G D
Sbjct: 86 VNRQCASSLSAIAVGAGQIAAGMSRAILAGGMESCSTTPLLRKRKPFTTGKSPEDYQDPW 145
Query: 218 IVFDGL-TDVYNKFHMG-NCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELV 391
F T+ M A N A + I+R+ QDE+A+ S++R+ A +A +FVDE+V
Sbjct: 146 FPFSHPPTEDAPALDMSITVAHNCAVQYGISREAQDEWALRSHQRAVKAIDAGSFVDEIV 205
Query: 392 PVPVPQKRGAPVIFAEDEEYKRVN-FEKFTKLSTVFQKENG-TVTAGNASTLND 547
PV VPQ G + FAEDE +R + E L + + +G TVTAGN+S +ND
Sbjct: 206 PVEVPQADGGTITFAEDEHPRRESTIETLAGLKVLHPEIDGFTVTAGNSSGIND 259
>UniRef50_Q8IKW7 Cluster: Acetyl-CoA acetyltransferase, putative;
n=6; Plasmodium|Rep: Acetyl-CoA acetyltransferase,
putative - Plasmodium falciparum (isolate 3D7)
Length = 398
Score = 96.3 bits (229), Expect = 6e-19
Identities = 65/214 (30%), Positives = 96/214 (44%), Gaps = 9/214 (4%)
Frame = +2
Query: 47 VNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGET---SYGGMQLVDG 217
VN +C SG+ SI + ++ G ++ G ME MS P++LK T S G L D
Sbjct: 89 VNNLCCSGLDSITIGYDLIRGGKDTCVV-GSMECMSQSPYFLKNLRTEKYSLGNNILRDS 147
Query: 218 IVFDGLTDVYNKFHM--GNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELV 391
I+ DG + N + N E KK I R D DEY +NS+KR+A AY EL
Sbjct: 148 IIHDGYDFMVNNKELKTNNSMELFCKKYNIPRVDLDEYVINSFKRTANAYSENLIQQELF 207
Query: 392 PVPVPQKRGA----PVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNASTLNDGXXX 559
P+ + + + + DE YK N +K L++ +T N + DG
Sbjct: 208 PLVIQKNKNKMQVDKSVIDSDEIYKNYNIDKICNLNS-----ESIITNYNIAPFADGACA 262
Query: 560 XXXXXXXXXKRLNVKPIARIVGFADGECDPIDFP 661
K L++ PIA I+ + + P +FP
Sbjct: 263 LVLMSEQKLKELDINPIAEIITYDNASVYPDEFP 296
>UniRef50_Q2QAP2 Cluster: Acetyl-CoA acetyltransferase; n=2;
environmental samples|Rep: Acetyl-CoA acetyltransferase
- uncultured marine group II euryarchaeote HF70_59C08
Length = 406
Score = 95.9 bits (228), Expect = 8e-19
Identities = 70/213 (32%), Positives = 102/213 (47%), Gaps = 10/213 (4%)
Frame = +2
Query: 14 AGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYL------- 172
AG+P+ TV+++C SG++SI+ AAQ +Q G ++AGGME+MS P L
Sbjct: 85 AGIPQEVPMLTVSRICGSGVQSIVNAAQMIQLGEAATVVAGGMENMSQAPHVLRGMRDTF 144
Query: 173 KRGETSYGGMQL---VDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYK 343
+ G G +L ++ +F L D M ++ K+ +TR++ DE+A S+
Sbjct: 145 RLGRPPQAGTELPKDMEDYLFTNLLDGMCGSFMAQTSDEICKRKGVTREETDEFAAMSHA 204
Query: 344 RSAAAYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTA 523
R+AA+ E F E+VPV G ED E +L T F N VTA
Sbjct: 205 RTAASIENNIFEQEIVPV------GNIGHKDEDHVVLGCTPESLAELRTAF-GPNSLVTA 257
Query: 524 GNASTLNDGXXXXXXXXXXXXKRLNVKPIARIV 622
GNAS + DG + KP+ARIV
Sbjct: 258 GNASGVVDGGAAVVVKSASQAEADGDKPLARIV 290
>UniRef50_Q0LKV2 Cluster: Acetyl-CoA C-acyltransferase; n=2;
cellular organisms|Rep: Acetyl-CoA C-acyltransferase -
Herpetosiphon aurantiacus ATCC 23779
Length = 384
Score = 93.9 bits (223), Expect = 3e-18
Identities = 60/183 (32%), Positives = 94/183 (51%), Gaps = 1/183 (0%)
Frame = +2
Query: 5 VIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGE 184
V+ + LP + T+N++C S ++I AAQ + G +AGG+ESMS VP +
Sbjct: 71 VMLSNLPITVPAVTLNRMCGSAQQAIHFAAQAIAAGDVSYAIAGGVESMSRVPMF----S 126
Query: 185 TSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYE 364
G + + + Y H G AE A+K Q++R + D+++ S++R+AAA +
Sbjct: 127 DVTGNFATFN----PAINEKYQLVHQGESAELIAEKYQLSRTELDDWSFESHQRAAAATK 182
Query: 365 AKAFVDELVPVPVPQKRGAPVIFAEDEEYK-RVNFEKFTKLSTVFQKENGTVTAGNASTL 541
A F +L P+ K G P DE + + K L TVF + +G VTA NAS +
Sbjct: 183 AGWFSSQLAPIVGSDKTGNPHELIYDEGIRFEADRAKMGTLKTVF-RADGVVTAANASQI 241
Query: 542 NDG 550
+DG
Sbjct: 242 SDG 244
>UniRef50_Q2IN02 Cluster: Acetyl-CoA C-acyltransferase; n=3;
Myxococcales|Rep: Acetyl-CoA C-acyltransferase -
Anaeromyxobacter dehalogenans (strain 2CP-C)
Length = 435
Score = 93.5 bits (222), Expect = 4e-18
Identities = 69/235 (29%), Positives = 106/235 (45%), Gaps = 18/235 (7%)
Frame = +2
Query: 5 VIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFY----- 169
V+ LP+S TV + CA+ +++ A ++ G +AGG ES+S+ P +
Sbjct: 79 VLRTQLPRSVQAHTVARACATSIQAATDVADQIRLGHSDCAIAGGAESVSDAPIFASRPL 138
Query: 170 ------LKRGETSYGGMQLVDGI-------VFDGLTDVYNKFHMGNCAENTAKKLQITRQ 310
L R T +++ G+ L + MG AE A+ I+R
Sbjct: 139 AQALVELSRARTLADRARILAGLRPRDFTPTPPALKEPTTGLTMGESAEKMAQVNGISRA 198
Query: 311 DQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLST 490
QD A S++R+A A++A F +E++ VPVP R V ++ K E KL
Sbjct: 199 AQDRLAYESHRRAAEAWDAGRFDEEVMHVPVPP-RYDHVAARDNIVRKDTTVEALAKLRP 257
Query: 491 VFQKENGTVTAGNASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPID 655
VF + GT+TAGNAS L DG K L ++P+ + +A DP D
Sbjct: 258 VFDRRYGTITAGNASPLTDGAAALVLMSEERAKALGIRPLGFVKAYAYAALDPRD 312
>UniRef50_A0JU34 Cluster: Acetyl-CoA acetyltransferases; n=37;
Actinomycetales|Rep: Acetyl-CoA acetyltransferases -
Arthrobacter sp. (strain FB24)
Length = 412
Score = 93.5 bits (222), Expect = 4e-18
Identities = 71/224 (31%), Positives = 102/224 (45%), Gaps = 19/224 (8%)
Frame = +2
Query: 8 IFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGET 187
I AGL P T+N+ CAS +++I +A ++ G +A G+ES+S P + GET
Sbjct: 79 ILAGLDNVPGA-TINRFCASSLQTIRMAFHAIKAGEGDAFVAAGVESVSRYPNWTGAGET 137
Query: 188 SYGGMQ-------------------LVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQ 310
G D + + D+Y MG AEN A I+R
Sbjct: 138 DAGNHNPRFDAARRRTEARAASNTPWTDPRLGGRMPDIY--IAMGQTAENVATTYGISRA 195
Query: 311 DQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLST 490
+QDE+AV S R+ AA + F ++ P +R ++ +D V E L
Sbjct: 196 EQDEWAVLSQNRAEAARASGFFSRDITPYT---RRDGTLVDRDDSPRSGVTLEGVAGLQP 252
Query: 491 VFQKENGTVTAGNASTLNDGXXXXXXXXXXXXKRLNVKPIARIV 622
VF+ E GTVTAGNA LNDG + L ++P+ARIV
Sbjct: 253 VFRSE-GTVTAGNACPLNDGAAALVVMSDGRARELGLEPLARIV 295
>UniRef50_Q39N04 Cluster: Acetyl-CoA C-acetyltransferase; n=29;
Bacteria|Rep: Acetyl-CoA C-acetyltransferase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 423
Score = 93.1 bits (221), Expect = 6e-18
Identities = 69/230 (30%), Positives = 104/230 (45%), Gaps = 13/230 (5%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKR- 178
A + AG P T+ + C S ++I AAQ + G I++AGG+ESMS VP R
Sbjct: 99 AWLAAGFPAHVPATTIERKCGSSQQAIHFAAQAIMAGVNDIVIAGGVESMSRVPMGSARI 158
Query: 179 GETSYGG---MQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRS 349
YG + G+V G++ A+ A+K ++R+ D Y+ S++R+
Sbjct: 159 DRDPYGARFHARFPQGLVGQGVS-----------ADLVAQKWDLSREALDAYSAESHRRA 207
Query: 350 AAAYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKE-------- 505
AA A F E+VP+ VP G + ++ + E+ L+ F+
Sbjct: 208 EAARTAGQFAREIVPIDVPGDGGLRRVDTDETIRVGTSVERLASLAPSFENAELAQRFPG 267
Query: 506 -NGTVTAGNASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPI 652
VTAGNAS ++DG RL +KP ARIV F DP+
Sbjct: 268 IRWNVTAGNASQISDGAAALLVMSEQKAARLGLKPRARIVAFDVCGDDPL 317
>UniRef50_Q8SXL6 Cluster: RE07481p; n=1; Drosophila
melanogaster|Rep: RE07481p - Drosophila melanogaster
(Fruit fly)
Length = 241
Score = 93.1 bits (221), Expect = 6e-18
Identities = 51/125 (40%), Positives = 72/125 (57%), Gaps = 2/125 (1%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVP--FYLK 175
A + AGLP +N +C SG+K++ L Q +++G I++AGG ESMS P +L+
Sbjct: 69 ASLKAGLPIQVPAYGINMLCGSGLKTVALGYQAIRSGDAQIVVAGGQESMSLAPHVMHLR 128
Query: 176 RGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAA 355
+G G +VD ++ DGLTD HMG AEN A K I+R+ QD YAV S R+
Sbjct: 129 QG-VKMGPGTMVDSMIHDGLTDAMENIHMGITAENLADKYNISREAQDAYAVLSQNRAEE 187
Query: 356 AYEAK 370
A + K
Sbjct: 188 AQKKK 192
>UniRef50_A5UWB8 Cluster: Acetyl-CoA acetyltransferase; n=3;
Bacteria|Rep: Acetyl-CoA acetyltransferase - Roseiflexus
sp. RS-1
Length = 385
Score = 92.7 bits (220), Expect = 7e-18
Identities = 67/225 (29%), Positives = 108/225 (48%), Gaps = 2/225 (0%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A + AGLP+S T+++ C S +++I AAQG+ G +++A G+ESM+ VP +
Sbjct: 70 AWLAAGLPESVPATTIDRQCGSSLQAIHFAAQGVMAGVYDLVIAAGVESMTRVP--IGAS 127
Query: 182 ETSYGGMQLVDGIVFD-GLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAA 358
G L G+ GL + F AE A++ + TR+D D Y++ S++ +A A
Sbjct: 128 IMVGPGTPLSPGLATRYGLERGW--FDQARGAEWMAREWRFTREDLDRYSLRSHRLAAEA 185
Query: 359 YEAKAFVDELVPVPVPQKRGAPVIFAEDEEYK-RVNFEKFTKLSTVFQKENGTVTAGNAS 535
A F E++PV + F DE + + ++ L F + +TAGNAS
Sbjct: 186 RAAGRFTAEIIPVSLTD----GTHFEADEGIRPDTSADQLAALKPAF-PDLELITAGNAS 240
Query: 536 TLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
++DG + L ++P AR V FA DP+ P
Sbjct: 241 QISDGAAATLIASPSAAQALGLRPQARFVSFAVVGVDPVTMLTGP 285
>UniRef50_Q0EXX9 Cluster: Acetyl-CoA acyltransferase; n=2;
Proteobacteria|Rep: Acetyl-CoA acyltransferase -
Mariprofundus ferrooxydans PV-1
Length = 466
Score = 60.9 bits (141), Expect(2) = 1e-17
Identities = 40/150 (26%), Positives = 67/150 (44%)
Frame = +2
Query: 221 VFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVP 400
+ +GLTD MG AE A++ +TR +QD YA+ S++R+AA + F DE++ +
Sbjct: 202 LLEGLTDPTVGMGMGQTAELLAREFGVTRAEQDAYALMSHQRAAAGWSDGWFDDEVMHLF 261
Query: 401 VPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNASTLNDGXXXXXXXXXX 580
P + ++ + KL F + G+VTAGN+S + DG
Sbjct: 262 APPSYAD--VHRDEGIRAGQTLQALAKLKPAFDRPLGSVTAGNSSQITDGAAMLILSHRE 319
Query: 581 XXKRLNVKPIARIVGFADGECDPIDFPIXP 670
+ + + +A CDP + P
Sbjct: 320 KAEAEGWPIMGYLRDWAYTGCDPARMGLGP 349
Score = 51.6 bits (118), Expect(2) = 1e-17
Identities = 23/50 (46%), Positives = 36/50 (72%)
Frame = +2
Query: 14 AGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVP 163
AG+P+ TV++ CASGM++I AA+ +Q G ++LAGG+ESM++ P
Sbjct: 112 AGVPQQVPAHTVHRNCASGMQAITDAAEKIQLGRADVVLAGGVESMTHAP 161
>UniRef50_A0JVH9 Cluster: Acetyl-CoA acetyltransferases; n=20;
Bacteria|Rep: Acetyl-CoA acetyltransferases -
Arthrobacter sp. (strain FB24)
Length = 443
Score = 91.1 bits (216), Expect = 2e-17
Identities = 68/225 (30%), Positives = 102/225 (45%), Gaps = 2/225 (0%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A + AGLP++ V+++CA M ++ A G+ GA +++AGG+E M N P G
Sbjct: 94 AALLAGLPRTVPGFAVDRMCAGAMTAVTTTASGIAFGAYDVVIAGGVEHMGNHPM----G 149
Query: 182 ETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKL-QITRQDQDEYAVNSYKRSAAA 358
E + + + + D +MGN AEN + IT+ D YAV S + AAA
Sbjct: 150 EGADPNPRFMSERLVDPAA-----LNMGNTAENLHDRFPAITKDRTDAYAVASQDKLAAA 204
Query: 359 YEAKAFVDELVPVPVPQK-RGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNAS 535
Y +LVPV + +G V ++ + E L T F + +G VTAGNA+
Sbjct: 205 YGKGQIQPDLVPVATMKPGQGWTVNTVDEPPRPGTSLEDLASLRTPF-RPHGRVTAGNAA 263
Query: 536 TLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
LNDG L + R+V +A +P I P
Sbjct: 264 GLNDGATAALLASADAAAELGLPVKMRLVSYAFAGVEPEVMGIGP 308
>UniRef50_Q22106 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 460
Score = 90.6 bits (215), Expect = 3e-17
Identities = 68/223 (30%), Positives = 104/223 (46%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A + AGL S TVNK +SGMK+I+LAAQ +QTG Q + + GGMESMS VPF+L R
Sbjct: 169 AALGAGLDLSVAVTTVNKGWSSGMKAIILAAQQIQTGHQDLAIGGGMESMSQVPFFLARV 228
Query: 182 ETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAY 361
E S Q V+ V DG++D + D+ E +N + +
Sbjct: 229 EQSSNKYQ-VEQTVQDGISDFF---------------------DKQELCINGERTNGN-- 264
Query: 362 EAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNASTL 541
E+V V V K+G + +D+ K ++ + S++ GT++ + +
Sbjct: 265 ----IGPEVVAVNVKSKKGVEAV-KQDDITKIKKIKEGSVYSSIPIFPGGTISDKHIAAF 319
Query: 542 NDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
DG N+KP+ARI+ + D +DF + P
Sbjct: 320 TDGAAAVILASQEAVSEQNLKPLARILAYGDAATHQLDFAVAP 362
>UniRef50_Q2J8N8 Cluster: Acetyl-CoA C-acyltransferase; n=64;
Bacteria|Rep: Acetyl-CoA C-acyltransferase - Frankia sp.
(strain CcI3)
Length = 397
Score = 89.8 bits (213), Expect = 5e-17
Identities = 71/231 (30%), Positives = 104/231 (45%), Gaps = 14/231 (6%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
AV+ AG P+S T+++ C S ++ AAQG+ GA I++A G+ESMS VP G
Sbjct: 72 AVLSAGFPESVPATTIDRQCGSSQQAAHFAAQGVLAGAYDIVIAAGVESMSRVPM----G 127
Query: 182 ETSYG----GMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRS 349
T++G G L +GL H G AE + + +I R+D D ++ S++ +
Sbjct: 128 STTFGKDPNGPSL-HARYPEGLA------HQGIGAELVSARWKINREDLDIFSARSHQLA 180
Query: 350 AAAYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYK-RVNFEKFTKLSTVFQKE------- 505
AA+ A F E+VPV + G DE + E KL F E
Sbjct: 181 AASVAAGDFAGEIVPVEITLPDGTTAQHTVDETVRATTTVETLAKLKPSFYTEAYAARFP 240
Query: 506 --NGTVTAGNASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPI 652
+T GN+S L DG +L ++P AR FA DP+
Sbjct: 241 EITWNITPGNSSPLTDGASAVLIMSETRANKLGLRPRARFHTFALAGDDPL 291
>UniRef50_Q08VP3 Cluster: 3-ketoacyl-CoA thiolase; n=1; Stigmatella
aurantiaca DW4/3-1|Rep: 3-ketoacyl-CoA thiolase -
Stigmatella aurantiaca DW4/3-1
Length = 378
Score = 88.6 bits (210), Expect = 1e-16
Identities = 67/235 (28%), Positives = 106/235 (45%), Gaps = 18/235 (7%)
Frame = +2
Query: 5 VIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG- 181
VI AGLP+ TV + CA+ ++S+ AA + G +I+AGG ESMS+ P + R
Sbjct: 77 VIAAGLPRKIEAFTVARACATSIQSMTTAANAIAVGEAEVIIAGGTESMSDAPIFTSRPL 136
Query: 182 ----ETSYGGMQLVDGI-------------VFDGLTDVYNKFHMGNCAENTAKKLQITRQ 310
S L + + V + + MG AE AK+ I+R+
Sbjct: 137 AHALVASSKAKSLPEKLKPFQKLQGKDLLPVPPAIAEYSTGMTMGESAEKMAKENGISRE 196
Query: 311 DQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLST 490
+QD A S++ +A A++ F E++ V +P R V ++ + + +L
Sbjct: 197 EQDRIAYASHQNAARAWQEGRFDSEVMHVVIPP-RYEDVAAKDNIVRGDTSLDALGQLKP 255
Query: 491 VFQKENGTVTAGNASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPID 655
VF ++ G++TAGNAS L DG + L +PI + A DP D
Sbjct: 256 VFDRKYGSITAGNASPLTDGAAALLLMSEEKARALGYEPIGYLRAHAYAATDPGD 310
>UniRef50_A1IDF1 Cluster: Acetyl-CoA C-acyltransferase; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep: Acetyl-CoA
C-acyltransferase - Candidatus Desulfococcus oleovorans
Hxd3
Length = 394
Score = 88.2 bits (209), Expect = 2e-16
Identities = 73/234 (31%), Positives = 107/234 (45%), Gaps = 11/234 (4%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPF--YLK 175
AV AG P TVN+ C+SG+++I LA+ + +G + L GG+ESM+ VP L
Sbjct: 72 AVQMAGFPDQVSGATVNRFCSSGLEAIALASLRVMSGWSDVTLGGGVESMTYVPMGGNLP 131
Query: 176 RGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAA 355
R + + D Y MG AEN A + +I+R+DQD +A S +++
Sbjct: 132 RPHPEWSRER----------ADYY--VSMGITAENVANRYKISREDQDAFAYQSQMKASK 179
Query: 356 AYEAKAFVDELVPVP----VPQKRGA--PVIFAEDEE---YKRVNFEKFTKLSTVFQKEN 508
A K + E+VP P V Q G F +D + + E KL VF
Sbjct: 180 AKAEKQYT-EIVPTPATKFVKQADGTVKKETFLQDFDDGIREATTVEGLAKLRPVF-AAG 237
Query: 509 GTVTAGNASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
G+VTAGN+S DG K L +KPIA++ + C + + P
Sbjct: 238 GSVTAGNSSQTTDGAAVSVIMSENKVKELGLKPIAKLKIYTTVGCRSDEMGVGP 291
>UniRef50_Q2UTB1 Cluster: RIB40 genomic DNA, SC005; n=6;
Ascomycota|Rep: RIB40 genomic DNA, SC005 - Aspergillus
oryzae
Length = 413
Score = 88.2 bits (209), Expect = 2e-16
Identities = 70/233 (30%), Positives = 106/233 (45%), Gaps = 10/233 (4%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A I AG P + T+N+ C+SG+ +I G++ GA I + GGMESM+ Y R
Sbjct: 87 AQIHAGFPHTVPFHTINRQCSSGLAAITAIGNGIRAGALNIGVGGGMESMTRN--YGFRA 144
Query: 182 ETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAY 361
+ +L + D + MG +EN A + I+R+DQD +A S+K++ AA
Sbjct: 145 IPTVLWPELKESPSKDSRDCI---MPMGITSENVASRYGISREDQDVFAAESHKKATAAQ 201
Query: 362 EAKAFVDELVPVPV----PQKRGAP---VIFAEDEEYK-RVNFEKFTKLSTVFQKENGTV 517
A F E+VPV P+ AP + +D+ + ++ EK L F G
Sbjct: 202 NAGLFDSEIVPVKTLSFDPENPDAPPKEITATKDDGVRPNISVEKMASLKPAF-SPTGAS 260
Query: 518 TAGNASTLNDGXXXXXXXXXXXXKRLNVKPI--ARIVGFADGECDPIDFPIXP 670
TAGN+S ++DG L + R VG A C P + + P
Sbjct: 261 TAGNSSQVSDGAAAALLMRRSTATELGLTSSIKGRWVGTAVAGCAPDEMGVGP 313
>UniRef50_Q8KXD4 Cluster: Beta-ketothiolase; n=11;
Proteobacteria|Rep: Beta-ketothiolase - Azospirillum
brasilense
Length = 387
Score = 87.8 bits (208), Expect = 2e-16
Identities = 66/214 (30%), Positives = 101/214 (47%), Gaps = 2/214 (0%)
Frame = +2
Query: 14 AGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSY 193
A LP + T+N+ C S M++I AA +Q GA + L GG+ESMS VP
Sbjct: 84 AKLPLTAGATTINRYCGSSMQAIHQAAGAIQMGAGEVFLCGGIESMSRVP---------- 133
Query: 194 GGMQLVDGIVFDGLTDVYNKFH--MGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEA 367
M + + GL D Y + + MG AEN A++ +I+R DQ+ A S+ ++AAA +A
Sbjct: 134 --MMGYNPLPHPGLKDHYPEAYCSMGVTAENVARRYEISRADQEAMAAESHAKAAAAQQA 191
Query: 368 KAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNASTLND 547
+E+V + + A ++ + + E + L F + G+VTAG +S L D
Sbjct: 192 GRLAEEIVAI----QTAAGLVERDGCIRPGTSGETLSGLKPAFLAD-GSVTAGTSSPLTD 246
Query: 548 GXXXXXXXXXXXXKRLNVKPIARIVGFADGECDP 649
G K + +ARI A C P
Sbjct: 247 GASAVLVTTEAYAKANGLPILARIRSVAVAGCAP 280
>UniRef50_Q18QM7 Cluster: Acetyl-CoA acetyltransferases; n=2;
Desulfitobacterium hafniense|Rep: Acetyl-CoA
acetyltransferases - Desulfitobacterium hafniense
(strain DCB-2)
Length = 435
Score = 87.8 bits (208), Expect = 2e-16
Identities = 60/228 (26%), Positives = 114/228 (50%), Gaps = 9/228 (3%)
Frame = +2
Query: 14 AGL-PKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETS 190
AG+ P++P T ++ C S + ++ A+ ++ G +++ GG S S VPF L+ +
Sbjct: 83 AGISPETPSI-TYDQACTSALSTVKYGARSIKLGEAQMVMTGGSTSFSTVPFLLR--DIR 139
Query: 191 YGGMQLVDGIVFDGLTDVYNKFHMGNCAE--NTAKKLQITRQDQDEYAVNSYKRSAAAYE 364
+ G + +V D + + K + + N A + ++RQ+QDE A+ S+ + A+E
Sbjct: 140 WEGKKHSSFLVEDPIIPLGYKDYAPVAVDSGNVAVEYGVSRQEQDELALASHVKYGQAWE 199
Query: 365 AKAFVDELVPVPVPQ--KRG---APVIFAEDEEYK-RVNFEKFTKLSTVFQKENGTVTAG 526
F E+ P+ + + K+G + + A+DE+Y+ ++ E +L +F +N T TAG
Sbjct: 200 RGFFKGEMEPLEITKKDKKGKVLSAQLLAKDEQYRPEISMENLARLKPIF--DNPTCTAG 257
Query: 527 NASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
NA +NDG ++L + + +VG + P P+ P
Sbjct: 258 NAPGMNDGAAAQIITTREHAEQLGLPILYTLVGISAIALQPRIMPVSP 305
>UniRef50_P27796 Cluster: 3-ketoacyl-CoA thiolase, peroxisomal
precursor; n=13; Ascomycota|Rep: 3-ketoacyl-CoA
thiolase, peroxisomal precursor - Saccharomyces
cerevisiae (Baker's yeast)
Length = 417
Score = 87.4 bits (207), Expect = 3e-16
Identities = 57/210 (27%), Positives = 99/210 (47%), Gaps = 1/210 (0%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A + +G+P S +N+ C+SG+ ++ A ++ G I LA G+ESM+N
Sbjct: 106 ACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVESMTN-------N 158
Query: 182 ETSYGGMQLVDGIVFDGLTDVYN-KFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAA 358
+ + ++ + MG EN A +I+R+DQDE+A NSY+++ A
Sbjct: 159 YKNVNPLGMISSEELQKNREAKKCLIPMGITNENVAANFKISRKDQDEFAANSYQKAYKA 218
Query: 359 YEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNAST 538
F DE++P+ +P + +++ V E + + F K+ GT TAGNAS
Sbjct: 219 KNEGLFEDEILPIKLPD---GSICQSDEGPRPNVTAESLSSIRPAFIKDRGTTTAGNASQ 275
Query: 539 LNDGXXXXXXXXXXXXKRLNVKPIARIVGF 628
++DG +LN+ + R + F
Sbjct: 276 VSDGVAGVLLARRSVANQLNLPVLGRYIDF 305
>UniRef50_Q39TD0 Cluster: Thiolase; n=1; Geobacter metallireducens
GS-15|Rep: Thiolase - Geobacter metallireducens (strain
GS-15 / ATCC 53774 / DSM 7210)
Length = 409
Score = 87.0 bits (206), Expect = 4e-16
Identities = 69/216 (31%), Positives = 102/216 (47%), Gaps = 6/216 (2%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLK-- 175
A++ AGLP TV++ C S + ++ L + L + +A G E+MSN P L
Sbjct: 75 AMLHAGLPPETLSLTVDRACCSSLAAVQLGRKSLLLDEAKVCMAVGAENMSNTPVVLNGH 134
Query: 176 RGETSYGGMQLVDGIVFDGLTDVYNKFH-MGNCAENTAKKLQITRQDQDEYAVNSYKRSA 352
R T G ++VD + +Y F+ + A A + ++R+ QD +A S +
Sbjct: 135 RWGTGLGKPEMVDHL----NPIMYVGFNSLAGDAGAVALEYDVSREMQDAWAYASQMKYQ 190
Query: 353 AAYEAKAF--VDELVPVPVPQKRGAPVIFAEDEEYK-RVNFEKFTKLSTVFQKENGTVTA 523
AA A F +E+ + + QK+G PVIFAEDE K E KL V+ + TVTA
Sbjct: 191 AAKAAGKFRPGEEVAAIELSQKKGDPVIFAEDEFPKPNTTPEGLAKLPPVY--GSATVTA 248
Query: 524 GNASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFA 631
GNA L+ G L VKP+ I+ A
Sbjct: 249 GNAPGLDAGASALIITKRATADALGVKPLGVILSVA 284
>UniRef50_A6DTH4 Cluster: Acetyl-CoA acetyltransferase; n=1;
Lentisphaera araneosa HTCC2155|Rep: Acetyl-CoA
acetyltransferase - Lentisphaera araneosa HTCC2155
Length = 393
Score = 87.0 bits (206), Expect = 4e-16
Identities = 64/214 (29%), Positives = 106/214 (49%), Gaps = 8/214 (3%)
Frame = +2
Query: 14 AGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSY 193
AGL T+N+ CASG++SI +A Q + G ++ AGG ESMS + T
Sbjct: 76 AGLGNKITGVTINRFCASGLQSIAMAHQAIACGHASVLAAGGCESMSLL--------TLG 127
Query: 194 GGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKA 373
G + + + D D Y +MGN AE AK+ ++R D++++ S++ + A E
Sbjct: 128 GNNFVANPKLNDIFPDAY--LNMGNTAEAVAKQYNVSRTSMDKFSLRSHENALKAIEQGY 185
Query: 374 FVDELVPVPVP---QKRG----APVIFAEDEEYKR-VNFEKFTKLSTVFQKENGTVTAGN 529
F +E++P+ + K G F+ DE + + E KL VF + G+VTA +
Sbjct: 186 FKEEIIPLDLEVNHYKDGNLHTRKFRFSIDEGPRAGSSIESLAKLPAVF-RAGGSVTAAS 244
Query: 530 ASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFA 631
+S ++DG + N+ P A+++GFA
Sbjct: 245 SSQMSDGAAFSVLVNEQTLQERNLTPRAKLIGFA 278
>UniRef50_Q5C0R7 Cluster: SJCHGC03323 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC03323 protein - Schistosoma
japonicum (Blood fluke)
Length = 237
Score = 86.2 bits (204), Expect = 6e-16
Identities = 56/151 (37%), Positives = 80/151 (52%), Gaps = 16/151 (10%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXI---ILAGGMESMSNVPFY- 169
A I AG+P VN +C SG+KS+ L L + ILAGG ESMS P
Sbjct: 83 AAILAGIPYCVPAWCVNMMCGSGLKSVCLGFDRLSLSSMTDGGWILAGGQESMSQAPHAT 142
Query: 170 -----LKR--GETS-----YGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQD 313
L+R G+ + YG L+D I+ D L D + MG AEN AK+ I+R++
Sbjct: 143 PPRACLRRVGGQNTSELPNYGNFTLLDTIMNDALMDAFCNLPMGGTAENVAKRFGISREE 202
Query: 314 QDEYAVNSYKRSAAAYEAKAFVDELVPVPVP 406
QD +A+ S ++ A A +A F++E+ P+ VP
Sbjct: 203 QDVFALRSQEKYAFALKAGYFINEITPIKVP 233
>UniRef50_Q9HZJ3 Cluster: 3-ketoacyl-CoA thiolase; n=153;
Bacteria|Rep: 3-ketoacyl-CoA thiolase - Pseudomonas
aeruginosa
Length = 391
Score = 85.8 bits (203), Expect = 8e-16
Identities = 61/217 (28%), Positives = 96/217 (44%), Gaps = 1/217 (0%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A + +P + TV+++C S M ++ AAQ +QTG + + GG+E M +V
Sbjct: 76 ASLMTQIPHTSAAQTVSRLCGSSMSALHTAAQAIQTGNGDVFVIGGVEHMGHV------- 128
Query: 182 ETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAY 361
G M VD L MG AE K I+R+ QD++ S++ + A
Sbjct: 129 ----GMMHGVDPNPHLSLYAAKASGMMGLTAEMLGKMHGISREAQDKFGARSHQLAWKAT 184
Query: 362 EAKAFVDELVPVPVPQKRGAPVIFAEDEEYK-RVNFEKFTKLSTVFQKENGTVTAGNAST 538
+ F DE++P+ + G +F DE + E +L F + GTVTAG +S
Sbjct: 185 QEGKFKDEIIPMEGYDENGFLKVFDFDETIRPETTVETLAELKPAFNPKGGTVTAGTSSQ 244
Query: 539 LNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDP 649
+ DG + L ++P+A I A DP
Sbjct: 245 ITDGASCMIVMSAQRAQDLGIQPMAVIRSMAVAGVDP 281
>UniRef50_Q5YQT4 Cluster: Putative acyl-CoA thiolase; n=1; Nocardia
farcinica|Rep: Putative acyl-CoA thiolase - Nocardia
farcinica
Length = 430
Score = 85.4 bits (202), Expect = 1e-15
Identities = 73/234 (31%), Positives = 105/234 (44%), Gaps = 22/234 (9%)
Frame = +2
Query: 20 LPKSPXCP--TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKR----- 178
L P C TV + CASG++++ AA ++ G +++AGG +S SN L +
Sbjct: 78 LKLDPGCEGHTVTRACASGLQAVTTAAAAIERGEYDVMIAGGSDSTSNAEIKLPQKLVHA 137
Query: 179 -GETSYGGMQLVDGIVFDG----LTDVYNKFH----------MGNCAENTAKKLQITRQD 313
+ G +L D + TD+ MG AE A+ I R +
Sbjct: 138 GAPIALGKPKLKDYLSAAAQLAPFTDILPSRPRIAERTTGEVMGESAEKMARIHGIGRAE 197
Query: 314 QDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTV 493
QDE+A S+ R+AAA E+ F DE++ V P GA I + + EK +L V
Sbjct: 198 QDEFAARSHHRAAAAIESGRFDDEVLRVRTPD--GAE-ISRDGLVRADTSVEKLARLKPV 254
Query: 494 FQKENGTVTAGNASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPID 655
F E GTVTAGNAS L DG + L +P+A ++ DP D
Sbjct: 255 F-AEGGTVTAGNASPLTDGASAVLLMSEERARALGYRPLAAFRSWSYVSVDPTD 307
>UniRef50_A4TXT3 Cluster: Acetyl-CoA acetyltransferase; n=1;
Magnetospirillum gryphiswaldense|Rep: Acetyl-CoA
acetyltransferase - Magnetospirillum gryphiswaldense
Length = 240
Score = 85.4 bits (202), Expect = 1e-15
Identities = 45/118 (38%), Positives = 64/118 (54%), Gaps = 3/118 (2%)
Frame = +2
Query: 14 AGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSY 193
AG+P + T+NK+C SGMK+ M A L G +++AGGMESM+N P+ L + Y
Sbjct: 75 AGIPDAAGATTINKMCGSGMKAAMFAHDMLIAGTNRVMVAGGMESMTNAPYLLDKARGGY 134
Query: 194 --GGMQLVDGIVFDGLTDVYNKFH-MGNCAENTAKKLQITRQDQDEYAVNSYKRSAAA 358
G +++D + DGL D Y+K MG E Q TRQ Q ++ + S R A
Sbjct: 135 RMGHGRVMDHMFLDGLEDAYDKGRLMGTFPEGCGPSFQFTRQGQAQFGLRSAGRRCKA 192
>UniRef50_Q0RXS1 Cluster: Acetyl-CoA C-acetyltransferase; n=1;
Rhodococcus sp. RHA1|Rep: Acetyl-CoA C-acetyltransferase
- Rhodococcus sp. (strain RHA1)
Length = 388
Score = 85.0 bits (201), Expect = 1e-15
Identities = 65/210 (30%), Positives = 98/210 (46%), Gaps = 3/210 (1%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLK-R 178
A I G+P + T+N VC + + + +AA ++ G L GG ESMS ++ R
Sbjct: 71 AAIHGGVPTTVPGTTINDVCLASVTATGMAASMIRGGEIDTALVGGFESMSRALHGVQVR 130
Query: 179 GETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAA 358
G LVD +V DGL + MG ++ ++ ITR DQDE+A S++R+ AA
Sbjct: 131 AAAKVGHGGLVDLLVNDGLWCAVSDSGMGEISDQANREHGITRADQDEFACASHRRATAA 190
Query: 359 YEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQ--KENGTVTAGNA 532
E+ F E+ R I DE + + TKL+T+ E GT+TAGNA
Sbjct: 191 TESGRFKQEI--------RALTDILDADEGIRPGS--TVTKLATLRPAFTEGGTITAGNA 240
Query: 533 STLNDGXXXXXXXXXXXXKRLNVKPIARIV 622
S ++D L + P+ +V
Sbjct: 241 SQMSDAAAAGVLMSLGVADSLGLDPLVEVV 270
>UniRef50_Q47DJ3 Cluster: Thiolase; n=2; Bacteria|Rep: Thiolase -
Dechloromonas aromatica (strain RCB)
Length = 395
Score = 84.6 bits (200), Expect = 2e-15
Identities = 65/219 (29%), Positives = 100/219 (45%), Gaps = 2/219 (0%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A++ AGLP ++N++C S ++ AAQ + G + G+E+MS VP +L
Sbjct: 73 ALLLAGLPAEIPGVSLNRMCGSSQYAVHAAAQSILAGDAEFSVGCGVENMSRVPMFLDL- 131
Query: 182 ETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAY 361
G + D + G+T + H AE QI+R + DE+A S++R+ AA
Sbjct: 132 TLGKGDFKGFDNL-HPGITARFAIPHQVESAELIGDHWQISRAECDEFARESHRRAHAAR 190
Query: 362 EAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRV-NFEKFTKLSTVFQ-KENGTVTAGNAS 535
A E+V K G + DE + V + +K + + VF+ E G VTA NAS
Sbjct: 191 LAGVH-KEIVATAGVDKEGNAITLDYDEGVRPVIDVDKMSAMLPVFRTPETGVVTAANAS 249
Query: 536 TLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPI 652
++DG RL +KP AR DP+
Sbjct: 250 QMSDGAAAVVLGSAESAARLGLKPKARFKARVVVGSDPV 288
>UniRef50_A4BBG3 Cluster: Acetyl-CoA acetyltransferase; n=1;
Reinekea sp. MED297|Rep: Acetyl-CoA acetyltransferase -
Reinekea sp. MED297
Length = 393
Score = 84.6 bits (200), Expect = 2e-15
Identities = 59/203 (29%), Positives = 91/203 (44%), Gaps = 2/203 (0%)
Frame = +2
Query: 47 VNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVF 226
+++ C S + ++ A + GA + LAGG E MS VP + G+ +D
Sbjct: 91 IDQQCGSSLAALRFAMMTIACGANTVALAGGYEQMSRVPMGPALFKDGTLGVPTLDSAT- 149
Query: 227 DGLT-DVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPV 403
G T D+ +MG AE A ITR + D +A S++R+ + ++ DE++ +P+
Sbjct: 150 -GKTYDMTVALNMGLTAERLAAHAGITRDEMDRFACRSHERAYRSQQSGFLADEILAIPL 208
Query: 404 PQKRGAPVIFAEDEEYK-RVNFEKFTKLSTVFQKENGTVTAGNASTLNDGXXXXXXXXXX 580
++ FA D + EK LS F E G +TAGN+S L G
Sbjct: 209 DHEK----TFAHDAAIRPETTEEKLATLSPAF-SEQGDITAGNSSPLTSGASLAMLMSEQ 263
Query: 581 XXKRLNVKPIARIVGFADGECDP 649
+ P+ARIVG D P
Sbjct: 264 AMSDHGLTPMARIVGCVDRGTQP 286
>UniRef50_A0E400 Cluster: Chromosome undetermined scaffold_77, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_77,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 412
Score = 84.6 bits (200), Expect = 2e-15
Identities = 61/227 (26%), Positives = 103/227 (45%), Gaps = 4/227 (1%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A +G P + +N+ C+SG+++ + A +++G I + G+E M+ Y +
Sbjct: 91 AAFLSGFPDTTCLTAINRFCSSGIEACAVIAAKIRSGMLDIGIGAGVEQMT---MYDMQS 147
Query: 182 ETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAY 361
+ + +L+ +FD MG +EN A + +TR QD++A S +++ A
Sbjct: 148 QMN---AELLSDAIFDHPCARDCLLGMGQTSENVAAQFGVTRLQQDKFAYESQQKAYKAQ 204
Query: 362 EAKAFVDELVPVPVPQKRG---APVIFAEDEEY-KRVNFEKFTKLSTVFQKENGTVTAGN 529
+ + DE++PV K G VI ED+ K E KL F K+ G+ TAGN
Sbjct: 205 QEGLYKDEIIPVKTFIKDGDKTKEVIVTEDDGIRKETTLEGLGKLKPAFGKD-GSTTAGN 263
Query: 530 ASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
+S + DG K+L + +AR V + P I P
Sbjct: 264 SSQVTDGAAAVLLARRSVAKKLGLPILARFVDYTVAGVPPNIMGIGP 310
>UniRef50_A7AWF2 Cluster: Thiolase, N-terminal and C-terminal domain
containing protein; n=1; Babesia bovis|Rep: Thiolase,
N-terminal and C-terminal domain containing protein -
Babesia bovis
Length = 381
Score = 84.2 bits (199), Expect = 3e-15
Identities = 60/219 (27%), Positives = 100/219 (45%), Gaps = 3/219 (1%)
Frame = +2
Query: 14 AGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSY 193
AGLP + C +N +C SG+KS+ +A G+ G + G+ES S P+ L +
Sbjct: 71 AGLPNTTKCMQINHLCTSGLKSVTIATDGIALGKSQLTAVVGVESSSQSPYLLTKARE-- 128
Query: 194 GGMQLVDGIVFDGLT-DVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAK 370
GG L DG++ D LT D ++ M + K ++IT + +Y ++++AA Y
Sbjct: 129 GGYGLGDGVLVDPLTSDGFSSPCMD--PDTFLKHVKITNAELSQYVQEMFQQTAACYSDG 186
Query: 371 AFVDELVPVPVPQKRGAPV--IFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNASTLN 544
+E++PV V +K ++ + K V+ + KL +N + + TL
Sbjct: 187 IMQNEIIPVVVNRKNNHKYGGLWITPPQQK-VSEDILPKL---HNPKNLSGSIKTICTLA 242
Query: 545 DGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFP 661
DG RL + P ARI+ + + D FP
Sbjct: 243 DGAACLLLANDDFVNRLGISPYARILSYCEESVDGSQFP 281
>UniRef50_Q9AA29 Cluster: Thiolase family protein; n=42;
Bacteria|Rep: Thiolase family protein - Caulobacter
crescentus (Caulobacter vibrioides)
Length = 390
Score = 82.6 bits (195), Expect = 8e-15
Identities = 64/213 (30%), Positives = 103/213 (48%), Gaps = 7/213 (3%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYL--- 172
AV+ + LP+S +V++ C S +SI AA + +GA I++A G+ESMS VP L
Sbjct: 70 AVLASKLPESVPATSVDRQCGSSQQSIHFAAATVMSGAMDIVIAAGVESMSRVPMGLSSA 129
Query: 173 ---KRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYK 343
K G +Y ++ + + G+ +F AE AKK ++R+ D +A+ S++
Sbjct: 130 LPYKNGFGTYKSPRMEER--YPGI-----QFSQFAGAEMLAKKYDLSREQLDAFALASHQ 182
Query: 344 RSAAAYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYK-RVNFEKFTKLSTVFQKENGTVT 520
R+ AA + F E+VP+ V G+ DE + E + + E+G +T
Sbjct: 183 RAMAATKGGKFAAEIVPIKVTLPDGSVETHDADEGIRWDATMESIGGVKLL--SEDGRLT 240
Query: 521 AGNASTLNDGXXXXXXXXXXXXKRLNVKPIARI 619
A +S + DG K L V P+ARI
Sbjct: 241 AATSSQICDGAAGVMIVNERGLKALGVAPLARI 273
>UniRef50_Q2RNW4 Cluster: Acetyl-CoA C-acetyltransferase precursor;
n=1; Rhodospirillum rubrum ATCC 11170|Rep: Acetyl-CoA
C-acetyltransferase precursor - Rhodospirillum rubrum
(strain ATCC 11170 / NCIB 8255)
Length = 386
Score = 82.2 bits (194), Expect = 1e-14
Identities = 68/216 (31%), Positives = 100/216 (46%)
Frame = +2
Query: 14 AGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSY 193
AGLP + +V++ C SG+++I+ AA ++ GA +ILAGG+ES S P+ ++R +
Sbjct: 70 AGLPPAVPALSVDRQCGSGLEAILQAAWKIRAGAARVILAGGVESTSCAPWRVERPSSPT 129
Query: 194 GGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKA 373
+ V F G + M A+ A+ I R QD YA S+ R+ AA A
Sbjct: 130 DLPRFVAQAPFSG--GGHRDPSMIEGADAVAETCGIGRAAQDAYAAGSHARALAAQAAGR 187
Query: 374 FVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNASTLNDGX 553
F ELV V P + A++ + + +L + + GTVT GN+ ND
Sbjct: 188 FAGELVSVYGPPE-------ADEGPRPGLTAARLGRLKPL--RAGGTVTVGNSCATNDCA 238
Query: 554 XXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFP 661
+RL V RIV A G DP FP
Sbjct: 239 ALLMVVEAGFARRLGVTHALRIVDGAAGGGDPA-FP 273
>UniRef50_Q11I56 Cluster: Acetyl-CoA acetyltransferases; n=26;
Proteobacteria|Rep: Acetyl-CoA acetyltransferases -
Mesorhizobium sp. (strain BNC1)
Length = 462
Score = 80.2 bits (189), Expect = 4e-14
Identities = 68/245 (27%), Positives = 104/245 (42%), Gaps = 22/245 (8%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A + G+ ++ TV C SGM+SI + ++ G +ILAGG E++S+ P L R
Sbjct: 105 AALRLGMGEAMRAFTVQINCGSGMQSIDTGFRLIEGGEADLILAGGAEALSHAPLVLSRK 164
Query: 182 ETSYGGMQLVDGIVFD---------------------GLTDVYNKFHMGNCAENTAKKLQ 298
+ +D GLTD F MG AE
Sbjct: 165 AAGWFAQFATAKTAWDRAAALGAFRPDMAKPIIGLERGLTDPITDFSMGQTAEIIGHAFG 224
Query: 299 ITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKR-VNFEKF 475
+TRQ D YA+ S++R A A +A+ F+ V V ++ D+ + + EK
Sbjct: 225 VTRQAADAYALESHRRLARA-QAEGFLKGEVIASVAADG---TLYDHDDGVRPDSSIEKL 280
Query: 476 TKLSTVFQKENGTVTAGNASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPID 655
+L VF++ +G VT GN+S + DG ++ + PIARIV DP
Sbjct: 281 ARLKPVFERPHGRVTPGNSSQITDGASWVVIASEEAIEKYGLTPIARIVDSEWAALDPSV 340
Query: 656 FPIXP 670
+ P
Sbjct: 341 MGLGP 345
>UniRef50_Q9KWK4 Cluster: Putative acetyl-CoA C-acetyltransferase
vraB; n=17; Staphylococcus|Rep: Putative acetyl-CoA
C-acetyltransferase vraB - Staphylococcus aureus
Length = 379
Score = 79.8 bits (188), Expect = 5e-14
Identities = 57/184 (30%), Positives = 92/184 (50%), Gaps = 1/184 (0%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A++ AGL S T+++ C SG++S+ A + +Q GA + +AGG+ES S P+ +KR
Sbjct: 67 ALLEAGLKDSIPGVTIDRQCGSGLESVQYACRMIQAGAGKVYIAGGVESTSRAPWKIKRP 126
Query: 182 ETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAY 361
+ Y L + + M AEN AK ++R+ QDE+A S++ +A
Sbjct: 127 HSVY-ETALPEFYERASFAPEMSDPSMIQGAENVAKMYDVSRELQDEFAYRSHQLTAENV 185
Query: 362 EAKAFVDELVPVPVPQKRGAPVIFAEDEEYK-RVNFEKFTKLSTVFQKENGTVTAGNAST 538
+ E++P+ V + IF DE K + + F + V + GTVTA N+
Sbjct: 186 KNGNISQEILPITVKGE-----IFNTDESLKSHIPKDNFGRFKPVI--KGGTVTAANSCM 238
Query: 539 LNDG 550
NDG
Sbjct: 239 KNDG 242
>UniRef50_P21775-2 Cluster: Isoform 2 of P21775 ; n=4;
Euarchontoglires|Rep: Isoform 2 of P21775 - Rattus
norvegicus (Rat)
Length = 373
Score = 79.4 bits (187), Expect = 7e-14
Identities = 62/212 (29%), Positives = 105/212 (49%), Gaps = 5/212 (2%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A +G+P++ VN+ C+SG++++ A G++ G+ I +A G+ESMS RG
Sbjct: 104 AQFLSGIPETVPLSAVNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMS----LSNRG 159
Query: 182 ETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAY 361
+L++ D D MG +EN A++ I+RQ QD +A+ S +++A+A
Sbjct: 160 NPGNISSRLLES---DKARDCL--IPMGITSENVAERFGISRQKQDAFALASQQKAASAQ 214
Query: 362 EAKAFVDELVPVP--VPQKRG--APVIFAEDEEYK-RVNFEKFTKLSTVFQKENGTVTAG 526
F E+VPV V +G + ++DE + E KL F K+ G+ TAG
Sbjct: 215 SKGCFRAEIVPVTTTVLDDKGDRKTITVSQDEGVRPSTTMEGLAKLKPAF-KDGGSTTAG 273
Query: 527 NASTLNDGXXXXXXXXXXXXKRLNVKPIARIV 622
N+S ++DG + L + PI ++
Sbjct: 274 NSSQVSDGAAAVLLARRSKAEELGL-PILGVL 304
>UniRef50_Q8SVA6 Cluster: Similarity to 3-KETOACYL COA THIOLASE;
n=1; Encephalitozoon cuniculi|Rep: Similarity to
3-KETOACYL COA THIOLASE - Encephalitozoon cuniculi
Length = 391
Score = 78.6 bits (185), Expect = 1e-13
Identities = 61/222 (27%), Positives = 99/222 (44%)
Frame = +2
Query: 5 VIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGE 184
V+ AG+P +N++C SG++S+ L A+ +++G I LAGG ESM++ K
Sbjct: 74 VLRAGVPVETPVMIINRLCGSGLESVGLIAEKIRSGRIEIGLAGGFESMTSYGLP-KEYT 132
Query: 185 TSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYE 364
S GG + D +G +E K +TR + DEYAV S KR+ A +
Sbjct: 133 LSRGG-------ACEDAEDCM--LTLGEVSEMLGKTHGVTRSEADEYAVTSQKRALEATK 183
Query: 365 AKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNASTLN 544
F+ E++P+ V + DE + + L VF +++G T+ N+S L+
Sbjct: 184 KGHFLAEIIPMRVGDE-----TVERDEGIRETSLGTIESLKPVF-RQDGVCTSANSSQLS 237
Query: 545 DGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
DG L + +A + F P D + P
Sbjct: 238 DGASAVLLMKRRRADELGLPVVAEFIDFIAVGLKPRDMGLGP 279
>UniRef50_Q5P0L6 Cluster: Putative beta-ketothiolase; n=2;
Azoarcus|Rep: Putative beta-ketothiolase - Azoarcus sp.
(strain EbN1) (Aromatoleum aromaticum (strain EbN1))
Length = 421
Score = 78.2 bits (184), Expect = 2e-13
Identities = 64/235 (27%), Positives = 101/235 (42%), Gaps = 14/235 (5%)
Frame = +2
Query: 8 IFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPF--YLKRG 181
+++G+ + V ++C +G ++I+ AA + G + LA G ESMS P Y R
Sbjct: 90 LYSGVNPNVPALLVQRLCGTGFETIIAAADQITLGKAKVALAVGTESMSRNPIAAYTHRA 149
Query: 182 ETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAY 361
G + D +++ D MG+ AEN AK+ I+R + D +A S+ + AA+
Sbjct: 150 GFRMGQLDFRD-FLWEATKDTAPGASMGDTAENLAKRYGISRGEVDRFAEQSFAHACAAW 208
Query: 362 EAKAFVDELVPVPVPQ-------KRGAPV-----IFAEDEEYKRVNFEKFTKLSTVFQKE 505
E+ F E+ PV + R + + D + +F+ KL F
Sbjct: 209 ESGWFAGEVAPVVNAKWELDGYNARSLKLADRAEVCDRDGHVRPTSFDALQKLKPAF--- 265
Query: 506 NGTVTAGNASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
G T GN+S + DG + VKP+ARIV A P I P
Sbjct: 266 GGVQTGGNSSAIVDGAAAVIVAHGDWVRAHGVKPLARIVAGASVAVPPEIMGIGP 320
>UniRef50_Q2PQZ1 Cluster: Beta-ketothiolase; n=1; Rhodococcus sp.
T104|Rep: Beta-ketothiolase - Rhodococcus sp. T104
Length = 397
Score = 77.8 bits (183), Expect = 2e-13
Identities = 56/213 (26%), Positives = 98/213 (46%), Gaps = 1/213 (0%)
Frame = +2
Query: 17 GLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSYG 196
G P +++ C S ++ + A + +G ++LAGG+E M +VP TS
Sbjct: 89 GYPPEVPAVVLDRRCGSAQTAVEMGAALVGSGTHDVVLAGGVEHMGHVPI------TSPA 142
Query: 197 GMQLVDGIVF-DGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKA 373
+ + G + + L + Y+ H G AE A + I+RQ+ DE+AV S++ + A EA
Sbjct: 143 KISELYGDPWPEALRERYDFVHQGESAELIADRWGISRQEMDEFAVRSHRLATEAIEAGR 202
Query: 374 FVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNASTLNDGX 553
F E++P+ + + A + + L T F+K+ G +TAG++S ++DG
Sbjct: 203 FDTEMIPLDLAGETRA----TDQTVRPGTTLDSLAGLKTAFRKD-GRITAGSSSPISDGA 257
Query: 554 XXXXXXXXXXXKRLNVKPIARIVGFADGECDPI 652
++ ARI+ DPI
Sbjct: 258 SGVLLASREAVDAHGLRARARILDQTTVGVDPI 290
>UniRef50_A1I8F4 Cluster: Acetyl-CoA C-acyltransferase; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep: Acetyl-CoA
C-acyltransferase - Candidatus Desulfococcus oleovorans
Hxd3
Length = 391
Score = 77.0 bits (181), Expect = 4e-13
Identities = 62/221 (28%), Positives = 94/221 (42%), Gaps = 3/221 (1%)
Frame = +2
Query: 17 GLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG--ETS 190
G P+S T+ C SGM + M AA+ + TG I++A G E M VP
Sbjct: 78 GYPESVPSNTITNQCPSGMAATMHAARAIITGEADIMIAAGAEDMEKVPMAANMDFPPRL 137
Query: 191 YGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAK 370
+ L D F MG+ AE A+ +I+R+D D A+ S K++AAA +A
Sbjct: 138 FSRYNLAD-------------FPMGSTAEKVAEMYKISREDMDNMAIWSNKKAAAARDAG 184
Query: 371 AFVDELVPVPVPQKRGAPVIFAEDEEYK-RVNFEKFTKLSTVFQKENGTVTAGNASTLND 547
F +E+VP+ G + D+ + +V+ K + + F K +G VTA +S L
Sbjct: 185 KFKNEIVPIKGLDDAGNEFLVEHDQWIRDKVDPAKMASMKSPF-KPDGNVTAATSSPLTQ 243
Query: 548 GXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
G L + + G CDP + P
Sbjct: 244 GACCMLMMSRKKADALGLSYTYKYSYGVLGGCDPTIMGMAP 284
>UniRef50_A1D2F8 Cluster: 3-ketoacyl-CoA ketothiolase (Kat1),
putative; n=27; Eukaryota|Rep: 3-ketoacyl-CoA
ketothiolase (Kat1), putative - Neosartorya fischeri
(strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus
fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181))
Length = 435
Score = 77.0 bits (181), Expect = 4e-13
Identities = 62/214 (28%), Positives = 91/214 (42%), Gaps = 6/214 (2%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A + AG+P + +VN+ C+SG+K++ A +Q GA + +A G E MS L R
Sbjct: 114 AALAAGIPHTAGASSVNRFCSSGLKAVQDIANQIQLGAIDVGVAVGAELMSAGGDRLPR- 172
Query: 182 ETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAY 361
+ L + D + MG +EN ITR+ QD YA S++R+ AA
Sbjct: 173 --PFNEEVLKNQEAADCMQP------MGQTSENVGADFNITREMQDTYAAESFRRAEAAQ 224
Query: 362 EAKAFVDELVPVPVPQK-----RGAPVIFAEDEEYK-RVNFEKFTKLSTVFQKENGTVTA 523
+A F DE+VP+ K V DE + E K+ F + T
Sbjct: 225 KAGWFDDEIVPITTKVKDPKTGEVKTVTLTRDEGIRYGTTVEALNKIRPAFPQFGNRTTG 284
Query: 524 GNASTLNDGXXXXXXXXXXXXKRLNVKPIARIVG 625
GNAS + DG LN +A+ G
Sbjct: 285 GNASQVTDGAAAILLMRRSKAIELNQPILAKFCG 318
>UniRef50_A0JWS0 Cluster: Acetyl-CoA acetyltransferases; n=2;
Arthrobacter|Rep: Acetyl-CoA acetyltransferases -
Arthrobacter sp. (strain FB24)
Length = 399
Score = 75.8 bits (178), Expect = 9e-13
Identities = 55/177 (31%), Positives = 90/177 (50%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A + AGLP S TV++ C SG+ +I+LA++ + G LAGG+ES+S P L+
Sbjct: 75 AALEAGLPVSVPGVTVDRQCGSGLDAIVLASRLVAAGGNGAFLAGGVESISTAP--LRAN 132
Query: 182 ETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAY 361
++ G F L+ + MG AEN A + I+R QD +A+ S++ + AA
Sbjct: 133 RSADGSPAFFRRAQFVPLS--FGDPDMGCAAENVAAEFGISRDRQDRFALRSHRLALAAA 190
Query: 362 EAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNA 532
A + E VP+ + + + ++D ++ ++ F E GTVTAGN+
Sbjct: 191 AAGRYSGETVPL----QAASGTVESDDGPRAGMSAALISRFPPAF-AEGGTVTAGNS 242
>UniRef50_Q4Q698 Cluster: Thiolase protein-like protein; n=7;
Trypanosomatidae|Rep: Thiolase protein-like protein -
Leishmania major
Length = 440
Score = 75.8 bits (178), Expect = 9e-13
Identities = 64/216 (29%), Positives = 96/216 (44%), Gaps = 19/216 (8%)
Frame = +2
Query: 5 VIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGE 184
VI +PK + CASG+ S+ A ++ G +++AGG +S+SN L R
Sbjct: 78 VIDLNMPKKIIGNLTSMACASGLSSLSQACMLIEGGHADVVIAGGSDSVSNTEVPLPRAV 137
Query: 185 TSYGGMQLVDGIVFDGLTDV-YN--KFHMGNCA---ENTAKKL-----------QITRQD 313
T YG M V + YN K+ G A +T K + I+R+D
Sbjct: 138 T-YGLMMAQRKGVMSFFKEAGYNPLKWFPGGIALTERSTGKTMGWHGDLIAELNSISRED 196
Query: 314 QDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNF--EKFTKLS 487
Q+ A S+ +A A +A F +E+VPV + +K + +D + K L
Sbjct: 197 QEALAAASHANAARAEKAGYFKEEIVPVTIDKKGKKAEVTCDDVMQRDTEKMKAKMPSLK 256
Query: 488 TVFQKENGTVTAGNASTLNDGXXXXXXXXXXXXKRL 595
VF+KE GT+TA +STL DG K+L
Sbjct: 257 PVFRKEGGTITAATSSTLTDGGSAMLVMSEEKAKKL 292
>UniRef50_Q81Y70 Cluster: Acetyl-CoA acetyltransferase; n=11;
Bacillus|Rep: Acetyl-CoA acetyltransferase - Bacillus
anthracis
Length = 363
Score = 75.4 bits (177), Expect = 1e-12
Identities = 64/203 (31%), Positives = 91/203 (44%), Gaps = 1/203 (0%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIV 223
T+++ C +G+++I A +Q G +AGG+ES S PF R S
Sbjct: 78 TIDRQCGAGLEAIRTACHFIQGGGGKCYIAGGVESTSTSPFQ-NRARFS----------- 125
Query: 224 FDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPV 403
+ +MG AE A+ ITR+ QDEYA SYKR+ A AK ++ E +
Sbjct: 126 ----PETIGDPNMGVAAEYVAESYNITREMQDEYACLSYKRTLQAL-AKGYIHE----EI 176
Query: 404 PQKRGAPVIFAEDEEYK-RVNFEKFTKLSTVFQKENGTVTAGNASTLNDGXXXXXXXXXX 580
G DE K +N+E+ K + NGTVTAGN+ +NDG
Sbjct: 177 LSFNG-----LLDESIKPEMNYERIIKRTKPAFLHNGTVTAGNSCGVNDGACAVLVMEEG 231
Query: 581 XXKRLNVKPIARIVGFADGECDP 649
++L KP+ R V A DP
Sbjct: 232 QARKLGYKPVLRFVRSAVVGVDP 254
>UniRef50_Q128L5 Cluster: Acetyl-CoA C-acyltransferase; n=13;
Proteobacteria|Rep: Acetyl-CoA C-acyltransferase -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 416
Score = 75.4 bits (177), Expect = 1e-12
Identities = 60/222 (27%), Positives = 94/222 (42%), Gaps = 14/222 (6%)
Frame = +2
Query: 8 IFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGET 187
++AG+P ++C +G + A + +Q+GA L G ESM+ P T
Sbjct: 81 LYAGVPLEVPALMAQRICGTGFELFRQAGEHIQSGACEAALVVGAESMTRNPIAAFDHRT 140
Query: 188 SY--GGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAY 361
+ G +++ L D +M AEN AKK +TR+ DE+A S+ R+ AA
Sbjct: 141 GFKLGAPVGFKDYMWEALKDSAAGINMIQTAENLAKKYGVTREQVDEFASQSFARAVAAQ 200
Query: 362 EAKAFVDELVPVPVP------------QKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKE 505
++ E+VPV + +G A+D + E KL V+ E
Sbjct: 201 QSGFHAGEIVPVVSETFGLEGYASRSIKLQGKLTEVAQDTHARISPAEVLAKLRPVY--E 258
Query: 506 NGTVTAGNASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFA 631
G T GN++ L D K + KP+AR+V A
Sbjct: 259 GGVQTGGNSAALVDAAAAAIVASGSYAKAHDKKPLARVVAAA 300
>UniRef50_Q5UWD8 Cluster: Acetyl-coA acetyltransferase; n=6;
Halobacteriaceae|Rep: Acetyl-coA acetyltransferase -
Haloarcula marismortui (Halobacterium marismortui)
Length = 381
Score = 75.4 bits (177), Expect = 1e-12
Identities = 57/218 (26%), Positives = 103/218 (47%), Gaps = 1/218 (0%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
+++ G P++ T ++C S + +++ AA+ ++ G + G+E MS VPF
Sbjct: 74 SILAGGFPETVPGATTTRLCGSSLTTLVDAARAIEAGDGAVYPVAGVEHMSTVPF----S 129
Query: 182 ETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAY 361
+ + ++ +D ++ MG AE A+ I+R+ QDE+A+ S++R+ AA
Sbjct: 130 DWLHPAIEQR----YDP-----DRLPMGQTAETIARTHDISRKAQDEFALRSHERAVAAM 180
Query: 362 EAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQ-KENGTVTAGNAST 538
E+ F E VPV + + ++ + E+ ++L TVF+ E TVT GNAS
Sbjct: 181 ESGRFDAETVPVHTDE----TAVESDKTPRADTSVEQLSELPTVFRDDEAATVTPGNASP 236
Query: 539 LNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPI 652
L DG + + + RI + DP+
Sbjct: 237 LTDGAAGMLVTSAAYADQHGLDVLGRIETRSVAGVDPL 274
>UniRef50_Q8NCW8 Cluster: 3-oxoacyl-CoA thiolase; n=21;
Fungi/Metazoa group|Rep: 3-oxoacyl-CoA thiolase - Homo
sapiens (Human)
Length = 326
Score = 74.9 bits (176), Expect = 2e-12
Identities = 60/212 (28%), Positives = 104/212 (49%), Gaps = 5/212 (2%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A + +P++ TVN+ C+SG++++ A G++ G+ I +A G+ESMS RG
Sbjct: 6 AQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMS----LADRG 61
Query: 182 ETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAY 361
+L++ + D MG +EN A++ I+R+ QD +A+ S +++A A
Sbjct: 62 NPGNITSRLMEK---EKARDCL--IPMGITSENVAERFGISREKQDTFALASQQKAARAQ 116
Query: 362 EAKAFVDELVPV--PVPQKRGA--PVIFAEDEEYK-RVNFEKFTKLSTVFQKENGTVTAG 526
F E+VPV V +G + +DE + E KL F+K+ G+ TAG
Sbjct: 117 SKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKD-GSTTAG 175
Query: 527 NASTLNDGXXXXXXXXXXXXKRLNVKPIARIV 622
N+S ++DG + L + PI ++
Sbjct: 176 NSSQVSDGAAAILLARRSKAEELGL-PILGVL 206
>UniRef50_P09110 Cluster: 3-ketoacyl-CoA thiolase, peroxisomal
precursor; n=50; cellular organisms|Rep: 3-ketoacyl-CoA
thiolase, peroxisomal precursor - Homo sapiens (Human)
Length = 424
Score = 74.9 bits (176), Expect = 2e-12
Identities = 60/212 (28%), Positives = 104/212 (49%), Gaps = 5/212 (2%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A + +P++ TVN+ C+SG++++ A G++ G+ I +A G+ESMS RG
Sbjct: 104 AQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMS----LADRG 159
Query: 182 ETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAY 361
+L++ + D MG +EN A++ I+R+ QD +A+ S +++A A
Sbjct: 160 NPGNITSRLMEK---EKARDCL--IPMGITSENVAERFGISREKQDTFALASQQKAARAQ 214
Query: 362 EAKAFVDELVPV--PVPQKRGA--PVIFAEDEEYK-RVNFEKFTKLSTVFQKENGTVTAG 526
F E+VPV V +G + +DE + E KL F+K+ G+ TAG
Sbjct: 215 SKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKD-GSTTAG 273
Query: 527 NASTLNDGXXXXXXXXXXXXKRLNVKPIARIV 622
N+S ++DG + L + PI ++
Sbjct: 274 NSSQVSDGAAAILLARRSKAEELGL-PILGVL 304
>UniRef50_A5DXV8 Cluster: 3-ketoacyl-CoA thiolase B; n=5;
Dikarya|Rep: 3-ketoacyl-CoA thiolase B - Lodderomyces
elongisporus (Yeast) (Saccharomyces elongisporus)
Length = 411
Score = 73.7 bits (173), Expect = 4e-12
Identities = 62/226 (27%), Positives = 101/226 (44%), Gaps = 21/226 (9%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A++ AG P + +N++C+SG+ +I A ++ G + GG+ESM+
Sbjct: 81 ALMSAGFPHTSPFIAINRLCSSGLMAISQVANKIRVGEIECGIGGGVESMTK-------- 132
Query: 182 ETSYGGMQLV--DGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAA 355
YG LV D + + MG EN +K I R QD++A +SY ++
Sbjct: 133 --DYGPQALVQIDPAYAENEEFKKTQIPMGITNENVCEKFNIKRDVQDQFAASSYNKAEK 190
Query: 356 AYEAKAFVDELVPVPVPQK------------------RGAPVIFAEDEEYK-RVNFEKFT 478
A + F DE++P+ V Q+ + V +EDE + V EK
Sbjct: 191 AQKEGRFKDEILPIEVYQEDDDDDDDDENEDDDDDEPKEKKVWVSEDEGIRPGVTAEKLG 250
Query: 479 KLSTVFQKENGTVTAGNASTLNDGXXXXXXXXXXXXKRLNVKPIAR 616
K+ F KENG+ +AGN+S + DG ++ KP+A+
Sbjct: 251 KIKPAF-KENGSSSAGNSSQVTDGAALVLLMKRSFAEKNGYKPVAK 295
>UniRef50_Q05493 Cluster: 3-ketoacyl-CoA thiolase, peroxisomal
precursor; n=17; Ascomycota|Rep: 3-ketoacyl-CoA
thiolase, peroxisomal precursor - Yarrowia lipolytica
(Candida lipolytica)
Length = 414
Score = 73.3 bits (172), Expect = 5e-12
Identities = 59/213 (27%), Positives = 94/213 (44%), Gaps = 6/213 (2%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A + AG+P++ +N+ C+SG+ ++ A ++ G I + G+ESMSN Y
Sbjct: 96 ACLVAGIPETVPFVALNRQCSSGLMAVNDVANKIRAGQIDIGIGCGVESMSNQ--YGPNS 153
Query: 182 ETSYGGMQLVDGIVFDGLTDVYN-KFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAA 358
T + F + MG +EN A K ++R+ QD +A SY+++AAA
Sbjct: 154 VTPFSNK-------FQNNEEAKKCLIPMGITSENVAAKYNVSRKAQDAFAAKSYEKAAAA 206
Query: 359 YEAKAFVDELVPVPV-----PQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTA 523
A F E++P+ + +D V EK KL F E GT A
Sbjct: 207 QAAGKFDQEILPIKTTVLDDDDNEKEVTVNKDDGIRPGVTAEKLGKLKPAFSAE-GTTHA 265
Query: 524 GNASTLNDGXXXXXXXXXXXXKRLNVKPIARIV 622
GNAS ++DG ++L +A+ V
Sbjct: 266 GNASQISDGAGAVLLMRRSVAEKLGQPILAKFV 298
>UniRef50_P55084 Cluster: Trifunctional enzyme subunit beta,
mitochondrial precursor (TP-beta) [Includes:
3-ketoacyl-CoA thiolase (EC 2.3.1.16) (Acetyl-CoA
acyltransferase) (Beta-ketothiolase)]; n=49; cellular
organisms|Rep: Trifunctional enzyme subunit beta,
mitochondrial precursor (TP-beta) [Includes:
3-ketoacyl-CoA thiolase (EC 2.3.1.16) (Acetyl-CoA
acyltransferase) (Beta-ketothiolase)] - Homo sapiens
(Human)
Length = 474
Score = 70.1 bits (164), Expect = 4e-11
Identities = 62/236 (26%), Positives = 100/236 (42%), Gaps = 18/236 (7%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFY---- 169
A + AG TV C S +++ + +G +I+AGG+E MS+VP
Sbjct: 119 AALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRK 178
Query: 170 -------LKRGETSYGGMQLVDGIVFDGLTD---VYNKFH----MGNCAENTAKKLQITR 307
L + ++ + L+ F+ L ++F MG+ A+ A ++R
Sbjct: 179 MRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRLAAAFAVSR 238
Query: 308 QDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLS 487
+QDEYA+ S+ + A + + + ++VP VP K +D + + E+ KL
Sbjct: 239 LEQDEYALRSHSLAKKAQD-EGLLSDVVPFKVPGKDTV----TKDNGIRPSSLEQMAKLK 293
Query: 488 TVFQKENGTVTAGNASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDPID 655
F K GTVTA N+S L DG + KP A + F DP D
Sbjct: 294 PAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKD 349
>UniRef50_Q5WL68 Cluster: Acetyl-CoA acetyltransferase; n=1;
Bacillus clausii KSM-K16|Rep: Acetyl-CoA
acetyltransferase - Bacillus clausii (strain KSM-K16)
Length = 394
Score = 69.3 bits (162), Expect = 8e-11
Identities = 62/221 (28%), Positives = 99/221 (44%), Gaps = 5/221 (2%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
+++ +GLP TV+ C SG+++I++AA+ +Q G + LAGG+ES S P KR
Sbjct: 65 SLLESGLPVDVPGVTVDVQCGSGLEAIIVAARHIQAGDGDVYLAGGVESTSLEP---KRI 121
Query: 182 ETSYGGM-----QLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKR 346
+ G + ++ F + M AEN A++ +I R QDEY SY+R
Sbjct: 122 AANMNGNRREWHETIERARFS--PESLGDPDMAEAAENVAEQRKIGRDAQDEYTAESYRR 179
Query: 347 SAAAYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAG 526
+ AA + F DE + A DE +++ ++ ++ GTVTA
Sbjct: 180 AWAAEQQGLFRDEKI---------AAHRDLADEGIRQMPDRLLKRVPPLYN--GGTVTAA 228
Query: 527 NASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDP 649
N+ +DG R +KP+ V A DP
Sbjct: 229 NSCAKSDGAALVLLMSKQACVRYRMKPMLAFVDAARAGYDP 269
>UniRef50_Q9AG66 Cluster: Beta ketothiolase; n=5; Rhizobiaceae|Rep:
Beta ketothiolase - Rhizobium etli
Length = 235
Score = 69.3 bits (162), Expect = 8e-11
Identities = 60/219 (27%), Positives = 98/219 (44%)
Frame = +2
Query: 14 AGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSY 193
AGLP + +++ C SG+++I++AA+ +Q A LAGG+ES+S P+ ++R + +
Sbjct: 1 AGLPMAVPGVAIDRQCGSGLEAIIMAARLIQAKAGSCFLAGGVESVSTAPWRVERPKANG 60
Query: 194 GGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKA 373
+ F + MG AEN A++ I+RQ Q + + SA ++
Sbjct: 61 AVPRFYGRARFS--PETIGDPEMGVAAENVARQFGISRQRQ---GIRPSQPSARCRSGRS 115
Query: 374 FVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNASTLNDGX 553
+ V + RG PV + E + E L VF + G+VTAGNA +NDG
Sbjct: 116 GLFRPEIVEITTMRG-PVEWDECPR-PTTSPEALANLKPVFLAD-GSVTAGNACPVNDGA 172
Query: 554 XXXXXXXXXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
+ L ++ + A DP I P
Sbjct: 173 CLVLVMSRGMARNLGIEKGLAFIDSAAAGVDPNLLGIGP 211
>UniRef50_Q02X83 Cluster: Acetyl-CoA acetyltransferase; n=2;
Lactococcus lactis|Rep: Acetyl-CoA acetyltransferase -
Lactococcus lactis subsp. cremoris (strain SK11)
Length = 382
Score = 69.3 bits (162), Expect = 8e-11
Identities = 49/169 (28%), Positives = 80/169 (47%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIV 223
T++ C SG+ +++ AA +Q+G II GG+E+ S + + +
Sbjct: 85 TIDHQCGSGLTALITAANYIQSGGASIICTGGVENTS-------QSNITIDAKSQLPIKR 137
Query: 224 FDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPV 403
F + Y MG A+ TA K I+R+ QD YA+NS++++ A + K+ + E++P
Sbjct: 138 FKMAPEPYEDLDMGIIADITALKYNISRESQDLYALNSHQKANQAIKNKSLMSEVLPYLG 197
Query: 404 PQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNASTLNDG 550
I + + E KLS F EN TAGN+ +NDG
Sbjct: 198 ENSS----IIRDQTVRPHSSLEALAKLSPAF-TENCRTTAGNSCPINDG 241
>UniRef50_O28040 Cluster: 3-ketoacyl-CoA thiolase; n=12;
Archaea|Rep: 3-ketoacyl-CoA thiolase - Archaeoglobus
fulgidus
Length = 414
Score = 68.9 bits (161), Expect = 1e-10
Identities = 59/229 (25%), Positives = 96/229 (41%), Gaps = 15/229 (6%)
Frame = +2
Query: 8 IFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGET 187
+ A LP V +VC S ++ + G I++A G E M+++P +
Sbjct: 78 LLAELPVEVPAHGVERVCNSSTTAVHHGTMEIMLGYSDIVIACGFEHMTHLPMQMDLNPH 137
Query: 188 SYGGMQLVDGIVFDGLTDVYNKFHMGNCAEN---TAK-KLQITRQDQDEYAVNSYKRSAA 355
L+ D+ MG AE AK ++ T++D DE+ V S+K +A
Sbjct: 138 IGISPTLMSRTDLIQKYDLMTAMSMGLTAEKLFEVAKDEMGWTKRDLDEWGVRSHKLAAQ 197
Query: 356 AYEAKAFVD----------ELVPVPVPQKRGAPVIFAEDEEYKR-VNFEKFTKLSTVFQK 502
A + F++ E++P+ V Q G+ + D+ + E+ KL F K
Sbjct: 198 AVKEGWFLEGEGYPMKWKGEILPIEVEQADGSKKVIDVDQSIRPDTTLEQVEKLPPAF-K 256
Query: 503 ENGTVTAGNASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDP 649
G +TAGN+S LN G K ++P+A+IV DP
Sbjct: 257 PGGVITAGNSSPLNAGATALMLMSKKKMKEYGLEPMAKIVSMGWASIDP 305
>UniRef50_A4F8Z3 Cluster: Acetyl-CoA acetyltransferase; n=2;
Actinomycetales|Rep: Acetyl-CoA acetyltransferase -
Saccharopolyspora erythraea (strain NRRL 23338)
Length = 479
Score = 67.7 bits (158), Expect = 2e-10
Identities = 64/218 (29%), Positives = 93/218 (42%), Gaps = 2/218 (0%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A + AGL TV++ CASG+ +I AA ++ GA LAGG ES S P+ R
Sbjct: 172 ASLLAGLGHDVPGMTVDRQCASGLSAITTAAALIRAGAGDWYLAGGAESPSTAPWRAWRP 231
Query: 182 ETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAY 361
++ + F MG A+ A + I+RQ QD +A S+ R+ AA
Sbjct: 232 RSAAEPPRFYARAPF--APPEIGDPEMGPAADLVAAEAGISRQRQDAFAARSHARAVAAQ 289
Query: 362 EAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNF--EKFTKLSTVFQKENGTVTAGNAS 535
F E+V V G ++ R NF E+ + F + GT TA N+
Sbjct: 290 AEGRFDAEVVDVD-----GITT-----DQRPRPNFTPERLARFRPAFTAD-GTATAANSC 338
Query: 536 TLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDP 649
++DG +RL V P R+ G+ DP
Sbjct: 339 GISDGAAAVLMTTEANRRRLGV-PGLRLAGWQTSGVDP 375
>UniRef50_Q6MM13 Cluster: Acetyl-CoA acyltransferase; n=2;
Proteobacteria|Rep: Acetyl-CoA acyltransferase -
Bdellovibrio bacteriovorus
Length = 447
Score = 66.1 bits (154), Expect = 7e-10
Identities = 41/150 (27%), Positives = 69/150 (46%)
Frame = +2
Query: 221 VFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVP 400
V GLTD + +MG AE AK+ ++R+ QD++A+ S++ ++ A + +E+ PV
Sbjct: 181 VMMGLTDPFVGINMGQTAEILAKEWGLSRETQDKFALRSHQLASKAMKEGRMREEIAPVY 240
Query: 401 VPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNASTLNDGXXXXXXXXXX 580
+ + VI + E KL F K G++TAGN+ + DG
Sbjct: 241 LAPEY-KEVISEDIGPRDTQTMEALAKLKPFFDKATGSITAGNSCPITDGAAMVLMMSRE 299
Query: 581 XXKRLNVKPIARIVGFADGECDPIDFPIXP 670
+ L KP+A I + +P + P
Sbjct: 300 KAEALGYKPLATIRSYGFAGLEPERMGLGP 329
Score = 45.2 bits (102), Expect = 0.001
Identities = 20/50 (40%), Positives = 32/50 (64%)
Frame = +2
Query: 14 AGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVP 163
AG+P TV++ CAS ++SI + +++G +ILAGG E+MS +P
Sbjct: 76 AGIPLKTSAYTVHRNCASALESISNGYEKIKSGTMDVILAGGTENMSQMP 125
>UniRef50_Q565U8 Cluster: 3-oxoacyl-CoA thiolase; n=1; uncultured
bacterium|Rep: 3-oxoacyl-CoA thiolase - uncultured
bacterium
Length = 408
Score = 65.7 bits (153), Expect = 1e-09
Identities = 56/216 (25%), Positives = 93/216 (43%), Gaps = 15/216 (6%)
Frame = +2
Query: 47 VNKVCASGMKSIMLAAQGLQ----TGAQXIILAGGMESMSNVPFYLKRGETSYGGM-QLV 211
V ++CASG ++++ A Q + I+L G E+MS P ++ S + V
Sbjct: 85 VQRICASGFQTVVNAFQQIALPDAVDDTKIVLCVGAETMSRCPQIIRSPRRSGASFWEFV 144
Query: 212 DG-----IVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAF 376
+G + GL + M A+ ++ +TRQ+ D +A S+ R+ AAY + F
Sbjct: 145 EGGQVEDSMLAGLNHDLAETAMMLTADEYGARMGVTRQECDVFADVSHSRARAAYRSSHF 204
Query: 377 -----VDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNASTL 541
+ + PV G PV A DE ++ + E KL + N V+ GNAS +
Sbjct: 205 NGGDALRGIFPVDAADLSGRPVYLARDECVRQTSLEALAKLPGI--TPNRLVSPGNASEI 262
Query: 542 NDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDP 649
+DG ++L + IV + DP
Sbjct: 263 SDGAAALVVADRAKAEKLGLPARYEIVSYGVAGVDP 298
>UniRef50_Q3INC2 Cluster: Acetyl-CoA C-acyltransferase 5; n=1;
Natronomonas pharaonis DSM 2160|Rep: Acetyl-CoA
C-acyltransferase 5 - Natronomonas pharaonis (strain DSM
2160 / ATCC 35678)
Length = 382
Score = 65.7 bits (153), Expect = 1e-09
Identities = 58/212 (27%), Positives = 91/212 (42%), Gaps = 4/212 (1%)
Frame = +2
Query: 47 VNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIV- 223
+N++C SG +++ AA + +GA +++AGG+E M+ VP G + D
Sbjct: 85 LNRMCGSGQQAVNFAAGQVASGAHDVLIAGGVEHMTRVPM-------GSDGQSVTDTYFE 137
Query: 224 -FDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVP 400
FD LT G AE A+ +R+ DE A +S R A+EA + +++V V
Sbjct: 138 HFDELTT------QGEGAERIAETYDFSRRTLDELAADSQSRCGDAWEAGHYDEQVVSVD 191
Query: 401 VPQKRGAPVIFAEDEEYK-RVNFEKFTKLSTVFQKE-NGTVTAGNASTLNDGXXXXXXXX 574
+ V DE + + E + L F+ G AGNAS + DG
Sbjct: 192 T-EVGDERVELTRDEHMRPDTDAETLSSLPLSFRDPGEGVHHAGNASGIVDGASALLVTS 250
Query: 575 XXXXKRLNVKPIARIVGFADGECDPIDFPIXP 670
+ +P+ARIV DP+ P
Sbjct: 251 EAAAEEHGWEPMARIVDSHVVGVDPVTMLTGP 282
>UniRef50_A6GTF1 Cluster: Acetyl-CoA C-acyltransferase; n=1;
Limnobacter sp. MED105|Rep: Acetyl-CoA C-acyltransferase
- Limnobacter sp. MED105
Length = 431
Score = 64.5 bits (150), Expect = 2e-09
Identities = 35/131 (26%), Positives = 63/131 (48%)
Frame = +2
Query: 236 TDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKR 415
TD + MG CAE +K +++R+D D + V S++ + A ++PV VP +
Sbjct: 168 TDFTTRKTMGVCAEQMVQKFKVSREDCDAFTVRSHQLAIEALNKGYLEGTIIPVQVPGFK 227
Query: 416 GAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNASTLNDGXXXXXXXXXXXXKRL 595
I ++ K N +K + + T+F+KE G +TA +S DG +
Sbjct: 228 HP--ITLDNTPRKDSNIQKLSTMRTIFRKE-GVITAAGSSRFTDGSAALLVTSLEAANDM 284
Query: 596 NVKPIARIVGF 628
++P+A +V +
Sbjct: 285 GLQPLAEVVDY 295
>UniRef50_Q89H19 Cluster: Acyl-CoA thiolase; n=4;
Proteobacteria|Rep: Acyl-CoA thiolase - Bradyrhizobium
japonicum
Length = 410
Score = 63.7 bits (148), Expect = 4e-09
Identities = 49/161 (30%), Positives = 76/161 (47%)
Frame = +2
Query: 14 AGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSY 193
AG T+++ C SG+ S+ +AA + GA+ +++AGG E MS +RG
Sbjct: 77 AGYDVRASAVTLDRFCGSGITSVNMAASSIMAGAEDLVIAGGCEMMS---MEGRRG---- 129
Query: 194 GGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKA 373
GG ++DG L + + H G CA+ A ITR+D D + S KR+A A
Sbjct: 130 GGPMMMDGGNL-RLRARHPQSHQGVCADAIATMEGITRRDVDALGLESQKRAAHAIANGH 188
Query: 374 FVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVF 496
F L VPV ++ G+ + E+ + E + L F
Sbjct: 189 FKKSL--VPVHREDGSLALDHEEYPRPQTTMEGLSSLKPAF 227
>UniRef50_Q63YX8 Cluster: Beta-ketoadipyl CoA thiolase; n=96;
cellular organisms|Rep: Beta-ketoadipyl CoA thiolase -
Burkholderia pseudomallei (Pseudomonas pseudomallei)
Length = 401
Score = 62.9 bits (146), Expect = 7e-09
Identities = 43/132 (32%), Positives = 67/132 (50%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
AV+ AG ++ +N+ CASG+++ +AA + +G + + GG+ESMS VP
Sbjct: 71 AVLAAGYAETTAGVQINRFCASGLEACNMAAAQVMSGQSEMAIGGGVESMSRVPM----- 125
Query: 182 ETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAY 361
S GG VD + + + G A+ A K +R D D YA S++R+ AA
Sbjct: 126 -GSSGGAWPVDPAI--AIPSYF--VPQGVSADTIATKWGYSRADVDAYAAESHRRAHAAA 180
Query: 362 EAKAFVDELVPV 397
+A F +VPV
Sbjct: 181 QAGWFARSIVPV 192
>UniRef50_Q9KT59 Cluster: 3-ketoacyl-CoA thiolase; n=113;
Proteobacteria|Rep: 3-ketoacyl-CoA thiolase - Vibrio
cholerae
Length = 435
Score = 61.7 bits (143), Expect = 2e-08
Identities = 56/228 (24%), Positives = 99/228 (43%), Gaps = 19/228 (8%)
Frame = +2
Query: 5 VIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVP------- 163
V+ G+ + +V + CA+ ++ + A+ + G+ I +AGG +S S +P
Sbjct: 80 VLGTGMSINTDAYSVTRACATSFQAAVNVAESIMAGSIDIGIAGGADSSSVLPIGVSKKL 139
Query: 164 ----FYLKRGETSYGGMQLVDGIVFDGLTDV------YNK-FHMGNCAENTAKKLQITRQ 310
L + +T ++L+ + F L V Y+ MG AE AK I+R
Sbjct: 140 AASLLALSKTKTVGQKLKLLSNLSFKDLMPVPPAVAEYSTGLSMGQTAEQMAKSYAISRA 199
Query: 311 DQDEYAVNSYKRSAAAYEAKAFVDELVPV-PVPQKRGAPVIFAEDEEYKRVNFEKFTKLS 487
+QD A S+ +A A+ DE++ P P K+ + ++ E + KL
Sbjct: 200 EQDALAHRSHTLAAQAWAEGKIRDEVMTAFPEPYKKWLDM---DNNIRMDSKLESYAKLR 256
Query: 488 TVFQKENGTVTAGNASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFA 631
F ++ G+VTA N++ L DG K L ++ + I +A
Sbjct: 257 PAFDRQYGSVTAANSTPLTDGAAAIMLMREGKAKELGLEIMGYIRSYA 304
>UniRef50_A1SKA8 Cluster: Acetyl-CoA acetyltransferases; n=24;
Actinomycetales|Rep: Acetyl-CoA acetyltransferases -
Nocardioides sp. (strain BAA-499 / JS614)
Length = 388
Score = 60.9 bits (141), Expect = 3e-08
Identities = 62/231 (26%), Positives = 97/231 (41%), Gaps = 10/231 (4%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A + AGL + ++ C SG +S L + G + +A G+E+MS +P G
Sbjct: 70 AWLHAGLAQHTGATAIDAQCGSGQQSAHLVHDMVAAGTIEVGVACGVEAMSRIPL----G 125
Query: 182 ETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAY 361
G L D D D+ N+F A+ A+ ITR D D + + S +++ A
Sbjct: 126 ANVPPG--LGDPRPDDWTIDMPNQF---EAADRIARNRGITRADLDAFGLASQQKARVAV 180
Query: 362 EAKAFVDELVP---VPVPQKRGAPV----IFAEDEEYKRVNFEKFTKLSTVFQKENGTVT 520
+ F E+ P PV + G+P + D+ + E L +V +G T
Sbjct: 181 DEGRFKREIAPYDAAPVLDEGGSPTGETRLVDTDQGLRDTTLEGLAGLRSVL--PDGLHT 238
Query: 521 AGNASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDP---IDFPI 664
AG +S ++DG + L + P ARIV DP +D PI
Sbjct: 239 AGTSSQISDGASAVLIMDSDRARALGLTPRARIVTHCLVGSDPYYHLDGPI 289
>UniRef50_Q1GSM2 Cluster: Acetyl-CoA C-acyltransferase; n=20;
Proteobacteria|Rep: Acetyl-CoA C-acyltransferase -
Sphingopyxis alaskensis (Sphingomonas alaskensis)
Length = 416
Score = 59.7 bits (138), Expect = 6e-08
Identities = 62/238 (26%), Positives = 96/238 (40%), Gaps = 22/238 (9%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A + AG T+++ C G+ S+ LAA + +G + ++AGG E MS L
Sbjct: 73 AALSAGYDIKASGTTLDRFCGGGITSVNLAAATVMSGMEDCVVAGGTEMMSYTA-QLAAE 131
Query: 182 ETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAY 361
E + G L G L +++ + H G C + A I R D A+ S +R+ A
Sbjct: 132 EANAGIKPLGMGAGHAALDELHPQSHQGVCGDAIAAIEGIDRAAVDALALVSQRRADRAI 191
Query: 362 EAKAFVDELVPVPVP--------QKRGAPVIFAEDEEYKRVNFEKFTKL----STVFQKE 505
+ F LVPV P ++ P AE + +F+ F+K+
Sbjct: 192 KEGRFAKSLVPVLNPDGSIALDHEEFPRPETTAEGLAALKPSFDAIADFDLGGGVTFRKQ 251
Query: 506 ----------NGTVTAGNASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDP 649
G AGN+S + DG + +KP ARIV +A+ DP
Sbjct: 252 IQRRYPGLEFRGVHHAGNSSGVVDGAAALLVTSKAYADKHGLKPRARIVAYANIGDDP 309
>UniRef50_A6G214 Cluster: Putative uncharacterized protein; n=1;
Plesiocystis pacifica SIR-1|Rep: Putative
uncharacterized protein - Plesiocystis pacifica SIR-1
Length = 394
Score = 59.7 bits (138), Expect = 6e-08
Identities = 49/169 (28%), Positives = 72/169 (42%), Gaps = 1/169 (0%)
Frame = +2
Query: 47 VNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVF 226
+++ CA+G ++ A +Q G L + SN P + GG + V+
Sbjct: 87 ISQACATGAAALAHAGGKVQCGDNEATLVVLADKTSNGPHLVYPNPMGPGGKPDSEDWVW 146
Query: 227 DGLT-DVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPV 403
D + D + K M AEN AK+ I+R++QD V Y++ A +AK +VPV V
Sbjct: 147 DSFSRDPWAKGSMLQTAENVAKEAGISREEQDALTVTRYEQYVAGRDAKFHERYMVPVEV 206
Query: 404 PQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNASTLNDG 550
R DE E KL E GTVT G+ + DG
Sbjct: 207 KPGRKVIATVDFDEGVFATTAEGLAKLRPAMGPE-GTVTFGSQTHPADG 254
>UniRef50_A1FU75 Cluster: Acetyl-CoA acetyltransferases; n=5;
Xanthomonadaceae|Rep: Acetyl-CoA acetyltransferases -
Stenotrophomonas maltophilia R551-3
Length = 525
Score = 58.8 bits (136), Expect = 1e-07
Identities = 60/206 (29%), Positives = 98/206 (47%), Gaps = 23/206 (11%)
Frame = +2
Query: 2 AVIFAGLPKSPXCP--TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPF-YL 172
A + +GL SP P T+ + C + + SI+ A + G + GG ++ S+VP Y
Sbjct: 171 ATLSSGL--SPLTPGITLQRACGTSLDSIITVANKIALGQIESGIGGGSDTTSDVPIVYG 228
Query: 173 K----------RGETSYGGMQ-LVDGIVFD-------GLTDVYNKFHMGNCAENTAKKLQ 298
K R +++ ++ L G F G+ + MG+ E+ AK+
Sbjct: 229 KKLRARLLAANRAKSTGDKIRALTAGFKFSELKPEFPGVAEPRTGKSMGDHCEDMAKEWN 288
Query: 299 ITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFT 478
I+R QDE+AV+S+K+ AAAYE F D + P ++ ++ A+ + EK
Sbjct: 289 ISRDSQDEWAVSSHKKLAAAYERGFFSDLIAPFRGVERDN--ILRAD------TSLEKLA 340
Query: 479 KLSTVFQKEN--GTVTAGNASTLNDG 550
L F K + GT+TA N++ L DG
Sbjct: 341 TLKPAFDKVSGRGTLTAANSTPLTDG 366
>UniRef50_Q9F8Q0 Cluster: 3-ketoacyl-CoA thiolase; n=1;
Carboxydothermus hydrogenoformans|Rep: 3-ketoacyl-CoA
thiolase - Carboxydothermus hydrogenoformans
Length = 154
Score = 58.0 bits (134), Expect = 2e-07
Identities = 37/107 (34%), Positives = 56/107 (52%), Gaps = 1/107 (0%)
Frame = +2
Query: 233 LTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQK 412
LTD +K MG AEN + I+R++QDE A S++ + A + F +E+VPV V K
Sbjct: 10 LTDPLHKILMGVTAENLPRTYNISREEQDEIAYRSHQLAVEAIDNGWFTEEIVPVEVNNK 69
Query: 413 RGAPVIFAEDEEYKRVNFEKFTKLSTVF-QKENGTVTAGNASTLNDG 550
+ ++ ++ K T S+ F + G AGN+S LNDG
Sbjct: 70 KEKVLVTTDEXPAPGYFLRKITGSSSHFCHRRXG--YAGNSSGLNDG 114
>UniRef50_Q1GWY7 Cluster: Acetyl-CoA C-acyltransferase; n=4;
Bacteria|Rep: Acetyl-CoA C-acyltransferase -
Sphingopyxis alaskensis (Sphingomonas alaskensis)
Length = 421
Score = 58.0 bits (134), Expect = 2e-07
Identities = 44/137 (32%), Positives = 72/137 (52%), Gaps = 4/137 (2%)
Frame = +2
Query: 260 MGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVIFAE 439
MG+ E+TAK +I+R+ QD++A+ S++RS A +E + F D+L + +P+ A
Sbjct: 170 MGDHMEDTAKAWRISREAQDDWALKSHQRSVAGWE-RGFFDDLA-ISLPE-------LAR 220
Query: 440 DEEYKR-VNFEKFTKLSTVFQKEN--GTVTAGNASTLNDGXXXXXXXXXXXXKRLNV-KP 607
D + + E+ L VF +++ GT+TAGN+S + DG RL P
Sbjct: 221 DANPRADTSPERLAALKPVFDRDSGRGTLTAGNSSPITDGAAGCWVANEAGVARLPAGTP 280
Query: 608 IARIVGFADGECDPIDF 658
AR++ D E +DF
Sbjct: 281 YARLI---DYEVSAVDF 294
>UniRef50_Q96CA6 Cluster: ACAA1 protein; n=16; Tetrapoda|Rep: ACAA1
protein - Homo sapiens (Human)
Length = 331
Score = 43.6 bits (98), Expect(2) = 2e-07
Identities = 30/93 (32%), Positives = 48/93 (51%), Gaps = 5/93 (5%)
Frame = +2
Query: 263 GNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPV--PVPQKRGA--PVI 430
G +EN A++ I+R+ QD +A+ S +++A A F E+VPV V +G +
Sbjct: 149 GITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSIT 208
Query: 431 FAEDEEYK-RVNFEKFTKLSTVFQKENGTVTAG 526
+DE + E KL F+K+ G+ TAG
Sbjct: 209 VTQDEGIRPSTTMEGLAKLKPAFKKD-GSTTAG 240
Score = 33.9 bits (74), Expect(2) = 2e-07
Identities = 15/49 (30%), Positives = 30/49 (61%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMES 148
A + +P++ TVN+ C+SG++++ A G++ G+ I +A G+ S
Sbjct: 104 AQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGITS 152
>UniRef50_Q6ACV5 Cluster: Acetyl-coA acyltransferase; n=2;
Actinomycetales|Rep: Acetyl-coA acyltransferase -
Leifsonia xyli subsp. xyli
Length = 371
Score = 57.6 bits (133), Expect = 3e-07
Identities = 43/132 (32%), Positives = 61/132 (46%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A + AG + TV++ C SG+ +++ A ++ G + LAGG ES S P G
Sbjct: 70 AALAAGFGAAVPGGTVDRQCGSGLAAVLDAVSAIRAGDGRVRLAGGAESASTAPVRASGG 129
Query: 182 ETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAY 361
Y G D M AE+ A+ I+R+ QD YA S+ R+ AA
Sbjct: 130 -VPYDRAPFAPA----GFPDP----DMPRAAEDLAQADGISRERQDAYAARSHARARAAR 180
Query: 362 EAKAFVDELVPV 397
EA F ELVP+
Sbjct: 181 EAGRFAGELVPL 192
>UniRef50_Q7QZB1 Cluster: GLP_567_7442_8677; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_567_7442_8677 - Giardia lamblia ATCC
50803
Length = 411
Score = 57.2 bits (132), Expect = 3e-07
Identities = 61/220 (27%), Positives = 91/220 (41%), Gaps = 25/220 (11%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIV 223
++N VC SG+++++ A + + G LA GMESMS R + + +
Sbjct: 90 SINVVCNSGIEAVIEACRRISVGEGLAYLAVGMESMS-------RAHMVHSNIATDVATI 142
Query: 224 FDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKR------------------- 346
DGL D + MG+ AE K TRQ + AV S +
Sbjct: 143 HDGLLDAETQRSMGDIAEEYYSKQHYTRQQLEAVAVASCEAALARAKPELVHIELDPASG 202
Query: 347 --SAAAYEAK---AFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENG 511
SA Y A+ A V L V +P PV F EDE+ R N K L + F ++ G
Sbjct: 203 TVSAVTYTARGDSASVHSLKLVFLP-PAAVPVSFCEDEQLIRYNRTKLPSLRSCF-RDAG 260
Query: 512 TVTAGNASTLNDGXXXXXXXXXXXXKRL-NVKPIARIVGF 628
+T+G S ++DG L +P A ++G+
Sbjct: 261 LLTSGTTSAMSDGAVAIALVAPTYEGSLAPCEPQAEVLGY 300
>UniRef50_Q0FF19 Cluster: Putative acetyl-CoA c-acetyltransferase;
n=1; alpha proteobacterium HTCC2255|Rep: Putative
acetyl-CoA c-acetyltransferase - alpha proteobacterium
HTCC2255
Length = 369
Score = 56.8 bits (131), Expect = 4e-07
Identities = 36/113 (31%), Positives = 61/113 (53%)
Frame = +2
Query: 14 AGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSY 193
AGLP+ T+++ C G+ +I LAAQ + +G+ II+AGG ES S P ++ +
Sbjct: 72 AGLPEHIGGFTIDRQCTGGLDAIWLAAQMVMSGSHNIIIAGGSESASCRPIRMRINHNT- 130
Query: 194 GGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSA 352
G D +F GL D M + A I+++ Q+ +A+NS+K+++
Sbjct: 131 GEKIAYDRPIFTGLKD--RDPDMIDSVAEIAVSSGISKEAQEAWAINSHKKAS 181
>UniRef50_A6GHQ8 Cluster: Acetyl-CoA acetyltransferase; n=1;
Plesiocystis pacifica SIR-1|Rep: Acetyl-CoA
acetyltransferase - Plesiocystis pacifica SIR-1
Length = 415
Score = 56.4 bits (130), Expect = 6e-07
Identities = 50/153 (32%), Positives = 74/153 (48%), Gaps = 2/153 (1%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A ++AG P++ T+ + CASG+ +I AA + G +I+AGG+ESMS VP R
Sbjct: 74 AALWAGWPEAVPGLTLTRFCASGLDAIGTAAARVIAGFDGLIVAGGVESMSRVPMLADR- 132
Query: 182 ETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAY 361
G +D V + V HM A+ A R+ D +A+ S+ R+ AA+
Sbjct: 133 -----GAWWMDPEVAERTRYV----HMALSADLIASLDGHGREALDAWALRSHVRARAAW 183
Query: 362 EAKAFVDELVPVPVPQKRGA--PVIFAEDEEYK 454
F +VPV RGA V+ +DE K
Sbjct: 184 AGGHFARSIVPV-----RGADGEVLLGQDERVK 211
>UniRef50_Q1AV81 Cluster: Thiolase; n=3; Actinobacteria (class)|Rep:
Thiolase - Rubrobacter xylanophilus (strain DSM 9941 /
NBRC 16129)
Length = 394
Score = 56.0 bits (129), Expect = 8e-07
Identities = 47/173 (27%), Positives = 77/173 (44%), Gaps = 3/173 (1%)
Frame = +2
Query: 41 PTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSYGGMQLVDGI 220
P V++ CA+ + + AA ++ A + SN P L + GG ++
Sbjct: 85 PMVSQACATSVACLAAAAASAAPDPTLVVAA---DRTSNGPTLLYPNPSGMGGAPEIEHW 141
Query: 221 VFDGLT-DVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAY-EAKAFVDE-LV 391
V D D + M AE A + ITR++ DE + Y++ A + +AF +V
Sbjct: 142 VLDAFARDPWAGESMVATAEAVAAEEGITREELDEVTLLRYEQYRDALADGRAFQRRYMV 201
Query: 392 PVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNASTLNDG 550
PV VP+ RG P++ ED + E +L + E G +T G+ + DG
Sbjct: 202 PVEVPRPRGEPLLLEEDHGVHPTSEEALRRLRPL--SEGGVITYGSQTHPADG 252
>UniRef50_A0NXK3 Cluster: Acetyl-CoA C-acetyltransferase; n=2;
Alphaproteobacteria|Rep: Acetyl-CoA C-acetyltransferase
- Stappia aggregata IAM 12614
Length = 395
Score = 56.0 bits (129), Expect = 8e-07
Identities = 35/119 (29%), Positives = 59/119 (49%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A + AGL ++ T++ C SG+ +I++ A+ ++ GA I+LAGG ES S P + R
Sbjct: 70 AALRAGLSQTVPALTIDTQCCSGLDAILMGARMIEAGAAEIVLAGGTESFSRSPIRMTRP 129
Query: 182 ETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAA 358
D F D ++ + A A + T++ Q YAV S+ ++A+A
Sbjct: 130 ADRAEPSVAYDRPAF--APDSFDDPDLAEAAAKLAAETGTTKEAQAAYAVASHHKAASA 186
>UniRef50_A0Z3Q6 Cluster: Acetyl-CoA acetyltransferase; n=1; marine
gamma proteobacterium HTCC2080|Rep: Acetyl-CoA
acetyltransferase - marine gamma proteobacterium
HTCC2080
Length = 415
Score = 54.0 bits (124), Expect = 3e-06
Identities = 37/137 (27%), Positives = 65/137 (47%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
+ ++AG P T+N+ C+SG+ +I +AA + G + + +AGG+E MS VP +
Sbjct: 87 SALYAGWPSHVSGLTINRFCSSGLDAINIAALKVNAGQEEVAVAGGIEMMSRVPMMSDQA 146
Query: 182 ETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAY 361
+ + MG+ A+ A +R D DE A+ S +R+A A
Sbjct: 147 AIFKDPEVALSARI----------LLMGSGADLIASLYGASRHDVDEVALMSQQRAALAR 196
Query: 362 EAKAFVDELVPVPVPQK 412
++ F ++P+ P K
Sbjct: 197 DS-GFFTSIIPIDNPVK 212
>UniRef50_Q8F7W4 Cluster: Acetyl-CoA acetyltransferase; n=4;
Leptospira|Rep: Acetyl-CoA acetyltransferase -
Leptospira interrogans
Length = 441
Score = 52.8 bits (121), Expect = 7e-06
Identities = 64/243 (26%), Positives = 104/243 (42%), Gaps = 39/243 (16%)
Frame = +2
Query: 17 GLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLK--RGETS 190
G+ C TV C SGM+++ AA+ + G + LA G ES +++PF +K R
Sbjct: 75 GMRDEIACITVANNCVSGMEAVAEAARRIVLGEGEVFLAIGEESQTSMPFVVKNARLNKK 134
Query: 191 YGGM---------QLVDGI-----VFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYA 328
G + L +G+ + DGL D + M AE A+ ++R+ QD+ A
Sbjct: 135 AGSLDKLKKLLPDNLPEGVELRDTLEDGLGDGETSYGMQVTAEIVAQNYGLSREIQDKLA 194
Query: 329 VNSYKRSAAAYEAKAFVDELVP---------------------VPVPQKRGAPVIFAEDE 445
S+KR+ A +A + ++P V P + G ++ ++
Sbjct: 195 FESFKRALEASKAGKYSPYIIPMKDDEGNELTIDEAVGLREGLVENPTRMGRAMLMFDNP 254
Query: 446 EYKRVNFEKF-TKLSTVFQKENG-TVTAGNASTLNDGXXXXXXXXXXXXKRLNVKPIARI 619
K FE+F TK S +K +G TV+ NAS +DG K L + A +
Sbjct: 255 GMK---FEEFKTKYSKDLKKSHGPTVSIFNASPRSDGAAGVIVTTVEKAKELGLTIEAVV 311
Query: 620 VGF 628
G+
Sbjct: 312 SGW 314
>UniRef50_Q184F9 Cluster: Putative thiolase; n=2; Clostridium
difficile|Rep: Putative thiolase - Clostridium difficile
(strain 630)
Length = 378
Score = 52.8 bits (121), Expect = 7e-06
Identities = 50/203 (24%), Positives = 83/203 (40%)
Frame = +2
Query: 14 AGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSY 193
AG+ TV+ CAS M SI +A +++G +I+AGG ES S P
Sbjct: 69 AGVSNEVPAFTVDMQCASAMMSIDIAFSKVKSGQCDLIIAGGFESSSLQPMRTYHKNDKR 128
Query: 194 GGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKA 373
+ V D ++ M AE A+ QI + D D + S+KR+ A E K
Sbjct: 129 YNTNNPNYTVAQFSPDDNSQNSMLEGAERVAELYQIEKADLDFWVKESHKRAKEAREEKI 188
Query: 374 FVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNASTLNDGX 553
D + P+ ++ +++ ++ ++ KE T A N+ +NDG
Sbjct: 189 LEDIISPINNST--------CDEGIRDKMSQRLLDRMPSILGKETIT-NAANSCLINDGA 239
Query: 554 XXXXXXXXXXXKRLNVKPIARIV 622
+ + KP A+I+
Sbjct: 240 SFIIICSKKYLEHVKKKPKAKII 262
>UniRef50_Q13HG7 Cluster: Acetyl-CoA C-acetyltransferase; n=1;
Burkholderia xenovorans LB400|Rep: Acetyl-CoA
C-acetyltransferase - Burkholderia xenovorans (strain
LB400)
Length = 265
Score = 52.0 bits (119), Expect = 1e-05
Identities = 25/64 (39%), Positives = 31/64 (48%)
Frame = +2
Query: 458 VNFEKFTKLSTVFQKENGTVTAGNASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADG 637
V E +L F ENGTVTAGNAS +ND + KP+AR+V +A
Sbjct: 107 VTLEDMMRLKPAFVMENGTVTAGNASGINDAAAALVLMEHIAAEERGTKPLARLVAYAHA 166
Query: 638 ECDP 649
DP
Sbjct: 167 GVDP 170
Score = 40.3 bits (90), Expect = 0.041
Identities = 25/89 (28%), Positives = 42/89 (47%), Gaps = 2/89 (2%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFY--LK 175
A I G + VN+ C SG++ ++ A+Q + G I + GG E+MS P+
Sbjct: 18 AAIEGGCSEGIPAFNVNRRCGSGLRPVISASQSIVPGDTEIAIGGGAENMSRTPYIAAAA 77
Query: 176 RGETSYGGMQLVDGIVFDGLTDVYNKFHM 262
R G ++D ++ L D ++ HM
Sbjct: 78 RWGARMGDSTMID-MMPGALHDPFHGIHM 105
>UniRef50_A5WF94 Cluster: Acetyl-CoA acetyltransferase; n=72;
Bacteria|Rep: Acetyl-CoA acetyltransferase -
Psychrobacter sp. PRwf-1
Length = 608
Score = 51.6 bits (118), Expect = 2e-05
Identities = 57/219 (26%), Positives = 94/219 (42%), Gaps = 19/219 (8%)
Frame = +2
Query: 23 PKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPF---------YLK 175
P++P V++ C +G+++ A+ + G + GG+++ S+ P +K
Sbjct: 260 PQTPAYD-VSQACGTGLQATFAASNKIALGIIDSAITGGVDTTSDAPIAVGDGLRKALIK 318
Query: 176 RGETSYGGMQL--VDGIVFDGLTDVYNK------FHMGNCAENTAKKLQITRQDQDEYAV 331
G +L + I L D MG+ TA + I+R+ QDE AV
Sbjct: 319 LGAARNNKQRLSALTSINPKELIDAPQNGEPRTGLSMGDHQAITALEWNISREAQDELAV 378
Query: 332 NSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENG 511
S++ A AYE + F D+L+ P K + ++ + EK L VF K N
Sbjct: 379 KSHQNLARAYE-EGFFDDLI---TPYKG----LTRDNNLRPDSSLEKLATLKPVFGKRNA 430
Query: 512 --TVTAGNASTLNDGXXXXXXXXXXXXKRLNVKPIARIV 622
T+TA N++ L DG + +KP+A IV
Sbjct: 431 NPTMTAANSTPLTDGASCVLLGTDEWAEAHGLKPLAYIV 469
>UniRef50_A5V6H6 Cluster: Thiolase; n=5; Proteobacteria|Rep:
Thiolase - Sphingomonas wittichii RW1
Length = 403
Score = 50.0 bits (114), Expect = 5e-05
Identities = 52/215 (24%), Positives = 88/215 (40%), Gaps = 8/215 (3%)
Frame = +2
Query: 41 PTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSYGGMQLVDGI 220
PT+ + CA+ ++ + L+A ++ +L + +SN P L GG +V+
Sbjct: 83 PTIAQACATSVRCLALSAGQIEREQARTVLVVAADRISNGPTLLYPQPGGQGGQPVVERW 142
Query: 221 VFDGLT-DVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKR-SAAAYEAKAFVDELVP 394
+ D D M AEN A+ I+ ++Q E + ++ AA + AF+ +
Sbjct: 143 ILDNFAGDPNTSLAMIATAENAARSFGISTEEQHELVLMRLEQYRAALADDSAFLRLFMA 202
Query: 395 VP--VPQKRGAPVIFAEDEEYKRV--NFEKFTKLSTVFQKENGTVTAGNASTLNDGXXXX 562
+P +P +R + A + V ++ +LS V E GTVT + DG
Sbjct: 203 LPFDLPDRRFLDIADAVSGDVGVVASTRDRLAELSPVV--EGGTVTFAAQTHPADGNAGM 260
Query: 563 XXXXXXXXKRLNVKP-IA-RIVGFADGECDPIDFP 661
L+ KP IA R+ F P P
Sbjct: 261 IVASRERAAELSAKPGIAIRLRAFGQARAKPAFMP 295
>UniRef50_A1W8A4 Cluster: Acetyl-CoA acetyltransferases; n=3;
Comamonadaceae|Rep: Acetyl-CoA acetyltransferases -
Acidovorax sp. (strain JS42)
Length = 389
Score = 49.2 bits (112), Expect = 9e-05
Identities = 39/128 (30%), Positives = 60/128 (46%)
Frame = +2
Query: 14 AGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSY 193
AGLP+ T++ C +G+ ++ A L G +++AGG E+ S P + R +
Sbjct: 71 AGLPEGIPAVTLDSQCCAGLDAVTHACGLLALGQADVVVAGGAEAWSRAPLRMHRPLQAE 130
Query: 194 GGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKA 373
D F M A + A++L +TR QD YA+ S+ RS AA A A
Sbjct: 131 EAPVPYDRPPFTPWP--ARDPDMLLAALDGARRLGLTRHAQDAYAMASHARSVAARAAMA 188
Query: 374 FVDELVPV 397
E+VP+
Sbjct: 189 --HEIVPL 194
>UniRef50_UPI000065EB0A Cluster: 3-ketoacyl-CoA thiolase,
peroxisomal precursor (EC 2.3.1.16) (Beta- ketothiolase)
(Acetyl-CoA acyltransferase) (Peroxisomal 3-oxoacyl-CoA
thiolase).; n=1; Takifugu rubripes|Rep: 3-ketoacyl-CoA
thiolase, peroxisomal precursor (EC 2.3.1.16) (Beta-
ketothiolase) (Acetyl-CoA acyltransferase) (Peroxisomal
3-oxoacyl-CoA thiolase). - Takifugu rubripes
Length = 320
Score = 48.8 bits (111), Expect = 1e-04
Identities = 32/103 (31%), Positives = 53/103 (51%), Gaps = 5/103 (4%)
Frame = +2
Query: 257 HMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVP--VPQKRGAP-- 424
H +E A+K QI+R+ QD +A+ S ++A A + E++PV V G
Sbjct: 115 HRSITSEKVAEKFQISREKQDAFALRSQLKAAWAQSLGLYQQEIIPVTTKVVDADGTERL 174
Query: 425 VIFAEDEEYK-RVNFEKFTKLSTVFQKENGTVTAGNASTLNDG 550
V ++D+ + + + KL F K G+ TAGN+S ++DG
Sbjct: 175 VTVSQDDGIRGETSLARLAKLRPAF-KPGGSTTAGNSSQVSDG 216
>UniRef50_UPI00006A0465 Cluster: 3-ketoacyl-CoA thiolase,
peroxisomal precursor (EC 2.3.1.16) (Beta- ketothiolase)
(Acetyl-CoA acyltransferase) (Peroxisomal 3-oxoacyl-CoA
thiolase).; n=1; Xenopus tropicalis|Rep: 3-ketoacyl-CoA
thiolase, peroxisomal precursor (EC 2.3.1.16) (Beta-
ketothiolase) (Acetyl-CoA acyltransferase) (Peroxisomal
3-oxoacyl-CoA thiolase). - Xenopus tropicalis
Length = 329
Score = 48.0 bits (109), Expect = 2e-04
Identities = 31/90 (34%), Positives = 46/90 (51%), Gaps = 5/90 (5%)
Frame = +2
Query: 272 AENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPV----PQKRGAPVIFAE 439
+EN A++ ITR+ QD A+ S +R+AAA + F +E+VP+ Q + E
Sbjct: 150 SENVAERFGITREKQDSLALASQQRAAAAQRSGRFKEEIVPITTTFTDDQGNTKTITVTE 209
Query: 440 DEEYK-RVNFEKFTKLSTVFQKENGTVTAG 526
DE + E +L F KE G+ TAG
Sbjct: 210 DEGIRASTTMEGLGRLKAAF-KEGGSTTAG 238
>UniRef50_A3N0P7 Cluster: 3-ketoacyl-CoA thiolase; n=1;
Actinobacillus pleuropneumoniae L20|Rep: 3-ketoacyl-CoA
thiolase - Actinobacillus pleuropneumoniae serotype 5b
(strain L20)
Length = 434
Score = 48.0 bits (109), Expect = 2e-04
Identities = 49/215 (22%), Positives = 86/215 (40%), Gaps = 19/215 (8%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVP--------------FYLKRG 181
+++ C SG+++I A + +G+ +AGG +S+SN P F +
Sbjct: 92 SISSSCLSGLQAIANVAGSIVSGSISAGIAGGADSISNAPLSISPRVIYKLKSIFNAETL 151
Query: 182 ETSYGGMQLVDGIVFD----GLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRS 349
E Y + L D + + +E A+ I+R +QDEYA S +R+
Sbjct: 152 EEKYRRFRHFSWRDLKPHGVNLRDFTTQMSVAEVSEQMAQDNHISRAEQDEYARLSNQRA 211
Query: 350 AAAYEAKAFVDELVP-VPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAG 526
+ A++ +E++P P P K + ++ + + S + KE TVT
Sbjct: 212 SDAWKIGLLKEEVMPSFPRPYK---DFVVSDTLISAATRASYYQRFSPIVDKEYATVTEA 268
Query: 527 NASTLNDGXXXXXXXXXXXXKRLNVKPIARIVGFA 631
N DG K L + P+ I +A
Sbjct: 269 NMPQPMDGAAAVLLMNESRAKALGLMPLGYIRSYA 303
>UniRef50_Q1GCU4 Cluster: Acetyl-CoA C-acetyltransferase; n=2;
Rhodobacterales|Rep: Acetyl-CoA C-acetyltransferase -
Silicibacter sp. (strain TM1040)
Length = 367
Score = 47.2 bits (107), Expect = 4e-04
Identities = 55/218 (25%), Positives = 91/218 (41%), Gaps = 2/218 (0%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A + AGLP ++++ CA G+ +I+L +Q G +++AGG ES S P +R
Sbjct: 65 AALAAGLPDHVAGLSIDRQCAGGLDAILLGHALVQAGHHEVVIAGGAESYSRRP---QRS 121
Query: 182 ETSYGGM--QLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAA 355
T G + F D M A + A+ ITR +QD++A S+ A+
Sbjct: 122 RTFADGRPPEPYAQARFTPWPD--RDPDMAVAAADLARMQHITRAEQDDWAQRSH-ALAS 178
Query: 356 AYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNAS 535
+EA+ +E+V + GA +D + + + V G +TA N +
Sbjct: 179 LHEARR-AEEIVSI-----NGA----VKDSFTRTLTARHCARAKVV----TGDITAANMA 224
Query: 536 TLNDGXXXXXXXXXXXXKRLNVKPIARIVGFADGECDP 649
D +RL + ++ I G G DP
Sbjct: 225 VAADAAAFVVIVSEKIARRLRTRGLSLIAGATLG-ADP 261
>UniRef50_Q1GUF0 Cluster: Acetyl-CoA C-acyltransferase; n=2;
Proteobacteria|Rep: Acetyl-CoA C-acyltransferase -
Sphingopyxis alaskensis (Sphingomonas alaskensis)
Length = 386
Score = 46.4 bits (105), Expect = 6e-04
Identities = 23/55 (41%), Positives = 33/55 (60%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPF 166
A + A LP + ++N CASG+ +I LA + +G + LAGG+ESMS PF
Sbjct: 72 AKLHADLPDTMAAHSLNNYCASGLTAIGLAVAKVASGEIDVALAGGVESMSAAPF 126
>UniRef50_A6RBW5 Cluster: Putative uncharacterized protein; n=1;
Ajellomyces capsulatus NAm1|Rep: Putative
uncharacterized protein - Ajellomyces capsulatus NAm1
Length = 228
Score = 46.4 bits (105), Expect = 6e-04
Identities = 30/104 (28%), Positives = 53/104 (50%), Gaps = 7/104 (6%)
Frame = +2
Query: 260 MGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPV----PQKRGAPV 427
+G+ +EN A + I+R+ D++A S++R+ A ++ VDE+ P+ V P+
Sbjct: 72 LGHTSENVAGQFNISREKMDDFAARSHQRAELAQKSGWVVDEIAPIRVKVKDPKTGQVRE 131
Query: 428 IFAEDEEYKR--VNFEKFTKLSTVF-QKENGTVTAGNASTLNDG 550
+ A+ ++ R E K+ F Q + G T GNAS + G
Sbjct: 132 VVADRDDGIRYGTTAESLAKVRPAFSQWKPGRTTGGNASQITGG 175
>UniRef50_Q4TEZ0 Cluster: Chromosome undetermined SCAF4980, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF4980,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 122
Score = 46.0 bits (104), Expect = 8e-04
Identities = 22/35 (62%), Positives = 25/35 (71%)
Frame = +2
Query: 14 AGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQ 118
+GL S T+NKVCASGMKSIM+AAQ L G Q
Sbjct: 1 SGLSLSTPATTINKVCASGMKSIMMAAQSLMCGHQ 35
>UniRef50_Q1M689 Cluster: Putative thiolase; n=1; Rhizobium
leguminosarum bv. viciae 3841|Rep: Putative thiolase -
Rhizobium leguminosarum bv. viciae (strain 3841)
Length = 143
Score = 45.6 bits (103), Expect = 0.001
Identities = 22/73 (30%), Positives = 40/73 (54%)
Frame = +2
Query: 251 KFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVI 430
+F G+ E + L ++R+DQ +AV S ++A A + E+ V +P+++GAPV+
Sbjct: 53 RFDAGDRRERR-RGLSVSREDQYAFAVRSQAKAAVAQASGRLAKEITSVTIPRRKGAPVV 111
Query: 431 FAEDEEYKRVNFE 469
+DE + E
Sbjct: 112 VDKDEHPRATTME 124
>UniRef50_A7IGV8 Cluster: Acetyl-CoA acetyltransferase; n=1;
Xanthobacter autotrophicus Py2|Rep: Acetyl-CoA
acetyltransferase - Xanthobacter sp. (strain Py2)
Length = 376
Score = 45.2 bits (102), Expect = 0.001
Identities = 31/118 (26%), Positives = 51/118 (43%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
A + AGLP+ T++ C SG+ +I + A + G +LAGG+ES S P R
Sbjct: 67 AALAAGLPQHVPALTLDTQCCSGLDAIRMGAARIAAGEARYVLAGGVESFSRAPLRAHRP 126
Query: 182 ETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAA 355
F + + + A A+ I R Q+ +A+ S++R+ A
Sbjct: 127 RNKDEAPAFYRQPAFTPWPE--REPDLAAAAAELARAEGIPRPAQEAFAMESHRRALA 182
>UniRef50_UPI000023DFFE Cluster: hypothetical protein FG09503.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG09503.1 - Gibberella zeae PH-1
Length = 380
Score = 43.2 bits (97), Expect = 0.006
Identities = 28/107 (26%), Positives = 52/107 (48%), Gaps = 5/107 (4%)
Frame = +2
Query: 317 DEYAVNSYKRSAAAYEAKAFVDELVPVPVP--QKRG--APVIFAEDEEYKR-VNFEKFTK 481
D +A +SY+++ A + F +E+ P+ V K G + ++D+ + + E K
Sbjct: 159 DTFAASSYQKALKAQKEGLFDEEIAPLKVKFEDKEGNTKEITVSKDDGVREGITVESLGK 218
Query: 482 LSTVFQKENGTVTAGNASTLNDGXXXXXXXXXXXXKRLNVKPIARIV 622
+ F K+ G++ AGNAS ++DG ++L K I + V
Sbjct: 219 IRPAFAKD-GSIHAGNASQISDGAAAVLLMKRSTAEKLGQKIIGKYV 264
Score = 39.9 bits (89), Expect = 0.054
Identities = 19/51 (37%), Positives = 32/51 (62%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMS 154
A + AG P+S T+N+ C+SG+++ + A ++TG I + G+ESMS
Sbjct: 100 ASLVAGFPESIAVRTLNRQCSSGLQATVDVANQIKTGMIDIGIGAGVESMS 150
>UniRef50_UPI00006D84CA Cluster: COG0183: Acetyl-CoA
acetyltransferase; n=1; Pseudomonas aeruginosa
C3719|Rep: COG0183: Acetyl-CoA acetyltransferase -
Pseudomonas aeruginosa C3719
Length = 131
Score = 41.5 bits (93), Expect = 0.018
Identities = 19/39 (48%), Positives = 26/39 (66%)
Frame = +2
Query: 2 AVIFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQ 118
AV+ AGL + C T+NK+C SGMK++MLA L A+
Sbjct: 72 AVLGAGLARGTPCSTLNKMCGSGMKALMLAHDTLLAAAR 110
>UniRef50_A3K5J3 Cluster: Acetyl-CoA acetyltransferase; n=1;
Sagittula stellata E-37|Rep: Acetyl-CoA
acetyltransferase - Sagittula stellata E-37
Length = 408
Score = 41.1 bits (92), Expect = 0.024
Identities = 32/117 (27%), Positives = 50/117 (42%), Gaps = 1/117 (0%)
Frame = +2
Query: 272 AENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAP-VIFAEDEE 448
AE A + I R D YA S+ R + A A E+VP + GA + A D
Sbjct: 163 AEAAAYRFGIDRASADAYAAQSHARLSDAMTAGRTDAEVVP-----RFGADGTVSARDCA 217
Query: 449 YKRVNFEKFTKLSTVFQKENGTVTAGNASTLNDGXXXXXXXXXXXXKRLNVKPIARI 619
RV+ E+ ++L+ G+VT GNA+ +G + P+A++
Sbjct: 218 LARVSAERLSRLTPASGSPFGSVTTGNAAVPGEGACWLMIASDAAVDAFGLTPLAKV 274
>UniRef50_Q7NDK9 Cluster: Gll4226 protein; n=1; Gloeobacter
violaceus|Rep: Gll4226 protein - Gloeobacter violaceus
Length = 3029
Score = 40.3 bits (90), Expect = 0.041
Identities = 43/134 (32%), Positives = 64/134 (47%), Gaps = 10/134 (7%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGME-SMSNVPFYL--KRGETSYGGM---- 202
TV+ CAS + +I LA + L+TG +++AGG++ S P++ K + GG
Sbjct: 879 TVDAACASSLAAIHLAVRDLETGHSAMVIAGGVDTSQGPFPYFCFSKTQALTPGGKPRPF 938
Query: 203 -QLVDGIVF-DGLTDVYNKFHMGNCAENTAKKLQITRQDQDE-YAVNSYKRSAAAYEAKA 373
Q DGIV +GL V K+L +D D YAV K +A + + KA
Sbjct: 939 DQAADGIVIGEGLAMV------------VLKRLADAERDGDRIYAV--IKSTAGSSDGKA 984
Query: 374 FVDELVPVPVPQKR 415
+ P+P QKR
Sbjct: 985 -LGMTAPLPAGQKR 997
>UniRef50_A6EZZ3 Cluster: Beta-ketoadipyl CoA thiolase PcaF; n=1;
Marinobacter algicola DG893|Rep: Beta-ketoadipyl CoA
thiolase PcaF - Marinobacter algicola DG893
Length = 127
Score = 40.3 bits (90), Expect = 0.041
Identities = 22/80 (27%), Positives = 45/80 (56%), Gaps = 6/80 (7%)
Frame = +2
Query: 89 AAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSYGGMQLVDG------IVFDGLTDVYN 250
A++ ++ G ++LAGG++SMS+ P+ + + +++Y Q V+G V + Y+
Sbjct: 7 ASRAIRAGEMNLVLAGGVQSMSHEPYVMGKADSTYSRGQPVEGNTIGWRFVNPLMKKQYD 66
Query: 251 KFHMGNCAENTAKKLQITRQ 310
M AE A++ Q++R+
Sbjct: 67 IDSMPETAEKVAEQYQVSRE 86
>UniRef50_Q96X18 Cluster: Acetyl-CoA acetyltransferase; n=1;
Laccaria bicolor|Rep: Acetyl-CoA acetyltransferase -
Laccaria bicolor (Bicoloured deceiver) (Laccaria laccata
var.bicolor)
Length = 407
Score = 39.9 bits (89), Expect = 0.054
Identities = 18/46 (39%), Positives = 28/46 (60%)
Frame = +2
Query: 260 MGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPV 397
MG +EN A I R QD ++ S++++AAA +A F E+VP+
Sbjct: 165 MGITSENVAADYHIPRSTQDAFSAKSFQKAAAANKAGKFKSEIVPI 210
>UniRef50_Q3D2X0 Cluster: Thiolase; n=7; Streptococcus
agalactiae|Rep: Thiolase - Streptococcus agalactiae H36B
Length = 371
Score = 39.1 bits (87), Expect = 0.095
Identities = 40/168 (23%), Positives = 72/168 (42%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIV 223
T++ CAS ++ + TG +L GG+ES S P E + G + V
Sbjct: 81 TIDMQCASSSSALFFGYLKISTGINEKVLVGGIESSSLQPMRRYAKEDNRNG----EYTV 136
Query: 224 FDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPV 403
D Y + M A+ +K R+ D+ A S+KR+ A + +++E++ +P+
Sbjct: 137 AQFSPDSYAETVMLEGAQRVCQKYGFRREMLDKLAFLSHKRALTAKQG-GYLEEVI-LPM 194
Query: 404 PQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNASTLND 547
R V + K F+K +L + + +T GN ++D
Sbjct: 195 EGMRDQGV-----RKLKETFFQKLPRL----MENSPLLTIGNVCLMHD 233
>UniRef50_Q84FL0 Cluster: AdmM; n=4; Gammaproteobacteria|Rep: AdmM -
Enterobacter agglomerans (Erwinia herbicola) (Pantoea
agglomerans)
Length = 877
Score = 38.7 bits (86), Expect = 0.13
Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 1/92 (1%)
Frame = +2
Query: 47 VNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVF 226
V C+SG+ S+ +A QG+ TG + +AGG + +P+ L G GM L + V
Sbjct: 158 VQSACSSGLLSVHMAMQGIATGDCDMAIAGG----ACLPYPLHSGYQFQPGMNLSESGVL 213
Query: 227 DGLTDVYNKFHMG-NCAENTAKKLQITRQDQD 319
+ + G C K L R D+D
Sbjct: 214 SSYSHTADGMVPGFGCVVFVLKSLDKARSDKD 245
>UniRef50_Q5VKR9 Cluster: Ketoacyl-ACP synthase; n=2;
Saccharopolyspora erythraea|Rep: Ketoacyl-ACP synthase -
Saccharopolyspora erythraea (Streptomyces erythraeus)
Length = 405
Score = 38.7 bits (86), Expect = 0.13
Identities = 16/37 (43%), Positives = 24/37 (64%)
Frame = +2
Query: 38 CPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMES 148
C TV CASG +++ AAQ ++ G ++LAGG E+
Sbjct: 149 CTTVTTACASGADALVAAAQMIRLGEADVVLAGGAEA 185
>UniRef50_A4KCE5 Cluster: Tautomycetin biosynthetic PKS; n=1;
Streptomyces sp. CK4412|Rep: Tautomycetin biosynthetic
PKS - Streptomyces sp. CK4412
Length = 7620
Score = 37.9 bits (84), Expect = 0.22
Identities = 21/53 (39%), Positives = 31/53 (58%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSYGGM 202
+V+ C+S M S+ LAAQ L+ G + LAGG+ M+ ++ G T GGM
Sbjct: 5996 SVDTACSSSMVSMHLAAQALRAGECSLALAGGVTVMAEPDVFI--GFTVQGGM 6046
Score = 35.5 bits (78), Expect = 1.2
Identities = 18/53 (33%), Positives = 32/53 (60%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSYGGM 202
+V+ C+S + ++ LAAQ L+ G + LAGG+ M+ ++ G T+ GG+
Sbjct: 2274 SVDTACSSSLVAMHLAAQALRAGECSLALAGGVTVMATADAFV--GFTAQGGL 2324
>UniRef50_Q93NX9 Cluster: AmphI; n=5; Bacteria|Rep: AmphI -
Streptomyces nodosus
Length = 9510
Score = 37.5 bits (83), Expect = 0.29
Identities = 21/58 (36%), Positives = 33/58 (56%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSYGGMQLVDG 217
TV+ C+S + ++ LA Q L+ G + LAGG+ MS +++ G GG+ VDG
Sbjct: 190 TVDTACSSSLVAVHLATQALRAGECTLALAGGVTVMSGPGTFIEMGR--QGGLS-VDG 244
Score = 33.5 bits (73), Expect = 4.7
Identities = 15/37 (40%), Positives = 22/37 (59%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMS 154
T++ C+S + +I LA Q L+ G + LAGG MS
Sbjct: 5020 TLDTACSSSLVAIHLACQSLRNGESTLALAGGASIMS 5056
Score = 33.1 bits (72), Expect = 6.2
Identities = 15/37 (40%), Positives = 25/37 (67%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMS 154
+V+ C+S + ++ LAAQ L++G I LAGG+ M+
Sbjct: 8096 SVDTACSSSLVALHLAAQALRSGECSIALAGGVTVMA 8132
>UniRef50_Q0QMN6 Cluster: Polyketide synthase type I; n=1;
Streptomyces sp. Eco86|Rep: Polyketide synthase type I -
Streptomyces sp. Eco86
Length = 3422
Score = 37.5 bits (83), Expect = 0.29
Identities = 18/42 (42%), Positives = 28/42 (66%), Gaps = 1/42 (2%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSN-VPF 166
TV+ C+S + ++ LAAQ L++G + LAGG+ MS+ PF
Sbjct: 1872 TVDTACSSSLVALHLAAQSLRSGESALALAGGVTIMSSPTPF 1913
>UniRef50_A5KPS6 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus torques ATCC 27756|Rep: Putative
uncharacterized protein - Ruminococcus torques ATCC 27756
Length = 2160
Score = 37.5 bits (83), Expect = 0.29
Identities = 37/138 (26%), Positives = 58/138 (42%), Gaps = 10/138 (7%)
Frame = +2
Query: 137 GMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLT----DVYNKFHMGNCAENTAKKLQIT 304
G E N+ F LKR E +++G+ +G+T D K N +N +++T
Sbjct: 1098 GEEYKDNLYFILKREEDDQERKVMLEGLEKEGITYEIEDEEGKNSFENYTDNRVVTVKLT 1157
Query: 305 RQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVI------FAEDEEYKRVNF 466
DQD+Y + Y + + +E V + APVI D ++K +N
Sbjct: 1158 FDDQDKYEIKPY--CVDMFGNEGTTEETYKFAVDTE--APVIEYTYEYLDADNKWKPLND 1213
Query: 467 EKFTKLSTVFQKENGTVT 520
E KL + N TVT
Sbjct: 1214 ENAVKLKNAPIRVNVTVT 1231
>UniRef50_Q5XDB2 Cluster: Acetyl-CoA acetyltransferase; n=11;
Streptococcus pyogenes|Rep: Acetyl-CoA acetyltransferase
- Streptococcus pyogenes serotype M6
Length = 384
Score = 37.1 bits (82), Expect = 0.38
Identities = 31/139 (22%), Positives = 61/139 (43%), Gaps = 2/139 (1%)
Frame = +2
Query: 8 IFAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGET 187
+++ L +S TV+ CAS ++ + ++ G +L GG+ES S P E+
Sbjct: 68 LYSHLGESVSALTVDMQCASAGAALSVGYAKIKAGMASNLLVGGIESSSLQP------ES 121
Query: 188 SYGGMQLVDGI--VFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAY 361
Y G V D + F M AE A++ T++ + + + S+++++
Sbjct: 122 VYASADWRQGAYKVAQFSPDSISPFAMIEGAERVAREHGFTKEYLNHWTLRSHQKASYCQ 181
Query: 362 EAKAFVDELVPVPVPQKRG 418
E D ++ +P +G
Sbjct: 182 EQALLADLILDLPGASDQG 200
>UniRef50_Q3A171 Cluster: 3-oxoacyl-(Acyl-carrier-protein) synthase;
n=1; Pelobacter carbinolicus DSM 2380|Rep:
3-oxoacyl-(Acyl-carrier-protein) synthase - Pelobacter
carbinolicus (strain DSM 2380 / Gra Bd 1)
Length = 395
Score = 37.1 bits (82), Expect = 0.38
Identities = 16/41 (39%), Positives = 25/41 (60%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPF 166
TV C+SG ++ +A LQ G ++LAGG + +S VP+
Sbjct: 151 TVVNACSSGSDAVGIAMSWLQQGLCDVVLAGGTDELSMVPY 191
>UniRef50_A1GD41 Cluster: Acyl transferase region; n=1; Salinispora
arenicola CNS205|Rep: Acyl transferase region -
Salinispora arenicola CNS205
Length = 3508
Score = 36.7 bits (81), Expect = 0.51
Identities = 21/58 (36%), Positives = 33/58 (56%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSYGGMQLVDG 217
TV+ C+S + S+ LA Q L+ G + LAGG+ M+ +L E+S G+ +DG
Sbjct: 194 TVDTACSSSLVSLHLAVQSLRRGECSMALAGGVALMATPAMFL---ESSGQGVLALDG 248
>UniRef50_Q93NW6 Cluster: AmphC; n=1; Streptomyces nodosus|Rep: AmphC
- Streptomyces nodosus
Length = 10917
Score = 36.3 bits (80), Expect = 0.67
Identities = 22/55 (40%), Positives = 31/55 (56%), Gaps = 4/55 (7%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSN----VPFYLKRGETSYG 196
TV+ C+S + + LAAQ L+TG + LAGG+ MS V F +RG + G
Sbjct: 1927 TVDTACSSSLVGMHLAAQALRTGECTLALAGGVTVMSTPSTFVDFSRQRGLAADG 1981
Score = 34.7 bits (76), Expect = 2.0
Identities = 16/37 (43%), Positives = 25/37 (67%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMS 154
TV+ C+S + ++ LAAQ L+TG + LAGG+ +S
Sbjct: 9248 TVDTACSSSLVAMHLAAQALRTGECSLALAGGVTVIS 9284
Score = 34.3 bits (75), Expect = 2.7
Identities = 15/37 (40%), Positives = 25/37 (67%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMS 154
T++ C+S + ++ LAAQ L++G + LAGG+ MS
Sbjct: 5740 TIDTACSSALVAMHLAAQALRSGECSLALAGGVTVMS 5776
Score = 33.1 bits (72), Expect = 6.2
Identities = 15/44 (34%), Positives = 27/44 (61%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLK 175
TV+ C+S + ++ AAQ L++G + LAGG+ MS +++
Sbjct: 3666 TVDTACSSSLVALHWAAQALRSGECSLALAGGVTVMSTPSTFIE 3709
>UniRef50_Q9S0R3 Cluster: Type I polyketide synthase AVES 4; n=2;
Streptomyces|Rep: Type I polyketide synthase AVES 4 -
Streptomyces avermitilis
Length = 4881
Score = 35.9 bits (79), Expect = 0.88
Identities = 16/44 (36%), Positives = 26/44 (59%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLK 175
TV+ C+S + ++ LA Q L+TG LAGG+ MS +++
Sbjct: 201 TVDTACSSSLVALHLACQSLRTGESSFALAGGVTVMSTPGMFVE 244
Score = 33.5 bits (73), Expect = 4.7
Identities = 15/37 (40%), Positives = 24/37 (64%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMS 154
TV+ C+S + ++ LA Q L++G + LAGG+ MS
Sbjct: 1758 TVDTACSSSLVALHLACQALRSGECSLALAGGVTVMS 1794
Score = 33.5 bits (73), Expect = 4.7
Identities = 15/37 (40%), Positives = 24/37 (64%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMS 154
TV+ C+S + ++ LA Q L++G + LAGG+ MS
Sbjct: 2803 TVDTACSSSLVALHLACQALRSGECSLALAGGVTVMS 2839
>UniRef50_Q9L4X3 Cluster: NysI; n=4; root|Rep: NysI - Streptomyces
noursei
Length = 9477
Score = 35.9 bits (79), Expect = 0.88
Identities = 20/58 (34%), Positives = 32/58 (55%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSYGGMQLVDG 217
TV+ C+S + ++ LA Q L+ G + LAGG+ MS +++ G GG+ DG
Sbjct: 190 TVDTACSSSLVAVHLATQALRAGECTLALAGGVTIMSGPGTFIEMGR--QGGLS-ADG 244
Score = 33.1 bits (72), Expect = 6.2
Identities = 14/37 (37%), Positives = 23/37 (62%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMS 154
T++ C+S + ++ LA Q L+ G + LAGG+ MS
Sbjct: 5067 TLDTACSSSLVAMHLACQSLRNGESSLALAGGVSIMS 5103
Score = 32.7 bits (71), Expect = 8.2
Identities = 15/37 (40%), Positives = 24/37 (64%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMS 154
+V+ C+S + ++ LAAQ L+ G I LAGG+ M+
Sbjct: 8067 SVDTACSSSLVALHLAAQALRAGECSIALAGGVTVMA 8103
>UniRef50_Q8RL72 Cluster: MmpIV; n=3; cellular organisms|Rep: MmpIV -
Pseudomonas fluorescens
Length = 6521
Score = 35.9 bits (79), Expect = 0.88
Identities = 18/49 (36%), Positives = 25/49 (51%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETS 190
TV+ C+S + +I +A Q L G + LAGG+ S FY K S
Sbjct: 2029 TVDTACSSALVAIHMACQSLLAGDTKVALAGGVFIQSTPAFYQKANRAS 2077
Score = 32.7 bits (71), Expect = 8.2
Identities = 15/53 (28%), Positives = 30/53 (56%)
Frame = +2
Query: 47 VNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSYGGMQ 205
V+ +C++ + +I LA QG+++G + LAGG+ + YL + ++ Q
Sbjct: 3548 VDSMCSASLTAIHLACQGIRSGDCDVALAGGVNVSVHPNKYLGLAQGNFASSQ 3600
>UniRef50_Q84HM3 Cluster: PksE; n=1; Lechevalieria
aerocolonigenes|Rep: PksE - Nocardia aerocolonigenes
(Lechevalieria aerocolonigenes)
Length = 1892
Score = 35.9 bits (79), Expect = 0.88
Identities = 19/61 (31%), Positives = 37/61 (60%), Gaps = 4/61 (6%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPF----YLKRGETSYGGMQLV 211
TV+ C+S + +++ A + L+ G+ ++LAGG++ +S PF + K G + G M++
Sbjct: 212 TVDGACSSALLAVVTACRSLRDGSADVVLAGGVD-LSVDPFELVGFAKTGALTAGPMRVY 270
Query: 212 D 214
D
Sbjct: 271 D 271
>UniRef50_Q6V1M7 Cluster: Plm2-3; n=1; Streptomyces sp. HK803|Rep:
Plm2-3 - Streptomyces sp. HK803
Length = 3362
Score = 35.9 bits (79), Expect = 0.88
Identities = 16/44 (36%), Positives = 27/44 (61%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLK 175
TV+ C+S + S+ LA Q L+ G + LAGG+ M+ F+++
Sbjct: 205 TVDTACSSSLVSLHLACQSLRAGECDLALAGGVAIMAGPTFFVE 248
>UniRef50_A4KCE4 Cluster: Tautomycetin biosynthetic PKS; n=2; cellular
organisms|Rep: Tautomycetin biosynthetic PKS -
Streptomyces sp. CK4412
Length = 9648
Score = 35.9 bits (79), Expect = 0.88
Identities = 19/53 (35%), Positives = 33/53 (62%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSYGGM 202
+V+ C+S + ++ LAAQ L++G + LAGG+ MS ++ G T+ GG+
Sbjct: 4425 SVDTACSSSLVAMHLAAQALRSGECSLALAGGVMVMSTPDAFV--GFTAQGGL 4475
Score = 35.9 bits (79), Expect = 0.88
Identities = 20/58 (34%), Positives = 34/58 (58%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSYGGMQLVDG 217
+V+ C+S + ++ LAAQ L++G + LAGG+ M+ ++ G T GG+ DG
Sbjct: 7750 SVDTACSSSLVAMHLAAQALRSGECSLALAGGVTVMATSDMFV--GLTKQGGLS-ADG 7804
Score = 35.5 bits (78), Expect = 1.2
Identities = 18/53 (33%), Positives = 32/53 (60%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSYGGM 202
+V+ C+S + ++ LAAQ L+ G + LAGG+ M+ ++ G T+ GG+
Sbjct: 2924 SVDTACSSSLVAMHLAAQALRAGECSLALAGGVTVMATADAFV--GFTAQGGL 2974
Score = 35.1 bits (77), Expect = 1.5
Identities = 16/44 (36%), Positives = 28/44 (63%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLK 175
+V+ C+S + ++ LAAQ L+TG + LAGG+ M+ +L+
Sbjct: 1241 SVDTACSSSLVAMHLAAQALRTGECNLALAGGVTVMATPEMFLE 1284
>UniRef50_A4FCY9 Cluster: Modular polyketide synthase; n=3; cellular
organisms|Rep: Modular polyketide synthase -
Saccharopolyspora erythraea (strain NRRL 23338)
Length = 4576
Score = 35.9 bits (79), Expect = 0.88
Identities = 17/38 (44%), Positives = 25/38 (65%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSN 157
TV+ C+S + ++ LAAQ LQ G + LAGG+ MS+
Sbjct: 2962 TVDTACSSSLVALHLAAQSLQRGECGLALAGGVTVMSS 2999
Score = 34.7 bits (76), Expect = 2.0
Identities = 16/46 (34%), Positives = 28/46 (60%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRG 181
TV+ C+S + ++ LA + L+ G + LAGG+ MSN +++ G
Sbjct: 1182 TVDTACSSSLVALHLAVEALRHGECELALAGGVTVMSNPGIFVEFG 1227
>UniRef50_A1YAM7 Cluster: Polyketide synthase type I; n=3;
Actinomycetales|Rep: Polyketide synthase type I -
Amycolatopsis orientalis
Length = 5723
Score = 35.9 bits (79), Expect = 0.88
Identities = 21/55 (38%), Positives = 32/55 (58%), Gaps = 4/55 (7%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSN----VPFYLKRGETSYG 196
TV+ C+S + ++ LAAQ L+ G + LAGG+ M+N V F +RG + G
Sbjct: 206 TVDTACSSSLVALHLAAQALRQGECSLALAGGVTVMANPAAFVDFSRQRGLAADG 260
Score = 33.5 bits (73), Expect = 4.7
Identities = 20/55 (36%), Positives = 31/55 (56%), Gaps = 4/55 (7%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSN----VPFYLKRGETSYG 196
TV+ C+S + ++ LAAQ L+ G + LAGG+ M+ V F +RG + G
Sbjct: 3795 TVDTACSSSLVALHLAAQALRQGECSLALAGGVTVMATPGTFVEFSRQRGLAADG 3849
Score = 33.1 bits (72), Expect = 6.2
Identities = 15/37 (40%), Positives = 24/37 (64%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMS 154
TV+ C+S + ++ LAAQ L+ G + LAGG+ M+
Sbjct: 1824 TVDTACSSSLVALHLAAQALRRGECSLALAGGVTVMA 1860
>UniRef50_A1GGE4 Cluster: Beta-ketoacyl synthase; n=1; Salinispora
arenicola CNS205|Rep: Beta-ketoacyl synthase -
Salinispora arenicola CNS205
Length = 5067
Score = 35.9 bits (79), Expect = 0.88
Identities = 17/37 (45%), Positives = 24/37 (64%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMS 154
TV+ C+S + S+ LAAQ L+ G + LAGG+ MS
Sbjct: 2833 TVDTACSSSLVSLHLAAQALRAGECSLALAGGVTVMS 2869
>UniRef50_Q92GI8 Cluster: Similarity to acetyl-CoA
acetyltransferase; n=2; Rickettsia|Rep: Similarity to
acetyl-CoA acetyltransferase - Rickettsia conorii
Length = 106
Score = 35.5 bits (78), Expect = 1.2
Identities = 14/26 (53%), Positives = 20/26 (76%)
Frame = +2
Query: 5 VIFAGLPKSPXCPTVNKVCASGMKSI 82
+I+AG+PK T+NKVC SG+KS+
Sbjct: 71 LIYAGIPKEVPGYTINKVCGSGLKSV 96
>UniRef50_Q6W5P6 Cluster: FscD; n=6; Bacteria|Rep: FscD - Streptomyces
sp. FR-008
Length = 9550
Score = 35.5 bits (78), Expect = 1.2
Identities = 17/42 (40%), Positives = 26/42 (61%), Gaps = 1/42 (2%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSN-VPF 166
TV+ C+S + ++ LA Q L+ G + LAGG M+N +PF
Sbjct: 3507 TVDTACSSSLVALHLACQSLRNGETTLALAGGATVMTNPMPF 3548
Score = 35.5 bits (78), Expect = 1.2
Identities = 16/47 (34%), Positives = 30/47 (63%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGE 184
+V+ C+S + ++ LAAQ +++G + LAGG+ MS +++ GE
Sbjct: 8093 SVDTACSSSLTALHLAAQAIRSGECSLALAGGVTVMSTPVGFVEFGE 8139
>UniRef50_Q3S864 Cluster: Nodular polyketide synthase; n=15;
Bacteria|Rep: Nodular polyketide synthase - Streptomyces
neyagawaensis
Length = 4970
Score = 35.5 bits (78), Expect = 1.2
Identities = 16/37 (43%), Positives = 25/37 (67%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMS 154
TV+ C+S + ++ LAAQ L++G + LAGG+ MS
Sbjct: 3298 TVDTACSSSLVAVHLAAQALRSGECTLALAGGVTVMS 3334
Score = 33.9 bits (74), Expect = 3.6
Identities = 15/36 (41%), Positives = 24/36 (66%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESM 151
TV+ C+S + ++ LAAQ L++G + LAGG+ M
Sbjct: 1745 TVDTACSSSLVAVHLAAQALRSGECSLALAGGVTVM 1780
>UniRef50_Q0QMQ1 Cluster: Polyketide synthase type I; n=1;
Streptomyces aculeolatus|Rep: Polyketide synthase type I
- Streptomyces aculeolatus
Length = 4308
Score = 35.5 bits (78), Expect = 1.2
Identities = 21/55 (38%), Positives = 33/55 (60%), Gaps = 4/55 (7%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSN----VPFYLKRGETSYG 196
TV+ C+S + ++ LAAQ L+TG + LAGG+ M+ V F +RG ++ G
Sbjct: 2946 TVDTACSSSLVALHLAAQSLRTGECDMALAGGVTVMAGPGTFVEFSRQRGLSADG 3000
>UniRef50_Q0P7K1 Cluster: Putative hybrid non-ribosomal
peptide-polyketide synthetase; n=5;
Enterobacteriaceae|Rep: Putative hybrid non-ribosomal
peptide-polyketide synthetase - Escherichia coli
Length = 2154
Score = 35.5 bits (78), Expect = 1.2
Identities = 21/63 (33%), Positives = 33/63 (52%), Gaps = 1/63 (1%)
Frame = +2
Query: 38 CPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGME-SMSNVPFYLKRGETSYGGMQLVD 214
C TV CA+ + ++ LA +GL +G + LAGG+ M Y G+ G+Q D
Sbjct: 160 CVTVQASCATSLVAVHLACEGLLSGQCDMALAGGVTFRMEEQRSYESHGD----GLQAED 215
Query: 215 GIV 223
G++
Sbjct: 216 GLI 218
>UniRef50_Q09DD1 Cluster: Type I polyketide synthase PikAI; n=1;
Stigmatella aurantiaca DW4/3-1|Rep: Type I polyketide
synthase PikAI - Stigmatella aurantiaca DW4/3-1
Length = 950
Score = 35.5 bits (78), Expect = 1.2
Identities = 26/92 (28%), Positives = 37/92 (40%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIV 223
TV CAS + ++ L+ QGL+ G LAGG+ S P+ + + G G
Sbjct: 693 TVESACASTLAALSLSIQGLRDGRWDAALAGGVWSQITAPYCV---NMCFVGAVSPTGET 749
Query: 224 FDGLTDVYNKFHMGNCAENTAKKLQITRQDQD 319
D H C K+L R+D D
Sbjct: 750 RPFSKDADGFVHGEGCGMFVLKRLSDARRDGD 781
>UniRef50_Q099Y5 Cluster: Oxidoreductase, short chain
dehydrogenase/reductase family; n=1; Stigmatella
aurantiaca DW4/3-1|Rep: Oxidoreductase, short chain
dehydrogenase/reductase family - Stigmatella aurantiaca
DW4/3-1
Length = 2274
Score = 35.5 bits (78), Expect = 1.2
Identities = 17/33 (51%), Positives = 20/33 (60%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGM 142
TV CAS + SI LA Q L TG + LAGG+
Sbjct: 330 TVEAACASSLVSIHLACQSLLTGESALALAGGV 362
>UniRef50_Q4P0A3 Cluster: Putative uncharacterized protein; n=2;
Eukaryota|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 3704
Score = 35.5 bits (78), Expect = 1.2
Identities = 17/41 (41%), Positives = 28/41 (68%)
Frame = +2
Query: 32 PXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMS 154
P PTV CA+ ++S+ +AA+ ++ G I++AGG ES+S
Sbjct: 3351 PIKPTVG-ACATALQSLDVAAETIRCGKAKIMIAGGYESIS 3390
>UniRef50_Q93HI8 Cluster: Modular polyketide synthase; n=1;
Streptomyces avermitilis|Rep: Modular polyketide synthase
- Streptomyces avermitilis
Length = 3970
Score = 35.1 bits (77), Expect = 1.5
Identities = 16/37 (43%), Positives = 25/37 (67%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMS 154
T++ C+S + ++ LAAQ L+TG + LAGG+ MS
Sbjct: 2004 TLDTACSSSLVALHLAAQALRTGECDLALAGGVTVMS 2040
>UniRef50_Q9EWA1 Cluster: PimS2 protein; n=2; Streptomyces|Rep: PimS2
protein - Streptomyces natalensis
Length = 9507
Score = 35.1 bits (77), Expect = 1.5
Identities = 17/47 (36%), Positives = 29/47 (61%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGE 184
+V+ C+S + ++ LAAQ L+ G I L GG+ MS+ +++ GE
Sbjct: 8064 SVDTACSSSLVALHLAAQALRNGECSIALTGGVTVMSSPVNFVEFGE 8110
Score = 34.7 bits (76), Expect = 2.0
Identities = 15/38 (39%), Positives = 23/38 (60%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSN 157
TV+ C+S + ++ LA Q L+ G + LAGG M+N
Sbjct: 3495 TVDTACSSSLVALHLACQSLRNGESSLALAGGATVMTN 3532
>UniRef50_Q846X2 Cluster: Monensin polyketide synthase modules 7 and
8; n=3; Streptomyces|Rep: Monensin polyketide synthase
modules 7 and 8 - Streptomyces cinnamonensis
Length = 4106
Score = 35.1 bits (77), Expect = 1.5
Identities = 17/37 (45%), Positives = 24/37 (64%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMS 154
TV+ C+S + SI LAAQ L+ G + LAGG+ M+
Sbjct: 2023 TVDTACSSSLVSIHLAAQALRQGECTLALAGGVTVMA 2059
>UniRef50_Q3W1C5 Cluster: Beta-ketoacyl synthase:Acyl transferase
domain:Phosphopantetheine- binding domain; n=1; Frankia
sp. EAN1pec|Rep: Beta-ketoacyl synthase:Acyl transferase
domain:Phosphopantetheine- binding domain - Frankia sp.
EAN1pec
Length = 1392
Score = 35.1 bits (77), Expect = 1.5
Identities = 16/44 (36%), Positives = 28/44 (63%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLK 175
TV+ C+S + ++ LAAQ L++G + LAGG+ M+ +L+
Sbjct: 249 TVDTACSSSLVALHLAAQALRSGECDLALAGGVTVMATPGMFLE 292
>UniRef50_Q3S863 Cluster: Modular polyketide synthase; n=1;
Streptomyces neyagawaensis|Rep: Modular polyketide
synthase - Streptomyces neyagawaensis
Length = 3982
Score = 35.1 bits (77), Expect = 1.5
Identities = 19/42 (45%), Positives = 26/42 (61%), Gaps = 1/42 (2%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSN-VPF 166
TV+ C+S + ++ LAAQ L+ G + LAGG MS VPF
Sbjct: 205 TVDTACSSSLVALHLAAQALRRGECGLALAGGAMIMSTPVPF 246
Score = 33.5 bits (73), Expect = 4.7
Identities = 20/55 (36%), Positives = 32/55 (58%), Gaps = 4/55 (7%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSN----VPFYLKRGETSYG 196
TV+ C+S + ++ LA + L++G + LAGG+ MS+ V F +RG S G
Sbjct: 1975 TVDTACSSSLVALHLAVRALRSGECGLALAGGVTVMSSPELFVEFSRQRGLASDG 2029
>UniRef50_Q0RLH1 Cluster: Putative polyketide synthase; n=1; Frankia
alni ACN14a|Rep: Putative polyketide synthase - Frankia
alni (strain ACN14a)
Length = 2295
Score = 35.1 bits (77), Expect = 1.5
Identities = 15/38 (39%), Positives = 24/38 (63%)
Frame = +2
Query: 38 CPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESM 151
C TV+ C+S + ++ LA+Q L+ G + LAGG+ M
Sbjct: 204 CLTVDTACSSSLVAVHLASQSLRAGECSVALAGGVTLM 241
>UniRef50_Q0QMP8 Cluster: Polyketide synthase type I; n=1;
Streptomyces aculeolatus|Rep: Polyketide synthase type I
- Streptomyces aculeolatus
Length = 3297
Score = 35.1 bits (77), Expect = 1.5
Identities = 16/38 (42%), Positives = 26/38 (68%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSN 157
TV+ C+S + ++ LAAQ L+TG + LAGG+ M++
Sbjct: 1957 TVDTACSSSLVALHLAAQSLRTGECDMALAGGVTVMAS 1994
>UniRef50_Q0QMN5 Cluster: Polyketide synthase type I; n=1;
Streptomyces sp. Eco86|Rep: Polyketide synthase type I -
Streptomyces sp. Eco86
Length = 5393
Score = 35.1 bits (77), Expect = 1.5
Identities = 16/44 (36%), Positives = 26/44 (59%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLK 175
TV+ C+S + ++ LA Q L+ G + LAGG+ MS Y++
Sbjct: 280 TVDTACSSSLVTLHLAVQSLRNGETSLALAGGVTIMSTPGTYVE 323
Score = 32.7 bits (71), Expect = 8.2
Identities = 15/44 (34%), Positives = 26/44 (59%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLK 175
TV+ C+S + ++ LAAQ L+ G + LAGG M+ +++
Sbjct: 2273 TVDTACSSSLVALHLAAQALRNGECDLALAGGATVMATPGLFVE 2316
Score = 32.7 bits (71), Expect = 8.2
Identities = 15/37 (40%), Positives = 23/37 (62%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMS 154
TV+ C+S + ++ LAAQ L+ G + LAGG M+
Sbjct: 3993 TVDTACSSSLVTLHLAAQALRAGECSLALAGGATVMA 4029
>UniRef50_A6GK65 Cluster: Polyketide synthase type I; n=2;
Plesiocystis pacifica SIR-1|Rep: Polyketide synthase
type I - Plesiocystis pacifica SIR-1
Length = 3091
Score = 35.1 bits (77), Expect = 1.5
Identities = 15/35 (42%), Positives = 21/35 (60%)
Frame = +2
Query: 38 CPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGM 142
C VN C+S + ++ LA Q L+ G I LAGG+
Sbjct: 221 CMVVNTACSSALVAVHLACQALRLGESQIALAGGV 255
>UniRef50_A4X8L0 Cluster: Beta-ketoacyl synthase; n=1; Salinispora
tropica CNB-440|Rep: Beta-ketoacyl synthase - Salinispora
tropica CNB-440
Length = 7210
Score = 35.1 bits (77), Expect = 1.5
Identities = 20/50 (40%), Positives = 30/50 (60%), Gaps = 4/50 (8%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSN----VPFYLKRG 181
+V+ C+S + +I LA Q L++G + LAGG+ MS V F L+RG
Sbjct: 3810 SVDTACSSSLVAIHLAVQALRSGECSLALAGGVTVMSTPDTFVEFSLQRG 3859
Score = 35.1 bits (77), Expect = 1.5
Identities = 20/50 (40%), Positives = 30/50 (60%), Gaps = 4/50 (8%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSN----VPFYLKRG 181
+V+ C+S + +I LA Q L++G + LAGG+ MS V F L+RG
Sbjct: 5549 SVDTACSSSLVAIHLAVQALRSGECSLALAGGVTVMSTPDTFVEFSLQRG 5598
>UniRef50_A1YAM9 Cluster: Polyketide synthase type I; n=5; cellular
organisms|Rep: Polyketide synthase type I - Amycolatopsis
orientalis
Length = 3264
Score = 35.1 bits (77), Expect = 1.5
Identities = 15/38 (39%), Positives = 25/38 (65%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSN 157
T++ C+S + ++ LAAQ L+ G + LAGG+ M+N
Sbjct: 1695 TIDTACSSSLVALHLAAQALRRGECSLALAGGVTVMAN 1732
Score = 33.1 bits (72), Expect = 6.2
Identities = 13/38 (34%), Positives = 25/38 (65%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSN 157
T++ C+S + ++ LAA+ L+ G + LAGG+ M++
Sbjct: 204 TIDTACSSSLVALHLAAESLRRGESTLALAGGVTVMAS 241
>UniRef50_Q58944 Cluster: Uncharacterized protein MJ1549; n=18;
Euryarchaeota|Rep: Uncharacterized protein MJ1549 -
Methanococcus jannaschii
Length = 392
Score = 35.1 bits (77), Expect = 1.5
Identities = 18/49 (36%), Positives = 27/49 (55%)
Frame = +2
Query: 14 AGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNV 160
AGL P V CASG ++ A + +GA ++L GG+E M++V
Sbjct: 71 AGLNPIPST-RVEAACASGSLALRQAVLNVASGASDVVLVGGVEKMTDV 118
>UniRef50_Q03132 Cluster: Erythronolide synthase, modules 3 and 4;
n=7; Actinomycetales|Rep: Erythronolide synthase, modules
3 and 4 - Saccharopolyspora erythraea (Streptomyces
erythraeus)
Length = 3567
Score = 35.1 bits (77), Expect = 1.5
Identities = 22/55 (40%), Positives = 30/55 (54%), Gaps = 4/55 (7%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSN----VPFYLKRGETSYG 196
TV+ C+S + I LA Q L+ G + LAGG+ MS+ V F +RG S G
Sbjct: 1656 TVDTACSSSLVGIHLAMQALRRGECSLALAGGVTVMSDPYTFVDFSTQRGLASDG 1710
>UniRef50_Q3ZXT9 Cluster: 3-oxoacyl-[acyl-carrier-protein] synthase
II; n=5; Chloroflexi|Rep:
3-oxoacyl-[acyl-carrier-protein] synthase II -
Dehalococcoides sp. (strain CBDB1)
Length = 422
Score = 34.7 bits (76), Expect = 2.0
Identities = 19/47 (40%), Positives = 27/47 (57%)
Frame = +2
Query: 17 GLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSN 157
GL S C T C+SG +I A + ++ G+ I+LAGG ES+ N
Sbjct: 156 GLKGSNFCTT--SACSSGSDAIGTAFEKIRFGSAKIVLAGGAESIMN 200
>UniRef50_Q9L4W3 Cluster: NysC; n=3; Actinomycetales|Rep: NysC -
Streptomyces noursei
Length = 11096
Score = 34.7 bits (76), Expect = 2.0
Identities = 16/37 (43%), Positives = 24/37 (64%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMS 154
TV+ C+S + ++ LAAQ L+ G + LAGG+ MS
Sbjct: 9379 TVDTACSSSLVALHLAAQALRAGECTLALAGGVTVMS 9415
Score = 33.9 bits (74), Expect = 3.6
Identities = 16/37 (43%), Positives = 24/37 (64%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMS 154
TV+ C+S + ++ LAAQ L+ G + LAGG+ MS
Sbjct: 5788 TVDTACSSSLVALHLAAQALRGGECTLALAGGVTVMS 5824
>UniRef50_Q76KY0 Cluster: Polyketide synthase modules 1-3; n=2;
cellular organisms|Rep: Polyketide synthase modules 1-3 -
Streptomyces halstedii
Length = 5826
Score = 34.7 bits (76), Expect = 2.0
Identities = 21/55 (38%), Positives = 31/55 (56%), Gaps = 4/55 (7%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSN----VPFYLKRGETSYG 196
TV+ C+S + ++ AAQ L+ G + LAGG+ MS V F L+RG + G
Sbjct: 4134 TVDTACSSSLVALHWAAQALRQGECSMALAGGVTVMSTPETFVDFSLQRGLATNG 4188
>UniRef50_Q6JHN6 Cluster: ObsC; n=1; Saccharopolyspora spinosa|Rep:
ObsC - Saccharopolyspora spinosa
Length = 7488
Score = 34.7 bits (76), Expect = 2.0
Identities = 16/37 (43%), Positives = 25/37 (67%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMS 154
TV+ C+S + ++ LAAQ L++G + LAGG+ MS
Sbjct: 1935 TVDTACSSSLVALHLAAQALRSGECDLALAGGVTVMS 1971
>UniRef50_Q3S868 Cluster: Modular polyketide synthase; n=1;
Streptomyces neyagawaensis|Rep: Modular polyketide
synthase - Streptomyces neyagawaensis
Length = 2056
Score = 34.7 bits (76), Expect = 2.0
Identities = 15/43 (34%), Positives = 25/43 (58%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYL 172
T++ C+S + ++ LA Q L+ G + LAGG+ MS Y+
Sbjct: 200 TIDTACSSSLVALHLACQALRAGEISLALAGGVTVMSTPSLYV 242
>UniRef50_Q1MX73 Cluster: Type I polyketide synthase; n=1;
Streptomyces sp. NRRL 11266|Rep: Type I polyketide
synthase - Streptomyces sp. NRRL 11266
Length = 5657
Score = 34.7 bits (76), Expect = 2.0
Identities = 17/44 (38%), Positives = 26/44 (59%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLK 175
TV+ C+S + + LAAQ L+ G + LAGG+ MS +L+
Sbjct: 4030 TVDTACSSSLVGMHLAAQALRNGECDLALAGGVTVMSTPSAFLE 4073
>UniRef50_Q1MX72 Cluster: Type I polyketide synthase; n=2;
Streptomyces sp. NRRL 11266|Rep: Type I polyketide
synthase - Streptomyces sp. NRRL 11266
Length = 5963
Score = 34.7 bits (76), Expect = 2.0
Identities = 16/38 (42%), Positives = 25/38 (65%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSN 157
TV+ C+S + ++ LAAQ L+ G + LAGG+ MS+
Sbjct: 2270 TVDTACSSSLVALHLAAQALRNGECDLALAGGVTVMSS 2307
>UniRef50_P95814 Cluster: FK506 polyketide synthase; n=2;
Streptomyces|Rep: FK506 polyketide synthase -
Streptomyces sp
Length = 6420
Score = 34.7 bits (76), Expect = 2.0
Identities = 20/55 (36%), Positives = 32/55 (58%), Gaps = 4/55 (7%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSN----VPFYLKRGETSYG 196
TV+ C+S + ++ LA QGL+ G + LAGG+ +S+ V F +RG + G
Sbjct: 5573 TVDTACSSSLVALHLACQGLRLGECELALAGGVSVLSSPAAFVEFSRQRGLAADG 5627
>UniRef50_A5IHN4 Cluster: 3-oxoacyl-(Acyl carrier protein) synthase
II, C-terminal; n=4; Legionella pneumophila|Rep:
3-oxoacyl-(Acyl carrier protein) synthase II, C-terminal
- Legionella pneumophila (strain Corby)
Length = 430
Score = 34.7 bits (76), Expect = 2.0
Identities = 16/38 (42%), Positives = 25/38 (65%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSN 157
+V+ CASG +++ LA Q ++ G +LAGG +SM N
Sbjct: 171 SVHTACASGGQALGLAMQVIRRGEADFMLAGGFDSMIN 208
>UniRef50_Q9L8C7 Cluster: Polyketide synthase; n=8; Sorangium
cellulosum|Rep: Polyketide synthase - Polyangium
cellulosum (Sorangium cellulosum)
Length = 7257
Score = 34.3 bits (75), Expect = 2.7
Identities = 14/38 (36%), Positives = 24/38 (63%)
Frame = +2
Query: 38 CPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESM 151
C TV+ C+S + +I LA + L+ G + LAGG+ ++
Sbjct: 198 CLTVDTACSSSLVAIHLACRSLRAGESDLALAGGVSAL 235
>UniRef50_Q76KZ5 Cluster: Polyketide synthase modules 4; n=1;
Streptomyces halstedii|Rep: Polyketide synthase modules
4 - Streptomyces halstedii
Length = 2260
Score = 34.3 bits (75), Expect = 2.7
Identities = 21/55 (38%), Positives = 31/55 (56%), Gaps = 4/55 (7%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSN----VPFYLKRGETSYG 196
T++ C+S + +I LAAQ L+ G + LAGG MS V F +RG ++ G
Sbjct: 201 TLDTACSSSLVAIHLAAQSLRKGECTLALAGGASVMSTPDIFVDFSRQRGLSADG 255
>UniRef50_Q6W5P8 Cluster: FscF; n=3; Streptomyces|Rep: FscF -
Streptomyces sp. FR-008
Length = 2049
Score = 34.3 bits (75), Expect = 2.7
Identities = 20/53 (37%), Positives = 30/53 (56%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSYGGM 202
TV+ C++ + +I LAAQ L+ G + LAGG+ MS + G T GG+
Sbjct: 197 TVDTACSASLVAIHLAAQALRNGECGLALAGGVTVMSTPMGF--SGFTRQGGI 247
>UniRef50_Q52V50 Cluster: Polyketide synthase type I; n=7; cellular
organisms|Rep: Polyketide synthase type I - Streptomyces
aizunensis
Length = 7510
Score = 34.3 bits (75), Expect = 2.7
Identities = 20/55 (36%), Positives = 31/55 (56%), Gaps = 4/55 (7%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSN----VPFYLKRGETSYG 196
TV+ C+S + ++ LAAQ L+ G + LAGG+ MS + F +RG + G
Sbjct: 2001 TVDTACSSSLVALHLAAQALRNGECDMALAGGVTVMSTPDTFIDFSRQRGLSGNG 2055
>UniRef50_Q4U446 Cluster: DszB; n=2; cellular organisms|Rep: DszB -
Polyangium cellulosum (Sorangium cellulosum)
Length = 6256
Score = 34.3 bits (75), Expect = 2.7
Identities = 16/42 (38%), Positives = 26/42 (61%)
Frame = +2
Query: 38 CPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVP 163
C V+ CAS + +I LA +GL G + +AGG+ ++S +P
Sbjct: 5662 CMAVDTTCASSLTAIHLACEGLLLGRTDLAIAGGV-NLSLIP 5702
>UniRef50_Q3W1F1 Cluster: Beta-ketoacyl synthase:Acyl transferase
domain; n=1; Frankia sp. EAN1pec|Rep: Beta-ketoacyl
synthase:Acyl transferase domain - Frankia sp. EAN1pec
Length = 2816
Score = 34.3 bits (75), Expect = 2.7
Identities = 15/43 (34%), Positives = 27/43 (62%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYL 172
TV+ CAS + ++ A + L GA ++L GG+++ S+V +L
Sbjct: 951 TVDAACASSLAALDAACKELSAGASDMVLCGGVDTHSSVHDFL 993
>UniRef50_Q1RS52 Cluster: Polyketide synthase type I; n=3;
Bacteria|Rep: Polyketide synthase type I - Bacillus
amyloliquefaciens
Length = 2071
Score = 34.3 bits (75), Expect = 2.7
Identities = 17/42 (40%), Positives = 24/42 (57%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFY 169
TV+ C+S + +I LA QGL T + +AGG+ S FY
Sbjct: 1031 TVDTACSSSLTAIHLACQGLWTKETEMAVAGGVFIQSTPAFY 1072
>UniRef50_Q1RS45 Cluster: Polyketide synthase type I; n=4; cellular
organisms|Rep: Polyketide synthase type I - Bacillus
amyloliquefaciens
Length = 5204
Score = 34.3 bits (75), Expect = 2.7
Identities = 14/42 (33%), Positives = 27/42 (64%)
Frame = +2
Query: 47 VNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYL 172
V+ C+S + +I LAA+ ++TGA +AGG+ +++ Y+
Sbjct: 770 VDTACSSSLTAIHLAAESIRTGASECAIAGGVNLITDPVHYI 811
>UniRef50_Q0VZ72 Cluster: Polyketide synthase; n=1; Chondromyces
crocatus|Rep: Polyketide synthase - Chondromyces
crocatus
Length = 2198
Score = 34.3 bits (75), Expect = 2.7
Identities = 15/38 (39%), Positives = 23/38 (60%)
Frame = +2
Query: 38 CPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESM 151
C TV+ C+S + S+ LA + L+ G + LAGG+ M
Sbjct: 194 CMTVDTACSSSLVSVHLACRSLRAGECDLALAGGVNLM 231
>UniRef50_Q0RTS5 Cluster: Putative Type I modular polyketide synthase;
n=1; Frankia alni ACN14a|Rep: Putative Type I modular
polyketide synthase - Frankia alni (strain ACN14a)
Length = 3139
Score = 34.3 bits (75), Expect = 2.7
Identities = 14/38 (36%), Positives = 26/38 (68%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSN 157
T++ C+S + ++ LAAQ L++G + LAGG+ M++
Sbjct: 2163 TIDTACSSSLVALHLAAQALRSGETDLALAGGVALMAS 2200
>UniRef50_Q0LKI5 Cluster: Beta-ketoacyl synthase; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: Beta-ketoacyl synthase -
Herpetosiphon aurantiacus ATCC 23779
Length = 1939
Score = 34.3 bits (75), Expect = 2.7
Identities = 19/55 (34%), Positives = 31/55 (56%), Gaps = 4/55 (7%)
Frame = +2
Query: 47 VNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVP----FYLKRGETSYGG 199
+N C+ + +I +A Q LQTG +++AGG+ + S +P F+ K G S G
Sbjct: 276 INTACSGSLVAIHMACQALQTGEADLVVAGGVNA-SLLPDGNLFFSKAGALSPDG 329
>UniRef50_A4F5D6 Cluster: Polyketide synthase; n=5; cellular
organisms|Rep: Polyketide synthase - Polyangium
cellulosum (Sorangium cellulosum)
Length = 4533
Score = 34.3 bits (75), Expect = 2.7
Identities = 14/33 (42%), Positives = 22/33 (66%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGM 142
TVN C+S + ++ LA Q L++G + LAGG+
Sbjct: 332 TVNTACSSSLVAVHLACQSLRSGESTMALAGGV 364
>UniRef50_A0ACH1 Cluster: Putative polyketide synthase B; n=5;
Bacteria|Rep: Putative polyketide synthase B -
Streptomyces ambofaciens ATCC 23877
Length = 8154
Score = 34.3 bits (75), Expect = 2.7
Identities = 16/37 (43%), Positives = 24/37 (64%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMS 154
TV+ C+S + ++ LAAQ L+ G + LAGG+ MS
Sbjct: 6749 TVDTACSSSLVALHLAAQALRRGECDLALAGGVSVMS 6785
>UniRef50_Q9EX53 Cluster: Putative type I polyketide synthase; n=1;
Streptomyces coelicolor|Rep: Putative type I polyketide
synthase - Streptomyces coelicolor
Length = 3576
Score = 33.9 bits (74), Expect = 3.6
Identities = 15/44 (34%), Positives = 28/44 (63%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLK 175
TV+ C+S + ++ +AA L++G + LAGG+ MS+ Y++
Sbjct: 1960 TVDTACSSSLVALHMAANALRSGECDLALAGGVTVMSSPTSYVE 2003
>UniRef50_Q82QT4 Cluster: Modular polyketide synthase; n=3;
Streptomyces|Rep: Modular polyketide synthase -
Streptomyces avermitilis
Length = 7746
Score = 33.9 bits (74), Expect = 3.6
Identities = 20/55 (36%), Positives = 32/55 (58%), Gaps = 4/55 (7%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSN----VPFYLKRGETSYG 196
TV+ C+S + ++ LA Q L++G + LAGG+ MS V F +RG ++ G
Sbjct: 1213 TVDTACSSSLVALHLAVQSLRSGECTMALAGGVTVMSTPGMFVEFSRQRGLSADG 1267
Score = 32.7 bits (71), Expect = 8.2
Identities = 14/44 (31%), Positives = 27/44 (61%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLK 175
TV+ C+S + ++ LAAQ L++G + L GG+ M+ +++
Sbjct: 2719 TVDTACSSSLVALHLAAQALRSGECSMALVGGVTVMTTPDLFVE 2762
Score = 32.7 bits (71), Expect = 8.2
Identities = 19/55 (34%), Positives = 32/55 (58%), Gaps = 4/55 (7%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSN----VPFYLKRGETSYG 196
TV+ C+S + ++ LAAQ L++G + L GG+ M+ V F +RG ++ G
Sbjct: 4453 TVDTACSSSLVALHLAAQALRSGECSMALVGGVTVMAGPSVFVEFSRQRGLSADG 4507
>UniRef50_Q9KIV4 Cluster: 8,8a-deoxyoleandolide synthase 1; n=1;
Streptomyces antibioticus|Rep: 8,8a-deoxyoleandolide
synthase 1 - Streptomyces antibioticus
Length = 4150
Score = 33.9 bits (74), Expect = 3.6
Identities = 15/38 (39%), Positives = 24/38 (63%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSN 157
TV+ C+S + ++ LA QGL+ G + L GG+ MS+
Sbjct: 2713 TVDTACSSSLVALHLAVQGLRRGECSLALVGGVTVMSS 2750
>UniRef50_Q8RJY6 Cluster: StiA protein; n=1; Stigmatella
aurantiaca|Rep: StiA protein - Stigmatella aurantiaca
Length = 2373
Score = 33.9 bits (74), Expect = 3.6
Identities = 18/44 (40%), Positives = 26/44 (59%)
Frame = +2
Query: 11 FAGLPKSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGM 142
F GL + P TVN C+S + ++ LA Q L+ G + LAGG+
Sbjct: 241 FLGL-RGPSL-TVNTACSSALVAVHLACQSLRNGEAAMALAGGV 282
>UniRef50_Q83WF0 Cluster: Protomycinolide IV synthase 1; n=18;
cellular organisms|Rep: Protomycinolide IV synthase 1 -
Micromonospora griseorubida
Length = 4307
Score = 33.9 bits (74), Expect = 3.6
Identities = 20/58 (34%), Positives = 32/58 (55%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSYGGMQLVDG 217
TV+ C+S + ++ LA Q L++G + LAGG+ M+ ++ E S G VDG
Sbjct: 1153 TVDTACSSSLVALHLAVQALRSGECDVALAGGVTVMATPGIFV---EFSRQGGLAVDG 1207
>UniRef50_Q83WE8 Cluster: Protomycinolide IV synthase 3; n=2;
Micromonospora griseorubida|Rep: Protomycinolide IV
synthase 3 - Micromonospora griseorubida
Length = 3649
Score = 33.9 bits (74), Expect = 3.6
Identities = 20/58 (34%), Positives = 32/58 (55%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSYGGMQLVDG 217
TV+ C+S + ++ LA Q L++G + LAGG+ M+ ++ E S G VDG
Sbjct: 202 TVDTACSSSLVALHLAVQALRSGECDVALAGGVTVMATPGIFV---EFSRQGGLAVDG 256
>UniRef50_Q6W5P9 Cluster: FscB; n=6; Streptomyces|Rep: FscB -
Streptomyces sp. FR-008
Length = 5541
Score = 33.9 bits (74), Expect = 3.6
Identities = 17/44 (38%), Positives = 27/44 (61%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLK 175
T++ C+S M ++ LA Q L+TG + LAGG+ MS Y++
Sbjct: 1767 TMDTGCSSSMVALHLALQSLRTGECTMALAGGVTVMSTPEPYVE 1810
>UniRef50_Q3S869 Cluster: Modular polyketide synthase; n=2;
Streptomyces|Rep: Modular polyketide synthase -
Streptomyces neyagawaensis
Length = 5006
Score = 33.9 bits (74), Expect = 3.6
Identities = 15/38 (39%), Positives = 25/38 (65%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSN 157
TV+ C++ + ++ LAAQ L+ G + LAGG+ MS+
Sbjct: 3363 TVDTACSASLVAVHLAAQALRAGDCSLALAGGVAVMSS 3400
>UniRef50_Q0QMN7 Cluster: Polyketide synthase type I; n=1;
Streptomyces sp. Eco86|Rep: Polyketide synthase type I -
Streptomyces sp. Eco86
Length = 4290
Score = 33.9 bits (74), Expect = 3.6
Identities = 15/37 (40%), Positives = 24/37 (64%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMS 154
TV+ C+S + ++ LAAQ L+ G + LAGG+ M+
Sbjct: 2929 TVDTACSSSLVAVHLAAQALRAGECTLALAGGVTVMA 2965
>UniRef50_A7GF25 Cluster: DNA (Cytosine-5-)-methyltransferase; n=1;
Clostridium botulinum F str. Langeland|Rep: DNA
(Cytosine-5-)-methyltransferase - Clostridium botulinum
(strain Langeland / NCTC 10281 / Type F)
Length = 547
Score = 33.9 bits (74), Expect = 3.6
Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 5/77 (6%)
Frame = +2
Query: 299 ITRQDQD----EYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNF 466
+TRQD++ + +N + + YE +A +DELV + + V+ ED+ Y N
Sbjct: 130 LTRQDENHINNDLKLNLHNKDVVLYEDEAHIDELVNMVRNNNYRSFVLLNEDQLYLLKNI 189
Query: 467 -EKFTKLSTVFQKENGT 514
+K KL F K + T
Sbjct: 190 TKKKEKLKEYFSKNSNT 206
>UniRef50_A1YAN0 Cluster: Polyketide synthase type I; n=3; cellular
organisms|Rep: Polyketide synthase type I -
Amycolatopsis orientalis
Length = 5099
Score = 33.9 bits (74), Expect = 3.6
Identities = 20/55 (36%), Positives = 31/55 (56%), Gaps = 4/55 (7%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSN----VPFYLKRGETSYG 196
T++ C+S + ++ LAAQ L+ G + LAGG+ MS V F +RG + G
Sbjct: 201 TIDTACSSSLVALHLAAQALRQGECSMALAGGVAVMSTPDTFVDFSRQRGLAADG 255
>UniRef50_A1AMI5 Cluster: Beta-ketoacyl synthase; n=1; Pelobacter
propionicus DSM 2379|Rep: Beta-ketoacyl synthase -
Pelobacter propionicus (strain DSM 2379)
Length = 392
Score = 33.9 bits (74), Expect = 3.6
Identities = 14/41 (34%), Positives = 26/41 (63%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPF 166
TV C+SG +I +A L+ G +++AGG + +++VP+
Sbjct: 147 TVVNACSSGSDAIGVALSWLKGGLCDLVIAGGADELNHVPY 187
>UniRef50_A0FCL2 Cluster: MerB; n=4; cellular organisms|Rep: MerB -
Streptomyces violaceoniger
Length = 7178
Score = 33.9 bits (74), Expect = 3.6
Identities = 21/55 (38%), Positives = 30/55 (54%), Gaps = 4/55 (7%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSN----VPFYLKRGETSYG 196
TV+ C+S + ++ LA Q L+ G + LAGG+ MS V F +RG S G
Sbjct: 1901 TVDTACSSSLVALHLAIQALRLGECSLALAGGVTVMSTPTVFVEFSRQRGLASDG 1955
>UniRef50_Q859P9 Cluster: Virion RNA polymerase; n=1; Enterobacteria
phage N4|Rep: Virion RNA polymerase - Bacteriophage N4
Length = 3500
Score = 33.9 bits (74), Expect = 3.6
Identities = 13/39 (33%), Positives = 26/39 (66%)
Frame = +2
Query: 395 VPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENG 511
+PV ++G +I A+D+E+ ++N + FT++ T +Q G
Sbjct: 2921 IPVENQQGVNLIIADDKEFAKLNSQSFTRIGT-YQGSTG 2958
>UniRef50_Q07017 Cluster: Oleandomycin polyketide synthase, modules
5 and 6; n=1; Streptomyces antibioticus|Rep:
Oleandomycin polyketide synthase, modules 5 and 6 -
Streptomyces antibioticus
Length = 3519
Score = 33.9 bits (74), Expect = 3.6
Identities = 15/38 (39%), Positives = 24/38 (63%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSN 157
TV+ C+S + ++ LA QGL+ G + L GG+ MS+
Sbjct: 205 TVDTACSSSLVALHLAVQGLRRGECSLALVGGVTVMSS 242
>UniRef50_Q93H85 Cluster: Modular polyketide synthase; n=4;
Bacteria|Rep: Modular polyketide synthase - Streptomyces
avermitilis
Length = 1835
Score = 33.5 bits (73), Expect = 4.7
Identities = 15/37 (40%), Positives = 24/37 (64%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMS 154
TV+ C+S + ++ LA Q L+TG + LAGG+ M+
Sbjct: 200 TVDTACSSSLVALHLAVQALRTGECSMALAGGVTVMA 236
>UniRef50_Q63LK8 Cluster: Putative polyketide synthase; n=30; cellular
organisms|Rep: Putative polyketide synthase -
Burkholderia pseudomallei (Pseudomonas pseudomallei)
Length = 5835
Score = 33.5 bits (73), Expect = 4.7
Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 2/74 (2%)
Frame = +2
Query: 26 KSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSYGGMQ 205
K P P V+ C+S + +I LA Q L+ G + LAGG+ + Y+ E GM
Sbjct: 987 KGPAIP-VDTACSSALVAIHLACQALRAGEIDMALAGGVTLYLSPDAYI---EMCSSGML 1042
Query: 206 LVDG--IVFDGLTD 241
DG VFD D
Sbjct: 1043 SPDGRCKVFDDSAD 1056
>UniRef50_Q5VKR4 Cluster: Type I PKS; n=7; Actinomycetales|Rep: Type I
PKS - Saccharopolyspora erythraea (Streptomyces
erythraeus)
Length = 5359
Score = 33.5 bits (73), Expect = 4.7
Identities = 16/44 (36%), Positives = 26/44 (59%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLK 175
TV+ C+S + S+ LAAQ L+ G + LAGG M+ +++
Sbjct: 2210 TVDTACSSSLVSLHLAAQALRRGECAMALAGGATVMATPGMFVE 2253
Score = 32.7 bits (71), Expect = 8.2
Identities = 15/37 (40%), Positives = 23/37 (62%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMS 154
TV+ C+S + S+ LA Q L+ G + LAGG+ M+
Sbjct: 190 TVDTACSSSLVSLHLAVQALRAGECSMALAGGVTVMA 226
>UniRef50_Q4U447 Cluster: DszA; n=4; cellular organisms|Rep: DszA -
Polyangium cellulosum (Sorangium cellulosum)
Length = 6011
Score = 33.5 bits (73), Expect = 4.7
Identities = 17/54 (31%), Positives = 30/54 (55%)
Frame = +2
Query: 26 KSPXCPTVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGET 187
K P P V+ C+S + +I LA Q L +G+ + +AGG+ M+ ++ +T
Sbjct: 3937 KGPSVP-VDTACSSSLMAIHLACQSLISGSSDLAVAGGVALMTTPVSHIMLSKT 3989
>UniRef50_Q2N3S8 Cluster: Polyketide synthase; n=2; Bacteria|Rep:
Polyketide synthase - Polyangium cellulosum (Sorangium
cellulosum)
Length = 4839
Score = 33.5 bits (73), Expect = 4.7
Identities = 16/47 (34%), Positives = 29/47 (61%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGE 184
T+N C+S + +I +A Q L +G ++LAGG+ M++ F+ G+
Sbjct: 2941 TINGACSSSLIAIHMACQALWSGEVDLMLAGGVCLMTSHHFHEVAGK 2987
>UniRef50_Q0PD02 Cluster: Type I polyketide synthase; n=2;
Streptomyces halstedii|Rep: Type I polyketide synthase -
Streptomyces halstedii
Length = 5220
Score = 33.5 bits (73), Expect = 4.7
Identities = 16/37 (43%), Positives = 23/37 (62%)
Frame = +2
Query: 44 TVNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMS 154
TV+ C+S + ++ LA Q L+ G I LAGG+ MS
Sbjct: 1760 TVDTACSSSLVALHLAGQALRQGECSIALAGGVTVMS 1796
>UniRef50_Q0B307 Cluster: Beta-ketoacyl synthase; n=1; Burkholderia
ambifaria AMMD|Rep: Beta-ketoacyl synthase - Burkholderia
cepacia (strain ATCC 53795 / AMMD)
Length = 2985
Score = 33.5 bits (73), Expect = 4.7
Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 2/85 (2%)
Frame = +2
Query: 47 VNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSYGGMQLVDG--I 220
V+ C+S + ++ LA Q L+ G I LAGG+ + + + S GGM DG
Sbjct: 1673 VDTACSSSLMALHLAVQALRRGECSIALAGGVNLLLSAETSVL---LSKGGMLAPDGRCK 1729
Query: 221 VFDGLTDVYNKFHMGNCAENTAKKL 295
FD D Y + CA K+L
Sbjct: 1730 TFDAAADGYVRSE--GCAMVVLKRL 1752
>UniRef50_Q09DD3 Cluster: MxaC; n=1; Stigmatella aurantiaca
DW4/3-1|Rep: MxaC - Stigmatella aurantiaca DW4/3-1
Length = 1392
Score = 33.5 bits (73), Expect = 4.7
Identities = 20/67 (29%), Positives = 33/67 (49%)
Frame = +2
Query: 47 VNKVCASGMKSIMLAAQGLQTGAQXIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVF 226
V CAS + ++ +A+ L++G ++LAGGM + V + S+GG+ F
Sbjct: 690 VESACASSLAALEIASNQLRSGQCDMMLAGGMYASLGVDALSQC--CSFGGLSQNGSFPF 747
Query: 227 DGLTDVY 247
D D Y
Sbjct: 748 DARADGY 754
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 584,130,814
Number of Sequences: 1657284
Number of extensions: 10416938
Number of successful extensions: 34073
Number of sequences better than 10.0: 303
Number of HSP's better than 10.0 without gapping: 32253
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 33865
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 51239674196
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -